Guide to the Human Genome
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Name: HAMP Sequence: fasta or formatted (84aa) NCBI GI: 10863973
Description:

hepcidin antimicrobial peptide preproprotein

Referenced in:

Iron, Copper, and Arsenic Metabolism
Liver
Additional Host Defense Functions

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.5          8           2
 C cysteine           10.7          9           2
 D aspartate           2.4          2           1
 E glutamate           1.2          1           1
 F phenylalanine       4.8          4           1
 G glycine             6.0          5           1
 H histidine           2.4          2           1
 I isoleucine          3.6          3           1
 K lysine              2.4          2           1
 L leucine            13.1         11           7
 M methionine          4.8          4           1
 N asparagine          0.0          0           0
 P proline             4.8          4           1
 Q glutamine           8.3          7           2
 R arginine            9.5          8           5
 S serine              8.3          7           2
 T threonine           4.8          4           1
 V valine              1.2          1           1
 W tryptophan          2.4          2           1
 Y tyrosine            0.0          0           0
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hepcidin antimicrobial peptide preproprotein 
TM4SF1                0.019   transmembrane 4 superfamily member 1 
HIVEP1                0.019   human immunodeficiency virus type I enhancer bindin...
KRTAP5-10             0.013   keratin associated protein 5-10 
LOC100293952          0.013   PREDICTED: hypothetical protein 
LOC100287839          0.013   PREDICTED: hypothetical protein XP_002343254 
MATN1                 0.013   matrilin 1, cartilage matrix protein 
C9orf169              0.013   hypothetical protein LOC375791 
PCDH24                0.006   protocadherin LKC precursor 
LOC100131830          0.006   PREDICTED: hypothetical protein 
SIVA1                 0.006   CD27-binding (Siva) protein isoform 2 
SIVA1                 0.006   CD27-binding (Siva) protein isoform 1 
TM4SF4                0.006   transmembrane 4 superfamily member 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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