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Search of human proteins with 119220585
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119220585 apical early endosomal glycoprotein precursor
[Homo sapiens]
(1137 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119220585 apical early endosomal glycoprotein precursor [Homo... 2434 0.0
gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Ho... 195 2e-49
gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Ho... 195 2e-49
gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Ho... 193 7e-49
gi|223278413 MAM domain containing 2 [Homo sapiens] 126 1e-28
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 99 2e-20
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 99 2e-20
gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens] 89 2e-17
gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens] 89 2e-17
gi|24111244 MAM domain containing glycosylphosphatidylinositol a... 88 4e-17
gi|223942069 enterokinase precursor [Homo sapiens] 79 2e-14
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 73 2e-12
gi|239755252 PREDICTED: hypothetical protein [Homo sapiens] 64 8e-10
gi|169201936 PREDICTED: hypothetical protein [Homo sapiens] 64 8e-10
gi|169191966 PREDICTED: hypothetical protein [Homo sapiens] 64 8e-10
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 59 3e-08
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 59 3e-08
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 59 3e-08
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 59 3e-08
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 59 3e-08
gi|75709198 nephronectin [Homo sapiens] 57 1e-07
gi|61744471 low density lipoprotein receptor-related protein 8 i... 54 8e-07
gi|65301119 low density lipoprotein receptor-related protein 8 i... 54 8e-07
gi|110735404 protein tyrosine phosphatase, receptor type, U isof... 52 2e-06
gi|110735406 protein tyrosine phosphatase, receptor type, U isof... 52 2e-06
gi|110735402 protein tyrosine phosphatase, receptor type, U isof... 52 2e-06
gi|157419150 protein tyrosine phosphatase, receptor type, M isof... 52 3e-06
gi|157419152 protein tyrosine phosphatase, receptor type, M isof... 52 3e-06
gi|208431815 protein tyrosine phosphatase, receptor type, K isof... 52 4e-06
gi|18860902 protein tyrosine phosphatase, receptor type, K isofo... 52 4e-06
>gi|119220585 apical early endosomal glycoprotein precursor [Homo
sapiens]
Length = 1137
Score = 2434 bits (6309), Expect = 0.0
Identities = 1137/1137 (100%), Positives = 1137/1137 (100%)
Query: 1 MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTL 60
MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTL
Sbjct: 1 MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTL 60
Query: 61 GAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRG 120
GAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRG
Sbjct: 61 GAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRG 120
Query: 121 KEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGW 180
KEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGW
Sbjct: 121 KEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGW 180
Query: 181 QELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKV 240
QELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKV
Sbjct: 181 QELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKV 240
Query: 241 CVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSW 300
CVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSW
Sbjct: 241 CVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSW 300
Query: 301 PRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFL 360
PRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFL
Sbjct: 301 PRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFL 360
Query: 361 QTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILS 420
QTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILS
Sbjct: 361 QTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILS 420
Query: 421 DHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQ 480
DHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQ
Sbjct: 421 DHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQ 480
Query: 481 CAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWG 540
CAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWG
Sbjct: 481 CAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWG 540
Query: 541 QLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHLSDTHWRWVE 600
QLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHLSDTHWRWVE
Sbjct: 541 QLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHLSDTHWRWVE 600
Query: 601 SRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTL 660
SRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTL
Sbjct: 601 SRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTL 660
Query: 661 RLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDD 720
RLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDD
Sbjct: 661 RLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDD 720
Query: 721 VAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMV 780
VAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMV
Sbjct: 721 VAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMV 780
Query: 781 VDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLS 840
VDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLS
Sbjct: 781 VDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLS 840
Query: 841 AHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGL 900
AHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGL
Sbjct: 841 AHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGL 900
Query: 901 CGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWL 960
CGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWL
Sbjct: 901 CGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWL 960
Query: 961 RSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVE 1020
RSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVE
Sbjct: 961 RSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVE 1020
Query: 1021 VASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSA 1080
VASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSA
Sbjct: 1021 VASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSA 1080
Query: 1081 LLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP 1137
LLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP
Sbjct: 1081 LLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP 1137
>gi|239755250 PREDICTED: chromosome 10 open reading frame 112 [Homo
sapiens]
Length = 1542
Score = 195 bits (496), Expect = 2e-49
Identities = 148/545 (27%), Positives = 231/545 (42%), Gaps = 69/545 (12%)
Query: 66 CDFEQDPCGWRD-ISTSGYSWLRD---RAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGK 121
CDFE + C W + IS + W+R A E P DH+L G +M +
Sbjct: 19 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 78
Query: 122 EASTAALRSPTLREAASSCKLRLWYH--AASGDVAELRVELTHGAETLTLWQSTGPWGPG 179
A L+SPT + C L W++ S AEL++ + + ++ +W+ G
Sbjct: 79 LWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQ 138
Query: 180 WQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPP-GHHHCQN 238
W E + GR+ F ++ + G A+DD+ F +C LP P +C H C++
Sbjct: 139 WLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRH 198
Query: 239 -KVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSE----GWSRNHRAG 293
+ C+E +LCD D+CGD +DE + C + +FETG+ W + W+RN +
Sbjct: 199 TRACIEKLRLCDLVDDCGDRTDE--VNCAPELQCNFETGICNWEQDAKDDFDWTRN-QGP 255
Query: 294 GPERPSWPRRDHSRNSAQGSFL-VSVAEPGT---PAILSSPEFQASGTSNCSLVFYQYLS 349
P + P +D++ +A+G +L + +EP A L SP A+ T C+ FY ++
Sbjct: 256 TPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMF 315
Query: 350 GSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG 409
G L ++ + + LL + G G W+R ++I S PFQIL+ G G
Sbjct: 316 GKRIYRLAIYQRIWSDSRGQ---LLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDG 372
Query: 410 --GVVGLDDLILSDHCRPVSEVSTLQP------LPPGPRAPAPQPLPPSSRLQDSCKQGH 461
G + +DDL D TL P LP P P LPP +C
Sbjct: 373 FTGDIAIDDLSFMD--------CTLYPGNLPADLPTPPETSVPVTLPP-----HNCTDNE 419
Query: 462 LAC--GDLCVPPEQLCDFEEQCAGGEDEQAC--GTTDFESPEAGGW---------EDASV 508
C C+ Q CDF+ C DE +C FE W +D++
Sbjct: 420 FICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNT 479
Query: 509 GRLQW---RRVSAQESQGSSAAAAGHFLSLQRAW--------GQLGAEARVLTPLLGPSG 557
R W +S + + + H + W G+ G A +LTP++ +G
Sbjct: 480 FR--WGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG 537
Query: 558 PSCEL 562
P C L
Sbjct: 538 PKCTL 542
Score = 187 bits (475), Expect = 5e-47
Identities = 175/680 (25%), Positives = 271/680 (39%), Gaps = 101/680 (14%)
Query: 28 CRSPGQAV-----CNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDP-CGW------ 75
CRS G + C+F DC D SDEA C C FE+ C W
Sbjct: 422 CRSDGHCIEKMQKCDFKYDCPDKSDEASCVME----------VCSFEKRSLCKWYQPIPV 471
Query: 76 ---RDISTSGYSWLRDRAGAALEGPGPHS---DHTLGTDLGWYMAVGTHRGKEASTAALR 129
+D +T + W + G H DHT T GWY+ + GK TA +
Sbjct: 472 HLLQDSNT--FRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADIL 529
Query: 130 SPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGR 189
+P + C L W H V L+V + T LW TG G W+ V G
Sbjct: 530 TPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLG- 588
Query: 190 IRGDFRVTFSATRNATHRGAVALDDLEFWDCG-LPTPQANCPPGHHHCQNKVCVEPQQLC 248
IR ++ F A R ++ G VA+DD+ F DC L +P+ C C NK C+ +LC
Sbjct: 589 IRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLC 648
Query: 249 DGEDNCGDLSDENPLTC----GRHIATDFETGLGPW--NRSEGWSRNHRAGG-PERPSWP 301
D ++C D SDE C GR DFE L W + E + N +A P + P
Sbjct: 649 DFVNDCADNSDETTFICRTSSGR---CDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEP 705
Query: 302 RRDHSRNSAQGSFL----VSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQ 357
DH+ ++ G ++ + +P A +SSP + + NC ++F+ ++ G+ G L
Sbjct: 706 AADHTLGNSSGHYIFINSLFPQQPMRAARISSPVI-SKRSKNCKIIFHYHMYGNGIGALT 764
Query: 358 LFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG--GVVGLD 415
L ++ + VLL E G W R+ + + FQ+ G+ G G G + LD
Sbjct: 765 LMQVSV---TNQTKVLL-NLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALD 820
Query: 416 DLILSDHCRPVS---EVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC-GDLCVPP 471
D++L+++C + + PLP G C G+ C C
Sbjct: 821 DIVLTENCLSLHDSVQEELAVPLPTG-----------------FCPLGYRECHNGKCYRL 863
Query: 472 EQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGH 531
EQ C+F + C E CG++ GW+++ W V S S H
Sbjct: 864 EQSCNFVDNCGDNTGENKCGSSCTFEKGWCGWQNSQADNFDW--VLGVGSHQSLRPPKDH 921
Query: 532 FLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHL 591
L + A + R P+ S LH ++ +C+ +
Sbjct: 922 TLGNENA---ILLMRRHKYPI-----RSVNLHTVKHVLKAQTVGNCS------------V 961
Query: 592 SDTHWRWVESRGPDHDHTTGQG-----HFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECL 646
S R ++ +++T G HF+ L+ T G AH S ++ +
Sbjct: 962 SKLEARLLDFLSVPNENTFGSSDHMNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTM 1021
Query: 647 SFWYHLHGPQIGTLRLAMRR 666
SFWY + G++++ ++R
Sbjct: 1022 SFWYFISAKATGSIQILIKR 1041
Score = 140 bits (354), Expect = 5e-33
Identities = 149/605 (24%), Positives = 235/605 (38%), Gaps = 128/605 (21%)
Query: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAAL 94
+C+ V DC D +DE C +P L C+FE C W + + W R++
Sbjct: 208 LCDLVDDCGDRTDEVNC-----APEL----QCNFETGICNWEQDAKDDFDWTRNQGPTPT 258
Query: 95 EGPGPHSDHTLGTDLGWYMAVGTHRGKE-ASTAALRSPTLREA-ASSCKLRLWYHAASGD 152
GP D+TLGT G Y+ + + + +AAL SP L C R +YH
Sbjct: 259 LNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKR 318
Query: 153 VAELRV--ELTHGAETLTLWQSTGPWGPGW--QELAVTTGRIRGDFRVTFSATRNATHRG 208
+ L + + + LWQ G G W + L +++ R F++ A+ G
Sbjct: 319 IYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISS---RQPFQILVEASVGDGFTG 375
Query: 209 AVALDDLEFWDC---------GLPTPQA----------NCPPGHHHCQNK-VCVEPQQLC 248
+A+DDL F DC LPTP NC C++ C+E Q C
Sbjct: 376 DIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKC 435
Query: 249 DGEDNCGDLSDE-------------------NPLTCGRHIATD---FETGLGPWNRSEGW 286
D + +C D SDE P+ H+ D F GLG
Sbjct: 436 DFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV--HLLQDSNTFRWGLGNGISIHHG 493
Query: 287 SRNHRAGGPERPSWPRRDHSRNSAQGSFLV---SVAEPGTPAILSSPEFQASGTSNCSLV 343
NHR P DH++N+ G +L S + G A + +P +G C+LV
Sbjct: 494 EENHR---------PSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG-PKCTLV 543
Query: 344 FYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLA 403
F+ +++G+ G LQ+ ++ L + G+ G W R V + QI+
Sbjct: 544 FWTHMNGATVGSLQVLIK-----KDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFR 598
Query: 404 GQTGPG--GVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQD---SCK 458
+ G G V +DD+ D C P+ L P + D C
Sbjct: 599 AKRGISYIGDVAVDDISFQD-CSPL--------------------LSPERKCTDHEFMCA 637
Query: 459 QGHLACGDLCVPPEQLCDFEEQCAGGEDE------QACGTTDFESPEAGGWEDASVGRLQ 512
H C+ ++LCDF CA DE + G DFE + W+
Sbjct: 638 NKH------CIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF-DLCSWKQEKDEDFD 690
Query: 513 WR-RVSAQESQGSSAAA-------AGHFLSLQRAWGQLGAE-ARVLTPLLGPSGPSCELH 563
W + S+ + G+ AA +GH++ + + Q AR+ +P++ +C++
Sbjct: 691 WNLKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPMRAARISSPVISKRSKNCKII 750
Query: 564 LAYYL 568
Y++
Sbjct: 751 FHYHM 755
Score = 103 bits (257), Expect = 9e-22
Identities = 95/401 (23%), Positives = 164/401 (40%), Gaps = 68/401 (16%)
Query: 734 CSFEDSDCGFSPGGQGL---WRRQANASGHAAW---GPPTDHTTETAQGHYMVVDTSPDA 787
C FE + C + G W R + + A + PP DH+ +QGH+M + +
Sbjct: 19 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 78
Query: 788 LPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQ---VLSLSAHGG 844
L Q A L S L+FW++ S G + L H + + + G
Sbjct: 79 L--WQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQG 136
Query: 845 LAWRLGSMDV-QAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS---------- 893
W ++ + + + + + + V+ G+ A+DD+ ++ P P
Sbjct: 137 KQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWC 196
Query: 894 ---------------------------------CDFESGLCGWSHLAWPGLGGYSWDWGG 920
C+FE+G+C W A + W
Sbjct: 197 RHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDA---KDDFDWTRNQ 253
Query: 921 GATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPAS--CLRFWYH 978
G TP+ P D+TLGT GH+ + E+ +A L S L AT RF+YH
Sbjct: 254 GPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYH 313
Query: 979 MGFPEHFYKGELKVLLHS-AQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGG 1037
M F + Y+ + + S ++GQL +W G++ ++W+ + ++S + FQI+ EA++ G
Sbjct: 314 M-FGKRIYRLAIYQRIWSDSRGQL-LWQIFGNQGNRWIRKHLNISSRQPFQILVEASV-G 370
Query: 1038 QPALGPIALDDVEY----LAGQHCQQPAPSPGNTAAPGSVP 1074
G IA+DD+ + L + P+P T+ P ++P
Sbjct: 371 DGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLP 411
Score = 101 bits (252), Expect = 4e-21
Identities = 142/623 (22%), Positives = 219/623 (35%), Gaps = 151/623 (24%)
Query: 577 CNFERDTCSWYPGHLSDTHWRWVES-----------RGPDHDHT--TGQGHFVLLDPTDP 623
C+FE ++C W+ +S H+ W+ S + P DH+ QGHF+ +
Sbjct: 19 CDFEANSCDWFEA-ISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSS 77
Query: 624 LAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGT--LRLAMRREGEETHLWSRSGTQG 681
W A L S P LSFW++ +G +G L+L M + T +W QG
Sbjct: 78 SLW-QVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQG 136
Query: 682 NRWHEAWATLSH--QPGSHAQYQLLFEGLRDGYHGTMALDDV----AVRPGP-------- 727
+W EA L QP H + G+ Y G A+DD+ P P
Sbjct: 137 KQWLEATIQLGRLSQP-FHLSLDKVSLGI---YDGVSAIDDIRFENCTLPLPAESCEGLD 192
Query: 728 -------------------------------CWAPNYCSFEDSDCGFSPGGQG--LWRRQ 754
C C+FE C + + W R
Sbjct: 193 HFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRN 252
Query: 755 ANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWY 814
+ GP D+T TA+GHY+ +++S + A L+ + + F+Y
Sbjct: 253 QGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYY 312
Query: 815 HGSLRSPGTLRVY--LEERGRHQVL-SLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGV 871
H + L +Y + R Q+L + + G W +++ + + ++++ EA
Sbjct: 313 HMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDG 372
Query: 872 AHSYVALDDL-----------LLQDGPCPQPGS--------------------------- 893
+A+DDL L D P P S
Sbjct: 373 FTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKM 432
Query: 894 --CDF---------------------ESGLCGW-----SHLAWPGLGGYSWDWGGGAT-- 923
CDF + LC W HL + W G G +
Sbjct: 433 QKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDS-NTFRWGLGNGISIH 491
Query: 924 -PSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGF 981
+P VDHT T G + + ++ G G A + + + T C L FW HM
Sbjct: 492 HGEENHRPSVDHTQNTTDGWYLYADSS-NGKFGDTADILTPIISLTGPKCTLVFWTHMNG 550
Query: 982 PEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPAL 1041
G L+VL+ +W G + QW A+V + QIVF A G +
Sbjct: 551 AT---VGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAK-RGISYI 606
Query: 1042 GPIALDDVEYLAGQHCQQPAPSP 1064
G +A+DD+ + Q C P SP
Sbjct: 607 GDVAVDDISF---QDC-SPLLSP 625
Score = 101 bits (251), Expect = 5e-21
Identities = 149/631 (23%), Positives = 230/631 (36%), Gaps = 108/631 (17%)
Query: 27 HCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWL 86
HC + + +C+FV DC D SDE +S CDFE D C W+ + W
Sbjct: 640 HCIAKDK-LCDFVNDCADNSDETTFICRTSSGR------CDFEFDLCSWKQEKDEDFDWN 692
Query: 87 RDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAA-LRSPTLREAASSCKLRLW 145
+ G P +DHTLG G Y+ + + ++ AA + SP + + + +CK+
Sbjct: 693 LKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPMRAARISSPVISKRSKNCKIIFH 752
Query: 146 YHAASGDVAELRV-ELTHGAETLTLWQSTGPWGPGW--QELAVTTGRIRGDFRVTFSATR 202
YH + L + +++ +T L T G W +EL++ DF++ F
Sbjct: 753 YHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDE---DFQLKFEGRV 809
Query: 203 NATHRGAVALDDLEFWD------------CGLPTPQANCPPGHHHCQNKVCVEPQQLCD- 249
RG +ALDD+ + +P P CP G+ C N C +Q C+
Sbjct: 810 GKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCNF 869
Query: 250 --------GEDNCGDLSDENPLTCG--RHIATDFETGLGPWN-RSEGWSRNHRAGGPE-- 296
GE+ CG CG A +F+ LG + +S ++H G
Sbjct: 870 VDNCGDNTGENKCGSSCTFEKGWCGWQNSQADNFDWVLGVGSHQSLRPPKDHTLGNENAI 929
Query: 297 ----RPSWPRRDHSRNSAQ--------GSFLVSVAEPGTPAILSSPEFQASGTSNCSLVF 344
R +P R + ++ + G+ VS E LS P G+S+
Sbjct: 930 LLMRRHKYPIRSVNLHTVKHVLKAQTVGNCSVSKLEARLLDFLSVPNENTFGSSDHMNWH 989
Query: 345 YQYLSG-------------------SEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAW 385
+ YL S A C F + A + +L +R G
Sbjct: 990 FMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFISAKATGSIQILIKR----GRRR 1045
Query: 386 VRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEV------STLQPLPPGP 439
R + S P I G GG G R E S L PP
Sbjct: 1046 RRAPNPVLSGSP-TIPRQGSQQLGGWRGGS---ARHRARAFPEPECPRGRSALLKGPPQE 1101
Query: 440 RAPAPQPLPPSSRLQDSCKQ-GHLACGDL-CVPPEQLCDFEEQCAGGEDEQAC------- 490
L + + C + C D C+ LCD++ C+G DE C
Sbjct: 1102 EPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSGRSDEAHCAHYTSTT 1161
Query: 491 GTTDFESPEAGGWEDA------SVGRLQW---RRVSAQESQGSSAAAAG---HFLSLQRA 538
G+ +FE+ +G W A S L W R+ A+ S G HFL + +
Sbjct: 1162 GSCNFET-SSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGSGQHFLYVNSS 1220
Query: 539 WGQLGAEARVLTPLLGPSG-PSCELHLAYYL 568
+ G+ AR+ T P+ C + +Y+
Sbjct: 1221 GSKEGSVARITTSKSFPASLGMCTVRFWFYM 1251
Score = 92.0 bits (227), Expect = 3e-18
Identities = 109/483 (22%), Positives = 179/483 (37%), Gaps = 131/483 (27%)
Query: 577 CNFE-RDTCSWY---PGHL--SDTHWRW-----------VESRGPDHDHT--TGQGHFVL 617
C+FE R C WY P HL +RW E+ P DHT T G ++
Sbjct: 455 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY 514
Query: 618 LDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRS 677
D ++ +G +A +L+ P L FW H++G +G+L++ ++++ + LW+++
Sbjct: 515 ADSSNG-KFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQT 573
Query: 678 GTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRD-GYHGTMALDDVAVRP-GPCWAP---- 731
G QG +W A L G + Q++F R Y G +A+DD++ + P +P
Sbjct: 574 GQQGAQWKRAEVFL----GIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKC 629
Query: 732 ---------NYCSFEDSDCGF-----------------SPGGQGL--------------- 750
+C +D C F S G
Sbjct: 630 TDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDF 689
Query: 751 -WRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC 809
W +A++ A P DHT + GHY+ +++ P + A ++S ++
Sbjct: 690 DWNLKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPM-RAARISSPVISKRSKNCK 748
Query: 810 LTFWYH--GSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAV 867
+ F YH G+ TL +L+L+ G WR + + + +++ FE
Sbjct: 749 IIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGR 808
Query: 868 AAGVAHSYVALDDLLLQD-------------------GPCPQ------------------ 890
+ALDD++L + G CP
Sbjct: 809 VGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCN 868
Query: 891 --------------PGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTL 936
SC FE G CGW + ++DW G + +PP DHTL
Sbjct: 869 FVDNCGDNTGENKCGSSCTFEKGWCGWQNSQ-----ADNFDWVLGVGSHQSLRPPKDHTL 923
Query: 937 GTE 939
G E
Sbjct: 924 GNE 926
Score = 73.9 bits (180), Expect = 8e-13
Identities = 52/162 (32%), Positives = 81/162 (50%), Gaps = 18/162 (11%)
Query: 574 EVSCNFERDTCSWYPGHLSDTHWRWVE------SRGPDHDHT--TGQGHFVLLDPTDPLA 625
E+ CNFE C+W D W + + GP D+T T +GH++ ++ ++P A
Sbjct: 227 ELQCNFETGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQA 286
Query: 626 WGHSAHLLSRPQVPAAPTE--CLSFWYHLHGPQIGTLRLAMR--REGEETHLWSRSGTQG 681
+ SA LLS P + A T+ F+YH+ G +I L + R + LW G QG
Sbjct: 287 FQDSAALLS-PILNATDTKGCTFRFYYHMFGKRIYRLAIYQRIWSDSRGQLLWQIFGNQG 345
Query: 682 NRWHEAWATLSHQPGSHAQYQLLFE-GLRDGYHGTMALDDVA 722
NRW +S S +Q+L E + DG+ G +A+DD++
Sbjct: 346 NRWIRKHLNIS----SRQPFQILVEASVGDGFTGDIAIDDLS 383
Score = 73.6 bits (179), Expect = 1e-12
Identities = 78/336 (23%), Positives = 125/336 (37%), Gaps = 63/336 (18%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
P DHT T G Y+ D+S G TA + + L FW H + + G+L
Sbjct: 499 PSVDHTQNTTDGWYLYADSSNGKF--GDTADILTPIISLTGPKCTLVFWTHMNGATVGSL 556
Query: 825 RVYLEERG-RHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLL 883
+V +++ ++ + + G W+ + + ++VF A VA+DD+
Sbjct: 557 QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF 616
Query: 884 QD-GPCPQP--------------------------------------------GSCDFES 898
QD P P G CDFE
Sbjct: 617 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 676
Query: 899 GLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAA 958
LC W + W+ + P+ +P DHTLG +GH+ F + RAA
Sbjct: 677 DLCSWKQEKDED---FDWNLKASSIPAAGTEPAADHTLGNSSGHYIFINSLFPQQPMRAA 733
Query: 959 WLRSEPLPATPASC-LRFWYHM---GFPEHFYKGELKVLLHSAQGQLAV-WGAGGHRRHQ 1013
+ S + +C + F YHM G G L ++ S Q V + +
Sbjct: 734 RISSPVISKRSKNCKIIFHYHMYGNGI------GALTLMQVSVTNQTKVLLNLTVEQGNF 787
Query: 1014 WLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDV 1049
W ++ + ++FQ+ FE + G+ G IALDD+
Sbjct: 788 WRREELSLFGDEDFQLKFEGRV-GKGQRGDIALDDI 822
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 10/177 (5%)
Query: 892 GSCDFESGLCGWSHLAWPGLGGYS-WDWG-GGATPSRYPQPPVDHTLGTEAGHFAFFETG 949
GSC+FE+ W+ DW G P++ P DHT G+ HF + +
Sbjct: 1162 GSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGS-GQHFLYVNSS 1220
Query: 950 VLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSAQG-QLAVWGAG 1007
G A S+ PA+ C +RFW++M P G LKV G + VW
Sbjct: 1221 GSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSM--GILKVYTIEESGLNILVWSVI 1278
Query: 1008 GHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSP 1064
G++R W V ++S F++ FEA L G + IALDD+ + C P P
Sbjct: 1279 GNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIF-IALDDISFT--PECVTGGPVP 1332
Score = 61.6 bits (148), Expect = 4e-09
Identities = 61/240 (25%), Positives = 98/240 (40%), Gaps = 21/240 (8%)
Query: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWR---DISTSGYSWLRDRAG 91
+C++ DC SDEA C ++ + T G +C+FE W ++ L G
Sbjct: 1138 LCDYKPDCSGRSDEAHCAHY--TSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIG 1192
Query: 92 AALEGPG--PHSDHTLGTDLGWYMAVGTHRGKEASTAAL-RSPTLREAASSCKLRLWYHA 148
+ + P SDHT G+ ++ V + KE S A + S + + C +R W++
Sbjct: 1193 SRIPAKALIPDSDHTPGSG-QHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYM 1251
Query: 149 AS-GDVAELRV-ELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATH 206
+ L+V + + +W G GW +V F+V F A +
Sbjct: 1252 IDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSS-NSPFKVAFEADLDGNE 1310
Query: 207 RGAVALDDLEFW-DC----GLPTPQANCPPGHHHC-QNKVCVEPQQLCDGEDNCGDLSDE 260
+ALDD+ F +C +P + C C CV CDG ++C D SDE
Sbjct: 1311 DIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE 1370
Score = 59.3 bits (142), Expect = 2e-08
Identities = 98/437 (22%), Positives = 155/437 (35%), Gaps = 86/437 (19%)
Query: 101 SDHTLGTD--LGWYMAV--GTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAEL 156
+++T G+ + W+ T G A RS RE++++C + WY ++ +
Sbjct: 976 NENTFGSSDHMNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFISAKATGSI 1035
Query: 157 RVELTHG-----AETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVA 211
++ + G A L S G Q+L G F R A+
Sbjct: 1036 QILIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALL 1095
Query: 212 LDDLEFWDCGLPTPQAN--------------CPP-GHHHCQNKVCVEPQQLCDGEDNCGD 256
G P + N CP C++K C+ LCD + +C
Sbjct: 1096 K--------GPPQEEPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSG 1147
Query: 257 LSDENPLTCGRHIAT----DFETGLGPWNRSEG----------WSRNHRAGGPERPSWPR 302
SDE C + +T +FET G W + W+ R P + P
Sbjct: 1148 RSDE--AHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRI--PAKALIPD 1203
Query: 303 RDHSRNSAQGSFLVSVA---EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEA-GCLQL 358
DH+ S Q V+ + E I +S F AS C++ F+ Y+ + G L++
Sbjct: 1204 SDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPAS-LGMCTVRFWFYMIDPRSMGILKV 1262
Query: 359 F-LQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILL-AGQTGPGGV-VGLD 415
+ ++ G +L+ G T W V + S PF++ A G + + LD
Sbjct: 1263 YTIEESGLN-----ILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALD 1317
Query: 416 DLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDL--CVPPEQ 473
D+ + C + GP P P C+ +C CVP
Sbjct: 1318 DISFTPEC-----------VTGGPVPVQPSP----------CEADQFSCIYTLQCVPLSG 1356
Query: 474 LCDFEEQCAGGEDEQAC 490
CD E C G DE C
Sbjct: 1357 KCDGHEDCIDGSDEMDC 1373
Score = 57.8 bits (138), Expect = 6e-08
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 13/147 (8%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC-LTFWYHG-SLRSPG 822
P +DHT + Q H++ V++S G A +T+ + P + C + FW++ RS G
Sbjct: 1202 PDSDHTPGSGQ-HFLYVNSSGSK--EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMG 1258
Query: 823 TLRVYLEERGRHQVLSLSAHGG--LAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDD 880
L+VY E +L S G W GS+ + + ++V FEA G ++ALDD
Sbjct: 1259 ILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDD 1318
Query: 881 L-----LLQDGPCP-QPGSCDFESGLC 901
+ + GP P QP C+ + C
Sbjct: 1319 ISFTPECVTGGPVPVQPSPCEADQFSC 1345
Score = 56.2 bits (134), Expect = 2e-07
Identities = 56/213 (26%), Positives = 86/213 (40%), Gaps = 34/213 (15%)
Query: 556 SGPSCELHLAYYLQSQPREVSCNFERDT------CSWYPGHLSDTHWRW-----VESRGP 604
SG S E H A+Y + SCNFE + CS D W ++ P
Sbjct: 1146 SGRSDEAHCAHYTSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIP 1202
Query: 605 DHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTEC-LSFWYHLHGPQ-IGTLRL 662
D DHT G G L + G A + + PA+ C + FW+++ P+ +G L++
Sbjct: 1203 DSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKV 1262
Query: 663 -AMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGT-MALDD 720
+ G +WS G + W LS S++ +++ FE DG +ALDD
Sbjct: 1263 YTIEESGLNILVWSVIGNKRTGWTYGSVPLS----SNSPFKVAFEADLDGNEDIFIALDD 1318
Query: 721 VA------------VRPGPCWAPNYCSFEDSDC 741
++ V+P PC A + C
Sbjct: 1319 ISFTPECVTGGPVPVQPSPCEADQFSCIYTLQC 1351
Score = 33.1 bits (74), Expect = 1.5
Identities = 30/124 (24%), Positives = 46/124 (37%), Gaps = 21/124 (16%)
Query: 494 DFESPEAGGWEDASVGRLQWRRVSAQESQG-----------SSAAAAGHFLSLQRAWGQL 542
DFE+ +E S W R S E S A+ GHF+ + + L
Sbjct: 20 DFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSL 79
Query: 543 GAEARVLTPLLGPSGPSCELHLAYY---LQSQPREVSCNFERDTCSWYPGHLSDTHWRWV 599
A++ +P +GP C L +Y L E+ + E H S WR +
Sbjct: 80 WQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMEN-------SHDSTVIWRVL 132
Query: 600 ESRG 603
++G
Sbjct: 133 YNQG 136
>gi|239749752 PREDICTED: chromosome 10 open reading frame 112 [Homo
sapiens]
Length = 1817
Score = 195 bits (496), Expect = 2e-49
Identities = 148/545 (27%), Positives = 231/545 (42%), Gaps = 69/545 (12%)
Query: 66 CDFEQDPCGWRD-ISTSGYSWLRD---RAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGK 121
CDFE + C W + IS + W+R A E P DH+L G +M +
Sbjct: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
Query: 122 EASTAALRSPTLREAASSCKLRLWYH--AASGDVAELRVELTHGAETLTLWQSTGPWGPG 179
A L+SPT + C L W++ S AEL++ + + ++ +W+ G
Sbjct: 354 LWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQ 413
Query: 180 WQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPP-GHHHCQN 238
W E + GR+ F ++ + G A+DD+ F +C LP P +C H C++
Sbjct: 414 WLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRH 473
Query: 239 -KVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSE----GWSRNHRAG 293
+ C+E +LCD D+CGD +DE + C + +FETG+ W + W+RN +
Sbjct: 474 TRACIEKLRLCDLVDDCGDRTDE--VNCAPELQCNFETGICNWEQDAKDDFDWTRN-QGP 530
Query: 294 GPERPSWPRRDHSRNSAQGSFL-VSVAEPGT---PAILSSPEFQASGTSNCSLVFYQYLS 349
P + P +D++ +A+G +L + +EP A L SP A+ T C+ FY ++
Sbjct: 531 TPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMF 590
Query: 350 GSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG 409
G L ++ + + LL + G G W+R ++I S PFQIL+ G G
Sbjct: 591 GKRIYRLAIYQRIWSDSRGQ---LLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDG 647
Query: 410 --GVVGLDDLILSDHCRPVSEVSTLQP------LPPGPRAPAPQPLPPSSRLQDSCKQGH 461
G + +DDL D TL P LP P P LPP +C
Sbjct: 648 FTGDIAIDDLSFMD--------CTLYPGNLPADLPTPPETSVPVTLPP-----HNCTDNE 694
Query: 462 LAC--GDLCVPPEQLCDFEEQCAGGEDEQAC--GTTDFESPEAGGW---------EDASV 508
C C+ Q CDF+ C DE +C FE W +D++
Sbjct: 695 FICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNT 754
Query: 509 GRLQW---RRVSAQESQGSSAAAAGHFLSLQRAW--------GQLGAEARVLTPLLGPSG 557
R W +S + + + H + W G+ G A +LTP++ +G
Sbjct: 755 FR--WGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG 812
Query: 558 PSCEL 562
P C L
Sbjct: 813 PKCTL 817
Score = 187 bits (475), Expect = 5e-47
Identities = 175/680 (25%), Positives = 271/680 (39%), Gaps = 101/680 (14%)
Query: 28 CRSPGQAV-----CNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDP-CGW------ 75
CRS G + C+F DC D SDEA C C FE+ C W
Sbjct: 697 CRSDGHCIEKMQKCDFKYDCPDKSDEASCVME----------VCSFEKRSLCKWYQPIPV 746
Query: 76 ---RDISTSGYSWLRDRAGAALEGPGPHS---DHTLGTDLGWYMAVGTHRGKEASTAALR 129
+D +T + W + G H DHT T GWY+ + GK TA +
Sbjct: 747 HLLQDSNT--FRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADIL 804
Query: 130 SPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGR 189
+P + C L W H V L+V + T LW TG G W+ V G
Sbjct: 805 TPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLG- 863
Query: 190 IRGDFRVTFSATRNATHRGAVALDDLEFWDCG-LPTPQANCPPGHHHCQNKVCVEPQQLC 248
IR ++ F A R ++ G VA+DD+ F DC L +P+ C C NK C+ +LC
Sbjct: 864 IRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLC 923
Query: 249 DGEDNCGDLSDENPLTC----GRHIATDFETGLGPW--NRSEGWSRNHRAGG-PERPSWP 301
D ++C D SDE C GR DFE L W + E + N +A P + P
Sbjct: 924 DFVNDCADNSDETTFICRTSSGR---CDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEP 980
Query: 302 RRDHSRNSAQGSFL----VSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQ 357
DH+ ++ G ++ + +P A +SSP + + NC ++F+ ++ G+ G L
Sbjct: 981 AADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVI-SKRSKNCKIIFHYHMYGNGIGALT 1039
Query: 358 LFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG--GVVGLD 415
L ++ + VLL E G W R+ + + FQ+ G+ G G G + LD
Sbjct: 1040 LMQVSV---TNQTKVLL-NLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALD 1095
Query: 416 DLILSDHCRPVS---EVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC-GDLCVPP 471
D++L+++C + + PLP G C G+ C C
Sbjct: 1096 DIVLTENCLSLHDSVQEELAVPLPTG-----------------FCPLGYRECHNGKCYRL 1138
Query: 472 EQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGH 531
EQ C+F + C E CG++ GW+++ W V S S H
Sbjct: 1139 EQSCNFVDNCGDNTGENKCGSSCTFEKGWCGWQNSQADNFDW--VLGVGSHQSLRPPKDH 1196
Query: 532 FLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHL 591
L + A + R P+ S LH ++ +C+ +
Sbjct: 1197 TLGNENA---ILLMRRHKYPI-----RSVNLHTVKHVLKAQTVGNCS------------V 1236
Query: 592 SDTHWRWVESRGPDHDHTTGQG-----HFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECL 646
S R ++ +++T G HF+ L+ T G AH S ++ +
Sbjct: 1237 SKLEARLLDFLSVPNENTFGSSDHMNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTM 1296
Query: 647 SFWYHLHGPQIGTLRLAMRR 666
SFWY + G++++ ++R
Sbjct: 1297 SFWYFISAKATGSIQILIKR 1316
Score = 141 bits (355), Expect = 4e-33
Identities = 149/605 (24%), Positives = 236/605 (39%), Gaps = 128/605 (21%)
Query: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAAL 94
+C+ V DC D +DE C +P L C+FE C W + + W R++
Sbjct: 483 LCDLVDDCGDRTDEVNC-----APEL----QCNFETGICNWEQDAKDDFDWTRNQGPTPT 533
Query: 95 EGPGPHSDHTLGTDLGWYMAVGTHRGKE-ASTAALRSPTLREA-ASSCKLRLWYHAASGD 152
GP D+TLGT G Y+ + + + +AAL SP L C R +YH
Sbjct: 534 LNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKR 593
Query: 153 VAELRV--ELTHGAETLTLWQSTGPWGPGW--QELAVTTGRIRGDFRVTFSATRNATHRG 208
+ L + + + LWQ G G W + L +++ R F++ A+ G
Sbjct: 594 IYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISS---RQPFQILVEASVGDGFTG 650
Query: 209 AVALDDLEFWDC---------GLPTPQA----------NCPPGHHHCQNK-VCVEPQQLC 248
+A+DDL F DC LPTP NC C++ C+E Q C
Sbjct: 651 DIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKC 710
Query: 249 DGEDNCGDLSDE-------------------NPLTCGRHIATD---FETGLGPWNRSEGW 286
D + +C D SDE P+ H+ D F GLG
Sbjct: 711 DFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV--HLLQDSNTFRWGLGNGISIHHG 768
Query: 287 SRNHRAGGPERPSWPRRDHSRNSAQGSFLV---SVAEPGTPAILSSPEFQASGTSNCSLV 343
NHR P DH++N+ G +L S + G A + +P +G C+LV
Sbjct: 769 EENHR---------PSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG-PKCTLV 818
Query: 344 FYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLA 403
F+ +++G+ G LQ+ ++ L + G+ G W R V + QI+
Sbjct: 819 FWTHMNGATVGSLQVLIK-----KDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFR 873
Query: 404 GQTGPG--GVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQD---SCK 458
+ G G V +DD+ D C P+ L P + D C
Sbjct: 874 AKRGISYIGDVAVDDISFQD-CSPL--------------------LSPERKCTDHEFMCA 912
Query: 459 QGHLACGDLCVPPEQLCDFEEQCAGGEDE------QACGTTDFESPEAGGWEDASVGRLQ 512
H C+ ++LCDF CA DE + G DFE + W+
Sbjct: 913 NKH------CIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF-DLCSWKQEKDEDFD 965
Query: 513 WR-RVSAQESQGSSAAA-------AGHFLSLQRAWGQLGAE-ARVLTPLLGPSGPSCELH 563
W + S+ + G+ AA +GH++ ++ + Q AR+ +P++ +C++
Sbjct: 966 WNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKII 1025
Query: 564 LAYYL 568
Y++
Sbjct: 1026 FHYHM 1030
Score = 135 bits (339), Expect = 3e-31
Identities = 142/591 (24%), Positives = 238/591 (40%), Gaps = 105/591 (17%)
Query: 573 REVSCNFERDTCSWYPGHLSDTHWRWV------ESRGPDHDHTTGQGH--FVLLDPT-DP 623
+ ++C+FE C W P D+HW+ + E P DHT H F+ L+ P
Sbjct: 112 KHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSP 171
Query: 624 LAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQG-- 681
+ +L++ + P + + FWYHL Q L + R T L QG
Sbjct: 172 GVAKLGSPVLTKLLTASTPCQ-VQFWYHLS--QHSNLSVFTR-----TSLDGNLQKQGKI 223
Query: 682 -----NRWHEAWATLSHQPG-SHAQYQLLFEGLRDGYHGTMALDDVAV------------ 723
++W A L + G S +QL+ E + T+ALDD++V
Sbjct: 224 IRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLP 283
Query: 724 RPGPCWAPNYCSFEDSDCGFSPGGQGL---WRRQANASGHAAW---GPPTDHTTETAQGH 777
R + C FE + C + G W R + + A + PP DH+ +QGH
Sbjct: 284 RTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGH 343
Query: 778 YMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQ-- 835
+M + +L Q A L S L+FW++ S G + L H
Sbjct: 344 FMFILKKSSSL--WQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDST 401
Query: 836 -VLSLSAHGGLAWRLGSMDV-QAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS 893
+ + + G W ++ + + + + + + V+ G+ A+DD+ ++ P P
Sbjct: 402 VIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAE 461
Query: 894 -------------------------------------------CDFESGLCGWSHLAWPG 910
C+FE+G+C W A
Sbjct: 462 SCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDA--- 518
Query: 911 LGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPA 970
+ W G TP+ P D+TLGT GH+ + E+ +A L S L AT
Sbjct: 519 KDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDT 578
Query: 971 S--CLRFWYHMGFPEHFYKGELKVLLHS-AQGQLAVWGAGGHRRHQWLEAQVEVASAKEF 1027
RF+YHM F + Y+ + + S ++GQL +W G++ ++W+ + ++S + F
Sbjct: 579 KGCTFRFYYHM-FGKRIYRLAIYQRIWSDSRGQL-LWQIFGNQGNRWIRKHLNISSRQPF 636
Query: 1028 QIVFEATLGGQPALGPIALDDVEY----LAGQHCQQPAPSPGNTAAPGSVP 1074
QI+ EA++ G G IA+DD+ + L + P+P T+ P ++P
Sbjct: 637 QILVEASV-GDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLP 686
Score = 103 bits (256), Expect = 1e-21
Identities = 154/667 (23%), Positives = 235/667 (35%), Gaps = 159/667 (23%)
Query: 541 QLGAEARVL----TPLLGPSGPSCELHLAYY----LQSQPREVSCNFERDTCSWYPGHLS 592
QL EA VL T L S E ++Y +Q + C+FE ++C W+ +S
Sbjct: 250 QLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEA-IS 308
Query: 593 DTHWRWV-----------ESRGPDHDHT--TGQGHFVLLDPTDPLAWGHSAHLLSRPQVP 639
H+ W+ E + P DH+ QGHF+ + W A L S
Sbjct: 309 GDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLW-QVAKLQSPTFSQ 367
Query: 640 AAPTECLSFWYHLHGPQIGT--LRLAMRREGEETHLWSRSGTQGNRWHEAWATLSH--QP 695
P LSFW++ +G +G L+L M + T +W QG +W EA L QP
Sbjct: 368 TGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQP 427
Query: 696 GSHAQYQLLFEGLRDGYHGTMALDDV----AVRPGP------------------------ 727
H + G+ Y G A+DD+ P P
Sbjct: 428 -FHLSLDKVSLGI---YDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRL 483
Query: 728 ---------------CWAPNYCSFEDSDCGFSPGGQG--LWRRQANASGHAAWGPPTDHT 770
C C+FE C + + W R + GP D+T
Sbjct: 484 CDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNT 543
Query: 771 TETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVY--L 828
TA+GHY+ +++S + A L+ + + F+YH + L +Y +
Sbjct: 544 LGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRI 603
Query: 829 EERGRHQVL-SLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDL------ 881
R Q+L + + G W +++ + + ++++ EA +A+DDL
Sbjct: 604 WSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCT 663
Query: 882 -----LLQDGPCPQPGS-----------------------------CDF----------- 896
L D P P S CDF
Sbjct: 664 LYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA 723
Query: 897 ----------ESGLCGW-----SHLAWPGLGGYSWDWGGGAT---PSRYPQPPVDHTLGT 938
+ LC W HL + W G G + +P VDHT T
Sbjct: 724 SCVMEVCSFEKRSLCKWYQPIPVHLLQDS-NTFRWGLGNGISIHHGEENHRPSVDHTQNT 782
Query: 939 EAGHFAFFETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSA 997
G + + ++ G G A + + + T C L FW HM G L+VL+
Sbjct: 783 TDGWYLYADSS-NGKFGDTADILTPIISLTGPKCTLVFWTHMNGAT---VGSLQVLIKKD 838
Query: 998 QGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHC 1057
+W G + QW A+V + QIVF A G +G +A+DD+ + Q C
Sbjct: 839 NVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAK-RGISYIGDVAVDDISF---QDC 894
Query: 1058 QQPAPSP 1064
P SP
Sbjct: 895 -SPLLSP 900
Score = 95.9 bits (237), Expect = 2e-19
Identities = 105/429 (24%), Positives = 166/429 (38%), Gaps = 76/429 (17%)
Query: 194 FRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDN 253
F++ F T + R +ALD L + CG + C C + C+ + +CD +
Sbjct: 40 FKIIFEGTL-LSQRSFIALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQD 98
Query: 254 CGDLSDENPLTCGRHIATDFETGLGPW----NRSEGWSRNHRAGGPERPSWPRRDHSRNS 309
C D SDE+P TC +H+ DFE+G W W E +P DH+ N
Sbjct: 99 CSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEH-HFPAADHTANI 157
Query: 310 AQGSFLVSVAE--PGTPAILSSPEFQ--ASGTSNCSLVFYQYLSGSEAGCLQLFLQT-LG 364
GSF+ A+ PG A L SP + ++ C + F+ +L S+ L +F +T L
Sbjct: 158 NHGSFIYLEAQRSPGV-AKLGSPVLTKLLTASTPCQVQFWYHL--SQHSNLSVFTRTSLD 214
Query: 365 PGAPRAPVLLRRRRGELGTAWVRDRVDI-----QSAYPFQILL-AGQTGPGGVVGLDDLI 418
+ ++R + W ++D+ +S PFQ++L A V LDD+
Sbjct: 215 GNLQKQGKIIRFSESQ----WSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDIS 270
Query: 419 LSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFE 478
+S C E+S + LP +S K CDFE
Sbjct: 271 VSQEC----EISY-------------KSLPRTSTQSKFSK----------------CDFE 297
Query: 479 EQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWR-RVSAQESQGSSAAAAGHFLSLQR 537
+C + S + W +S L A S A+ GHF+ + +
Sbjct: 298 --------ANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILK 349
Query: 538 AWGQLGAEARVLTPLLGPSGPSCELHLAYY---LQSQPREVSCNFERDTCSWYPGHLSDT 594
L A++ +P +GP C L +Y L E+ + E H S
Sbjct: 350 KSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMEN-------SHDSTV 402
Query: 595 HWRWVESRG 603
WR + ++G
Sbjct: 403 IWRVLYNQG 411
Score = 91.3 bits (225), Expect = 5e-18
Identities = 109/483 (22%), Positives = 178/483 (36%), Gaps = 131/483 (27%)
Query: 577 CNFE-RDTCSWY---PGHL--SDTHWRW-----------VESRGPDHDHT--TGQGHFVL 617
C+FE R C WY P HL +RW E+ P DHT T G ++
Sbjct: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY 789
Query: 618 LDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRS 677
D ++ +G +A +L+ P L FW H++G +G+L++ ++++ + LW+++
Sbjct: 790 ADSSNG-KFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQT 848
Query: 678 GTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRD-GYHGTMALDDVAVRP-GPCWAP---- 731
G QG +W A L G + Q++F R Y G +A+DD++ + P +P
Sbjct: 849 GQQGAQWKRAEVFL----GIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKC 904
Query: 732 ---------NYCSFEDSDCGF-----------------SPGGQGL--------------- 750
+C +D C F S G
Sbjct: 905 TDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDF 964
Query: 751 -WRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC 809
W +A++ A P DHT + GHY+ + + P + A ++S ++
Sbjct: 965 DWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPM-RAARISSPVISKRSKNCK 1023
Query: 810 LTFWYH--GSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAV 867
+ F YH G+ TL +L+L+ G WR + + + +++ FE
Sbjct: 1024 IIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGR 1083
Query: 868 AAGVAHSYVALDDLLLQD-------------------GPCPQ------------------ 890
+ALDD++L + G CP
Sbjct: 1084 VGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCN 1143
Query: 891 --------------PGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTL 936
SC FE G CGW + ++DW G + +PP DHTL
Sbjct: 1144 FVDNCGDNTGENKCGSSCTFEKGWCGWQNSQ-----ADNFDWVLGVGSHQSLRPPKDHTL 1198
Query: 937 GTE 939
G E
Sbjct: 1199 GNE 1201
Score = 80.5 bits (197), Expect = 8e-15
Identities = 136/569 (23%), Positives = 210/569 (36%), Gaps = 102/569 (17%)
Query: 33 QAVCNFVCDCRDCSDE--AQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRA 90
++VC+ DC D SDE A C H CDFE CGW T W +
Sbjct: 90 ESVCDSRQDCSDESDEDPATCSKH---------LTCDFESGFCGWEPFLTEDSHWKLMKG 140
Query: 91 GAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLRE---AASSCKLRLWYH 147
E P +DHT + G ++ + R A L SP L + A++ C+++ WYH
Sbjct: 141 LNNGEHHFPAADHTANINHGSFIYLEAQR--SPGVAKLGSPVLTKLLTASTPCQVQFWYH 198
Query: 148 AASGDVAEL--RVELTHGAET--LTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRN 203
+ + R L + + S W +L G F++ AT
Sbjct: 199 LSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVL 258
Query: 204 ATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPL 263
+++ VALDD+ + C + CD E N D +
Sbjct: 259 SSN-ATVALDDI--------SVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFE---A 306
Query: 264 TCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGT 323
G H W RS S++ + E + P RDHS N++QG F+ + + +
Sbjct: 307 ISGDHF---------DWIRS---SQSELSADFEHQA-PPRDHSLNASQGHFMFILKKSSS 353
Query: 324 ---PAILSSPEFQASGTSNCSLVFYQYLSGSEAGC--LQLFLQTLGPGAPRAPVLLRRRR 378
A L SP F +G C L F+ Y G G LQL ++ VL +
Sbjct: 354 LWQVAKLQSPTFSQTG-PGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQ-- 410
Query: 379 GELGTAWVRDRVDI-QSAYPFQILLAGQTGPG---GVVGLDDLILSDHCRPVSEVSTLQP 434
G W+ + + + + PF + L + G GV +DD I ++C TL P
Sbjct: 411 ---GKQWLEATIQLGRLSQPFHLSL-DKVSLGIYDGVSAIDD-IRFENC-------TL-P 457
Query: 435 LPPGPRAPAPQPLPPSSRLQDSCK-QGHLACGD--LCVPPEQLCDFEEQCAGGEDEQACG 491
LP +SC+ H C C+ +LCD + C DE C
Sbjct: 458 LP-----------------AESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA 500
Query: 492 TTDFESPEAG--GWEDASVGRLQWRR--------VSAQESQGSSAAAAGHFLSLQRAWGQ 541
+ E G WE + W R + + A GH+L ++ + Q
Sbjct: 501 PELQCNFETGICNWEQDAKDDFDWTRNQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQ 560
Query: 542 LGAE-ARVLTPLLGPSG-PSCELHLAYYL 568
+ A +L+P+L + C Y++
Sbjct: 561 AFQDSAALLSPILNATDTKGCTFRFYYHM 589
Score = 75.9 bits (185), Expect = 2e-13
Identities = 86/384 (22%), Positives = 150/384 (39%), Gaps = 75/384 (19%)
Query: 725 PGPCWAPNYCSFEDSDCGFSP--GGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVD 782
P C C FE CG+ P W+ + P DHT G ++ ++
Sbjct: 107 PATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLE 166
Query: 783 T--SPDALPRGQ---TASLTSKEHRPLAQPACLTFWYH----------------GSLRSP 821
SP G T LT+ + P + FWYH G+L+
Sbjct: 167 AQRSPGVAKLGSPVLTKLLTA------STPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQ 220
Query: 822 GTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDL 881
G + + E + H + L A G ++ ++++ EA +++ VALDD+
Sbjct: 221 GKIIRFSESQWSHAKIDLIAEAG----------ESTLPFQLILEATVLS-SNATVALDDI 269
Query: 882 ------------LLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPS---- 925
L + + CDFE+ C W + + G +DW +
Sbjct: 270 SVSQECEISYKSLPRTSTQSKFSKCDFEANSCDW----FEAISGDHFDWIRSSQSELSAD 325
Query: 926 -RYPQPPVDHTLGTEAGHFAFF--ETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGF 981
+ PP DH+L GHF F ++ L + A L+S T C L FW++ +
Sbjct: 326 FEHQAPPRDHSLNASQGHFMFILKKSSSLW---QVAKLQSPTFSQTGPGCILSFWFY-NY 381
Query: 982 PEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVAS-AKEFQIVFE-ATLGGQP 1039
EL++ + ++ +W ++ QWLEA +++ ++ F + + +LG
Sbjct: 382 GLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYD 441
Query: 1040 ALGPIALDDVEYLAGQHCQQPAPS 1063
G A+DD+ + ++C P P+
Sbjct: 442 --GVSAIDDIRF---ENCTLPLPA 460
Score = 73.9 bits (180), Expect = 8e-13
Identities = 78/336 (23%), Positives = 126/336 (37%), Gaps = 63/336 (18%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
P DHT T G Y+ D+S G TA + + L FW H + + G+L
Sbjct: 774 PSVDHTQNTTDGWYLYADSSNGKF--GDTADILTPIISLTGPKCTLVFWTHMNGATVGSL 831
Query: 825 RVYLEERG-RHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLL 883
+V +++ ++ + + G W+ + + ++VF A VA+DD+
Sbjct: 832 QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF 891
Query: 884 QD-GPCPQP--------------------------------------------GSCDFES 898
QD P P G CDFE
Sbjct: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 951
Query: 899 GLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAA 958
LC W + W+ + P+ +P DHTLG +GH+ F ++ RAA
Sbjct: 952 DLCSWKQEKDED---FDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAA 1008
Query: 959 WLRSEPLPATPASC-LRFWYHM---GFPEHFYKGELKVLLHSAQGQLAV-WGAGGHRRHQ 1013
+ S + +C + F YHM G G L ++ S Q V + +
Sbjct: 1009 RISSPVISKRSKNCKIIFHYHMYGNGI------GALTLMQVSVTNQTKVLLNLTVEQGNF 1062
Query: 1014 WLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDV 1049
W ++ + ++FQ+ FE + G+ G IALDD+
Sbjct: 1063 WRREELSLFGDEDFQLKFEGRV-GKGQRGDIALDDI 1097
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 10/177 (5%)
Query: 892 GSCDFESGLCGWSHLAWPGLGGYS-WDWG-GGATPSRYPQPPVDHTLGTEAGHFAFFETG 949
GSC+FE+ W+ DW G P++ P DHT G+ HF + +
Sbjct: 1437 GSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGS-GQHFLYVNSS 1495
Query: 950 VLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSAQG-QLAVWGAG 1007
G A S+ PA+ C +RFW++M P G LKV G + VW
Sbjct: 1496 GSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSM--GILKVYTIEESGLNILVWSVI 1553
Query: 1008 GHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSP 1064
G++R W V ++S F++ FEA L G + IALDD+ + C P P
Sbjct: 1554 GNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIF-IALDDISFT--PECVTGGPVP 1607
Score = 64.3 bits (155), Expect = 6e-10
Identities = 62/240 (25%), Positives = 99/240 (41%), Gaps = 21/240 (8%)
Query: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWR---DISTSGYSWLRDRAG 91
+C++ DC D SDEA C ++ + T G +C+FE W ++ L G
Sbjct: 1413 LCDYKPDCSDRSDEAHCAHY--TSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIG 1467
Query: 92 AALEGPG--PHSDHTLGTDLGWYMAVGTHRGKEASTAAL-RSPTLREAASSCKLRLWYHA 148
+ + P SDHT G+ ++ V + KE S A + S + + C +R W++
Sbjct: 1468 SRIPAKALIPDSDHTPGSG-QHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYM 1526
Query: 149 AS-GDVAELRV-ELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATH 206
+ L+V + + +W G GW +V F+V F A +
Sbjct: 1527 IDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSS-NSPFKVAFEADLDGNE 1585
Query: 207 RGAVALDDLEFW-DC----GLPTPQANCPPGHHHC-QNKVCVEPQQLCDGEDNCGDLSDE 260
+ALDD+ F +C +P + C C CV CDG ++C D SDE
Sbjct: 1586 DIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE 1645
Score = 61.6 bits (148), Expect = 4e-09
Identities = 99/437 (22%), Positives = 156/437 (35%), Gaps = 86/437 (19%)
Query: 101 SDHTLGTD--LGWYMAV--GTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAEL 156
+++T G+ + W+ T G A RS RE++++C + WY ++ +
Sbjct: 1251 NENTFGSSDHMNWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFISAKATGSI 1310
Query: 157 RVELTHG-----AETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVA 211
++ + G A L S G Q+L G F R A+
Sbjct: 1311 QILIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALL 1370
Query: 212 LDDLEFWDCGLPTPQAN--------------CPP-GHHHCQNKVCVEPQQLCDGEDNCGD 256
G P + N CP C++K C+ LCD + +C D
Sbjct: 1371 K--------GPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSD 1422
Query: 257 LSDENPLTCGRHIAT----DFETGLGPWNRS----------EGWSRNHRAGGPERPSWPR 302
SDE C + +T +FET G W + W+ R P + P
Sbjct: 1423 RSDE--AHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRI--PAKALIPD 1478
Query: 303 RDHSRNSAQGSFLVSVA---EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEA-GCLQL 358
DH+ S Q V+ + E I +S F AS C++ F+ Y+ + G L++
Sbjct: 1479 SDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPAS-LGMCTVRFWFYMIDPRSMGILKV 1537
Query: 359 F-LQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILL-AGQTGPGGV-VGLD 415
+ ++ G +L+ G T W V + S PF++ A G + + LD
Sbjct: 1538 YTIEESG-----LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALD 1592
Query: 416 DLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC--GDLCVPPEQ 473
D+ + C + GP P P C+ +C CVP
Sbjct: 1593 DISFTPEC-----------VTGGPVPVQPSP----------CEADQFSCIYTLQCVPLSG 1631
Query: 474 LCDFEEQCAGGEDEQAC 490
CD E C G DE C
Sbjct: 1632 KCDGHEDCIDGSDEMDC 1648
Score = 57.8 bits (138), Expect = 6e-08
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 13/147 (8%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC-LTFWYHG-SLRSPG 822
P +DHT + Q H++ V++S G A +T+ + P + C + FW++ RS G
Sbjct: 1477 PDSDHTPGSGQ-HFLYVNSSGSK--EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMG 1533
Query: 823 TLRVYLEERGRHQVLSLSAHGG--LAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDD 880
L+VY E +L S G W GS+ + + ++V FEA G ++ALDD
Sbjct: 1534 ILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDD 1593
Query: 881 L-----LLQDGPCP-QPGSCDFESGLC 901
+ + GP P QP C+ + C
Sbjct: 1594 ISFTPECVTGGPVPVQPSPCEADQFSC 1620
Score = 53.5 bits (127), Expect = 1e-06
Identities = 55/213 (25%), Positives = 85/213 (39%), Gaps = 34/213 (15%)
Query: 556 SGPSCELHLAYYLQSQPREVSCNFERDT------CSWYPGHLSDTHWRW-----VESRGP 604
S S E H A+Y + SCNFE + CS D W ++ P
Sbjct: 1421 SDRSDEAHCAHYTSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIP 1477
Query: 605 DHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTEC-LSFWYHLHGPQ-IGTLRL 662
D DHT G G L + G A + + PA+ C + FW+++ P+ +G L++
Sbjct: 1478 DSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKV 1537
Query: 663 -AMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGT-MALDD 720
+ G +WS G + W LS S++ +++ FE DG +ALDD
Sbjct: 1538 YTIEESGLNILVWSVIGNKRTGWTYGSVPLS----SNSPFKVAFEADLDGNEDIFIALDD 1593
Query: 721 VA------------VRPGPCWAPNYCSFEDSDC 741
++ V+P PC A + C
Sbjct: 1594 ISFTPECVTGGPVPVQPSPCEADQFSCIYTLQC 1626
>gi|239744011 PREDICTED: chromosome 10 open reading frame 112 [Homo
sapiens]
Length = 1817
Score = 193 bits (491), Expect = 7e-49
Identities = 147/545 (26%), Positives = 231/545 (42%), Gaps = 69/545 (12%)
Query: 66 CDFEQDPCGWRD-ISTSGYSWLRD---RAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGK 121
CDFE + C W + IS + W+R A E P DH+L G +M +
Sbjct: 294 CDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSS 353
Query: 122 EASTAALRSPTLREAASSCKLRLWYH--AASGDVAELRVELTHGAETLTLWQSTGPWGPG 179
A L+SPT + C L W++ S AEL++ + + ++ +W+ G
Sbjct: 354 LWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQ 413
Query: 180 WQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPP-GHHHCQN 238
W E + GR+ F ++ + G A+DD+ F +C LP P +C H C++
Sbjct: 414 WLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRH 473
Query: 239 -KVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSE----GWSRNHRAG 293
+ C+E +LCD D+CGD +DE + C + +FETG+ W + W+R+ +
Sbjct: 474 TRACIEKLRLCDLVDDCGDRTDE--VNCAPELQCNFETGICNWEQDAKDDFDWTRS-QGP 530
Query: 294 GPERPSWPRRDHSRNSAQGSFL-VSVAEPGT---PAILSSPEFQASGTSNCSLVFYQYLS 349
P + P +D++ +A+G +L + +EP A L SP A+ T C+ FY ++
Sbjct: 531 TPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMF 590
Query: 350 GSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG 409
G L ++ + + LL + G G W+R ++I S PFQIL+ G G
Sbjct: 591 GKRIYRLAIYQRIWSDSRGQ---LLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDG 647
Query: 410 --GVVGLDDLILSDHCRPVSEVSTLQP------LPPGPRAPAPQPLPPSSRLQDSCKQGH 461
G + +DDL D TL P LP P P LPP +C
Sbjct: 648 FTGDIAIDDLSFMD--------CTLYPGNLPADLPTPPETSVPVTLPP-----HNCTDNE 694
Query: 462 LAC--GDLCVPPEQLCDFEEQCAGGEDEQAC--GTTDFESPEAGGW---------EDASV 508
C C+ Q CDF+ C DE +C FE W +D++
Sbjct: 695 FICRSDGHCIEKMQKCDFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPVHLLQDSNT 754
Query: 509 GRLQW---RRVSAQESQGSSAAAAGHFLSLQRAW--------GQLGAEARVLTPLLGPSG 557
R W +S + + + H + W G+ G A +LTP++ +G
Sbjct: 755 FR--WGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG 812
Query: 558 PSCEL 562
P C L
Sbjct: 813 PKCTL 817
Score = 191 bits (484), Expect = 4e-48
Identities = 178/675 (26%), Positives = 270/675 (40%), Gaps = 91/675 (13%)
Query: 28 CRSPGQAV-----CNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDP-CGW------ 75
CRS G + C+F DC D SDEA C C FE+ C W
Sbjct: 697 CRSDGHCIEKMQKCDFKYDCPDKSDEASCVME----------VCSFEKRSLCKWYQPIPV 746
Query: 76 ---RDISTSGYSWLRDRAGAALEGPGPHS---DHTLGTDLGWYMAVGTHRGKEASTAALR 129
+D +T + W + G H DHT T GWY+ + GK TA +
Sbjct: 747 HLLQDSNT--FRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLYADSSNGKFGDTADIL 804
Query: 130 SPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGR 189
+P + C L W H V L+V + T LW TG G W+ V G
Sbjct: 805 TPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLG- 863
Query: 190 IRGDFRVTFSATRNATHRGAVALDDLEFWDCG-LPTPQANCPPGHHHCQNKVCVEPQQLC 248
IR ++ F A R ++ G VA+DD+ F DC L +P+ C C NK C+ +LC
Sbjct: 864 IRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKCTDHEFMCANKHCIAKDKLC 923
Query: 249 DGEDNCGDLSDENPLTC----GRHIATDFETGLGPW--NRSEGWSRNHRAGG-PERPSWP 301
D ++C D SDE C GR DFE L W + E + N +A P + P
Sbjct: 924 DFVNDCADNSDETTFICRTSSGR---CDFEFDLCSWKQEKDEDFDWNLKASSIPAAGTEP 980
Query: 302 RRDHSRNSAQGSFL----VSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQ 357
DH+ ++ G ++ + +P A +SSP + + NC ++F+ ++ G+ G L
Sbjct: 981 AADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVI-SKRSKNCKIIFHYHMYGNGIGALT 1039
Query: 358 LFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG--GVVGLD 415
L ++ + VLL E G W R+ + + FQ+ G+ G G G + LD
Sbjct: 1040 LMQVSV---TNQTKVLL-NLTVEQGNFWRREELSLFGDEDFQLKFEGRVGKGQRGDIALD 1095
Query: 416 DLILSDHCRPVS---EVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC-GDLCVPP 471
D++L+++C + + PLP G C G+ C C
Sbjct: 1096 DIVLTENCLSLHDSVQEELAVPLPTG-----------------FCPLGYRECHNGKCYRL 1138
Query: 472 EQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGH 531
EQ C+F + C DE CG++ GW+++ W V S S H
Sbjct: 1139 EQSCNFVDNCGDNTDENECGSSCTFEKGWCGWQNSQADNFDW--VLGVGSHQSLRPPKDH 1196
Query: 532 FLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPREVSCNFERDTCSWYPGHL 591
L + A + R P+ S LH ++ +C+ + L
Sbjct: 1197 TLGNENA---ILLMRRHKYPI-----RSVNLHTVKHVLKAQTVGNCSVSK-----LEARL 1243
Query: 592 SDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYH 651
D E+ DHT HF+ L+ T G AH S ++ +SFWY
Sbjct: 1244 LDFLSVPNENTFGSSDHT--NWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYF 1301
Query: 652 LHGPQIGTLRLAMRR 666
+ G++++ ++R
Sbjct: 1302 VSAKATGSIQILIKR 1316
Score = 140 bits (354), Expect = 5e-33
Identities = 149/605 (24%), Positives = 235/605 (38%), Gaps = 128/605 (21%)
Query: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAAL 94
+C+ V DC D +DE C +P L C+FE C W + + W R +
Sbjct: 483 LCDLVDDCGDRTDEVNC-----APEL----QCNFETGICNWEQDAKDDFDWTRSQGPTPT 533
Query: 95 EGPGPHSDHTLGTDLGWYMAVGTHRGKE-ASTAALRSPTLREA-ASSCKLRLWYHAASGD 152
GP D+TLGT G Y+ + + + +AAL SP L C R +YH
Sbjct: 534 LNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKR 593
Query: 153 VAELRV--ELTHGAETLTLWQSTGPWGPGW--QELAVTTGRIRGDFRVTFSATRNATHRG 208
+ L + + + LWQ G G W + L +++ R F++ A+ G
Sbjct: 594 IYRLAIYQRIWSDSRGQLLWQIFGNQGNRWIRKHLNISS---RQPFQILVEASVGDGFTG 650
Query: 209 AVALDDLEFWDC---------GLPTPQA----------NCPPGHHHCQNK-VCVEPQQLC 248
+A+DDL F DC LPTP NC C++ C+E Q C
Sbjct: 651 DIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKC 710
Query: 249 DGEDNCGDLSDE-------------------NPLTCGRHIATD---FETGLGPWNRSEGW 286
D + +C D SDE P+ H+ D F GLG
Sbjct: 711 DFKYDCPDKSDEASCVMEVCSFEKRSLCKWYQPIPV--HLLQDSNTFRWGLGNGISIHHG 768
Query: 287 SRNHRAGGPERPSWPRRDHSRNSAQGSFLV---SVAEPGTPAILSSPEFQASGTSNCSLV 343
NHR P DH++N+ G +L S + G A + +P +G C+LV
Sbjct: 769 EENHR---------PSVDHTQNTTDGWYLYADSSNGKFGDTADILTPIISLTG-PKCTLV 818
Query: 344 FYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLA 403
F+ +++G+ G LQ+ ++ L + G+ G W R V + QI+
Sbjct: 819 FWTHMNGATVGSLQVLIK-----KDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFR 873
Query: 404 GQTGPG--GVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQD---SCK 458
+ G G V +DD+ D C P+ L P + D C
Sbjct: 874 AKRGISYIGDVAVDDISFQD-CSPL--------------------LSPERKCTDHEFMCA 912
Query: 459 QGHLACGDLCVPPEQLCDFEEQCAGGEDE------QACGTTDFESPEAGGWEDASVGRLQ 512
H C+ ++LCDF CA DE + G DFE + W+
Sbjct: 913 NKH------CIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF-DLCSWKQEKDEDFD 965
Query: 513 WR-RVSAQESQGSSAAA-------AGHFLSLQRAWGQLGAE-ARVLTPLLGPSGPSCELH 563
W + S+ + G+ AA +GH++ ++ + Q AR+ +P++ +C++
Sbjct: 966 WNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAARISSPVISKRSKNCKII 1025
Query: 564 LAYYL 568
Y++
Sbjct: 1026 FHYHM 1030
Score = 135 bits (339), Expect = 3e-31
Identities = 142/591 (24%), Positives = 238/591 (40%), Gaps = 105/591 (17%)
Query: 573 REVSCNFERDTCSWYPGHLSDTHWRWV------ESRGPDHDHTTGQGH--FVLLDPT-DP 623
+ ++C+FE C W P D+HW+ + E P DHT H F+ L+ P
Sbjct: 112 KHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLEAQRSP 171
Query: 624 LAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQG-- 681
+ +L++ + P + + FWYHL Q L + R T L QG
Sbjct: 172 GVAKLGSPVLTKLLTASTPCQ-VQFWYHLS--QHSNLSVFTR-----TSLDGNLQKQGKI 223
Query: 682 -----NRWHEAWATLSHQPG-SHAQYQLLFEGLRDGYHGTMALDDVAV------------ 723
++W A L + G S +QL+ E + T+ALDD++V
Sbjct: 224 IRFSESQWSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDISVSQECEISYKSLP 283
Query: 724 RPGPCWAPNYCSFEDSDCGFSPGGQGL---WRRQANASGHAAW---GPPTDHTTETAQGH 777
R + C FE + C + G W R + + A + PP DH+ +QGH
Sbjct: 284 RTSTQSKFSKCDFEANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGH 343
Query: 778 YMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQ-- 835
+M + +L Q A L S L+FW++ S G + L H
Sbjct: 344 FMFILKKSSSL--WQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMENSHDST 401
Query: 836 -VLSLSAHGGLAWRLGSMDV-QAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGS 893
+ + + G W ++ + + + + + + V+ G+ A+DD+ ++ P P
Sbjct: 402 VIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYDGVSAIDDIRFENCTLPLPAE 461
Query: 894 -------------------------------------------CDFESGLCGWSHLAWPG 910
C+FE+G+C W A
Sbjct: 462 SCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDA--- 518
Query: 911 LGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPA 970
+ W G TP+ P D+TLGT GH+ + E+ +A L S L AT
Sbjct: 519 KDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQAFQDSAALLSPILNATDT 578
Query: 971 S--CLRFWYHMGFPEHFYKGELKVLLHS-AQGQLAVWGAGGHRRHQWLEAQVEVASAKEF 1027
RF+YHM F + Y+ + + S ++GQL +W G++ ++W+ + ++S + F
Sbjct: 579 KGCTFRFYYHM-FGKRIYRLAIYQRIWSDSRGQL-LWQIFGNQGNRWIRKHLNISSRQPF 636
Query: 1028 QIVFEATLGGQPALGPIALDDVEY----LAGQHCQQPAPSPGNTAAPGSVP 1074
QI+ EA++ G G IA+DD+ + L + P+P T+ P ++P
Sbjct: 637 QILVEASV-GDGFTGDIAIDDLSFMDCTLYPGNLPADLPTPPETSVPVTLP 686
Score = 103 bits (256), Expect = 1e-21
Identities = 154/667 (23%), Positives = 235/667 (35%), Gaps = 159/667 (23%)
Query: 541 QLGAEARVL----TPLLGPSGPSCELHLAYY----LQSQPREVSCNFERDTCSWYPGHLS 592
QL EA VL T L S E ++Y +Q + C+FE ++C W+ +S
Sbjct: 250 QLILEATVLSSNATVALDDISVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFEA-IS 308
Query: 593 DTHWRWV-----------ESRGPDHDHT--TGQGHFVLLDPTDPLAWGHSAHLLSRPQVP 639
H+ W+ E + P DH+ QGHF+ + W A L S
Sbjct: 309 GDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILKKSSSLW-QVAKLQSPTFSQ 367
Query: 640 AAPTECLSFWYHLHGPQIGT--LRLAMRREGEETHLWSRSGTQGNRWHEAWATLSH--QP 695
P LSFW++ +G +G L+L M + T +W QG +W EA L QP
Sbjct: 368 TGPGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQP 427
Query: 696 GSHAQYQLLFEGLRDGYHGTMALDDV----AVRPGP------------------------ 727
H + G+ Y G A+DD+ P P
Sbjct: 428 -FHLSLDKVSLGI---YDGVSAIDDIRFENCTLPLPAESCEGLDHFWCRHTRACIEKLRL 483
Query: 728 ---------------CWAPNYCSFEDSDCGFSPGGQG--LWRRQANASGHAAWGPPTDHT 770
C C+FE C + + W R + GP D+T
Sbjct: 484 CDLVDDCGDRTDEVNCAPELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNT 543
Query: 771 TETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVY--L 828
TA+GHY+ +++S + A L+ + + F+YH + L +Y +
Sbjct: 544 LGTAKGHYLYIESSEPQAFQDSAALLSPILNATDTKGCTFRFYYHMFGKRIYRLAIYQRI 603
Query: 829 EERGRHQVL-SLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDL------ 881
R Q+L + + G W +++ + + ++++ EA +A+DDL
Sbjct: 604 WSDSRGQLLWQIFGNQGNRWIRKHLNISSRQPFQILVEASVGDGFTGDIAIDDLSFMDCT 663
Query: 882 -----LLQDGPCPQPGS-----------------------------CDF----------- 896
L D P P S CDF
Sbjct: 664 LYPGNLPADLPTPPETSVPVTLPPHNCTDNEFICRSDGHCIEKMQKCDFKYDCPDKSDEA 723
Query: 897 ----------ESGLCGW-----SHLAWPGLGGYSWDWGGGAT---PSRYPQPPVDHTLGT 938
+ LC W HL + W G G + +P VDHT T
Sbjct: 724 SCVMEVCSFEKRSLCKWYQPIPVHLLQDS-NTFRWGLGNGISIHHGEENHRPSVDHTQNT 782
Query: 939 EAGHFAFFETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSA 997
G + + ++ G G A + + + T C L FW HM G L+VL+
Sbjct: 783 TDGWYLYADSS-NGKFGDTADILTPIISLTGPKCTLVFWTHMNGAT---VGSLQVLIKKD 838
Query: 998 QGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHC 1057
+W G + QW A+V + QIVF A G +G +A+DD+ + Q C
Sbjct: 839 NVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAK-RGISYIGDVAVDDISF---QDC 894
Query: 1058 QQPAPSP 1064
P SP
Sbjct: 895 -SPLLSP 900
Score = 95.9 bits (237), Expect = 2e-19
Identities = 105/429 (24%), Positives = 166/429 (38%), Gaps = 76/429 (17%)
Query: 194 FRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDN 253
F++ F T + R +ALD L + CG + C C + C+ + +CD +
Sbjct: 40 FKIIFEGTL-LSQRSFIALDHLWVYACGQTQSRKLCSADEFPCTSGQCIAKESVCDSRQD 98
Query: 254 CGDLSDENPLTCGRHIATDFETGLGPW----NRSEGWSRNHRAGGPERPSWPRRDHSRNS 309
C D SDE+P TC +H+ DFE+G W W E +P DH+ N
Sbjct: 99 CSDESDEDPATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEH-HFPAADHTANI 157
Query: 310 AQGSFLVSVAE--PGTPAILSSPEFQ--ASGTSNCSLVFYQYLSGSEAGCLQLFLQT-LG 364
GSF+ A+ PG A L SP + ++ C + F+ +L S+ L +F +T L
Sbjct: 158 NHGSFIYLEAQRSPGV-AKLGSPVLTKLLTASTPCQVQFWYHL--SQHSNLSVFTRTSLD 214
Query: 365 PGAPRAPVLLRRRRGELGTAWVRDRVDI-----QSAYPFQILL-AGQTGPGGVVGLDDLI 418
+ ++R + W ++D+ +S PFQ++L A V LDD+
Sbjct: 215 GNLQKQGKIIRFSESQ----WSHAKIDLIAEAGESTLPFQLILEATVLSSNATVALDDIS 270
Query: 419 LSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFE 478
+S C E+S + LP +S K CDFE
Sbjct: 271 VSQEC----EISY-------------KSLPRTSTQSKFSK----------------CDFE 297
Query: 479 EQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWR-RVSAQESQGSSAAAAGHFLSLQR 537
+C + S + W +S L A S A+ GHF+ + +
Sbjct: 298 --------ANSCDWFEAISGDHFDWIRSSQSELSADFEHQAPPRDHSLNASQGHFMFILK 349
Query: 538 AWGQLGAEARVLTPLLGPSGPSCELHLAYY---LQSQPREVSCNFERDTCSWYPGHLSDT 594
L A++ +P +GP C L +Y L E+ + E H S
Sbjct: 350 KSSSLWQVAKLQSPTFSQTGPGCILSFWFYNYGLSVGAAELQLHMEN-------SHDSTV 402
Query: 595 HWRWVESRG 603
WR + ++G
Sbjct: 403 IWRVLYNQG 411
Score = 91.3 bits (225), Expect = 5e-18
Identities = 109/483 (22%), Positives = 178/483 (36%), Gaps = 131/483 (27%)
Query: 577 CNFE-RDTCSWY---PGHL--SDTHWRW-----------VESRGPDHDHT--TGQGHFVL 617
C+FE R C WY P HL +RW E+ P DHT T G ++
Sbjct: 730 CSFEKRSLCKWYQPIPVHLLQDSNTFRWGLGNGISIHHGEENHRPSVDHTQNTTDGWYLY 789
Query: 618 LDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRS 677
D ++ +G +A +L+ P L FW H++G +G+L++ ++++ + LW+++
Sbjct: 790 ADSSNG-KFGDTADILTPIISLTGPKCTLVFWTHMNGATVGSLQVLIKKDNVTSKLWAQT 848
Query: 678 GTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRD-GYHGTMALDDVAVRP-GPCWAP---- 731
G QG +W A L G + Q++F R Y G +A+DD++ + P +P
Sbjct: 849 GQQGAQWKRAEVFL----GIRSHTQIVFRAKRGISYIGDVAVDDISFQDCSPLLSPERKC 904
Query: 732 ---------NYCSFEDSDCGF-----------------SPGGQGL--------------- 750
+C +D C F S G
Sbjct: 905 TDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEFDLCSWKQEKDEDF 964
Query: 751 -WRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC 809
W +A++ A P DHT + GHY+ + + P + A ++S ++
Sbjct: 965 DWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPM-RAARISSPVISKRSKNCK 1023
Query: 810 LTFWYH--GSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAV 867
+ F YH G+ TL +L+L+ G WR + + + +++ FE
Sbjct: 1024 IIFHYHMYGNGIGALTLMQVSVTNQTKVLLNLTVEQGNFWRREELSLFGDEDFQLKFEGR 1083
Query: 868 AAGVAHSYVALDDLLLQD-------------------GPCPQ------------------ 890
+ALDD++L + G CP
Sbjct: 1084 VGKGQRGDIALDDIVLTENCLSLHDSVQEELAVPLPTGFCPLGYRECHNGKCYRLEQSCN 1143
Query: 891 --------------PGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTL 936
SC FE G CGW + ++DW G + +PP DHTL
Sbjct: 1144 FVDNCGDNTDENECGSSCTFEKGWCGWQNSQ-----ADNFDWVLGVGSHQSLRPPKDHTL 1198
Query: 937 GTE 939
G E
Sbjct: 1199 GNE 1201
Score = 80.9 bits (198), Expect = 6e-15
Identities = 136/569 (23%), Positives = 210/569 (36%), Gaps = 102/569 (17%)
Query: 33 QAVCNFVCDCRDCSDE--AQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRA 90
++VC+ DC D SDE A C H CDFE CGW T W +
Sbjct: 90 ESVCDSRQDCSDESDEDPATCSKH---------LTCDFESGFCGWEPFLTEDSHWKLMKG 140
Query: 91 GAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLRE---AASSCKLRLWYH 147
E P +DHT + G ++ + R A L SP L + A++ C+++ WYH
Sbjct: 141 LNNGEHHFPAADHTANINHGSFIYLEAQR--SPGVAKLGSPVLTKLLTASTPCQVQFWYH 198
Query: 148 AASGDVAEL--RVELTHGAET--LTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRN 203
+ + R L + + S W +L G F++ AT
Sbjct: 199 LSQHSNLSVFTRTSLDGNLQKQGKIIRFSESQWSHAKIDLIAEAGESTLPFQLILEATVL 258
Query: 204 ATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPL 263
+++ VALDD+ + C + CD E N D +
Sbjct: 259 SSN-ATVALDDI--------SVSQECEISYKSLPRTSTQSKFSKCDFEANSCDWFE---A 306
Query: 264 TCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGT 323
G H W RS S++ + E + P RDHS N++QG F+ + + +
Sbjct: 307 ISGDHF---------DWIRS---SQSELSADFEHQA-PPRDHSLNASQGHFMFILKKSSS 353
Query: 324 ---PAILSSPEFQASGTSNCSLVFYQYLSGSEAGC--LQLFLQTLGPGAPRAPVLLRRRR 378
A L SP F +G C L F+ Y G G LQL ++ VL +
Sbjct: 354 LWQVAKLQSPTFSQTG-PGCILSFWFYNYGLSVGAAELQLHMENSHDSTVIWRVLYNQ-- 410
Query: 379 GELGTAWVRDRVDI-QSAYPFQILLAGQTGPG---GVVGLDDLILSDHCRPVSEVSTLQP 434
G W+ + + + + PF + L + G GV +DD I ++C TL P
Sbjct: 411 ---GKQWLEATIQLGRLSQPFHLSL-DKVSLGIYDGVSAIDD-IRFENC-------TL-P 457
Query: 435 LPPGPRAPAPQPLPPSSRLQDSCK-QGHLACGD--LCVPPEQLCDFEEQCAGGEDEQACG 491
LP +SC+ H C C+ +LCD + C DE C
Sbjct: 458 LP-----------------AESCEGLDHFWCRHTRACIEKLRLCDLVDDCGDRTDEVNCA 500
Query: 492 TTDFESPEAG--GWEDASVGRLQWRRV--------SAQESQGSSAAAAGHFLSLQRAWGQ 541
+ E G WE + W R + + A GH+L ++ + Q
Sbjct: 501 PELQCNFETGICNWEQDAKDDFDWTRSQGPTPTLNTGPMKDNTLGTAKGHYLYIESSEPQ 560
Query: 542 LGAE-ARVLTPLLGPSG-PSCELHLAYYL 568
+ A +L+P+L + C Y++
Sbjct: 561 AFQDSAALLSPILNATDTKGCTFRFYYHM 589
Score = 75.9 bits (185), Expect = 2e-13
Identities = 86/384 (22%), Positives = 150/384 (39%), Gaps = 75/384 (19%)
Query: 725 PGPCWAPNYCSFEDSDCGFSP--GGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVD 782
P C C FE CG+ P W+ + P DHT G ++ ++
Sbjct: 107 PATCSKHLTCDFESGFCGWEPFLTEDSHWKLMKGLNNGEHHFPAADHTANINHGSFIYLE 166
Query: 783 T--SPDALPRGQ---TASLTSKEHRPLAQPACLTFWYH----------------GSLRSP 821
SP G T LT+ + P + FWYH G+L+
Sbjct: 167 AQRSPGVAKLGSPVLTKLLTA------STPCQVQFWYHLSQHSNLSVFTRTSLDGNLQKQ 220
Query: 822 GTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDL 881
G + + E + H + L A G ++ ++++ EA +++ VALDD+
Sbjct: 221 GKIIRFSESQWSHAKIDLIAEAG----------ESTLPFQLILEATVLS-SNATVALDDI 269
Query: 882 ------------LLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPS---- 925
L + + CDFE+ C W + + G +DW +
Sbjct: 270 SVSQECEISYKSLPRTSTQSKFSKCDFEANSCDW----FEAISGDHFDWIRSSQSELSAD 325
Query: 926 -RYPQPPVDHTLGTEAGHFAFF--ETGVLGPGGRAAWLRSEPLPATPASC-LRFWYHMGF 981
+ PP DH+L GHF F ++ L + A L+S T C L FW++ +
Sbjct: 326 FEHQAPPRDHSLNASQGHFMFILKKSSSLW---QVAKLQSPTFSQTGPGCILSFWFY-NY 381
Query: 982 PEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVAS-AKEFQIVFE-ATLGGQP 1039
EL++ + ++ +W ++ QWLEA +++ ++ F + + +LG
Sbjct: 382 GLSVGAAELQLHMENSHDSTVIWRVLYNQGKQWLEATIQLGRLSQPFHLSLDKVSLGIYD 441
Query: 1040 ALGPIALDDVEYLAGQHCQQPAPS 1063
G A+DD+ + ++C P P+
Sbjct: 442 --GVSAIDDIRF---ENCTLPLPA 460
Score = 73.9 bits (180), Expect = 8e-13
Identities = 78/336 (23%), Positives = 126/336 (37%), Gaps = 63/336 (18%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
P DHT T G Y+ D+S G TA + + L FW H + + G+L
Sbjct: 774 PSVDHTQNTTDGWYLYADSSNGKF--GDTADILTPIISLTGPKCTLVFWTHMNGATVGSL 831
Query: 825 RVYLEERG-RHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLL 883
+V +++ ++ + + G W+ + + ++VF A VA+DD+
Sbjct: 832 QVLIKKDNVTSKLWAQTGQQGAQWKRAEVFLGIRSHTQIVFRAKRGISYIGDVAVDDISF 891
Query: 884 QD-GPCPQP--------------------------------------------GSCDFES 898
QD P P G CDFE
Sbjct: 892 QDCSPLLSPERKCTDHEFMCANKHCIAKDKLCDFVNDCADNSDETTFICRTSSGRCDFEF 951
Query: 899 GLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAA 958
LC W + W+ + P+ +P DHTLG +GH+ F ++ RAA
Sbjct: 952 DLCSWKQEKDED---FDWNLKASSIPAAGTEPAADHTLGNSSGHYIFIKSLFPQQPMRAA 1008
Query: 959 WLRSEPLPATPASC-LRFWYHM---GFPEHFYKGELKVLLHSAQGQLAV-WGAGGHRRHQ 1013
+ S + +C + F YHM G G L ++ S Q V + +
Sbjct: 1009 RISSPVISKRSKNCKIIFHYHMYGNGI------GALTLMQVSVTNQTKVLLNLTVEQGNF 1062
Query: 1014 WLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDV 1049
W ++ + ++FQ+ FE + G+ G IALDD+
Sbjct: 1063 WRREELSLFGDEDFQLKFEGRV-GKGQRGDIALDDI 1097
Score = 65.5 bits (158), Expect = 3e-10
Identities = 54/177 (30%), Positives = 77/177 (43%), Gaps = 10/177 (5%)
Query: 892 GSCDFESGLCGWSHLAWPGLGGYS-WDWG-GGATPSRYPQPPVDHTLGTEAGHFAFFETG 949
GSC+FE+ W+ DW G P++ P DHT G+ HF + +
Sbjct: 1437 GSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIPDSDHTPGS-GQHFLYVNSS 1495
Query: 950 VLGPGGRAAWLRSEPLPATPASC-LRFWYHMGFPEHFYKGELKVLLHSAQG-QLAVWGAG 1007
G A S+ PA+ C +RFW++M P G LKV G + VW
Sbjct: 1496 GSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSM--GILKVYTIEESGLNILVWSVI 1553
Query: 1008 GHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSP 1064
G++R W V ++S F++ FEA L G + IALDD+ + C P P
Sbjct: 1554 GNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIF-IALDDISFT--PECVTGGPVP 1607
Score = 64.3 bits (155), Expect = 6e-10
Identities = 62/240 (25%), Positives = 99/240 (41%), Gaps = 21/240 (8%)
Query: 35 VCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWR---DISTSGYSWLRDRAG 91
+C++ DC D SDEA C ++ + T G +C+FE W ++ L G
Sbjct: 1413 LCDYKPDCSDRSDEAHCAHY--TSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIG 1467
Query: 92 AALEGPG--PHSDHTLGTDLGWYMAVGTHRGKEASTAAL-RSPTLREAASSCKLRLWYHA 148
+ + P SDHT G+ ++ V + KE S A + S + + C +R W++
Sbjct: 1468 SRIPAKALIPDSDHTPGSG-QHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYM 1526
Query: 149 AS-GDVAELRV-ELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATH 206
+ L+V + + +W G GW +V F+V F A +
Sbjct: 1527 IDPRSMGILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSS-NSPFKVAFEADLDGNE 1585
Query: 207 RGAVALDDLEFW-DC----GLPTPQANCPPGHHHC-QNKVCVEPQQLCDGEDNCGDLSDE 260
+ALDD+ F +C +P + C C CV CDG ++C D SDE
Sbjct: 1586 DIFIALDDISFTPECVTGGPVPVQPSPCEADQFSCIYTLQCVPLSGKCDGHEDCIDGSDE 1645
Score = 62.8 bits (151), Expect = 2e-09
Identities = 101/435 (23%), Positives = 153/435 (35%), Gaps = 89/435 (20%)
Query: 101 SDHTLGTDLGWYMAV--GTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRV 158
SDHT W+ T G A RS RE++++C + WY ++ +++
Sbjct: 1258 SDHT-----NWHFMYLEATAVGLRGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQI 1312
Query: 159 ELTHG-----AETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALD 213
+ G A L S G Q+L G F R A+
Sbjct: 1313 LIKRGRRRRRAPNPVLSGSPTIPRQGSQQLGGWRGGSARHRARAFPEPECPRGRSALLK- 1371
Query: 214 DLEFWDCGLPTPQAN--------------CPP-GHHHCQNKVCVEPQQLCDGEDNCGDLS 258
G P + N CP C++K C+ LCD + +C D S
Sbjct: 1372 -------GPPQEKPNRRSALLSVGEISELCPEITDFLCRDKKCIASHLLCDYKPDCSDRS 1424
Query: 259 DENPLTCGRHIAT----DFETGLGPWNRS----------EGWSRNHRAGGPERPSWPRRD 304
DE C + +T +FET G W + W+ R P + P D
Sbjct: 1425 DE--AHCAHYTSTTGSCNFETSSGNWTTACSLTQDSEDDLDWAIGSRI--PAKALIPDSD 1480
Query: 305 HSRNSAQGSFLVSVA---EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEA-GCLQLF- 359
H+ S Q V+ + E I +S F AS C++ F+ Y+ + G L+++
Sbjct: 1481 HTPGSGQHFLYVNSSGSKEGSVARITTSKSFPAS-LGMCTVRFWFYMIDPRSMGILKVYT 1539
Query: 360 LQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILL-AGQTGPGGV-VGLDDL 417
++ G +L+ G T W V + S PF++ A G + + LDD+
Sbjct: 1540 IEESG-----LNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDDI 1594
Query: 418 ILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLAC--GDLCVPPEQLC 475
+ C + GP P P C+ +C CVP C
Sbjct: 1595 SFTPEC-----------VTGGPVPVQPSP----------CEADQFSCIYTLQCVPLSGKC 1633
Query: 476 DFEEQCAGGEDEQAC 490
D E C G DE C
Sbjct: 1634 DGHEDCIDGSDEMDC 1648
Score = 57.8 bits (138), Expect = 6e-08
Identities = 44/147 (29%), Positives = 70/147 (47%), Gaps = 13/147 (8%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPAC-LTFWYHG-SLRSPG 822
P +DHT + Q H++ V++S G A +T+ + P + C + FW++ RS G
Sbjct: 1477 PDSDHTPGSGQ-HFLYVNSSGSK--EGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMG 1533
Query: 823 TLRVYLEERGRHQVLSLSAHGG--LAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDD 880
L+VY E +L S G W GS+ + + ++V FEA G ++ALDD
Sbjct: 1534 ILKVYTIEESGLNILVWSVIGNKRTGWTYGSVPLSSNSPFKVAFEADLDGNEDIFIALDD 1593
Query: 881 L-----LLQDGPCP-QPGSCDFESGLC 901
+ + GP P QP C+ + C
Sbjct: 1594 ISFTPECVTGGPVPVQPSPCEADQFSC 1620
Score = 53.5 bits (127), Expect = 1e-06
Identities = 55/213 (25%), Positives = 85/213 (39%), Gaps = 34/213 (15%)
Query: 556 SGPSCELHLAYYLQSQPREVSCNFERDT------CSWYPGHLSDTHWRW-----VESRGP 604
S S E H A+Y + SCNFE + CS D W ++ P
Sbjct: 1421 SDRSDEAHCAHYTSTTG---SCNFETSSGNWTTACSLTQDSEDDLDWAIGSRIPAKALIP 1477
Query: 605 DHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTEC-LSFWYHLHGPQ-IGTLRL 662
D DHT G G L + G A + + PA+ C + FW+++ P+ +G L++
Sbjct: 1478 DSDHTPGSGQHFLYVNSSGSKEGSVARITTSKSFPASLGMCTVRFWFYMIDPRSMGILKV 1537
Query: 663 -AMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGT-MALDD 720
+ G +WS G + W LS S++ +++ FE DG +ALDD
Sbjct: 1538 YTIEESGLNILVWSVIGNKRTGWTYGSVPLS----SNSPFKVAFEADLDGNEDIFIALDD 1593
Query: 721 VA------------VRPGPCWAPNYCSFEDSDC 741
++ V+P PC A + C
Sbjct: 1594 ISFTPECVTGGPVPVQPSPCEADQFSCIYTLQC 1626
Score = 31.2 bits (69), Expect = 5.9
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
Query: 767 TDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRV 826
+DHT H+M ++ + L RG A S R + ++FWY S ++ G++++
Sbjct: 1258 SDHTN----WHFMYLEATAVGL-RGDKAHFRSTMWRESSAACTMSFWYFVSAKATGSIQI 1312
Query: 827 YLEERGRHQ 835
L +RGR +
Sbjct: 1313 -LIKRGRRR 1320
>gi|223278413 MAM domain containing 2 [Homo sapiens]
Length = 686
Score = 126 bits (317), Expect = 1e-28
Identities = 157/589 (26%), Positives = 236/589 (40%), Gaps = 69/589 (11%)
Query: 503 WEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWGQLGAEARVLTPLLGPSGPSCEL 562
+ED S RL W SA+E S A+ L LQ + + ++L + G + +
Sbjct: 106 FEDESFDRLLW---SAKEPSDSWLIAS---LDLQNS----SKKFKILIEGVLGQGNTASI 155
Query: 563 HLAYYLQSQPREVSCNFERD-TCSWYPGHLSDTHW-------RWVESRGP-DHDHTTGQG 613
L + + C+FE + C + + +W R V S P DH + G
Sbjct: 156 ALFEIKMTTGYCIECDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELG 215
Query: 614 HFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRR-EGEETH 672
H++ +D + A L+S P A CLSF+Y + L R G
Sbjct: 216 HYMYVDSVYVKHFQEVAQLIS-PLTTAPMAGCLSFYYQIQQGNDNVFSLYTRDVAGLYEE 274
Query: 673 LWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPN 732
+W W+ A S +++ F G + GY +ALDD++ P C
Sbjct: 275 IWKADRPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGY---VALDDISFSPVHCQNQT 331
Query: 733 Y---------CSFEDSDCGF--SPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVV 781
C+FE C F G G R + + + A DHTT G+Y++
Sbjct: 332 ELLFSAVEASCNFEQDLCNFYQDKEGPGWTRVKVKPNMYRAG----DHTT--GLGYYLLA 385
Query: 782 DTSPDALPRGQTASLTSKEHRPLAQPACLTFWY--HGSLRSPGTLRVYLEERG---RHQV 836
+T + P G L P CL F Y +G L+ TL VY+ E + ++
Sbjct: 386 NTKFTSQP-GYIGRLYGPS-LPGNLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKI 443
Query: 837 LSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAH-SYVALDDLLLQDGPC------- 888
S+ W + + +VVF ++ VALDD+ +Q G C
Sbjct: 444 WSVLESPRGVWMQAEITFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGSCSSSEKLP 503
Query: 889 PQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFET 948
P PG C FE C ++ SW G TP+ Y P DHT G G++ + E
Sbjct: 504 PPPGECTFEQDECTFTQ---EKRNRSSWHRRRGETPTSYTGPKGDHTTGV--GYYMYIEA 558
Query: 949 GVLGPGGRAAWLRSEPLPATPAS-CLRFWYHMGFPEHFYKGELKVLLHSAQG--QLAVWG 1005
+ G +A L S PL CL F+YHM G L V L + + +W
Sbjct: 559 SHMVYGQKARLL-SRPLRGVSGKHCLTFFYHMYGGG---TGLLSVYLKKEEDSEESLLWR 614
Query: 1006 AGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAG 1054
G + WL A +E + ++ QI+FEA + G IA+DDV++ AG
Sbjct: 615 RRGEQSISWLRALIEYSCERQHQIIFEA-IRGVSIRSDIAIDDVKFQAG 662
Score = 121 bits (304), Expect = 3e-27
Identities = 95/334 (28%), Positives = 152/334 (45%), Gaps = 27/334 (8%)
Query: 574 EVSCNFERDTCSWYPGHLSDTHWRWVESRGPDH---DHTTGQGHFVLLDPTDPLAWGHSA 630
E SCNFE+D C++Y W V+ + + DHTTG G+++L + G+
Sbjct: 339 EASCNFEQDLCNFYQDK-EGPGWTRVKVKPNMYRAGDHTTGLGYYLLANTKFTSQPGYIG 397
Query: 631 HLLSRPQVPAAPTECLSFWYHLHG--PQIGTLRLAMRREGE--ETHLWSRSGTQGNRWHE 686
L P +P CL F Y ++G TL + + E + +WS + W +
Sbjct: 398 RLYG-PSLPGNLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQ 456
Query: 687 AWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWA-------PNYCSFEDS 739
A T + + L + D G +ALDD+ ++ G C + P C+FE
Sbjct: 457 AEITFKKPMPTKVVFMSLCKSFWDC--GLVALDDITIQLGSCSSSEKLPPPPGECTFEQD 514
Query: 740 DCGFSPG--GQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLT 797
+C F+ + W R+ + + GP DHTT G+YM ++ S + GQ A L
Sbjct: 515 ECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGV--GYYMYIEASH--MVYGQKARLL 570
Query: 798 SKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLSAHGG---LAWRLGSMDV 854
S+ R ++ CLTF+YH G L VYL++ + L G ++W ++
Sbjct: 571 SRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEY 630
Query: 855 QAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPC 888
ER +++FEA+ S +A+DD+ Q GPC
Sbjct: 631 SCERQHQIIFEAIRGVSIRSDIAIDDVKFQAGPC 664
Score = 90.5 bits (223), Expect = 8e-18
Identities = 86/335 (25%), Positives = 147/335 (43%), Gaps = 42/335 (12%)
Query: 734 CSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQT 793
C+FE+S CGF + W +GHY+ VDTS +G+
Sbjct: 26 CAFEESTCGFD-----------SVLASLPW-------ILNEEGHYIYVDTSFGK--QGEK 65
Query: 794 ASLTSKEHRPLAQPACLTFWYH-----GSLRSPGTLRVYL--EERGRHQVLSLSAHGGLA 846
A L S + + + +CL Y SL P L +Y+ E+ ++L + +
Sbjct: 66 AVLLSPDLQA-EEWSCLRLVYQITTSSESLSDPSQLNLYMRFEDESFDRLLWSAKEPSDS 124
Query: 847 WRLGSMDVQ-AERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESG-LCGWS 904
W + S+D+Q + + ++++ E V + +AL ++ + G C + CDFE LCG+
Sbjct: 125 WLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTTGYCIE---CDFEENHLCGFV 181
Query: 905 HLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEP 964
+ P + +W GGG+ + + P DHT +E GH+ + ++ + A L S
Sbjct: 182 NRWNPNV---NWFVGGGSIRNVHSILPQDHTFKSELGHYMYVDSVYVKHFQEVAQLISPL 238
Query: 965 LPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQL-AVWGAGGHRRHQWLEAQVEVAS 1023
A A CL F+Y + + + G +W A W A+VE ++
Sbjct: 239 TTAPMAGCLSFYYQI---QQGNDNVFSLYTRDVAGLYEEIWKADRPGNAAWNLAEVEFSA 295
Query: 1024 AKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQ 1058
+++FE G P G +ALDD+ + + HCQ
Sbjct: 296 PYPMEVIFEVAFNG-PKGGYVALDDISF-SPVHCQ 328
Score = 89.4 bits (220), Expect = 2e-17
Identities = 53/166 (31%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 572 PREVSCNFERDTCSWYPGHLSDTHWRWVESR------GPDHDHTTGQGHFVLLDPTDPLA 625
P C FE+D C++ + + W GP DHTTG G+++ ++ + +
Sbjct: 504 PPPGECTFEQDECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGVGYYMYIEASH-MV 562
Query: 626 WGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRRE--GEETHLWSRSGTQGNR 683
+G A LLSRP + CL+F+YH++G G L + +++E EE+ LW R G Q
Sbjct: 563 YGQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSIS 622
Query: 684 WHEAWATLSHQPGSHAQYQLLFEGLRD-GYHGTMALDDVAVRPGPC 728
W A S Q+Q++FE +R +A+DDV + GPC
Sbjct: 623 WLRALIEYS----CERQHQIIFEAIRGVSIRSDIAIDDVKFQAGPC 664
Score = 63.9 bits (154), Expect = 8e-10
Identities = 46/157 (29%), Positives = 63/157 (40%), Gaps = 5/157 (3%)
Query: 63 PFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKE 122
P C FEQD C + + SW R R GP DHT G +G+YM +
Sbjct: 506 PGECTFEQDECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTG--VGYYMYIEASHMVY 563
Query: 123 ASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVEL--THGAETLTLWQSTGPWGPGW 180
A L S LR + L +YH G L V L +E LW+ G W
Sbjct: 564 GQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISW 623
Query: 181 QELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEF 217
+ R ++ F A R + R +A+DD++F
Sbjct: 624 LRALIEYSCER-QHQIIFEAIRGVSIRSDIAIDDVKF 659
Score = 44.3 bits (103), Expect = 7e-04
Identities = 81/352 (23%), Positives = 122/352 (34%), Gaps = 56/352 (15%)
Query: 65 ACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTH-RGKEA 123
+C+FEQD C + G W R + + G DHT G LG+Y+ T +
Sbjct: 341 SCNFEQDLCNFYQ-DKEGPGWTRVKVKPNMYRAG---DHTTG--LGYYLLANTKFTSQPG 394
Query: 124 STAALRSPTLREAASSCKLRLWYHAA-------SGDVAELRVELTHGAETLTLWQSTGPW 176
L P+L C L +H A S +A E H + P
Sbjct: 395 YIGRLYGPSLPGNLQYC---LRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPR 451
Query: 177 GPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHC 236
G W + +T + V S ++ G VALDD+ G + PP C
Sbjct: 452 GV-WMQAEITFKKPMPTKVVFMSLCKSFWDCGLVALDDITI-QLGSCSSSEKLPPPPGEC 509
Query: 237 QNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPE 296
+ +D C ++ NRS W R R P
Sbjct: 510 TFE-----------QDECTFTQEKR-------------------NRSS-WHRR-RGETPT 537
Query: 297 RPSWPRRDHSRNSAQGSFL-VSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGC 355
+ P+ DH+ ++ S G A L S + +C L F+ ++ G G
Sbjct: 538 SYTGPKGDHTTGVGYYMYIEASHMVYGQKARLLSRPLRGVSGKHC-LTFFYHMYGGGTGL 596
Query: 356 LQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTG 407
L ++L+ LL RRRGE +W+R ++ QI+ G
Sbjct: 597 LSVYLKKEEDSEES---LLWRRRGEQSISWLRALIEYSCERQHQIIFEAIRG 645
Score = 42.7 bits (99), Expect = 0.002
Identities = 84/381 (22%), Positives = 134/381 (35%), Gaps = 88/381 (23%)
Query: 65 ACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEAS 124
+C FE+ CG+ + S W+ + G Y+ V T GK+
Sbjct: 25 SCAFEESTCGFDSVLAS-LPWILNEEGH-------------------YIYVDTSFGKQGE 64
Query: 125 TAALRSPTLREAASSCKLRLWYHAAS-----GDVAELRVELTHGAETL--TLWQSTGPWG 177
A L SP L+ SC LRL Y + D ++L + + E+ LW + P
Sbjct: 65 KAVLLSPDLQAEEWSC-LRLVYQITTSSESLSDPSQLNLYMRFEDESFDRLLWSAKEP-S 122
Query: 178 PGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQ 237
W ++ F++ + ++AL +++
Sbjct: 123 DSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKM-------------------T 163
Query: 238 NKVCVEPQQLCDGEDN--CGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGP 295
C+E CD E+N CG ++ NP W G RN + P
Sbjct: 164 TGYCIE----CDFEENHLCGFVNRWNPNV--------------NWFVGGGSIRNVHSILP 205
Query: 296 ERPSWPRRDHSRNSAQGSFL----VSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGS 351
+ DH+ S G ++ V V A L SP + + C +YQ G+
Sbjct: 206 Q-------DHTFKSELGHYMYVDSVYVKHFQEVAQLISP-LTTAPMAGCLSFYYQIQQGN 257
Query: 352 EAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILL-AGQTGP-G 409
+ L T + R G AW V+ + YP +++ GP G
Sbjct: 258 DN---VFSLYTRDVAGLYEEIWKADRPG--NAAWNLAEVEFSAPYPMEVIFEVAFNGPKG 312
Query: 410 GVVGLDDLILSD-HCRPVSEV 429
G V LDD+ S HC+ +E+
Sbjct: 313 GYVALDDISFSPVHCQNQTEL 333
Score = 38.5 bits (88), Expect = 0.037
Identities = 43/168 (25%), Positives = 64/168 (38%), Gaps = 31/168 (18%)
Query: 892 GSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVL 951
GSC FE CG+ + L W + E GH+ + +T
Sbjct: 24 GSCAFEESTCGFDSV----LASLPW-------------------ILNEEGHYIYVDTS-F 59
Query: 952 GPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLH----SAQGQLAVWGAG 1007
G G A L S L A SCLR Y + ++ L+ +W A
Sbjct: 60 GKQGEKAVLLSPDLQAEEWSCLRLVYQITTSSESLSDPSQLNLYMRFEDESFDRLLWSA- 118
Query: 1008 GHRRHQWLEAQVEVA-SAKEFQIVFEATLGGQPALGPIALDDVEYLAG 1054
WL A +++ S+K+F+I+ E L GQ IAL +++ G
Sbjct: 119 KEPSDSWLIASLDLQNSSKKFKILIEGVL-GQGNTASIALFEIKMTTG 165
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 99.0 bits (245), Expect = 2e-20
Identities = 139/510 (27%), Positives = 204/510 (40%), Gaps = 77/510 (15%)
Query: 577 CNFERDT---CSWYPGHLSDTHWRWVESRGPDHDHTTG--------QGHFVLLDPTDPLA 625
C+FE D C W D W V + GP +TG +G ++ ++ ++
Sbjct: 41 CDFEDDAKPLCDWSQVSADDEDW--VRASGPSPTGSTGAPGGYPNGEGSYLHME-SNSFH 97
Query: 626 WGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETH----LWSRSGTQG 681
G A LLS P C+ F +H+ G G + GEE LW TQ
Sbjct: 98 RGGVARLLSPDLWEQGPL-CVHFAHHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQR 156
Query: 682 NRWHEAWATLSHQPGSHAQYQLLFEGLRDGY-HGTMALDDVAVRPGPC---WAPNYCSFE 737
W T++ G +L+FEG R + +ALD +++R G C CSF+
Sbjct: 157 PSW--MLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFD 214
Query: 738 DS----DCGFSPGGQGL-WRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQ 792
D + P G W ++ +SG GP D ++ G YM++D P GQ
Sbjct: 215 IPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFSSP-GSGCYMLLD--PKNARPGQ 271
Query: 793 TASLTSKEHRPLA-QPACLTFWYHGSLR--SPGT-LRVYLEERGRHQVLSL-SAHGGLAW 847
A L S P++ CL+F +H LR SPG L +Y G + +L S G W
Sbjct: 272 KAVLLS----PVSLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPNW 327
Query: 848 RLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQP-GSCDFESG---LCGW 903
+ S++ A + V VA+D + PC + CDFE C W
Sbjct: 328 QAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDATSI--APCGEGFPQCDFEDNAHPFCDW 385
Query: 904 SHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLG------TEAGHFAFFETGVLGPGGRA 957
+ G GG+ W G + PV H +G GH+ + E G++
Sbjct: 386 VQTS--GDGGH---WALG-----HKNGPV-HGMGPAGGFPNAGGHYIYLEADEFSQAGQS 434
Query: 958 AWLRSEPLPATPASCLRFWYHMGFPEHFYKGE---LKVLLHSAQGQ--LAVWGAGGHRRH 1012
L S P A C+ F YHM + GE L++LL S G + +W G +R
Sbjct: 435 VRLVSRPFCAPGDICVEFAYHM-----YGLGEGTMLELLLGSPAGSPPIPLWKRVGSQRP 489
Query: 1013 QWLEAQVEVASAKE--FQIVFEATLGGQPA 1040
W V V S + Q++F+ G A
Sbjct: 490 YWQNTSVTVPSGHQQPMQLIFKGIQGSNTA 519
Score = 61.2 bits (147), Expect = 5e-09
Identities = 101/448 (22%), Positives = 150/448 (33%), Gaps = 90/448 (20%)
Query: 8 LPALVLF--LAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFA 65
LP ++F GS+ + + S + CN VC + CS
Sbjct: 172 LPTRLMFEGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCS------------------- 212
Query: 66 CDFEQDPCGWRDIST-SGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEAS 124
D D C W I T SG W + + + G GP D + G YM + +
Sbjct: 213 FDIPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFS-SPGSGCYMLLDPKNARPGQ 271
Query: 125 TAALRSPTLREAASSCKLRLWYH-----AASGDVAELRVELTHGAETLTLWQSTGPWGPG 179
A L SP + SS L +H + G + + TL+ +G GP
Sbjct: 272 KAVLLSPV---SLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLF--SGQPGPN 326
Query: 180 WQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNK 239
WQ ++V + G + T AVA+D CG PQ
Sbjct: 327 WQAVSVNYTAV-GRIQFAVVGVFGKTPEPAVAVDATSIAPCGEGFPQ------------- 372
Query: 240 VCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEG----WSRNHRAGGP 295
CD EDN D W ++ G W+ H+ GP
Sbjct: 373 --------CDFEDNAHPFCD--------------------WVQTSGDGGHWALGHK-NGP 403
Query: 296 ERPSWPRRDHSRNSAQGSFLVS--VAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEA 353
P +L + ++ G L S F A G ++ Y G E
Sbjct: 404 VHGMGPAGGFPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLG-EG 462
Query: 354 GCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAY--PFQILLAGQTG--PG 409
L+L LG A P+ L +R G W V + S + P Q++ G G
Sbjct: 463 TMLELL---LGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTA 519
Query: 410 GVVGLDDLILSDHCRPVSEVSTLQPLPP 437
VV + ++++ PV + L P+ P
Sbjct: 520 SVVAMGFILINPGTCPVKVLPELPPVSP 547
Score = 34.3 bits (77), Expect = 0.69
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
Query: 503 WEDASVGRLQWRRVSAQESQGSSAAAAGH------FLSLQRAWGQLGAEARVLTPLLGPS 556
W S W R S GS+ A G+ +L ++ G AR+L+P L
Sbjct: 53 WSQVSADDEDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQ 112
Query: 557 GPSCELHLAYYL 568
GP C +H A+++
Sbjct: 113 GPLC-VHFAHHM 123
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 99.0 bits (245), Expect = 2e-20
Identities = 139/510 (27%), Positives = 204/510 (40%), Gaps = 77/510 (15%)
Query: 577 CNFERDT---CSWYPGHLSDTHWRWVESRGPDHDHTTG--------QGHFVLLDPTDPLA 625
C+FE D C W D W V + GP +TG +G ++ ++ ++
Sbjct: 41 CDFEDDAKPLCDWSQVSADDEDW--VRASGPSPTGSTGAPGGYPNGEGSYLHME-SNSFH 97
Query: 626 WGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETH----LWSRSGTQG 681
G A LLS P C+ F +H+ G G + GEE LW TQ
Sbjct: 98 RGGVARLLSPDLWEQGPL-CVHFAHHMFGLSWGAQLRLLLLSGEEGRRPDVLWKHWNTQR 156
Query: 682 NRWHEAWATLSHQPGSHAQYQLLFEGLRDGY-HGTMALDDVAVRPGPC---WAPNYCSFE 737
W T++ G +L+FEG R + +ALD +++R G C CSF+
Sbjct: 157 PSW--MLTTVTVPAGFTLPTRLMFEGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCSFD 214
Query: 738 DS----DCGFSPGGQGL-WRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQ 792
D + P G W ++ +SG GP D ++ G YM++D P GQ
Sbjct: 215 IPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFSSP-GSGCYMLLD--PKNARPGQ 271
Query: 793 TASLTSKEHRPLA-QPACLTFWYHGSLR--SPGT-LRVYLEERGRHQVLSL-SAHGGLAW 847
A L S P++ CL+F +H LR SPG L +Y G + +L S G W
Sbjct: 272 KAVLLS----PVSLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLFSGQPGPNW 327
Query: 848 RLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQP-GSCDFESG---LCGW 903
+ S++ A + V VA+D + PC + CDFE C W
Sbjct: 328 QAVSVNYTAVGRIQFAVVGVFGKTPEPAVAVDATSI--APCGEGFPQCDFEDNAHPFCDW 385
Query: 904 SHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLG------TEAGHFAFFETGVLGPGGRA 957
+ G GG+ W G + PV H +G GH+ + E G++
Sbjct: 386 VQTS--GDGGH---WALG-----HKNGPV-HGMGPAGGFPNAGGHYIYLEADEFSQAGQS 434
Query: 958 AWLRSEPLPATPASCLRFWYHMGFPEHFYKGE---LKVLLHSAQGQ--LAVWGAGGHRRH 1012
L S P A C+ F YHM + GE L++LL S G + +W G +R
Sbjct: 435 VRLVSRPFCAPGDICVEFAYHM-----YGLGEGTMLELLLGSPAGSPPIPLWKRVGSQRP 489
Query: 1013 QWLEAQVEVASAKE--FQIVFEATLGGQPA 1040
W V V S + Q++F+ G A
Sbjct: 490 YWQNTSVTVPSGHQQPMQLIFKGIQGSNTA 519
Score = 61.2 bits (147), Expect = 5e-09
Identities = 101/448 (22%), Positives = 150/448 (33%), Gaps = 90/448 (20%)
Query: 8 LPALVLF--LAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFA 65
LP ++F GS+ + + S + CN VC + CS
Sbjct: 172 LPTRLMFEGTRGSTAYLDIALDALSIRRGSCNRVCMMQTCS------------------- 212
Query: 66 CDFEQDPCGWRDIST-SGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEAS 124
D D C W I T SG W + + + G GP D + G YM + +
Sbjct: 213 FDIPNDLCDWTWIPTASGAKWTQKKGSSGKPGVGPDGDFS-SPGSGCYMLLDPKNARPGQ 271
Query: 125 TAALRSPTLREAASSCKLRLWYH-----AASGDVAELRVELTHGAETLTLWQSTGPWGPG 179
A L SP + SS L +H + G + + TL+ +G GP
Sbjct: 272 KAVLLSPV---SLSSGCLSFSFHYILRGQSPGAALHIYASVLGSIRKHTLF--SGQPGPN 326
Query: 180 WQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNK 239
WQ ++V + G + T AVA+D CG PQ
Sbjct: 327 WQAVSVNYTAV-GRIQFAVVGVFGKTPEPAVAVDATSIAPCGEGFPQ------------- 372
Query: 240 VCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEG----WSRNHRAGGP 295
CD EDN D W ++ G W+ H+ GP
Sbjct: 373 --------CDFEDNAHPFCD--------------------WVQTSGDGGHWALGHK-NGP 403
Query: 296 ERPSWPRRDHSRNSAQGSFLVS--VAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEA 353
P +L + ++ G L S F A G ++ Y G E
Sbjct: 404 VHGMGPAGGFPNAGGHYIYLEADEFSQAGQSVRLVSRPFCAPGDICVEFAYHMYGLG-EG 462
Query: 354 GCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAY--PFQILLAGQTG--PG 409
L+L LG A P+ L +R G W V + S + P Q++ G G
Sbjct: 463 TMLELL---LGSPAGSPPIPLWKRVGSQRPYWQNTSVTVPSGHQQPMQLIFKGIQGSNTA 519
Query: 410 GVVGLDDLILSDHCRPVSEVSTLQPLPP 437
VV + ++++ PV + L P+ P
Sbjct: 520 SVVAMGFILINPGTCPVKVLPELPPVSP 547
Score = 34.3 bits (77), Expect = 0.69
Identities = 21/72 (29%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
Query: 503 WEDASVGRLQWRRVSAQESQGSSAAAAGH------FLSLQRAWGQLGAEARVLTPLLGPS 556
W S W R S GS+ A G+ +L ++ G AR+L+P L
Sbjct: 53 WSQVSADDEDWVRASGPSPTGSTGAPGGYPNGEGSYLHMESNSFHRGGVARLLSPDLWEQ 112
Query: 557 GPSCELHLAYYL 568
GP C +H A+++
Sbjct: 113 GPLC-VHFAHHM 123
>gi|164698517 MAM domain containing 1 isoform 1 [Homo sapiens]
Length = 956
Score = 89.4 bits (220), Expect = 2e-17
Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 28/180 (15%)
Query: 573 REVSCNFE-----------RDTCSWYPGHLSDTHWRWVESRGPDHDHT-TGQGHFVLLDP 620
RE C FE D W + + ++ + GP+ D + + +G ++ ++
Sbjct: 744 REFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIET 803
Query: 621 TDPLAWGHSAHLLS-----RPQVPAAPTE---CLSFWYHLHGPQIGTLRLAMRREGE--- 669
+ P G A LLS P+ P PT C SF+YH++G IG L + +R +G+
Sbjct: 804 SRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTI 863
Query: 670 ETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLR-DGYHGTMALDDVAVRPGPC 728
E LWS SG +G RW+EA + +QL+FEG+R G G +A+DDV++ G C
Sbjct: 864 ENPLWSSSGNKGQRWNEAHVNIY----PITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 919
Score = 57.8 bits (138), Expect = 6e-08
Identities = 43/174 (24%), Positives = 80/174 (45%), Gaps = 19/174 (10%)
Query: 733 YCSFEDSD-CGFSPGGQGL--WRRQANASGHAAWGPPTDHTTETA---QGHYMVVDTSPD 786
+C FED + C F+ W +Q+ A+ + + P T + + +G YM ++TS
Sbjct: 747 HCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRP 806
Query: 787 ALPRGQTASLTS--------KEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGR----H 834
L G+ A L S + P C +F+YH + G L VYL +G+ +
Sbjct: 807 RL-EGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIEN 865
Query: 835 QVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPC 888
+ S S + G W +++ +++++FE + +A+DD+ + +G C
Sbjct: 866 PLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 919
Score = 56.6 bits (135), Expect = 1e-07
Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 915 SWDWGGGATPSRYPQ------PPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPL--- 965
++DW +T +R + P D + G++ G + + ET G A L S
Sbjct: 765 NFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIETSRPRLEGEKARLLSPVFSIA 823
Query: 966 ------PATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAV----WGAGGHRRHQWL 1015
P A C F+YHM + +H G L V L +GQ + W + G++ +W
Sbjct: 824 PKNPYGPTNTAYCFSFFYHM-YGQHI--GVLNVYLR-LKGQTTIENPLWSSSGNKGQRWN 879
Query: 1016 EAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPA 1075
EA V + FQ++FE + G G IA+DDV G+ +Q + A SV
Sbjct: 880 EAHVNIYPITSFQLIFEG-IRGPGIEGDIAIDDVSIAEGECAKQ------DLATKNSVDG 932
Query: 1076 VVGSA--LLLLMLLVLLGL 1092
VG + L ++VL+ +
Sbjct: 933 AVGILVHIWLFPIIVLISI 951
Score = 44.7 bits (104), Expect = 5e-04
Identities = 45/170 (26%), Positives = 66/170 (38%), Gaps = 21/170 (12%)
Query: 64 FACDFEQ-DPCGWRDISTSGYSWLRDRAGAA----LEGPGPHSDHTLGTDLGWYMAVGTH 118
F C FE + C + T + W + GP++D + G+ G+YM + T
Sbjct: 746 FHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIETS 804
Query: 119 RGK-EASTAALRSPTLREAASS---------CKLRLWYHAASGDVAELRVELTHGAETLT 168
R + E A L SP A + C +YH + L V L +T
Sbjct: 805 RPRLEGEKARLLSPVFSIAPKNPYGPTNTAYC-FSFFYHMYGQHIGVLNVYLRLKGQTTI 863
Query: 169 ---LWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
LW S+G G W E V I F++ F R G +A+DD+
Sbjct: 864 ENPLWSSSGNKGQRWNEAHVNIYPIT-SFQLIFEGIRGPGIEGDIAIDDV 912
Score = 39.3 bits (90), Expect = 0.021
Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 16/134 (11%)
Query: 301 PRRDHSRNSAQGSFLVSVAEP---GTPAILSSPEFQAS--------GTSNCSLVFYQYLS 349
P D S + + + P G A L SP F + T+ C FY ++
Sbjct: 786 PNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFY-HMY 844
Query: 350 GSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG 409
G G L ++L+ G P L G G W V+I FQ++ G GPG
Sbjct: 845 GQHIGVLNVYLRLKGQTTIENP--LWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPG 902
Query: 410 --GVVGLDDLILSD 421
G + +DD+ +++
Sbjct: 903 IEGDIAIDDVSIAE 916
>gi|38158013 MAM domain containing 1 isoform 2 [Homo sapiens]
Length = 727
Score = 89.4 bits (220), Expect = 2e-17
Identities = 57/180 (31%), Positives = 89/180 (49%), Gaps = 28/180 (15%)
Query: 573 REVSCNFE-----------RDTCSWYPGHLSDTHWRWVESRGPDHDHT-TGQGHFVLLDP 620
RE C FE D W + + ++ + GP+ D + + +G ++ ++
Sbjct: 515 REFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIET 574
Query: 621 TDPLAWGHSAHLLS-----RPQVPAAPTE---CLSFWYHLHGPQIGTLRLAMRREGE--- 669
+ P G A LLS P+ P PT C SF+YH++G IG L + +R +G+
Sbjct: 575 SRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTI 634
Query: 670 ETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLR-DGYHGTMALDDVAVRPGPC 728
E LWS SG +G RW+EA + +QL+FEG+R G G +A+DDV++ G C
Sbjct: 635 ENPLWSSSGNKGQRWNEAHVNIY----PITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 690
Score = 57.8 bits (138), Expect = 6e-08
Identities = 43/174 (24%), Positives = 80/174 (45%), Gaps = 19/174 (10%)
Query: 733 YCSFEDSD-CGFSPGGQGL--WRRQANASGHAAWGPPTDHTTETA---QGHYMVVDTSPD 786
+C FED + C F+ W +Q+ A+ + + P T + + +G YM ++TS
Sbjct: 518 HCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKEGFYMYIETSRP 577
Query: 787 ALPRGQTASLTS--------KEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGR----H 834
L G+ A L S + P C +F+YH + G L VYL +G+ +
Sbjct: 578 RL-EGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIEN 636
Query: 835 QVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPC 888
+ S S + G W +++ +++++FE + +A+DD+ + +G C
Sbjct: 637 PLWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPGIEGDIAIDDVSIAEGEC 690
Score = 56.6 bits (135), Expect = 1e-07
Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 33/199 (16%)
Query: 915 SWDWGGGATPSRYPQ------PPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPL--- 965
++DW +T +R + P D + G++ G + + ET G A L S
Sbjct: 536 NFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIETSRPRLEGEKARLLSPVFSIA 594
Query: 966 ------PATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAV----WGAGGHRRHQWL 1015
P A C F+YHM + +H G L V L +GQ + W + G++ +W
Sbjct: 595 PKNPYGPTNTAYCFSFFYHM-YGQHI--GVLNVYLR-LKGQTTIENPLWSSSGNKGQRWN 650
Query: 1016 EAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPA 1075
EA V + FQ++FE + G G IA+DDV G+ +Q + A SV
Sbjct: 651 EAHVNIYPITSFQLIFEG-IRGPGIEGDIAIDDVSIAEGECAKQ------DLATKNSVDG 703
Query: 1076 VVGSA--LLLLMLLVLLGL 1092
VG + L ++VL+ +
Sbjct: 704 AVGILVHIWLFPIIVLISI 722
Score = 44.7 bits (104), Expect = 5e-04
Identities = 45/170 (26%), Positives = 66/170 (38%), Gaps = 21/170 (12%)
Query: 64 FACDFEQ-DPCGWRDISTSGYSWLRDRAGAA----LEGPGPHSDHTLGTDLGWYMAVGTH 118
F C FE + C + T + W + GP++D + G+ G+YM + T
Sbjct: 517 FHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRS-GSKEGFYMYIETS 575
Query: 119 RGK-EASTAALRSPTLREAASS---------CKLRLWYHAASGDVAELRVELTHGAETLT 168
R + E A L SP A + C +YH + L V L +T
Sbjct: 576 RPRLEGEKARLLSPVFSIAPKNPYGPTNTAYC-FSFFYHMYGQHIGVLNVYLRLKGQTTI 634
Query: 169 ---LWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
LW S+G G W E V I F++ F R G +A+DD+
Sbjct: 635 ENPLWSSSGNKGQRWNEAHVNIYPIT-SFQLIFEGIRGPGIEGDIAIDDV 683
Score = 39.3 bits (90), Expect = 0.021
Identities = 35/134 (26%), Positives = 54/134 (40%), Gaps = 16/134 (11%)
Query: 301 PRRDHSRNSAQGSFLVSVAEP---GTPAILSSPEFQAS--------GTSNCSLVFYQYLS 349
P D S + + + P G A L SP F + T+ C FY ++
Sbjct: 557 PNADRSGSKEGFYMYIETSRPRLEGEKARLLSPVFSIAPKNPYGPTNTAYCFSFFY-HMY 615
Query: 350 GSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG 409
G G L ++L+ G P L G G W V+I FQ++ G GPG
Sbjct: 616 GQHIGVLNVYLRLKGQTTIENP--LWSSSGNKGQRWNEAHVNIYPITSFQLIFEGIRGPG 673
Query: 410 --GVVGLDDLILSD 421
G + +DD+ +++
Sbjct: 674 IEGDIAIDDVSIAE 687
>gi|24111244 MAM domain containing glycosylphosphatidylinositol
anchor 1 [Homo sapiens]
Length = 955
Score = 88.2 bits (217), Expect = 4e-17
Identities = 54/170 (31%), Positives = 89/170 (52%), Gaps = 22/170 (12%)
Query: 576 SCNFERDTCSWYPGHLSDTHWRWVESR------------GPDHDHT-TGQGHFVLLDPTD 622
+C+FE + Y L+D ++ W GP D + T +G+++ ++ +
Sbjct: 752 TCHFEDEKICGYTQDLTD-NFDWTRQNALTQNPKRSPNTGPPTDISGTPEGYYMFIETSR 810
Query: 623 PLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGE---ETHLWSRSGT 679
P G A L+S +A C+SF+YH++G IG+L L +R + +TH WS SG
Sbjct: 811 PRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSGN 870
Query: 680 QGNRWHEAWATLSHQPGSHAQYQLLFEGLR-DGYHGTMALDDVAVRPGPC 728
+GN W +A +S +Q++FEG+R GY G +A+DDV ++ G C
Sbjct: 871 KGNVWQQAHVPIS----PSGPFQIIFEGVRGPGYLGDIAIDDVTLKKGEC 916
Score = 68.2 bits (165), Expect = 4e-11
Identities = 54/180 (30%), Positives = 86/180 (47%), Gaps = 23/180 (12%)
Query: 727 PCWAPNYCSFEDSD-CGFSPGGQGL-----WRRQ----ANASGHAAWGPPTDHTTETAQG 776
P + N C FED CG++ Q L W RQ N GPPTD + T +G
Sbjct: 746 PNLSDNTCHFEDEKICGYT---QDLTDNFDWTRQNALTQNPKRSPNTGPPTD-ISGTPEG 801
Query: 777 HYMVVDTSPDALPR--GQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRH 834
+YM ++TS PR G A L S + A+ C++F+YH + G+L + + R +
Sbjct: 802 YYMFIETSR---PRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKG 858
Query: 835 QV----LSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQ 890
+ SLS + G W+ + + ++++FE V +A+DD+ L+ G CP+
Sbjct: 859 ALDTHAWSLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAIDDVTLKKGECPR 918
Score = 63.2 bits (152), Expect = 1e-09
Identities = 69/220 (31%), Positives = 102/220 (46%), Gaps = 27/220 (12%)
Query: 885 DGPCPQPGSCDFESG-LCGWSHLAWPGLGGYSWDWGGGAT--PSRYPQ--PPVDHTLGTE 939
+ P +C FE +CG++ + W T P R P PP D + GT
Sbjct: 744 NSPNLSDNTCHFEDEKICGYTQDL---TDNFDWTRQNALTQNPKRSPNTGPPTDIS-GTP 799
Query: 940 AGHFAFFETGVLGPGGRAAWLRSEPLPATPAS--CLRFWYHMGFPEHFYKGELKVLLHSA 997
G++ F ET G A L S PL A C+ F+YHM + +H G L +L+ S
Sbjct: 800 EGYYMFIETSRPRELGDRARLVS-PLYNASAKFYCVSFFYHM-YGKHI--GSLNLLVRSR 855
Query: 998 -QGQLAV--WGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAG 1054
+G L W G++ + W +A V ++ + FQI+FE + G LG IA+DDV G
Sbjct: 856 NKGALDTHAWSLSGNKGNVWQQAHVPISPSGPFQIIFEG-VRGPGYLGDIAIDDVTLKKG 914
Query: 1055 QHC--QQPAPS-----PGNTAAPGSVPAVVGSALLLLMLL 1087
+ C +Q P+ PG+ A S P + G + L+ L
Sbjct: 915 E-CPRKQTDPNKVVVMPGSGAPCQSSPQLWGPMAIFLLAL 953
Score = 55.5 bits (132), Expect = 3e-07
Identities = 52/190 (27%), Positives = 76/190 (40%), Gaps = 23/190 (12%)
Query: 66 CDFEQDP-CGWRDISTSGYSWLRDRAGAALEGP------GPHSDHTLGTDLGWYMAVGTH 118
C FE + CG+ T + W R A + P GP +D + GT G+YM + T
Sbjct: 753 CHFEDEKICGYTQDLTDNFDWTRQNA--LTQNPKRSPNTGPPTDIS-GTPEGYYMFIETS 809
Query: 119 RGKE-ASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVEL---THGAETLTLWQSTG 174
R +E A L SP +A + +YH + L + + GA W +G
Sbjct: 810 RPRELGDRARLVSPLYNASAKFYCVSFFYHMYGKHIGSLNLLVRSRNKGALDTHAWSLSG 869
Query: 175 PWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHH 234
G WQ+ V G F++ F R + G +A+DD+ P Q +
Sbjct: 870 NKGNVWQQAHVPISP-SGPFQIIFEGVRGPGYLGDIAIDDVTLKKGECPRKQTD------ 922
Query: 235 HCQNKVCVEP 244
NKV V P
Sbjct: 923 --PNKVVVMP 930
Score = 47.4 bits (111), Expect = 8e-05
Identities = 49/184 (26%), Positives = 72/184 (39%), Gaps = 20/184 (10%)
Query: 243 EPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERP--SW 300
EP + DN DE + + +F+ W R ++N P+R +
Sbjct: 741 EPINSPNLSDNTCHFEDEKICGYTQDLTDNFD-----WTRQNALTQN-----PKRSPNTG 790
Query: 301 PRRDHSRNSAQGSFLVSVAEP---GTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQ 357
P D S + + P G A L SP + AS C FY ++ G G L
Sbjct: 791 PPTDISGTPEGYYMFIETSRPRELGDRARLVSPLYNASAKFYCVSFFY-HMYGKHIGSLN 849
Query: 358 LFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPG--GVVGLD 415
L +++ GA G G W + V I + PFQI+ G GPG G + +D
Sbjct: 850 LLVRSRNKGALDTHAW--SLSGNKGNVWQQAHVPISPSGPFQIIFEGVRGPGYLGDIAID 907
Query: 416 DLIL 419
D+ L
Sbjct: 908 DVTL 911
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 79.3 bits (194), Expect = 2e-14
Identities = 45/163 (27%), Positives = 74/163 (45%), Gaps = 12/163 (7%)
Query: 574 EVSCNFERDTCSWYPGHLSDTHWRWVESR------GPDHDHTTGQGH-FVLLDPTDPLAW 626
+++CNFE C W D W ++ GP+ DHT G F + PT P
Sbjct: 344 KINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGR 403
Query: 627 GHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRR-EGEETHLWSRSGTQGNRWH 685
LLS P P CLSFWYH++G + L + + + E ++ + G G+ W+
Sbjct: 404 QERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWN 463
Query: 686 EAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPC 728
TL+ ++++ F ++ +ALDD+++ G C
Sbjct: 464 YGQVTLNET----VKFKVAFNAFKNKILSDIALDDISLTYGIC 502
Score = 64.7 bits (156), Expect = 5e-10
Identities = 49/165 (29%), Positives = 73/165 (44%), Gaps = 13/165 (7%)
Query: 893 SCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLG 952
+C+FE G C W W+ G+T S + P DHT G +G F+ + G
Sbjct: 346 NCNFEDGFCFWVQDL---NDDNEWERIQGSTFSPFTGPNFDHTFGNASG---FYISTPTG 399
Query: 953 PGGRAAWLRSEPLPATPA---SCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGH 1009
PGGR + LP P +CL FWYHM + E+ +K + + + + V+ G+
Sbjct: 400 PGGRQERVGLLSLPLDPTLEPACLSFWYHM-YGENVHKLSINI-SNDQNMEKTVFQKEGN 457
Query: 1010 RRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAG 1054
W QV + +F++ F A L IALDD+ G
Sbjct: 458 YGDNWNYGQVTLNETVKFKVAFNAF--KNKILSDIALDDISLTYG 500
Score = 61.6 bits (148), Expect = 4e-09
Identities = 45/159 (28%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Query: 734 CSFEDSDCGFSP--GGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRG 791
C+FED C + W R ++ GP DHT A G Y+ T P R
Sbjct: 347 CNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGG--RQ 404
Query: 792 QTASLTSKEHRPLAQPACLTFWYH--GSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRL 849
+ L S P +PACL+FWYH G ++ + ++ V + G W
Sbjct: 405 ERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNY 464
Query: 850 GSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPC 888
G + + ++V F A + S +ALDD+ L G C
Sbjct: 465 GQVTLNETVKFKVAFNAFKNKIL-SDIALDDISLTYGIC 502
Score = 60.8 bits (146), Expect = 7e-09
Identities = 42/151 (27%), Positives = 62/151 (41%), Gaps = 3/151 (1%)
Query: 66 CDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEAST 125
C+FE C W W R + GP+ DHT G G+Y++ T G
Sbjct: 347 CNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQER 406
Query: 126 AALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAE-TLTLWQSTGPWGPGWQELA 184
L S L L WYH +V +L + +++ T++Q G +G W
Sbjct: 407 VGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQ 466
Query: 185 VTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
VT F+V F+A +N +ALDD+
Sbjct: 467 VTLNE-TVKFKVAFNAFKNKI-LSDIALDDI 495
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/105 (33%), Positives = 48/105 (45%), Gaps = 12/105 (11%)
Query: 158 VELTHG--AETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
VE+ G A++L L TGP GP +++ TT R+ T + RG +
Sbjct: 580 VEIRDGEEADSLLLAVYTGP-GPV-KDVFSTTNRM-----TVLLITNDVLARGGFKANFT 632
Query: 216 EFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDE 260
+ G+P P C H C+N CV LCDG +C D SDE
Sbjct: 633 TGYHLGIPEP---CKADHFQCKNGECVPLVNLCDGHLHCEDGSDE 674
Score = 35.4 bits (80), Expect = 0.31
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 229 CPPGHHHCQNKV-CVEPQQLCDGEDNCGDLSDENPLTC 265
C PG C + + C++ CDGE NC D SDE+ C
Sbjct: 184 CLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMC 221
Score = 32.7 bits (73), Expect = 2.0
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 6/48 (12%)
Query: 453 LQDSCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDEQAC-----GTTD 494
+ + CK H C + CVP LCD C G DE C GTT+
Sbjct: 639 IPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTN 686
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 72.8 bits (177), Expect = 2e-12
Identities = 52/160 (32%), Positives = 78/160 (48%), Gaps = 17/160 (10%)
Query: 584 CSWYPGHLSDTHWRWVESR-GPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAP 642
C W + W + S+ GP DHT G G+F+ D G A L+S
Sbjct: 661 CHWEHDNHVQLKWSVLTSKTGPIQDHT-GDGNFIY-SQADENQKGKVARLVSPVVYSQNS 718
Query: 643 TECLSFWYHLHGPQIGTLRLAMRREGEETH---LWSRSGTQGNRWHEAWATLSHQPGSHA 699
C++FWYH+ G +GTLR+ +R + E + +W G QG+ W E L H+ S
Sbjct: 719 AHCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVWMAIGHQGDHWKEG-RVLLHK--SLK 775
Query: 700 QYQLLFEG-LRDGYHGTMALDDVAVRPGPCWAPNYCSFED 738
YQ++FEG + G G +A+DD+++ N+ S ED
Sbjct: 776 LYQVIFEGEIGKGNLGGIAVDDISIN-------NHISQED 808
Score = 52.4 bits (124), Expect = 2e-06
Identities = 42/139 (30%), Positives = 66/139 (47%), Gaps = 14/139 (10%)
Query: 930 PPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGE 989
P DHT G+F + + G A + A C+ FWYHM + G
Sbjct: 682 PIQDHT---GDGNFIYSQADENQKGKVARLVSPVVYSQNSAHCMTFWYHM---SGSHVGT 735
Query: 990 LKVLLHSAQGQ---LAVWGAGGHRRHQWLEAQVEV-ASAKEFQIVFEATLGGQPALGPIA 1045
L+V L + + VW A GH+ W E +V + S K +Q++FE + G+ LG IA
Sbjct: 736 LRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEI-GKGNLGGIA 794
Query: 1046 LDDV---EYLAGQHCQQPA 1061
+DD+ +++ + C +PA
Sbjct: 795 VDDISINNHISQEDCAKPA 813
Score = 49.7 bits (117), Expect = 2e-05
Identities = 57/235 (24%), Positives = 84/235 (35%), Gaps = 48/235 (20%)
Query: 58 PTLGAPFACDF----EQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYM 113
PT G F C+F + C W + W GP DHT + +
Sbjct: 644 PTYG--FNCEFGWGSHKTFCHWEHDNHVQLKW-----SVLTSKTGPIQDHTGDGNFIYSQ 696
Query: 114 AVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAE---TLTLW 170
A +GK A L SP + S+ + WYH + V LRV+L + +W
Sbjct: 697 ADENQKGK---VARLVSPVVYSQNSAHCMTFWYHMSGSHVGTLRVKLRYQKPEEYDQLVW 753
Query: 171 QSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCP 230
+ G G W+E V + ++V F + G +A+DD+
Sbjct: 754 MAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAVDDISI------------- 800
Query: 231 PGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEG 285
++H + C +P DL +NP I D ETG P EG
Sbjct: 801 --NNHISQEDCAKP----------ADLDKKNP-----EIKID-ETGSTPGYEGEG 837
Score = 43.9 bits (102), Expect = 9e-04
Identities = 39/141 (27%), Positives = 62/141 (43%), Gaps = 14/141 (9%)
Query: 764 GPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGT 823
GP DHT + G+++ + D +G+ A L S C+TFWYH S GT
Sbjct: 681 GPIQDHTGD---GNFIY--SQADENQKGKVARLVSPVVYSQNSAHCMTFWYHMSGSHVGT 735
Query: 824 LRVYLE----ERGRHQVLSLSAHGGLAWRLGSMDV-QAERAWRVVFEAVAAGVAHSYVAL 878
LRV L E V H G W+ G + + ++ + ++V+FE +A+
Sbjct: 736 LRVKLRYQKPEEYDQLVWMAIGHQGDHWKEGRVLLHKSLKLYQVIFEGEIGKGNLGGIAV 795
Query: 879 DDLLLQD----GPCPQPGSCD 895
DD+ + + C +P D
Sbjct: 796 DDISINNHISQEDCAKPADLD 816
>gi|239755252 PREDICTED: hypothetical protein [Homo sapiens]
Length = 377
Score = 63.9 bits (154), Expect = 8e-10
Identities = 77/327 (23%), Positives = 126/327 (38%), Gaps = 55/327 (16%)
Query: 265 CGRHIATDFETGLGPWNRSEG----WSRNHRAGGPERPSWPRRDHSRN-SAQGSFLVSVA 319
C + DFE GL + + W++ G P + DH+ + SA LVS
Sbjct: 63 CLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFY---DHNGDVSAHFLSLVSRV 119
Query: 320 EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRG 379
+ + ++ S + +C + FY Y S +G L + LQT G + L +
Sbjct: 120 DSISSSLRSRVFLPTNDQHDCQITFY-YFSCQVSGKLMVGLQTACGGPIQH---LWQNTA 175
Query: 380 ELGTAWVRDRVDIQSAYPFQILLAGQTG----PGGVVGLDDLILSDHCRPVSEVSTLQPL 435
L W R+ + IQS+ FQ++ GQ V+ +DD+ S C P ++ L
Sbjct: 176 ALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILL--- 232
Query: 436 PPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDF 495
C++ A +LC P LC F+ A E+ + C F
Sbjct: 233 ---------------------CQEALNAERELCHPDTDLCRFD---ATDEELRLCQACGF 268
Query: 496 ESPEAGGWEDASVGRLQWRRVSAQE--------SQGSSAAAAGHFLSLQRAWG----QLG 543
E +AS G++ W R A+E Q G+++ + G L
Sbjct: 269 EFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLD 328
Query: 544 AEARVLTPLLGPSGPSCELHLAYYLQS 570
+ A + + + G SC L Y ++S
Sbjct: 329 SRAYLNSSVCHCLGKSCHLQFYYAMES 355
Score = 40.8 bits (94), Expect = 0.007
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 6/130 (4%)
Query: 47 DEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSG-YSWLRDRAGAALEGPGPHSDHTL 105
D C + L AC FE D C W +++G SW+R +A
Sbjct: 247 DTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQG 306
Query: 106 GTDLGWYMAVGTHRGKEA----STAALRSPTLREAASSCKLRLWYHAASGDVAELRVELT 161
G D G+Y+ VG G S A L S SC L+ +Y+A V +R+
Sbjct: 307 GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQ-FYYAMESSVLRVRLYNN 365
Query: 162 HGAETLTLWQ 171
L L+Q
Sbjct: 366 KVRRKLHLFQ 375
Score = 34.7 bits (78), Expect = 0.53
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 894 CDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGP 953
CDFE GLC H+ SW G PP G + HF + V
Sbjct: 69 CDFEDGLC---HMTQDQSLQPSWTKRSGMIGL---SPPFYDHNGDVSAHFLSLVSRV--- 119
Query: 954 GGRAAWLRSEPLPAT--PASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLA--VWGAGGH 1009
++ LRS T C +Y+ G+L V L +A G +W
Sbjct: 120 DSISSSLRSRVFLPTNDQHDCQITFYYFSCQ---VSGKLMVGLQTACGGPIQHLWQNTAA 176
Query: 1010 RRHQWLEAQVEVASAKEFQIVFEATLGGQPALGP-IALDDVEYLAG 1054
+QW +++ S++ FQ+VFE + IA+DD+ + +G
Sbjct: 177 LPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
>gi|169201936 PREDICTED: hypothetical protein [Homo sapiens]
Length = 377
Score = 63.9 bits (154), Expect = 8e-10
Identities = 77/327 (23%), Positives = 126/327 (38%), Gaps = 55/327 (16%)
Query: 265 CGRHIATDFETGLGPWNRSEG----WSRNHRAGGPERPSWPRRDHSRN-SAQGSFLVSVA 319
C + DFE GL + + W++ G P + DH+ + SA LVS
Sbjct: 63 CLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFY---DHNGDVSAHFLSLVSRV 119
Query: 320 EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRG 379
+ + ++ S + +C + FY Y S +G L + LQT G + L +
Sbjct: 120 DSISSSLRSRVFLPTNDQHDCQITFY-YFSCQVSGKLMVGLQTACGGPIQH---LWQNTA 175
Query: 380 ELGTAWVRDRVDIQSAYPFQILLAGQTG----PGGVVGLDDLILSDHCRPVSEVSTLQPL 435
L W R+ + IQS+ FQ++ GQ V+ +DD+ S C P ++ L
Sbjct: 176 ALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILL--- 232
Query: 436 PPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDF 495
C++ A +LC P LC F+ A E+ + C F
Sbjct: 233 ---------------------CQEALNAERELCHPDTDLCRFD---ATDEELRLCQACGF 268
Query: 496 ESPEAGGWEDASVGRLQWRRVSAQE--------SQGSSAAAAGHFLSLQRAWG----QLG 543
E +AS G++ W R A+E Q G+++ + G L
Sbjct: 269 EFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLD 328
Query: 544 AEARVLTPLLGPSGPSCELHLAYYLQS 570
+ A + + + G SC L Y ++S
Sbjct: 329 SRAYLNSSVCHCLGKSCHLQFYYAMES 355
Score = 40.8 bits (94), Expect = 0.007
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 6/130 (4%)
Query: 47 DEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSG-YSWLRDRAGAALEGPGPHSDHTL 105
D C + L AC FE D C W +++G SW+R +A
Sbjct: 247 DTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQG 306
Query: 106 GTDLGWYMAVGTHRGKEA----STAALRSPTLREAASSCKLRLWYHAASGDVAELRVELT 161
G D G+Y+ VG G S A L S SC L+ +Y+A V +R+
Sbjct: 307 GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQ-FYYAMESSVLRVRLYNN 365
Query: 162 HGAETLTLWQ 171
L L+Q
Sbjct: 366 KVRRKLHLFQ 375
Score = 34.7 bits (78), Expect = 0.53
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 894 CDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGP 953
CDFE GLC H+ SW G PP G + HF + V
Sbjct: 69 CDFEDGLC---HMTQDQSLQPSWTKRSGMIGL---SPPFYDHNGDVSAHFLSLVSRV--- 119
Query: 954 GGRAAWLRSEPLPAT--PASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLA--VWGAGGH 1009
++ LRS T C +Y+ G+L V L +A G +W
Sbjct: 120 DSISSSLRSRVFLPTNDQHDCQITFYYFSCQ---VSGKLMVGLQTACGGPIQHLWQNTAA 176
Query: 1010 RRHQWLEAQVEVASAKEFQIVFEATLGGQPALGP-IALDDVEYLAG 1054
+QW +++ S++ FQ+VFE + IA+DD+ + +G
Sbjct: 177 LPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
>gi|169191966 PREDICTED: hypothetical protein [Homo sapiens]
Length = 377
Score = 63.9 bits (154), Expect = 8e-10
Identities = 77/327 (23%), Positives = 126/327 (38%), Gaps = 55/327 (16%)
Query: 265 CGRHIATDFETGLGPWNRSEG----WSRNHRAGGPERPSWPRRDHSRN-SAQGSFLVSVA 319
C + DFE GL + + W++ G P + DH+ + SA LVS
Sbjct: 63 CLNYERCDFEDGLCHMTQDQSLQPSWTKRSGMIGLSPPFY---DHNGDVSAHFLSLVSRV 119
Query: 320 EPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRG 379
+ + ++ S + +C + FY Y S +G L + LQT G + L +
Sbjct: 120 DSISSSLRSRVFLPTNDQHDCQITFY-YFSCQVSGKLMVGLQTACGGPIQH---LWQNTA 175
Query: 380 ELGTAWVRDRVDIQSAYPFQILLAGQTG----PGGVVGLDDLILSDHCRPVSEVSTLQPL 435
L W R+ + IQS+ FQ++ GQ V+ +DD+ S C P ++ L
Sbjct: 176 ALPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSGCLPANDGILL--- 232
Query: 436 PPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDF 495
C++ A +LC P LC F+ A E+ + C F
Sbjct: 233 ---------------------CQEALNAERELCHPDTDLCRFD---ATDEELRLCQACGF 268
Query: 496 ESPEAGGWEDASVGRLQWRRVSAQE--------SQGSSAAAAGHFLSLQRAWG----QLG 543
E +AS G++ W R A+E Q G+++ + G L
Sbjct: 269 EFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQGGDDEGYYVWVGAKHGFTLNHLD 328
Query: 544 AEARVLTPLLGPSGPSCELHLAYYLQS 570
+ A + + + G SC L Y ++S
Sbjct: 329 SRAYLNSSVCHCLGKSCHLQFYYAMES 355
Score = 40.8 bits (94), Expect = 0.007
Identities = 36/130 (27%), Positives = 50/130 (38%), Gaps = 6/130 (4%)
Query: 47 DEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSG-YSWLRDRAGAALEGPGPHSDHTL 105
D C + L AC FE D C W +++G SW+R +A
Sbjct: 247 DTDLCRFDATDEELRLCQACGFEFDMCEWTSEASAGQISWMRTKAREIPAFESTPQQDQG 306
Query: 106 GTDLGWYMAVGTHRGKEA----STAALRSPTLREAASSCKLRLWYHAASGDVAELRVELT 161
G D G+Y+ VG G S A L S SC L+ +Y+A V +R+
Sbjct: 307 GDDEGYYVWVGAKHGFTLNHLDSRAYLNSSVCHCLGKSCHLQ-FYYAMESSVLRVRLYNN 365
Query: 162 HGAETLTLWQ 171
L L+Q
Sbjct: 366 KVRRKLHLFQ 375
Score = 34.7 bits (78), Expect = 0.53
Identities = 43/166 (25%), Positives = 65/166 (39%), Gaps = 17/166 (10%)
Query: 894 CDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGP 953
CDFE GLC H+ SW G PP G + HF + V
Sbjct: 69 CDFEDGLC---HMTQDQSLQPSWTKRSGMIGL---SPPFYDHNGDVSAHFLSLVSRV--- 119
Query: 954 GGRAAWLRSEPLPAT--PASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLA--VWGAGGH 1009
++ LRS T C +Y+ G+L V L +A G +W
Sbjct: 120 DSISSSLRSRVFLPTNDQHDCQITFYYFSCQ---VSGKLMVGLQTACGGPIQHLWQNTAA 176
Query: 1010 RRHQWLEAQVEVASAKEFQIVFEATLGGQPALGP-IALDDVEYLAG 1054
+QW +++ S++ FQ+VFE + IA+DD+ + +G
Sbjct: 177 LPNQWERNVIKIQSSQRFQVVFEGQMASTYEQDEVIAIDDISFSSG 222
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 58.5 bits (140), Expect = 3e-08
Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 572 PREVSCNFE--RDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHS 629
P +CNF+ + C W H W S P+ +F+ L +D G
Sbjct: 641 PSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPDDRNFLRLQ-SDSQREGQY 699
Query: 630 AHLLSRP-QVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
A L+S P +P +P C+ F Y G + L++ E LW QG W
Sbjct: 700 ARLISPPVHLPRSPV-CMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGR 758
Query: 689 ATLSHQPGSHAQYQLLFEG-LRDGYHGTMALDDVAV 723
L P +YQ++FEG + G G +A+DD+ +
Sbjct: 759 IIL---PSYDMEYQIVFEGVIGKGRSGEIAIDDIRI 791
Score = 43.9 bits (102), Expect = 9e-04
Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 13/172 (7%)
Query: 60 LGAPFACDFE--QDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGT 117
L + F C+F+ ++PCGW WLR A+ P +D T D ++ + +
Sbjct: 640 LPSGFNCNFDFLEEPCGWM---YDHAKWLRT-TWASSSSP---NDRTFPDDRN-FLRLQS 691
Query: 118 HRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWG 177
+E A L SP + S + Y A G L+V E+ LW G
Sbjct: 692 DSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQG 751
Query: 178 PGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANC 229
W+ + ++++ F G +A+DD+ P NC
Sbjct: 752 GEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRI---STDVPLENC 800
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 58.5 bits (140), Expect = 3e-08
Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 572 PREVSCNFE--RDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHS 629
P +CNF+ + C W H W S P+ +F+ L +D G
Sbjct: 641 PSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPDDRNFLRLQ-SDSQREGQY 699
Query: 630 AHLLSRP-QVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
A L+S P +P +P C+ F Y G + L++ E LW QG W
Sbjct: 700 ARLISPPVHLPRSPV-CMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGR 758
Query: 689 ATLSHQPGSHAQYQLLFEG-LRDGYHGTMALDDVAV 723
L P +YQ++FEG + G G +A+DD+ +
Sbjct: 759 IIL---PSYDMEYQIVFEGVIGKGRSGEIAIDDIRI 791
Score = 43.9 bits (102), Expect = 9e-04
Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 13/172 (7%)
Query: 60 LGAPFACDFE--QDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGT 117
L + F C+F+ ++PCGW WLR A+ P +D T D ++ + +
Sbjct: 640 LPSGFNCNFDFLEEPCGWM---YDHAKWLRT-TWASSSSP---NDRTFPDDRN-FLRLQS 691
Query: 118 HRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWG 177
+E A L SP + S + Y A G L+V E+ LW G
Sbjct: 692 DSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQG 751
Query: 178 PGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANC 229
W+ + ++++ F G +A+DD+ P NC
Sbjct: 752 GEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRI---STDVPLENC 800
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 58.5 bits (140), Expect = 3e-08
Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 572 PREVSCNFE--RDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHS 629
P +CNF+ + C W H W S P+ +F+ L +D G
Sbjct: 641 PSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPDDRNFLRLQ-SDSQREGQY 699
Query: 630 AHLLSRP-QVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
A L+S P +P +P C+ F Y G + L++ E LW QG W
Sbjct: 700 ARLISPPVHLPRSPV-CMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGR 758
Query: 689 ATLSHQPGSHAQYQLLFEG-LRDGYHGTMALDDVAV 723
L P +YQ++FEG + G G +A+DD+ +
Sbjct: 759 IIL---PSYDMEYQIVFEGVIGKGRSGEIAIDDIRI 791
Score = 43.9 bits (102), Expect = 9e-04
Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 13/172 (7%)
Query: 60 LGAPFACDFE--QDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGT 117
L + F C+F+ ++PCGW WLR A+ P +D T D ++ + +
Sbjct: 640 LPSGFNCNFDFLEEPCGWM---YDHAKWLRT-TWASSSSP---NDRTFPDDRN-FLRLQS 691
Query: 118 HRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWG 177
+E A L SP + S + Y A G L+V E+ LW G
Sbjct: 692 DSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQG 751
Query: 178 PGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANC 229
W+ + ++++ F G +A+DD+ P NC
Sbjct: 752 GEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRI---STDVPLENC 800
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 58.5 bits (140), Expect = 3e-08
Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 572 PREVSCNFE--RDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHS 629
P +CNF+ + C W H W S P+ +F+ L +D G
Sbjct: 641 PSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPDDRNFLRLQ-SDSQREGQY 699
Query: 630 AHLLSRP-QVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
A L+S P +P +P C+ F Y G + L++ E LW QG W
Sbjct: 700 ARLISPPVHLPRSPV-CMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGR 758
Query: 689 ATLSHQPGSHAQYQLLFEG-LRDGYHGTMALDDVAV 723
L P +YQ++FEG + G G +A+DD+ +
Sbjct: 759 IIL---PSYDMEYQIVFEGVIGKGRSGEIAIDDIRI 791
Score = 43.9 bits (102), Expect = 9e-04
Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 13/172 (7%)
Query: 60 LGAPFACDFE--QDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGT 117
L + F C+F+ ++PCGW WLR A+ P +D T D ++ + +
Sbjct: 640 LPSGFNCNFDFLEEPCGWM---YDHAKWLRT-TWASSSSP---NDRTFPDDRN-FLRLQS 691
Query: 118 HRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWG 177
+E A L SP + S + Y A G L+V E+ LW G
Sbjct: 692 DSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQG 751
Query: 178 PGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANC 229
W+ + ++++ F G +A+DD+ P NC
Sbjct: 752 GEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRI---STDVPLENC 800
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 58.5 bits (140), Expect = 3e-08
Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 572 PREVSCNFE--RDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHS 629
P +CNF+ + C W H W S P+ +F+ L +D G
Sbjct: 641 PSGFNCNFDFLEEPCGWMYDHAKWLRTTWASSSSPNDRTFPDDRNFLRLQ-SDSQREGQY 699
Query: 630 AHLLSRP-QVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
A L+S P +P +P C+ F Y G + L++ E LW QG W
Sbjct: 700 ARLISPPVHLPRSPV-CMEFQYQATGGRGVALQVVREASQESKLLWVIREDQGGEWKHGR 758
Query: 689 ATLSHQPGSHAQYQLLFEG-LRDGYHGTMALDDVAV 723
L P +YQ++FEG + G G +A+DD+ +
Sbjct: 759 IIL---PSYDMEYQIVFEGVIGKGRSGEIAIDDIRI 791
Score = 43.9 bits (102), Expect = 9e-04
Identities = 40/172 (23%), Positives = 65/172 (37%), Gaps = 13/172 (7%)
Query: 60 LGAPFACDFE--QDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGT 117
L + F C+F+ ++PCGW WLR A+ P +D T D ++ + +
Sbjct: 640 LPSGFNCNFDFLEEPCGWM---YDHAKWLRT-TWASSSSP---NDRTFPDDRN-FLRLQS 691
Query: 118 HRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWG 177
+E A L SP + S + Y A G L+V E+ LW G
Sbjct: 692 DSQREGQYARLISPPVHLPRSPVCMEFQYQATGGRGVALQVVREASQESKLLWVIREDQG 751
Query: 178 PGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANC 229
W+ + ++++ F G +A+DD+ P NC
Sbjct: 752 GEWKHGRIILPSYDMEYQIVFEGVIGKGRSGEIAIDDIRI---STDVPLENC 800
>gi|75709198 nephronectin [Homo sapiens]
Length = 565
Score = 57.0 bits (136), Expect = 1e-07
Identities = 49/157 (31%), Positives = 74/157 (47%), Gaps = 20/157 (12%)
Query: 576 SCNFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSR 635
SCNF+ C W +D HW P D GQ L + A G A L
Sbjct: 421 SCNFDHGLCGWIREKDNDLHWE------PIRDPAGGQ----YLTVSAAKAPGGKAARLVL 470
Query: 636 P--QVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEE-THLWSRSGTQGNRWHEAWATLS 692
P ++ + CLSF + + G GTL++ +R+ G LW R+G G+ W + TL
Sbjct: 471 PLGRLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHGAHGAALWGRNG--GHGWRQTQITLR 528
Query: 693 HQPGSHAQYQLLFEG-LRDGYHGTMALDDVAVRPGPC 728
G+ + ++F+G R G+ G + LDDV+++ G C
Sbjct: 529 ---GADIK-SVVFKGEKRRGHTGEIGLDDVSLKKGHC 561
Score = 48.1 bits (113), Expect = 5e-05
Identities = 46/178 (25%), Positives = 73/178 (41%), Gaps = 19/178 (10%)
Query: 714 GTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTET 773
G A D+ PG + C+F+ CG W R+ + H W P D
Sbjct: 404 GVSADDEAKDDPGVL--VHSCNFDHGLCG--------WIREKDNDLH--WEPIRD----P 447
Query: 774 AQGHYMVVDTSPDALPRGQTASLTSKEHRPL-AQPACLTFWYHGSLRSPGTLRVYLEERG 832
A G Y+ V + P G+ A L R + + CL+F + + GTL+V++ + G
Sbjct: 448 AGGQYLTVSAAK--APGGKAARLVLPLGRLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHG 505
Query: 833 RHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQ 890
H +GG WR + ++ VVF+ + LDD+ L+ G C +
Sbjct: 506 AHGAALWGRNGGHGWRQTQITLRGADIKSVVFKGEKRRGHTGEIGLDDVSLKKGHCSE 563
Score = 43.1 bits (100), Expect = 0.001
Identities = 54/181 (29%), Positives = 73/181 (40%), Gaps = 34/181 (18%)
Query: 884 QDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHF 943
+D P SC+F+ GLCGW L W+ P R P AG
Sbjct: 412 KDDPGVLVHSCNFDHGLCGWIREKDNDL---HWE------PIRDP-----------AGGQ 451
Query: 944 AFFETGVLGPGGRAAWLRSEPLPATPAS---CLRFWYHMGFPEHFYKGELKVLL--HSAQ 998
+ PGG+AA L PL S CL F + + + G L+V + H A
Sbjct: 452 YLTVSAAKAPGGKAARL-VLPLGRLMHSGDLCLSFRHKV---TGLHSGTLQVFVRKHGAH 507
Query: 999 GQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQ 1058
G A+WG G H W + Q+ + A +VF+ + G I LDDV G HC
Sbjct: 508 G-AALWGRNG--GHGWRQTQITLRGADIKSVVFKGE-KRRGHTGEIGLDDVSLKKG-HCS 562
Query: 1059 Q 1059
+
Sbjct: 563 E 563
Score = 41.2 bits (95), Expect = 0.006
Identities = 42/157 (26%), Positives = 61/157 (38%), Gaps = 29/157 (18%)
Query: 65 ACDFEQDPCGWRDISTSGYSW--LRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKE 122
+C+F+ CGW + W +RD AG G Y+ V +
Sbjct: 421 SCNFDHGLCGWIREKDNDLHWEPIRDPAG------------------GQYLTVSAAKAPG 462
Query: 123 ASTAALRSPTLREAASSCKLRLWYHAASG-DVAELRVEL-THGAETLTLWQSTGPWGPGW 180
A L P R S + H +G L+V + HGA LW G G GW
Sbjct: 463 GKAARLVLPLGRLMHSGDLCLSFRHKVTGLHSGTLQVFVRKHGAHGAALWGRNG--GHGW 520
Query: 181 QELAVTTGRIRG-DFR-VTFSATRNATHRGAVALDDL 215
++ +T +RG D + V F + H G + LDD+
Sbjct: 521 RQTQIT---LRGADIKSVVFKGEKRRGHTGEIGLDDV 554
>gi|61744471 low density lipoprotein receptor-related protein 8
isoform 1 precursor [Homo sapiens]
Length = 963
Score = 53.9 bits (128), Expect = 8e-07
Identities = 76/298 (25%), Positives = 107/298 (35%), Gaps = 56/298 (18%)
Query: 212 LDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIAT 271
LD + DC P+ C C N C+ + CDGE+ C D SDE+ TC + +
Sbjct: 73 LDHSDEDDC----PKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCP 128
Query: 272 DFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGTPAILSSPE 331
+ GP +H+ SW R D ++ G+ E G + + E
Sbjct: 129 AEKLSCGP--------TSHKC---VPASW-RCDGEKDCEGGA-----DEAGCATLCAPHE 171
Query: 332 FQASGTSNCSLVFY-----QYLSGS-EAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTA- 384
FQ S + VF GS E GC GP R G+ G A
Sbjct: 172 FQCGNRSCLAAVFVCDGDDDCGDGSDERGCAD---PACGPREFRC-------GGDGGGAC 221
Query: 385 ----WVRDR-VDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEVS--TLQPLPP 437
WV DR D + L G+ GPG C S+ + + + +
Sbjct: 222 IPERWVCDRQFDCEDRSDEAAELCGRPGPGATSA------PAACATASQFACRSGECVHL 275
Query: 438 GPRAPAPQPLPPSSRLQD----SCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDEQAC 490
G R + S D +C+ CGD CV + C+ E+ C G DE C
Sbjct: 276 GWRCDGDRDCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Score = 37.0 bits (84), Expect = 0.11
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 457 CKQGHLACGDL---CVPPEQLCDFEEQCAGGEDEQACGT 492
C L+CG CVP CD E+ C GG DE C T
Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCAT 165
Score = 35.4 bits (80), Expect = 0.31
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 206 HRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDEN 261
H A A D L G P +C C+N+ C+ CD +D+C D SDE+
Sbjct: 28 HLAAAAADPL----LGGQGPAKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED 79
Score = 30.8 bits (68), Expect = 7.6
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 16/74 (21%)
Query: 219 DCGLPTPQANCPPG-----HHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCG------- 266
DC + +A+CP G C + CV + C+ E +C D SDE G
Sbjct: 284 DCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHN 343
Query: 267 ----RHIATDFETG 276
HI TD + G
Sbjct: 344 NGGCSHICTDLKIG 357
>gi|65301119 low density lipoprotein receptor-related protein 8
isoform 4 precursor [Homo sapiens]
Length = 904
Score = 53.9 bits (128), Expect = 8e-07
Identities = 76/298 (25%), Positives = 107/298 (35%), Gaps = 56/298 (18%)
Query: 212 LDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIAT 271
LD + DC P+ C C N C+ + CDGE+ C D SDE+ TC + +
Sbjct: 73 LDHSDEDDC----PKKTCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCP 128
Query: 272 DFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGTPAILSSPE 331
+ GP +H+ SW R D ++ G+ E G + + E
Sbjct: 129 AEKLSCGP--------TSHKC---VPASW-RCDGEKDCEGGA-----DEAGCATLCAPHE 171
Query: 332 FQASGTSNCSLVFY-----QYLSGS-EAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTA- 384
FQ S + VF GS E GC GP R G+ G A
Sbjct: 172 FQCGNRSCLAAVFVCDGDDDCGDGSDERGCAD---PACGPREFRC-------GGDGGGAC 221
Query: 385 ----WVRDR-VDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEVS--TLQPLPP 437
WV DR D + L G+ GPG C S+ + + + +
Sbjct: 222 IPERWVCDRQFDCEDRSDEAAELCGRPGPGATSA------PAACATASQFACRSGECVHL 275
Query: 438 GPRAPAPQPLPPSSRLQD----SCKQGHLACGD-LCVPPEQLCDFEEQCAGGEDEQAC 490
G R + S D +C+ CGD CV + C+ E+ C G DE C
Sbjct: 276 GWRCDGDRDCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333
Score = 37.0 bits (84), Expect = 0.11
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 3/39 (7%)
Query: 457 CKQGHLACGDL---CVPPEQLCDFEEQCAGGEDEQACGT 492
C L+CG CVP CD E+ C GG DE C T
Sbjct: 127 CPAEKLSCGPTSHKCVPASWRCDGEKDCEGGADEAGCAT 165
Score = 35.4 bits (80), Expect = 0.31
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 4/56 (7%)
Query: 206 HRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDEN 261
H A A D L G P +C C+N+ C+ CD +D+C D SDE+
Sbjct: 28 HLAAAAADPL----LGGQGPAKDCEKDQFQCRNERCIPSVWRCDEDDDCLDHSDED 79
Score = 30.8 bits (68), Expect = 7.6
Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 16/74 (21%)
Query: 219 DCGLPTPQANCPPG-----HHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCG------- 266
DC + +A+CP G C + CV + C+ E +C D SDE G
Sbjct: 284 DCKDKSDEADCPLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHN 343
Query: 267 ----RHIATDFETG 276
HI TD + G
Sbjct: 344 NGGCSHICTDLKIG 357
>gi|110735404 protein tyrosine phosphatase, receptor type, U isoform
1 precursor [Homo sapiens]
Length = 1436
Score = 52.4 bits (124), Expect = 2e-06
Identities = 59/212 (27%), Positives = 94/212 (44%), Gaps = 31/212 (14%)
Query: 569 QSQPREVSCNFERDT-----CSWYPGHLSDTHWRWVE----SRGP-DHDHTTGQGHFVLL 618
+++ C FE + C + D W V +R P D H G ++++
Sbjct: 19 ETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPH----GSYLMV 74
Query: 619 DPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLH---GPQIGTLRLAMRREGEE--THL 673
+ T A G AH++ + + T C+ F Y L+ G GTL + +R G + +
Sbjct: 75 N-TSQHAPGQRAHVIFQ-SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAV 132
Query: 674 WSRSGTQGNRWHEA-WATLSHQPGSHAQYQLLFEGL-RDGYHGTMALDDVAVRPGPC-WA 730
W+ +G+ G +WH+A A + P +YQ+LFE L G M LDD+ + PC A
Sbjct: 133 WNMTGSHGRQWHQAELAVSTFWPN---EYQVLFEALISPDRRGYMGLDDILLLSYPCAKA 189
Query: 731 PNYCSFEDSDCGFSPGGQGLWRRQANASGHAA 762
P++ D + GQ Q A+G AA
Sbjct: 190 PHFSRLGDVEVN---AGQNA-SFQCMAAGRAA 217
Score = 44.3 bits (103), Expect = 7e-04
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
P T + G Y++V+TS A + S F Y SPGTL
Sbjct: 58 PGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHSPGTL 117
Query: 825 RVYLEERGR---HQVLSLSAHGGLAWRLGSMDVQA--ERAWRVVFEAVAAGVAHSYVALD 879
VY+ G V +++ G W + V ++V+FEA+ + Y+ LD
Sbjct: 118 GVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLD 177
Query: 880 DLLLQDGPC 888
D+LL PC
Sbjct: 178 DILLLSYPC 186
Score = 40.8 bits (94), Expect = 0.007
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 941 GHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQ 1000
G + T PG RA + + L C++F Y + + G L V + G
Sbjct: 69 GSYLMVNTSQHAPGQRAHVI-FQSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGP 127
Query: 1001 L--AVWGAGGHRRHQWLEAQVEVAS--AKEFQIVFEATLGGQPALGPIALDDVEYLA 1053
L AVW G QW +A++ V++ E+Q++FEA + G + LDD+ L+
Sbjct: 128 LGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALI-SPDRRGYMGLDDILLLS 183
Score = 36.2 bits (82), Expect = 0.18
Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 26/174 (14%)
Query: 57 SPTLGAPFA-CDFEQD-----PCGWRDISTSGYSWLRDRAGAALEGPG--PHSDHTLGTD 108
+P P A C FE+ PC + + W + R P PH
Sbjct: 17 APETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPH-------- 68
Query: 109 LGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGD-----VAELRVELTHG 163
G Y+ V T + A + +L E + C ++ Y S D + V + G
Sbjct: 69 -GSYLMVNTSQHAPGQRAHVIFQSLSENDTHC-VQFSYFLYSRDGHSPGTLGVYVRVNGG 126
Query: 164 AETLTLWQSTGPWGPGWQ--ELAVTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
+W TG G W ELAV+T +++V F A + RG + LDD+
Sbjct: 127 PLGSAVWNMTGSHGRQWHQAELAVSTFW-PNEYQVLFEALISPDRRGYMGLDDI 179
>gi|110735406 protein tyrosine phosphatase, receptor type, U isoform
2 precursor [Homo sapiens]
Length = 1442
Score = 52.4 bits (124), Expect = 2e-06
Identities = 59/212 (27%), Positives = 94/212 (44%), Gaps = 31/212 (14%)
Query: 569 QSQPREVSCNFERDT-----CSWYPGHLSDTHWRWVE----SRGP-DHDHTTGQGHFVLL 618
+++ C FE + C + D W V +R P D H G ++++
Sbjct: 19 ETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPH----GSYLMV 74
Query: 619 DPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLH---GPQIGTLRLAMRREGEE--THL 673
+ T A G AH++ + + T C+ F Y L+ G GTL + +R G + +
Sbjct: 75 N-TSQHAPGQRAHVIFQ-SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAV 132
Query: 674 WSRSGTQGNRWHEA-WATLSHQPGSHAQYQLLFEGL-RDGYHGTMALDDVAVRPGPC-WA 730
W+ +G+ G +WH+A A + P +YQ+LFE L G M LDD+ + PC A
Sbjct: 133 WNMTGSHGRQWHQAELAVSTFWPN---EYQVLFEALISPDRRGYMGLDDILLLSYPCAKA 189
Query: 731 PNYCSFEDSDCGFSPGGQGLWRRQANASGHAA 762
P++ D + GQ Q A+G AA
Sbjct: 190 PHFSRLGDVEVN---AGQNA-SFQCMAAGRAA 217
Score = 44.3 bits (103), Expect = 7e-04
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
P T + G Y++V+TS A + S F Y SPGTL
Sbjct: 58 PGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHSPGTL 117
Query: 825 RVYLEERGR---HQVLSLSAHGGLAWRLGSMDVQA--ERAWRVVFEAVAAGVAHSYVALD 879
VY+ G V +++ G W + V ++V+FEA+ + Y+ LD
Sbjct: 118 GVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLD 177
Query: 880 DLLLQDGPC 888
D+LL PC
Sbjct: 178 DILLLSYPC 186
Score = 40.8 bits (94), Expect = 0.007
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 941 GHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQ 1000
G + T PG RA + + L C++F Y + + G L V + G
Sbjct: 69 GSYLMVNTSQHAPGQRAHVI-FQSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGP 127
Query: 1001 L--AVWGAGGHRRHQWLEAQVEVAS--AKEFQIVFEATLGGQPALGPIALDDVEYLA 1053
L AVW G QW +A++ V++ E+Q++FEA + G + LDD+ L+
Sbjct: 128 LGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALI-SPDRRGYMGLDDILLLS 183
Score = 36.2 bits (82), Expect = 0.18
Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 26/174 (14%)
Query: 57 SPTLGAPFA-CDFEQD-----PCGWRDISTSGYSWLRDRAGAALEGPG--PHSDHTLGTD 108
+P P A C FE+ PC + + W + R P PH
Sbjct: 17 APETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPH-------- 68
Query: 109 LGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGD-----VAELRVELTHG 163
G Y+ V T + A + +L E + C ++ Y S D + V + G
Sbjct: 69 -GSYLMVNTSQHAPGQRAHVIFQSLSENDTHC-VQFSYFLYSRDGHSPGTLGVYVRVNGG 126
Query: 164 AETLTLWQSTGPWGPGWQ--ELAVTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
+W TG G W ELAV+T +++V F A + RG + LDD+
Sbjct: 127 PLGSAVWNMTGSHGRQWHQAELAVSTFW-PNEYQVLFEALISPDRRGYMGLDDI 179
>gi|110735402 protein tyrosine phosphatase, receptor type, U isoform
3 precursor [Homo sapiens]
Length = 1446
Score = 52.4 bits (124), Expect = 2e-06
Identities = 59/212 (27%), Positives = 94/212 (44%), Gaps = 31/212 (14%)
Query: 569 QSQPREVSCNFERDT-----CSWYPGHLSDTHWRWVE----SRGP-DHDHTTGQGHFVLL 618
+++ C FE + C + D W V +R P D H G ++++
Sbjct: 19 ETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPH----GSYLMV 74
Query: 619 DPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLH---GPQIGTLRLAMRREGEE--THL 673
+ T A G AH++ + + T C+ F Y L+ G GTL + +R G + +
Sbjct: 75 N-TSQHAPGQRAHVIFQ-SLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGPLGSAV 132
Query: 674 WSRSGTQGNRWHEA-WATLSHQPGSHAQYQLLFEGL-RDGYHGTMALDDVAVRPGPC-WA 730
W+ +G+ G +WH+A A + P +YQ+LFE L G M LDD+ + PC A
Sbjct: 133 WNMTGSHGRQWHQAELAVSTFWPN---EYQVLFEALISPDRRGYMGLDDILLLSYPCAKA 189
Query: 731 PNYCSFEDSDCGFSPGGQGLWRRQANASGHAA 762
P++ D + GQ Q A+G AA
Sbjct: 190 PHFSRLGDVEVN---AGQNA-SFQCMAAGRAA 217
Score = 44.3 bits (103), Expect = 7e-04
Identities = 35/129 (27%), Positives = 52/129 (40%), Gaps = 5/129 (3%)
Query: 765 PPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTL 824
P T + G Y++V+TS A + S F Y SPGTL
Sbjct: 58 PGTRAPADLPHGSYLMVNTSQHAPGQRAHVIFQSLSENDTHCVQFSYFLYSRDGHSPGTL 117
Query: 825 RVYLEERGR---HQVLSLSAHGGLAWRLGSMDVQA--ERAWRVVFEAVAAGVAHSYVALD 879
VY+ G V +++ G W + V ++V+FEA+ + Y+ LD
Sbjct: 118 GVYVRVNGGPLGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALISPDRRGYMGLD 177
Query: 880 DLLLQDGPC 888
D+LL PC
Sbjct: 178 DILLLSYPC 186
Score = 40.8 bits (94), Expect = 0.007
Identities = 33/117 (28%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 941 GHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQ 1000
G + T PG RA + + L C++F Y + + G L V + G
Sbjct: 69 GSYLMVNTSQHAPGQRAHVI-FQSLSENDTHCVQFSYFLYSRDGHSPGTLGVYVRVNGGP 127
Query: 1001 L--AVWGAGGHRRHQWLEAQVEVAS--AKEFQIVFEATLGGQPALGPIALDDVEYLA 1053
L AVW G QW +A++ V++ E+Q++FEA + G + LDD+ L+
Sbjct: 128 LGSAVWNMTGSHGRQWHQAELAVSTFWPNEYQVLFEALI-SPDRRGYMGLDDILLLS 183
Score = 36.2 bits (82), Expect = 0.18
Identities = 44/174 (25%), Positives = 66/174 (37%), Gaps = 26/174 (14%)
Query: 57 SPTLGAPFA-CDFEQD-----PCGWRDISTSGYSWLRDRAGAALEGPG--PHSDHTLGTD 108
+P P A C FE+ PC + + W + R P PH
Sbjct: 17 APETETPAAGCTFEEASDPAVPCEYSQAQYDDFQWEQVRIHPGTRAPADLPH-------- 68
Query: 109 LGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGD-----VAELRVELTHG 163
G Y+ V T + A + +L E + C ++ Y S D + V + G
Sbjct: 69 -GSYLMVNTSQHAPGQRAHVIFQSLSENDTHC-VQFSYFLYSRDGHSPGTLGVYVRVNGG 126
Query: 164 AETLTLWQSTGPWGPGWQ--ELAVTTGRIRGDFRVTFSATRNATHRGAVALDDL 215
+W TG G W ELAV+T +++V F A + RG + LDD+
Sbjct: 127 PLGSAVWNMTGSHGRQWHQAELAVSTFW-PNEYQVLFEALISPDRRGYMGLDDI 179
>gi|157419150 protein tyrosine phosphatase, receptor type, M isoform
2 precursor [Homo sapiens]
Length = 1452
Score = 52.0 bits (123), Expect = 3e-06
Identities = 49/197 (24%), Positives = 80/197 (40%), Gaps = 26/197 (13%)
Query: 577 CNFER--DTCSWYPGHLSDTHWRWVES-RGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLL 633
C F+ TC + D +W V + P D G F+L++ + G AHLL
Sbjct: 27 CLFDEPYSTCGYSQSEGDDFNWEQVNTLTKPTSDPWMPSGSFMLVNASGRPE-GQRAHLL 85
Query: 634 SRPQVPAAPTECLSFWYHLHG-----PQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
PQ+ T C+ F Y + P + + + + +W+ SG W+ A
Sbjct: 86 L-PQLKENDTHCIDFHYFVSSKSNSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAE 144
Query: 689 ATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCW--------------APNYC 734
+S + YQ++FE + G+ G +A+D+V V PC A +
Sbjct: 145 LAISTFWPNF--YQVIFEVITSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFA 202
Query: 735 SFEDSDCGFSPGGQGLW 751
+F+ S G + G LW
Sbjct: 203 TFQCSAIGRTVAGDRLW 219
>gi|157419152 protein tyrosine phosphatase, receptor type, M isoform
1 precursor [Homo sapiens]
Length = 1465
Score = 52.0 bits (123), Expect = 3e-06
Identities = 49/197 (24%), Positives = 80/197 (40%), Gaps = 26/197 (13%)
Query: 577 CNFER--DTCSWYPGHLSDTHWRWVES-RGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLL 633
C F+ TC + D +W V + P D G F+L++ + G AHLL
Sbjct: 27 CLFDEPYSTCGYSQSEGDDFNWEQVNTLTKPTSDPWMPSGSFMLVNASGRPE-GQRAHLL 85
Query: 634 SRPQVPAAPTECLSFWYHLHG-----PQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAW 688
PQ+ T C+ F Y + P + + + + +W+ SG W+ A
Sbjct: 86 L-PQLKENDTHCIDFHYFVSSKSNSPPGLLNVYVKVNNGPLGNPIWNISGDPTRTWNRAE 144
Query: 689 ATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCW--------------APNYC 734
+S + YQ++FE + G+ G +A+D+V V PC A +
Sbjct: 145 LAISTFWPNF--YQVIFEVITSGHQGYLAIDEVKVLGHPCTRTPHFLRIQNVEVNAGQFA 202
Query: 735 SFEDSDCGFSPGGQGLW 751
+F+ S G + G LW
Sbjct: 203 TFQCSAIGRTVAGDRLW 219
>gi|208431815 protein tyrosine phosphatase, receptor type, K isoform a
[Homo sapiens]
Length = 1446
Score = 51.6 bits (122), Expect = 4e-06
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 865 EAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWD------W 918
+ AA ++VAL LLL P F +G C + PG Y D W
Sbjct: 2 DTTAAAALPAFVAL--LLLSPWPLLGSAQGQFSAGGCTFDD--GPGACDYHQDLYDDFEW 57
Query: 919 GGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYH 978
+ + PP G + ++ PG +A L+ + C+ F Y
Sbjct: 58 VHVSAQEPHYLPPE-----MPQGSYMIVDSSDHDPGEKAR-LQLPTMKENDTHCIDFSYL 111
Query: 979 MGFPEHFYKGELKVLLHSAQGQLA--VWGAGGHRRHQWLEAQVEVAS--AKEFQIVFEAT 1034
+ + G L +L+ +G LA +W G WL A++ V++ E+Q++FEA
Sbjct: 112 LYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAE 171
Query: 1035 LGGQPALGPIALDDVEYLA 1053
+ G + G IA+DD++ L+
Sbjct: 172 VSGGRS-GYIAIDDIQVLS 189
Score = 46.6 bits (109), Expect = 1e-04
Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 21/173 (12%)
Query: 569 QSQPREVSCNFERD--TCSWYPGHLSDTHWRWVESRGPDH-DHTTGQGHFVLLDPTDPLA 625
Q Q C F+ C ++ D W V ++ P + QG ++++D +D
Sbjct: 28 QGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSD--- 84
Query: 626 WGHSAHLLSRPQVPAAP---TECLSFWYHLH---GPQIGTLRLAMR-REGEETH-LWSRS 677
H +R Q+P T C+ F Y L+ G GTL + +R +G + +W+ +
Sbjct: 85 --HDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVT 142
Query: 678 GTQGNRWHEAWATLS-HQPGSHAQYQLLFEG-LRDGYHGTMALDDVAVRPGPC 728
G G W A +S P +YQ++FE + G G +A+DD+ V PC
Sbjct: 143 GFTGRDWLRAELAVSTFWPN---EYQVIFEAEVSGGRSGYIAIDDIQVLSYPC 192
Score = 40.4 bits (93), Expect = 0.010
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 772 ETAQGHYMVVDTSP-DALPRGQTASLTSKEHRPLAQPACLTF---WYHGSLRSPGTLRVY 827
E QG YM+VD+S D + + T KE+ C+ F Y +PGTL +
Sbjct: 71 EMPQGSYMIVDSSDHDPGEKARLQLPTMKEN----DTHCIDFSYLLYSQKGLNPGTLNIL 126
Query: 828 LE-ERG--RHQVLSLSAHGGLAWRLGSMDVQA--ERAWRVVFEAVAAGVAHSYVALDDLL 882
+ +G + + +++ G W + V ++V+FEA +G Y+A+DD+
Sbjct: 127 VRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQ 186
Query: 883 LQDGPC 888
+ PC
Sbjct: 187 VLSYPC 192
Score = 37.7 bits (86), Expect = 0.063
Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 25/162 (15%)
Query: 63 PFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDL--GWYMAVGTHRG 120
P ACD+ QD + W+ A H L ++ G YM V +
Sbjct: 42 PGACDYHQD-------LYDDFEWVHVSA---------QEPHYLPPEMPQGSYMIVDSSDH 85
Query: 121 KEASTAALRSPTLREAASSC----KLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPW 176
A L+ PT++E + C L + + V + G +W TG
Sbjct: 86 DPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFT 145
Query: 177 GPGW--QELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLE 216
G W ELAV+T +++V F A + G +A+DD++
Sbjct: 146 GRDWLRAELAVST-FWPNEYQVIFEAEVSGGRSGYIAIDDIQ 186
>gi|18860902 protein tyrosine phosphatase, receptor type, K isoform b
[Homo sapiens]
Length = 1440
Score = 51.6 bits (122), Expect = 4e-06
Identities = 51/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 865 EAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWD------W 918
+ AA ++VAL LLL P F +G C + PG Y D W
Sbjct: 2 DTTAAAALPAFVAL--LLLSPWPLLGSAQGQFSAGGCTFDD--GPGACDYHQDLYDDFEW 57
Query: 919 GGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYH 978
+ + PP G + ++ PG +A L+ + C+ F Y
Sbjct: 58 VHVSAQEPHYLPPE-----MPQGSYMIVDSSDHDPGEKAR-LQLPTMKENDTHCIDFSYL 111
Query: 979 MGFPEHFYKGELKVLLHSAQGQLA--VWGAGGHRRHQWLEAQVEVAS--AKEFQIVFEAT 1034
+ + G L +L+ +G LA +W G WL A++ V++ E+Q++FEA
Sbjct: 112 LYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAE 171
Query: 1035 LGGQPALGPIALDDVEYLA 1053
+ G + G IA+DD++ L+
Sbjct: 172 VSGGRS-GYIAIDDIQVLS 189
Score = 46.6 bits (109), Expect = 1e-04
Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 21/173 (12%)
Query: 569 QSQPREVSCNFERD--TCSWYPGHLSDTHWRWVESRGPDH-DHTTGQGHFVLLDPTDPLA 625
Q Q C F+ C ++ D W V ++ P + QG ++++D +D
Sbjct: 28 QGQFSAGGCTFDDGPGACDYHQDLYDDFEWVHVSAQEPHYLPPEMPQGSYMIVDSSD--- 84
Query: 626 WGHSAHLLSRPQVPAAP---TECLSFWYHLH---GPQIGTLRLAMR-REGEETH-LWSRS 677
H +R Q+P T C+ F Y L+ G GTL + +R +G + +W+ +
Sbjct: 85 --HDPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVT 142
Query: 678 GTQGNRWHEAWATLS-HQPGSHAQYQLLFEG-LRDGYHGTMALDDVAVRPGPC 728
G G W A +S P +YQ++FE + G G +A+DD+ V PC
Sbjct: 143 GFTGRDWLRAELAVSTFWPN---EYQVIFEAEVSGGRSGYIAIDDIQVLSYPC 192
Score = 40.4 bits (93), Expect = 0.010
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 13/126 (10%)
Query: 772 ETAQGHYMVVDTSP-DALPRGQTASLTSKEHRPLAQPACLTF---WYHGSLRSPGTLRVY 827
E QG YM+VD+S D + + T KE+ C+ F Y +PGTL +
Sbjct: 71 EMPQGSYMIVDSSDHDPGEKARLQLPTMKEN----DTHCIDFSYLLYSQKGLNPGTLNIL 126
Query: 828 LE-ERG--RHQVLSLSAHGGLAWRLGSMDVQA--ERAWRVVFEAVAAGVAHSYVALDDLL 882
+ +G + + +++ G W + V ++V+FEA +G Y+A+DD+
Sbjct: 127 VRVNKGPLANPIWNVTGFTGRDWLRAELAVSTFWPNEYQVIFEAEVSGGRSGYIAIDDIQ 186
Query: 883 LQDGPC 888
+ PC
Sbjct: 187 VLSYPC 192
Score = 37.7 bits (86), Expect = 0.063
Identities = 40/162 (24%), Positives = 63/162 (38%), Gaps = 25/162 (15%)
Query: 63 PFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDL--GWYMAVGTHRG 120
P ACD+ QD + W+ A H L ++ G YM V +
Sbjct: 42 PGACDYHQD-------LYDDFEWVHVSA---------QEPHYLPPEMPQGSYMIVDSSDH 85
Query: 121 KEASTAALRSPTLREAASSC----KLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPW 176
A L+ PT++E + C L + + V + G +W TG
Sbjct: 86 DPGEKARLQLPTMKENDTHCIDFSYLLYSQKGLNPGTLNILVRVNKGPLANPIWNVTGFT 145
Query: 177 GPGW--QELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLE 216
G W ELAV+T +++V F A + G +A+DD++
Sbjct: 146 GRDWLRAELAVST-FWPNEYQVIFEAEVSGGRSGYIAIDDIQ 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,170,331
Number of Sequences: 37866
Number of extensions: 3210421
Number of successful extensions: 13731
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 12423
Number of HSP's gapped (non-prelim): 1110
length of query: 1137
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1024
effective length of database: 13,968,660
effective search space: 14303907840
effective search space used: 14303907840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.