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Search of human proteins with 24025682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24025682 F-box and leucine-rich repeat protein 16 [Homo
sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens] 977 0.0
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens] 123 4e-28
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens] 121 1e-27
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens] 107 2e-23
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens] 100 2e-21
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ... 87 3e-17
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ... 72 1e-12
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi... 61 3e-09
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [... 60 6e-09
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [... 60 6e-09
gi|254039600 F-box and leucine-rich repeat protein 17 [Homo sapi... 59 7e-09
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ... 57 4e-08
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi... 54 4e-07
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens] 54 4e-07
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens] 54 4e-07
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens] 52 9e-07
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens] 52 2e-06
gi|8922303 ATP5S-like [Homo sapiens] 51 3e-06
gi|38348406 leucine rich repeat containing 33 [Homo sapiens] 47 4e-05
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H... 47 5e-05
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ... 46 7e-05
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H... 46 9e-05
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ... 45 1e-04
gi|146134388 YLP motif containing 1 [Homo sapiens] 45 1e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni... 44 2e-04
gi|119508426 alpha 3 type IX collagen [Homo sapiens] 44 3e-04
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 44 4e-04
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 44 4e-04
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 44 4e-04
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 44 4e-04
>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
Length = 479
Score = 977 bits (2525), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSL 60
MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSL
Sbjct: 1 MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSL 60
Query: 61 AAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNGLFWYFSACEKCVLAQV 120
AAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNGLFWYFSACEKCVLAQV
Sbjct: 61 AAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNGLFWYFSACEKCVLAQV 120
Query: 121 CKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLD 180
CKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLD
Sbjct: 121 CKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLD 180
Query: 181 ICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSL 240
ICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSL
Sbjct: 181 ICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSL 240
Query: 241 SARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLR 300
SARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLR
Sbjct: 241 SARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLR 300
Query: 301 LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRIT 360
LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRIT
Sbjct: 301 LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRIT 360
Query: 361 DMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLA 420
DMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLA
Sbjct: 361 DMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLA 420
Query: 421 LGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE 479
LGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE
Sbjct: 421 LGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE 479
>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
Length = 436
Score = 123 bits (308), Expect = 4e-28
Identities = 109/395 (27%), Positives = 176/395 (44%), Gaps = 31/395 (7%)
Query: 99 EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPV-----LHAKELYNVLP-- 151
+++L +F + C AQV +AW + W + + + + N+
Sbjct: 30 KELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRC 89
Query: 152 GGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRST-ITDAGL 210
GG ++L+G CL GV D + F N + ++ ++L T TDA
Sbjct: 90 GGFLRKLSLRG---------CL-GVGDNALRTFAQNC----RNIEVLNLNGCTKTTDATC 135
Query: 211 EVMLEQMQGVVRLELSGCNDFTEAGL--WSSLSARITSLSVSDCINVADDAIAAISQLLP 268
+ + + L+L+ C T L S + L++S C V D I A+ +
Sbjct: 136 TSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCG 195
Query: 269 NLAELSLQAY-HVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSL 327
L L L+ + D AL Y A TL L +C +IT+ G++ + L +L
Sbjct: 196 GLKALFLKGCTQLEDEALKYIGAHCPELV-TLNLQTCLQITDEGLITICRGCHKLQSLCA 254
Query: 328 SGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITD 387
SGCS +TD + + +N +LR L+++ C ++TD+ +A + H LE++ L+ CV+ITD
Sbjct: 255 SGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITD 314
Query: 388 TGLSYLST-MSSLRSLYLRWCCQVQDFGLKHL----LALGSLRLLSPAGCPLLTTTGLSG 442
+ L LS L+ L L C + D G++HL A L ++ CPL+T L
Sbjct: 315 STLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEH 374
Query: 443 LVQLQELEELELTNCPGATPELFKYFSQHLPRCLV 477
L LE +EL +C T K HLP V
Sbjct: 375 LKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKV 409
Score = 100 bits (250), Expect = 2e-21
Identities = 77/245 (31%), Positives = 116/245 (47%), Gaps = 17/245 (6%)
Query: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSL----QAYHVTDTALAYFTARQGHSTHTL 299
+ LS+ C+ V D+A+ +Q N+ L+L + T T+L+ F ++ H L
Sbjct: 93 LRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRH----L 148
Query: 300 RLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRI 359
L SC ITN + + P L L++S C +VT DG++ + L++L L C ++
Sbjct: 149 DLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQL 208
Query: 360 TDMALEYVACDLHRLEELVLDRCVRITDTGL-SYLSTMSSLRSLYLRWCCQVQDFGLKHL 418
D AL+Y+ L L L C++ITD GL + L+SL C + D L
Sbjct: 209 EDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILN-- 266
Query: 419 LALGS----LRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPELFKYFSQHLP 473
ALG LR+L A C LT G + L + ELE+++L C T S H P
Sbjct: 267 -ALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCP 325
Query: 474 RCLVI 478
R V+
Sbjct: 326 RLQVL 330
Score = 77.4 bits (189), Expect = 3e-14
Identities = 54/192 (28%), Positives = 96/192 (50%), Gaps = 3/192 (1%)
Query: 291 RQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRS 350
R G L L C + ++ + + N+ L+L+GC+K TD +++ KLR
Sbjct: 88 RCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRH 147
Query: 351 LDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYL-STMSSLRSLYLRWCCQ 409
LDL+ C IT+M+L+ ++ LE+L + C ++T G+ L L++L+L+ C Q
Sbjct: 148 LDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQ 207
Query: 410 VQDFGLKHLLA-LGSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPELFKY 467
++D LK++ A L L+ C +T GL + + +L+ L + C T +
Sbjct: 208 LEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNA 267
Query: 468 FSQHLPRCLVIE 479
Q+ PR ++E
Sbjct: 268 LGQNCPRLRILE 279
>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
Length = 418
Score = 121 bits (304), Expect = 1e-27
Identities = 106/384 (27%), Positives = 189/384 (49%), Gaps = 35/384 (9%)
Query: 100 KILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELY-NVLPGGEKEFV 158
++L +F Y +K AQVC AWR Y W G+ LH + ++ P + +
Sbjct: 11 ELLAMIFGYLDVRDKGRAAQVCTAWRDAAYHKSVWRGVEAKLHLRRANPSLFPSLQARGI 70
Query: 159 N-LQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGV-----------KAMSLKR-STI 205
+Q + R + + G+++++ Y L+ G+ +A++L I
Sbjct: 71 RRVQILSLRRSLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQI 130
Query: 206 TDAGLEVMLEQMQGVVRLELSGCNDFTEAGL----WSSLSARITSLSVSDCINVADDAIA 261
TD+ L + + ++G+ LEL GC++ T GL W R+ SL++ C +++D I
Sbjct: 131 TDSSLGRIAQYLKGLEVLELGGCSNITNTGLLLIAWGL--QRLKSLNLRSCRHLSDVGIG 188
Query: 262 AISQLLPNLAE-------LSLQ-AYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVV 313
++ + + AE L+LQ +TD +L + + R L L C I++ G++
Sbjct: 189 HLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKHIS-RGLTGLRLLNLSFCGGISDAGLL 247
Query: 314 NVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHR 373
++ H + +L +L+L C ++D G+ +A +L LD+S+C ++ D +L Y+A L
Sbjct: 248 HLSH-MGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDG 306
Query: 374 LEELVLDRCVRITDTGLS-YLSTMSSLRSLYLRWCCQVQDFGLKHLLA--LGSLRLLSPA 430
L+ L L C I+D G++ + M LR+L + C ++ D GL+ L+A L L +
Sbjct: 307 LKSLSLCSC-HISDDGINRMVRQMHGLRTLNIGQCVRITDKGLE-LIAEHLSQLTGIDLY 364
Query: 431 GCPLLTTTGLSGLVQLQELEELEL 454
GC +T GL + QL L+ L L
Sbjct: 365 GCTRITKRGLERITQLPCLKVLNL 388
Score = 102 bits (253), Expect = 1e-21
Identities = 67/224 (29%), Positives = 116/224 (51%), Gaps = 10/224 (4%)
Query: 259 AIAAISQLLPNLAELSLQA-YHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVH 317
+++ + Q + N+ L+L Y++TD L + ++ S L L C +IT+ + +
Sbjct: 81 SLSYVIQGMANIESLNLSGCYNLTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQ 140
Query: 318 SLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHR---- 373
L L L L GCS +T+ G+ L+A L++L+SL+L C ++D+ + ++A
Sbjct: 141 YLKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEG 200
Query: 374 ---LEELVLDRCVRITDTGLSYLST-MSSLRSLYLRWCCQVQDFGLKHLLALGSLRLLSP 429
LE+L L C ++TD L ++S ++ LR L L +C + D GL HL +GSLR L+
Sbjct: 201 CLGLEQLTLQDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNL 260
Query: 430 AGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPELFKYFSQHL 472
C ++ TG+ L L L+++ C + Y +Q L
Sbjct: 261 RSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGL 304
>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
Length = 491
Score = 107 bits (268), Expect = 2e-23
Identities = 127/475 (26%), Positives = 207/475 (43%), Gaps = 75/475 (15%)
Query: 23 LPGQPNGLGAA----SITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPCTPAG 78
LPG NG G++ SIT T A + P PP L PL R A P
Sbjct: 64 LPGFQNGRGSSTSSSSITGETVAMVHSP---------PPTRLTHPLIRLA-----SRPQK 109
Query: 79 GPASALAPGHPAERPPLATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLT 138
AS +R P D ++ +F + + C A+VC+ W + + P+ W +
Sbjct: 110 EQASI-------DRLP---DHSMVQ-IFSFLPTNQLCRCARVCRRWYNLAWDPRLWRTIR 158
Query: 139 PVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAM 198
L G E +N+ + V +C+ N L + V
Sbjct: 159 -----------LTG---ETINVDR----------ALKVLTRRLCQDTPNVCLMLETVTVS 194
Query: 199 SLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWS--SLSARITSLSVS-----D 251
+R +TD GL + + + RLE+SGC + + ++ SL + L VS
Sbjct: 195 GCRR--LTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVT 252
Query: 252 CINVADDAIAAISQLLPNLAELSLQAYHVT------DTALAYFTARQGHSTHTLRLLSCW 305
CI++ +A +S L + ++S++ +T D L A TH L L C
Sbjct: 253 CISLTREASIKLSPL--HGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTH-LYLRRCV 309
Query: 306 EITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALE 365
+T+ G+ +V ++ LS+S C V+D G+ +A+ +LR L ++ C R+TD+ +
Sbjct: 310 RLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIR 369
Query: 366 YVACDLHRLEELVLDRCVRITDTGLSYLS-TMSSLRSLYLRWCCQVQDFGLKHL-LALGS 423
YVA +L L C ITD G+ YL+ + L+SL + C V D GL+ L L +
Sbjct: 370 YVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFN 429
Query: 424 LRLLSPAGCPLLTTTGLSGL-VQLQELEELELTNCPGATPELFKYFSQHLPRCLV 477
L+ LS C +T GL + +L+ L + +C + E ++ +H RC++
Sbjct: 430 LKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCE-VSVEALRFVKRHCKRCVI 483
>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
Length = 423
Score = 100 bits (250), Expect = 2e-21
Identities = 72/234 (30%), Positives = 108/234 (46%), Gaps = 3/234 (1%)
Query: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLS 303
+ LS+ CI V D ++ +Q N+ L+L + Y +R L L S
Sbjct: 80 LRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTS 139
Query: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
C ITN + + NL L+LS C ++T DG+E + R L++L L C ++ D A
Sbjct: 140 CVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEA 199
Query: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLST-MSSLRSLYLRWCCQVQDFGLKHL-LAL 421
L+++ H L L L C RITD G+ + L++L L C + D L L L
Sbjct: 200 LKHIQNYCHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNC 259
Query: 422 GSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPELFKYFSQHLPR 474
L++L A C LT G + L + ELE+++L C T S H P+
Sbjct: 260 PRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPK 313
Score = 99.8 bits (247), Expect = 5e-21
Identities = 104/419 (24%), Positives = 167/419 (39%), Gaps = 52/419 (12%)
Query: 99 EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFV 158
+++L +F + C AQ+ KAW + W + +L+N E V
Sbjct: 17 KELLLRIFSFLDIVTLCRCAQISKAWNILALDGSNWQRI-------DLFNFQIDVEGRVV 69
Query: 159 N---------LQGFAARGFEGFCLVGVSDLDICEFIDN--------------------YA 189
L+ + RG +GV D + F N Y+
Sbjct: 70 ENISKRCGGFLRKLSLRG-----CIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYS 124
Query: 190 LSKKGVKAMSLKRST---ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA--RI 244
LS+ K L ++ IT++ L+ + E + + L LS C+ T+ G+ + + +
Sbjct: 125 LSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGL 184
Query: 245 TSLSVSDCINVADDAIAAISQLLPNLAELSLQAY-HVTDTALAYFTARQGHSTHTLRLLS 303
+L + C + D+A+ I L L+LQ+ +TD + R H L L
Sbjct: 185 KALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQI-CRGCHRLQALCLSG 243
Query: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
C +T+ + + + P L L + CS +TD G L+A N +L +DL C ITD
Sbjct: 244 CSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEKMDLEECILITDST 303
Query: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMS----SLRSLYLRWCCQVQDFGLKHLL 419
L ++ +L+ L L C ITD G+ +LS + LR L L C + D L+HL
Sbjct: 304 LIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRVLELDNCLLITDVALEHLE 363
Query: 420 ALGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVI 478
L L C +T G+ + ++ P P Q L RC VI
Sbjct: 364 NCRGLERLELYDCQQVTRAGIKRMRAQLPHVKVHAYFAPVTPPTAVAGSGQRLCRCCVI 422
>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
[Homo sapiens]
Length = 735
Score = 87.0 bits (214), Expect = 3e-17
Identities = 82/273 (30%), Positives = 134/273 (49%), Gaps = 22/273 (8%)
Query: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSL----SARITSLSVSDCINVADDAI 260
ITD+ L L ++ + L L+ C + GL L S RI L++S+C+ ++D ++
Sbjct: 439 ITDSSLR-SLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASV 497
Query: 261 AAISQLLPNLAELSLQ-AYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL 319
+S+ PNL LSL+ H+T + Y S ++ L S +I+N G+ NV+
Sbjct: 498 MKLSERCPNLNYLSLRNCEHLTAQGIGYIV--NIFSLVSIDL-SGTDISNEGL-NVLSRH 553
Query: 320 PNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVL 379
L LS+S C ++TDDG++ ++ L LD+S+C +++DM ++ +A L L +
Sbjct: 554 KKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSI 613
Query: 380 DRCVRITDTGLSYLSTMSS-LRSLYLRWCCQVQDFGLKHL-LALGSLRLLSPAGCPLLTT 437
C +ITD+ + LS L L + C + D L+ L + LR+L C ++
Sbjct: 614 AGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISK 673
Query: 438 TG---LSGLVQLQELEELELTNCPGATPELFKY 467
+S VQ QE TN P P F Y
Sbjct: 674 KAAQRMSSKVQQQEYN----TNDP---PRWFGY 699
Score = 70.5 bits (171), Expect = 3e-12
Identities = 70/309 (22%), Positives = 135/309 (43%), Gaps = 39/309 (12%)
Query: 194 GVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLW---------------- 237
GV ++L +TIT+ + ++ + L L+ C FT+ GL
Sbjct: 272 GVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDL 331
Query: 238 --------------SSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQ-AYHVTD 282
++ I L+++D + D+ + A+ + + L A H++D
Sbjct: 332 SGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISD 391
Query: 283 TALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVA 342
F A +R +T+ + + PNL+ + ++ C +TD + ++
Sbjct: 392 CT---FRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS 448
Query: 343 ENLRKLRSLDLSWCPRITDMALEYV--ACDLHRLEELVLDRCVRITDTGLSYLS-TMSSL 399
L++L L+L+ C RI DM L+ R+ EL L CVR++D + LS +L
Sbjct: 449 P-LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNL 507
Query: 400 RSLYLRWCCQVQDFGLKHLLALGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPG 459
L LR C + G+ +++ + SL + +G ++ GL+ L + ++L+EL ++ C
Sbjct: 508 NYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTD-ISNEGLNVLSRHKKLKELSVSECYR 566
Query: 460 ATPELFKYF 468
T + + F
Sbjct: 567 ITDDGIQAF 575
Score = 67.8 bits (164), Expect = 2e-11
Identities = 72/304 (23%), Positives = 119/304 (39%), Gaps = 57/304 (18%)
Query: 220 VVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYH 279
V+RL GC + S + L+VSDC D+++ IS+ P + L+L
Sbjct: 223 VLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTT 282
Query: 280 VTDTALAYFTARQGHSTHTLRLLSCWEITNHGV--VNVVHSLPNLTALSLSGCSKV---- 333
+T+ + R H+ L L C T+ G+ +N+ + L L LSGC+++
Sbjct: 283 ITNRTMRLLP-RHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQG 341
Query: 334 ----------------------TDDGVELVAENLRKLRSLDLSWCP-------------- 357
TD+ V+ + E ++ SL + P
Sbjct: 342 FRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACK 401
Query: 358 ----------RITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWC 407
R+TD + +++ + L + + C ITD+ L LS + L L L C
Sbjct: 402 LRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANC 461
Query: 408 CQVQDFGLKHLL---ALGSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPE 463
++ D GLK L A +R L+ + C L+ + L + L L L NC T +
Sbjct: 462 VRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQ 521
Query: 464 LFKY 467
Y
Sbjct: 522 GIGY 525
>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
[Homo sapiens]
Length = 690
Score = 71.6 bits (174), Expect = 1e-12
Identities = 60/203 (29%), Positives = 100/203 (49%), Gaps = 17/203 (8%)
Query: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSL----SARITSLSVSDCINVADDAI 260
ITD+ L L ++ + L L+ C + GL L S RI L++S+C+ ++D ++
Sbjct: 439 ITDSSLR-SLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASV 497
Query: 261 AAISQLLPNLAELSLQ-AYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL 319
+S+ PNL LSL+ H+T + Y S ++ L S +I+N G+ NV+
Sbjct: 498 MKLSERCPNLNYLSLRNCEHLTAQGIGYIV--NIFSLVSIDL-SGTDISNEGL-NVLSRH 553
Query: 320 PNLTALSLSGCSKVTDDGV-------ELVAENLRKLRSLDLSWCPRITDMALEYVACDLH 372
L LS+S C ++TDDG+ E+++ L LD+S C +TD LE +
Sbjct: 554 KKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCK 613
Query: 373 RLEELVLDRCVRITDTGLSYLST 395
+L L + C I+ +S+
Sbjct: 614 QLRILKMQYCTNISKKAAQRMSS 636
Score = 70.1 bits (170), Expect = 4e-12
Identities = 68/298 (22%), Positives = 131/298 (43%), Gaps = 39/298 (13%)
Query: 194 GVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLW---------------- 237
GV ++L +TIT+ + ++ + L L+ C FT+ GL
Sbjct: 272 GVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDL 331
Query: 238 --------------SSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQ-AYHVTD 282
++ I L+++D + D+ + A+ + + L A H++D
Sbjct: 332 SGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISD 391
Query: 283 TALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVA 342
F A +R +T+ + + PNL+ + ++ C +TD + ++
Sbjct: 392 CT---FRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLS 448
Query: 343 ENLRKLRSLDLSWCPRITDMALEYV--ACDLHRLEELVLDRCVRITDTGLSYLS-TMSSL 399
L++L L+L+ C RI DM L+ R+ EL L CVR++D + LS +L
Sbjct: 449 P-LKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNL 507
Query: 400 RSLYLRWCCQVQDFGLKHLLALGSLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNC 457
L LR C + G+ +++ + SL + +G ++ GL+ L + ++L+EL ++ C
Sbjct: 508 NYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTD-ISNEGLNVLSRHKKLKELSVSEC 564
Score = 67.8 bits (164), Expect = 2e-11
Identities = 72/304 (23%), Positives = 119/304 (39%), Gaps = 57/304 (18%)
Query: 220 VVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYH 279
V+RL GC + S + L+VSDC D+++ IS+ P + L+L
Sbjct: 223 VLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTT 282
Query: 280 VTDTALAYFTARQGHSTHTLRLLSCWEITNHGV--VNVVHSLPNLTALSLSGCSKV---- 333
+T+ + R H+ L L C T+ G+ +N+ + L L LSGC+++
Sbjct: 283 ITNRTMRLLP-RHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQG 341
Query: 334 ----------------------TDDGVELVAENLRKLRSLDLSWCP-------------- 357
TD+ V+ + E ++ SL + P
Sbjct: 342 FRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACK 401
Query: 358 ----------RITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWC 407
R+TD + +++ + L + + C ITD+ L LS + L L L C
Sbjct: 402 LRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANC 461
Query: 408 CQVQDFGLKHLL---ALGSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNCPGATPE 463
++ D GLK L A +R L+ + C L+ + L + L L L NC T +
Sbjct: 462 VRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQ 521
Query: 464 LFKY 467
Y
Sbjct: 522 GIGY 525
Score = 60.8 bits (146), Expect = 3e-09
Identities = 69/288 (23%), Positives = 122/288 (42%), Gaps = 54/288 (18%)
Query: 175 GVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEA 234
G + C F A + ++ KR +TDA + + + + + ++ C T++
Sbjct: 385 GAPHISDCTFRALSACKLRKIRFEGNKR--VTDASFKFIDKNYPNLSHIYMADCKGITDS 442
Query: 235 GLWS-SLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQG 293
L S S ++T L++++C+ + D + Q L A + ++
Sbjct: 443 SLRSLSPLKQLTVLNLANCVRIGD---MGLKQFLDGPASMRIRE---------------- 483
Query: 294 HSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDL 353
L L +C +++ V+ + PNL LSL C +T G+ + N+ L S+DL
Sbjct: 484 -----LNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIV-NIFSLVSIDL 537
Query: 354 SWCPRITDMALE--YVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQ 411
S TD++ E V +L+EL + C RITD G+ Q+
Sbjct: 538 SG----TDISNEGLNVLSRHKKLKELSVSECYRITDDGI------------------QIT 575
Query: 412 DFGLKHLLA-LGSLRLLSPAGCPLLTTTGLSGL-VQLQELEELELTNC 457
D ++ L A L +L +GC LLT L L + ++L L++ C
Sbjct: 576 DSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYC 623
>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
sapiens]
Length = 300
Score = 60.8 bits (146), Expect = 3e-09
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 3/163 (1%)
Query: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA--RITSLSVSDCINVADDAIAA 262
++D L +L + + + L GC + L + R+ LS++ C V A+
Sbjct: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160
Query: 263 ISQLLPNLAELSLQAYH-VTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPN 321
++ P L EL L A + D A+ Y R+G +L L + + V + + P
Sbjct: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE 220
Query: 322 LTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMAL 364
L L L+GC +V DGV +AE LRSL + C + + +L
Sbjct: 221 LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSL 263
Score = 54.3 bits (129), Expect = 2e-07
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 5/172 (2%)
Query: 291 RQGHSTHTLRLLSCWE-ITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLR 349
R L L C E +++ +V V+ P L +++L GC +++ + +AE +L+
Sbjct: 84 RDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQ 143
Query: 350 SLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTM--SSLRSLYLRWC 407
L L+ C + +AL +A LEEL L C ++ D + YL+ + LRSL L
Sbjct: 144 RLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVN 203
Query: 408 CQVQDFGLKHLLA-LGSLRLLSPAGCPLLTTTGLSGLVQ-LQELEELELTNC 457
V D ++ L L L GC + + G+ L + L L + +C
Sbjct: 204 ANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHC 255
Score = 50.4 bits (119), Expect = 3e-06
Identities = 47/193 (24%), Positives = 87/193 (45%), Gaps = 4/193 (2%)
Query: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSAR---ITSLSVSDCINVADDAIA 261
I A L +L +G+ L L+ C+++ + AR + S+++ C ++ A+
Sbjct: 74 IPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALG 133
Query: 262 AISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL-P 320
A+++ P L LSL D A + + L L +C ++ + +V +
Sbjct: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGA 193
Query: 321 NLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLD 380
L +LSL+ + V D V+ +A N +L LDL+ C R+ + +A L L +
Sbjct: 194 GLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVR 253
Query: 381 RCVRITDTGLSYL 393
C + ++ LS L
Sbjct: 254 HCHHVAESSLSRL 266
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/162 (31%), Positives = 72/162 (44%), Gaps = 8/162 (4%)
Query: 314 NVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHR 373
+V++ +P L L S+ V+L LR+ + + P+I AL + D
Sbjct: 31 HVLNRVPLRQLLRLQRVSRAFRSLVQLHLAGLRRFDAAQVG--PQIPRAALARLLRDAEG 88
Query: 374 LEELVLDRCVR-ITDTGL-SYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRL--LSP 429
L+EL L C ++D L L+ LRS+ L C Q+ L LA G RL LS
Sbjct: 89 LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALG-ALAEGCPRLQRLSL 147
Query: 430 AGCPLLTTTGLSGLV-QLQELEELELTNCPGATPELFKYFSQ 470
A C + L GL + LEEL+LT C E Y +Q
Sbjct: 148 AHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQ 189
>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
sapiens]
Length = 1336
Score = 59.7 bits (143), Expect = 6e-09
Identities = 84/384 (21%), Positives = 142/384 (36%), Gaps = 98/384 (25%)
Query: 49 PPPPPTLPPPSLAAP----LSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNG 104
PP + PPPS++ P + R + P +P P +L A ++
Sbjct: 1019 PPRVISRPPPSVSPPKCIQMERHVIRPPPISP---PPDSLPLDDGAAH---VMHREVWMA 1072
Query: 105 LFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFA 164
+F Y S + CV +VC+ W R + W +
Sbjct: 1073 VFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRI--------------------------- 1105
Query: 165 ARGFEGFCLVGVSDLDICEFIDNYALS---KKGVKAMSLKRSTITDAGLEVMLEQMQGVV 221
DL+ C+ I LS ++ ++ L + I+ L ++ ++ G+
Sbjct: 1106 -------------DLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLR 1152
Query: 222 RLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVT 281
L LSGC+ W ++SA L S C P L L +Q
Sbjct: 1153 DLVLSGCS-------WIAVSA----LCSSSC---------------PLLRTLDVQWV--- 1183
Query: 282 DTALAYFTARQGHSTHTLR-LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVEL 340
+G +R LLS G ++ L N+ L L+G +TD + L
Sbjct: 1184 ----------EGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRL 1232
Query: 341 VAENLRKLRSLDLSWCPRITDMALEYVAC----DLHRLEELVLDRCVRITDTGLSYLSTM 396
+ ++ L L LS+C +TD ++ + L E+ L C ++TD LS+
Sbjct: 1233 IIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRC 1292
Query: 397 SSLRSLYLRWCCQVQDFGLKHLLA 420
++ + LR+C QV G + +A
Sbjct: 1293 GNICHIDLRYCKQVTKEGCEQFIA 1316
>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
sapiens]
Length = 1265
Score = 59.7 bits (143), Expect = 6e-09
Identities = 84/384 (21%), Positives = 142/384 (36%), Gaps = 98/384 (25%)
Query: 49 PPPPPTLPPPSLAAP----LSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNG 104
PP + PPPS++ P + R + P +P P +L A ++
Sbjct: 950 PPRVISRPPPSVSPPKCIQMERHVIRPPPISP---PPDSLPLDDGAAH---VMHREVWMA 1003
Query: 105 LFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFA 164
+F Y S + CV +VC+ W R + W +
Sbjct: 1004 VFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRI--------------------------- 1036
Query: 165 ARGFEGFCLVGVSDLDICEFIDNYALS---KKGVKAMSLKRSTITDAGLEVMLEQMQGVV 221
DL+ C+ I LS ++ ++ L + I+ L ++ ++ G+
Sbjct: 1037 -------------DLNHCKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLR 1083
Query: 222 RLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVT 281
L LSGC+ W ++SA L S C P L L +Q
Sbjct: 1084 DLVLSGCS-------WIAVSA----LCSSSC---------------PLLRTLDVQWV--- 1114
Query: 282 DTALAYFTARQGHSTHTLR-LLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVEL 340
+G +R LLS G ++ L N+ L L+G +TD + L
Sbjct: 1115 ----------EGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLD-ITDASLRL 1163
Query: 341 VAENLRKLRSLDLSWCPRITDMALEYVAC----DLHRLEELVLDRCVRITDTGLSYLSTM 396
+ ++ L L LS+C +TD ++ + L E+ L C ++TD LS+
Sbjct: 1164 IIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQCLSFFKRC 1223
Query: 397 SSLRSLYLRWCCQVQDFGLKHLLA 420
++ + LR+C QV G + +A
Sbjct: 1224 GNICHIDLRYCKQVTKEGCEQFIA 1247
>gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
sapiens]
Length = 303
Score = 59.3 bits (142), Expect = 7e-09
Identities = 53/218 (24%), Positives = 104/218 (47%), Gaps = 6/218 (2%)
Query: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA--RITSLSVSDCINVADDAIAA 262
+TD GL+ + + + + + C ++ G+ ++ + + + V D ++ A
Sbjct: 53 LTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKA 112
Query: 263 ISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNL 322
++ P L + VT + + T + S+ LR ++ E+ N V+ +V NL
Sbjct: 113 FAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHIT--ELDNETVMEIVKRCKNL 170
Query: 323 TALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRC 382
++L+L + D VE++A+ + L+ L L C +ITD AL + +E + + C
Sbjct: 171 SSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWC 229
Query: 383 VRITDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHLL 419
ITD G + ++ S SLR L L C +V + ++ L+
Sbjct: 230 KEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLV 267
Score = 58.2 bits (139), Expect = 2e-08
Identities = 37/181 (20%), Positives = 84/181 (46%), Gaps = 2/181 (1%)
Query: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAIS 264
+TD ++ E + + GC+ ++ + + ++SL + + ++ + I
Sbjct: 105 VTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIV 164
Query: 265 QLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTA 324
+ NL+ L+L + + A++G + L L+SC +IT++ ++ + +
Sbjct: 165 KRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIET 223
Query: 325 LSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDL-HRLEELVLDRCV 383
+ + C ++TD G L+A++ + LR L L C ++ ++ +E + H VL C
Sbjct: 224 VDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCK 283
Query: 384 R 384
R
Sbjct: 284 R 284
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/150 (21%), Positives = 72/150 (48%), Gaps = 3/150 (2%)
Query: 307 ITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEY 366
++++GV + P L + C +++D + VA + L+ + + ++TD L+
Sbjct: 1 MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
Query: 367 VACDLHRLEELVLDRCVRITDTGLSYLST-MSSLRSLYLRWCCQVQDFGLKHLLA-LGSL 424
+ L+++ +C +I+D G+ ++ L+ +Y++ V D +K L
Sbjct: 61 LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
Query: 425 RLLSPAGCPLLTTTGLSGLVQLQELEELEL 454
+ + GC +T+ G+ L +L+ L L+L
Sbjct: 121 QYVGFMGCS-VTSKGVIHLTKLRNLSSLDL 149
Score = 40.8 bits (94), Expect = 0.003
Identities = 25/124 (20%), Positives = 54/124 (43%)
Query: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
C ++++ ++ V P L + + K+TD+G++ + R+L+ + C +I+D
Sbjct: 24 CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
Query: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGS 423
+ +A +L+ + + +TD + + C V G+ HL L +
Sbjct: 84 MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRN 143
Query: 424 LRLL 427
L L
Sbjct: 144 LSSL 147
>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
sapiens]
Length = 258
Score = 57.0 bits (136), Expect = 4e-08
Identities = 51/191 (26%), Positives = 92/191 (48%), Gaps = 8/191 (4%)
Query: 263 ISQLL-PNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLL--SCWEITNHGVVNVVHSL 319
IS++L P + L L++ ++D AL + + + L + +T+ G+ V S
Sbjct: 55 ISEILHPEVQTLDLRSCDISDAALLHLSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSC 114
Query: 320 PNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVL 379
L SL C +TD+GV +A N + L+ +DL C ITD++L + + L + V
Sbjct: 115 SYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFL-QCVD 173
Query: 380 DRCVRITDTGLSYLST---MSSLRSLYLRWCCQVQDFGLKHLLA-LGSLRLLSPAGCPLL 435
+++D+G+ L + L +++ C + D ++ +L +R+L GCPL+
Sbjct: 174 FSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLI 233
Query: 436 TTTGLSGLVQL 446
T L QL
Sbjct: 234 TDHSREVLEQL 244
Score = 45.8 bits (107), Expect = 9e-05
Identities = 34/183 (18%), Positives = 80/183 (43%), Gaps = 3/183 (1%)
Query: 176 VSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAG 235
+SD + + L K + A R ++T G++ + + L C + T+ G
Sbjct: 73 ISDAALLHLSNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCNLTDEG 132
Query: 236 LWS-SLSARITSL-SVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTA-LAYFTARQ 292
+ + +L+ ++ + + C+++ D ++ A+ + P L + A V+D+ +A +
Sbjct: 133 VVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFSATQVSDSGVIALVSGPC 192
Query: 293 GHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLD 352
+ + C +T+ V V+ P + L GC +TD E++ + + +
Sbjct: 193 AKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVLEQLVGPNKLKQ 252
Query: 353 LSW 355
++W
Sbjct: 253 VTW 255
>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
sapiens]
Length = 694
Score = 53.5 bits (127), Expect = 4e-07
Identities = 81/361 (22%), Positives = 128/361 (35%), Gaps = 88/361 (24%)
Query: 46 PCQPPPPPTL------PPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLATDE 99
P PP PP L PPP P + AG HP R
Sbjct: 388 PAPPPRPPQLERHVVRPPPRSPEPDTLPLAAGSD--------------HPLPRAAWLR-- 431
Query: 100 KILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVN 159
+F + E C+ +VC+ W R Y + W P + ++ P
Sbjct: 432 -----VFQHLGPRELCICMRVCRTWSRWCYDKRLW----PRMDLSRRKSLTPP------- 475
Query: 160 LQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQG 219
L GV ++ +A+ L + ++ L +L ++QG
Sbjct: 476 ------------MLSGVV--------------RRQPRALDLSWTGVSKKQLMWLLNRLQG 509
Query: 220 VVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYH 279
+ L LSGC+ + + L S+ + L + +V D + + LLP
Sbjct: 510 LQELVLSGCSWLSVSALGSAPLPALRLLDLRWIEDVKDSQLREL--LLPP---------- 557
Query: 280 VTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVE 339
DT +R L+ E+T+ + ++ P L+AL LS C+ V D V
Sbjct: 558 -PDTKPGQTESRGRLQGVAELRLAGLELTDASLRLLLRHAPQLSALDLSHCAHVGDPSVH 616
Query: 340 LVAENLRKLRS----LDLSWCPRITDMALE-YVAC------DLHRLEELVLDRCVRITDT 388
L+ LR L+L+ C R+TD L + C DL +L + C R+
Sbjct: 617 LLTAPTSPLRETLVHLNLAGCHRLTDHCLPLFRRCPRLRRLDLRSCRQLSPEACARLAAA 676
Query: 389 G 389
G
Sbjct: 677 G 677
Score = 38.1 bits (87), Expect = 0.018
Identities = 27/74 (36%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
Query: 346 RKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLR 405
R+ R+LDLSW ++ L ++ L L+ELVL C ++ + L + + +LR L LR
Sbjct: 483 RQPRALDLSWTG-VSKKQLMWLLNRLQGLQELVLSGCSWLSVSALGS-APLPALRLLDLR 540
Query: 406 WCCQVQDFGLKHLL 419
W V+D L+ LL
Sbjct: 541 WIEDVKDSQLRELL 554
Score = 35.0 bits (79), Expect = 0.15
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 25/183 (13%)
Query: 302 LSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITD 361
LS ++ ++ +++ L L L LSGCS ++ L + L LR LDL W + D
Sbjct: 490 LSWTGVSKKQLMWLLNRLQGLQELVLSGCSWLSVSA--LGSAPLPALRLLDLRWIEDVKD 547
Query: 362 MALEYVACD--------------LHRLEELVLDRCVRITDTGLSYLSTMS-SLRSLYLRW 406
L + L + EL L + +TD L L + L +L L
Sbjct: 548 SQLRELLLPPPDTKPGQTESRGRLQGVAELRLAG-LELTDASLRLLLRHAPQLSALDLSH 606
Query: 407 CCQVQDFGLKHLLALGSLRL------LSPAGCPLLTTTGLSGLVQLQELEELELTNCPGA 460
C V D + HLL + L L+ AGC LT L + L L+L +C
Sbjct: 607 CAHVGDPSV-HLLTAPTSPLRETLVHLNLAGCHRLTDHCLPLFRRCPRLRRLDLRSCRQL 665
Query: 461 TPE 463
+PE
Sbjct: 666 SPE 668
Score = 30.0 bits (66), Expect = 4.8
Identities = 30/93 (32%), Positives = 33/93 (35%), Gaps = 26/93 (27%)
Query: 28 NGLGAASITKGTPATKNRPCQPPPP------PTLPPP-SLAAPLSRAALAGG--PCTP-- 76
NG AS+ G T+ P PPPP P PPP + P R G P TP
Sbjct: 169 NGEEGASLGSGWKLTEEPPLPPPPPRRKGPLPAGPPPEDVPGPPKRKEREAGNEPPTPRK 228
Query: 77 ------------AGGPASALA---PGHPAERPP 94
GG A L PG P PP
Sbjct: 229 KVKGGRERHLKKVGGDACLLRGSDPGGPGLLPP 261
>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
Length = 223
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/122 (30%), Positives = 61/122 (50%), Gaps = 3/122 (2%)
Query: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAY-HVTDTALAYFTARQGHSTHTLRLL 302
+ L ++ C + D ++A + Q L L +LSL +TD L AR S L L
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVA-VARGCPSLEHLALS 134
Query: 303 SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDM 362
C +++ G S P L L+LS CS++ + ++ + + R+LR LD++ CP I
Sbjct: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMA 194
Query: 363 AL 364
A+
Sbjct: 195 AV 196
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/167 (29%), Positives = 73/167 (43%), Gaps = 16/167 (9%)
Query: 252 CINVADDAIAAIS----QLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLL----- 302
C++ A +A++S L + EL QA D QG S TLR L
Sbjct: 27 CMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDAC----PEPQGPSLLTLRALQELDL 82
Query: 303 -SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITD 361
+C ++T+ + V+ L L LSLS ++TD+G+ VA L L LS C R++D
Sbjct: 83 TACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSD 141
Query: 362 MALEYVACDLHRLEELVLDRCVRITDTGLSYL-STMSSLRSLYLRWC 407
A RL+ L L C ++ + L + LR L + C
Sbjct: 142 KGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
Score = 37.0 bits (84), Expect = 0.040
Identities = 49/193 (25%), Positives = 71/193 (36%), Gaps = 39/193 (20%)
Query: 316 VHSLPN-LTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRL 374
+H P+ L +LSL+ CS + L S CP +L L L
Sbjct: 28 MHGAPSQLASLSLAHCSSLKS------RPELEHQASGTKDACPEPQGPSL----LTLRAL 77
Query: 375 EELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHL---------LALGSLR 425
+EL L C ++TD L+ + LR L L ++ D GL + LAL
Sbjct: 78 QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
Query: 426 LLSPAG-------CPLLTTTGLSGLVQL------------QELEELELTNCPGATPELFK 466
LS G P L LS QL ++L L++ CPG +
Sbjct: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVR 197
Query: 467 YFSQHLPRCLVIE 479
F LP+ ++
Sbjct: 198 RFQAQLPQVSCVQ 210
>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
Length = 223
Score = 53.5 bits (127), Expect = 4e-07
Identities = 37/122 (30%), Positives = 61/122 (50%), Gaps = 3/122 (2%)
Query: 244 ITSLSVSDCINVADDAIAAISQLLPNLAELSLQAY-HVTDTALAYFTARQGHSTHTLRLL 302
+ L ++ C + D ++A + Q L L +LSL +TD L AR S L L
Sbjct: 77 LQELDLTACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVA-VARGCPSLEHLALS 134
Query: 303 SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDM 362
C +++ G S P L L+LS CS++ + ++ + + R+LR LD++ CP I
Sbjct: 135 HCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMA 194
Query: 363 AL 364
A+
Sbjct: 195 AV 196
Score = 48.1 bits (113), Expect = 2e-05
Identities = 49/167 (29%), Positives = 73/167 (43%), Gaps = 16/167 (9%)
Query: 252 CINVADDAIAAIS----QLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLL----- 302
C++ A +A++S L + EL QA D QG S TLR L
Sbjct: 27 CMHGAPSQLASLSLAHCSSLKSRPELEHQASGTKDAC----PEPQGPSLLTLRALQELDL 82
Query: 303 -SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITD 361
+C ++T+ + V+ L L LSLS ++TD+G+ VA L L LS C R++D
Sbjct: 83 TACSKLTDASLAKVLQFL-QLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSD 141
Query: 362 MALEYVACDLHRLEELVLDRCVRITDTGLSYL-STMSSLRSLYLRWC 407
A RL+ L L C ++ + L + LR L + C
Sbjct: 142 KGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188
Score = 37.0 bits (84), Expect = 0.040
Identities = 49/193 (25%), Positives = 71/193 (36%), Gaps = 39/193 (20%)
Query: 316 VHSLPN-LTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRL 374
+H P+ L +LSL+ CS + L S CP +L L L
Sbjct: 28 MHGAPSQLASLSLAHCSSLKS------RPELEHQASGTKDACPEPQGPSL----LTLRAL 77
Query: 375 EELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHL---------LALGSLR 425
+EL L C ++TD L+ + LR L L ++ D GL + LAL
Sbjct: 78 QELDLTACSKLTDASLAKVLQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSHCS 137
Query: 426 LLSPAG-------CPLLTTTGLSGLVQL------------QELEELELTNCPGATPELFK 466
LS G P L LS QL ++L L++ CPG +
Sbjct: 138 RLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATCPGINMAAVR 197
Query: 467 YFSQHLPRCLVIE 479
F LP+ ++
Sbjct: 198 RFQAQLPQVSCVQ 210
>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
Length = 621
Score = 52.4 bits (124), Expect = 9e-07
Identities = 62/222 (27%), Positives = 96/222 (43%), Gaps = 12/222 (5%)
Query: 220 VVRLELSGCNDF---TEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQ 276
+VRLELS C+ F T + S + + +L++S C + A I++L +L L L
Sbjct: 377 LVRLELS-CSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLC-SLKRLVLY 434
Query: 277 AYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVN--VVHSLPNLTALSLSGCSKVT 334
V TAL H L L SC I ++ V+ + L L L C +T
Sbjct: 435 RTKVEQTALLSILNFCSELQH-LSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNIT 493
Query: 335 DDGVELVAENLRKLRSLDLSWCPRITDM--ALEYVACDLHRLEELVLDRCVRITDTGLSY 392
++G+ +A L LDL WCP + +A L L++L L + DT +
Sbjct: 494 ENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTANRSVCDTDIDE 553
Query: 393 LS-TMSSLRSLYLRWCCQVQDFGLKHLL-ALGSLRLLSPAGC 432
L+ + L+ L + V L+ LL + L LL + C
Sbjct: 554 LACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFC 595
Score = 38.1 bits (87), Expect = 0.018
Identities = 42/212 (19%), Positives = 81/212 (38%), Gaps = 28/212 (13%)
Query: 187 NYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA---- 242
N+ +K + L R+ + L +L + L L C + + +S+
Sbjct: 420 NHIAKLCSLKRLVLYRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCK 479
Query: 243 RITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLL 302
++ +L + C N+ ++ IA ++ P L EL L ++ FT
Sbjct: 480 KLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFT------------- 526
Query: 303 SCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDM 362
+ H LPNL L L+ V D ++ +A N +L+ LD+ ++
Sbjct: 527 -----------RLAHQLPNLQKLFLTANRSVCDTDIDELACNCTRLQQLDILGTRMVSPA 575
Query: 363 ALEYVACDLHRLEELVLDRCVRITDTGLSYLS 394
+L + L L + C +I + + L+
Sbjct: 576 SLRKLLESCKDLSLLDVSFCSQIDNRAVLELN 607
>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
Length = 1162
Score = 51.6 bits (122), Expect = 2e-06
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 93/335 (27%)
Query: 105 LFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFA 164
+F Y S E C +VCK W + + W +
Sbjct: 901 VFRYLSRRELCECMRVCKTWYKWCCDKRLWTKI--------------------------- 933
Query: 165 ARGFEGFCLVGVSDLDICEFIDNYALS---KKGVKAMSLKRSTITDAGLEVMLEQMQGVV 221
DL C+ I ALS K+ ++ L + I+ L ++ ++ G+
Sbjct: 934 -------------DLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLK 980
Query: 222 RLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQ-AYHV 280
L L+GC+ WS++SA LS S C P L L L+ A +
Sbjct: 981 DLLLAGCS-------WSAVSA----LSTSSC---------------PLLRTLDLRWAVGI 1014
Query: 281 TDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVEL 340
D + R L G N L N+T L+G +TD + L
Sbjct: 1015 KDPQI--------------RDLLTPPADKPGQDNR-SKLRNMTDFRLAGLD-ITDATLRL 1058
Query: 341 VAENLRKLRSLDLSWCPRITDMALEYVAC----DLHRLEELVLDRCVRITDTGLSYLSTM 396
+ ++ L LDLS C +TD + + + L EL + C ++TD L YL +
Sbjct: 1059 IIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRI 1118
Query: 397 SSLRSLYLRWCCQVQDFGLKHL---LALGSLRLLS 428
+++ + LR C Q+ +H L++ SL LS
Sbjct: 1119 ANVTLIDLRGCKQITRKACEHFISDLSINSLYCLS 1153
>gi|8922303 ATP5S-like [Homo sapiens]
Length = 257
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/93 (37%), Positives = 51/93 (54%), Gaps = 3/93 (3%)
Query: 389 GLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALG-SLRLLSPAGCPLLTTTGLSGLVQLQ 447
GL L + L+SL L+ C V D+ L L L SL+ LS AGCP ++ GL+ L LQ
Sbjct: 140 GLDNLLRLKELQSLSLQRCSHVDDWCLSRLYPLADSLQELSLAGCPRISERGLACLHHLQ 199
Query: 448 ELEELELTNCPG-ATPELFKYF-SQHLPRCLVI 478
L L++++ P + P L + + LP C V+
Sbjct: 200 NLRRLDISDLPAVSNPGLTQILVEEMLPNCEVV 232
Score = 38.5 bits (88), Expect = 0.014
Identities = 25/75 (33%), Positives = 39/75 (52%)
Query: 345 LRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYL 404
L++L+SL L C + D L + L+EL L C RI++ GL+ L + +LR L +
Sbjct: 147 LKELQSLSLQRCSHVDDWCLSRLYPLADSLQELSLAGCPRISERGLACLHHLQNLRRLDI 206
Query: 405 RWCCQVQDFGLKHLL 419
V + GL +L
Sbjct: 207 SDLPAVSNPGLTQIL 221
Score = 33.5 bits (75), Expect = 0.44
Identities = 26/116 (22%), Positives = 52/116 (44%), Gaps = 4/116 (3%)
Query: 255 VADDAIAAISQLLPNLAELSLQAYHVTDTALAYF---TARQGHSTHTLRLLSCWEITNHG 311
+ D SQ N E+ ++A D + Y + +L L C + +
Sbjct: 106 IRPDKYGHFSQEFWNFCEVPVEAVDAGDCDINYEGLDNLLRLKELQSLSLQRCSHVDDWC 165
Query: 312 VVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYV 367
+ + +L LSL+GC ++++ G+ + +L+ LR LD+S P +++ L +
Sbjct: 166 LSRLYPLADSLQELSLAGCPRISERGLACL-HHLQNLRRLDISDLPAVSNPGLTQI 220
>gi|38348406 leucine rich repeat containing 33 [Homo sapiens]
Length = 692
Score = 47.0 bits (110), Expect = 4e-05
Identities = 61/212 (28%), Positives = 91/212 (42%), Gaps = 19/212 (8%)
Query: 218 QGVVRLE--LSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAIAAISQLLPNLAEL 273
QGV +L + C + A + SSL AR+ +L + + + ++ Q P L L
Sbjct: 31 QGVCKLVGGAADCRGQSLASVPSSLPPHARMLTLDANPLKTLWNHSL----QPYPLLESL 86
Query: 274 SLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKV 333
SL + H+ + F QGH + +C +H+LP L L LSG + +
Sbjct: 87 SLHSCHLERISRGAFQ-EQGHLRSLVLGDNCLSENYEETAAALHALPGLRRLDLSG-NAL 144
Query: 334 TDDGVELVAENLRKLRSLDL--SWCPRITDMALEYVACDLHRLEELVLDR--CVRITDTG 389
T+D L+ +NL LRS+ L + R+ D E L RL EL L R I
Sbjct: 145 TEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFE----GLERLRELDLQRNYIFEIEGGA 200
Query: 390 LSYLSTMSSLRSLYLRWCCQVQDFGLKHLLAL 421
L+ + L + C + DFGL L L
Sbjct: 201 FDGLAELRHLNLAFNNLPC-IVDFGLTRLRVL 231
>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
sapiens]
Length = 533
Score = 46.6 bits (109), Expect = 5e-05
Identities = 99/395 (25%), Positives = 143/395 (36%), Gaps = 75/395 (18%)
Query: 41 ATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHP-AERPPLATDE 99
A++ P QPP P+ A S AA A P PA P P +R PL
Sbjct: 63 ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPA-PAPTPTPEEGPDAGWGDRIPL---- 117
Query: 100 KILNGLFWYFSACEKCV-----LAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGE 154
+IL +F A + + A+VC+ W+ QP W H L + L G
Sbjct: 118 EILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW-------HTVTLSSPLVGRP 170
Query: 155 KEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLE-VM 213
+K GVKA ++ + A LE +M
Sbjct: 171 ------------------------------------AKGGVKA---EKKLL--ASLEWLM 189
Query: 214 LEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAEL 273
+ + RL L ++ L R+T L +S C V DA+ +++ L L
Sbjct: 190 PNRFSQLQRLTLI----HWKSQLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSL 245
Query: 274 SLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKV 333
LQ V TA+ F G L L + T + P L L +S
Sbjct: 246 DLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINR 305
Query: 334 TDDGVELVAENLRK-------LRSLDLSWCPRITDMALEYVACDLHRLEELVL--DRCVR 384
++L E L+K LR L+L W P+ + LEEL L C
Sbjct: 306 NSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVA-PGPGFPSLEELCLASSTCNF 364
Query: 385 ITDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHL 418
+++ L L S +LR L LR C ++ GL+ L
Sbjct: 365 VSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL 399
Score = 37.0 bits (84), Expect = 0.040
Identities = 36/133 (27%), Positives = 57/133 (42%), Gaps = 17/133 (12%)
Query: 320 PNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVL 379
P LT L LSGC VT D + ++A+ +L SLD L++ + + +
Sbjct: 214 PRLTFLKLSGCHGVTADALVMLAKACCQLHSLD-----------LQHSMVESTAVVSFLE 262
Query: 380 DRCVRITDTGLSYLSTMSSLRSLYLRWCC-QVQDFGLKHLLALGSLRLLSPA-----GCP 433
+ R+ L+Y S +++ L CC Q+Q + + S+ L P GCP
Sbjct: 263 EAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCP 322
Query: 434 LLTTTGLSGLVQL 446
L L L+ L
Sbjct: 323 QLQVLRLLNLMWL 335
Score = 35.0 bits (79), Expect = 0.15
Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)
Query: 320 PNLTALSL--SGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEEL 377
P+L L L S C+ V+++ + + LR LDL C RIT L+ + C LE+L
Sbjct: 350 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPC--RELEQL 407
Query: 378 VLDRCVRITDTGLSYLSTMSSLRSLYL--RWCCQV-------QDFGLKHLLALGSLRLLS 428
L G S T++ S +L +WC + Q F K L + L +
Sbjct: 408 HLGL------YGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLST 461
Query: 429 PAGC-PLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCL 476
P G P L + L G +++CPG Y + RCL
Sbjct: 462 PGGSHPALCSLNLRGTRVTPSTVSSVISSCPG-----LLYLNLESCRCL 505
>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
sapiens]
Length = 410
Score = 46.2 bits (108), Expect = 7e-05
Identities = 63/275 (22%), Positives = 114/275 (41%), Gaps = 18/275 (6%)
Query: 99 EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPV---LHAKELYNVLPGGEK 155
+++L G+F E ++ VCK W R+ W L LH +L G
Sbjct: 102 DELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVI 161
Query: 156 EFVNLQGFAARGF-EGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVM- 213
F + F + E F V +D+ + + + G+ + K ++ GL +
Sbjct: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS-TLHGILSQCSKLQNLSLEGLRLSD 220
Query: 214 -----LEQMQGVVRLELSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAI-AAISQ 265
L + +VRL LSGC+ F+E L + LS +R+ L++S C + + + A++
Sbjct: 221 PIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAH 280
Query: 266 LLPNLAELSLQAY--HVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLT 323
+ + +L+L Y ++ + L+ R + H LS + + L L
Sbjct: 281 VSETITQLNLSGYRKNLQKSDLSTLVRRCPNLVHL--DLSDSVMLKNDCFQEFFQLNYLQ 338
Query: 324 ALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPR 358
LSLS C + + + LV ++R CP+
Sbjct: 339 HLSLSRCYDIIPETLLLVTRAGVRIRLDSDIGCPQ 373
Score = 38.1 bits (87), Expect = 0.018
Identities = 44/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 308 TNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYV 367
T HG+++ L NL SL G +++D V +A+N +R L+LS C ++ AL+ +
Sbjct: 197 TLHGILSQCSKLQNL---SLEGL-RLSDPIVNTLAKNSNLVR-LNLSGCSGFSEFALQTL 251
Query: 368 ACDLHRLEELVLDRCVRITD----TGLSYLS-TMSSLRSLYLRWCCQVQDFGLKHLLALG 422
RL+EL L C T+ ++++S T++ L R Q D +
Sbjct: 252 LSSCSRLDELNLSWCFDFTEKHVQVAVAHVSETITQLNLSGYRKNLQKSDLSTL-VRRCP 310
Query: 423 SLRLLSPAGCPLLTTTGLSGLVQLQELEELELTNCPGATPE 463
+L L + +L QL L+ L L+ C PE
Sbjct: 311 NLVHLDLSDSVMLKNDCFQEFFQLNYLQHLSLSRCYDIIPE 351
>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
sapiens]
Length = 539
Score = 45.8 bits (107), Expect = 9e-05
Identities = 98/394 (24%), Positives = 142/394 (36%), Gaps = 67/394 (17%)
Query: 41 ATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHP-AERPPLATDE 99
A++ P QPP P+ A S AA A P PA P P +R PL
Sbjct: 63 ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPA-PAPTPTPEEGPDAGWGDRIPL---- 117
Query: 100 KILNGLFWYFSACEKCV-----LAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGE 154
+IL +F A + + A+VC+ W+ QP W T L + + GG
Sbjct: 118 EILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH--TVTLSSPLVGRPAKGGV 175
Query: 155 KEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVML 214
K L L E++ S+ L+R T+
Sbjct: 176 KAEKKL------------------LASLEWLMPNRFSQ-------LQRLTLIH-----WK 205
Query: 215 EQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELS 274
Q+ V++L C R+T L +S C V DA+ +++ L L
Sbjct: 206 SQVHPVLKLVGECC-------------PRLTFLKLSGCHGVTADALVMLAKACCQLHSLD 252
Query: 275 LQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVT 334
LQ V TA+ F G L L + T + P L L +S
Sbjct: 253 LQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRN 312
Query: 335 DDGVELVAENLRK-------LRSLDLSWCPRITDMALEYVACDLHRLEELVL--DRCVRI 385
++L E L+K LR L+L W P+ + LEEL L C +
Sbjct: 313 SIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVA-PGPGFPSLEELCLASSTCNFV 371
Query: 386 TDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHL 418
++ L L S +LR L LR C ++ GL+ L
Sbjct: 372 SNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL 405
Score = 40.0 bits (92), Expect = 0.005
Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 18/149 (12%)
Query: 305 WEITNHGVVNVV-HSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363
W+ H V+ +V P LT L LSGC VT D + ++A+ +L SLD
Sbjct: 204 WKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLD----------- 252
Query: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCC-QVQDFGLKHLLALG 422
L++ + + + + R+ L+Y S +++ L CC Q+Q + +
Sbjct: 253 LQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRN 312
Query: 423 SLRLLSPA-----GCPLLTTTGLSGLVQL 446
S+ L P GCP L L L+ L
Sbjct: 313 SIPLQLPVEALQKGCPQLQVLRLLNLMWL 341
Score = 35.0 bits (79), Expect = 0.15
Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)
Query: 320 PNLTALSL--SGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEEL 377
P+L L L S C+ V+++ + + LR LDL C RIT L+ + C LE+L
Sbjct: 356 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPC--RELEQL 413
Query: 378 VLDRCVRITDTGLSYLSTMSSLRSLYL--RWCCQV-------QDFGLKHLLALGSLRLLS 428
L G S T++ S +L +WC + Q F K L + L +
Sbjct: 414 HLGL------YGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLST 467
Query: 429 PAGC-PLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCL 476
P G P L + L G +++CPG Y + RCL
Sbjct: 468 PGGSHPALCSLNLRGTRVTPSTVSSVISSCPG-----LLYLNLESCRCL 511
>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
sapiens]
Length = 424
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/193 (23%), Positives = 84/193 (43%), Gaps = 14/193 (7%)
Query: 99 EKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPV---LHAKELYNVLPGGEK 155
+++L G+F E ++ VCK W R+ W L LH +L G
Sbjct: 102 DELLLGIFSCLCLPELLKVSGVCKRWYRLASDESLWQTLDLTGKNLHPDVTGRLLSQGVI 161
Query: 156 EFVNLQGFAARGF-EGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVM- 213
F + F + E F V +D+ + + + G+ + K ++ GL +
Sbjct: 162 AFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVS-TLHGILSQCSKLQNLSLEGLRLSD 220
Query: 214 -----LEQMQGVVRLELSGCNDFTEAGLWSSLS--ARITSLSVSDCINVADDAI-AAISQ 265
L + +VRL LSGC+ F+E L + LS +R+ L++S C + + + A++
Sbjct: 221 PIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAH 280
Query: 266 LLPNLAELSLQAY 278
+ + +L+L Y
Sbjct: 281 VSETITQLNLSGY 293
Score = 37.7 bits (86), Expect = 0.023
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 6/166 (3%)
Query: 312 VVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITD----MALEYV 367
+VN + NL L+LSGCS ++ ++ + + +L L+LSWC T+ +A+ +V
Sbjct: 222 IVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRLDELNLSWCFDFTEKHVQVAVAHV 281
Query: 368 ACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRLL 427
+ + +L + ++ +D + + +L L L +++ + L L+ L
Sbjct: 282 SETITQLNLSGYRKNLQKSDLS-TLVRRCPNLVHLDLSDSVMLKNDCFQEFFQLNYLQHL 340
Query: 428 SPAGCPLLTTTGLSGLVQLQELEELELTN-CPGATPELFKYFSQHL 472
S + C + L L ++ L+ L++ P T +L K HL
Sbjct: 341 SLSRCYDIIPETLLELGEIPTLKTLQVFGIVPDGTLQLLKEALPHL 386
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 45.1 bits (105), Expect = 1e-04
Identities = 35/101 (34%), Positives = 42/101 (41%), Gaps = 18/101 (17%)
Query: 4 PGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPP-------PPTLP 56
PG+ PP LP + V PG P L +A G P P PPP PP LP
Sbjct: 558 PGMPPPVMPPSLPTS--VPPPGMPPSLSSA----GPP-----PVLPPPSLSSAGPPPVLP 606
Query: 57 PPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLAT 97
PPSL++ + P + A P PG P PP T
Sbjct: 607 PPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLT 647
Score = 34.7 bits (78), Expect = 0.20
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 9/52 (17%)
Query: 49 PPPPPTLP----PPSLAAPLSRAALAGGPCT--PAGGPASALAPGHPAERPP 94
PPP PT+P PPSL P+ AL P T P G P + P P PP
Sbjct: 527 PPPLPTMPPPVLPPSLPPPVMPPAL---PATVPPPGMPPPVMPPSLPTSVPP 575
Score = 32.7 bits (73), Expect = 0.75
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 3/58 (5%)
Query: 10 PKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRA 67
P PP G + P P + +T+ P PPPPP PPP + P + A
Sbjct: 1514 PPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPI---PPPPPPPPLPPPPPVIKPQTSA 1568
Score = 31.2 bits (69), Expect = 2.2
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 7/55 (12%)
Query: 46 PCQPPP------PPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPP 94
P PPP P T+PPP + P+ +L P G P S + G P PP
Sbjct: 540 PSLPPPVMPPALPATVPPPGMPPPVMPPSLPTS-VPPPGMPPSLSSAGPPPVLPP 593
Score = 30.4 bits (67), Expect = 3.7
Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 7/94 (7%)
Query: 4 PGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAP 63
P + PP LP V PG P + S+ P P PP + PP + P
Sbjct: 540 PSLPPPVMPPALPAT--VPPPGMPPPVMPPSLPTSVPP----PGMPPSLSSAGPPPVLPP 593
Query: 64 LSRAALAGGPCTPAGGPASALAPGHPAERPPLAT 97
S ++ P P S+ AP PPL++
Sbjct: 594 PSLSSAGPPPVLPPPS-LSSTAPPPVMPLPPLSS 626
Score = 30.0 bits (66), Expect = 4.8
Identities = 16/47 (34%), Positives = 20/47 (42%)
Query: 48 QPPPPPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPP 94
+PPPP PP S+ P + A + P T P P P PP
Sbjct: 1513 RPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPP 1559
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 44.3 bits (103), Expect = 2e-04
Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 23/114 (20%)
Query: 1 MSSPGIDGDPKPPCL----PRNGLVKLPGQPNGLGAASITKGTPAT-KNRPCQPPP---- 51
+++P G P P P+ GL P+ GA + TP + K P PPP
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLAT----PSPKGAPTTPAATPPSPKGGPATPPPKGAP 1264
Query: 52 -PPTLPPPSLAAPLSRAALAGG-------PCTPAGGPASALAPGHPAERPPLAT 97
PP PPSL L+ G P +P GGPA++ G P PP AT
Sbjct: 1265 TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT--PPAAT 1316
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/99 (32%), Positives = 37/99 (37%), Gaps = 12/99 (12%)
Query: 10 PKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAA- 68
P P P P GL TP+ K P P P P LA P + A
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLA-------TPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241
Query: 69 --LAGGPCTPAGGPASALAPGHPAERPPLATDEKILNGL 105
A P +P GGPA+ G P PP AT + GL
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPT--PPAATPPSLKGGL 1278
Score = 40.4 bits (93), Expect = 0.004
Identities = 36/113 (31%), Positives = 43/113 (38%), Gaps = 24/113 (21%)
Query: 2 SSPGIDGDPKPPCL----PRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPP---PT 54
++P G P PP P+ GL P + GA + TP + PPP PT
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHK----GAPTTPAATPPSPKGGLATPPPKGAPT 1150
Query: 55 LP---PPSLAAPLSRAALAGGPCTPAGGPASAL----------APGHPAERPP 94
P PPS L+ G P TPA P S AP PA PP
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Score = 39.3 bits (90), Expect = 0.008
Identities = 33/109 (30%), Positives = 43/109 (39%), Gaps = 23/109 (21%)
Query: 1 MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTP--------ATKNRPCQPPPP 52
+++P G P P V P P G A S KG P + K P PPP
Sbjct: 1278 LATPPHKGAPNPA-------VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 53 PTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAER----PPLAT 97
PP++ P + G P PA P+S P P+ + PP AT
Sbjct: 1331 GAPTPPAVTPPSPK----GTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Score = 38.9 bits (89), Expect = 0.010
Identities = 33/103 (32%), Positives = 38/103 (36%), Gaps = 27/103 (26%)
Query: 2 SSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLA 61
++P + G P PP P P KG PAT + P P PP PPS
Sbjct: 1072 ATPSLKGAPTPPAAT-------PPSP---------KGGPATPS-PKGAPMPPAATPPSPK 1114
Query: 62 APLSRAALAGGPCTPAGGPASAL----------APGHPAERPP 94
L+ G P TPA P S AP PA PP
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1157
Score = 38.5 bits (88), Expect = 0.014
Identities = 40/132 (30%), Positives = 47/132 (35%), Gaps = 39/132 (29%)
Query: 2 SSPGIDGDPKPPCL------------PRNG----LVKLPGQPNGLGAASITKGT------ 39
++P G P PP P G V P P G A S KG
Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315
Query: 40 --PATKNRPCQPPP-----PPTLPPPS----LAAPLSRAALAGGPCTPA---GGPASALA 85
P+ K P PPP PP + PPS P + + GGP TP+ G A
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375
Query: 86 PGH---PAERPP 94
P H PA PP
Sbjct: 1376 PSHKGGPAMTPP 1387
Score = 37.7 bits (86), Expect = 0.023
Identities = 32/102 (31%), Positives = 38/102 (37%), Gaps = 25/102 (24%)
Query: 2 SSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLA 61
+SP G P PP P P KG PAT + P PP PP
Sbjct: 932 ASPSPKGAPTPPAAT-------PPSP---------KGGPATPSPKWAPTPPAATPPSPKG 975
Query: 62 APLSRAAL------AGGPCTPAGGPASAL---APGHPAERPP 94
P + + A P +P GGPA+ AP PA PP
Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017
Score = 37.4 bits (85), Expect = 0.030
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 10/94 (10%)
Query: 10 PKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAAL 69
P P P L P A KG PA+ + P PP PP P + +
Sbjct: 903 PAPKQAP--ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 70 ------AGGPCTPAGGPASALAPGHPAERPPLAT 97
A P +P GGPA+ G P PP AT
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPT--PPAAT 992
Score = 37.0 bits (84), Expect = 0.040
Identities = 36/110 (32%), Positives = 45/110 (40%), Gaps = 16/110 (14%)
Query: 1 MSSPGIDGDPKPPCL----PRNGLVKLP--GQPNGLGAASIT-KG---TPATKNRPCQPP 50
+++P G P P P+ GL P G P A + KG TP+ K P P
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199
Query: 51 PPPTLPPPSLAAPLSRAAL---AGGPCTPAGG---PASALAPGHPAERPP 94
P P LA P + A A P +P GG P+ AP PA PP
Sbjct: 1200 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1249
Score = 36.2 bits (82), Expect = 0.068
Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 9/109 (8%)
Query: 1 MSSPGIDGDPKPPCLPRNGLVK---LPGQPNGLGAAS-ITKGTPATKNRPCQPPPPPTLP 56
++ P G P P+ P P G AA+ + KG P T P
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073
Query: 57 PPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNGL 105
P AP AA P +P GGPA+ G P PP AT GL
Sbjct: 1074 PSLKGAPTPPAAT---PPSPKGGPATPSPKGAP--MPPAATPPSPKGGL 1117
Score = 35.0 bits (79), Expect = 0.15
Identities = 29/89 (32%), Positives = 32/89 (35%), Gaps = 5/89 (5%)
Query: 8 GDPKPPCLPRNGLVKLPGQ--PNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLS 65
GD PP + L K P P G A +KG P PP P P P A S
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP--AVTPPSPKEPPAPKQVATSS 1488
Query: 66 RAALAGGPCTPAGGPA-SALAPGHPAERP 93
A P G P A+ P P E P
Sbjct: 1489 SPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517
Score = 34.7 bits (78), Expect = 0.20
Identities = 30/103 (29%), Positives = 38/103 (36%), Gaps = 17/103 (16%)
Query: 2 SSPGIDGDPKPPCL----PRNGLVKLPGQPNGLGAAS-------ITKGTPATKNRPCQPP 50
++P P PP P+ G P P+ GA + KG PAT + P
Sbjct: 955 ATPSPKWAPTPPAATPPSPKGG----PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT 1010
Query: 51 PPPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERP 93
PP PP +P + G PA P S G PA P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPS--PKGSPAATP 1051
Score = 33.9 bits (76), Expect = 0.34
Identities = 34/112 (30%), Positives = 40/112 (35%), Gaps = 13/112 (11%)
Query: 2 SSPGIDGDPKPPCLPRNGLVKLP---GQPNGLGAASITKGTPATKNRPCQPPPPPTLPP- 57
S G G P P P V P G P +KG P T + P PP P
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 58 ---PSLAAPLSRAALA-----GGPCTPAGGPAS-ALAPGHPAERPPLATDEK 100
P++ P + A G P +PA P S AP P R AT K
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK 1430
Score = 33.5 bits (75), Expect = 0.44
Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 7/74 (9%)
Query: 32 AASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAE 91
+AS++ + P P P PTLPP P S + P P LAP E
Sbjct: 1787 SASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP-------LAPADEDE 1839
Query: 92 RPPLATDEKILNGL 105
PL E I G+
Sbjct: 1840 LLPLIPPEPISGGV 1853
Score = 33.1 bits (74), Expect = 0.57
Identities = 30/97 (30%), Positives = 38/97 (39%), Gaps = 20/97 (20%)
Query: 4 PGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPP----PPPTLPPPS 59
P GDP P + +P P A TP T+ P PP + P S
Sbjct: 1396 PSPKGDPTSPAV-------IPLSPKKAPA------TPVTREGAATPSKGDLTPPAVTPVS 1442
Query: 60 LAAPLSRAALAGGPCTPA--GGPA-SALAPGHPAERP 93
L + +A GGP TP+ G P A+ P P E P
Sbjct: 1443 LKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479
Score = 32.3 bits (72), Expect = 0.97
Identities = 36/119 (30%), Positives = 43/119 (36%), Gaps = 19/119 (15%)
Query: 2 SSPGIDGDPKPPCL----PRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPP 57
++P G P P P+ G P P+ GA + TP + P P P
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGG----PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPM 1104
Query: 58 PSLAAPLS-RAALA-----GGPCTPAGGPAS-----ALAPGHPAERPPLATDEKILNGL 105
P A P S + LA G P TPA P S A P A P AT GL
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Score = 31.2 bits (69), Expect = 2.2
Identities = 32/101 (31%), Positives = 36/101 (35%), Gaps = 9/101 (8%)
Query: 3 SPGIDGDPKPPC---LPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPP-- 57
SP P PP P V P P G+ TP+ N P P T P
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVT-PLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 58 -PSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLAT 97
P+L+ S A P G PAS G P PP AT
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPT--PPAAT 946
Score = 30.0 bits (66), Expect = 4.8
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 19/80 (23%)
Query: 36 TKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAALA------------------GGPCTPA 77
+K +PAT + P PP P P PS PLS + GP TPA
Sbjct: 846 SKDSPATTHSPT-PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904
Query: 78 GGPASALAPGHPAERPPLAT 97
A AL+ + + AT
Sbjct: 905 PKQAPALSMTSSSPKKARAT 924
>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
Length = 684
Score = 43.9 bits (102), Expect = 3e-04
Identities = 40/126 (31%), Positives = 48/126 (38%), Gaps = 33/126 (26%)
Query: 5 GIDGDPKPPCLP-------------RNGLVKLPGQPNGLGAASITKGTPATKNRPCQ--- 48
GIDG+ PP LP + G LPG P G+ + G P K P +
Sbjct: 47 GIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLP-GVDGLTGRDGPPGPKGAPGERGS 105
Query: 49 --PPPPPTLPPPSLAAPLSRAALAG--------GPCTPA------GGPASALAPGHPAER 92
PP PP L L P A ++G GP P+ G P PGHP
Sbjct: 106 LGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVL 165
Query: 93 PPLATD 98
P ATD
Sbjct: 166 PEGATD 171
Score = 32.3 bits (72), Expect = 0.97
Identities = 30/109 (27%), Positives = 36/109 (33%), Gaps = 13/109 (11%)
Query: 3 SPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASI-----TKGTPATKNRPCQPPPPPTLPP 57
+PG G PP P G LPG P G + +G P P P PP P
Sbjct: 99 APGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGP 158
Query: 58 PSLAAPLSRAA--------LAGGPCTPAGGPASALAPGHPAERPPLATD 98
P L A GP P G P G+ E+ + D
Sbjct: 159 PGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKD 207
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/90 (35%), Positives = 37/90 (41%), Gaps = 7/90 (7%)
Query: 2 SSPGIDGDPKPPCLPRNGLVKLPGQPNGL-GAASITKGTPATKNRPCQPPPPPTLP-PPS 59
S PG P PP LP G ++P P L G+A I P PPPPP LP P
Sbjct: 659 SLPGGTAIPPPPPLP--GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 716
Query: 60 LAAPLSRAALAGGPCTPAGGPASALAPGHP 89
+ P GGP P P + P P
Sbjct: 717 IPPP---PPFPGGPGIPPPPPGMGMPPPPP 743
Score = 38.9 bits (89), Expect = 0.010
Identities = 31/87 (35%), Positives = 34/87 (39%), Gaps = 7/87 (8%)
Query: 8 GDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRA 67
G P P LP G +P P G+A I P PPPPP LP + P
Sbjct: 653 GIPSPSSLP--GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA-GMPPPPP 709
Query: 68 ALAGGPCTPAGGPASALAPGHPAERPP 94
L GGP P P PG P PP
Sbjct: 710 PLPGGPGIPPPPP----FPGGPGIPPP 732
Score = 34.7 bits (78), Expect = 0.20
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 19/94 (20%)
Query: 12 PPCLPRNGLVK-LPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAALA 70
PP +P V P P G P P PPPPP PPP L
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP----------LP 613
Query: 71 GGPC---TPAGGPASALAPGHPAERPPLATDEKI 101
GG C P+ +A++P PPL+ D I
Sbjct: 614 GGVCISSPPSLPGGTAISP-----PPPLSGDATI 642
Score = 33.5 bits (75), Expect = 0.44
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 10 PKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAAL 69
P PP P G V + P+ G +I+ P + + PPPP P + P S ++L
Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP---LPEGVGIP-SPSSL 660
Query: 70 AGGPCTPAGG--PASALAPGHPAERPPL 95
GG P P SA P P PPL
Sbjct: 661 PGGTAIPPPPPLPGSARIPPPP---PPL 685
Score = 33.5 bits (75), Expect = 0.44
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 3/78 (3%)
Query: 10 PKPPCLPRNGLVKLPGQPNGL-GAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAA 68
P PP LP G +P P L G A + P P PPPPP P + P
Sbjct: 680 PPPPPLP--GSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737
Query: 69 LAGGPCTPAGGPASALAP 86
+ P G PA+ + P
Sbjct: 738 MPPPPPFGFGVPAAPVLP 755
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/90 (35%), Positives = 37/90 (41%), Gaps = 7/90 (7%)
Query: 2 SSPGIDGDPKPPCLPRNGLVKLPGQPNGL-GAASITKGTPATKNRPCQPPPPPTLP-PPS 59
S PG P PP LP G ++P P L G+A I P PPPPP LP P
Sbjct: 668 SLPGGTAIPPPPPLP--GSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG 725
Query: 60 LAAPLSRAALAGGPCTPAGGPASALAPGHP 89
+ P GGP P P + P P
Sbjct: 726 IPPP---PPFPGGPGIPPPPPGMGMPPPPP 752
Score = 38.9 bits (89), Expect = 0.010
Identities = 31/87 (35%), Positives = 34/87 (39%), Gaps = 7/87 (8%)
Query: 8 GDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRA 67
G P P LP G +P P G+A I P PPPPP LP + P
Sbjct: 662 GIPSPSSLP--GGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEA-GMPPPPP 718
Query: 68 ALAGGPCTPAGGPASALAPGHPAERPP 94
L GGP P P PG P PP
Sbjct: 719 PLPGGPGIPPPPP----FPGGPGIPPP 741
Score = 34.7 bits (78), Expect = 0.20
Identities = 29/94 (30%), Positives = 35/94 (37%), Gaps = 19/94 (20%)
Query: 12 PPCLPRNGLVK-LPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAALA 70
PP +P V P P G P P PPPPP PPP L
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP----------LP 622
Query: 71 GGPC---TPAGGPASALAPGHPAERPPLATDEKI 101
GG C P+ +A++P PPL+ D I
Sbjct: 623 GGVCISSPPSLPGGTAISP-----PPPLSGDATI 651
Score = 33.5 bits (75), Expect = 0.44
Identities = 29/88 (32%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 10 PKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAAL 69
P PP P G V + P+ G +I+ P + + PPPP P + P S ++L
Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPP---LPEGVGIP-SPSSL 669
Query: 70 AGGPCTPAGG--PASALAPGHPAERPPL 95
GG P P SA P P PPL
Sbjct: 670 PGGTAIPPPPPLPGSARIPPPP---PPL 694
Score = 33.5 bits (75), Expect = 0.44
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 3/78 (3%)
Query: 10 PKPPCLPRNGLVKLPGQPNGL-GAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAA 68
P PP LP G +P P L G A + P P PPPPP P + P
Sbjct: 689 PPPPPLP--GSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746
Query: 69 LAGGPCTPAGGPASALAP 86
+ P G PA+ + P
Sbjct: 747 MPPPPPFGFGVPAAPVLP 764
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 43.5 bits (101), Expect = 4e-04
Identities = 32/84 (38%), Positives = 32/84 (38%), Gaps = 17/84 (20%)
Query: 4 PGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAP 63
PG G P PP LP P G G P PPPPP PPPS
Sbjct: 362 PGRGGPPPPPPPATGRSGPLPPPPPGAGGP------------PMPPPPPPPPPPPS---- 405
Query: 64 LSRAALAGGPCTPAGGPASALAPG 87
S A P PA PA LAPG
Sbjct: 406 -SGNGPAPPPLPPALVPAGGLAPG 428
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
Length = 326
Score = 43.5 bits (101), Expect = 4e-04
Identities = 68/230 (29%), Positives = 98/230 (42%), Gaps = 21/230 (9%)
Query: 260 IAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSL 319
+ A+ Q PNL L L HV D ++ T+ + TL L SC EI+ + +H
Sbjct: 94 LRALGQKCPNLKRLCL---HVADLSMVPITSLPS-TLRTLELHSC-EIS----MAWLHKQ 144
Query: 320 PNLTALSLSGCSKVTDDGVELVAENL------RKLRSLDLSWCPRITDMALEYVACDLHR 373
+ T L L C V D E+L R LRSL L R+T+ L+ +L
Sbjct: 145 QDPTVLPLLECI-VLDRVPAFRDEHLQGLTRFRALRSLVLGGTYRVTETGLDAGLQELSY 203
Query: 374 LEELVLDRCVRITDTGLSYLST-MSSLRSLYL--RWCCQVQDFGLKHLLALGSLRLLSPA 430
L+ L + C D+ L +S + +R + L R L+ + AL SL L P
Sbjct: 204 LQRLEVLGCTLSADSTLLAISRHLRDVRKIRLTVRGLSAPGLAVLEGMPALESLCLQGPL 263
Query: 431 GCPLLT--TTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVI 478
P + T LS + + +L LEL E K + LP C+VI
Sbjct: 264 VTPEMPSPTEILSSCLTMPKLRVLELQGLGWEGQEAEKILCKGLPHCMVI 313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,439,041
Number of Sequences: 37866
Number of extensions: 1214562
Number of successful extensions: 16301
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 307
Number of HSP's successfully gapped in prelim test: 706
Number of HSP's that attempted gapping in prelim test: 9522
Number of HSP's gapped (non-prelim): 4955
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.