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Search of human proteins with 117938754
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938754 constitutive androstane receptor isoform 4 [Homo
sapiens]
(314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa... 637 0.0
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa... 620 e-178
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa... 616 e-177
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi... 610 e-175
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa... 608 e-174
gi|117938732 constitutive androstane receptor isoform 11 [Homo s... 544 e-155
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa... 541 e-154
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa... 540 e-154
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa... 537 e-153
gi|117938750 constitutive androstane receptor isoform 10 [Homo s... 533 e-152
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa... 527 e-150
gi|117938742 constitutive androstane receptor isoform 15 [Homo s... 463 e-130
gi|117938744 constitutive androstane receptor isoform 13 [Homo s... 460 e-130
gi|117938738 constitutive androstane receptor isoform 12 [Homo s... 459 e-129
gi|117938748 constitutive androstane receptor isoform 14 [Homo s... 452 e-127
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof... 245 3e-65
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof... 234 1e-61
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof... 234 1e-61
gi|189491771 thyroid hormone receptor, beta [Homo sapiens] 145 5e-35
gi|189491769 thyroid hormone receptor, beta [Homo sapiens] 145 5e-35
gi|40806162 thyroid hormone receptor, beta [Homo sapiens] 145 5e-35
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso... 139 3e-33
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 139 3e-33
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ... 139 3e-33
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s... 139 3e-33
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi... 139 3e-33
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi... 134 8e-32
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 129 3e-30
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 129 3e-30
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 129 3e-30
>gi|117938754 constitutive androstane receptor isoform 4 [Homo
sapiens]
Length = 314
Score = 637 bits (1643), Expect = 0.0
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARAPYLTDRPG 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARAPYLTDRPG
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARAPYLTDRPG 240
Query: 241 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ
Sbjct: 241 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
Query: 301 GLSAMMPLLQEICS 314
GLSAMMPLLQEICS
Sbjct: 301 GLSAMMPLLQEICS 314
>gi|117938734 constitutive androstane receptor isoform 5 [Homo
sapiens]
Length = 309
Score = 620 bits (1600), Expect = e-178
Identities = 309/314 (98%), Positives = 309/314 (98%), Gaps = 5/314 (1%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARAPYLTDRPG 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR DRPG
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR-----DRPG 235
Query: 241 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ
Sbjct: 236 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 295
Query: 301 GLSAMMPLLQEICS 314
GLSAMMPLLQEICS
Sbjct: 296 GLSAMMPLLQEICS 309
>gi|117938756 constitutive androstane receptor isoform 1 [Homo
sapiens]
Length = 357
Score = 616 bits (1589), Expect = e-177
Identities = 314/357 (87%), Positives = 314/357 (87%), Gaps = 43/357 (12%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
Query: 232 ----------------------------------APYLTDRPGVTQRDEIDQLQEEMALT 257
APYLTDRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
Query: 258 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314
LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
>gi|4826661 constitutive androstane receptor isoform 3 [Homo
sapiens]
Length = 348
Score = 610 bits (1572), Expect = e-175
Identities = 310/348 (89%), Positives = 311/348 (89%), Gaps = 34/348 (9%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
Query: 232 -------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 266
A + DRPGVTQRDEIDQLQEEMALTLQSYIKGQQ
Sbjct: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 300
Query: 267 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314
RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
>gi|117938752 constitutive androstane receptor isoform 2 [Homo
sapiens]
Length = 352
Score = 608 bits (1568), Expect = e-174
Identities = 310/352 (88%), Positives = 311/352 (88%), Gaps = 38/352 (10%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
Query: 232 -----------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYI 262
A + DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
Query: 263 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
>gi|117938732 constitutive androstane receptor isoform 11 [Homo
sapiens]
Length = 280
Score = 544 bits (1401), Expect = e-155
Identities = 274/279 (98%), Positives = 274/279 (98%), Gaps = 5/279 (1%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY 275
NFLCGPLRYTIEDGAR DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY
Sbjct: 187 NFLCGPLRYTIEDGAR-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLY 241
Query: 276 AKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314
AKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 242 AKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 280
>gi|117938736 constitutive androstane receptor isoform 9 [Homo
sapiens]
Length = 324
Score = 541 bits (1394), Expect = e-154
Identities = 279/318 (87%), Positives = 279/318 (87%), Gaps = 39/318 (12%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGAR---------------------------------------APYLT 236
NFLCGPLRYTIEDGAR APYLT
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
Query: 237 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 296
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI
Sbjct: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 306
Query: 297 QHIQGLSAMMPLLQEICS 314
QHIQGLSAMMPLLQEICS
Sbjct: 307 QHIQGLSAMMPLLQEICS 324
>gi|117938740 constitutive androstane receptor isoform 8 [Homo
sapiens]
Length = 296
Score = 540 bits (1390), Expect = e-154
Identities = 267/272 (98%), Positives = 267/272 (98%), Gaps = 5/272 (1%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARAPYLTDRPG 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR DRPG
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR-----DRPG 235
Query: 241 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272
VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 236 VTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 267
>gi|117938729 constitutive androstane receptor isoform 6 [Homo
sapiens]
Length = 340
Score = 537 bits (1383), Expect = e-153
Identities = 272/311 (87%), Positives = 272/311 (87%), Gaps = 39/311 (12%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
Query: 232 ------------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSY 261
APYLTDRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300
Query: 262 IKGQQRRPRDR 272
IKGQQRRPRDR
Sbjct: 301 IKGQQRRPRDR 311
>gi|117938750 constitutive androstane receptor isoform 10 [Homo
sapiens]
Length = 319
Score = 533 bits (1373), Expect = e-152
Identities = 275/313 (87%), Positives = 276/313 (88%), Gaps = 34/313 (10%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGAR----------------------------------APYLTDRPGV 241
NFLCGPLRYTIEDGAR A + DRPGV
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
Query: 242 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 301
TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 306
Query: 302 LSAMMPLLQEICS 314
LSAMMPLLQEICS
Sbjct: 307 LSAMMPLLQEICS 319
>gi|117938746 constitutive androstane receptor isoform 7 [Homo
sapiens]
Length = 339
Score = 527 bits (1358), Expect = e-150
Identities = 268/310 (86%), Positives = 269/310 (86%), Gaps = 38/310 (12%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
Query: 232 -----------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYI 262
A + DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
Query: 263 KGQQRRPRDR 272
KGQQRRPRDR
Sbjct: 301 KGQQRRPRDR 310
>gi|117938742 constitutive androstane receptor isoform 15 [Homo
sapiens]
Length = 267
Score = 463 bits (1191), Expect = e-130
Identities = 232/237 (97%), Positives = 232/237 (97%), Gaps = 5/237 (2%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272
NFLCGPLRYTIEDGAR DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 187 NFLCGPLRYTIEDGAR-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
>gi|117938744 constitutive androstane receptor isoform 13 [Homo
sapiens]
Length = 311
Score = 460 bits (1184), Expect = e-130
Identities = 237/276 (85%), Positives = 237/276 (85%), Gaps = 39/276 (14%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGAR---------------------------------------APYLT 236
NFLCGPLRYTIEDGAR APYLT
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246
Query: 237 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
>gi|117938738 constitutive androstane receptor isoform 12 [Homo
sapiens]
Length = 315
Score = 459 bits (1180), Expect = e-129
Identities = 237/280 (84%), Positives = 237/280 (84%), Gaps = 43/280 (15%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGAR-------------------------------------------A 232
NFLCGPLRYTIEDGAR A
Sbjct: 187 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 246
Query: 233 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272
PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286
>gi|117938748 constitutive androstane receptor isoform 14 [Homo
sapiens]
Length = 306
Score = 452 bits (1163), Expect = e-127
Identities = 233/271 (85%), Positives = 234/271 (86%), Gaps = 34/271 (12%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGAR----------------------------------APYLTDRPGV 241
NFLCGPLRYTIEDGAR A + DRPGV
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246
Query: 242 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272
TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
3 [Homo sapiens]
Length = 397
Score = 245 bits (626), Expect = 3e-65
Identities = 139/351 (39%), Positives = 198/351 (56%), Gaps = 49/351 (13%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
C VCGD+ATGYHFN +TCEGCKGFFRR + ++ CPF G+CE+++ RR C ACRL+
Sbjct: 41 CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100
Query: 70 KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
KCL++GM+K+MI+S EA+ RRA ++++++T Q L++EQ +IR L+ A +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160
Query: 124 HMGTMFEQFVQFRPPAHLFIHHQPLPTLAP--------VLPLVTHFADINTFMVLQVIKF 175
T F F FR L + P + L+ H AD++T+M +I F
Sbjct: 161 TFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISF 220
Query: 176 TKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR---- 231
K + FR LPIEDQISLLKGAA E+C + NT F +T + CG L Y +ED A
Sbjct: 221 AKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQ 280
Query: 232 -----------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYI 262
+ + DRPGV Q +DQLQE+ A+TL+SYI
Sbjct: 281 LLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYI 340
Query: 263 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 312
+ + +P RFL+ K++ +L ELRSIN + ++ IQ + PL+QE+
Sbjct: 341 ECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 391
>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
2 [Homo sapiens]
Length = 473
Score = 234 bits (596), Expect = 1e-61
Identities = 142/388 (36%), Positives = 201/388 (51%), Gaps = 86/388 (22%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPF-AGSCEVSKTQRRHCPACRLQ 69
C VCGD+ATGYHFN +TCEGCKGFFRR + ++ CPF G+CE+++ RR C ACRL+
Sbjct: 80 CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 139
Query: 70 KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
KCL++GM+K+MI+S EA+ RRA ++++++T Q L++EQ +IR L+ A +
Sbjct: 140 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 199
Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
T F F FR P L + P AP
Sbjct: 200 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 259
Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
+ L+ H AD++T+M +I F K + FR LPIEDQISLLKGAA
Sbjct: 260 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 319
Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------------------------- 231
E+C + NT F +T + CG L Y +ED A
Sbjct: 320 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEY 379
Query: 232 ------APYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAEL 285
+ + DRPGV Q +DQLQE+ A+TL+SYI+ + +P RFL+ K++ +L EL
Sbjct: 380 VLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTEL 439
Query: 286 RSINEAYGYQIQHIQGLSAM-MPLLQEI 312
RSIN + ++ IQ + PL+QE+
Sbjct: 440 RSINAQHTQRLLRIQDIHPFATPLMQEL 467
>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
1 [Homo sapiens]
Length = 434
Score = 234 bits (596), Expect = 1e-61
Identities = 142/388 (36%), Positives = 201/388 (51%), Gaps = 86/388 (22%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPF-AGSCEVSKTQRRHCPACRLQ 69
C VCGD+ATGYHFN +TCEGCKGFFRR + ++ CPF G+CE+++ RR C ACRL+
Sbjct: 41 CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100
Query: 70 KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
KCL++GM+K+MI+S EA+ RRA ++++++T Q L++EQ +IR L+ A +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160
Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
T F F FR P L + P AP
Sbjct: 161 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 220
Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
+ L+ H AD++T+M +I F K + FR LPIEDQISLLKGAA
Sbjct: 221 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 280
Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------------------------- 231
E+C + NT F +T + CG L Y +ED A
Sbjct: 281 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEY 340
Query: 232 ------APYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAEL 285
+ + DRPGV Q +DQLQE+ A+TL+SYI+ + +P RFL+ K++ +L EL
Sbjct: 341 VLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTEL 400
Query: 286 RSINEAYGYQIQHIQGLSAM-MPLLQEI 312
RSIN + ++ IQ + PL+QE+
Sbjct: 401 RSINAQHTQRLLRIQDIHPFATPLMQEL 428
>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 145 bits (366), Expect = 5e-35
Identities = 110/349 (31%), Positives = 162/349 (46%), Gaps = 61/349 (17%)
Query: 5 EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
+DEL CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ P +C + G C + K R
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160
Query: 63 CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
C CR +KC+ GM D++L +R + R ++ +L K E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220
Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
LI+T+ AH T G+ ++Q +F P I P+ AP L +HF I
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276
Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICH-------------IVLNTTFCL 212
T + +V+ F K LP+F LP EDQI LLKG +EI + LN +
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336
Query: 213 ---QTQNFLCGPLRYTIED------------------GARAPYLTDRPGVTQRDEIDQLQ 251
Q +N G + I D A +DRPG+ + I++ Q
Sbjct: 337 TRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQ 396
Query: 252 EEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
+ L + YI R+ + KLL + +LR I + + H++
Sbjct: 397 DSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443
>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 145 bits (366), Expect = 5e-35
Identities = 110/349 (31%), Positives = 162/349 (46%), Gaps = 61/349 (17%)
Query: 5 EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
+DEL CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ P +C + G C + K R
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160
Query: 63 CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
C CR +KC+ GM D++L +R + R ++ +L K E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220
Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
LI+T+ AH T G+ ++Q +F P I P+ AP L +HF I
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276
Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICH-------------IVLNTTFCL 212
T + +V+ F K LP+F LP EDQI LLKG +EI + LN +
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336
Query: 213 ---QTQNFLCGPLRYTIED------------------GARAPYLTDRPGVTQRDEIDQLQ 251
Q +N G + I D A +DRPG+ + I++ Q
Sbjct: 337 TRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQ 396
Query: 252 EEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
+ L + YI R+ + KLL + +LR I + + H++
Sbjct: 397 DSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443
>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 145 bits (366), Expect = 5e-35
Identities = 110/349 (31%), Positives = 162/349 (46%), Gaps = 61/349 (17%)
Query: 5 EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
+DEL CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ P +C + G C + K R
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160
Query: 63 CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
C CR +KC+ GM D++L +R + R ++ +L K E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220
Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
LI+T+ AH T G+ ++Q +F P I P+ AP L +HF I
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276
Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICH-------------IVLNTTFCL 212
T + +V+ F K LP+F LP EDQI LLKG +EI + LN +
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336
Query: 213 ---QTQNFLCGPLRYTIED------------------GARAPYLTDRPGVTQRDEIDQLQ 251
Q +N G + I D A +DRPG+ + I++ Q
Sbjct: 337 TRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQ 396
Query: 252 EEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
+ L + YI R+ + KLL + +LR I + + H++
Sbjct: 397 DSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443
>gi|194294519 nuclear receptor subfamily 1, group H, member 3
isoform c [Homo sapiens]
Length = 402
Score = 139 bits (350), Expect = 3e-33
Identities = 101/352 (28%), Positives = 159/352 (45%), Gaps = 57/352 (16%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VCGD+A+G+H+N L+CEGCKGFFRR+V K C G C + RR C CRL+K
Sbjct: 53 CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 112
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
C AGMR++ +LS E + L++ K+ + RA P QLS EQ +I L
Sbjct: 113 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 172
Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
+ A + F ++ P P H + HF ++ V +++ F
Sbjct: 173 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 227
Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARAP-- 233
K LP F L EDQI+LLK +A+E+ + + + +++ Y ED A+A
Sbjct: 228 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQ 287
Query: 234 --------------------------------YLTDRPGVTQRDEIDQLQEEMALTLQSY 261
+ DRP V + ++++LQ L +Y
Sbjct: 288 VEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAY 347
Query: 262 IKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 312
+ P DR ++ ++L L LR+++ + Q+ ++ + PLL EI
Sbjct: 348 V--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 397
>gi|194294517 nuclear receptor subfamily 1, group H, member 3
isoform a [Homo sapiens]
Length = 447
Score = 139 bits (350), Expect = 3e-33
Identities = 101/352 (28%), Positives = 159/352 (45%), Gaps = 57/352 (16%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VCGD+A+G+H+N L+CEGCKGFFRR+V K C G C + RR C CRL+K
Sbjct: 98 CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 157
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
C AGMR++ +LS E + L++ K+ + RA P QLS EQ +I L
Sbjct: 158 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 217
Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
+ A + F ++ P P H + HF ++ V +++ F
Sbjct: 218 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 272
Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARAP-- 233
K LP F L EDQI+LLK +A+E+ + + + +++ Y ED A+A
Sbjct: 273 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQ 332
Query: 234 --------------------------------YLTDRPGVTQRDEIDQLQEEMALTLQSY 261
+ DRP V + ++++LQ L +Y
Sbjct: 333 VEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAY 392
Query: 262 IKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 312
+ P DR ++ ++L L LR+++ + Q+ ++ + PLL EI
Sbjct: 393 V--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 442
>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
sapiens]
Length = 427
Score = 139 bits (350), Expect = 3e-33
Identities = 64/138 (46%), Positives = 90/138 (65%), Gaps = 5/138 (3%)
Query: 9 RNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRL 68
R C VCGD+ATG+HFNA+TCEGCKGFFRR++ + TCPF G C ++K RRHC ACRL
Sbjct: 22 RICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRL 81
Query: 69 QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----PVQLSKEQEELIRTLLGAHTR 123
++C+D GM K+ IL+ E + +R +R+ ++ +LS+EQ+ +I LL AH +
Sbjct: 82 KRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHK 141
Query: 124 HMGTMFEQFVQFRPPAHL 141
+ F QFRPP +
Sbjct: 142 TYDPTYSDFCQFRPPVRV 159
Score = 84.3 bits (207), Expect = 1e-16
Identities = 53/177 (29%), Positives = 86/177 (48%), Gaps = 36/177 (20%)
Query: 155 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 214
L ++ H AD+ ++ + +VI F K +P FR L EDQI LLK +A+E+ + N +F +
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283
Query: 215 QNFLCG--PLRYTIEDGARAPY----------------------------------LTDR 238
++ CG +Y + D +A + DR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343
Query: 239 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 295
PGV I+ +Q+ ++ TLQ+YI+ + P LYAK++ LA+LRS+NE + Q
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQ 400
>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
sapiens]
Length = 427
Score = 139 bits (350), Expect = 3e-33
Identities = 64/138 (46%), Positives = 90/138 (65%), Gaps = 5/138 (3%)
Query: 9 RNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRL 68
R C VCGD+ATG+HFNA+TCEGCKGFFRR++ + TCPF G C ++K RRHC ACRL
Sbjct: 22 RICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRL 81
Query: 69 QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----PVQLSKEQEELIRTLLGAHTR 123
++C+D GM K+ IL+ E + +R +R+ ++ +LS+EQ+ +I LL AH +
Sbjct: 82 KRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHK 141
Query: 124 HMGTMFEQFVQFRPPAHL 141
+ F QFRPP +
Sbjct: 142 TYDPTYSDFCQFRPPVRV 159
Score = 84.3 bits (207), Expect = 1e-16
Identities = 53/177 (29%), Positives = 86/177 (48%), Gaps = 36/177 (20%)
Query: 155 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 214
L ++ H AD+ ++ + +VI F K +P FR L EDQI LLK +A+E+ + N +F +
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283
Query: 215 QNFLCG--PLRYTIEDGARAPY----------------------------------LTDR 238
++ CG +Y + D +A + DR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343
Query: 239 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQ 295
PGV I+ +Q+ ++ TLQ+YI+ + P LYAK++ LA+LRS+NE + Q
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPPGSHLLYAKMIQKLADLRSLNEEHSKQ 400
>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
sapiens]
Length = 410
Score = 139 bits (350), Expect = 3e-33
Identities = 103/347 (29%), Positives = 157/347 (45%), Gaps = 57/347 (16%)
Query: 6 DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
D+ CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ PT C + C + K R C
Sbjct: 48 DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107
Query: 64 PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
CR +KC+ GM D++L E RR K+ R+ Q + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167
Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
I AH T G+ ++Q +F P I P+ ++ L + F I T
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224
Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICH-------------IVLNTTFCLQT 214
+ +V+ F K LP+F LP EDQI LLKG +EI + L+ ++
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284
Query: 215 QNFLCGPL---------------RYTIED------GARAPYLTDRPGVTQRDEIDQLQEE 253
+ G L + ++D A TDR G+ D+I++ QE
Sbjct: 285 EQLKNGGLGVVSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEA 344
Query: 254 MALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 300
L + Y+ R+ + KLL + +LR I + + H++
Sbjct: 345 YLLAFEHYV--NHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMK 389
>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
sapiens]
Length = 490
Score = 134 bits (338), Expect = 8e-32
Identities = 80/214 (37%), Positives = 112/214 (52%), Gaps = 21/214 (9%)
Query: 6 DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
D+ CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ PT C + C + K R C
Sbjct: 48 DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107
Query: 64 PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
CR +KC+ GM D++L E RR K+ R+ Q + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167
Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
I AH T G+ ++Q +F P I P+ ++ L + F I T
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224
Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 201
+ +V+ F K LP+F LP EDQI LLKG +EI
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEI 258
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 129 bits (324), Expect = 3e-30
Identities = 96/340 (28%), Positives = 158/340 (46%), Gaps = 52/340 (15%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 88 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + L+ E ELI + AH E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F ++ ++ + L F++++T +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257
Query: 191 ISLLKGAAVEICHIVLNTTFC----------------LQTQNFLCGPLRYTI-------- 226
I+LLK A ++I + + T + Q N GPL +
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLL 317
Query: 227 ---EDGARAPYLT-------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYA 276
D A L+ DR + Q D +D LQE + L+ Y++ +RRP ++
Sbjct: 318 PLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFP 375
Query: 277 KLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 312
K+L + +LRSI+ ++ I G +M PL+QE+
Sbjct: 376 KMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 129 bits (324), Expect = 3e-30
Identities = 96/340 (28%), Positives = 158/340 (46%), Gaps = 52/340 (15%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 83 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + L+ E ELI + AH E
Sbjct: 143 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 192
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F ++ ++ + L F++++T +++ ++F K LP F +L I DQ
Sbjct: 193 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 252
Query: 191 ISLLKGAAVEICHIVLNTTFC----------------LQTQNFLCGPLRYTI-------- 226
I+LLK A ++I + + T + Q N GPL +
Sbjct: 253 ITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLL 312
Query: 227 ---EDGARAPYLT-------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYA 276
D A L+ DR + Q D +D LQE + L+ Y++ +RRP ++
Sbjct: 313 PLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFP 370
Query: 277 KLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 312
K+L + +LRSI+ ++ I G +M PL+QE+
Sbjct: 371 KMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 408
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 129 bits (324), Expect = 3e-30
Identities = 96/340 (28%), Positives = 158/340 (46%), Gaps = 52/340 (15%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 88 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + L+ E ELI + AH E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F ++ ++ + L F++++T +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257
Query: 191 ISLLKGAAVEICHIVLNTTFC----------------LQTQNFLCGPLRYTI-------- 226
I+LLK A ++I + + T + Q N GPL +
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLL 317
Query: 227 ---EDGARAPYLT-------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYA 276
D A L+ DR + Q D +D LQE + L+ Y++ +RRP ++
Sbjct: 318 PLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPHMFP 375
Query: 277 KLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 312
K+L + +LRSI+ ++ I G +M PL+QE+
Sbjct: 376 KMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,538,676
Number of Sequences: 37866
Number of extensions: 494225
Number of successful extensions: 2140
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1827
Number of HSP's gapped (non-prelim): 252
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.