Search of human proteins with 119829183

Search of human proteins with 119829183

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119829183 cytochrome P450, family 11, subfamily B,
polypeptide 2 precursor [Homo sapiens]
         (503 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119829183 cytochrome P450, family 11, subfamily B, polypeptid...  1016   0.0  
gi|61743918 cytochrome P450, family 11, subfamily B, polypeptide...   943   0.0  
gi|71067343 cytochrome P450, family 11, subfamily B, polypeptide...   753   0.0  
gi|153218646 cytochrome P450, family 11, subfamily A, polypeptid...   344   9e-95
gi|153218654 cytochrome P450, family 11, subfamily A, polypeptid...   254   1e-67
gi|4503213 cytochrome P450, family 27, subfamily B, polypeptide ...   210   3e-54
gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1 ...   206   5e-53
gi|4503211 cytochrome P450, family 27, subfamily A, polypeptide ...   187   3e-47
gi|167466231 cytochrome P450, family 27, subfamily C, polypeptid...   175   8e-44
gi|193083117 cytochrome P450 family 24 subfamily A polypeptide 1...   149   4e-36
gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide...   104   2e-22
gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5...   100   2e-21
gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide ...   100   4e-21
gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide ...    98   2e-20
gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide ...    96   1e-19
gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide...    91   2e-18
gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7...    89   9e-18
gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8...    87   4e-17
gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide ...    87   5e-17
gi|190570174 cytochrome P450, family 21, subfamily A, polypeptid...    84   2e-16
gi|14550409 cytochrome P450, family 21, subfamily A, polypeptide...    84   2e-16
gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [H...    82   1e-15
gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [H...    82   1e-15
gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide ...    81   3e-15
gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide ...    80   4e-15
gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide ...    80   4e-15
gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11...    80   6e-15
gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11...    80   6e-15
gi|18491008 cytochrome P450, family 2, subfamily J, polypeptide ...    79   1e-14
gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide...    79   1e-14

>gi|119829183 cytochrome P450, family 11, subfamily B, polypeptide 2
           precursor [Homo sapiens]
          Length = 503

 Score = 1016 bits (2626), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 1   MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQG 60
           MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQG
Sbjct: 1   MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQG 60

Query: 61  YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYR 120
           YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYR
Sbjct: 61  YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYR 120

Query: 121 QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA 180
           QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA
Sbjct: 121 QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA 180

Query: 181 RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM 240
           RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
Sbjct: 181 RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM 240

Query: 241 PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS 300
           PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS
Sbjct: 241 PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS 300

Query: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 360
           LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT
Sbjct: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 360

Query: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRP 420
           ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRP
Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRP 420

Query: 421 ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQED 480
           ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQED
Sbjct: 421 ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQED 480

Query: 481 IKMVYSFILRPGTSPLLTFRAIN 503
           IKMVYSFILRPGTSPLLTFRAIN
Sbjct: 481 IKMVYSFILRPGTSPLLTFRAIN 503


>gi|61743918 cytochrome P450, family 11, subfamily B, polypeptide 1
           isoform 1 precursor [Homo sapiens]
          Length = 503

 Score =  943 bits (2437), Expect = 0.0
 Identities = 469/503 (93%), Positives = 480/503 (95%)

Query: 1   MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQG 60
           MALRAKAEVC+A PWLSLQRA+ALGTRAAR PRTVLPFEAMP+ PGNRWLRLLQIWREQG
Sbjct: 1   MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQG 60

Query: 61  YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYR 120
           YE LHLE+HQTFQELGPIFRY+LGG  MVCVMLPEDVEKLQQVDSLHP RM LEPWVAYR
Sbjct: 61  YEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR 120

Query: 121 QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA 180
           QHRGHKCGVFLLNGPEWRFNRLRLNP+VLSP AVQRFLPMVDAVARDFSQALKKKVLQNA
Sbjct: 121 QHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNA 180

Query: 181 RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM 240
           RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
Sbjct: 181 RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM 240

Query: 241 PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS 300
           PRSLSRW SPKVWKEHFEAWDCIFQYGDNCIQKIYQELAF+RPQ YT IVAELLL AELS
Sbjct: 241 PRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300

Query: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 360
            +AIKANSMELTAGSVDTT FPLLMTLFELARNP+VQQ LRQESLAAAASISEHPQKATT
Sbjct: 301 PDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATT 360

Query: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRP 420
           ELPLLRAALKETLRLYPVGLFLERV SSDLVLQNYHIPAGTLV+VFLYSLGRN ALFPRP
Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRP 420

Query: 421 ERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQED 480
           ERYNPQRWLDIRGSGRNF+HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKH  VETLTQED
Sbjct: 421 ERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQED 480

Query: 481 IKMVYSFILRPGTSPLLTFRAIN 503
           IKMVYSFILRP   PLLTFRAIN
Sbjct: 481 IKMVYSFILRPSMFPLLTFRAIN 503


>gi|71067343 cytochrome P450, family 11, subfamily B, polypeptide 1
           isoform 2 precursor [Homo sapiens]
          Length = 437

 Score =  753 bits (1943), Expect = 0.0
 Identities = 375/402 (93%), Positives = 384/402 (95%)

Query: 1   MALRAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQG 60
           MALRAKAEVC+A PWLSLQRA+ALGTRAAR PRTVLPFEAMP+ PGNRWLRLLQIWREQG
Sbjct: 1   MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQG 60

Query: 61  YEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYR 120
           YE LHLE+HQTFQELGPIFRY+LGG  MVCVMLPEDVEKLQQVDSLHP RM LEPWVAYR
Sbjct: 61  YEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR 120

Query: 121 QHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNA 180
           QHRGHKCGVFLLNGPEWRFNRLRLNP+VLSP AVQRFLPMVDAVARDFSQALKKKVLQNA
Sbjct: 121 QHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNA 180

Query: 181 RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM 240
           RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM
Sbjct: 181 RGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFM 240

Query: 241 PRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAELS 300
           PRSLSRW SPKVWKEHFEAWDCIFQYGDNCIQKIYQELAF+RPQ YT IVAELLL AELS
Sbjct: 241 PRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300

Query: 301 LEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATT 360
            +AIKANSMELTAGSVDTT FPLLMTLFELARNP+VQQ LRQESLAAAASISEHPQKATT
Sbjct: 301 PDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATT 360

Query: 361 ELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTL 402
           ELPLLRAALKETLRLYPVGLFLERV SSDLVLQNYHIPAG L
Sbjct: 361 ELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGVL 402



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 36/54 (66%), Positives = 42/54 (77%), Gaps = 4/54 (7%)

Query: 454 RLAEAEMLLLLHH----VLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN 503
           R+A ++++L  +H    VLKH  VETLTQEDIKMVYSFILRP   PLLTFRAIN
Sbjct: 384 RVASSDLVLQNYHIPAGVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAIN 437


>gi|153218646 cytochrome P450, family 11, subfamily A, polypeptide 1
           isoform a precursor [Homo sapiens]
          Length = 521

 Score =  344 bits (883), Expect = 9e-95
 Identities = 193/496 (38%), Positives = 281/496 (56%), Gaps = 3/496 (0%)

Query: 11  VAAPWLSLQRARA-LGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQGYEHLHLEMH 69
           ++AP   L R R   G  A  + R+  PF  +P    N WL L   WRE G   +HL   
Sbjct: 20  LSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHV 79

Query: 70  QTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCGV 129
           Q FQ+ GPI+R  LG    V V+ PEDV  L + +  +P R ++ PWVAY Q+     GV
Sbjct: 80  QNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGV 139

Query: 130 FLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQ 189
            L     W+ +R+ LN +V++P+A + FLP++DAV+RDF   L +++ +   G+ + D+ 
Sbjct: 140 LLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDIS 199

Query: 190 PSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWIS 249
             +F +  E+    +FGER G++    +  +  F+ A+  MF ++V ++ +P  L R   
Sbjct: 200 DDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFR 259

Query: 250 PKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQH--YTGIVAELLLKAELSLEAIKAN 307
            K WK+H  AWD IF   D   Q  Y EL      H  Y GI+  LL  +++S E IKAN
Sbjct: 260 TKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKAN 319

Query: 308 SMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRA 367
             E+ AG VDTT+  L   L+E+ARN  VQ +LR E LAA              +PLL+A
Sbjct: 320 VTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKA 379

Query: 368 ALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQR 427
           ++KETLRL+P+ + L+R + +DLVL++Y IPA TLVQV +Y+LGR    F  PE ++P R
Sbjct: 380 SIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTR 439

Query: 428 WLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSF 487
           WL    +   F ++ FG+G+RQCLGRR+AE EM + L ++L++F VE     D+   ++ 
Sbjct: 440 WLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNL 499

Query: 488 ILRPGTSPLLTFRAIN 503
           IL P      TF   N
Sbjct: 500 ILMPEKPISFTFWPFN 515


>gi|153218654 cytochrome P450, family 11, subfamily A, polypeptide 1
           isoform b [Homo sapiens]
          Length = 363

 Score =  254 bits (650), Expect = 1e-67
 Identities = 140/357 (39%), Positives = 209/357 (58%), Gaps = 2/357 (0%)

Query: 149 LSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGER 208
           ++P+A + FLP++DAV+RDF   L +++ +   G+ + D+   +F +  E+    +FGER
Sbjct: 1   MAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGER 60

Query: 209 LGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGD 268
            G++    +  +  F+ A+  MF ++V ++ +P  L R    K WK+H  AWD IF   D
Sbjct: 61  QGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKAD 120

Query: 269 NCIQKIYQELAFNRPQH--YTGIVAELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMT 326
              Q  Y EL      H  Y GI+  LL  +++S E IKAN  E+ AG VDTT+  L   
Sbjct: 121 IYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWH 180

Query: 327 LFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVV 386
           L+E+ARN  VQ +LR E LAA              +PLL+A++KETLRL+P+ + L+R +
Sbjct: 181 LYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYL 240

Query: 387 SSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFG 446
            +DLVL++Y IPA TLVQV +Y+LGR    F  PE ++P RWL    +   F ++ FG+G
Sbjct: 241 VNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWG 300

Query: 447 MRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKMVYSFILRPGTSPLLTFRAIN 503
           +RQCLGRR+AE EM + L ++L++F VE     D+   ++ IL P      TF   N
Sbjct: 301 VRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFN 357


>gi|4503213 cytochrome P450, family 27, subfamily B, polypeptide 1
           [Homo sapiens]
          Length = 508

 Score =  210 bits (534), Expect = 3e-54
 Identities = 145/435 (33%), Positives = 212/435 (48%), Gaps = 16/435 (3%)

Query: 52  LLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRM 111
           L +++ + G   LH    Q     GP++  + G  R V V  P  VE+L + +   P R 
Sbjct: 49  LAELFCKGGLSRLHELQVQGAAHFGPVWLASFGTVRTVYVAAPALVEELLRQEGPRPERC 108

Query: 112 ILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQA 171
              PW  +R+ R   CG+    G EW+  R  L P +L P+A  R+   ++ V  D  + 
Sbjct: 109 SFSPWTEHRRCRQRACGLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRR 168

Query: 172 LKKKVLQNARGS----LTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHAL 227
           L++   Q  RG+    L  DV    + + +E     L G RLG +       +  F+ A+
Sbjct: 169 LRR---QRGRGTGPPALVRDVAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPDTETFIRAV 225

Query: 228 EVMFKSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFN---RPQ 284
             +F ST+  M MP  L R + P  W      WD +F +    +++   E A     +P+
Sbjct: 226 GSVFVSTLLTMAMPHWL-RHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPE 284

Query: 285 HYTGIVAEL---LLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILR 341
                 A L   L + EL  ++I  N  EL    VDT +  L   L+EL+R+P+VQ  L 
Sbjct: 285 KDLESGAHLTHFLFREELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALH 344

Query: 342 QESLAAAASISEHPQKAT--TELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPA 399
            E  AA +  S     AT  ++LPLL+A +KE LRLYPV     RV   D+ + +Y IP 
Sbjct: 345 SEITAALSPGSSAYPSATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPK 404

Query: 400 GTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAE 459
            TLV +  Y+  R+ A FP P  + P RWL    +   F  +PFGFG R C+GRRLAE E
Sbjct: 405 NTLVTLCHYATSRDPAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464

Query: 460 MLLLLHHVLKHFLVE 474
           + + L  +L HF V+
Sbjct: 465 LQMALAQILTHFEVQ 479


>gi|55770850 cytochrome P450 family 24 subfamily A polypeptide 1
           isoform 1 precursor [Homo sapiens]
          Length = 514

 Score =  206 bits (523), Expect = 5e-53
 Identities = 130/448 (29%), Positives = 227/448 (50%), Gaps = 6/448 (1%)

Query: 52  LLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRM 111
           LLQI  + G +  H  + +  ++ G IFR  LG    V +  P  +E L + +S +P R+
Sbjct: 70  LLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEALYRTESAYPQRL 129

Query: 112 ILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQA 171
            ++PW AYR +R    G+ +L G +W+  R      ++ P  V +    ++ V  DF   
Sbjct: 130 EIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKLDNKINEVLADFMGR 189

Query: 172 LKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMF 231
           + +  L + RG +  D+   +  ++ E+  L L+ +R GL+  +    ++NF+ A++ M 
Sbjct: 190 IDE--LCDERGHVE-DLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIMAIKTMM 246

Query: 232 KSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVA 291
            +  ++M  P  L + ++ KVW++H  AWD IF+    CI    ++ +    Q     + 
Sbjct: 247 STFGRMMVTPVELHKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYS---QQPSADFLC 303

Query: 292 ELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASI 351
           ++  +  LS + + A   EL   +V+TTA  L+  L+ L+RNP VQQ L +E  +     
Sbjct: 304 DIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPEN 363

Query: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLG 411
                +    +P L+A LKE++RL P   F  R +    VL  Y +P GT++ +    LG
Sbjct: 364 QVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLG 423

Query: 412 RNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471
            +   F    ++ P+RWL  +     F H+PFG G R C+GRRLAE ++ L L  +++ +
Sbjct: 424 SSEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKY 483

Query: 472 LVETLTQEDIKMVYSFILRPGTSPLLTF 499
            ++    E ++M++S  L P     + F
Sbjct: 484 DIQATDNEPVEMLHSGTLVPSRELPIAF 511


>gi|4503211 cytochrome P450, family 27, subfamily A, polypeptide 1
           precursor [Homo sapiens]
          Length = 531

 Score =  187 bits (474), Expect = 3e-47
 Identities = 143/516 (27%), Positives = 237/516 (45%), Gaps = 35/516 (6%)

Query: 4   RAKAEVCVAAPWLSLQRARALGTRAARAPRTVLPFEAMPQHPGNRWLRLLQIWREQGYEH 63
           RAKA +  A P      A   G    R  R++   E +P+    R+   L +   QGY  
Sbjct: 26  RAKAAIPAALPSDKATGAPGAGPGVRRRQRSL---EEIPRLGQLRFFFQLFV---QGYA- 78

Query: 64  LHLEMHQTF----QELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRMILEPWVAY 119
             L++HQ       + GP++   LG    V +     +E++ + +  +P R  +E W  +
Sbjct: 79  --LQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEH 136

Query: 120 RQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQN 179
           R       G F   G  W   R  LN  +L P     +    + V  DF   L +   ++
Sbjct: 137 RDQHDLTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAES 196

Query: 180 ARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMF 239
           A G+   D+    +++ +EA    LF +R+G +  S    ++ F+ ++ +MF++++   F
Sbjct: 197 ASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATF 256

Query: 240 MPRSLSRWISPKV--WKEHFEAWDCIFQYG----DNCIQKIYQELAFNRPQ--HYTGIVA 291
           +P+    W  P +  WK + + W+ IF +G    D  ++ +  +L    P     +G + 
Sbjct: 257 LPK----WTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLH 312

Query: 292 ELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASI 351
            LL   +LS      +  EL    VDTT+  L   L+ L+++P++Q+ L +E +    + 
Sbjct: 313 FLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAG 372

Query: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLG 411
                K    +PLL+A LKETLRLYPV     R++  ++ +  +  P  T      Y + 
Sbjct: 373 QVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVS 432

Query: 412 RNAALFPRPERYNPQRWLDIRGS-------GRNFHHVPFGFGMRQCLGRRLAEAEMLLLL 464
           R+   F  PE + P RWL  R S          F  VPFG+G+R CLGRR+AE EM LLL
Sbjct: 433 RDPTAFSEPESFQPHRWL--RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLL 490

Query: 465 HHVLKHFLVETLTQE-DIKMVYSFILRPGTSPLLTF 499
             +++ + V    +  ++K V   +L P     L F
Sbjct: 491 ARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQF 526


>gi|167466231 cytochrome P450, family 27, subfamily C, polypeptide 1
           [Homo sapiens]
          Length = 372

 Score =  175 bits (444), Expect = 8e-44
 Identities = 116/344 (33%), Positives = 183/344 (53%), Gaps = 11/344 (3%)

Query: 144 LNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLA 203
           L   +L PK V  +   V+ V  D  + +     Q   G    +V    F Y++E     
Sbjct: 5   LRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGVATI 64

Query: 204 LFGERLGLVGHSPSSASLNFLHALEVMF---KSTVQLMFMPRSLSRWISPKVWKEHFEAW 260
           L+  RLG + +S    ++ ++ ALE+MF   K+++    +PR L  +I PK W+E   +W
Sbjct: 65  LYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFI-PKPWREFCRSW 123

Query: 261 DCIFQYG----DNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSV 316
           D +F++     DN ++ I  ++   R +   G++  L L   L+L+ I AN  E+    V
Sbjct: 124 DGLFKFSQIHVDNKLRDIQYQMDRGR-RVSGGLLTYLFLSQALTLQEIYANVTEMLLAGV 182

Query: 317 DTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAALKETLRLY 376
           DTT+F L  T++ LAR+P+VQQ + +E +               ++PL+RA LKETLRL+
Sbjct: 183 DTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKETLRLF 242

Query: 377 PVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRWLDIRGSGR 436
           PV     RV   DLV+  Y IP GT + +  Y+       FPR + + P+RWL      R
Sbjct: 243 PVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRPERWLRKGDLDR 302

Query: 437 --NFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQ 478
             NF  +PFG G+R C+GRR+AE E+ L++  +L+HF ++T +Q
Sbjct: 303 VDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQ 346


>gi|193083117 cytochrome P450 family 24 subfamily A polypeptide 1
           isoform 2 precursor [Homo sapiens]
          Length = 448

 Score =  149 bits (377), Expect = 4e-36
 Identities = 100/349 (28%), Positives = 174/349 (49%), Gaps = 6/349 (1%)

Query: 52  LLQIWREQGYEHLHLEMHQTFQELGPIFRYNLGGPRMVCVMLPEDVEKLQQVDSLHPCRM 111
           LLQI  + G +  H  + +  ++ G IFR  LG    V +  P  +E L + +S +P R+
Sbjct: 70  LLQILWKGGLKKQHDTLVEYHKKYGKIFRMKLGSFESVHLGSPCLLEALYRTESAYPQRL 129

Query: 112 ILEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQA 171
            ++PW AYR +R    G+ +L G +W+  R      ++ P  V +    ++ V  DF   
Sbjct: 130 EIKPWKAYRDYRKEGYGLLILEGEDWQRVRSAFQKKLMKPGEVMKLDNKINEVLADFMGR 189

Query: 172 LKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMF 231
           + +  L + RG +  D+   +  ++ E+  L L+ +R GL+  +    ++NF+ A++ M 
Sbjct: 190 IDE--LCDERGHVE-DLYSELNKWSFESICLVLYEKRFGLLQKNAGDEAVNFIMAIKTMM 246

Query: 232 KSTVQLMFMPRSLSRWISPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVA 291
            +  ++M  P  L + ++ KVW++H  AWD IF+    CI    ++ +    Q     + 
Sbjct: 247 STFGRMMVTPVELHKSLNTKVWQDHTLAWDTIFKSVKACIDNRLEKYS---QQPSADFLC 303

Query: 292 ELLLKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASI 351
           ++  +  LS + + A   EL   +V+TTA  L+  L+ L+RNP VQQ L +E  +     
Sbjct: 304 DIYHQNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPEN 363

Query: 352 SEHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAG 400
                +    +P L+A LKE++RL P   F  R +    VL  Y +P G
Sbjct: 364 QVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKG 412


>gi|187960086 cytochrome P450, family 4, subfamily v, polypeptide 2
           [Homo sapiens]
          Length = 525

 Score =  104 bits (260), Expect = 2e-22
 Identities = 113/445 (25%), Positives = 192/445 (43%), Gaps = 53/445 (11%)

Query: 77  PIFRYNLGGPRMVCVMLPEDVEKL----QQVDSLHPCRMILEPWVAYRQHRGHKCGVFLL 132
           P+ +  +G   MV +   E+VE +    +Q+D     +  LEPW+          G+   
Sbjct: 88  PLLKLWVGPVPMVALYNAENVEVILTSSKQIDKSSMYKF-LEPWLGL--------GLLTS 138

Query: 133 NGPEWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSI 192
            G +WR  R  L P       ++ FL +++  A    + L+K + Q A            
Sbjct: 139 TGNKWRSRRKMLTP-TFHFTILEDFLDIMNEQANILVKKLEKHINQEAFNCF-------- 189

Query: 193 FHYTIEASNL---ALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWIS 249
           F+ T+ A ++      G+ +G   +  S          E++F+  +++ ++   L   + 
Sbjct: 190 FYITLCALDIICETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRR-IKMPWLWLDLWYLMF 248

Query: 250 PKVWKEHFEAWDCIFQYGDNCIQKIYQELAFNRPQHYTG-----------IVAELLLKA- 297
            + W EH ++   +  + ++ I +   E+  N      G              +LLL   
Sbjct: 249 KEGW-EHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVT 307

Query: 298 -----ELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASIS 352
                 LS E I+           DTTA  +  +L+ L  NP+VQ+ +  E L      S
Sbjct: 308 DDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHE-LDDVFGKS 366

Query: 353 EHPQKATTE----LPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLY 408
           + P  AT E    L  L   +KETLRL+P      R VS D  +  Y +  GT   +  Y
Sbjct: 367 DRP--ATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPY 424

Query: 409 SLGRNAALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHV 467
           +L R+   FP PE + P+R+      GR+ + +VPF  G R C+G++ A  E   +L  +
Sbjct: 425 ALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCI 484

Query: 468 LKHFLVET-LTQEDIKMVYSFILRP 491
           L+HF +E+   +E++ +    ILRP
Sbjct: 485 LRHFWIESNQKREELGLEGQLILRP 509


>gi|4503231 cytochrome P450, family 3, subfamily A, polypeptide 5
           [Homo sapiens]
          Length = 502

 Score =  100 bits (250), Expect = 2e-21
 Identities = 66/198 (33%), Positives = 103/198 (52%), Gaps = 3/198 (1%)

Query: 296 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 355
           KA   LE + A S+       +TT+  L  TL+ELA +PDVQQ L++E  A   + +   
Sbjct: 288 KALSDLE-LAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPT 346

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAA 415
             A  ++  L   + ETLRL+PV + LER    D+ +    IP G++V +  Y+L  +  
Sbjct: 347 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPK 406

Query: 416 LFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVET 475
            +  PE + P+R+   + S   + + PFG G R C+G R A   M L L  VL++F  + 
Sbjct: 407 YWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466

Query: 476 L--TQEDIKMVYSFILRP 491
              TQ  +K+    +L+P
Sbjct: 467 CKETQIPLKLDTQGLLQP 484


>gi|16933533 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 2 [Homo sapiens]
          Length = 503

 Score =  100 bits (248), Expect = 4e-21
 Identities = 96/375 (25%), Positives = 171/375 (45%), Gaps = 33/375 (8%)

Query: 136 EWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHY 195
           EW+  R  L+P   S K    F  MV  +++     L + + Q A  S +++++     Y
Sbjct: 125 EWKRIRTLLSPAFTSVK----FKEMVPIISQ-CGDMLVRSLRQEAENSKSINLKDFFGAY 179

Query: 196 TIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKE 255
           T++     LFG  L  + +       N    L++ F     L+    SL  +++P     
Sbjct: 180 TMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLI---SLFPFLTPV---- 232

Query: 256 HFEAWDC------IFQYGDNCIQKIYQELAFNRPQHYTGIVAELL----------LKAEL 299
            FEA +       +  +  N I+++ +    ++ +H      +++           KA  
Sbjct: 233 -FEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALS 291

Query: 300 SLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKAT 359
            LE + A S+ +   + DTT+  L   ++ELA +PDVQQ L++E  A   + +     A 
Sbjct: 292 DLELV-AQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL 350

Query: 360 TELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPR 419
            ++  L   + ETLRL+PV   + RV   D+ +    IP G  V V +Y+L  +   +  
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410

Query: 420 PERYNPQRW-LDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETL-- 476
           PE++ P+R+    + S   + ++PFG G R C+G R A   + L +   L++F  +    
Sbjct: 411 PEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKE 470

Query: 477 TQEDIKMVYSFILRP 491
           TQ  +K+    IL+P
Sbjct: 471 TQIPLKLDNLPILQP 485


>gi|12383060 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 1 [Homo sapiens]
          Length = 504

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 97/380 (25%), Positives = 171/380 (45%), Gaps = 42/380 (11%)

Query: 136 EWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHY 195
           EW+  R  L+P   S K    F  MV  +++     L + + Q A  S +++++     Y
Sbjct: 125 EWKRIRTLLSPAFTSVK----FKEMVPIISQ-CGDMLVRSLRQEAENSKSINLKDFFGAY 179

Query: 196 TIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKE 255
           T++     LFG  L  + +       N    L++ F     L+    SL  +++P     
Sbjct: 180 TMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLI---SLFPFLTPV---- 232

Query: 256 HFEAWDC------IFQYGDNCIQKIYQELAFNRPQHYTGIVAELL----------LKAEL 299
            FEA +       +  +  N I+++ +    ++ +H      +++           KA  
Sbjct: 233 -FEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALS 291

Query: 300 SLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKAT 359
            LE + A S+ +   + DTT+  L   ++ELA +PDVQQ L++E  A   + +     A 
Sbjct: 292 DLELV-AQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL 350

Query: 360 TELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPR 419
            ++  L   + ETLRL+PV   + RV   D+ +    IP G  V V +Y+L  +   +  
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410

Query: 420 PERYNPQRWLDIRGSGRN------FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
           PE++ P+     R S +N      + ++PFG G R C+G R A   + L +   L++F  
Sbjct: 411 PEKFCPES----RFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSF 466

Query: 474 ETL--TQEDIKMVYSFILRP 491
           +    TQ  +K+    IL+P
Sbjct: 467 KPCKETQIPLKLDNLPILQP 486


>gi|13435386 cytochrome P450, family 3, subfamily A, polypeptide 4
           [Homo sapiens]
          Length = 503

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 63/199 (31%), Positives = 104/199 (52%), Gaps = 4/199 (2%)

Query: 296 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 355
           KA   LE +  + + + AG  +TT+  L   ++ELA +PDVQQ L++E  A   + +   
Sbjct: 288 KALSDLELVAQSIIFIFAG-YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPT 346

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAA 415
                ++  L   + ETLRL+P+ + LERV   D+ +    IP G +V +  Y+L R+  
Sbjct: 347 YDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPK 406

Query: 416 LFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVE 474
            +  PE++ P+R+        + + + PFG G R C+G R A   M L L  VL++F  +
Sbjct: 407 YWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFK 466

Query: 475 TL--TQEDIKMVYSFILRP 491
               TQ  +K+    +L+P
Sbjct: 467 PCKETQIPLKLSLGGLLQP 485


>gi|150036266 cytochrome P450, family 4, subfamily F, polypeptide 12
           [Homo sapiens]
          Length = 524

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 62/177 (35%), Positives = 90/177 (50%), Gaps = 4/177 (2%)

Query: 299 LSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE--SLAAAASISEHPQ 356
           LS E I+A +     G  DTTA  L   L+ LAR+P+ Q+  RQE   L       E   
Sbjct: 313 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 372

Query: 357 KATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYH-IPAGTLVQVFLYSLGRNAA 415
               +LP L   +KE+LRL+P   F+ R  + D+VL +   IP G    + +  +  N  
Sbjct: 373 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPT 432

Query: 416 LFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471
           ++P PE Y+P R+      GR+    +PF  G R C+G+  A AEM ++L  +L HF
Sbjct: 433 VWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHF 489


>gi|4503233 cytochrome P450, family 3, subfamily A, polypeptide 7
           [Homo sapiens]
          Length = 503

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 59/193 (30%), Positives = 96/193 (49%), Gaps = 2/193 (1%)

Query: 296 KAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHP 355
           KA   LE +  + + + AG  +TT+  L   ++ELA +PDVQQ +++E      + +   
Sbjct: 288 KALSDLELMAQSIIFIFAG-YETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPT 346

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAA 415
                +L  L   + ETLRL+PV + LERV   D+ +    IP G +V +  Y L  +  
Sbjct: 347 YDTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPK 406

Query: 416 LFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVE 474
            +  PE++ P+R+        + + + PFG G R C+G R A   M L L  VL++F  +
Sbjct: 407 YWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFK 466

Query: 475 TLTQEDIKMVYSF 487
              +  I +   F
Sbjct: 467 PCKETQIPLKLRF 479


>gi|6005737 cytochrome P450, family 4, subfamily F, polypeptide 8
           [Homo sapiens]
          Length = 520

 Score = 87.0 bits (214), Expect = 4e-17
 Identities = 61/180 (33%), Positives = 92/180 (51%), Gaps = 4/180 (2%)

Query: 298 ELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE--SLAAAASISEHP 355
           ELS E I+A +     G  DTTA  L   L+ LAR+P+ Q+  RQE   L       E  
Sbjct: 312 ELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIE 371

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYH-IPAGTLVQVFLYSLGRNA 414
                +LP L   LKE+LRL+P      R  + D+VL +   IP G +  + ++++  N 
Sbjct: 372 WDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNP 431

Query: 415 ALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
           +++P PE Y+P R+       R+    +PF  G R C+G++ A AEM ++L   L  F +
Sbjct: 432 SVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRI 491


>gi|34098959 cytochrome P450, family 2, subfamily U, polypeptide 1
           [Homo sapiens]
          Length = 544

 Score = 86.7 bits (213), Expect = 5e-17
 Identities = 53/164 (32%), Positives = 86/164 (52%), Gaps = 2/164 (1%)

Query: 310 ELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTELPLLRAAL 369
           +L     DTT   LL  L  ++ NPDVQ+ + +E      +          ++P   A +
Sbjct: 348 DLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATI 407

Query: 370 KETLRL-YPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRW 428
            E  RL   V L +  + S + VLQ Y IP GTL+   L+S+ R+ A++ +PE + P R+
Sbjct: 408 MEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRF 467

Query: 429 LDIRGS-GRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471
           LD +G   +    +PFG G R C+G +LA+ E+ L+   +++ F
Sbjct: 468 LDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSF 511


>gi|190570174 cytochrome P450, family 21, subfamily A, polypeptide 2
           isoform b [Homo sapiens]
          Length = 465

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 57/168 (33%), Positives = 85/168 (50%), Gaps = 7/168 (4%)

Query: 308 SMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE---SLAAAASISEHPQKATTELPL 364
           +++L  G  +TTA  L   +  L  +P++QQ L++E    L   AS S  P K    LPL
Sbjct: 256 AVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPL 315

Query: 365 LRAALKETLRLYPV-GLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERY 423
           L A + E LRL PV  L L    +    +  Y IP GT++   L     +  ++ RP  +
Sbjct: 316 LNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF 375

Query: 424 NPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471
            P R+L+    G+N   + FG G R CLG  LA  E+ ++L  +L+ F
Sbjct: 376 WPDRFLE---PGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAF 420


>gi|14550409 cytochrome P450, family 21, subfamily A, polypeptide 2
           isoform a [Homo sapiens]
          Length = 495

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 57/168 (33%), Positives = 85/168 (50%), Gaps = 7/168 (4%)

Query: 308 SMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE---SLAAAASISEHPQKATTELPL 364
           +++L  G  +TTA  L   +  L  +P++QQ L++E    L   AS S  P K    LPL
Sbjct: 286 AVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPL 345

Query: 365 LRAALKETLRLYPV-GLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERY 423
           L A + E LRL PV  L L    +    +  Y IP GT++   L     +  ++ RP  +
Sbjct: 346 LNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEF 405

Query: 424 NPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471
            P R+L+    G+N   + FG G R CLG  LA  E+ ++L  +L+ F
Sbjct: 406 WPDRFLE---PGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>gi|195972898 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 51/163 (31%), Positives = 81/163 (49%), Gaps = 2/163 (1%)

Query: 323 LLMTLFELARNPDVQQ-ILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLF 381
           L    + LA NPD Q+ +LR+  +     ++         LP L   + ETLR+YP    
Sbjct: 351 LSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFR 410

Query: 382 LERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRW-LDIRGSGRNFHH 440
             R  + D  +    IPAG ++++ + +L  +   +P PE +NP+R+  + R   R F +
Sbjct: 411 FTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTY 470

Query: 441 VPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKM 483
           +PFG G R CLG RL   E+ L L HVL  F  +   +  + +
Sbjct: 471 LPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513


>gi|195972896 thromboxane A synthase 1, platelet isoform TXS-I [Homo
           sapiens]
          Length = 534

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 51/163 (31%), Positives = 81/163 (49%), Gaps = 2/163 (1%)

Query: 323 LLMTLFELARNPDVQQ-ILRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLF 381
           L    + LA NPD Q+ +LR+  +     ++         LP L   + ETLR+YP    
Sbjct: 351 LSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFR 410

Query: 382 LERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPRPERYNPQRW-LDIRGSGRNFHH 440
             R  + D  +    IPAG ++++ + +L  +   +P PE +NP+R+  + R   R F +
Sbjct: 411 FTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTY 470

Query: 441 VPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLVETLTQEDIKM 483
           +PFG G R CLG RL   E+ L L HVL  F  +   +  + +
Sbjct: 471 LPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513


>gi|16933535 cytochrome P450, family 3, subfamily A, polypeptide 43
           isoform 3 [Homo sapiens]
          Length = 420

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 77/308 (25%), Positives = 138/308 (44%), Gaps = 30/308 (9%)

Query: 136 EWRFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHY 195
           EW+  R  L+P   S K    F  MV  +++     L + + Q A  S +++++     Y
Sbjct: 125 EWKRIRTLLSPAFTSVK----FKEMVPIISQ-CGDMLVRSLRQEAENSKSINLKDFFGAY 179

Query: 196 TIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKE 255
           T++     LFG  L  + +       N    L++ F     L+    SL  +++P     
Sbjct: 180 TMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLI---SLFPFLTPV---- 232

Query: 256 HFEAWDC------IFQYGDNCIQKIYQELAFNRPQHYTGIVAELL----------LKAEL 299
            FEA +       +  +  N I+++ +    ++ +H      +++           KA  
Sbjct: 233 -FEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALS 291

Query: 300 SLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKAT 359
            LE + A S+ +   + DTT+  L   ++ELA +PDVQQ L++E  A   + +     A 
Sbjct: 292 DLELV-AQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDAL 350

Query: 360 TELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYSLGRNAALFPR 419
            ++  L   + ETLRL+PV   + RV   D+ +    IP G  V V +Y+L  +   +  
Sbjct: 351 VQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTE 410

Query: 420 PERYNPQR 427
           PE++ P+R
Sbjct: 411 PEKFCPER 418


>gi|13435391 cytochrome P450, family 4, subfamily F, polypeptide 2
           [Homo sapiens]
          Length = 520

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 60/180 (33%), Positives = 89/180 (49%), Gaps = 4/180 (2%)

Query: 298 ELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE--SLAAAASISEHP 355
           +LS E I+A +        DTTA  L   L+ LA++P+ Q+  RQE   L       E  
Sbjct: 312 KLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIE 371

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYH-IPAGTLVQVFLYSLGRNA 414
                 LP L   +KE+LRL+P    + R V+ D+VL +   IP G +  + ++    N 
Sbjct: 372 WDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNP 431

Query: 415 ALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
           A++P PE Y+P R+       R+    +PF  G R C+G+  A AEM ++L   L  F V
Sbjct: 432 AVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRV 491


>gi|45267826 cytochrome P450, family 2, subfamily R, polypeptide 1
           [Homo sapiens]
          Length = 501

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 78/303 (25%), Positives = 129/303 (42%), Gaps = 29/303 (9%)

Query: 187 DVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQL-----MFMP 241
           D +  I +     +NL +FGER        +    +F H +E +F   V+L     +F+ 
Sbjct: 178 DFKQLITNAVSNITNLIIFGERF-------TYEDTDFQHMIE-LFSENVELAASASVFLY 229

Query: 242 RSLSRWISPKVWKEH---FEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLKAE 298
            +   WI    + +H   F     ++ +    I+K         PQH+     + + + +
Sbjct: 230 NAFP-WIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGK 288

Query: 299 ------LSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASIS 352
                  S E +  +  EL     +TT   L   +  +A  P++Q  +++E         
Sbjct: 289 NDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNG 348

Query: 353 EHPQKATTELPLLRAALKETLR---LYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
           +       ++P   A L E LR   + P+G+F     S D V++ Y IP GT V   LYS
Sbjct: 349 KPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIF--HATSEDAVVRGYSIPKGTTVITNLYS 406

Query: 410 LGRNAALFPRPERYNPQRWLDIRG-SGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVL 468
           +  +   +  PE ++P+R+LD  G   +    VPF  G R CLG  LA  EM L    +L
Sbjct: 407 VHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALL 466

Query: 469 KHF 471
           + F
Sbjct: 467 QRF 469


>gi|193083180 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 59/180 (32%), Positives = 88/180 (48%), Gaps = 4/180 (2%)

Query: 298 ELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE--SLAAAASISEHP 355
           ELS E I+A +        DTTA  L   L+ LA++P+ Q+  RQE   L       E  
Sbjct: 312 ELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIE 371

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYH-IPAGTLVQVFLYSLGRNA 414
                +LP L   +KE+LRL+P    + R  + D VL +   IP G +  + +  +  N 
Sbjct: 372 WDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNP 431

Query: 415 ALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
            ++P PE Y+P R+       R+    +PF  G R C+G+  A AEM ++L   L HF +
Sbjct: 432 TVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRI 491


>gi|193083178 cytochrome P450 family 4 subfamily F polypeptide 11
           [Homo sapiens]
          Length = 524

 Score = 79.7 bits (195), Expect = 6e-15
 Identities = 59/180 (32%), Positives = 88/180 (48%), Gaps = 4/180 (2%)

Query: 298 ELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQE--SLAAAASISEHP 355
           ELS E I+A +        DTTA  L   L+ LA++P+ Q+  RQE   L       E  
Sbjct: 312 ELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIE 371

Query: 356 QKATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYH-IPAGTLVQVFLYSLGRNA 414
                +LP L   +KE+LRL+P    + R  + D VL +   IP G +  + +  +  N 
Sbjct: 372 WDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNP 431

Query: 415 ALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHFLV 473
            ++P PE Y+P R+       R+    +PF  G R C+G+  A AEM ++L   L HF +
Sbjct: 432 TVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRI 491


>gi|18491008 cytochrome P450, family 2, subfamily J, polypeptide 2
           [Homo sapiens]
          Length = 502

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 109/496 (21%), Positives = 194/496 (39%), Gaps = 44/496 (8%)

Query: 12  AAPWLSLQ-RARALGTRAARAPRTVLPFEAMPQHPGNRW-LRLLQIWREQGYEHLHLEMH 69
           AA W  +  R   LGT A       L       +P   W L  L  +    +E  HLE+ 
Sbjct: 10  AALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQ 69

Query: 70  QTFQELGPIFRYNLGGPRMVCVM-LPEDVEKLQQVDSLHPCRMILEPWVAYRQHRGHKCG 128
              ++ G +F   LG    V +  LP   E L  +D     R    P    R+H   K G
Sbjct: 70  LFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNR----PVTPMREHIFKKNG 125

Query: 129 VFLLNGPEW----RFNRLRLNPDVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGSL 184
           + + +G  W    RF    L    L  K+++     +   A+  ++A+K++         
Sbjct: 126 LIMSSGQAWKEQRRFTLTALRNFGLGKKSLEE---RIQEEAQHLTEAIKEE--------- 173

Query: 185 TLDVQPSIFHYTIE--ASNLAL---FGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMF 239
             + QP   H+ I    SN+     FGER      S     L  L  +  +  S    ++
Sbjct: 174 --NGQPFDPHFKINNAVSNIICSITFGERFEYQD-SWFQQLLKLLDEVTYLEASKTCQLY 230

Query: 240 MPRSLSRWISPKVWKEH---FEAWDCIFQYGDNCIQKIYQELAFNRPQHYTGIVAELLLK 296
              ++  WI   +   H   F  W  +  +  + I K  ++      + +     + + K
Sbjct: 231 ---NVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSK 287

Query: 297 ------AELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAAS 350
                 +    E +  ++++L     +TT+  L   L  +A  P++Q+ ++ E       
Sbjct: 288 HTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQ 347

Query: 351 ISEHPQKATTELPLLRAALKETLRLYPV-GLFLERVVSSDLVLQNYHIPAGTLVQVFLYS 409
             +    A   +P   A + E  R+  +  L + R V+ D  L  YH+P GT++   L +
Sbjct: 348 GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTA 407

Query: 410 LGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLK 469
           L R+   +  P+ +NP  +L+     +    +PF  G R CLG +LA  E+ +    +++
Sbjct: 408 LHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQ 467

Query: 470 HFLVETLTQEDIKMVY 485
            F       E + + +
Sbjct: 468 KFTFRPPNNEKLSLKF 483


>gi|153218662 cytochrome P450, family 4, subfamily B, polypeptide 1
           isoform a [Homo sapiens]
          Length = 512

 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 83/361 (22%), Positives = 150/361 (41%), Gaps = 27/361 (7%)

Query: 128 GVFLLNGPEWRFNRLRLNP----DVLSPKAVQRFLPMVDAVARDFSQALKKKVLQNARGS 183
           G+ +L GP+W  +R  L P    DVL P           AV  + ++ +  K  + AR  
Sbjct: 125 GLLVLEGPKWLQHRKLLTPGFHYDVLKPYV---------AVFTESTRIMLDKWEEKAREG 175

Query: 184 LTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRS 243
            + D+   + H  +       FG     +GHS  S+    +  L ++ +  +        
Sbjct: 176 KSFDIFCDVGHMALNTLMKCTFGRGDTGLGHSRDSSYYLAVSDLTLLMQQRLVSFQYHND 235

Query: 244 LSRWISPKVWKEHFEAWDCIFQYGDNCIQK----IYQELAFNRPQHYTGIVAELLLKAEL 299
              W++P   +    A      + D  I++    +  E    + Q+   +    +L    
Sbjct: 236 FIYWLTPH-GRRFLRACQVAHDHTDQVIRERKAALQDEKVRKKIQNRRHLDFLDILLGAR 294

Query: 300 SLEAIKANSMELTAG-------SVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASIS 352
             + IK +  +L A          DTT   +   L+ +A  P+ Q   R+E         
Sbjct: 295 DEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQD 354

Query: 353 EHPQKATTELPLLRAALKETLRLYPVGLFLERVVSSDLV-LQNYHIPAGTLVQVFLYSLG 411
                   ++  L   +KE+ RLYP    + R +S  +  +    +PAG+L+ + +Y+L 
Sbjct: 355 FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALH 414

Query: 412 RNAALFPRPERYNPQRWLDIRGSGRN-FHHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKH 470
           RN+A++P PE ++  R+     S R+ F  +PF  G R C+G++ A +EM ++    L  
Sbjct: 415 RNSAVWPDPEVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLR 474

Query: 471 F 471
           F
Sbjct: 475 F 475


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,830,692
Number of Sequences: 37866
Number of extensions: 822808
Number of successful extensions: 2441
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 2239
Number of HSP's gapped (non-prelim): 98
length of query: 503
length of database: 18,247,518
effective HSP length: 107
effective length of query: 396
effective length of database: 14,195,856
effective search space: 5621558976
effective search space used: 5621558976
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.