Guide to the Human Genome
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Search of human proteins with 118343647

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118343647 heat shock protein family B (small), member 11
[Homo sapiens]
         (144 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118343647 heat shock protein family B (small), member 11 [Hom...   291   1e-79
gi|66472382 nischarin [Homo sapiens]                                   31   0.31 
gi|186972143 tripeptidyl peptidase II [Homo sapiens]                   31   0.41 
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...    30   0.70 
gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B ...    29   1.2  
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           29   1.6  
gi|45439327 periplakin [Homo sapiens]                                  28   2.0  
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo...    28   2.7  
gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]    27   4.5  
gi|73747844 ligase III, DNA, ATP-dependent isoform beta precurso...    27   7.7  
gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precurs...    27   7.7  

>gi|118343647 heat shock protein family B (small), member 11 [Homo
           sapiens]
          Length = 144

 Score =  291 bits (745), Expect = 1e-79
 Identities = 144/144 (100%), Positives = 144/144 (100%)

Query: 1   MRKIDLCLSSEGSEVILATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVRIE 60
           MRKIDLCLSSEGSEVILATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVRIE
Sbjct: 1   MRKIDLCLSSEGSEVILATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVRIE 60

Query: 61  RLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQNEEIVAHDGSATYLRFIIV 120
           RLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQNEEIVAHDGSATYLRFIIV
Sbjct: 61  RLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQNEEIVAHDGSATYLRFIIV 120

Query: 121 SAFDHFASVHSVSAEGTVVSNLSS 144
           SAFDHFASVHSVSAEGTVVSNLSS
Sbjct: 121 SAFDHFASVHSVSAEGTVVSNLSS 144


>gi|66472382 nischarin [Homo sapiens]
          Length = 1504

 Score = 31.2 bits (69), Expect = 0.31
 Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 42   TGMFPQEFIICFHKHVRIERLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQ 101
            TG  P + + C  +   +    +Q   V    +E++ S EPVD + + E     T G+++
Sbjct: 1247 TGSTPMQVVTCLTRDSYLTHCFLQHLMVVLSSLERTPSPEPVDKDFYSEFG-NKTTGKME 1305

Query: 102  NEEIV 106
            N E++
Sbjct: 1306 NYELI 1310


>gi|186972143 tripeptidyl peptidase II [Homo sapiens]
          Length = 1249

 Score = 30.8 bits (68), Expect = 0.41
 Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 4/81 (4%)

Query: 5    DLCLSSEGSEVILATSSDEKHPP-ENIIDGNPETFWTT---TGMFPQEFIICFHKHVRIE 60
            D  L ++  +  ++T ++ K    E+ +D   ETFW T   T +F  + +   +KH  + 
Sbjct: 1133 DHLLHTQAQDGAISTDAEGKEEEGESPLDSLAETFWETTKWTDLFDNKVLTFAYKHALVN 1192

Query: 61   RLVIQSYFVQTLKIEKSTSKE 81
            ++  +     T  +E+  +KE
Sbjct: 1193 KMYGRGLKFATKLVEEKPTKE 1213


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
            sapiens]
          Length = 4515

 Score = 30.0 bits (66), Expect = 0.70
 Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 16   ILATSSDEKHPPE---NIIDGNPETFWTTTGMFPQEFIICFHKHVRIERLVIQSYFVQTL 72
            I +TS   KHP +   N  +G P  +W     FPQ F+    +     R +       T 
Sbjct: 4307 IPSTSQKCKHPEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALTFTH 4366

Query: 73   KIEKSTSKEPVDFEQWIEKDL 93
             +  +T+ +   F  ++ K L
Sbjct: 4367 HVISNTTDKDEKFSVFMPKKL 4387


>gi|11034845 Regulation of nuclear pre-mRNA domain containing 1B
           [Homo sapiens]
          Length = 326

 Score = 29.3 bits (64), Expect = 1.2
 Identities = 19/52 (36%), Positives = 24/52 (46%)

Query: 60  ERLVIQSYFVQTLKIEKSTSKEPVDFEQWIEKDLVHTEGQLQNEEIVAHDGS 111
           ER V    F+Q LK+    SK P       +K L  T  Q+Q EE   + GS
Sbjct: 113 ERSVYGGEFIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGS 164


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 28.9 bits (63), Expect = 1.6
 Identities = 12/31 (38%), Positives = 22/31 (70%), Gaps = 3/31 (9%)

Query: 54   HKHVRIERLVIQSYFVQTLKIEKSTSKEPVD 84
            H  + +ERL++QSY    L+ +K+T+ +P+D
Sbjct: 1549 HLQMEVERLIVQSY---VLEHQKTTTPDPMD 1576


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 22/99 (22%), Positives = 40/99 (40%), Gaps = 4/99 (4%)

Query: 17  LATSSDEKHPPENIIDGNPETFWTTTGMFPQEFIICFHKHVRIERLVIQSYFVQTLKIEK 76
           L   ++ +   EN +    E  WT     PQE ++      ++   V++  F Q     +
Sbjct: 899 LDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQL----Q 954

Query: 77  STSKEPVDFEQWIEKDLVHTEGQLQNEEIVAHDGSATYL 115
            T  E     Q ++++L   + QL+  E    DG   Y+
Sbjct: 955 RTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYV 993


>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
            sapiens]
          Length = 2517

 Score = 28.1 bits (61), Expect = 2.7
 Identities = 12/45 (26%), Positives = 22/45 (48%), Gaps = 1/45 (2%)

Query: 21   SDEKHPPENIIDGNPETFWTTTGMFPQEFI-ICFHKHVRIERLVI 64
            S   H    + D NP+T+W + G     +I +  H+ V + +L +
Sbjct: 1176 SSNPHRASKLTDHNPKTYWESNGSTGSHYITLHMHRGVLVRQLTL 1220


>gi|7705855 hydroxysteroid (17-beta) dehydrogenase 12 [Homo sapiens]
          Length = 312

 Score = 27.3 bits (59), Expect = 4.5
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 5/51 (9%)

Query: 37  TFWTTTGMFPQEFIICFHKHVRIERLVIQS---YFVQT--LKIEKSTSKEP 82
           T ++ T  F   F  C H+  R + + +QS   YFV T   KI K T  +P
Sbjct: 200 TIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKP 250


>gi|73747844 ligase III, DNA, ATP-dependent isoform beta precursor
           [Homo sapiens]
          Length = 949

 Score = 26.6 bits (57), Expect = 7.7
 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 15/72 (20%)

Query: 62  LVIQSYFVQTLK---------IEKSTSKEPVDFEQWIEKDLVHTEGQ-LQNEEIVAHDGS 111
           L  + +F QTL+           K   ++   F QW E DL+H     L+ + +++  GS
Sbjct: 3   LAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQGS 62

Query: 112 -----ATYLRFI 118
                ATYL F+
Sbjct: 63  HLRSRATYLVFL 74


>gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precursor
           [Homo sapiens]
          Length = 1009

 Score = 26.6 bits (57), Expect = 7.7
 Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 15/72 (20%)

Query: 62  LVIQSYFVQTLK---------IEKSTSKEPVDFEQWIEKDLVHTEGQ-LQNEEIVAHDGS 111
           L  + +F QTL+           K   ++   F QW E DL+H     L+ + +++  GS
Sbjct: 3   LAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQGS 62

Query: 112 -----ATYLRFI 118
                ATYL F+
Sbjct: 63  HLRSRATYLVFL 74


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,333,696
Number of Sequences: 37866
Number of extensions: 203793
Number of successful extensions: 443
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 440
Number of HSP's gapped (non-prelim): 11
length of query: 144
length of database: 18,247,518
effective HSP length: 92
effective length of query: 52
effective length of database: 14,763,846
effective search space: 767719992
effective search space used: 767719992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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