BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens] (348 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens] 687 0.0 gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens] 687 0.0 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 46 4e-05 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 46 6e-05 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 46 6e-05 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 46 6e-05 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 46 6e-05 gi|41322916 plectin 1 isoform 6 [Homo sapiens] 46 6e-05 gi|41322908 plectin 1 isoform 3 [Homo sapiens] 46 6e-05 gi|41322912 plectin 1 isoform 2 [Homo sapiens] 46 6e-05 gi|47607492 plectin 1 isoform 1 [Homo sapiens] 46 6e-05 gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 44 2e-04 gi|115648142 centrosomal protein 164kDa [Homo sapiens] 43 5e-04 gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 43 5e-04 gi|45439327 periplakin [Homo sapiens] 42 6e-04 gi|32698688 citron [Homo sapiens] 42 8e-04 gi|221139761 zinc finger protein 853 [Homo sapiens] 42 0.001 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 0.001 gi|148746195 trichohyalin [Homo sapiens] 42 0.001 gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 41 0.002 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.002 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 40 0.004 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.004 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 40 0.004 gi|16262452 cingulin [Homo sapiens] 40 0.004 gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 39 0.005 gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 39 0.007 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 39 0.007 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 39 0.007 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 39 0.007 >gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens] Length = 348 Score = 687 bits (1774), Expect = 0.0 Identities = 348/348 (100%), Positives = 348/348 (100%) Query: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE Sbjct: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60 Query: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD Sbjct: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120 Query: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV Sbjct: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180 Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE Sbjct: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240 Query: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ Sbjct: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300 Query: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD Sbjct: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 >gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens] Length = 348 Score = 687 bits (1774), Expect = 0.0 Identities = 348/348 (100%), Positives = 348/348 (100%) Query: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE Sbjct: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60 Query: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD Sbjct: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120 Query: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV Sbjct: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180 Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE Sbjct: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240 Query: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ Sbjct: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300 Query: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD Sbjct: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 46.2 bits (108), Expect = 4e-05 Identities = 56/179 (31%), Positives = 82/179 (45%), Gaps = 27/179 (15%) Query: 172 VRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIW 231 +R L D+ E RA L+ LR TD + A RE+ QRLR +++ Sbjct: 552 LRKQLSDSESERRALEEQLQRLR------DKTDGAMQAHEDAQREV----QRLRSANELL 601 Query: 232 IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDL 291 REK +L +VA Q EE +ER++ Q Q LR Q + L+EE+ A QD Sbjct: 602 SREK-SNLAHSLQVAQQQA------EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDG 654 Query: 292 AALYDLHVQATRAQTHHVL-PISGDGGLLAGTL---EETINLAT-QNQELQAENQQLQQ 345 A V+ ++H L + G +LA L E ++ AT Q LQAE ++ + Sbjct: 655 A-----RVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAE 708 Score = 36.2 bits (82), Expect = 0.045 Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 14/180 (7%) Query: 179 AVEEARARRAGLRPL--RLGLLEDTLTDSGLSQLGRALRELEAQ------RQRLREQHQI 230 ++ + RA A L+ +L L ++L L L R + +LE + RQR EQ Sbjct: 723 SMTKLRAEEASLQDSLSKLSALNESLAQDKLD-LNRLVAQLEEEKSALQGRQRQAEQEAT 781 Query: 231 WIREKLKHLEQ---KEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTA 287 RE+ + LE+ ++EVA ++G + E +E +Q+ LR + LQE+ Sbjct: 782 VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE--ALEQQLPTLRHERSQLQEQLAQL 839 Query: 288 EQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGA 347 + L+ QA R V + +E LA Q + E + L + A Sbjct: 840 SRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEA 899 Score = 34.7 bits (78), Expect = 0.13 Identities = 46/170 (27%), Positives = 68/170 (40%), Gaps = 17/170 (10%) Query: 180 VEEARARRAGLRPLRLGLLEDTLTDSGLSQLGR----ALRELEAQRQRLREQHQIWIREK 235 V+ R +A LR R ED L +L R A RELEA+R +L+ Q Q E Sbjct: 974 VQAEREAQASLREQRAAHEED------LQRLQREKEAAWRELEAERAQLQSQLQREQEEL 1027 Query: 236 LKHLEQKEEVADDQVKGLVAE--EEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAA 293 L LE ++E +++ L E E QQ + + AL E+ LA Sbjct: 1028 LARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAT 1087 Query: 294 L-YDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQ 342 + ++ Q AQ+ D + E +L Q +E A + Q Sbjct: 1088 ISLEMERQKRDAQSRQ----EQDRSTVNALTSELRDLRAQREEAAAAHAQ 1133 Score = 33.5 bits (75), Expect = 0.29 Identities = 39/139 (28%), Positives = 61/139 (43%), Gaps = 9/139 (6%) Query: 207 LSQLGRAL--RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQ 264 L+QL R L RE E ++ R Q Q+ E L+ +++E + GL + A E Sbjct: 836 LAQLSRQLSGREQELEQARREAQRQV---EALERAAREKEALAKEHAGLAVQLVAAEREG 892 Query: 265 RWQQEQMV-LRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTL 323 R E+ LR + EAL+ ++ LA L Q +L G LAG Sbjct: 893 RTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLR 952 Query: 324 EETI---NLATQNQELQAE 339 ++ I A+ ++EL A+ Sbjct: 953 QQIIATQEKASLDKELMAQ 971 Score = 30.0 bits (66), Expect = 3.2 Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 28/176 (15%) Query: 157 LLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216 L R++ +G+ Q+++V + A L ++ E L L L RAL + Sbjct: 1803 LQRVEAEGQLQQLREVLR------QRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQ 1856 Query: 217 LEAQRQRLR------EQHQIWIREKLKHLEQKEEVADDQVKGLVAEE------------- 257 LEA+++ + E+ ++ +R L +E+++ + + L AE+ Sbjct: 1857 LEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELE 1916 Query: 258 --EACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDL-HVQATRAQTHHVL 310 EA + Q+ + + +VL Q E + +Q L ++ +++ +AQT L Sbjct: 1917 LAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTL 1972 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1915 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1970 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1971 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2021 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2069 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2070 QQEQSVLD 2077 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1625 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1680 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1681 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1800 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1830 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1445 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1446 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAAR 1529 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1553 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1606 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1607 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1712 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1713 QELIRLRAETEQGEQ 1727 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2530 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2586 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2587 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2646 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2647 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2706 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2707 NEKLSVYAALQRQLL 2721 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQA 2127 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1924 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRI 1951 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 1976 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2088 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2089 AAEEAEEARVQAER 2102 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2211 RLKAEATEAARQRS 2224 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2254 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2308 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2309 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2368 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2369 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2422 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAE 2446 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1919 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1974 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1975 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2025 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2026 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2073 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2074 QQEQSVLD 2081 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1629 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1684 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1685 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1743 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1744 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1803 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1804 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1834 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1399 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1449 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1450 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1509 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1510 ESQRKRQAEVELASRVKAEAEAAR 1533 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1557 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1610 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1611 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1656 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1657 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1716 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1717 QELIRLRAETEQGEQ 1731 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2534 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2590 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2591 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2650 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2651 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2710 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2711 NEKLSVYAALQRQLL 2725 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 1987 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2046 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2106 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2107 EAAQSRRQVEEAERLKQSAEEQAQA 2131 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1871 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1928 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1929 EEILALKASFEKAAAGKAELELELGRI 1955 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 1980 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2036 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2037 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2092 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2093 AAEEAEEARVQAER 2106 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2095 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2155 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2214 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2215 RLKAEATEAARQRS 2228 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2258 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2312 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2313 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2372 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2373 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2426 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2427 ATQEKVTLVQTLEIQRQQSDHDAE 2450 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1915 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1970 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1971 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2021 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2069 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2070 QQEQSVLD 2077 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1625 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1680 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1681 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1800 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1830 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1445 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1446 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAAR 1529 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1553 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1606 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1607 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1712 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1713 QELIRLRAETEQGEQ 1727 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2530 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2586 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2587 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2646 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2647 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2706 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2707 NEKLSVYAALQRQLL 2721 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQA 2127 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1924 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRI 1951 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 1976 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2088 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2089 AAEEAEEARVQAER 2102 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2211 RLKAEATEAARQRS 2224 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2254 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2308 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2309 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2368 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2369 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2422 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAE 2446 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1883 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1938 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1939 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 1989 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 1990 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2037 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2038 QQEQSVLD 2045 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1593 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1648 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1649 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1707 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1708 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1767 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1768 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1798 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1363 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1413 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1414 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1473 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1474 ESQRKRQAEVELASRVKAEAEAAR 1497 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1521 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1574 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1575 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1620 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1621 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1680 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1681 QELIRLRAETEQGEQ 1695 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2498 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2554 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2555 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2614 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2615 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2674 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2675 NEKLSVYAALQRQLL 2689 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 1951 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2010 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2070 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2071 EAAQSRRQVEEAERLKQSAEEQAQA 2095 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1835 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1892 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1893 EEILALKASFEKAAAGKAELELELGRI 1919 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 1944 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2000 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2001 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2056 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2057 AAEEAEEARVQAER 2070 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2059 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2118 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2119 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2178 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2179 RLKAEATEAARQRS 2192 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2222 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2276 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2277 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2336 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2337 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2390 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2391 ATQEKVTLVQTLEIQRQQSDHDAE 2414 >gi|41322916 plectin 1 isoform 6 [Homo sapiens] Length = 4684 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 2052 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 2107 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 2108 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2158 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2159 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2206 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2207 QQEQSVLD 2214 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1762 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1817 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1818 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1876 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1877 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1936 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1937 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1967 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1532 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1582 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1583 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1642 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1643 ESQRKRQAEVELASRVKAEAEAAR 1666 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1690 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1743 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1744 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1789 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1790 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1849 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1850 QELIRLRAETEQGEQ 1864 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2667 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2723 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2724 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2783 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2784 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2843 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2844 NEKLSVYAALQRQLL 2858 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2179 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2239 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2240 EAAQSRRQVEEAERLKQSAEEQAQA 2264 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 2004 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 2061 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 2062 EEILALKASFEKAAAGKAELELELGRI 2088 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 2113 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2169 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2170 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2225 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2226 AAEEAEEARVQAER 2239 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2228 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2287 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2288 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2347 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2348 RLKAEATEAARQRS 2361 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2391 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2445 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2446 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2505 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2506 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2559 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2560 ATQEKVTLVQTLEIQRQQSDHDAE 2583 >gi|41322908 plectin 1 isoform 3 [Homo sapiens] Length = 4525 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1893 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1948 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1949 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 1999 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2000 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2047 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2048 QQEQSVLD 2055 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1603 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1658 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1659 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1717 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1718 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1777 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1778 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1808 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1373 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1423 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1424 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1483 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1484 ESQRKRQAEVELASRVKAEAEAAR 1507 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1531 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1584 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1585 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1630 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1631 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1690 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1691 QELIRLRAETEQGEQ 1705 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2508 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2564 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2565 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2624 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2625 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2684 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2685 NEKLSVYAALQRQLL 2699 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 1961 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2020 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2080 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2081 EAAQSRRQVEEAERLKQSAEEQAQA 2105 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1845 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1902 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1903 EEILALKASFEKAAAGKAELELELGRI 1929 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 1954 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2010 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2011 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2066 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2067 AAEEAEEARVQAER 2080 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2069 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2128 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2129 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2188 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2189 RLKAEATEAARQRS 2202 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2232 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2286 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2287 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2346 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2347 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2400 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2401 ATQEKVTLVQTLEIQRQQSDHDAE 2424 >gi|41322912 plectin 1 isoform 2 [Homo sapiens] Length = 4533 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1901 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1956 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1957 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2007 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2008 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2055 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2056 QQEQSVLD 2063 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1611 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1666 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1667 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1725 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1726 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1785 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1786 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1816 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1381 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1431 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1432 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1491 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1492 ESQRKRQAEVELASRVKAEAEAAR 1515 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1539 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1592 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1593 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1638 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1639 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1698 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1699 QELIRLRAETEQGEQ 1713 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2516 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2572 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2573 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2632 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2633 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2692 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2693 NEKLSVYAALQRQLL 2707 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 1969 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2028 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2088 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2089 EAAQSRRQVEEAERLKQSAEEQAQA 2113 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1853 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1910 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1911 EEILALKASFEKAAAGKAELELELGRI 1937 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 1962 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2018 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2019 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2074 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2075 AAEEAEEARVQAER 2088 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2077 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2136 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2137 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2196 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2197 RLKAEATEAARQRS 2210 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2240 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2294 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2295 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2354 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2355 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2408 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2409 ATQEKVTLVQTLEIQRQQSDHDAE 2432 >gi|47607492 plectin 1 isoform 1 [Homo sapiens] Length = 4574 Score = 45.8 bits (107), Expect = 6e-05 Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%) Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220 D +R QV++ L + E+A A +A L L LG + D+ S + ELEA Sbjct: 1942 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1997 Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E Sbjct: 1998 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2048 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340 + R AEQ+ A L +A + + L A + + QELQ Sbjct: 2049 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2096 Query: 341 QQLQQGAD 348 QQ Q D Sbjct: 2097 QQEQSVLD 2104 Score = 45.4 bits (106), Expect = 7e-05 Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%) Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193 EEAE L W L+ N L L+ + ++ + Q E ARR G + Sbjct: 1652 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1707 Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253 + + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L Sbjct: 1708 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1766 Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 E A ++RQ + E +R ++E L + AE++ + + Q A+ + Sbjct: 1767 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1826 Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + + L EE + Q AE +Q A+ Sbjct: 1827 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1857 Score = 40.0 bits (92), Expect = 0.003 Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%) Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221 +RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R Sbjct: 1422 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1472 Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279 RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++ Sbjct: 1473 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1532 Query: 280 LQEERNTAEQDLAALYDLHVQATR 303 + + AE +LA+ +A R Sbjct: 1533 ESQRKRQAEVELASRVKAEAEAAR 1556 Score = 36.6 bits (83), Expect = 0.034 Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 R+ +V++ R R+ A L+ R E T +QL R+L+E +L Sbjct: 1580 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1633 Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280 RE+ E A Q + A EEA E +RWQ E + LR Q E + Sbjct: 1634 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1679 Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 ++++ AE++ QA R + + L GT ++ + Sbjct: 1680 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1739 Query: 331 TQNQELQAENQQLQQ 345 + L+AE +Q +Q Sbjct: 1740 QELIRLRAETEQGEQ 1754 Score = 35.8 bits (81), Expect = 0.058 Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL Sbjct: 2557 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2613 Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268 A+ QRLREQ Q+ + L EEV QV + A E Sbjct: 2614 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2673 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323 + + + + LQE + ++L L H A R H L S GLL Sbjct: 2674 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2733 Query: 324 EETINL--ATQNQEL 336 E +++ A Q Q L Sbjct: 2734 NEKLSVYAALQRQLL 2748 Score = 34.3 bits (77), Expect = 0.17 Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216 RR ++V+ +L E AR R+A L + L + QL A Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2069 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268 + + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++ Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2129 Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293 E R Q+E + + +AE+ A Sbjct: 2130 EAAQSRRQVEEAERLKQSAEEQAQA 2154 Score = 33.9 bits (76), Expect = 0.22 Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ + Sbjct: 1894 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1951 Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294 +E + L+ E + E +L + Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRI 1978 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%) Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238 A EE R RR ++ L + + Q AL E+E + ++ E ++ R + + Sbjct: 2003 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2059 Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289 Q + + K L AEE+A E +Q QQEQ V L+ L+ E A + Sbjct: 2060 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2115 Query: 290 DLAALYDLHVQATR 303 + VQA R Sbjct: 2116 AAEEAEEARVQAER 2129 Score = 32.3 bits (72), Expect = 0.65 Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%) Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234 + EEAR A R + R + L S Q RA + A++ R + + R Sbjct: 2118 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2177 Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292 + + L QK+ + K E+ ++ + +QE LR QLE ++N +++L Sbjct: 2178 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2237 Query: 293 ALYDLHVQATRAQT 306 L +A R ++ Sbjct: 2238 RLKAEATEAARQRS 2251 Score = 30.0 bits (66), Expect = 3.2 Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215 L+LR +R ++ A E AR A RL L + L+Q RAL Sbjct: 2281 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2335 Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267 E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q Sbjct: 2336 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2395 Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324 + Q L EA + + AE A A + Q R Q + G L T Sbjct: 2396 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2449 Query: 325 ETINLATQNQELQAENQQLQQGAD 348 T T Q L+ + QQ A+ Sbjct: 2450 ATQEKVTLVQTLEIQRQQSDHDAE 2473 >gi|145312241 differentially expressed in FDCP 6 homolog [Homo sapiens] Length = 631 Score = 44.3 bits (103), Expect = 2e-04 Identities = 39/168 (23%), Positives = 76/168 (45%), Gaps = 27/168 (16%) Query: 147 LLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSG 206 L E + LL+ + + RR Q ++++ L + EA RA ++ E L + Sbjct: 367 LQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQA------EMELKEEE 420 Query: 207 LSQLGRALRELEAQRQRLREQHQIWIR--------------------EKLKHLEQKEEVA 246 ++ + ++ELE +QRL+E Q+ ++ EKLK L Q +E Sbjct: 421 AARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQ 480 Query: 247 DDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEALQEERNTAEQDLAA 293 + ++ E+E ++ Q + + QLE +++ R A++D+ A Sbjct: 481 ERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEA 528 Score = 34.7 bits (78), Expect = 0.13 Identities = 43/204 (21%), Positives = 85/204 (41%), Gaps = 23/204 (11%) Query: 161 DPQGRRMQ--VKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELE 218 D G+R VK T + + R R+ +++ + L G + L + L++ Sbjct: 273 DRDGKRCMFCVKTANRTYEMSASDTRQRQEWTAAIQMAI---RLQAEGKTSLHKDLKQKR 329 Query: 219 AQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA--------CEERQRWQQEQ 270 +++ RE+ + E+L L+Q +E + +++ L +EA EE +R + + Sbjct: 330 REQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQH 389 Query: 271 MVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTL------- 323 L+ LE E A + A +L + Q + + L L Sbjct: 390 RELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKAR 449 Query: 324 --EETINLATQNQELQAENQQLQQ 345 EE++ +A Q + L+ E ++L+Q Sbjct: 450 RDEESVRIA-QTRLLEEEEEKLKQ 472 >gi|115648142 centrosomal protein 164kDa [Homo sapiens] Length = 1460 Score = 42.7 bits (99), Expect = 5e-04 Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 15/187 (8%) Query: 157 LLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216 +LRL Q + + +R L A+EE AR RL L + S + + E Sbjct: 633 ILRLHQQ-KEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAE 691 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276 EA Q+LRE+ + + + LEQK +Q+K + E E+ ++ L+ Sbjct: 692 QEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQL 751 Query: 277 LEALQEERN----TAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQ 332 E L+ ER T E++ +A + + A+ V+ +L++ I A Q Sbjct: 752 REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVV----------SSLQKKIQEAQQ 801 Query: 333 NQELQAE 339 +E Q + Sbjct: 802 KEEAQLQ 808 >gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] Length = 2115 Score = 42.7 bits (99), Expect = 5e-04 Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 16/154 (10%) Query: 208 SQLGRALRELEAQRQRLREQHQIWI-----REKLKHLEQKEEVADDQVKGLVAEEEAC-- 260 + LGR E+E + R + ++ +L ++++ + +++ + A+ E Sbjct: 1458 ANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 1517 Query: 261 ---EERQRWQQEQMVLRF---QLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISG 314 EERQR+Q+E+ L QLE Q E+ ++L+ QA++ Q + + Sbjct: 1518 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQA 1577 Query: 315 DGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 GG + +E L Q ELQA+ Q +Q A+ Sbjct: 1578 QGG---ESQQEAQRLQAQLNELQAQLSQKEQAAE 1608 Score = 33.5 bits (75), Expect = 0.29 Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 17/144 (11%) Query: 208 SQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267 SQ+ R + +L + L + +RE HL+Q ++ ++ EE + Q W Sbjct: 307 SQMDRKINQLSEENGDLSFK----LREFASHLQQLQDALNE------LTEEHSKATQEWL 356 Query: 268 QEQMVLRFQLEA-------LQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLA 320 ++Q L +L A L+E+ + L+ L + Q + GD L Sbjct: 357 EKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLE 416 Query: 321 GTLEETINLATQNQELQAENQQLQ 344 +E LA N +LQA + L+ Sbjct: 417 TLKQEAATLAANNTQLQARVEMLE 440 Score = 32.0 bits (71), Expect = 0.84 Identities = 26/114 (22%), Positives = 59/114 (51%), Gaps = 2/114 (1%) Query: 178 DAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLK 237 +A+E+ +A + + +L + + DS + + +A RE +++ E + + Sbjct: 607 EALEKEKAAKLEILQQQLQVANEA-RDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665 Query: 238 HLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDL 291 E + +VA+ +++ L +E++ E++R QE+ L+ QL+AL+E + L Sbjct: 666 QHEAQAQVAELELQ-LRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSL 718 Score = 31.6 bits (70), Expect = 1.1 Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 16/156 (10%) Query: 205 SGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE------ 258 +GL Q + + AQ + +EQ +R +++ L + + Q+K + ++E Sbjct: 522 AGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDH 581 Query: 259 ------ACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312 A EER+ +E+ QLEAL++E+ + L + +A + V Sbjct: 582 AQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQA 641 Query: 313 SGDGGLLAGTLEE---TINLATQNQ-ELQAENQQLQ 344 + L+ +EE + A Q Q E QA+ +L+ Sbjct: 642 QREKAELSRKVEELQACVETARQEQHEAQAQVAELE 677 Score = 30.8 bits (68), Expect = 1.9 Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 17/169 (10%) Query: 181 EEARARRAGLRPLRLGLLEDTLTDS-GLSQLGRALRELEAQRQRLREQHQIWIREKLKHL 239 E+ +A + L+ + L E+ + L + R + EL+A+ + L EQH+ RE+ K L Sbjct: 702 EQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK---RER-KEL 757 Query: 240 EQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHV 299 E++ KGL A + E Q E VLR +L ++TAE + L V Sbjct: 758 EEERAGR----KGLEARLQQLGEAH--QAETEVLRRELAEAMAAQHTAESECEQL----V 807 Query: 300 QATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348 + A + +E L T +E + Q+LQ+ + Sbjct: 808 KEVAAWRERYEDSQQEEAQYGAMFQE--QLMTLKEECEKARQELQEAKE 854 >gi|45439327 periplakin [Homo sapiens] Length = 1756 Score = 42.4 bits (98), Expect = 6e-04 Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 33/169 (19%) Query: 198 LEDTLTDSGLSQLGRALRELEAQRQRLRE--------QHQIWI------REKLKHLEQKE 243 L+ DSG+ + + +EL+ + +R R+ Q +IW +E + E + Sbjct: 880 LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLK 939 Query: 244 EVAD-------DQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYD 296 +V D Q++ +AEE+ + Q Q+E L+ QL AL++E Q+ Sbjct: 940 KVPDPVLEESFQQLQRTLAEEQ--HKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEV 997 Query: 297 LHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQ 345 L ++ RAQ VL + EE L Q +AE LQQ Sbjct: 998 LRIEPDRAQADEVLQLR----------EELEALRRQKGAREAEVLLLQQ 1036 Score = 40.4 bits (93), Expect = 0.002 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 4/137 (2%) Query: 208 SQLGRALRELEAQRQRLREQHQ--IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR 265 ++L R L ELE +RQ RE + ++++L LEQ+E A ++V ++ ++ + Sbjct: 1397 TELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTH--TQKVVLQQDPQ 1454 Query: 266 WQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEE 325 +E +LR QLE Q R E +L L +A+ + +S + G E+ Sbjct: 1455 QAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQ 1514 Query: 326 TINLATQNQELQAENQQ 342 I + E ++ +++ Sbjct: 1515 EIQRLKSSLEEESRSKR 1531 Score = 31.2 bits (69), Expect = 1.4 Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 37/139 (26%) Query: 157 LLRLDP-QGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLE--------------DT 201 +LR++P + + +V Q+R L EA R+ G R + LL+ + Sbjct: 997 VLRIEPDRAQADEVLQLREEL-----EALRRQKGAREAEVLLLQQRVAALAEEKSRAQEK 1051 Query: 202 LTDSGLSQLGRALRELEAQRQRLREQHQ-------------IWIREKLKHLEQKEEVADD 248 +T+ + +L +LEA+ Q+L+E HQ ++++KLK LE++ +A+ Sbjct: 1052 VTEKEVVKLQND-PQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEG 1110 Query: 249 QV---KGLVAEEEACEERQ 264 ++ + L E++A ER+ Sbjct: 1111 KITVKEVLKVEKDAATERE 1129 Score = 29.6 bits (65), Expect = 4.2 Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 23/142 (16%) Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227 +VK + +W + + + +R L + D + + QL R L E + + Q L+E+ Sbjct: 912 EVKSTQEEIW-TLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQLLQEE 970 Query: 228 HQIWIREKLKHLEQK------------------EEVADDQVKGLVAEEEACEERQRWQQE 269 + ++ +L+ LEQ+ + D+V L E EA RQ+ +E Sbjct: 971 LEA-LQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALR-RQKGARE 1028 Query: 270 QMVLRFQ--LEALQEERNTAEQ 289 VL Q + AL EE++ A++ Sbjct: 1029 AEVLLLQQRVAALAEEKSRAQE 1050 Score = 28.5 bits (62), Expect = 9.3 Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 18/120 (15%) Query: 180 VEEARARRAGLRPLR--LGLLEDTLTDSGLSQLGR-----ALRELEAQRQRLREQHQIW- 231 +E+ RA G ++ L + +D T+ +S L R A + +QR++ +IW Sbjct: 1101 LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160 Query: 232 ---------IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQM-VLRFQLEALQ 281 ++EK++ + + + A+ +V L E E + R +EQ+ + +LEAL+ Sbjct: 1161 LEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALR 1220 >gi|32698688 citron [Homo sapiens] Length = 2027 Score = 42.0 bits (97), Expect = 8e-04 Identities = 29/140 (20%), Positives = 69/140 (49%), Gaps = 8/140 (5%) Query: 214 LRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQ--- 270 L E + Q + ++ +++K +H E+K +V D+Q+K +A++E E + +E+ Sbjct: 696 LEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHE 755 Query: 271 --MVLRFQ---LEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEE 325 +L Q + A+ + + EQ + L + + A + + +++ ++ Sbjct: 756 KGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQ 815 Query: 326 TINLATQNQELQAENQQLQQ 345 L TQ +L+A+N++L++ Sbjct: 816 KFYLETQAGKLEAQNRKLEE 835 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 41.6 bits (96), Expect = 0.001 Identities = 33/137 (24%), Positives = 67/137 (48%), Gaps = 10/137 (7%) Query: 215 RELEAQRQRLREQHQIW---IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ--- 268 +EL+ + Q + +Q Q+ ++E+ + +Q+E++ Q + E++ +++++ QQ Sbjct: 144 QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ----EQQVLQQQEQLQQQVQ 199 Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETIN 328 EQ +L+ Q E LQ+++ +Q+ Q + Q L + G L L + Sbjct: 200 EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQ 259 Query: 329 LATQNQELQAENQQLQQ 345 Q Q L+ + QLQQ Sbjct: 260 AQLQQQLLEQQQAQLQQ 276 Score = 35.0 bits (79), Expect = 0.100 Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 10/125 (8%) Query: 160 LDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRAL-RELE 218 L Q ++Q +Q++P + EE L P+ LG ++ L Q + L R+ E Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEEEEEVELE-LMPVDLG------SEQELEQQRQELERQQE 347 Query: 219 AQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLE 278 +RQ+ + Q Q+ ++E+L+ LEQ+ E Q++ + E QQ+++ L +L Sbjct: 348 LERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL--ELT 405 Query: 279 ALQEE 283 +Q E Sbjct: 406 PVQPE 410 Score = 34.7 bits (78), Expect = 0.13 Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 5/135 (3%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVA----DDQVKGLVAEEEACEERQRWQQEQ 270 ++ + Q Q+++EQ ++ +++ +Q +E +Q++ V E++ +++Q Q+Q Sbjct: 155 QQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ 214 Query: 271 MVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330 +L+ Q + Q++ ++ L L + + Q L + L L E Sbjct: 215 QLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL-LQQQQAQLQQQLLEQQQAQ 273 Query: 331 TQNQELQAENQQLQQ 345 Q Q L + +QLQQ Sbjct: 274 LQQQLLLQQQEQLQQ 288 Score = 30.8 bits (68), Expect = 1.9 Identities = 41/191 (21%), Positives = 82/191 (42%), Gaps = 35/191 (18%) Query: 163 QGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQ 222 Q + QV Q + L V+E + L ++ L L Q L++ + Q+Q Sbjct: 181 QAQEQQVLQQQEQLQQQVQEQQL---------LQQQQEQLQQQQLLQQQEQLQQQQFQQQ 231 Query: 223 R--LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280 + L++Q Q+ + ++ L+Q+ L+ +++A ++Q +Q+Q L+ QL L Sbjct: 232 QEQLQQQQQLLLLQQQGQLQQQ----------LLQQQQAQLQQQLLEQQQAQLQQQL-LL 280 Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLAT------QNQ 334 Q++ +Q L + + Q P+ + EE + L Q Sbjct: 281 QQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEE-------EEEVELELMPVDLGSEQ 333 Query: 335 ELQAENQQLQQ 345 EL+ + Q+L++ Sbjct: 334 ELEQQRQELER 344 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 41.6 bits (96), Expect = 0.001 Identities = 25/89 (28%), Positives = 53/89 (59%), Gaps = 4/89 (4%) Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 ++ Q++++REQ + IW +E+ K EQ+E + + + K EE+ CE+ ++ Q+++ +R Sbjct: 579 KIREQKEKIREQEEKIWEQEE-KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637 Query: 275 FQLEAL--QEERNTAEQDLAALYDLHVQA 301 Q E + QE R +++ + H++A Sbjct: 638 RQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666 Score = 38.5 bits (88), Expect = 0.009 Identities = 17/77 (22%), Positives = 48/77 (62%), Gaps = 1/77 (1%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++REQ + IRE+ + + ++EE+ +Q + + +EE +E+++ ++++ +R Q E Sbjct: 521 QEEKIREQEEK-IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579 Query: 280 LQEERNTAEQDLAALYD 296 ++E++ + +++ Sbjct: 580 IREQKEKIREQEEKIWE 596 Score = 37.4 bits (85), Expect = 0.020 Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 6/81 (7%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQK----EEVADDQVKGLVAEEEACEERQR--WQQE 269 E+ Q +++REQ +IW +++ H ++K EE Q + + +EE E++ W+QE Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522 Query: 270 QMVLRFQLEALQEERNTAEQD 290 + + + + ++E EQ+ Sbjct: 523 EKIREQEEKIREQEEKIREQE 543 Score = 36.6 bits (83), Expect = 0.034 Identities = 19/83 (22%), Positives = 48/83 (57%), Gaps = 2/83 (2%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 ++ R ++ Q + +++ ++W +E+ H +Q+E++ + + K EE+ E+ ++ ++ Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMH-DQEEKIREQEEKMWRQEEKIREQEEKIRE 534 Query: 269 EQMVLRFQLEALQE-ERNTAEQD 290 ++ +R Q E +QE E EQ+ Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQE 557 Score = 36.2 bits (82), Expect = 0.045 Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 6/78 (7%) Query: 212 RALRELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQR 265 R ++ Q +++REQ + +W IRE+ + + ++EE +Q + + +EE E++ Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558 Query: 266 WQQEQMVLRFQLEALQEE 283 QEQ +R Q E ++E+ Sbjct: 559 KMQEQEKMRRQEEKIREQ 576 Score = 35.4 bits (80), Expect = 0.076 Identities = 21/87 (24%), Positives = 49/87 (56%), Gaps = 4/87 (4%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVL 273 ++ Q +++REQ + IRE+ + + ++EE +Q + + +EE +E++ W+QE+ + Sbjct: 565 KMRRQEEKIREQEE-KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623 Query: 274 RFQLEALQEERNTAEQDLAALYDLHVQ 300 Q E +QE+ + +++ V+ Sbjct: 624 E-QEEKMQEQEEKMRRQEEKMWEQEVR 649 Score = 33.9 bits (76), Expect = 0.22 Identities = 30/131 (22%), Positives = 67/131 (51%), Gaps = 12/131 (9%) Query: 168 QVKQVRPTLWDAVEEARARRAGL--RPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLR 225 ++++ +W+ E+ R + + + ++ LE+ + + + R L E +++++R Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK--EEKIRELEEKMHEQEKIR 393 Query: 226 EQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACE-ERQRWQQEQMVLRFQLEA 279 EQ + IRE+ K EQ+ ++ + K EE+ E E++ W+QE+ + + E Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI--HEQEK 451 Query: 280 LQEERNTAEQD 290 ++EE EQ+ Sbjct: 452 IREEEKRQEQE 462 Score = 33.1 bits (74), Expect = 0.38 Identities = 22/113 (19%), Positives = 55/113 (48%), Gaps = 4/113 (3%) Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIR----EKLKHLEQKEEVADDQVKG 252 LL + LG+ L+ + A+ Q E++++W R ++ K Q+E++ + + K Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316 Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQ 305 EE+ E+ ++ ++++ +R Q E + E+ + +++ + R + Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369 Score = 32.7 bits (73), Expect = 0.49 Identities = 20/81 (24%), Positives = 45/81 (55%), Gaps = 4/81 (4%) Query: 208 SQLGRALRELEAQRQRLREQHQ-IWIREKLKHLEQK---EEVADDQVKGLVAEEEACEER 263 +++ R ++ Q +++REQ + +W +E+ H ++K EE +Q + EE+ E+ Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475 Query: 264 QRWQQEQMVLRFQLEALQEER 284 + W+Q++ + + QEE+ Sbjct: 476 EIWRQKEKMHEQEKIRKQEEK 496 Score = 31.2 bits (69), Expect = 1.4 Identities = 27/131 (20%), Positives = 60/131 (45%), Gaps = 7/131 (5%) Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLR 225 ++Q + LW+ + + + + + ++ E+ + + ++ ++ Q +++R Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-EKIREQEEKIREQEEKMR 338 Query: 226 EQHQI-WIRE-KLKHLEQ----KEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q ++ W +E K++ E+ KEE + + +EE E + EQ +R Q E Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398 Query: 280 LQEERNTAEQD 290 QEE EQ+ Sbjct: 399 RQEEEKIREQE 409 Score = 30.0 bits (66), Expect = 3.2 Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 14/87 (16%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVK------------GLVAEEEACEER 263 ++ Q +R ++ ++W R++ K EQ+E++ + + K + EE+ E+ Sbjct: 404 KIREQEKRQEQEAKMW-RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462 Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290 + W+QE+ + R Q E +++ EQ+ Sbjct: 463 EMWRQEEKI-REQEEIWRQKEKMHEQE 488 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 41.6 bits (96), Expect = 0.001 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 3/121 (2%) Query: 173 RPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWI 232 R T+ EE R L E+ L +L R +E E Q+QRLR + Q+ Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308 Query: 233 REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ---EQMVLRFQLEALQEERNTAEQ 289 +++ + EQ+EE + Q + EE ++ +R Q+ EQ + R Q E +E++ EQ Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368 Query: 290 D 290 + Sbjct: 369 E 369 Score = 41.2 bits (95), Expect = 0.001 Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 9/150 (6%) Query: 147 LLEGNNYSGLLLRLDPQGRRMQVKQV--RPTLWDAVEEARARRAGLRPLRLGLLED---- 200 L EG S RL+ + R+ + +++ + W EE RA L+ + E+ Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207 Query: 201 -TLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA 259 L L +L R RE E Q+QR Q +++ E+ K ++E V + + L EEE Sbjct: 208 EQLRRRELLELRRKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL-QEEEP 265 Query: 260 CEERQRWQQEQMVLRFQLEALQEERNTAEQ 289 +R+ ++E+ + + + + L+ ER EQ Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQ 295 Score = 38.5 bits (88), Expect = 0.009 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 5/86 (5%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 Q R RE E + Q L E+ Q+ RE+ + L+++E+ + + ++E+ +++ RWQ Sbjct: 819 QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL 878 Query: 269 EQMVLR-----FQLEALQEERNTAEQ 289 E+ R + ALQE+ +Q Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQ 904 Score = 34.3 bits (77), Expect = 0.17 Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 23/143 (16%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 L+L+ + RR Q ++ L EE R +R L+ + L Q R+ ++L Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQR----------LKRQEEEERLQQRLRSEQQL 538 Query: 218 EAQRQRLREQHQIWIREKLKHLEQ-------KEEVADDQVKGLVAEEEACEERQRWQQ-- 268 +++ REQ + RE+ K LEQ K E + + + L EEE ++R + +Q Sbjct: 539 RREQEERREQ--LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596 Query: 269 --EQMVLRFQLEALQEERNTAEQ 289 EQ + R ++E L++E ++ Sbjct: 597 RLEQRLKREEVERLEQEERREQR 619 Score = 33.1 bits (74), Expect = 0.38 Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 11/131 (8%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 R+L A+ ++ REQ + E+ + ++ + +++ + EEE + R+R QQ Q Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ-FLEEEEQLQRRERAQQLQEE-E 853 Query: 275 FQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQ 334 L+ QE R + EQ + ++ R + H L L+E L + Q Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL-------YAKPALQE--QLRKEQQ 904 Query: 335 ELQAENQQLQQ 345 LQ E ++LQ+ Sbjct: 905 LLQEEEEELQR 915 Score = 32.7 bits (73), Expect = 0.49 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 12/131 (9%) Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217 LR + Q RR Q ++ R L EE R + R RL ++ D L RE Sbjct: 532 LRSEQQLRREQEER-REQLLKREEEKRLEQER-REQRLKREQEERRDQLLK------REE 583 Query: 218 EAQRQRLREQHQIWIREKLKHLE----QKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273 E ++QRL+ + + + ++LK E ++EE + ++K EEE ++ + ++++ Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643 Query: 274 RFQLEALQEER 284 + QL Q+ER Sbjct: 644 QQQLRREQQER 654 Score = 32.0 bits (71), Expect = 0.84 Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 7/85 (8%) Query: 212 RALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC-------EERQ 264 R RE + R + R+ W E+L+ EQ++ + ++ + AEE+ EE++ Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863 Query: 265 RWQQEQMVLRFQLEALQEERNTAEQ 289 WQ+E+ R + E E + Q Sbjct: 1864 LWQEEEQKRRQERERKLREEHIRRQ 1888 Score = 31.6 bits (70), Expect = 1.1 Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275 +LE Q QRLR++ R + + Q++ ++Q E++ +ER+R +E+ + R Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888 Query: 276 QLEALQEERNTAE 288 Q E Q R E Sbjct: 1889 QKEE-QRHRQVGE 1900 Score = 30.8 bits (68), Expect = 1.9 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 15/110 (13%) Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240 EE RAR G + LL+D + + R+LE + + R Q K E Sbjct: 97 EEKRARCDG----KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ---------KRQE 143 Query: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290 Q+ E+A+ + + ++E E+R R ++++ + R + E + E AE++ Sbjct: 144 QERELAEGEEQS--EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEE 191 Score = 30.8 bits (68), Expect = 1.9 Identities = 17/75 (22%), Positives = 43/75 (57%), Gaps = 2/75 (2%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 R+ + +R + E+ + W++ + + +++E + Q++ +EE E+R + Q+E+ L+ Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR--EQEERREQRLKRQEEEERLQ 529 Query: 275 FQLEALQEERNTAEQ 289 +L + Q+ R E+ Sbjct: 530 QRLRSEQQLRREQEE 544 Score = 30.4 bits (67), Expect = 2.5 Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 9/77 (11%) Query: 216 ELEAQRQRL-REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 E E + QRL REQ + R+ LK E+ E ++ K + ++ E R+RW L+ Sbjct: 439 EQERREQRLKREQEER--RDWLKREEETERHEQERRKQQLKRDQEEERRERW------LK 490 Query: 275 FQLEALQEERNTAEQDL 291 + E +E++ EQ L Sbjct: 491 LEEEERREQQERREQQL 507 Score = 30.4 bits (67), Expect = 2.5 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 8/90 (8%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVAD-DQVKGLVAEEEACEERQRW- 266 Q G+ R+ + +++R RE W E+ H +Q+EE D AEE++ RQR Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785 Query: 267 ------QQEQMVLRFQLEALQEERNTAEQD 290 +Q + LR + +E+R E++ Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEE 815 Score = 30.4 bits (67), Expect = 2.5 Identities = 19/82 (23%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query: 218 EAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQ----RWQQEQMVL 273 + + Q LRE+ + R++L+ ++EE + + L+ EE RQ ++++E+ + Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177 Query: 274 RFQLEALQEERNTAEQDLAALY 295 + + + L+EE+ Q+ Y Sbjct: 1178 QEEEQLLREEQEKRRQERERQY 1199 Score = 29.6 bits (65), Expect = 4.2 Identities = 23/72 (31%), Positives = 41/72 (56%), Gaps = 8/72 (11%) Query: 214 LRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQMV 272 LRE +R+R + Q K K L+QKEE Q+ G E+ +ER+ ++++E+ + Sbjct: 944 LREEREKRRRQERERQY---RKDKKLQQKEE----QLLGEEPEKRRRQEREKKYREEEEL 996 Query: 273 LRFQLEALQEER 284 + + + L+EER Sbjct: 997 QQEEEQLLREER 1008 Score = 29.3 bits (64), Expect = 5.5 Identities = 26/125 (20%), Positives = 59/125 (47%), Gaps = 5/125 (4%) Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224 RR + K+++ + + R R L+ GL ED Q + + +R Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883 Query: 225 REQHQIWIREKL-KHLEQKEEVADDQVKGLVAEEEACEERQ----RWQQEQMVLRFQLEA 279 R +H ++ + L + L +++++ ++ + L EE RQ ++++E+ + + + + Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943 Query: 280 LQEER 284 L+EER Sbjct: 944 LREER 948 Score = 29.3 bits (64), Expect = 5.5 Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 11/130 (8%) Query: 161 DPQGRRMQVKQVRPTLWD-AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA 219 + Q RR +Q R W +EE R RR + L E + L Q E Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ--------EE 909 Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 + + RE+ + R++ + ++EE + + L+ EE E+R+R ++E+ + + Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER--EKRRRQERERQYRKDKKLQ 967 Query: 280 LQEERNTAEQ 289 +EE+ E+ Sbjct: 968 QKEEQLLGEE 977 Score = 28.9 bits (63), Expect = 7.1 Identities = 22/86 (25%), Positives = 46/86 (53%), Gaps = 8/86 (9%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKE--------EVADDQVKGLVAEEEAC 260 QL ++ + E ++Q+LR + Q ++LK E++E E +++ + +AEEE Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691 Query: 261 EERQRWQQEQMVLRFQLEALQEERNT 286 + R+R + ++QLE+ + R + Sbjct: 692 QARERIKSRIPKWQWQLESEADARQS 717 Score = 28.9 bits (63), Expect = 7.1 Identities = 38/160 (23%), Positives = 60/160 (37%), Gaps = 17/160 (10%) Query: 197 LLEDTLTDSGLSQLGRALRELEA----QRQRLREQHQIWIREKLKHLEQKEEVADDQVKG 252 LL + L + R RE E + Q L E+ + R++L+ +KEE + + Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092 Query: 253 LVAEE----------EACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQAT 302 L+ EE C E + QQE+ L L +E+R E + + VQ Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQL---LREEREKRRRQELERQYREEEEVQQE 1149 Query: 303 RAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQ 342 Q P L E L + ++L E Q+ Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189 Score = 28.5 bits (62), Expect = 9.3 Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 16/143 (11%) Query: 159 RLDPQGRRMQVKQVRPTLWDAV--EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216 RL+ + R ++K+ + D + E R+ L+ + LE L + +L + Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL----EQ 612 Query: 217 LEAQRQRL-REQHQIWIREKLKHLEQKEEVADDQVKG---------LVAEEEACEERQRW 266 E + QRL RE+ + R++L E++EE Q++ L EEE QR Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672 Query: 267 QQEQMVLRFQLEALQEERNTAEQ 289 ++E R + E +EE+ A + Sbjct: 673 KREHEEERREQELAEEEQEQARE 695 >gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] Length = 248 Score = 40.8 bits (94), Expect = 0.002 Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 12/183 (6%) Query: 169 VKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSG-LSQLGRALRELEAQRQRLREQ 227 VK+ L +EA R GL+ G E G ++ L R ++ +E + R +E+ Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69 Query: 228 HQIWIREKLKHLEQKEEVADDQVKGL-VAEEEACEERQRWQQEQMVLRFQLEALQEERNT 286 + L+ LE+ E+ AD+ +G+ V E A ++ ++ + ++M L+ +E Sbjct: 70 ----LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125 Query: 287 AEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQN-QELQAENQQLQQ 345 E+ L L + RA+ + L G LEE + T N + L+A +++ + Sbjct: 126 YEEVARKLVILEGELERAEERAEV-----SELKCGDLEEELKNVTNNLKSLEAASEKYSE 180 Query: 346 GAD 348 D Sbjct: 181 KED 183 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 40.4 bits (93), Expect = 0.002 Identities = 31/138 (22%), Positives = 66/138 (47%), Gaps = 8/138 (5%) Query: 159 RLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELE 218 RL Q +M+ ++ + +W + R + LR L E Q+ ++ Sbjct: 301 RLREQEGKMREQEEK--MWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358 Query: 219 AQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV 272 Q +++REQ + +W + E+ K + ++E+ DQ + + ++E E++ +EQ Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418 Query: 273 LRFQLEALQEERNTAEQD 290 + Q+E ++EE+ EQ+ Sbjct: 419 MWEQVEKMREEKKMQEQE 436 Score = 38.5 bits (88), Expect = 0.009 Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQV 250 LL T++ ++ R EL Q +++R+Q + +W +RE+ + ++EE Q Sbjct: 261 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE 320 Query: 251 KGLVAEEEACEERQRWQQEQMVLRFQLEALQEE 283 K L +E+ E+++ +EQ LR Q E +QE+ Sbjct: 321 KRLREQEKELREQEKELREQKELREQEEQMQEQ 353 Score = 37.7 bits (86), Expect = 0.015 Identities = 21/83 (25%), Positives = 50/83 (60%), Gaps = 4/83 (4%) Query: 216 ELEAQRQRLREQHQIWIREKL-KHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQMVL 273 +++ Q + ++ +IW +EK+ K +++E+ DQ K + EEE+ ER+ + ++E+ ++ Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK--MREEESMREREKKMREEEEMM 729 Query: 274 RFQLEALQEERNTAEQDLAALYD 296 R Q E +QE+ ++ +++ Sbjct: 730 REQEEKMQEQEEKMQEQEEEMWE 752 Score = 36.6 bits (83), Expect = 0.034 Identities = 30/130 (23%), Positives = 64/130 (49%), Gaps = 9/130 (6%) Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA----QR 221 ++Q ++ +W EE R + +R + + L + +RE E Q Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ---EERLREQEGKMREQEEKMWRQE 320 Query: 222 QRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRW-QQEQMVLRFQLEAL 280 +RLREQ + +RE+ K L +++E+ + + + EE+ E+ ++ +QE+ + R + Sbjct: 321 KRLREQEKE-LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379 Query: 281 QEERNTAEQD 290 ++E+ EQ+ Sbjct: 380 EQEKQMREQE 389 Score = 36.6 bits (83), Expect = 0.034 Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%) Query: 214 LRELEAQRQR---LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQ 270 +RE E+ R+R +RE+ ++ +RE+ + ++++EE +Q + + +EE E++ EQ Sbjct: 709 MREEESMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767 Query: 271 MVLRFQLEALQEERNTAEQD 290 L Q E L E EQ+ Sbjct: 768 QRLPEQKEKLWEHEKMQEQE 787 Score = 35.8 bits (81), Expect = 0.058 Identities = 23/81 (28%), Positives = 49/81 (60%), Gaps = 7/81 (8%) Query: 214 LRELEAQRQR---LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQ 268 +RE E R+R +RE+ ++ +RE+ + ++++EE +Q + + +EE +E++ W+Q Sbjct: 585 MREEERMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643 Query: 269 EQMVLRFQLEALQEERNTAEQ 289 E+ + Q E + E++ EQ Sbjct: 644 EEKMWE-QEEKMWEQQRLPEQ 663 Score = 35.4 bits (80), Expect = 0.076 Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 5/84 (5%) Query: 212 RALRELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRW 266 R ++++ Q ++ R+Q + IRE+ K + ++EE +Q + + +EE E++ Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486 Query: 267 QQEQMVLRFQLEALQEERNTAEQD 290 + +Q L Q E L E+ EQ+ Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQE 510 Score = 34.7 bits (78), Expect = 0.13 Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 17/90 (18%) Query: 217 LEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQ------- 264 L + +R+REQ ++W +RE+ K EQ+++ D + K + EEE ER+ Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK--MQEEERIREREKKMREEE 463 Query: 265 ---RWQQEQMVLRFQLEALQEERNTAEQDL 291 R Q+E+M + + QEE+ +Q L Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRL 493 Score = 33.9 bits (76), Expect = 0.22 Identities = 19/71 (26%), Positives = 43/71 (60%), Gaps = 5/71 (7%) Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVLRFQLE 278 ++++RE+ + RE+ K + ++EE+ +Q + + +EE +E++ W+QE+ + Q E Sbjct: 706 QEKMREEESM--REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE-QEE 762 Query: 279 ALQEERNTAEQ 289 + E++ EQ Sbjct: 763 KMWEQQRLPEQ 773 Score = 33.5 bits (75), Expect = 0.29 Identities = 22/82 (26%), Positives = 48/82 (58%), Gaps = 7/82 (8%) Query: 220 QRQRLREQHQ-IWIREKL---KHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQMVLR 274 Q +++R+Q Q +W +E+ K EQ+++ D + K + EEE ER+ + ++E+ ++R Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK--MREEERMREREKKMREEEEMMR 606 Query: 275 FQLEALQEERNTAEQDLAALYD 296 Q E +QE+ ++ +++ Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWE 628 Score = 33.1 bits (74), Expect = 0.38 Identities = 22/76 (28%), Positives = 44/76 (57%), Gaps = 10/76 (13%) Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 E E Q+QRL EQ + +W +EK++ EQ+E++ + EE+ ++ + W QE+ + R Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQ--EQEEKIWEQ-------EEKIRDQEEMWGQEKKMWR 535 Query: 275 FQLEALQEERNTAEQD 290 + QE++ +++ Sbjct: 536 QEKMREQEDQMWEQEE 551 Score = 32.7 bits (73), Expect = 0.49 Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 3/75 (4%) Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQEQMVLRF 275 + Q ++++EQ + ++ K EQ+E++ + + K EE+ E+ ++ W+Q++ L Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR--LPE 662 Query: 276 QLEALQEERNTAEQD 290 Q E L E EQ+ Sbjct: 663 QKEKLWEHEKMQEQE 677 Score = 32.3 bits (72), Expect = 0.65 Identities = 17/75 (22%), Positives = 45/75 (60%), Gaps = 2/75 (2%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275 +++ Q ++++EQ + ++ K EQ+E++ + + K EE+ E+++ +Q++ + + Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL--W 668 Query: 276 QLEALQEERNTAEQD 290 + E +QE+ EQ+ Sbjct: 669 EHEKMQEQEKMQEQE 683 Score = 32.3 bits (72), Expect = 0.65 Identities = 18/76 (23%), Positives = 44/76 (57%), Gaps = 2/76 (2%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 +++ + + +REQ + ++ K EQ+EE+ + + K EE+ E+++ +Q++ + Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL-- 777 Query: 275 FQLEALQEERNTAEQD 290 ++ E +QE+ EQ+ Sbjct: 778 WEHEKMQEQEKIWEQE 793 Score = 32.0 bits (71), Expect = 0.84 Identities = 24/78 (30%), Positives = 44/78 (56%), Gaps = 7/78 (8%) Query: 220 QRQRLREQHQ-IWIREKLKHLE---QKEEVADDQVKGLVAEEEAC---EERQRWQQEQMV 272 ++QRL EQ + +W EK++ E ++EE DQ + + +EE EE+ R Q+E+M Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMW 825 Query: 273 LRFQLEALQEERNTAEQD 290 + + QEE+ +++ Sbjct: 826 GQEEKMWGQEEKMWGQEE 843 Score = 30.8 bits (68), Expect = 1.9 Identities = 19/89 (21%), Positives = 44/89 (49%), Gaps = 17/89 (19%) Query: 220 QRQRLREQHQIW-----------IREKLKHLEQKEEVADDQVKGLVAEEEACE------E 262 Q +++R+Q ++W +RE+ + ++EE DQ + + +EE E E Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575 Query: 263 RQRWQQEQMVLRFQLEALQEERNTAEQDL 291 ++ W QE+ + + +E++ E+++ Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEM 604 Score = 29.6 bits (65), Expect = 4.2 Identities = 18/71 (25%), Positives = 42/71 (59%), Gaps = 6/71 (8%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++RE+ ++ RE+ K + ++EE+ +Q + + +EE +E Q+E+M + + Sbjct: 581 QEEKMREEERM--REREKKMREEEEMMREQEEKMQEQEEKMQE----QEEKMWEQEEKMQ 634 Query: 280 LQEERNTAEQD 290 QEE+ +++ Sbjct: 635 EQEEKMWEQEE 645 Score = 29.3 bits (64), Expect = 5.5 Identities = 20/98 (20%), Positives = 47/98 (47%) Query: 193 LRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKG 252 L L L +T+T+ L + L+E + + + Q+ ++E + LE+ + + Sbjct: 209 LSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN 268 Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290 + EE +E + +QE+ + + + + ++E EQ+ Sbjct: 269 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE 306 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 39.7 bits (91), Expect = 0.004 Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 10/83 (12%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--------WQ 267 E+ Q +++ EQ +IW R+K K EQ+E++ + K EE+ E+ ++ W+ Sbjct: 477 EMWRQEEKIHEQEEIW-RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535 Query: 268 QEQMVLRFQLEALQEERNTAEQD 290 QE+ + R Q E +EE EQ+ Sbjct: 536 QEEKI-REQEEMWREEEKMHEQE 557 Score = 38.9 bits (89), Expect = 0.007 Identities = 20/82 (24%), Positives = 46/82 (56%), Gaps = 2/82 (2%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 ++ R ++ Q +++R+Q + R++ K EQ+E++ + + K EE+ E+ + W++ Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549 Query: 269 EQMVLRFQLEALQEERNTAEQD 290 E+ + + E + EE EQ+ Sbjct: 550 EEKM--HEQEKIWEEEKRQEQE 569 Score = 38.1 bits (87), Expect = 0.012 Identities = 19/77 (24%), Positives = 46/77 (59%), Gaps = 3/77 (3%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVL 273 +++ Q +++REQ + IRE+ + +++EE +Q + + +EE +E++ W+QE+ + Sbjct: 620 KIQEQEEKIREQEEK-IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678 Query: 274 RFQLEALQEERNTAEQD 290 + + ++E EQ+ Sbjct: 679 EQEKKIREQEEKIREQE 695 Score = 37.4 bits (85), Expect = 0.020 Identities = 17/68 (25%), Positives = 41/68 (60%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 +++ Q +++REQ ++ ++ K EQ+E++ + + K EE+ + ++ ++++ LR Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741 Query: 275 FQLEALQE 282 Q E +QE Sbjct: 742 QQEEKMQE 749 Score = 37.0 bits (84), Expect = 0.026 Identities = 18/64 (28%), Positives = 38/64 (59%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++REQ + ++ K EQ+E + + + K EE+ CE+ ++ Q+++ +R Q E Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732 Query: 280 LQEE 283 + E+ Sbjct: 733 MWEQ 736 Score = 36.6 bits (83), Expect = 0.034 Identities = 22/72 (30%), Positives = 43/72 (59%), Gaps = 1/72 (1%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++REQ + R++ K EQ+E+ + + K EE+ E+ ++ Q+++ +R Q E Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634 Query: 280 LQE-ERNTAEQD 290 ++E E T EQ+ Sbjct: 635 IREQEEMTQEQE 646 Score = 36.6 bits (83), Expect = 0.034 Identities = 20/77 (25%), Positives = 48/77 (62%), Gaps = 3/77 (3%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA-CEERQRWQQEQMVLR 274 ++ Q ++++EQ + IRE+ + + ++EE+ +Q + + +EE CE+ ++ Q+++ + Sbjct: 613 KIREQEEKIQEQEEK-IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671 Query: 275 FQLEALQE-ERNTAEQD 290 Q E ++E E+ EQ+ Sbjct: 672 RQEEKIREQEKKIREQE 688 Score = 36.6 bits (83), Expect = 0.034 Identities = 21/103 (20%), Positives = 54/103 (52%), Gaps = 2/103 (1%) Query: 199 EDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE 258 ++ +T ++G ++ Q ++++EQ + R++ K EQ++++ + + K EE Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697 Query: 259 ACEERQR-WQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300 E+ ++ W+QE+ + Q E +QE+ + +++ V+ Sbjct: 698 MQEQEEKMWEQEEKMCE-QEEKMQEQEEKMRRQEEKMWEQEVR 739 Score = 35.4 bits (80), Expect = 0.076 Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 15/93 (16%) Query: 212 RALRELEAQRQRLREQHQIWIREKLKHLE-----QKEEVADDQVKGLVAEEEACEERQR- 265 R E+ + +++ EQ +IW EK + E Q+E++ + + K EE+ E+ ++ Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600 Query: 266 -------WQQEQMVLRFQLEALQE-ERNTAEQD 290 W+QE+ + R Q E +QE E EQ+ Sbjct: 601 QEQEEKMWKQEEKI-REQEEKIQEQEEKIREQE 632 Score = 34.7 bits (78), Expect = 0.13 Identities = 15/81 (18%), Positives = 45/81 (55%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275 ++ Q +++REQ ++ ++ K EQ+E++ + + K EE + ++ ++++ +R Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686 Query: 276 QLEALQEERNTAEQDLAALYD 296 Q E ++E+ ++ +++ Sbjct: 687 QEEKIREQEEMMQEQEEKMWE 707 Score = 33.5 bits (75), Expect = 0.29 Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 8/85 (9%) Query: 212 RALRELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACE-ERQR 265 R L E +++++REQ + IRE+ K EQ+ ++ + K EE+ E E++ Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453 Query: 266 WQQEQMVLRFQLEALQEERNTAEQD 290 W+QE+ + + E ++EE EQ+ Sbjct: 454 WRQEEKI--HEQEKIREEEKRQEQE 476 Score = 33.5 bits (75), Expect = 0.29 Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 3/71 (4%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++REQ + IRE+ K + ++EE +Q K + EE+ E+ + W+QE+ + Q E Sbjct: 435 QEEKIREQEEK-IREQEKKMWRQEEKIHEQEK-IREEEKRQEQEEMWRQEEKI-HEQEEI 491 Query: 280 LQEERNTAEQD 290 +++ EQ+ Sbjct: 492 WRQKEKMHEQE 502 Score = 33.1 bits (74), Expect = 0.38 Identities = 22/113 (19%), Positives = 55/113 (48%), Gaps = 4/113 (3%) Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIR----EKLKHLEQKEEVADDQVKG 252 LL + LG+ L+ + A+ Q E++++W R ++ K Q+E++ + + K Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316 Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQ 305 EE+ E+ ++ ++++ +R Q E + E+ + +++ + R + Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369 Score = 32.7 bits (73), Expect = 0.49 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 5/78 (6%) Query: 218 EAQRQRLREQHQIWIRE-KLKHLEQ----KEEVADDQVKGLVAEEEACEERQRWQQEQMV 272 E + + R++ +W +E K++ E+ KEE Q + + +EE E + EQ Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405 Query: 273 LRFQLEALQEERNTAEQD 290 +R Q E QEE EQ+ Sbjct: 406 IREQEEKRQEEEKIREQE 423 Score = 32.7 bits (73), Expect = 0.49 Identities = 16/71 (22%), Positives = 39/71 (54%), Gaps = 9/71 (12%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++REQ ++W E+ H ++E++ ++ E+ +E + W+QE+ + + + Sbjct: 536 QEEKIREQEEMWREEEKMH--EQEKIWEE-------EKRQEQEDKMWRQEEKIREQEEKV 586 Query: 280 LQEERNTAEQD 290 ++E EQ+ Sbjct: 587 WRQEEKIREQE 597 Score = 32.0 bits (71), Expect = 0.84 Identities = 19/87 (21%), Positives = 47/87 (54%), Gaps = 4/87 (4%) Query: 208 SQLGRALRELEAQRQRLREQHQ-IWIREKLKHLEQK---EEVADDQVKGLVAEEEACEER 263 +++ R ++ Q +++REQ + +W +E+ H ++K EE +Q + EE+ E+ Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489 Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290 + W+Q++ + + + ++E Q+ Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQE 516 Score = 31.6 bits (70), Expect = 1.1 Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 4/78 (5%) Query: 214 LRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273 +RE E +RQ ++ ++W +E+ K EQ+E++ + + K EE+ E+ + Q+++ + Sbjct: 593 IREQEEKRQE--QEEKMWKQEE-KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649 Query: 274 RFQLEAL-QEERNTAEQD 290 Q E + ++E EQ+ Sbjct: 650 GEQEEKMCEQEEKMQEQE 667 Score = 30.4 bits (67), Expect = 2.5 Identities = 20/71 (28%), Positives = 42/71 (59%), Gaps = 4/71 (5%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC---EERQRWQQEQMV 272 +++ Q +++REQ + IRE+ + + ++EE+ ++ + + +EE EE+ R Q+E M Sbjct: 315 KIQEQEEKIREQEE-KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373 Query: 273 LRFQLEALQEE 283 + + QEE Sbjct: 374 EKEEKMRRQEE 384 Score = 30.4 bits (67), Expect = 2.5 Identities = 16/72 (22%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +++REQ + ++ K +Q+E++ + + K EE+ E+ ++ ++++ + + Q E Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648 Query: 280 L-QEERNTAEQD 290 + ++E EQ+ Sbjct: 649 MGEQEEKMCEQE 660 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 39.7 bits (91), Expect = 0.004 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 11/85 (12%) Query: 217 LEAQRQRLREQHQIW-----------IREKLKHLEQKEEVADDQVKGLVAEEEACEERQR 265 L + +R+REQ ++W IRE+ K + ++EE +Q + + +EE E++ Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427 Query: 266 WQQEQMVLRFQLEALQEERNTAEQD 290 + +Q L Q E L E+ EQ+ Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQE 452 Score = 39.7 bits (91), Expect = 0.004 Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 9/81 (11%) Query: 217 LEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQ 270 L + +R+REQ ++W +RE+ K EQ+++ D + K + EEE ER+ + ++E+ Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK--MREEERMREREKKMREEE 573 Query: 271 MVLRFQLEALQE-ERNTAEQD 290 ++R Q E +QE E EQ+ Sbjct: 574 EMMREQEEKMQEQEEKMREQE 594 Score = 39.3 bits (90), Expect = 0.005 Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 6/93 (6%) Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQV 250 LL T++ ++ R EL Q +++R+Q + +W +RE+ + ++EE Q Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282 Query: 251 KGLVAEEEACEERQRWQQEQMVLRFQLEALQEE 283 K L +E+ E+++ +EQ LR Q E +QE+ Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQ 315 Score = 39.3 bits (90), Expect = 0.005 Identities = 31/135 (22%), Positives = 66/135 (48%), Gaps = 12/135 (8%) Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPL---------RLGLLEDTLTDSGLSQLGRALRE 216 ++Q ++ +W EE R + +R RL E + + ++ R + Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE-EKMRRQEKR 284 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQEQMVLRF 275 L Q + LREQ + +RE+ K EQ+E++ + + K EE+ E+ ++ W+QE+ + Sbjct: 285 LREQEKELREQEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343 Query: 276 QLEALQEERNTAEQD 290 + + ++E+ +Q+ Sbjct: 344 EKQMREQEQKMRDQE 358 Score = 37.4 bits (85), Expect = 0.020 Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 4/78 (5%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC--EERQRWQQEQMV 272 +EL Q + LREQ ++ RE+ + ++++EE +Q + + +EE +E + W+QE+ + Sbjct: 290 KELREQEKELREQKKL--REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347 Query: 273 LRFQLEALQEERNTAEQD 290 + + +E EQD Sbjct: 348 REQEQKMRDQEERMWEQD 365 Score = 37.0 bits (84), Expect = 0.026 Identities = 38/173 (21%), Positives = 79/173 (45%), Gaps = 22/173 (12%) Query: 135 EAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRP-L 193 E + +L + +W + + Y + L + + ++ R T+ + EE + + A L+ L Sbjct: 142 ELQRALSAVSTWHKKADRY---IEELTKERDALSLELYRNTITN--EELKKKNAELQEKL 196 Query: 194 RLGLLEDTLTDSGLSQLGRALR----------------ELEAQRQRLREQHQIWIREKLK 237 RL E + + +L R L E+ Q + LREQ + +++ K Sbjct: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256 Query: 238 HLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290 Q+E + + + K EE+ + +R ++++ LR Q + L+E++ EQ+ Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309 Score = 36.6 bits (83), Expect = 0.034 Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 10/84 (11%) Query: 215 RELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQ-RWQ 267 +++ Q Q++R+Q + +W +REK + + ++E++ + + K + EEE ER+ + + Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK--MQEEERIREREKKMR 402 Query: 268 QEQMVLRFQLEALQ-EERNTAEQD 290 +E+ +R Q E +Q +E N EQ+ Sbjct: 403 EEEETMREQEEKMQKQEENMWEQE 426 Score = 36.2 bits (82), Expect = 0.045 Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 18/89 (20%) Query: 220 QRQRLREQHQIWIREKL------------KHLEQKEEVAD------DQVKGLVAEEEACE 261 Q +++R+Q ++W +EK + EQ+E++ D DQ + + ++E Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517 Query: 262 ERQRWQQEQMVLRFQLEALQEERNTAEQD 290 E++ +EQ + Q E ++EE+ T EQ+ Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQE 546 Score = 35.8 bits (81), Expect = 0.058 Identities = 29/124 (23%), Positives = 60/124 (48%), Gaps = 9/124 (7%) Query: 166 RMQVKQVRPT---LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ-- 220 R Q K++R +W E R + +R + + L + + LRE E + Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ---EKRLREQEKELREQEKELR 300 Query: 221 -RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 +++LREQ + ++ K EQ+E++ + + K EE E+ ++ ++++ +R Q E Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360 Query: 280 LQEE 283 + E+ Sbjct: 361 MWEQ 364 Score = 35.8 bits (81), Expect = 0.058 Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 12/87 (13%) Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQK-----EEVADD-----QVKGLVAEEEACE-ER 263 E E Q+QRL EQ + +W +EK++ E+K E++ D Q K + +E+ E E Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486 Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290 Q W+QE+ + + + +E EQD Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQD 513 Score = 34.3 bits (77), Expect = 0.17 Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 6/77 (7%) Query: 220 QRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273 Q +++REQ + +W + E+ K + ++E+ DQ + + ++E E++ +EQ + Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381 Query: 274 RFQLEALQEERNTAEQD 290 Q E +QEE E++ Sbjct: 382 WEQEEKMQEEERIRERE 398 Score = 34.3 bits (77), Expect = 0.17 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 8/110 (7%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC-EERQRWQQEQMV-- 272 +++ Q +++REQ + ++ K EQ+E++ + K EE+ +E + W QE+M Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727 Query: 273 ---LRFQLEALQEERNTAEQDLA--ALYDLHVQATRAQTHHVLPISGDGG 317 +R Q E +QE E+ + L V + T V P G+ G Sbjct: 728 EERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAG 777 Score = 33.5 bits (75), Expect = 0.29 Identities = 20/75 (26%), Positives = 43/75 (57%), Gaps = 4/75 (5%) Query: 214 LRELEAQRQR---LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQE 269 +RE E R+R +RE+ ++ ++ K EQ+E++ + + K EE+ E+ ++ W+QE Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615 Query: 270 QMVLRFQLEALQEER 284 + + + E +E+ Sbjct: 616 EKMWEQEEEDKMQEQ 630 Score = 33.1 bits (74), Expect = 0.38 Identities = 23/80 (28%), Positives = 48/80 (60%), Gaps = 7/80 (8%) Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEAC---EERQRWQQEQM 271 +++ Q +++ EQ + +W +E+ ++++EE+ +Q + + +EE EE+ R Q+E+M Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662 Query: 272 VLRFQLEALQ-EERNTAEQD 290 R Q E +Q +E EQ+ Sbjct: 663 --REQEEKMQGQEEKMREQE 680 Score = 33.1 bits (74), Expect = 0.38 Identities = 18/74 (24%), Positives = 42/74 (56%), Gaps = 1/74 (1%) Query: 218 EAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQL 277 + + +++EQ ++ ++ K EQ+E++ + + K EE+ E+ ++ Q ++ +R Q Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680 Query: 278 EALQ-EERNTAEQD 290 E +Q +E EQ+ Sbjct: 681 EKMQGQEEKMREQE 694 Score = 32.0 bits (71), Expect = 0.84 Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 2/73 (2%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q ++++EQ + ++ K EQ+E++ + + K EE+ E+ ++ Q ++ +R Q E Sbjct: 637 QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696 Query: 280 L--QEERNTAEQD 290 + QEE+ +++ Sbjct: 697 MRGQEEKMWGQEE 709 Score = 31.6 bits (70), Expect = 1.1 Identities = 24/87 (27%), Positives = 50/87 (57%), Gaps = 9/87 (10%) Query: 212 RALRELEAQRQRLREQHQ-IWIR-EKLKHLEQK----EEVADDQVKGLVAEEEAC--EER 263 R ++L Q ++++EQ + +W + EK++ E+K EE +Q K + +E+ +E Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359 Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290 + W+Q++ LR + E ++E+ EQ+ Sbjct: 360 RMWEQDER-LREKEERMREQEKMWEQE 385 Score = 31.6 bits (70), Expect = 1.1 Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 7/77 (9%) Query: 220 QRQRLREQHQ-IWIREKL-----KHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273 Q +++R+Q Q +W +E+ + L +KEE +Q K EE+ EE++ +QE+ Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550 Query: 274 RFQLEALQEERNTAEQD 290 Q E ++EE E++ Sbjct: 551 D-QEEKMREEERMRERE 566 Score = 31.2 bits (69), Expect = 1.4 Identities = 17/67 (25%), Positives = 42/67 (62%), Gaps = 4/67 (5%) Query: 220 QRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVLRFQ 276 Q ++++EQ + +W +E+ +++E+ +Q + + +EE +E++ W+QE+ +R Q Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK-MREQ 658 Query: 277 LEALQEE 283 E ++E+ Sbjct: 659 EEKMREQ 665 Score = 30.4 bits (67), Expect = 2.5 Identities = 18/76 (23%), Positives = 42/76 (55%), Gaps = 5/76 (6%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275 ++ Q +++REQ EK++ E+K +++++G + EE+ R Q+E+M + Sbjct: 654 KMREQEEKMREQ-----EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708 Query: 276 QLEALQEERNTAEQDL 291 + QEE+ ++++ Sbjct: 709 EKMWGQEEKMWGQEEM 724 Score = 29.6 bits (65), Expect = 4.2 Identities = 18/74 (24%), Positives = 40/74 (54%), Gaps = 3/74 (4%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 + +R+RE+ + E+ EQ+E++ + + K EE+ E+ ++ Q+++ + Q E Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617 Query: 280 L---QEERNTAEQD 290 + +EE EQ+ Sbjct: 618 MWEQEEEDKMQEQE 631 Score = 29.6 bits (65), Expect = 4.2 Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 2/77 (2%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEE--EACEERQRWQQEQMVL 273 +++ Q + + EQ + ++ K EQ+E++ + + K EE + EE+ R Q+E+M Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685 Query: 274 RFQLEALQEERNTAEQD 290 + + QEE+ +++ Sbjct: 686 QEEKMREQEEKMRGQEE 702 Score = 29.3 bits (64), Expect = 5.5 Identities = 20/114 (17%), Positives = 50/114 (43%), Gaps = 4/114 (3%) Query: 177 WDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKL 236 WD E+ R + E+ + ++ ++ Q +++ EQ + ++ Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609 Query: 237 KHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290 K EQ+E++ + + + + E +E W+QE+ + + + ++E EQ+ Sbjct: 610 KMWEQEEKMWEQEEEDKMQE----QEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 39.7 bits (91), Expect = 0.004 Identities = 22/73 (30%), Positives = 47/73 (64%), Gaps = 3/73 (4%) Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA-CEERQRWQQEQMVLRFQLE 278 Q +++REQ + IRE+ + + ++EE+ +Q + + +EE CE+ ++ Q+++ +R Q E Sbjct: 583 QEEKIREQEEK-IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641 Query: 279 ALQE-ERNTAEQD 290 ++E E+ EQ+ Sbjct: 642 KIREQEKKIREQE 654 Score = 38.9 bits (89), Expect = 0.007 Identities = 26/135 (19%), Positives = 67/135 (49%), Gaps = 3/135 (2%) Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLE-DTLTDSGLSQLGRALRELEAQRQRLRE 226 ++++ +W E+ R + +R + E + +T ++G ++ Q ++++E Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631 Query: 227 QHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQEQMVLRFQLEALQEERN 285 Q + R++ K EQ++++ + + K EE E+ ++ W+QE+ + Q E +QE+ Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE-QEEKMQEQEE 690 Query: 286 TAEQDLAALYDLHVQ 300 + +++ V+ Sbjct: 691 KMRRQEEKMWEQEVR 705 Score = 38.9 bits (89), Expect = 0.007 Identities = 22/88 (25%), Positives = 49/88 (55%), Gaps = 2/88 (2%) Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275 ++ Q +++REQ + ++ K EQ+E + + + K EE+ CE+ ++ Q+++ +R Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694 Query: 276 QLEAL--QEERNTAEQDLAALYDLHVQA 301 Q E + QE R +++ + H++A Sbjct: 695 QEEKMWEQEVRLRQQEEKMQEHQEHLEA 722 Score = 38.5 bits (88), Expect = 0.009 Identities = 18/74 (24%), Positives = 43/74 (58%) Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274 +++ Q +++REQ ++ ++ K EQ+E++ + + K EE+ + ++ ++++ LR Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707 Query: 275 FQLEALQEERNTAE 288 Q E +QE + E Sbjct: 708 QQEEKMQEHQEHLE 721 Score = 36.6 bits (83), Expect = 0.034 Identities = 20/83 (24%), Positives = 47/83 (56%), Gaps = 1/83 (1%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 ++ R ++ Q +++R+Q + R++ K +Q+E++ + + K EE+ E+ ++ ++ Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596 Query: 269 EQMVLRFQLEALQE-ERNTAEQD 290 ++ +R Q E QE E EQ+ Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQE 619 Score = 34.3 bits (77), Expect = 0.17 Identities = 20/80 (25%), Positives = 45/80 (56%), Gaps = 1/80 (1%) Query: 212 RALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQM 271 R E+ Q++++ EQ + +++ K Q+E++ D + K EE+ + ++ ++++ Sbjct: 533 REQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592 Query: 272 VLRFQLEALQE-ERNTAEQD 290 +R Q E ++E E T EQ+ Sbjct: 593 KIREQEEKIREQEEMTQEQE 612 Score = 33.9 bits (76), Expect = 0.22 Identities = 28/131 (21%), Positives = 61/131 (46%), Gaps = 7/131 (5%) Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLR 225 ++Q + LW+ + + + + + ++ E+ + + ++ ++ Q +++R Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-EKIREQEEKIREQEEKMR 399 Query: 226 EQHQI-WIRE-KLKHLEQ----KEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q ++ W +E K++ E+ KEE Q + + +EE E + EQ +R Q E Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459 Query: 280 LQEERNTAEQD 290 QEE EQ+ Sbjct: 460 RQEEEKIREQE 470 Score = 33.1 bits (74), Expect = 0.38 Identities = 22/113 (19%), Positives = 55/113 (48%), Gaps = 4/113 (3%) Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIR----EKLKHLEQKEEVADDQVKG 252 LL + LG+ L+ + A+ Q E++++W R ++ K Q+E++ + + K Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377 Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQ 305 EE+ E+ ++ ++++ +R Q E + E+ + +++ + R + Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430 Score = 33.1 bits (74), Expect = 0.38 Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 8/85 (9%) Query: 212 RALRELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQR- 265 R L E +++++REQ + IRE+ K EQ+ ++ + K EE+ E+ ++ Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500 Query: 266 WQQEQMVLRFQLEALQEERNTAEQD 290 W+QE+ + + E ++EE EQ+ Sbjct: 501 WRQEEKI--HEQEKIREEEKRQEQE 523 Score = 32.7 bits (73), Expect = 0.49 Identities = 19/87 (21%), Positives = 47/87 (54%), Gaps = 4/87 (4%) Query: 208 SQLGRALRELEAQRQRLREQHQ-IWIREKLKHLEQK---EEVADDQVKGLVAEEEACEER 263 +++ R ++ Q +++REQ + +W +E+ H ++K EE +Q + EE+ E+ Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536 Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290 + W+Q++ + + + ++E Q+ Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQE 563 Score = 30.8 bits (68), Expect = 1.9 Identities = 21/85 (24%), Positives = 45/85 (52%), Gaps = 10/85 (11%) Query: 216 ELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQ 270 ++ Q +R ++ ++W IRE+ + + ++EE Q + + +E+ EE +R +QE+ Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524 Query: 271 M-----VLRFQLEALQEERNTAEQD 290 M +R Q E +++ EQ+ Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQE 549 >gi|16262452 cingulin [Homo sapiens] Length = 1203 Score = 39.7 bits (91), Expect = 0.004 Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 6/141 (4%) Query: 166 RMQVKQVRPTLWD---AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQ 222 R QV Q+R L A ++ + L L + G + +L +LE+Q Q Sbjct: 996 RDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQ 1055 Query: 223 RLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQE 282 L+E+ Q REK L+ + +VK L + E +ERQ ++ L +++AL+ Sbjct: 1056 LLQERLQAEEREKTV-LQSTNRKLERKVKELSIQIE--DERQHVNDQKDQLSLRVKALKR 1112 Query: 283 ERNTAEQDLAALYDLHVQATR 303 + + AE+++ L L +A R Sbjct: 1113 QVDEAEEEIERLDGLRKKAQR 1133 Score = 32.7 bits (73), Expect = 0.49 Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 40/210 (19%) Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQL----- 210 L LR++ + ++ + L +E+ARA R + + E T L +L Sbjct: 590 LQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQ 649 Query: 211 -----GR----------ALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255 GR A+ +EA R R E+ + +++ L+ L Q E A +VA Sbjct: 650 SQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAK--MVA 707 Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315 E EA QR + LR QEE + + + L + ++ TR Sbjct: 708 EAEATVLGQRRAAVETTLR----ETQEENDEFRRRILGL-EQQLKETR------------ 750 Query: 316 GGLLAGTLEETINLATQNQELQAENQQLQQ 345 GL+ G L + Q L+AE QQL++ Sbjct: 751 -GLVDGGEAVEARLRDKLQRLEAEKQQLEE 779 >gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sapiens] Length = 479 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/131 (25%), Positives = 64/131 (48%), Gaps = 2/131 (1%) Query: 160 LDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA 219 L+ GR++Q + + + + R + RL E+ L + +L L Sbjct: 173 LESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE-ERLCEQEERLCE 231 Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279 Q +RLREQ + +RE+ + L ++EE +Q + L +EE E+++ ++ +L + Sbjct: 232 QEERLREQEE-RLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKL 290 Query: 280 LQEERNTAEQD 290 L++ER EQ+ Sbjct: 291 LEQERRQEEQE 301 Score = 32.0 bits (71), Expect = 0.84 Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 15/91 (16%) Query: 215 RELEAQRQRLR---EQHQIW----------IREKLKHLEQKEEVADDQVKGLVAEEE-AC 260 +ELE+ ++L+ E +Q+ +RE+ + L ++EE +Q + L +EE C Sbjct: 171 KELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLC 230 Query: 261 EERQRWQQEQMVLRFQLEALQE-ERNTAEQD 290 E+ +R ++++ LR Q E L E E EQ+ Sbjct: 231 EQEERLREQEERLREQEERLHEQEERLCEQE 261 Score = 31.2 bits (69), Expect = 1.4 Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 5/115 (4%) Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE-LEAQRQRLREQHQIWIREKLKHL 239 +E R L + L + + LS L R E L Q +RL EQ + + E+ + L Sbjct: 164 DETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEER-LHEQEERL 222 Query: 240 EQKEEVADDQVKGLVAEEEAC---EERQRWQQEQMVLRFQLEALQEERNTAEQDL 291 ++EE +Q + L +EE EER Q+E++ + + QEER ++ L Sbjct: 223 CEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKL 277 >gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] Length = 284 Score = 38.9 bits (89), Expect = 0.007 Identities = 37/159 (23%), Positives = 75/159 (47%), Gaps = 13/159 (8%) Query: 194 RLGLLEDTLTDS--GLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVK 251 +L L E +D+ ++ L R ++ +E + R +E+ + L+ LE+ E+ AD+ + Sbjct: 70 KLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER----LATALQKLEEAEKAADESER 125 Query: 252 GL-VAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVL 310 G+ V E A ++ ++ + ++M L+ +E E+ L L + RA+ + Sbjct: 126 GMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185 Query: 311 PISGDGGLLAGTLEETINLATQN-QELQAENQQLQQGAD 348 L G LEE + T N + L+A +++ + D Sbjct: 186 -----SELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 219 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 38.9 bits (89), Expect = 0.007 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 22/132 (16%) Query: 163 QGRRMQVKQVRPT------LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216 QG+ VKQ+R LW VEE R R E+ + + S+ + L+ Sbjct: 1663 QGKEEAVKQLRKMQAQMKELWREVEETRTSR-----------EEIFSQNRESE--KRLKG 1709 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276 LEA+ RL+E+ R + + + ++E+AD+ G +++ EE+++ + L Sbjct: 1710 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE-- 1767 Query: 277 LEALQEERNTAE 288 E L+EE++ +E Sbjct: 1768 -EELEEEQSNSE 1778 Score = 34.3 bits (77), Expect = 0.17 Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 16/140 (11%) Query: 125 RVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEAR 184 R+L+G++V AE L +V + E + L +G ++VKQ++ L +A EEA Sbjct: 1862 RILSGKLV-RRAEKRLKEVVLQVEEERRVADQLRDQLEKGN-LRVKQLKRQLEEAEEEAS 1919 Query: 185 ARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEE 244 +AG R L+ L + +T+S S RE+ R RLR + ++ + + EE Sbjct: 1920 RAQAGRRRLQREL--EDVTESAESM----NREVTTLRNRLRRGPLTFTTRTVRQVFRLEE 1973 Query: 245 VADDQVKGLVAEEEACEERQ 264 G+ ++EEA EE Q Sbjct: 1974 -------GVASDEEA-EEAQ 1985 Score = 30.4 bits (67), Expect = 2.5 Identities = 18/76 (23%), Positives = 36/76 (47%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 QL + LR+ E +R R+Q + + + K + EE+ +EEA ++ ++ Q Sbjct: 1618 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA 1677 Query: 269 EQMVLRFQLEALQEER 284 + L ++E + R Sbjct: 1678 QMKELWREVEETRTSR 1693 Score = 30.0 bits (66), Expect = 3.2 Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 13/147 (8%) Query: 198 LEDTLT--DSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255 +ED L + G +L + R L+ + L+EQ +EQ++ + + + Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQM----------VEQQQRAEELRAQLGRK 1113 Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315 EEE R + E L++L+E + + L V T+A+ + + Sbjct: 1114 EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQR-RDLGEE 1172 Query: 316 GGLLAGTLEETINLATQNQELQAENQQ 342 L G LE+T++ QEL+++ +Q Sbjct: 1173 LEALRGELEDTLDSTNAQQELRSKREQ 1199 Score = 28.5 bits (62), Expect = 9.3 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 17/138 (12%) Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227 Q++++R L + ARAR + + LE L + QL + RE + +R Sbjct: 1818 QIQELRGRLGEEDAGARARHK----MTIAALESKLAQAE-EQLEQETRERILSGKLVRRA 1872 Query: 228 HQIWIREKLKHLEQKEEVADD----------QVKGLVAE-EEACEERQRWQQEQMVLRFQ 276 + ++E + +E++ VAD +VK L + EEA EE R Q + L+ + Sbjct: 1873 EKR-LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1931 Query: 277 LEALQEERNTAEQDLAAL 294 LE + E + +++ L Sbjct: 1932 LEDVTESAESMNREVTTL 1949 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 38.9 bits (89), Expect = 0.007 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 22/132 (16%) Query: 163 QGRRMQVKQVRPT------LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216 QG+ VKQ+R LW VEE R R E+ + + S+ + L+ Sbjct: 1655 QGKEEAVKQLRKMQAQMKELWREVEETRTSR-----------EEIFSQNRESE--KRLKG 1701 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276 LEA+ RL+E+ R + + + ++E+AD+ G +++ EE+++ + L Sbjct: 1702 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE-- 1759 Query: 277 LEALQEERNTAE 288 E L+EE++ +E Sbjct: 1760 -EELEEEQSNSE 1770 Score = 34.3 bits (77), Expect = 0.17 Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 16/140 (11%) Query: 125 RVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEAR 184 R+L+G++V AE L +V + E + L +G ++VKQ++ L +A EEA Sbjct: 1854 RILSGKLV-RRAEKRLKEVVLQVEEERRVADQLRDQLEKGN-LRVKQLKRQLEEAEEEAS 1911 Query: 185 ARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEE 244 +AG R L+ L + +T+S S RE+ R RLR + ++ + + EE Sbjct: 1912 RAQAGRRRLQREL--EDVTESAESM----NREVTTLRNRLRRGPLTFTTRTVRQVFRLEE 1965 Query: 245 VADDQVKGLVAEEEACEERQ 264 G+ ++EEA EE Q Sbjct: 1966 -------GVASDEEA-EEAQ 1977 Score = 30.4 bits (67), Expect = 2.5 Identities = 18/76 (23%), Positives = 36/76 (47%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 QL + LR+ E +R R+Q + + + K + EE+ +EEA ++ ++ Q Sbjct: 1610 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA 1669 Query: 269 EQMVLRFQLEALQEER 284 + L ++E + R Sbjct: 1670 QMKELWREVEETRTSR 1685 Score = 30.0 bits (66), Expect = 3.2 Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 13/147 (8%) Query: 198 LEDTLT--DSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255 +ED L + G +L + R L+ + L+EQ +EQ++ + + + Sbjct: 1056 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQM----------VEQQQRAEELRAQLGRK 1105 Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315 EEE R + E L++L+E + + L V T+A+ + + Sbjct: 1106 EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQR-RDLGEE 1164 Query: 316 GGLLAGTLEETINLATQNQELQAENQQ 342 L G LE+T++ QEL+++ +Q Sbjct: 1165 LEALRGELEDTLDSTNAQQELRSKREQ 1191 Score = 28.5 bits (62), Expect = 9.3 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 17/138 (12%) Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227 Q++++R L + ARAR + + LE L + QL + RE + +R Sbjct: 1810 QIQELRGRLGEEDAGARARHK----MTIAALESKLAQAE-EQLEQETRERILSGKLVRRA 1864 Query: 228 HQIWIREKLKHLEQKEEVADD----------QVKGLVAE-EEACEERQRWQQEQMVLRFQ 276 + ++E + +E++ VAD +VK L + EEA EE R Q + L+ + Sbjct: 1865 EKR-LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1923 Query: 277 LEALQEERNTAEQDLAAL 294 LE + E + +++ L Sbjct: 1924 LEDVTESAESMNREVTTL 1941 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 38.9 bits (89), Expect = 0.007 Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 22/132 (16%) Query: 163 QGRRMQVKQVRPT------LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216 QG+ VKQ+R LW VEE R R E+ + + S+ + L+ Sbjct: 1696 QGKEEAVKQLRKMQAQMKELWREVEETRTSR-----------EEIFSQNRESE--KRLKG 1742 Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276 LEA+ RL+E+ R + + + ++E+AD+ G +++ EE+++ + L Sbjct: 1743 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE-- 1800 Query: 277 LEALQEERNTAE 288 E L+EE++ +E Sbjct: 1801 -EELEEEQSNSE 1811 Score = 34.3 bits (77), Expect = 0.17 Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 16/140 (11%) Query: 125 RVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEAR 184 R+L+G++V AE L +V + E + L +G ++VKQ++ L +A EEA Sbjct: 1895 RILSGKLV-RRAEKRLKEVVLQVEEERRVADQLRDQLEKGN-LRVKQLKRQLEEAEEEAS 1952 Query: 185 ARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEE 244 +AG R L+ L + +T+S S RE+ R RLR + ++ + + EE Sbjct: 1953 RAQAGRRRLQREL--EDVTESAESM----NREVTTLRNRLRRGPLTFTTRTVRQVFRLEE 2006 Query: 245 VADDQVKGLVAEEEACEERQ 264 G+ ++EEA EE Q Sbjct: 2007 -------GVASDEEA-EEAQ 2018 Score = 30.4 bits (67), Expect = 2.5 Identities = 18/76 (23%), Positives = 36/76 (47%) Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268 QL + LR+ E +R R+Q + + + K + EE+ +EEA ++ ++ Q Sbjct: 1651 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA 1710 Query: 269 EQMVLRFQLEALQEER 284 + L ++E + R Sbjct: 1711 QMKELWREVEETRTSR 1726 Score = 30.0 bits (66), Expect = 3.2 Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 13/147 (8%) Query: 198 LEDTLT--DSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255 +ED L + G +L + R L+ + L+EQ +EQ++ + + + Sbjct: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQM----------VEQQQRAEELRAQLGRK 1146 Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315 EEE R + E L++L+E + + L V T+A+ + + Sbjct: 1147 EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQR-RDLGEE 1205 Query: 316 GGLLAGTLEETINLATQNQELQAENQQ 342 L G LE+T++ QEL+++ +Q Sbjct: 1206 LEALRGELEDTLDSTNAQQELRSKREQ 1232 Score = 28.5 bits (62), Expect = 9.3 Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 17/138 (12%) Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227 Q++++R L + ARAR + + LE L + QL + RE + +R Sbjct: 1851 QIQELRGRLGEEDAGARARHK----MTIAALESKLAQAE-EQLEQETRERILSGKLVRRA 1905 Query: 228 HQIWIREKLKHLEQKEEVADD----------QVKGLVAE-EEACEERQRWQQEQMVLRFQ 276 + ++E + +E++ VAD +VK L + EEA EE R Q + L+ + Sbjct: 1906 EKR-LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1964 Query: 277 LEALQEERNTAEQDLAAL 294 LE + E + +++ L Sbjct: 1965 LEDVTESAESMNREVTTL 1982 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,236,479 Number of Sequences: 37866 Number of extensions: 715120 Number of successful extensions: 5055 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 114 Number of HSP's successfully gapped in prelim test: 315 Number of HSP's that attempted gapping in prelim test: 3129 Number of HSP's gapped (non-prelim): 1545 length of query: 348 length of database: 18,247,518 effective HSP length: 103 effective length of query: 245 effective length of database: 14,347,320 effective search space: 3515093400 effective search space used: 3515093400 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.