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Search of human proteins with 239745448
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 846 0.0
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 844 0.0
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 844 0.0
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 347 1e-95
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 145 5e-35
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 145 5e-35
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 119 7e-27
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 112 5e-25
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 112 6e-25
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 60 4e-09
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 60 4e-09
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 48 1e-05
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 47 2e-05
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 47 2e-05
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 47 2e-05
gi|10190720 NmrA-like family domain containing 1 [Homo sapiens] 36 0.058
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] 36 0.058
gi|31543615 dehydrogenase/reductase (SDR family) member 3 [Homo ... 32 1.1
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun... 31 1.9
gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 30 4.1
gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 30 4.1
gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9... 30 4.1
gi|4885371 H1 histone family, member 0 [Homo sapiens] 30 4.1
gi|123701326 zinc finger protein 831 [Homo sapiens] 30 4.1
gi|24797151 dimethylglycine dehydrogenase precursor [Homo sapiens] 29 7.0
gi|27436951 lamin B2 [Homo sapiens] 29 9.2
gi|148664218 POU transcription factor [Homo sapiens] 29 9.2
>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
Length = 422
Score = 846 bits (2186), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV 60
MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV
Sbjct: 1 MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV 60
Query: 61 ILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIES 120
ILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIES
Sbjct: 61 ILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIES 120
Query: 121 INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK 180
INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK
Sbjct: 121 INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK 180
Query: 181 AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK 240
AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK
Sbjct: 181 AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK 240
Query: 241 ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ 300
ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ
Sbjct: 241 ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ 300
Query: 301 PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA 360
PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA
Sbjct: 301 PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA 360
Query: 361 PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE 420
PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE
Sbjct: 361 PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE 420
Query: 421 RL 422
RL
Sbjct: 421 RL 422
>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
protein ENSP00000330812 [Homo sapiens]
Length = 422
Score = 844 bits (2181), Expect = 0.0
Identities = 421/422 (99%), Positives = 421/422 (99%)
Query: 1 MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV 60
MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV
Sbjct: 1 MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV 60
Query: 61 ILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIES 120
ILLDRRRPQWELSPETKFIQADVRDEEALY AFEGVDCVFHVASYGMSGAEKLQKEQIES
Sbjct: 61 ILLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIES 120
Query: 121 INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK 180
INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK
Sbjct: 121 INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK 180
Query: 181 AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK 240
AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK
Sbjct: 181 AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK 240
Query: 241 ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ 300
ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ
Sbjct: 241 ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ 300
Query: 301 PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA 360
PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA
Sbjct: 301 PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA 360
Query: 361 PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE 420
PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE
Sbjct: 361 PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE 420
Query: 421 RL 422
RL
Sbjct: 421 RL 422
>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
sapiens]
Length = 422
Score = 844 bits (2181), Expect = 0.0
Identities = 421/422 (99%), Positives = 421/422 (99%)
Query: 1 MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV 60
MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV
Sbjct: 1 MKSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSV 60
Query: 61 ILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIES 120
ILLDRRRPQWELSPETKFIQADVRDEEALY AFEGVDCVFHVASYGMSGAEKLQKEQIES
Sbjct: 61 ILLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIES 120
Query: 121 INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK 180
INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK
Sbjct: 121 INVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTK 180
Query: 181 AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK 240
AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK
Sbjct: 181 AIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHK 240
Query: 241 ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ 300
ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ
Sbjct: 241 ARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQ 300
Query: 301 PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA 360
PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA
Sbjct: 301 PWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYA 360
Query: 361 PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE 420
PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE
Sbjct: 361 PDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVE 420
Query: 421 RL 422
RL
Sbjct: 421 RL 422
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 347 bits (890), Expect = 1e-95
Identities = 181/360 (50%), Positives = 234/360 (65%), Gaps = 4/360 (1%)
Query: 28 PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87
P ++ ++ VL+TGG GY GF LG L ++G VIL D P + KFIQ D+R
Sbjct: 3 PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62
Query: 88 ALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145
+ +AF+ D CVFH+ASYGMSG E+L + I+ +NV GT ++ VC RRRVPRL+YTS
Sbjct: 63 DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122
Query: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204
T NV FGG+ I GDE S+PY PL H DHYSRTK+IA+Q L AN PL G G LRTC
Sbjct: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181
Query: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264
LRP GIYGP EQRHLPR+ +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL
Sbjct: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241
Query: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324
KG++ASGQ Y+I+DG VN FE+ PL E LGY+ P ++P + VY A + E +H L
Sbjct: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301
Query: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384
+ + P LTR+EV VTH F + KA+ +LGY F +AVE + R GS
Sbjct: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 145 bits (367), Expect = 5e-35
Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)
Query: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61
S P R + P+ K + ++ V GG G+LG + L G +V
Sbjct: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
Query: 62 LLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121
+ D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E +
Sbjct: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
Query: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181
N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK
Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
Query: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241
+ ++ L AN P L T + RP GI+GP + + +P + + F G+ K
Sbjct: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
Query: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301
+++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P
Sbjct: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
Query: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
+P Y A ++ L + + P+ L P T V H + +A+ +GY P
Sbjct: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
Query: 362 DKFRFADAVELYVQS 376
DA+E VQS
Sbjct: 352 -LVTMDDAMERTVQS 365
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 145 bits (367), Expect = 5e-35
Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)
Query: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61
S P R + P+ K + ++ V GG G+LG + L G +V
Sbjct: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
Query: 62 LLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121
+ D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E +
Sbjct: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
Query: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181
N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK
Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
Query: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241
+ ++ L AN P L T + RP GI+GP + + +P + + F G+ K
Sbjct: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
Query: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301
+++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P
Sbjct: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
Query: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
+P Y A ++ L + + P+ L P T V H + +A+ +GY P
Sbjct: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
Query: 362 DKFRFADAVELYVQS 376
DA+E VQS
Sbjct: 352 -LVTMDDAMERTVQS 365
>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 373
Score = 119 bits (297), Expect = 7e-27
Identities = 109/347 (31%), Positives = 159/347 (45%), Gaps = 33/347 (9%)
Query: 37 LVTGGGGYLGFSLGSHLAKSGT--SVILLDR------RRPQWELSPETKF--IQADVRDE 86
LVTG GG+LG + L K + +LD+ R +L +TK ++ D+ DE
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDE 66
Query: 87 EALYRAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142
L RA + V + H A +G++ +E I ++NV GT+L+++ CV+ VP I
Sbjct: 67 PFLKRACQDVSVIIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 121
Query: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDEHVDH-YSRTKAIADQLTLMANGMPLPGG 198
YTS++ VA + I+ G E+ PL+ Y +K +A++ L ANG L G
Sbjct: 122 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPAPYPHSKKLAEKAVLAANGWNLKNG 177
Query: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258
GTL TC LRP IYG E R L + + +N V+V N+ AH+LA
Sbjct: 178 GTLYTCALRPMYIYG-EGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILA 236
Query: 259 AEALTTAKGYVA-SGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314
AL K + GQ YYI+D ++ + K L W P S +Y
Sbjct: 237 LRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRW-SFPLSLMYWIG 295
Query: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
++E + LRPI + P R V TF KA+ L Y P
Sbjct: 296 FLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKP 342
>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
Length = 372
Score = 112 bits (281), Expect = 5e-25
Identities = 107/347 (30%), Positives = 157/347 (45%), Gaps = 33/347 (9%)
Query: 37 LVTGGGGYLGFSLGSHLA--KSGTSVILLDRR-RPQW-----ELSPETKF--IQADVRDE 86
LVTG GG LG + L K + LD+ RP+ +L TK ++ D+ DE
Sbjct: 6 LVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDE 65
Query: 87 EALYRAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142
L RA + V V H A +G++ +E I ++NV GT+L+++ CV+ VP I
Sbjct: 66 PFLKRACQDVSVVIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 120
Query: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDE-HVDHYSRTKAIADQLTLMANGMPLPGG 198
YTS++ VA + I+ G E+ PL+ Y +K +A++ L ANG L G
Sbjct: 121 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPTPYPYSKKLAEKAVLAANGWNLKNG 176
Query: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258
TL TC LRP IYG + + + G + +N V+V N+ AH+LA
Sbjct: 177 DTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKF-STVNPVYVGNVAWAHILA 235
Query: 259 AEAL-TTAKGYVASGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314
AL K GQ YYI+D ++ + + K L W +P + +Y
Sbjct: 236 LRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRW-SLPLTLMYWIG 294
Query: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361
++E + L PI S P R V TF KA+ L Y P
Sbjct: 295 FLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKP 341
>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform a [Homo sapiens]
Length = 369
Score = 112 bits (280), Expect = 6e-25
Identities = 112/373 (30%), Positives = 165/373 (44%), Gaps = 29/373 (7%)
Query: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGT---SVILLDRRRPQWELSPET-----K 77
A +A + LVTGG G+LG + L + + + D+ W +T
Sbjct: 2 ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVT 61
Query: 78 FIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRR 137
IQ DV + A G V H A + + + I +NV GT+ VI+ CV+
Sbjct: 62 AIQGDVTQAHEVAAAVAGAHVVIHTAGL-VDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
Query: 138 VPRLIYTSTVNVA---FGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMP 194
L+YTS++ V G P +G+ED+ PY + H Y +KA+A+ L L ANG
Sbjct: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDT-PYEAVHRHP--YPCSKALAEWLVLEANGRK 177
Query: 195 LPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQA 254
+ GG L TC LRP GIYG Q ++ ++FR V+V N+
Sbjct: 178 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM 237
Query: 255 HVLAAEALTTAKGYVASGQAYYINDG------ESVNLFEWMAPLFEKLGYSQPWIQVPTS 308
HVLAA L + + GQ Y+ DG E N+ E++ P +L ++P + P
Sbjct: 238 HVLAAREL-EQRATLMGGQVYFCYDGSPYRSYEDFNM-EFLGPCGLRLVGARPLL--PYW 293
Query: 309 WVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFAD 368
+ AA+ L LRP+ PLL + T T KA+ GY P F + D
Sbjct: 294 LLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEP-LFSWED 352
Query: 369 A---VELYVQSTT 378
+ L+VQ+ T
Sbjct: 353 SRTRTILWVQAAT 365
>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 60.1 bits (144), Expect = 4e-09
Identities = 57/185 (30%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGT---SVILLDRRRPQWELSPET-----K 77
A +A + LVTGG G+LG + L + + + D+ W +T
Sbjct: 2 ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVT 61
Query: 78 FIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRR 137
IQ DV + A G V H A + + + I +NV GT+ VI+ CV+
Sbjct: 62 AIQGDVTQAHEVAAAVAGAHVVIHTAGL-VDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
Query: 138 VPRLIYTSTVNVA---FGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMP 194
L+YTS++ V G P +G+ED+ PY + H Y +KA+A+ L L ANG
Sbjct: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDT-PYEAVHRH--PYPCSKALAEWLVLEANGRK 177
Query: 195 --LPG 197
LPG
Sbjct: 178 AMLPG 182
>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 60.1 bits (144), Expect = 4e-09
Identities = 57/185 (30%), Positives = 84/185 (45%), Gaps = 17/185 (9%)
Query: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGT---SVILLDRRRPQWELSPET-----K 77
A +A + LVTGG G+LG + L + + + D+ W +T
Sbjct: 2 ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVT 61
Query: 78 FIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRR 137
IQ DV + A G V H A + + + I +NV GT+ VI+ CV+
Sbjct: 62 AIQGDVTQAHEVAAAVAGAHVVIHTAGL-VDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
Query: 138 VPRLIYTSTVNVA---FGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMP 194
L+YTS++ V G P +G+ED+ PY + H Y +KA+A+ L L ANG
Sbjct: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDT-PYEAVHRH--PYPCSKALAEWLVLEANGRK 177
Query: 195 --LPG 197
LPG
Sbjct: 178 AMLPG 182
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 48.1 bits (113), Expect = 1e-05
Identities = 43/163 (26%), Positives = 76/163 (46%), Gaps = 18/163 (11%)
Query: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPET----------KFIQADV 83
++VLVTGG G++ + L + + ++++ + + S + KFIQ D+
Sbjct: 18 KRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDI 77
Query: 84 RDEEALYRAFEG--VDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRL 141
D + FE +D V H A+ ++ + +NV GT +++ RV +
Sbjct: 78 CDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKF 137
Query: 142 IYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIAD 184
IY ST V +GG ++ DE S P P + Y+ +KA A+
Sbjct: 138 IYVSTDEV-YGGSLDKEFDESS-PKQP----TNPYASSKAAAE 174
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78
+KVLVTGG GY+G L ++G +++D RR Q +F
Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
Query: 79 IQADVRDEEALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136
+ D+ D+ AL R F+ V H A G + +N+ GT ++++
Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
Query: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171
V L+++S+ V G P Y PLDE
Sbjct: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78
+KVLVTGG GY+G L ++G +++D RR Q +F
Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
Query: 79 IQADVRDEEALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136
+ D+ D+ AL R F+ V H A G + +N+ GT ++++
Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
Query: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171
V L+++S+ V G P Y PLDE
Sbjct: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78
+KVLVTGG GY+G L ++G +++D RR Q +F
Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
Query: 79 IQADVRDEEALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136
+ D+ D+ AL R F+ V H A G + +N+ GT ++++
Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
Query: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171
V L+++S+ V G P Y PLDE
Sbjct: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
>gi|10190720 NmrA-like family domain containing 1 [Homo sapiens]
Length = 299
Score = 36.2 bits (82), Expect = 0.058
Identities = 29/122 (23%), Positives = 56/122 (45%), Gaps = 13/122 (10%)
Query: 33 RQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKF-----IQADVRDEE 87
++ V+V GG G G S+ L + GT + + R P+ + + E + +Q D D+
Sbjct: 4 KKLVVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRKKAAKELRLQGAEVVQGDQDDQV 63
Query: 88 ALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTSTV 147
+ A G F V +Y S +++ + +Q KL+ D+ R + ++Y+
Sbjct: 64 IMELALNGAYATFIVTNYWESCSQEQEVKQ--------GKLLADLARRLGLHYVVYSGLE 115
Query: 148 NV 149
N+
Sbjct: 116 NI 117
>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
Length = 420
Score = 36.2 bits (82), Expect = 0.058
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 26/143 (18%)
Query: 33 RQKVLVTGGGGYLGFSLGSHLAKSGTSVILLD-------RRRPQWELSPETKFIQADVRD 85
R+++L+TGG G++G L L G V ++D R W + I DV
Sbjct: 88 RKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDV-- 145
Query: 86 EEALYRAFEGVDCVFHVAS------YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVP 139
E LY VD ++H+AS Y + + L+ I ++N+ G +R
Sbjct: 146 VEPLYIE---VDQIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLG-------LAKRVGA 195
Query: 140 RLIYTSTVNVAFGGKPIEQGDED 162
RL+ ST V +G + ED
Sbjct: 196 RLLLASTSEV-YGDPEVHPQSED 217
>gi|31543615 dehydrogenase/reductase (SDR family) member 3 [Homo
sapiens]
Length = 302
Score = 32.0 bits (71), Expect = 1.1
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
Query: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQW---------ELSPET 76
AK +R+ VL+TGGG +G L A+ G I+L R + ++ E
Sbjct: 31 AKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTEC 90
Query: 77 KFIQADVRDEEALYRAFEGV 96
+ DV + E +Y+ + V
Sbjct: 91 HYFICDVGNREEVYQTAKAV 110
>gi|194306651 pyruvate dehydrogenase phosphatase regulatory
subunit [Homo sapiens]
Length = 879
Score = 31.2 bits (69), Expect = 1.9
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 5/67 (7%)
Query: 2 KSNPPRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSG-TSV 60
+++P + + + + A + ++ A PT+A +V GGG G S+ HL+K G +
Sbjct: 14 RASPGWQNWSSARNSTSAAEARSMALPTQAQ----VVICGGGITGTSVAYHLSKMGWKDI 69
Query: 61 ILLDRRR 67
+LL++ R
Sbjct: 70 VLLEQGR 76
>gi|32455239 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 30.0 bits (66), Expect = 4.1
Identities = 14/41 (34%), Positives = 22/41 (53%)
Query: 27 KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRR 67
+P +KV+VTG +G + HLAK G V++ R +
Sbjct: 28 RPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSK 68
>gi|5031765 11-beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 292
Score = 30.0 bits (66), Expect = 4.1
Identities = 14/41 (34%), Positives = 22/41 (53%)
Query: 27 KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRR 67
+P +KV+VTG +G + HLAK G V++ R +
Sbjct: 28 RPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSK 68
>gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9,
39kDa [Homo sapiens]
Length = 377
Score = 30.0 bits (66), Expect = 4.1
Identities = 19/73 (26%), Positives = 38/73 (52%), Gaps = 9/73 (12%)
Query: 38 VTGGGGYLGFSLGSHLAKSGTSVIL--------LDRRRPQWELSPETKFIQADVRDEEAL 89
V G G+LG + +HL + G+ VI+ + RP +L + F++ D RD++++
Sbjct: 58 VFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLG-QLLFLEWDARDKDSI 116
Query: 90 YRAFEGVDCVFHV 102
R + + V ++
Sbjct: 117 RRVVQHSNVVINL 129
>gi|4885371 H1 histone family, member 0 [Homo sapiens]
Length = 194
Score = 30.0 bits (66), Expect = 4.1
Identities = 13/34 (38%), Positives = 22/34 (64%)
Query: 6 PRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVT 39
P+ + + KAA +AP +K +A P K A++K+ T
Sbjct: 120 PKKASKPKKAASKAPTKKPKATPVKKAKKKLAAT 153
>gi|123701326 zinc finger protein 831 [Homo sapiens]
Length = 1677
Score = 30.0 bits (66), Expect = 4.1
Identities = 18/50 (36%), Positives = 23/50 (46%)
Query: 22 QKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWE 71
QK +A P + + + G G LGF L A S +V DRR P E
Sbjct: 633 QKMKASPHGGKKAREVGMGSGAELGFPLQKEAAGSSGTVPTQDRRTPVHE 682
>gi|24797151 dimethylglycine dehydrogenase precursor [Homo
sapiens]
Length = 866
Score = 29.3 bits (64), Expect = 7.0
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 6/61 (9%)
Query: 6 PRSSLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSG-TSVILLD 64
PRS C G+ + K + V++ GGG +G SL HLAK+G V+LL+
Sbjct: 26 PRS---VCGREGEEKPPLSAETQWKDRAETVII--GGGCVGVSLAYHLAKAGMKDVVLLE 80
Query: 65 R 65
+
Sbjct: 81 K 81
>gi|27436951 lamin B2 [Homo sapiens]
Length = 600
Score = 28.9 bits (63), Expect = 9.2
Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Query: 9 SLEACKAAGQAPQQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRP 68
SL A G++ +++ + + + VL TG GG GF L + SG+ I
Sbjct: 404 SLSATGRLGRSKRKRLEVEEPLGSGPSVLGTGTGGSGGFHLAQQASASGSVSI------- 456
Query: 69 QWELSPETKFIQ 80
E+ E KF+Q
Sbjct: 457 -EEIDLEGKFVQ 467
>gi|148664218 POU transcription factor [Homo sapiens]
Length = 436
Score = 28.9 bits (63), Expect = 9.2
Identities = 26/95 (27%), Positives = 46/95 (48%), Gaps = 13/95 (13%)
Query: 252 VQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFE----KLGYSQPWIQVPT 307
++ H+ A++ L K +SG A +D E + F A F+ KLG++Q + +
Sbjct: 160 LEPHLEASQHLPVPKHLPSSGGADEPSDLEELEKF---AKTFKQRRIKLGFTQGDVGLAM 216
Query: 308 SWVY------LTAAVMERLHLALRPICSLPPLLTR 336
+Y T + E L+L+ + +C L PLL +
Sbjct: 217 GKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEK 251
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,455,592
Number of Sequences: 37866
Number of extensions: 746476
Number of successful extensions: 1756
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1708
Number of HSP's gapped (non-prelim): 30
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.