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Search of human proteins with 117938752
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117938752 constitutive androstane receptor isoform 2 [Homo
sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa... 711 0.0
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa... 704 0.0
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi... 697 0.0
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa... 630 0.0
gi|117938750 constitutive androstane receptor isoform 10 [Homo s... 620 e-178
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa... 614 e-176
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa... 610 e-175
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa... 608 e-174
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa... 606 e-173
gi|117938738 constitutive androstane receptor isoform 12 [Homo s... 547 e-156
gi|117938748 constitutive androstane receptor isoform 14 [Homo s... 540 e-153
gi|117938744 constitutive androstane receptor isoform 13 [Homo s... 533 e-152
gi|117938732 constitutive androstane receptor isoform 11 [Homo s... 529 e-150
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa... 525 e-149
gi|117938742 constitutive androstane receptor isoform 15 [Homo s... 448 e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof... 297 8e-81
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof... 286 3e-77
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof... 286 3e-77
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso... 182 4e-46
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso... 182 4e-46
gi|189491771 thyroid hormone receptor, beta [Homo sapiens] 166 2e-41
gi|189491769 thyroid hormone receptor, beta [Homo sapiens] 166 2e-41
gi|40806162 thyroid hormone receptor, beta [Homo sapiens] 166 2e-41
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo... 160 1e-39
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi... 158 8e-39
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 154 1e-37
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 154 1e-37
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 154 1e-37
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 154 1e-37
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 154 1e-37
>gi|117938752 constitutive androstane receptor isoform 2 [Homo
sapiens]
Length = 352
Score = 711 bits (1834), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
Query: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
>gi|117938756 constitutive androstane receptor isoform 1 [Homo
sapiens]
Length = 357
Score = 704 bits (1818), Expect = 0.0
Identities = 352/357 (98%), Positives = 352/357 (98%), Gaps = 5/357 (1%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300
Query: 296 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357
>gi|4826661 constitutive androstane receptor isoform 3 [Homo
sapiens]
Length = 348
Score = 697 bits (1799), Expect = 0.0
Identities = 348/352 (98%), Positives = 348/352 (98%), Gaps = 4/352 (1%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 296
Query: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 297 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
>gi|117938746 constitutive androstane receptor isoform 7 [Homo
sapiens]
Length = 339
Score = 630 bits (1624), Expect = 0.0
Identities = 310/310 (100%), Positives = 310/310 (100%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
Query: 301 KGQQRRPRDR 310
KGQQRRPRDR
Sbjct: 301 KGQQRRPRDR 310
>gi|117938750 constitutive androstane receptor isoform 10 [Homo
sapiens]
Length = 319
Score = 620 bits (1600), Expect = e-178
Identities = 313/317 (98%), Positives = 313/317 (98%), Gaps = 4/317 (1%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242
Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 335
RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ
Sbjct: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 302
Query: 336 HIQGLSAMMPLLQEICS 352
HIQGLSAMMPLLQEICS
Sbjct: 303 HIQGLSAMMPLLQEICS 319
>gi|117938736 constitutive androstane receptor isoform 9 [Homo
sapiens]
Length = 324
Score = 614 bits (1584), Expect = e-176
Identities = 313/322 (97%), Positives = 313/322 (97%), Gaps = 9/322 (2%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242
Query: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 330
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY
Sbjct: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAY 302
Query: 331 GYQIQHIQGLSAMMPLLQEICS 352
GYQIQHIQGLSAMMPLLQEICS
Sbjct: 303 GYQIQHIQGLSAMMPLLQEICS 324
>gi|117938729 constitutive androstane receptor isoform 6 [Homo
sapiens]
Length = 340
Score = 610 bits (1573), Expect = e-175
Identities = 306/315 (97%), Positives = 306/315 (97%), Gaps = 9/315 (2%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295
EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP DRPGVTQRDEIDQLQEEMALT
Sbjct: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 296
Query: 296 LQSYIKGQQRRPRDR 310
LQSYIKGQQRRPRDR
Sbjct: 297 LQSYIKGQQRRPRDR 311
>gi|117938754 constitutive androstane receptor isoform 4 [Homo
sapiens]
Length = 314
Score = 608 bits (1568), Expect = e-174
Identities = 310/352 (88%), Positives = 311/352 (88%), Gaps = 38/352 (10%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
A + DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 232 -----------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYI 262
Query: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 263 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314
>gi|117938734 constitutive androstane receptor isoform 5 [Homo
sapiens]
Length = 309
Score = 606 bits (1562), Expect = e-173
Identities = 309/352 (87%), Positives = 309/352 (87%), Gaps = 43/352 (12%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 232 ----------------------------------DRPGVTQRDEIDQLQEEMALTLQSYI 257
Query: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352
KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 258 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 309
>gi|117938738 constitutive androstane receptor isoform 12 [Homo
sapiens]
Length = 315
Score = 547 bits (1409), Expect = e-156
Identities = 275/280 (98%), Positives = 275/280 (98%), Gaps = 5/280 (1%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274
NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP
Sbjct: 187 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 246
Query: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286
>gi|117938748 constitutive androstane receptor isoform 14 [Homo
sapiens]
Length = 306
Score = 540 bits (1390), Expect = e-153
Identities = 271/275 (98%), Positives = 271/275 (98%), Gaps = 4/275 (1%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 242
Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 243 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277
>gi|117938744 constitutive androstane receptor isoform 13 [Homo
sapiens]
Length = 311
Score = 533 bits (1374), Expect = e-152
Identities = 271/280 (96%), Positives = 271/280 (96%), Gaps = 9/280 (3%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 274
NFLCGPLRYTIEDGAR VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP
Sbjct: 187 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 242
Query: 275 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 243 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282
>gi|117938732 constitutive androstane receptor isoform 11 [Homo
sapiens]
Length = 280
Score = 529 bits (1363), Expect = e-150
Identities = 274/317 (86%), Positives = 274/317 (86%), Gaps = 43/317 (13%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
NFLCGPLRYTIEDGAR D
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203
Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 335
RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ
Sbjct: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQ 263
Query: 336 HIQGLSAMMPLLQEICS 352
HIQGLSAMMPLLQEICS
Sbjct: 264 HIQGLSAMMPLLQEICS 280
>gi|117938740 constitutive androstane receptor isoform 8 [Homo
sapiens]
Length = 296
Score = 525 bits (1352), Expect = e-149
Identities = 267/310 (86%), Positives = 267/310 (86%), Gaps = 43/310 (13%)
Query: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1 MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
Query: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61 RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240
VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231
Query: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300
DRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 232 ----------------------------------DRPGVTQRDEIDQLQEEMALTLQSYI 257
Query: 301 KGQQRRPRDR 310
KGQQRRPRDR
Sbjct: 258 KGQQRRPRDR 267
>gi|117938742 constitutive androstane receptor isoform 15 [Homo
sapiens]
Length = 267
Score = 448 bits (1153), Expect = e-126
Identities = 232/275 (84%), Positives = 232/275 (84%), Gaps = 43/275 (15%)
Query: 36 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7 RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
Query: 96 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67 QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
Query: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275
NFLCGPLRYTIEDGAR D
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203
Query: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310
RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
3 [Homo sapiens]
Length = 397
Score = 297 bits (761), Expect = 8e-81
Identities = 161/356 (45%), Positives = 223/356 (62%), Gaps = 21/356 (5%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
C VCGD+ATGYHFN +TCEGCKGFFRR + ++ CPF G+CE+++ RR C ACRL+
Sbjct: 41 CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100
Query: 70 KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
KCL++GM+K+MI+S EA+ RRA ++++++T Q L++EQ +IR L+ A +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160
Query: 124 HMGTMFEQFVQFRPPAHLFIHHQPLPTLAP--------VLPLVTHFADINTFMVLQVIKF 175
T F F FR L + P + L+ H AD++T+M +I F
Sbjct: 161 TFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISF 220
Query: 176 TKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPT 235
K + FR LPIEDQISLLKGAA E+C + NT F +T + CG L Y +ED A
Sbjct: 221 AKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG---- 276
Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALT 295
GFQ LE + FH L+KLQL E EYVL+ A++LFSPDRPGV Q +DQLQE+ A+T
Sbjct: 277 -GFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAIT 335
Query: 296 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 350
L+SYI+ + +P RFL+ K++ +L ELRSIN + ++ IQ + PL+QE+
Sbjct: 336 LKSYIECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 391
>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
2 [Homo sapiens]
Length = 473
Score = 286 bits (731), Expect = 3e-77
Identities = 164/393 (41%), Positives = 226/393 (57%), Gaps = 58/393 (14%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
C VCGD+ATGYHFN +TCEGCKGFFRR + ++ CPF G+CE+++ RR C ACRL+
Sbjct: 80 CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 139
Query: 70 KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
KCL++GM+K+MI+S EA+ RRA ++++++T Q L++EQ +IR L+ A +
Sbjct: 140 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 199
Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
T F F FR P L + P AP
Sbjct: 200 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 259
Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
+ L+ H AD++T+M +I F K + FR LPIEDQISLLKGAA
Sbjct: 260 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 319
Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQL 258
E+C + NT F +T + CG L Y +ED A GFQ LE + FH L+KLQL
Sbjct: 320 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-----GFQQLLLEPMLKFHYMLKKLQL 374
Query: 259 QEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLG 318
E EYVL+ A++LFSPDRPGV Q +DQLQE+ A+TL+SYI+ + +P RFL+ K++
Sbjct: 375 HEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMA 434
Query: 319 LLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 350
+L ELRSIN + ++ IQ + PL+QE+
Sbjct: 435 MLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 467
>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
1 [Homo sapiens]
Length = 434
Score = 286 bits (731), Expect = 3e-77
Identities = 164/393 (41%), Positives = 226/393 (57%), Gaps = 58/393 (14%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
C VCGD+ATGYHFN +TCEGCKGFFRR + ++ CPF G+CE+++ RR C ACRL+
Sbjct: 41 CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100
Query: 70 KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
KCL++GM+K+MI+S EA+ RRA ++++++T Q L++EQ +IR L+ A +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160
Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
T F F FR P L + P AP
Sbjct: 161 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 220
Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
+ L+ H AD++T+M +I F K + FR LPIEDQISLLKGAA
Sbjct: 221 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 280
Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQL 258
E+C + NT F +T + CG L Y +ED A GFQ LE + FH L+KLQL
Sbjct: 281 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-----GFQQLLLEPMLKFHYMLKKLQL 335
Query: 259 QEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLG 318
E EYVL+ A++LFSPDRPGV Q +DQLQE+ A+TL+SYI+ + +P RFL+ K++
Sbjct: 336 HEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMA 395
Query: 319 LLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 350
+L ELRSIN + ++ IQ + PL+QE+
Sbjct: 396 MLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 428
>gi|194294519 nuclear receptor subfamily 1, group H, member 3
isoform c [Homo sapiens]
Length = 402
Score = 182 bits (462), Expect = 4e-46
Identities = 116/356 (32%), Positives = 182/356 (51%), Gaps = 27/356 (7%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VCGD+A+G+H+N L+CEGCKGFFRR+V K C G C + RR C CRL+K
Sbjct: 53 CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 112
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
C AGMR++ +LS E + L++ K+ + RA P QLS EQ +I L
Sbjct: 113 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 172
Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
+ A + F ++ P P H + HF ++ V +++ F
Sbjct: 173 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 227
Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVSPT 235
K LP F L EDQI+LLK +A+E+ + + + +++ Y ED A+
Sbjct: 228 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAK---- 283
Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALT 295
G QVEF+ +F F + +LQL + E+ LL A+++FS DRP V + ++++LQ
Sbjct: 284 AGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEA 343
Query: 296 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 350
L +Y+ P DR ++ ++L L LR+++ + Q+ ++ + PLL EI
Sbjct: 344 LHAYV--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 397
>gi|194294517 nuclear receptor subfamily 1, group H, member 3
isoform a [Homo sapiens]
Length = 447
Score = 182 bits (462), Expect = 4e-46
Identities = 116/356 (32%), Positives = 182/356 (51%), Gaps = 27/356 (7%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VCGD+A+G+H+N L+CEGCKGFFRR+V K C G C + RR C CRL+K
Sbjct: 98 CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 157
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
C AGMR++ +LS E + L++ K+ + RA P QLS EQ +I L
Sbjct: 158 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 217
Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
+ A + F ++ P P H + HF ++ V +++ F
Sbjct: 218 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 272
Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVSPT 235
K LP F L EDQI+LLK +A+E+ + + + +++ Y ED A+
Sbjct: 273 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAK---- 328
Query: 236 VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALT 295
G QVEF+ +F F + +LQL + E+ LL A+++FS DRP V + ++++LQ
Sbjct: 329 AGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEA 388
Query: 296 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 350
L +Y+ P DR ++ ++L L LR+++ + Q+ ++ + PLL EI
Sbjct: 389 LHAYV--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 442
>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 166 bits (421), Expect = 2e-41
Identities = 116/354 (32%), Positives = 174/354 (49%), Gaps = 33/354 (9%)
Query: 5 EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
+DEL CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ P +C + G C + K R
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160
Query: 63 CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
C CR +KC+ GM D++L +R + R ++ +L K E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220
Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
LI+T+ AH T G+ ++Q +F P I P+ AP L +HF I
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276
Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
T + +V+ F K LP+F LP EDQI LLKG +EI + + +++ L G +
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336
Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDE 284
T R G + +F +L L + E LL A+ L S DRPG+ +
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVER 391
Query: 285 IDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 338
I++ Q+ L + YI R+ + KLL + +LR I + + H++
Sbjct: 392 IEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443
>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 166 bits (421), Expect = 2e-41
Identities = 116/354 (32%), Positives = 174/354 (49%), Gaps = 33/354 (9%)
Query: 5 EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
+DEL CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ P +C + G C + K R
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160
Query: 63 CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
C CR +KC+ GM D++L +R + R ++ +L K E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220
Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
LI+T+ AH T G+ ++Q +F P I P+ AP L +HF I
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276
Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
T + +V+ F K LP+F LP EDQI LLKG +EI + + +++ L G +
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336
Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDE 284
T R G + +F +L L + E LL A+ L S DRPG+ +
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVER 391
Query: 285 IDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 338
I++ Q+ L + YI R+ + KLL + +LR I + + H++
Sbjct: 392 IEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443
>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 166 bits (421), Expect = 2e-41
Identities = 116/354 (32%), Positives = 174/354 (49%), Gaps = 33/354 (9%)
Query: 5 EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
+DEL CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ P +C + G C + K R
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160
Query: 63 CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
C CR +KC+ GM D++L +R + R ++ +L K E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220
Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
LI+T+ AH T G+ ++Q +F P I P+ AP L +HF I
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276
Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
T + +V+ F K LP+F LP EDQI LLKG +EI + + +++ L G +
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336
Query: 225 TIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDE 284
T R G + +F +L L + E LL A+ L S DRPG+ +
Sbjct: 337 T-----RGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVER 391
Query: 285 IDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 338
I++ Q+ L + YI R+ + KLL + +LR I + + H++
Sbjct: 392 IEKYQDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443
>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
sapiens]
Length = 472
Score = 160 bits (406), Expect = 1e-39
Identities = 110/335 (32%), Positives = 174/335 (51%), Gaps = 27/335 (8%)
Query: 6 DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPA 65
DEL CVVCGD+A+GYH+NALTCEGCKGFFRR+++K+ C G+C + RR C
Sbjct: 124 DEL--CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQE 181
Query: 66 CRLQKCLDAGMRKDMILS-AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRH 124
CRL+KC + GM + +L+ + + R K ++ A QT ++++ E + + T+
Sbjct: 182 CRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQT---VNEDSEGRDLRQVTSTTKS 238
Query: 125 MGTMFEQFVQFRPPAHLFI---HHQPLPTLAPVLPLVTHFADINTFMVLQ---------V 172
E + H + + Q +P L F+ F++L +
Sbjct: 239 CREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVL 298
Query: 173 IKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARV 232
++FTK LP F++L EDQI+LLKG+AVE + F + + L I +
Sbjct: 299 VEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNS--- 355
Query: 233 SPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEM 292
G E++ +F F+ ++ +L++ + EY LL A+ + SPDR + R+ +++LQE +
Sbjct: 356 ----GISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPL 411
Query: 293 ALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 327
LQ K Q P + +A LLG L ELR+ N
Sbjct: 412 LDVLQKLCKIHQ--PENPQHFACLLGRLTELRTFN 444
>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
sapiens]
Length = 410
Score = 158 bits (399), Expect = 8e-39
Identities = 112/355 (31%), Positives = 171/355 (48%), Gaps = 35/355 (9%)
Query: 6 DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
D+ CVVCGD+ATGYH+ +TCEGCKGFFRRT+ K++ PT C + C + K R C
Sbjct: 48 DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107
Query: 64 PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
CR +KC+ GM D++L E RR K+ R+ Q + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167
Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
I AH T G+ ++Q +F P I P+ ++ L + F I T
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224
Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPL---R 223
+ +V+ F K LP+F LP EDQI LLKG +EI + + ++ L G + R
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284
Query: 224 YTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRD 283
+++G G V + +F +L L + E LL A+ L S DR G+ D
Sbjct: 285 EQLKNG-------GLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVD 336
Query: 284 EIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 338
+I++ QE L + Y+ R+ + KLL + +LR I + + H++
Sbjct: 337 KIEKSQEAYLLAFEHYV--NHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMK 389
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 154 bits (388), Expect = 1e-37
Identities = 103/347 (29%), Positives = 173/347 (49%), Gaps = 28/347 (8%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 88 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + L+ E ELI + AH E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F ++ ++ + L F++++T +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257
Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
I+LLK A ++I + + T + + T DG ++ T F +L+F
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 310
Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
F L L++ + E LL+A+ L DR + Q D +D LQE + L+ Y++ +RRP
Sbjct: 311 AFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRP 368
Query: 308 RDRFLYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 350
++ K+L + +LRSI+ ++ I G +M PL+QE+
Sbjct: 369 SRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 154 bits (388), Expect = 1e-37
Identities = 103/347 (29%), Positives = 173/347 (49%), Gaps = 28/347 (8%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 83 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + L+ E ELI + AH E
Sbjct: 143 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 192
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F ++ ++ + L F++++T +++ ++F K LP F +L I DQ
Sbjct: 193 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 252
Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
I+LLK A ++I + + T + + T DG ++ T F +L+F
Sbjct: 253 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 305
Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
F L L++ + E LL+A+ L DR + Q D +D LQE + L+ Y++ +RRP
Sbjct: 306 AFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRP 363
Query: 308 RDRFLYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 350
++ K+L + +LRSI+ ++ I G +M PL+QE+
Sbjct: 364 SRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 408
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 154 bits (388), Expect = 1e-37
Identities = 103/347 (29%), Positives = 173/347 (49%), Gaps = 28/347 (8%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 88 CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + L+ E ELI + AH E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F ++ ++ + L F++++T +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257
Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
I+LLK A ++I + + T + + T DG ++ T F +L+F
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 310
Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
F L L++ + E LL+A+ L DR + Q D +D LQE + L+ Y++ +RRP
Sbjct: 311 AFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRP 368
Query: 308 RDRFLYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 350
++ K+L + +LRSI+ ++ I G +M PL+QE+
Sbjct: 369 SRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 154 bits (388), Expect = 1e-37
Identities = 95/320 (29%), Positives = 163/320 (50%), Gaps = 22/320 (6%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ +CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 79 CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 138
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + +LS + EELI + AH E
Sbjct: 139 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 188
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F + + L L F+++ T ++++++F K LP F L I DQ
Sbjct: 189 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 248
Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
I+LLK A ++I + + T + + T DG ++ T F +L+F
Sbjct: 249 ITLLKAACLDILMLRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 301
Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
F G L L++ + E LL+A+ L DR + + +++D+LQE + L+ Y ++RRP
Sbjct: 302 AFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLY--ARRRRP 359
Query: 308 RDRFLYAKLLGLLAELRSIN 327
+++ ++L + +LR I+
Sbjct: 360 SQPYMFPRMLMKITDLRGIS 379
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 154 bits (388), Expect = 1e-37
Identities = 95/320 (29%), Positives = 163/320 (50%), Gaps = 22/320 (6%)
Query: 11 CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
C VC D+++GYH+ +CEGCKGFFRR++ K++ TC +C ++K R C CRLQK
Sbjct: 90 CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 149
Query: 71 CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
C + GM K+ + + ++ K+ + +LS + EELI + AH E
Sbjct: 150 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 199
Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
F + + L L F+++ T ++++++F K LP F L I DQ
Sbjct: 200 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 259
Query: 191 ISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEF---LELLF 247
I+LLK A ++I + + T + + T DG ++ T F +L+F
Sbjct: 260 ITLLKAACLDILMLRICTRYTPEQDTM-------TFSDGLTLNRTQMHNAGFGPLTDLVF 312
Query: 248 HFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 307
F G L L++ + E LL+A+ L DR + + +++D+LQE + L+ Y ++RRP
Sbjct: 313 AFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLY--ARRRRP 370
Query: 308 RDRFLYAKLLGLLAELRSIN 327
+++ ++L + +LR I+
Sbjct: 371 SQPYMFPRMLMKITDLRGIS 390
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,926,048
Number of Sequences: 37866
Number of extensions: 553905
Number of successful extensions: 2371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2024
Number of HSP's gapped (non-prelim): 204
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.