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Search of human proteins with 10863913
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10863913 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform A [Homo sapiens]
(973 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10863913 solute carrier family 8 (sodium/calcium exchanger), ... 1939 0.0
gi|163914369 solute carrier family 8 (sodium/calcium exchanger),... 1922 0.0
gi|163914371 solute carrier family 8 (sodium/calcium exchanger),... 1862 0.0
gi|163914373 solute carrier family 8 (sodium/calcium exchanger),... 1808 0.0
gi|15147254 solute carrier family 8 (sodium/calcium exchanger), ... 1325 0.0
gi|33946311 solute carrier family 8 (sodium/calcium exchanger), ... 1315 0.0
gi|33946304 solute carrier family 8 (sodium/calcium exchanger), ... 1313 0.0
gi|17865805 solute carrier family 8 (sodium/calcium exchanger), ... 1312 0.0
gi|57163987 solute carrier family 8 member 2 [Homo sapiens] 1211 0.0
gi|194354001 solute carrier family 8 (sodium/calcium exchanger),... 475 e-134
gi|33946308 solute carrier family 8 (sodium/calcium exchanger), ... 471 e-132
gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens] 87 8e-17
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 75 3e-13
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 75 3e-13
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 75 3e-13
gi|79749430 FRAS1-related extracellular matrix protein 2 precurs... 70 7e-12
gi|108773804 Fraser syndrome 1 [Homo sapiens] 69 2e-11
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e... 68 4e-11
gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sa... 65 2e-10
gi|29788985 solute carrier family 24 member 4 isoform 2 precurso... 65 2e-10
gi|24111228 solute carrier family 24 member 4 isoform 1 precurso... 65 2e-10
gi|45504369 solute carrier family 24, member 5 [Homo sapiens] 64 9e-10
gi|9966787 solute carrier family 24 (sodium/potassium/calcium ex... 59 3e-08
gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens] 51 6e-06
gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens] 51 6e-06
gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens] 51 6e-06
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 51 6e-06
gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens] 45 3e-04
gi|39995086 solute carrier family 24 member 6 [Homo sapiens] 37 0.12
gi|209862785 anoctamin 2 [Homo sapiens] 36 0.15
>gi|10863913 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform A [Homo sapiens]
Length = 973
Score = 1939 bits (5022), Expect = 0.0
Identities = 973/973 (100%), Positives = 973/973 (100%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV
Sbjct: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
Query: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 720
FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY
Sbjct: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 720
Query: 721 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 780
EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF
Sbjct: 721 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 780
Query: 781 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 840
LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF
Sbjct: 781 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 840
Query: 841 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 900
VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF
Sbjct: 841 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 900
Query: 901 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 960
KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF
Sbjct: 901 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 960
Query: 961 FSSLEAYCHIKGF 973
FSSLEAYCHIKGF
Sbjct: 961 FSSLEAYCHIKGF 973
>gi|163914369 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform B [Homo sapiens]
Length = 968
Score = 1922 bits (4978), Expect = 0.0
Identities = 968/973 (99%), Positives = 968/973 (99%), Gaps = 5/973 (0%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTIT GQPV
Sbjct: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTIT-----GQPV 655
Query: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 720
FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY
Sbjct: 656 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 715
Query: 721 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 780
EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF
Sbjct: 716 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 775
Query: 781 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 840
LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF
Sbjct: 776 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 835
Query: 841 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 900
VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF
Sbjct: 836 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 895
Query: 901 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 960
KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF
Sbjct: 896 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 955
Query: 961 FSSLEAYCHIKGF 973
FSSLEAYCHIKGF
Sbjct: 956 FSSLEAYCHIKGF 968
>gi|163914371 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform C [Homo sapiens]
Length = 960
Score = 1862 bits (4822), Expect = 0.0
Identities = 939/973 (96%), Positives = 947/973 (97%), Gaps = 13/973 (1%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
EIVK I++++ D EEYEK +F L + EP+ + K GGFTIT GQPV
Sbjct: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMK--------GGFTIT-----GQPV 647
Query: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 720
FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY
Sbjct: 648 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 707
Query: 721 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 780
EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF
Sbjct: 708 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 767
Query: 781 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 840
LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF
Sbjct: 768 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 827
Query: 841 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 900
VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF
Sbjct: 828 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 887
Query: 901 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 960
KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF
Sbjct: 888 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 947
Query: 961 FSSLEAYCHIKGF 973
FSSLEAYCHIKGF
Sbjct: 948 FSSLEAYCHIKGF 960
>gi|163914373 solute carrier family 8 (sodium/calcium exchanger),
member 1 isoform D [Homo sapiens]
Length = 937
Score = 1808 bits (4682), Expect = 0.0
Identities = 916/973 (94%), Positives = 924/973 (94%), Gaps = 36/973 (3%)
Query: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI
Sbjct: 1 MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVI 60
Query: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG
Sbjct: 61 LPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNG 120
Query: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF
Sbjct: 121 ETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMF 180
Query: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF
Sbjct: 181 IIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFF 240
Query: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV
Sbjct: 241 FFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHV 300
Query: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS
Sbjct: 301 ENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKS 360
Query: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE
Sbjct: 361 RAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLE 420
Query: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII
Sbjct: 421 NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGII 480
Query: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF
Sbjct: 481 DDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIF 540
Query: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND
Sbjct: 541 TFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
Query: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
EIVK I++++ D EEYEK +F L + EP+ + K GGFTIT
Sbjct: 601 EIVKIITIRIFDREEYEKECSFSLVLEEPKWIRRGMK--------GGFTIT--------- 643
Query: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 720
DEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY
Sbjct: 644 -------------------DEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESY 684
Query: 721 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 780
EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF
Sbjct: 685 EFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHF 744
Query: 781 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 840
LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF
Sbjct: 745 LTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVF 804
Query: 841 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 900
VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF
Sbjct: 805 VALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQF 864
Query: 901 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 960
KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF
Sbjct: 865 KVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIF 924
Query: 961 FSSLEAYCHIKGF 973
FSSLEAYCHIKGF
Sbjct: 925 FSSLEAYCHIKGF 937
>gi|15147254 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform A precursor [Homo sapiens]
Length = 925
Score = 1325 bits (3429), Expect = 0.0
Identities = 680/978 (69%), Positives = 790/978 (80%), Gaps = 61/978 (6%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS---TLACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYL 655
EF+NDE VKTI +KVIDDE YEKNK +F+E+ PR+V+MS +KALLL+
Sbjct: 588 EFKNDETVKTIHIKVIDDEAYEKNKNYFIEMMGPRMVDMSFQKALLLS------------ 635
Query: 656 FGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVI 715
+ LT +EEE +RIAEMG+P+LGEH KLEVI
Sbjct: 636 ----------------------------PDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVI 667
Query: 716 IEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFD 775
IEESYEFK+TVDKLIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFD
Sbjct: 668 IEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFD 727
Query: 776 YVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSV 835
YVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSV
Sbjct: 728 YVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSV 787
Query: 836 TAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAA 895
TAVVFVA GTSVPDTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A
Sbjct: 788 TAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAL 847
Query: 896 NGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLW 955
G++F VS GTLAFSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LW
Sbjct: 848 QGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 907
Query: 956 LLYIFFSSLEAYCHIKGF 973
LLYI F++LEAYC+IKGF
Sbjct: 908 LLYILFATLEAYCYIKGF 925
>gi|33946311 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform C precursor [Homo sapiens]
Length = 927
Score = 1315 bits (3403), Expect = 0.0
Identities = 674/978 (68%), Positives = 787/978 (80%), Gaps = 59/978 (6%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS---TLACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYL 655
EF+NDE VKTI VK++D+EEYE+ + FF+ +GEP+ +E
Sbjct: 588 EFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERG-------------------- 627
Query: 656 FGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVI 715
+S ++ D D K LT +EEE +RIAEMG+P+LGEH KLEVI
Sbjct: 628 ----------------ISALLLSPDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVI 669
Query: 716 IEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFD 775
IEESYEFK+TVDKLIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFD
Sbjct: 670 IEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFD 729
Query: 776 YVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSV 835
YVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSV
Sbjct: 730 YVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSV 789
Query: 836 TAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAA 895
TAVVFVA GTSVPDTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A
Sbjct: 790 TAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAL 849
Query: 896 NGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLW 955
G++F VS GTLAFSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LW
Sbjct: 850 QGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 909
Query: 956 LLYIFFSSLEAYCHIKGF 973
LLYI F++LEAYC+IKGF
Sbjct: 910 LLYILFATLEAYCYIKGF 927
>gi|33946304 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform D precursor [Homo sapiens]
Length = 921
Score = 1313 bits (3397), Expect = 0.0
Identities = 674/978 (68%), Positives = 785/978 (80%), Gaps = 65/978 (6%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS---TLACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYL 655
EF+NDE VKTI VK++D+EEYE+ + FF+ +GEP+ +E
Sbjct: 588 EFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERG-------------------- 627
Query: 656 FGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVI 715
I+D D K LT +EEE +RIAEMG+P+LGEH KLEVI
Sbjct: 628 ----------------------ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVI 663
Query: 716 IEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFD 775
IEESYEFK+TVDKLIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFD
Sbjct: 664 IEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFD 723
Query: 776 YVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSV 835
YVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSV
Sbjct: 724 YVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSV 783
Query: 836 TAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAA 895
TAVVFVA GTSVPDTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A
Sbjct: 784 TAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAL 843
Query: 896 NGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLW 955
G++F VS GTLAFSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LW
Sbjct: 844 QGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 903
Query: 956 LLYIFFSSLEAYCHIKGF 973
LLYI F++LEAYC+IKGF
Sbjct: 904 LLYILFATLEAYCYIKGF 921
>gi|17865805 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform B precursor [Homo sapiens]
Length = 924
Score = 1312 bits (3396), Expect = 0.0
Identities = 672/978 (68%), Positives = 783/978 (80%), Gaps = 62/978 (6%)
Query: 4 MRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGE----CTGSYYCKKGV 59
M L L P S H + +LF ++ + AE G+ TG+ C+GS CK+GV
Sbjct: 1 MAWLRLQPLTSAFLHFGLVTFVLF--LNGLRAEAGGSGDVPSTGQNNESCSGSSDCKEGV 58
Query: 60 ILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPN 119
ILPIW P++PS GDKIAR VYFVA++YMFLGVSIIADRFM+SIEVITSQE+E+TIKKPN
Sbjct: 59 ILPIWYPENPSLGDKIARVIVYFVALIYMFLGVSIIADRFMASIEVITSQEREVTIKKPN 118
Query: 120 GETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNM 179
GET+ TT+R+WNETVSNLTLMALGSSAPEILLS+IEVCGH F AGDLGPSTIVGSAAFNM
Sbjct: 119 GETSTTTIRVWNETVSNLTLMALGSSAPEILLSLIEVCGHGFIAGDLGPSTIVGSAAFNM 178
Query: 180 FIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTF 239
FIII +CVYV+PDGETRKIKHLRVFF+TAAWSIFAY WLY+IL+V SPGVV+VWEGLLT
Sbjct: 179 FIIIGICVYVIPDGETRKIKHLRVFFITAAWSIFAYIWLYMILAVFSPGVVQVWEGLLTL 238
Query: 240 FFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSH 299
FFFP+CV+ AWVAD+RLLFYKY++K+YR K RG+IIE EGD P IEMDGK++NSH
Sbjct: 239 FFFPVCVLLAWVADKRLLFYKYMHKKYRTDKHRGIIIETEGDHPKG---IEMDGKMMNSH 295
Query: 300 VENFLDGALV-LEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQ 358
FLDG LV LE E D E+RREM RILK+LKQKHP+K+++QL+E+ANY LS QQ
Sbjct: 296 ---FLDGNLVPLEGKEVD----ESRREMIRILKDLKQKHPEKDLDQLVEMANYYALSHQQ 348
Query: 359 KSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQC 418
KSRAFYRIQATR+MTGAGNILK+HAA+QA+KA SM EV+T+ E D +SK+FF+ +YQC
Sbjct: 349 KSRAFYRIQATRMMTGAGNILKKHAAEQAKKASSMSEVHTDEPE-DFISKVFFDPCSYQC 407
Query: 419 LENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVG 478
LENCG V LT++R+GGD++ T++VD++TEDG+ANAG+DYEFTEGTVV KPG+TQKE VG
Sbjct: 408 LENCGAVLLTVVRKGGDMSKTMYVDYKTEDGSANAGADYEFTEGTVVLKPGETQKEFSVG 467
Query: 479 IIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS---TLACLGSPSTATVTIFDDD 535
IIDDDIFEEDE+F V LSNV++ E E+G+ A S A L SP ATVTI DDD
Sbjct: 468 IIDDDIFEEDEHFFVRLSNVRIEEEQPEEGMPPAIFNSLPLPRAVLASPCVATVTILDDD 527
Query: 536 HAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGEL 595
HAGIFTFE HVSESIG+MEVKVLRTSGARG VIVP++T+EGTA+GGGEDFEDT GEL
Sbjct: 528 HAGIFTFECDTIHVSESIGVMEVKVLRTSGARGTVIVPFRTVEGTAKGGGEDFEDTYGEL 587
Query: 596 EFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYL 655
EF+NDE VKTI VK++D+EEYE+ + FF+ +GEP+ +E LL
Sbjct: 588 EFKNDETVKTIRVKIVDEEEYERQENFFIALGEPKWMERGISALLL-------------- 633
Query: 656 FGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVI 715
+ LT +EEE +RIAEMG+P+LGEH KLEVI
Sbjct: 634 ---------------------------SPDRKLTMEEEEAKRIAEMGKPVLGEHPKLEVI 666
Query: 716 IEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFD 775
IEESYEFK+TVDKLIKKTNLALVVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFD
Sbjct: 667 IEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFD 726
Query: 776 YVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSV 835
YVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSV
Sbjct: 727 YVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSV 786
Query: 836 TAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAA 895
TAVVFVA GTSVPDTFASK AA QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A
Sbjct: 787 TAVVFVAFGTSVPDTFASKAAALQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWAL 846
Query: 896 NGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLW 955
G++F VS GTLAFSVTLFTIFAF+ + VLLYRRRP +GGELGGPR KL T+ LFV LW
Sbjct: 847 QGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLW 906
Query: 956 LLYIFFSSLEAYCHIKGF 973
LLYI F++LEAYC+IKGF
Sbjct: 907 LLYILFATLEAYCYIKGF 924
>gi|57163987 solute carrier family 8 member 2 [Homo sapiens]
Length = 921
Score = 1211 bits (3132), Expect = 0.0
Identities = 612/930 (65%), Positives = 734/930 (78%), Gaps = 50/930 (5%)
Query: 46 TGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEV 105
TG C GSY C+ GV+LP+WEP DPS GDK ARA VYFVAMVYMFLGVSIIADRFM++IEV
Sbjct: 40 TGGCQGSYRCQPGVLLPVWEPDDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMAAIEV 99
Query: 106 ITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGD 165
ITS+EKEITI K NGET+ TVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNF AG+
Sbjct: 100 ITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGE 159
Query: 166 LGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVI 225
LGP TIVGSAAFNMF++IA+C+YV+P GE+RKIKHLRVFFVTA+WSIFAY WLY+IL+V
Sbjct: 160 LGPGTIVGSAAFNMFVVIAVCIYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVF 219
Query: 226 SPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSS 285
SPGVV+VWE LLT FFP+CVVFAW+AD+RLLFYKYVYKRYR + G+II EGD P S
Sbjct: 220 SPGVVQVWEALLTLVFFPVCVVFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKS 279
Query: 286 KTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQL 345
IE+DG V + L G + R+ D +RRE+ +ILK+LKQKHPDK++EQL
Sbjct: 280 ---IELDGTFVGAEAPGELGGLGPGPAEARELD--ASRREVIQILKDLKQKHPDKDLEQL 334
Query: 346 IELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDP 405
+ +ANY L QQKSRAFYRIQATRLMTGAGN+L+RHAAD +R+A + E+D
Sbjct: 335 VGIANYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADASRRAAPAEGAGED--EDDG 392
Query: 406 VSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVV 465
S+IFFE Y CLENCG+V L++ +GG+ +T +VD+RTEDG+A AGSDYE++EGT+V
Sbjct: 393 ASRIFFEPSLYHCLENCGSVLLSVTCQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLV 452
Query: 466 FKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVS-TLACLGSP 524
FKPG+TQKE+R+GIIDDDIFEEDE+F V L N++V G+ E + L +P
Sbjct: 453 FKPGETQKELRIGIIDDDIFEEDEHFFVRLLNLRV---GDAQGMFEPDGGGRPKGRLVAP 509
Query: 525 STATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG 584
ATVTI DDDHAGIF+F++ + HVSE +G ++V+V+R+SGARG V +PY+T++GTARGG
Sbjct: 510 LLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGG 569
Query: 585 GEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNE 644
G +ED CGELEF +DE +KT+ VK++DDEEYEK FF+E+G+P+ ++ ALLLN
Sbjct: 570 GVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKRG-ISALLLN- 627
Query: 645 LGGFTITGKYLFGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRP 704
+ D + LT++EEE RRIAEMG+P
Sbjct: 628 ------------------------------------QGDGDRKLTAEEEEARRIAEMGKP 651
Query: 705 ILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAG-EDDDDD 763
+LGE+ +LEVIIEESY+FK+TVDKLIKKTNLALV+GT+SWREQF+EAITVSAG E++++D
Sbjct: 652 VLGENCRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITVSAGDEEEEED 711
Query: 764 ECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLAS 823
EE+LPSCFDYVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+IGLLTA IGDLAS
Sbjct: 712 GSREERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFGVSILVIGLLTALIGDLAS 771
Query: 824 HFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIG 883
HFGCT+GLKDSV AVVFVALGTS+PDTFASKVAA QDQ ADASIGNVTGSNAVNVFLG+G
Sbjct: 772 HFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLG 831
Query: 884 VAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTA 943
VAWS+AA+Y A G F+V GTLAFSVTLFT+FAF+ + VLLYRRRP IGGELGGPR
Sbjct: 832 VAWSVAAVYWAVQGRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGP 891
Query: 944 KLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 973
KL T+ LF+ LWLLYI F+SLEAYCHI+GF
Sbjct: 892 KLATTALFLGLWLLYILFASLEAYCHIRGF 921
>gi|194354001 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform G [Homo sapiens]
Length = 298
Score = 475 bits (1223), Expect = e-134
Identities = 237/296 (80%), Positives = 263/296 (88%), Gaps = 2/296 (0%)
Query: 678 IADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLAL 737
I+D D K LT +EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLAL
Sbjct: 5 ISDVTDRK--LTMEEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLAL 62
Query: 738 VVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEY 797
VVGT+SWR+QF+EAITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY
Sbjct: 63 VVGTHSWRDQFMEAITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEY 122
Query: 798 WNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAA 857
+GWACF VSIL+IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA
Sbjct: 123 CHGWACFAVSILIIGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAA 182
Query: 858 TQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIF 917
QD YADASIGNVTGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLAFSVTLFTIF
Sbjct: 183 LQDVYADASIGNVTGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIF 242
Query: 918 AFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 973
AF+ + VLLYRRRP +GGELGGPR KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 243 AFVCISVLLYRRRPHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 298
>gi|33946308 solute carrier family 8 (sodium/calcium exchanger),
member 3 isoform F [Homo sapiens]
Length = 284
Score = 471 bits (1212), Expect = e-132
Identities = 231/283 (81%), Positives = 256/283 (90%)
Query: 691 KEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIE 750
+EEE +RIAEMG+P+LGEH KLEVIIEESYEFK+TVDKLIKKTNLALVVGT+SWR+QF+E
Sbjct: 2 EEEEAKRIAEMGKPVLGEHPKLEVIIEESYEFKTTVDKLIKKTNLALVVGTHSWRDQFME 61
Query: 751 AITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILM 810
AITVSA D+D+DE GEE+LPSCFDYVMHFLTVFWKVLFA VPPTEY +GWACF VSIL+
Sbjct: 62 AITVSAAGDEDEDESGEERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFAVSILI 121
Query: 811 IGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNV 870
IG+LTA IGDLASHFGCTIGLKDSVTAVVFVA GTSVPDTFASK AA QD YADASIGNV
Sbjct: 122 IGMLTAIIGDLASHFGCTIGLKDSVTAVVFVAFGTSVPDTFASKAAALQDVYADASIGNV 181
Query: 871 TGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRR 930
TGSNAVNVFLGIG+AWS+AAIY A G++F VS GTLAFSVTLFTIFAF+ + VLLYRRR
Sbjct: 182 TGSNAVNVFLGIGLAWSVAAIYWALQGQEFHVSAGTLAFSVTLFTIFAFVCISVLLYRRR 241
Query: 931 PEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF 973
P +GGELGGPR KL T+ LFV LWLLYI F++LEAYC+IKGF
Sbjct: 242 PHLGGELGGPRGCKLATTWLFVSLWLLYILFATLEAYCYIKGF 284
>gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]
Length = 6306
Score = 87.0 bits (214), Expect = 8e-17
Identities = 71/270 (26%), Positives = 122/270 (45%), Gaps = 22/270 (8%)
Query: 398 TEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDY 457
T V + P + F + E V +TIIR GD + V + ++T GTA AG D+
Sbjct: 4258 TVVASDSPYGRFAFSHEQLRVSE-AQRVNITIIRSSGDFGH-VRLWYKTMSGTAEAGLDF 4315
Query: 458 EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEAN-HVS 516
G ++F+ G+ +K + V I+DDD E E F + ++ V++ + I E +
Sbjct: 4316 VPAAGELLFEAGEMRKSLHVEILDDDYPEGPEEFSLTITKVELQGRGYDFTIQENGLQID 4375
Query: 517 TLACLGSPSTATVTIFDDDHA-GIFTFEEPVT--HVSESIGIMEVKVLRTSGARGNVIVP 573
+G+ S + I +D+A GI F+ T V E +G++ + V+R G G V
Sbjct: 4376 QPPEIGNISIVRIIIMKNDNAEGIIEFDPKYTAFEVEEDVGLIMIPVVRLHGTYGYVTAD 4435
Query: 574 YKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVE 633
+ + +A GG D+ + FQ+ + + I++ +IDD E E
Sbjct: 4436 FISQSSSASPGGVDYILHGSTVTFQHGQNLSFINISIIDDNE----------------SE 4479
Query: 634 MSEKKALLLNELGGFTITGKYLFGQPVFRK 663
E +LL G + G++L + + K
Sbjct: 4480 FEEPIEILLTGATGGAVLGRHLVSRIIIAK 4509
Score = 77.0 bits (188), Expect = 8e-14
Identities = 67/223 (30%), Positives = 103/223 (46%), Gaps = 21/223 (9%)
Query: 420 ENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGI 479
E G + L +IR G L V +FRT TA + DY+ GT+ F+PG+ K I + I
Sbjct: 1734 EEDGEIRLLVIRAQG-LLGRVTAEFRTVSLTAFSPEDYQNVAGTLEFQPGERYKYIFINI 1792
Query: 480 IDDDIFEEDENFLVHLSNV--------KVSSEASEDGILE--ANHVSTLACLGSPSTATV 529
D+ I E +++F V L N+ +V S DG +E + A LG S V
Sbjct: 1793 TDNSIPELEKSFKVELLNLEGGVAELFRVDGSGSGDGDMEFFLPTIHKRASLGVASQILV 1852
Query: 530 TIFDDDHA-GIFTFEEPVTHVS-----ESIGIMEVKVLRTSGARGNVIVPYKTIEGTARG 583
TI DHA G+F F VS + + + V+R G V + + I+ G
Sbjct: 1853 TIAASDHAHGVFEFSPESLFVSGTEPEDGYSTVTLNVIRHHGTLSPVTLHW-NIDSDPDG 1911
Query: 584 GGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
D T G + F+ + I+V+++ DE+ E +K F + +
Sbjct: 1912 ---DLAFTSGNITFEIGQTSANITVEILPDEDPELDKAFSVSV 1951
Score = 73.9 bits (180), Expect = 7e-13
Identities = 65/223 (29%), Positives = 96/223 (43%), Gaps = 27/223 (12%)
Query: 410 FFEQGTYQCLENCGTVALTIIRRGGDLTN-TVFVDFRTEDGTANAGSDYEFTEGTVVFKP 468
F Q + E TV II R G+ N T V ED D+ T
Sbjct: 35 FTGQTEFVVNETSTTVIRLIIERIGEPANVTAIVSLYGEDA-----GDFFDTYAAAFIPA 89
Query: 469 GDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTAT 528
G+T + + + + DDD+ E DE F+ HL+ K S+ LG P T T
Sbjct: 90 GETNRTVYIAVCDDDLPEPDETFIFHLTLQKPSANVK---------------LGWPRTVT 134
Query: 529 VTIFDDDHA-GIFTFEE-PVTHVSESIG---IMEVKVLRTSGARGNVIVPYKTIEGTARG 583
VTI +D+A GI +F P VSE G M + ++R G G V+V ++ +EG
Sbjct: 135 VTILSNDNAFGIISFNMLPSIAVSEPKGRNESMPLTLIREKGTYGMVMVTFE-VEGGPNP 193
Query: 584 GGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
ED G + F ++ V+DDE E ++ F +++
Sbjct: 194 PDEDLSPVKGNITFPPGRATVIYNLTVLDDEVPENDEIFLIQL 236
Score = 72.0 bits (175), Expect = 3e-12
Identities = 65/230 (28%), Positives = 103/230 (44%), Gaps = 40/230 (17%)
Query: 420 ENCGTVALTIIRRGGDLTNTVFVDFRTE-------DGTANAGSDYEFTEGTVVFKPGDTQ 472
EN T+ L I R G L + + R + D A DY E ++ K +
Sbjct: 3793 ENTTTLQLQIARDKG-LLGDIAIHLRAQPNFLLHVDNQATENEDYVLQETIIIMKENIKE 3851
Query: 473 KEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPST------ 526
V I+ DD+ E +E F+V ++ E N V++ G PS
Sbjct: 3852 AHAEVSILPDDLPELEEGFIVTIT--------------EVNLVNSDFSTGQPSVRRPGME 3897
Query: 527 -ATVTIFD-DDHAGIFTFE------EPVT--HVSESIGIMEVKVLRTSGARGNVIVPYKT 576
A + I + DD GIF F E +T V + +++V V+R +G+ G V V +K
Sbjct: 3898 IAEIMIEENDDPRGIFMFHVTRGAGEVITAYEVPPPLNVLQVPVVRLAGSFGAVNVYWKA 3957
Query: 577 IEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
+A G EDF+ + G LEF + ++ I + +IDD E+E +TF + +
Sbjct: 3958 SPDSA--GLEDFKPSHGILEFADKQVTAMIEITIIDDAEFELTETFNISL 4005
Score = 71.6 bits (174), Expect = 3e-12
Identities = 62/232 (26%), Positives = 106/232 (45%), Gaps = 38/232 (16%)
Query: 424 TVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDD 483
TV L +IR G L+ V + + + ++ D FT G + F+ G T I V I+ D+
Sbjct: 1884 TVTLNVIRHHGTLS-PVTLHWNID---SDPDGDLAFTSGNITFEIGQTSANITVEILPDE 1939
Query: 484 IFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIF-DDDHAGIFTF 542
E D+ F V + +V S LG+ AT+T+ DD GIF F
Sbjct: 1940 DPELDKAFSVSVLSVSSGS------------------LGAHINATLTVLASDDPYGIFIF 1981
Query: 543 EE---PVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG-----------GEDF 588
E PV V E+ + + ++R G G V+V Y T++ + G D+
Sbjct: 1982 SEKNRPVK-VEEATQNITLSIIRLKGLMGKVLVSYATLDDMEKPPYFPPNLARATQGRDY 2040
Query: 589 EDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKAL 640
G F ++ TI++ ++DD+E E++++ F+E+ LV + +++
Sbjct: 2041 IPASGFALFGANQSEATIAISILDDDEPERSESVFIELLNSTLVAKVQSRSI 2092
Score = 70.9 bits (172), Expect = 6e-12
Identities = 70/245 (28%), Positives = 106/245 (43%), Gaps = 38/245 (15%)
Query: 449 GTANAGSDYE-FTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFL-----VHLSNVKVSS 502
G A AGSDYE T + + GD + V I+ DD E DE+FL VHL N+ S
Sbjct: 2495 GQAVAGSDYEPVTRQWAIMQEGDEFANLTVSILPDDFPEMDESFLISLLEVHLMNISAS- 2553
Query: 503 EASEDGILEANHVSTLACLGSPSTATVTI-FDDDHAGIFTFEEPVTHVSES--------- 552
+ +G P+ +TV I + D G+F + SE
Sbjct: 2554 ------------LKNQPTIGQPNISTVVIALNGDAFGVFVIYNISPNTSEDGLFVEVQEQ 2601
Query: 553 -IGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVI 611
++E+ + RT G+ G V V ++ + GTA G DF L F E KT+ + ++
Sbjct: 2602 PQTLVELMIHRTGGSLGQVAVEWRVVGGTAT-EGLDFIGAGEILTFAEGETKKTVILTIL 2660
Query: 612 DDEEYEKNKTFFLEI----GEPRLVEMSEKKALLLNELGGFTITGKYLFGQPVFRKVHAR 667
DD E E +++ + + G R++ S+ + +N L + G F Q R V
Sbjct: 2661 DDSEPEDDESIIVSLVYTEGGSRILPSSD--TVRVNILANDNVAGIVSF-QTASRSVIGH 2717
Query: 668 EHPIL 672
E IL
Sbjct: 2718 EGEIL 2722
Score = 69.3 bits (168), Expect = 2e-11
Identities = 79/297 (26%), Positives = 123/297 (41%), Gaps = 42/297 (14%)
Query: 398 TEVTENDPVSKIFFEQGT--YQCLENCGTVALTIIRRGGDLTNTVFVDFRTED------- 448
T + +DP F + + E + L+IIR G L V V + T D
Sbjct: 1968 TVLASDDPYGIFIFSEKNRPVKVEEATQNITLSIIRLKG-LMGKVLVSYATLDDMEKPPY 2026
Query: 449 -----GTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSN----VK 499
A G DY G +F ++ I + I+DDD E E+ + L N K
Sbjct: 2027 FPPNLARATQGRDYIPASGFALFGANQSEATIAISILDDDEPERSESVFIELLNSTLVAK 2086
Query: 500 VSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVK 559
V S + + V T+A L + I +DD G P+ V+E+ +
Sbjct: 2087 VQSRSIPNSPRLGPKVETIAQL-------IIIANDDAFGTLQLSAPIVRVAENHVGPIIN 2139
Query: 560 VLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKN 619
V RT GA +V V +K + TA GED+ ++ E K + + VI+D E
Sbjct: 2140 VTRTGGAFADVSVKFKAVPITAI-AGEDYSIASSDVVLLEGETSKAVPIYVINDIYPELE 2198
Query: 620 KTFFLEI-----GEPRLVEMSEKKALLLNE-------LGGFTITGKYLFGQPVFRKV 664
++F +++ G RL ++E A+++ E L GF IT K + +P F V
Sbjct: 2199 ESFLVQLMNETTGGARLGALTE--AVIIIEASDDPYGLFGFQIT-KLIVEEPEFNSV 2252
Score = 65.9 bits (159), Expect = 2e-10
Identities = 60/200 (30%), Positives = 92/200 (46%), Gaps = 22/200 (11%)
Query: 425 VALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDI 484
V L I R GG L V V++R GTA G D+ + F G+T+K + + I+DD
Sbjct: 2606 VELMIHRTGGSL-GQVAVEWRVVGGTATEGLDFIGAGEILTFAEGETKKTVILTILDDSE 2664
Query: 485 FEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDH-AGIFTFE 543
E+DE+ +V L + S L S T V I +D+ AGI +F+
Sbjct: 2665 PEDDESIIVSLVYTEGGSR----------------ILPSSDTVRVNILANDNVAGIVSFQ 2708
Query: 544 EPVTHVSESIG-IMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEI 602
V G I++ V+RT RGNV V +K I + +F + G+L F +
Sbjct: 2709 TASRSVIGHEGEILQFHVIRTFPGRGNVTVNWKII---GQNLELNFANFSGQLFFPEGSL 2765
Query: 603 VKTISVKVIDDEEYEKNKTF 622
T+ V ++DD E+ + +
Sbjct: 2766 NTTLFVHLLDDNIPEEKEVY 2785
Score = 64.7 bits (156), Expect = 4e-10
Identities = 60/228 (26%), Positives = 94/228 (41%), Gaps = 27/228 (11%)
Query: 420 ENCGTVALTIIRRGG--DLTNTVFVDFRTE-DGTANAGSDYEFTEGTVVFKPGDTQKEIR 476
E T++ + R G D + + + E DG D+ GT+ F P + +
Sbjct: 1587 EEGSTISCVVERTRGALDYVHVFYTISQIETDGINYLVDDFANASGTITFLPWQRSEVLN 1646
Query: 477 VGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDH 536
+ ++DDDI E +E F V + S DG L + S + T +TI DH
Sbjct: 1647 IYVLDDDIPELNEYF-----RVTLVSAIPGDGKLGSTPTSGASIDPEKETTDITIKASDH 1701
Query: 537 A-GIFTFEE-----------------PVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIE 578
G+ F P V E G + + V+R G G V ++T+
Sbjct: 1702 PYGLLQFSTGLPPQPKDAMTLPASSVPHITVEEEDGEIRLLVIRAQGLLGRVTAEFRTVS 1761
Query: 579 GTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
TA ED+++ G LEFQ E K I + + D+ E K+F +E+
Sbjct: 1762 LTA-FSPEDYQNVAGTLEFQPGERYKYIFINITDNSIPELEKSFKVEL 1808
Score = 63.9 bits (154), Expect = 7e-10
Identities = 68/248 (27%), Positives = 106/248 (42%), Gaps = 37/248 (14%)
Query: 427 LTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFE 486
+ + R GG + V V F+ TA AG DY VV G+T K + + +I+D E
Sbjct: 2138 INVTRTGGAFAD-VSVKFKAVPITAIAGEDYSIASSDVVLLEGETSKAVPIYVINDIYPE 2196
Query: 487 EDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTI-FDDDHAGIFTFEEP 545
+E+FLV L N A LG+ + A + I DD G+F F+
Sbjct: 2197 LEESFLVQLMNETTGG----------------ARLGALTEAVIIIEASDDPYGLFGFQIT 2240
Query: 546 VTHVSE----SIGIMEVKVLRTSGARGNVIVPY-KTIEGTARGGGEDFEDTCGELEFQND 600
V E S+ + + ++R SG GNV V + TI G G D G + F
Sbjct: 2241 KLIVEEPEFNSVKV-NLPIIRNSGTLGNVTVQWVATINGQLATG--DLRVVSGNVTFAPG 2297
Query: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTIT------GKY 654
E ++T+ ++V+ D+ E E+ + +L + S + L+ + I G
Sbjct: 2298 ETIQTLLLEVLADDVPE-----IEEVIQVQLTDASGGGTIGLDRIANIIIPANDDPYGTV 2352
Query: 655 LFGQPVFR 662
F Q V+R
Sbjct: 2353 AFAQMVYR 2360
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 23/209 (11%)
Query: 423 GTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS-DYEFTE--GTVVFKPGDTQKEIRVGI 479
G A + R G + T V + T+DG A A D+ E T++F+ G Q+ I + +
Sbjct: 1017 GETANFTVLRNGSVDVTCMVQYATKDGKATARERDFIPVEKGETLIFEVGSRQQSISIFV 1076
Query: 480 IDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTI-FDDDHAG 538
+D I E DE F + L N + + G+ ATV I +DD G
Sbjct: 1077 NEDGIPETDEPFYIILLNSTGDTVVYQYGV-----------------ATVIIEANDDPNG 1119
Query: 539 IFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEG-TARGGGEDFEDTCGELEF 597
IF+ EP+ E +LR G G+V V ++ + +A G++F +T G + F
Sbjct: 1120 IFSL-EPIDKAVEEGKTNAFWILRHRGYFGSVSVSWQLFQNDSALQPGQEFYETSGTVNF 1178
Query: 598 QNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
+ E K I + D+ E N+ +FL++
Sbjct: 1179 MDGEEAKPIILHAFPDKIPEFNEFYFLKL 1207
Score = 60.8 bits (146), Expect = 6e-09
Identities = 52/221 (23%), Positives = 93/221 (42%), Gaps = 8/221 (3%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKP 468
I ++Q ++ E G++ L + +R + V + ++ A G DY FT + F
Sbjct: 2962 IEWQQSRFEVNETHGSLTL-VAQRSREPLGHVSLFVYAQNLEAQVGLDYIFTPMILHFAD 3020
Query: 469 GDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTAT 528
G+ K + + I+DDDI E DE F + L+N E L N ++ + L +
Sbjct: 3021 GERYKNVNIMILDDDIPEGDEKFQLILTNPSPGLE------LGKNTIALIIVLANDDGPG 3074
Query: 529 VTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDF 588
V F++ F E +V ES+ ++ + G G V V + E + +D
Sbjct: 3075 VLSFNNSE-HFFLREPTALYVQESVAVLYIVREPAQGLFGTVTVQFIVTEVNSSNESKDL 3133
Query: 589 EDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP 629
+ G + + K + + I D E E ++ F + P
Sbjct: 3134 TPSKGYIVLEEGVRFKALQISAILDTEPEMDEYFVCTLFNP 3174
Score = 58.5 bits (140), Expect = 3e-08
Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 27/164 (16%)
Query: 455 SDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANH 514
SD+ + G ++F+PG+ + I V I+DD + E++E+F V L N K +E
Sbjct: 3585 SDFIPSSGELIFEPGEREATIAVNILDDTVPEKEESFKVQLKNPKGGAE----------- 3633
Query: 515 VSTLACLGSPSTATVTIFDDDHA-GIFTFEEPVTHVS----ESIGIMEVKVLRTSGARGN 569
+G + T+TI +D A GI F + + E ++ + V R G G
Sbjct: 3634 ------IGINDSVTITILSNDDAYGIVAFAQNSLYKQVEEMEQDSLVTLNVERLKGTYGR 3687
Query: 570 VIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDD 613
+ TI A G D T G + F +++ TI++ ++ D
Sbjct: 3688 I-----TIAWEADGSISDIFPTSGVILFTEGQVLSTITLTILAD 3726
Score = 51.2 bits (121), Expect = 5e-06
Identities = 62/257 (24%), Positives = 105/257 (40%), Gaps = 39/257 (15%)
Query: 392 SMHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVD-------- 443
S + + + +ND S + F Q Y E + + ++R + N + D
Sbjct: 248 SRNSIEIIIKKND--SPVRFLQSIYLVPEEDHILIIPVVRGKDNNGNLIGSDEYEVSISY 305
Query: 444 -FRTEDGTANAGSDYEFTE----GTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNV 498
T + TA+A + +F + TVVF P + ++ I+DD I E E+F + L
Sbjct: 306 AVTTGNSTAHAQQNLDFIDLQPNTTVVFPPFIHESHLKFQIVDDTIPEIAESFHIMLLKD 365
Query: 499 KVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHA-GIFT-----FEEPVTHVSES 552
+ + A L SPS VTI +D G+ + FE V +
Sbjct: 366 TLQGD---------------AVLISPSVVQVTIKPNDKPYGVLSFNSVLFERTVIIDEDR 410
Query: 553 IG-IMEVKVLRTSGARGNVIVPYKTIEGTARGG--GEDFEDTCGELEFQNDEIVKTISVK 609
I E+ V+R G GNV + + D + G L F +++ TI +
Sbjct: 411 ISRYEEITVVRNGGTHGNVSANWVLTRNSTDPSPVTADIRPSSGVLHFAQGQMLATIPLT 470
Query: 610 VIDDEEYEKNKTFFLEI 626
V+DD+ E+ + + L+I
Sbjct: 471 VVDDDLPEEAEAYLLQI 487
Score = 50.1 bits (118), Expect = 1e-05
Identities = 60/255 (23%), Positives = 102/255 (40%), Gaps = 39/255 (15%)
Query: 400 VTENDPVSKIFFEQGT---------YQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGT 450
+ END IF T Y+ + + ++R G V V ++ +
Sbjct: 3903 IEENDDPRGIFMFHVTRGAGEVITAYEVPPPLNVLQVPVVRLAGSF-GAVNVYWKASPDS 3961
Query: 451 ANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGIL 510
A D++ + G + F I + IIDD FE E F + L +V +D ++
Sbjct: 3962 AGL-EDFKPSHGILEFADKQVTAMIEITIIDDAEFELTETFNISLISVAGGGRLGDDVVV 4020
Query: 511 EANHVSTLACLGSPSTATVTIFDDDHA-GIFTFEEPVTHVSESI------GIMEVKVLRT 563
TV I +D G+F FEE + ES+ + + V+R+
Sbjct: 4021 -----------------TVVIPQNDSPFGVFGFEEKTVMIDESLSSDDPDSYVTLTVVRS 4063
Query: 564 SGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFF 623
G +G V + + TI+ A+ + G L F E KTI + + D E+++ F
Sbjct: 4064 PGGKGTVRLEW-TIDEKAK---HNLSPLNGTLHFDETESQKTIVLHTLQDTVLEEDRRFT 4119
Query: 624 LEIGEPRLVEMSEKK 638
+++ VE+S K
Sbjct: 4120 IQLISIDEVEISPVK 4134
Score = 49.3 bits (116), Expect = 2e-05
Identities = 63/273 (23%), Positives = 113/273 (41%), Gaps = 28/273 (10%)
Query: 416 YQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS-DYEFTEGTVVFKPGDTQKE 474
++ E+ G + + ++R G V DF ++ +A+ G DY TV F+ G
Sbjct: 4409 FEVEEDVGLIMIPVVRLHGTY-GYVTADFISQSSSASPGGVDYILHGSTVTFQHGQNLSF 4467
Query: 475 IRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDD 534
I + IIDD+ E +E + L+ A+ +L + VS + S S V F +
Sbjct: 4468 INISIIDDNESEFEEPIEILLTG------ATGGAVLGRHLVSRIIIAKSDSPFGVIRFLN 4521
Query: 535 DHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG----GEDFED 590
+ P S I+ + + RT G G + V ++T+ ++ D D
Sbjct: 4522 QSK--ISIANP-----NSTMILSLVLERTGGLLGEIQVNWETVGPNSQEALLPQNRDIAD 4574
Query: 591 TCGELEF--QNDEIVKTISVKVIDDEEYEKNKTFFLEI----GEPRLVEMSEKKALLLNE 644
L + + + V+TI + + EE E +TF +++ GE +L ++ L + E
Sbjct: 4575 PVSGLFYFGEGEGGVRTIILTIYPHEEIEVEETFIIKLHLVKGEAKLDSRAKDVTLTIQE 4634
Query: 645 LG---GFTITGKYLFGQPVFRKVHAREHPILST 674
G G + + + A E P+L T
Sbjct: 4635 FGDPNGVVQFAPETLSKKTYSEPLALEGPLLIT 4667
Score = 47.8 bits (112), Expect = 5e-05
Identities = 42/170 (24%), Positives = 78/170 (45%), Gaps = 12/170 (7%)
Query: 462 GTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACL 521
G ++ + G+T I + I++DD+ E +E FLV+L+ V G+ A S L
Sbjct: 2891 GFLILEEGETAAAINITILEDDVPELEEYFLVNLTYV---------GLTMAASTSFPPRL 2941
Query: 522 GSPSTATVTIFD--DDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEG 579
S I D D G+ +++ V+E+ G + + R+ G+V + + +
Sbjct: 2942 DSEGLTAQVIIDANDGARGVIEWQQSRFEVNETHGSLTLVAQRSREPLGHVSL-FVYAQN 3000
Query: 580 TARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP 629
G D+ T L F + E K +++ ++DD+ E ++ F L + P
Sbjct: 3001 LEAQVGLDYIFTPMILHFADGERYKNVNIMILDDDIPEGDEKFQLILTNP 3050
Score = 47.0 bits (110), Expect = 9e-05
Identities = 68/256 (26%), Positives = 105/256 (41%), Gaps = 45/256 (17%)
Query: 400 VTENDPVSKIF----FEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
+ END +F +G Y E +V L IIR G L F+ +R E +N
Sbjct: 766 ILENDDPGGVFEFSPASRGPYVIKEG-ESVELHIIRSRGSLVKQ-FLHYRVEPRDSN--- 820
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHV 515
++ G + FKPG+ + I + D I E DE++ V LS +H
Sbjct: 821 EFYGNTGVLEFKPGEREIVITLLARLDGIPELDEHYWVVLS----------------SHG 864
Query: 516 STLACLGSPSTATVTIF-DDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPY 574
+ LGS + +TI +DD GI F VS+ + +M + ++G+ I Y
Sbjct: 865 ERESKLGSATIVNITILKNDDPHGIIEF------VSDGLIVM------INESKGDAI--Y 910
Query: 575 KTIEGTARGGGEDFEDTCGELEFQND---EIVKTISVKVIDDEEYEKNKTFFLEIGEPRL 631
+ R G +F D D ++ V D+E+ KN T + + +
Sbjct: 911 SAVYDVVRNRG-NFGDVSVSWVVSPDFTQDVFPVQGTVVFGDQEFSKNITIY-SLPDEIP 968
Query: 632 VEMSEKKALLLNELGG 647
EM E +LLN GG
Sbjct: 969 EEMEEFTVILLNGTGG 984
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 23/176 (13%)
Query: 453 AGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEA 512
A SD G + F+ G+T K + DD+ E +E F++ L +V + SE+
Sbjct: 1503 AKSDLHPISGYLEFRQGETNKSFIISARDDNDEEGEELFILKLVSVYGGARISEEN---- 1558
Query: 513 NHVSTLACLGSPSTATVTIFDDDHA-GIFTFEEP-VTHVSESIGIMEVKVLRTSGARGNV 570
+TA +TI D+A G+F F + ++E + V RT GA V
Sbjct: 1559 ------------TTARLTIQKSDNANGLFGFTGACIPEIAEEGSTISCVVERTRGALDYV 1606
Query: 571 IVPYKTIEGTARGG----GEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTF 622
V Y TI G +DF + G + F + + +++ V+DD+ E N+ F
Sbjct: 1607 HVFY-TISQIETDGINYLVDDFANASGTITFLPWQRSEVLNIYVLDDDIPELNEYF 1661
Score = 43.9 bits (102), Expect = 7e-04
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 1/80 (1%)
Query: 424 TVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDD 483
++ LT+IR G V V F E G D +G + F PG + ++DD+
Sbjct: 166 SMPLTLIREKGTY-GMVMVTFEVEGGPNPPDEDLSPVKGNITFPPGRATVIYNLTVLDDE 224
Query: 484 IFEEDENFLVHLSNVKVSSE 503
+ E DE FL+ L +V+ +E
Sbjct: 225 VPENDEIFLIQLKSVEGGAE 244
Score = 42.7 bits (99), Expect = 0.002
Identities = 53/207 (25%), Positives = 82/207 (39%), Gaps = 30/207 (14%)
Query: 453 AGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEA 512
AG D F E TV T + + L + V + +EA+ +
Sbjct: 5131 AGMDISFPETTVAVAVDTTLIPVETESTTYLSTSKTTTILQPTNVVAIVTEATGVSAIPE 5190
Query: 513 NHVS---TLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESI-----GIMEVKVLRTS 564
V+ T A P ATVT H G F+ + ++ E + EV + RT
Sbjct: 5191 KLVTLHGTPAVSEKPDVATVTANVSIH-GTFSLGPSIVYIEEEMKNGTFNTAEVLIRRTG 5249
Query: 565 GARGNVIVPYKT-------IEGTA---RG-----------GGEDFEDTCGELEFQNDEIV 603
G GNV + KT +E A RG EDFE+ L F + E
Sbjct: 5250 GFTGNVSITVKTFGERCAQMEPNALPFRGIYGISNLTWAVEEEDFEEQTLTLIFLDGERE 5309
Query: 604 KTISVKVIDDEEYEKNKTFFLEIGEPR 630
+ +SV+++DD+E E + F++ + P+
Sbjct: 5310 RKVSVQILDDDEPEGQEFFYVFLTNPQ 5336
Score = 38.9 bits (89), Expect = 0.024
Identities = 51/239 (21%), Positives = 103/239 (43%), Gaps = 34/239 (14%)
Query: 396 VNTEVTENDPVSKIF-FEQGTYQCLENCGT------VALTIIRRGGDLTNTVFVDFRTED 448
V + +ND +F FE+ T E+ + V LT++R G TV +++ ++
Sbjct: 4020 VTVVIPQNDSPFGVFGFEEKTVMIDESLSSDDPDSYVTLTVVRSPGG-KGTVRLEWTIDE 4078
Query: 449 GTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENF---LVHLSNVKVSSEAS 505
A + GT+ F ++QK I + + D + EED F L+ + V++S
Sbjct: 4079 ---KAKHNLSPLNGTLHFDETESQKTIVLHTLQDTVLEEDRRFTIQLISIDEVEISPVKG 4135
Query: 506 EDGILEANHVSTLACLG-SPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS 564
I+ +G +PS+ + I EP + G + ++R
Sbjct: 4136 SASIIIRGDKRASGEVGIAPSSRHILI-----------GEPSAKYN---GTAIISLVRGP 4181
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFF 623
G G V V ++ + +F +T G+L ++++ + ++ ++D+ E+ K+F+
Sbjct: 4182 GILGEVTVFWRIFPPSV----GEFAETSGKLTMRDEQSAVIVVIQALNDDIPEE-KSFY 4235
Score = 38.1 bits (87), Expect = 0.040
Identities = 45/166 (27%), Positives = 70/166 (42%), Gaps = 21/166 (12%)
Query: 461 EGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLAC 520
+GTVVF + K I + + D+I EE E F V L N ++
Sbjct: 944 QGTVVFGDQEFSKNITIYSLPDEIPEEMEEFTVILLNGTGGAK----------------- 986
Query: 521 LGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGT 580
+G+ +TAT+ I +D I+ E V V E VLR +V Y T +G
Sbjct: 987 VGNRTTATLRIRRNDDP-IYFAEPRVVRVQEG-ETANFTVLRNGSVDVTCMVQYATKDGK 1044
Query: 581 ARGGGEDF--EDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFL 624
A DF + L F+ ++IS+ V +D E ++ F++
Sbjct: 1045 ATARERDFIPVEKGETLIFEVGSRQQSISIFVNEDGIPETDEPFYI 1090
Score = 38.1 bits (87), Expect = 0.040
Identities = 59/240 (24%), Positives = 102/240 (42%), Gaps = 37/240 (15%)
Query: 400 VTENDPVSKIFFEQGTYQCLE-NCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYE 458
V+E S++ FE +Q + GT + I RRG + V + T G A E
Sbjct: 4879 VSEKAANSQVGFESTAFQLMNITAGTSHVMISRRG--TYGALSVAWTT--GYAPGLEIPE 4934
Query: 459 F--------TEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGIL 510
F T G++ F G+ +K + + + E F++HLS V+ S+
Sbjct: 4935 FIVVGNMTPTLGSLSFSHGEQRKGVFLWTFPSPGWPEA--FVLHLSGVQSSAPG------ 4986
Query: 511 EANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTH--VSESIGIMEVKVLRTSGARG 568
G+ + + + + G+F F + VSE ++ + V R G
Sbjct: 4987 -----------GAQLRSGFIVAEIEPMGVFQFSTSSRNIIVSEDTQMIRLHVQRLFGFHS 5035
Query: 569 NVI-VPYKTIEGTARGGGEDFEDTC-GELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
++I V Y+T G+A+ EDFE GEL FQ + + +I+D+ E + F++ +
Sbjct: 5036 DLIKVSYQTTAGSAKPL-EDFEPVQNGELFFQKFQTEVDFEITIINDQLSEIEEFFYINL 5094
Score = 36.6 bits (83), Expect = 0.12
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 20/190 (10%)
Query: 425 VALTIIRRGGDLTNTVFVDFRTEDGTANAGS--DYEFTEGTVVFKPGDTQKEIRVGIIDD 482
V + + R G D TV+ + + A + D G+V+F G + I + I D
Sbjct: 673 VYIPLHRDGTDGQATVYWSLKPSGFNSKAVTPDDIGPFNGSVLFLSGQSDTTINITIKGD 732
Query: 483 DIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTF 542
DI E +E + L V V ++ + G S + + +DD G+F F
Sbjct: 733 DIPEMNETVTLSLDRVNVENQVLKSGY--------------TSRDLIILENDDPGGVFEF 778
Query: 543 EEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQ--ND 600
P + I E L +RG+++ + R E + +T G LEF+
Sbjct: 779 -SPASRGPYVIKEGESVELHIIRSRGSLVKQFLHYRVEPRDSNEFYGNT-GVLEFKPGER 836
Query: 601 EIVKTISVKV 610
EIV T+ ++
Sbjct: 837 EIVITLLARL 846
Score = 34.7 bits (78), Expect = 0.45
Identities = 42/199 (21%), Positives = 84/199 (42%), Gaps = 6/199 (3%)
Query: 480 IDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGI 539
ID I+E ++ + +V ++ A+ ++ + +G +A + +
Sbjct: 3481 IDIFIWEMGQSSFRYFQSVDFAAVNRIHSFTPASGIAHILLIGQDMSALYCWNSERNQFS 3540
Query: 540 FTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTAR-GGGEDFEDTCGELEFQ 598
F E P + + + VK L +S ++ + I A DF + GEL F+
Sbjct: 3541 FVLEVPSAY---DVASVTVKSLNSSKNLIALVGAHSHIYELAYISSHSDFIPSSGELIFE 3597
Query: 599 NDEIVKTISVKVIDDEEYEKNKTFFLEIGEPR-LVEMSEKKALLLNELGGFTITGKYLFG 657
E TI+V ++DD EK ++F +++ P+ E+ ++ + L G F
Sbjct: 3598 PGEREATIAVNILDDTVPEKEESFKVQLKNPKGGAEIGINDSVTITILSNDDAYGIVAFA 3657
Query: 658 Q-PVFRKVHAREHPILSTV 675
Q ++++V E L T+
Sbjct: 3658 QNSLYKQVEEMEQDSLVTL 3676
Score = 34.3 bits (77), Expect = 0.58
Identities = 37/159 (23%), Positives = 63/159 (39%), Gaps = 25/159 (15%)
Query: 427 LTIIRRGGDLTNTV--FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDI 484
+T++R GG N +V R + +D + G + F G I + ++DDD+
Sbjct: 417 ITVVRNGGTHGNVSANWVLTRNSTDPSPVTADIRPSSGVLHFAQGQMLATIPLTVVDDDL 476
Query: 485 FEEDENFLVHL--SNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFD-DDHAGIFT 541
EE E +L+ + ++ +E SE P+ I D DD G+ T
Sbjct: 477 PEEAEAYLLQILPHTIRGGAEVSE-----------------PAELLFYIQDSDDVYGLIT 519
Query: 542 F---EEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTI 577
F E S + + R G +G+V + Y +
Sbjct: 520 FFPMENQKIESSPGERYLSLSFTRLGGTKGDVRLLYSVL 558
Score = 34.3 bits (77), Expect = 0.58
Identities = 17/52 (32%), Positives = 31/52 (59%)
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
D+E T++F G+ ++++ V I+DDD E E F V L+N + ++ E+
Sbjct: 5293 DFEEQTLTLIFLDGERERKVSVQILDDDEPEGQEFFYVFLTNPQGGAQIVEE 5344
>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 75.1 bits (183), Expect = 3e-13
Identities = 68/232 (29%), Positives = 98/232 (42%), Gaps = 30/232 (12%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFK 467
I E+ Y E+ + +T+ RRG L T F+ T+D TA D+++ T + F
Sbjct: 1775 ICLEKEYYIVDEDSTFLEVTLTRRGY-LGETSFISIGTKDETAKKDKDFKWKTNKQIQFN 1833
Query: 468 PGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTA 527
PG T RV II D+ +E E F + LS +A L P A
Sbjct: 1834 PGQTTATWRVRIIPDNEYETSETFQIILSE------------------PLMAVLEFPEMA 1875
Query: 528 TVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG--- 584
TV I D E + E IG + + V R+ A +IV T +G+A G
Sbjct: 1876 TVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISS 1935
Query: 585 ---GEDF----EDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP 629
D+ ED L F +E KT V +IDD YE+ ++F + + P
Sbjct: 1936 TVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLP 1987
Score = 58.5 bits (140), Expect = 3e-08
Identities = 66/258 (25%), Positives = 104/258 (40%), Gaps = 44/258 (17%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + S ++ + Y+ E+ G + + + RR GD + + V T G+A
Sbjct: 1878 EIVDPGDESTVYIPEAEYKIEEDIGELLIPV-RRSGDASQELIVICSTRQGSATGTISST 1936
Query: 455 ---SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
SDY E + F +TQK +V IIDD ++EE+E+F VS
Sbjct: 1937 VLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESF-------SVSLRLPVG 1989
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS--- 564
G L A P+T + D + F + HV+ES +EV V R
Sbjct: 1990 GQLGARF---------PTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDL 2040
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFL 624
++ V + E + G D+ L+F ++T V ++DD
Sbjct: 2041 SQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDD----------- 2089
Query: 625 EIGEPRLVEMSEKKALLL 642
+G+P L E EK LLL
Sbjct: 2090 -LGQPTL-EGPEKFELLL 2105
>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 75.1 bits (183), Expect = 3e-13
Identities = 68/232 (29%), Positives = 98/232 (42%), Gaps = 30/232 (12%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFK 467
I E+ Y E+ + +T+ RRG L T F+ T+D TA D+++ T + F
Sbjct: 1775 ICLEKEYYIVDEDSTFLEVTLTRRGY-LGETSFISIGTKDETAKKDKDFKWKTNKQIQFN 1833
Query: 468 PGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTA 527
PG T RV II D+ +E E F + LS +A L P A
Sbjct: 1834 PGQTTATWRVRIIPDNEYETSETFQIILSE------------------PLMAVLEFPEMA 1875
Query: 528 TVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG--- 584
TV I D E + E IG + + V R+ A +IV T +G+A G
Sbjct: 1876 TVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISS 1935
Query: 585 ---GEDF----EDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP 629
D+ ED L F +E KT V +IDD YE+ ++F + + P
Sbjct: 1936 TVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLP 1987
Score = 58.5 bits (140), Expect = 3e-08
Identities = 66/258 (25%), Positives = 104/258 (40%), Gaps = 44/258 (17%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + S ++ + Y+ E+ G + + + RR GD + + V T G+A
Sbjct: 1878 EIVDPGDESTVYIPEAEYKIEEDIGELLIPV-RRSGDASQELIVICSTRQGSATGTISST 1936
Query: 455 ---SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
SDY E + F +TQK +V IIDD ++EE+E+F VS
Sbjct: 1937 VLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESF-------SVSLRLPVG 1989
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS--- 564
G L A P+T + D + F + HV+ES +EV V R
Sbjct: 1990 GQLGARF---------PTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDL 2040
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFL 624
++ V + E + G D+ L+F ++T V ++DD
Sbjct: 2041 SQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDD----------- 2089
Query: 625 EIGEPRLVEMSEKKALLL 642
+G+P L E EK LLL
Sbjct: 2090 -LGQPTL-EGPEKFELLL 2105
>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 75.1 bits (183), Expect = 3e-13
Identities = 68/232 (29%), Positives = 98/232 (42%), Gaps = 30/232 (12%)
Query: 409 IFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFK 467
I E+ Y E+ + +T+ RRG L T F+ T+D TA D+++ T + F
Sbjct: 1775 ICLEKEYYIVDEDSTFLEVTLTRRGY-LGETSFISIGTKDETAKKDKDFKWKTNKQIQFN 1833
Query: 468 PGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTA 527
PG T RV II D+ +E E F + LS +A L P A
Sbjct: 1834 PGQTTATWRVRIIPDNEYETSETFQIILSE------------------PLMAVLEFPEMA 1875
Query: 528 TVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGG--- 584
TV I D E + E IG + + V R+ A +IV T +G+A G
Sbjct: 1876 TVEIVDPGDESTVYIPEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISS 1935
Query: 585 ---GEDF----EDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP 629
D+ ED L F +E KT V +IDD YE+ ++F + + P
Sbjct: 1936 TVLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLP 1987
Score = 58.5 bits (140), Expect = 3e-08
Identities = 66/258 (25%), Positives = 104/258 (40%), Gaps = 44/258 (17%)
Query: 399 EVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAG---- 454
E+ + S ++ + Y+ E+ G + + + RR GD + + V T G+A
Sbjct: 1878 EIVDPGDESTVYIPEAEYKIEEDIGELLIPV-RRSGDASQELIVICSTRQGSATGTISST 1936
Query: 455 ---SDY----EFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASED 507
SDY E + F +TQK +V IIDD ++EE+E+F VS
Sbjct: 1937 VLFSDYISRPEDHTSILHFDKNETQKTCQVLIIDDSLYEEEESF-------SVSLRLPVG 1989
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS--- 564
G L A P+T + D + F + HV+ES +EV V R
Sbjct: 1990 GQLGARF---------PTTKVTILADRYDEPVLHFGDAEYHVNESARYVEVCVWRRGTDL 2040
Query: 565 GARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFL 624
++ V + E + G D+ L+F ++T V ++DD
Sbjct: 2041 SQPSSIAVRSRKSEQESAEAGTDYVGISRNLDFAPGVRMQTFQVTILDD----------- 2089
Query: 625 EIGEPRLVEMSEKKALLL 642
+G+P L E EK LLL
Sbjct: 2090 -LGQPTL-EGPEKFELLL 2105
>gi|79749430 FRAS1-related extracellular matrix protein 2 precursor
[Homo sapiens]
Length = 3169
Score = 70.5 bits (171), Expect = 7e-12
Identities = 59/213 (27%), Positives = 87/213 (40%), Gaps = 30/213 (14%)
Query: 429 IIRRGGDLTNTVFVDFRTEDGTANAGSDYEF-TEGTVVFKPGDTQKEIRVGIIDDDIFEE 487
+++R G L T F+ T D TA D++ + V F PG T+ RV I+ D E+
Sbjct: 1790 VLKRRGYLGETSFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILSDGEHEQ 1849
Query: 488 DENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVT 547
E F V LS LA L P+ ATV I D +
Sbjct: 1850 SETFQVVLSE------------------PVLAALEFPTVATVEIVDPGDEPTVFIPQSKY 1891
Query: 548 HVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARG-------GGEDF----EDTCGELE 596
V E +G + + + R+ ++V T +GTA G D+ ED +
Sbjct: 1892 SVEEDVGELFIPIRRSGDVSQELMVVCYTQQGTATGTVPTSVLSYSDYISRPEDHTSVVR 1951
Query: 597 FQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEP 629
F DE K + +IDD YE+ +TF + + P
Sbjct: 1952 FDKDEREKLCRIVIIDDSLYEEEETFHVLLSMP 1984
Score = 68.6 bits (166), Expect = 3e-11
Identities = 69/254 (27%), Positives = 114/254 (44%), Gaps = 19/254 (7%)
Query: 400 VTENDPVS---KIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSD 456
V+ ND VS K+ F++ Y E+ G + +T+I R GD+ V T G+A D
Sbjct: 2118 VSINDSVSDLPKMQFKERIYTGSESDGQI-VTMIHRTGDVQYRSSVRCYTRQGSAQVMMD 2176
Query: 457 YEFTEGT----VVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEA 512
+E T + F PG+T+K + ++DD ++EE E + L + +S G
Sbjct: 2177 FEERPNTDTSIITFLPGETEKPCILELMDDVLYEEVEELRLVLGTPQSNSPF---GAAVG 2233
Query: 513 NHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIV 572
TL + + TV F + + +EP ES+ ++ + V+R IV
Sbjct: 2234 EQNETLIRIRDDADKTVIKFGETKFSVTEPKEP----GESV-VIRIPVIRQGDTSKVSIV 2288
Query: 573 PYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTF--FLEIGEPR 630
T +G+A GED+ E+EF+ E + ++V D E + F L+ E
Sbjct: 2289 RVHTKDGSAT-SGEDYHPVSEEIEFKEGETQHVVEIEVTFDGVREMREAFTVHLKPDENM 2347
Query: 631 LVEMSEKKALLLNE 644
+ EM KA++ E
Sbjct: 2348 IAEMQLTKAIVYIE 2361
Score = 58.2 bits (139), Expect = 4e-08
Identities = 66/244 (27%), Positives = 105/244 (43%), Gaps = 30/244 (12%)
Query: 398 TEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFR---TEDGTANAG 454
T V + D +F Y E+ G V + + R G DL+ + V R T+ +A+AG
Sbjct: 1999 TIVPDKDDEPIFYFGDVEYSVDESAGYVEVQVWRTGTDLSKSSSVTVRSRKTDPPSADAG 2058
Query: 455 SDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANH 514
+DY + F PG + +RV I+DD + + +GI +
Sbjct: 2059 TDYVGISRNLDFAPGVNMQPVRVVILDD------------------LGQPALEGIEKFEL 2100
Query: 515 VSTL---ACLGSPSTATVTIFDD-DHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNV 570
V + A LG PS ATV+I D F+E + SES G + + RT +
Sbjct: 2101 VLRMPMNAALGEPSKATVSINDSVSDLPKMQFKERIYTGSESDGQIVTMIHRTGDVQYRS 2160
Query: 571 IVPYKTIEGTARGGGEDFED----TCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEI 626
V T +G+A+ DFE+ + F E K ++++DD YE+ + L +
Sbjct: 2161 SVRCYTRQGSAQ-VMMDFEERPNTDTSIITFLPGETEKPCILELMDDVLYEEVEELRLVL 2219
Query: 627 GEPR 630
G P+
Sbjct: 2220 GTPQ 2223
Score = 47.8 bits (112), Expect = 5e-05
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 6/115 (5%)
Query: 425 VALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDI 484
+ + +IR+G D + V T+DG+A +G DY + FK G+TQ + + + D +
Sbjct: 2272 IRIPVIRQG-DTSKVSIVRVHTKDGSATSGEDYHPVSEEIEFKEGETQHVVEIEVTFDGV 2330
Query: 485 FEEDENFLVHL--SNVKVSSEASEDGILEANHVSTLACLGSPST---ATVTIFDD 534
E E F VHL ++ I+ +S++A + PS ++ ++DD
Sbjct: 2331 REMREAFTVHLKPDENMIAEMQLTKAIVYIEEMSSMADVTFPSVPQIVSLLMYDD 2385
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 68.9 bits (167), Expect = 2e-11
Identities = 78/286 (27%), Positives = 122/286 (42%), Gaps = 38/286 (13%)
Query: 430 IRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGT----VVFKPGDTQKEIRVGIIDDDIF 485
I R GDL+ V T+ +A D+E + + F GD K V I DD +F
Sbjct: 2940 ITRSGDLSYESSVRCYTQSHSAQVMEDFEERQNADSSRITFLKGDKVKNCTVYIHDDSMF 2999
Query: 486 EEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEP 545
E +E F V+L G+ NH S A +G + AT+TI +D+ A FEE
Sbjct: 3000 EPEEQFRVYL------------GLPLGNHWSG-ARIGKNNMATITISNDEDAPTIEFEEA 3046
Query: 546 VTHVSE-----SIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQND 600
V E +I I+ +KV+R V T +G+A+ G D+ L+F
Sbjct: 3047 AYQVREPAGPDAIAILNIKVIRRGDQNRTSKVRCSTRDGSAQ-SGVDYYPKSRVLKFSPG 3105
Query: 601 EIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPV 660
V+++ +E+ E +++F L +G VE LG T + Q
Sbjct: 3106 VDHIFFKVEILSNEDREWHESFSLVLGPDDPVEA---------VLGDVTTATVTILDQEA 3156
Query: 661 FRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPIL 706
+ PI V+T+AD YD + +T +E ++ G P++
Sbjct: 3157 AGSLILPAPPI---VVTLAD-YDHVEEVT--KEGVKKSPSPGYPLV 3196
Score = 53.1 bits (126), Expect = 1e-06
Identities = 45/150 (30%), Positives = 64/150 (42%), Gaps = 20/150 (13%)
Query: 400 VTENDPVSKIFFEQGTYQCLENCGTVALTIIR----RGGDLTNTVFVDFRTEDGTANAGS 455
++ ++ I FE+ YQ E G A+ I+ R GD T V T DG+A +G
Sbjct: 3032 ISNDEDAPTIEFEEAAYQVREPAGPDAIAILNIKVIRRGDQNRTSKVRCSTRDGSAQSGV 3091
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHV 515
DY + F PG +V I+ ++ E E+F + L D +E
Sbjct: 3092 DYYPKSRVLKFSPGVDHIFFKVEILSNEDREWHESFSLVL---------GPDDPVE---- 3138
Query: 516 STLACLGSPSTATVTIFDDDHAGIFTFEEP 545
A LG +TATVTI D + AG P
Sbjct: 3139 ---AVLGDVTTATVTILDQEAAGSLILPAP 3165
Score = 50.1 bits (118), Expect = 1e-05
Identities = 59/254 (23%), Positives = 109/254 (42%), Gaps = 38/254 (14%)
Query: 401 TENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFT 460
TE++P + F++ Y E+ G + I R+G D ++ V T +A S Y
Sbjct: 2669 TEDEPTLE--FDKKIYWVNESAGFLFAPIERKG-DASSIVSAICYTVPKSAMGSSLYALE 2725
Query: 461 EGT------------VVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDG 508
G+ V+F PG T V +IDD +EE+E F + L ++AS++
Sbjct: 2726 SGSDFKSRGMSAASRVIFGPGVTMSTCDVMLIDDSEYEEEEEFEIAL------ADASDN- 2778
Query: 509 ILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTS---G 565
A +G +TA V I + A + VSE G +++ V+R
Sbjct: 2779 ----------ARIGRVATAKVLISGPNDASTVSLGNTAFTVSEDAGTVKIPVIRHGTDLS 2828
Query: 566 ARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEY---EKNKTF 622
+V + + + G D+ + ++EF I + ++ ++DD +Y E +TF
Sbjct: 2829 TFASVWCATRPSDPASATPGVDYVPSSRKVEFGPGVIEQYCTLTILDDTQYPVIEGLETF 2888
Query: 623 FLEIGEPRLVEMSE 636
+ + + E+++
Sbjct: 2889 VVFLSSAQGAELTK 2902
Score = 49.7 bits (117), Expect = 1e-05
Identities = 54/257 (21%), Positives = 108/257 (42%), Gaps = 31/257 (12%)
Query: 395 EVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVD--FRTEDGTAN 452
E+ T + V + + GT + + N G L + G TN + + T +
Sbjct: 2418 EIMTAAPQPFRVDILPVDDGTPRIVTNLGLQWLEYM--DGKATNLITKKELLTMDPDTED 2475
Query: 453 AGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDEN-----FLVHLSNVKVSSEASED 507
A YE T G K G + +++ G +ED N +++H ++ ++ +
Sbjct: 2476 AQLVYEITTGP---KHGFVENKLQPGRAAATFTQEDVNLGLIRYVLHKEKIREMMDSFQF 2532
Query: 508 GILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGAR 567
+ ++ P+ + +F + + +F+ +VSE G + V V RT
Sbjct: 2533 LVKDSK----------PNVVSDNVFHIQWS-LISFKYTSYNVSEKAGSVSVTVQRTGNLN 2581
Query: 568 GNVIVPYKTIEGTARG--------GGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKN 619
IV +T +GTA G +D+ + G+++F E K+ ++ + DD+ +E
Sbjct: 2582 QYAIVLCRTEQGTASSSSRVSSQPGQQDYVEYAGQVQFDEREDTKSCTIVINDDDVFENV 2641
Query: 620 KTFFLEIGEPRLVEMSE 636
++F +E+ P + E
Sbjct: 2642 ESFTVELSMPAYALLGE 2658
>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 3 [Homo sapiens]
Length = 644
Score = 68.2 bits (165), Expect = 4e-11
Identities = 51/177 (28%), Positives = 83/177 (46%), Gaps = 14/177 (7%)
Query: 758 EDDDDDECGEEKLPSCFDYVMHFL-TVFWK-------VLFAFVPPTEY--WNGW--ACFI 805
E++++DE +E + FD L TV W VL+ VP W W F
Sbjct: 422 EEEEEDEDDDEGPYTPFDTPSGKLETVKWAFTWPLSFVLYFTVPNCNKPRWEKWFMVTFA 481
Query: 806 VSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADA 865
S L I + + + + G T+G+ D + + F+A GTSVPD AS + A Q D
Sbjct: 482 SSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGM-GDM 540
Query: 866 SIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINV 922
++ N GSN ++ +G+G+ W++ + G +++ L +SV L F+ V
Sbjct: 541 AVSNSIGSNVFDILIGLGLPWALQTL-AVDYGSYIRLNSRGLIYSVGLLLASVFVTV 596
Score = 58.5 bits (140), Expect = 3e-08
Identities = 65/243 (26%), Positives = 100/243 (41%), Gaps = 48/243 (19%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 112 LHVLCAIYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 153
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSSAPE+ SVI V T GD+G TIVGSA FN+ II +C
Sbjct: 154 FMAAGSSAPELFTSVIGVF---ITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQ------ 204
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGV------VEVWEGLLTFFFFPICVVFAWVA 252
++W + + +Y LSVI+ V V WE L+ + I +V
Sbjct: 205 -----VVALSSWCLLRDS-IYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVI---- 254
Query: 253 DRRLLFYKYVYKRY-RAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLE 311
+ + +++ + R K G ++ + D VV NF A V+
Sbjct: 255 ---MKYNACIHQCFERRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIM 311
Query: 312 VDE 314
VDE
Sbjct: 312 VDE 314
Score = 35.4 bits (80), Expect = 0.26
Identities = 33/139 (23%), Positives = 54/139 (38%), Gaps = 21/139 (15%)
Query: 831 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 890
L + V F+A G+S P+ F S + + D +G + GS N+ IGV A
Sbjct: 145 LSEDVAGATFMAAGSSAPELFTSVIGVFITK-GDVGVGTIVGSAVFNILCIIGVCGLFA- 202
Query: 891 IYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCL 950
G+ +S L +T+ + I + V +Y + S +
Sbjct: 203 ------GQVVALSSWCLLRDSIYYTL-SVIALIVFIYDEK------------VSWWESLV 243
Query: 951 FVLLWLLYIFFSSLEAYCH 969
VL++L+YI A H
Sbjct: 244 LVLMYLIYIVIMKYNACIH 262
>gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo
sapiens]
Length = 558
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863
FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q
Sbjct: 393 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 451
Query: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 913
D ++ N GSN ++ +G+GV W + + G K++ L +SV L
Sbjct: 452 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 500
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 38 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 79
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++
Sbjct: 80 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 134
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242
++ S++ + +++ I + WEGL+ +
Sbjct: 135 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 174
Score = 36.6 bits (83), Expect = 0.12
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 831 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 890
L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A
Sbjct: 71 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 129
Query: 891 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 920
+ V ++ +++++ + FI
Sbjct: 130 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 157
>gi|29788985 solute carrier family 24 member 4 isoform 2 precursor
[Homo sapiens]
Length = 586
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863
FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q
Sbjct: 421 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 479
Query: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 913
D ++ N GSN ++ +G+GV W + + G K++ L +SV L
Sbjct: 480 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 528
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/226 (23%), Positives = 96/226 (42%), Gaps = 29/226 (12%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 85 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 126
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++
Sbjct: 127 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 181
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLF 258
++ S++ + +++ I + WEGL+ + ++ + F
Sbjct: 182 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAF 237
Query: 259 YKYVYKRYRAGKQRGMIIEHEGDRPS-SKTEIEMDGKVVNSHVENF 303
+ K G +E ++P K + M ++++S F
Sbjct: 238 FTVKQKSIANGNPVNSELEAVKEKPQYGKNPVVMVDEIMSSSPPKF 283
Score = 36.6 bits (83), Expect = 0.12
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 831 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 890
L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A
Sbjct: 118 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 176
Query: 891 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 920
+ V ++ +++++ + FI
Sbjct: 177 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 204
>gi|24111228 solute carrier family 24 member 4 isoform 1 precursor
[Homo sapiens]
Length = 605
Score = 65.5 bits (158), Expect = 2e-10
Identities = 36/110 (32%), Positives = 58/110 (52%), Gaps = 2/110 (1%)
Query: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863
FI + L I + + + L + G T+G+ D + + F+A GTSVPD AS + A Q
Sbjct: 440 FITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQG-LG 498
Query: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTL 913
D ++ N GSN ++ +G+GV W + + G K++ L +SV L
Sbjct: 499 DMAVSNTIGSNVFDILVGLGVPWGLQTMV-VNYGSTVKINSRGLVYSVVL 547
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 28/164 (17%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + +YMF ++I+ D F + S+E I + +E V+ T
Sbjct: 85 LHILGALYMFYALAIVCDDFFVPSLEKICERLH------------------LSEDVAGAT 126
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSS PE+ SVI V T GD+G TIVGSA FN+ II +C G+ ++
Sbjct: 127 FMAAGSSTPELFASVIGVF---ITHGDVGVGTIVGSAVFNILCIIGVCGLFA--GQVVRL 181
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFF 242
++ S++ + +++ I + WEGL+ +
Sbjct: 182 ----TWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILY 221
Score = 36.6 bits (83), Expect = 0.12
Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 831 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAA 890
L + V F+A G+S P+ FAS V + D +G + GS N+ IGV A
Sbjct: 118 LSEDVAGATFMAAGSSTPELFAS-VIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAG 176
Query: 891 IYHAANGEQFKVSPGTLAFSVTLFTIFAFI 920
+ V ++ +++++ + FI
Sbjct: 177 --QVVRLTWWAVCRDSVYYTISVIVLIVFI 204
>gi|45504369 solute carrier family 24, member 5 [Homo sapiens]
Length = 500
Score = 63.5 bits (153), Expect = 9e-10
Identities = 50/169 (29%), Positives = 82/169 (48%), Gaps = 28/169 (16%)
Query: 80 VYFVAMVYMFLGVSIIADR-FMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
+YF+ +VYMF+ +SI+ D F+ S+E+I+ ++ V+ T
Sbjct: 71 IYFLIIVYMFMAISIVCDEYFLPSLEIISESLG------------------LSQDVAGTT 112
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA GSSAPE++ + + V T GD+G STI+GSA +N+ I A C + +
Sbjct: 113 FMAAGSSAPELVTAFLGVF---ITKGDIGISTILGSAIYNLLGICAACGLL--SNTVSTL 167
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVV 247
+F AA++I A +L +I V +EG L + + V+
Sbjct: 168 SCWPLFRDCAAYTISAAA----VLGIIYDNQVYWYEGALLLLIYGLYVL 212
Score = 52.0 bits (123), Expect = 3e-06
Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 15/153 (9%)
Query: 783 VFW-------KVLFAFVPPT--EYWNGW--ACFIVSILMIGLLTAFIGDLASHFGCTIGL 831
+FW +LF P ++W + F +S + I T + + + G T+ +
Sbjct: 306 IFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAFTYILVWMVTITGETLEI 365
Query: 832 KDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSI--A 889
D+V + +A GTS+PDT AS + A + + D ++ N+ GSN ++ L +G+ W I A
Sbjct: 366 PDTVMGLTLLAAGTSIPDTIASVLVARKGK-GDMAMSNIVGSNVFDM-LCLGIPWFIKTA 423
Query: 890 AIYHAANGEQFKVSPGTLAFSVTLFTIFAFINV 922
I +A E + S+ + IF F+ V
Sbjct: 424 FINGSAPAEVNSRGLTYITISLNISIIFLFLAV 456
Score = 35.8 bits (81), Expect = 0.20
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 8/84 (9%)
Query: 99 FMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCG 158
FMS+I + + + GET + +TV LTL+A G+S P+ + SV+
Sbjct: 339 FMSAIWISAFTYILVWMVTITGETLEIP-----DTVMGLTLLAAGTSIPDTIASVLVA-- 391
Query: 159 HNFTAGDLGPSTIVGSAAFNMFII 182
GD+ S IVGS F+M +
Sbjct: 392 -RKGKGDMAMSNIVGSNVFDMLCL 414
>gi|9966787 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 2 [Homo sapiens]
Length = 661
Score = 58.5 bits (140), Expect = 3e-08
Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 38/175 (21%)
Query: 80 VYFVAMVYMFLGVSIIADRF-MSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ + M+YMF+ ++I+ D F + S+ VIT +++ I ++ V+ T
Sbjct: 137 LHVIGMIYMFIALAIVCDEFFVPSLTVIT---EKLGI---------------SDDVAGAT 178
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA G SAPE+ S+I V ++G TIVGSA FN+ +I +C +R+I
Sbjct: 179 FMAAGGSAPELFTSLIGVF---IAHSNVGIGTIVGSAVFNILFVIGMCALF-----SREI 230
Query: 199 KHLRVFFVTAAWSIFAYTWLYII-----LSVISPGVVEVWEGLLTFFFFPICVVF 248
+L W +F YI+ + V+ WE LL + VVF
Sbjct: 231 LNL------TWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVF 279
Score = 50.4 bits (119), Expect = 8e-06
Identities = 32/127 (25%), Positives = 58/127 (45%), Gaps = 2/127 (1%)
Query: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863
F SI I + + + A G TIG+ + + + +A GTS+PD S + A +
Sbjct: 503 FFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKG-LG 561
Query: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG 923
D ++ + GSN ++ +G+ + W + + H S G V LF + F+ +
Sbjct: 562 DMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQPVAVS-SNGLFCAIVLLFIMLLFVILS 620
Query: 924 VLLYRRR 930
+ L + R
Sbjct: 621 IALCKWR 627
Score = 35.4 bits (80), Expect = 0.26
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 829 IGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGV 884
+G+ D V F+A G S P+ F S + +++ IG + GS N+ IG+
Sbjct: 168 LGISDDVAGATFMAAGGSAPELFTSLIGVF-IAHSNVGIGTIVGSAVFNILFVIGM 222
Score = 32.0 bits (71), Expect = 2.9
Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 131 NETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIAL 185
+E + LT++A G+S P+++ SVI GD+ S+ VGS F++ + + L
Sbjct: 531 SEEIMGLTILAAGTSIPDLITSVIVA---RKGLGDMAVSSSVGSNIFDITVGLPL 582
>gi|54607027 integrin beta 4 isoform 2 precursor [Homo sapiens]
Length = 1805
Score = 50.8 bits (120), Expect = 6e-06
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 396 VNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
VN + + + FEQ + + +IRR D + V +RT+DGTA
Sbjct: 979 VNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQ-VSYRTQDGTAQGNR 1037
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIID----DDIF--EEDENFLVHLSNVKVSSEASEDGI 509
DY EG ++F+PG+ KE++V +++ D + + F V LSN K
Sbjct: 1038 DYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFG-------- 1089
Query: 510 LEANHVSTLACLGSPSTATVTIFDDD 535
A LG P + T+ I D D
Sbjct: 1090 ---------AHLGQPHSTTIIIRDPD 1106
Score = 48.1 bits (113), Expect = 4e-05
Identities = 46/196 (23%), Positives = 83/196 (42%), Gaps = 25/196 (12%)
Query: 441 FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKV 500
F D + G +D + G V F+ G ++RV + ++++ LV +V
Sbjct: 911 FHDLKVAPGYYTLTADQD-ARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPA 969
Query: 501 SSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKV 560
+ A LG +TI + + +FE+P VS + + V
Sbjct: 970 GT----------------ATLGR-RLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPV 1012
Query: 561 LRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYE--- 617
+R G V Y+T +GTA+ G D+ GEL FQ E K + VK+++ +E +
Sbjct: 1013 IRRVLDGGKSQVSYRTQDGTAQ-GNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLL 1071
Query: 618 ---KNKTFFLEIGEPR 630
+ + F +++ P+
Sbjct: 1072 RGRQVRRFHVQLSNPK 1087
>gi|54607035 integrin beta 4 isoform 1 precursor [Homo sapiens]
Length = 1822
Score = 50.8 bits (120), Expect = 6e-06
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 396 VNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
VN + + + FEQ + + +IRR D + V +RT+DGTA
Sbjct: 979 VNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQ-VSYRTQDGTAQGNR 1037
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIID----DDIF--EEDENFLVHLSNVKVSSEASEDGI 509
DY EG ++F+PG+ KE++V +++ D + + F V LSN K
Sbjct: 1038 DYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFG-------- 1089
Query: 510 LEANHVSTLACLGSPSTATVTIFDDD 535
A LG P + T+ I D D
Sbjct: 1090 ---------AHLGQPHSTTIIIRDPD 1106
Score = 48.1 bits (113), Expect = 4e-05
Identities = 46/196 (23%), Positives = 83/196 (42%), Gaps = 25/196 (12%)
Query: 441 FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKV 500
F D + G +D + G V F+ G ++RV + ++++ LV +V
Sbjct: 911 FHDLKVAPGYYTLTADQD-ARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPA 969
Query: 501 SSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKV 560
+ A LG +TI + + +FE+P VS + + V
Sbjct: 970 GT----------------ATLGR-RLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPV 1012
Query: 561 LRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYE--- 617
+R G V Y+T +GTA+ G D+ GEL FQ E K + VK+++ +E +
Sbjct: 1013 IRRVLDGGKSQVSYRTQDGTAQ-GNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLL 1071
Query: 618 ---KNKTFFLEIGEPR 630
+ + F +++ P+
Sbjct: 1072 RGRQVRRFHVQLSNPK 1087
>gi|54607033 integrin beta 4 isoform 3 precursor [Homo sapiens]
Length = 1752
Score = 50.8 bits (120), Expect = 6e-06
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 24/146 (16%)
Query: 396 VNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGS 455
VN + + + FEQ + + +IRR D + V +RT+DGTA
Sbjct: 979 VNITIIKEQARDVVSFEQPEFSVSRGDQVARIPVIRRVLDGGKSQ-VSYRTQDGTAQGNR 1037
Query: 456 DYEFTEGTVVFKPGDTQKEIRVGIID----DDIF--EEDENFLVHLSNVKVSSEASEDGI 509
DY EG ++F+PG+ KE++V +++ D + + F V LSN K
Sbjct: 1038 DYIPVEGELLFQPGEAWKELQVKLLELQEVDSLLRGRQVRRFHVQLSNPKFG-------- 1089
Query: 510 LEANHVSTLACLGSPSTATVTIFDDD 535
A LG P + T+ I D D
Sbjct: 1090 ---------AHLGQPHSTTIIIRDPD 1106
Score = 48.1 bits (113), Expect = 4e-05
Identities = 46/196 (23%), Positives = 83/196 (42%), Gaps = 25/196 (12%)
Query: 441 FVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKV 500
F D + G +D + G V F+ G ++RV + ++++ LV +V
Sbjct: 911 FHDLKVAPGYYTLTADQD-ARGMVEFQEGVELVDVRVPLFIRPEDDDEKQLLVEAIDVPA 969
Query: 501 SSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKV 560
+ A LG +TI + + +FE+P VS + + V
Sbjct: 970 GT----------------ATLGR-RLVNITIIKEQARDVVSFEQPEFSVSRGDQVARIPV 1012
Query: 561 LRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYE--- 617
+R G V Y+T +GTA+ G D+ GEL FQ E K + VK+++ +E +
Sbjct: 1013 IRRVLDGGKSQVSYRTQDGTAQ-GNRDYIPVEGELLFQPGEAWKELQVKLLELQEVDSLL 1071
Query: 618 ---KNKTFFLEIGEPR 630
+ + F +++ P+
Sbjct: 1072 RGRQVRRFHVQLSNPK 1087
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 50.8 bits (120), Expect = 6e-06
Identities = 44/168 (26%), Positives = 78/168 (46%), Gaps = 28/168 (16%)
Query: 80 VYFVAMVYMFLGVSIIADR-FMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLT 138
++ M+Y+F+ ++I+ D F+ ++ VIT + + +E V+ T
Sbjct: 457 LHVFGMMYVFVALAIVCDEYFVPALGVITDKLQI------------------SEDVAGAT 498
Query: 139 LMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKI 198
MA G SAPE+ S+I V + ++G TIVGSA FN+ +I C +R+I
Sbjct: 499 FMAAGGSAPELFTSLIGVF---ISHSNVGIGTIVGSAVFNILFVIGTCSLF-----SREI 550
Query: 199 KHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICV 246
+L + + S + + +IL + ++ WE LL + V
Sbjct: 551 LNLTWWPLFRDVSFYILDLIMLILFFLD-SLIAWWESLLLLLAYAFYV 597
Score = 49.7 bits (117), Expect = 1e-05
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 2/117 (1%)
Query: 804 FIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYA 863
F+ SI+ I + + + A G TIG+ + + + +A GTS+PD S + A +
Sbjct: 941 FLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKG-LG 999
Query: 864 DASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFI 920
D ++ + GSN ++ +G+ V W + ++ + S G V LF + F+
Sbjct: 1000 DMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVS-SNGLFCAIVLLFLMLLFV 1055
Score = 31.6 bits (70), Expect = 3.8
Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 131 NETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFI 181
+E + LT++A G+S P+++ SVI GD+ S+ VGS F++ +
Sbjct: 969 SEEIMGLTILAAGTSIPDLITSVIVA---RKGLGDMAVSSSVGSNIFDITV 1016
Score = 30.8 bits (68), Expect = 6.4
Identities = 15/53 (28%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 831 LKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIG 883
+ + V F+A G S P+ F S + +++ IG + GS N+ IG
Sbjct: 490 ISEDVAGATFMAAGGSAPELFTSLIGVF-ISHSNVGIGTIVGSAVFNILFVIG 541
>gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]
Length = 2179
Score = 45.1 bits (105), Expect = 3e-04
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Query: 407 SKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVV- 465
S I + Q Y+ EN G + L IIRRG + ++ FV + +A G D+ ++
Sbjct: 1741 SHIEWSQTEYEVCENVGLLPLEIIRRGYSM-DSAFVGIKVNQVSAAVGKDFTVIPSKLIQ 1799
Query: 466 FKPGDTQKEIRVGIIDDDIFEEDENFLVHLSN 497
F PG + K + I D + E+DE F V L++
Sbjct: 1800 FDPGMSTKMWNIAITYDGLEEDDEVFEVILNS 1831
>gi|39995086 solute carrier family 24 member 6 [Homo sapiens]
Length = 584
Score = 36.6 bits (83), Expect = 0.12
Identities = 37/157 (23%), Positives = 68/157 (43%), Gaps = 17/157 (10%)
Query: 788 LFAFVPPT------EYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFV 841
+F PP+ + W ++ IL + F +L++ T+ L +V V F+
Sbjct: 87 IFCHFPPSLLPLAVTLYVSWLLYLFLILGVTAAKFFCPNLSA-ISTTLKLSHNVAGVTFL 145
Query: 842 ALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFK 901
A G PD F++ VA + A ++G + G+ V V + +I + AA+ F+
Sbjct: 146 AFGNGAPDIFSALVAFSDPHTAGLALGALFGA-GVLVTTVVAGGITILHPFMAASRPFFR 204
Query: 902 VSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELG 938
+ + V +F F ++L+R R + LG
Sbjct: 205 ---DIVFYMVAVFLTF------LMLFRGRVTLAWALG 232
>gi|209862785 anoctamin 2 [Homo sapiens]
Length = 998
Score = 36.2 bits (82), Expect = 0.15
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 27/105 (25%)
Query: 688 LTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQ 747
LT EEEE R E RP YE K +K++K++N + V Q
Sbjct: 467 LTGIEEEEERAQEHSRP--------------EYETK-VREKMLKESNQSAV--------Q 503
Query: 748 FIEAITVSAGEDDDDDE-CGEEKLPSCFDYVMHFLTVFWKVLFAF 791
+E T G++DD+D+ +++ P Y+M+F ++ + + F
Sbjct: 504 KLETNTTECGDEDDEDKLTWKDRFPG---YLMNFASILFMIALTF 545
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,968,755
Number of Sequences: 37866
Number of extensions: 1532734
Number of successful extensions: 4774
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 4530
Number of HSP's gapped (non-prelim): 145
length of query: 973
length of database: 18,247,518
effective HSP length: 112
effective length of query: 861
effective length of database: 14,006,526
effective search space: 12059618886
effective search space used: 12059618886
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.