Search of human proteins with 117938756

Search of human proteins with 117938756

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938756 constitutive androstane receptor isoform 1 [Homo
sapiens]
         (357 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   721   0.0  
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   704   0.0  
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   691   0.0  
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   631   0.0  
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   627   e-180
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   624   e-179
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   616   e-177
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   614   e-176
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   604   e-173
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   563   e-161
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   550   e-157
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   533   e-152
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   527   e-150
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   523   e-148
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   446   e-125
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   291   6e-79
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   280   2e-75
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   280   2e-75
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   176   2e-44
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   176   2e-44
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            161   1e-39
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            161   1e-39
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             161   1e-39
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo...   154   9e-38
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   154   1e-37
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...   148   8e-36
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   147   1e-35
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    147   1e-35
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     147   1e-35
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   147   1e-35

>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  721 bits (1861), Expect = 0.0
 Identities = 357/357 (100%), Positives = 357/357 (100%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300

Query: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
           LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  704 bits (1818), Expect = 0.0
 Identities = 352/357 (98%), Positives = 352/357 (98%), Gaps = 5/357 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295

Query: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
           LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 296 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  691 bits (1783), Expect = 0.0
 Identities = 348/357 (97%), Positives = 348/357 (97%), Gaps = 9/357 (2%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 291

Query: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
           LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 292 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  631 bits (1627), Expect = 0.0
 Identities = 318/322 (98%), Positives = 318/322 (98%), Gaps = 4/322 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 335
           PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 302

Query: 336 GYQIQHIQGLSAMMPLLQEICS 357
           GYQIQHIQGLSAMMPLLQEICS
Sbjct: 303 GYQIQHIQGLSAMMPLLQEICS 324


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  627 bits (1616), Expect = e-180
 Identities = 311/315 (98%), Positives = 311/315 (98%), Gaps = 4/315 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT
Sbjct: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 296

Query: 301 LQSYIKGQQRRPRDR 315
           LQSYIKGQQRRPRDR
Sbjct: 297 LQSYIKGQQRRPRDR 311


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  624 bits (1608), Expect = e-179
 Identities = 310/315 (98%), Positives = 310/315 (98%), Gaps = 5/315 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295

Query: 301 LQSYIKGQQRRPRDR 315
           LQSYIKGQQRRPRDR
Sbjct: 296 LQSYIKGQQRRPRDR 310


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  616 bits (1589), Expect = e-177
 Identities = 314/357 (87%), Positives = 314/357 (87%), Gaps = 43/357 (12%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
                                             APYLTDRPGVTQRDEIDQLQEEMALT
Sbjct: 232 ----------------------------------APYLTDRPGVTQRDEIDQLQEEMALT 257

Query: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
           LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 258 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  614 bits (1584), Expect = e-176
 Identities = 313/322 (97%), Positives = 313/322 (97%), Gaps = 9/322 (2%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 241

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 335
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 242 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 297

Query: 336 GYQIQHIQGLSAMMPLLQEICS 357
           GYQIQHIQGLSAMMPLLQEICS
Sbjct: 298 GYQIQHIQGLSAMMPLLQEICS 319


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  604 bits (1557), Expect = e-173
 Identities = 309/357 (86%), Positives = 309/357 (86%), Gaps = 48/357 (13%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
                                                  DRPGVTQRDEIDQLQEEMALT
Sbjct: 232 ---------------------------------------DRPGVTQRDEIDQLQEEMALT 252

Query: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
           LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 253 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 309


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  563 bits (1452), Expect = e-161
 Identities = 280/280 (100%), Positives = 280/280 (100%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA
Sbjct: 187 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 246

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 315
           PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  550 bits (1417), Expect = e-157
 Identities = 276/280 (98%), Positives = 276/280 (98%), Gaps = 4/280 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 315
           PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  533 bits (1374), Expect = e-152
 Identities = 271/280 (96%), Positives = 271/280 (96%), Gaps = 9/280 (3%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 241

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 315
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 242 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  527 bits (1358), Expect = e-150
 Identities = 274/322 (85%), Positives = 274/322 (85%), Gaps = 48/322 (14%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGAR                                            
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 335
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 203 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 258

Query: 336 GYQIQHIQGLSAMMPLLQEICS 357
           GYQIQHIQGLSAMMPLLQEICS
Sbjct: 259 GYQIQHIQGLSAMMPLLQEICS 280


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  523 bits (1347), Expect = e-148
 Identities = 267/315 (84%), Positives = 267/315 (84%), Gaps = 48/315 (15%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
                                                  DRPGVTQRDEIDQLQEEMALT
Sbjct: 232 ---------------------------------------DRPGVTQRDEIDQLQEEMALT 252

Query: 301 LQSYIKGQQRRPRDR 315
           LQSYIKGQQRRPRDR
Sbjct: 253 LQSYIKGQQRRPRDR 267


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  446 bits (1148), Expect = e-125
 Identities = 232/280 (82%), Positives = 232/280 (82%), Gaps = 48/280 (17%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275
           NFLCGPLRYTIEDGAR                                            
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202

Query: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 315
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 203 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  291 bits (745), Expect = 6e-79
 Identities = 161/361 (44%), Positives = 223/361 (61%), Gaps = 26/361 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQPLPTLAP--------VLPLVTHFADINTFMVLQVIKF 175
              T F  F  FR    L      +    P        +  L+ H AD++T+M   +I F
Sbjct: 161 TFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISF 220

Query: 176 TKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPT 235
            K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L Y +ED A     
Sbjct: 221 AKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG---- 276

Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQE 295
            GFQ   LE +  FH  L+KLQL E EYVL+ A++LFSP     DRPGV Q   +DQLQE
Sbjct: 277 -GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSP-----DRPGVLQHRVVDQLQE 330

Query: 296 EMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLLQE 354
           + A+TL+SYI+  + +P  RFL+ K++ +L ELRSIN  +  ++  IQ +     PL+QE
Sbjct: 331 QFAITLKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQE 390

Query: 355 I 355
           +
Sbjct: 391 L 391


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  280 bits (715), Expect = 2e-75
 Identities = 164/398 (41%), Positives = 226/398 (56%), Gaps = 63/398 (15%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 80  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 139

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 140 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 199

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 200 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 259

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 260 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 319

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQL 258
            E+C +  NT F  +T  + CG L Y +ED A      GFQ   LE +  FH  L+KLQL
Sbjct: 320 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-----GFQQLLLEPMLKFHYMLKKLQL 374

Query: 259 QEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY 318
            E EYVL+ A++LFSP     DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  RFL+
Sbjct: 375 HEEEYVLMQAISLFSP-----DRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF 429

Query: 319 AKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 355
            K++ +L ELRSIN  +  ++  IQ +     PL+QE+
Sbjct: 430 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 467


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  280 bits (715), Expect = 2e-75
 Identities = 164/398 (41%), Positives = 226/398 (56%), Gaps = 63/398 (15%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 161 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 220

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 221 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 280

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQL 258
            E+C +  NT F  +T  + CG L Y +ED A      GFQ   LE +  FH  L+KLQL
Sbjct: 281 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-----GFQQLLLEPMLKFHYMLKKLQL 335

Query: 259 QEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY 318
            E EYVL+ A++LFSP     DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  RFL+
Sbjct: 336 HEEEYVLMQAISLFSP-----DRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLF 390

Query: 319 AKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 355
            K++ +L ELRSIN  +  ++  IQ +     PL+QE+
Sbjct: 391 LKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 428


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  176 bits (447), Expect = 2e-44
 Identities = 116/361 (32%), Positives = 182/361 (50%), Gaps = 32/361 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 53  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 112

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 113 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 172

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 173 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 227

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVSPT 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+    
Sbjct: 228 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAK---- 283

Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQE 295
            G QVEF+  +F F   + +LQL + E+ LL A+++FS      DRP V  + ++++LQ 
Sbjct: 284 AGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFS-----ADRPNVQDQLQVERLQH 338

Query: 296 EMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQE 354
                L +Y+      P DR ++ ++L  L  LR+++  +  Q+  ++     + PLL E
Sbjct: 339 TYVEALHAYV--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSE 396

Query: 355 I 355
           I
Sbjct: 397 I 397


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  176 bits (447), Expect = 2e-44
 Identities = 116/361 (32%), Positives = 182/361 (50%), Gaps = 32/361 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 98  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 157

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 158 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 217

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 218 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 272

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVSPT 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+    
Sbjct: 273 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAK---- 328

Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQE 295
            G QVEF+  +F F   + +LQL + E+ LL A+++FS      DRP V  + ++++LQ 
Sbjct: 329 AGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFS-----ADRPNVQDQLQVERLQH 383

Query: 296 EMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQE 354
                L +Y+      P DR ++ ++L  L  LR+++  +  Q+  ++     + PLL E
Sbjct: 384 TYVEALHAYV--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSE 441

Query: 355 I 355
           I
Sbjct: 442 I 442


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  161 bits (407), Expect = 1e-39
 Identities = 116/359 (32%), Positives = 175/359 (48%), Gaps = 38/359 (10%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGV 284
           T     R     G      + +F    +L    L + E  LL A+ L S     +DRPG+
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMS-----SDRPGL 386

Query: 285 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 343
              + I++ Q+   L  + YI    R+      + KLL  + +LR I   +  +  H++
Sbjct: 387 ACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  161 bits (407), Expect = 1e-39
 Identities = 116/359 (32%), Positives = 175/359 (48%), Gaps = 38/359 (10%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGV 284
           T     R     G      + +F    +L    L + E  LL A+ L S     +DRPG+
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMS-----SDRPGL 386

Query: 285 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 343
              + I++ Q+   L  + YI    R+      + KLL  + +LR I   +  +  H++
Sbjct: 387 ACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  161 bits (407), Expect = 1e-39
 Identities = 116/359 (32%), Positives = 175/359 (48%), Gaps = 38/359 (10%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGV 284
           T     R     G      + +F    +L    L + E  LL A+ L S     +DRPG+
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMS-----SDRPGL 386

Query: 285 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 343
              + I++ Q+   L  + YI    R+      + KLL  + +LR I   +  +  H++
Sbjct: 387 ACVERIEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443


>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
           sapiens]
          Length = 472

 Score =  154 bits (390), Expect = 9e-38
 Identities = 110/340 (32%), Positives = 174/340 (51%), Gaps = 32/340 (9%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPA 65
           DEL  CVVCGD+A+GYH+NALTCEGCKGFFRR+++K+    C   G+C +    RR C  
Sbjct: 124 DEL--CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQE 181

Query: 66  CRLQKCLDAGMRKDMILS-AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRH 124
           CRL+KC + GM  + +L+  +  + R  K  ++ A QT   ++++ E      + + T+ 
Sbjct: 182 CRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQT---VNEDSEGRDLRQVTSTTKS 238

Query: 125 MGTMFEQFVQFRPPAHLFI---HHQPLPTLAPVLPLVTHFADINTFMVLQ---------V 172
                E     +   H  +   + Q +P       L   F+    F++L          +
Sbjct: 239 CREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVL 298

Query: 173 IKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARV 232
           ++FTK LP F++L  EDQI+LLKG+AVE   +     F  +  +     L   I +    
Sbjct: 299 VEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNS--- 355

Query: 233 SPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQ 292
               G   E++  +F F+ ++ +L++ + EY LL A+ + SP     DR  +  R+ +++
Sbjct: 356 ----GISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSP-----DRQYIKDREAVEK 406

Query: 293 LQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 332
           LQE +   LQ   K  Q  P +   +A LLG L ELR+ N
Sbjct: 407 LQEPLLDVLQKLCKIHQ--PENPQHFACLLGRLTELRTFN 444


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  154 bits (389), Expect = 1e-37
 Identities = 113/360 (31%), Positives = 172/360 (47%), Gaps = 40/360 (11%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPL---R 223
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +   R
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 224 YTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPG 283
             +++G       G  V   + +F    +L    L + E  LL A+ L S     TDR G
Sbjct: 285 EQLKNG-------GLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMS-----TDRSG 331

Query: 284 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 343
           +   D+I++ QE   L  + Y+    R+      + KLL  + +LR I   +  +  H++
Sbjct: 332 LLCVDKIEKSQEAYLLAFEHYV--NHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMK 389


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score =  148 bits (373), Expect = 8e-36
 Identities = 111/347 (31%), Positives = 166/347 (47%), Gaps = 40/347 (11%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPL---R 223
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +   R
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 224 YTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPG 283
             +++G       G  V   + +F    +L    L + E  LL A+ L S     TDR G
Sbjct: 285 EQLKNG-------GLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMS-----TDRSG 331

Query: 284 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRS 330
           +   D+I++ QE   L  + Y+    R+      + KLL    E++S
Sbjct: 332 LLCVDKIEKSQEAYLLAFEHYV--NHRKHNIPHFWPKLLMKEREVQS 376


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  147 bits (372), Expect = 1e-35
 Identities = 103/352 (29%), Positives = 173/352 (49%), Gaps = 33/352 (9%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 88  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 310

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKG 307
            F   L  L++ + E  LL+A+ L        DR  + Q D +D LQE +   L+ Y++ 
Sbjct: 311 AFANQLLPLEMDDAETGLLSAICLI-----CGDRQDLEQPDRVDMLQEPLLEALKVYVR- 364

Query: 308 QQRRPRDRFLYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 355
            +RRP    ++ K+L  + +LRSI+     ++      I G  +M PL+QE+
Sbjct: 365 -KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  147 bits (372), Expect = 1e-35
 Identities = 103/352 (29%), Positives = 173/352 (49%), Gaps = 33/352 (9%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 83  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 143 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 192

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 193 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 252

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 253 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 305

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKG 307
            F   L  L++ + E  LL+A+ L        DR  + Q D +D LQE +   L+ Y++ 
Sbjct: 306 AFANQLLPLEMDDAETGLLSAICLI-----CGDRQDLEQPDRVDMLQEPLLEALKVYVR- 359

Query: 308 QQRRPRDRFLYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 355
            +RRP    ++ K+L  + +LRSI+     ++      I G  +M PL+QE+
Sbjct: 360 -KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 408


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  147 bits (372), Expect = 1e-35
 Identities = 103/352 (29%), Positives = 173/352 (49%), Gaps = 33/352 (9%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 88  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 310

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKG 307
            F   L  L++ + E  LL+A+ L        DR  + Q D +D LQE +   L+ Y++ 
Sbjct: 311 AFANQLLPLEMDDAETGLLSAICLI-----CGDRQDLEQPDRVDMLQEPLLEALKVYVR- 364

Query: 308 QQRRPRDRFLYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 355
            +RRP    ++ K+L  + +LRSI+     ++      I G  +M PL+QE+
Sbjct: 365 -KRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  147 bits (372), Expect = 1e-35
 Identities = 95/325 (29%), Positives = 163/325 (50%), Gaps = 27/325 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+   +CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 79  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 138

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+ +        +LS + EELI  +  AH        E
Sbjct: 139 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 188

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           +      +   L L   F+++ T  ++++++F K LP F  L I DQ
Sbjct: 189 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 248

Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
           I+LLK A ++I  + + T +  +           T  DG  ++ T      F    +L+F
Sbjct: 249 ITLLKAACLDILMLRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 301

Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKG 307
            F G L  L++ + E  LL+A+ L        DR  + + +++D+LQE +   L+ Y   
Sbjct: 302 AFAGQLLPLEMDDTETGLLSAICLI-----CGDRMDLEEPEKVDKLQEPLLEALRLY--A 354

Query: 308 QQRRPRDRFLYAKLLGLLAELRSIN 332
           ++RRP   +++ ++L  + +LR I+
Sbjct: 355 RRRRPSQPYMFPRMLMKITDLRGIS 379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,151,359
Number of Sequences: 37866
Number of extensions: 570300
Number of successful extensions: 2358
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2008
Number of HSP's gapped (non-prelim): 204
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.