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Search of human proteins with 239747109
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
sapiens]
(146 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo ... 288 1e-78
gi|169178850 PREDICTED: similar to coiled-coil domain containing... 257 2e-69
gi|169217383 PREDICTED: similar to coiled-coil domain containing... 242 7e-65
gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens] 241 1e-64
gi|149363632 coiled-coil domain containing 29 [Homo sapiens] 227 3e-60
gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo ... 226 5e-60
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 217 3e-57
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 217 3e-57
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 217 3e-57
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 211 2e-55
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 211 2e-55
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 211 2e-55
gi|239742325 PREDICTED: similar to coiled-coil domain containing... 176 6e-45
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 168 1e-42
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 147 3e-36
gi|169169660 PREDICTED: hypothetical protein [Homo sapiens] 106 8e-24
gi|169169929 PREDICTED: hypothetical protein [Homo sapiens] 106 8e-24
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 82 2e-16
gi|50083279 centrosome protein 4 [Homo sapiens] 50 7e-07
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 49 2e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 49 2e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 49 2e-06
gi|71061468 centromere protein E [Homo sapiens] 47 6e-06
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 45 2e-05
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 45 2e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 45 3e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 45 3e-05
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 44 5e-05
gi|156546890 WW and C2 domain containing 2 [Homo sapiens] 44 6e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 43 1e-04
>gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
sapiens]
Length = 146
Score = 288 bits (737), Expect = 1e-78
Identities = 146/146 (100%), Positives = 146/146 (100%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ
Sbjct: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
Query: 121 AVEKLKEIHLQVTCLNQSNDSHYGVI 146
AVEKLKEIHLQVTCLNQSNDSHYGVI
Sbjct: 121 AVEKLKEIHLQVTCLNQSNDSHYGVI 146
>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 197
Score = 257 bits (657), Expect = 2e-69
Identities = 133/139 (95%), Positives = 135/139 (97%), Gaps = 2/139 (1%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ
Sbjct: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
Query: 121 AVEKLKEIHLQ--VTCLNQ 137
AVEKLKEIHLQ + C+ Q
Sbjct: 121 AVEKLKEIHLQMELDCVEQ 139
>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 185
Score = 242 bits (618), Expect = 7e-65
Identities = 124/139 (89%), Positives = 132/139 (94%), Gaps = 2/139 (1%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDL EEEAVSSKCVNL+KDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
VIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTHMEN+MVELSKLQEYKSE DERA+Q
Sbjct: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
Query: 121 AVEKLKEIHLQV--TCLNQ 137
AVEKL+EIHLQ+ C+ Q
Sbjct: 121 AVEKLEEIHLQMEADCVEQ 139
>gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]
Length = 154
Score = 241 bits (616), Expect = 1e-64
Identities = 124/139 (89%), Positives = 132/139 (94%), Gaps = 2/139 (1%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDL EEEAVSSKCVNL+KDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
VIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTHMEN+MVELSKLQEYKSE DERA+Q
Sbjct: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSEPDERAIQ 120
Query: 121 AVEKLKEIHLQV--TCLNQ 137
AVEKL+EIHLQ+ C+ Q
Sbjct: 121 AVEKLEEIHLQMEADCVEQ 139
>gi|149363632 coiled-coil domain containing 29 [Homo sapiens]
Length = 161
Score = 227 bits (578), Expect = 3e-60
Identities = 114/139 (82%), Positives = 129/139 (92%), Gaps = 2/139 (1%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLNVFGNEDF CH DLKTDQLKMDILIKKLKQKFDDL A++EA+SSKCVNL+KDNQ
Sbjct: 1 MTINMLNVFGNEDFDCHGDLKTDQLKMDILIKKLKQKFDDLTAQKEALSSKCVNLAKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTHMEN+ VE+SKLQEYK ELDE+AMQ
Sbjct: 61 VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVEISKLQEYKLELDEKAMQ 120
Query: 121 AVEKLKEIHLQ--VTCLNQ 137
AVEKL+EIHLQ + C+ Q
Sbjct: 121 AVEKLEEIHLQMELDCVEQ 139
>gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo
sapiens]
Length = 183
Score = 226 bits (576), Expect = 5e-60
Identities = 114/139 (82%), Positives = 128/139 (92%), Gaps = 2/139 (1%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDL AE+EA+SSKCVNL+KDNQ
Sbjct: 23 MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+QQE LSMKKVQQ+CEKLEE++KML+EEILNLKTHMEN+ VELSKLQEYK ELDE+AMQ
Sbjct: 83 VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
Query: 121 AVEKLKEIHLQ--VTCLNQ 137
AVEK++EIHLQ + C+ Q
Sbjct: 143 AVEKIEEIHLQMELDCVEQ 161
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 217 bits (552), Expect = 3e-57
Identities = 106/131 (80%), Positives = 120/131 (91%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDLMAE+EAVSSKCVNL+KDN+
Sbjct: 821 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 880
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTHME MVEL K+QEYKSELDERAMQ
Sbjct: 881 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 940
Query: 121 AVEKLKEIHLQ 131
A+EKL+EIHLQ
Sbjct: 941 AIEKLEEIHLQ 951
Score = 31.6 bits (70), Expect = 0.25
Identities = 28/126 (22%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D ++ K D + K D M +EE + K +L K+ + I QE+ S+ ++ E
Sbjct: 420 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 478
Query: 78 K-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE-KLKEIHLQV-TC 134
K + N++M+ +++ + + E ++L K E ++ + +E +++ +H + T
Sbjct: 479 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNS-KLEKEKHNKERLEAEVESLHSNLATA 537
Query: 135 LNQSND 140
+N+ N+
Sbjct: 538 INEYNE 543
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 217 bits (552), Expect = 3e-57
Identities = 106/131 (80%), Positives = 120/131 (91%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDLMAE+EAVSSKCVNL+KDN+
Sbjct: 850 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTHME MVEL K+QEYKSELDERAMQ
Sbjct: 910 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 969
Query: 121 AVEKLKEIHLQ 131
A+EKL+EIHLQ
Sbjct: 970 AIEKLEEIHLQ 980
Score = 31.6 bits (70), Expect = 0.25
Identities = 28/126 (22%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D ++ K D + K D M +EE + K +L K+ + I QE+ S+ ++ E
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 507
Query: 78 K-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE-KLKEIHLQV-TC 134
K + N++M+ +++ + + E ++L K E ++ + +E +++ +H + T
Sbjct: 508 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNS-KLEKEKHNKERLEAEVESLHSNLATA 566
Query: 135 LNQSND 140
+N+ N+
Sbjct: 567 INEYNE 572
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 217 bits (552), Expect = 3e-57
Identities = 106/131 (80%), Positives = 120/131 (91%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDLMAE+EAVSSKCVNL+KDN+
Sbjct: 850 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+ QELLSM KVQ++CEKLE+++KMLEE++LNLKTHME MVEL K+QEYKSELDERAMQ
Sbjct: 910 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 969
Query: 121 AVEKLKEIHLQ 131
A+EKL+EIHLQ
Sbjct: 970 AIEKLEEIHLQ 980
Score = 31.6 bits (70), Expect = 0.25
Identities = 28/126 (22%), Positives = 64/126 (50%), Gaps = 5/126 (3%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D ++ K D + K D M +EE + K +L K+ + I QE+ S+ ++ E
Sbjct: 449 QDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 507
Query: 78 K-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE-KLKEIHLQV-TC 134
K + N++M+ +++ + + E ++L K E ++ + +E +++ +H + T
Sbjct: 508 KSVRLNEEMITKKVAQYSQQLNDLKAENARLNS-KLEKEKHNKERLEAEVESLHSNLATA 566
Query: 135 LNQSND 140
+N+ N+
Sbjct: 567 INEYNE 572
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 211 bits (536), Expect = 2e-55
Identities = 102/131 (77%), Positives = 119/131 (90%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL+AE+EAVSS+CVNL+KDN+
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTHME MVEL KLQEYKSELDERA+Q
Sbjct: 880 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 939
Query: 121 AVEKLKEIHLQ 131
+EKL+EIHLQ
Sbjct: 940 EIEKLEEIHLQ 950
Score = 32.0 bits (71), Expect = 0.19
Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D ++ K D + K D M +EE + K +L K+ + I QE+ S+ ++ E
Sbjct: 419 QDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 477
Query: 78 K-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV-TCL 135
K + N+KM+ + + + + E ++L + + +++ +H + T +
Sbjct: 478 KSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAI 537
Query: 136 NQSND 140
N+ N+
Sbjct: 538 NEYNE 542
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 211 bits (536), Expect = 2e-55
Identities = 102/131 (77%), Positives = 119/131 (90%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL+AE+EAVSS+CVNL+KDN+
Sbjct: 713 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 772
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTHME MVEL KLQEYKSELDERA+Q
Sbjct: 773 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 832
Query: 121 AVEKLKEIHLQ 131
+EKL+EIHLQ
Sbjct: 833 EIEKLEEIHLQ 843
Score = 32.0 bits (71), Expect = 0.19
Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D ++ K D + K D M +EE + K +L K+ + I QE+ S+ ++ E
Sbjct: 312 QDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 370
Query: 78 K-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV-TCL 135
K + N+KM+ + + + + E ++L + + +++ +H + T +
Sbjct: 371 KSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAI 430
Query: 136 NQSND 140
N+ N+
Sbjct: 431 NEYNE 435
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 211 bits (536), Expect = 2e-55
Identities = 102/131 (77%), Positives = 119/131 (90%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL+AE+EAVSS+CVNL+KDN+
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
V+ QELLSM+ VQ++CEKLE+++KMLEEE+LNLKTHME MVEL KLQEYKSELDERA+Q
Sbjct: 880 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 939
Query: 121 AVEKLKEIHLQ 131
+EKL+EIHLQ
Sbjct: 940 EIEKLEEIHLQ 950
Score = 32.0 bits (71), Expect = 0.19
Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 3/125 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D ++ K D + K D M +EE + K +L K+ + I QE+ S+ ++ E
Sbjct: 419 QDSQSYGKKKDAMYGNFMLKKDIAMLKEELYAIKNDSLRKEKKYI-QEIKSITEINANFE 477
Query: 78 K-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV-TCL 135
K + N+KM+ + + + + E ++L + + +++ +H + T +
Sbjct: 478 KSVRLNEKMITKTVARYSQQLNDLKAENARLNSELEKEKHNKERLEAEVESLHSSLATAI 537
Query: 136 NQSND 140
N+ N+
Sbjct: 538 NEYNE 542
>gi|239742325 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 150
Score = 176 bits (446), Expect = 6e-45
Identities = 90/103 (87%), Positives = 98/103 (95%), Gaps = 2/103 (1%)
Query: 37 KFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 96
+FDDLMAEEEAVSSKCVNL+KDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH
Sbjct: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
Query: 97 MENSMVELSKLQEYKSELDERAMQAVEKLKEI--HLQVTCLNQ 137
MENS+VELS+LQ+YKSELDERAMQAVEKLKEI H++ C+ Q
Sbjct: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQ 104
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 168 bits (426), Expect = 1e-42
Identities = 85/99 (85%), Positives = 95/99 (95%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
+++ +FDD MAE+EAVSSKCVNL+K+ QV QQELLSMKKVQQECEKLEE++KMLEEEILN
Sbjct: 443 QVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILN 502
Query: 93 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
LKTHMENSMVELSKLQEYKSELDERAMQAVEKL+EIHLQ
Sbjct: 503 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQ 541
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 147 bits (371), Expect = 3e-36
Identities = 74/142 (52%), Positives = 104/142 (73%), Gaps = 3/142 (2%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
MT LN + N +F H DLKT Q +MDI I KLK K DDL AE E SKC++L NQ
Sbjct: 1369 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1428
Query: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
++Q+ELLSMK VQ++CEKL++N+K LE+E++NL++H+E +MVEL ++++YK E++ERA Q
Sbjct: 1429 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1488
Query: 121 AV-EKLKEIH--LQVTCLNQSN 139
+ EKLKE++ LQ +Q N
Sbjct: 1489 EIAEKLKEVNLFLQAQAASQEN 1510
Score = 33.5 bits (75), Expect = 0.066
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 11/122 (9%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC---EKLEENQKMLE 87
+K+ KQ+ ++ +E A K VNL Q QE L + ++E K LE
Sbjct: 1475 VKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLE 1534
Query: 88 EEILNLKTHMEN-SMVELSK-----LQEYK--SELDERAMQAVEKLKEIHLQVTCLNQSN 139
E+ +KT E+ + EL K L+E K L + + E+L E++ ++ Q +
Sbjct: 1535 SELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQS 1594
Query: 140 DS 141
S
Sbjct: 1595 RS 1596
Score = 31.2 bits (69), Expect = 0.33
Identities = 27/129 (20%), Positives = 62/129 (48%), Gaps = 14/129 (10%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQE 75
C EDLK + K + L K +KQ + L + + L+ +N ++ +L
Sbjct: 942 CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKL--------- 992
Query: 76 CEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELD---ERAMQAVEKLKE-IHLQ 131
E +++++ LE E+ + + + ++ + + + K EL+ +RA +L++ ++
Sbjct: 993 -ENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFD 1051
Query: 132 VTCLNQSND 140
V+ L +N+
Sbjct: 1052 VSNLKDNNE 1060
Score = 30.4 bits (67), Expect = 0.56
Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 11/116 (9%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+DLK ++ +++ + + + + E + L KDN ++ V+++ +
Sbjct: 1257 QDLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLK------VTVKKQMD 1310
Query: 78 KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVT 133
K+EE QK L L+ E+ +L KL E K L+ Q ++K E+ ++T
Sbjct: 1311 KIEELQKNLLNANLS-----EDEKEQLKKLMELKQSLECNLDQEMKKNVELEREIT 1361
Score = 27.7 bits (60), Expect = 3.6
Identities = 23/93 (24%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 24 QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE-KLEEN 82
Q ++++ KK+ + EE+ +S K L ++ +++ E+ ++K QE E K E+
Sbjct: 886 QKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFED 945
Query: 83 QKMLEEEILNL-KTHMENSMVELSKLQEYKSEL 114
K+++E+ +L KT +N + +Y L
Sbjct: 946 LKIVKEKNEDLQKTIKQNEETLTQTISQYNGRL 978
>gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 106 bits (264), Expect = 8e-24
Identities = 56/105 (53%), Positives = 78/105 (74%), Gaps = 1/105 (0%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEIL 91
K L++ +L + KC+ L+K NQVIQQELLSMK+VQQ+C+KLEE K+LE+E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375
Query: 92 NLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLN 136
NLKTH E +MVE ++E K +L+ERA Q +EKL+EI+LQ CL+
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQRACLS 419
>gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 106 bits (264), Expect = 8e-24
Identities = 56/105 (53%), Positives = 78/105 (74%), Gaps = 1/105 (0%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEIL 91
K L++ +L + KC+ L+K NQVIQQELLSMK+VQQ+C+KLEE K+LE+E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375
Query: 92 NLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLN 136
NLKTH E +MVE ++E K +L+ERA Q +EKL+EI+LQ CL+
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQRACLS 419
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 81.6 bits (200), Expect = 2e-16
Identities = 47/120 (39%), Positives = 78/120 (65%), Gaps = 5/120 (4%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQ--QELLSMKKVQQECEKLEENQ 83
+MD K+ + DL +E V S+C++L +N+V+Q Q L SMK +Q++CE L++N+
Sbjct: 1112 RMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNK 1171
Query: 84 KMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAV-EKLKEIHLQVTCLNQSNDSH 142
K L++E++NLK++ME +M+E K + +K ++ERA + + EKL E L T Q+ SH
Sbjct: 1172 KQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAIL--TLQKQAAVSH 1229
Score = 33.9 bits (76), Expect = 0.050
Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL-SM 69
+ED + E++ +L++D + + KQK + EAV K NL K ++ ++ L ++
Sbjct: 819 HEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETI 878
Query: 70 KKVQQECEKLEENQKMLEEEILNLKTHMENSMVEL 104
+ + L K+L E+ N K + E +E+
Sbjct: 879 LQYSGQLNNLTAENKILNSELENGKQNQERLEIEM 913
Score = 28.5 bits (62), Expect = 2.1
Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 21/136 (15%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
ED++ + K D L K +K + L S + NL+ +N+++ EL + K+ Q+ E
Sbjct: 851 EDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGKQNQERLE 910
Query: 78 ---------------KLEENQKMLEEEILNLKTHME------NSMVELSKLQEYKSELDE 116
+++Q + ++ +T E V++S LQ L E
Sbjct: 911 IEMESYRCRLAAAVRDCDQSQTARDLKLDFQRTRQEWVRLHDKMKVDMSGLQAKNEILSE 970
Query: 117 RAMQAVEKLKEIHLQV 132
+ A K+ + +Q+
Sbjct: 971 KLSNAESKINSLQIQL 986
Score = 28.5 bits (62), Expect = 2.1
Identities = 18/81 (22%), Positives = 40/81 (49%), Gaps = 1/81 (1%)
Query: 60 QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAM 119
Q+ Q E +KK + E +EE L+ E + L+ ++++ + + ++ S + ++
Sbjct: 1019 QMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANSQEKTSSTIQDQFH 1078
Query: 120 QAVEKLK-EIHLQVTCLNQSN 139
A + L+ E Q+ L + N
Sbjct: 1079 SAAKNLQAESEKQILSLQEKN 1099
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 50.1 bits (118), Expect = 7e-07
Identities = 33/118 (27%), Positives = 66/118 (55%), Gaps = 4/118 (3%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK 70
NE + H +++ D L+ K L+++ +LM +E V+S+ VNLS N+ + QEL +
Sbjct: 266 NEKLIAHLNIQVDFLQQ--ANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEID 323
Query: 71 KVQQECEK-LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKE 127
++ Q+ E+ EE + ++E+ K ++ + E+ L+E ++L + + +K KE
Sbjct: 324 QLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKL-QLELNLCQKEKE 380
Score = 30.8 bits (68), Expect = 0.43
Identities = 19/112 (16%), Positives = 54/112 (48%)
Query: 30 LIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEE 89
++++ ++ +D+ + + ++++ LS Q+EL +++K + ++E+E
Sbjct: 511 MLERFEKYMEDIQSNVKLLTAERDKLSVLYNEAQEELSALRKESTQTTAPHNIVSLMEKE 570
Query: 90 ILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDS 141
+ + M E L+E ++E ++ +L++ +TC+N +S
Sbjct: 571 KELALSDLRRIMAEKEALREKLEHIEEVSLFGKSELEKTIEHLTCVNHQLES 622
Score = 30.8 bits (68), Expect = 0.43
Identities = 23/110 (20%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKL 79
LK + D I L+++ D E + V K+N+ +Q +L +M + QE L
Sbjct: 781 LKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEI-SL 839
Query: 80 EENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIH 129
E + E+E +K+ + + E+S+ + + ++ +++ + +H
Sbjct: 840 ELEAAVQEKE--EMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLH 887
Score = 28.1 bits (61), Expect = 2.8
Identities = 19/97 (19%), Positives = 49/97 (50%), Gaps = 10/97 (10%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE-------LLSMKKVQQECEK 78
++++L K++++ + A E +SS +S+ + ++ + L + +++ C K
Sbjct: 924 RVELLEKEIQEHINAHHAYESQISSMAKAMSRLEEELRHQEDEKATVLNDLSSLRELCIK 983
Query: 79 LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELD 115
L+ + ++ +++ + E +VE L+ KSE D
Sbjct: 984 LDSGKDIMTQQLNSKNLEFERVVVE---LENVKSESD 1017
Score = 27.7 bits (60), Expect = 3.6
Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 18/115 (15%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKK----VQQECEKLEENQKML 86
IK L++K D+L NL +Q +E MKK + +E + L+E
Sbjct: 701 IKILEEKIDEL------------NLKMTSQ--DEEAHVMKKTIGVIDKEKDFLQETVDEK 746
Query: 87 EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDS 141
E+I NL+ ++ N +++++ SE + Q E L ++ L + D+
Sbjct: 747 TEKIANLQENLANKEKAVAQMKIMISECESSVNQLKETLVNRDREINSLRRQLDA 801
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 48.9 bits (115), Expect = 2e-06
Identities = 33/113 (29%), Positives = 61/113 (53%), Gaps = 4/113 (3%)
Query: 30 LIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL-SMKKVQQECEKLEENQKMLEE 88
+IK L ++ D L+ E+ +C++L K+N ++QE+ S+ K+ ++LE++ +
Sbjct: 70 IIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVK 129
Query: 89 EILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDS 141
EI NLK + M SK E K+ L ++ +A+ E+ Q+ N S D+
Sbjct: 130 EIENLKNEL---MAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDN 179
Score = 36.2 bits (82), Expect = 0.010
Identities = 29/127 (22%), Positives = 56/127 (44%), Gaps = 13/127 (10%)
Query: 17 HEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC 76
H++L+ + +K+++ ++LMA S NL K + L + + +
Sbjct: 117 HKELEQSHINY---VKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQ 173
Query: 77 EKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLN 136
E+N K L+EEI ++ E ++ L K +LD ++ KE Q+ +
Sbjct: 174 NNSEDNVKKLQEEIEKIRPGFEEQILYLQK------QLD----ATTDEKKETVTQLQNII 223
Query: 137 QSNDSHY 143
++N HY
Sbjct: 224 EANSQHY 230
Score = 32.3 bits (72), Expect = 0.15
Identities = 24/117 (20%), Positives = 48/117 (41%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
++ + ++K K++ M E E V + N I MK++ Q+ +
Sbjct: 1126 ELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIED 1185
Query: 86 LEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDSH 142
LE+EI K E E++ LQ + +E+ + + L + ++ Q+ H
Sbjct: 1186 LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDH 1242
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 48.9 bits (115), Expect = 2e-06
Identities = 35/140 (25%), Positives = 70/140 (50%), Gaps = 12/140 (8%)
Query: 12 EDFVCHEDLKTDQLKMDIL------IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE 65
E+ + HE +K K+ + IKK + + + E + ++ +L K+N+++Q++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 66 LLSMKKVQQECEKLEENQKMLEEEILNLKTHME---NSMVELSKLQEYKSELDERAMQA- 121
+ ++K ++ E LE+ LE E LK ++ N +L L++ S+LDE ++
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 122 --VEKLKEIHLQVTCLNQSN 139
VE LK +++ L N
Sbjct: 708 RNVESLKCASMKMAQLQLEN 727
Score = 38.1 bits (87), Expect = 0.003
Identities = 23/103 (22%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
E L+ +DI ++L++ ++ + + + S+ +L +NQ +Q+ L +K + E
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811
Query: 78 KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
+LE+ K LE+E L+ + E +L++ ++E+ + ++
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKDTTLE 853
Score = 34.7 bits (78), Expect = 0.029
Identities = 27/122 (22%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 24 QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQ 83
Q+ + +K ++++ L + SSK + + + I++EL K+ + E+LE
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634
Query: 84 KMLEE--EILNLK-THMENSMVELSKLQEYKSELD---ERAMQAVEKLKEIHLQVTCLNQ 137
LE+ E+L K T+++ + ++ L++ SEL+ + + ++ K + Q+ L +
Sbjct: 635 HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEK 694
Query: 138 SN 139
N
Sbjct: 695 EN 696
Score = 34.7 bits (78), Expect = 0.029
Identities = 30/112 (26%), Positives = 64/112 (57%), Gaps = 9/112 (8%)
Query: 20 LKTDQLKMDILIKKLKQKFD--DLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
L+ D+ +++ K+L+Q+ + D EE V K NL K+N+ + +E+ K+ +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNV--KIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 78 KLE-ENQKMLEEEILNLKTHM---ENSMVELSKLQEYKSELDERAMQAVEKL 125
+LE EN+++++ +++KT + E+ + E K Q+ ++L E+ +EK+
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELEKI 935
Score = 33.5 bits (75), Expect = 0.066
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 19/133 (14%)
Query: 25 LKMDILIKKLKQKFDDLMAEEEAV---SSKCVNLSKDNQ-------VIQQELLSMKKVQQ 74
LK+++ + L + ++L ++V +SK + + K+NQ +++ E++ K+ Q
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522
Query: 75 ECEKLEEN----QKMLEEEILNLKTHMENSMVELSK----LQEYKSELDERAMQAVE-KL 125
C+ L ++ + LE+ I L+ + E + L + L + S L +R+ + E ++
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV 582
Query: 126 KEIHLQVTCLNQS 138
K+I + L++S
Sbjct: 583 KDIEKENKILHES 595
Score = 33.5 bits (75), Expect = 0.066
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 14/130 (10%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
E L+TD + L+ K + L AE SK + QQ ++ K+ +CE
Sbjct: 1262 EVLQTDHKNLKSLLNNSKLEQTRLEAE----------FSKLKEQYQQLDITSTKLNNQCE 1311
Query: 78 KLEENQKMLEEEILNLKTHMENSMVE----LSKLQEYKSELDERAMQAVEKLKEIHLQVT 133
L + + LEEE +L ++ M++ L + E K Q ++KL E+ Q
Sbjct: 1312 LLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKE 1371
Query: 134 CLNQSNDSHY 143
L + Y
Sbjct: 1372 KLEEKIMDQY 1381
Score = 32.7 bits (73), Expect = 0.11
Identities = 19/81 (23%), Positives = 45/81 (55%), Gaps = 4/81 (4%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFD-DLMAEEEAVSSKCVNLSKD---NQVIQQEL 66
N++ + H++ TD + +L KL+ L +EE +++ L + NQ ++QEL
Sbjct: 938 NKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 997
Query: 67 LSMKKVQQECEKLEENQKMLE 87
++KK + ++ ++ ++M++
Sbjct: 998 KTVKKNYEALKQRQDEERMVQ 1018
Score = 31.6 bits (70), Expect = 0.25
Identities = 27/127 (21%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ--- 74
E L+ + ++D +L++ + L + S K L +N+ ++ E +KK +
Sbjct: 690 ESLEKENSQLDEENLELRRNVESL----KCASMKMAQLQLENKELESEKEQLKKGLELLK 745
Query: 75 ----ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHL 130
+ E+LE + + L+ E L+ +ENS ++ +L+ +L+ + L+E+ +
Sbjct: 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKI 805
Query: 131 QVTCLNQ 137
L Q
Sbjct: 806 SSKRLEQ 812
Score = 30.4 bits (67), Expect = 0.56
Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI 90
+KK F +L + E++ + L ++N +++ + S+K + +L+ K LE E
Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 91 LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQS 138
LK + EL K K+E E + Q ++ ++ LQ T N +
Sbjct: 735 EQLKKGL-----ELLKASFKKTERLEVSYQGLD-IENQRLQKTLENSN 776
Score = 30.4 bits (67), Expect = 0.56
Identities = 20/113 (17%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM----LEE 88
K +++ + E V + + + ++N +Q E ++K ++ E N + L+
Sbjct: 1029 KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR 1088
Query: 89 EILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDS 141
+ ++L+ + +KLQ S L+ ++ + + ++ +Q + L N+S
Sbjct: 1089 QTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENES 1141
Score = 28.9 bits (63), Expect = 1.6
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 26 KMDILIKKLKQKFDDLMAEE---EAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEEN 82
+++ L K LK + + ++ E E V+++ L +N + + K E E L+ +
Sbjct: 1211 QLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK---ETEVLQTD 1267
Query: 83 QKMLEEEILNLKTHMENSMVELSKLQEYKSELD 115
K L+ + N K E SKL+E +LD
Sbjct: 1268 HKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLD 1300
Score = 27.3 bits (59), Expect = 4.7
Identities = 20/94 (21%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
K++ + + K++ D+ E ++ L +DNQV+ + ++ + +
Sbjct: 324 KLESEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Query: 86 LEEEILNLKTHMENSMVELSKLQEYKSELDERAM 119
LE+E L LK + + +E ++ EL E M
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Score = 26.6 bits (57), Expect = 8.0
Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 56 SKDNQVIQQELLSMK-KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSEL 114
++ Q + EL K K+++ ++LEE E++L+ K +E +EL +LQ+ L
Sbjct: 243 TESRQHLSVELADAKAKIRRLRQELEEKT----EQLLDCKQELEQMEIELKRLQQENMNL 298
Query: 115 DERAMQA 121
A A
Sbjct: 299 LSDARSA 305
Score = 26.6 bits (57), Expect = 8.0
Identities = 16/73 (21%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 60 QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMV---ELSKLQEYKSELDE 116
Q ++++ + +QE E++E K L++E +NL + ++ + EL L+E +D+
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK 324
Query: 117 RAMQAVEKLKEIH 129
+ + +H
Sbjct: 325 LESEVSRYKERLH 337
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 48.9 bits (115), Expect = 2e-06
Identities = 35/140 (25%), Positives = 70/140 (50%), Gaps = 12/140 (8%)
Query: 12 EDFVCHEDLKTDQLKMDIL------IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE 65
E+ + HE +K K+ + IKK + + + E + ++ +L K+N+++Q++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 66 LLSMKKVQQECEKLEENQKMLEEEILNLKTHME---NSMVELSKLQEYKSELDERAMQA- 121
+ ++K ++ E LE+ LE E LK ++ N +L L++ S+LDE ++
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 122 --VEKLKEIHLQVTCLNQSN 139
VE LK +++ L N
Sbjct: 708 RNVESLKCASMKMAQLQLEN 727
Score = 38.1 bits (87), Expect = 0.003
Identities = 23/103 (22%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
E L+ +DI ++L++ ++ + + + S+ +L +NQ +Q+ L +K + E
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811
Query: 78 KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
+LE+ K LE+E L+ + E +L++ ++E+ + ++
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQ-QAEIKDTTLE 853
Score = 36.6 bits (83), Expect = 0.008
Identities = 34/133 (25%), Positives = 72/133 (54%), Gaps = 9/133 (6%)
Query: 20 LKTDQLKMDILIKKLKQKFD--DLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
L+ D+ +++ K+L+Q+ + D EE V K NL K+N+ + +E+ K+ +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNV--KIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 78 KLE-ENQKMLEEEILNLKTHM---ENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVT 133
+LE EN+++++ +++KT + E+ + E K Q+ ++L E+ +EK+ ++
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELEKIGLNKERLL 943
Query: 134 CLNQSNDSHYGVI 146
QS D Y ++
Sbjct: 944 HDEQSTDDRYKLL 956
Score = 34.7 bits (78), Expect = 0.029
Identities = 27/122 (22%), Positives = 61/122 (50%), Gaps = 6/122 (4%)
Query: 24 QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQ 83
Q+ + +K ++++ L + SSK + + + I++EL K+ + E+LE
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634
Query: 84 KMLEE--EILNLK-THMENSMVELSKLQEYKSELD---ERAMQAVEKLKEIHLQVTCLNQ 137
LE+ E+L K T+++ + ++ L++ SEL+ + + ++ K + Q+ L +
Sbjct: 635 HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEK 694
Query: 138 SN 139
N
Sbjct: 695 EN 696
Score = 33.5 bits (75), Expect = 0.066
Identities = 30/133 (22%), Positives = 68/133 (51%), Gaps = 19/133 (14%)
Query: 25 LKMDILIKKLKQKFDDLMAEEEAV---SSKCVNLSKDNQ-------VIQQELLSMKKVQQ 74
LK+++ + L + ++L ++V +SK + + K+NQ +++ E++ K+ Q
Sbjct: 463 LKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQ 522
Query: 75 ECEKLEEN----QKMLEEEILNLKTHMENSMVELSK----LQEYKSELDERAMQAVE-KL 125
C+ L ++ + LE+ I L+ + E + L + L + S L +R+ + E ++
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV 582
Query: 126 KEIHLQVTCLNQS 138
K+I + L++S
Sbjct: 583 KDIEKENKILHES 595
Score = 33.5 bits (75), Expect = 0.066
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 14/130 (10%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
E L+TD + L+ K + L AE SK + QQ ++ K+ +CE
Sbjct: 1261 EVLQTDHKNLKSLLNNSKLEQTRLEAE----------FSKLKEQYQQLDITSTKLNNQCE 1310
Query: 78 KLEENQKMLEEEILNLKTHMENSMVE----LSKLQEYKSELDERAMQAVEKLKEIHLQVT 133
L + + LEEE +L ++ M++ L + E K Q ++KL E+ Q
Sbjct: 1311 LLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKE 1370
Query: 134 CLNQSNDSHY 143
L + Y
Sbjct: 1371 KLEEKIMDQY 1380
Score = 31.6 bits (70), Expect = 0.25
Identities = 27/127 (21%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ--- 74
E L+ + ++D +L++ + L + S K L +N+ ++ E +KK +
Sbjct: 690 ESLEKENSQLDEENLELRRNVESL----KCASMKMAQLQLENKELESEKEQLKKGLELLK 745
Query: 75 ----ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHL 130
+ E+LE + + L+ E L+ +ENS ++ +L+ +L+ + L+E+ +
Sbjct: 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKI 805
Query: 131 QVTCLNQ 137
L Q
Sbjct: 806 SSKRLEQ 812
Score = 30.4 bits (67), Expect = 0.56
Identities = 27/108 (25%), Positives = 51/108 (47%), Gaps = 6/108 (5%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI 90
+KK F +L + E++ + L ++N +++ + S+K + +L+ K LE E
Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Query: 91 LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQS 138
LK + EL K K+E E + Q ++ ++ LQ T N +
Sbjct: 735 EQLKKGL-----ELLKASFKKTERLEVSYQGLD-IENQRLQKTLENSN 776
Score = 30.4 bits (67), Expect = 0.56
Identities = 20/113 (17%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM----LEE 88
K +++ + E V + + + ++N +Q E ++K ++ E N + L+
Sbjct: 1028 KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR 1087
Query: 89 EILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDS 141
+ ++L+ + +KLQ S L+ ++ + + ++ +Q + L N+S
Sbjct: 1088 QTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENES 1140
Score = 30.0 bits (66), Expect = 0.73
Identities = 19/83 (22%), Positives = 46/83 (55%), Gaps = 9/83 (10%)
Query: 11 NEDFVCHEDLKTD------QLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQ 64
N++ + H++ TD + K++ +KK + ++ +A EA + N NQ ++Q
Sbjct: 938 NKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNY---NQQLRQ 994
Query: 65 ELLSMKKVQQECEKLEENQKMLE 87
EL ++KK + ++ ++ ++M++
Sbjct: 995 ELKTVKKNYEALKQRQDEERMVQ 1017
Score = 28.9 bits (63), Expect = 1.6
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query: 26 KMDILIKKLKQKFDDLMAEE---EAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEEN 82
+++ L K LK + + ++ E E V+++ L +N + + K E E L+ +
Sbjct: 1210 QLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK---ETEVLQTD 1266
Query: 83 QKMLEEEILNLKTHMENSMVELSKLQEYKSELD 115
K L+ + N K E SKL+E +LD
Sbjct: 1267 HKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLD 1299
Score = 27.3 bits (59), Expect = 4.7
Identities = 20/94 (21%), Positives = 42/94 (44%), Gaps = 4/94 (4%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
K++ + + K++ D+ E ++ L +DNQV+ + ++ + +
Sbjct: 324 KLESEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379
Query: 86 LEEEILNLKTHMENSMVELSKLQEYKSELDERAM 119
LE+E L LK + + +E ++ EL E M
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Score = 26.6 bits (57), Expect = 8.0
Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 56 SKDNQVIQQELLSMK-KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSEL 114
++ Q + EL K K+++ ++LEE E++L+ K +E +EL +LQ+ L
Sbjct: 243 TESRQHLSVELADAKAKIRRLRQELEEKT----EQLLDCKQELEQMEIELKRLQQENMNL 298
Query: 115 DERAMQA 121
A A
Sbjct: 299 LSDARSA 305
Score = 26.6 bits (57), Expect = 8.0
Identities = 16/73 (21%), Positives = 37/73 (50%), Gaps = 3/73 (4%)
Query: 60 QVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMV---ELSKLQEYKSELDE 116
Q ++++ + +QE E++E K L++E +NL + ++ + EL L+E +D+
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK 324
Query: 117 RAMQAVEKLKEIH 129
+ + +H
Sbjct: 325 LESEVSRYKERLH 337
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 47.0 bits (110), Expect = 6e-06
Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 6/112 (5%)
Query: 35 KQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK-----KVQQECEKLEENQKMLEEE 89
+QK+ ++ E E ++ + VNLSK+ Q L ++K K Q+ EK E Q+ L E
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERL-NE 888
Query: 90 ILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDS 141
+ LK +EN L ++ K+ + E+ Q +E++K + + L Q +S
Sbjct: 889 MEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQES 940
Score = 36.2 bits (82), Expect = 0.010
Identities = 32/159 (20%), Positives = 73/159 (45%), Gaps = 29/159 (18%)
Query: 2 TINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQV 61
TIN L V +E ++ T Q +++ + KL+ K ++ +EE + K ++
Sbjct: 1492 TINELRVNLSEK---ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQIS------E 1542
Query: 62 IQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELS--------------KL 107
+Q+++ +K+ ++ + + + +E ++L L ++ S E+ L
Sbjct: 1543 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL 1602
Query: 108 QEYKSELDERAMQAVEKLKEIH------LQVTCLNQSND 140
Q + +L E + V K+KE L++T +N++ +
Sbjct: 1603 QIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQE 1641
Score = 33.5 bits (75), Expect = 0.066
Identities = 27/107 (25%), Positives = 57/107 (53%), Gaps = 6/107 (5%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMK--KVQQE 75
E LKTD LK +I + Q+ L+ +E + V K++ + ++ LS ++ +
Sbjct: 1067 EQLKTD-LKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEV 1125
Query: 76 CEKLEENQKMLEE---EILNLKTHMENSMVELSKLQEYKSELDERAM 119
EKL+E + L+E ++LN++ M ++++++ K+EL + +
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKEL 1172
Score = 33.1 bits (74), Expect = 0.086
Identities = 23/99 (23%), Positives = 49/99 (49%), Gaps = 6/99 (6%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
KL++K +L A E + + L KD Q+++ M++++++ + LE E LN
Sbjct: 1817 KLQEKIQELKANEHQL----ITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLN 1872
Query: 93 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQ 131
L + ++ E+ + + + L R ++ KL+ L+
Sbjct: 1873 LAQKLHENLEEMKSVMKERDNL--RRVEETLKLERDQLK 1909
Score = 32.7 bits (73), Expect = 0.11
Identities = 25/116 (21%), Positives = 55/116 (47%), Gaps = 17/116 (14%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI 90
I+ LK++F+ E + ++ + L+ Q++ + L M+ V +E + L ++ L+
Sbjct: 1646 IEHLKEQFETQKLNLENIETENIRLT---QILHENLEEMRSVTKERDDLRSVEETLK--- 1699
Query: 91 LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSNDSHYGVI 146
VE +L+E E R ++ E+LK +H+ + ++ D G++
Sbjct: 1700 -----------VERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIV 1744
Score = 32.7 bits (73), Expect = 0.11
Identities = 28/119 (23%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 15 VCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQEL----LSMK 70
+ H LK Q +D L + +K +++ ++ + L + IQ+EL + +K
Sbjct: 1725 IVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLK 1784
Query: 71 KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIH 129
+ Q+ +KL +++ N++ +ENS +KLQE EL Q + K+++
Sbjct: 1785 EQQETIDKLRGIVSEKTDKLSNMQKDLENSN---AKLQEKIQELKANEHQLITLKKDVN 1840
Score = 30.0 bits (66), Expect = 0.73
Identities = 28/86 (32%), Positives = 41/86 (47%), Gaps = 8/86 (9%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQV---IQQELLSMKKVQQECEKLEENQKMLEEE 89
+L + D L EE + K L + Q +Q+E+ M+K E E L+ K E
Sbjct: 1114 ELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE-- 1171
Query: 90 ILNLKTHMENSMVELS-KLQEYKSEL 114
L L+ HME +EL+ KL E E+
Sbjct: 1172 -LTLE-HMETERLELAQKLNENYEEV 1195
Score = 28.9 bits (63), Expect = 1.6
Identities = 28/113 (24%), Positives = 56/113 (49%), Gaps = 7/113 (6%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
+D+ Q K+ + ++LK++ D + + +NL+ Q + + L MK V +E +
Sbjct: 1837 KDVNETQKKVSEM-EQLKKQIKDQSLTLSKLEIENLNLA---QKLHENLEEMKSVMKERD 1892
Query: 78 KLEENQKMLEEEILNLKTHMENSMV-ELSKLQEYKSE--LDERAMQAVEKLKE 127
L ++ L+ E LK ++ + +L QE K+ L + + V+KL+E
Sbjct: 1893 NLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLRE 1945
Score = 28.1 bits (61), Expect = 2.8
Identities = 20/100 (20%), Positives = 48/100 (48%), Gaps = 10/100 (10%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
+L+Q + ++AE+E + + +++ + + Q+E L + K +E +
Sbjct: 1054 ELQQMLESVIAEKEQLKTD----------LKENIEMTIENQEELRLLGDELKKQQEIVAQ 1103
Query: 93 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
K H ELS+ + +E++E+ + ++L+E Q+
Sbjct: 1104 EKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQL 1143
Score = 26.6 bits (57), Expect = 8.0
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 18/74 (24%)
Query: 57 KDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDE 116
KDN++I+Q+ +K+ ++ E Q+MLE I ++ ++ K++L E
Sbjct: 1034 KDNEIIEQQ----RKIFSLIQEKNELQQMLESVI--------------AEKEQLKTDLKE 1075
Query: 117 RAMQAVEKLKEIHL 130
+E +E+ L
Sbjct: 1076 NIEMTIENQEELRL 1089
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 45.4 bits (106), Expect = 2e-05
Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 4/112 (3%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
KKL Q+ D EAV++KC +L K Q +Q E ++ +++ C L++ Q+ +
Sbjct: 1395 KKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454
Query: 88 EEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSN 139
+ + K E + EL Q+ L + +E Q+ L + N
Sbjct: 1455 KILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKREN 1506
Score = 37.0 bits (84), Expect = 0.006
Identities = 29/123 (23%), Positives = 61/123 (49%), Gaps = 13/123 (10%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ 74
+DL+ ++ K++ L K KL+Q+ DDL E ++L + + ++ +L K Q+
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL---KLAQE 1068
Query: 75 ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTC 134
+E +++ L+E++ + E+S LQ + MQ +K+KE+ ++
Sbjct: 1069 STMDIENDKQQLDEKL-------KKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEE 1121
Query: 135 LNQ 137
L +
Sbjct: 1122 LEE 1124
Score = 36.6 bits (83), Expect = 0.008
Identities = 31/130 (23%), Positives = 63/130 (48%), Gaps = 18/130 (13%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
C + +KT +++++ IK++ ++ +D L A++ + +C L KD ++ L+
Sbjct: 909 CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 964
Query: 69 MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEI 128
+ KV++E E K L EE+ L ++KL + K L E Q ++ L+
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDE-------TIAKLTKEKKALQEAHQQTLDDLQAE 1017
Query: 129 HLQVTCLNQS 138
+V L ++
Sbjct: 1018 EDKVNTLTKA 1027
Score = 33.9 bits (76), Expect = 0.050
Identities = 14/46 (30%), Positives = 29/46 (63%)
Query: 87 EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
E+E+ N+K E + EL+K + + EL+E+ + +++ ++ LQV
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895
Score = 29.6 bits (65), Expect = 0.95
Identities = 24/113 (21%), Positives = 52/113 (46%), Gaps = 15/113 (13%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
K++ I +++ + +D++ E K D ++ +EL KK Q LE +K
Sbjct: 1733 KLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1789
Query: 86 LEEEILNLKTHMENS--------MVELSKLQ----EYKSELDERAMQAVEKLK 126
LE+ + +L+ ++ + ++ KL+ E + E++ + VE +K
Sbjct: 1790 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVK 1842
Score = 28.9 bits (63), Expect = 1.6
Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 11/77 (14%)
Query: 63 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
++E+ +MK K ++E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERC 909
Query: 119 MQAVE-------KLKEI 128
Q ++ K+KE+
Sbjct: 910 DQLIKTKIQLEAKIKEV 926
Score = 28.1 bits (61), Expect = 2.8
Identities = 28/134 (20%), Positives = 58/134 (43%), Gaps = 14/134 (10%)
Query: 19 DLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKK------- 71
DL+ L+ + L++K D +AE + + NL + Q +++E MK
Sbjct: 1181 DLEEATLQHEATAATLRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEMKMEIDDLAS 1237
Query: 72 ----VQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKE 127
V + LE+ + LE+++ +KT E ++ L ++ L + + +L E
Sbjct: 1238 NMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE 1297
Query: 128 IHLQVTCLNQSNDS 141
V+ L++ +
Sbjct: 1298 KDTLVSQLSRGKQA 1311
Score = 28.1 bits (61), Expect = 2.8
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
Query: 34 LKQKFDDLMAEEEAVSSKCVNLSKDN-QVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
L++++++ E+EA + +SK N +V Q Q E+LEE +K L + + +
Sbjct: 1347 LREQYEE---EQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403
Query: 93 LKTHMENSMVELSKLQEYKSEL 114
+ H+E + + L++ K L
Sbjct: 1404 AEEHVEAVNAKCASLEKTKQRL 1425
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 45.4 bits (106), Expect = 2e-05
Identities = 25/96 (26%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI 90
+++++Q +L E + + C++L K N +Q EL +K Q+E E L+ K LE ++
Sbjct: 142 VEEIEQHNKELCKENQELKDSCISLQKQNSDMQAEL---QKKQEELETLQSINKKLELKV 198
Query: 91 LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLK 126
K + E +++L + + S +E+ V++L+
Sbjct: 199 KEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQLQ 234
Score = 30.8 bits (68), Expect = 0.43
Identities = 21/87 (24%), Positives = 46/87 (52%), Gaps = 9/87 (10%)
Query: 14 FVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSK---DNQVIQQELLSMK 70
F+ + + DQ K++ ++++KQ M +++ + + +LSK +N++I L
Sbjct: 269 FLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNAL---- 324
Query: 71 KVQQECEKLEENQKMLEEEILNLKTHM 97
Q++ E+LE +L+ E L ++M
Sbjct: 325 --QRQKERLEGENDLLKRENSRLLSYM 349
Score = 28.9 bits (63), Expect = 1.6
Identities = 26/125 (20%), Positives = 51/125 (40%), Gaps = 4/125 (3%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC--- 76
LK KM +K+ + D L A+ + L + +Q ++L +KK
Sbjct: 212 LKEQNQKMSSENEKMGIRVDQLQAQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLS 271
Query: 77 -EKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCL 135
+ ++QK LE+ + +K + +M + +L + +L +R + + Q L
Sbjct: 272 LTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIICNALQRQKERL 331
Query: 136 NQSND 140
ND
Sbjct: 332 EGEND 336
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 44.7 bits (104), Expect = 3e-05
Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 4/112 (3%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
KKL Q+ + EAV++KC +L K Q +Q E +L +++ C L++ Q+ +
Sbjct: 1394 KKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFD 1453
Query: 88 EEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSN 139
+ + K E + EL Q+ L + +E Q+ L + N
Sbjct: 1454 KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRREN 1505
Score = 35.4 bits (80), Expect = 0.017
Identities = 29/128 (22%), Positives = 61/128 (47%), Gaps = 17/128 (13%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLSMK 70
E L ++++++ IK++ ++ ++ L A++ + +C L KD ++ L++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLA 965
Query: 71 KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHL 130
KV++E E K L EE+ L ++KL + K L E Q ++ L+
Sbjct: 966 KVEKEKHATENKVKNLTEEMAGLDE-------TIAKLSKEKKALQETHQQTLDDLQAEED 1018
Query: 131 QVTCLNQS 138
+V L ++
Sbjct: 1019 KVNILTKA 1026
Score = 34.7 bits (78), Expect = 0.029
Identities = 30/134 (22%), Positives = 60/134 (44%), Gaps = 14/134 (10%)
Query: 19 DLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEK 78
DL+ L+ + ++ L++K D MAE + + NL + Q +++E +K +
Sbjct: 1180 DLEEATLQHEAMVAALRKKHADSMAE---LGEQIDNLQRVKQKLEKEKSELKMETDDLSS 1236
Query: 79 -----------LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKE 127
LE+ + LE+++ LKT E ++ L ++ L A + +L E
Sbjct: 1237 NAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDE 1296
Query: 128 IHLQVTCLNQSNDS 141
V+ L++S +
Sbjct: 1297 KDALVSQLSRSKQA 1310
Score = 33.9 bits (76), Expect = 0.050
Identities = 24/115 (20%), Positives = 57/115 (49%), Gaps = 3/115 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECE 77
++L+ + K++ +LK + DDL + EA+S NL K + ++ ++ +K ++E +
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270
Query: 78 KLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
+L + L + L+T +L + S+L + ++++E+ Q+
Sbjct: 1271 RLIND---LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQL 1322
Score = 32.3 bits (72), Expect = 0.15
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 14/117 (11%)
Query: 35 KQKFDDLMAEEEAV---SSKCVNLSKDNQVIQQELLSMKKVQQECE----KLEENQKMLE 87
+Q DDL AEE+ V + L + ++ L KK++ + E KLE + K+ +
Sbjct: 1007 QQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1066
Query: 88 EEILNLKTHMENSMVELSKLQEYKSEL-----DERA--MQAVEKLKEIHLQVTCLNQ 137
E ++++ + +L K + S L DE+A +Q +K+KE+ ++ L +
Sbjct: 1067 ESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGE 1123
Score = 29.3 bits (64), Expect = 1.2
Identities = 12/46 (26%), Positives = 28/46 (60%)
Query: 87 EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
E+E+ +K + + EL+K + + EL+E+ + +++ ++ LQV
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQV 894
Score = 28.1 bits (61), Expect = 2.8
Identities = 18/77 (23%), Positives = 39/77 (50%), Gaps = 11/77 (14%)
Query: 63 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
++E+ +MK K + E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 119 MQAVE-------KLKEI 128
Q ++ K+KE+
Sbjct: 909 EQLIKNKIQLEAKIKEV 925
Score = 27.3 bits (59), Expect = 4.7
Identities = 16/75 (21%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
K++ + +L+ + ++++ E K D ++ +EL KK Q LE +K
Sbjct: 1732 KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1788
Query: 86 LEEEILNLKTHMENS 100
LE+ + +L+ ++ +
Sbjct: 1789 LEQTVKDLQHRLDEA 1803
Score = 26.9 bits (58), Expect = 6.2
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 34 LKQKFDDLMAEEEAVSSKCVNLSKDN-QVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
L++++++ E+E + LSK N +V Q Q E+LEE +K L + +
Sbjct: 1346 LREQYEE---EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQE 1402
Query: 93 LKTHMENSMVELSKLQEYKSEL 114
+ H+E + + L++ K L
Sbjct: 1403 AEEHVEAVNAKCASLEKTKQRL 1424
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 44.7 bits (104), Expect = 3e-05
Identities = 28/112 (25%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
KKL Q+ D EAV+SKC +L K Q +Q E ++ +++ C L++ Q+ +
Sbjct: 1395 KKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD 1454
Query: 88 EEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSN 139
+ + K E + EL Q+ L + +E + L + N
Sbjct: 1455 KVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKREN 1506
Score = 41.6 bits (96), Expect = 2e-04
Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELL----SMK 70
+DL+ ++ K++ L K KL+Q+ DDL E C++L + + ++ +L S
Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTM 1071
Query: 71 KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLK 126
+ + ++L E K E E+ NL+ +E+ +LQ+ EL R + E+++
Sbjct: 1072 DTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIE 1127
Score = 40.4 bits (93), Expect = 5e-04
Identities = 28/112 (25%), Positives = 52/112 (46%), Gaps = 11/112 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC--- 76
L Q D ++ + KQK+++ AE EA K+++ + EL +K +E
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQ-------KESRSLSTELFKVKNAYEESLDH 1498
Query: 77 -EKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKE 127
E L+ K L++EI +L + + +L++ K +LD + L+E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEE 1550
Score = 38.1 bits (87), Expect = 0.003
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 13/137 (9%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
C + +KT +++++ IK++ ++ +D L A++ + +C L KD ++ L+
Sbjct: 909 CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 964
Query: 69 MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELDERAMQAVEKLKE 127
+ KV++E E K L EE+ L + E LQE ++ LD+ M+ +K+
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEE-DKVNT 1023
Query: 128 IHLQVTCLNQSNDSHYG 144
+ T L Q D G
Sbjct: 1024 LTKAKTKLEQQVDDLEG 1040
Score = 33.9 bits (76), Expect = 0.050
Identities = 14/46 (30%), Positives = 29/46 (63%)
Query: 87 EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
E+E+ N+K E + EL+K + + EL+E+ + +++ ++ LQV
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895
Score = 32.3 bits (72), Expect = 0.15
Identities = 26/117 (22%), Positives = 52/117 (44%), Gaps = 14/117 (11%)
Query: 35 KQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEI---- 90
+Q DDL EE+ V++ +K Q + S+++ ++ C LE ++ LE ++
Sbjct: 1008 QQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067
Query: 91 ----------LNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQ 137
L ++ E+S LQ + A+Q +K+KE+ ++ L +
Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEE 1124
Score = 30.4 bits (67), Expect = 0.56
Identities = 30/131 (22%), Positives = 61/131 (46%), Gaps = 8/131 (6%)
Query: 19 DLKTDQLKMDILIKKLKQKFDDLMAE--EEAVSSKCVN--LSKDNQVIQQELLSMKKVQQ 74
DL+ L+ + L++K D +AE E+ S + V L K+ ++ E+ + +
Sbjct: 1181 DLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNME 1240
Query: 75 ECEKLEEN-QKM---LEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHL 130
K + N +KM LE+++ +KT E +++L K+ L + + +L E
Sbjct: 1241 TVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDA 1300
Query: 131 QVTCLNQSNDS 141
V+ L++ +
Sbjct: 1301 MVSQLSRGKQA 1311
Score = 30.0 bits (66), Expect = 0.73
Identities = 21/112 (18%), Positives = 54/112 (48%), Gaps = 17/112 (15%)
Query: 30 LIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKMLEEE 89
++K + DD + ++ + + + + ++Q E+ ++++ E+ E +KM E+E
Sbjct: 1653 ILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEV---EELRASLERTERGRKMAEQE 1709
Query: 90 ILNLK-----THMENSMV---------ELSKLQEYKSELDERAMQAVEKLKE 127
+L+ H +N+ + ++S++Q ++ + A A EK K+
Sbjct: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKK 1761
Score = 28.9 bits (63), Expect = 1.6
Identities = 18/77 (23%), Positives = 40/77 (51%), Gaps = 11/77 (14%)
Query: 63 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
++E+ +MK K ++E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909
Query: 119 MQAVE-------KLKEI 128
Q ++ K+KE+
Sbjct: 910 DQLIKTKIQLEAKIKEV 926
Score = 28.1 bits (61), Expect = 2.8
Identities = 21/82 (25%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
Query: 34 LKQKFDDLMAEEEAVSSKCVNLSKDN-QVIQQELLSMKKVQQECEKLEENQKMLEEEILN 92
L++++++ E+EA + +SK N +V Q Q E+LEE +K L + + +
Sbjct: 1347 LREQYEE---EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQD 1403
Query: 93 LKTHMENSMVELSKLQEYKSEL 114
+ H+E + + L++ K L
Sbjct: 1404 AEEHVEAVNSKCASLEKTKQRL 1425
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 43.9 bits (102), Expect = 5e-05
Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
KKL Q+ + E +SKC +L K Q +Q E + +++ C L++ Q+ +
Sbjct: 1395 KKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFD 1454
Query: 88 EEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQSN 139
+ + K ++ S EL Q+ L + +E+ Q+ L + N
Sbjct: 1455 KVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506
Score = 39.7 bits (91), Expect = 0.001
Identities = 31/129 (24%), Positives = 66/129 (51%), Gaps = 13/129 (10%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQ 74
+DL+ ++ K++ LIK KL+Q+ DDL E +L + + ++ +L K Q+
Sbjct: 1012 DDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL---KMSQE 1068
Query: 75 ECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTC 134
LE +++ +EE++ + ELS+LQ + ++Q +K+KE+ ++
Sbjct: 1069 SIMDLENDKQQIEEKL-------KKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEE 1121
Query: 135 LNQSNDSHY 143
L + ++ +
Sbjct: 1122 LEEEIEAEH 1130
Score = 37.7 bits (86), Expect = 0.003
Identities = 28/116 (24%), Positives = 58/116 (50%), Gaps = 17/116 (14%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLSMK 70
E L ++ ++ +K+L ++ ++ L+A++ + KC +L +D ++ L++
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE---LTLT 966
Query: 71 KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLK 126
KV++E E K L EE+ L+ + +SKL + K L E Q ++ L+
Sbjct: 967 KVEKEKHATENKVKNLSEEMTALEEN-------ISKLTKEKKSLQEAHQQTLDDLQ 1015
Score = 35.0 bits (79), Expect = 0.023
Identities = 22/104 (21%), Positives = 57/104 (54%), Gaps = 8/104 (7%)
Query: 33 KLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEK----LEENQKMLE- 87
K++ +++++ + E + + NL ++ + +++ K QE EK +E+ + L+
Sbjct: 1487 KMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQV 1546
Query: 88 --EEILNLKTHMENSMVELS-KLQEYKSELDERAMQAVEKLKEI 128
EE+ H E+ ++ + +L + KSELD + ++ E+++++
Sbjct: 1547 ALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQL 1590
Score = 34.3 bits (77), Expect = 0.039
Identities = 34/145 (23%), Positives = 71/145 (48%), Gaps = 28/145 (19%)
Query: 12 EDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEE----AVSSKCVNLSKDNQ----VIQ 63
EDF E K + + + K+L++K L+ E+ V S+ NL + +I+
Sbjct: 858 EDF---ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIK 914
Query: 64 QELLSMKKVQQECEKLEENQKM----------LEEEILNLKTHMENSMVELSKLQEYKSE 113
++L KV++ E+LEE ++M LE++ +LK +++ + L+K+++ K
Sbjct: 915 SKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHA 974
Query: 114 LDERAMQAVEKLKEIHLQVTCLNQS 138
+ K+K + ++T L ++
Sbjct: 975 TEN-------KVKNLSEEMTALEEN 992
Score = 33.5 bits (75), Expect = 0.066
Identities = 26/108 (24%), Positives = 54/108 (50%), Gaps = 5/108 (4%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLS----KDNQVIQQELLSMKKVQQE 75
L Q D ++ + KQK D+ AE EA + +LS K ++ + ++ +++E
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRE 1505
Query: 76 CEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVE 123
+ L+E L E+I +++ + +++ KS+L + A++ VE
Sbjct: 1506 NKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDL-QVALEEVE 1552
Score = 33.1 bits (74), Expect = 0.086
Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 11/107 (10%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKV----QQECEKLEENQKMLE 87
++L+ + +DLM + E + C L K + + L K+ Q E E ++ + L
Sbjct: 1423 QRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLS 1482
Query: 88 EEILNLKTHMENSMVELS-------KLQEYKSELDERAMQAVEKLKE 127
E+ ++ E + +L LQE S+L E+ + + L+E
Sbjct: 1483 TELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQE 1529
Score = 30.0 bits (66), Expect = 0.73
Identities = 12/46 (26%), Positives = 28/46 (60%)
Query: 87 EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
E+E+ +K E + EL++ + + EL+E+ + +++ ++ LQV
Sbjct: 850 EKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQV 895
Score = 29.6 bits (65), Expect = 0.95
Identities = 27/123 (21%), Positives = 48/123 (39%), Gaps = 26/123 (21%)
Query: 31 IKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEK------------ 78
+K + DD + E + + + + N ++ +EL MK ++ E+
Sbjct: 1654 LKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDA 1713
Query: 79 -------------LEENQKMLEEEILNLKTHMENSMVELSKLQE-YKSELDERAMQAVEK 124
L +K LE +I + +ENS+ E +E K + + AM A E
Sbjct: 1714 SDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEEL 1773
Query: 125 LKE 127
KE
Sbjct: 1774 KKE 1776
Score = 29.6 bits (65), Expect = 0.95
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 15/116 (12%)
Query: 26 KMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEKLEENQKM 85
K++ I + + + ++ + E K D ++ +EL KK Q LE +K
Sbjct: 1733 KLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1789
Query: 86 LEEEILNLKTHMENS--------MVELSKLQ----EYKSELDERAMQAVEKLKEIH 129
LE+ + +L+ ++ + ++ KL+ E ++ELD + E LK H
Sbjct: 1790 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAH 1845
Score = 28.5 bits (62), Expect = 2.1
Identities = 25/117 (21%), Positives = 51/117 (43%), Gaps = 15/117 (12%)
Query: 19 DLKTDQLKMDILIKK-------LKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKK 71
DL+ D+ +++ +KK L+ K DD K L + +++E+ +
Sbjct: 1072 DLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHT 1131
Query: 72 VQQECEK--------LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
++ + EK LEE + LEE +E + ++ Q+ + +L+E +Q
Sbjct: 1132 LRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188
>gi|156546890 WW and C2 domain containing 2 [Homo sapiens]
Length = 1192
Score = 43.5 bits (101), Expect = 6e-05
Identities = 28/122 (22%), Positives = 58/122 (47%)
Query: 17 HEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQEC 76
+E+ K + I + KL + + E +N ++ Q + K+ Q E
Sbjct: 312 YEEAKRSMANLKIELSKLDSEAWPGALDIEKEKLMLINEKEELLKELQFVTPQKRTQDEL 371
Query: 77 EKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLN 136
E+LE ++ LEEE+L+++ ++ E +L+E + EL ++ + + +H Q+ L+
Sbjct: 372 ERLEAERQRLEEELLSVRGTPSRALAERLRLEERRKELLQKLEETTKLTTYLHSQLKSLS 431
Query: 137 QS 138
S
Sbjct: 432 AS 433
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 42.7 bits (99), Expect = 1e-04
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 5/86 (5%)
Query: 32 KKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQE----LLSMKKVQQECEKLEENQKMLE 87
KKL Q+ D + EAV++KC +L K Q +Q E ++ +++ L++ Q+ +
Sbjct: 1392 KKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451
Query: 88 EEILNLKTHMENSMVEL-SKLQEYKS 112
+ + KT E S EL + L+E +S
Sbjct: 1452 KVLAEWKTKCEESQAELEASLKESRS 1477
Score = 37.7 bits (86), Expect = 0.003
Identities = 33/117 (28%), Positives = 58/117 (49%), Gaps = 14/117 (11%)
Query: 35 KQKFDDLMAEEEAVSSKCVNLSK-DNQV--IQQELLSMKKVQQECE----KLEENQKMLE 87
+Q DDL AEE+ V+S SK + QV ++ L KK++ + E KLE + K+ +
Sbjct: 1005 QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 1064
Query: 88 EEILNLKT-------HMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQVTCLNQ 137
E IL+L+ ++ E +LQ + +Q +K+KE+ ++ L +
Sbjct: 1065 ESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEE 1121
Score = 37.4 bits (85), Expect = 0.005
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 18/130 (13%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDD-------LMAEEEAVSSKCVNLSKDNQVIQQELLS 68
C + +K + +++ IK++ ++ +D L A++ + +C L KD ++ L+
Sbjct: 906 CDQLIKA-KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 961
Query: 69 MKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEI 128
+ KV++E E K L EE+ L ++KL K L E QA++ L+
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDE-------TIAKLTREKKALQEAHQQALDDLQAE 1014
Query: 129 HLQVTCLNQS 138
+V LN++
Sbjct: 1015 EDKVNSLNKT 1024
Score = 30.8 bits (68), Expect = 0.43
Identities = 13/46 (28%), Positives = 28/46 (60%)
Query: 87 EEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEIHLQV 132
E+E+ +K + + EL+K + + EL+E+ + V++ ++ LQV
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQV 892
Score = 28.1 bits (61), Expect = 2.8
Identities = 19/77 (24%), Positives = 38/77 (49%), Gaps = 11/77 (14%)
Query: 63 QQELLSMK----KVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERA 118
++E+ +MK K + E K E +K LEE+++ L + +++ E + +ER
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
Query: 119 MQAVE-------KLKEI 128
Q ++ K+KE+
Sbjct: 907 DQLIKAKFQLEAKIKEV 923
Score = 28.1 bits (61), Expect = 2.8
Identities = 24/110 (21%), Positives = 55/110 (50%), Gaps = 20/110 (18%)
Query: 19 DLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQVIQQELLSMKKVQQECEK 78
DL+ L+ + ++ L++K D +AE + +++ ++++V+Q+ EK
Sbjct: 1178 DLEEATLQHEAMVAALRKKHADSVAE-----------------LGEQIDNLQRVKQKLEK 1220
Query: 79 LEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQAVEKLKEI 128
+ K+ EI +L + ME+ + L++ L+++ +A K +EI
Sbjct: 1221 EKSEFKL---EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.336
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,758,933
Number of Sequences: 37866
Number of extensions: 194152
Number of successful extensions: 4099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 348
Number of HSP's successfully gapped in prelim test: 494
Number of HSP's that attempted gapping in prelim test: 1831
Number of HSP's gapped (non-prelim): 2396
length of query: 146
length of database: 18,247,518
effective HSP length: 92
effective length of query: 54
effective length of database: 14,763,846
effective search space: 797247684
effective search space used: 797247684
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.