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Search of human proteins with 239757861
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
(2382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 4764 0.0
gi|150378528 G protein-coupled receptor associated sorting prote... 256 2e-67
gi|150378489 G protein-coupled receptor associated sorting prote... 256 2e-67
gi|103472136 G protein-coupled receptor associated sorting prote... 256 2e-67
gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens] 236 2e-61
gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens] 236 2e-61
gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens] 236 2e-61
gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens] 224 1e-57
gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens] 220 1e-56
gi|51702248 G protein-coupled receptor associated sorting protei... 218 6e-56
gi|19923967 G protein-coupled receptor associated sorting protei... 218 6e-56
gi|238776793 SVH protein isoform b [Homo sapiens] 205 5e-52
gi|31377663 SVH protein isoform a [Homo sapiens] 205 5e-52
gi|7662162 ALEX2 protein [Homo sapiens] 204 1e-51
gi|29540562 ALEX2 protein [Homo sapiens] 204 1e-51
gi|216547715 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|216547682 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|216547672 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|216547663 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|216547655 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|216547646 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|216547639 basic helix-loop-helix domain containing, class B, ... 181 8e-45
gi|39930463 basic helix-loop-helix domain containing, class B, 9... 181 8e-45
gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo s... 172 5e-42
gi|238776797 SVH protein isoform e [Homo sapiens] 169 2e-41
gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo s... 169 3e-41
gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo s... 169 3e-41
gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo s... 122 5e-27
gi|113415138 PREDICTED: similar to SVH protein isoform 2 [Homo s... 119 4e-26
gi|169165133 PREDICTED: similar to SVH protein isoform 1 [Homo s... 119 4e-26
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 4764 bits (12357), Expect = 0.0
Identities = 2382/2382 (100%), Positives = 2382/2382 (100%)
Query: 1 MSAAGLKITGSKETKRRLLLISIDWVYCQEKQEERRELPRIITGPPPEAAVVAFEWLKTS 60
MSAAGLKITGSKETKRRLLLISIDWVYCQEKQEERRELPRIITGPPPEAAVVAFEWLKTS
Sbjct: 1 MSAAGLKITGSKETKRRLLLISIDWVYCQEKQEERRELPRIITGPPPEAAVVAFEWLKTS 60
Query: 61 TLTGLHPQLPLSLPQPECALPYLVRAFSRGDYMGRIQEVGWVTAGLVIWAGTCYYIYKFT 120
TLTGLHPQLPLSLPQPECALPYLVRAFSRGDYMGRIQEVGWVTAGLVIWAGTCYYIYKFT
Sbjct: 61 TLTGLHPQLPLSLPQPECALPYLVRAFSRGDYMGRIQEVGWVTAGLVIWAGTCYYIYKFT 120
Query: 121 KGRAQSVRTLARNGSTVKMETVVGVQSQTLAINEAEIKTKPQVEIGAETGARSGPGAEVE 180
KGRAQSVRTLARNGSTVKMETVVGVQSQTLAINEAEIKTKPQVEIGAETGARSGPGAEVE
Sbjct: 121 KGRAQSVRTLARNGSTVKMETVVGVQSQTLAINEAEIKTKPQVEIGAETGARSGPGAEVE 180
Query: 181 TKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAV 240
TKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAV
Sbjct: 181 TKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAV 240
Query: 241 TQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVT 300
TQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVT
Sbjct: 241 TQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVT 300
Query: 301 QSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATVDARGNPNGMS 360
QSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATVDARGNPNGMS
Sbjct: 301 QSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATVDARGNPNGMS 360
Query: 361 REVAGVDMKSCAQSQAVTKIQGDDMPGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKT 420
REVAGVDMKSCAQSQAVTKIQGDDMPGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKT
Sbjct: 361 REVAGVDMKSCAQSQAVTKIQGDDMPGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKT 420
Query: 421 QTEAIPGAKIDAGGNTNAMCKVGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVIS 480
QTEAIPGAKIDAGGNTNAMCKVGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVIS
Sbjct: 421 QTEAIPGAKIDAGGNTNAMCKVGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVIS 480
Query: 481 KAITGADMRAAAQPQAVASTHAEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDA 540
KAITGADMRAAAQPQAVASTHAEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDA
Sbjct: 481 KAITGADMRAAAQPQAVASTHAEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDA 540
Query: 541 RDKSRGNPNVMAKVGDGTDMLSCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDM 600
RDKSRGNPNVMAKVGDGTDMLSCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDM
Sbjct: 541 RDKSRGNPNVMAKVGDGTDMLSCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDM 600
Query: 601 KAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDG 660
KAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDG
Sbjct: 601 KAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDG 660
Query: 661 RGNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSA 720
RGNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSA
Sbjct: 661 RGNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSA 720
Query: 721 QPEAVVSFQGEALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDSKNKV 780
QPEAVVSFQGEALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDSKNKV
Sbjct: 721 QPEAVVSFQGEALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDSKNKV 780
Query: 781 KGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSA 840
KGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSA
Sbjct: 781 KGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSA 840
Query: 841 RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKV 900
RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKV
Sbjct: 841 RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKV 900
Query: 901 RGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGST 960
RGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGST
Sbjct: 901 RGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGST 960
Query: 961 QPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKV 1020
QPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKV
Sbjct: 961 QPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKV 1020
Query: 1021 KGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSA 1080
KGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSA
Sbjct: 1021 KGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSA 1080
Query: 1081 QPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKS 1140
QPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKS
Sbjct: 1081 QPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKS 1140
Query: 1141 MSTSEAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAA 1200
MSTSEAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAA
Sbjct: 1141 MSTSEAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAA 1200
Query: 1201 ERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAG 1260
ERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAG
Sbjct: 1201 ERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAG 1260
Query: 1261 ARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAG 1320
ARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAG
Sbjct: 1261 ARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAG 1320
Query: 1321 NQAIGELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSS 1380
NQAIGELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSS
Sbjct: 1321 NQAIGELWAAGQASDGSWPGGQASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSS 1380
Query: 1381 VSYWAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQS 1440
VSYWAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQS
Sbjct: 1381 VSYWAGVVDQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQS 1440
Query: 1441 SGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQ 1500
SGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQ
Sbjct: 1441 SGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQ 1500
Query: 1501 AGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQ 1560
AGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQ
Sbjct: 1501 AGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKPIFEDQ 1560
Query: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASG 1620
VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASG
Sbjct: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASG 1620
Query: 1621 QDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPG 1680
QDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPG
Sbjct: 1621 QDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPG 1680
Query: 1681 AGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSSGRSWI 1740
AGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSSGRSWI
Sbjct: 1681 AGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSSGRSWI 1740
Query: 1741 GPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGG 1800
GPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGG
Sbjct: 1741 GPGDQAVDCSKPEFEDQACGGGSWAGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGG 1800
Query: 1801 SWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTA 1860
SWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTA
Sbjct: 1801 SWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTA 1860
Query: 1861 SRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAG 1920
SRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAG
Sbjct: 1861 SRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAG 1920
Query: 1921 AEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEAGVESWTLARNVGEDELS 1980
AEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEAGVESWTLARNVGEDELS
Sbjct: 1921 AEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGEEAGVESWTLARNVGEDELS 1980
Query: 1981 RESSPDIEEISLRSLFWAESENSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGS 2040
RESSPDIEEISLRSLFWAESENSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGS
Sbjct: 1981 RESSPDIEEISLRSLFWAESENSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGS 2040
Query: 2041 WFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEAS 2100
WFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEAS
Sbjct: 2041 WFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEAS 2100
Query: 2101 FPVEDESRKQTRTGEKTRPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYN 2160
FPVEDESRKQTRTGEKTRPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYN
Sbjct: 2101 FPVEDESRKQTRTGEKTRPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYN 2160
Query: 2161 SADYSYSHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVC 2220
SADYSYSHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVC
Sbjct: 2161 SADYSYSHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVC 2220
Query: 2221 EDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLL 2280
EDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLL
Sbjct: 2221 EDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLL 2280
Query: 2281 NFSKNPSMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKF 2340
NFSKNPSMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKF
Sbjct: 2281 NFSKNPSMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKF 2340
Query: 2341 SKNSLYFLFQRPKACAKKLRALAAECNDPEVKERVELLISKL 2382
SKNSLYFLFQRPKACAKKLRALAAECNDPEVKERVELLISKL
Sbjct: 2341 SKNSLYFLFQRPKACAKKLRALAAECNDPEVKERVELLISKL 2382
>gi|150378528 G protein-coupled receptor associated sorting protein 1
[Homo sapiens]
Length = 1395
Score = 256 bits (653), Expect = 2e-67
Identities = 362/1510 (23%), Positives = 595/1510 (39%), Gaps = 256/1510 (16%)
Query: 981 KGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSV 1040
K VV A D +P+V +Q + +PGAR K K +M
Sbjct: 17 KPGEEVVGGAEIENDVPLVVRPKV--RTQAQIMPGARPKNKSK------------VMPGA 62
Query: 1041 QVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKV 1100
+V S G P +K K A+P + + AQP+ A S+T ++ +
Sbjct: 63 STKVETSAVGGARPKSKAK------AIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNI 116
Query: 1101 KGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEA 1160
+ + + A T++ ++ + + + E+ P + + + +++E
Sbjct: 117 IASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWC 176
Query: 1161 EAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIKF--RFQTMDGDWENS 1218
PTS+ E + + ++ +W+G V +K R M N+
Sbjct: 177 CPRPTSKQEASPNSDF-KWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANT 235
Query: 1219 VSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQ 1278
+S + E I S SG+ D++ + W A D+T+ +W+G R + +R+ +
Sbjct: 236 MSRSQTNQELYIASSSGSEDES-VKTPWFWARDKTN--TWSGPREDPN------SRSRFR 286
Query: 1279 ASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQAS---- 1334
+ ++ ++S G+ D +W GA +A S AG +A +
Sbjct: 287 SKKEVYV--ESSSGSEHEDHLE--SWFGAGKEAKFRSKMRAGKEANNRARHRAKREACID 342
Query: 1335 --DGS----------WPGGQASGVS--WVGEEAIGGSWTG----------------AENQ 1364
GS WP A+ S + +EA + T +E +
Sbjct: 343 FMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEE 402
Query: 1365 ASEGSWAGA----GAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGG------SKPRFEDQ 1414
A G+W A + +S+ V D++ GSW T +++ G S+PR + +
Sbjct: 403 ALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGE 462
Query: 1415 ASGEGSWAG-------AGGQASGGSMLGPED-QSSGRSWADTADQASGGSRLGHVDQSSG 1466
G+ + G +A+ S+L +D Q SW ++ + + +++
Sbjct: 463 RIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAE----EETIF 518
Query: 1467 GAWAGTLD----QSGGGSKPRFENQTTEE---GSWAGAGGQA------GGGSKVGPEDQS 1513
G+W +D +SG G ++ EE G W +G Q G ++ G E+++
Sbjct: 519 GSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEET 578
Query: 1514 SGRSWANSGDQI--------SGGFLVGIVDQANG-GSW----TGAGHPASVGPKPIFEDQ 1560
SW + +Q S + G ++ GSW A V K ED+
Sbjct: 579 IFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDK 638
Query: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWF----CVCPGSQTNGGSWG 1616
A+E+V G+R + + T +++ W C+ P GGSW
Sbjct: 639 EEAMIPCFGAKEEVSMKHGTGVRCRFMAGA-EETNNKSCFWAEKEPCMYPAG---GGSWK 694
Query: 1617 GASGQDVGGSRPGPTNQSSAGSW------DSPGSQVSGSCW-TGAGAVDQAGGCSKPGFE 1669
SRP + SW P + + W T +D G +K E
Sbjct: 695 ---------SRP-EEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTE 744
Query: 1670 DQAI-GGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWA 1728
++ I FW ED++ ++ +RP + GSW
Sbjct: 745 EETIINSWFW--------------KEDEA-------ISEATDREESRPEAEEGDIIGSWF 783
Query: 1729 GTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGG-----GSWAGAGSQASGESWAGSRPGN 1783
W G D+ ++ ED+ GSW GA + R
Sbjct: 784 ----------WAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETI------RREAG 827
Query: 1784 EAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEA---VIGSWCW 1840
S E++ GSW E+ S E A GF PG E +GSW W
Sbjct: 828 SCSKSSPKAEEEEVIIGSWFWEEE-------ASPEAVAGVGFESKPGTEEEEITVGSWFW 880
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
EE+A I +AG +A+ E E + GSW + G V
Sbjct: 881 PEEEASI----------------QAGSQAVEEMESETEEETIFGSWF------WDGKEVS 918
Query: 1901 AEAGAGAEAGAG------AEAGAGAGAEAGAEAG--AGAGAGPGTESGAGVWSWDGDATT 1952
EAG + E+ + +A E G A + P E GA V SW
Sbjct: 919 EEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDE 978
Query: 1953 VESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWA------ESENSNTF 2006
V++R G G S TLA D +E + S FWA ES S F
Sbjct: 979 VDNRTDNGSNCG--SRTLA--------------DEDEAIVGSWFWAGDEAHFESNPSPVF 1022
Query: 2007 RSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSES 2066
R+ S E + + E G W G + S + PK A E
Sbjct: 1023 RAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF-PKEAASLFCEM 1081
Query: 2067 RGIYPYMVPGAGMGSWDGAMIWSET---KFAHQSEASFPVEDESRKQTRTGEKTRPWSCR 2123
G P + + G +++ + +F Q + S+ E R+ R E T P S
Sbjct: 1082 FGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSS 1141
Query: 2124 C---KHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVI 2180
C + E + + E+L+ ++E DP +HEI+ A+ + ++ + +R+ G +S+I
Sbjct: 1142 CNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLI 1201
Query: 2181 ESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLI 2240
E+LLN P VR L + ++ N ++TY+ +VCE+T+ Y ++S QL+G+R+I
Sbjct: 1202 ETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMI 1261
Query: 2241 RHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTS 2300
RHLT T++Y +V NY+S FL LL G+ +T+ HVL MLLN S+N MTK+LL A A +
Sbjct: 1262 RHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSE 1321
Query: 2301 LINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLR 2360
I +F+++ET +NI L++FENI + K+ F+ D F+ L F + + AK+L+
Sbjct: 1322 FIGLFNREETNDNIQIVLAIFENIGNNIKKET-VFSDDDFNIEPLISAFHKVEKFAKELQ 1380
Query: 2361 ALAAECNDPE 2370
NDPE
Sbjct: 1381 GKTDNQNDPE 1390
Score = 78.2 bits (191), Expect = 9e-14
Identities = 216/1020 (21%), Positives = 372/1020 (36%), Gaps = 210/1020 (20%)
Query: 744 PNVVLKAEVGEGAMGTAQLQIM--ASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQ 801
P V +A++ GA + ++M AS+K E + K + A+ + + Q
Sbjct: 38 PKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQ 97
Query: 802 PQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANSQGEVLPGAKNKVK 861
P+ A + ++ I +P +S + T + + + N+ E P K +
Sbjct: 98 PRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQ 157
Query: 862 ANLNAV--SKAEAGMGATGSVQP----QAVANSHCETLPGAKNKVRGNWNAVS-KAGAGM 914
A SK E MG+ +P +A NS + + + + + + + V+ K G
Sbjct: 158 AGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGN 217
Query: 915 DTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLP 974
+ S + +AN + + ++++ + S +G+ +++V + P A + T
Sbjct: 218 RVKDSNRSMHMANQEANTM--SRSQTNQELYIASSSGSEDESVKT--PWFWARDKTNTWS 273
Query: 975 GARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGA 1034
G R S SK ++ ++ + E+ GA + K S + EA
Sbjct: 274 GPREDPNSRSRFRSKKEVYVESSSGSEHE----DHLESWFGAGKEAKFRSKMRAGKEANN 329
Query: 1035 GIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAG--------------------A 1074
+ + F +PG+ + ++ S P+ A A
Sbjct: 330 RARHRAKREACIDF----MPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEA 385
Query: 1075 DTVGSAQPQAVANSQSETLLG------------------ARNKVKGNTI------AVPKA 1110
T A+ + A S+ E L+G + +V+ +I +A
Sbjct: 386 KTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEA 445
Query: 1111 GTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAE------------------- 1151
G G ++P+ G++L GAR+K+ + AEAT+E
Sbjct: 446 SMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAG 505
Query: 1152 DEAYAKPEAE--------AMPTSESEGGSGTQACRKTQPN----IHDYYWNG--IGVEDW 1197
+E + E E + + E G G +T+ I ++W+G + +E
Sbjct: 506 EEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAG 565
Query: 1198 IAAERWIKFRFQTMDGD--WENSVSWADDENEASIGSWSGASDKAGIIRSW----AVACD 1251
I E +T+ G W + ++ D E S + GA ++ II SW AC
Sbjct: 566 IGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACV 625
Query: 1252 ETSVKSWA-------------GARAENVVGIGTWARAGEQASGGLWAGGQTSEGT---WA 1295
E V S + GA+ E + GT R AG + + WA
Sbjct: 626 EGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRC------RFMAGAEETNNKSCFWA 679
Query: 1296 GDK-----ASGGAWTG--AENQASGGSWALAGNQAIGE------LWAAGQAS-DGSWPGG 1341
+ A GG+W E + SW + E LWA +++ DG+ G
Sbjct: 680 EKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGT--GE 737
Query: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSD 1401
+A ++ EE I SW E++A + A + A D G WAG D
Sbjct: 738 KAKLLT--EEETIINSWFWKEDEAI------SEATDREESRPEAEEGDIIGSWFWAGEED 789
Query: 1402 QSGGGSKPRFEDQASGE-----GSWAGA--------GGQASGGSMLGPEDQSSGRSW--- 1445
+ ++ R ED+ + E GSW GA G S S E++ SW
Sbjct: 790 RLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWE 849
Query: 1446 ADTADQASGG----SRLG-HVDQSSGGAWAGTLD----QSGGGSKPRFENQTTEE---GS 1493
+ + +A G S+ G ++ + G+W + Q+G + E++T EE GS
Sbjct: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909
Query: 1494 WAGAG----GQAGGGSKVGPEDQSS--GRSWANSGDQISGGFLVGIVDQANGGSWTGAGH 1547
W G +AG PED SW S D+ + G
Sbjct: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDK----------------AIKETGT 953
Query: 1548 PASVGPKPIFEDQVSGRGSWADAREQV---------VGDSRLGLRDQSSGDSWAGTGDQA 1598
A+ KP E+ GSW +A ++V G L D++ SW GD+A
Sbjct: 954 VATCESKPENEEGAI-VGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEA 1012
Score = 66.6 bits (161), Expect = 3e-10
Identities = 124/580 (21%), Positives = 227/580 (39%), Gaps = 111/580 (19%)
Query: 155 AEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAG 214
AEI++ QV+ + G GAE+E + + +QA+ M GA P+ +S+ A
Sbjct: 4 AEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGAS 63
Query: 215 TLVMTEAVTLTEVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKR 274
T V T AV K+KA+ + + + +A+ WA + A+R
Sbjct: 64 TKVETSAVGGARPKSKAKAIPVSR------------------FKEEAQMWA-QPRFGAER 104
Query: 275 EAMTQTKAETHILAEKETEINRVMVTQSETLAVPREVA--------KMGATNKTGIVDET 326
+ T+ ++T+I+A + V+V +++ L+ RE+ + A + G +
Sbjct: 105 LSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGF--QP 162
Query: 327 KTRALEETVSVAKTQSEARPGATVDARGNPNGMSREVAGVDMKSCAQSQAVTKIQGDDM- 385
R+ EET S P T +PN D K +S + GD++
Sbjct: 163 SFRSKEET----NMGSWCCPRPTSKQEASPNS--------DFKWVDKSVSSLFWSGDEVT 210
Query: 386 ----PGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCK 441
PG V+D M+ E+ +R+ +++ +
Sbjct: 211 AKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIAS--------------------- 249
Query: 442 VGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTH 501
+G++ + P A+ + SG R D + SK + + ++ + +
Sbjct: 250 -SSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESW 308
Query: 502 AEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDML 561
A +AK +++ +AG +AN RA + + D G+ +V+ K
Sbjct: 309 FGAGKEAKFRSK------MRAGKEANNRARHRAKR-EACIDFMPGSIDVIKKE------- 354
Query: 562 SCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGM--AQSQGEALPNTRGK 619
SC P+ A+T S IK M KE A +A+ A+S+ EAL T
Sbjct: 355 SCFWPE----ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFW 410
Query: 620 ARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
A ++ M ++ ++ E+++ S + + A +K+ R
Sbjct: 411 ATDES----------SMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTD 460
Query: 680 GQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDS 719
G+ + G++L GA+ K T +K GA E T++S
Sbjct: 461 GERI------GDSLFGAREK------TSMKTGA-EATSES 487
>gi|150378489 G protein-coupled receptor associated sorting protein 1
[Homo sapiens]
Length = 1395
Score = 256 bits (653), Expect = 2e-67
Identities = 362/1510 (23%), Positives = 595/1510 (39%), Gaps = 256/1510 (16%)
Query: 981 KGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSV 1040
K VV A D +P+V +Q + +PGAR K K +M
Sbjct: 17 KPGEEVVGGAEIENDVPLVVRPKV--RTQAQIMPGARPKNKSK------------VMPGA 62
Query: 1041 QVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKV 1100
+V S G P +K K A+P + + AQP+ A S+T ++ +
Sbjct: 63 STKVETSAVGGARPKSKAK------AIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNI 116
Query: 1101 KGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEA 1160
+ + + A T++ ++ + + + E+ P + + + +++E
Sbjct: 117 IASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWC 176
Query: 1161 EAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIKF--RFQTMDGDWENS 1218
PTS+ E + + ++ +W+G V +K R M N+
Sbjct: 177 CPRPTSKQEASPNSDF-KWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANT 235
Query: 1219 VSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQ 1278
+S + E I S SG+ D++ + W A D+T+ +W+G R + +R+ +
Sbjct: 236 MSRSQTNQELYIASSSGSEDES-VKTPWFWARDKTN--TWSGPREDPN------SRSRFR 286
Query: 1279 ASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQAS---- 1334
+ ++ ++S G+ D +W GA +A S AG +A +
Sbjct: 287 SKKEVYV--ESSSGSEHEDHLE--SWFGAGKEAKFRSKMRAGKEANNRARHRAKREACID 342
Query: 1335 --DGS----------WPGGQASGVS--WVGEEAIGGSWTG----------------AENQ 1364
GS WP A+ S + +EA + T +E +
Sbjct: 343 FMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEE 402
Query: 1365 ASEGSWAGA----GAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGG------SKPRFEDQ 1414
A G+W A + +S+ V D++ GSW T +++ G S+PR + +
Sbjct: 403 ALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGE 462
Query: 1415 ASGEGSWAG-------AGGQASGGSMLGPED-QSSGRSWADTADQASGGSRLGHVDQSSG 1466
G+ + G +A+ S+L +D Q SW ++ + + +++
Sbjct: 463 RIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAE----EETIF 518
Query: 1467 GAWAGTLD----QSGGGSKPRFENQTTEE---GSWAGAGGQA------GGGSKVGPEDQS 1513
G+W +D +SG G ++ EE G W +G Q G ++ G E+++
Sbjct: 519 GSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEET 578
Query: 1514 SGRSWANSGDQI--------SGGFLVGIVDQANG-GSW----TGAGHPASVGPKPIFEDQ 1560
SW + +Q S + G ++ GSW A V K ED+
Sbjct: 579 IFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDK 638
Query: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWF----CVCPGSQTNGGSWG 1616
A+E+V G+R + + T +++ W C+ P GGSW
Sbjct: 639 EEAMIPCFGAKEEVSMKHGTGVRCRFMAGA-EETNNKSCFWAEKEPCMYPAG---GGSWK 694
Query: 1617 GASGQDVGGSRPGPTNQSSAGSW------DSPGSQVSGSCW-TGAGAVDQAGGCSKPGFE 1669
SRP + SW P + + W T +D G +K E
Sbjct: 695 ---------SRP-EEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTE 744
Query: 1670 DQAI-GGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWA 1728
++ I FW ED++ ++ +RP + GSW
Sbjct: 745 EETIINSWFW--------------KEDEA-------ISEATDREESRPEAEEGDIIGSWF 783
Query: 1729 GTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGG-----GSWAGAGSQASGESWAGSRPGN 1783
W G D+ ++ ED+ GSW GA + R
Sbjct: 784 ----------WAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETI------RREAG 827
Query: 1784 EAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEA---VIGSWCW 1840
S E++ GSW E+ S E A GF PG E +GSW W
Sbjct: 828 SCSKSSPKAEEEEVIIGSWFWEEE-------ASPEAVAGVGFESKPGTEEEEITVGSWFW 880
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
EE+A I +AG +A+ E E + GSW + G V
Sbjct: 881 PEEEASI----------------QAGSQAVEEMESETEEETIFGSWF------WDGKEVS 918
Query: 1901 AEAGAGAEAGAG------AEAGAGAGAEAGAEAG--AGAGAGPGTESGAGVWSWDGDATT 1952
EAG + E+ + +A E G A + P E GA V SW
Sbjct: 919 EEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDE 978
Query: 1953 VESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWA------ESENSNTF 2006
V++R G G S TLA D +E + S FWA ES S F
Sbjct: 979 VDNRTDNGSNCG--SRTLA--------------DEDEAIVGSWFWAGDEAHFESNPSPVF 1022
Query: 2007 RSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSES 2066
R+ S E + + E G W G + S + PK A E
Sbjct: 1023 RAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF-PKEAASLFCEM 1081
Query: 2067 RGIYPYMVPGAGMGSWDGAMIWSET---KFAHQSEASFPVEDESRKQTRTGEKTRPWSCR 2123
G P + + G +++ + +F Q + S+ E R+ R E T P S
Sbjct: 1082 FGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSS 1141
Query: 2124 C---KHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVI 2180
C + E + + E+L+ ++E DP +HEI+ A+ + ++ + +R+ G +S+I
Sbjct: 1142 CNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLI 1201
Query: 2181 ESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLI 2240
E+LLN P VR L + ++ N ++TY+ +VCE+T+ Y ++S QL+G+R+I
Sbjct: 1202 ETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMI 1261
Query: 2241 RHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTS 2300
RHLT T++Y +V NY+S FL LL G+ +T+ HVL MLLN S+N MTK+LL A A +
Sbjct: 1262 RHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSE 1321
Query: 2301 LINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLR 2360
I +F+++ET +NI L++FENI + K+ F+ D F+ L F + + AK+L+
Sbjct: 1322 FIGLFNREETNDNIQIVLAIFENIGNNIKKET-VFSDDDFNIEPLISAFHKVEKFAKELQ 1380
Query: 2361 ALAAECNDPE 2370
NDPE
Sbjct: 1381 GKTDNQNDPE 1390
Score = 78.2 bits (191), Expect = 9e-14
Identities = 216/1020 (21%), Positives = 372/1020 (36%), Gaps = 210/1020 (20%)
Query: 744 PNVVLKAEVGEGAMGTAQLQIM--ASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQ 801
P V +A++ GA + ++M AS+K E + K + A+ + + Q
Sbjct: 38 PKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQ 97
Query: 802 PQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANSQGEVLPGAKNKVK 861
P+ A + ++ I +P +S + T + + + N+ E P K +
Sbjct: 98 PRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQ 157
Query: 862 ANLNAV--SKAEAGMGATGSVQP----QAVANSHCETLPGAKNKVRGNWNAVS-KAGAGM 914
A SK E MG+ +P +A NS + + + + + + + V+ K G
Sbjct: 158 AGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGN 217
Query: 915 DTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLP 974
+ S + +AN + + ++++ + S +G+ +++V + P A + T
Sbjct: 218 RVKDSNRSMHMANQEANTM--SRSQTNQELYIASSSGSEDESVKT--PWFWARDKTNTWS 273
Query: 975 GARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGA 1034
G R S SK ++ ++ + E+ GA + K S + EA
Sbjct: 274 GPREDPNSRSRFRSKKEVYVESSSGSEHE----DHLESWFGAGKEAKFRSKMRAGKEANN 329
Query: 1035 GIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAG--------------------A 1074
+ + F +PG+ + ++ S P+ A A
Sbjct: 330 RARHRAKREACIDF----MPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEA 385
Query: 1075 DTVGSAQPQAVANSQSETLLG------------------ARNKVKGNTI------AVPKA 1110
T A+ + A S+ E L+G + +V+ +I +A
Sbjct: 386 KTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEA 445
Query: 1111 GTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAE------------------- 1151
G G ++P+ G++L GAR+K+ + AEAT+E
Sbjct: 446 SMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAG 505
Query: 1152 DEAYAKPEAE--------AMPTSESEGGSGTQACRKTQPN----IHDYYWNG--IGVEDW 1197
+E + E E + + E G G +T+ I ++W+G + +E
Sbjct: 506 EEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAG 565
Query: 1198 IAAERWIKFRFQTMDGD--WENSVSWADDENEASIGSWSGASDKAGIIRSW----AVACD 1251
I E +T+ G W + ++ D E S + GA ++ II SW AC
Sbjct: 566 IGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACV 625
Query: 1252 ETSVKSWA-------------GARAENVVGIGTWARAGEQASGGLWAGGQTSEGT---WA 1295
E V S + GA+ E + GT R AG + + WA
Sbjct: 626 EGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRC------RFMAGAEETNNKSCFWA 679
Query: 1296 GDK-----ASGGAWTG--AENQASGGSWALAGNQAIGE------LWAAGQAS-DGSWPGG 1341
+ A GG+W E + SW + E LWA +++ DG+ G
Sbjct: 680 EKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGT--GE 737
Query: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSD 1401
+A ++ EE I SW E++A + A + A D G WAG D
Sbjct: 738 KAKLLT--EEETIINSWFWKEDEAI------SEATDREESRPEAEEGDIIGSWFWAGEED 789
Query: 1402 QSGGGSKPRFEDQASGE-----GSWAGA--------GGQASGGSMLGPEDQSSGRSW--- 1445
+ ++ R ED+ + E GSW GA G S S E++ SW
Sbjct: 790 RLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWE 849
Query: 1446 ADTADQASGG----SRLG-HVDQSSGGAWAGTLD----QSGGGSKPRFENQTTEE---GS 1493
+ + +A G S+ G ++ + G+W + Q+G + E++T EE GS
Sbjct: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909
Query: 1494 WAGAG----GQAGGGSKVGPEDQSS--GRSWANSGDQISGGFLVGIVDQANGGSWTGAGH 1547
W G +AG PED SW S D+ + G
Sbjct: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDK----------------AIKETGT 953
Query: 1548 PASVGPKPIFEDQVSGRGSWADAREQV---------VGDSRLGLRDQSSGDSWAGTGDQA 1598
A+ KP E+ GSW +A ++V G L D++ SW GD+A
Sbjct: 954 VATCESKPENEEGAI-VGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEA 1012
Score = 66.6 bits (161), Expect = 3e-10
Identities = 124/580 (21%), Positives = 227/580 (39%), Gaps = 111/580 (19%)
Query: 155 AEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAG 214
AEI++ QV+ + G GAE+E + + +QA+ M GA P+ +S+ A
Sbjct: 4 AEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGAS 63
Query: 215 TLVMTEAVTLTEVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKR 274
T V T AV K+KA+ + + + +A+ WA + A+R
Sbjct: 64 TKVETSAVGGARPKSKAKAIPVSR------------------FKEEAQMWA-QPRFGAER 104
Query: 275 EAMTQTKAETHILAEKETEINRVMVTQSETLAVPREVA--------KMGATNKTGIVDET 326
+ T+ ++T+I+A + V+V +++ L+ RE+ + A + G +
Sbjct: 105 LSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGF--QP 162
Query: 327 KTRALEETVSVAKTQSEARPGATVDARGNPNGMSREVAGVDMKSCAQSQAVTKIQGDDM- 385
R+ EET S P T +PN D K +S + GD++
Sbjct: 163 SFRSKEET----NMGSWCCPRPTSKQEASPNS--------DFKWVDKSVSSLFWSGDEVT 210
Query: 386 ----PGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCK 441
PG V+D M+ E+ +R+ +++ +
Sbjct: 211 AKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIAS--------------------- 249
Query: 442 VGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTH 501
+G++ + P A+ + SG R D + SK + + ++ + +
Sbjct: 250 -SSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESW 308
Query: 502 AEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDML 561
A +AK +++ +AG +AN RA + + D G+ +V+ K
Sbjct: 309 FGAGKEAKFRSK------MRAGKEANNRARHRAKR-EACIDFMPGSIDVIKKE------- 354
Query: 562 SCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGM--AQSQGEALPNTRGK 619
SC P+ A+T S IK M KE A +A+ A+S+ EAL T
Sbjct: 355 SCFWPE----ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFW 410
Query: 620 ARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
A ++ M ++ ++ E+++ S + + A +K+ R
Sbjct: 411 ATDES----------SMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTD 460
Query: 680 GQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDS 719
G+ + G++L GA+ K T +K GA E T++S
Sbjct: 461 GERI------GDSLFGAREK------TSMKTGA-EATSES 487
>gi|103472136 G protein-coupled receptor associated sorting protein 1
[Homo sapiens]
Length = 1395
Score = 256 bits (653), Expect = 2e-67
Identities = 362/1510 (23%), Positives = 595/1510 (39%), Gaps = 256/1510 (16%)
Query: 981 KGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSV 1040
K VV A D +P+V +Q + +PGAR K K +M
Sbjct: 17 KPGEEVVGGAEIENDVPLVVRPKV--RTQAQIMPGARPKNKSK------------VMPGA 62
Query: 1041 QVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKV 1100
+V S G P +K K A+P + + AQP+ A S+T ++ +
Sbjct: 63 STKVETSAVGGARPKSKAK------AIPVSRFKEEAQMWAQPRFGAERLSKTERNSQTNI 116
Query: 1101 KGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEA 1160
+ + + A T++ ++ + + + E+ P + + + +++E
Sbjct: 117 IASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGFQPSFRSKEETNMGSWC 176
Query: 1161 EAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWIKF--RFQTMDGDWENS 1218
PTS+ E + + ++ +W+G V +K R M N+
Sbjct: 177 CPRPTSKQEASPNSDF-KWVDKSVSSLFWSGDEVTAKFHPGNRVKDSNRSMHMANQEANT 235
Query: 1219 VSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQ 1278
+S + E I S SG+ D++ + W A D+T+ +W+G R + +R+ +
Sbjct: 236 MSRSQTNQELYIASSSGSEDES-VKTPWFWARDKTN--TWSGPREDPN------SRSRFR 286
Query: 1279 ASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQAS---- 1334
+ ++ ++S G+ D +W GA +A S AG +A +
Sbjct: 287 SKKEVYV--ESSSGSEHEDHLE--SWFGAGKEAKFRSKMRAGKEANNRARHRAKREACID 342
Query: 1335 --DGS----------WPGGQASGVS--WVGEEAIGGSWTG----------------AENQ 1364
GS WP A+ S + +EA + T +E +
Sbjct: 343 FMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEE 402
Query: 1365 ASEGSWAGA----GAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGG------SKPRFEDQ 1414
A G+W A + +S+ V D++ GSW T +++ G S+PR + +
Sbjct: 403 ALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTDGE 462
Query: 1415 ASGEGSWAG-------AGGQASGGSMLGPED-QSSGRSWADTADQASGGSRLGHVDQSSG 1466
G+ + G +A+ S+L +D Q SW ++ + + +++
Sbjct: 463 RIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAGEEVNQEAE----EETIF 518
Query: 1467 GAWAGTLD----QSGGGSKPRFENQTTEE---GSWAGAGGQA------GGGSKVGPEDQS 1513
G+W +D +SG G ++ EE G W +G Q G ++ G E+++
Sbjct: 519 GSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEET 578
Query: 1514 SGRSWANSGDQI--------SGGFLVGIVDQANG-GSW----TGAGHPASVGPKPIFEDQ 1560
SW + +Q S + G ++ GSW A V K ED+
Sbjct: 579 IFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACVEGDVNSKSSLEDK 638
Query: 1561 VSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWF----CVCPGSQTNGGSWG 1616
A+E+V G+R + + T +++ W C+ P GGSW
Sbjct: 639 EEAMIPCFGAKEEVSMKHGTGVRCRFMAGA-EETNNKSCFWAEKEPCMYPAG---GGSWK 694
Query: 1617 GASGQDVGGSRPGPTNQSSAGSW------DSPGSQVSGSCW-TGAGAVDQAGGCSKPGFE 1669
SRP + SW P + + W T +D G +K E
Sbjct: 695 ---------SRP-EEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTE 744
Query: 1670 DQAI-GGGFWPGAGDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWA 1728
++ I FW ED++ ++ +RP + GSW
Sbjct: 745 EETIINSWFW--------------KEDEA-------ISEATDREESRPEAEEGDIIGSWF 783
Query: 1729 GTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGG-----GSWAGAGSQASGESWAGSRPGN 1783
W G D+ ++ ED+ GSW GA + R
Sbjct: 784 ----------WAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREETI------RREAG 827
Query: 1784 EAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEA---VIGSWCW 1840
S E++ GSW E+ S E A GF PG E +GSW W
Sbjct: 828 SCSKSSPKAEEEEVIIGSWFWEEE-------ASPEAVAGVGFESKPGTEEEEITVGSWFW 880
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
EE+A I +AG +A+ E E + GSW + G V
Sbjct: 881 PEEEASI----------------QAGSQAVEEMESETEEETIFGSWF------WDGKEVS 918
Query: 1901 AEAGAGAEAGAG------AEAGAGAGAEAGAEAG--AGAGAGPGTESGAGVWSWDGDATT 1952
EAG + E+ + +A E G A + P E GA V SW
Sbjct: 919 EEAGPCCVSKPEDDEEMIVESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDE 978
Query: 1953 VESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWA------ESENSNTF 2006
V++R G G S TLA D +E + S FWA ES S F
Sbjct: 979 VDNRTDNGSNCG--SRTLA--------------DEDEAIVGSWFWAGDEAHFESNPSPVF 1022
Query: 2007 RSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSES 2066
R+ S E + + E G W G + S + PK A E
Sbjct: 1023 RAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGPWGRVGFPSISPFRF-PKEAASLFCEM 1081
Query: 2067 RGIYPYMVPGAGMGSWDGAMIWSET---KFAHQSEASFPVEDESRKQTRTGEKTRPWSCR 2123
G P + + G +++ + +F Q + S+ E R+ R E T P S
Sbjct: 1082 FGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYDPSYRSVQEIREHLRAKESTEPESSS 1141
Query: 2124 C---KHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVI 2180
C + E + + E+L+ ++E DP +HEI+ A+ + ++ + +R+ G +S+I
Sbjct: 1142 CNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLI 1201
Query: 2181 ESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLI 2240
E+LLN P VR L + ++ N ++TY+ +VCE+T+ Y ++S QL+G+R+I
Sbjct: 1202 ETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTYICKVCEETLAYSVDSPEQLSGIRMI 1261
Query: 2241 RHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTS 2300
RHLT T++Y +V NY+S FL LL G+ +T+ HVL MLLN S+N MTK+LL A A +
Sbjct: 1262 RHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHVLKMLLNLSENLFMTKELLSAEAVSE 1321
Query: 2301 LINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLR 2360
I +F+++ET +NI L++FENI + K+ F+ D F+ L F + + AK+L+
Sbjct: 1322 FIGLFNREETNDNIQIVLAIFENIGNNIKKET-VFSDDDFNIEPLISAFHKVEKFAKELQ 1380
Query: 2361 ALAAECNDPE 2370
NDPE
Sbjct: 1381 GKTDNQNDPE 1390
Score = 78.2 bits (191), Expect = 9e-14
Identities = 216/1020 (21%), Positives = 372/1020 (36%), Gaps = 210/1020 (20%)
Query: 744 PNVVLKAEVGEGAMGTAQLQIM--ASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQ 801
P V +A++ GA + ++M AS+K E + K + A+ + + Q
Sbjct: 38 PKVRTQAQIMPGARPKNKSKVMPGASTKVETSAVGGARPKSKAKAIPVSRFKEEAQMWAQ 97
Query: 802 PQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANSQGEVLPGAKNKVK 861
P+ A + ++ I +P +S + T + + + N+ E P K +
Sbjct: 98 PRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQ 157
Query: 862 ANLNAV--SKAEAGMGATGSVQP----QAVANSHCETLPGAKNKVRGNWNAVS-KAGAGM 914
A SK E MG+ +P +A NS + + + + + + + V+ K G
Sbjct: 158 AGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDKSVSSLFWSGDEVTAKFHPGN 217
Query: 915 DTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLP 974
+ S + +AN + + ++++ + S +G+ +++V + P A + T
Sbjct: 218 RVKDSNRSMHMANQEANTM--SRSQTNQELYIASSSGSEDESVKT--PWFWARDKTNTWS 273
Query: 975 GARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKAEAGA 1034
G R S SK ++ ++ + E+ GA + K S + EA
Sbjct: 274 GPREDPNSRSRFRSKKEVYVESSSGSEHE----DHLESWFGAGKEAKFRSKMRAGKEANN 329
Query: 1035 GIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAG--------------------A 1074
+ + F +PG+ + ++ S P+ A A
Sbjct: 330 RARHRAKREACIDF----MPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKEEA 385
Query: 1075 DTVGSAQPQAVANSQSETLLG------------------ARNKVKGNTI------AVPKA 1110
T A+ + A S+ E L+G + +V+ +I +A
Sbjct: 386 KTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEEEA 445
Query: 1111 GTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAE------------------- 1151
G G ++P+ G++L GAR+K+ + AEAT+E
Sbjct: 446 SMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFWAG 505
Query: 1152 DEAYAKPEAE--------AMPTSESEGGSGTQACRKTQPN----IHDYYWNG--IGVEDW 1197
+E + E E + + E G G +T+ I ++W+G + +E
Sbjct: 506 EEVNQEAEEETIFGSWFWVIDAASVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAG 565
Query: 1198 IAAERWIKFRFQTMDGD--WENSVSWADDENEASIGSWSGASDKAGIIRSW----AVACD 1251
I E +T+ G W + ++ D E S + GA ++ II SW AC
Sbjct: 566 IGEEARPGAEEETIFGSWFWAENQTYMDCRAETSCDTMQGAEEEEPIIGSWFWTRVEACV 625
Query: 1252 ETSVKSWA-------------GARAENVVGIGTWARAGEQASGGLWAGGQTSEGT---WA 1295
E V S + GA+ E + GT R AG + + WA
Sbjct: 626 EGDVNSKSSLEDKEEAMIPCFGAKEEVSMKHGTGVRC------RFMAGAEETNNKSCFWA 679
Query: 1296 GDK-----ASGGAWTG--AENQASGGSWALAGNQAIGE------LWAAGQAS-DGSWPGG 1341
+ A GG+W E + SW + E LWA +++ DG+ G
Sbjct: 680 EKEPCMYPAGGGSWKSRPEEEEDIVNSWFWSRKYTKPEAIIGSWLWATEESNIDGT--GE 737
Query: 1342 QASGVSWVGEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSD 1401
+A ++ EE I SW E++A + A + A D G WAG D
Sbjct: 738 KAKLLT--EEETIINSWFWKEDEAI------SEATDREESRPEAEEGDIIGSWFWAGEED 789
Query: 1402 QSGGGSKPRFEDQASGE-----GSWAGA--------GGQASGGSMLGPEDQSSGRSW--- 1445
+ ++ R ED+ + E GSW GA G S S E++ SW
Sbjct: 790 RLEPAAETREEDRLAAEKEGIVGSWFGAREETIRREAGSCSKSSPKAEEEEVIIGSWFWE 849
Query: 1446 ADTADQASGG----SRLG-HVDQSSGGAWAGTLD----QSGGGSKPRFENQTTEE---GS 1493
+ + +A G S+ G ++ + G+W + Q+G + E++T EE GS
Sbjct: 850 EEASPEAVAGVGFESKPGTEEEEITVGSWFWPEEEASIQAGSQAVEEMESETEEETIFGS 909
Query: 1494 WAGAG----GQAGGGSKVGPEDQSS--GRSWANSGDQISGGFLVGIVDQANGGSWTGAGH 1547
W G +AG PED SW S D+ + G
Sbjct: 910 WFWDGKEVSEEAGPCCVSKPEDDEEMIVESWFWSRDK----------------AIKETGT 953
Query: 1548 PASVGPKPIFEDQVSGRGSWADAREQV---------VGDSRLGLRDQSSGDSWAGTGDQA 1598
A+ KP E+ GSW +A ++V G L D++ SW GD+A
Sbjct: 954 VATCESKPENEEGAI-VGSWFEAEDEVDNRTDNGSNCGSRTLADEDEAIVGSWFWAGDEA 1012
Score = 66.6 bits (161), Expect = 3e-10
Identities = 124/580 (21%), Positives = 227/580 (39%), Gaps = 111/580 (19%)
Query: 155 AEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAG 214
AEI++ QV+ + G GAE+E + + +QA+ M GA P+ +S+ A
Sbjct: 4 AEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQAQIMPGARPKNKSKVMPGAS 63
Query: 215 TLVMTEAVTLTEVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKR 274
T V T AV K+KA+ + + + +A+ WA + A+R
Sbjct: 64 TKVETSAVGGARPKSKAKAIPVSR------------------FKEEAQMWA-QPRFGAER 104
Query: 275 EAMTQTKAETHILAEKETEINRVMVTQSETLAVPREVA--------KMGATNKTGIVDET 326
+ T+ ++T+I+A + V+V +++ L+ RE+ + A + G +
Sbjct: 105 LSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDTESFPRRKAHYQAGF--QP 162
Query: 327 KTRALEETVSVAKTQSEARPGATVDARGNPNGMSREVAGVDMKSCAQSQAVTKIQGDDM- 385
R+ EET S P T +PN D K +S + GD++
Sbjct: 163 SFRSKEET----NMGSWCCPRPTSKQEASPNS--------DFKWVDKSVSSLFWSGDEVT 210
Query: 386 ----PGTGVEDMGNCKTMSRAESGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCK 441
PG V+D M+ E+ +R+ +++ +
Sbjct: 211 AKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIAS--------------------- 249
Query: 442 VGAGADVRACIQPQTVAKKQAEVTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTH 501
+G++ + P A+ + SG R D + SK + + ++ + +
Sbjct: 250 -SSGSEDESVKTPWFWARDKTNTWSGPREDPNSRSRFRSKKEVYVESSSGSEHEDHLESW 308
Query: 502 AEAMSDAKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDML 561
A +AK +++ +AG +AN RA + + D G+ +V+ K
Sbjct: 309 FGAGKEAKFRSK------MRAGKEANNRARHRAKR-EACIDFMPGSIDVIKKE------- 354
Query: 562 SCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGM--AQSQGEALPNTRGK 619
SC P+ A+T S IK M KE A +A+ A+S+ EAL T
Sbjct: 355 SCFWPE----ENANTFSRPMIKKEARARAMTKEEAKTKARARAKQEARSEEEALIGTWFW 410
Query: 620 ARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
A ++ M ++ ++ E+++ S + + A +K+ R
Sbjct: 411 ATDES----------SMADEASIESSLQVEDESIIGSWFWTEEEASMGTGASSKSRPRTD 460
Query: 680 GQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDS 719
G+ + G++L GA+ K T +K GA E T++S
Sbjct: 461 GERI------GDSLFGAREK------TSMKTGA-EATSES 487
>gi|29540566 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 236 bits (602), Expect = 2e-61
Identities = 117/253 (46%), Positives = 183/253 (72%), Gaps = 1/253 (0%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
+ P++L+K++C++EM+E P + E A AL N+A Y+++ +++R++GG+ ++ +LN P
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
V++KAL LNN+SV AEN R++K Y+NQVC+DT+T LNS+VQLAGLRL+ ++T+T+EY
Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ N IS+F RL + G+ ETK VL +LLN ++NP+MT++LL A P+SL ++F+KKE
Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE IL L +FENIN +FK TQ++F + SL+F + + CA K+ + + +D
Sbjct: 298 NKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESH-HDF 356
Query: 2370 EVKERVELLISKL 2382
VK +V ++KL
Sbjct: 357 LVKVKVGKFMAKL 369
Score = 55.8 bits (133), Expect = 5e-07
Identities = 25/43 (58%), Positives = 31/43 (72%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG ++VGWVTAGLVI AG CY IY+ T+GR Q+ +A GS
Sbjct: 1 MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGS 43
>gi|29540564 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 236 bits (602), Expect = 2e-61
Identities = 117/253 (46%), Positives = 183/253 (72%), Gaps = 1/253 (0%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
+ P++L+K++C++EM+E P + E A AL N+A Y+++ +++R++GG+ ++ +LN P
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
V++KAL LNN+SV AEN R++K Y+NQVC+DT+T LNS+VQLAGLRL+ ++T+T+EY
Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ N IS+F RL + G+ ETK VL +LLN ++NP+MT++LL A P+SL ++F+KKE
Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE IL L +FENIN +FK TQ++F + SL+F + + CA K+ + + +D
Sbjct: 298 NKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESH-HDF 356
Query: 2370 EVKERVELLISKL 2382
VK +V ++KL
Sbjct: 357 LVKVKVGKFMAKL 369
Score = 55.8 bits (133), Expect = 5e-07
Identities = 25/43 (58%), Positives = 31/43 (72%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG ++VGWVTAGLVI AG CY IY+ T+GR Q+ +A GS
Sbjct: 1 MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGS 43
>gi|7705274 armadillo repeat containing, X-linked 3 [Homo sapiens]
Length = 379
Score = 236 bits (602), Expect = 2e-61
Identities = 117/253 (46%), Positives = 183/253 (72%), Gaps = 1/253 (0%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
+ P++L+K++C++EM+E P + E A AL N+A Y+++ +++R++GG+ ++ +LN P
Sbjct: 118 LSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAKILNTRDP 177
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
V++KAL LNN+SV AEN R++K Y+NQVC+DT+T LNS+VQLAGLRL+ ++T+T+EY
Sbjct: 178 IVKEKALIVLNNLSVNAENQRRLKVYMNQVCDDTITSRLNSSVQLAGLRLLTNMTVTNEY 237
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ N IS+F RL + G+ ETK VL +LLN ++NP+MT++LL A P+SL ++F+KKE
Sbjct: 238 QHMLANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMTRELLRAQVPSSLGSLFNKKE 297
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE IL L +FENIN +FK TQ++F + SL+F + + CA K+ + + +D
Sbjct: 298 NKEVILKLLVIFENINDNFKWEENEPTQNQFGEGSLFFFLKEFQVCADKVLGIESH-HDF 356
Query: 2370 EVKERVELLISKL 2382
VK +V ++KL
Sbjct: 357 LVKVKVGKFMAKL 369
Score = 55.8 bits (133), Expect = 5e-07
Identities = 25/43 (58%), Positives = 31/43 (72%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG ++VGWVTAGLVI AG CY IY+ T+GR Q+ +A GS
Sbjct: 1 MGYARKVGWVTAGLVIGAGACYCIYRLTRGRKQNKEKMAEGGS 43
>gi|7706143 armadillo repeat containing, X-linked 1 [Homo sapiens]
Length = 453
Score = 224 bits (570), Expect = 1e-57
Identities = 157/483 (32%), Positives = 256/483 (53%), Gaps = 41/483 (8%)
Query: 1910 GAGAEAGAGAGAEAGAEAGAGA-----GAGPGTESGAGVWSWDGDATT-----VESRLGA 1959
G EAG A AG GAGA G + +W D ++T VE+ GA
Sbjct: 2 GRTREAGCVA---AGVVIGAGACYCVYRLAWGRDENEKIWDEDEESTDTSEIGVETVKGA 58
Query: 1960 GEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWAESENSNTFRSKSGKDASFESG 2019
AG S A+ G+ E+ E S +E+ E +++ S SG ++
Sbjct: 59 KTNAGAGSG--AKLQGDSEVKPEVSLGLEDCP------GVKEKAHS-GSHSGGGLEAKAK 109
Query: 2020 AGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGAGM 2079
A NT +K++ A G +GN + P + +R G
Sbjct: 110 ALFNT-LKEQASAKAGKGARVGTISGNRTLAPSLPCPGGRGGGCHPTRS--GSRAGGRAS 166
Query: 2080 GSWDGAMIWSETKFAHQSEASFPVEDESRKQTRTGEKTRPWSCRCKHEANMDPRDLEKLI 2139
G G + +K ++PV R G+ P+ K + + DL+K++
Sbjct: 167 GKSKGK---ARSKSTRAPATTWPV--------RRGKFNFPY----KIDDILSAPDLQKVL 211
Query: 2140 CMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYPSVRQKALNAL 2199
++E T DP + E+A L N+A YS++ +R +GG+ +I L+ P +R+K NAL
Sbjct: 212 NILERTNDPFIQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTKDPIIREKTYNAL 271
Query: 2200 NNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVTNYISE 2259
NN+SV AEN K+KTY++QVC+DT+ L+S VQ+AGLRL+ ++T+T+ YQH+++ +
Sbjct: 272 NNLSVNAENQGKIKTYISQVCDDTMVCRLDSAVQMAGLRLLTNMTVTNHYQHLLSYSFPD 331
Query: 2260 FLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKETKENILNALS 2319
F LL +G+ TK ++ +++NF++NP+MT++L+ P+ LI++F+K+ +E +LN L+
Sbjct: 332 FFALLFLGNHFTKIQIMKLIINFTENPAMTRELVSCKVPSELISLFNKEWDREILLNILT 391
Query: 2320 LFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDPEVKERVELLI 2379
LFENIN + K A ++ +FS++SL+FLF+ C KK++ALA ND VK +V ++
Sbjct: 392 LFENINDNIKNEGLASSRKEFSRSSLFFLFKESGVCVKKIKALANH-NDLVVKVKVLKVL 450
Query: 2380 SKL 2382
+KL
Sbjct: 451 TKL 453
Score = 60.1 bits (144), Expect = 3e-08
Identities = 45/143 (31%), Positives = 74/143 (51%), Gaps = 20/143 (13%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTL-----ARNGSTVKMETVVGVQS 147
MGR +E G V AG+VI AG CY +Y+ GR ++ + + + S + +ETV G ++
Sbjct: 1 MGRTREAGCVAAGVVIGAGACYCVYRLAWGRDENEKIWDEDEESTDTSEIGVETVKGAKT 60
Query: 148 QTLAINEAEI----KTKPQVEIG----------AETGARSGPGAEVETKATAIAIHRANS 193
A + A++ + KP+V +G A +G+ SG G E + KA + + +
Sbjct: 61 NAGAGSGAKLQGDSEVKPEVSLGLEDCPGVKEKAHSGSHSGGGLEAKAKALFNTL-KEQA 119
Query: 194 QAKAMVGAEPETQSESKVVAGTL 216
AKA GA T S ++ +A +L
Sbjct: 120 SAKAGKGARVGTISGNRTLAPSL 142
>gi|41054846 armadillo repeat containing, X-linked 5 [Homo sapiens]
Length = 558
Score = 220 bits (560), Expect = 1e-56
Identities = 169/556 (30%), Positives = 277/556 (49%), Gaps = 57/556 (10%)
Query: 1883 SGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAG 1942
SG+ R+ A G G A A +A A A AE E+ A AG G +
Sbjct: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTH 63
Query: 1943 VWSW-DGDATT---------------VESRLGAGEEAGVESWTLARNVGEDELSRESSPD 1986
++ + A T VE++ E + T ++ + +S + +
Sbjct: 64 TVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSE 123
Query: 1987 IE-----EISLRSLFWAESENSNTFRSKSGKDASF--ESGAGDNTSIKDKFEAAGGVDIG 2039
++ E ++RS + + + R ++ S +S D +I F +G
Sbjct: 124 VKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVG 183
Query: 2040 SWFCAGNENTSED-KSAPKA--------------KAKKSSESRGIYPYMVPGAG------ 2078
SWF E + + K PK K K + SR Y +VP G
Sbjct: 184 SWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQSLP 243
Query: 2079 -MGSWDGAMIWSETKFAHQSEASFPVED--------ESRKQTRTGEK--TRPWSCRCKHE 2127
G+W ET + P E +KQ R EK P +C CK
Sbjct: 244 PEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSR 303
Query: 2128 A-NMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNN 2186
+++P++ +KL+ ++++T+DP +HEIA + S Y ++ +++ +VG +IE+L+NN
Sbjct: 304 GFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNN 363
Query: 2187 PYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTIT 2246
P AL+ +++ S ++E + ++Y++QVC+ ++ PLNS VQLAGL+L+ HL+I
Sbjct: 364 PNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIK 423
Query: 2247 SEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFS 2306
E +++T+YI +FL LL GS +TK +VL + SKN + T++L+ A +SL+ F+
Sbjct: 424 FEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFN 483
Query: 2307 KKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAEC 2366
K E+K NILN + +FENIN+ FK +AK FT++KF+K+ L +FQ K +KL+ L AE
Sbjct: 484 KNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDL-AEH 542
Query: 2367 NDPEVKERVELLISKL 2382
+DPEV+++V LI KL
Sbjct: 543 SDPEVRDKVIRLILKL 558
Score = 54.7 bits (130), Expect = 1e-06
Identities = 43/116 (37%), Positives = 59/116 (50%), Gaps = 9/116 (7%)
Query: 238 EAVTQTDAEAGKI--VKKEAVTQTKAKAWA-LVAKTEAKREAMTQTKAETHILAEKETEI 294
EA + AEAG + A + K A VA+ E K E++TQ KA + T
Sbjct: 7 EARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHT-- 64
Query: 295 NRVMVTQSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATV 350
VT E +AV REV K+ T KT ++ ETKT+ L E V +T+S+A P + V
Sbjct: 65 ----VTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRV 116
Score = 48.1 bits (113), Expect = 1e-04
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 15/140 (10%)
Query: 163 VEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVA----GTLVM 218
V+ G E AR A ++ + A R N + +A AE E ++ES A G +
Sbjct: 2 VDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTR 61
Query: 219 TEAVTLTEVKAKAREVAMKEAVTQT----DAEAGKIVKKEAVTQTKAKAWALVAKTEAKR 274
T VT E A REV E T+T + + + ++ V QTK+KA +
Sbjct: 62 THTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPM-------S 114
Query: 275 EAMTQTKAETHILAEKETEI 294
T TK+E ++A E I
Sbjct: 115 RVSTVTKSEVKVVAVIEANI 134
Score = 42.7 bits (99), Expect = 0.004
Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 18/178 (10%)
Query: 1024 SNAISKAEAGA--GIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQ 1081
+ A KAEAG GI G +V Q E + A+ K + +V +A+AG A
Sbjct: 8 ARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELK----TESVTQAKAG----DGAM 59
Query: 1082 PQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSM 1141
+ + E + R +K + T+ A+ IV ++ + +P +R ++
Sbjct: 60 TRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTV 119
Query: 1142 STSEAEATAEDEA----YAKPEAEA----MPTSESEGGSGTQACRKTQPNIHDYYWNG 1191
+ SE + A EA YAK +A P E G ++ + + NI ++W G
Sbjct: 120 TKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTG 177
Score = 39.7 bits (91), Expect = 0.036
Identities = 22/60 (36%), Positives = 32/60 (53%)
Query: 1832 EAVIGSWCWTEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEE 1891
EA I S+ + +KA+ SRPD ++E + +S +E ICS + S GSW EE
Sbjct: 131 EANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEE 190
Score = 38.5 bits (88), Expect = 0.080
Identities = 20/55 (36%), Positives = 27/55 (49%)
Query: 1793 SEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKADI 1847
S D+A GS ++ S + S E E N WF G E +GSW W EE+ +
Sbjct: 140 SHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSL 194
Score = 37.7 bits (86), Expect = 0.14
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 143 VGVQSQTLAINEAEIKTKPQVEIGAETGARSGPGAEVETKATAIAIHRANSQAKAMVGAE 202
V ++Q A+ EAE+KT+ + T A++G GA T+ + A + + ++ E
Sbjct: 30 VNGKTQAEAVAEAELKTE------SVTQAKAGDGA--MTRTHTVTYREAMAVTREVIKVE 81
Query: 203 PETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAVTQTDAEAGKIVKKEAVTQTKAK 262
T++ V T + E + + K+KA ++ VT+++ + +++ + K+
Sbjct: 82 DTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSH 141
Query: 263 AWALVAKTEAKRE 275
A +RE
Sbjct: 142 DKANTGSRPDRRE 154
Score = 32.3 bits (72), Expect = 5.7
Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 22/182 (12%)
Query: 506 SDAKVKNRGNPNAMTKAG----AKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDML 561
S + + RG A + G A A + +Q EA+ +A K+ AK GDG
Sbjct: 4 SGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESV--TQAKAGDG---- 57
Query: 562 SCTQPQLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKAR 621
+ T+ V +A ++ IKV T V+ K + +A+ +P T+ KA
Sbjct: 58 AMTRTHTVTYREAMAVTREVIKVEDTTKTR----VMVETKTKPLAER--SIVPQTKSKAM 111
Query: 622 GKAKAKCKTGPGMDMKTCTQPQAGVKTPA----EALLDSRVDGRGNPNATSKAGTKADQR 677
++ T ++K +A +++ A +A SR D R + K+ + ++
Sbjct: 112 PMSRVSTVT--KSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEEN 169
Query: 678 VC 679
+C
Sbjct: 170 IC 171
>gi|51702248 G protein-coupled receptor associated sorting protein 2
[Homo sapiens]
Length = 838
Score = 218 bits (555), Expect = 6e-56
Identities = 222/840 (26%), Positives = 359/840 (42%), Gaps = 117/840 (13%)
Query: 1608 SQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCS--K 1665
+Q G+ + V +RP Q+ +G+ QV G GA +A G + +
Sbjct: 42 TQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMG----GARPKTEAQGITGAR 97
Query: 1666 PGFEDQAIGGGFWPGAGDQTGG----GSRPGSEDQSSGIGSWGV-------------AGG 1708
P + +A+GG A +T G+RP E Q+ +G A
Sbjct: 98 PKTDARAVGG-----ARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVA 152
Query: 1709 QVLGGARPGPADQSSGGS------------WAGTGNQSSGRSWIGPGDQ----AVDCSKP 1752
L A G +S G S + GT Q + W GPG++ + S+P
Sbjct: 153 WPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRP 212
Query: 1753 EFEDQACG-GGSWAGAGSQASGESWAGS------------------RPGNEAIGGSRMGS 1793
++A G W+ + + W G R ++ SR S
Sbjct: 213 RAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRS 272
Query: 1794 EDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGA--EAVIGSWCWTEEKADIVSRP 1851
+ +A SW+ SED+AS F SF V N F P EA I S T + S
Sbjct: 273 KQEAYVDSWSGSEDEASNPF--SFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESES 330
Query: 1852 DDK----------DEATTASRSRAGEEAMICSRIEAENKASSG---SWIRSEEVAYMGSC 1898
+D+ +EA + R R E+ ++ A+ S R EE +GS
Sbjct: 331 EDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSW 390
Query: 1899 VGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLG 1958
AE A E GA A + G E GA G+ A + GA E++
Sbjct: 391 FWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGA--------VAREEAKPE 442
Query: 1959 AGEEAGVESWTLARNVGEDELSRESSP-DIEEISLRSLFWAESENSNTFRSKSGKDASFE 2017
+ EEA SW R DE + +P + ++S R AE N+++ R ++ + + E
Sbjct: 443 SEEEAIFGSWFWDR----DEACFDLNPCPVYKVSDRFRDAAEELNASS-RPQTWDEVTVE 497
Query: 2018 SGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGA 2077
G + + + G+ E SE A + S E + P
Sbjct: 498 FKPGLFHGVGFRSTSPFGIP---------EEASEMLEAKPKNLELSPEGEEQESLLQPDQ 548
Query: 2078 GMGSWDGAMIWSETKFAHQSEASFPVEDESRKQTRTGE--KTRPWSCRC-KHEANMDPRD 2134
+F Q + S+ E R+ R E ++ WSC C + E + +
Sbjct: 549 -----------PSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEE 597
Query: 2135 LEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYPSVRQK 2194
E+ + +++ DP +HEI+ A+ + ++ + +R+ G +S+IE+LLN P VR
Sbjct: 598 FEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTS 657
Query: 2195 ALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVT 2254
L + +++ N ++T++ QVCE+T+ + ++S QL G+R++RHLT+T +Y ++
Sbjct: 658 FLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIA 717
Query: 2255 NYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKETKENI 2314
NY+S FL LLT + TK HVL MLLN S+NP++ K L A A + + +F+ +ET +NI
Sbjct: 718 NYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNI 777
Query: 2315 LNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDPEVKER 2374
+ +F+NI+ K + D FS L F+ + AK+L+A NDPEV ++
Sbjct: 778 QIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQ 837
Score = 66.6 bits (161), Expect = 3e-10
Identities = 128/516 (24%), Positives = 189/516 (36%), Gaps = 133/516 (25%)
Query: 1427 QASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFEN 1486
QA+ G+ E +S + T QA G+R Q GGA T Q G++P+
Sbjct: 43 QATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPK--- 99
Query: 1487 QTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGA- 1545
T+ + GA + + G + ++WA S F V QA G S T A
Sbjct: 100 --TDARAVGGARSKTDAKAIPGARPKDEAQAWAQS------EFGTEAVSQAEGVSQTNAV 151
Query: 1546 GHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRL--GLRDQSSGDSWAGTGDQASGWFC 1603
P + V+ + RE V D+ G + Q W G
Sbjct: 152 AWPLATAE----SGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFG---------- 197
Query: 1604 VCPGSQTNGGSWGGASGQDVGGSRPGPTNQSS--AGSWDSPGSQVSGSCWTGAGAVDQAG 1661
PG +TN GSW SRP ++S +G W + + + S WTG ++
Sbjct: 198 --PGEETNMGSW--------CYSRPRAREEASNESGFWSADETSTASSFWTG----EETS 243
Query: 1662 GCSKPGFEDQAIGGGFWPGAGDQTGGGSRP------------GSEDQSSGIGSWGVAGGQ 1709
S P E A QT SRP GSED++S S+ V G
Sbjct: 244 VRSWPREESNTRSR---HRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV-GEN 299
Query: 1710 VLGGARPGPADQSSGGSWAGTGNQSS----------GRSWIGPGDQA------------- 1746
RP ++++ S T + +SW+ PG++A
Sbjct: 300 TNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPN 359
Query: 1747 ----------VDCSK----PEFEDQACGGGSWAGAGSQASGESWAG----SRPGNE--AI 1786
VD + P FE++ GSW A +AS E A S PG E AI
Sbjct: 360 TALKLRAQKDVDSDRVKQEPRFEEEVI-IGSWFWAEKEASLEGGASAICESEPGTEEGAI 418
Query: 1787 GGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKAD 1846
GGS +E++++ G+ AR E + E+ E EA+ GSW W ++A
Sbjct: 419 GGSAYWAEEKSSLGAVAREEAKP----------ESEE--------EAIFGSWFWDRDEAC 460
Query: 1847 IVSRP-----------DDKDEATTASRSRAGEEAMI 1871
P D +E +SR + +E +
Sbjct: 461 FDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV 496
Score = 59.7 bits (143), Expect = 3e-08
Identities = 118/541 (21%), Positives = 198/541 (36%), Gaps = 102/541 (18%)
Query: 965 LASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNS 1024
+ ++ E A+ + K V++ D +P+V + P K +
Sbjct: 1 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
Query: 1025 NAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQA 1084
++A+A +G +VQV+ + K + +G + A PK +A A VG A+
Sbjct: 61 RPKTEAQAMSGARPKTEVQVMGGAR------PKTEAQGITGARPKTDARA--VGGAR--- 109
Query: 1085 VANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTS 1144
+ + ++ + GAR K + A + GT A +Q + V+ + P A +S S +
Sbjct: 110 -SKTDAKAIPGARPKDEAQAWAQSEFGTEA----VSQAEGVSQTNAVAWPLATAESGSVT 164
Query: 1145 EAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWI 1204
+++ + D +AE P GTQ + QP W G G E + + W
Sbjct: 165 KSKGLSMDRELVNVDAETFP--------GTQGQKGIQP------WFGPGEETNMGS--WC 208
Query: 1205 KFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSW------ 1258
R + + S W+ DE + W+G +ETSV+SW
Sbjct: 209 YSRPRAREEASNESGFWSADETSTASSFWTG---------------EETSVRSWPREESN 253
Query: 1259 --AGARAENVVGIGTWARAGEQASGGLWAGGQTSEGT----WAGDKASGGAWTGAENQAS 1312
+ RA++ + R+ ++A W+G + W G+ + +A+
Sbjct: 254 TRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEAN 313
Query: 1313 GGSWALAGNQAIGELWAAGQASDGSW--PGGQASG------------------------- 1345
S + E + + SW PG +A+
Sbjct: 314 IRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSD 373
Query: 1346 ----VSWVGEEAIGGSWTGAENQAS-EGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTS 1400
EE I GSW AE +AS EG GA A S G + G WA
Sbjct: 374 RVKQEPRFEEEVIIGSWFWAEKEASLEG---GASAICESEPGTEEGAI--GGSAYWAEEK 428
Query: 1401 DQSGG----GSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGS 1456
G +KP E++A GSW +A P + S R + D A++ + S
Sbjct: 429 SSLGAVAREEAKPESEEEAI-FGSWFWDRDEACFDLNPCPVYKVSDR-FRDAAEELNASS 486
Query: 1457 R 1457
R
Sbjct: 487 R 487
Score = 59.7 bits (143), Expect = 3e-08
Identities = 120/551 (21%), Positives = 206/551 (37%), Gaps = 110/551 (19%)
Query: 1073 GADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGET 1132
GA+ SAQ + + E + G + + PK T A T A+P+ S
Sbjct: 3 GAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATT--GARPKTETKSVPAA 60
Query: 1133 LPGARDKSMSTSEAEATAEDEAYAKPEAEAM------PTSESE--GGSGTQACRKTQPNI 1184
P ++MS + + + A+P+ EA P +++ GG+ ++ K P
Sbjct: 61 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIP-- 118
Query: 1185 HDYYWNGIGVEDWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAG-II 1243
G A+ W + F T +VS A+ ++ + +W A+ ++G +
Sbjct: 119 --------GARPKDEAQAWAQSEFGT------EAVSQAEGVSQTNAVAWPLATAESGSVT 164
Query: 1244 RSWAVACDETSV----KSWAGARAENVVGIGTWARAGEQASGGLWAGGQ--------TSE 1291
+S ++ D V +++ G + + GI W GE+ + G W +
Sbjct: 165 KSKGLSMDRELVNVDAETFPGTQGQK--GIQPWFGPGEETNMGSWCYSRPRAREEASNES 222
Query: 1292 GTWAGDKASGGA--WTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASGVSWV 1349
G W+ D+ S + WTG E SW + A Q + S P +
Sbjct: 223 GFWSADETSTASSFWTGEETSVR--SWPREESNTRSRHRAKHQTNPRSRPRSK------- 273
Query: 1350 GEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKP 1409
+EA SW+G+E++AS + S+W G + + +P
Sbjct: 274 -QEAYVDSWSGSEDEAS------------NPFSFWVG--------------ENTNNLFRP 306
Query: 1410 RFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGA- 1468
R ++A+ ED+ +SW ++A+ SR H D+
Sbjct: 307 RVREEANIRSKLRTNREDCFESE---SEDEFYKQSWVLPGEEAN--SRFRHRDKEDPNTA 361
Query: 1469 ----WAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQA---GGGSKV-----GPEDQSSGR 1516
+D +PRFE + GSW A +A GG S + G E+ + G
Sbjct: 362 LKLRAQKDVDSDRVKQEPRFEEEVI-IGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420
Query: 1517 S--WANSGDQISG----GFLVGIVDQANGGSWTGAGHPA--SVGPKPIFEDQVSGRGSWA 1568
S WA + ++A GSW A + P P++ +VS R +
Sbjct: 421 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVY--KVSDR--FR 476
Query: 1569 DAREQVVGDSR 1579
DA E++ SR
Sbjct: 477 DAAEELNASSR 487
Score = 59.7 bits (143), Expect = 3e-08
Identities = 88/386 (22%), Positives = 141/386 (36%), Gaps = 60/386 (15%)
Query: 1390 QAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTA 1449
Q GG+ T Q G++P+ + +A G GA + ++ G + ++WA +
Sbjct: 79 QVMGGARPKTEAQGITGARPKTDARAVG-----GARSKTDAKAIPGARPKDEAQAWAQSE 133
Query: 1450 DQASGGSRLGHVDQSSGGAW------AGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGG 1503
S+ V Q++ AW +G++ +S G S R E + ++ G GQ G
Sbjct: 134 FGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDR-ELVNVDAETFPGTQGQKGI 192
Query: 1504 GSKVGPEDQSSGRSWANSGDQI------SGGFLVGIVDQANGGSWTGAGHPASVGPKPIF 1557
GP ++++ SW S + GF WTG SV P
Sbjct: 193 QPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTG--EETSVRSWPRE 250
Query: 1558 EDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGG 1617
E R A+ Q SR + ++ DSW+G+ D+AS F G TN +
Sbjct: 251 ESNTRSRHR---AKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTN-NLFRP 306
Query: 1618 ASGQDVGGSRPGPTNQSSA-----------GSWDSPGSQVSGSC-------------WTG 1653
++ TN+ SW PG + +
Sbjct: 307 RVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRA 366
Query: 1654 AGAVDQAGGCSKPGFEDQA-IGGGFWPGAGDQTGGG------SRPGSEDQSSGIGSWGVA 1706
VD +P FE++ IG FW GG S PG+E+ + G ++
Sbjct: 367 QKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAE 426
Query: 1707 GGQVLGG-----ARPGPADQSSGGSW 1727
LG A+P +++ GSW
Sbjct: 427 EKSSLGAVAREEAKPESEEEAIFGSW 452
Score = 55.5 bits (132), Expect = 6e-07
Identities = 107/470 (22%), Positives = 185/470 (39%), Gaps = 62/470 (13%)
Query: 911 GAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQR 970
GA ++ A+P+ A + P +N V P VV + T G+ ++
Sbjct: 3 GAEIEPSAQAKPEKKAGEEVIAGPERENDV---PLVVRPKVRTQATTGARP-----KTET 54
Query: 971 ETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKA 1030
+++P AR K + + ++ MG A+P+ A P + G + + + A
Sbjct: 55 KSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDA 114
Query: 1031 EA--GAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTV----GSAQPQA 1084
+A GA Q + F E + A+ + N+ A P A A + +V G + +
Sbjct: 115 KAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRE 174
Query: 1085 VANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTS 1144
+ N +ET G + + P T G+ ++P+ + E+ + D++ ST+
Sbjct: 175 LVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADET-STA 233
Query: 1145 EAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWI 1204
+ T E+ + + P ES S +A +T P V+ W +E
Sbjct: 234 SSFWTGEETS-----VRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEA 288
Query: 1205 KFRFQTMDGDWENSVSWADDENEASIGS---------WSGASDKAGIIRSWAVACDE--- 1252
F G+ N++ EA+I S + S+ +SW + +E
Sbjct: 289 SNPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANS 348
Query: 1253 -----------TSVKSWA-----------GARAENVVGIGTWARAGEQAS--GGLWAGGQ 1288
T++K A R E V IG+W A ++AS GG A +
Sbjct: 349 RFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICE 408
Query: 1289 TSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSW 1338
+ GT G A GG+ AE ++S G A+A +A E + +A GSW
Sbjct: 409 SEPGTEEG--AIGGSAYWAEEKSSLG--AVAREEAKPE--SEEEAIFGSW 452
Score = 52.4 bits (124), Expect = 5e-06
Identities = 65/265 (24%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1842 EEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGA 1901
E +V RP + +ATT +R + +++ +R + E +A SG+ ++E G+
Sbjct: 29 ENDVPLVVRPKVRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKT 88
Query: 1902 EAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGE 1961
EA A +A A GA + +A A GA P E+ A W+ T S+
Sbjct: 89 EAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQA--WAQSEFGTEAVSQAEGVS 146
Query: 1962 EAGVESWTLA-RNVGEDELSRESSPDIEEISLRS-------------LFWAESENSNT-- 2005
+ +W LA G S+ S D E +++ + ++ E +N
Sbjct: 147 QTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGS 206
Query: 2006 ---FRSKSGKDASFESG--AGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKA 2060
R ++ ++AS ESG + D TS F + SW S +S +AK
Sbjct: 207 WCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSW----PREESNTRSRHRAKH 262
Query: 2061 KKSSESRGIYPYMVPGAGMGSWDGA 2085
+ + SR P A + SW G+
Sbjct: 263 QTNPRSR---PRSKQEAYVDSWSGS 284
Score = 50.8 bits (120), Expect = 2e-05
Identities = 77/270 (28%), Positives = 120/270 (44%), Gaps = 41/270 (15%)
Query: 127 VRTLARNGSTVKMET----VVGVQSQTLAINEAEIKTKPQVEIGA--ETGARSGPGAEVE 180
VRT A G+ K ET +++ A++ A KT+ QV GA +T A+ GA +
Sbjct: 40 VRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPK 99
Query: 181 TKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAV 240
T A A+ R+ + AKA+ GA P+ E++ A + TEAV+ E V
Sbjct: 100 TDARAVGGARSKTDAKAIPGARPK--DEAQAWAQSEFGTEAVS------------QAEGV 145
Query: 241 TQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVT 300
+QT+A A + E+ + TK+K ++ RE + AET + + I
Sbjct: 146 SQTNAVAWPLATAESGSVTKSKGLSM------DRE-LVNVDAETFPGTQGQKGIQPWFGP 198
Query: 301 QSET----LAVPREVAKMGATNKTGI--VDETKTRAL----EETV--SVAKTQSEARPGA 348
ET R A+ A+N++G DET T + EET S + +S R
Sbjct: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
Query: 349 TVDARGNPNG--MSREVAGVDMKSCAQSQA 376
+ NP S++ A VD S ++ +A
Sbjct: 259 RAKHQTNPRSRPRSKQEAYVDSWSGSEDEA 288
Score = 48.5 bits (114), Expect = 8e-05
Identities = 54/235 (22%), Positives = 95/235 (40%), Gaps = 15/235 (6%)
Query: 176 GAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVA 235
GAE+E A A + +A V A PE +++ +V V T+A T K + + V
Sbjct: 3 GAEIEPSAQA----KPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVP 58
Query: 236 MKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEIN 295
T+ A +G K E A+ KTEA+ + K + + ++ +
Sbjct: 59 AARPKTEAQAMSGARPKTEVQVMGGAR-----PKTEAQGITGARPKTDARAVGGARSKTD 113
Query: 296 RVMVTQSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATVDARGN 355
+ A P++ A+ A ++ G ++ + +T +VA + A G+ ++G
Sbjct: 114 AKAIPG----ARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKG- 168
Query: 356 PNGMSREVAGVDMKSCAQSQAVTKIQGDDMPGTGVEDMGNCKTMSRAESGADTRA 410
M RE+ VD ++ +Q IQ PG C + RA A +
Sbjct: 169 -LSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNES 222
Score = 38.9 bits (89), Expect = 0.061
Identities = 111/552 (20%), Positives = 192/552 (34%), Gaps = 106/552 (19%)
Query: 791 GAGTDTTGSVQPQIVANSQGEVLPGAKN--------KIRGNPTTVPNSGVGPYTTDSARP 842
GA + + +P+ A + P +N K+R TT + +ARP
Sbjct: 3 GAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAARP 62
Query: 843 QAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCET----LPGAKN 898
+ A + P + +V ++A+ GA +AV + +T +PGA+
Sbjct: 63 KTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARP 122
Query: 899 KVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVG 958
K A S+ G T +Q + V+ + P A +++G+ + G
Sbjct: 123 KDEAQAWAQSEFG----TEAVSQAEGVSQTNAVAWPLA----------TAESGSVTKSKG 168
Query: 959 STQPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDT-MGSAQPQVVANSQRETLPGAR 1017
+ + L + ET PG +G + G E+T MG S + P AR
Sbjct: 169 LSMDRELVNVDAETFPG----TQGQKGIQPWFGPGEETNMG---------SWCYSRPRAR 215
Query: 1018 NKVKGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTV 1077
+ S G + + +SF ++ R SN + A T
Sbjct: 216 EEASNES----------GFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTN 265
Query: 1078 GSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGAR 1137
++P++ + ++ G+ ++ G T + +P++ R
Sbjct: 266 PRSRPRSKQEAYVDSWSGSEDEASNPF----SFWVGENTNNLFRPRV------REEANIR 315
Query: 1138 DKSMSTSE--AEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVE 1195
K + E E+ +EDE Y ++ +P E+ S + K PN
Sbjct: 316 SKLRTNREDCFESESEDEFY--KQSWVLPGEEA--NSRFRHRDKEDPNTA---------- 361
Query: 1196 DWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSV 1255
+K R Q D D + E E IGSW A E S+
Sbjct: 362 --------LKLRAQ-KDVDSDRVKQEPRFEEEVIIGSWFWAE-------------KEASL 399
Query: 1256 KSWAGARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGS 1315
+ A A E+ G G WA ++S G A ++A +E +A GS
Sbjct: 400 EGGASAICESEPG----TEEGAIGGSAYWAEEKSSLGAVAREEAK----PESEEEAIFGS 451
Query: 1316 WALAGNQAIGEL 1327
W ++A +L
Sbjct: 452 WFWDRDEACFDL 463
Score = 38.5 bits (88), Expect = 0.080
Identities = 85/413 (20%), Positives = 154/413 (37%), Gaps = 49/413 (11%)
Query: 397 KTMSRAESGADTRASAQPQIFAKTQTEA--IPGA--KIDAGGNTNAMCKVGAGADVRACI 452
KT ++A SGA + Q A+ +TEA I GA K DA A K A A A
Sbjct: 63 KTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARP 122
Query: 453 QPQTVAKKQAEVTSGA--RVDGRGNTNVISKAITGADMRAAAQPQAVASTHAEAMSDAKV 510
+ + A Q+E + A + +G TN ++ + A+ + + + ++ DA+
Sbjct: 123 KDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAET 182
Query: 511 --KNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLSCTQPQL 568
+G G S + P AR+++
Sbjct: 183 FPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFW----------------- 225
Query: 569 VASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKC 628
++ + T S +V + P+E + + + Q+ N R + R K +A
Sbjct: 226 -SADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQT------NPRSRPRSKQEAYV 278
Query: 629 KTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVCGQPLVVANP 688
+ G + + V L RV R N SK T + +
Sbjct: 279 DSWSGSEDEASNPFSFWVGENTNNLFRPRV--REEANIRSKLRTNREDCFESESEDEFYK 336
Query: 689 QGEALPGA------KNKVKGNPHTVLKVGAGEGTTDSAQPEAVVSFQGEALLGT------ 736
Q LPG +++ K +P+T LK+ A + DS + + F+ E ++G+
Sbjct: 337 QSWVLPGEEANSRFRHRDKEDPNTALKLRA-QKDVDSDRVKQEPRFEEEVIIGSWFWAEK 395
Query: 737 KNKVKGNPNVVLKAEVG--EGAMGTAQLQIMASSKGEALLDSKNKVKGNSNAV 787
+ ++G + + ++E G EGA+G + S A+ + K + A+
Sbjct: 396 EASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAI 448
Score = 34.3 bits (77), Expect = 1.5
Identities = 55/224 (24%), Positives = 88/224 (39%), Gaps = 44/224 (19%)
Query: 404 SGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCKVGAGADVRACIQPQTVAKKQAE 463
+GA+ SAQ + K E I G + + DV ++P K + +
Sbjct: 2 TGAEIEPSAQAKPEKKAGEEVIAGPEREN--------------DVPLVVRP----KVRTQ 43
Query: 464 VTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTHAEAMSDAKVKN--RGNPNAMTK 521
T+GAR + ++ T A + A+P+ T + M A+ K +G A K
Sbjct: 44 ATTGARPKTETKSVPAARPKTEAQAMSGARPK----TEVQVMGGARPKTEAQGITGARPK 99
Query: 522 AGAKA--NLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLS----CTQPQLVASVQAD 575
A+A R+ + +A+P AR K A+ GT+ +S +Q VA A
Sbjct: 100 TDARAVGGARSKTDAKAIPGARPKDEA--QAWAQSEFGTEAVSQAEGVSQTNAVAWPLAT 157
Query: 576 TLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGK 619
S K +G +M +E VD E P T+G+
Sbjct: 158 AESGSVTKSKG--LSMDRELVNVD----------AETFPGTQGQ 189
>gi|19923967 G protein-coupled receptor associated sorting protein 2
[Homo sapiens]
Length = 838
Score = 218 bits (555), Expect = 6e-56
Identities = 222/840 (26%), Positives = 359/840 (42%), Gaps = 117/840 (13%)
Query: 1608 SQTNGGSWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCS--K 1665
+Q G+ + V +RP Q+ +G+ QV G GA +A G + +
Sbjct: 42 TQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMG----GARPKTEAQGITGAR 97
Query: 1666 PGFEDQAIGGGFWPGAGDQTGG----GSRPGSEDQSSGIGSWGV-------------AGG 1708
P + +A+GG A +T G+RP E Q+ +G A
Sbjct: 98 PKTDARAVGG-----ARSKTDAKAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVA 152
Query: 1709 QVLGGARPGPADQSSGGS------------WAGTGNQSSGRSWIGPGDQ----AVDCSKP 1752
L A G +S G S + GT Q + W GPG++ + S+P
Sbjct: 153 WPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRP 212
Query: 1753 EFEDQACG-GGSWAGAGSQASGESWAGS------------------RPGNEAIGGSRMGS 1793
++A G W+ + + W G R ++ SR S
Sbjct: 213 RAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTNPRSRPRS 272
Query: 1794 EDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGA--EAVIGSWCWTEEKADIVSRP 1851
+ +A SW+ SED+AS F SF V N F P EA I S T + S
Sbjct: 273 KQEAYVDSWSGSEDEASNPF--SFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESES 330
Query: 1852 DDK----------DEATTASRSRAGEEAMICSRIEAENKASSG---SWIRSEEVAYMGSC 1898
+D+ +EA + R R E+ ++ A+ S R EE +GS
Sbjct: 331 EDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSW 390
Query: 1899 VGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLG 1958
AE A E GA A + G E GA G+ A + GA E++
Sbjct: 391 FWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGA--------VAREEAKPE 442
Query: 1959 AGEEAGVESWTLARNVGEDELSRESSP-DIEEISLRSLFWAESENSNTFRSKSGKDASFE 2017
+ EEA SW R DE + +P + ++S R AE N+++ R ++ + + E
Sbjct: 443 SEEEAIFGSWFWDR----DEACFDLNPCPVYKVSDRFRDAAEELNASS-RPQTWDEVTVE 497
Query: 2018 SGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSSESRGIYPYMVPGA 2077
G + + + G+ E SE A + S E + P
Sbjct: 498 FKPGLFHGVGFRSTSPFGIP---------EEASEMLEAKPKNLELSPEGEEQESLLQPDQ 548
Query: 2078 GMGSWDGAMIWSETKFAHQSEASFPVEDESRKQTRTGE--KTRPWSCRC-KHEANMDPRD 2134
+F Q + S+ E R+ R E ++ WSC C + E + +
Sbjct: 549 -----------PSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEE 597
Query: 2135 LEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYPSVRQK 2194
E+ + +++ DP +HEI+ A+ + ++ + +R+ G +S+IE+LLN P VR
Sbjct: 598 FEEFLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTS 657
Query: 2195 ALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEYQHMVT 2254
L + +++ N ++T++ QVCE+T+ + ++S QL G+R++RHLT+T +Y ++
Sbjct: 658 FLENMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIA 717
Query: 2255 NYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKETKENI 2314
NY+S FL LLT + TK HVL MLLN S+NP++ K L A A + + +F+ +ET +NI
Sbjct: 718 NYMSGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNI 777
Query: 2315 LNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDPEVKER 2374
+ +F+NI+ K + D FS L F+ + AK+L+A NDPEV ++
Sbjct: 778 QIVIKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQ 837
Score = 66.6 bits (161), Expect = 3e-10
Identities = 128/516 (24%), Positives = 189/516 (36%), Gaps = 133/516 (25%)
Query: 1427 QASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAGTLDQSGGGSKPRFEN 1486
QA+ G+ E +S + T QA G+R Q GGA T Q G++P+
Sbjct: 43 QATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPK--- 99
Query: 1487 QTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGA- 1545
T+ + GA + + G + ++WA S F V QA G S T A
Sbjct: 100 --TDARAVGGARSKTDAKAIPGARPKDEAQAWAQS------EFGTEAVSQAEGVSQTNAV 151
Query: 1546 GHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRL--GLRDQSSGDSWAGTGDQASGWFC 1603
P + V+ + RE V D+ G + Q W G
Sbjct: 152 AWPLATAE----SGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFG---------- 197
Query: 1604 VCPGSQTNGGSWGGASGQDVGGSRPGPTNQSS--AGSWDSPGSQVSGSCWTGAGAVDQAG 1661
PG +TN GSW SRP ++S +G W + + + S WTG ++
Sbjct: 198 --PGEETNMGSW--------CYSRPRAREEASNESGFWSADETSTASSFWTG----EETS 243
Query: 1662 GCSKPGFEDQAIGGGFWPGAGDQTGGGSRP------------GSEDQSSGIGSWGVAGGQ 1709
S P E A QT SRP GSED++S S+ V G
Sbjct: 244 VRSWPREESNTRSR---HRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV-GEN 299
Query: 1710 VLGGARPGPADQSSGGSWAGTGNQSS----------GRSWIGPGDQA------------- 1746
RP ++++ S T + +SW+ PG++A
Sbjct: 300 TNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPN 359
Query: 1747 ----------VDCSK----PEFEDQACGGGSWAGAGSQASGESWAG----SRPGNE--AI 1786
VD + P FE++ GSW A +AS E A S PG E AI
Sbjct: 360 TALKLRAQKDVDSDRVKQEPRFEEEVI-IGSWFWAEKEASLEGGASAICESEPGTEEGAI 418
Query: 1787 GGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEGFWFGPGAEAVIGSWCWTEEKAD 1846
GGS +E++++ G+ AR E + E+ E EA+ GSW W ++A
Sbjct: 419 GGSAYWAEEKSSLGAVAREEAKP----------ESEE--------EAIFGSWFWDRDEAC 460
Query: 1847 IVSRP-----------DDKDEATTASRSRAGEEAMI 1871
P D +E +SR + +E +
Sbjct: 461 FDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTV 496
Score = 59.7 bits (143), Expect = 3e-08
Identities = 118/541 (21%), Positives = 198/541 (36%), Gaps = 102/541 (18%)
Query: 965 LASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNS 1024
+ ++ E A+ + K V++ D +P+V + P K +
Sbjct: 1 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA 60
Query: 1025 NAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQA 1084
++A+A +G +VQV+ + K + +G + A PK +A A VG A+
Sbjct: 61 RPKTEAQAMSGARPKTEVQVMGGAR------PKTEAQGITGARPKTDARA--VGGAR--- 109
Query: 1085 VANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTS 1144
+ + ++ + GAR K + A + GT A +Q + V+ + P A +S S +
Sbjct: 110 -SKTDAKAIPGARPKDEAQAWAQSEFGTEA----VSQAEGVSQTNAVAWPLATAESGSVT 164
Query: 1145 EAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWI 1204
+++ + D +AE P GTQ + QP W G G E + + W
Sbjct: 165 KSKGLSMDRELVNVDAETFP--------GTQGQKGIQP------WFGPGEETNMGS--WC 208
Query: 1205 KFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSVKSW------ 1258
R + + S W+ DE + W+G +ETSV+SW
Sbjct: 209 YSRPRAREEASNESGFWSADETSTASSFWTG---------------EETSVRSWPREESN 253
Query: 1259 --AGARAENVVGIGTWARAGEQASGGLWAGGQTSEGT----WAGDKASGGAWTGAENQAS 1312
+ RA++ + R+ ++A W+G + W G+ + +A+
Sbjct: 254 TRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTNNLFRPRVREEAN 313
Query: 1313 GGSWALAGNQAIGELWAAGQASDGSW--PGGQASG------------------------- 1345
S + E + + SW PG +A+
Sbjct: 314 IRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRAQKDVDSD 373
Query: 1346 ----VSWVGEEAIGGSWTGAENQAS-EGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTS 1400
EE I GSW AE +AS EG GA A S G + G WA
Sbjct: 374 RVKQEPRFEEEVIIGSWFWAEKEASLEG---GASAICESEPGTEEGAI--GGSAYWAEEK 428
Query: 1401 DQSGG----GSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGS 1456
G +KP E++A GSW +A P + S R + D A++ + S
Sbjct: 429 SSLGAVAREEAKPESEEEAI-FGSWFWDRDEACFDLNPCPVYKVSDR-FRDAAEELNASS 486
Query: 1457 R 1457
R
Sbjct: 487 R 487
Score = 59.7 bits (143), Expect = 3e-08
Identities = 120/551 (21%), Positives = 206/551 (37%), Gaps = 110/551 (19%)
Query: 1073 GADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGET 1132
GA+ SAQ + + E + G + + PK T A T A+P+ S
Sbjct: 3 GAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATT--GARPKTETKSVPAA 60
Query: 1133 LPGARDKSMSTSEAEATAEDEAYAKPEAEAM------PTSESE--GGSGTQACRKTQPNI 1184
P ++MS + + + A+P+ EA P +++ GG+ ++ K P
Sbjct: 61 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIP-- 118
Query: 1185 HDYYWNGIGVEDWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAG-II 1243
G A+ W + F T +VS A+ ++ + +W A+ ++G +
Sbjct: 119 --------GARPKDEAQAWAQSEFGT------EAVSQAEGVSQTNAVAWPLATAESGSVT 164
Query: 1244 RSWAVACDETSV----KSWAGARAENVVGIGTWARAGEQASGGLWAGGQ--------TSE 1291
+S ++ D V +++ G + + GI W GE+ + G W +
Sbjct: 165 KSKGLSMDRELVNVDAETFPGTQGQK--GIQPWFGPGEETNMGSWCYSRPRAREEASNES 222
Query: 1292 GTWAGDKASGGA--WTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASGVSWV 1349
G W+ D+ S + WTG E SW + A Q + S P +
Sbjct: 223 GFWSADETSTASSFWTGEETSVR--SWPREESNTRSRHRAKHQTNPRSRPRSK------- 273
Query: 1350 GEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSGGGSKP 1409
+EA SW+G+E++AS + S+W G + + +P
Sbjct: 274 -QEAYVDSWSGSEDEAS------------NPFSFWVG--------------ENTNNLFRP 306
Query: 1410 RFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGA- 1468
R ++A+ ED+ +SW ++A+ SR H D+
Sbjct: 307 RVREEANIRSKLRTNREDCFESE---SEDEFYKQSWVLPGEEAN--SRFRHRDKEDPNTA 361
Query: 1469 ----WAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQA---GGGSKV-----GPEDQSSGR 1516
+D +PRFE + GSW A +A GG S + G E+ + G
Sbjct: 362 LKLRAQKDVDSDRVKQEPRFEEEVI-IGSWFWAEKEASLEGGASAICESEPGTEEGAIGG 420
Query: 1517 S--WANSGDQISG----GFLVGIVDQANGGSWTGAGHPA--SVGPKPIFEDQVSGRGSWA 1568
S WA + ++A GSW A + P P++ +VS R +
Sbjct: 421 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVY--KVSDR--FR 476
Query: 1569 DAREQVVGDSR 1579
DA E++ SR
Sbjct: 477 DAAEELNASSR 487
Score = 59.7 bits (143), Expect = 3e-08
Identities = 88/386 (22%), Positives = 141/386 (36%), Gaps = 60/386 (15%)
Query: 1390 QAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTA 1449
Q GG+ T Q G++P+ + +A G GA + ++ G + ++WA +
Sbjct: 79 QVMGGARPKTEAQGITGARPKTDARAVG-----GARSKTDAKAIPGARPKDEAQAWAQSE 133
Query: 1450 DQASGGSRLGHVDQSSGGAW------AGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGG 1503
S+ V Q++ AW +G++ +S G S R E + ++ G GQ G
Sbjct: 134 FGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDR-ELVNVDAETFPGTQGQKGI 192
Query: 1504 GSKVGPEDQSSGRSWANSGDQI------SGGFLVGIVDQANGGSWTGAGHPASVGPKPIF 1557
GP ++++ SW S + GF WTG SV P
Sbjct: 193 QPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTG--EETSVRSWPRE 250
Query: 1558 EDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQASGWFCVCPGSQTNGGSWGG 1617
E R A+ Q SR + ++ DSW+G+ D+AS F G TN +
Sbjct: 251 ESNTRSRHR---AKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENTN-NLFRP 306
Query: 1618 ASGQDVGGSRPGPTNQSSA-----------GSWDSPGSQVSGSC-------------WTG 1653
++ TN+ SW PG + +
Sbjct: 307 RVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNTALKLRA 366
Query: 1654 AGAVDQAGGCSKPGFEDQA-IGGGFWPGAGDQTGGG------SRPGSEDQSSGIGSWGVA 1706
VD +P FE++ IG FW GG S PG+E+ + G ++
Sbjct: 367 QKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAE 426
Query: 1707 GGQVLGG-----ARPGPADQSSGGSW 1727
LG A+P +++ GSW
Sbjct: 427 EKSSLGAVAREEAKPESEEEAIFGSW 452
Score = 55.5 bits (132), Expect = 6e-07
Identities = 107/470 (22%), Positives = 185/470 (39%), Gaps = 62/470 (13%)
Query: 911 GAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQR 970
GA ++ A+P+ A + P +N V P VV + T G+ ++
Sbjct: 3 GAEIEPSAQAKPEKKAGEEVIAGPERENDV---PLVVRPKVRTQATTGARP-----KTET 54
Query: 971 ETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISKA 1030
+++P AR K + + ++ MG A+P+ A P + G + + + A
Sbjct: 55 KSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDA 114
Query: 1031 EA--GAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTV----GSAQPQA 1084
+A GA Q + F E + A+ + N+ A P A A + +V G + +
Sbjct: 115 KAIPGARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRE 174
Query: 1085 VANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTS 1144
+ N +ET G + + P T G+ ++P+ + E+ + D++ ST+
Sbjct: 175 LVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADET-STA 233
Query: 1145 EAEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVEDWIAAERWI 1204
+ T E+ + + P ES S +A +T P V+ W +E
Sbjct: 234 SSFWTGEETS-----VRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEA 288
Query: 1205 KFRFQTMDGDWENSVSWADDENEASIGS---------WSGASDKAGIIRSWAVACDE--- 1252
F G+ N++ EA+I S + S+ +SW + +E
Sbjct: 289 SNPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANS 348
Query: 1253 -----------TSVKSWA-----------GARAENVVGIGTWARAGEQAS--GGLWAGGQ 1288
T++K A R E V IG+W A ++AS GG A +
Sbjct: 349 RFRHRDKEDPNTALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICE 408
Query: 1289 TSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSW 1338
+ GT G A GG+ AE ++S G A+A +A E + +A GSW
Sbjct: 409 SEPGTEEG--AIGGSAYWAEEKSSLG--AVAREEAKPE--SEEEAIFGSW 452
Score = 52.4 bits (124), Expect = 5e-06
Identities = 65/265 (24%), Positives = 108/265 (40%), Gaps = 30/265 (11%)
Query: 1842 EEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVGA 1901
E +V RP + +ATT +R + +++ +R + E +A SG+ ++E G+
Sbjct: 29 ENDVPLVVRPKVRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKT 88
Query: 1902 EAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVWSWDGDATTVESRLGAGE 1961
EA A +A A GA + +A A GA P E+ A W+ T S+
Sbjct: 89 EAQGITGARPKTDARAVGGARSKTDAKAIPGARPKDEAQA--WAQSEFGTEAVSQAEGVS 146
Query: 1962 EAGVESWTLA-RNVGEDELSRESSPDIEEISLRS-------------LFWAESENSNT-- 2005
+ +W LA G S+ S D E +++ + ++ E +N
Sbjct: 147 QTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGS 206
Query: 2006 ---FRSKSGKDASFESG--AGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKA 2060
R ++ ++AS ESG + D TS F + SW S +S +AK
Sbjct: 207 WCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSW----PREESNTRSRHRAKH 262
Query: 2061 KKSSESRGIYPYMVPGAGMGSWDGA 2085
+ + SR P A + SW G+
Sbjct: 263 QTNPRSR---PRSKQEAYVDSWSGS 284
Score = 50.8 bits (120), Expect = 2e-05
Identities = 77/270 (28%), Positives = 120/270 (44%), Gaps = 41/270 (15%)
Query: 127 VRTLARNGSTVKMET----VVGVQSQTLAINEAEIKTKPQVEIGA--ETGARSGPGAEVE 180
VRT A G+ K ET +++ A++ A KT+ QV GA +T A+ GA +
Sbjct: 40 VRTQATTGARPKTETKSVPAARPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPK 99
Query: 181 TKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVAMKEAV 240
T A A+ R+ + AKA+ GA P+ E++ A + TEAV+ E V
Sbjct: 100 TDARAVGGARSKTDAKAIPGARPK--DEAQAWAQSEFGTEAVS------------QAEGV 145
Query: 241 TQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVT 300
+QT+A A + E+ + TK+K ++ RE + AET + + I
Sbjct: 146 SQTNAVAWPLATAESGSVTKSKGLSM------DRE-LVNVDAETFPGTQGQKGIQPWFGP 198
Query: 301 QSET----LAVPREVAKMGATNKTGI--VDETKTRAL----EETV--SVAKTQSEARPGA 348
ET R A+ A+N++G DET T + EET S + +S R
Sbjct: 199 GEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGEETSVRSWPREESNTRSRH 258
Query: 349 TVDARGNPNG--MSREVAGVDMKSCAQSQA 376
+ NP S++ A VD S ++ +A
Sbjct: 259 RAKHQTNPRSRPRSKQEAYVDSWSGSEDEA 288
Score = 48.5 bits (114), Expect = 8e-05
Identities = 54/235 (22%), Positives = 95/235 (40%), Gaps = 15/235 (6%)
Query: 176 GAEVETKATAIAIHRANSQAKAMVGAEPETQSESKVVAGTLVMTEAVTLTEVKAKAREVA 235
GAE+E A A + +A V A PE +++ +V V T+A T K + + V
Sbjct: 3 GAEIEPSAQA----KPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVP 58
Query: 236 MKEAVTQTDAEAGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEIN 295
T+ A +G K E A+ KTEA+ + K + + ++ +
Sbjct: 59 AARPKTEAQAMSGARPKTEVQVMGGAR-----PKTEAQGITGARPKTDARAVGGARSKTD 113
Query: 296 RVMVTQSETLAVPREVAKMGATNKTGIVDETKTRALEETVSVAKTQSEARPGATVDARGN 355
+ A P++ A+ A ++ G ++ + +T +VA + A G+ ++G
Sbjct: 114 AKAIPG----ARPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKG- 168
Query: 356 PNGMSREVAGVDMKSCAQSQAVTKIQGDDMPGTGVEDMGNCKTMSRAESGADTRA 410
M RE+ VD ++ +Q IQ PG C + RA A +
Sbjct: 169 -LSMDRELVNVDAETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNES 222
Score = 38.9 bits (89), Expect = 0.061
Identities = 111/552 (20%), Positives = 192/552 (34%), Gaps = 106/552 (19%)
Query: 791 GAGTDTTGSVQPQIVANSQGEVLPGAKN--------KIRGNPTTVPNSGVGPYTTDSARP 842
GA + + +P+ A + P +N K+R TT + +ARP
Sbjct: 3 GAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAARP 62
Query: 843 QAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCET----LPGAKN 898
+ A + P + +V ++A+ GA +AV + +T +PGA+
Sbjct: 63 KTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARP 122
Query: 899 KVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEVLPGAKNKVKGNPNVVSKAGAREDTVG 958
K A S+ G T +Q + V+ + P A +++G+ + G
Sbjct: 123 KDEAQAWAQSEFG----TEAVSQAEGVSQTNAVAWPLA----------TAESGSVTKSKG 168
Query: 959 STQPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDT-MGSAQPQVVANSQRETLPGAR 1017
+ + L + ET PG +G + G E+T MG S + P AR
Sbjct: 169 LSMDRELVNVDAETFPG----TQGQKGIQPWFGPGEETNMG---------SWCYSRPRAR 215
Query: 1018 NKVKGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTV 1077
+ S G + + +SF ++ R SN + A T
Sbjct: 216 EEASNES----------GFWSADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQTN 265
Query: 1078 GSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLPGAR 1137
++P++ + ++ G+ ++ G T + +P++ R
Sbjct: 266 PRSRPRSKQEAYVDSWSGSEDEASNPF----SFWVGENTNNLFRPRV------REEANIR 315
Query: 1138 DKSMSTSE--AEATAEDEAYAKPEAEAMPTSESEGGSGTQACRKTQPNIHDYYWNGIGVE 1195
K + E E+ +EDE Y ++ +P E+ S + K PN
Sbjct: 316 SKLRTNREDCFESESEDEFY--KQSWVLPGEEA--NSRFRHRDKEDPNTA---------- 361
Query: 1196 DWIAAERWIKFRFQTMDGDWENSVSWADDENEASIGSWSGASDKAGIIRSWAVACDETSV 1255
+K R Q D D + E E IGSW A E S+
Sbjct: 362 --------LKLRAQ-KDVDSDRVKQEPRFEEEVIIGSWFWAE-------------KEASL 399
Query: 1256 KSWAGARAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGS 1315
+ A A E+ G G WA ++S G A ++A +E +A GS
Sbjct: 400 EGGASAICESEPG----TEEGAIGGSAYWAEEKSSLGAVAREEAK----PESEEEAIFGS 451
Query: 1316 WALAGNQAIGEL 1327
W ++A +L
Sbjct: 452 WFWDRDEACFDL 463
Score = 38.5 bits (88), Expect = 0.080
Identities = 85/413 (20%), Positives = 154/413 (37%), Gaps = 49/413 (11%)
Query: 397 KTMSRAESGADTRASAQPQIFAKTQTEA--IPGA--KIDAGGNTNAMCKVGAGADVRACI 452
KT ++A SGA + Q A+ +TEA I GA K DA A K A A A
Sbjct: 63 KTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGARP 122
Query: 453 QPQTVAKKQAEVTSGA--RVDGRGNTNVISKAITGADMRAAAQPQAVASTHAEAMSDAKV 510
+ + A Q+E + A + +G TN ++ + A+ + + + ++ DA+
Sbjct: 123 KDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDAET 182
Query: 511 --KNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLSCTQPQL 568
+G G S + P AR+++
Sbjct: 183 FPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFW----------------- 225
Query: 569 VASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKC 628
++ + T S +V + P+E + + + Q+ N R + R K +A
Sbjct: 226 -SADETSTASSFWTGEETSVRSWPREESNTRSRHRAKHQT------NPRSRPRSKQEAYV 278
Query: 629 KTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVCGQPLVVANP 688
+ G + + V L RV R N SK T + +
Sbjct: 279 DSWSGSEDEASNPFSFWVGENTNNLFRPRV--REEANIRSKLRTNREDCFESESEDEFYK 336
Query: 689 QGEALPGA------KNKVKGNPHTVLKVGAGEGTTDSAQPEAVVSFQGEALLGT------ 736
Q LPG +++ K +P+T LK+ A + DS + + F+ E ++G+
Sbjct: 337 QSWVLPGEEANSRFRHRDKEDPNTALKLRA-QKDVDSDRVKQEPRFEEEVIIGSWFWAEK 395
Query: 737 KNKVKGNPNVVLKAEVG--EGAMGTAQLQIMASSKGEALLDSKNKVKGNSNAV 787
+ ++G + + ++E G EGA+G + S A+ + K + A+
Sbjct: 396 EASLEGGASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAI 448
Score = 34.3 bits (77), Expect = 1.5
Identities = 55/224 (24%), Positives = 88/224 (39%), Gaps = 44/224 (19%)
Query: 404 SGADTRASAQPQIFAKTQTEAIPGAKIDAGGNTNAMCKVGAGADVRACIQPQTVAKKQAE 463
+GA+ SAQ + K E I G + + DV ++P K + +
Sbjct: 2 TGAEIEPSAQAKPEKKAGEEVIAGPEREN--------------DVPLVVRP----KVRTQ 43
Query: 464 VTSGARVDGRGNTNVISKAITGADMRAAAQPQAVASTHAEAMSDAKVKN--RGNPNAMTK 521
T+GAR + ++ T A + A+P+ T + M A+ K +G A K
Sbjct: 44 ATTGARPKTETKSVPAARPKTEAQAMSGARPK----TEVQVMGGARPKTEAQGITGARPK 99
Query: 522 AGAKA--NLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLS----CTQPQLVASVQAD 575
A+A R+ + +A+P AR K A+ GT+ +S +Q VA A
Sbjct: 100 TDARAVGGARSKTDAKAIPGARPKDEA--QAWAQSEFGTEAVSQAEGVSQTNAVAWPLAT 157
Query: 576 TLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGK 619
S K +G +M +E VD E P T+G+
Sbjct: 158 AESGSVTKSKG--LSMDRELVNVD----------AETFPGTQGQ 189
>gi|238776793 SVH protein isoform b [Homo sapiens]
Length = 308
Score = 205 bits (521), Expect = 5e-52
Identities = 106/253 (41%), Positives = 169/253 (66%), Gaps = 2/253 (0%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S+++KALNALNN+SV EN K+K Y++QVCED + PLNS VQLAGL L+ ++T+T+++
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ +YI++ ++L G+G TK VL +LLN S+NP+MT+ LL A +S ++++
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 237
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF+NI K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 238 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 295
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 296 EVKEKVVTIIPKI 308
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|31377663 SVH protein isoform a [Homo sapiens]
Length = 343
Score = 205 bits (521), Expect = 5e-52
Identities = 106/253 (41%), Positives = 169/253 (66%), Gaps = 2/253 (0%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 93 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 152
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S+++KALNALNN+SV EN K+K Y++QVCED + PLNS VQLAGL L+ ++T+T+++
Sbjct: 153 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 212
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ +YI++ ++L G+G TK VL +LLN S+NP+MT+ LL A +S ++++
Sbjct: 213 QHMLHSYITDLFQVLLTGNGNTKVQVLKLLLNLSENPAMTEGLLRAQVDSSFLSLYDSHV 272
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF+NI K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 273 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 330
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 331 EVKEKVVTIIPKI 343
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|7662162 ALEX2 protein [Homo sapiens]
Length = 632
Score = 204 bits (518), Expect = 1e-51
Identities = 166/617 (26%), Positives = 276/617 (44%), Gaps = 62/617 (10%)
Query: 1765 AGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEG 1824
A A +A E+ A G EA+ + +E Q+ GS A+ D A
Sbjct: 77 AEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAG-------------- 122
Query: 1825 FWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSG 1884
GP AE+V+G+ A ++ P EA A+ + A A + E + S
Sbjct: 123 --VGPKAESVVGA-----AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRA 175
Query: 1885 SWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVW 1944
+ V EA A E G G A + G TE+
Sbjct: 176 A-------------VPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEA-- 220
Query: 1945 SWDGDATTVESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWAESENSN 2004
T + GA E G V +++++P ++ A +
Sbjct: 221 PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSA----TG 276
Query: 2005 TFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSS 2064
GK + G K K E ++G F G+ A A S+
Sbjct: 277 AVPKGGGKGVTRSRNGGKGKGKKSKVEVD---ELGMGFRPGD--------GAAAAAAASA 325
Query: 2065 ESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESRKQTRTGEKTRPWSCRC 2124
+ VP S +G W++T+ SE R+ ++ P+
Sbjct: 326 NGGQAFLAEVPD----SEEGESGWTDTESDSDSEPETQRRGRGRRPVAMQKRPFPYEI-- 379
Query: 2125 KHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLL 2184
+ + RDL K++ +++ ++DP + ++A L N+A+YS + E +R +GG+ +I +++
Sbjct: 380 --DEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMI 437
Query: 2185 NNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLT 2244
N P +++KAL A+NN+S EN +++ Y+N+V +D + LNS VQ+ GL+ + ++T
Sbjct: 438 NKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMT 497
Query: 2245 ITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINI 2304
IT++YQH++ N I+ F RLL+ G G+ K +L +L NF++NP M K LL P S ++
Sbjct: 498 ITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSL 557
Query: 2305 FSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAA 2364
++ E ++NAL+LFE I + RA+ F +F+K SL++L C KK+RALA
Sbjct: 558 YNSYVESEILINALTLFEII--YDNLRAEVFNYREFNKGSLFYLCTTSGVCVKKIRALAN 615
Query: 2365 ECNDPEVKERVELLISK 2381
+D VK +V L++K
Sbjct: 616 H-HDLLVKVKVIKLVNK 631
Score = 61.2 bits (147), Expect = 1e-08
Identities = 86/337 (25%), Positives = 127/337 (37%), Gaps = 61/337 (18%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLA------------------RNG 134
M R+++ G V AG+VI AG Y +YK+T+GR Q+ + +A R G
Sbjct: 1 MSRVRDAGCVAAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVAGTGARARAGLRAG 60
Query: 135 STVKMETVVGVQSQTLAINEAEIKTKPQVE----IGAETGARSGPGAEVETKATAIAIHR 190
T+ + + G T EAE + + + +GAE A + AE ++
Sbjct: 61 FTIDLGS--GFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQS--------G 110
Query: 191 ANSQAKAMVGAEPETQSESKVVAGTLVMTEAVT----LTEVKAKAREVAMKEAVTQTDAE 246
A SQA+ GA ++ES V A M A+ +TE A AM A +A
Sbjct: 111 AGSQAQEADGAGVGPKAESVVGA---AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEA- 166
Query: 247 AGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVTQSETLA 306
+EA T A V TEA A T+ + A + + + +E
Sbjct: 167 -----PREAETSRAAVPPGTVVPTEA--AAPTEVTEGPGVAAPTKVAEAPGVASPTEAAE 219
Query: 307 VPREVAKMGATNKTGIVDETKTRALEETVSVAKTQS--EARPGATVDA------------ 352
P GA TG + T T V T + +A PGA A
Sbjct: 220 APVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVP 279
Query: 353 RGNPNGMSREVAGVDMKSCAQSQAVTKIQGDDMPGTG 389
+G G++R G K V ++ PG G
Sbjct: 280 KGGGKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDG 316
Score = 33.9 bits (76), Expect = 2.0
Identities = 82/345 (23%), Positives = 125/345 (36%), Gaps = 58/345 (16%)
Query: 597 GVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDS 656
G D + MA+ + A+ T +AR +A G +D+ + P V+ AE D
Sbjct: 30 GRDQTKKRMAKPKNRAVAGTGARARAGLRA----GFTIDLGSGFSPPTPVRAEAE---DR 82
Query: 657 RVDGRGNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGT 716
D +A G +A + A EA GA ++ + GAG G
Sbjct: 83 AQD---EASALDTVGAEA--------VAPAASSAEAQSGAGSQAQEAD------GAGVGP 125
Query: 717 TDSAQPEAVVSFQGEALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDS 776
+ E+VV G A+ G + AE AM A A + E S
Sbjct: 126 ----KAESVV---GAAMASAIAPPPGVTEALGAAEAP--AMAGAPKVAEAPREAET---S 173
Query: 777 KNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYT 836
+ V + ++A A T+ T P + A ++ PG +PT + V
Sbjct: 174 RAAVPPGTVVPTEAAAPTEVTEG--PGVAAPTKVAEAPGV-----ASPTEAAEAPVPATP 226
Query: 837 TDSARPQAVANSQGE-------VLPGAKNKVK----ANLNAVSKAEAGMGATGSVQPQAV 885
T +A P A S G V+PG K A+ A+ KA + GA P+
Sbjct: 227 TGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAV----PKGG 282
Query: 886 ANSHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQG 930
+ G K K + + V + G G A A A++ G
Sbjct: 283 GKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDGAAAAAAASANG 327
Score = 32.7 bits (73), Expect = 4.4
Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 7/158 (4%)
Query: 1019 KVKGNSNAISKAEAGAGIMGSVQVQVVASFQ--GEVLPGAKNKVRGNSNAVPK--AEAGA 1074
K K + A + A A AG+ + + + F V A+++ + ++A+ AEA A
Sbjct: 40 KPKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVA 99
Query: 1075 DTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLP 1134
SA+ Q+ A SQ++ GA K ++ V A A + + ++ +
Sbjct: 100 PAASSAEAQSGAGSQAQEADGAGVGPKAESV-VGAAMASAIAPPPGVTEALGAAEAPAMA 158
Query: 1135 GARDKSMSTSEAEAT--AEDEAYAKPEAEAMPTSESEG 1170
GA + + EAE + A P A PT +EG
Sbjct: 159 GAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEG 196
Score = 31.6 bits (70), Expect = 9.7
Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 33/148 (22%)
Query: 1831 AEAVIGSWCW---------TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKA 1881
A VIG+ W ++ +++P ++ A T +R+RAG
Sbjct: 12 AGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVAGTGARARAG--------------- 56
Query: 1882 SSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGA 1941
+R+ +GS AEA A+ A A GAEA A A + +SGA
Sbjct: 57 -----LRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGA 111
Query: 1942 GVWSWDGDATTV----ESRLGAGEEAGV 1965
G + + D V ES +GA + +
Sbjct: 112 GSQAQEADGAGVGPKAESVVGAAMASAI 139
>gi|29540562 ALEX2 protein [Homo sapiens]
Length = 632
Score = 204 bits (518), Expect = 1e-51
Identities = 166/617 (26%), Positives = 276/617 (44%), Gaps = 62/617 (10%)
Query: 1765 AGAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFEVEANEG 1824
A A +A E+ A G EA+ + +E Q+ GS A+ D A
Sbjct: 77 AEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGAGSQAQEADGAG-------------- 122
Query: 1825 FWFGPGAEAVIGSWCWTEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSG 1884
GP AE+V+G+ A ++ P EA A+ + A A + E + S
Sbjct: 123 --VGPKAESVVGA-----AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEAPREAETSRA 175
Query: 1885 SWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGAGVW 1944
+ V EA A E G G A + G TE+
Sbjct: 176 A-------------VPPGTVVPTEAAAPTEVTEGPGVAAPTKVAEAPGVASPTEAAEA-- 220
Query: 1945 SWDGDATTVESRLGAGEEAGVESWTLARNVGEDELSRESSPDIEEISLRSLFWAESENSN 2004
T + GA E G V +++++P ++ A +
Sbjct: 221 PVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSA----TG 276
Query: 2005 TFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCAGNENTSEDKSAPKAKAKKSS 2064
GK + G K K E ++G F G+ A A S+
Sbjct: 277 AVPKGGGKGVTRSRNGGKGKGKKSKVEVD---ELGMGFRPGD--------GAAAAAAASA 325
Query: 2065 ESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESRKQTRTGEKTRPWSCRC 2124
+ VP S +G W++T+ SE R+ ++ P+
Sbjct: 326 NGGQAFLAEVPD----SEEGESGWTDTESDSDSEPETQRRGRGRRPVAMQKRPFPYEI-- 379
Query: 2125 KHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLL 2184
+ + RDL K++ +++ ++DP + ++A L N+A+YS + E +R +GG+ +I +++
Sbjct: 380 --DEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNANYSCNQETIRKLGGLPIIANMI 437
Query: 2185 NNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLT 2244
N P +++KAL A+NN+S EN +++ Y+N+V +D + LNS VQ+ GL+ + ++T
Sbjct: 438 NKTDPHIKEKALMAMNNLSENYENQGRLQVYMNKVMDDIMASNLNSAVQVVGLKFLTNMT 497
Query: 2245 ITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINI 2304
IT++YQH++ N I+ F RLL+ G G+ K +L +L NF++NP M K LL P S ++
Sbjct: 498 ITNDYQHLLVNSIANFFRLLSQGGGKIKVEILKILSNFAENPDMLKKLLSTQVPASFSSL 557
Query: 2305 FSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAA 2364
++ E ++NAL+LFE I + RA+ F +F+K SL++L C KK+RALA
Sbjct: 558 YNSYVESEILINALTLFEII--YDNLRAEVFNYREFNKGSLFYLCTTSGVCVKKIRALAN 615
Query: 2365 ECNDPEVKERVELLISK 2381
+D VK +V L++K
Sbjct: 616 H-HDLLVKVKVIKLVNK 631
Score = 61.2 bits (147), Expect = 1e-08
Identities = 86/337 (25%), Positives = 127/337 (37%), Gaps = 61/337 (18%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLA------------------RNG 134
M R+++ G V AG+VI AG Y +YK+T+GR Q+ + +A R G
Sbjct: 1 MSRVRDAGCVAAGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVAGTGARARAGLRAG 60
Query: 135 STVKMETVVGVQSQTLAINEAEIKTKPQVE----IGAETGARSGPGAEVETKATAIAIHR 190
T+ + + G T EAE + + + +GAE A + AE ++
Sbjct: 61 FTIDLGS--GFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQS--------G 110
Query: 191 ANSQAKAMVGAEPETQSESKVVAGTLVMTEAVT----LTEVKAKAREVAMKEAVTQTDAE 246
A SQA+ GA ++ES V A M A+ +TE A AM A +A
Sbjct: 111 AGSQAQEADGAGVGPKAESVVGA---AMASAIAPPPGVTEALGAAEAPAMAGAPKVAEA- 166
Query: 247 AGKIVKKEAVTQTKAKAWALVAKTEAKREAMTQTKAETHILAEKETEINRVMVTQSETLA 306
+EA T A V TEA A T+ + A + + + +E
Sbjct: 167 -----PREAETSRAAVPPGTVVPTEA--AAPTEVTEGPGVAAPTKVAEAPGVASPTEAAE 219
Query: 307 VPREVAKMGATNKTGIVDETKTRALEETVSVAKTQS--EARPGATVDA------------ 352
P GA TG + T T V T + +A PGA A
Sbjct: 220 APVPATPTGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAVP 279
Query: 353 RGNPNGMSREVAGVDMKSCAQSQAVTKIQGDDMPGTG 389
+G G++R G K V ++ PG G
Sbjct: 280 KGGGKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDG 316
Score = 33.9 bits (76), Expect = 2.0
Identities = 82/345 (23%), Positives = 125/345 (36%), Gaps = 58/345 (16%)
Query: 597 GVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCTQPQAGVKTPAEALLDS 656
G D + MA+ + A+ T +AR +A G +D+ + P V+ AE D
Sbjct: 30 GRDQTKKRMAKPKNRAVAGTGARARAGLRA----GFTIDLGSGFSPPTPVRAEAE---DR 82
Query: 657 RVDGRGNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGT 716
D +A G +A + A EA GA ++ + GAG G
Sbjct: 83 AQD---EASALDTVGAEA--------VAPAASSAEAQSGAGSQAQEAD------GAGVGP 125
Query: 717 TDSAQPEAVVSFQGEALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDS 776
+ E+VV G A+ G + AE AM A A + E S
Sbjct: 126 ----KAESVV---GAAMASAIAPPPGVTEALGAAEAP--AMAGAPKVAEAPREAET---S 173
Query: 777 KNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYT 836
+ V + ++A A T+ T P + A ++ PG +PT + V
Sbjct: 174 RAAVPPGTVVPTEAAAPTEVTEG--PGVAAPTKVAEAPGV-----ASPTEAAEAPVPATP 226
Query: 837 TDSARPQAVANSQGE-------VLPGAKNKVK----ANLNAVSKAEAGMGATGSVQPQAV 885
T +A P A S G V+PG K A+ A+ KA + GA P+
Sbjct: 227 TGAAAPTGAAESPGTSGSPRTAVVPGTSAAKKATPGAHTGAIPKATSATGAV----PKGG 282
Query: 886 ANSHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQG 930
+ G K K + + V + G G A A A++ G
Sbjct: 283 GKGVTRSRNGGKGKGKKSKVEVDELGMGFRPGDGAAAAAAASANG 327
Score = 32.7 bits (73), Expect = 4.4
Identities = 39/158 (24%), Positives = 67/158 (42%), Gaps = 7/158 (4%)
Query: 1019 KVKGNSNAISKAEAGAGIMGSVQVQVVASFQ--GEVLPGAKNKVRGNSNAVPK--AEAGA 1074
K K + A + A A AG+ + + + F V A+++ + ++A+ AEA A
Sbjct: 40 KPKNRAVAGTGARARAGLRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVA 99
Query: 1075 DTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQIVAGSQGETLP 1134
SA+ Q+ A SQ++ GA K ++ V A A + + ++ +
Sbjct: 100 PAASSAEAQSGAGSQAQEADGAGVGPKAESV-VGAAMASAIAPPPGVTEALGAAEAPAMA 158
Query: 1135 GARDKSMSTSEAEAT--AEDEAYAKPEAEAMPTSESEG 1170
GA + + EAE + A P A PT +EG
Sbjct: 159 GAPKVAEAPREAETSRAAVPPGTVVPTEAAAPTEVTEG 196
Score = 31.6 bits (70), Expect = 9.7
Identities = 37/148 (25%), Positives = 58/148 (39%), Gaps = 33/148 (22%)
Query: 1831 AEAVIGSWCW---------TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKA 1881
A VIG+ W ++ +++P ++ A T +R+RAG
Sbjct: 12 AGIVIGAGAWYCVYKYTRGRDQTKKRMAKPKNRAVAGTGARARAG--------------- 56
Query: 1882 SSGSWIRSEEVAYMGSCVGAEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGTESGA 1941
+R+ +GS AEA A+ A A GAEA A A + +SGA
Sbjct: 57 -----LRAGFTIDLGSGFSPPTPVRAEAEDRAQDEASALDTVGAEAVAPAASSAEAQSGA 111
Query: 1942 GVWSWDGDATTV----ESRLGAGEEAGV 1965
G + + D V ES +GA + +
Sbjct: 112 GSQAQEADGAGVGPKAESVVGAAMASAI 139
>gi|216547715 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|216547682 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|216547672 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|216547663 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|216547655 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|216547646 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|216547639 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|39930463 basic helix-loop-helix domain containing, class B, 9
[Homo sapiens]
Length = 547
Score = 181 bits (459), Expect = 8e-45
Identities = 154/547 (28%), Positives = 259/547 (47%), Gaps = 53/547 (9%)
Query: 1841 TEEKADIVSRPDDKDEATTASRSRAGEEAMICSRIEAENKASSGSWIRSEEVAYMGSCVG 1900
TE+KA I ++ + EAT R A + A+ KA +GS +++ VA M +
Sbjct: 14 TEKKAAIQAKAGAEREATGVVRPVA--------KTRAKAKAKTGS--KTDAVAEMKAVSK 63
Query: 1901 AEAGAGAEAGAGAEAGAGAGAEAGAEAGAGAGAGPGT---ESGAGVWSWDGDATTVESRL 1957
+ A + GA +E A AG + T E+G W W G+ T+ S
Sbjct: 64 NKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTCKNEAGTDAWFWAGEEATINSWF 123
Query: 1958 GAGEEAGVESWT------LARNVGEDELSRESSPDI----------EEISLRSLFWAESE 2001
GEEAG T + V +EL + D EE + + FW E
Sbjct: 124 WNGEEAGNSFSTKNDKPEIGAQVCAEELEPAAGADCKPRSGAEEEEEENVIGNWFW---E 180
Query: 2002 NSNTFRSKSGKDASFESGAGDNTSIKDKFEAAGGVDIGSWFCA--------GNENTSEDK 2053
+T + K S I +K ++ W A G + + +
Sbjct: 181 GDDTSFDPNPKPVSRIVKPQPVYEINEKNRPKDWSEVTIWPNAPAVTPAVLGFRSQAPSE 240
Query: 2054 SAPK-----AKAKKSSESRGIYPYMVPGAGMGSWDGAMIWSETKFAHQSEASFPVEDESR 2108
++P A A++++ S + P S + E +F S+ DE R
Sbjct: 241 ASPPSYIVLASAEENACSLPVATACRPSRNTRSCSQPI--PECRF--DSDPCIQTIDEIR 296
Query: 2109 KQTRTGEKT--RPWSCRCKHEANMDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSY 2166
+Q R E +P++C CK E MD + EKL+ +++ T DP +H+IA A+ + +
Sbjct: 297 RQIRIREVNGIKPFACPCKMECYMDSEEFEKLVSLLKSTTDPLIHKIARIAMGVHNVHPF 356
Query: 2167 SHEVVRNVGGISVIESLLNNPYPSVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTY 2226
+ E + VG +++IESLL+ P P +R+K + LN S E RK++ ++ +C++T+++
Sbjct: 357 AQEFINEVGVVTLIESLLSFPSPEMRKKTVITLNPPS-GDERQRKIELHVKHMCKETMSF 415
Query: 2227 PLNSNVQLAGLRLIRHLTITSEYQHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNP 2286
PLNS Q +GL+++ LT + ++V NY SE LL+ G+ +T++ VL +LLN S+NP
Sbjct: 416 PLNSPGQQSGLKILGQLTTDFVHHYIVANYFSELFHLLSSGNCKTRNLVLKLLLNMSENP 475
Query: 2287 SMTKDLLIANAPTSLINIFSKKETKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLY 2346
+ +D++ A +L IF++KE K N+++ +++F NI H R+ D S N+L
Sbjct: 476 TAARDMINMKALAALKLIFNQKEAKANLVSGVAIFINIKEHI-RKGSIVVVDHLSYNTLM 534
Query: 2347 FLFQRPK 2353
+F+ K
Sbjct: 535 AIFREVK 541
Score = 40.8 bits (94), Expect = 0.016
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 2/99 (2%)
Query: 581 KIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKAKCKTGPGMDMKTCT 640
K K R T K A + KA ++ G P + +A+ KAK KT +MK +
Sbjct: 5 KNKTRAQAKTEKK--AAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVS 62
Query: 641 QPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVC 679
+ + +T AL + + G+ + T KAG ++ C
Sbjct: 63 KNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSSTC 101
Score = 37.7 bits (86), Expect = 0.14
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 765 MASSKGEALLDSKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNP 824
MA +K + +K + K A KAGA + TG V+P ++ + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 825 TTVPNSGVGPYTTDSA--RPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQP 882
V + V T + A P+ + + G+ P A N+ + ++ K EAG A
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGE 115
Query: 883 QAVANS 888
+A NS
Sbjct: 116 EATINS 121
Score = 37.7 bits (86), Expect = 0.14
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 4/97 (4%)
Query: 845 VANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNW 904
+A ++ + AK + KA + A KA A ATG V+P A + + G+K
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQA--KAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEM 58
Query: 905 NAVSKAGAGMDTRGSA--QPQAVANSQGEVLPGAKNK 939
AVSK +T+ A +P+ + + G+ P A N+
Sbjct: 59 KAVSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE 95
Score = 37.0 bits (84), Expect = 0.23
Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 29/147 (19%)
Query: 1053 LPGAKNKVRGNS----NAVPKAEAGA--DTVGSAQPQAVANSQSETLLGARNKVKGNTIA 1106
+ G KNK R + A +A+AGA + G +P A ++++ G++ A
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 1107 VPKAGTGAGTRHSA--QPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164
V K A T+ A +P+ + + G+ P A ++S S+
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNESTSS--------------------- 99
Query: 1165 TSESEGGSGTQACRKTQPNIHDYYWNG 1191
T ++E G+ + I+ ++WNG
Sbjct: 100 TCKNEAGTDAWFWAGEEATINSWFWNG 126
Score = 35.0 bits (79), Expect = 0.88
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 9/117 (7%)
Query: 976 ARNKVKGNSNVVSKAGAREDTMGSAQPQVVANSQRETLPGARNKVKGNSNAISK----AE 1031
A+ K + + + +KAGA + G +P ++ + G++ A+SK AE
Sbjct: 10 AQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKAVSKNKVVAE 69
Query: 1032 AGAGIMGSVQVQVVASFQGEVLPGAKNKVRGNSNAVPKAEAGADTVGSAQPQAVANS 1088
G + + + + G+ P A N+ ++++ K EAG D A +A NS
Sbjct: 70 TKEGALS--EPKTLGKAMGDFTPKAGNE---STSSTCKNEAGTDAWFWAGEEATINS 121
Score = 31.6 bits (70), Expect = 9.7
Identities = 24/109 (22%), Positives = 46/109 (42%), Gaps = 11/109 (10%)
Query: 933 LPGAKNKVKGNPN------VVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNV 986
+ G KNK + + +KAGA + G +P ++ + G++
Sbjct: 1 MAGTKNKTRAQAKTEKKAAIQAKAGAEREATGVVRPVAKTRAKAKAKTGSKTDAVAEMKA 60
Query: 987 VSKAGAREDTMGSA--QPQVVANSQRETLPGARNKVKGNSNAISKAEAG 1033
VSK +T A +P+ + + + P A N+ ++++ K EAG
Sbjct: 61 VSKNKVVAETKEGALSEPKTLGKAMGDFTPKAGNE---STSSTCKNEAG 106
>gi|169165522 PREDICTED: similar to SVH protein isoform 1 [Homo
sapiens]
Length = 284
Score = 172 bits (435), Expect = 5e-42
Identities = 94/253 (37%), Positives = 153/253 (60%), Gaps = 26/253 (10%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S+++KALNALNN+SV EN K+K Y++QVCED + PLNS VQLAGLRL+ ++T+T+++
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ +YI++ ++L G+G TK +S ++++
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK------------------------VDSSFLSLYDSHV 213
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF+NI K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 214 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 271
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 272 EVKEKVVTIIPKI 284
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|238776797 SVH protein isoform e [Homo sapiens]
Length = 284
Score = 169 bits (429), Expect = 2e-41
Identities = 93/253 (36%), Positives = 152/253 (60%), Gaps = 26/253 (10%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S+++KALNALNN+SV EN K+K Y++QVCED + PLNS VQLAGL L+ ++T+T+++
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLTLLTNMTVTNDH 177
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ +YI++ ++L G+G TK +S ++++
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK------------------------VDSSFLSLYDSHV 213
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF+NI K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 214 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 271
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 272 EVKEKVVTIIPKI 284
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|169165931 PREDICTED: similar to SVH protein isoform 1 [Homo
sapiens]
Length = 284
Score = 169 bits (428), Expect = 3e-41
Identities = 93/253 (36%), Positives = 152/253 (60%), Gaps = 26/253 (10%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S++ KALNALNN+SV EN K+K Y++QVCED + PLNS VQLAGLRL+ ++T+T+++
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ +YI++ ++L G+G TK +S ++++
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK------------------------VDSSFLSLYDSHV 213
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF++I K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 214 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 271
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 272 EVKEKVVTIIPKI 284
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|113414573 PREDICTED: similar to SVH protein isoform 2 [Homo
sapiens]
Length = 284
Score = 169 bits (428), Expect = 3e-41
Identities = 93/253 (36%), Positives = 152/253 (60%), Gaps = 26/253 (10%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S++ KALNALNN+SV EN K+K Y++QVCED + PLNS VQLAGLRL+ ++T+T+++
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAVQLAGLRLLTNMTVTNDH 177
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
QHM+ +YI++ ++L G+G TK +S ++++
Sbjct: 178 QHMLHSYITDLFQVLLTGNGNTK------------------------VDSSFLSLYDSHV 213
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF++I K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 214 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 271
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 272 EVKEKVVTIIPKI 284
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|169165524 PREDICTED: similar to SVH protein isoform 2 [Homo
sapiens]
Length = 253
Score = 122 bits (305), Expect = 5e-27
Identities = 80/253 (31%), Positives = 126/253 (49%), Gaps = 57/253 (22%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S+++KALNALNN+SV EN K+K Y++QVCED + PLNS V
Sbjct: 118 SIKEKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAV----------------- 160
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
L G+G TK +S ++++
Sbjct: 161 --------------LLTGNGNTK------------------------VDSSFLSLYDSHV 182
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF+NI K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 183 AKEILLRVLTLFQNIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 240
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 241 EVKEKVVTIIPKI 253
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|113415138 PREDICTED: similar to SVH protein isoform 2 [Homo
sapiens]
Length = 253
Score = 119 bits (298), Expect = 4e-26
Identities = 79/253 (31%), Positives = 125/253 (49%), Gaps = 57/253 (22%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S++ KALNALNN+SV EN K+K Y++QVCED + PLNS V
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAV----------------- 160
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
L G+G TK +S ++++
Sbjct: 161 --------------LLTGNGNTK------------------------VDSSFLSLYDSHV 182
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF++I K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 183 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 240
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 241 EVKEKVVTIIPKI 253
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
>gi|169165133 PREDICTED: similar to SVH protein isoform 1 [Homo
sapiens]
Length = 253
Score = 119 bits (298), Expect = 4e-26
Identities = 79/253 (31%), Positives = 125/253 (49%), Gaps = 57/253 (22%)
Query: 2130 MDPRDLEKLICMIEMTEDPSVHEIANNALYNSADYSYSHEVVRNVGGISVIESLLNNPYP 2189
++ L+KL+ ++E TEDP + E A L N+A +S + ++R +GGI ++ + +N+
Sbjct: 58 LNAEQLQKLLYLLESTEDPVIIERALITLGNNAAFSVNQAIIRELGGIPIVANKINHSNQ 117
Query: 2190 SVRQKALNALNNISVAAENHRKVKTYLNQVCEDTVTYPLNSNVQLAGLRLIRHLTITSEY 2249
S++ KALNALNN+SV EN K+K Y++QVCED + PLNS V
Sbjct: 118 SIKDKALNALNNLSVNVENQIKIKIYISQVCEDVFSGPLNSAV----------------- 160
Query: 2250 QHMVTNYISEFLRLLTVGSGETKDHVLGMLLNFSKNPSMTKDLLIANAPTSLINIFSKKE 2309
L G+G TK +S ++++
Sbjct: 161 --------------LLTGNGNTK------------------------VDSSFLSLYDSHV 182
Query: 2310 TKENILNALSLFENINYHFKRRAKAFTQDKFSKNSLYFLFQRPKACAKKLRALAAECNDP 2369
KE +L L+LF++I K Q F++ SL+FL + CA+K+RAL + +D
Sbjct: 183 AKEILLRVLTLFQHIKNCLKIEGHLAVQPTFTEGSLFFLL-HGEECAQKIRAL-VDHHDA 240
Query: 2370 EVKERVELLISKL 2382
EVKE+V +I K+
Sbjct: 241 EVKEKVVTIIPKI 253
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/43 (46%), Positives = 26/43 (60%)
Query: 93 MGRIQEVGWVTAGLVIWAGTCYYIYKFTKGRAQSVRTLARNGS 135
MG + GWV AGL++ AG CY IY+ T+GR + R L S
Sbjct: 1 MGGPRGAGWVAAGLLLGAGACYCIYRLTRGRRRGDRELGIRSS 43
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,171,301
Number of Sequences: 37866
Number of extensions: 4961922
Number of successful extensions: 36421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 220
Number of HSP's successfully gapped in prelim test: 518
Number of HSP's that attempted gapping in prelim test: 20494
Number of HSP's gapped (non-prelim): 8913
length of query: 2382
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2263
effective length of database: 13,741,464
effective search space: 31096933032
effective search space used: 31096933032
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.