Guide to the Human Genome
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Search of human proteins with 239753435

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
         (218 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ...   453   e-128
gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo ...   453   e-128
gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo ...   453   e-128
gi|157168329 formin 1 [Homo sapiens]                                   71   6e-13
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  69   3e-12
gi|153792074 proline rich 12 [Homo sapiens]                            69   3e-12
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas...    67   9e-12
gi|148613878 acrosin precursor [Homo sapiens]                          67   9e-12
gi|52485606 formin-like 2 [Homo sapiens]                               67   1e-11
gi|33356148 formin-like 1 [Homo sapiens]                               65   4e-11
gi|56549694 enabled homolog isoform a [Homo sapiens]                   65   6e-11
gi|39930375 enabled homolog isoform b [Homo sapiens]                   65   6e-11
gi|210032580 SET domain containing 1B [Homo sapiens]                   64   8e-11
gi|145309324 FH2 domain containing 1 [Homo sapiens]                    64   1e-10
gi|150170670 piccolo isoform 2 [Homo sapiens]                          63   2e-10
gi|150378539 piccolo isoform 1 [Homo sapiens]                          63   2e-10
gi|11386183 WAS protein family, member 2 [Homo sapiens]                62   4e-10
gi|160707881 formin 2 [Homo sapiens]                                   61   6e-10
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    61   8e-10
gi|55741677 SET domain containing 1A [Homo sapiens]                    61   8e-10
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    61   8e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 60   1e-09
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    60   1e-09
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                60   1e-09
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                60   1e-09
gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo s...    60   1e-09
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]                     59   3e-09
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]                     59   3e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    59   4e-09
gi|19923345 RNA binding motif protein 12 [Homo sapiens]                59   4e-09

>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
           sapiens]
          Length = 218

 Score =  453 bits (1165), Expect = e-128
 Identities = 218/218 (100%), Positives = 218/218 (100%)

Query: 1   MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP 60
           MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP
Sbjct: 1   MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP 60

Query: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV 120
           PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV
Sbjct: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV 120

Query: 121 TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE 180
           TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE
Sbjct: 121 TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE 180

Query: 181 FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS 218
           FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS
Sbjct: 181 FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS 218


>gi|239747993 PREDICTED: hypothetical protein XP_002346504 [Homo
           sapiens]
          Length = 218

 Score =  453 bits (1165), Expect = e-128
 Identities = 218/218 (100%), Positives = 218/218 (100%)

Query: 1   MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP 60
           MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP
Sbjct: 1   MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP 60

Query: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV 120
           PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV
Sbjct: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV 120

Query: 121 TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE 180
           TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE
Sbjct: 121 TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE 180

Query: 181 FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS 218
           FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS
Sbjct: 181 FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS 218


>gi|239741891 PREDICTED: hypothetical protein XP_002342316 [Homo
           sapiens]
          Length = 218

 Score =  453 bits (1165), Expect = e-128
 Identities = 218/218 (100%), Positives = 218/218 (100%)

Query: 1   MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP 60
           MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP
Sbjct: 1   MEKGKQRDRSYSNFVFFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP 60

Query: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV 120
           PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV
Sbjct: 61  PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSV 120

Query: 121 TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE 180
           TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE
Sbjct: 121 TILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDPLGPCNSSLIALPSISLLLQE 180

Query: 181 FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS 218
           FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS
Sbjct: 181 FKASLASSNEANSINAYPLDLPFWFWGTLIKVAFSNTS 218


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 71.2 bits (173), Expect = 6e-13
 Identities = 36/71 (50%), Positives = 39/71 (54%), Gaps = 4/71 (5%)

Query: 24  PPPPLPPRK----PPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQS 79
           PPPPLPP      PP PP PP P  P PP P  PPP PP P L PP PP     LG + S
Sbjct: 686 PPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSS 745

Query: 80  KVTLFPSISPS 90
           +    P+I PS
Sbjct: 746 QCPRKPAIEPS 756



 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 35/66 (53%), Positives = 36/66 (54%), Gaps = 15/66 (22%)

Query: 24  PPPPLP---------PRKPPRPPKPPRPLPPNPPRPPLPPPR---PPKPPLPPPRP--PK 69
           PPPPLP         P  PP    PP P PP PP PPLPPP    PP PP PPP P  P 
Sbjct: 654 PPPPLPSGLGSLSPAPPMPPVSAGPPLP-PPPPPPPPLPPPSSAGPPPPPPPPPLPNSPA 712

Query: 70  PPSPLG 75
           PP+P G
Sbjct: 713 PPNPGG 718



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 24/52 (46%), Positives = 25/52 (48%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           PPPP     PP  P     L P PP PP+    P  PP PPP P  PPS  G
Sbjct: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAG 697



 Score = 31.6 bits (70), Expect = 0.55
 Identities = 15/35 (42%), Positives = 16/35 (45%)

Query: 41  RPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           + LPP P   P PPP P       P PP PP   G
Sbjct: 643 KALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAG 677


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 35/78 (44%), Positives = 37/78 (47%), Gaps = 14/78 (17%)

Query: 24   PPPPLPPRKPPRPPKP--------------PRPLPPNPPRPPLPPPRPPKPPLPPPRPPK 69
            PPPP PP  PP PP+P              P   PP  P PP PPP PP PP PPP P  
Sbjct: 1959 PPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSA 2018

Query: 70   PPSPLGLAQSKVTLFPSI 87
            PP         + LFPSI
Sbjct: 2019 PPQVQLPVSLDLPLFPSI 2036



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 38/93 (40%), Positives = 42/93 (45%), Gaps = 23/93 (24%)

Query: 21   LWSPPPPLPPRKPPRPPKPPRPLPPNPPRP--------------PL-------PPPRPPK 59
            L+   P  P   PP PP P  PLPP PP+P              PL       PPP PP 
Sbjct: 1947 LYPISPSSPETPPPPPPPP--PLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPP 2004

Query: 60   PPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSM 92
            PP PPP PP PPS     Q  V+L   + PS M
Sbjct: 2005 PPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIM 2037



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 26/63 (41%), Positives = 29/63 (46%), Gaps = 7/63 (11%)

Query: 21   LWSPPPPLPPRKPPRPPKPPRPLPPNPPRPP-------LPPPRPPKPPLPPPRPPKPPSP 73
            L +PPP  PP  PP PP PP P PP P  PP       L  P  P   + P + P  P  
Sbjct: 1990 LQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQ 2049

Query: 74   LGL 76
            L L
Sbjct: 2050 LAL 2052



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 22/103 (21%)

Query: 25   PPPLPPRKPPRPPKP---PRPLPPNPP----RPPL--------PPPRPPKPPLPPPRPPK 69
            P P P +  P+P  P   P+   P+PP    +P L        PP      P P P+PPK
Sbjct: 2350 PKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPK 2409

Query: 70   PPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPL 112
             P  +G         PS S + + S     S + L+++ P  L
Sbjct: 2410 QPQLIGRP-------PSASQTPVPSSPLQISMTSLQNSLPPQL 2445



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 29/80 (36%), Positives = 36/80 (45%), Gaps = 21/80 (26%)

Query: 23   SPPPPLPPRKP----PRPP----KPPRPL---PPNPPR----PPLPPPRPPKPPLPPPRP 67
            SP P  P  KP    P PP    KP  PL     +PP+     P P P+PPK P    RP
Sbjct: 2358 SPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRP 2417

Query: 68   PK------PPSPLGLAQSKV 81
            P       P SPL ++ + +
Sbjct: 2418 PSASQTPVPSSPLQISMTSL 2437



 Score = 34.7 bits (78), Expect = 0.065
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 7/90 (7%)

Query: 39   PPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAAL 98
            P   L   P +P L  P PP PP PPP    P S L   Q++     S    +  +    
Sbjct: 3101 PALSLSSAPTKPLLQTPPPPPPPPPPP----PSSSLSGQQTEQQNKESEKKQTKPNKVKK 3156

Query: 99   ASSSLLKSTKPN---PLEDPVSRSVTILAR 125
                 L++TKP      E+ +S ++++L +
Sbjct: 3157 IKEEELEATKPEKHPKKEEKISSALSVLGK 3186



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 12/20 (60%), Positives = 12/20 (60%)

Query: 36   PPKPPRPLPPNPPRPPLPPP 55
            P KP    PP PP PP PPP
Sbjct: 3109 PTKPLLQTPPPPPPPPPPPP 3128


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 68.9 bits (167), Expect = 3e-12
 Identities = 30/53 (56%), Positives = 33/53 (62%), Gaps = 2/53 (3%)

Query: 24   PPPPLPPRKPPRPPKPP--RPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74
            PPPP PP +P  P  PP   P P +PP PPLPPP PP  P PPP PP   +PL
Sbjct: 1471 PPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPL 1523



 Score = 60.8 bits (146), Expect = 8e-10
 Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 15/92 (16%)

Query: 24   PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTL 83
            PP P P  +PP PP PP+P  P+PP  PL  P P  PP PP  PP PP+           
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPALPSPP--PLVAPTPSSPPPPPLPPPPPPA----------- 1508

Query: 84   FPSISPSSMASLAALASSSLLKSTKPNPLEDP 115
             PS  P    + A LA+    +   P+P EDP
Sbjct: 1509 MPSPPPPPPPAAAPLAAPP-EEPAAPSP-EDP 1538



 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 35/90 (38%), Positives = 38/90 (42%), Gaps = 4/90 (4%)

Query: 25   PPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLF 84
            PPP PP  P   P+PP P PP  P  P PPP     P  PP PP PP P     S     
Sbjct: 1457 PPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP---- 1512

Query: 85   PSISPSSMASLAALASSSLLKSTKPNPLED 114
            P   P + A LAA        S +   L D
Sbjct: 1513 PPPPPPAAAPLAAPPEEPAAPSPEDPELPD 1542



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 30/63 (47%), Positives = 34/63 (53%), Gaps = 6/63 (9%)

Query: 23   SPPPPLPPRKPPRPPKPPRPLPPNPP-RPPLPPPRPPKPPLPPPRPPKPPS--PLGLAQS 79
            SPPPP  P  PP PP  P P PP PP   PL  P P +P  P P  P+ P   PL LA+ 
Sbjct: 1495 SPPPP--PLPPPPPPAMPSPPPPPPPAAAPLAAP-PEEPAAPSPEDPELPDTRPLHLAKK 1551

Query: 80   KVT 82
            + T
Sbjct: 1552 QET 1554



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 26/59 (44%), Positives = 27/59 (45%), Gaps = 11/59 (18%)

Query: 26   PPLPPRKPPRPPKPPRPLPPNP-------PRPPL----PPPRPPKPPLPPPRPPKPPSP 73
            P  PP  P      P PLP  P       P PPL    PPP PP  P P P+PP PP P
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPP 1477



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 26/57 (45%), Positives = 28/57 (49%), Gaps = 12/57 (21%)

Query: 25   PPPLP------PRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKP--PSP 73
            PPPLP          P PP      PP PP  P P P+PP    PPP PP+P  PSP
Sbjct: 1433 PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP----PPPPPPQPALPSP 1485



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 22/50 (44%), Positives = 23/50 (46%), Gaps = 2/50 (4%)

Query: 18   PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRP 67
            P  L  PPPP  P  PP PP    PL   P  P  P P  P+  LP  RP
Sbjct: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPE--LPDTRP 1545



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 30/89 (33%), Positives = 34/89 (38%), Gaps = 36/89 (40%)

Query: 23  SPPPPLPPRKPPRP-----------PKPPRPLPPNPPR--------PPLPPPR------- 56
           SPPPP P  +  +P           P  P  LPP PP+         P P P        
Sbjct: 763 SPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVH 822

Query: 57  ---------PPKPPLPPPRPPKPPSPLGL 76
                     P+PP PPP PP PP PL L
Sbjct: 823 LLEPATRDGAPQPP-PPPPPPPPPMPLQL 850



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 2/43 (4%)

Query: 23   SPPPPLPPRKPPRPPKPPRPLPPNPPR--PPLPPPRPPKPPLP 63
            S PPP  P  PP+P  P +     PP   P    P PP P  P
Sbjct: 1690 SAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 29   PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74
            PP K P PP  P+P  P       PP + P+  +P P  P+ PS L
Sbjct: 1692 PPPKAPAPP--PKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLL 1735



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 33/97 (34%), Positives = 39/97 (40%), Gaps = 14/97 (14%)

Query: 23   SPPPPLPPRKPPRPPKP----PRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQ 78
            +P   L P KPP  P      P  L  + P    PPP PP P  PPP P   P   GL  
Sbjct: 1005 TPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPP--PPPAPASEPKG-GLTS 1061

Query: 79   SKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDP 115
                +F S  P     L   +S  LL+   P P + P
Sbjct: 1062 ---PIFCSTKPK---KLLKTSSFHLLRRRDP-PFQTP 1091



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 22/50 (44%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 20   GLWSPPP--PLPPRKPPRPPKPPRPLPPNP-PRPPLP-PPRPPKPPLPPP 65
            G  +PPP  P PP KP  P K     PP   P   +P PP P KP L  P
Sbjct: 1688 GSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRP 1737



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 23/64 (35%), Positives = 27/64 (42%), Gaps = 10/64 (15%)

Query: 20  GLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPR-PPKPPLPPP---------RPPK 69
           G   PPPP PP  PP P +    L  +   P  P PR  P+  L PP           P 
Sbjct: 831 GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPL 890

Query: 70  PPSP 73
           PP+P
Sbjct: 891 PPAP 894



 Score = 34.7 bits (78), Expect = 0.065
 Identities = 16/33 (48%), Positives = 16/33 (48%)

Query: 26   PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPP 58
            PPL P K   P  P R L P PP  P  P  PP
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 16/42 (38%), Positives = 20/42 (47%)

Query: 26   PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRP 67
            PPL       P  PP+ +PP+ P   L P  P  P +P P P
Sbjct: 1296 PPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPP 1337



 Score = 31.2 bits (69), Expect = 0.71
 Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 15/79 (18%)

Query: 50  PPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLL----- 104
           P   PP  P PP PPP P   P          T F  ++ SS A+ AA  SS  L     
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLP----------TQFNLLASSSAAAAAAEQSSPQLYNFSG 270

Query: 105 KSTKPNPLEDPVSRSVTIL 123
            +  P P E  + R  T++
Sbjct: 271 AAPGPPPPERALPRQDTVI 289



 Score = 31.2 bits (69), Expect = 0.71
 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 6/61 (9%)

Query: 31   RKP-PRPPKPPRPL-----PPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLF 84
            RKP  RPP P R       P +      PPP+ P PP  P  P K  S     Q+  T  
Sbjct: 1664 RKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAM 1723

Query: 85   P 85
            P
Sbjct: 1724 P 1724



 Score = 31.2 bits (69), Expect = 0.71
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 14/61 (22%)

Query: 26   PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP-------PPRP------PKPPS 72
            PP+P R+  +   P      + P P  P P PPKP  P       PP        P+PP+
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSSAPPPKAPAP-PPKPETPEKTTSEKPPEQTPETAMPEPPA 1728

Query: 73   P 73
            P
Sbjct: 1729 P 1729



 Score = 30.8 bits (68), Expect = 0.93
 Identities = 28/97 (28%), Positives = 31/97 (31%), Gaps = 41/97 (42%)

Query: 15  VFFPCGLWSPPPPLPPRKP--PRPPKPPRPLP---------------------------- 44
           V  P GL   P   PP +P  P PP PPR LP                            
Sbjct: 213 VLGPAGLG--PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSG 270

Query: 45  --PNPPRPPLPPPRP-------PKPPLPPPRPPKPPS 72
             P PP P    PR         +P    P PP PP+
Sbjct: 271 AAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPA 307



 Score = 30.8 bits (68), Expect = 0.93
 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 21/116 (18%)

Query: 25   PPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPS-----PLGLAQS 79
            PPP PP   P  P  P        R     P  P   L P +PP+ PS     PLGL QS
Sbjct: 980  PPPGPPAYDPYGPYCPG-------RASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS 1032

Query: 80   KVTLF-------PSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEP 128
                        P   P+  +      +S +  STKP  L    + S  +L R +P
Sbjct: 1033 GPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLK--TSSFHLLRRRDP 1086



 Score = 30.8 bits (68), Expect = 0.93
 Identities = 13/29 (44%), Positives = 15/29 (51%)

Query: 23   SPPPPLPPRKPPRPPKPPRPLPPNPPRPP 51
            SPP  +PP  P R  +P  P  P  P PP
Sbjct: 1308 SPPKSVPPSVPARGLQPQPPATPAVPHPP 1336



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 6/61 (9%)

Query: 31  RKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPS 90
           + PP PP   +   P P    L    P  P + PP PP+      L  S ++  PS SPS
Sbjct: 762 KSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQ------LLPSVLSHAPSPSPS 815

Query: 91  S 91
           +
Sbjct: 816 A 816



 Score = 28.1 bits (61), Expect = 6.0
 Identities = 15/38 (39%), Positives = 17/38 (44%), Gaps = 1/38 (2%)

Query: 18   PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP 55
            P GL    P      PP PP PP P P + P+  L  P
Sbjct: 1026 PLGLIQSGPHQAAPPPPPPPPPP-PAPASEPKGGLTSP 1062


>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
           [Homo sapiens]
          Length = 355

 Score = 67.4 bits (163), Expect = 9e-12
 Identities = 35/72 (48%), Positives = 37/72 (51%), Gaps = 21/72 (29%)

Query: 23  SPPPPLPPRKPPRPP--------------KPPRPLPPNPPR-----PPLPPPRPPKP--P 61
           +PPPP     P RPP               PPRPLPP PP      PP PPP PP P  P
Sbjct: 235 TPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPPSP 294

Query: 62  LPPPRPPKPPSP 73
           LPPP PP PP+P
Sbjct: 295 LPPPPPPPPPTP 306



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 20/39 (51%), Positives = 20/39 (51%), Gaps = 8/39 (20%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPP 61
           SPPPP PP        PP PLPP PP PP  P    K P
Sbjct: 283 SPPPPPPP--------PPSPLPPPPPPPPPTPSSTTKLP 313


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score = 67.4 bits (163), Expect = 9e-12
 Identities = 35/72 (48%), Positives = 37/72 (51%), Gaps = 21/72 (29%)

Query: 23  SPPPPLPPRKPPRPP--------------KPPRPLPPNPPR-----PPLPPPRPPKP--P 61
           +PPPP     P RPP               PPRPLPP PP      PP PPP PP P  P
Sbjct: 301 TPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASP 360

Query: 62  LPPPRPPKPPSP 73
           LPPP PP PP+P
Sbjct: 361 LPPPPPPPPPTP 372



 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 31/55 (56%), Positives = 33/55 (60%), Gaps = 5/55 (9%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQ 78
           PP PLPPR P   P+PP    P+PP PP PPP  P PP PPP PP P S   L Q
Sbjct: 331 PPRPLPPRPPAAQPRPP----PSPPPPP-PPPASPLPPPPPPPPPTPSSTTKLPQ 380


>gi|52485606 formin-like 2 [Homo sapiens]
          Length = 1092

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 30/65 (46%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 27  PLPPRKPPRPPKP--PRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLF 84
           PLPP  PP PP    P  +   P  PP+PPP PP PP PPP PP PP PL    ++    
Sbjct: 525 PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPA 584

Query: 85  PSISP 89
           P ++P
Sbjct: 585 PPLAP 589



 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 33/70 (47%), Positives = 33/70 (47%), Gaps = 20/70 (28%)

Query: 24  PPPPLPPRK---------PPRPPKPPRPLPPNPPRPPLPPPRP-----------PKPPLP 63
           PPPPLPP           P  PP PP P PP PP PP PPP P           P PPL 
Sbjct: 529 PPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLA 588

Query: 64  PPRPPKPPSP 73
           PP P  PP P
Sbjct: 589 PPLPSAPPLP 598



 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 31/68 (45%), Positives = 33/68 (48%), Gaps = 9/68 (13%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNP---------PRPPLPPPRPPKPPLPPPRPPKPPSP 73
           +PP P PP  PP PP PP P PP P         P PPL PP P  PPLP    P     
Sbjct: 549 TPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVVFN 608

Query: 74  LGLAQSKV 81
            GLA  K+
Sbjct: 609 SGLAAVKI 616


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 65.1 bits (157), Expect = 4e-11
 Identities = 38/77 (49%), Positives = 41/77 (53%), Gaps = 15/77 (19%)

Query: 20  GLWSP---PPPLPPRKPPRP------PKPPRP--LPPNPPRPPLPP----PRPPKPPLPP 64
           GL SP   PP  PP+ PP P      P PP P  LPP PP PP PP    P PP PP PP
Sbjct: 550 GLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPP 609

Query: 65  PRPPKPPSPLGLAQSKV 81
           P P  PP  LG   S++
Sbjct: 610 PPPGGPPDALGRRDSEL 626



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 27/56 (48%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP---PPRPPKPPSPLG 75
           +PPPP P    P P + P   PP  P  P  P  PP PPLP   PP PP PP P G
Sbjct: 541 APPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPG 596



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 26/52 (50%), Positives = 28/52 (53%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           P PPLP   PP PP PP P   + P PP PPP PP P  PP    +  S LG
Sbjct: 576 PAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELG 627



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 21/62 (33%), Positives = 24/62 (38%), Gaps = 6/62 (9%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPP------PRPPKPPLPPPRPPKPP 71
           P G  +P P +P   P     P     P    PP PP      P+   P  PP  PP P 
Sbjct: 511 PSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPG 570

Query: 72  SP 73
           SP
Sbjct: 571 SP 572



 Score = 30.8 bits (68), Expect = 0.93
 Identities = 15/45 (33%), Positives = 17/45 (37%)

Query: 27  PLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPP 71
           P+    P     P   +P   P P L P   P P   PP PP  P
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLP 549



 Score = 28.5 bits (62), Expect = 4.6
 Identities = 13/26 (50%), Positives = 13/26 (50%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPL 43
           P G   P PP PP  PP P  PP  L
Sbjct: 594 PPGTDGPVPPPPPPPPPPPGGPPDAL 619



 Score = 28.1 bits (61), Expect = 6.0
 Identities = 14/35 (40%), Positives = 14/35 (40%)

Query: 42  PLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGL 76
           P P  P   P P   P   P P   PP PP   GL
Sbjct: 517 PTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGL 551



 Score = 27.7 bits (60), Expect = 7.9
 Identities = 10/20 (50%), Positives = 11/20 (55%)

Query: 44 PPNPPRPPLPPPRPPKPPLP 63
          P  P  PP   P PPK P+P
Sbjct: 11 PAGPAAPPPKQPAPPKQPMP 30


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 40/96 (41%), Positives = 45/96 (46%), Gaps = 12/96 (12%)

Query: 24  PPPPLPPRK--------PPRPPKPPRPLPPN-PPRPPLPPPRP---PKPPLPPPRPPKPP 71
           PPPPLPP          PP  P PP PLP   PP PP PPP P   P PP PPP PP P 
Sbjct: 315 PPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPA 374

Query: 72  SPLGLAQSKVTLFPSISPSSMASLAALASSSLLKST 107
           S   LA       P    ++  + A L   S ++ T
Sbjct: 375 SGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDT 410



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 41/104 (39%), Positives = 48/104 (46%), Gaps = 20/104 (19%)

Query: 27  PLPPRKPPRPPKPPRPL--------PPNPPRPPL-----PPPRPPKPPLP---PPRPPKP 70
           PL P  PP PP PP P         PP PP PP      PPP PP PPLP   PP PP P
Sbjct: 310 PLAP--PPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP 367

Query: 71  PSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLED 114
           P+P   A        S     +  LAA  + + L+  K + +ED
Sbjct: 368 PAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLR--KVSRMED 409



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 5/54 (9%)

Query: 26  PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP-----PLPPPRPPKPPSPL 74
           P L     P      + +   P  PP PPP PP P      LPPP  P PP PL
Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPL 342


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 40/96 (41%), Positives = 45/96 (46%), Gaps = 12/96 (12%)

Query: 24  PPPPLPPRK--------PPRPPKPPRPLPPN-PPRPPLPPPRP---PKPPLPPPRPPKPP 71
           PPPPLPP          PP  P PP PLP   PP PP PPP P   P PP PPP PP P 
Sbjct: 315 PPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPA 374

Query: 72  SPLGLAQSKVTLFPSISPSSMASLAALASSSLLKST 107
           S   LA       P    ++  + A L   S ++ T
Sbjct: 375 SGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMEDT 410



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 41/104 (39%), Positives = 48/104 (46%), Gaps = 20/104 (19%)

Query: 27  PLPPRKPPRPPKPPRPL--------PPNPPRPPL-----PPPRPPKPPLP---PPRPPKP 70
           PL P  PP PP PP P         PP PP PP      PPP PP PPLP   PP PP P
Sbjct: 310 PLAP--PPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPP 367

Query: 71  PSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLED 114
           P+P   A        S     +  LAA  + + L+  K + +ED
Sbjct: 368 PAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLR--KVSRMED 409



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 21/54 (38%), Positives = 23/54 (42%), Gaps = 5/54 (9%)

Query: 26  PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP-----PLPPPRPPKPPSPL 74
           P L     P      + +   P  PP PPP PP P      LPPP  P PP PL
Sbjct: 289 PGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPL 342


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 64.3 bits (155), Expect = 8e-11
 Identities = 36/69 (52%), Positives = 38/69 (55%), Gaps = 16/69 (23%)

Query: 24  PP--PPLPPRKPPRPPKP----PRPLPPNPPRPP--------LPPPRPPKPPLPPP--RP 67
           PP  PPLPP  PP PP+P    P PLPP PP PP         PPP P  P +PPP   P
Sbjct: 684 PPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILP 743

Query: 68  PKPPSPLGL 76
           P PP P GL
Sbjct: 744 PLPPFPPGL 752



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 32/57 (56%), Positives = 35/57 (61%), Gaps = 7/57 (12%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRP--PLPPPRPPKPPLPPPRPPK---PPSPL 74
           +P  PLPP  P  PP PP P PP PP+P  P+PPP PP PP PPP  P    PP PL
Sbjct: 676 APTLPLPP-PPGFPPLPPPP-PPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPL 730



 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 5/77 (6%)

Query: 21   LWSPPPPLPPRKPPRPPKPPRPLPPNP----PRPPLPPPRPPKPPLPPPRPPKPPSPLGL 76
            L SP PP    +  RPP  P   P +     P PP+  P P +PPLPPPRPP+PPSP   
Sbjct: 1238 LLSPEPPAKEVEA-RPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPE 1296

Query: 77   AQSKVTLFPSISPSSMA 93
             ++     PS+ P  +A
Sbjct: 1297 PETTDASHPSVPPEPLA 1313



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 29/66 (43%), Positives = 32/66 (48%), Gaps = 1/66 (1%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTL 83
           PPP  PP  PP PP PP+P  P PP  P PPP PP P  P    P PP P         +
Sbjct: 683 PPPGFPPLPPPPPPPPPQPGFPMPPPLP-PPPPPPPPAHPAVTVPPPPLPAPPGVPPPPI 741

Query: 84  FPSISP 89
            P + P
Sbjct: 742 LPPLPP 747



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 26/48 (54%), Positives = 27/48 (56%)

Query: 25  PPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPS 72
           P  L P  P  PP    PLPP PP PP  P  P  PPLPPP PP PP+
Sbjct: 672 PSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPA 719



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 32/84 (38%), Positives = 38/84 (45%), Gaps = 2/84 (2%)

Query: 24   PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG-LAQSKVT 82
            P P  PP  PPRPP+PP P PP P       P  P  PL    PP  P   G LA+S+ T
Sbjct: 1275 PLPLQPPLPPPRPPRPPSP-PPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQST 1333

Query: 83   LFPSISPSSMASLAALASSSLLKS 106
                 +P     L+  +S   L S
Sbjct: 1334 ETVPATPGGEPPLSGGSSGLSLSS 1357



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 24/45 (53%), Positives = 25/45 (55%), Gaps = 1/45 (2%)

Query: 18  PCGLWSPPPPLPPRKPP-RPPKPPRPLPPNPPRPPLPPPRPPKPP 61
           P  L  PPPP PP  P    P PP P PP  P PP+ PP PP PP
Sbjct: 706 PPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 26/67 (38%), Positives = 33/67 (49%), Gaps = 3/67 (4%)

Query: 16   FFPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPK--PPLPPPRPPKPPSP 73
            F   G+ +PPPPLPP+ PP PP PP   P   P   L    P +  PP P  R       
Sbjct: 1531 FRNAGIPAPPPPLPPQPPPPPPPPPVE-PTKLPFKELDNQWPSEAIPPGPRGRDEVTEEY 1589

Query: 74   LGLAQSK 80
            + LA+S+
Sbjct: 1590 MELAKSR 1596



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 29/90 (32%), Positives = 33/90 (36%), Gaps = 35/90 (38%)

Query: 18   PCGLWSPPPPLPPRKPPRPPKPP-----------RP------------LPPNPPRPPLPP 54
            P  L S PPP+  RKP RP + P           RP            LP  P  P  P 
Sbjct: 1462 PAPLASCPPPMK-RKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPS 1520

Query: 55   PRPPK-----------PPLPPPRPPKPPSP 73
               P+           P  PPP PP+PP P
Sbjct: 1521 THDPRTVTLDFRNAGIPAPPPPLPPQPPPP 1550



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 23/74 (31%)

Query: 23  SPPP----PLPPRK----PPRPPKPPRPLPPNPP---------------RPPLPPPRPPK 59
           +PPP    P P  K    P + P    P PP  P               R P PPP PP 
Sbjct: 381 TPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPA 440

Query: 60  PPLPPPRPPKPPSP 73
            PL   +P  PP P
Sbjct: 441 EPLAKEKPGTPPGP 454



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 6/57 (10%)

Query: 24  PPPPLPPRKPPRP----PKPPRPLPPNPPRPPLPPPRPPK-PPLPPPRPPKPPSPLG 75
           P  P+     P+P    P       P+   P LP P PP  PPLPPP PP PP   G
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPP-PPPPPPQPG 702



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 31/108 (28%), Positives = 36/108 (33%), Gaps = 58/108 (53%)

Query: 25   PPPLPP--------------RKPPRPPKPP-----------RP-----------LPPNPP 48
            P PLPP              RKP RP + P           RP           L P  P
Sbjct: 1454 PTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQP 1513

Query: 49   RPPL----------------------PPPRPPKPPLPPPRPPKPPSPL 74
            + P+                      PPP PP+PP PPP PP  P+ L
Sbjct: 1514 QTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKL 1561



 Score = 34.3 bits (77), Expect = 0.084
 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 22/110 (20%)

Query: 25  PPPLPPRKPPRPPKPPRPLPPNPP---------RP-----PLPPPRPPKPPL--PPPRPP 68
           PPPLPP +P    KP  P  P PP         RP     P P   P  P L   P  P 
Sbjct: 434 PPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPE 493

Query: 69  KPPSPLG------LAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPL 112
           KP   L       L + +  L     P S   L    S     S++ +PL
Sbjct: 494 KPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPL 543



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 20/57 (35%), Positives = 22/57 (38%), Gaps = 4/57 (7%)

Query: 24  PPPPLPPRKPP----RPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGL 76
           PPPP  P        R     R  P  PP PP  P    KP  PP  PP   + + L
Sbjct: 408 PPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMEL 464



 Score = 32.0 bits (71), Expect = 0.42
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 10/75 (13%)

Query: 4    GKQRDRS--YSNFVFFPCGLWSPPP---PLPPRKPP---RPPKPPRPLPPNPPRP--PLP 53
            G++ +RS   ++ V    GL  P P   PLP   P       + P PLPP  P P    P
Sbjct: 1410 GRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCP 1469

Query: 54   PPRPPKPPLPPPRPP 68
            PP   KP  P   PP
Sbjct: 1470 PPMKRKPGRPRRSPP 1484



 Score = 29.3 bits (64), Expect = 2.7
 Identities = 37/105 (35%), Positives = 42/105 (40%), Gaps = 16/105 (15%)

Query: 7    RDRSYSNFVFFPCG-LWSPPPPLPP-RKPPR--PPKPPRPLPPNPPRP-PLPPPRPPKPP 61
            RD S++     P G L  P  PLP  R+  R  P   P  L    P P PLP P P   P
Sbjct: 1385 RDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALP 1444

Query: 62   L--------PPPRPPKPPSPLGLAQSKVTLFPS---ISPSSMASL 95
                     P P PP  P+PL      +   P     SP SM SL
Sbjct: 1445 AVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSL 1489


>gi|145309324 FH2 domain containing 1 [Homo sapiens]
          Length = 1143

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 28/54 (51%), Positives = 33/54 (61%), Gaps = 4/54 (7%)

Query: 23 SPPPPLPPRKPPRPPKPP----RPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPS 72
          +PPP  PP  PP PP PP    R   P+ P PP PPP P +PP+PPP P  PP+
Sbjct: 29 TPPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIPPPPPGLPPT 82



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 25/49 (51%), Positives = 25/49 (51%), Gaps = 11/49 (22%)

Query: 39 PPRPLPPNPPRPPLPP--------PRPPKPPLPPP---RPPKPPSPLGL 76
          PP P PP PP PP PP        P  P PP PPP    PP PP P GL
Sbjct: 31 PPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEPPIPPPPPGL 79



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 21/40 (52%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 36 PPKPPRPLPPNPPRPPLPPPRP--PKPPLPPPRPPKPPSP 73
          PP PP P PP PP PP    R   P  P PPP PP P  P
Sbjct: 31 PPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLPGEP 70



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 18/38 (47%), Positives = 18/38 (47%), Gaps = 9/38 (23%)

Query: 45 PNPPRPPLPPPRPPKPPL---------PPPRPPKPPSP 73
          P P  PP PPP PP PP           PP PP PP P
Sbjct: 30 PPPAPPPPPPPPPPSPPCSCSREECPSSPPPPPPPPLP 67



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 14/37 (37%), Positives = 17/37 (45%), Gaps = 4/37 (10%)

Query: 53 PPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISP 89
          PPP PP    PPP PP P  P   ++ +    P   P
Sbjct: 30 PPPAPP----PPPPPPPPSPPCSCSREECPSSPPPPP 62


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 21/120 (17%)

Query: 25   PPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLF 84
            PPP     PP PP PP P PP PP PPLPPP  PKP + P +     SP+  A     LF
Sbjct: 2405 PPP-----PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA---TPLF 2456

Query: 85   PSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSSVVSSDRP 144
             ++  +++ + A L S+ L           PV+R  T      P   S   S +V + RP
Sbjct: 2457 DAV--TTLETTAVLRSNGL-----------PVTRICTTAPPPVPPKPSSIPSGLVFTHRP 2503



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 43/121 (35%), Positives = 52/121 (42%), Gaps = 22/121 (18%)

Query: 26  PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPL-------PPPRPPKPPSPLGLAQ 78
           P  PP + P P KPP P  P P +PP   P   KPP        PPP+ P P  P    Q
Sbjct: 466 PTKPPSQLPGPAKPP-PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP-SPQQ 523

Query: 79  SKVTLFPSISPSS---MASLAALASSSLLKSTKP-------NPLEDPVSRSVTILARTEP 128
              T  PS  P S    A   + A  S  +STKP        PL+ P   +V+  A+  P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP---TVSPSAKQPP 580

Query: 129 S 129
           S
Sbjct: 581 S 581



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 31/121 (25%)

Query: 24  PPPPLPPRKPPRPPKPP---------RPLPPNPP-----------------RPPLPPPRP 57
           P P  PP + P P KPP         +P P  PP                 +PP+ PP  
Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358

Query: 58  PKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVS 117
            KPP  P  P KPP     AQ   +  PS       +LA         + +P P + P  
Sbjct: 359 TKPPAQPLGPAKPP-----AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413

Query: 118 R 118
           +
Sbjct: 414 Q 414



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 18/130 (13%)

Query: 25  PPPL---------PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKP----P 71
           PPPL         P  K  +PP+      P PP+ P  P    K P+   +P +P    P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762

Query: 72  SPLGLAQSKVTLFPSISPSSMASLAALASSSLLK--STKPNPLEDPVSRSVTIL---ART 126
           +   ++ S  T  P I  S + S A   ++  LK  S KP+    P    V+     A  
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822

Query: 127 EPSNDSFNVS 136
            P++DS  +S
Sbjct: 823 RPASDSKIIS 832



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 44/145 (30%), Positives = 56/145 (38%), Gaps = 27/145 (18%)

Query: 29   PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKP----PSPLGLA-QSKV 81
            PP  PP+P   P  L       P  PP  PKP +P  P    KP    P P GL+  S +
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542

Query: 82   TL---------FPS----ISPSSMASLAALASS-------SLLKSTKPNPLEDPVSRSVT 121
            TL          PS    +SP S  S    + S         L S    P +   S+++T
Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAIT 2602

Query: 122  ILARTEPSNDSFNVSSVVSSDRPLT 146
                  PS D  +V  V S   P+T
Sbjct: 2603 SWPLGSPSKDLVSVEPVFSVVPPVT 2627



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 12/61 (19%)

Query: 41  RPLPPNPPRPPLPPPRPPKPPLP----------PPRPPKPPSPL--GLAQSKVTLFPSIS 88
           +P  P+P +PP+  P P KPP            P +PP  PS L   LAQ   T+ P + 
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354

Query: 89  P 89
           P
Sbjct: 355 P 355



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 34/112 (30%), Positives = 40/112 (35%), Gaps = 15/112 (13%)

Query: 20  GLWSPPP-PLPPRKPPRPPKP---------PRPLPPNPPRPPLPPPRPPKPPLPPPRPP- 68
           GL SP   P P + P + P P         P         P  PP + P P  PPP+ P 
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG 485

Query: 69  ---KPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVS 117
               PP   G A+       S  P       A  S     STKP P + P S
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGS 536



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 8/118 (6%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPL---PPPRPPKPPSPLGLAQS 79
           S   P P +  P+    P+      P P  PPP   +P L   P  +  +PP    L++ 
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732

Query: 80  KVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSS 137
                PS+   S    A +A     +     P  D VS S    A T+P   S  V S
Sbjct: 733 APPKEPSV--PSEQDKAPVADDKPKQPKMVKPTTDLVSSS---SATTKPDIPSSKVQS 785



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 10/67 (14%)

Query: 18  PCGLWSPPP-PLPPRKPP------RPPKPPRPLPPNPPRPP---LPPPRPPKPPLPPPRP 67
           P G   PP  PL P KPP        P   +P P    +PP     P + P P  PP + 
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414

Query: 68  PKPPSPL 74
              P PL
Sbjct: 415 VGTPKPL 421



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 14/101 (13%)

Query: 32  KPPRPPKPPRPLP--PNPPRPPLPPPRPPK------PPLPPPRPPKPPSPL-GLAQSKVT 82
           KPP   +PP+P+P    P R PL     PK      P     +PP    P+ G  Q+  T
Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT 267

Query: 83  LFPSISPSSMAS-----LAALASSSLLKSTKPNPLEDPVSR 118
               +     AS      A +     +K + P+P + P+ +
Sbjct: 268 DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 16/91 (17%)

Query: 37  PKPP-RPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSP---LGLAQSKVTLFPSISPSSM 92
           PKP  +P+P   P PP P P   +    P + PKP        L    +T  P   P++ 
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923

Query: 93  ------------ASLAALASSSLLKSTKPNP 111
                       AS+ + AS+ +  + +P P
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGP 954



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 16/116 (13%)

Query: 39  PPRPLPPNPPRPP-------LPPPRPPKPPLPPPRPPKPPSPLGLAQSKVT-------LF 84
           P   +PP     P       L    PPK    PP P +P  P GL++S+ T         
Sbjct: 67  PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQP-GLSKSRTTDTFRSEQKL 125

Query: 85  PSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSSVVS 140
           P  SPS++ SL    S + LK    + +       V  L+      + FN   ++S
Sbjct: 126 PGRSPSTI-SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 28/100 (28%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP--------------------RP 57
           P GL  P    P    P    P    PP  P  P  PP                    +P
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394

Query: 58  P---KPPLPPPRPPKPP-----SPLGLAQSKVTLFPSISP 89
           P   K P   P P KPP     +P  LAQ      P+ +P
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 43/120 (35%), Positives = 56/120 (46%), Gaps = 21/120 (17%)

Query: 25   PPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLF 84
            PPP     PP PP PP P PP PP PPLPPP  PKP + P +     SP+  A     LF
Sbjct: 2405 PPP-----PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA---TPLF 2456

Query: 85   PSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSSVVSSDRP 144
             ++  +++ + A L S+ L           PV+R  T      P   S   S +V + RP
Sbjct: 2457 DAV--TTLETTAVLRSNGL-----------PVTRICTTAPPPVPPKPSSIPSGLVFTHRP 2503



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 43/121 (35%), Positives = 52/121 (42%), Gaps = 22/121 (18%)

Query: 26  PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPL-------PPPRPPKPPSPLGLAQ 78
           P  PP + P P KPP P  P P +PP   P   KPP        PPP+ P P  P    Q
Sbjct: 466 PTKPPSQLPGPAKPP-PQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP-SPQQ 523

Query: 79  SKVTLFPSISPSS---MASLAALASSSLLKSTKP-------NPLEDPVSRSVTILARTEP 128
              T  PS  P S    A   + A  S  +STKP        PL+ P   +V+  A+  P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP---TVSPSAKQPP 580

Query: 129 S 129
           S
Sbjct: 581 S 581



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 31/121 (25%)

Query: 24  PPPPLPPRKPPRPPKPP---------RPLPPNPP-----------------RPPLPPPRP 57
           P P  PP + P P KPP         +P P  PP                 +PP+ PP  
Sbjct: 299 PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT 358

Query: 58  PKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVS 117
            KPP  P  P KPP     AQ   +  PS       +LA         + +P P + P  
Sbjct: 359 TKPPAQPLGPAKPP-----AQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413

Query: 118 R 118
           +
Sbjct: 414 Q 414



 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 37/130 (28%), Positives = 54/130 (41%), Gaps = 18/130 (13%)

Query: 25  PPPL---------PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKP----P 71
           PPPL         P  K  +PP+      P PP+ P  P    K P+   +P +P    P
Sbjct: 703 PPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKP 762

Query: 72  SPLGLAQSKVTLFPSISPSSMASLAALASSSLLK--STKPNPLEDPVSRSVTIL---ART 126
           +   ++ S  T  P I  S + S A   ++  LK  S KP+    P    V+     A  
Sbjct: 763 TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822

Query: 127 EPSNDSFNVS 136
            P++DS  +S
Sbjct: 823 RPASDSKIIS 832



 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 44/145 (30%), Positives = 56/145 (38%), Gaps = 27/145 (18%)

Query: 29   PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKP----PSPLGLA-QSKV 81
            PP  PP+P   P  L       P  PP  PKP +P  P    KP    P P GL+  S +
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSM 2542

Query: 82   TL---------FPS----ISPSSMASLAALASS-------SLLKSTKPNPLEDPVSRSVT 121
            TL          PS    +SP S  S    + S         L S    P +   S+++T
Sbjct: 2543 TLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAIT 2602

Query: 122  ILARTEPSNDSFNVSSVVSSDRPLT 146
                  PS D  +V  V S   P+T
Sbjct: 2603 SWPLGSPSKDLVSVEPVFSVVPPVT 2627



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 12/61 (19%)

Query: 41  RPLPPNPPRPPLPPPRPPKPPLP----------PPRPPKPPSPL--GLAQSKVTLFPSIS 88
           +P  P+P +PP+  P P KPP            P +PP  PS L   LAQ   T+ P + 
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQ 354

Query: 89  P 89
           P
Sbjct: 355 P 355



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 34/112 (30%), Positives = 40/112 (35%), Gaps = 15/112 (13%)

Query: 20  GLWSPPP-PLPPRKPPRPPKP---------PRPLPPNPPRPPLPPPRPPKPPLPPPRPP- 68
           GL SP   P P + P + P P         P         P  PP + P P  PPP+ P 
Sbjct: 426 GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPG 485

Query: 69  ---KPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVS 117
               PP   G A+       S  P       A  S     STKP P + P S
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKP-PSQQPGS 536



 Score = 32.7 bits (73), Expect = 0.25
 Identities = 32/118 (27%), Positives = 44/118 (37%), Gaps = 8/118 (6%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPL---PPPRPPKPPSPLGLAQS 79
           S   P P +  P+    P+      P P  PPP   +P L   P  +  +PP    L++ 
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKP 732

Query: 80  KVTLFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSS 137
                PS+   S    A +A     +     P  D VS S    A T+P   S  V S
Sbjct: 733 APPKEPSV--PSEQDKAPVADDKPKQPKMVKPTTDLVSSS---SATTKPDIPSSKVQS 785



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 10/67 (14%)

Query: 18  PCGLWSPPP-PLPPRKPP------RPPKPPRPLPPNPPRPP---LPPPRPPKPPLPPPRP 67
           P G   PP  PL P KPP        P   +P P    +PP     P + P P  PP + 
Sbjct: 355 PPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ 414

Query: 68  PKPPSPL 74
              P PL
Sbjct: 415 VGTPKPL 421



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 27/101 (26%), Positives = 41/101 (40%), Gaps = 14/101 (13%)

Query: 32  KPPRPPKPPRPLP--PNPPRPPLPPPRPPK------PPLPPPRPPKPPSPL-GLAQSKVT 82
           KPP   +PP+P+P    P R PL     PK      P     +PP    P+ G  Q+  T
Sbjct: 208 KPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT 267

Query: 83  LFPSISPSSMAS-----LAALASSSLLKSTKPNPLEDPVSR 118
               +     AS      A +     +K + P+P + P+ +
Sbjct: 268 DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 16/91 (17%)

Query: 37  PKPP-RPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSP---LGLAQSKVTLFPSISPSSM 92
           PKP  +P+P   P PP P P   +    P + PKP        L    +T  P   P++ 
Sbjct: 864 PKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923

Query: 93  ------------ASLAALASSSLLKSTKPNP 111
                       AS+ + AS+ +  + +P P
Sbjct: 924 QETVTGKLFGFGASIFSQASNLISTAGQPGP 954



 Score = 30.0 bits (66), Expect = 1.6
 Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 16/116 (13%)

Query: 39  PPRPLPPNPPRPP-------LPPPRPPKPPLPPPRPPKPPSPLGLAQSKVT-------LF 84
           P   +PP     P       L    PPK    PP P +P  P GL++S+ T         
Sbjct: 67  PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQP-GLSKSRTTDTFRSEQKL 125

Query: 85  PSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSSVVS 140
           P  SPS++ SL    S + LK    + +       V  L+      + FN   ++S
Sbjct: 126 PGRSPSTI-SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLIS 180



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 28/100 (28%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP--------------------RP 57
           P GL  P    P    P    P    PP  P  P  PP                    +P
Sbjct: 335 PSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP 394

Query: 58  P---KPPLPPPRPPKPP-----SPLGLAQSKVTLFPSISP 89
           P   K P   P P KPP     +P  LAQ      P+ +P
Sbjct: 395 PGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 40/108 (37%), Positives = 46/108 (42%), Gaps = 17/108 (15%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPP------LPPP-------RPPKPPLPP 64
           P G  SP  P PP  P  PP P    PP PP PP      LPPP         P PP PP
Sbjct: 338 PVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPP 397

Query: 65  PRPPKPPSPLGLAQSKVTLFPSIS----PSSMASLAALASSSLLKSTK 108
           P P  PP P   A  +  + P +S    P S     + A S LL + +
Sbjct: 398 PPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIR 445



 Score = 62.0 bits (149), Expect = 4e-10
 Identities = 46/130 (35%), Positives = 56/130 (43%), Gaps = 27/130 (20%)

Query: 23  SPPPPLPPRKPPRP----PKPPRPLP----PNPPRPPL--------PPPRPPKPPLPPPR 66
           +PPPP PP  PP P    P PP P P    P  P PPL        PPP PP PP PPP 
Sbjct: 346 TPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPP 405

Query: 67  P-------PKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLK---STKPNPLEDPV 116
           P       P  P PL       +  P++S +    L+A+     L+     +     D V
Sbjct: 406 PFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVV 465

Query: 117 SRSV-TILAR 125
              V TIL+R
Sbjct: 466 GNDVATILSR 475



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 29/59 (49%), Positives = 30/59 (50%), Gaps = 11/59 (18%)

Query: 23  SPPPPLPPRKPPRPPKP-----PRPLPPNPPRPPLPPPRPP----KPPLPPPRPPKPPS 72
           S PPP PP   P  PKP     P P PP PP   +PPP PP     P  PP  PP PPS
Sbjct: 298 SHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPP--PPSPPS 354



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 32/69 (46%), Positives = 34/69 (49%), Gaps = 19/69 (27%)

Query: 21  LWSPPPPLPPRKPPRPPKPPRPLPP----NPPRPPL--------PPPRPPK-PPLP---- 63
           L SPP P P   PP  P PP P PP     PP PP+        PPP PP  PP P    
Sbjct: 306 LGSPPGPKPGFAPP--PAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAA 363

Query: 64  PPRPPKPPS 72
           PP PP PP+
Sbjct: 364 PPPPPPPPA 372



 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 20/40 (50%), Positives = 21/40 (52%)

Query: 36  PPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           PP PP   PP P     PPP PP PP P    P PP P+G
Sbjct: 301 PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVG 340



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 11/62 (17%)

Query: 24  PPPPLPPRKPP--------RPPKPPRPLPPN--PPRPPLPPPRPPKPPL-PPPRPPKPPS 72
           PPPP     P           PK    + P+  PP PPL  P  PKP   PPP PP PP 
Sbjct: 268 PPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPP 327

Query: 73  PL 74
           P+
Sbjct: 328 PM 329


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 61.2 bits (147), Expect = 6e-10
 Identities = 33/70 (47%), Positives = 38/70 (54%), Gaps = 2/70 (2%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVT 82
            PPPPLP    PP PP P   +PP PP P +  P  P PPLPPP    PP PL L  S   
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPL-LPVSGPP 1244

Query: 83   LFPSISPSSM 92
            L P +  S++
Sbjct: 1245 LLPQVGSSTL 1254



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 977  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1036

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1037 PGAGIPPPPPL 1047



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 988  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1047

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1048 PGAGIPPPPPL 1058



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 999  PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1059 PGAGIPPPPPL 1069



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1070 PGAGIPPPPPL 1080



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1081 PGAGIPPPPPL 1091



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1091

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1092 PGAGIPPPPPL 1102



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1103 PGVGIPPPPPL 1113



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1114 PGAGIPPPPPL 1124



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1065 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1125 PGAGIPPPPPL 1135



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1136 PGAGIPPPPPL 1146



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1169 PGAGIPPPPPL 1179



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1180 PGVGIPPPPPL 1190



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 37/85 (43%), Positives = 39/85 (45%), Gaps = 30/85 (35%)

Query: 20   GLWSPPP-------PLPPRK----PPRPPKPPRPLPPNPPRP----PLPPPR-----PPK 59
            G+  PPP       PLPP      PP PP P   +PP PP P    PLPPP      PP 
Sbjct: 919  GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP 978

Query: 60   PPLP----PPRPP------KPPSPL 74
            PPLP    PP PP       PP PL
Sbjct: 979  PPLPGAGIPPPPPLPGAGIPPPPPL 1003



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 31/61 (50%), Positives = 32/61 (52%), Gaps = 14/61 (22%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPPK 69
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1153 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1212

Query: 70   P 70
            P
Sbjct: 1213 P 1213



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1087 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1147 PRVGIPPPPPL 1157



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1098 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1158 PGAGIPPPPPL 1168



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1190

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1191 PGVGIPPPPPL 1201



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 34/71 (47%), Positives = 35/71 (49%), Gaps = 20/71 (28%)

Query: 24   PPPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP- 68
            PPPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP 
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPL 1201

Query: 69   -----KPPSPL 74
                  PP PL
Sbjct: 1202 PGAGIPPPPPL 1212



 Score = 52.0 bits (123), Expect = 4e-07
 Identities = 34/72 (47%), Positives = 34/72 (47%), Gaps = 22/72 (30%)

Query: 24   PPPPLP----PRKPPR-----PPKPPRPLPPNPPRPPLP----PPRPPKP----PLPPPR 66
            PPPPLP    P  PP      PP PP P    PP PPLP    PP PP P    P PPP 
Sbjct: 955  PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1014

Query: 67   -----PPKPPSP 73
                 PP PP P
Sbjct: 1015 PGAGIPPPPPLP 1026



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 35/72 (48%), Positives = 35/72 (48%), Gaps = 22/72 (30%)

Query: 24   PPPPLPPRK-PPRPPKPPR--PLPPN------PPRPPLP----PPRPPKP----PLPPPR 66
            PPPPLP    PP PP P    PLPP       PP PPLP    PP PP P    P PPP 
Sbjct: 944  PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003

Query: 67   -----PPKPPSP 73
                 PP PP P
Sbjct: 1004 PGAGIPPPPPLP 1015



 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 33/70 (47%), Positives = 34/70 (48%), Gaps = 20/70 (28%)

Query: 25   PPPLPPRK-PPRPPKPPRPLPPNPPRP----PLPPPR-----PPKPPLP----PPRPP-- 68
            PPPLP    PP PP P   +PP PP P    P PPP      PP PPLP    PP PP  
Sbjct: 967  PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1026

Query: 69   ----KPPSPL 74
                 PP PL
Sbjct: 1027 GAGIPPPPPL 1036



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 29/58 (50%), Positives = 29/58 (50%), Gaps = 10/58 (17%)

Query: 24  PPPPLP----PRKPPRP-----PKPPRPLPPNPPRPPLPPPR-PPKPPLPPPRPPKPP 71
           PPPPLP    P  PP P     P PP P    PP PPLP    PP PPLP    P PP
Sbjct: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968



 Score = 47.8 bits (112), Expect = 7e-06
 Identities = 35/88 (39%), Positives = 39/88 (44%), Gaps = 35/88 (39%)

Query: 24  PPPPLP------------PRKPP-------RPPKPPRP---LPPNPPRP-----PLPP-- 54
           PPPPLP            P+ PP        PP PP P   +PP PP P     PLPP  
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLP 938

Query: 55  --PRPPKPPLP----PPRPPKPPSPLGL 76
               PP PPLP    PP PP P + + L
Sbjct: 939 GAGIPPPPPLPGAAIPPPPPLPGAGIPL 966



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 34/74 (45%), Positives = 34/74 (45%), Gaps = 26/74 (35%)

Query: 26  PPLPPRKPPR--PPKPP------RPLPP-----NPPRPPLP----PPRPPKP----PLPP 64
           PP PP  P    PP PP       PLPP      PP PPLP    PP PP P    PLPP
Sbjct: 909 PPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968

Query: 65  PR-----PPKPPSP 73
           P      PP PP P
Sbjct: 969 PLPGAGIPPPPPLP 982



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 33/82 (40%), Positives = 36/82 (43%), Gaps = 16/82 (19%)

Query: 24   PPPPLPPRKPPRPPKPPRPLPPN--PPRPPLPPPRPPKPP------LPPPR-----PPKP 70
            PPPPLP    P  P PP P P    PP P LP   PP  P      LP P+     PP  
Sbjct: 1208 PPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPL 1267

Query: 71   PS---PLGLAQSKVTLFPSISP 89
            PS    LG+ Q K +    I P
Sbjct: 1268 PSGLFGLGMNQDKGSRKQPIEP 1289



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 31/81 (38%), Positives = 34/81 (41%), Gaps = 32/81 (39%)

Query: 25  PPPLPPRK------------PPRPPKPPRPLPPNP----PRPP-------LPPPRPPKP- 60
           PPPLP  +            PP PP P   +P  P    P+PP       LPPP PP P 
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917

Query: 61  ---PLPPPRP-----PKPPSP 73
              P PPP P     P PP P
Sbjct: 918 AGIPPPPPLPGAGILPLPPLP 938



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 31/96 (32%), Positives = 36/96 (37%), Gaps = 10/96 (10%)

Query: 24   PPPPLPPRKPPRPPK------PPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLA 77
            PPPPLP    P PP       PP P PP PP     PP P  P   PP  P+  S     
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPT 1256

Query: 78   QSKVTLFPSISPSSMASLAALASSSLLKSTKPNPLE 113
                   P   PS +  L         K ++  P+E
Sbjct: 1257 PQVCGFLPPPLPSGLFGLGMNQD----KGSRKQPIE 1288



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 29/75 (38%), Positives = 31/75 (41%), Gaps = 20/75 (26%)

Query: 19  CGLWSPPP-PLPPRKPPRP-----PKPPRPLPPNPPRPPLPPPRPPKPP-------LPPP 65
           C + SPPP P        P     P PP PLP     P LP    P+PP       LPPP
Sbjct: 853 CNIPSPPPLPCTESSSSMPGLGMVPPPPPPLP-GMTVPTLPSTAIPQPPPLQGTEMLPPP 911

Query: 66  RPP------KPPSPL 74
            PP       PP PL
Sbjct: 912 PPPLPGAGIPPPPPL 926



 Score = 30.8 bits (68), Expect = 0.93
 Identities = 25/71 (35%), Positives = 27/71 (38%), Gaps = 20/71 (28%)

Query: 18   PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPP----LPPPRPP--------------K 59
            P G   PPPPL P     PP  P+      P P     LPPP P               K
Sbjct: 1227 PPGTGIPPPPLLP--VSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRK 1284

Query: 60   PPLPPPRPPKP 70
             P+ P RP KP
Sbjct: 1285 QPIEPCRPMKP 1295


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 60.8 bits (146), Expect = 8e-10
 Identities = 45/130 (34%), Positives = 53/130 (40%), Gaps = 33/130 (25%)

Query: 20  GLWSPPPPLPPRKP---PRPPKPPRP---LPPNPPRPPLPPPRP---------------- 57
           G  +PPPP P R P   P PP P RP   +PP PP    PPP P                
Sbjct: 306 GRGAPPPP-PSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPS 364

Query: 58  --------PKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKP 109
                   P PP PPP PP PP P GL        P+ + +  A L  +   + LK  + 
Sbjct: 365 VLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQ 424

Query: 110 NPLEDPVSRS 119
           N    PVS S
Sbjct: 425 N--SRPVSCS 432



 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 34/81 (41%), Positives = 37/81 (45%), Gaps = 13/81 (16%)

Query: 23  SPPPPLPPR-KPPRPPKPPRPLPPNPP------RPPLPPPRPP--KPPLPPPRPPK---- 69
           +PPPP P R  PP PP PP    P PP       PP PP R P   PP PPP  P     
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVP 335

Query: 70  PPSPLGLAQSKVTLFPSISPS 90
           PP P  +        PS +PS
Sbjct: 336 PPPPNRMYPPPPPALPSSAPS 356



 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 33/77 (42%), Positives = 35/77 (45%), Gaps = 10/77 (12%)

Query: 24  PPPPLPPRK--PPRPPKPPRPLPPNPPR------PPLPPPRPPKPPLPPPRPP--KPPSP 73
           PPPP PP    PP PP   R  PP PP       PP PPP  P   +PPP P    PP P
Sbjct: 288 PPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPP 347

Query: 74  LGLAQSKVTLFPSISPS 90
             L  S  +  P   PS
Sbjct: 348 PALPSSAPSGPPPPPPS 364



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 26/55 (47%), Positives = 28/55 (50%), Gaps = 13/55 (23%)

Query: 31  RKPPRPPKPPRPLPPNPPRPPL---PPPRPPK----PPLPPPR------PPKPPS 72
           R+ P PP P R  PP PP PP    PPP P +    PP PP R      PP PPS
Sbjct: 274 RQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPS 328



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)

Query: 50  PPLPPPRP--PKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSS 91
           PP PPP    P PP PPP    PP P    +      PS +P++
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA 320


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 60.8 bits (146), Expect = 8e-10
 Identities = 31/60 (51%), Positives = 33/60 (55%), Gaps = 11/60 (18%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPP--------NPPRPP--LPPPRPPKPPLPPPRPPKPPSP 73
           PP P PP++PP PP PP P PP         PP  P  L PPRP  PP PP  PP PP P
Sbjct: 595 PPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPP-PPEYPPPPPPP 653



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 25/51 (49%), Positives = 26/51 (50%), Gaps = 10/51 (19%)

Query: 33  PPRPPKPPRPLPPNPPRPPLPPP--------RPPKPP--LPPPRPPKPPSP 73
           PP  P PP+  PP PP PP PPP         PP  P  L PPRP  PP P
Sbjct: 594 PPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPP 644



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 31/106 (29%), Positives = 45/106 (42%), Gaps = 8/106 (7%)

Query: 23   SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVT 82
            SP  PLP ++      P RP  P    PP  P RPP+PP  PP P   P P     S + 
Sbjct: 1103 SPVTPLPEQEA----SPARPAGPTEESPPSAPLRPPEPPAGPPAP--APRPDERPSSPIP 1156

Query: 83   LFPSISPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEP 128
            L P   P       + ++  ++ + +P P   P ++     +R  P
Sbjct: 1157 LLP--PPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAP 1200



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 25/49 (51%), Positives = 26/49 (53%), Gaps = 2/49 (4%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPP-PRPPKPPLPPPRPPKPP 71
           PPPP PP  PP     P   PP+ P   LPP P  P PP  PP PP PP
Sbjct: 607 PPPPPPP-PPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPP 654



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 19/75 (25%)

Query: 18   PCGLWSPPPPLPPRKPPRPPK-PPRPLP-----PNPPRPPLPPPRP-------------P 58
            P G     PP  P +PP PP  PP P P     P+ P P LPPP+              P
Sbjct: 1118 PAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVP 1177

Query: 59   KPPLPPPRPPKPPSP 73
             P  PP  PP+   P
Sbjct: 1178 APEPPPATPPQAKFP 1192



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 19/141 (13%)

Query: 36  PPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKP--------PSPLGLAQSKVTLFPSI 87
           PP     LPP P RP     RPP    PPP PP+P        PSP      +  +  S 
Sbjct: 406 PPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSP-----EREEVRTSP 460

Query: 88  SPSSMASLAALASSSLLKSTKPNPLEDPVSRSVTILARTEPSNDSFNVSSVVSSDRPLTN 147
            P+S A   + A  +  +S  P      +   + +L + + S  SF ++S    +   ++
Sbjct: 461 RPASPARSGSPAPETTNESV-PFAQHSSLDSRIEMLLKEQRSKFSF-LASDTEEEEENSS 518

Query: 148 RVL----DGWLLALGDPLGPC 164
            VL     G  +  G   GPC
Sbjct: 519 MVLGARDTGSEVPSGSGHGPC 539



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 14/23 (60%), Positives = 16/23 (69%)

Query: 46  NPPRPPLPPPRPPKPPLPPPRPP 68
           +PP  P PP +PP PP PPP PP
Sbjct: 593 SPPPAPTPPQQPPPPPPPPPPPP 615



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 18/32 (56%), Positives = 18/32 (56%), Gaps = 1/32 (3%)

Query: 44  PPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           PP  P PP  PP PP PP PPP P     PLG
Sbjct: 594 PPPAPTPPQQPP-PPPPPPPPPPPYLASLPLG 624



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 16/38 (42%), Positives = 18/38 (47%)

Query: 53  PPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPS 90
           PPP P  P  PPP PP PP P     S    +P   P+
Sbjct: 594 PPPAPTPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPA 631



 Score = 35.4 bits (80), Expect = 0.038
 Identities = 19/60 (31%), Positives = 23/60 (38%), Gaps = 13/60 (21%)

Query: 29  PPRKPPRPPKPPRPLPPN-------------PPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           PPR+  R   P  P   N             PP P  P  +  +PP     PP+PP P G
Sbjct: 383 PPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGG 442



 Score = 29.3 bits (64), Expect = 2.7
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 47   PPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFP 85
            P   P   P P + P+P P P + P P  +A S VT  P
Sbjct: 1071 PAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLP 1109



 Score = 28.5 bits (62), Expect = 4.6
 Identities = 21/62 (33%), Positives = 25/62 (40%), Gaps = 9/62 (14%)

Query: 17  FPCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLP-------PPRPPKPPL-PPPRPP 68
           FP    S  PP P R   +  +PP    P PP PP P        P P +  +   PRP 
Sbjct: 405 FPPSYTSYLPPEPSRPTDQDYRPPASEAP-PPEPPEPGGGGGGGGPSPEREEVRTSPRPA 463

Query: 69  KP 70
            P
Sbjct: 464 SP 465



 Score = 28.5 bits (62), Expect = 4.6
 Identities = 14/44 (31%), Positives = 17/44 (38%)

Query: 24   PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRP 67
            P PP P  +PP P   P  L  +P    L  P         P+P
Sbjct: 1308 PTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKP 1351


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 60.8 bits (146), Expect = 8e-10
 Identities = 38/92 (41%), Positives = 44/92 (47%), Gaps = 6/92 (6%)

Query: 23   SPPPPLPPRKPP--RPPK--PPRPLPPNPPRPPLPPPRPPKPPLPPP--RPPKPPSPLGL 76
            +P   LP R PP  +PP   PP   P  PP PP PPP PP+ PLPPP    P PPS    
Sbjct: 1383 APEASLPARSPPSRQPPSGGPPEAPPAQPPPPPPPPPPPPQQPLPPPPNLEPAPPSLGDP 1442

Query: 77   AQSKVTLFPSISPSSMASLAALASSSLLKSTK 108
             +      PS  PS+     A  S S L+  K
Sbjct: 1443 GEPAAHPGPSTGPSTKNENVATLSVSSLERRK 1474


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 43/102 (42%), Positives = 52/102 (50%), Gaps = 12/102 (11%)

Query: 20  GLWSPPPPLPPRKPPRPPKPPRPLPPNPPR--PPLPPPRPPKPPLPPPRPP--KPPSPLG 75
           GL  P P L P  PP P +PP P PP PP   PP PPPR P P LPPP PP   PP P  
Sbjct: 449 GLRGPLPRLLPPGPP-PGRPPGP-PPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRP-- 504

Query: 76  LAQSKVTLFPSISPS--SMASLAALASSSLLKSTKPNPLEDP 115
               +  L P + P+   +   A L +  +L S  PN ++ P
Sbjct: 505 -GMMRPPLVPPLGPAPPGLFPPAPLPNPGVL-SAPPNLIQRP 544



 Score = 57.4 bits (137), Expect = 9e-09
 Identities = 46/121 (38%), Positives = 57/121 (47%), Gaps = 19/121 (15%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPP----------RPPLPPPRPPKPP-LPPPRPPKPPS 72
           PPP LPP  PPR P PPR  PP PP          RPPL PP  P PP L PP P   P 
Sbjct: 474 PPPGLPPGPPPRGP-PPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPG 532

Query: 73  PLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKP---NPLEDPVSRSVTILARTEPS 129
            L  A   +   P    +S A++   A++++  S KP   NP  + ++R V    R    
Sbjct: 533 VLS-APPNLIQRPKADDTSAATIEKKATATI--SAKPQITNPKAE-ITRFVPTALRVRRE 588

Query: 130 N 130
           N
Sbjct: 589 N 589



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 32/61 (52%), Positives = 34/61 (55%), Gaps = 12/61 (19%)

Query: 25  PPPL--PPRKPPRPPKPPRPLPPNPP-------RPP-LPPPRPPKPPLPPPRPP--KPPS 72
           PPPL  PP  P RPP PP  LPP PP       RPP +P  R P P L PP PP  +PP 
Sbjct: 410 PPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG 469

Query: 73  P 73
           P
Sbjct: 470 P 470



 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 33/73 (45%), Positives = 37/73 (50%), Gaps = 7/73 (9%)

Query: 23  SPPPPLPPRKPPRPPKP-PRPLPPNPPRPPLPPPRPPK--PPLPPPRPP---KPPSPLGL 76
           +PP  +PP +   PP P P PL P PP PPL PP PP   PP PPP  P   +PP   GL
Sbjct: 392 APPQSVPPSQIQAPPMPGPPPLGP-PPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGL 450

Query: 77  AQSKVTLFPSISP 89
                 L P   P
Sbjct: 451 RGPLPRLLPPGPP 463



 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 30/73 (41%), Positives = 32/73 (43%), Gaps = 19/73 (26%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP------RPP------------K 59
           P  + +PP P PP   P P  P RP  P    PP PPP      RPP             
Sbjct: 399 PSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLL 458

Query: 60  PPLPPP-RPPKPP 71
           PP PPP RPP PP
Sbjct: 459 PPGPPPGRPPGPP 471



 Score = 32.0 bits (71), Expect = 0.42
 Identities = 23/56 (41%), Positives = 24/56 (42%), Gaps = 15/56 (26%)

Query: 27  PLPPRKPPRPPKPPRPLPPNPPR------------PPLPPPRPPKPPLPPPRPPKP 70
           PLP  +PP   K      P P R            P LPP R  KPP PPP PP P
Sbjct: 157 PLPGAQPPSILKKTSAYGP-PTRAVSILPLLGHGVPRLPPGR--KPPGPPPGPPPP 209


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 29/59 (49%), Positives = 33/59 (55%), Gaps = 7/59 (11%)

Query: 24  PPPPLPPRKP-------PRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           PPP L P +P       P PP PP P+P   P P  PPP+   PP P P PP+PP PLG
Sbjct: 274 PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLG 332



 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 31/60 (51%), Positives = 35/60 (58%), Gaps = 5/60 (8%)

Query: 18  PCGLWSPPPPLPP-RKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPL--PPPRPPKPPSPL 74
           P G   PPPP P  + PPRPP  P P PP PP PP PP +   PPL  PP R  +PP P+
Sbjct: 220 PAGPGGPPPPFPAGQTPPRPPLGP-PGPPGPPGPP-PPGQVLPPPLAGPPNRGDRPPPPV 277



 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 30/67 (44%), Positives = 34/67 (50%), Gaps = 5/67 (7%)

Query: 24  PPPPL-----PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQ 78
           PPPP+     P  +PP  P PP P PP P   P P P PP+   PPP  P PP P G   
Sbjct: 273 PPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLG 332

Query: 79  SKVTLFP 85
             +TL P
Sbjct: 333 PPLTLAP 339



 Score = 54.3 bits (129), Expect = 8e-08
 Identities = 34/77 (44%), Positives = 38/77 (49%), Gaps = 10/77 (12%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPK---PPL---PPPRPPKPP--SPLG 75
           PPPP+P   PP  P PP+  PP PP P   PPRPP    PPL   PPP  P PP  +P  
Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPPPPPGPF--PPRPPGPLGPPLTLAPPPHLPGPPPGAPPP 353

Query: 76  LAQSKVTLFPSISPSSM 92
                   FP  + S M
Sbjct: 354 APHVNPAFFPPPTNSGM 370



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 26/50 (52%), Positives = 26/50 (52%), Gaps = 4/50 (8%)

Query: 25  PPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74
           P P  P  PP    PP P    PPRPPL PP PP PP PPP     P PL
Sbjct: 218 PGPAGPGGPP----PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPL 263



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 30  PRKPPRPPKPPRPLPPNPPRPPLPPPR-PPKPPLPPPRPPKPPSP 73
           P   P   + P P  P  P PP P  + PP+PPL PP PP PP P
Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGP 252



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 25/56 (44%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQS 79
           PP P PPR PP P  PP  L P P  P  PP  PP  P   P    PP+  G+  S
Sbjct: 319 PPGPFPPR-PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTS 373



 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 31/77 (40%), Positives = 33/77 (42%), Gaps = 25/77 (32%)

Query: 24  PPPPL---PPRKPPRPPKPPRPL--------PPNPPRPP--LPPPRPPKPP--LPPP--- 65
           PPPP    PP   P PP+PP PL        PP+ P PP   PPP P   P   PPP   
Sbjct: 309 PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368

Query: 66  -------RPPKPPSPLG 75
                  R P P  P G
Sbjct: 369 GMPTSDSRGPPPTDPYG 385



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 17/34 (50%), Positives = 17/34 (50%)

Query: 42  PLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPLG 75
           P P  P  PP P P    PP PP  PP PP P G
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPG 251



 Score = 29.3 bits (64), Expect = 2.7
 Identities = 20/51 (39%), Positives = 21/51 (41%), Gaps = 5/51 (9%)

Query: 23  SPPPPLP---PRKPPRPP--KPPRPLPPNPPRPPLPPPRPPKPPLPPPRPP 68
           +PPP LP   P  PP  P   P    PP     P    R P P  P  RPP
Sbjct: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPP 388


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 35/70 (50%), Positives = 35/70 (50%), Gaps = 19/70 (27%)

Query: 24  PPPPLPP----RKPPRPPKPPRP------LPPNPPRPPLP---PPRPPKPPLPPPRP--- 67
           PPPPL P      PP PP PP P      LP  PP PPLP      PP PPLPPP P   
Sbjct: 425 PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSC 484

Query: 68  ---PKPPSPL 74
              P PP PL
Sbjct: 485 EFLPPPPPPL 494



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 35/85 (41%), Positives = 35/85 (41%), Gaps = 34/85 (40%)

Query: 24  PPPPLPPRKP-----PRPPKPPRPLPP---------------------NPPRPPLPPPRP 57
           PPPP PP  P     P PP PP PLP                       PP PPLPPP P
Sbjct: 422 PPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLP 481

Query: 58  PK----PPLPPPRP----PKPPSPL 74
                 PP PPP P    P PP PL
Sbjct: 482 GSCEFLPPPPPPLPGLGCPPPPPPL 506



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 32/64 (50%), Positives = 33/64 (51%), Gaps = 14/64 (21%)

Query: 24  PPPPLP---PRKPPRPPKPPRPLPPN-----PPRPPLP-----PPRPPKPPLPPPRPPKP 70
           PPPPLP      PP PP PP PLP +     PP PPLP     PP PP  P     PP P
Sbjct: 459 PPPPLPGLGAMAPPAPPLPP-PLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPP 517

Query: 71  PSPL 74
           P PL
Sbjct: 518 PPPL 521



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 30/70 (42%), Positives = 31/70 (44%), Gaps = 21/70 (30%)

Query: 23  SPPPPLPPRKPPRPPKPPRPL--------PPNPPRPPLP-------PPRPPKPPLP---- 63
           S P  L  +    PP PP PL        PP PP PPLP       P  PP PPLP    
Sbjct: 409 SQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGA 468

Query: 64  --PPRPPKPP 71
             PP PP PP
Sbjct: 469 MAPPAPPLPP 478



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 27/59 (45%), Positives = 28/59 (47%), Gaps = 5/59 (8%)

Query: 20  GLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP-----PPRPPKPPSP 73
           GL +  PP PP  PP P       PP PP P L  P PP P LP     PP PP P  P
Sbjct: 465 GLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLP 523



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 26/63 (41%), Positives = 28/63 (44%), Gaps = 5/63 (7%)

Query: 34  PRPPKPPRPLPPNPPRPPLPPPRPPKPPLP----PPRPPKPPSP-LGLAQSKVTLFPSIS 88
           P PP PP  LP +   PP PPP PP P +     P  PP PP P LG         P   
Sbjct: 421 PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPL 480

Query: 89  PSS 91
           P S
Sbjct: 481 PGS 483



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 13/92 (14%)

Query: 40  PRPLPPNPPRPPLPPPRPPKP---PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLA 96
           PR L      PP PPP P  P     PPP PP PP P   A++  T  P   P  +  L 
Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPP---PPPLPGLG 467

Query: 97  ALASSSLLKSTKPNPLEDPVSRSVTILARTEP 128
           A+A  +        PL  P+  S   L    P
Sbjct: 468 AMAPPA-------PPLPPPLPGSCEFLPPPPP 492



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 15/29 (51%), Positives = 16/29 (55%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPL 52
           PPPPL P     PP PP PL P    PP+
Sbjct: 502 PPPPLLPGMGWGPPPPPPPLLPCTCSPPV 530



 Score = 32.0 bits (71), Expect = 0.42
 Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 10/55 (18%)

Query: 19  CGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSP 73
           C    PPP         PP P    PP PP P LP      PP PPP  P   SP
Sbjct: 484 CEFLPPPP---------PPLPGLGCPP-PPPPLLPGMGWGPPPPPPPLLPCTCSP 528


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 35/70 (50%), Positives = 35/70 (50%), Gaps = 19/70 (27%)

Query: 24  PPPPLPP----RKPPRPPKPPRP------LPPNPPRPPLP---PPRPPKPPLPPPRP--- 67
           PPPPL P      PP PP PP P      LP  PP PPLP      PP PPLPPP P   
Sbjct: 425 PPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSC 484

Query: 68  ---PKPPSPL 74
              P PP PL
Sbjct: 485 EFLPPPPPPL 494



 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 35/85 (41%), Positives = 35/85 (41%), Gaps = 34/85 (40%)

Query: 24  PPPPLPPRKP-----PRPPKPPRPLPP---------------------NPPRPPLPPPRP 57
           PPPP PP  P     P PP PP PLP                       PP PPLPPP P
Sbjct: 422 PPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLP 481

Query: 58  PK----PPLPPPRP----PKPPSPL 74
                 PP PPP P    P PP PL
Sbjct: 482 GSCEFLPPPPPPLPGLGCPPPPPPL 506



 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 32/64 (50%), Positives = 33/64 (51%), Gaps = 14/64 (21%)

Query: 24  PPPPLP---PRKPPRPPKPPRPLPPN-----PPRPPLP-----PPRPPKPPLPPPRPPKP 70
           PPPPLP      PP PP PP PLP +     PP PPLP     PP PP  P     PP P
Sbjct: 459 PPPPLPGLGAMAPPAPPLPP-PLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPP 517

Query: 71  PSPL 74
           P PL
Sbjct: 518 PPPL 521



 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 30/70 (42%), Positives = 31/70 (44%), Gaps = 21/70 (30%)

Query: 23  SPPPPLPPRKPPRPPKPPRPL--------PPNPPRPPLP-------PPRPPKPPLP---- 63
           S P  L  +    PP PP PL        PP PP PPLP       P  PP PPLP    
Sbjct: 409 SQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGA 468

Query: 64  --PPRPPKPP 71
             PP PP PP
Sbjct: 469 MAPPAPPLPP 478



 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 27/59 (45%), Positives = 28/59 (47%), Gaps = 5/59 (8%)

Query: 20  GLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP-----PPRPPKPPSP 73
           GL +  PP PP  PP P       PP PP P L  P PP P LP     PP PP P  P
Sbjct: 465 GLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLP 523



 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 26/63 (41%), Positives = 28/63 (44%), Gaps = 5/63 (7%)

Query: 34  PRPPKPPRPLPPNPPRPPLPPPRPPKPPLP----PPRPPKPPSP-LGLAQSKVTLFPSIS 88
           P PP PP  LP +   PP PPP PP P +     P  PP PP P LG         P   
Sbjct: 421 PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPL 480

Query: 89  PSS 91
           P S
Sbjct: 481 PGS 483



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/92 (33%), Positives = 37/92 (40%), Gaps = 13/92 (14%)

Query: 40  PRPLPPNPPRPPLPPPRPPKP---PLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMASLA 96
           PR L      PP PPP P  P     PPP PP PP P   A++  T  P   P  +  L 
Sbjct: 411 PRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPP---PPPLPGLG 467

Query: 97  ALASSSLLKSTKPNPLEDPVSRSVTILARTEP 128
           A+A  +        PL  P+  S   L    P
Sbjct: 468 AMAPPA-------PPLPPPLPGSCEFLPPPPP 492



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 15/29 (51%), Positives = 16/29 (55%)

Query: 24  PPPPLPPRKPPRPPKPPRPLPPNPPRPPL 52
           PPPPL P     PP PP PL P    PP+
Sbjct: 502 PPPPLLPGMGWGPPPPPPPLLPCTCSPPV 530



 Score = 32.0 bits (71), Expect = 0.42
 Identities = 22/55 (40%), Positives = 22/55 (40%), Gaps = 10/55 (18%)

Query: 19  CGLWSPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSP 73
           C    PPP         PP P    PP PP P LP      PP PPP  P   SP
Sbjct: 484 CEFLPPPP---------PPLPGLGCPP-PPPPLLPGMGWGPPPPPPPLLPCTCSP 528


>gi|14149904 anthrax toxin receptor 1 isoform 1 precursor [Homo
           sapiens]
          Length = 564

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 5/55 (9%)

Query: 18  PCGLWSPPPPLP--PRKPPRPPKPPRPLPPN--PPRPPLPPP-RPPKPPLPPPRP 67
           P  +++PPPP P  P  PP  P PP P PP+  PP P  PPP R P P  PPPRP
Sbjct: 508 PAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPSRPPPRP 562



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 25/53 (47%), Positives = 27/53 (50%), Gaps = 3/53 (5%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPP---RPPKPPLPPPRPPKPPS 72
           S PPP P   PP P     P PP+ P PP+P P    PP P  PPP    PPS
Sbjct: 504 SSPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRAPPPS 556



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 17/35 (48%), Positives = 17/35 (48%)

Query: 40  PRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPPSPL 74
           P P P   P PP P   PP P  P P  P PPS L
Sbjct: 506 PPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTL 540



 Score = 36.2 bits (82), Expect = 0.022
 Identities = 17/48 (35%), Positives = 22/48 (45%)

Query: 46  NPPRPPLPPPRPPKPPLPPPRPPKPPSPLGLAQSKVTLFPSISPSSMA 93
           +PP  P+  P PP P  PPP P  P  P+    S +   P   P + A
Sbjct: 505 SPPPAPIYTPPPPAPHCPPPPPSAPTPPIPSPPSTLPPPPQAPPPNRA 552



 Score = 30.8 bits (68), Expect = 0.93
 Identities = 17/44 (38%), Positives = 20/44 (45%), Gaps = 2/44 (4%)

Query: 32  KPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSP 73
           K  +P K P     +   PP  P   P PP P  PP PP  P+P
Sbjct: 488 KNNQPAKYPLNNAYHTSSPPPAPIYTPPPPAPHCPPPPPSAPTP 531


>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
          Length = 1096

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 35/84 (41%), Positives = 42/84 (50%), Gaps = 10/84 (11%)

Query: 1   MEKGKQRDRSYSNFVFFPCGLWSPP--PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPP 58
           +E   Q+ R+ +  +    G+  PP  PPLP   PP PP  P PLP   P PP PPP P 
Sbjct: 528 LEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAP-PLPGGAPLPPPPPPLPG 586

Query: 59  KPPLPPPRP-------PKPPSPLG 75
              +PPP P       P PP PLG
Sbjct: 587 MMGIPPPPPPPLLFGGPPPPPPLG 610



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 29/65 (44%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 24  PPPPLPPRKPPRPPKPPRP----LPPNPPRPPL---PPPRPPKPPLPPPRPPKPPSPLGL 76
           P PPLP   P  PP PP P    +PP PP P L   PPP PP   +PPP       P G+
Sbjct: 567 PAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGM 626

Query: 77  AQSKV 81
            Q K+
Sbjct: 627 KQKKM 631



 Score = 28.5 bits (62), Expect = 4.6
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 20  GLWSPPPPLPPRKPPRPPKPPRPLPPNPPRP 50
           G+   PPP PP      P PP PL   PP P
Sbjct: 586 GMMGIPPPPPPPLLFGGPPPPPPLGGVPPPP 616


>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
          Length = 1101

 Score = 58.9 bits (141), Expect = 3e-09
 Identities = 35/84 (41%), Positives = 42/84 (50%), Gaps = 10/84 (11%)

Query: 1   MEKGKQRDRSYSNFVFFPCGLWSPP--PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPP 58
           +E   Q+ R+ +  +    G+  PP  PPLP   PP PP  P PLP   P PP PPP P 
Sbjct: 528 LEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAP-PLPGGAPLPPPPPPLPG 586

Query: 59  KPPLPPPRP-------PKPPSPLG 75
              +PPP P       P PP PLG
Sbjct: 587 MMGIPPPPPPPLLFGGPPPPPPLG 610



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 29/65 (44%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 24  PPPPLPPRKPPRPPKPPRP----LPPNPPRPPL---PPPRPPKPPLPPPRPPKPPSPLGL 76
           P PPLP   P  PP PP P    +PP PP P L   PPP PP   +PPP       P G+
Sbjct: 567 PAPPLPGGAPLPPPPPPLPGMMGIPPPPPPPLLFGGPPPPPPLGGVPPPPGISLNLPYGM 626

Query: 77  AQSKV 81
            Q K+
Sbjct: 627 KQKKM 631



 Score = 28.5 bits (62), Expect = 4.6
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 20  GLWSPPPPLPPRKPPRPPKPPRPLPPNPPRP 50
           G+   PPP PP      P PP PL   PP P
Sbjct: 586 GMMGIPPPPPPPLLFGGPPPPPPLGGVPPPP 616


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 34/83 (40%), Positives = 38/83 (45%), Gaps = 9/83 (10%)

Query: 24  PPPPL-PPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPP--------KPPSPL 74
           PPPPL PP   P PP PP    P PP  P PPP    PPLP P PP         PP  +
Sbjct: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461

Query: 75  GLAQSKVTLFPSISPSSMASLAA 97
               S+    P ++PS  A   A
Sbjct: 462 PATCSRKRGRPPLTPSQRAEREA 484



 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 32/90 (35%), Positives = 39/90 (43%), Gaps = 26/90 (28%)

Query: 23  SPPPPLPPRKPPRPPKPPRPLPPNPPRPPLP---------------------PPRPPKPP 61
           SPP P  P   P PP+   P PP+ P  PLP                     PP PP PP
Sbjct: 570 SPPVPQEPAPVPSPPR--APTPPSTP-VPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626

Query: 62  LPPPRPPKPPSPLGLAQSKVTL-FPSISPS 90
            PPP P  PP+P   ++  + L  P  +PS
Sbjct: 627 -PPPAPSPPPAPATSSRRPLLLRAPQFTPS 655



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 21/45 (46%), Positives = 22/45 (48%), Gaps = 4/45 (8%)

Query: 34  PRPPKPPRPLPPNPPRPPLPPPRPPKPPL----PPPRPPKPPSPL 74
           P   K    LPP P  PP P P PP PP     PPP  P PP P+
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPV 436



 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 19/44 (43%), Positives = 21/44 (47%)

Query: 28  LPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPPKPP 71
           +P  +      PP PL P  P PP P P P   P PP  PP PP
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPP 434



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 27/91 (29%), Positives = 33/91 (36%), Gaps = 25/91 (27%)

Query: 24  PPPPLPPRKPPRPPKPP-------RPLPPNPPR-----------------PPLPPPRPPK 59
           PPPP  P  PP P  PP       RPL    P+                 PPL  P  P+
Sbjct: 619 PPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE 678

Query: 60  P-PLPPPRPPKPPSPLGLAQSKVTLFPSISP 89
           P P P    P  P P  + ++     P  +P
Sbjct: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAP 709



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 37/137 (27%), Positives = 45/137 (32%), Gaps = 46/137 (33%)

Query: 22   WSPPPP----LPPRKPPRPPKPP---------------------RPLPPNPPRPPLPPPR 56
            W P  P    L     P PPKP                       P+PP   +PPLPP  
Sbjct: 2165 WLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTI 2224

Query: 57   PPKPP----LPP--------------PRPPKPPSPLGLAQSKVTLFPSISPSSMASLAAL 98
             P  P    LPP              P PP PP PL L  S     P+  P     +  +
Sbjct: 2225 SPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSS---GPASPPRQAIRVKRV 2281

Query: 99   ASSSLLKSTKPNPLEDP 115
            ++ S      P P + P
Sbjct: 2282 STFSGRSPPAPPPYKAP 2298



 Score = 37.0 bits (84), Expect = 0.013
 Identities = 37/128 (28%), Positives = 44/128 (34%), Gaps = 31/128 (24%)

Query: 18  PCGLWSPPPPLPPRKPPRPPKPPRPL--------PPNPP--------RPPLPP------- 54
           P  L  PPPP P   PP P  PP P         PP  P        RPPL P       
Sbjct: 425 PPPLCPPPPP-PVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAERE 483

Query: 55  -----PRPPKPPLPPPRPPK--PPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKST 107
                P    PP P P      PP        K T F       +  + +  SS ++K+ 
Sbjct: 484 AARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTP 543

Query: 108 KPNPLEDP 115
           +    EDP
Sbjct: 544 RRFMDEDP 551



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 26/81 (32%), Positives = 29/81 (35%), Gaps = 40/81 (49%)

Query: 33  PPRPPK---------PPRPLPPNPPRP-PLP-PPRPPKPPL------------------- 62
           PP+PPK         P    PP P  P P+P PPR P PP                    
Sbjct: 551 PPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFR 610

Query: 63  ----------PPPRPPKPPSP 73
                     PPP PP PP+P
Sbjct: 611 WTSLTRELPPPPPAPPPPPAP 631



 Score = 35.8 bits (81), Expect = 0.029
 Identities = 32/100 (32%), Positives = 39/100 (39%), Gaps = 18/100 (18%)

Query: 24   PPPPLPPRKP-PRPPKPPRPLPPNPPRPPLPPPRPPKP------------PLPPPRP-PK 69
            P PP   R+P P  P+PP     +PP    P  R P P             L PP P P 
Sbjct: 1907 PAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPS 1966

Query: 70   PPSPLGLAQSKVTLFPSISPSSMASLAALASSSLLKSTKP 109
            PP P  L       F  +   S  S A L  ++ L  T+P
Sbjct: 1967 PPPPEDLGPD----FEDMEVVSGLSAADLDFAASLLGTEP 2002



 Score = 33.9 bits (76), Expect = 0.11
 Identities = 21/58 (36%), Positives = 28/58 (48%), Gaps = 16/58 (27%)

Query: 39  PPRPLPPNPPRPP-------LPPPRPPKPPLP--------PPRPPKPPS-PLGLAQSK 80
           P R +  +PP+PP       L PP    PP+P        PPR P PPS P+ L + +
Sbjct: 543 PRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKR 600



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 48/193 (24%), Positives = 72/193 (37%), Gaps = 37/193 (19%)

Query: 27   PLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPRPP-----KPPSPLGLAQSKV 81
            P P  +PP    PP  L  +   P  P    P   L PP  P      PP+P   + +++
Sbjct: 1808 PAPSSEPPGGEDPP--LDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARI 1865

Query: 82   TLFPSISPS-------SMASLAALASSSLL-----------------KSTKPNPL--EDP 115
             + P+ SPS       S   L +  S S L                 +S +P+PL    P
Sbjct: 1866 KV-PNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP 1924

Query: 116  VSRSVTILARTEPSNDSFNVSSVVSSDRPLTNRVLDGWLLALGDP---LGPCNSSLIALP 172
             SR  +   +T P       +SVV++  P +  +          P   LGP    +  + 
Sbjct: 1925 PSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVS 1984

Query: 173  SISLLLQEFKASL 185
             +S    +F ASL
Sbjct: 1985 GLSAADLDFAASL 1997



 Score = 28.9 bits (63), Expect = 3.5
 Identities = 13/32 (40%), Positives = 16/32 (50%)

Query: 26   PPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRP 57
            PP P R+ PR  + P P P    RP  P  +P
Sbjct: 1100 PPAPRRRTPRENELPLPEPEEQSRPRKPTLQP 1131



 Score = 27.7 bits (60), Expect = 7.9
 Identities = 13/32 (40%), Positives = 15/32 (46%)

Query: 34   PRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPP 65
            P   + P PL    P  PLP   PP+ P  PP
Sbjct: 2343 PAGEESPGPLQERSPLLPLPEDGPPQVPDGPP 2374


>gi|19923345 RNA binding motif protein 12 [Homo sapiens]
          Length = 932

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 33/81 (40%), Positives = 41/81 (50%), Gaps = 16/81 (19%)

Query: 24  PPPPLPP-----RKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSPLGL 76
           PPPP+PP       PP P  PP P+PP  P  P  PP PP PP+P  PP  P PP     
Sbjct: 186 PPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPP----- 240

Query: 77  AQSKVTLFPSISPSSMASLAA 97
               ++  P ++P  +A L A
Sbjct: 241 ----MSGMPPLNPPPVAPLPA 257



 Score = 50.8 bits (120), Expect = 9e-07
 Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 7/94 (7%)

Query: 24  PPPPLPPRKPPRPPKPP-RPLPPNPPRPPLP--PPRPPKPPLPPPRPPKPPSPLGL--AQ 78
           PP P+PP  P  PP PP  P+PP P  PP+   PP    PPL P  PP  P P G+  + 
Sbjct: 206 PPIPVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNP--PPVAPLPAGMNGSG 263

Query: 79  SKVTLFPSISPSSMASLAALASSSLLKSTKPNPL 112
           + + L  +++P  +  L  +    +   +   PL
Sbjct: 264 APMNLNNNLNPMFLGPLNPVNPIQMNSQSSVKPL 297



 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 9/95 (9%)

Query: 24  PPPPLPPRKPPRPPKPP-RPLPPNPPRPPLPPPRPPKPPLPPPRPPKPP------SPLGL 76
           P PP  P  PP PP PP  P+P  PP  PLPP     P  PPP  P P       +P+ L
Sbjct: 209 PVPPPVPTLPPVPPVPPIPPVPSVPPMTPLPPMSGMPPLNPPPVAPLPAGMNGSGAPMNL 268

Query: 77  AQSKVTLFPSISPSSMASLAALASSSLLKSTKPNP 111
             +   +F  + P +  +   + S S +K    NP
Sbjct: 269 NNNLNPMF--LGPLNPVNPIQMNSQSSVKPLPINP 301



 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 31/69 (44%), Positives = 37/69 (53%), Gaps = 9/69 (13%)

Query: 23  SPPPPLPPRKPPRPPKPPRP-LPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSPLGLAQS 79
           SP   +PP  PP PP P  P LPP P  PP+P P    PP+P  PP PP PP P   +  
Sbjct: 180 SPMNTVPP--PPIPPIPAMPSLPPMPSIPPIPVP----PPVPTLPPVPPVPPIPPVPSVP 233

Query: 80  KVTLFPSIS 88
            +T  P +S
Sbjct: 234 PMTPLPPMS 242



 Score = 32.3 bits (72), Expect = 0.32
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 6/77 (7%)

Query: 42  PLPPNPPRPPLPPPRPPKPPLP--PPRPPKPPSPLGLAQSKVTLFPSISP----SSMASL 95
           P   +P     PPP PP P +P  PP P  PP P+      +   P + P     S+  +
Sbjct: 176 PSTASPMNTVPPPPIPPIPAMPSLPPMPSIPPIPVPPPVPTLPPVPPVPPIPPVPSVPPM 235

Query: 96  AALASSSLLKSTKPNPL 112
             L   S +    P P+
Sbjct: 236 TPLPPMSGMPPLNPPPV 252


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,769,368
Number of Sequences: 37866
Number of extensions: 1211362
Number of successful extensions: 78162
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1830
Number of HSP's successfully gapped in prelim test: 966
Number of HSP's that attempted gapping in prelim test: 12873
Number of HSP's gapped (non-prelim): 25353
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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