Guide to the Human Genome
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Search of human proteins with 118722347

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118722347 over-expressed breast tumor protein [Homo sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118722347 over-expressed breast tumor protein [Homo sapiens]       824   0.0  
gi|222136684 prickle homolog 1 [Homo sapiens]                         222   4e-58
gi|222136682 prickle homolog 1 [Homo sapiens]                         222   4e-58
gi|222136680 prickle homolog 1 [Homo sapiens]                         222   4e-58
gi|222136678 prickle homolog 1 [Homo sapiens]                         222   4e-58
gi|38524620 prickle-like 2 [Homo sapiens]                             219   2e-57
gi|7710129 LIM domain only 6 [Homo sapiens]                           216   4e-56
gi|7661666 testin isoform 1 [Homo sapiens]                            142   7e-34
gi|23238188 testin isoform 2 [Homo sapiens]                           142   7e-34
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]             133   2e-31
gi|54112385 four and a half LIM domains 3 [Homo sapiens]               74   2e-13
gi|170932518 paxillin isoform 3 [Homo sapiens]                         74   3e-13
gi|170932516 paxillin isoform 2 [Homo sapiens]                         74   3e-13
gi|170932514 paxillin isoform 1 [Homo sapiens]                         74   3e-13
gi|109638745 transforming growth factor beta 1 induced transcrip...    68   2e-11
gi|21361591 transforming growth factor beta 1 induced transcript...    68   2e-11
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]    63   5e-10
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]    63   5e-10
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]    63   5e-10
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]    63   5e-10
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]    63   5e-10
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]    63   5e-10
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]     63   5e-10
gi|30410801 activator of cAMP-responsive element modulator (CREM...    62   7e-10
gi|87159836 four and a half LIM domains 2 [Homo sapiens]               62   9e-10
gi|87159834 four and a half LIM domains 2 [Homo sapiens]               62   9e-10
gi|42403575 four and a half LIM domains 2 [Homo sapiens]               62   9e-10
gi|87159832 four and a half LIM domains 2 [Homo sapiens]               62   9e-10
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]             61   1e-09
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]              61   1e-09

>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
          Length = 384

 Score =  824 bits (2128), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MSVQNSGWPHQEDSPKPQDPGPPANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQ 60
           MSVQNSGWPHQEDSPKPQDPGPPANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQ
Sbjct: 1   MSVQNSGWPHQEDSPKPQDPGPPANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQ 60

Query: 61  APNWTGLQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLE 120
           APNWTGLQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLE
Sbjct: 61  APNWTGLQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLE 120

Query: 121 GHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRH 180
           GHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRH
Sbjct: 121 GHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRH 180

Query: 181 HAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSC 240
           HAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSC
Sbjct: 181 HAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSC 240

Query: 241 FENRYSDAGSSWAGALEGQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAGGSSLQTQR 300
           FENRYSDAGSSWAGALEGQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAGGSSLQTQR
Sbjct: 241 FENRYSDAGSSWAGALEGQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAGGSSLQTQR 300

Query: 301 GLPGSSPQQENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDSEPEGFFLGERLP 360
           GLPGSSPQQENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDSEPEGFFLGERLP
Sbjct: 301 GLPGSSPQQENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDSEPEGFFLGERLP 360

Query: 361 QSWKTPGSLQAEDSNASKTHCTMC 384
           QSWKTPGSLQAEDSNASKTHCTMC
Sbjct: 361 QSWKTPGSLQAEDSNASKTHCTMC 384


>gi|222136684 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score =  222 bits (566), Expect = 4e-58
 Identities = 108/230 (46%), Positives = 142/230 (61%), Gaps = 6/230 (2%)

Query: 24  ANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQ 77
           + SD DSG    E         P  + L   CL   + P  N  G    ++ LL QLPP 
Sbjct: 20  STSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPH 79

Query: 78  DIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYG 137
           D + RYC +L EEE+ ELQ+F A+RK+EALG+G  +L+   +    CE+C   +  GE  
Sbjct: 80  DNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVA 139

Query: 138 VFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIF 197
           VFA+RAG   CWH  CF C  C + L++LIYFY DG+++CGRHHAELL+PRC ACD++IF
Sbjct: 140 VFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF 199

Query: 198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           +  CTEAEG+ WH  HFCC +C   LGG RY +  G P C  CFE+ Y++
Sbjct: 200 ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAE 249



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/133 (26%), Positives = 45/133 (33%), Gaps = 13/133 (9%)

Query: 108 GQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLI 167
           G+  A L+ P+     C  C E++   E         E R WH   F C  C   L    
Sbjct: 180 GRHHAELLKPR-----CSACDEIIFADE-----CTEAEGRHWHMKHFCCLECETVLGGQR 229

Query: 168 YFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHENHFC--CQDCAGPLG 224
           Y   DG+ +C      L    C  C + I         +GQ WH    C  C  C   L 
Sbjct: 230 YIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLL 289

Query: 225 GGRYALPGGSPCC 237
           G  +    G   C
Sbjct: 290 GCPFLPKQGQIYC 302



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 16/26 (61%), Positives = 21/26 (80%)

Query: 336 DTPFSTCSSSSDSEPEGFFLGERLPQ 361
           D+  S+ SSSSDSE EG+FLG+ +PQ
Sbjct: 760 DSWCSSSSSSSDSEEEGYFLGQPIPQ 785



 Score = 32.0 bits (71), Expect = 0.96
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 124 CEKCRELLKPGEYGV-FAARAGEQRCWH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
           CE C E +     GV  A    + + WH  + CF+C  C  +L+   +    GQ+YC +
Sbjct: 251 CETCGEHI-----GVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304


>gi|222136682 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score =  222 bits (566), Expect = 4e-58
 Identities = 108/230 (46%), Positives = 142/230 (61%), Gaps = 6/230 (2%)

Query: 24  ANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQ 77
           + SD DSG    E         P  + L   CL   + P  N  G    ++ LL QLPP 
Sbjct: 20  STSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPH 79

Query: 78  DIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYG 137
           D + RYC +L EEE+ ELQ+F A+RK+EALG+G  +L+   +    CE+C   +  GE  
Sbjct: 80  DNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVA 139

Query: 138 VFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIF 197
           VFA+RAG   CWH  CF C  C + L++LIYFY DG+++CGRHHAELL+PRC ACD++IF
Sbjct: 140 VFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF 199

Query: 198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           +  CTEAEG+ WH  HFCC +C   LGG RY +  G P C  CFE+ Y++
Sbjct: 200 ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAE 249



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/133 (26%), Positives = 45/133 (33%), Gaps = 13/133 (9%)

Query: 108 GQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLI 167
           G+  A L+ P+     C  C E++   E         E R WH   F C  C   L    
Sbjct: 180 GRHHAELLKPR-----CSACDEIIFADE-----CTEAEGRHWHMKHFCCLECETVLGGQR 229

Query: 168 YFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHENHFC--CQDCAGPLG 224
           Y   DG+ +C      L    C  C + I         +GQ WH    C  C  C   L 
Sbjct: 230 YIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLL 289

Query: 225 GGRYALPGGSPCC 237
           G  +    G   C
Sbjct: 290 GCPFLPKQGQIYC 302



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 16/26 (61%), Positives = 21/26 (80%)

Query: 336 DTPFSTCSSSSDSEPEGFFLGERLPQ 361
           D+  S+ SSSSDSE EG+FLG+ +PQ
Sbjct: 760 DSWCSSSSSSSDSEEEGYFLGQPIPQ 785



 Score = 32.0 bits (71), Expect = 0.96
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 124 CEKCRELLKPGEYGV-FAARAGEQRCWH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
           CE C E +     GV  A    + + WH  + CF+C  C  +L+   +    GQ+YC +
Sbjct: 251 CETCGEHI-----GVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304


>gi|222136680 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score =  222 bits (566), Expect = 4e-58
 Identities = 108/230 (46%), Positives = 142/230 (61%), Gaps = 6/230 (2%)

Query: 24  ANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQ 77
           + SD DSG    E         P  + L   CL   + P  N  G    ++ LL QLPP 
Sbjct: 20  STSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPH 79

Query: 78  DIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYG 137
           D + RYC +L EEE+ ELQ+F A+RK+EALG+G  +L+   +    CE+C   +  GE  
Sbjct: 80  DNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVA 139

Query: 138 VFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIF 197
           VFA+RAG   CWH  CF C  C + L++LIYFY DG+++CGRHHAELL+PRC ACD++IF
Sbjct: 140 VFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF 199

Query: 198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           +  CTEAEG+ WH  HFCC +C   LGG RY +  G P C  CFE+ Y++
Sbjct: 200 ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAE 249



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/133 (26%), Positives = 45/133 (33%), Gaps = 13/133 (9%)

Query: 108 GQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLI 167
           G+  A L+ P+     C  C E++   E         E R WH   F C  C   L    
Sbjct: 180 GRHHAELLKPR-----CSACDEIIFADE-----CTEAEGRHWHMKHFCCLECETVLGGQR 229

Query: 168 YFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHENHFC--CQDCAGPLG 224
           Y   DG+ +C      L    C  C + I         +GQ WH    C  C  C   L 
Sbjct: 230 YIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLL 289

Query: 225 GGRYALPGGSPCC 237
           G  +    G   C
Sbjct: 290 GCPFLPKQGQIYC 302



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 16/26 (61%), Positives = 21/26 (80%)

Query: 336 DTPFSTCSSSSDSEPEGFFLGERLPQ 361
           D+  S+ SSSSDSE EG+FLG+ +PQ
Sbjct: 760 DSWCSSSSSSSDSEEEGYFLGQPIPQ 785



 Score = 32.0 bits (71), Expect = 0.96
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 124 CEKCRELLKPGEYGV-FAARAGEQRCWH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
           CE C E +     GV  A    + + WH  + CF+C  C  +L+   +    GQ+YC +
Sbjct: 251 CETCGEHI-----GVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304


>gi|222136678 prickle homolog 1 [Homo sapiens]
          Length = 831

 Score =  222 bits (566), Expect = 4e-58
 Identities = 108/230 (46%), Positives = 142/230 (61%), Gaps = 6/230 (2%)

Query: 24  ANSDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQ 77
           + SD DSG    E         P  + L   CL   + P  N  G    ++ LL QLPP 
Sbjct: 20  STSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPH 79

Query: 78  DIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYG 137
           D + RYC +L EEE+ ELQ+F A+RK+EALG+G  +L+   +    CE+C   +  GE  
Sbjct: 80  DNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAVMHAVCEQCGLKINGGEVA 139

Query: 138 VFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIF 197
           VFA+RAG   CWH  CF C  C + L++LIYFY DG+++CGRHHAELL+PRC ACD++IF
Sbjct: 140 VFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIF 199

Query: 198 SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           +  CTEAEG+ WH  HFCC +C   LGG RY +  G P C  CFE+ Y++
Sbjct: 200 ADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAE 249



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/133 (26%), Positives = 45/133 (33%), Gaps = 13/133 (9%)

Query: 108 GQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLI 167
           G+  A L+ P+     C  C E++   E         E R WH   F C  C   L    
Sbjct: 180 GRHHAELLKPR-----CSACDEIIFADE-----CTEAEGRHWHMKHFCCLECETVLGGQR 229

Query: 168 YFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHENHFC--CQDCAGPLG 224
           Y   DG+ +C      L    C  C + I         +GQ WH    C  C  C   L 
Sbjct: 230 YIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLL 289

Query: 225 GGRYALPGGSPCC 237
           G  +    G   C
Sbjct: 290 GCPFLPKQGQIYC 302



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 16/26 (61%), Positives = 21/26 (80%)

Query: 336 DTPFSTCSSSSDSEPEGFFLGERLPQ 361
           D+  S+ SSSSDSE EG+FLG+ +PQ
Sbjct: 760 DSWCSSSSSSSDSEEEGYFLGQPIPQ 785



 Score = 32.0 bits (71), Expect = 0.96
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 124 CEKCRELLKPGEYGV-FAARAGEQRCWH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
           CE C E +     GV  A    + + WH  + CF+C  C  +L+   +    GQ+YC +
Sbjct: 251 CETCGEHI-----GVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304


>gi|38524620 prickle-like 2 [Homo sapiens]
          Length = 844

 Score =  219 bits (559), Expect = 2e-57
 Identities = 109/238 (45%), Positives = 141/238 (59%), Gaps = 22/238 (9%)

Query: 24  ANSDSDSGHL--------PGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQT 69
           + SD DSG          PG  PE  H            CL   + P  N  G    ++ 
Sbjct: 24  STSDDDSGCALEEYAWVPPGLKPEQVHQYYS--------CLPEEKVPYVNSPGEKLRIKQ 75

Query: 70  LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRE 129
           LL QLPP D + RYC +L EEE+ EL+LF ++RK+E LG+G  R     + G  CE+C  
Sbjct: 76  LLHQLPPHDNEVRYCNSLDEEEKRELKLFSSQRKRENLGRGNVRPFPVTMTGAICEQCGG 135

Query: 130 LLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRC 189
            +  G+  VFA+RAG   CWH PCF C  C + L++LIYFY DG++YCGRHHAE L+PRC
Sbjct: 136 QINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCGRHHAECLKPRC 195

Query: 190 PACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
            ACD++IF+  CTEAEG+ WH  HFCC +C   LGG RY +  G P C  CFE+ Y++
Sbjct: 196 AACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCCHCFESLYAE 253



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 16/22 (72%), Positives = 20/22 (90%)

Query: 340 STCSSSSDSEPEGFFLGERLPQ 361
           STCSSSS+S+ EG+FLGE +PQ
Sbjct: 776 STCSSSSESDNEGYFLGEPIPQ 797



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 11/33 (33%), Positives = 18/33 (54%), Gaps = 2/33 (6%)

Query: 149 WH--QPCFACQACGQALINLIYFYHDGQLYCGR 179
           WH  + CF C  C ++L+   +    GQ++C R
Sbjct: 276 WHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308


>gi|7710129 LIM domain only 6 [Homo sapiens]
          Length = 615

 Score =  216 bits (549), Expect = 4e-56
 Identities = 109/243 (44%), Positives = 143/243 (58%), Gaps = 9/243 (3%)

Query: 26  SDSDSGHLPGEDPEDTHAQGPAVLSLGSLCLDTNQAP--NWTG----LQTLLQQLPPQDI 79
           SD DSG    E         P  +     CL  ++ P  N  G    ++ LL QLPP D 
Sbjct: 82  SDDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKVPYVNSPGEKYRIKQLLHQLPPHDS 141

Query: 80  DERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYGVF 139
           + +YC AL EEE+ EL+ F  +RK+E LG+G+ R+    + G  CE+C + +  G+  VF
Sbjct: 142 EAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRIFPVTITGAICEECGKQIGGGDIAVF 201

Query: 140 AARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSW 199
           A+RAG   CWH  CF C  C + L++LIYFYH G++YCGRHHAE LRPRC ACD++IFS 
Sbjct: 202 ASRAGLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSP 261

Query: 200 RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR---YSDAGSSWAGAL 256
            CTEAEG+ WH +HFCC +C   LGG RY +    P C +C+E R   Y D      G  
Sbjct: 262 ECTEAEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHAEYCDGCGEHIGLD 321

Query: 257 EGQ 259
           +GQ
Sbjct: 322 QGQ 324



 Score = 35.4 bits (80), Expect = 0.087
 Identities = 63/249 (25%), Positives = 90/249 (36%), Gaps = 36/249 (14%)

Query: 143 AGEQRCWHQP--CFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWR 200
           A E + WH    CF C  CG+AL+   +    G ++C R  +    P  P   +  +S  
Sbjct: 326 AYEGQHWHASDRCFCCSRCGRALLGRPFLPRRGLIFCSRACSLGSEPTAPGPSRRSWSAG 385

Query: 201 CTEAEGQRWHENHFCCQDCAGPL--GGGRYALPGGSPCCPSCF----ENRYSDAGSSWAG 254
              A       +    +  +     G      P   P  PS F     +R+S        
Sbjct: 386 PVTAPLAASTASFSAVKGASETTTKGTSTELAPATGPEEPSRFLRGAPHRHSMPELGLRS 445

Query: 255 ALE------GQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAGG-----SSLQTQRGLP 303
             E      GQ  L     D   GR  T   S    R  L + GG     S+   QR  P
Sbjct: 446 VPEPPPESPGQPNLRPD--DSAFGRQSTPRVSF---RDPLVSEGGPRRTLSAPPAQRRRP 500

Query: 304 GSSPQQ-----------ENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDS-EPE 351
            S P +            +   ++  + +   QC   +  D +    S  SSSS+S E +
Sbjct: 501 RSPPPRAPSRRRHHHHNHHHHHNRHPSRRRHYQCDAGSGSDSESCSSSPSSSSSESSEDD 560

Query: 352 GFFLGERLP 360
           GFFLGER+P
Sbjct: 561 GFFLGERIP 569


>gi|7661666 testin isoform 1 [Homo sapiens]
          Length = 421

 Score =  142 bits (357), Expect = 7e-34
 Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 32/209 (15%)

Query: 70  LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALG------------QGVARLVLP 117
           L +QLP  D D   C  L   E  E++ F  + K EALG            QG  ++ +P
Sbjct: 150 LAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIP 209

Query: 118 --------------------KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQ 157
                               K   ++C  C+  +K G+  ++A RAG  + WH  CF C 
Sbjct: 210 GGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCS 269

Query: 158 ACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQ 217
            C + L+++IYF+ + +LYCGRH+ +  +PRC  CD+LIFS   T+AE Q WH  HFCC 
Sbjct: 270 TCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCF 329

Query: 218 DCAGPLGGGRYALPGGSPCCPSCFENRYS 246
           DC   L G  Y +    P C  C+   ++
Sbjct: 330 DCDSILAGEIYVMVNDKPVCKPCYVKNHA 358


>gi|23238188 testin isoform 2 [Homo sapiens]
          Length = 412

 Score =  142 bits (357), Expect = 7e-34
 Identities = 71/209 (33%), Positives = 102/209 (48%), Gaps = 32/209 (15%)

Query: 70  LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALG------------QGVARLVLP 117
           L +QLP  D D   C  L   E  E++ F  + K EALG            QG  ++ +P
Sbjct: 141 LAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIP 200

Query: 118 --------------------KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQ 157
                               K   ++C  C+  +K G+  ++A RAG  + WH  CF C 
Sbjct: 201 GGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCS 260

Query: 158 ACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQ 217
            C + L+++IYF+ + +LYCGRH+ +  +PRC  CD+LIFS   T+AE Q WH  HFCC 
Sbjct: 261 TCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCF 320

Query: 218 DCAGPLGGGRYALPGGSPCCPSCFENRYS 246
           DC   L G  Y +    P C  C+   ++
Sbjct: 321 DCDSILAGEIYVMVNDKPVCKPCYVKNHA 349


>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
          Length = 365

 Score =  133 bits (335), Expect = 2e-31
 Identities = 73/209 (34%), Positives = 97/209 (46%), Gaps = 32/209 (15%)

Query: 70  LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLV----LPKLEG---- 121
           L+ QLP  D D   C  L E E   ++ F  + K EALG G   L     LPK EG    
Sbjct: 157 LMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQE 216

Query: 122 ------------------------HTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQ 157
                                   + CE C+    P    V++ RAG  + WH  CF C 
Sbjct: 217 KPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCA 276

Query: 158 ACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQ 217
            C + L++LIYF+ DG  +CGRH+ E LRPRC  CD++IF+      E   WH  HF C+
Sbjct: 277 KCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCE 336

Query: 218 DCAGPLGGGRYALPGGSPCCPSCFENRYS 246
            C   L G  Y +  G   CP+C +++ S
Sbjct: 337 GCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 37/126 (29%), Positives = 61/126 (48%), Gaps = 5/126 (3%)

Query: 122 HTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHH 181
           +TC +C++L+      +F     E R +H+ CF C  C ++L +  +   D +L C   +
Sbjct: 38  NTCAECQQLIGHDSRELFY----EDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCY 93

Query: 182 AELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSC 240
                 +C AC + +    R  E  GQ WHE+ F C  C  PLG   +    G+  C  C
Sbjct: 94  CSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPC 153

Query: 241 FENRYS 246
           +EN+++
Sbjct: 154 YENKFA 159



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 38/132 (28%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 124 CEKCRELLKPG----EYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGR 179
           C  C E + PG    EYG         + WH+ CF C  C Q L +  +    G  YC  
Sbjct: 101 CSACGETVMPGSRKLEYG--------GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVP 152

Query: 180 HHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPS 239
            +     PRC  C + +     T  + Q WH     C  C  PL G ++      P C +
Sbjct: 153 CYENKFAPRCARCSKTLTQGGVTYRD-QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVA 211

Query: 240 CFENRYSDAGSS 251
           CF   ++   SS
Sbjct: 212 CFGELFAPKCSS 223



 Score = 55.8 bits (133), Expect = 6e-08
 Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 9/120 (7%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C +C + L  G  GV        + WH+ C  C  C   L    +   D   YC     E
Sbjct: 162 CARCSKTLTQG--GV----TYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGE 215

Query: 184 LLRPRCPACDQLIF---SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSC 240
           L  P+C +C + I      +    E + WH N F C  C+  L G  +   G    C  C
Sbjct: 216 LFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGC 275



 Score = 36.6 bits (83), Expect = 0.039
 Identities = 25/99 (25%), Positives = 35/99 (35%), Gaps = 1/99 (1%)

Query: 154 FACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHEN 212
           F C  C ++L    Y   D   YC   +       C  C QLI    R    E + +HE 
Sbjct: 5   FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSDAGSS 251
            F C  C   L    +        C  C+ + +S   S+
Sbjct: 65  CFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSA 103


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH  CF C+ C    +N  +F HDGQ YC  H+ E     C  C + I + RC  A  ++
Sbjct: 328 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 386

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
           +H  HF C  C   L  G +      P C +CF
Sbjct: 387 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 419



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 1/91 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           + WH   F C  C + + +  +F  DGQ YC + +  L  PRC  C+  I   +   A  
Sbjct: 208 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD-KVVTALD 266

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
           + WH  HF C  C    G   +    G   C
Sbjct: 267 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 297



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 1/98 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           R WH   F C  CG       +   DG+ YC + + ++  P+C  C + I       A  
Sbjct: 267 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILE-NYISALN 325

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR 244
             WH   F C++C  P   G +    G P C   +  R
Sbjct: 326 TLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 363



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 4/82 (4%)

Query: 189 CPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSDA 248
           C AC + I + +   A G+ WH  HF C  C   +G   +    G P C   + N +S  
Sbjct: 191 CGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 249

Query: 249 GSSWAGALEGQAFLGETGLDRT 270
                G +  +     T LDRT
Sbjct: 250 CYYCNGPILDKVV---TALDRT 268


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH  CF C+ C    +N  +F HDGQ YC  H+ E     C  C + I + RC  A  ++
Sbjct: 461 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 519

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
           +H  HF C  C   L  G +      P C +CF
Sbjct: 520 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 552



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 1/91 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           + WH   F C  C + + +  +F  DGQ YC + +  L  PRC  C+  I   +   A  
Sbjct: 341 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD-KVVTALD 399

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
           + WH  HF C  C    G   +    G   C
Sbjct: 400 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 430



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 1/98 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           R WH   F C  CG       +   DG+ YC + + ++  P+C  C + I       A  
Sbjct: 400 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILE-NYISALN 458

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR 244
             WH   F C++C  P   G +    G P C   +  R
Sbjct: 459 TLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 496



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 4/82 (4%)

Query: 189 CPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSDA 248
           C AC + I + +   A G+ WH  HF C  C   +G   +    G P C   + N +S  
Sbjct: 324 CGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 382

Query: 249 GSSWAGALEGQAFLGETGLDRT 270
                G +  +     T LDRT
Sbjct: 383 CYYCNGPILDKVV---TALDRT 401


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 33/93 (35%), Positives = 44/93 (47%), Gaps = 1/93 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH  CF C+ C    +N  +F HDGQ YC  H+ E     C  C + I + RC  A  ++
Sbjct: 495 WHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPI-TGRCITAMAKK 553

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
           +H  HF C  C   L  G +      P C +CF
Sbjct: 554 FHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCF 586



 Score = 55.5 bits (132), Expect = 8e-08
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 1/91 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           + WH   F C  C + + +  +F  DGQ YC + +  L  PRC  C+  I   +   A  
Sbjct: 375 KTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILD-KVVTALD 433

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
           + WH  HF C  C    G   +    G   C
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYC 464



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 1/98 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           R WH   F C  CG       +   DG+ YC + + ++  P+C  C + I       A  
Sbjct: 434 RTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILE-NYISALN 492

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR 244
             WH   F C++C  P   G +    G P C   +  R
Sbjct: 493 TLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHER 530



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 24/82 (29%), Positives = 34/82 (41%), Gaps = 4/82 (4%)

Query: 189 CPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSDA 248
           C AC + I + +   A G+ WH  HF C  C   +G   +    G P C   + N +S  
Sbjct: 358 CGACKKPI-AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416

Query: 249 GSSWAGALEGQAFLGETGLDRT 270
                G +  +     T LDRT
Sbjct: 417 CYYCNGPILDKVV---TALDRT 435


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH  CF C+ C        +F H+G+  C  H        C  C  L  + RC  A G+R
Sbjct: 365 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRR 423

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
           +H +HF C  C  PL  G +    G P C  CF
Sbjct: 424 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 456



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 33/91 (36%), Positives = 39/91 (42%), Gaps = 1/91 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           R WH   F C  C  AL    +F  DG  +C   + E   PRC  C+Q I   +   A G
Sbjct: 245 RAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPI-RHKMVTALG 303

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
             WH  HFCC  C  P G   +    G P C
Sbjct: 304 THWHPEHFCCVSCGEPFGDEGFHEREGRPYC 334



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 1/96 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH   F C +CG+   +  +   +G+ YC R   +L  PRC  C   I       A    
Sbjct: 306 WHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILD-NYISALSAL 364

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR 244
           WH + F C++C  P  GG +    G P C + F  R
Sbjct: 365 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHAR 400



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 189 CPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
           C +C++ I + +   A G+ WH  HF C  C+  LGG  +    G+P CP C+  R+S
Sbjct: 228 CGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 284


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 32/93 (34%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH  CF C+ C        +F H+G+  C  H        C  C  L  + RC  A G+R
Sbjct: 348 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCG-LPVTGRCVSALGRR 406

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
           +H +HF C  C  PL  G +    G P C  CF
Sbjct: 407 FHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCF 439



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 33/91 (36%), Positives = 39/91 (42%), Gaps = 1/91 (1%)

Query: 147 RCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEG 206
           R WH   F C  C  AL    +F  DG  +C   + E   PRC  C+Q I   +   A G
Sbjct: 228 RAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPI-RHKMVTALG 286

Query: 207 QRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
             WH  HFCC  C  P G   +    G P C
Sbjct: 287 THWHPEHFCCVSCGEPFGDEGFHEREGRPYC 317



 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 1/96 (1%)

Query: 149 WHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQR 208
           WH   F C +CG+   +  +   +G+ YC R   +L  PRC  C   I       A    
Sbjct: 289 WHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILD-NYISALSAL 347

Query: 209 WHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENR 244
           WH + F C++C  P  GG +    G P C + F  R
Sbjct: 348 WHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHAR 383



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 1/58 (1%)

Query: 189 CPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
           C +C++ I + +   A G+ WH  HF C  C+  LGG  +    G+P CP C+  R+S
Sbjct: 211 CGSCNKPI-AGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFS 267


>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
          Length = 194

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 34  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 89

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 90  NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 150 CVTCHETKFA 159



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 17/71 (23%), Positives = 27/71 (38%), Gaps = 4/71 (5%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 101 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156

Query: 184 LLRPRCPACDQ 194
                C  C++
Sbjct: 157 KFAKHCVKCNK 167



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 33


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 34  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 89

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 90  NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 150 CVTCHETKFA 159



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 101 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C++ I S   T  + Q WH + F C  C+  L G R+        C  C++N
Sbjct: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C KC + +  G  G+      + + WH  CF C  C + L    +   + Q YC   +  
Sbjct: 162 CVKCNKAITSG--GI----TYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215

Query: 184 LLRPRCPACDQLIFSW----RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPS 239
            +  +C  C   I  +         EGQ WH+  F C+ C+  L   R+        CP 
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275

Query: 240 C 240
           C
Sbjct: 276 C 276



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 33


>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 34  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 89

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 90  NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 150 CVTCHETKFA 159



 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 52/229 (22%), Positives = 85/229 (37%), Gaps = 8/229 (3%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 101 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C++ I S   T  + Q WH + F C  C+  L G R+        C  C++N
Sbjct: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215

Query: 244 RYSDAGSSWAGALEGQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAG--GSSLQTQRG 301
             +   +     + G+  +       ++ R     +   L  TL  +A   G     +R 
Sbjct: 216 FVAKKCAGCKNPITGKRTVSRVSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERT 275

Query: 302 LPGSSPQQENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDSEP 350
            P S      R      AP+G    +       KD P +T +S++ + P
Sbjct: 276 CP-SWVVVLYRKNRSLAAPRGPGLVKAPVWWPMKDNPGTTTASTAKNAP 323



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 33


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 34  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 89

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 90  NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 150 CVTCHETKFA 159



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 101 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C++ I S   T  + Q WH + F C  C+  L G R+        C  C++N
Sbjct: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C KC + +  G  G+      + + WH  CF C  C + L    +   + Q YC   +  
Sbjct: 162 CVKCNKAITSG--GI----TYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215

Query: 184 LLRPRCPACDQLIFSW----RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPS 239
            +  +C  C   I  +         EGQ WH+  F C+ C+  L   R+        CP 
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275

Query: 240 C 240
           C
Sbjct: 276 C 276



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 33


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 63  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 118

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 119 NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 178

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 179 CVTCHETKFA 188



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 130 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 185

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C++ I S   T  + Q WH + F C  C+  L G R+        C  C++N
Sbjct: 186 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 244



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C KC + +  G  G+      + + WH  CF C  C + L    +   + Q YC   +  
Sbjct: 191 CVKCNKAITSG--GI----TYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 244

Query: 184 LLRPRCPACDQLIFSW----RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPS 239
            +  +C  C   I  +         EGQ WH+  F C+ C+  L   R+        CP 
Sbjct: 245 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 304

Query: 240 C 240
           C
Sbjct: 305 C 305



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 34  FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 62


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 50  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 105

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 106 NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 165

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 166 CVTCHETKFA 175



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 117 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 172

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C++ I S   T  + Q WH + F C  C+  L G R+        C  C++N
Sbjct: 173 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 231



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C KC + +  G  G+      + + WH  CF C  C + L    +   + Q YC   +  
Sbjct: 178 CVKCNKAITSG--GI----TYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 231

Query: 184 LLRPRCPACDQLIFSW----RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPS 239
            +  +C  C   I  +         EGQ WH+  F C+ C+  L   R+        CP 
Sbjct: 232 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 291

Query: 240 C 240
           C
Sbjct: 292 C 292



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 21  FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 49


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 5/130 (3%)

Query: 118 KLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYC 177
           K   +TC +CR+ +      V      + R WH  CF C  C   L N  +   D ++ C
Sbjct: 34  KFCANTCVECRKPIGADSKEVHY----KNRFWHDTCFRCAKCLHPLANETFVAKDNKILC 89

Query: 178 GRHHAELLRPRCPACDQLIFSW-RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPC 236
            +       P+C  C + I +  +  E +G  WH++ F C +C   +G G +   G    
Sbjct: 90  NKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFY 149

Query: 237 CPSCFENRYS 246
           C +C E +++
Sbjct: 150 CVTCHETKFA 159



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 5/120 (4%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C+ C + +  G+  V      +   WH+ CF C  C Q +    +F      YC   H  
Sbjct: 101 CKGCFKAIVAGDQNV----EYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHET 156

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C++ I S   T  + Q WH + F C  C+  L G R+        C  C++N
Sbjct: 157 KFAKHCVKCNKAITSGGIT-YQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C KC + +  G  G+      + + WH  CF C  C + L    +   + Q YC   +  
Sbjct: 162 CVKCNKAITSG--GI----TYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215

Query: 184 LLRPRCPACDQLIFSW----RCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPS 239
            +  +C  C   I  +         EGQ WH+  F C+ C+  L   R+        CP 
Sbjct: 216 FVAKKCAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPD 275

Query: 240 C 240
           C
Sbjct: 276 C 276



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 12/29 (41%), Positives = 14/29 (48%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
           F C  C  PL G +Y    G  CC  CF+
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFD 33


>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 32/124 (25%), Positives = 54/124 (43%), Gaps = 5/124 (4%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           CE+C++ ++     +      + R WH+ CF C  C  +L+   +   D +L C   ++ 
Sbjct: 41  CEECKKPIESDSKDL----CYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSN 96

Query: 184 LLRPRCPACDQLIF-SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFE 242
               +C  C + I    R  E +G  WHE  F C++C  P+G            C  CFE
Sbjct: 97  ECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFE 156

Query: 243 NRYS 246
             ++
Sbjct: 157 KEFA 160



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 34/142 (23%), Positives = 54/142 (38%), Gaps = 8/142 (5%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C  C+  + PG   +      +   WH+ CF C+ C Q +        +   YC     +
Sbjct: 102 CFHCKRTIMPGSRKM----EFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEK 157

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
                C  C ++I S   T  + Q WH+  F C  C   L   ++      P C  C+ +
Sbjct: 158 EFAHYCNFCKKVITSGGITFCD-QLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNH 216

Query: 244 RYSD---AGSSWAGALEGQAFL 262
            Y++   A S     L G  F+
Sbjct: 217 LYANKCVACSKPISGLTGAKFI 238



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 28/122 (22%), Positives = 46/122 (37%), Gaps = 9/122 (7%)

Query: 122 HTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHH 181
           H C  C++++  G  G+        + WH+ CF C  C + L    +   D   +C   +
Sbjct: 161 HYCNFCKKVITSG--GITFC----DQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCMDCY 214

Query: 182 AELLRPRCPACDQLIFSWRCTE---AEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCP 238
             L   +C AC + I      +    +  +WH   F C  C+  L G  +        C 
Sbjct: 215 NHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQ 274

Query: 239 SC 240
            C
Sbjct: 275 KC 276



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 25/94 (26%), Positives = 35/94 (37%), Gaps = 1/94 (1%)

Query: 154 FACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFS-WRCTEAEGQRWHEN 212
           F CQ C  +L+   Y   D   YC   +  +    C  C + I S  +    + + WHE 
Sbjct: 6   FYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEG 65

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
            F C  C   L    +A       C  C+ N  S
Sbjct: 66  CFKCTKCNHSLVEKPFAAKDERLLCTECYSNECS 99



 Score = 35.8 bits (81), Expect = 0.067
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           HF CQ C   L G +Y L   SP C +C++  +S+
Sbjct: 5   HFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSN 39


>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 119 LEGHTCEKCRELL----KPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQ 174
           L  +TCE+C + +    K   Y        + R WH+ CF C  C  +L++  +   + Q
Sbjct: 35  LFANTCEECGKPIGCDCKDLSY--------KDRHWHEACFHCSQCRNSLVDKPFAAKEDQ 86

Query: 175 LYCGRHHAELLRPRCPACDQLIF-SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGG 233
           L C   ++     +C  C + I    R  E +G  WHE  F C  C  P+G   +     
Sbjct: 87  LLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDN 146

Query: 234 SPCCPSCFENRYS 246
              C  C+E +++
Sbjct: 147 QNFCVPCYEKQHA 159



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQR--CWHQPCFACQACGQALINLIYFYHDGQLYCGRHH 181
           C++C++ + PG       R  E +   WH+ CF C  C Q +    +   D Q +C   +
Sbjct: 101 CQECKKTIMPG------TRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154

Query: 182 AELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
            +    +C  C + I +   T  E Q WH+  F C  C   L G R+        C +CF
Sbjct: 155 EKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 242 ENRYSDAGSSWAGALEG 258
            + Y+   +     + G
Sbjct: 214 CDLYAKKCAGCTNPISG 230



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%)

Query: 116 LPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQL 175
           +P  E     +C +  KP   G    R   ++ WH+ CF C AC + L    +   D   
Sbjct: 151 VPCYEKQHAMQCVQCKKPITTGGVTYR---EQPWHKECFVCTACRKQLSGQRFTARDDFA 207

Query: 176 YCGRHHAELLRPRCPACDQLIFSWRCTE---AEGQRWHENHFCCQDCAGPLGGGRYALPG 232
           YC     +L   +C  C   I     T+    E ++WH + F C+ C+  L G  +    
Sbjct: 208 YCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTER 267

Query: 233 GSPCCPSC 240
               CP C
Sbjct: 268 DDILCPDC 275



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/94 (25%), Positives = 33/94 (35%), Gaps = 1/94 (1%)

Query: 154 FACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHEN 212
           F C  C ++L    Y   +   YC      L    C  C + I    +    + + WHE 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
            F C  C   L    +A       C  C+ N YS
Sbjct: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           F C  C   L G +Y L   SP C  CFE  +++
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFAN 38


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 119 LEGHTCEKCRELL----KPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQ 174
           L  +TCE+C + +    K   Y        + R WH+ CF C  C  +L++  +   + Q
Sbjct: 35  LFANTCEECGKPIGCDCKDLSY--------KDRHWHEACFHCSQCRNSLVDKPFAAKEDQ 86

Query: 175 LYCGRHHAELLRPRCPACDQLIF-SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGG 233
           L C   ++     +C  C + I    R  E +G  WHE  F C  C  P+G   +     
Sbjct: 87  LLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDN 146

Query: 234 SPCCPSCFENRYS 246
              C  C+E +++
Sbjct: 147 QNFCVPCYEKQHA 159



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQR--CWHQPCFACQACGQALINLIYFYHDGQLYCGRHH 181
           C++C++ + PG       R  E +   WH+ CF C  C Q +    +   D Q +C   +
Sbjct: 101 CQECKKTIMPG------TRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154

Query: 182 AELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
            +    +C  C + I +   T  E Q WH+  F C  C   L G R+        C +CF
Sbjct: 155 EKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 242 ENRYSDAGSSWAGALEG 258
            + Y+   +     + G
Sbjct: 214 CDLYAKKCAGCTNPISG 230



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%)

Query: 116 LPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQL 175
           +P  E     +C +  KP   G    R   ++ WH+ CF C AC + L    +   D   
Sbjct: 151 VPCYEKQHAMQCVQCKKPITTGGVTYR---EQPWHKECFVCTACRKQLSGQRFTARDDFA 207

Query: 176 YCGRHHAELLRPRCPACDQLIFSWRCTE---AEGQRWHENHFCCQDCAGPLGGGRYALPG 232
           YC     +L   +C  C   I     T+    E ++WH + F C+ C+  L G  +    
Sbjct: 208 YCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTER 267

Query: 233 GSPCCPSC 240
               CP C
Sbjct: 268 DDILCPDC 275



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/94 (25%), Positives = 33/94 (35%), Gaps = 1/94 (1%)

Query: 154 FACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHEN 212
           F C  C ++L    Y   +   YC      L    C  C + I    +    + + WHE 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
            F C  C   L    +A       C  C+ N YS
Sbjct: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           F C  C   L G +Y L   SP C  CFE  +++
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFAN 38


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 119 LEGHTCEKCRELL----KPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQ 174
           L  +TCE+C + +    K   Y        + R WH+ CF C  C  +L++  +   + Q
Sbjct: 35  LFANTCEECGKPIGCDCKDLSY--------KDRHWHEACFHCSQCRNSLVDKPFAAKEDQ 86

Query: 175 LYCGRHHAELLRPRCPACDQLIF-SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGG 233
           L C   ++     +C  C + I    R  E +G  WHE  F C  C  P+G   +     
Sbjct: 87  LLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDN 146

Query: 234 SPCCPSCFENRYS 246
              C  C+E +++
Sbjct: 147 QNFCVPCYEKQHA 159



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQR--CWHQPCFACQACGQALINLIYFYHDGQLYCGRHH 181
           C++C++ + PG       R  E +   WH+ CF C  C Q +    +   D Q +C   +
Sbjct: 101 CQECKKTIMPG------TRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154

Query: 182 AELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
            +    +C  C + I +   T  E Q WH+  F C  C   L G R+        C +CF
Sbjct: 155 EKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 242 ENRYSDAGSSWAGALEG 258
            + Y+   +     + G
Sbjct: 214 CDLYAKKCAGCTNPISG 230



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%)

Query: 116 LPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQL 175
           +P  E     +C +  KP   G    R   ++ WH+ CF C AC + L    +   D   
Sbjct: 151 VPCYEKQHAMQCVQCKKPITTGGVTYR---EQPWHKECFVCTACRKQLSGQRFTARDDFA 207

Query: 176 YCGRHHAELLRPRCPACDQLIFSWRCTE---AEGQRWHENHFCCQDCAGPLGGGRYALPG 232
           YC     +L   +C  C   I     T+    E ++WH + F C+ C+  L G  +    
Sbjct: 208 YCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTER 267

Query: 233 GSPCCPSC 240
               CP C
Sbjct: 268 DDILCPDC 275



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/94 (25%), Positives = 33/94 (35%), Gaps = 1/94 (1%)

Query: 154 FACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHEN 212
           F C  C ++L    Y   +   YC      L    C  C + I    +    + + WHE 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
            F C  C   L    +A       C  C+ N YS
Sbjct: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           F C  C   L G +Y L   SP C  CFE  +++
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFAN 38


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 13/133 (9%)

Query: 119 LEGHTCEKCRELL----KPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQ 174
           L  +TCE+C + +    K   Y        + R WH+ CF C  C  +L++  +   + Q
Sbjct: 35  LFANTCEECGKPIGCDCKDLSY--------KDRHWHEACFHCSQCRNSLVDKPFAAKEDQ 86

Query: 175 LYCGRHHAELLRPRCPACDQLIF-SWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGG 233
           L C   ++     +C  C + I    R  E +G  WHE  F C  C  P+G   +     
Sbjct: 87  LLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDN 146

Query: 234 SPCCPSCFENRYS 246
              C  C+E +++
Sbjct: 147 QNFCVPCYEKQHA 159



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 35/137 (25%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQR--CWHQPCFACQACGQALINLIYFYHDGQLYCGRHH 181
           C++C++ + PG       R  E +   WH+ CF C  C Q +    +   D Q +C   +
Sbjct: 101 CQECKKTIMPG------TRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154

Query: 182 AELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCF 241
            +    +C  C + I +   T  E Q WH+  F C  C   L G R+        C +CF
Sbjct: 155 EKQHAMQCVQCKKPITTGGVTYRE-QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213

Query: 242 ENRYSDAGSSWAGALEG 258
            + Y+   +     + G
Sbjct: 214 CDLYAKKCAGCTNPISG 230



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 34/128 (26%), Positives = 51/128 (39%), Gaps = 6/128 (4%)

Query: 116 LPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQL 175
           +P  E     +C +  KP   G    R   ++ WH+ CF C AC + L    +   D   
Sbjct: 151 VPCYEKQHAMQCVQCKKPITTGGVTYR---EQPWHKECFVCTACRKQLSGQRFTARDDFA 207

Query: 176 YCGRHHAELLRPRCPACDQLIFSWRCTE---AEGQRWHENHFCCQDCAGPLGGGRYALPG 232
           YC     +L   +C  C   I     T+    E ++WH + F C+ C+  L G  +    
Sbjct: 208 YCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTER 267

Query: 233 GSPCCPSC 240
               CP C
Sbjct: 268 DDILCPDC 275



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 24/94 (25%), Positives = 33/94 (35%), Gaps = 1/94 (1%)

Query: 154 FACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLI-FSWRCTEAEGQRWHEN 212
           F C  C ++L    Y   +   YC      L    C  C + I    +    + + WHE 
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64

Query: 213 HFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYS 246
            F C  C   L    +A       C  C+ N YS
Sbjct: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 214 FCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSD 247
           F C  C   L G +Y L   SP C  CFE  +++
Sbjct: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFAN 38


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 7/123 (5%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C  C  +++    G F    G  R WH   F C  C  +L ++ +      +YC R + +
Sbjct: 441 CGHCNNVIR----GPFLVAMG--RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQ 494

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
              P C  C+  I       A  Q WH   F C  C  P G   + +  G P C   + N
Sbjct: 495 FFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYIN 553

Query: 244 RYS 246
            +S
Sbjct: 554 LFS 556



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 1/93 (1%)

Query: 146 QRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSW-RCTEA 204
           ++ WH  CF C AC +   N ++   DG+ YC + +  L   +C  CD  + +  +  EA
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575

Query: 205 EGQRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
            G  WH+  F C  C   L G  +      P C
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 7/123 (5%)

Query: 124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAE 183
           C  C  +++    G F    G  R WH   F C  C  +L ++ +      +YC R + +
Sbjct: 551 CGHCNNVIR----GPFLVAMG--RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQ 604

Query: 184 LLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFEN 243
              P C  C+  I       A  Q WH   F C  C  P G   + +  G P C   + N
Sbjct: 605 FFAPLCAKCNTKIMG-EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYIN 663

Query: 244 RYS 246
            +S
Sbjct: 664 LFS 666



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 1/93 (1%)

Query: 146 QRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSW-RCTEA 204
           ++ WH  CF C AC +   N ++   DG+ YC + +  L   +C  CD  + +  +  EA
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685

Query: 205 EGQRWHENHFCCQDCAGPLGGGRYALPGGSPCC 237
            G  WH+  F C  C   L G  +      P C
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,162,915
Number of Sequences: 37866
Number of extensions: 1056848
Number of successful extensions: 4836
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 4317
Number of HSP's gapped (non-prelim): 432
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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