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Search of human proteins with 10835145
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10835145 interleukin 1, beta proprotein [Homo sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10835145 interleukin 1, beta proprotein [Homo sapiens] 550 e-157
gi|27894313 interleukin 1 family, member 8 isoform 2 [Homo sapiens] 61 9e-10
gi|7657092 interleukin 1 family, member 6 (epsilon) [Homo sapiens] 59 6e-09
gi|27894321 interleukin 1 receptor antagonist isoform 4 [Homo sa... 53 3e-07
gi|27894319 interleukin 1 receptor antagonist isoform 1 precurso... 53 3e-07
gi|27894317 interleukin 1 receptor antagonist isoform 2 [Homo sa... 53 3e-07
gi|10835147 interleukin 1 receptor antagonist isoform 3 [Homo sa... 53 3e-07
gi|27894330 interleukin 1, alpha proprotein [Homo sapiens] 47 1e-05
gi|27894310 interleukin 1 family, member 5 [Homo sapiens] 46 3e-05
gi|6912432 interleukin 1 family, member 5 [Homo sapiens] 46 3e-05
gi|9665234 interleukin 1 family, member 9 [Homo sapiens] 46 4e-05
gi|27894307 interleukin 1 family, member 10 [Homo sapiens] 44 1e-04
gi|27894304 interleukin 1 family, member 10 [Homo sapiens] 44 1e-04
gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein ... 39 0.006
gi|27894298 interleukin 1 family, member 7 isoform 3 [Homo sapiens] 37 0.024
gi|27894296 interleukin 1 family, member 7 isoform 2 [Homo sapiens] 36 0.040
gi|27894302 interleukin 1 family, member 7 isoform 5 [Homo sapiens] 36 0.040
gi|27894300 interleukin 1 family, member 7 isoform 4 [Homo sapiens] 35 0.053
gi|31657117 SMEK homolog 1, suppressor of mek1 [Homo sapiens] 30 2.2
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 30 2.9
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 30 2.9
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 30 2.9
gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo sapiens] 29 3.8
gi|39930397 SMEK homolog 2, suppressor of mek1 isoform 2 [Homo s... 29 4.9
gi|171916095 SMEK homolog 2, suppressor of mek1 isoform 1 [Homo ... 29 4.9
gi|189491771 thyroid hormone receptor, beta [Homo sapiens] 28 8.4
gi|189491769 thyroid hormone receptor, beta [Homo sapiens] 28 8.4
gi|40806162 thyroid hormone receptor, beta [Homo sapiens] 28 8.4
>gi|10835145 interleukin 1, beta proprotein [Homo sapiens]
Length = 269
Score = 550 bits (1416), Expect = e-157
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKG 60
MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKG
Sbjct: 1 MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKG 60
Query: 61 FRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVR 120
FRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVR
Sbjct: 61 FRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVR 120
Query: 121 SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKE 180
SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKE
Sbjct: 121 SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKE 180
Query: 181 KNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYIST 240
KNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYIST
Sbjct: 181 KNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYIST 240
Query: 241 SQAENMPVFLGGTKGGQDITDFTMQFVSS 269
SQAENMPVFLGGTKGGQDITDFTMQFVSS
Sbjct: 241 SQAENMPVFLGGTKGGQDITDFTMQFVSS 269
>gi|27894313 interleukin 1 family, member 8 isoform 2 [Homo sapiens]
Length = 157
Score = 61.2 bits (147), Expect = 9e-10
Identities = 46/146 (31%), Positives = 74/146 (50%), Gaps = 7/146 (4%)
Query: 126 LRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIP---VALGLKEKN 182
+RDS+Q V+SG + A + + V + + E +DK V LG+K K+
Sbjct: 14 IRDSRQMVWVLSGNSLIAAPLSRSI---KPVTLHLIACRDTEFSDKEKGNMVYLGIKGKD 70
Query: 183 LYLSCVLKDDKPTLQLESVDPKN-YPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTS 241
L L C KPTLQL+ + + Y +KK +K F+F + + F+S +P W+I+TS
Sbjct: 71 LCLFCAEIQGKPTLQLKEKNIMDLYVEKKAQKPFLFFHNKEGSTSVFQSVSYPGWFIATS 130
Query: 242 QAENMPVFLGGTKGGQDITDFTMQFV 267
P+FL +G + T+F + V
Sbjct: 131 TTSGQPIFLTKERGITNNTNFYLDSV 156
>gi|7657092 interleukin 1 family, member 6 (epsilon) [Homo sapiens]
Length = 158
Score = 58.5 bits (140), Expect = 6e-09
Identities = 39/113 (34%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 157 VFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKN-YPKKKMEKRF 215
+ S V+ E + P+ LGL NL L C D+PTLQL+ D + Y + + K F
Sbjct: 46 LISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSF 105
Query: 216 VFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDF--TMQF 266
+F + FES FP W+I+ S P+ L G + TDF TM F
Sbjct: 106 LFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF 158
>gi|27894321 interleukin 1 receptor antagonist isoform 4 [Homo
sapiens]
Length = 143
Score = 52.8 bits (125), Expect = 3e-07
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 166 EESNDKIPVA-----LGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPK-KKMEKRFVFNK 219
EE D +P+ LG+ + LSCV D+ LQLE+V+ + + +K +KRF F +
Sbjct: 34 EEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIR 93
Query: 220 IEINNKLEFESAQFPNWYISTSQAENMPVFL 250
+ FESA P W++ T+ + PV L
Sbjct: 94 SDSGPTTSFESAACPGWFLCTAMEADQPVSL 124
>gi|27894319 interleukin 1 receptor antagonist isoform 1 precursor
[Homo sapiens]
Length = 177
Score = 52.8 bits (125), Expect = 3e-07
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 166 EESNDKIPVA-----LGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPK-KKMEKRFVFNK 219
EE D +P+ LG+ + LSCV D+ LQLE+V+ + + +K +KRF F +
Sbjct: 68 EEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIR 127
Query: 220 IEINNKLEFESAQFPNWYISTSQAENMPVFL 250
+ FESA P W++ T+ + PV L
Sbjct: 128 SDSGPTTSFESAACPGWFLCTAMEADQPVSL 158
>gi|27894317 interleukin 1 receptor antagonist isoform 2 [Homo
sapiens]
Length = 180
Score = 52.8 bits (125), Expect = 3e-07
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 166 EESNDKIPVA-----LGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPK-KKMEKRFVFNK 219
EE D +P+ LG+ + LSCV D+ LQLE+V+ + + +K +KRF F +
Sbjct: 71 EEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIR 130
Query: 220 IEINNKLEFESAQFPNWYISTSQAENMPVFL 250
+ FESA P W++ T+ + PV L
Sbjct: 131 SDSGPTTSFESAACPGWFLCTAMEADQPVSL 161
>gi|10835147 interleukin 1 receptor antagonist isoform 3 [Homo
sapiens]
Length = 159
Score = 52.8 bits (125), Expect = 3e-07
Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 166 EESNDKIPVA-----LGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPK-KKMEKRFVFNK 219
EE D +P+ LG+ + LSCV D+ LQLE+V+ + + +K +KRF F +
Sbjct: 50 EEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIR 109
Query: 220 IEINNKLEFESAQFPNWYISTSQAENMPVFL 250
+ FESA P W++ T+ + PV L
Sbjct: 110 SDSGPTTSFESAACPGWFLCTAMEADQPVSL 140
>gi|27894330 interleukin 1, alpha proprotein [Homo sapiens]
Length = 271
Score = 47.4 bits (111), Expect = 1e-05
Identities = 69/275 (25%), Positives = 115/275 (41%), Gaps = 24/275 (8%)
Query: 1 MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPL-----DGGIQLRISDH 55
MA+VP++ ++ YS NE+D D + SF + PL D + L IS+
Sbjct: 1 MAKVPDMFEDLKNCYSENEED-SSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISET 59
Query: 56 HYSK--GFRQAASVVVAMDK-LRKMLVPCPQTFQENDLSTFF----PFIFEEEPIFFDTW 108
+ F+++ VV K L+K + Q+ ++DL I + F
Sbjct: 60 SKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFL 119
Query: 109 DNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEES 168
N Y + + L D+ +S++ + L A L ++++ V F M + +
Sbjct: 120 SNVKY-NFMRIIKYEFILNDALNQSIIRANDQYLTAAAL--HNLDEAVKFDMGAYKSSKD 176
Query: 169 NDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVD-PKNYPKKKMEKRFVFNKIEINNKLE 227
+ KI V L + + LY++ +D+P L E + PK + F + N
Sbjct: 177 DAKITVILRISKTQLYVT-AQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKN--Y 233
Query: 228 FESAQFPNWYISTSQAENMPVFLGGTKGGQDITDF 262
F S PN +I+T Q + V L G G ITDF
Sbjct: 234 FTSVAHPNLFIATKQ--DYWVCLAG--GPPSITDF 264
>gi|27894310 interleukin 1 family, member 5 [Homo sapiens]
Length = 155
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 15/138 (10%)
Query: 142 LKALHLQGQDMEQQVVFSMSFVQGEESN---------DKIPVALGLKEKNLYLSCVLKDD 192
LK L+L + + + ++GEE + PV LG++ + LSC + +
Sbjct: 16 LKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSCGVGQE 75
Query: 193 KPTLQLESVDPKN-YPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLG 251
PTL LE V+ Y K K F F + ++ FESA +P W++ T + PV L
Sbjct: 76 -PTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLT 134
Query: 252 --GTKGGQD--ITDFTMQ 265
GG + ITDF Q
Sbjct: 135 QLPENGGWNAPITDFYFQ 152
>gi|6912432 interleukin 1 family, member 5 [Homo sapiens]
Length = 155
Score = 46.2 bits (108), Expect = 3e-05
Identities = 42/138 (30%), Positives = 63/138 (45%), Gaps = 15/138 (10%)
Query: 142 LKALHLQGQDMEQQVVFSMSFVQGEESN---------DKIPVALGLKEKNLYLSCVLKDD 192
LK L+L + + + ++GEE + PV LG++ + LSC + +
Sbjct: 16 LKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSCGVGQE 75
Query: 193 KPTLQLESVDPKN-YPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLG 251
PTL LE V+ Y K K F F + ++ FESA +P W++ T + PV L
Sbjct: 76 -PTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLT 134
Query: 252 --GTKGGQD--ITDFTMQ 265
GG + ITDF Q
Sbjct: 135 QLPENGGWNAPITDFYFQ 152
>gi|9665234 interleukin 1 family, member 9 [Homo sapiens]
Length = 169
Score = 45.8 bits (107), Expect = 4e-05
Identities = 33/152 (21%), Positives = 65/152 (42%), Gaps = 2/152 (1%)
Query: 114 VHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIP 173
V+ + + + T+ D Q+ + G + V + + + E P
Sbjct: 15 VYQSMCKPITGTINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVITCKYPEALEQGRGDP 74
Query: 174 VALGLKEKNLYLSCVLKDDKPTLQLESVDPKN-YPKKKMEKRFVFNKIEINNKLEFESAQ 232
+ LG++ + L C ++PTLQL+ + Y + + K F+F + + ES
Sbjct: 75 IYLGIQNPEMCLYCEKVGEQPTLQLKEQKIMDLYGQPEPVKPFLFYRAKTGRTSTLESVA 134
Query: 233 FPNWYISTSQAENMPVFLGGTKGGQDITDFTM 264
FP+W+I++S+ + P+ L G T F +
Sbjct: 135 FPDWFIASSK-RDQPIILTSELGKSYNTAFEL 165
>gi|27894307 interleukin 1 family, member 10 [Homo sapiens]
Length = 152
Score = 44.3 bits (103), Expect = 1e-04
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 171 KIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKN-YPKKKMEKRFVFNKIEINNKLEFE 229
K+P+ LG++ + L+CV ++ P+LQLE V+ + Y + RF F + + E
Sbjct: 54 KVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLE 113
Query: 230 SAQFPNWYISTSQAENMPVFL 250
+A +P W++ PV L
Sbjct: 114 AAAWPGWFLCGPAEPQQPVQL 134
>gi|27894304 interleukin 1 family, member 10 [Homo sapiens]
Length = 152
Score = 44.3 bits (103), Expect = 1e-04
Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 171 KIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKN-YPKKKMEKRFVFNKIEINNKLEFE 229
K+P+ LG++ + L+CV ++ P+LQLE V+ + Y + RF F + + E
Sbjct: 54 KVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLE 113
Query: 230 SAQFPNWYISTSQAENMPVFL 250
+A +P W++ PV L
Sbjct: 114 AAAWPGWFLCGPAEPQQPVQL 134
>gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein
[Homo sapiens]
Length = 218
Score = 38.5 bits (88), Expect = 0.006
Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 13/146 (8%)
Query: 113 YVHDAP-VRSLN---CTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEES 168
+VH +P V++LN ++ D K LV+ L A+ + + ++ F+++ S
Sbjct: 45 FVHTSPKVKNLNPKKFSIHDQDHKVLVLDSG-NLIAVPDKNY-IRPEIFFALASSLSSAS 102
Query: 169 NDK-IPVALGLKEKNLYLSCVLKD---DKPTLQL--ESVDPKNYPKKKMEKRFVFNKIEI 222
+K P+ LG+ + L C KD P+LQL E + K+ + F+F + ++
Sbjct: 103 AEKGSPILLGVSKGEFCLYCD-KDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQV 161
Query: 223 NNKLEFESAQFPNWYISTSQAENMPV 248
+ ESA P W+I TS N PV
Sbjct: 162 GSWNMLESAAHPGWFICTSCNCNEPV 187
>gi|27894298 interleukin 1 family, member 7 isoform 3 [Homo sapiens]
Length = 157
Score = 36.6 bits (83), Expect = 0.024
Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 154 QQVVFSMSFVQGEESNDK-IPVALGLKEKNLYLSCVLKD---DKPTLQL--ESVDPKNYP 207
+++ F+++ S +K P+ LG+ + L C KD P+LQL E +
Sbjct: 27 EEIFFALASSLSSASAEKGSPILLGVSKGEFCLYCD-KDKGQSHPSLQLKKEKLMKLAAQ 85
Query: 208 KKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPV 248
K+ + F+F + ++ + ESA P W+I TS N PV
Sbjct: 86 KESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPV 126
>gi|27894296 interleukin 1 family, member 7 isoform 2 [Homo sapiens]
Length = 197
Score = 35.8 bits (81), Expect = 0.040
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 155 QVVFSMSFVQGEESNDK-IPVALGLKEKNLYLSCVLKD---DKPTLQL--ESVDPKNYPK 208
++ F+++ S +K P+ LG+ + L C KD P+LQL E + K
Sbjct: 68 EIFFALASSLSSASAEKGSPILLGVSKGEFCLYCD-KDKGQSHPSLQLKKEKLMKLAAQK 126
Query: 209 KKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPV 248
+ + F+F + ++ + ESA P W+I TS N PV
Sbjct: 127 ESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPV 166
>gi|27894302 interleukin 1 family, member 7 isoform 5 [Homo sapiens]
Length = 192
Score = 35.8 bits (81), Expect = 0.040
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 155 QVVFSMSFVQGEESNDK-IPVALGLKEKNLYLSCVLKD---DKPTLQL--ESVDPKNYPK 208
++ F+++ S +K P+ LG+ + L C KD P+LQL E + K
Sbjct: 63 EIFFALASSLSSASAEKGSPILLGVSKGEFCLYCD-KDKGQSHPSLQLKKEKLMKLAAQK 121
Query: 209 KKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPV 248
+ + F+F + ++ + ESA P W+I TS N PV
Sbjct: 122 ESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPV 161
>gi|27894300 interleukin 1 family, member 7 isoform 4 [Homo sapiens]
Length = 178
Score = 35.4 bits (80), Expect = 0.053
Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 159 SMSFVQGEESNDKIPVALGLKEKNLYLSCVLKD---DKPTLQL--ESVDPKNYPKKKMEK 213
S+S E+ + P+ LG+ + L C KD P+LQL E + K+ +
Sbjct: 57 SLSSASAEKGS---PILLGVSKGEFCLYCD-KDKGQSHPSLQLKKEKLMKLAAQKESARR 112
Query: 214 RFVFNKIEINNKLEFESAQFPNWYISTSQAENMPV 248
F+F + ++ + ESA P W+I TS N PV
Sbjct: 113 PFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPV 147
>gi|31657117 SMEK homolog 1, suppressor of mek1 [Homo sapiens]
Length = 820
Score = 30.0 bits (66), Expect = 2.2
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 52 ISDHHYSKGFRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIF 98
ISD + Q V D M++P P F+EN LST FIF
Sbjct: 252 ISDPELKQKIHQTYRVQYIQD----MVLPTPSVFEENMLSTLHSFIF 294
>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
Length = 791
Score = 29.6 bits (65), Expect = 2.9
Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 121 SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESN---DKIPVALG 177
S++ L++ QQ+S+V + E +++H G+ Q+ + + ESN K +
Sbjct: 199 SIDHDLKNLQQQSVVCNN--EAESIHCDGEGSNNQIDIADDIINASESNRDCSKPVASTN 256
Query: 178 LKEKNLYLSCVLKDDKPT 195
L + + CV ++++ T
Sbjct: 257 LDNEAMQQDCVFENEENT 274
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 29.6 bits (65), Expect = 2.9
Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 121 SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESN---DKIPVALG 177
S++ L++ QQ+S+V + E +++H G+ Q+ + + ESN K +
Sbjct: 317 SIDHDLKNLQQQSVVCNN--EAESIHCDGEGSNNQIDIADDIINASESNRDCSKPVASTN 374
Query: 178 LKEKNLYLSCVLKDDKPT 195
L + + CV ++++ T
Sbjct: 375 LDNEAMQQDCVFENEENT 392
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 29.6 bits (65), Expect = 2.9
Identities = 18/78 (23%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 121 SLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESN---DKIPVALG 177
S++ L++ QQ+S+V + E +++H G+ Q+ + + ESN K +
Sbjct: 317 SIDHDLKNLQQQSVVCNN--EAESIHCDGEGSNNQIDIADDIINASESNRDCSKPVASTN 374
Query: 178 LKEKNLYLSCVLKDDKPT 195
L + + CV ++++ T
Sbjct: 375 LDNEAMQQDCVFENEENT 392
>gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo sapiens]
Length = 164
Score = 29.3 bits (64), Expect = 3.8
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 6/77 (7%)
Query: 126 LRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIP---VALGLKEKN 182
+RDS+Q V+SG + A + + V + + E +DK V LG+K K+
Sbjct: 14 IRDSRQMVWVLSGNSLIAAPLSRSI---KPVTLHLIACRDTEFSDKEKGNMVYLGIKGKD 70
Query: 183 LYLSCVLKDDKPTLQLE 199
L L C KPTLQL+
Sbjct: 71 LCLFCAEIQGKPTLQLK 87
>gi|39930397 SMEK homolog 2, suppressor of mek1 isoform 2 [Homo
sapiens]
Length = 764
Score = 28.9 bits (63), Expect = 4.9
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 62 RQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIF 98
RQ + ++ +++P P F+EN LST FIF
Sbjct: 260 RQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIF 296
>gi|171916095 SMEK homolog 2, suppressor of mek1 isoform 1 [Homo
sapiens]
Length = 849
Score = 28.9 bits (63), Expect = 4.9
Identities = 13/37 (35%), Positives = 20/37 (54%)
Query: 62 RQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIF 98
RQ + ++ +++P P F+EN LST FIF
Sbjct: 260 RQKIHQTYRVQYIQDIILPTPSVFEENFLSTLTSFIF 296
>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 28.1 bits (61), Expect = 8.4
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 110 NEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESN 169
+EA +H TL++ Q ++ + HL D+ Q V S Q EE
Sbjct: 33 SEACLHRKSHSERRSTLKNEQSSPHLIQTTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKK 92
Query: 170 DKIPVALGLKEKNLYLSCVLKDDKPT 195
K + L + L CV+ DK T
Sbjct: 93 CKGYIPSYLDKDEL---CVVCGDKAT 115
>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 28.1 bits (61), Expect = 8.4
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 110 NEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESN 169
+EA +H TL++ Q ++ + HL D+ Q V S Q EE
Sbjct: 33 SEACLHRKSHSERRSTLKNEQSSPHLIQTTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKK 92
Query: 170 DKIPVALGLKEKNLYLSCVLKDDKPT 195
K + L + L CV+ DK T
Sbjct: 93 CKGYIPSYLDKDEL---CVVCGDKAT 115
>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
Length = 461
Score = 28.1 bits (61), Expect = 8.4
Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 3/86 (3%)
Query: 110 NEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESN 169
+EA +H TL++ Q ++ + HL D+ Q V S Q EE
Sbjct: 33 SEACLHRKSHSERRSTLKNEQSSPHLIQTTWTSSIFHLDHDDVNDQSVSSAQTFQTEEKK 92
Query: 170 DKIPVALGLKEKNLYLSCVLKDDKPT 195
K + L + L CV+ DK T
Sbjct: 93 CKGYIPSYLDKDEL---CVVCGDKAT 115
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,044,604
Number of Sequences: 37866
Number of extensions: 434025
Number of successful extensions: 938
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 906
Number of HSP's gapped (non-prelim): 30
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.