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Search of human proteins with 24308049
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308049 peptidylprolyl isomerase domain and WD repeat
containing 1 [Homo sapiens]
(646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308049 peptidylprolyl isomerase domain and WD repeat contai... 1314 0.0
gi|19557636 peptidylprolyl isomerase-like 3 isoform PPIL3b [Homo... 167 3e-41
gi|19557640 peptidylprolyl isomerase-like 3 isoform PPIL3b [Homo... 167 3e-41
gi|7706339 peptidylprolyl isomerase-like 1 [Homo sapiens] 166 5e-41
gi|22547215 peptidylprolyl isomerase-like 2 isoform b [Homo sapi... 152 7e-37
gi|22547212 peptidylprolyl isomerase-like 2 isoform a [Homo sapi... 152 7e-37
gi|7657473 peptidylprolyl isomerase-like 2 isoform a [Homo sapiens] 152 7e-37
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 135 9e-32
gi|64276486 serologically defined colon cancer antigen 10 [Homo ... 131 2e-30
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 130 3e-30
gi|4758950 peptidylprolyl isomerase B precursor [Homo sapiens] 129 1e-29
gi|4826932 peptidylprolyl isomerase D [Homo sapiens] 124 2e-28
gi|10863927 peptidylprolyl isomerase A [Homo sapiens] 121 2e-27
gi|5031987 peptidylprolyl isomerase F precursor [Homo sapiens] 121 2e-27
gi|45439316 peptidylprolyl isomerase E isoform 2 [Homo sapiens] 121 2e-27
gi|45439318 peptidylprolyl isomerase E isoform 3 [Homo sapiens] 120 5e-27
gi|5174637 peptidylprolyl isomerase E isoform 1 [Homo sapiens] 120 5e-27
gi|4505991 peptidylprolyl isomerase C [Homo sapiens] 118 2e-26
gi|169164370 PREDICTED: similar to TRIMCyp isoform 1 [Homo sapiens] 114 3e-25
gi|88958081 PREDICTED: similar to TRIMCyp isoform 2 [Homo sapiens] 114 3e-25
gi|88953813 PREDICTED: similar to peptidylprolyl isomerase A iso... 114 3e-25
gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens] 112 8e-25
gi|5454154 peptidylprolyl isomerase H [Homo sapiens] 112 1e-24
gi|14277126 peptidylprolyl isomerase-like 3 isoform PPIL3a [Homo... 108 2e-23
gi|221139811 peptidylprolyl isomerase A (cyclophilin A)-like 4E ... 107 4e-23
gi|169163623 PREDICTED: similar to TRIM5/CypA fusion protein [Ho... 106 6e-23
gi|169164185 PREDICTED: similar to TRIM5/CypA fusion protein [Ho... 106 6e-23
gi|169163387 PREDICTED: similar to TRIM5/CypA fusion protein [Ho... 106 6e-23
gi|178057341 peptidylprolyl isomerase A (cyclophilin A)-like 4G ... 105 1e-22
gi|219842199 peptidylprolyl isomerase A (cyclophilin A)-like 4B ... 103 4e-22
>gi|24308049 peptidylprolyl isomerase domain and WD repeat
containing 1 [Homo sapiens]
Length = 646
Score = 1314 bits (3401), Expect = 0.0
Identities = 646/646 (100%), Positives = 646/646 (100%)
Query: 1 MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATL 60
MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATL
Sbjct: 1 MAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATL 60
Query: 61 AKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIE 120
AKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIE
Sbjct: 61 AKKRKVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIE 120
Query: 121 EGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQC 180
EGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQC
Sbjct: 121 EGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQC 180
Query: 181 EWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVS 240
EWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVS
Sbjct: 181 EWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVS 240
Query: 241 SDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGS 300
SDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGS
Sbjct: 241 SDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGS 300
Query: 301 DRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLIN 360
DRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLIN
Sbjct: 301 DRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLIN 360
Query: 361 IVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIE 420
IVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIE
Sbjct: 361 IVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIE 420
Query: 421 MKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMA 480
MKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMA
Sbjct: 421 MKASENPVLQNIQADPTIVCTSFKKNRFYMFTKREPEDTKSADSDRDVFNEKPSKEEVMA 480
Query: 481 ATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGF 540
ATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGF
Sbjct: 481 ATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGF 540
Query: 541 MIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTP 600
MIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTP
Sbjct: 541 MIQTGDPTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTP 600
Query: 601 WLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK 646
WLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK
Sbjct: 601 WLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITVK 646
>gi|19557636 peptidylprolyl isomerase-like 3 isoform PPIL3b [Homo
sapiens]
Length = 161
Score = 167 bits (423), Expect = 3e-41
Identities = 82/153 (53%), Positives = 102/153 (66%)
Query: 493 SAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGM 552
S +HT +GDI ++F PKT ENF + YYNG FHR IKGFM+QTGDPTGTG
Sbjct: 2 SVTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTGR 61
Query: 553 GGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRV 612
GG SIWG +FEDE+ L+H+ +SMAN G NTNGSQFFIT P LD K+TVFG+V
Sbjct: 62 GGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKV 121
Query: 613 TKGMEVVQRISNVKVNPKTDKPYEDVSIINITV 645
G+E + + + VN KT +P DV I +IT+
Sbjct: 122 IDGLETLDELEKLPVNEKTYRPLNDVHIKDITI 154
>gi|19557640 peptidylprolyl isomerase-like 3 isoform PPIL3b [Homo
sapiens]
Length = 161
Score = 167 bits (423), Expect = 3e-41
Identities = 82/153 (53%), Positives = 102/153 (66%)
Query: 493 SAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGM 552
S +HT +GDI ++F PKT ENF + YYNG FHR IKGFM+QTGDPTGTG
Sbjct: 2 SVTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTGR 61
Query: 553 GGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRV 612
GG SIWG +FEDE+ L+H+ +SMAN G NTNGSQFFIT P LD K+TVFG+V
Sbjct: 62 GGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTVFGKV 121
Query: 613 TKGMEVVQRISNVKVNPKTDKPYEDVSIINITV 645
G+E + + + VN KT +P DV I +IT+
Sbjct: 122 IDGLETLDELEKLPVNEKTYRPLNDVHIKDITI 154
>gi|7706339 peptidylprolyl isomerase-like 1 [Homo sapiens]
Length = 166
Score = 166 bits (421), Expect = 5e-41
Identities = 82/146 (56%), Positives = 103/146 (70%), Gaps = 1/146 (0%)
Query: 496 IHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGE 555
+ TSMG I +L+ PKT +NF +R GYYNG FHRIIK FMIQ GDPTGTG GG
Sbjct: 16 LETSMGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGA 75
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
SI+G +FEDE H L+ L+MANAG +TNGSQFF+T+ PT WLD KHT+FGRV +G
Sbjct: 76 SIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQG 135
Query: 616 MEVVQRISNVKVNPKTDKPYEDVSII 641
+ +V R+ V+ N + D+P +DV II
Sbjct: 136 IGMVNRVGMVETNSQ-DRPVDDVKII 160
>gi|22547215 peptidylprolyl isomerase-like 2 isoform b [Homo
sapiens]
Length = 527
Score = 152 bits (385), Expect = 7e-37
Identities = 76/150 (50%), Positives = 98/150 (65%)
Query: 496 IHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGE 555
+HT+ GD++ +L PKT ENF + YY+G FHR I+ F+IQ GDPTGTG GGE
Sbjct: 284 LHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQGGDPTGTGTGGE 343
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
S WG F+DEF L H LSMAN+G N+N SQFFIT +LD KHT+FGRV G
Sbjct: 344 SYWGKPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITFRSCAYLDKKHTIFGRVVGG 403
Query: 616 MEVVQRISNVKVNPKTDKPYEDVSIINITV 645
+V+ + NV+ +PKTD+P E++ I TV
Sbjct: 404 FDVLTAMENVESDPKTDRPKEEIRIDATTV 433
>gi|22547212 peptidylprolyl isomerase-like 2 isoform a [Homo
sapiens]
Length = 520
Score = 152 bits (385), Expect = 7e-37
Identities = 76/150 (50%), Positives = 98/150 (65%)
Query: 496 IHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGE 555
+HT+ GD++ +L PKT ENF + YY+G FHR I+ F+IQ GDPTGTG GGE
Sbjct: 284 LHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQGGDPTGTGTGGE 343
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
S WG F+DEF L H LSMAN+G N+N SQFFIT +LD KHT+FGRV G
Sbjct: 344 SYWGKPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITFRSCAYLDKKHTIFGRVVGG 403
Query: 616 MEVVQRISNVKVNPKTDKPYEDVSIINITV 645
+V+ + NV+ +PKTD+P E++ I TV
Sbjct: 404 FDVLTAMENVESDPKTDRPKEEIRIDATTV 433
>gi|7657473 peptidylprolyl isomerase-like 2 isoform a [Homo sapiens]
Length = 520
Score = 152 bits (385), Expect = 7e-37
Identities = 76/150 (50%), Positives = 98/150 (65%)
Query: 496 IHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGGE 555
+HT+ GD++ +L PKT ENF + YY+G FHR I+ F+IQ GDPTGTG GGE
Sbjct: 284 LHTNKGDLNLELHCDLTPKTCENFIRLCKKHYYDGTIFHRSIRNFVIQGGDPTGTGTGGE 343
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
S WG F+DEF L H LSMAN+G N+N SQFFIT +LD KHT+FGRV G
Sbjct: 344 SYWGKPFKDEFRPNLSHTGRGILSMANSGPNSNRSQFFITFRSCAYLDKKHTIFGRVVGG 403
Query: 616 MEVVQRISNVKVNPKTDKPYEDVSIINITV 645
+V+ + NV+ +PKTD+P E++ I TV
Sbjct: 404 FDVLTAMENVESDPKTDRPKEEIRIDATTV 433
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 135 bits (341), Expect = 9e-32
Identities = 79/166 (47%), Positives = 100/166 (60%), Gaps = 14/166 (8%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENF-CVHS----------RNGYYNGHTFHRIIKGF 540
D I +G I +LF CPKT +NF C+ S + Y G TFHR++K F
Sbjct: 12 DIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNF 71
Query: 541 MIQTGD-PTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPT 599
MIQ GD G G GGESI+GG F+DE + L+HDR + LSMAN G +TNGSQFFIT P
Sbjct: 72 MIQGGDFSEGNGKGGESIYGGYFKDE-NFILKHDRAFLLSMANRGKHTNGSQFFITTKPA 130
Query: 600 PWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITV 645
P LD H VFG V G EV+++I N+K + +PY DV +I+ V
Sbjct: 131 PHLDGVHVVFGLVISGFEVIEQIENLKTD-AASRPYADVRVIDCGV 175
>gi|64276486 serologically defined colon cancer antigen 10 [Homo
sapiens]
Length = 472
Score = 131 bits (330), Expect = 2e-30
Identities = 62/119 (52%), Positives = 82/119 (68%)
Query: 495 IIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGMGG 554
++ T+ GDI +L+ E PK NF YY+ FHR++ GF++Q GDPTGTG GG
Sbjct: 16 LLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPGFIVQGGDPTGTGSGG 75
Query: 555 ESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVT 613
ESI+G F+DEFHS LR +R ++MANAGS+ NGSQFF T+ L+NKHT+FG+VT
Sbjct: 76 ESIYGAPFKDEFHSRLRFNRRGLVAMANAGSHDNGSQFFFTLGRADELNNKHTIFGKVT 134
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 130 bits (328), Expect = 3e-30
Identities = 75/172 (43%), Positives = 101/172 (58%), Gaps = 14/172 (8%)
Query: 483 QAEGPKRVSDSAIIHTSMGDIHTKLFPVECPKTVENF---CVHSRNG--------YYNGH 531
+ + P+ D AI + G + +LF CPKT ENF C + +Y
Sbjct: 4 KVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSC 63
Query: 532 TFHRIIKGFMIQTGD-PTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGS 590
FHR++K FM+Q GD G G GGESI+GG FEDE + ++H++ + LSMAN G +TNGS
Sbjct: 64 LFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFA-VKHNKEFLLSMANRGKDTNGS 122
Query: 591 QFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIIN 642
QFFIT PTP LD H VFG+V G EVV+ I N K + KP+ +V I++
Sbjct: 123 QFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTD-AASKPFAEVRILS 173
>gi|4758950 peptidylprolyl isomerase B precursor [Homo sapiens]
Length = 216
Score = 129 bits (323), Expect = 1e-29
Identities = 76/153 (49%), Positives = 97/153 (63%), Gaps = 6/153 (3%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPT 548
D I +G + LF PKTV+NF + G+ Y FHR+IK FMIQ GD T
Sbjct: 49 DLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFT 108
Query: 549 -GTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHT 607
G G GG+SI+G F DE + L+H P +SMANAG +TNGSQFFIT V T WLD KH
Sbjct: 109 RGDGTGGKSIYGERFPDE-NFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHV 167
Query: 608 VFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSI 640
VFG+V +GMEVV+++ + K + + DKP +DV I
Sbjct: 168 VFGKVLEGMEVVRKVESTKTDSR-DKPLKDVII 199
>gi|4826932 peptidylprolyl isomerase D [Homo sapiens]
Length = 370
Score = 124 bits (312), Expect = 2e-28
Identities = 82/161 (50%), Positives = 95/161 (59%), Gaps = 17/161 (10%)
Query: 487 PKRVSDSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHT-----------FHR 535
P+ D I +G I +LF PKT ENF GHT FHR
Sbjct: 16 PRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGHTTGKPLHFKGCPFHR 75
Query: 536 IIKGFMIQTGDPTG-TGMGGESIWGGEFEDE-FHSTLRHDRPYTLSMANAGSNTNGSQFF 593
IIK FMIQ GD + G GGESI+G +FEDE FH +HDR LSMANAG NTNGSQFF
Sbjct: 76 IIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFH--YKHDREGLLSMANAGRNTNGSQFF 133
Query: 594 ITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPKTDKP 634
IT VPTP LD KH VFG+V KG+ V + + NV+V K +KP
Sbjct: 134 ITTVPTPHLDGKHVVFGQVIKGIGVARILENVEV--KGEKP 172
>gi|10863927 peptidylprolyl isomerase A [Homo sapiens]
Length = 165
Score = 121 bits (304), Expect = 2e-27
Identities = 73/147 (49%), Positives = 89/147 (60%), Gaps = 6/147 (4%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPT 548
D A+ +G + +LF + PKT ENF S G+ Y G FHRII GFM Q GD T
Sbjct: 9 DIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFT 68
Query: 549 G-TGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHT 607
G GG+SI+G +FEDE + L+H P LSMANAG NTNGSQFFI T WLD KH
Sbjct: 69 RHNGTGGKSIYGEKFEDE-NFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHV 127
Query: 608 VFGRVTKGMEVVQRISNV-KVNPKTDK 633
VFG+V +GM +V+ + N KT K
Sbjct: 128 VFGKVKEGMNIVEAMERFGSRNGKTSK 154
>gi|5031987 peptidylprolyl isomerase F precursor [Homo sapiens]
Length = 207
Score = 121 bits (304), Expect = 2e-27
Identities = 64/116 (55%), Positives = 76/116 (65%), Gaps = 5/116 (4%)
Query: 513 PKTVENF---CVHSRNGYYNGHTFHRIIKGFMIQTGDPTG-TGMGGESIWGGEFEDEFHS 568
PKT ENF C + Y G TFHR+I FM Q GD T G GG+SI+G F DE +
Sbjct: 72 PKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDE-NF 130
Query: 569 TLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISN 624
TL+H P LSMANAG NTNGSQFFI + T WLD KH VFG V +GM+VV++I +
Sbjct: 131 TLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIES 186
>gi|45439316 peptidylprolyl isomerase E isoform 2 [Homo sapiens]
Length = 296
Score = 121 bits (304), Expect = 2e-27
Identities = 73/184 (39%), Positives = 102/184 (55%), Gaps = 10/184 (5%)
Query: 460 KSADSDRDVFNEKPSKEEV-----MAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPK 514
K+ + +++ +P K E +A P+ D I + G I L P
Sbjct: 108 KTLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPM 167
Query: 515 TVENF---CVHSRNGYYNGHTFHRIIKGFMIQTGDPTG-TGMGGESIWGGEFEDEFHSTL 570
T ENF C H + + G +FHRII FM Q GD T G GG+SI+G +F+DE + L
Sbjct: 168 TAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDE-NFIL 226
Query: 571 RHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPK 630
+H P LSMAN+G NTNGSQFF+T T WLD KH VFG VT+G++V+++I + +
Sbjct: 227 KHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIEKQEESAI 286
Query: 631 TDKP 634
T +P
Sbjct: 287 TSQP 290
>gi|45439318 peptidylprolyl isomerase E isoform 3 [Homo sapiens]
Length = 235
Score = 120 bits (300), Expect = 5e-27
Identities = 76/190 (40%), Positives = 103/190 (54%), Gaps = 12/190 (6%)
Query: 460 KSADSDRDVFNEKPSKEEV-----MAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPK 514
K+ + +++ +P K E +A P+ D I + G I L P
Sbjct: 42 KTLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPM 101
Query: 515 TVENF---CVHSRNGYYNGHTFHRIIKGFMIQTGDPTG-TGMGGESIWGGEFEDEFHSTL 570
T ENF C H + + G +FHRII FM Q GD T G GG+SI+G +F+DE + L
Sbjct: 102 TAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDE-NFIL 160
Query: 571 RHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPK 630
+H P LSMAN+G NTNGSQFF+T T WLD KH VFG VT+G++V+++I K
Sbjct: 161 KHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIE--AQGSK 218
Query: 631 TDKPYEDVSI 640
KP + V I
Sbjct: 219 DGKPKQKVII 228
>gi|5174637 peptidylprolyl isomerase E isoform 1 [Homo sapiens]
Length = 301
Score = 120 bits (300), Expect = 5e-27
Identities = 76/190 (40%), Positives = 103/190 (54%), Gaps = 12/190 (6%)
Query: 460 KSADSDRDVFNEKPSKEEV-----MAATQAEGPKRVSDSAIIHTSMGDIHTKLFPVECPK 514
K+ + +++ +P K E +A P+ D I + G I L P
Sbjct: 108 KTLEENKEEEGSEPPKAETQEGEPIAKKARSNPQVYMDIKIGNKPAGRIQMLLRSDVVPM 167
Query: 515 TVENF---CVHSRNGYYNGHTFHRIIKGFMIQTGDPTG-TGMGGESIWGGEFEDEFHSTL 570
T ENF C H + + G +FHRII FM Q GD T G GG+SI+G +F+DE + L
Sbjct: 168 TAENFRCLCTHEKGFGFKGSSFHRIIPQFMCQGGDFTNHNGTGGKSIYGKKFDDE-NFIL 226
Query: 571 RHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKGMEVVQRISNVKVNPK 630
+H P LSMAN+G NTNGSQFF+T T WLD KH VFG VT+G++V+++I K
Sbjct: 227 KHTGPGLLSMANSGPNTNGSQFFLTCDKTDWLDGKHVVFGEVTEGLDVLRQIE--AQGSK 284
Query: 631 TDKPYEDVSI 640
KP + V I
Sbjct: 285 DGKPKQKVII 294
>gi|4505991 peptidylprolyl isomerase C [Homo sapiens]
Length = 212
Score = 118 bits (295), Expect = 2e-26
Identities = 76/155 (49%), Positives = 90/155 (58%), Gaps = 6/155 (3%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGD-P 547
D I +G I LF PKTVENF + GY Y G FHR+IK FMIQ GD
Sbjct: 43 DVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDIT 102
Query: 548 TGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHT 607
TG G GG SI+G F DE + L+H +SMANAG +TNGSQFFIT+ WLD KH
Sbjct: 103 TGDGTGGVSIYGETFPDE-NFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHV 161
Query: 608 VFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIIN 642
VFG+V GM VV I ++ D+P + SIIN
Sbjct: 162 VFGKVIDGMTVVHSI-ELQATDGHDRPLTNCSIIN 195
>gi|169164370 PREDICTED: similar to TRIMCyp isoform 1 [Homo sapiens]
Length = 165
Score = 114 bits (285), Expect = 3e-25
Identities = 67/140 (47%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Query: 499 SMGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPTG-TGMGG 554
S+G I +LF + PKT ENFC + G+ Y G FHRII GFM GD T G GG
Sbjct: 16 SLGRISFELFADKFPKTAENFCALNTGEKGFGYKGCCFHRIIPGFMCHGGDFTHHNGTGG 75
Query: 555 ESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTK 614
+SI+G + +D+ + L+H P LSMANAG NTNGSQFFI + WLD+KH V G+V +
Sbjct: 76 KSIYGEKVDDD-NFILKHTGPGILSMANAGPNTNGSQFFICTAKSEWLDSKHVVIGKVKE 134
Query: 615 GMEVVQRISNV-KVNPKTDK 633
GM +V+ + + N KT K
Sbjct: 135 GMNIVEAMEHFGSRNGKTSK 154
>gi|88958081 PREDICTED: similar to TRIMCyp isoform 2 [Homo sapiens]
Length = 165
Score = 114 bits (285), Expect = 3e-25
Identities = 67/140 (47%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Query: 499 SMGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPTG-TGMGG 554
S+G I +LF + PKT ENFC + G+ Y G FHRII GFM GD T G GG
Sbjct: 16 SLGRISFELFADKFPKTAENFCALNTGEKGFGYKGCCFHRIIPGFMCHGGDFTHHNGTGG 75
Query: 555 ESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTK 614
+SI+G + +D+ + L+H P LSMANAG NTNGSQFFI + WLD+KH V G+V +
Sbjct: 76 KSIYGEKVDDD-NFILKHTGPGILSMANAGPNTNGSQFFICTAKSEWLDSKHVVIGKVKE 134
Query: 615 GMEVVQRISNV-KVNPKTDK 633
GM +V+ + + N KT K
Sbjct: 135 GMNIVEAMEHFGSRNGKTSK 154
>gi|88953813 PREDICTED: similar to peptidylprolyl isomerase A
isoform 2 [Homo sapiens]
Length = 165
Score = 114 bits (285), Expect = 3e-25
Identities = 67/140 (47%), Positives = 87/140 (62%), Gaps = 6/140 (4%)
Query: 499 SMGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPTG-TGMGG 554
S+G I +LF + PKT ENFC + G+ Y G FHRII GFM GD T G GG
Sbjct: 16 SLGRISFELFADKFPKTAENFCALNTGEKGFGYKGCCFHRIIPGFMCHGGDFTHHNGTGG 75
Query: 555 ESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTK 614
+SI+G + +D+ + L+H P LSMANAG NTNGSQFFI + WLD+KH V G+V +
Sbjct: 76 KSIYGEKVDDD-NFILKHTGPGILSMANAGPNTNGSQFFICTAKSEWLDSKHVVIGKVKE 134
Query: 615 GMEVVQRISNV-KVNPKTDK 633
GM +V+ + + N KT K
Sbjct: 135 GMNIVEAMEHFGSRNGKTSK 154
>gi|20911035 peptidylprolyl isomerase-like 4 [Homo sapiens]
Length = 492
Score = 112 bits (281), Expect = 8e-25
Identities = 63/156 (40%), Positives = 93/156 (59%), Gaps = 9/156 (5%)
Query: 493 SAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGYYNGHTFHRIIKGFMIQTGDPTGTGM 552
+ ++ T++GD+ L+ E P+ NF + YYN H + + F+IQTGDPTGTG
Sbjct: 2 AVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTGR 61
Query: 553 GGESIWG-------GEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPT-PWLDN 604
GGESI+G FE E ++H + T+SM N GS+ +GSQF IT +LD
Sbjct: 62 GGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLDG 121
Query: 605 KHTVFGRVTKGMEVVQRISNVKVNPKTDKPYEDVSI 640
HTVFG VT+GM+++++I+ V+ K PY+D+ I
Sbjct: 122 VHTVFGEVTEGMDIIKKINETFVD-KDFVPYQDIRI 156
>gi|5454154 peptidylprolyl isomerase H [Homo sapiens]
Length = 177
Score = 112 bits (280), Expect = 1e-24
Identities = 68/152 (44%), Positives = 85/152 (55%), Gaps = 11/152 (7%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGY--------YNGHTFHRIIKGFMIQ 543
D +I +G + +LF PKT ENF + Y G TFHR+IK FMIQ
Sbjct: 16 DVSIGGQEVGRMKIELFADVVPKTAENFRQFCTGEFRKDGVPIGYKGSTFHRVIKDFMIQ 75
Query: 544 TGD-PTGTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWL 602
GD G G G SI+ G F DE + LRH P LSMAN+G +TNG QFFIT WL
Sbjct: 76 GGDFVNGDGTGVASIYRGPFADE-NFKLRHSAPGLLSMANSGPSTNGCQFFITCSKCDWL 134
Query: 603 DNKHTVFGRVTKGMEVVQRISNVKVNPKTDKP 634
D KH VFG++ G+ V+++I NV P +KP
Sbjct: 135 DGKHVVFGKIIDGLLVMRKIENVPTGP-NNKP 165
>gi|14277126 peptidylprolyl isomerase-like 3 isoform PPIL3a [Homo
sapiens]
Length = 165
Score = 108 bits (270), Expect = 2e-23
Identities = 65/157 (41%), Positives = 88/157 (56%), Gaps = 4/157 (2%)
Query: 493 SAIIHTSMGDIHTKLFPVECPKT--VENFCVHSRNGYYNG-HTFHRIIKGF-MIQTGDPT 548
S +HT +GDI ++F PKT +E+ CV + + GF +
Sbjct: 2 SVTLHTDVGDIKIEVFCERTPKTCEMESRCVPQAGVQWRDLGSLQPPPPGFKQVFCLSLP 61
Query: 549 GTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTV 608
TG GG SIWG +FEDE+ L+H+ +SMAN G NTNGSQFFIT P LD K+TV
Sbjct: 62 RTGRGGNSIWGKKFEDEYSEYLKHNVRGVVSMANNGPNTNGSQFFITYGKQPHLDMKYTV 121
Query: 609 FGRVTKGMEVVQRISNVKVNPKTDKPYEDVSIINITV 645
FG+V G+E + + + VN KT +P DV I +IT+
Sbjct: 122 FGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITI 158
>gi|221139811 peptidylprolyl isomerase A (cyclophilin A)-like 4E
[Homo sapiens]
Length = 164
Score = 107 bits (266), Expect = 4e-23
Identities = 66/139 (47%), Positives = 81/139 (58%), Gaps = 6/139 (4%)
Query: 500 MGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPTG-TGMGGE 555
+G I KLF + PKT ENF S G+ Y G FHRII GFM Q GD T G G +
Sbjct: 17 LGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDK 76
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
SI+G +F+DE + +H LSMANAG NTNGSQFFI T WLD KH FG+V +
Sbjct: 77 SIYGEKFDDE-NLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKER 135
Query: 616 MEVVQRISNVKV-NPKTDK 633
+ +V+ + N KT K
Sbjct: 136 VNIVEATEHFGYRNSKTSK 154
>gi|169163623 PREDICTED: similar to TRIM5/CypA fusion protein [Homo
sapiens]
Length = 234
Score = 106 bits (265), Expect = 6e-23
Identities = 64/147 (43%), Positives = 84/147 (57%), Gaps = 6/147 (4%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGY---YNGHTFHRIIKGFMIQTGDPT 548
D ++ +G + ++F + KT +NF S Y G FHRII GFM Q GD T
Sbjct: 9 DISVSGKPLGHVSFRIFADKLSKTAQNFRALSTGEKGLDYKGSCFHRIIPGFMCQGGDFT 68
Query: 549 -GTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHT 607
G GG+S++G +F+DE + L+ RP LSMA AG NTNGSQFFI T WL KH
Sbjct: 69 YNNGTGGKSLYGEKFDDE-NFILKRIRPGILSMAKAGPNTNGSQFFICTAXTEWLIGKHV 127
Query: 608 VFGRVTKGMEVVQRISNV-KVNPKTDK 633
VFG+V +GM +V+ + N KT K
Sbjct: 128 VFGKVKEGMNIVEAMEPFGSRNGKTSK 154
>gi|169164185 PREDICTED: similar to TRIM5/CypA fusion protein [Homo
sapiens]
Length = 234
Score = 106 bits (265), Expect = 6e-23
Identities = 64/147 (43%), Positives = 84/147 (57%), Gaps = 6/147 (4%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGY---YNGHTFHRIIKGFMIQTGDPT 548
D ++ +G + ++F + KT +NF S Y G FHRII GFM Q GD T
Sbjct: 9 DISVSGKPLGHVSFRIFADKLSKTAQNFRALSTGEKGLDYKGSCFHRIIPGFMCQGGDFT 68
Query: 549 -GTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHT 607
G GG+S++G +F+DE + L+ RP LSMA AG NTNGSQFFI T WL KH
Sbjct: 69 YNNGTGGKSLYGEKFDDE-NFILKRIRPGILSMAKAGPNTNGSQFFICTAXTEWLIGKHV 127
Query: 608 VFGRVTKGMEVVQRISNV-KVNPKTDK 633
VFG+V +GM +V+ + N KT K
Sbjct: 128 VFGKVKEGMNIVEAMEPFGSRNGKTSK 154
>gi|169163387 PREDICTED: similar to TRIM5/CypA fusion protein [Homo
sapiens]
Length = 272
Score = 106 bits (265), Expect = 6e-23
Identities = 64/147 (43%), Positives = 84/147 (57%), Gaps = 6/147 (4%)
Query: 492 DSAIIHTSMGDIHTKLFPVECPKTVENFCVHSRNGY---YNGHTFHRIIKGFMIQTGDPT 548
D ++ +G + ++F + KT +NF S Y G FHRII GFM Q GD T
Sbjct: 9 DISVSGKPLGHVSFRIFADKLSKTAQNFRALSTGEKGLDYKGSCFHRIIPGFMCQGGDFT 68
Query: 549 -GTGMGGESIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHT 607
G GG+S++G +F+DE + L+ RP LSMA AG NTNGSQFFI T WL KH
Sbjct: 69 YNNGTGGKSLYGEKFDDE-NFILKRIRPGILSMAKAGPNTNGSQFFICTAKTEWLIGKHV 127
Query: 608 VFGRVTKGMEVVQRISNV-KVNPKTDK 633
VFG+V +GM +V+ + N KT K
Sbjct: 128 VFGKVKEGMNIVEAMEPFGSRNGKTSK 154
>gi|178057341 peptidylprolyl isomerase A (cyclophilin A)-like 4G
[Homo sapiens]
Length = 164
Score = 105 bits (262), Expect = 1e-22
Identities = 65/139 (46%), Positives = 81/139 (58%), Gaps = 6/139 (4%)
Query: 500 MGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPTG-TGMGGE 555
+G I K F + PKT ENF S G+ Y G FHRII GFM Q GD T G G +
Sbjct: 17 LGRISIKQFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTHPNGTGDK 76
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
SI+G +F+DE + +H LSMANAG NTNGSQFFI T WLD KH FG+V +
Sbjct: 77 SIYGEKFDDE-NLIRKHTGSGILSMANAGPNTNGSQFFICTAKTEWLDGKHVAFGKVKER 135
Query: 616 MEVVQRISNVKV-NPKTDK 633
+ +V+ + + N KT K
Sbjct: 136 VNIVEAMEHFGYRNSKTSK 154
>gi|219842199 peptidylprolyl isomerase A (cyclophilin A)-like 4B
[Homo sapiens]
Length = 164
Score = 103 bits (258), Expect = 4e-22
Identities = 65/139 (46%), Positives = 81/139 (58%), Gaps = 6/139 (4%)
Query: 500 MGDIHTKLFPVECPKTVENFCVHS--RNGY-YNGHTFHRIIKGFMIQTGDPTG-TGMGGE 555
+G I KLF + KT ENF S G+ Y G FHRII GFM Q GD T G G +
Sbjct: 17 LGRISIKLFADKILKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRHNGTGDK 76
Query: 556 SIWGGEFEDEFHSTLRHDRPYTLSMANAGSNTNGSQFFITVVPTPWLDNKHTVFGRVTKG 615
SI+G +F+DE + +H LSMANAG NTNGSQFFI T WLD KH FG+V +
Sbjct: 77 SIYGEKFDDE-NLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKER 135
Query: 616 MEVVQRISNVKV-NPKTDK 633
+ +V+ + + N KT K
Sbjct: 136 VNIVEAMEHFGYRNSKTSK 154
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,691,151
Number of Sequences: 37866
Number of extensions: 1129894
Number of successful extensions: 4056
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 3596
Number of HSP's gapped (non-prelim): 389
length of query: 646
length of database: 18,247,518
effective HSP length: 109
effective length of query: 537
effective length of database: 14,120,124
effective search space: 7582506588
effective search space used: 7582506588
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.