BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans) [Homo sapiens] (503 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans... 1068 0.0 gi|239750109 PREDICTED: similar to unc-93 homolog B1 (C. elegans... 1063 0.0 gi|239755577 PREDICTED: similar to unc-93 homolog B1 (C. elegans... 393 e-109 gi|45580709 unc-93 homolog B1 [Homo sapiens] 369 e-102 gi|239747143 PREDICTED: hypothetical protein XP_002343924 [Homo ... 345 7e-95 gi|110832843 TBP-associated factor 4 [Homo sapiens] 51 2e-06 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 49 1e-05 gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 49 1e-05 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 48 2e-05 gi|163965366 nascent polypeptide-associated complex alpha subuni... 48 2e-05 gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 47 3e-05 gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [... 47 4e-05 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 47 5e-05 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 46 7e-05 gi|146219832 myosin light chain kinase 3 [Homo sapiens] 46 9e-05 gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 45 1e-04 gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 45 1e-04 gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 45 1e-04 gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 45 1e-04 gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 45 1e-04 gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 45 1e-04 gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 45 1e-04 gi|29336077 unc-93 homolog A isoform 1 [Homo sapiens] 45 1e-04 gi|221139828 unc-93 homolog A isoform 2 [Homo sapiens] 45 1e-04 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 45 2e-04 gi|22027541 programmed cell death 7 [Homo sapiens] 44 3e-04 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 44 4e-04 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 44 4e-04 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 44 4e-04 gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 44 4e-04 >gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans) [Homo sapiens] Length = 503 Score = 1068 bits (2763), Expect = 0.0 Identities = 503/503 (100%), Positives = 503/503 (100%) Query: 1 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE 60 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE Sbjct: 1 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE 60 Query: 61 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 120 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP Sbjct: 61 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 120 Query: 121 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE 180 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE Sbjct: 121 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE 180 Query: 181 QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQI 240 QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQI Sbjct: 181 QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQI 240 Query: 241 LPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR 300 LPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR Sbjct: 241 LPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR 300 Query: 301 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG 360 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG Sbjct: 301 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG 360 Query: 361 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV 420 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV Sbjct: 361 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV 420 Query: 421 GLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGA 480 GLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGA Sbjct: 421 GLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGA 480 Query: 481 PSCTPAGPGLAHTIPHSPQPLYP 503 PSCTPAGPGLAHTIPHSPQPLYP Sbjct: 481 PSCTPAGPGLAHTIPHSPQPLYP 503 >gi|239750109 PREDICTED: similar to unc-93 homolog B1 (C. elegans) [Homo sapiens] Length = 529 Score = 1063 bits (2749), Expect = 0.0 Identities = 500/503 (99%), Positives = 502/503 (99%) Query: 1 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE 60 +AGAGVHLLLTFILFFWAPVPRVLQH WILCVAAALWGVGSALNNTGLSTLLGILY+DKE Sbjct: 27 VAGAGVHLLLTFILFFWAPVPRVLQHSWILCVAAALWGVGSALNNTGLSTLLGILYKDKE 86 Query: 61 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 120 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP Sbjct: 87 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 146 Query: 121 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE 180 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE Sbjct: 147 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE 206 Query: 181 QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQI 240 QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQI Sbjct: 207 QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQI 266 Query: 241 LPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR 300 LPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR Sbjct: 267 LPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR 326 Query: 301 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG 360 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG Sbjct: 327 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG 386 Query: 361 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV 420 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV Sbjct: 387 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV 446 Query: 421 GLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGA 480 GLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGA Sbjct: 447 GLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGA 506 Query: 481 PSCTPAGPGLAHTIPHSPQPLYP 503 PSCTPAGPGLAHTIPHSPQPLYP Sbjct: 507 PSCTPAGPGLAHTIPHSPQPLYP 529 >gi|239755577 PREDICTED: similar to unc-93 homolog B1 (C. elegans) [Homo sapiens] Length = 312 Score = 393 bits (1009), Expect = e-109 Identities = 188/191 (98%), Positives = 190/191 (99%) Query: 1 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE 60 +AGAGVHLLLTFILFFWAPVPRVLQH WILCVAAALWGVGSALNNTGLSTLLGILY+DKE Sbjct: 27 VAGAGVHLLLTFILFFWAPVPRVLQHSWILCVAAALWGVGSALNNTGLSTLLGILYKDKE 86 Query: 61 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 120 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP Sbjct: 87 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 146 Query: 121 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE 180 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE Sbjct: 147 QPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYE 206 Query: 181 QAQRGDGPEEH 191 QAQRGDGPEEH Sbjct: 207 QAQRGDGPEEH 217 Score = 106 bits (265), Expect = 4e-23 Identities = 49/49 (100%), Positives = 49/49 (100%) Query: 422 LSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGED 470 LSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGED Sbjct: 218 LSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGED 266 >gi|45580709 unc-93 homolog B1 [Homo sapiens] Length = 597 Score = 369 bits (946), Expect = e-102 Identities = 181/191 (94%), Positives = 184/191 (96%), Gaps = 1/191 (0%) Query: 1 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE 60 +AGAGVHLLLTFILFFWAPVPRVLQH WIL VAAALWGVGSALN TGLSTLLGILYEDKE Sbjct: 406 VAGAGVHLLLTFILFFWAPVPRVLQHSWILYVAAALWGVGSALNKTGLSTLLGILYEDKE 465 Query: 61 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 120 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLA+LLVTLVAAAVSYLRMEQKLRRGVAP Sbjct: 466 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAVLLVTLVAAAVSYLRMEQKLRRGVAPR 525 Query: 121 QPRIPRPQHKVRGYRYL-EDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPY 179 QPRIPRPQHKVRGYRYL EDNS+ESDAE EHGDGAEEEAPPAGPRPGPEPAGLGRRPCPY Sbjct: 526 QPRIPRPQHKVRGYRYLEEDNSDESDAEGEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPY 585 Query: 180 EQAQRGDGPEE 190 EQAQ GDGPEE Sbjct: 586 EQAQGGDGPEE 596 >gi|239747143 PREDICTED: hypothetical protein XP_002343924 [Homo sapiens] Length = 319 Score = 345 bits (884), Expect = 7e-95 Identities = 190/270 (70%), Positives = 199/270 (73%), Gaps = 19/270 (7%) Query: 1 MAGAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKE 60 +AGAGVHLLLTFILFFWAPVPRVLQH WIL VAAALW VGS+LN TGLSTLLGILYEDKE Sbjct: 46 VAGAGVHLLLTFILFFWAPVPRVLQHSWILYVAAALWVVGSSLNKTGLSTLLGILYEDKE 105 Query: 61 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLAMLLVTLVAAAVSYLRMEQKLRRGVAPP 120 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLA+LLVTLVAA VSYLRMEQKLRRGVAP Sbjct: 106 RQDFIFTIYHWWQAVAIFTVYLGSSLHMKAKLALLLVTLVAATVSYLRMEQKLRRGVAPR 165 Query: 121 QPRIPRPQHKVRGYRYL-EDNSEESDAEDEHGDG--AEEEAPPAGPRPGPEPAGLGRRPC 177 QPRIPRPQHKVRGYRYL EDNS+ESDAE + GDG AE EAPPAGPRPGPEPAGLGRRPC Sbjct: 166 QPRIPRPQHKVRGYRYLEEDNSDESDAEGDLGDGEEAEAEAPPAGPRPGPEPAGLGRRPC 225 Query: 178 PYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFE--NTAETLRALSTRPSAGAGSGSSCDP 235 PYEQAQ G G P A + + LR C Sbjct: 226 PYEQAQGAMGRRSSEGPPGPRTQPPSSPASVYHVLGRGDPLRV------------PRCLQ 273 Query: 236 APLQILPAVGRGPGPRVTALCTSYPQGPPR 265 PL LP VG P PR + + PQ PPR Sbjct: 274 RPLSPLPHVGDAP-PRAW-VTSGLPQPPPR 301 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 51.2 bits (121), Expect = 2e-06 Identities = 80/291 (27%), Positives = 101/291 (34%), Gaps = 47/291 (16%) Query: 151 GDGAEEEAPPAGPRP----GPEPAGLGRRPCPYEQAQR-GDGPEEHPLQGGVEPWEPLGQ 205 G G + PP+ RP GP P RP P A P + G EP P G Sbjct: 99 GGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP-APAGP 157 Query: 206 AQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVT-----ALCTSYP 260 A+ A L+ R G G G P P PA GPG T AL S+ Sbjct: 158 AKPAGPAA-----LAARAGPGPGPGPGPGPGPGPGKPA---GPGAAQTLNGSAALLNSHH 209 Query: 261 QGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGV 320 P + L +L P PG ++ P + A A P A + P P Sbjct: 210 AAAP--AVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAA-APPAPAAPSPPAAPAPAAP 266 Query: 321 GSAAPYWGRGEVSVG-PAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRD------RGG 373 +A P ++ P P PP A P +P P +GG+AG GG Sbjct: 267 AAAPPPPPPAPATLARPPGHPAGPPTAAPAVP-----PPAAAQNGGSAGAAPAPAPAAGG 321 Query: 374 CDGVAGPPWVQRARQTP-------------EAHPPGACVGILGPPATIPAS 411 GV+G P A P +A PP A PA+ AS Sbjct: 322 PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372 Score = 36.2 bits (82), Expect = 0.071 Identities = 71/271 (26%), Positives = 85/271 (31%), Gaps = 68/271 (25%) Query: 154 AEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTA 213 A E PAGP PA L R P G GP P G +P P G AQ +A Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGP----GPGPGPGPGPGPGKPAGP-GAAQTLNGSA 202 Query: 214 ETLRA------------------------------LSTRPSAGAGS-----GSSCDPAPL 238 L + + T P GA + S AP Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA 262 Query: 239 QILPAVGRGPGPRVTALCT---SYPQGPPRATIFL------QKMSNKEILYCPYWGVPGR 289 PA P P A +P GPP A + Q + P G Sbjct: 263 PAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322 Query: 290 GGRSA-PGMHARLARPLGAV-------VTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPF 341 G S PG A A P V V Q + ++ P + +GP Q Sbjct: 323 AGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGA 382 Query: 342 LP-PEAPPPIPACLCQPQPGEGSG---GAAG 368 LP P A PP P PG +G GAAG Sbjct: 383 LPSPAAVPP-------PAPGTPTGLPKGAAG 406 Score = 32.7 bits (73), Expect = 0.79 Identities = 54/200 (27%), Positives = 61/200 (30%), Gaps = 49/200 (24%) Query: 295 PGMHARLARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACL 354 P + A A LG V G G G AAP G P AP P PA Sbjct: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGA-------------PGAAPEPPPAGR 94 Query: 355 CQPQPGEGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRV 414 +P G G R GPP +R PP A L PP A Sbjct: 95 ARP-------GGGGPQR------PGPPSPRRPLVPAGPAPPAAK---LRPPPEGSAG--- 135 Query: 415 YFRATVGLSCDAHEKQAGGGADPLQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGP 474 SC A A P P P + PA ++ GP Sbjct: 136 --------SCAPVPAAAAVAAGP---------EPAPAGPAKPAGPAALAARAGPGPGPGP 178 Query: 475 WEGHGAPSCTPAGPGLAHTI 494 G G PAGPG A T+ Sbjct: 179 GPGPGPGPGKPAGPGAAQTL 198 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 48.9 bits (115), Expect = 1e-05 Identities = 88/304 (28%), Positives = 106/304 (34%), Gaps = 64/304 (21%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGD--GAEEEAPPA-----GPRPGPEPAG 171 PP P PR Q V G+ + N E G G + PP GP+ P P G Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624 Query: 172 LGRRPCPYEQAQRGDG--PEEHPLQGGVEPWEPLGQ-----AQGFENTAETLRALSTRPS 224 G +GD P LQG P G+ G + A A + Sbjct: 625 PG--------GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676 Query: 225 AGAGSGSSCDPAPLQILPAVGRGPGPRVT--ALCTSYPQGPPRA--TIFLQKMSNKEILY 280 AGA P L P + G GP + P GPP A T LQ Sbjct: 677 AGAPGERG--PPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ--------- 725 Query: 281 CPYWGVPG-RGGRSAPGMHARLARPLGAVVTG-PDLGGPQG----VGSAAPYWGRGEVS- 333 G+PG RGG +PG P G G P GP+G +G P G+ Sbjct: 726 ----GMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781 Query: 334 ---------VGPAHQPFLPPEAPPPIPACLC-----QPQPG-EGSGGAAG-RDRGGCDGV 377 GP P E PP PA +PG +G GA G + GG GV Sbjct: 782 GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841 Query: 378 AGPP 381 AGPP Sbjct: 842 AGPP 845 Score = 40.4 bits (93), Expect = 0.004 Identities = 79/284 (27%), Positives = 89/284 (31%), Gaps = 60/284 (21%) Query: 143 ESDAEDEHGDGAEEEAP----PAGPRPGPEPAG-LGRRPCPYEQAQRGDGPEEHPLQGGV 197 E A G E AP PAGP P G G R P RG E P + GV Sbjct: 472 EPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE--PGRDGV 529 Query: 198 EPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRG--PGPRVTAL 255 P P + P + G GS P P GR PGP Sbjct: 530 -PGGP---------------GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP----- 568 Query: 256 CTSYPQGPPRATIFLQKMSNKEILYCPYWGVPG----RGGRSAPGMHARLAR-------- 303 S P+G P F N G PG RGG PG + Sbjct: 569 --SGPRGQPGVMGFPGPKGND--------GAPGKNGERGGPGGPGPQGPPGKNGETGPQG 618 Query: 304 PLGAVVTGPDLG--GPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPGE 361 P G G D G GP G G G GP + P E P A G+ Sbjct: 619 PPGPTGPGGDKGDTGPPGPQGLQGLPGTG----GPPGENGKPGEPGPKGDAGAPGAPGGK 674 Query: 362 GSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPP 405 G GA G G G+AG P ++ P G GPP Sbjct: 675 GDAGAPGER--GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPP 716 Score = 38.1 bits (87), Expect = 0.019 Identities = 80/269 (29%), Positives = 94/269 (34%), Gaps = 45/269 (16%) Query: 160 PAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL 219 P P EP G G R P E+ + G P GG P P G QG + R Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP-PGGSGPAGPPG-PQGVKGE----RGS 865 Query: 220 STRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEIL 279 P A G+ P P P PGP P G P N Sbjct: 866 PGGPGAAGFPGARGLPGP----PGSNGNPGP-------PGPSGSPGKDGPPGPAGNTGAP 914 Query: 280 YCPYWGVPG-------RGGRSAPGMHA--RLARPLG-AVVTGP-DLGGPQGV----GSAA 324 P GV G G + +PG PLG A +TG L GP G+ GS Sbjct: 915 GSP--GVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG 972 Query: 325 PYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG-EGSGGAAGRD-RGGCDGVAGPPW 382 P +GE A+ L E PP P Q PG G+ G GRD G DG+ G Sbjct: 973 PQGVKGESGKPGANG--LSGERGPPGP----QGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026 Query: 383 VQRAR-QTPEAHPPGA--CVGILGPPATI 408 + E PGA G GPP + Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055 Score = 36.6 bits (83), Expect = 0.055 Identities = 53/175 (30%), Positives = 62/175 (35%), Gaps = 30/175 (17%) Query: 221 TRPSAGAG-SGSSCDPAPLQI--------LPAVGRGPG-PRVTALCTSYPQGPPRATIFL 270 TRP G G G DP P I +P PG P +C S P GP Sbjct: 96 TRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP------- 148 Query: 271 QKMSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGVGSAAPYWGRG 330 Q S + Y GV G PG A P G T G P G P G Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGP-AGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG 207 Query: 331 EVSVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRD-RGGCDGVAGPPWVQ 384 + GP+ P P P PA G G +GR R G G+ GPP ++ Sbjct: 208 QA--GPSGPPGPPGAIGPSGPA---------GKDGESGRPGRPGERGLPGPPGIK 251 Score = 35.4 bits (80), Expect = 0.12 Identities = 79/287 (27%), Positives = 91/287 (31%), Gaps = 46/287 (16%) Query: 152 DGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFEN 211 +G E PAG R P PAG P DG P G+ P P G + Sbjct: 497 NGIPGEKGPAGERGAPGPAG----PRGAAGEPGRDGVPGGPGMRGM-PGSPGGPGSDGKP 551 Query: 212 TAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGR--------------GPGPRVTALCT 257 + S RP SG P + G GPGP+ Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611 Query: 258 SY--PQGPPRATIFLQKMSNKEILYCP----YWGVPGRGGRSAPGMHARLARPLGAVVTG 311 PQGPP T +K P G+PG GG PG + + P G Sbjct: 612 GETGPQGPPGPT---GPGGDKGDTGPPGPQGLQGLPGTGG--PPGENGKPGEP-GPKGDA 665 Query: 312 PDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGR-- 369 G P G G A RG G A P L A PP P G GAAG Sbjct: 666 GAPGAPGGKGDAGAPGERGPP--GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723 Query: 370 ------DRGGCD-----GVAGPPWVQRARQTPEAHPPGACVGILGPP 405 +RGG G G P A P P G +GPP Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770 Score = 33.9 bits (76), Expect = 0.35 Identities = 44/130 (33%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 285 GVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQG-VGSAAPYWGRGEVS-VGPAHQPFL 342 G+PGR G S G R P GP G VG A RGE GPA P Sbjct: 1020 GLPGRDG-SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP 1078 Query: 343 PPEAPPPIPACLCQPQPGEGSGGAAG--RDRG-----GCDGVAGPPWVQRARQTPEAHPP 395 P P + G GAAG RG G G GP Q A +P P Sbjct: 1079 AGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138 Query: 396 GACVGILGPP 405 VG GPP Sbjct: 1139 RGPVGPSGPP 1148 Score = 33.1 bits (74), Expect = 0.61 Identities = 41/138 (29%), Positives = 49/138 (35%), Gaps = 21/138 (15%) Query: 285 GVPG-RGGRSAPGMHARLARPLGAVVTGPDLG-------GPQGVGSAAPYWG----RGEV 332 G PG G R APG R P A G D GP G A + G +GEV Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353 Query: 333 SVGPAHQPF---LPPEAPPPIP----ACLCQPQPGEGSGGAAGRDRGGCDGVAGPPWVQR 385 GPA P P + P P P P +G G+ G G+ G P + Sbjct: 354 --GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMG 411 Query: 386 ARQTPEAHPPGACVGILG 403 AR P G+ G Sbjct: 412 ARGPPGPAGANGAPGLRG 429 >gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] Length = 1489 Score = 48.5 bits (114), Expect = 1e-05 Identities = 108/423 (25%), Positives = 145/423 (34%), Gaps = 68/423 (16%) Query: 125 PRPQHKVR---GYRYLEDNSEESDAEDEHGDGAEEEAPPA-GPRPG-PEPA---GLGRRP 176 P+ + KV G R+ + + G E+ P + GP P EPA L R P Sbjct: 1026 PKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAP 1085 Query: 177 CPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQ-GFENTAETLRALSTRPSAGAGSGSSCDP 235 P +G E P G + P G + G E A P AG S Sbjct: 1086 APSAVVSSRNGGETAP--GPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGR 1143 Query: 236 APLQILPAVGRGPGPRVTA----LCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGG 291 AP+ A G GPG V A + + PQ PP + + + P P Sbjct: 1144 APVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAP 1203 Query: 292 RSAPGMHARLARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAH------------- 338 PG A +R G D G P P R + +GP Sbjct: 1204 EGEPG--APDSRAGGDTALSGD-GDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRL 1260 Query: 339 QPFLPPEAPPPIPACLCQPQPGEGS-GGAAGRDRGGCDGVAGPPWV------QRARQTPE 391 LPP P P + P EG+ GAAG + GG G GP + + E Sbjct: 1261 SLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGA-GAPGPAEEDGEDEDEDEEEDEE 1319 Query: 392 AHPPGACVGILGP--------PATIPASDRVYFRATVGLSCDAHEKQAGGGADP------ 437 A PGA G GP P + ++D R GL K G +P Sbjct: 1320 AAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLL-----KSPRGADEPEDSELE 1374 Query: 438 LQGLKVPFLHPLLLWPEERDTPAMKSSERLGEDKWGPWEGHGAPSCTPAGPGLAHTIPHS 497 + V F + ++ +++TP + S + P EG PS PA P T PH Sbjct: 1375 RKRKMVSFHGDVTVYLFDQETPTNELSVQ------APPEGDTDPSTPPAPP----TPPHP 1424 Query: 498 PQP 500 P Sbjct: 1425 ATP 1427 Score = 32.3 bits (72), Expect = 1.0 Identities = 69/276 (25%), Positives = 89/276 (32%), Gaps = 47/276 (17%) Query: 154 AEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFE--- 210 A E P P RP P + + G L G W+P G+ G Sbjct: 601 APSEVPQLVSETWASPLFPAPRPFPAQSSASGS----FLLSG----WDPEGRGAGETLAG 652 Query: 211 NTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFL 270 + AE L T P +P + ++G GP R C + + + L Sbjct: 653 DPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPL 712 Query: 271 QK------MSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGVGSAA 324 ++ L CP+ R+ G A L P+ + P +G+AA Sbjct: 713 ERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADL--PMAPPASAPPEFLDPLMGAAA 770 Query: 325 P-YWGRGEVSVGPAHQPFLPPEAPPPIPAC--------------LCQPQPGEGSGG---- 365 P Y GRG PA P PP P PA L P P G G Sbjct: 771 PQYPGRGPP---PAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETE 827 Query: 366 ----AAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 G GG G A V R R PE PGA Sbjct: 828 TPFSPEGAFPGG--GAAEEEGVPRPRAPPEPPDPGA 861 Score = 29.3 bits (64), Expect = 8.7 Identities = 38/136 (27%), Positives = 46/136 (33%), Gaps = 15/136 (11%) Query: 117 VAPPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGR-R 175 VA P + P K Y + + G AEEE P PR PEP G R Sbjct: 805 VASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPR-PRAPPEPPDPGAPR 863 Query: 176 PCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDP 235 P P GP E P E +LR TR G ++ + Sbjct: 864 PPPDPGPLPLPGPREKP---------TFVVQVSTEQLLMSLREDVTRNLLGEKGATARET 914 Query: 236 APLQILPAVGRGPGPR 251 P + GRGPG R Sbjct: 915 GPRK----AGRGPGNR 926 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 47.8 bits (112), Expect = 2e-05 Identities = 71/277 (25%), Positives = 96/277 (34%), Gaps = 35/277 (12%) Query: 144 SDAEDEHGDGAEEEAPP--AGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPW- 200 S A++ + D ++EE+P AG GP P G + P + GP P QGG +P Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGP---PPQGGNKPQG 70 Query: 201 -EPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVTALCTSY 259 P G+ QG + R+ + P G P P G+ GP + Sbjct: 71 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNR 128 Query: 260 PQGPPRATIFLQKMSNKEILYCPY------WGVPGRGGRSAPGMHARLARPLGAVVTG-- 311 PQGPP + P G P +GG G +P G G Sbjct: 129 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188 Query: 312 -----PDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPP-------EAPPPIPACLCQPQP 359 P G PQG P + S P +P PP + PPP P +PQ Sbjct: 189 KPQGPPPPGKPQG---PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG---KPQG 242 Query: 360 GEGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPG 396 GG + GPP ++ PPG Sbjct: 243 PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 47.8 bits (112), Expect = 2e-05 Identities = 95/389 (24%), Positives = 126/389 (32%), Gaps = 63/389 (16%) Query: 158 APPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVE--PWEPLGQAQGFENTAET 215 +P P P P G P + +G P PL G P L +G T + Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGS-PAATPLPKGAPTTPAATLPSPKGGPATP-S 1075 Query: 216 LRALSTRPSAGAGS--GSSCDPAPLQI-LPAVGRGPGPRVTALCTSYPQGPPRATIFLQK 272 L+ T P+A S G P+P +P P P+ L T +G P T Sbjct: 1076 LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK-GGLATPPHKGAP-TTPAATP 1133 Query: 273 MSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGVGSAAPYWGRGEV 332 S K L P P +G + P A P G + T P G P + P G Sbjct: 1134 PSPKGGLATP----PPKGAPTTPA--ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187 Query: 333 SVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRDRGGCDGVAGPPWVQRARQTPEA 392 + P P P PP L P P A G+A P + A TP A Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS-PKGAPTTPAA 1246 Query: 393 HPPGACVGILGPP----ATIPASDRVYFRATVGLSCDAHE-----------KQAGG---- 433 PP G PP T PA+ + GL+ H+ GG Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKG--GLATPPHKGAPNPAVVTPPSPKGGPATS 1304 Query: 434 --------------------GADPLQGLKVPFLHPLLLWPEERDTPAMKS---SERLGED 470 G P +G P P + P + TP + + S + G Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTP---PAVTPPSPKGTPTLPATTPSSKGGPT 1361 Query: 471 KWGPWEGHGAPSCTPAGPGLAHTIPHSPQ 499 EG P+ TP+ G P SP+ Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPK 1390 Score = 47.0 bits (110), Expect = 4e-05 Identities = 62/252 (24%), Positives = 80/252 (31%), Gaps = 21/252 (8%) Query: 160 PAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL 219 PA P P P P + P+ P P P G Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990 Query: 220 STRPSAGAGSGSSCD---PAPLQILPAVGRGPGPRVTALCTSYPQG---PPRATIFLQKM 273 +T PS G + P P + P P P+ + T +P+G PP AT K Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAVTP-----PSPKGSPAATPFPKGASTPPAATPPSPKG 1045 Query: 274 SNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVS 333 S P +G + P A L P G T G P + P G + Sbjct: 1046 S-------PAATPLPKGAPTTPA--ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPAT 1096 Query: 334 VGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAH 393 P P +PP A PP P P +G+ G P + A TP A Sbjct: 1097 PSPKGAP-MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1155 Query: 394 PPGACVGILGPP 405 PP G+ PP Sbjct: 1156 PPSPKGGLATPP 1167 >gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] Length = 424 Score = 47.4 bits (111), Expect = 3e-05 Identities = 62/243 (25%), Positives = 76/243 (31%), Gaps = 29/243 (11%) Query: 128 QHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDG 187 +H R L + S A+ H A+ PP+ P P G G P G Sbjct: 186 RHGSAAERLLAAQNPLSQADRPHQLFADAPPPPSAPNPVVSSLGSGLPPPGMPPP--GSF 243 Query: 188 PEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRG 247 P P G + P P + + GAG P P Sbjct: 244 PPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPH 303 Query: 248 PGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGG----RSAPGMHARLAR 303 PG L P G L P+ G PG GG R PGM Sbjct: 304 PGMSQMQLAHHGPHG----------------LGHPHAGPPGSGGQPPPRPPPGMPHPGPP 347 Query: 304 PLGAVVTGPDLGGPQG-VGSAAPYWGRGEVSVGPAHQPFLPPEAPP------PIPACLCQ 356 P+G GP G P G G P+ RG + P H PP PP P+P Sbjct: 348 PMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPT 407 Query: 357 PQP 359 P+P Sbjct: 408 PRP 410 Score = 30.8 bits (68), Expect = 3.0 Identities = 26/91 (28%), Positives = 31/91 (34%), Gaps = 12/91 (13%) Query: 159 PPAGPRPGPEPAGLGRRPCPYEQAQRGDGP-EEHPLQGGVEPWEPLGQAQGFENTAETLR 217 PP P PGP P G+ R P+ GP H ++G PL G+ Sbjct: 338 PPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGP----PPLMPPHGYTGPPRP-- 391 Query: 218 ALSTRPSAGAGSGSSCDPAPLQILPAVGRGP 248 P G G P P P RGP Sbjct: 392 -----PPYGYQRGPLPPPRPTPRPPVPPRGP 417 >gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [Homo sapiens] Length = 342 Score = 47.0 bits (110), Expect = 4e-05 Identities = 64/210 (30%), Positives = 76/210 (36%), Gaps = 40/210 (19%) Query: 159 PPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQ---GGVEPWEPLGQAQGFENTAET 215 P PGPE C +EQ RG P LQ GG EP E A Sbjct: 103 PSGDADPGPEGRAAA---CFFEQPPRGRNPGPRALQPVLGGRSHVEPS------ERAAVA 153 Query: 216 LRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSN 275 + +L+ P +GS P PL + + PGP T P RA Sbjct: 154 MPSLAGPPFGAEAAGSGY-PGPLDLRRPMRTVPGPLFTDFVRPLNINPDRAL-------- 204 Query: 276 KEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGVG--SAAPYWGRGEVS 333 G GG S MH PLG + P + QG S + Y G G VS Sbjct: 205 ---------GPEYPGGSS---MHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVS 252 Query: 334 -VGPAHQP--FLPPEAP--PPIPACLCQPQ 358 G QP +LPP P PP+P QPQ Sbjct: 253 EPGGDFQPSYYLPPPPPPLPPLPPLPPQPQ 282 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 46.6 bits (109), Expect = 5e-05 Identities = 72/263 (27%), Positives = 87/263 (33%), Gaps = 51/263 (19%) Query: 151 GDGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFE 210 G G + P GP PG P P Q Q+ P++ P Q P +P Q + Sbjct: 37 GMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP-PPHQPPPHPQPHQ 95 Query: 211 ---------NTAETLRALSTRPSAGAGSG----SSCDPA--PLQILPAVGRGPGPRVTA- 254 ++++ + A P+ G GS SS PA P P G GPGP T Sbjct: 96 QQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP-GSGPGPTPTPP 154 Query: 255 -LCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPD 313 TS P G P T P G A P A V GP Sbjct: 155 PAVTSAPPGAPPPT-------------------PPSSGVPTTPPQAGGPPPPPAAVPGPG 195 Query: 314 LGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRDRGG 373 G QG G P G+ P P L P P P G G RGG Sbjct: 196 PGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKP-----PHRG------GGEPRGG 244 Query: 374 CDGVAGPPWVQRARQTPEAHPPG 396 PP+ Q+ Q P PG Sbjct: 245 RQ--HHPPYHQQHHQGPPPGGPG 265 Score = 30.8 bits (68), Expect = 3.0 Identities = 43/172 (25%), Positives = 49/172 (28%), Gaps = 27/172 (15%) Query: 336 PAHQPFLPP-------EAPPPIPACLCQPQPGEGSGGAAGRDRGGCDGVAGPPWVQRARQ 388 P HQP PP + PPP P +P +G G A G + PP Sbjct: 83 PPHQP--PPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG 140 Query: 389 TPEAHPPGACVGILGPPATIPASDRVYFRATVGLSCDAHEKQAGGGADPLQGLKVPFLHP 448 P PG PPA A QAGG P + P Sbjct: 141 APPGSGPGPTP--TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP---- 194 Query: 449 LLLWPEERDTPAMKSSERLGEDKWGPWEGHGAPSCTPAGPGLAHTIPHSPQP 500 P K G K G G P GPGL+ H P Sbjct: 195 ---------GPGPKQGPGPGGPKGGKMPGGPKPG---GGPGLSTPGGHPKPP 234 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 46.2 bits (108), Expect = 7e-05 Identities = 74/276 (26%), Positives = 96/276 (34%), Gaps = 46/276 (16%) Query: 151 GDGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVE-------PWEPL 203 G+ + PP G G P G + P + + +GP P QGG + P +P Sbjct: 44 GNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGP---PPQGGNQSQGPPPRPGKPE 100 Query: 204 GQAQGFENTAETLRALSTRPSA--GAGSGSSCDPAPLQILPA--------VGRGPGPRVT 253 GQ N ++ +P G S P P P +GP PR Sbjct: 101 GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPR-- 158 Query: 254 ALCTSYPQGPPRATIFLQKMSNKEILYCPY----WGVPGRGGRSAPGMHARLARPLGAVV 309 P+GPP + N+ P+ G P +GG + G R +P G Sbjct: 159 ---PGKPEGPP------PQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGP-- 207 Query: 310 TGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGR 369 P GG Q G P G+ E GP Q P+ PPP P P P EG+ Sbjct: 208 --PPQGGNQSQG-PPPRPGKPE---GPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPP 261 Query: 370 DRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPP 405 G GPP Q P P G G PP Sbjct: 262 PPG---RPQGPPPPGGNPQQPLPPPAGKPQGPPPPP 294 Score = 45.8 bits (107), Expect = 9e-05 Identities = 70/257 (27%), Positives = 92/257 (35%), Gaps = 48/257 (18%) Query: 153 GAEEEAPPAGPRPG-PEPAGLGRRPCPYEQAQ----RGDGPEEHPLQGGVE-------PW 200 G + + PP PRPG PE G+ P Q+Q R PE P QGG + P Sbjct: 86 GNQSQGPP--PRPGKPE----GQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 139 Query: 201 EPLGQAQGFENTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVTALCTSYP 260 +P G N ++ +P G + P P G+ GP + Sbjct: 140 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPP---PHPGKPEGPPPQG--GNQS 194 Query: 261 QGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGG--PQ 318 QGPP + E G P +GG + G R +P G P GG PQ Sbjct: 195 QGPP------PRPGKPE-------GPPPQGGNQSQGPPPRPGKPEGP----PSQGGNKPQ 237 Query: 319 GVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRDRGGCDGVA 378 G P+ G+ + GP Q P+ PPP P PG G G Sbjct: 238 G---PPPHPGKPQ---GPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPP 291 Query: 379 GPPWVQRARQTPEAHPP 395 PP R + P+ PP Sbjct: 292 PPPQGGRPHRPPQGQPP 308 Score = 30.0 bits (66), Expect = 5.1 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 149 EHGDGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQ 205 + G+ + PP P+ P P G ++P P A + GP P QGG P GQ Sbjct: 252 QEGNKPQRPPPPGRPQGPPPPGGNPQQPLP-PPAGKPQGPPPPP-QGGRPHRPPQGQ 306 >gi|146219832 myosin light chain kinase 3 [Homo sapiens] Length = 819 Score = 45.8 bits (107), Expect = 9e-05 Identities = 85/309 (27%), Positives = 112/309 (36%), Gaps = 54/309 (17%) Query: 165 PGPEPAGLGRRPCPYE-QAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRP 223 PGP A G P P + +A+ + P E+ L+ G+E L A G N +L P Sbjct: 230 PGPAQAFPGHLPLPTKVEAKAPETPSEN-LRTGLE----LAPAPGRVNVVSP--SLEVAP 282 Query: 224 SAGAGSGSSC-DPAPLQILPAVGRGPGPR--------VTALCT-SYPQGPPRATIFLQKM 273 AG G+ SS DP PL+ + GPGP+ A T S + PPR +I +Q+M Sbjct: 283 GAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEM 342 Query: 274 SNK-EILY-------------CPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQG 319 E+L P PG+ G G R L A T P P+G Sbjct: 343 DTPGEMLMTGRGSLGPTLTTEAPAAAQPGKQGPPGTG------RCLQAPGTEPGEQTPEG 396 Query: 320 VGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRDRGGCDGVAG 379 +P A + P P+ L + + GA G +G G Sbjct: 397 ARELSPLQESSSPGGVKAEEEQRAGAEPGTRPS-LARSDDNDHEVGALGLQQGKSPGAGN 455 Query: 380 PPWVQ----RARQTPEA---HPPGACVGIL----GPPATIPASDRVY----FRATVGLSC 424 P Q RA EA PPGA G + P P RV + G Sbjct: 456 PEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVKETSISAGYEV 515 Query: 425 DAHEKQAGG 433 HE GG Sbjct: 516 CQHEVLGGG 524 >gi|192807323 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform A [Homo sapiens] Length = 1679 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|192807320 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform F [Homo sapiens] Length = 1613 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|192807318 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform E [Homo sapiens] Length = 1614 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|192807316 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform D [Homo sapiens] Length = 1616 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|192807314 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform C [Homo sapiens] Length = 1617 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|192807312 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|21071056 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 45.4 bits (106), Expect = 1e-04 Identities = 80/299 (26%), Positives = 102/299 (34%), Gaps = 45/299 (15%) Query: 119 PPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEA-----PPAGPRPGPEPAGLG 173 PP P P GY + E H G ++ G R G AG+G Sbjct: 49 PPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGH-AGMG 107 Query: 174 RRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL--STRPSAGAGSGS 231 P P +Q +G +P PLG G E+ + + A S+ P +G G Sbjct: 108 PPPSPMDQHSQG-----YP--------SPLG---GSEHASSPVPASGPSSGPQMSSGPGG 151 Query: 232 S-CDPAPLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRG 290 + D A Q L RGP P RA I KM + + + +G Sbjct: 152 APLDGADPQALGQQNRGPTP-----FNQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQG 206 Query: 291 GRSAPGMHARLAR--PLGAVVTGPDLG---GP-QGVGSAAPYWGRGEVSVGPAHQPFLPP 344 R PGM ++ P TGP G GP G G A P + R GP P P Sbjct: 207 KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPS 266 Query: 345 EAPPPIPACLCQPQPG------EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGA 397 PP +P QP G EG A + P R P A PP A Sbjct: 267 GVPPGMPG---QPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAA 322 >gi|29336077 unc-93 homolog A isoform 1 [Homo sapiens] Length = 457 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 8/106 (7%) Query: 3 GAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKERQ 62 GA H+ L W P H+ + V + LWGV A+ T + L G+L+E + + Sbjct: 326 GAVTHVSCMIALLLWRPRA---DHLAVFFVFSGLWGVADAVWQTQNNALYGVLFE--KSK 380 Query: 63 DFIFTIYHWWQAVAIFTVYLGSSLHM--KAKLAMLLVTLVAAAVSY 106 + F Y W+A+ F + G S+ + KL +LL L V+Y Sbjct: 381 EAAFANYRLWEALG-FVIAFGYSMFLCVHVKLYILLGVLSLTMVAY 425 >gi|221139828 unc-93 homolog A isoform 2 [Homo sapiens] Length = 415 Score = 45.4 bits (106), Expect = 1e-04 Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 8/106 (7%) Query: 3 GAGVHLLLTFILFFWAPVPRVLQHIWILCVAAALWGVGSALNNTGLSTLLGILYEDKERQ 62 GA H+ L W P H+ + V + LWGV A+ T + L G+L+E + + Sbjct: 284 GAVTHVSCMIALLLWRPRA---DHLAVFFVFSGLWGVADAVWQTQNNALYGVLFE--KSK 338 Query: 63 DFIFTIYHWWQAVAIFTVYLGSSLHM--KAKLAMLLVTLVAAAVSY 106 + F Y W+A+ F + G S+ + KL +LL L V+Y Sbjct: 339 EAAFANYRLWEALG-FVIAFGYSMFLCVHVKLYILLGVLSLTMVAY 383 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 44.7 bits (104), Expect = 2e-04 Identities = 85/288 (29%), Positives = 101/288 (35%), Gaps = 66/288 (22%) Query: 152 DGAEEEAPPAGPRPGP-------EPAGLGRRPCPYEQAQRG-DGPE----EHPLQGGVEP 199 DGA+ +A PAGP+ P P +G R P E+ + G GP G P Sbjct: 274 DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333 Query: 200 WEPLGQA--QGFENTAETLRALSTRPSAGA-GSGSSCDPAPLQILPAVGRGPGPRVTALC 256 P G A GF A+ + AG G S P ++ P PGP A Sbjct: 334 PGPTGPAGPPGFPG------AVGAKGEAGPQGPRGSEGPQGVRGEPGP---PGPAGAA-- 382 Query: 257 TSYPQGPPRATIFLQKMSNKEILYCPYWGVPG-RGGRSAPGMHARLARPLGAVVTGPD-L 314 P G P A G PG +G APG+ P +GP Sbjct: 383 --GPAGNPGAD-----------------GQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Query: 315 GGPQGV----------GSAAPYWGRGE---VSV----GPAHQPFLPPEAPPPIPACLCQP 357 GGP G GS +GE V V GPA + P P L P Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483 Query: 358 QPGEGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPP 405 PGE GG R G DGVAGP R +P P G G P Sbjct: 484 -PGE-RGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529 Score = 35.8 bits (81), Expect = 0.093 Identities = 77/283 (27%), Positives = 90/283 (31%), Gaps = 62/283 (21%) Query: 152 DGAEEEAPPAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWE-----PLGQA 206 DG P GP P PAG P ++ + G P P + P G A Sbjct: 760 DGVRGLTGPIGP---PGPAG-----APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPA 811 Query: 207 QGFENT--AETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGPRVTALCTSYPQG-- 262 GF A+ P G + P P PA GP V A +G Sbjct: 812 -GFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAG--PAGPPGPIGNVGAPGAKGARGSA 868 Query: 263 -PPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGVG 321 PP AT G PG GR P + A P G GG G Sbjct: 869 GPPGAT-----------------GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRG 911 Query: 322 SAAPYWGRGEVS----VGPAHQPFLP----PEAPPPIPACLCQPQPGEGSGGAAG----R 369 P GEV GPA + P P P P PQ G G G R Sbjct: 912 ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG----PQGIAGQRGVVGLPGQR 967 Query: 370 DRGGCDGVAGPPWVQRARQTP-----EAHPPGAC--VGILGPP 405 G G+ GP + +Q P E PPG G+ GPP Sbjct: 968 GERGFPGLPGPSG-EPGKQGPSGASGERGPPGPMGPPGLAGPP 1009 Score = 35.4 bits (80), Expect = 0.12 Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 18/134 (13%) Query: 285 GVPGRGGRSAPGMHARLARPLGAVVTGPDLGGPQGV-GSAAPYWGRGEVSV--------- 334 G G G + P A P+GA GP GPQG G +G+ + Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGA--RGP--AGPQGPRGDKGETGEQGDRGIKGHRGFSGL 1116 Query: 335 -GPAHQPFLPPEAPPPIPACLCQPQPGEGSGGAAGRD-RGGCDGVAGPPWVQ-RARQTPE 391 GP P P E P + P+ GS GA G+D G G GPP + R Sbjct: 1117 QGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGP 1176 Query: 392 AHPPGACVGILGPP 405 PPG G GPP Sbjct: 1177 VGPPGP-PGPPGPP 1189 Score = 35.0 bits (79), Expect = 0.16 Identities = 73/250 (29%), Positives = 85/250 (34%), Gaps = 61/250 (24%) Query: 160 PAGPRPGPEPAGLGRRPCPYEQAQRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRAL 219 P GP P P GLG P Q G +E GG+ P+G + R L Sbjct: 143 PPGPPGPPGPPGLGGNFAP----QLSYGYDEKS-TGGISVPGPMGPSGP--------RGL 189 Query: 220 STRPSAGAGSGSSCDPA-PLQILPAVGRGPGPRVTALCTSYPQGPPRATIFLQKMSNKEI 278 P A G P P + P GPR P GPP + + E Sbjct: 190 PGPPGAPGPQGFQGPPGEPGE--PGASGPMGPR-------GPPGPPG-----KNGDDGEA 235 Query: 279 LYCPYWGVPGR-GGRSAPGMHARLARPLGAVVTGPDLGGPQGV-------GSAAPYWGRG 330 G PGR G R PG AR L P + G +G G A P Sbjct: 236 ------GKPGRPGERGPPGPQG--ARGLPGTAGLPGMKGHRGFSGLDGAKGDAGP----- 282 Query: 331 EVSVGPAHQPFLPPEAPPP---IPACLCQPQPGEGSGGAAG-RDRGGCDGVAGPPWVQRA 386 GP +P P E P P L + G+ G AG R G G AGPP Sbjct: 283 ---AGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP----- 334 Query: 387 RQTPEAHPPG 396 T A PPG Sbjct: 335 GPTGPAGPPG 344 Score = 33.1 bits (74), Expect = 0.61 Identities = 70/266 (26%), Positives = 89/266 (33%), Gaps = 44/266 (16%) Query: 146 AEDEHGD-GAEEEAPPAGPR-PGPEPAGLGRRPCPYEQAQRGD----GPEEHP-LQGGVE 198 A+ E GD GA+ +A P GP P P +G P + RG G P G V Sbjct: 825 AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884 Query: 199 PWEPLGQA--QGFENTAETLRALSTRPSAGAGSGSSCDPA--PLQILPAVGRGPGPRVTA 254 P P G A G A G G PA P ++ P GP + Sbjct: 885 PPGPSGNAGPPGPPGPAGK--------EGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS 936 Query: 255 LCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPG-RGGRSAPGMHARLARPLGAVVTG-- 311 P G P T Q ++ + + G+PG RG R PG+ P +G Sbjct: 937 PGADGPAGAP-GTPGPQGIAGQRGVV----GLPGQRGERGFPGLPGPSGEPGKQGPSGAS 991 Query: 312 -----------PDLGGP------QGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACL 354 P L GP +G A GR + P PP P Sbjct: 992 GERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAP 1051 Query: 355 CQPQPGEGSGGAAGRDRGGCDGVAGP 380 P P +G + R G G AGP Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGP 1077 >gi|22027541 programmed cell death 7 [Homo sapiens] Length = 485 Score = 43.9 bits (102), Expect = 3e-04 Identities = 56/181 (30%), Positives = 68/181 (37%), Gaps = 34/181 (18%) Query: 242 PAVGRG-PGPRVTALCTSYPQGPPRATIFLQKMSNKEILYCPYWGVPGRGGRSAPGMHAR 300 P G+G PGP PQ PP A + P +P R G PG A Sbjct: 5 PFFGQGRPGPPP-------PQPPPPAPFGCPPPPLPSPAFPP--PLPQRPG-PFPGASAP 54 Query: 301 LARPLGAVVTGPDLGGPQGVGSAAPYWGRGEVSVGPAHQPFLPPEAPPPIPACLCQPQPG 360 +P A+ +G G A ++ P PP PPP P C+P PG Sbjct: 55 FLQPPLALQPRASAEASRGGGGAGAFY------------PVPPPPLPPPPPQ--CRPFPG 100 Query: 361 EGSGGAAGRDRGGCDGVAGPPWVQRARQTPEAHPPGACVGILGPPATIPASDRVYFRATV 420 +G R R G GPPW R PEA PP A +LG A DR + A Sbjct: 101 TDAG---ERPRPPPPG-PGPPWSPR---WPEAPPPPA--DVLGDAALQRLRDRQWLEAVF 151 Query: 421 G 421 G Sbjct: 152 G 152 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 12/145 (8%) Query: 114 RRGVAPPQPRIPRPQ-HKVRGYRYLEDN---SEESDAEDEHGDGAEEEAPPAGPRPGPEP 169 R+G AP P P K + + ED+ SEESD+E+E A +A P+G P Sbjct: 306 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE----APAQAKPSGKAPQVRA 361 Query: 170 AGLGRRPCPYEQA----QRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSA 225 A + P + A R GP +Q G + + ++ ++ E L A++ Sbjct: 362 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVK 421 Query: 226 GAGSGSSCDPAPLQILPAVGRGPGP 250 G PA + +G+G GP Sbjct: 422 PLGKSPQVKPASTMGMGPLGKGAGP 446 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 12/145 (8%) Query: 114 RRGVAPPQPRIPRPQ-HKVRGYRYLEDN---SEESDAEDEHGDGAEEEAPPAGPRPGPEP 169 R+G AP P P K + + ED+ SEESD+E+E A +A P+G P Sbjct: 383 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE----APAQAKPSGKAPQVRA 438 Query: 170 AGLGRRPCPYEQA----QRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSA 225 A + P + A R GP +Q G + + ++ ++ E L A++ Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVK 498 Query: 226 GAGSGSSCDPAPLQILPAVGRGPGP 250 G PA + +G+G GP Sbjct: 499 PLGKSPQVKPASTMGMGPLGKGAGP 523 Score = 30.0 bits (66), Expect = 5.1 Identities = 37/160 (23%), Positives = 54/160 (33%), Gaps = 41/160 (25%) Query: 112 KLRRGVAPPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPP----------- 160 +++ G PP R +P+ EES++ +E G +EEEAP Sbjct: 251 QVKGGALPPAKRAKKPE-------------EESESSEE-GSESEEEAPAGTRSQVKASEK 296 Query: 161 -----AGPRPGPEPAGLGRRPCPYEQA-----QRGDGPEEHPLQGGVEPWEPLGQAQGFE 210 A P G G P P +A Q G E + E ++ E Sbjct: 297 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE------ESSDSE 350 Query: 211 NTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGP 250 +AL ++G S AP + P G P P Sbjct: 351 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 12/145 (8%) Query: 114 RRGVAPPQPRIPRPQ-HKVRGYRYLEDN---SEESDAEDEHGDGAEEEAPPAGPRPGPEP 169 R+G AP P P K + + ED+ SEESD+E+E A +A P+G P Sbjct: 383 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE----APAQAKPSGKAPQVRA 438 Query: 170 AGLGRRPCPYEQA----QRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSA 225 A + P + A R GP +Q G + + ++ ++ E L A++ Sbjct: 439 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVK 498 Query: 226 GAGSGSSCDPAPLQILPAVGRGPGP 250 G PA + +G+G GP Sbjct: 499 PLGKSPQVKPASTMGMGPLGKGAGP 523 Score = 30.0 bits (66), Expect = 5.1 Identities = 37/160 (23%), Positives = 54/160 (33%), Gaps = 41/160 (25%) Query: 112 KLRRGVAPPQPRIPRPQHKVRGYRYLEDNSEESDAEDEHGDGAEEEAPP----------- 160 +++ G PP R +P+ EES++ +E G +EEEAP Sbjct: 251 QVKGGALPPAKRAKKPE-------------EESESSEE-GSESEEEAPAGTRSQVKASEK 296 Query: 161 -----AGPRPGPEPAGLGRRPCPYEQA-----QRGDGPEEHPLQGGVEPWEPLGQAQGFE 210 A P G G P P +A Q G E + E ++ E Sbjct: 297 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE------ESSDSE 350 Query: 211 NTAETLRALSTRPSAGAGSGSSCDPAPLQILPAVGRGPGP 250 +AL ++G S AP + P G P P Sbjct: 351 EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390 >gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo sapiens] Length = 1411 Score = 43.5 bits (101), Expect = 4e-04 Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 12/145 (8%) Query: 114 RRGVAPPQPRIPRPQ-HKVRGYRYLEDN---SEESDAEDEHGDGAEEEAPPAGPRPGPEP 169 R+G AP P P K + + ED+ SEESD+E+E A +A P+G P Sbjct: 306 RKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEE----APAQAKPSGKAPQVRA 361 Query: 170 AGLGRRPCPYEQA----QRGDGPEEHPLQGGVEPWEPLGQAQGFENTAETLRALSTRPSA 225 A + P + A R GP +Q G + + ++ ++ E L A++ Sbjct: 362 ASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVK 421 Query: 226 GAGSGSSCDPAPLQILPAVGRGPGP 250 G PA + +G+G GP Sbjct: 422 PLGKSPQVKPASTMGMGPLGKGAGP 446 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.139 0.457 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,085,317 Number of Sequences: 37866 Number of extensions: 1892717 Number of successful extensions: 14242 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 105 Number of HSP's successfully gapped in prelim test: 714 Number of HSP's that attempted gapping in prelim test: 11892 Number of HSP's gapped (non-prelim): 2774 length of query: 503 length of database: 18,247,518 effective HSP length: 107 effective length of query: 396 effective length of database: 14,195,856 effective search space: 5621558976 effective search space used: 5621558976 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.