Search of human proteins with 117938742

Search of human proteins with 117938742

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938742 constitutive androstane receptor isoform 15 [Homo
sapiens]
         (267 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   547   e-156
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   535   e-152
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   528   e-150
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   526   e-149
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   524   e-149
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   514   e-146
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   514   e-146
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   481   e-136
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   469   e-132
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   463   e-131
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   461   e-130
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   459   e-130
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   450   e-127
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   448   e-126
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   446   e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   165   4e-41
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   153   1e-37
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   153   1e-37
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]             89   3e-18
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]             89   3e-18
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]              89   3e-18
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ...    87   1e-17
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s...    87   1e-17
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...    83   2e-16
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...    83   2e-16
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...    79   3e-15
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...    79   3e-15
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]    75   5e-14
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]     75   5e-14
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]      75   5e-14

>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  547 bits (1409), Expect = e-156
 Identities = 267/267 (100%), Positives = 267/267 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSP 240
           FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSP
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSP 240

Query: 241 GTPWIHWSGKMLGPKIGPGSKGAQWLQ 267
           GTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 241 GTPWIHWSGKMLGPKIGPGSKGAQWLQ 267


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  535 bits (1379), Expect = e-152
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIH 246
           NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIH
Sbjct: 216 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIH 275

Query: 247 WSGKMLGPKIGPGSKGAQWLQ 267
           WSGKMLGPKIGPGSKGAQWLQ
Sbjct: 276 WSGKMLGPKIGPGSKGAQWLQ 296


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  528 bits (1359), Expect = e-150
 Identities = 267/306 (87%), Positives = 267/306 (87%), Gaps = 39/306 (12%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK 261
            DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSK 300

Query: 262 GAQWLQ 267
           GAQWLQ
Sbjct: 301 GAQWLQ 306


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  526 bits (1354), Expect = e-149
 Identities = 267/311 (85%), Positives = 267/311 (85%), Gaps = 44/311 (14%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 ------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKI 256
                 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKI
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKI 300

Query: 257 GPGSKGAQWLQ 267
           GPGSKGAQWLQ
Sbjct: 301 GPGSKGAQWLQ 311


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  524 bits (1350), Expect = e-149
 Identities = 267/315 (84%), Positives = 267/315 (84%), Gaps = 48/315 (15%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAM 240

Query: 203 ----------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKML 252
                     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKML
Sbjct: 241 ALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKML 300

Query: 253 GPKIGPGSKGAQWLQ 267
           GPKIGPGSKGAQWLQ
Sbjct: 301 GPKIGPGSKGAQWLQ 315


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  514 bits (1325), Expect = e-146
 Identities = 261/304 (85%), Positives = 261/304 (85%), Gaps = 43/304 (14%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203
           NFLCGPLRYTIEDGAR                                           D
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275

Query: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 263
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGA 335

Query: 264 QWLQ 267
           QWLQ
Sbjct: 336 QWLQ 339


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  514 bits (1324), Expect = e-146
 Identities = 261/305 (85%), Positives = 261/305 (85%), Gaps = 44/305 (14%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202
           NFLCGPLRYTIEDGAR                                            
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275

Query: 203 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 262
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG
Sbjct: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 335

Query: 263 AQWLQ 267
           AQWLQ
Sbjct: 336 AQWLQ 340


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  481 bits (1237), Expect = e-136
 Identities = 238/238 (100%), Positives = 238/238 (100%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  469 bits (1207), Expect = e-132
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 216 NFLCGPLRYTIEDGARDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 267


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  463 bits (1191), Expect = e-131
 Identities = 232/237 (97%), Positives = 232/237 (97%), Gaps = 5/237 (2%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           NFLCGPLRYTIEDGAR     DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 216 NFLCGPLRYTIEDGARAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 272


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  461 bits (1187), Expect = e-130
 Identities = 238/277 (85%), Positives = 238/277 (85%), Gaps = 39/277 (14%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 -DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
            DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  459 bits (1182), Expect = e-130
 Identities = 238/282 (84%), Positives = 238/282 (84%), Gaps = 44/282 (15%)

Query: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60
           MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL
Sbjct: 1   MLPKRSRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALAL 60

Query: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120
           RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP
Sbjct: 61  RRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLP 120

Query: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180
           TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT
Sbjct: 121 TLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTT 180

Query: 181 FCLQTQNFLCGPLRYTIEDGAR-------------------------------------- 202
           FCLQTQNFLCGPLRYTIEDGAR                                      
Sbjct: 181 FCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFS 240

Query: 203 ------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
                 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 241 PAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  450 bits (1157), Expect = e-127
 Identities = 232/271 (85%), Positives = 232/271 (85%), Gaps = 39/271 (14%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 207
           NFLCGPLRYTIEDGAR                                       DRPGV
Sbjct: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 306


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  448 bits (1153), Expect = e-126
 Identities = 232/275 (84%), Positives = 232/275 (84%), Gaps = 43/275 (15%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------D 203
           NFLCGPLRYTIEDGAR                                           D
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPD 275

Query: 204 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
           RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 RPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 310


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  446 bits (1148), Expect = e-126
 Identities = 232/280 (82%), Positives = 232/280 (82%), Gaps = 48/280 (17%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215

Query: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202
           NFLCGPLRYTIEDGAR                                            
Sbjct: 216 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 275

Query: 203 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 276 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 315


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  165 bits (417), Expect = 4e-41
 Identities = 102/285 (35%), Positives = 147/285 (51%), Gaps = 53/285 (18%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPL 119
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR    L      +
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRVSLQLRGEDGSV 185

Query: 120 PTLAP--------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVE 171
               P        +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA E
Sbjct: 186 WNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFE 245

Query: 172 ICHIVLNTTFCLQTQNFLCGPLRYTIEDGA------------------------------ 201
           +C +  NT F  +T  + CG L Y +ED A                              
Sbjct: 246 LCQLRFNTVFNAETGTWECGRLSYCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVL 305

Query: 202 --------RDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238
                    DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  R
Sbjct: 306 MQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHR 350


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  153 bits (387), Expect = 1e-37
 Identities = 105/322 (32%), Positives = 150/322 (46%), Gaps = 90/322 (27%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 105 RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 164

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 165 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 224

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 225 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 284

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 285 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 344

Query: 195 YTIEDGA--------------------------------------RDRPGVTQRDEIDQL 216
           Y +ED A                                       DRPGV Q   +DQL
Sbjct: 345 YCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQL 404

Query: 217 QEEMALTLQSYIKGQQRRPRDR 238
           QE+ A+TL+SYI+  + +P  R
Sbjct: 405 QEQFAITLKSYIECNRPQPAHR 426


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  153 bits (387), Expect = 1e-37
 Identities = 105/322 (32%), Positives = 150/322 (46%), Gaps = 90/322 (27%)

Query: 7   RRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQ 65
           RR + ++    CPF  G+CE+++  RR C ACRL+KCL++GM+K+MI+S EA+  RRA  
Sbjct: 66  RRAMKRNARLRCPFRKGACEITRKTRRQCQACRLRKCLESGMKKEMIMSDEAVEERRALI 125

Query: 66  AQRRAQQTPVQ------LSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQ-P 118
            ++++++T  Q      L++EQ  +IR L+ A  +   T F  F  FR P  L    + P
Sbjct: 126 KRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMKTFDTTFSHFKNFRLPGVLSSGCELP 185

Query: 119 LPTLAP--------------------------------------------VLPLVTHFAD 134
               AP                                            +  L+ H AD
Sbjct: 186 ESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMAD 245

Query: 135 INTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLR 194
           ++T+M   +I F K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L 
Sbjct: 246 MSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLS 305

Query: 195 YTIEDGA--------------------------------------RDRPGVTQRDEIDQL 216
           Y +ED A                                       DRPGV Q   +DQL
Sbjct: 306 YCLEDTAGGFQQLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQL 365

Query: 217 QEEMALTLQSYIKGQQRRPRDR 238
           QE+ A+TL+SYI+  + +P  R
Sbjct: 366 QEQFAITLKSYIECNRPQPAHR 387


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 62/185 (33%), Positives = 91/185 (49%), Gaps = 23/185 (12%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEI 172
             +EI
Sbjct: 308 CCMEI 312


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 62/185 (33%), Positives = 91/185 (49%), Gaps = 23/185 (12%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEI 172
             +EI
Sbjct: 308 CCMEI 312


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 62/185 (33%), Positives = 91/185 (49%), Gaps = 23/185 (12%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAK 64
           RRT+ K++ P+  C + G C + K  R  C  CR +KC+  GM  D++L       +R  
Sbjct: 132 RRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKL 191

Query: 65  QAQRRAQQTPVQLSK----------EQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
             + R ++   +L K          E+ ELI+T+  AH  T   G+ ++Q  +F P    
Sbjct: 192 IEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPED-- 249

Query: 113 FIHHQPLPTLAPV-----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKG 167
            I   P+   AP      L   +HF  I T  + +V+ F K LP+F  LP EDQI LLKG
Sbjct: 250 -IGQAPIVN-APEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKG 307

Query: 168 AAVEI 172
             +EI
Sbjct: 308 CCMEI 312


>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 41/151 (27%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGAR---------------------------------------DR 204
            ++ CG    +Y + D  +                                       DR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343

Query: 205 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 235
           PGV     I+ +Q+ ++ TLQ+YI+ +   P
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPP 374


>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 5/111 (4%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ +    TCPF G C ++K  RRHC ACRL++C+D GM K+ IL+ E +  +R    
Sbjct: 49  RRSMKRKALFTCPFNGDCRITKDNRRHCQACRLKRCVDIGMMKEFILTDEEVQRKREMIL 108

Query: 67  QRRAQQT-----PVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHL 112
           +R+ ++        +LS+EQ+ +I  LL AH +     +  F QFRPP  +
Sbjct: 109 KRKEEEALKDSLRPKLSEEQQRIIAILLDAHHKTYDPTYSDFCQFRPPVRV 159



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 40/151 (26%), Positives = 67/151 (44%), Gaps = 41/151 (27%)

Query: 126 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 185
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 186 QNFLCG--PLRYTIEDGAR---------------------------------------DR 204
            ++ CG    +Y + D  +                                       DR
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR 343

Query: 205 PGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 235
           PGV     I+ +Q+ ++ TLQ+YI+ +   P
Sbjct: 344 PGVQDAALIEAIQDRLSNTLQTYIRCRHPPP 374


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 59/184 (32%), Positives = 87/184 (47%), Gaps = 21/184 (11%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILS---------- 54
           RRT+ K++ PT  C +   C + K  R  C  CR +KC+  GM  D++L           
Sbjct: 78  RRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKL 137

Query: 55  AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
            E    RR K+   R+ Q   + + E+ +LI     AH  T   G+ ++Q  +F P    
Sbjct: 138 IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDD-- 195

Query: 113 FIHHQPLPTLAPV----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGA 168
            I   P+ ++       L   + F  I T  + +V+ F K LP+F  LP EDQI LLKG 
Sbjct: 196 -IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGC 254

Query: 169 AVEI 172
            +EI
Sbjct: 255 CMEI 258


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 59/184 (32%), Positives = 87/184 (47%), Gaps = 21/184 (11%)

Query: 7   RRTVSKSIGPT--CPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILS---------- 54
           RRT+ K++ PT  C +   C + K  R  C  CR +KC+  GM  D++L           
Sbjct: 78  RRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRKL 137

Query: 55  AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAH--TRHMGTMFEQFVQFRPPAHL 112
            E    RR K+   R+ Q   + + E+ +LI     AH  T   G+ ++Q  +F P    
Sbjct: 138 IEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHIATEAHRSTNAQGSHWKQRRKFLPDD-- 195

Query: 113 FIHHQPLPTLAPV----LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGA 168
            I   P+ ++       L   + F  I T  + +V+ F K LP+F  LP EDQI LLKG 
Sbjct: 196 -IGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSELPCEDQIILLKGC 254

Query: 169 AVEI 172
            +EI
Sbjct: 255 CMEI 258


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score = 79.3 bits (194), Expect = 3e-15
 Identities = 57/180 (31%), Positives = 83/180 (46%), Gaps = 19/180 (10%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 78  RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 137

Query: 67  QR----------RAQQTP---VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 138 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 197

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 198 DPHSREARQ-----QRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 252


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score = 79.3 bits (194), Expect = 3e-15
 Identities = 57/180 (31%), Positives = 83/180 (46%), Gaps = 19/180 (10%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR+V K     C   G C +    RR C  CRL+KC  AGMR++ +LS E + L++ K+ 
Sbjct: 123 RRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQ 182

Query: 67  QR----------RAQQTP---VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP-PAHL 112
           +           RA   P    QLS EQ  +I  L+ A  +     F   ++  P P   
Sbjct: 183 EEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAP 242

Query: 113 FIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEI 172
             H +             HF ++    V +++ F K LP F  L  EDQI+LLK +A+E+
Sbjct: 243 DPHSREARQ-----QRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEV 297


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 67/268 (25%), Positives = 113/268 (42%), Gaps = 51/268 (19%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +     
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 342

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRP 235
            Q D +D LQE +   L+ Y++  +RRP
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVR--KRRP 368


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 67/268 (25%), Positives = 113/268 (42%), Gaps = 51/268 (19%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 108 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 164

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 165 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 217

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +     
Sbjct: 218 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 277

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 278 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 337

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRP 235
            Q D +D LQE +   L+ Y++  +RRP
Sbjct: 338 EQPDRVDMLQEPLLEALKVYVR--KRRP 363


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 75.5 bits (184), Expect = 5e-14
 Identities = 67/268 (25%), Positives = 113/268 (42%), Gaps = 51/268 (19%)

Query: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66
           RR++ K++  TC    +C ++K  R  C  CRLQKC + GM K+ + +      ++ K+ 
Sbjct: 113 RRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRN---KKKKEV 169

Query: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126
            +        L+ E  ELI  +  AH        E F           ++     ++  +
Sbjct: 170 PKPECSESYTLTPEVGELIEKVRKAHQ-------ETFPALCQLGKYTTNNSSEQRVSLDI 222

Query: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFC---- 182
            L   F++++T  +++ ++F K LP F +L I DQI+LLK A ++I  + + T +     
Sbjct: 223 DLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQD 282

Query: 183 ------------LQTQNFLCGPLRYTI---------------EDG--------ARDRPGV 207
                        Q  N   GPL   +               E G          DR  +
Sbjct: 283 TMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDL 342

Query: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRP 235
            Q D +D LQE +   L+ Y++  +RRP
Sbjct: 343 EQPDRVDMLQEPLLEALKVYVR--KRRP 368


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,745,091
Number of Sequences: 37866
Number of extensions: 485847
Number of successful extensions: 2172
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1917
Number of HSP's gapped (non-prelim): 227
length of query: 267
length of database: 18,247,518
effective HSP length: 100
effective length of query: 167
effective length of database: 14,460,918
effective search space: 2414973306
effective search space used: 2414973306
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.