Guide to the Human Genome
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Search of human proteins with 117938729

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117938729 constitutive androstane receptor isoform 6 [Homo
sapiens]
         (340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   699   0.0  
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   676   0.0  
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   627   e-180
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   622   e-178
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   616   e-177
gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   616   e-176
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   610   e-175
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   605   e-173
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   591   e-169
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   556   e-158
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   539   e-153
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   537   e-153
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   525   e-149
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   514   e-146
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   448   e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   265   6e-71
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   253   2e-67
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   253   2e-67
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   168   6e-42
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   168   6e-42
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            157   1e-38
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            157   1e-38
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             157   1e-38
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   151   7e-37
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...   151   7e-37
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo...   145   5e-35
gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo ...   139   4e-33
gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo s...   139   4e-33
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   135   4e-32
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     135   4e-32

>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  699 bits (1803), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300
           LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300

Query: 301 IKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 340
           IKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 301 IKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 340


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  676 bits (1745), Expect = 0.0
 Identities = 335/344 (97%), Positives = 335/344 (97%), Gaps = 9/344 (2%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 296
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295

Query: 297 LQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 340
           LQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 296 LQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 339


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  627 bits (1616), Expect = e-180
 Identities = 311/315 (98%), Positives = 311/315 (98%), Gaps = 4/315 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 296
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300

Query: 297 LQSYIKGQQRRPRDR 311
           LQSYIKGQQRRPRDR
Sbjct: 301 LQSYIKGQQRRPRDR 315


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  622 bits (1604), Expect = e-178
 Identities = 305/305 (100%), Positives = 305/305 (100%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246

Query: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 335
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG
Sbjct: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 306

Query: 336 AQWLQ 340
           AQWLQ
Sbjct: 307 AQWLQ 311


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  616 bits (1589), Expect = e-177
 Identities = 305/309 (98%), Positives = 305/309 (98%), Gaps = 4/309 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 271
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA
Sbjct: 187 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 246

Query: 272 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP 331
           PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP
Sbjct: 247 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGP 306

Query: 332 GSKGAQWLQ 340
           GSKGAQWLQ
Sbjct: 307 GSKGAQWLQ 315


>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  616 bits (1588), Expect = e-176
 Identities = 306/311 (98%), Positives = 306/311 (98%), Gaps = 5/311 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300
           LLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALTLQSY 295

Query: 301 IKGQQRRPRDR 311
           IKGQQRRPRDR
Sbjct: 296 IKGQQRRPRDR 306


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  610 bits (1573), Expect = e-175
 Identities = 306/315 (97%), Positives = 306/315 (97%), Gaps = 9/315 (2%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 296
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 295

Query: 297 LQSYIKGQQRRPRDR 311
           LQSYIKGQQRRPRDR
Sbjct: 296 LQSYIKGQQRRPRDR 310


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  605 bits (1561), Expect = e-173
 Identities = 300/305 (98%), Positives = 300/305 (98%), Gaps = 5/305 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 241

Query: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 335
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG
Sbjct: 242 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 301

Query: 336 AQWLQ 340
           AQWLQ
Sbjct: 302 AQWLQ 306


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  591 bits (1523), Expect = e-169
 Identities = 296/340 (87%), Positives = 296/340 (87%), Gaps = 44/340 (12%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300
                                              DRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 232 -----------------------------------DRPGVTQRDEIDQLQEEMALTLQSY 256

Query: 301 IKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 340
           IKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ
Sbjct: 257 IKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKGAQWLQ 296


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  556 bits (1432), Expect = e-158
 Identities = 276/276 (100%), Positives = 276/276 (100%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246

Query: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  539 bits (1389), Expect = e-153
 Identities = 271/276 (98%), Positives = 271/276 (98%), Gaps = 5/276 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 241

Query: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 242 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  537 bits (1383), Expect = e-153
 Identities = 272/311 (87%), Positives = 272/311 (87%), Gaps = 39/311 (12%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300
                                         APYLTDRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 232 ------------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSY 261

Query: 301 IKGQQRRPRDR 311
           IKGQQRRPRDR
Sbjct: 262 IKGQQRRPRDR 272


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  525 bits (1351), Expect = e-149
 Identities = 267/311 (85%), Positives = 267/311 (85%), Gaps = 44/311 (14%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300
                                              DRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 232 -----------------------------------DRPGVTQRDEIDQLQEEMALTLQSY 256

Query: 301 IKGQQRRPRDR 311
           IKGQQRRPRDR
Sbjct: 257 IKGQQRRPRDR 267


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  514 bits (1324), Expect = e-146
 Identities = 261/305 (85%), Positives = 261/305 (85%), Gaps = 44/305 (14%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
           NFLCGPLRYTIEDGAR                                            
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202

Query: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 335
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG
Sbjct: 203 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRSPGTPWIHWSGKMLGPKIGPGSKG 262

Query: 336 AQWLQ 340
           AQWLQ
Sbjct: 263 AQWLQ 267


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  448 bits (1152), Expect = e-126
 Identities = 232/276 (84%), Positives = 232/276 (84%), Gaps = 44/276 (15%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 275
           NFLCGPLRYTIEDGAR                                            
Sbjct: 187 NFLCGPLRYTIEDGAR-------------------------------------------- 202

Query: 276 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 203 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  265 bits (676), Expect = 6e-71
 Identities = 145/316 (45%), Positives = 197/316 (62%), Gaps = 21/316 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQPLPTLAP--------VLPLVTHFADINTFMVLQVIKF 175
              T F  F  FR    L      +    P        +  L+ H AD++T+M   +I F
Sbjct: 161 TFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISF 220

Query: 176 TKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQ 235
            K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L Y +ED A  GFQ
Sbjct: 221 AKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQ 279

Query: 236 VEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMAL 295
              LE +  FH  L+KLQL E EYVL+ A++LFSP     DRPGV Q   +DQLQE+ A+
Sbjct: 280 QLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSP-----DRPGVLQHRVVDQLQEQFAI 334

Query: 296 TLQSYIKGQQRRPRDR 311
           TL+SYI+  + +P  R
Sbjct: 335 TLKSYIECNRPQPAHR 350


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  253 bits (646), Expect = 2e-67
 Identities = 148/353 (41%), Positives = 200/353 (56%), Gaps = 58/353 (16%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 80  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 139

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 140 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 199

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 200 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 259

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 260 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 319

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPE 258
            E+C +  NT F  +T  + CG L Y +ED A  GFQ   LE +  FH  L+KLQL E E
Sbjct: 320 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEE 378

Query: 259 YVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311
           YVL+ A++LFSP     DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  R
Sbjct: 379 YVLMQAISLFSP-----DRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHR 426


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  253 bits (646), Expect = 2e-67
 Identities = 148/353 (41%), Positives = 200/353 (56%), Gaps = 58/353 (16%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 161 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 220

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 221 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 280

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPE 258
            E+C +  NT F  +T  + CG L Y +ED A  GFQ   LE +  FH  L+KLQL E E
Sbjct: 281 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEE 339

Query: 259 YVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 311
           YVL+ A++LFSP     DRPGV Q   +DQLQE+ A+TL+SYI+  + +P  R
Sbjct: 340 YVLMQAISLFSP-----DRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHR 387


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  168 bits (426), Expect = 6e-42
 Identities = 106/316 (33%), Positives = 160/316 (50%), Gaps = 27/316 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 53  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 112

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 113 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 172

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 173 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 227

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQ 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+ G Q
Sbjct: 228 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQ 287

Query: 236 VEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMAL 295
           VEF+  +F F   + +LQL + E+ LL A+++FS      DRP V  + ++++LQ     
Sbjct: 288 VEFINPIFEFSRAMNELQLNDAEFALLIAISIFS-----ADRPNVQDQLQVERLQHTYVE 342

Query: 296 TLQSYIKGQQRRPRDR 311
            L +Y+      P DR
Sbjct: 343 ALHAYV--SIHHPHDR 356


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  168 bits (426), Expect = 6e-42
 Identities = 106/316 (33%), Positives = 160/316 (50%), Gaps = 27/316 (8%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 98  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 157

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 158 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 217

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 218 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 272

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQ 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+ G Q
Sbjct: 273 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQ 332

Query: 236 VEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMAL 295
           VEF+  +F F   + +LQL + E+ LL A+++FS      DRP V  + ++++LQ     
Sbjct: 333 VEFINPIFEFSRAMNELQLNDAEFALLIAISIFS-----ADRPNVQDQLQVERLQHTYVE 387

Query: 296 TLQSYIKGQQRRPRDR 311
            L +Y+      P DR
Sbjct: 388 ALHAYV--SIHHPHDR 401


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  157 bits (397), Expect = 1e-38
 Identities = 108/317 (34%), Positives = 159/317 (50%), Gaps = 32/317 (10%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRD 284
           T       G  V   + +F    +L    L + E  LL A+ L S     +DRPG+   +
Sbjct: 337 TRGQLKNGGLGV-VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMS-----SDRPGLACVE 390

Query: 285 EIDQLQEEMALTLQSYI 301
            I++ Q+   L  + YI
Sbjct: 391 RIEKYQDSFLLAFEHYI 407


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  157 bits (397), Expect = 1e-38
 Identities = 108/317 (34%), Positives = 159/317 (50%), Gaps = 32/317 (10%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRD 284
           T       G  V   + +F    +L    L + E  LL A+ L S     +DRPG+   +
Sbjct: 337 TRGQLKNGGLGV-VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMS-----SDRPGLACVE 390

Query: 285 EIDQLQEEMALTLQSYI 301
            I++ Q+   L  + YI
Sbjct: 391 RIEKYQDSFLLAFEHYI 407


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  157 bits (397), Expect = 1e-38
 Identities = 108/317 (34%), Positives = 159/317 (50%), Gaps = 32/317 (10%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRD 284
           T       G  V   + +F    +L    L + E  LL A+ L S     +DRPG+   +
Sbjct: 337 TRGQLKNGGLGV-VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMS-----SDRPGLACVE 390

Query: 285 EIDQLQEEMALTLQSYI 301
            I++ Q+   L  + YI
Sbjct: 391 RIEKYQDSFLLAFEHYI 407


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  151 bits (382), Expect = 7e-37
 Identities = 104/315 (33%), Positives = 152/315 (48%), Gaps = 28/315 (8%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTI 226
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +    
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 227 EDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEI 286
           E     G  V   + +F    +L    L + E  LL A+ L S     TDR G+   D+I
Sbjct: 285 EQLKNGGLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMS-----TDRSGLLCVDKI 338

Query: 287 DQLQEEMALTLQSYI 301
           ++ QE   L  + Y+
Sbjct: 339 EKSQEAYLLAFEHYV 353


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score =  151 bits (382), Expect = 7e-37
 Identities = 104/315 (33%), Positives = 152/315 (48%), Gaps = 28/315 (8%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTI 226
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +    
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 227 EDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEI 286
           E     G  V   + +F    +L    L + E  LL A+ L S     TDR G+   D+I
Sbjct: 285 EQLKNGGLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMS-----TDRSGLLCVDKI 338

Query: 287 DQLQEEMALTLQSYI 301
           ++ QE   L  + Y+
Sbjct: 339 EKSQEAYLLAFEHYV 353


>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
           sapiens]
          Length = 472

 Score =  145 bits (366), Expect = 5e-35
 Identities = 100/313 (31%), Positives = 161/313 (51%), Gaps = 26/313 (8%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPA 65
           DEL  CVVCGD+A+GYH+NALTCEGCKGFFRR+++K+    C   G+C +    RR C  
Sbjct: 124 DEL--CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQE 181

Query: 66  CRLQKCLDAGMRKDMILS-AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRH 124
           CRL+KC + GM  + +L+  +  + R  K  ++ A QT   ++++ E      + + T+ 
Sbjct: 182 CRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQT---VNEDSEGRDLRQVTSTTKS 238

Query: 125 MGTMFEQFVQFRPPAHLFI---HHQPLPTLAPVLPLVTHFADINTFMVLQ---------V 172
                E     +   H  +   + Q +P       L   F+    F++L          +
Sbjct: 239 CREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVL 298

Query: 173 IKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARV 232
           ++FTK LP F++L  EDQI+LLKG+AVE   +     F  +  +     L   I +    
Sbjct: 299 VEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNS--- 355

Query: 233 GFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEE 292
           G   E++  +F F+ ++ +L++ + EY LL A+ + SP     DR  +  R+ +++LQE 
Sbjct: 356 GISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSP-----DRQYIKDREAVEKLQEP 410

Query: 293 MALTLQSYIKGQQ 305
           +   LQ   K  Q
Sbjct: 411 LLDVLQKLCKIHQ 423


>gi|63054845 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  139 bits (350), Expect = 4e-33
 Identities = 64/138 (46%), Positives = 90/138 (65%), Gaps = 5/138 (3%)

Query: 9   RNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRL 68
           R C VCGD+ATG+HFNA+TCEGCKGFFRR++ +    TCPF G C ++K  RRHC ACRL
Sbjct: 22  RICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRL 81

Query: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----PVQLSKEQEELIRTLLGAHTR 123
           ++C+D GM K+ IL+ E +  +R    +R+ ++        +LS+EQ+ +I  LL AH +
Sbjct: 82  KRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHK 141

Query: 124 HMGTMFEQFVQFRPPAHL 141
                +  F QFRPP  +
Sbjct: 142 TYDPTYSDFCQFRPPVRV 159



 Score =  102 bits (254), Expect = 5e-22
 Identities = 57/156 (36%), Positives = 90/156 (57%), Gaps = 7/156 (4%)

Query: 155 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 214
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 215 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 272
            ++ CG    +Y + D  + G  +E +E L  F   L+KL L E E+VLL A+ + SP  
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSP-- 341

Query: 273 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 308
              DRPGV     I+ +Q+ ++ TLQ+YI+ +   P
Sbjct: 342 ---DRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPP 374


>gi|4507883 vitamin D (1,25-dihydroxyvitamin D3) receptor [Homo
           sapiens]
          Length = 427

 Score =  139 bits (350), Expect = 4e-33
 Identities = 64/138 (46%), Positives = 90/138 (65%), Gaps = 5/138 (3%)

Query: 9   RNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRL 68
           R C VCGD+ATG+HFNA+TCEGCKGFFRR++ +    TCPF G C ++K  RRHC ACRL
Sbjct: 22  RICGVCGDRATGFHFNAMTCEGCKGFFRRSMKRKALFTCPFNGDCRITKDNRRHCQACRL 81

Query: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQT-----PVQLSKEQEELIRTLLGAHTR 123
           ++C+D GM K+ IL+ E +  +R    +R+ ++        +LS+EQ+ +I  LL AH +
Sbjct: 82  KRCVDIGMMKEFILTDEEVQRKREMILKRKEEEALKDSLRPKLSEEQQRIIAILLDAHHK 141

Query: 124 HMGTMFEQFVQFRPPAHL 141
                +  F QFRPP  +
Sbjct: 142 TYDPTYSDFCQFRPPVRV 159



 Score =  102 bits (254), Expect = 5e-22
 Identities = 57/156 (36%), Positives = 90/156 (57%), Gaps = 7/156 (4%)

Query: 155 LPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQT 214
           L ++ H AD+ ++ + +VI F K +P FR L  EDQI LLK +A+E+  +  N +F +  
Sbjct: 224 LSMLPHLADLVSYSIQKVIGFAKMIPGFRDLTSEDQIVLLKSSAIEVIMLRSNESFTMDD 283

Query: 215 QNFLCG--PLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAP 272
            ++ CG    +Y + D  + G  +E +E L  F   L+KL L E E+VLL A+ + SP  
Sbjct: 284 MSWTCGNQDYKYRVSDVTKAGHSLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSP-- 341

Query: 273 YLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRP 308
              DRPGV     I+ +Q+ ++ TLQ+YI+ +   P
Sbjct: 342 ---DRPGVQDAALIEAIQDRLSNTLQTYIRCRHPPP 374


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  135 bits (341), Expect = 4e-32
 Identities = 93/301 (30%), Positives = 151/301 (50%), Gaps = 23/301 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+   +CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 79  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 138

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+ +        +LS + EELI  +  AH        E
Sbjct: 139 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 188

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           +      +   L L   F+++ T  ++++++F K LP F  L I DQ
Sbjct: 189 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 248

Query: 191 ISLLKGAAVEICHIVLNTTFCLQ--TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHG 247
           I+LLK A ++I  + + T +  +  T  F  G  L  T    A  G      +L+F F G
Sbjct: 249 ITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAG 305

Query: 248 TLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRR 307
            L  L++ + E  LL+A+ L        DR  + + +++D+LQE +   L+ Y   ++RR
Sbjct: 306 QLLPLEMDDTETGLLSAICLI-----CGDRMDLEEPEKVDKLQEPLLEALRLY--ARRRR 358

Query: 308 P 308
           P
Sbjct: 359 P 359


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  135 bits (341), Expect = 4e-32
 Identities = 93/301 (30%), Positives = 151/301 (50%), Gaps = 23/301 (7%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+   +CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 90  CFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 149

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+ +        +LS + EELI  +  AH        E
Sbjct: 150 CFEVGMSKEAVRNDRN---KKKKEVKEEGSPDSYELSPQLEELITKVSKAHQ-------E 199

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           +      +   L L   F+++ T  ++++++F K LP F  L I DQ
Sbjct: 200 TFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQ 259

Query: 191 ISLLKGAAVEICHIVLNTTFCLQ--TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHG 247
           I+LLK A ++I  + + T +  +  T  F  G  L  T    A  G      +L+F F G
Sbjct: 260 ITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAG 316

Query: 248 TLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRR 307
            L  L++ + E  LL+A+ L        DR  + + +++D+LQE +   L+ Y   ++RR
Sbjct: 317 QLLPLEMDDTETGLLSAICLI-----CGDRMDLEEPEKVDKLQEPLLEALRLY--ARRRR 369

Query: 308 P 308
           P
Sbjct: 370 P 370


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,586,236
Number of Sequences: 37866
Number of extensions: 614891
Number of successful extensions: 2508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2182
Number of HSP's gapped (non-prelim): 203
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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