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Search of human proteins with 239748674
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens] 687 0.0
gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens] 687 0.0
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 46 4e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 46 6e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 46 6e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 46 6e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 46 6e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 46 6e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 46 6e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 46 6e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 46 6e-05
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 44 2e-04
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 43 5e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 43 5e-04
gi|45439327 periplakin [Homo sapiens] 42 6e-04
gi|32698688 citron [Homo sapiens] 42 8e-04
gi|221139761 zinc finger protein 853 [Homo sapiens] 42 0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 0.001
gi|148746195 trichohyalin [Homo sapiens] 42 0.001
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 41 0.002
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.002
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 40 0.004
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.004
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 40 0.004
gi|16262452 cingulin [Homo sapiens] 40 0.004
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 39 0.005
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 39 0.007
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 39 0.007
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 39 0.007
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 39 0.007
>gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens]
Length = 348
Score = 687 bits (1774), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60
MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE
Sbjct: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60
Query: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120
VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD
Sbjct: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120
Query: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180
CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV
Sbjct: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180
Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240
EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE
Sbjct: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240
Query: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300
QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ
Sbjct: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300
Query: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD
Sbjct: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
>gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens]
Length = 348
Score = 687 bits (1774), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60
MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE
Sbjct: 1 MLFEEALPLSCSDPVLSTLSLVQFSPSGRTQDLLSPGVENLSVLDVSPLGLVVEDATEVE 60
Query: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120
VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD
Sbjct: 61 VSDSKAASELYLQATAGEGRACCLLTLTMSCPGPDPPEGPGTQRVWQGALRILQLPGAPD 120
Query: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180
CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV
Sbjct: 121 CPLLRVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAV 180
Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240
EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE
Sbjct: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240
Query: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300
QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ
Sbjct: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300
Query: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD
Sbjct: 301 ATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 46.2 bits (108), Expect = 4e-05
Identities = 56/179 (31%), Positives = 82/179 (45%), Gaps = 27/179 (15%)
Query: 172 VRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIW 231
+R L D+ E RA L+ LR TD + A RE+ QRLR +++
Sbjct: 552 LRKQLSDSESERRALEEQLQRLR------DKTDGAMQAHEDAQREV----QRLRSANELL 601
Query: 232 IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDL 291
REK +L +VA Q EE +ER++ Q Q LR Q + L+EE+ A QD
Sbjct: 602 SREK-SNLAHSLQVAQQQA------EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDG 654
Query: 292 AALYDLHVQATRAQTHHVL-PISGDGGLLAGTL---EETINLAT-QNQELQAENQQLQQ 345
A V+ ++H L + G +LA L E ++ AT Q LQAE ++ +
Sbjct: 655 A-----RVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAE 708
Score = 36.2 bits (82), Expect = 0.045
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 14/180 (7%)
Query: 179 AVEEARARRAGLRPL--RLGLLEDTLTDSGLSQLGRALRELEAQ------RQRLREQHQI 230
++ + RA A L+ +L L ++L L L R + +LE + RQR EQ
Sbjct: 723 SMTKLRAEEASLQDSLSKLSALNESLAQDKLD-LNRLVAQLEEEKSALQGRQRQAEQEAT 781
Query: 231 WIREKLKHLEQ---KEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTA 287
RE+ + LE+ ++EVA ++G + E +E +Q+ LR + LQE+
Sbjct: 782 VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQE--ALEQQLPTLRHERSQLQEQLAQL 839
Query: 288 EQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGA 347
+ L+ QA R V + +E LA Q + E + L + A
Sbjct: 840 SRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEA 899
Score = 34.7 bits (78), Expect = 0.13
Identities = 46/170 (27%), Positives = 68/170 (40%), Gaps = 17/170 (10%)
Query: 180 VEEARARRAGLRPLRLGLLEDTLTDSGLSQLGR----ALRELEAQRQRLREQHQIWIREK 235
V+ R +A LR R ED L +L R A RELEA+R +L+ Q Q E
Sbjct: 974 VQAEREAQASLREQRAAHEED------LQRLQREKEAAWRELEAERAQLQSQLQREQEEL 1027
Query: 236 LKHLEQKEEVADDQVKGLVAE--EEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAA 293
L LE ++E +++ L E E QQ + + AL E+ LA
Sbjct: 1028 LARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLAT 1087
Query: 294 L-YDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQ 342
+ ++ Q AQ+ D + E +L Q +E A + Q
Sbjct: 1088 ISLEMERQKRDAQSRQ----EQDRSTVNALTSELRDLRAQREEAAAAHAQ 1133
Score = 33.5 bits (75), Expect = 0.29
Identities = 39/139 (28%), Positives = 61/139 (43%), Gaps = 9/139 (6%)
Query: 207 LSQLGRAL--RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQ 264
L+QL R L RE E ++ R Q Q+ E L+ +++E + GL + A E
Sbjct: 836 LAQLSRQLSGREQELEQARREAQRQV---EALERAAREKEALAKEHAGLAVQLVAAEREG 892
Query: 265 RWQQEQMV-LRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTL 323
R E+ LR + EAL+ ++ LA L Q +L G LAG
Sbjct: 893 RTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLR 952
Query: 324 EETI---NLATQNQELQAE 339
++ I A+ ++EL A+
Sbjct: 953 QQIIATQEKASLDKELMAQ 971
Score = 30.0 bits (66), Expect = 3.2
Identities = 37/176 (21%), Positives = 76/176 (43%), Gaps = 28/176 (15%)
Query: 157 LLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216
L R++ +G+ Q+++V + A L ++ E L L L RAL +
Sbjct: 1803 LQRVEAEGQLQQLREVLR------QRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQ 1856
Query: 217 LEAQRQRLR------EQHQIWIREKLKHLEQKEEVADDQVKGLVAEE------------- 257
LEA+++ + E+ ++ +R L +E+++ + + L AE+
Sbjct: 1857 LEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELE 1916
Query: 258 --EACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDL-HVQATRAQTHHVL 310
EA + Q+ + + +VL Q E + +Q L ++ +++ +AQT L
Sbjct: 1917 LAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTL 1972
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1915 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1970
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1971 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2021
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2069
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2070 QQEQSVLD 2077
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1625 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1680
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1681 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1800 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1830
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1445
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1446 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAAR 1529
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1553 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1606
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1607 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1712
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1713 QELIRLRAETEQGEQ 1727
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2530 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2586
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2587 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2646
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2647 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2706
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2707 NEKLSVYAALQRQLL 2721
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQA 2127
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1924
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRI 1951
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 1976 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2088
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2089 AAEEAEEARVQAER 2102
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2211 RLKAEATEAARQRS 2224
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2254 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2308
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2309 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2368
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2369 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2422
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAE 2446
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1919 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1974
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1975 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2025
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2026 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2073
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2074 QQEQSVLD 2081
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1629 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1684
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1685 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1743
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1744 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1803
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1804 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1834
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1399 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1449
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1450 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1509
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1510 ESQRKRQAEVELASRVKAEAEAAR 1533
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1557 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1610
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1611 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1656
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1657 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1716
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1717 QELIRLRAETEQGEQ 1731
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2534 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2590
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2591 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2650
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2651 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2710
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2711 NEKLSVYAALQRQLL 2725
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 1987 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2046
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2106
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2107 EAAQSRRQVEEAERLKQSAEEQAQA 2131
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1871 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1928
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1929 EEILALKASFEKAAAGKAELELELGRI 1955
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 1980 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2036
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2037 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2092
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2093 AAEEAEEARVQAER 2106
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2095 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2154
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2155 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2214
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2215 RLKAEATEAARQRS 2228
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2258 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2312
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2313 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2372
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2373 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2426
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2427 ATQEKVTLVQTLEIQRQQSDHDAE 2450
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1915 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1970
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1971 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2021
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2022 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2069
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2070 QQEQSVLD 2077
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1625 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1680
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1681 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1740 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1800 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1830
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1445
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1446 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAAR 1529
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1553 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1606
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1607 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1652
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1712
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1713 QELIRLRAETEQGEQ 1727
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2530 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2586
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2587 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2646
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2647 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2706
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2707 NEKLSVYAALQRQLL 2721
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2042
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2103 EAAQSRRQVEEAERLKQSAEEQAQA 2127
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1924
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1925 EEILALKASFEKAAAGKAELELELGRI 1951
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 1976 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2032
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2033 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2088
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2089 AAEEAEEARVQAER 2102
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2091 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2150
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2151 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2210
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2211 RLKAEATEAARQRS 2224
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2254 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2308
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2309 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2368
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2369 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2422
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAE 2446
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1883 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1938
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1939 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 1989
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 1990 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2037
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2038 QQEQSVLD 2045
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1593 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1648
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1649 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1707
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1708 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1767
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1768 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1798
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1363 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1413
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1414 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1473
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1474 ESQRKRQAEVELASRVKAEAEAAR 1497
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1521 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1574
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1575 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1620
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1621 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1680
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1681 QELIRLRAETEQGEQ 1695
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2498 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2554
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2555 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2614
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2615 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2674
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2675 NEKLSVYAALQRQLL 2689
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 1951 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2010
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2070
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2071 EAAQSRRQVEEAERLKQSAEEQAQA 2095
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1835 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1892
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1893 EEILALKASFEKAAAGKAELELELGRI 1919
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 1944 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2000
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2001 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2056
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2057 AAEEAEEARVQAER 2070
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2059 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2118
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2119 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2178
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2179 RLKAEATEAARQRS 2192
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2222 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2276
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2277 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2336
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2337 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2390
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2391 ATQEKVTLVQTLEIQRQQSDHDAE 2414
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 2052 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 2107
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 2108 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2158
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2159 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2206
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2207 QQEQSVLD 2214
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1762 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1817
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1818 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1876
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1877 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1936
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1937 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1967
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1532 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1582
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1583 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1642
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1643 ESQRKRQAEVELASRVKAEAEAAR 1666
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1690 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1743
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1744 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1789
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1790 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1849
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1850 QELIRLRAETEQGEQ 1864
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2667 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2723
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2724 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2783
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2784 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2843
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2844 NEKLSVYAALQRQLL 2858
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2179
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2239
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2240 EAAQSRRQVEEAERLKQSAEEQAQA 2264
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 2004 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 2061
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 2062 EEILALKASFEKAAAGKAELELELGRI 2088
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 2113 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2169
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2170 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2225
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2226 AAEEAEEARVQAER 2239
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2228 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2287
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2288 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2347
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2348 RLKAEATEAARQRS 2361
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2391 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2445
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2446 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2505
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2506 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2559
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2560 ATQEKVTLVQTLEIQRQQSDHDAE 2583
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1893 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1948
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1949 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 1999
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2000 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2047
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2048 QQEQSVLD 2055
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1603 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1658
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1659 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1717
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1718 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1777
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1778 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1808
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1373 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1423
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1424 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1483
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1484 ESQRKRQAEVELASRVKAEAEAAR 1507
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1531 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1584
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1585 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1630
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1631 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1690
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1691 QELIRLRAETEQGEQ 1705
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2508 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2564
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2565 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2624
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2625 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2684
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2685 NEKLSVYAALQRQLL 2699
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 1961 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2020
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2080
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2081 EAAQSRRQVEEAERLKQSAEEQAQA 2105
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1845 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1902
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1903 EEILALKASFEKAAAGKAELELELGRI 1929
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 1954 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2010
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2011 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2066
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2067 AAEEAEEARVQAER 2080
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2069 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2128
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2129 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2188
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2189 RLKAEATEAARQRS 2202
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2232 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2286
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2287 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2346
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2347 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2400
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2401 ATQEKVTLVQTLEIQRQQSDHDAE 2424
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1901 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1956
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1957 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2007
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2008 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2055
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2056 QQEQSVLD 2063
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1611 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1666
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1667 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1725
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1726 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1785
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1786 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1816
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1381 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1431
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1432 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1491
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1492 ESQRKRQAEVELASRVKAEAEAAR 1515
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1539 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1592
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1593 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1638
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1639 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1698
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1699 QELIRLRAETEQGEQ 1713
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2516 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2572
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2573 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2632
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2633 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2692
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2693 NEKLSVYAALQRQLL 2707
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 1969 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2028
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2088
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2089 EAAQSRRQVEEAERLKQSAEEQAQA 2113
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1853 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1910
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1911 EEILALKASFEKAAAGKAELELELGRI 1937
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 1962 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2018
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2019 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2074
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2075 AAEEAEEARVQAER 2088
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2077 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2136
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2137 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2196
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2197 RLKAEATEAARQRS 2210
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2240 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2294
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2295 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2354
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2355 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2408
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2409 ATQEKVTLVQTLEIQRQQSDHDAE 2432
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/188 (29%), Positives = 81/188 (43%), Gaps = 25/188 (13%)
Query: 161 DPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ 220
D +R QV++ L + E+A A +A L L LG + D+ S + ELEA
Sbjct: 1942 DTLRQRRQVEEEILALKASFEKAAAGKAELE-LELGRIRSNAEDTLRS---KEQAELEAA 1997
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
RQR Q+ E+ + E +E V K L AEEEA +R+ +E L+ ++E
Sbjct: 1998 RQR-----QLAAEEERRRREAEERVQ----KSLAAEEEAARQRKAALEEVERLKAKVEEA 2048
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAEN 340
+ R AEQ+ A L +A + + L A + + QELQ
Sbjct: 2049 RRLRERAEQESARQLQLAQEAAQKR------------LQAEEKAHAFAVQQKEQELQQTL 2096
Query: 341 QQLQQGAD 348
QQ Q D
Sbjct: 2097 QQEQSVLD 2104
Score = 45.4 bits (106), Expect = 7e-05
Identities = 50/216 (23%), Positives = 91/216 (42%), Gaps = 11/216 (5%)
Query: 134 EEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPL 193
EEAE L W L+ N L L+ + ++ + Q E ARR G +
Sbjct: 1652 EEAERELE---RWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRG-KAE 1707
Query: 194 RLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGL 253
+ + L + L + R L E AQ++ EQ I +R + + EQ+ ++ ++++ L
Sbjct: 1708 EQAVRQRELAEQELEKQ-RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1766
Query: 254 VAEEEAC-EERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
E A ++RQ + E +R ++E L + AE++ + + Q A+ +
Sbjct: 1767 QREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1826
Query: 313 SGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ + L EE + Q AE +Q A+
Sbjct: 1827 AEEAARLRALAEE-----AKRQRQLAEEDAARQRAE 1857
Score = 40.0 bits (92), Expect = 0.003
Identities = 40/144 (27%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 165 RRMQVKQVR--PTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA-QR 221
+RMQ + VR DA ++ R+ + L+ LR S +++ R+ EA +R
Sbjct: 1422 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLR---------QSSEAEIQAKARQAEAAER 1472
Query: 222 QRLREQHQIWI-REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEA 279
RLR + +I + R +L+ E++ A+ +++ L A E E ++R QE+ LR Q++
Sbjct: 1473 SRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1532
Query: 280 LQEERNTAEQDLAALYDLHVQATR 303
+ + AE +LA+ +A R
Sbjct: 1533 ESQRKRQAEVELASRVKAEAEAAR 1556
Score = 36.6 bits (83), Expect = 0.034
Identities = 46/195 (23%), Positives = 76/195 (38%), Gaps = 34/195 (17%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
R+ +V++ R R+ A L+ R E T +QL R+L+E +L
Sbjct: 1580 RQAEVERARQVQVALETAQRSAEAELQSKRASFAEKT------AQLERSLQEEHVAVAQL 1633
Query: 225 REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ---QEQMVLRFQLEAL- 280
RE+ E A Q + A EEA E +RWQ E + LR Q E +
Sbjct: 1634 REE--------------AERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVA 1679
Query: 281 ----------QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
++++ AE++ QA R + + L GT ++ +
Sbjct: 1680 QQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAE 1739
Query: 331 TQNQELQAENQQLQQ 345
+ L+AE +Q +Q
Sbjct: 1740 QELIRLRAETEQGEQ 1754
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/195 (27%), Positives = 76/195 (38%), Gaps = 19/195 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q ++ Q++Q R L ++EEAR R+ G+ L Q R EL
Sbjct: 2557 LREEQQRQQQQMEQERQRLVASMEEARRRQ---HEAEEGVRRKQEELQQLEQQRRQQEEL 2613
Query: 218 EAQR-QRLREQHQIWIREKLKHLEQKEEVADDQVKGL--------VAEEEACEERQRWQQ 268
A+ QRLREQ Q+ + L EEV QV + A E
Sbjct: 2614 LAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSF 2673
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQ----ATRAQTHHVLP-ISGDGGLLAGTL 323
+ + + + LQE + ++L L H A R H L S GLL
Sbjct: 2674 DGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKAT 2733
Query: 324 EETINL--ATQNQEL 336
E +++ A Q Q L
Sbjct: 2734 NEKLSVYAALQRQLL 2748
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 16/145 (11%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLR--------LGLLEDTLTDSGLSQLGRALRE 216
RR ++V+ +L E AR R+A L + L + QL A
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEA 2069
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQ---KEEVADDQVKGLV-----AEEEACEERQRWQQ 268
+ + Q + H +++K + L+Q +E+ DQ++G A EEA E R + ++
Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2129
Query: 269 EQMVLRFQLEALQEERNTAEQDLAA 293
E R Q+E + + +AE+ A
Sbjct: 2130 EAAQSRRQVEEAERLKQSAEEQAQA 2154
Score = 33.9 bits (76), Expect = 0.22
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 212 RALRELEA-QRQRLREQ---HQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
R L E EA QR+RL EQ H+ I E+L L + + ++ KGLV E+ +R++ +
Sbjct: 1894 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLV--EDTLRQRRQVE 1951
Query: 268 QEQMVLRFQLEALQEERNTAEQDLAAL 294
+E + L+ E + E +L +
Sbjct: 1952 EEILALKASFEKAAAGKAELELELGRI 1978
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 16/134 (11%)
Query: 179 AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKH 238
A EE R RR ++ L + + Q AL E+E + ++ E ++ R + +
Sbjct: 2003 AAEEERRRREAEERVQKSLAAE---EEAARQRKAALEEVERLKAKVEEARRLRERAEQES 2059
Query: 239 LEQKEEVADDQVKGLVAEEEAC---------EERQRWQQEQMVLRFQLEALQEERNTAEQ 289
Q + + K L AEE+A E +Q QQEQ V L+ L+ E A +
Sbjct: 2060 ARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQLRGEAEAARR 2115
Query: 290 DLAALYDLHVQATR 303
+ VQA R
Sbjct: 2116 AAEEAEEARVQAER 2129
Score = 32.3 bits (72), Expect = 0.65
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 5/134 (3%)
Query: 178 DAVEEAR--ARRAGLRPLRLGLLEDTLTDSGLSQL-GRALRELEAQRQRLREQHQIWIRE 234
+ EEAR A R + R + L S Q RA + A++ R + + R
Sbjct: 2118 EEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRA 2177
Query: 235 KLKH--LEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLA 292
+ + L QK+ + K E+ ++ + +QE LR QLE ++N +++L
Sbjct: 2178 QAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQ 2237
Query: 293 ALYDLHVQATRAQT 306
L +A R ++
Sbjct: 2238 RLKAEATEAARQRS 2251
Score = 30.0 bits (66), Expect = 3.2
Identities = 51/204 (25%), Positives = 80/204 (39%), Gaps = 22/204 (10%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALR 215
L+LR +R ++ A E AR A RL L + L+Q RAL
Sbjct: 2281 LILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLR----QLAEEDLAQQ-RALA 2335
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE-----ACEERQRWQ--- 267
E + + Q ++ + + L+Q++E+A +Q + L ++E EE Q +Q
Sbjct: 2336 EKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTL 2395
Query: 268 --QEQMVLRFQLEALQEERNTAEQDLA-ALYDLHVQATRAQTHHVLPISGDGGLLAGTLE 324
+ Q L EA + + AE A A + Q R Q + G L T
Sbjct: 2396 EAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEI------GEKLHRTEL 2449
Query: 325 ETINLATQNQELQAENQQLQQGAD 348
T T Q L+ + QQ A+
Sbjct: 2450 ATQEKVTLVQTLEIQRQQSDHDAE 2473
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 44.3 bits (103), Expect = 2e-04
Identities = 39/168 (23%), Positives = 76/168 (45%), Gaps = 27/168 (16%)
Query: 147 LLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSG 206
L E + LL+ + + RR Q ++++ L + EA RA ++ E L +
Sbjct: 367 LQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQA------EMELKEEE 420
Query: 207 LSQLGRALRELEAQRQRLREQHQIWIR--------------------EKLKHLEQKEEVA 246
++ + ++ELE +QRL+E Q+ ++ EKLK L Q +E
Sbjct: 421 AARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQ 480
Query: 247 DDQVKGLVAEEEACEERQRWQQEQMV-LRFQLEALQEERNTAEQDLAA 293
+ ++ E+E ++ Q + + QLE +++ R A++D+ A
Sbjct: 481 ERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEA 528
Score = 34.7 bits (78), Expect = 0.13
Identities = 43/204 (21%), Positives = 85/204 (41%), Gaps = 23/204 (11%)
Query: 161 DPQGRRMQ--VKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELE 218
D G+R VK T + + R R+ +++ + L G + L + L++
Sbjct: 273 DRDGKRCMFCVKTANRTYEMSASDTRQRQEWTAAIQMAI---RLQAEGKTSLHKDLKQKR 329
Query: 219 AQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA--------CEERQRWQQEQ 270
+++ RE+ + E+L L+Q +E + +++ L +EA EE +R + +
Sbjct: 330 REQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQH 389
Query: 271 MVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTL------- 323
L+ LE E A + A +L + Q + + L L
Sbjct: 390 RELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKAR 449
Query: 324 --EETINLATQNQELQAENQQLQQ 345
EE++ +A Q + L+ E ++L+Q
Sbjct: 450 RDEESVRIA-QTRLLEEEEEKLKQ 472
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 42.7 bits (99), Expect = 5e-04
Identities = 46/187 (24%), Positives = 79/187 (42%), Gaps = 15/187 (8%)
Query: 157 LLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216
+LRL Q + + +R L A+EE AR RL L + S + + E
Sbjct: 633 ILRLHQQ-KEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAE 691
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276
EA Q+LRE+ + + + LEQK +Q+K + E E+ ++ L+
Sbjct: 692 QEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQL 751
Query: 277 LEALQEERN----TAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQ 332
E L+ ER T E++ +A + + A+ V+ +L++ I A Q
Sbjct: 752 REQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVV----------SSLQKKIQEAQQ 801
Query: 333 NQELQAE 339
+E Q +
Sbjct: 802 KEEAQLQ 808
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 42.7 bits (99), Expect = 5e-04
Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 16/154 (10%)
Query: 208 SQLGRALRELEAQRQRLREQHQIWI-----REKLKHLEQKEEVADDQVKGLVAEEEAC-- 260
+ LGR E+E + R + ++ +L ++++ + +++ + A+ E
Sbjct: 1458 ANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKV 1517
Query: 261 ---EERQRWQQEQMVLRF---QLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISG 314
EERQR+Q+E+ L QLE Q E+ ++L+ QA++ Q + +
Sbjct: 1518 KVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQA 1577
Query: 315 DGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
GG + +E L Q ELQA+ Q +Q A+
Sbjct: 1578 QGG---ESQQEAQRLQAQLNELQAQLSQKEQAAE 1608
Score = 33.5 bits (75), Expect = 0.29
Identities = 34/144 (23%), Positives = 59/144 (40%), Gaps = 17/144 (11%)
Query: 208 SQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQ 267
SQ+ R + +L + L + +RE HL+Q ++ ++ EE + Q W
Sbjct: 307 SQMDRKINQLSEENGDLSFK----LREFASHLQQLQDALNE------LTEEHSKATQEWL 356
Query: 268 QEQMVLRFQLEA-------LQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLA 320
++Q L +L A L+E+ + L+ L + Q + GD L
Sbjct: 357 EKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLE 416
Query: 321 GTLEETINLATQNQELQAENQQLQ 344
+E LA N +LQA + L+
Sbjct: 417 TLKQEAATLAANNTQLQARVEMLE 440
Score = 32.0 bits (71), Expect = 0.84
Identities = 26/114 (22%), Positives = 59/114 (51%), Gaps = 2/114 (1%)
Query: 178 DAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLK 237
+A+E+ +A + + +L + + DS + + +A RE +++ E + +
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEA-RDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665
Query: 238 HLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDL 291
E + +VA+ +++ L +E++ E++R QE+ L+ QL+AL+E + L
Sbjct: 666 QHEAQAQVAELELQ-LRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSL 718
Score = 31.6 bits (70), Expect = 1.1
Identities = 36/156 (23%), Positives = 68/156 (43%), Gaps = 16/156 (10%)
Query: 205 SGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE------ 258
+GL Q + + AQ + +EQ +R +++ L + + Q+K + ++E
Sbjct: 522 AGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDH 581
Query: 259 ------ACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPI 312
A EER+ +E+ QLEAL++E+ + L + +A + V
Sbjct: 582 AQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQA 641
Query: 313 SGDGGLLAGTLEE---TINLATQNQ-ELQAENQQLQ 344
+ L+ +EE + A Q Q E QA+ +L+
Sbjct: 642 QREKAELSRKVEELQACVETARQEQHEAQAQVAELE 677
Score = 30.8 bits (68), Expect = 1.9
Identities = 43/169 (25%), Positives = 72/169 (42%), Gaps = 17/169 (10%)
Query: 181 EEARARRAGLRPLRLGLLEDTLTDS-GLSQLGRALRELEAQRQRLREQHQIWIREKLKHL 239
E+ +A + L+ + L E+ + L + R + EL+A+ + L EQH+ RE+ K L
Sbjct: 702 EQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK---RER-KEL 757
Query: 240 EQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHV 299
E++ KGL A + E Q E VLR +L ++TAE + L V
Sbjct: 758 EEERAGR----KGLEARLQQLGEAH--QAETEVLRRELAEAMAAQHTAESECEQL----V 807
Query: 300 QATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQGAD 348
+ A + +E L T +E + Q+LQ+ +
Sbjct: 808 KEVAAWRERYEDSQQEEAQYGAMFQE--QLMTLKEECEKARQELQEAKE 854
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/169 (26%), Positives = 72/169 (42%), Gaps = 33/169 (19%)
Query: 198 LEDTLTDSGLSQLGRALRELEAQRQRLRE--------QHQIWI------REKLKHLEQKE 243
L+ DSG+ + + +EL+ + +R R+ Q +IW +E + E +
Sbjct: 880 LQRNRPDSGVEEAWKIRKELDEETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLK 939
Query: 244 EVAD-------DQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYD 296
+V D Q++ +AEE+ + Q Q+E L+ QL AL++E Q+
Sbjct: 940 KVPDPVLEESFQQLQRTLAEEQ--HKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEV 997
Query: 297 LHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQLQQ 345
L ++ RAQ VL + EE L Q +AE LQQ
Sbjct: 998 LRIEPDRAQADEVLQLR----------EELEALRRQKGAREAEVLLLQQ 1036
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 4/137 (2%)
Query: 208 SQLGRALRELEAQRQRLREQHQ--IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR 265
++L R L ELE +RQ RE + ++++L LEQ+E A ++V ++ ++ +
Sbjct: 1397 TELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTH--TQKVVLQQDPQ 1454
Query: 266 WQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEE 325
+E +LR QLE Q R E +L L +A+ + +S + G E+
Sbjct: 1455 QAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKGDTEQ 1514
Query: 326 TINLATQNQELQAENQQ 342
I + E ++ +++
Sbjct: 1515 EIQRLKSSLEEESRSKR 1531
Score = 31.2 bits (69), Expect = 1.4
Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 37/139 (26%)
Query: 157 LLRLDP-QGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLE--------------DT 201
+LR++P + + +V Q+R L EA R+ G R + LL+ +
Sbjct: 997 VLRIEPDRAQADEVLQLREEL-----EALRRQKGAREAEVLLLQQRVAALAEEKSRAQEK 1051
Query: 202 LTDSGLSQLGRALRELEAQRQRLREQHQ-------------IWIREKLKHLEQKEEVADD 248
+T+ + +L +LEA+ Q+L+E HQ ++++KLK LE++ +A+
Sbjct: 1052 VTEKEVVKLQND-PQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEG 1110
Query: 249 QV---KGLVAEEEACEERQ 264
++ + L E++A ER+
Sbjct: 1111 KITVKEVLKVEKDAATERE 1129
Score = 29.6 bits (65), Expect = 4.2
Identities = 35/142 (24%), Positives = 64/142 (45%), Gaps = 23/142 (16%)
Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227
+VK + +W + + + +R L + D + + QL R L E + + Q L+E+
Sbjct: 912 EVKSTQEEIW-TLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQLLQEE 970
Query: 228 HQIWIREKLKHLEQK------------------EEVADDQVKGLVAEEEACEERQRWQQE 269
+ ++ +L+ LEQ+ + D+V L E EA RQ+ +E
Sbjct: 971 LEA-LQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALR-RQKGARE 1028
Query: 270 QMVLRFQ--LEALQEERNTAEQ 289
VL Q + AL EE++ A++
Sbjct: 1029 AEVLLLQQRVAALAEEKSRAQE 1050
Score = 28.5 bits (62), Expect = 9.3
Identities = 29/120 (24%), Positives = 57/120 (47%), Gaps = 18/120 (15%)
Query: 180 VEEARARRAGLRPLR--LGLLEDTLTDSGLSQLGR-----ALRELEAQRQRLREQHQIW- 231
+E+ RA G ++ L + +D T+ +S L R A + +QR++ +IW
Sbjct: 1101 LEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160
Query: 232 ---------IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQM-VLRFQLEALQ 281
++EK++ + + + A+ +V L E E + R +EQ+ + +LEAL+
Sbjct: 1161 LEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALR 1220
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/140 (20%), Positives = 69/140 (49%), Gaps = 8/140 (5%)
Query: 214 LRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQ--- 270
L E + Q + ++ +++K +H E+K +V D+Q+K +A++E E + +E+
Sbjct: 696 LEEKHREAQVSAQHLEVHLKQKEQHYEEKIKVLDNQIKKDLADKETLENMMQRHEEEAHE 755
Query: 271 --MVLRFQ---LEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEE 325
+L Q + A+ + + EQ + L + + A + + +++ ++
Sbjct: 756 KGKILSEQKAMINAMDSKIRSLEQRIVELSEANKLAANSSLFTQRNMKAQEEMISELRQQ 815
Query: 326 TINLATQNQELQAENQQLQQ 345
L TQ +L+A+N++L++
Sbjct: 816 KFYLETQAGKLEAQNRKLEE 835
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/137 (24%), Positives = 67/137 (48%), Gaps = 10/137 (7%)
Query: 215 RELEAQRQRLREQHQIW---IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ--- 268
+EL+ + Q + +Q Q+ ++E+ + +Q+E++ Q + E++ +++++ QQ
Sbjct: 144 QELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQ----EQQVLQQQEQLQQQVQ 199
Query: 269 EQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETIN 328
EQ +L+ Q E LQ+++ +Q+ Q + Q L + G L L +
Sbjct: 200 EQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQ 259
Query: 329 LATQNQELQAENQQLQQ 345
Q Q L+ + QLQQ
Sbjct: 260 AQLQQQLLEQQQAQLQQ 276
Score = 35.0 bits (79), Expect = 0.100
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 160 LDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRAL-RELE 218
L Q ++Q +Q++P + EE L P+ LG ++ L Q + L R+ E
Sbjct: 295 LQQQQEQLQQQQLQPPPLEPEEEEEVELE-LMPVDLG------SEQELEQQRQELERQQE 347
Query: 219 AQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLE 278
+RQ+ + Q Q+ ++E+L+ LEQ+ E Q++ + E QQ+++ L +L
Sbjct: 348 LERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL--ELT 405
Query: 279 ALQEE 283
+Q E
Sbjct: 406 PVQPE 410
Score = 34.7 bits (78), Expect = 0.13
Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 5/135 (3%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVA----DDQVKGLVAEEEACEERQRWQQEQ 270
++ + Q Q+++EQ ++ +++ +Q +E +Q++ V E++ +++Q Q+Q
Sbjct: 155 QQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ 214
Query: 271 MVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLA 330
+L+ Q + Q++ ++ L L + + Q L + L L E
Sbjct: 215 QLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL-LQQQQAQLQQQLLEQQQAQ 273
Query: 331 TQNQELQAENQQLQQ 345
Q Q L + +QLQQ
Sbjct: 274 LQQQLLLQQQEQLQQ 288
Score = 30.8 bits (68), Expect = 1.9
Identities = 41/191 (21%), Positives = 82/191 (42%), Gaps = 35/191 (18%)
Query: 163 QGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQ 222
Q + QV Q + L V+E + L ++ L L Q L++ + Q+Q
Sbjct: 181 QAQEQQVLQQQEQLQQQVQEQQL---------LQQQQEQLQQQQLLQQQEQLQQQQFQQQ 231
Query: 223 R--LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEAL 280
+ L++Q Q+ + ++ L+Q+ L+ +++A ++Q +Q+Q L+ QL L
Sbjct: 232 QEQLQQQQQLLLLQQQGQLQQQ----------LLQQQQAQLQQQLLEQQQAQLQQQL-LL 280
Query: 281 QEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLAT------QNQ 334
Q++ +Q L + + Q P+ + EE + L Q
Sbjct: 281 QQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEE-------EEEVELELMPVDLGSEQ 333
Query: 335 ELQAENQQLQQ 345
EL+ + Q+L++
Sbjct: 334 ELEQQRQELER 344
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/89 (28%), Positives = 53/89 (59%), Gaps = 4/89 (4%)
Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
++ Q++++REQ + IW +E+ K EQ+E + + + K EE+ CE+ ++ Q+++ +R
Sbjct: 579 KIREQKEKIREQEEKIWEQEE-KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
Query: 275 FQLEAL--QEERNTAEQDLAALYDLHVQA 301
Q E + QE R +++ + H++A
Sbjct: 638 RQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 38.5 bits (88), Expect = 0.009
Identities = 17/77 (22%), Positives = 48/77 (62%), Gaps = 1/77 (1%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++REQ + IRE+ + + ++EE+ +Q + + +EE +E+++ ++++ +R Q E
Sbjct: 521 QEEKIREQEEK-IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEK 579
Query: 280 LQEERNTAEQDLAALYD 296
++E++ + +++
Sbjct: 580 IREQKEKIREQEEKIWE 596
Score = 37.4 bits (85), Expect = 0.020
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 6/81 (7%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQK----EEVADDQVKGLVAEEEACEERQR--WQQE 269
E+ Q +++REQ +IW +++ H ++K EE Q + + +EE E++ W+QE
Sbjct: 463 EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
Query: 270 QMVLRFQLEALQEERNTAEQD 290
+ + + + ++E EQ+
Sbjct: 523 EKIREQEEKIREQEEKIREQE 543
Score = 36.6 bits (83), Expect = 0.034
Identities = 19/83 (22%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
++ R ++ Q + +++ ++W +E+ H +Q+E++ + + K EE+ E+ ++ ++
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEKVWRQEEKMH-DQEEKIREQEEKMWRQEEKIREQEEKIRE 534
Query: 269 EQMVLRFQLEALQE-ERNTAEQD 290
++ +R Q E +QE E EQ+
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQE 557
Score = 36.2 bits (82), Expect = 0.045
Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 6/78 (7%)
Query: 212 RALRELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQR 265
R ++ Q +++REQ + +W IRE+ + + ++EE +Q + + +EE E++
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
Query: 266 WQQEQMVLRFQLEALQEE 283
QEQ +R Q E ++E+
Sbjct: 559 KMQEQEKMRRQEEKIREQ 576
Score = 35.4 bits (80), Expect = 0.076
Identities = 21/87 (24%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVL 273
++ Q +++REQ + IRE+ + + ++EE +Q + + +EE +E++ W+QE+ +
Sbjct: 565 KMRRQEEKIREQEE-KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMC 623
Query: 274 RFQLEALQEERNTAEQDLAALYDLHVQ 300
Q E +QE+ + +++ V+
Sbjct: 624 E-QEEKMQEQEEKMRRQEEKMWEQEVR 649
Score = 33.9 bits (76), Expect = 0.22
Identities = 30/131 (22%), Positives = 67/131 (51%), Gaps = 12/131 (9%)
Query: 168 QVKQVRPTLWDAVEEARARRAGL--RPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLR 225
++++ +W+ E+ R + + + ++ LE+ + + + R L E +++++R
Sbjct: 336 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK--EEKIRELEEKMHEQEKIR 393
Query: 226 EQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACE-ERQRWQQEQMVLRFQLEA 279
EQ + IRE+ K EQ+ ++ + K EE+ E E++ W+QE+ + + E
Sbjct: 394 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI--HEQEK 451
Query: 280 LQEERNTAEQD 290
++EE EQ+
Sbjct: 452 IREEEKRQEQE 462
Score = 33.1 bits (74), Expect = 0.38
Identities = 22/113 (19%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIR----EKLKHLEQKEEVADDQVKG 252
LL + LG+ L+ + A+ Q E++++W R ++ K Q+E++ + + K
Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQ 305
EE+ E+ ++ ++++ +R Q E + E+ + +++ + R +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369
Score = 32.7 bits (73), Expect = 0.49
Identities = 20/81 (24%), Positives = 45/81 (55%), Gaps = 4/81 (4%)
Query: 208 SQLGRALRELEAQRQRLREQHQ-IWIREKLKHLEQK---EEVADDQVKGLVAEEEACEER 263
+++ R ++ Q +++REQ + +W +E+ H ++K EE +Q + EE+ E+
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 264 QRWQQEQMVLRFQLEALQEER 284
+ W+Q++ + + QEE+
Sbjct: 476 EIWRQKEKMHEQEKIRKQEEK 496
Score = 31.2 bits (69), Expect = 1.4
Identities = 27/131 (20%), Positives = 60/131 (45%), Gaps = 7/131 (5%)
Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLR 225
++Q + LW+ + + + + + ++ E+ + + ++ ++ Q +++R
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-EKIREQEEKIREQEEKMR 338
Query: 226 EQHQI-WIRE-KLKHLEQ----KEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q ++ W +E K++ E+ KEE + + +EE E + EQ +R Q E
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK 398
Query: 280 LQEERNTAEQD 290
QEE EQ+
Sbjct: 399 RQEEEKIREQE 409
Score = 30.0 bits (66), Expect = 3.2
Identities = 20/87 (22%), Positives = 45/87 (51%), Gaps = 14/87 (16%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVK------------GLVAEEEACEER 263
++ Q +R ++ ++W R++ K EQ+E++ + + K + EE+ E+
Sbjct: 404 KIREQEKRQEQEAKMW-RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290
+ W+QE+ + R Q E +++ EQ+
Sbjct: 463 EMWRQEEKI-REQEEIWRQKEKMHEQE 488
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 3/121 (2%)
Query: 173 RPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWI 232
R T+ EE R L E+ L +L R +E E Q+QRLR + Q+
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
Query: 233 REKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ---EQMVLRFQLEALQEERNTAEQ 289
+++ + EQ+EE + Q + EE ++ +R Q+ EQ + R Q E +E++ EQ
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 290 D 290
+
Sbjct: 369 E 369
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/150 (26%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 147 LLEGNNYSGLLLRLDPQGRRMQVKQV--RPTLWDAVEEARARRAGLRPLRLGLLED---- 200
L EG S RL+ + R+ + +++ + W EE RA L+ + E+
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 201 -TLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA 259
L L +L R RE E Q+QR Q +++ E+ K ++E V + + L EEE
Sbjct: 208 EQLRRRELLELRRKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL-QEEEP 265
Query: 260 CEERQRWQQEQMVLRFQLEALQEERNTAEQ 289
+R+ ++E+ + + + + L+ ER EQ
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQ 295
Score = 38.5 bits (88), Expect = 0.009
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 5/86 (5%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
Q R RE E + Q L E+ Q+ RE+ + L+++E+ + + ++E+ +++ RWQ
Sbjct: 819 QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQL 878
Query: 269 EQMVLR-----FQLEALQEERNTAEQ 289
E+ R + ALQE+ +Q
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQ 904
Score = 34.3 bits (77), Expect = 0.17
Identities = 38/143 (26%), Positives = 68/143 (47%), Gaps = 23/143 (16%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
L+L+ + RR Q ++ L EE R +R L+ + L Q R+ ++L
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQR----------LKRQEEEERLQQRLRSEQQL 538
Query: 218 EAQRQRLREQHQIWIREKLKHLEQ-------KEEVADDQVKGLVAEEEACEERQRWQQ-- 268
+++ REQ + RE+ K LEQ K E + + + L EEE ++R + +Q
Sbjct: 539 RREQEERREQ--LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 269 --EQMVLRFQLEALQEERNTAEQ 289
EQ + R ++E L++E ++
Sbjct: 597 RLEQRLKREEVERLEQEERREQR 619
Score = 33.1 bits (74), Expect = 0.38
Identities = 33/131 (25%), Positives = 60/131 (45%), Gaps = 11/131 (8%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
R+L A+ ++ REQ + E+ + ++ + +++ + EEE + R+R QQ Q
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ-FLEEEEQLQRRERAQQLQEE-E 853
Query: 275 FQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQNQ 334
L+ QE R + EQ + ++ R + H L L+E L + Q
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL-------YAKPALQE--QLRKEQQ 904
Query: 335 ELQAENQQLQQ 345
LQ E ++LQ+
Sbjct: 905 LLQEEEEELQR 915
Score = 32.7 bits (73), Expect = 0.49
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 12/131 (9%)
Query: 158 LRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALREL 217
LR + Q RR Q ++ R L EE R + R RL ++ D L RE
Sbjct: 532 LRSEQQLRREQEER-REQLLKREEEKRLEQER-REQRLKREQEERRDQLLK------REE 583
Query: 218 EAQRQRLREQHQIWIREKLKHLE----QKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273
E ++QRL+ + + + ++LK E ++EE + ++K EEE ++ + ++++
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 274 RFQLEALQEER 284
+ QL Q+ER
Sbjct: 644 QQQLRREQQER 654
Score = 32.0 bits (71), Expect = 0.84
Identities = 22/85 (25%), Positives = 40/85 (47%), Gaps = 7/85 (8%)
Query: 212 RALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC-------EERQ 264
R RE + R + R+ W E+L+ EQ++ + ++ + AEE+ EE++
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Query: 265 RWQQEQMVLRFQLEALQEERNTAEQ 289
WQ+E+ R + E E + Q
Sbjct: 1864 LWQEEEQKRRQERERKLREEHIRRQ 1888
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275
+LE Q QRLR++ R + + Q++ ++Q E++ +ER+R +E+ + R
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Query: 276 QLEALQEERNTAE 288
Q E Q R E
Sbjct: 1889 QKEE-QRHRQVGE 1900
Score = 30.8 bits (68), Expect = 1.9
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 15/110 (13%)
Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLE 240
EE RAR G + LL+D + + R+LE + + R Q K E
Sbjct: 97 EEKRARCDG----KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ---------KRQE 143
Query: 241 QKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290
Q+ E+A+ + + ++E E+R R ++++ + R + E + E AE++
Sbjct: 144 QERELAEGEEQS--EKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEE 191
Score = 30.8 bits (68), Expect = 1.9
Identities = 17/75 (22%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
R+ + +R + E+ + W++ + + +++E + Q++ +EE E+R + Q+E+ L+
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR--EQEERREQRLKRQEEEERLQ 529
Query: 275 FQLEALQEERNTAEQ 289
+L + Q+ R E+
Sbjct: 530 QRLRSEQQLRREQEE 544
Score = 30.4 bits (67), Expect = 2.5
Identities = 24/77 (31%), Positives = 39/77 (50%), Gaps = 9/77 (11%)
Query: 216 ELEAQRQRL-REQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
E E + QRL REQ + R+ LK E+ E ++ K + ++ E R+RW L+
Sbjct: 439 EQERREQRLKREQEER--RDWLKREEETERHEQERRKQQLKRDQEEERRERW------LK 490
Query: 275 FQLEALQEERNTAEQDL 291
+ E +E++ EQ L
Sbjct: 491 LEEEERREQQERREQQL 507
Score = 30.4 bits (67), Expect = 2.5
Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 8/90 (8%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVAD-DQVKGLVAEEEACEERQRW- 266
Q G+ R+ + +++R RE W E+ H +Q+EE D AEE++ RQR
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 267 ------QQEQMVLRFQLEALQEERNTAEQD 290
+Q + LR + +E+R E++
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEE 815
Score = 30.4 bits (67), Expect = 2.5
Identities = 19/82 (23%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 218 EAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQ----RWQQEQMVL 273
+ + Q LRE+ + R++L+ ++EE + + L+ EE RQ ++++E+ +
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 274 RFQLEALQEERNTAEQDLAALY 295
+ + + L+EE+ Q+ Y
Sbjct: 1178 QEEEQLLREEQEKRRQERERQY 1199
Score = 29.6 bits (65), Expect = 4.2
Identities = 23/72 (31%), Positives = 41/72 (56%), Gaps = 8/72 (11%)
Query: 214 LRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQMV 272
LRE +R+R + Q K K L+QKEE Q+ G E+ +ER+ ++++E+ +
Sbjct: 944 LREEREKRRRQERERQY---RKDKKLQQKEE----QLLGEEPEKRRRQEREKKYREEEEL 996
Query: 273 LRFQLEALQEER 284
+ + + L+EER
Sbjct: 997 QQEEEQLLREER 1008
Score = 29.3 bits (64), Expect = 5.5
Identities = 26/125 (20%), Positives = 59/125 (47%), Gaps = 5/125 (4%)
Query: 165 RRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRL 224
RR + K+++ + + R R L+ GL ED Q + + +R
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
Query: 225 REQHQIWIREKL-KHLEQKEEVADDQVKGLVAEEEACEERQ----RWQQEQMVLRFQLEA 279
R +H ++ + L + L +++++ ++ + L EE RQ ++++E+ + + + +
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
Query: 280 LQEER 284
L+EER
Sbjct: 944 LREER 948
Score = 29.3 bits (64), Expect = 5.5
Identities = 31/130 (23%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 161 DPQGRRMQVKQVRPTLWD-AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA 219
+ Q RR +Q R W +EE R RR + L E + L Q E
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ--------EE 909
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
+ + RE+ + R++ + ++EE + + L+ EE E+R+R ++E+ + +
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER--EKRRRQERERQYRKDKKLQ 967
Query: 280 LQEERNTAEQ 289
+EE+ E+
Sbjct: 968 QKEEQLLGEE 977
Score = 28.9 bits (63), Expect = 7.1
Identities = 22/86 (25%), Positives = 46/86 (53%), Gaps = 8/86 (9%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKE--------EVADDQVKGLVAEEEAC 260
QL ++ + E ++Q+LR + Q ++LK E++E E +++ + +AEEE
Sbjct: 632 QLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Query: 261 EERQRWQQEQMVLRFQLEALQEERNT 286
+ R+R + ++QLE+ + R +
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQS 717
Score = 28.9 bits (63), Expect = 7.1
Identities = 38/160 (23%), Positives = 60/160 (37%), Gaps = 17/160 (10%)
Query: 197 LLEDTLTDSGLSQLGRALRELEA----QRQRLREQHQIWIREKLKHLEQKEEVADDQVKG 252
LL + L + R RE E + Q L E+ + R++L+ +KEE + +
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQ 1092
Query: 253 LVAEE----------EACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQAT 302
L+ EE C E + QQE+ L L +E+R E + + VQ
Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQL---LREEREKRRRQELERQYREEEEVQQE 1149
Query: 303 RAQTHHVLPISGDGGLLAGTLEETINLATQNQELQAENQQ 342
Q P L E L + ++L E Q+
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189
Score = 28.5 bits (62), Expect = 9.3
Identities = 36/143 (25%), Positives = 64/143 (44%), Gaps = 16/143 (11%)
Query: 159 RLDPQGRRMQVKQVRPTLWDAV--EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216
RL+ + R ++K+ + D + E R+ L+ + LE L + +L +
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERL----EQ 612
Query: 217 LEAQRQRL-REQHQIWIREKLKHLEQKEEVADDQVKG---------LVAEEEACEERQRW 266
E + QRL RE+ + R++L E++EE Q++ L EEE QR
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 267 QQEQMVLRFQLEALQEERNTAEQ 289
++E R + E +EE+ A +
Sbjct: 673 KREHEEERREQELAEEEQEQARE 695
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 40.8 bits (94), Expect = 0.002
Identities = 44/183 (24%), Positives = 82/183 (44%), Gaps = 12/183 (6%)
Query: 169 VKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSG-LSQLGRALRELEAQRQRLREQ 227
VK+ L +EA R GL+ G E G ++ L R ++ +E + R +E+
Sbjct: 10 VKRKIQALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQER 69
Query: 228 HQIWIREKLKHLEQKEEVADDQVKGL-VAEEEACEERQRWQQEQMVLRFQLEALQEERNT 286
+ L+ LE+ E+ AD+ +G+ V E A ++ ++ + ++M L+ +E
Sbjct: 70 ----LATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRK 125
Query: 287 AEQDLAALYDLHVQATRAQTHHVLPISGDGGLLAGTLEETINLATQN-QELQAENQQLQQ 345
E+ L L + RA+ + L G LEE + T N + L+A +++ +
Sbjct: 126 YEEVARKLVILEGELERAEERAEV-----SELKCGDLEEELKNVTNNLKSLEAASEKYSE 180
Query: 346 GAD 348
D
Sbjct: 181 KED 183
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 40.4 bits (93), Expect = 0.002
Identities = 31/138 (22%), Positives = 66/138 (47%), Gaps = 8/138 (5%)
Query: 159 RLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELE 218
RL Q +M+ ++ + +W + R + LR L E Q+ ++
Sbjct: 301 RLREQEGKMREQEEK--MWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMW 358
Query: 219 AQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMV 272
Q +++REQ + +W + E+ K + ++E+ DQ + + ++E E++ +EQ
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 273 LRFQLEALQEERNTAEQD 290
+ Q+E ++EE+ EQ+
Sbjct: 419 MWEQVEKMREEKKMQEQE 436
Score = 38.5 bits (88), Expect = 0.009
Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 6/93 (6%)
Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQV 250
LL T++ ++ R EL Q +++R+Q + +W +RE+ + ++EE Q
Sbjct: 261 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE 320
Query: 251 KGLVAEEEACEERQRWQQEQMVLRFQLEALQEE 283
K L +E+ E+++ +EQ LR Q E +QE+
Sbjct: 321 KRLREQEKELREQEKELREQKELREQEEQMQEQ 353
Score = 37.7 bits (86), Expect = 0.015
Identities = 21/83 (25%), Positives = 50/83 (60%), Gaps = 4/83 (4%)
Query: 216 ELEAQRQRLREQHQIWIREKL-KHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQMVL 273
+++ Q + ++ +IW +EK+ K +++E+ DQ K + EEE+ ER+ + ++E+ ++
Sbjct: 672 KMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK--MREEESMREREKKMREEEEMM 729
Query: 274 RFQLEALQEERNTAEQDLAALYD 296
R Q E +QE+ ++ +++
Sbjct: 730 REQEEKMQEQEEKMQEQEEEMWE 752
Score = 36.6 bits (83), Expect = 0.034
Identities = 30/130 (23%), Positives = 64/130 (49%), Gaps = 9/130 (6%)
Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA----QR 221
++Q ++ +W EE R + +R + + L + +RE E Q
Sbjct: 264 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQ---EERLREQEGKMREQEEKMWRQE 320
Query: 222 QRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRW-QQEQMVLRFQLEAL 280
+RLREQ + +RE+ K L +++E+ + + + EE+ E+ ++ +QE+ + R +
Sbjct: 321 KRLREQEKE-LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 281 QEERNTAEQD 290
++E+ EQ+
Sbjct: 380 EQEKQMREQE 389
Score = 36.6 bits (83), Expect = 0.034
Identities = 24/80 (30%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 214 LRELEAQRQR---LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQ 270
+RE E+ R+R +RE+ ++ +RE+ + ++++EE +Q + + +EE E++ EQ
Sbjct: 709 MREEESMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767
Query: 271 MVLRFQLEALQEERNTAEQD 290
L Q E L E EQ+
Sbjct: 768 QRLPEQKEKLWEHEKMQEQE 787
Score = 35.8 bits (81), Expect = 0.058
Identities = 23/81 (28%), Positives = 49/81 (60%), Gaps = 7/81 (8%)
Query: 214 LRELEAQRQR---LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQ 268
+RE E R+R +RE+ ++ +RE+ + ++++EE +Q + + +EE +E++ W+Q
Sbjct: 585 MREEERMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 269 EQMVLRFQLEALQEERNTAEQ 289
E+ + Q E + E++ EQ
Sbjct: 644 EEKMWE-QEEKMWEQQRLPEQ 663
Score = 35.4 bits (80), Expect = 0.076
Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 5/84 (5%)
Query: 212 RALRELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRW 266
R ++++ Q ++ R+Q + IRE+ K + ++EE +Q + + +EE E++
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 267 QQEQMVLRFQLEALQEERNTAEQD 290
+ +Q L Q E L E+ EQ+
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQE 510
Score = 34.7 bits (78), Expect = 0.13
Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 17/90 (18%)
Query: 217 LEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQ------- 264
L + +R+REQ ++W +RE+ K EQ+++ D + K + EEE ER+
Sbjct: 406 LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK--MQEEERIREREKKMREEE 463
Query: 265 ---RWQQEQMVLRFQLEALQEERNTAEQDL 291
R Q+E+M + + QEE+ +Q L
Sbjct: 464 ETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Score = 33.9 bits (76), Expect = 0.22
Identities = 19/71 (26%), Positives = 43/71 (60%), Gaps = 5/71 (7%)
Query: 221 RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVLRFQLE 278
++++RE+ + RE+ K + ++EE+ +Q + + +EE +E++ W+QE+ + Q E
Sbjct: 706 QEKMREEESM--REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWE-QEE 762
Query: 279 ALQEERNTAEQ 289
+ E++ EQ
Sbjct: 763 KMWEQQRLPEQ 773
Score = 33.5 bits (75), Expect = 0.29
Identities = 22/82 (26%), Positives = 48/82 (58%), Gaps = 7/82 (8%)
Query: 220 QRQRLREQHQ-IWIREKL---KHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQMVLR 274
Q +++R+Q Q +W +E+ K EQ+++ D + K + EEE ER+ + ++E+ ++R
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEK--MREEERMREREKKMREEEEMMR 606
Query: 275 FQLEALQEERNTAEQDLAALYD 296
Q E +QE+ ++ +++
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWE 628
Score = 33.1 bits (74), Expect = 0.38
Identities = 22/76 (28%), Positives = 44/76 (57%), Gaps = 10/76 (13%)
Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
E E Q+QRL EQ + +W +EK++ EQ+E++ + EE+ ++ + W QE+ + R
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQ--EQEEKIWEQ-------EEKIRDQEEMWGQEKKMWR 535
Query: 275 FQLEALQEERNTAEQD 290
+ QE++ +++
Sbjct: 536 QEKMREQEDQMWEQEE 551
Score = 32.7 bits (73), Expect = 0.49
Identities = 20/75 (26%), Positives = 41/75 (54%), Gaps = 3/75 (4%)
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQEQMVLRF 275
+ Q ++++EQ + ++ K EQ+E++ + + K EE+ E+ ++ W+Q++ L
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR--LPE 662
Query: 276 QLEALQEERNTAEQD 290
Q E L E EQ+
Sbjct: 663 QKEKLWEHEKMQEQE 677
Score = 32.3 bits (72), Expect = 0.65
Identities = 17/75 (22%), Positives = 45/75 (60%), Gaps = 2/75 (2%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275
+++ Q ++++EQ + ++ K EQ+E++ + + K EE+ E+++ +Q++ + +
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL--W 668
Query: 276 QLEALQEERNTAEQD 290
+ E +QE+ EQ+
Sbjct: 669 EHEKMQEQEKMQEQE 683
Score = 32.3 bits (72), Expect = 0.65
Identities = 18/76 (23%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
+++ + + +REQ + ++ K EQ+EE+ + + K EE+ E+++ +Q++ +
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL-- 777
Query: 275 FQLEALQEERNTAEQD 290
++ E +QE+ EQ+
Sbjct: 778 WEHEKMQEQEKIWEQE 793
Score = 32.0 bits (71), Expect = 0.84
Identities = 24/78 (30%), Positives = 44/78 (56%), Gaps = 7/78 (8%)
Query: 220 QRQRLREQHQ-IWIREKLKHLE---QKEEVADDQVKGLVAEEEAC---EERQRWQQEQMV 272
++QRL EQ + +W EK++ E ++EE DQ + + +EE EE+ R Q+E+M
Sbjct: 766 EQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMW 825
Query: 273 LRFQLEALQEERNTAEQD 290
+ + QEE+ +++
Sbjct: 826 GQEEKMWGQEEKMWGQEE 843
Score = 30.8 bits (68), Expect = 1.9
Identities = 19/89 (21%), Positives = 44/89 (49%), Gaps = 17/89 (19%)
Query: 220 QRQRLREQHQIW-----------IREKLKHLEQKEEVADDQVKGLVAEEEACE------E 262
Q +++R+Q ++W +RE+ + ++EE DQ + + +EE E E
Sbjct: 516 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQE 575
Query: 263 RQRWQQEQMVLRFQLEALQEERNTAEQDL 291
++ W QE+ + + +E++ E+++
Sbjct: 576 KKTWDQEEKMREEERMREREKKMREEEEM 604
Score = 29.6 bits (65), Expect = 4.2
Identities = 18/71 (25%), Positives = 42/71 (59%), Gaps = 6/71 (8%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++RE+ ++ RE+ K + ++EE+ +Q + + +EE +E Q+E+M + +
Sbjct: 581 QEEKMREEERM--REREKKMREEEEMMREQEEKMQEQEEKMQE----QEEKMWEQEEKMQ 634
Query: 280 LQEERNTAEQD 290
QEE+ +++
Sbjct: 635 EQEEKMWEQEE 645
Score = 29.3 bits (64), Expect = 5.5
Identities = 20/98 (20%), Positives = 47/98 (47%)
Query: 193 LRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKG 252
L L L +T+T+ L + L+E + + + Q+ ++E + LE+ + +
Sbjct: 209 LSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTN 268
Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290
+ EE +E + +QE+ + + + + ++E EQ+
Sbjct: 269 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE 306
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 10/83 (12%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--------WQ 267
E+ Q +++ EQ +IW R+K K EQ+E++ + K EE+ E+ ++ W+
Sbjct: 477 EMWRQEEKIHEQEEIW-RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535
Query: 268 QEQMVLRFQLEALQEERNTAEQD 290
QE+ + R Q E +EE EQ+
Sbjct: 536 QEEKI-REQEEMWREEEKMHEQE 557
Score = 38.9 bits (89), Expect = 0.007
Identities = 20/82 (24%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
++ R ++ Q +++R+Q + R++ K EQ+E++ + + K EE+ E+ + W++
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Query: 269 EQMVLRFQLEALQEERNTAEQD 290
E+ + + E + EE EQ+
Sbjct: 550 EEKM--HEQEKIWEEEKRQEQE 569
Score = 38.1 bits (87), Expect = 0.012
Identities = 19/77 (24%), Positives = 46/77 (59%), Gaps = 3/77 (3%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVL 273
+++ Q +++REQ + IRE+ + +++EE +Q + + +EE +E++ W+QE+ +
Sbjct: 620 KIQEQEEKIREQEEK-IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 274 RFQLEALQEERNTAEQD 290
+ + ++E EQ+
Sbjct: 679 EQEKKIREQEEKIREQE 695
Score = 37.4 bits (85), Expect = 0.020
Identities = 17/68 (25%), Positives = 41/68 (60%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
+++ Q +++REQ ++ ++ K EQ+E++ + + K EE+ + ++ ++++ LR
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
Query: 275 FQLEALQE 282
Q E +QE
Sbjct: 742 QQEEKMQE 749
Score = 37.0 bits (84), Expect = 0.026
Identities = 18/64 (28%), Positives = 38/64 (59%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++REQ + ++ K EQ+E + + + K EE+ CE+ ++ Q+++ +R Q E
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 732
Query: 280 LQEE 283
+ E+
Sbjct: 733 MWEQ 736
Score = 36.6 bits (83), Expect = 0.034
Identities = 22/72 (30%), Positives = 43/72 (59%), Gaps = 1/72 (1%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++REQ + R++ K EQ+E+ + + K EE+ E+ ++ Q+++ +R Q E
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 280 LQE-ERNTAEQD 290
++E E T EQ+
Sbjct: 635 IREQEEMTQEQE 646
Score = 36.6 bits (83), Expect = 0.034
Identities = 20/77 (25%), Positives = 48/77 (62%), Gaps = 3/77 (3%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA-CEERQRWQQEQMVLR 274
++ Q ++++EQ + IRE+ + + ++EE+ +Q + + +EE CE+ ++ Q+++ +
Sbjct: 613 KIREQEEKIQEQEEK-IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMW 671
Query: 275 FQLEALQE-ERNTAEQD 290
Q E ++E E+ EQ+
Sbjct: 672 RQEEKIREQEKKIREQE 688
Score = 36.6 bits (83), Expect = 0.034
Identities = 21/103 (20%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Query: 199 EDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEE 258
++ +T ++G ++ Q ++++EQ + R++ K EQ++++ + + K EE
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697
Query: 259 ACEERQR-WQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQ 300
E+ ++ W+QE+ + Q E +QE+ + +++ V+
Sbjct: 698 MQEQEEKMWEQEEKMCE-QEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 35.4 bits (80), Expect = 0.076
Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 15/93 (16%)
Query: 212 RALRELEAQRQRLREQHQIWIREKLKHLE-----QKEEVADDQVKGLVAEEEACEERQR- 265
R E+ + +++ EQ +IW EK + E Q+E++ + + K EE+ E+ ++
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 266 -------WQQEQMVLRFQLEALQE-ERNTAEQD 290
W+QE+ + R Q E +QE E EQ+
Sbjct: 601 QEQEEKMWKQEEKI-REQEEKIQEQEEKIREQE 632
Score = 34.7 bits (78), Expect = 0.13
Identities = 15/81 (18%), Positives = 45/81 (55%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275
++ Q +++REQ ++ ++ K EQ+E++ + + K EE + ++ ++++ +R
Sbjct: 627 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIRE 686
Query: 276 QLEALQEERNTAEQDLAALYD 296
Q E ++E+ ++ +++
Sbjct: 687 QEEKIREQEEMMQEQEEKMWE 707
Score = 33.5 bits (75), Expect = 0.29
Identities = 25/85 (29%), Positives = 46/85 (54%), Gaps = 8/85 (9%)
Query: 212 RALRELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACE-ERQR 265
R L E +++++REQ + IRE+ K EQ+ ++ + K EE+ E E++
Sbjct: 394 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM 453
Query: 266 WQQEQMVLRFQLEALQEERNTAEQD 290
W+QE+ + + E ++EE EQ+
Sbjct: 454 WRQEEKI--HEQEKIREEEKRQEQE 476
Score = 33.5 bits (75), Expect = 0.29
Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 3/71 (4%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++REQ + IRE+ K + ++EE +Q K + EE+ E+ + W+QE+ + Q E
Sbjct: 435 QEEKIREQEEK-IREQEKKMWRQEEKIHEQEK-IREEEKRQEQEEMWRQEEKI-HEQEEI 491
Query: 280 LQEERNTAEQD 290
+++ EQ+
Sbjct: 492 WRQKEKMHEQE 502
Score = 33.1 bits (74), Expect = 0.38
Identities = 22/113 (19%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIR----EKLKHLEQKEEVADDQVKG 252
LL + LG+ L+ + A+ Q E++++W R ++ K Q+E++ + + K
Sbjct: 257 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 316
Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQ 305
EE+ E+ ++ ++++ +R Q E + E+ + +++ + R +
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 369
Score = 32.7 bits (73), Expect = 0.49
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
Query: 218 EAQRQRLREQHQIWIRE-KLKHLEQ----KEEVADDQVKGLVAEEEACEERQRWQQEQMV 272
E + + R++ +W +E K++ E+ KEE Q + + +EE E + EQ
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 273 LRFQLEALQEERNTAEQD 290
+R Q E QEE EQ+
Sbjct: 406 IREQEEKRQEEEKIREQE 423
Score = 32.7 bits (73), Expect = 0.49
Identities = 16/71 (22%), Positives = 39/71 (54%), Gaps = 9/71 (12%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++REQ ++W E+ H ++E++ ++ E+ +E + W+QE+ + + +
Sbjct: 536 QEEKIREQEEMWREEEKMH--EQEKIWEE-------EKRQEQEDKMWRQEEKIREQEEKV 586
Query: 280 LQEERNTAEQD 290
++E EQ+
Sbjct: 587 WRQEEKIREQE 597
Score = 32.0 bits (71), Expect = 0.84
Identities = 19/87 (21%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 208 SQLGRALRELEAQRQRLREQHQ-IWIREKLKHLEQK---EEVADDQVKGLVAEEEACEER 263
+++ R ++ Q +++REQ + +W +E+ H ++K EE +Q + EE+ E+
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290
+ W+Q++ + + + ++E Q+
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/78 (26%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Query: 214 LRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273
+RE E +RQ ++ ++W +E+ K EQ+E++ + + K EE+ E+ + Q+++ +
Sbjct: 593 IREQEEKRQE--QEEKMWKQEE-KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 274 RFQLEAL-QEERNTAEQD 290
Q E + ++E EQ+
Sbjct: 650 GEQEEKMCEQEEKMQEQE 667
Score = 30.4 bits (67), Expect = 2.5
Identities = 20/71 (28%), Positives = 42/71 (59%), Gaps = 4/71 (5%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC---EERQRWQQEQMV 272
+++ Q +++REQ + IRE+ + + ++EE+ ++ + + +EE EE+ R Q+E M
Sbjct: 315 KIQEQEEKIREQEE-KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 373
Query: 273 LRFQLEALQEE 283
+ + QEE
Sbjct: 374 EKEEKMRRQEE 384
Score = 30.4 bits (67), Expect = 2.5
Identities = 16/72 (22%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +++REQ + ++ K +Q+E++ + + K EE+ E+ ++ ++++ + + Q E
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Query: 280 L-QEERNTAEQD 290
+ ++E EQ+
Sbjct: 649 MGEQEEKMCEQE 660
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 39.7 bits (91), Expect = 0.004
Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 11/85 (12%)
Query: 217 LEAQRQRLREQHQIW-----------IREKLKHLEQKEEVADDQVKGLVAEEEACEERQR 265
L + +R+REQ ++W IRE+ K + ++EE +Q + + +EE E++
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 427
Query: 266 WQQEQMVLRFQLEALQEERNTAEQD 290
+ +Q L Q E L E+ EQ+
Sbjct: 428 KEWQQQRLPEQKEKLWEQEKMQEQE 452
Score = 39.7 bits (91), Expect = 0.004
Identities = 27/81 (33%), Positives = 48/81 (59%), Gaps = 9/81 (11%)
Query: 217 LEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQ-RWQQEQ 270
L + +R+REQ ++W +RE+ K EQ+++ D + K + EEE ER+ + ++E+
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK--MREEERMREREKKMREEE 573
Query: 271 MVLRFQLEALQE-ERNTAEQD 290
++R Q E +QE E EQ+
Sbjct: 574 EMMREQEEKMQEQEEKMREQE 594
Score = 39.3 bits (90), Expect = 0.005
Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 6/93 (6%)
Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQV 250
LL T++ ++ R EL Q +++R+Q + +W +RE+ + ++EE Q
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282
Query: 251 KGLVAEEEACEERQRWQQEQMVLRFQLEALQEE 283
K L +E+ E+++ +EQ LR Q E +QE+
Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQ 315
Score = 39.3 bits (90), Expect = 0.005
Identities = 31/135 (22%), Positives = 66/135 (48%), Gaps = 12/135 (8%)
Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPL---------RLGLLEDTLTDSGLSQLGRALRE 216
++Q ++ +W EE R + +R RL E + + ++ R +
Sbjct: 226 QVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE-EKMRRQEKR 284
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQEQMVLRF 275
L Q + LREQ + +RE+ K EQ+E++ + + K EE+ E+ ++ W+QE+ +
Sbjct: 285 LREQEKELREQEKE-LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ 343
Query: 276 QLEALQEERNTAEQD 290
+ + ++E+ +Q+
Sbjct: 344 EKQMREQEQKMRDQE 358
Score = 37.4 bits (85), Expect = 0.020
Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 4/78 (5%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC--EERQRWQQEQMV 272
+EL Q + LREQ ++ RE+ + ++++EE +Q + + +EE +E + W+QE+ +
Sbjct: 290 KELREQEKELREQKKL--REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347
Query: 273 LRFQLEALQEERNTAEQD 290
+ + +E EQD
Sbjct: 348 REQEQKMRDQEERMWEQD 365
Score = 37.0 bits (84), Expect = 0.026
Identities = 38/173 (21%), Positives = 79/173 (45%), Gaps = 22/173 (12%)
Query: 135 EAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRP-L 193
E + +L + +W + + Y + L + + ++ R T+ + EE + + A L+ L
Sbjct: 142 ELQRALSAVSTWHKKADRY---IEELTKERDALSLELYRNTITN--EELKKKNAELQEKL 196
Query: 194 RLGLLEDTLTDSGLSQLGRALR----------------ELEAQRQRLREQHQIWIREKLK 237
RL E + + +L R L E+ Q + LREQ + +++ K
Sbjct: 197 RLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEK 256
Query: 238 HLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290
Q+E + + + K EE+ + +R ++++ LR Q + L+E++ EQ+
Sbjct: 257 MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309
Score = 36.6 bits (83), Expect = 0.034
Identities = 24/84 (28%), Positives = 51/84 (60%), Gaps = 10/84 (11%)
Query: 215 RELEAQRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQ-RWQ 267
+++ Q Q++R+Q + +W +REK + + ++E++ + + K + EEE ER+ + +
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK--MQEEERIREREKKMR 402
Query: 268 QEQMVLRFQLEALQ-EERNTAEQD 290
+E+ +R Q E +Q +E N EQ+
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQE 426
Score = 36.2 bits (82), Expect = 0.045
Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 18/89 (20%)
Query: 220 QRQRLREQHQIWIREKL------------KHLEQKEEVAD------DQVKGLVAEEEACE 261
Q +++R+Q ++W +EK + EQ+E++ D DQ + + ++E
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 262 ERQRWQQEQMVLRFQLEALQEERNTAEQD 290
E++ +EQ + Q E ++EE+ T EQ+
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQE 546
Score = 35.8 bits (81), Expect = 0.058
Identities = 29/124 (23%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 166 RMQVKQVRPT---LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQ-- 220
R Q K++R +W E R + +R + + L + + LRE E +
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQ---EKRLREQEKELREQEKELR 300
Query: 221 -RQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
+++LREQ + ++ K EQ+E++ + + K EE E+ ++ ++++ +R Q E
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 280 LQEE 283
+ E+
Sbjct: 361 MWEQ 364
Score = 35.8 bits (81), Expect = 0.058
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 12/87 (13%)
Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQK-----EEVADD-----QVKGLVAEEEACE-ER 263
E E Q+QRL EQ + +W +EK++ E+K E++ D Q K + +E+ E E
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290
Q W+QE+ + + + +E EQD
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQD 513
Score = 34.3 bits (77), Expect = 0.17
Identities = 20/77 (25%), Positives = 42/77 (54%), Gaps = 6/77 (7%)
Query: 220 QRQRLREQHQ-IW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273
Q +++REQ + +W + E+ K + ++E+ DQ + + ++E E++ +EQ +
Sbjct: 322 QEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 274 RFQLEALQEERNTAEQD 290
Q E +QEE E++
Sbjct: 382 WEQEEKMQEEERIRERE 398
Score = 34.3 bits (77), Expect = 0.17
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 8/110 (7%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEAC-EERQRWQQEQMV-- 272
+++ Q +++REQ + ++ K EQ+E++ + K EE+ +E + W QE+M
Sbjct: 668 KMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK 727
Query: 273 ---LRFQLEALQEERNTAEQDLA--ALYDLHVQATRAQTHHVLPISGDGG 317
+R Q E +QE E+ + L V + T V P G+ G
Sbjct: 728 EERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAG 777
Score = 33.5 bits (75), Expect = 0.29
Identities = 20/75 (26%), Positives = 43/75 (57%), Gaps = 4/75 (5%)
Query: 214 LRELEAQRQR---LREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQE 269
+RE E R+R +RE+ ++ ++ K EQ+E++ + + K EE+ E+ ++ W+QE
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 270 QMVLRFQLEALQEER 284
+ + + E +E+
Sbjct: 616 EKMWEQEEEDKMQEQ 630
Score = 33.1 bits (74), Expect = 0.38
Identities = 23/80 (28%), Positives = 48/80 (60%), Gaps = 7/80 (8%)
Query: 216 ELEAQRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEAC---EERQRWQQEQM 271
+++ Q +++ EQ + +W +E+ ++++EE+ +Q + + +EE EE+ R Q+E+M
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Query: 272 VLRFQLEALQ-EERNTAEQD 290
R Q E +Q +E EQ+
Sbjct: 663 --REQEEKMQGQEEKMREQE 680
Score = 33.1 bits (74), Expect = 0.38
Identities = 18/74 (24%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
Query: 218 EAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQL 277
+ + +++EQ ++ ++ K EQ+E++ + + K EE+ E+ ++ Q ++ +R Q
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQE 680
Query: 278 EALQ-EERNTAEQD 290
E +Q +E EQ+
Sbjct: 681 EKMQGQEEKMREQE 694
Score = 32.0 bits (71), Expect = 0.84
Identities = 18/73 (24%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q ++++EQ + ++ K EQ+E++ + + K EE+ E+ ++ Q ++ +R Q E
Sbjct: 637 QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEK 696
Query: 280 L--QEERNTAEQD 290
+ QEE+ +++
Sbjct: 697 MRGQEEKMWGQEE 709
Score = 31.6 bits (70), Expect = 1.1
Identities = 24/87 (27%), Positives = 50/87 (57%), Gaps = 9/87 (10%)
Query: 212 RALRELEAQRQRLREQHQ-IWIR-EKLKHLEQK----EEVADDQVKGLVAEEEAC--EER 263
R ++L Q ++++EQ + +W + EK++ E+K EE +Q K + +E+ +E
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290
+ W+Q++ LR + E ++E+ EQ+
Sbjct: 360 RMWEQDER-LREKEERMREQEKMWEQE 385
Score = 31.6 bits (70), Expect = 1.1
Identities = 23/77 (29%), Positives = 42/77 (54%), Gaps = 7/77 (9%)
Query: 220 QRQRLREQHQ-IWIREKL-----KHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVL 273
Q +++R+Q Q +W +E+ + L +KEE +Q K EE+ EE++ +QE+
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 274 RFQLEALQEERNTAEQD 290
Q E ++EE E++
Sbjct: 551 D-QEEKMREEERMRERE 566
Score = 31.2 bits (69), Expect = 1.4
Identities = 17/67 (25%), Positives = 42/67 (62%), Gaps = 4/67 (5%)
Query: 220 QRQRLREQHQ-IWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR--WQQEQMVLRFQ 276
Q ++++EQ + +W +E+ +++E+ +Q + + +EE +E++ W+QE+ +R Q
Sbjct: 600 QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK-MREQ 658
Query: 277 LEALQEE 283
E ++E+
Sbjct: 659 EEKMREQ 665
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/76 (23%), Positives = 42/76 (55%), Gaps = 5/76 (6%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275
++ Q +++REQ EK++ E+K +++++G + EE+ R Q+E+M +
Sbjct: 654 KMREQEEKMREQ-----EEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQE 708
Query: 276 QLEALQEERNTAEQDL 291
+ QEE+ ++++
Sbjct: 709 EKMWGQEEKMWGQEEM 724
Score = 29.6 bits (65), Expect = 4.2
Identities = 18/74 (24%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
+ +R+RE+ + E+ EQ+E++ + + K EE+ E+ ++ Q+++ + Q E
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 280 L---QEERNTAEQD 290
+ +EE EQ+
Sbjct: 618 MWEQEEEDKMQEQE 631
Score = 29.6 bits (65), Expect = 4.2
Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEE--EACEERQRWQQEQMVL 273
+++ Q + + EQ + ++ K EQ+E++ + + K EE + EE+ R Q+E+M
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685
Query: 274 RFQLEALQEERNTAEQD 290
+ + QEE+ +++
Sbjct: 686 QEEKMREQEEKMRGQEE 702
Score = 29.3 bits (64), Expect = 5.5
Identities = 20/114 (17%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Query: 177 WDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKL 236
WD E+ R + E+ + ++ ++ Q +++ EQ + ++
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 237 KHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQD 290
K EQ+E++ + + + + E +E W+QE+ + + + ++E EQ+
Sbjct: 610 KMWEQEEKMWEQEEEDKMQE----QEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/73 (30%), Positives = 47/73 (64%), Gaps = 3/73 (4%)
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEA-CEERQRWQQEQMVLRFQLE 278
Q +++REQ + IRE+ + + ++EE+ +Q + + +EE CE+ ++ Q+++ +R Q E
Sbjct: 583 QEEKIREQEEK-IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 279 ALQE-ERNTAEQD 290
++E E+ EQ+
Sbjct: 642 KIREQEKKIREQE 654
Score = 38.9 bits (89), Expect = 0.007
Identities = 26/135 (19%), Positives = 67/135 (49%), Gaps = 3/135 (2%)
Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLE-DTLTDSGLSQLGRALRELEAQRQRLRE 226
++++ +W E+ R + +R + E + +T ++G ++ Q ++++E
Sbjct: 572 KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE 631
Query: 227 QHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQR-WQQEQMVLRFQLEALQEERN 285
Q + R++ K EQ++++ + + K EE E+ ++ W+QE+ + Q E +QE+
Sbjct: 632 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE-QEEKMQEQEE 690
Query: 286 TAEQDLAALYDLHVQ 300
+ +++ V+
Sbjct: 691 KMRRQEEKMWEQEVR 705
Score = 38.9 bits (89), Expect = 0.007
Identities = 22/88 (25%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 216 ELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRF 275
++ Q +++REQ + ++ K EQ+E + + + K EE+ CE+ ++ Q+++ +R
Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694
Query: 276 QLEAL--QEERNTAEQDLAALYDLHVQA 301
Q E + QE R +++ + H++A
Sbjct: 695 QEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 38.5 bits (88), Expect = 0.009
Identities = 18/74 (24%), Positives = 43/74 (58%)
Query: 215 RELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLR 274
+++ Q +++REQ ++ ++ K EQ+E++ + + K EE+ + ++ ++++ LR
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707
Query: 275 FQLEALQEERNTAE 288
Q E +QE + E
Sbjct: 708 QQEEKMQEHQEHLE 721
Score = 36.6 bits (83), Expect = 0.034
Identities = 20/83 (24%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
++ R ++ Q +++R+Q + R++ K +Q+E++ + + K EE+ E+ ++ ++
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 269 EQMVLRFQLEALQE-ERNTAEQD 290
++ +R Q E QE E EQ+
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQE 619
Score = 34.3 bits (77), Expect = 0.17
Identities = 20/80 (25%), Positives = 45/80 (56%), Gaps = 1/80 (1%)
Query: 212 RALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQM 271
R E+ Q++++ EQ + +++ K Q+E++ D + K EE+ + ++ ++++
Sbjct: 533 REQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 272 VLRFQLEALQE-ERNTAEQD 290
+R Q E ++E E T EQ+
Sbjct: 593 KIREQEEKIREQEEMTQEQE 612
Score = 33.9 bits (76), Expect = 0.22
Identities = 28/131 (21%), Positives = 61/131 (46%), Gaps = 7/131 (5%)
Query: 166 RMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLR 225
++Q + LW+ + + + + + ++ E+ + + ++ ++ Q +++R
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE-EKIREQEEKIREQEEKMR 399
Query: 226 EQHQI-WIRE-KLKHLEQ----KEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q ++ W +E K++ E+ KEE Q + + +EE E + EQ +R Q E
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 280 LQEERNTAEQD 290
QEE EQ+
Sbjct: 460 RQEEEKIREQE 470
Score = 33.1 bits (74), Expect = 0.38
Identities = 22/113 (19%), Positives = 55/113 (48%), Gaps = 4/113 (3%)
Query: 197 LLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIR----EKLKHLEQKEEVADDQVKG 252
LL + LG+ L+ + A+ Q E++++W R ++ K Q+E++ + + K
Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377
Query: 253 LVAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQ 305
EE+ E+ ++ ++++ +R Q E + E+ + +++ + R +
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430
Score = 33.1 bits (74), Expect = 0.38
Identities = 24/85 (28%), Positives = 46/85 (54%), Gaps = 8/85 (9%)
Query: 212 RALRELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQR- 265
R L E +++++REQ + IRE+ K EQ+ ++ + K EE+ E+ ++
Sbjct: 441 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM 500
Query: 266 WQQEQMVLRFQLEALQEERNTAEQD 290
W+QE+ + + E ++EE EQ+
Sbjct: 501 WRQEEKI--HEQEKIREEEKRQEQE 523
Score = 32.7 bits (73), Expect = 0.49
Identities = 19/87 (21%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 208 SQLGRALRELEAQRQRLREQHQ-IWIREKLKHLEQK---EEVADDQVKGLVAEEEACEER 263
+++ R ++ Q +++REQ + +W +E+ H ++K EE +Q + EE+ E+
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 536
Query: 264 QRWQQEQMVLRFQLEALQEERNTAEQD 290
+ W+Q++ + + + ++E Q+
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Score = 30.8 bits (68), Expect = 1.9
Identities = 21/85 (24%), Positives = 45/85 (52%), Gaps = 10/85 (11%)
Query: 216 ELEAQRQRLREQHQIW-----IREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQ 270
++ Q +R ++ ++W IRE+ + + ++EE Q + + +E+ EE +R +QE+
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE 524
Query: 271 M-----VLRFQLEALQEERNTAEQD 290
M +R Q E +++ EQ+
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQE 549
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 39.7 bits (91), Expect = 0.004
Identities = 38/141 (26%), Positives = 66/141 (46%), Gaps = 6/141 (4%)
Query: 166 RMQVKQVRPTLWD---AVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQ 222
R QV Q+R L A ++ + L L + G + +L +LE+Q Q
Sbjct: 996 RDQVDQLRTELMQERSARQDLECDKISLERQNKDLKTRLASSEGFQKPSASLSQLESQNQ 1055
Query: 223 RLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEALQE 282
L+E+ Q REK L+ + +VK L + E +ERQ ++ L +++AL+
Sbjct: 1056 LLQERLQAEEREKTV-LQSTNRKLERKVKELSIQIE--DERQHVNDQKDQLSLRVKALKR 1112
Query: 283 ERNTAEQDLAALYDLHVQATR 303
+ + AE+++ L L +A R
Sbjct: 1113 QVDEAEEEIERLDGLRKKAQR 1133
Score = 32.7 bits (73), Expect = 0.49
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 40/210 (19%)
Query: 156 LLLRLDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQL----- 210
L LR++ + ++ + L +E+ARA R + + E T L +L
Sbjct: 590 LQLRMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQAERQ 649
Query: 211 -----GR----------ALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255
GR A+ +EA R R E+ + +++ L+ L Q E A +VA
Sbjct: 650 SQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDCEEASKAK--MVA 707
Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315
E EA QR + LR QEE + + + L + ++ TR
Sbjct: 708 EAEATVLGQRRAAVETTLR----ETQEENDEFRRRILGL-EQQLKETR------------ 750
Query: 316 GGLLAGTLEETINLATQNQELQAENQQLQQ 345
GL+ G L + Q L+AE QQL++
Sbjct: 751 -GLVDGGEAVEARLRDKLQRLEAEKQQLEE 779
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/131 (25%), Positives = 64/131 (48%), Gaps = 2/131 (1%)
Query: 160 LDPQGRRMQVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEA 219
L+ GR++Q + + + + R + RL E+ L + +L L
Sbjct: 173 LESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQE-ERLCEQEERLCE 231
Query: 220 QRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQLEA 279
Q +RLREQ + +RE+ + L ++EE +Q + L +EE E+++ ++ +L +
Sbjct: 232 QEERLREQEE-RLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKL 290
Query: 280 LQEERNTAEQD 290
L++ER EQ+
Sbjct: 291 LEQERRQEEQE 301
Score = 32.0 bits (71), Expect = 0.84
Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 15/91 (16%)
Query: 215 RELEAQRQRLR---EQHQIW----------IREKLKHLEQKEEVADDQVKGLVAEEE-AC 260
+ELE+ ++L+ E +Q+ +RE+ + L ++EE +Q + L +EE C
Sbjct: 171 KELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLC 230
Query: 261 EERQRWQQEQMVLRFQLEALQE-ERNTAEQD 290
E+ +R ++++ LR Q E L E E EQ+
Sbjct: 231 EQEERLREQEERLREQEERLHEQEERLCEQE 261
Score = 31.2 bits (69), Expect = 1.4
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 5/115 (4%)
Query: 181 EEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE-LEAQRQRLREQHQIWIREKLKHL 239
+E R L + L + + LS L R E L Q +RL EQ + + E+ + L
Sbjct: 164 DETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEER-LHEQEERL 222
Query: 240 EQKEEVADDQVKGLVAEEEAC---EERQRWQQEQMVLRFQLEALQEERNTAEQDL 291
++EE +Q + L +EE EER Q+E++ + + QEER ++ L
Sbjct: 223 CEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKL 277
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 38.9 bits (89), Expect = 0.007
Identities = 37/159 (23%), Positives = 75/159 (47%), Gaps = 13/159 (8%)
Query: 194 RLGLLEDTLTDS--GLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVK 251
+L L E +D+ ++ L R ++ +E + R +E+ + L+ LE+ E+ AD+ +
Sbjct: 70 KLELTEKKASDAEGDVAALNRRIQLVEEELDRAQER----LATALQKLEEAEKAADESER 125
Query: 252 GL-VAEEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVL 310
G+ V E A ++ ++ + ++M L+ +E E+ L L + RA+ +
Sbjct: 126 GMKVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEVARKLVILEGELERAEERAEV 185
Query: 311 PISGDGGLLAGTLEETINLATQN-QELQAENQQLQQGAD 348
L G LEE + T N + L+A +++ + D
Sbjct: 186 -----SELKCGDLEEELKNVTNNLKSLEAASEKYSEKED 219
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 38.9 bits (89), Expect = 0.007
Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 22/132 (16%)
Query: 163 QGRRMQVKQVRPT------LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216
QG+ VKQ+R LW VEE R R E+ + + S+ + L+
Sbjct: 1663 QGKEEAVKQLRKMQAQMKELWREVEETRTSR-----------EEIFSQNRESE--KRLKG 1709
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276
LEA+ RL+E+ R + + + ++E+AD+ G +++ EE+++ + L
Sbjct: 1710 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE-- 1767
Query: 277 LEALQEERNTAE 288
E L+EE++ +E
Sbjct: 1768 -EELEEEQSNSE 1778
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 16/140 (11%)
Query: 125 RVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEAR 184
R+L+G++V AE L +V + E + L +G ++VKQ++ L +A EEA
Sbjct: 1862 RILSGKLV-RRAEKRLKEVVLQVEEERRVADQLRDQLEKGN-LRVKQLKRQLEEAEEEAS 1919
Query: 185 ARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEE 244
+AG R L+ L + +T+S S RE+ R RLR + ++ + + EE
Sbjct: 1920 RAQAGRRRLQREL--EDVTESAESM----NREVTTLRNRLRRGPLTFTTRTVRQVFRLEE 1973
Query: 245 VADDQVKGLVAEEEACEERQ 264
G+ ++EEA EE Q
Sbjct: 1974 -------GVASDEEA-EEAQ 1985
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
QL + LR+ E +R R+Q + + + K + EE+ +EEA ++ ++ Q
Sbjct: 1618 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA 1677
Query: 269 EQMVLRFQLEALQEER 284
+ L ++E + R
Sbjct: 1678 QMKELWREVEETRTSR 1693
Score = 30.0 bits (66), Expect = 3.2
Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 198 LEDTLT--DSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255
+ED L + G +L + R L+ + L+EQ +EQ++ + + +
Sbjct: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQM----------VEQQQRAEELRAQLGRK 1113
Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315
EEE R + E L++L+E + + L V T+A+ + +
Sbjct: 1114 EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQR-RDLGEE 1172
Query: 316 GGLLAGTLEETINLATQNQELQAENQQ 342
L G LE+T++ QEL+++ +Q
Sbjct: 1173 LEALRGELEDTLDSTNAQQELRSKREQ 1199
Score = 28.5 bits (62), Expect = 9.3
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 17/138 (12%)
Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227
Q++++R L + ARAR + + LE L + QL + RE + +R
Sbjct: 1818 QIQELRGRLGEEDAGARARHK----MTIAALESKLAQAE-EQLEQETRERILSGKLVRRA 1872
Query: 228 HQIWIREKLKHLEQKEEVADD----------QVKGLVAE-EEACEERQRWQQEQMVLRFQ 276
+ ++E + +E++ VAD +VK L + EEA EE R Q + L+ +
Sbjct: 1873 EKR-LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1931
Query: 277 LEALQEERNTAEQDLAAL 294
LE + E + +++ L
Sbjct: 1932 LEDVTESAESMNREVTTL 1949
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 38.9 bits (89), Expect = 0.007
Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 22/132 (16%)
Query: 163 QGRRMQVKQVRPT------LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216
QG+ VKQ+R LW VEE R R E+ + + S+ + L+
Sbjct: 1655 QGKEEAVKQLRKMQAQMKELWREVEETRTSR-----------EEIFSQNRESE--KRLKG 1701
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276
LEA+ RL+E+ R + + + ++E+AD+ G +++ EE+++ + L
Sbjct: 1702 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE-- 1759
Query: 277 LEALQEERNTAE 288
E L+EE++ +E
Sbjct: 1760 -EELEEEQSNSE 1770
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 16/140 (11%)
Query: 125 RVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEAR 184
R+L+G++V AE L +V + E + L +G ++VKQ++ L +A EEA
Sbjct: 1854 RILSGKLV-RRAEKRLKEVVLQVEEERRVADQLRDQLEKGN-LRVKQLKRQLEEAEEEAS 1911
Query: 185 ARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEE 244
+AG R L+ L + +T+S S RE+ R RLR + ++ + + EE
Sbjct: 1912 RAQAGRRRLQREL--EDVTESAESM----NREVTTLRNRLRRGPLTFTTRTVRQVFRLEE 1965
Query: 245 VADDQVKGLVAEEEACEERQ 264
G+ ++EEA EE Q
Sbjct: 1966 -------GVASDEEA-EEAQ 1977
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
QL + LR+ E +R R+Q + + + K + EE+ +EEA ++ ++ Q
Sbjct: 1610 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA 1669
Query: 269 EQMVLRFQLEALQEER 284
+ L ++E + R
Sbjct: 1670 QMKELWREVEETRTSR 1685
Score = 30.0 bits (66), Expect = 3.2
Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 198 LEDTLT--DSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255
+ED L + G +L + R L+ + L+EQ +EQ++ + + +
Sbjct: 1056 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQM----------VEQQQRAEELRAQLGRK 1105
Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315
EEE R + E L++L+E + + L V T+A+ + +
Sbjct: 1106 EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQR-RDLGEE 1164
Query: 316 GGLLAGTLEETINLATQNQELQAENQQ 342
L G LE+T++ QEL+++ +Q
Sbjct: 1165 LEALRGELEDTLDSTNAQQELRSKREQ 1191
Score = 28.5 bits (62), Expect = 9.3
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 17/138 (12%)
Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227
Q++++R L + ARAR + + LE L + QL + RE + +R
Sbjct: 1810 QIQELRGRLGEEDAGARARHK----MTIAALESKLAQAE-EQLEQETRERILSGKLVRRA 1864
Query: 228 HQIWIREKLKHLEQKEEVADD----------QVKGLVAE-EEACEERQRWQQEQMVLRFQ 276
+ ++E + +E++ VAD +VK L + EEA EE R Q + L+ +
Sbjct: 1865 EKR-LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1923
Query: 277 LEALQEERNTAEQDLAAL 294
LE + E + +++ L
Sbjct: 1924 LEDVTESAESMNREVTTL 1941
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 38.9 bits (89), Expect = 0.007
Identities = 35/132 (26%), Positives = 64/132 (48%), Gaps = 22/132 (16%)
Query: 163 QGRRMQVKQVRPT------LWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRE 216
QG+ VKQ+R LW VEE R R E+ + + S+ + L+
Sbjct: 1696 QGKEEAVKQLRKMQAQMKELWREVEETRTSR-----------EEIFSQNRESE--KRLKG 1742
Query: 217 LEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQEQMVLRFQ 276
LEA+ RL+E+ R + + + ++E+AD+ G +++ EE+++ + L
Sbjct: 1743 LEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE-- 1800
Query: 277 LEALQEERNTAE 288
E L+EE++ +E
Sbjct: 1801 -EELEEEQSNSE 1811
Score = 34.3 bits (77), Expect = 0.17
Identities = 42/140 (30%), Positives = 69/140 (49%), Gaps = 16/140 (11%)
Query: 125 RVLAGEVVGEEAEGSLPWIVSWLLEGNNYSGLLLRLDPQGRRMQVKQVRPTLWDAVEEAR 184
R+L+G++V AE L +V + E + L +G ++VKQ++ L +A EEA
Sbjct: 1895 RILSGKLV-RRAEKRLKEVVLQVEEERRVADQLRDQLEKGN-LRVKQLKRQLEEAEEEAS 1952
Query: 185 ARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEE 244
+AG R L+ L + +T+S S RE+ R RLR + ++ + + EE
Sbjct: 1953 RAQAGRRRLQREL--EDVTESAESM----NREVTTLRNRLRRGPLTFTTRTVRQVFRLEE 2006
Query: 245 VADDQVKGLVAEEEACEERQ 264
G+ ++EEA EE Q
Sbjct: 2007 -------GVASDEEA-EEAQ 2018
Score = 30.4 bits (67), Expect = 2.5
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 209 QLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVAEEEACEERQRWQQ 268
QL + LR+ E +R R+Q + + + K + EE+ +EEA ++ ++ Q
Sbjct: 1651 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQA 1710
Query: 269 EQMVLRFQLEALQEER 284
+ L ++E + R
Sbjct: 1711 QMKELWREVEETRTSR 1726
Score = 30.0 bits (66), Expect = 3.2
Identities = 33/147 (22%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 198 LEDTLT--DSGLSQLGRALRELEAQRQRLREQHQIWIREKLKHLEQKEEVADDQVKGLVA 255
+ED L + G +L + R L+ + L+EQ +EQ++ + + +
Sbjct: 1097 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQM----------VEQQQRAEELRAQLGRK 1146
Query: 256 EEEACEERQRWQQEQMVLRFQLEALQEERNTAEQDLAALYDLHVQATRAQTHHVLPISGD 315
EEE R + E L++L+E + + L V T+A+ + +
Sbjct: 1147 EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQR-RDLGEE 1205
Query: 316 GGLLAGTLEETINLATQNQELQAENQQ 342
L G LE+T++ QEL+++ +Q
Sbjct: 1206 LEALRGELEDTLDSTNAQQELRSKREQ 1232
Score = 28.5 bits (62), Expect = 9.3
Identities = 35/138 (25%), Positives = 63/138 (45%), Gaps = 17/138 (12%)
Query: 168 QVKQVRPTLWDAVEEARARRAGLRPLRLGLLEDTLTDSGLSQLGRALRELEAQRQRLREQ 227
Q++++R L + ARAR + + LE L + QL + RE + +R
Sbjct: 1851 QIQELRGRLGEEDAGARARHK----MTIAALESKLAQAE-EQLEQETRERILSGKLVRRA 1905
Query: 228 HQIWIREKLKHLEQKEEVADD----------QVKGLVAE-EEACEERQRWQQEQMVLRFQ 276
+ ++E + +E++ VAD +VK L + EEA EE R Q + L+ +
Sbjct: 1906 EKR-LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRE 1964
Query: 277 LEALQEERNTAEQDLAAL 294
LE + E + +++ L
Sbjct: 1965 LEDVTESAESMNREVTTL 1982
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,236,479
Number of Sequences: 37866
Number of extensions: 715120
Number of successful extensions: 5055
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 315
Number of HSP's that attempted gapping in prelim test: 3129
Number of HSP's gapped (non-prelim): 1545
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.