Guide to the Human Genome
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Search of human proteins with 239743756

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform
2 [Homo sapiens]
         (1207 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...  2465   0.0  
gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...  1903   0.0  
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]          1868   0.0  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...  1378   0.0  
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...  1256   0.0  
gi|18640734 contactin associated protein-like 5 [Homo sapiens]       1074   0.0  
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...   936   0.0  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...   746   0.0  
gi|239743729 PREDICTED: similar to contactin associated protein-...   723   0.0  
gi|4505463 contactin associated protein 1 precursor [Homo sapiens]    708   0.0  
gi|169184330 PREDICTED: novel protein similar to contactin assoc...   550   e-156
gi|239758135 PREDICTED: similar to cell recognition molecule CAS...   265   2e-70
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]       166   9e-41
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        164   5e-40
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       164   6e-40
gi|239752499 PREDICTED: similar to cell recognition molecule Cas...   146   1e-34
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]       135   2e-31
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             117   9e-26
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...    90   1e-17
gi|105990535 coagulation factor V precursor [Homo sapiens]             86   2e-16
gi|62420886 discoidin domain receptor family, member 2 precursor...    84   6e-16
gi|62420884 discoidin domain receptor family, member 2 precursor...    84   6e-16
gi|38327632 discoidin domain receptor family, member 1 isoform b...    79   3e-14
gi|83977452 discoidin domain receptor family, member 1 isoform c...    79   3e-14
gi|83977450 discoidin domain receptor family, member 1 isoform a...    79   3e-14
gi|54873613 agrin [Homo sapiens]                                       78   6e-14
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    78   6e-14
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa...    77   8e-14
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap...    77   8e-14
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]            76   2e-13

>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
            [Homo sapiens]
          Length = 1207

 Score = 2465 bits (6388), Expect = 0.0
 Identities = 1207/1207 (100%), Positives = 1207/1207 (100%)

Query: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
            MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
            LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
            KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
            SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK
Sbjct: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
            LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD
Sbjct: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
            SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV
Sbjct: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
            SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV
Sbjct: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420

Query: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480
            LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA
Sbjct: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480

Query: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
            VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL
Sbjct: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540

Query: 541  QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600
            QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN
Sbjct: 541  QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600

Query: 601  PSGLYYIDADGSGPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAA 660
            PSGLYYIDADGSGPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAA
Sbjct: 601  PSGLYYIDADGSGPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAA 660

Query: 661  GAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQK 720
            GAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQK
Sbjct: 661  GAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQK 720

Query: 721  CTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLG 780
            CTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLG
Sbjct: 721  CTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLG 780

Query: 781  PLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIR 840
            PLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIR
Sbjct: 781  PLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIR 840

Query: 841  IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 900
            IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP
Sbjct: 841  IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 900

Query: 901  APADGHVRLQLNSQLFIEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREM 960
            APADGHVRLQLNSQLFIEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREM
Sbjct: 901  APADGHVRLQLNSQLFIEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREM 960

Query: 961  ITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADG 1020
            ITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADG
Sbjct: 961  ITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADG 1020

Query: 1021 QLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAAT 1080
            QLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAAT
Sbjct: 1021 QLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAAT 1080

Query: 1081 SGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLA 1140
            SGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLA
Sbjct: 1081 SGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLA 1140

Query: 1141 GGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESK 1200
            GGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESK
Sbjct: 1141 GGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESK 1200

Query: 1201 VSKKEEC 1207
            VSKKEEC
Sbjct: 1201 VSKKEEC 1207


>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
           [Homo sapiens]
          Length = 1288

 Score = 1903 bits (4930), Expect = 0.0
 Identities = 917/918 (99%), Positives = 917/918 (99%), Gaps = 1/918 (0%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
           MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
           LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
           KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
           SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK
Sbjct: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
           LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
           SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV
Sbjct: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
           SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV
Sbjct: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420

Query: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480
           LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA
Sbjct: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480

Query: 481 VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
           VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL
Sbjct: 481 VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540

Query: 541 QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600
           QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN
Sbjct: 541 QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600

Query: 601 PSGLYYIDADGSGPLGPFLVYCNMT-DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 659
           PSGLYYIDADGSGPLGPFLVYCNMT DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA
Sbjct: 601 PSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 660

Query: 660 AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 719
           AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ
Sbjct: 661 AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720

Query: 720 KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 779
           KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL
Sbjct: 721 KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 780

Query: 780 GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 839
           GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI
Sbjct: 781 GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840

Query: 840 RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 899
           RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ
Sbjct: 841 RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900

Query: 900 PAPADGHVRLQLNSQLFI 917
           PAPADGHVRLQLNSQLFI
Sbjct: 901 PAPADGHVRLQLNSQLFI 918



 Score =  561 bits (1446), Expect = e-159
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
            EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV
Sbjct: 999  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 1058

Query: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
            SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1118

Query: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
            VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP
Sbjct: 1119 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1178

Query: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157
            LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN
Sbjct: 1179 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1238

Query: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1207
            ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 1239 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1288



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)

Query: 334  ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
            E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 757  EHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 816

Query: 394  VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVTAGAG--LND 450
            V F F+T   +G  +F E   G   F+        +++  F  G  P  VT  +    ND
Sbjct: 817  VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 873

Query: 451  GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
             QWH V         ++ VD     +QP  A   V +      + GG      G      
Sbjct: 874  NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG------ 927

Query: 507  LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
               F GC+R + +   A+D  L ++  +    +     C          C +GG C +  
Sbjct: 928  ---FLGCIRSLQLNGVALD--LEERATVTPGVE---PGCAGHCSTYGHLCRNGGRCREKR 979

Query: 567  DTFSCDCLGTGYTGETCHSSL 587
               +CDC  + Y G  C + +
Sbjct: 980  RGVTCDCAFSAYDGPFCSNEI 1000



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
           FK   S+G+ +   G   + I +EL    ++ F  + GN     T+   T       +D 
Sbjct: 821 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 874

Query: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328
            WH V  E      +  VD+     Q A  D    L LN ++  GG        A  ++ 
Sbjct: 875 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 927

Query: 329 FHGCLENLYYNGV 341
           F GC+ +L  NGV
Sbjct: 928 FLGCIRSLQLNGV 940


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 1868 bits (4840), Expect = 0.0
 Identities = 899/918 (97%), Positives = 908/918 (98%), Gaps = 1/918 (0%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
           MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCD+PLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
           LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
           KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
           SEVVYFDGQSALLY LDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK
Sbjct: 181 SEVVYFDGQSALLYRLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
           LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
           SS LDLNFEISFGGI +PGRSRAF RKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV
Sbjct: 301 SSYLDLNFEISFGGIPTPGRSRAFRRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
           SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGEL+RGSGSFV
Sbjct: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFV 420

Query: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480
           LFLKDGKLKLSLFQ GQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA
Sbjct: 421 LFLKDGKLKLSLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480

Query: 481 VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
           VLIDSGDTYYFGGCL NSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL
Sbjct: 481 VLIDSGDTYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540

Query: 541 QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600
           QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN
Sbjct: 541 QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600

Query: 601 PSGLYYIDADGSGPLGPFLVYCNMT-DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 659
           PSGLYYIDADGSGPLGPFLVYCNMT D+AWTVV+HGGPDAVTLRGAPSGHP SAVSFAYA
Sbjct: 601 PSGLYYIDADGSGPLGPFLVYCNMTADAAWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYA 660

Query: 660 AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 719
           AGAGQLR+AVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ
Sbjct: 661 AGAGQLRSAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720

Query: 720 KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 779
           KCTCGLEGNCIDSQYYCNCDAG+NEWTSDTIVLSQKEHLPVTQIVMTD G+PHSEA YTL
Sbjct: 721 KCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTL 780

Query: 780 GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 839
           GPLLCRGD+SFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI
Sbjct: 781 GPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840

Query: 840 RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 899
           RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ
Sbjct: 841 RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900

Query: 900 PAPADGHVRLQLNSQLFI 917
           PAPADGHVRLQLNSQLFI
Sbjct: 901 PAPADGHVRLQLNSQLFI 918



 Score =  553 bits (1426), Expect = e-157
 Identities = 285/290 (98%), Positives = 288/290 (99%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
            EISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYV
Sbjct: 999  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 1058

Query: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
            SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1118

Query: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
            VNQS KKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP
Sbjct: 1119 VNQSTKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1178

Query: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157
            LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGP DEGEPLVN
Sbjct: 1179 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPADEGEPLVN 1238

Query: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1207
            ADRRDSAV+GGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 1239 ADRRDSAVIGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1288



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 60/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)

Query: 334  ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
            E+L    + +T+  + H      +G +     Q      +F +  SYL  P   GE    
Sbjct: 757  EHLPVTQIVMTDAGRPHSEAAYTLGPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTAD 816

Query: 394  VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVTAGAG--LND 450
            V F F+T   +G  +F E   G   F+        +++  F  G  P  VT  +    ND
Sbjct: 817  VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 873

Query: 451  GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
             QWH V         ++ VD     +QP  A   V +      + GG      G      
Sbjct: 874  NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG------ 927

Query: 507  LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
               F GC+R + +   A+D  L ++  +    +     C          C +GG C +  
Sbjct: 928  ---FLGCIRSLQLNGVALD--LEERATVTPGVE---PGCAGHCSTYGHLCRNGGRCREKR 979

Query: 567  DTFSCDCLGTGYTGETCHSSL 587
               +CDC  + Y G  C + +
Sbjct: 980  RGVTCDCAFSAYDGPFCSNEI 1000



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
           FK   S+G+ +   G   + I +EL    ++ F  + GN     T+   T       +D 
Sbjct: 821 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 874

Query: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328
            WH V  E      +  VD+     Q A  D    L LN ++  GG        A  ++ 
Sbjct: 875 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 927

Query: 329 FHGCLENLYYNGV 341
           F GC+ +L  NGV
Sbjct: 928 FLGCIRSLQLNGV 940


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
           sapiens]
          Length = 1308

 Score = 1378 bits (3567), Expect = 0.0
 Identities = 659/919 (71%), Positives = 760/919 (82%), Gaps = 3/919 (0%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
           M SV  AVLK LLLL TQ W+ V AGN  DCD PL SALP++SFSSSSELSSSHGPGF+R
Sbjct: 1   MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60

Query: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
           LNRRDGAGGW+PLVSNKYQWLQIDLGERMEVTAVATQGGYGSS+WVTSYLLMFSD G NW
Sbjct: 61  LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120

Query: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
           KQYR+E+SIWGF GN NADSVV+YRLQP  +ARFLRF+PL WNP+GRIGMRIEV+GCAY+
Sbjct: 121 KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180

Query: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
           SEVV  DG+S+LLY  D+K L PI+D+ISLKFK MQS+GILLHREG +G+HITL+L + +
Sbjct: 181 SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240

Query: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
           L   +NSG AKLPST   V LTLGSLLDDQHWHSVLI+ L  QVNFTVD+H HHF A+G+
Sbjct: 241 LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300

Query: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
            + ++L++EISFGGI +PG+S +F  ++FHGCLENLYYNGVD+ +LAK+ KPQI+ MGNV
Sbjct: 301 FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360

Query: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
           SFSC QPQ++PVTFLSSRSYLALP  SGE++VS TFQFRTWN+AG LLF ELQ  SG  +
Sbjct: 361 SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420

Query: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA-VQPLV 479
           LFL DGKLK +L+Q G+ P ++TAG  LNDGQWHSVS SAK +H++V VD   A   PL+
Sbjct: 421 LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480

Query: 480 A-VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFR 538
               I SG TYYFGGC   S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F 
Sbjct: 481 GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540

Query: 539 DLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHR 598
           DLQIDSCGI+DRCLP+YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHR
Sbjct: 541 DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600

Query: 599 GNPSGLYYIDADGSGPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAY 658
           GN SG YYID+DGSGPL PFL+YCNMT++AWT+++H G D   +R     +P +   F Y
Sbjct: 601 GNTSGFYYIDSDGSGPLEPFLLYCNMTETAWTIIQHNGSDLTRVRNTNPENPYAGF-FEY 659

Query: 659 AAGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDA 718
            A   QL+A +N AE CEQ     C  +R  + +DGTPLSWWVGRTNET T WGGS PD 
Sbjct: 660 VASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPDL 719

Query: 719 QKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYT 778
           QKCTCGLEGNCIDSQYYCNCDA +NEWT+DT +L+ KEHLPVT+IV+TDTG+ HSEA Y 
Sbjct: 720 QKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAYK 779

Query: 779 LGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDF 838
           LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+ADV FFFKTT SSGVF+ENLGI DF
Sbjct: 780 LGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIADF 839

Query: 839 IRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKM 898
           IRIELR+PT VTFSFDVGNGP E++VQSPT FNDNQWHHVR ERN+K ASLQVDQL  K 
Sbjct: 840 IRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPKT 899

Query: 899 QPAPADGHVRLQLNSQLFI 917
           QPAPADGHV LQLNSQLF+
Sbjct: 900 QPAPADGHVLLQLNSQLFV 918



 Score =  336 bits (861), Expect = 9e-92
 Identities = 175/286 (61%), Positives = 219/286 (76%), Gaps = 4/286 (1%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
            EISAYF +GSS+ Y+FQE+Y LS+NSSS  +S + D+ L+REMI  SFRTTR+PSLLL+V
Sbjct: 999  EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV 1058

Query: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
            SSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E
Sbjct: 1059 SSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIE 1118

Query: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
            ++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGCLSAV+    AP
Sbjct: 1119 IDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAP 1178

Query: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157
            LKAAL PS P  VTV GHV   + C A   + + +RE   R    A  SG +D+ EPL N
Sbjct: 1179 LKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLAN 1234

Query: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1203
            A + DSAV+GG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1235 AIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1280



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 64/268 (23%), Positives = 98/268 (36%), Gaps = 38/268 (14%)

Query: 334  ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
            E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 757  EHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSAD 816

Query: 394  VTFQFRTWNRAGHLLFGELQRGSGSFV-LFLKDGKLKLSLFQAGQSPRNVTAGAG--LND 450
            V+F F+T   +G  L      G   F+ + L+   +    F  G  P  ++  +    ND
Sbjct: 817  VSFFFKTTASSGVFLEN---LGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 873

Query: 451  GQWHSVSFSAKWSHMNVVVDDDTA-VQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
             QWH V         ++ VD  T   QP  A   VL+      + GG      G      
Sbjct: 874  NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG------ 927

Query: 507  LGGFQGCLRLITIGDKAVD-------PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHG 559
               F GC+R + +    +D          VQ G  G        S G         C +G
Sbjct: 928  ---FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG-----HCSSYG-------KLCRNG 972

Query: 560  GECSQSWDTFSCDCLGTGYTGETCHSSL 587
            G+C +    F CDC  + YTG  C + +
Sbjct: 973  GKCRERPIGFFCDCTFSAYTGPFCSNEI 1000


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 1256 bits (3249), Expect = 0.0
 Identities = 609/890 (68%), Positives = 700/890 (78%), Gaps = 51/890 (5%)

Query: 30  DCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERM 89
           DCD PL SALP++SFSSSSELSSSHGPGF+RLNRRDGAGGW+PLVSNKYQWLQIDLGERM
Sbjct: 5   DCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERM 64

Query: 90  EVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPP 149
           EVTAVATQGGYGSS+WVTSYLLMFSD G NWKQYR+E+SIWGF GN NADSVV+YRLQP 
Sbjct: 65  EVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPS 124

Query: 150 FEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVIS 209
            +ARFLRF+PL WNP+GRIGMRIEV+GCAY+SEVV  DG+S+LLY  D+K L PI+D+IS
Sbjct: 125 IKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIIS 184

Query: 210 LKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDD 269
           LKFK MQS+GILLHREG +G+HITL+L + +L   +NSG AKLPST   V LTLGSLLDD
Sbjct: 185 LKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDD 244

Query: 270 QHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSF 329
           QHWHSVLI+ L  QVNFTVD+H HHF A+G+ + ++L++E                    
Sbjct: 245 QHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE-------------------- 284

Query: 330 HGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGE 389
                                       GNVSFSC QPQ++PVTFLSSRSYLALP  SGE
Sbjct: 285 ----------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGE 316

Query: 390 DKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLN 449
           ++VS TFQFRTWN+AG LLF ELQ  SG  +LFL DGKLK +L+Q G+ P ++TAG  LN
Sbjct: 317 EEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELN 376

Query: 450 DGQWHSVSFSAKWSHMNVVVDDDTA-VQPLVAV-LIDSGDTYYFGGCLGNSSGSGCKSPL 507
           DGQWHSVS SAK +H++V VD   A   PL+    I SG TYYFGGC   S GS CKSPL
Sbjct: 377 DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436

Query: 508 GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWD 567
           GGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP+YCEHGGECSQSW 
Sbjct: 437 GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496

Query: 568 TFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTDS 627
           TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSGPL PFL+YCNMT++
Sbjct: 497 TFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMTET 556

Query: 628 AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 687
           AWT+++H G D   +R     +P +   F Y A   QL+A +N AE CEQ     C  +R
Sbjct: 557 AWTIIQHNGSDLTRVRNTNPENPYAGF-FEYVASMEQLQATINRAEHCEQEFTYYCKKSR 615

Query: 688 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 747
             + +DGTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA +NEWT+
Sbjct: 616 LVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWTN 675

Query: 748 DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 807
           DT +L+ KEHLPVT+IV+TDTG+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP 
Sbjct: 676 DTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPT 735

Query: 808 FHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSP 867
           FHGEL+ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQSP
Sbjct: 736 FHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSP 795

Query: 868 TPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917
           T FNDNQWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+
Sbjct: 796 THFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFV 845



 Score =  336 bits (861), Expect = 9e-92
 Identities = 175/286 (61%), Positives = 219/286 (76%), Gaps = 4/286 (1%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
            EISAYF +GSS+ Y+FQE+Y LS+NSSS  +S + D+ L+REMI  SFRTTR+PSLLL+V
Sbjct: 926  EISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFV 985

Query: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
            SSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + INREE VV +E
Sbjct: 986  SSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIE 1045

Query: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
            ++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGCLSAV+    AP
Sbjct: 1046 IDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAP 1105

Query: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157
            LKAAL PS P  VTV GHV   + C A   + + +RE   R    A  SG +D+ EPL N
Sbjct: 1106 LKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLAN 1161

Query: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1203
            A + DSAV+GG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1162 AIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 64/268 (23%), Positives = 98/268 (36%), Gaps = 38/268 (14%)

Query: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
           E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 684 EHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSAD 743

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFV-LFLKDGKLKLSLFQAGQSPRNVTAGAG--LND 450
           V+F F+T   +G  L      G   F+ + L+   +    F  G  P  ++  +    ND
Sbjct: 744 VSFFFKTTASSGVFLEN---LGIADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFND 800

Query: 451 GQWHSVSFSAKWSHMNVVVDDDTA-VQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            QWH V         ++ VD  T   QP  A   VL+      + GG      G      
Sbjct: 801 NQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG------ 854

Query: 507 LGGFQGCLRLITIGDKAVD-------PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHG 559
              F GC+R + +    +D          VQ G  G        S G         C +G
Sbjct: 855 ---FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRG-----HCSSYG-------KLCRNG 899

Query: 560 GECSQSWDTFSCDCLGTGYTGETCHSSL 587
           G+C +    F CDC  + YTG  C + +
Sbjct: 900 GKCRERPIGFFCDCTFSAYTGPFCSNEI 927



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 39/146 (26%), Positives = 63/146 (43%), Gaps = 18/146 (12%)

Query: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFF-LNSGNAKLPSTIAPVTLTLGSL 266
           +S  FK   S+G+ L   G   + I +EL    +V F  + GN     ++   T      
Sbjct: 744 VSFFFKTTASSGVFLENLGI-ADFIRIELRSPTVVTFSFDVGNGPFEISVQSPTH----- 797

Query: 267 LDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGILSPGRSRAF 324
            +D  WH V +E    + +  VD+ T   Q      +  L LN ++  GG        A 
Sbjct: 798 FNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGG-------TAT 850

Query: 325 TRKSFHGCLENLYYNG--VDVTELAK 348
            ++ F GC+ +L  NG  +D+ E A+
Sbjct: 851 RQRGFLGCIRSLQLNGMTLDLEERAQ 876


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score = 1074 bits (2778), Expect = 0.0
 Identities = 516/911 (56%), Positives = 665/911 (72%), Gaps = 8/911 (0%)

Query: 11  VLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGW 70
           VL LL +  W         +CD PLAS L   +FSSSS+L+ +H P  ++LN R G GGW
Sbjct: 10  VLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGW 67

Query: 71  TPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIW 130
           +P  SN  QWLQ+DLG R+E+TAVATQG YGSSDWVTSY LMFSD GRNWKQY++E+SIW
Sbjct: 68  SPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIW 127

Query: 131 GFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQS 190
            F GN NADSVVH++L     ARF+RF+PL WNP G+IGMR+EVYGC+YKS+V  FDG+S
Sbjct: 128 TFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRS 187

Query: 191 ALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNA 250
           +LLY  ++K +  ++DVISLKFK+MQ +G+L H EGQ G+HITLEL KG+L   LN G++
Sbjct: 188 SLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDS 247

Query: 251 KLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEI 310
           K   + +  + TLGSLLDDQHWHSVLIE +  QVNFTVDKHT HF+ KG++  LD+++E+
Sbjct: 248 KARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYEL 307

Query: 311 SFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTV 370
           SFGGI  PG+   F +K+FHGC+ENLYYNGV++ +LAK+ K QI   GNV+FSC +PQ V
Sbjct: 308 SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQI-YTGNVTFSCSEPQIV 366

Query: 371 PVTFL-SSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLK 429
           P+TF+ SS SYL LPG    D +SV+FQFRTWN+ G LL  EL  GSG+ +L L+ G L+
Sbjct: 367 PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILR 426

Query: 430 LSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA--VQPLVAVLIDSGD 487
           L + +  +    +  G+ LNDG WHSVS +A+ + + + +DD+ A        V I SG+
Sbjct: 427 LVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGN 486

Query: 488 TYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 547
           +YYFGGC  N + S C +P+  FQGC+RLI I ++  D I VQQG+LG+F DL ID C I
Sbjct: 487 SYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSI 546

Query: 548 TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 607
            DRCLP+YCEHGG CSQSW TF C+C  T YTG TCH+S+YEQSCE ++H+GN +G +YI
Sbjct: 547 KDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYI 606

Query: 608 DADGSGPLGPFLVYCNMT-DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLR 666
           D+DGSGPLGP  VYCN+T D  WT V+H   +   +RGA    P  A++  Y     QL 
Sbjct: 607 DSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPY-AMALDYGGSMEQLE 665

Query: 667 AAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLE 726
           A ++ +E CEQ +A  C  +R  ++ DGTP +WW+GR+NE H  WGGS P  Q+C CGL+
Sbjct: 666 AVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLD 725

Query: 727 GNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRG 786
            +C+D Q++CNCDA ++EWT+DT  LS K+HLPVTQIV+TDT + +SEA + +GPL C G
Sbjct: 726 ESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYG 785

Query: 787 DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAP 846
           D+ FWN+ SF TE SYLHFP FH E +AD+ FFFKTT  SGVF+ENLGI DFIR+E+ +P
Sbjct: 786 DRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSP 845

Query: 847 TEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGH 906
           +E+TF+ DVGNGP E+ VQSP+  NDNQWH+VRAERN+K  SLQVD LP+  +    +GH
Sbjct: 846 SEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGH 905

Query: 907 VRLQLNSQLFI 917
            RLQLNSQLF+
Sbjct: 906 FRLQLNSQLFV 916



 Score =  204 bits (518), Expect = 5e-52
 Identities = 117/288 (40%), Positives = 172/288 (59%), Gaps = 6/288 (2%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
            E+SA F  G+S+TY FQE Y +++N S   S++Y D   ++E I LSF TT++PSLLL++
Sbjct: 997  EVSAVFEAGTSVTYMFQEPYPVTKNISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFI 1056

Query: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
            +S  ++++ V+L  NGSLQ+RY L++ +    FT D  N A+ ++H +KINRE   + ++
Sbjct: 1057 NSSSQDFVVVLLCKNGSLQVRYHLNKEET-HVFTIDADNFANRRMHHLKINREGRELTIQ 1115

Query: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
            ++Q  +     S   EF  ++SL LGKV E  G D +  +A   GF GC+S+V++   AP
Sbjct: 1116 MDQQLRLSYNFSPEVEFRVIRSLTLGKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAP 1175

Query: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157
            LKAALR +  + VTV G    +   + G    S    +   +   +   G  DE EPL N
Sbjct: 1176 LKAALRHATVAPVTVHG---TLTESSCGFMVDSDVNAVT-TVHSSSDPFGKTDEREPLTN 1231

Query: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKE 1205
            A R DSAV+GGVIAVVIFI+ CI  I  R   Q K +    S++ +KE
Sbjct: 1232 AVRSDSAVIGGVIAVVIFIIFCIIGIMTRFLYQHK-QSHRTSQMKEKE 1278



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 58/229 (25%), Positives = 93/229 (40%), Gaps = 44/229 (19%)

Query: 372 VTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLL-------FGELQRGSGSFVLFLK 424
           V+F +  SYL  P    E    ++F F+T   +G  L       F  L+  S S + F  
Sbjct: 793 VSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSPSEITFAI 852

Query: 425 D---GKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAV 481
           D   G ++L +    QSP      + LND QWH V         ++ VD+      L   
Sbjct: 853 DVGNGPVELVV----QSP------SLLNDNQWHYVRAERNLKETSLQVDN------LPRS 896

Query: 482 LIDSGDTYYFGGCLGNSSG-SGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
             ++ +  +F   L +     G  S   GF GC+R + +  + +D  L ++  + S    
Sbjct: 897 TRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMD--LEERAKVTS---- 950

Query: 541 QIDSCGITDRC------LPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
                G+   C        S C +GG+C +  + + CDC  + Y G  C
Sbjct: 951 -----GVRPGCPGHCSSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFC 994



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 43/148 (29%), Positives = 66/148 (44%), Gaps = 22/148 (14%)

Query: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIK-GKLVFFLNSGNAKLPSTIAPVTLTLGS- 265
           IS  FK    +G+ L   G   + I LE+    ++ F ++ GN        PV L + S 
Sbjct: 815 ISFFFKTTALSGVFLENLGIK-DFIRLEISSPSEITFAIDVGNG-------PVELVVQSP 866

Query: 266 -LLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSN--LDLNFEISFGGILSPGRSR 322
            LL+D  WH V  E    + +  VD      +   +  +  L LN ++  GG  S     
Sbjct: 867 SLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSS----- 921

Query: 323 AFTRKSFHGCLENLYYNG--VDVTELAK 348
              +K F GC+ +L+ NG  +D+ E AK
Sbjct: 922 --RQKGFLGCIRSLHLNGQKMDLEERAK 947


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo
           sapiens]
          Length = 1331

 Score =  936 bits (2420), Expect = 0.0
 Identities = 443/892 (49%), Positives = 609/892 (68%), Gaps = 7/892 (0%)

Query: 31  CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90
           CD PL S LP  +FSSSS +S S+ PG++++N+R GAGGW+P  S+ YQWLQ+D G R +
Sbjct: 35  CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94

Query: 91  VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150
           ++A+ATQG Y SSDWVT Y +++SD GRNWK Y ++ +IW FPGN N+D VV + LQ P 
Sbjct: 95  ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154

Query: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210
            AR++R +PL WN  GRIG+RIEVYGC+Y ++V+ FDG   L Y    K +K ++DVI+L
Sbjct: 155 IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214

Query: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
            FK  +S G++LH EGQ G++ITLEL K KLV  LN G+ +L       ++  GSLLDD 
Sbjct: 215 NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274

Query: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330
           HWHSV+IE     +N T+D+   HF+  G+   LDL++EI+FGGI   G+  + +RK+F 
Sbjct: 275 HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334

Query: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390
           GC+E++ YNGV++T+LA++ K +   +GN+SFSC +P TVPV F ++ SYL +PG   +D
Sbjct: 335 GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393

Query: 391 KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGK--LKLSLFQAGQSPRNVTAGAGL 448
             SV+FQFRTWN  G L+F       G+  + L + K  + +++ Q   S  ++++G+GL
Sbjct: 394 LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453

Query: 449 NDGQWHSVSFSAKWSHMNVVVDDD--TAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP 506
           NDGQWH V F AK +   + +D D  +AV+    + + +G+ Y+FGG L   + S     
Sbjct: 454 NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513

Query: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
              FQGC++LI + D+ V+   V Q   GSF ++ ID C I DRC+P++CEHGG+CSQ+W
Sbjct: 514 QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573

Query: 567 DTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMT- 625
           D+F C C  TGY+G TCH+S+YE SCEA+KH G  S  Y+ID DGSGPLGP  VYCNMT 
Sbjct: 574 DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633

Query: 626 DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGT 685
           D  WT+V H       + G  +    S     Y+A   Q+ A  + AE CEQ ++  C  
Sbjct: 634 DKVWTIVSHDLQMQTPVVGY-NPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKM 692

Query: 686 ARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEW 745
           +R  ++ DG+P +WWVG+ NE H  WGGS P  QKC CG+E NC D +YYCNCDA   +W
Sbjct: 693 SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752

Query: 746 TSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHF 805
             D   LS K+HLPV+Q+V+ DT +  SEA  ++GPL C+GD+++WN+ASF   +SYLHF
Sbjct: 753 RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812

Query: 806 PAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQ 865
             F GE +AD+ F+FKT    GVF+EN+G  DFI++EL++ TEV+FSFDVGNGP E+ V+
Sbjct: 813 STFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVR 872

Query: 866 SPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917
           SPTP ND+QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+
Sbjct: 873 SPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFV 924



 Score =  168 bits (426), Expect = 2e-41
 Identities = 111/303 (36%), Positives = 164/303 (54%), Gaps = 15/303 (4%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVT----LTREMITLSFRTTRSPSL 973
            ++ A+F  G  + Y+FQ   T + +SSS V +          L +E I  SF TT++P +
Sbjct: 1004 DVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCI 1063

Query: 974  LLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 1033
            LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+GQ H V I R E  
Sbjct: 1064 LLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKT 1123

Query: 1034 VMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVR 1091
            + ++++   S    +  SS T FN+ KSL LGKV+E    D +  +  T GFTGCLS V+
Sbjct: 1124 IFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYNTPGFTGCLSRVQ 1183

Query: 1092 FGRAAPLKAALRPSGPS-RVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVD 1150
            F + APLKAALR +  S  V ++G +   + C A   + SP              S   D
Sbjct: 1184 FNQIAPLKAALRQTNASAHVHIQGELVE-SNCGASPLTLSPMSSATDPWHLDHLDSASAD 1242

Query: 1151 ------EGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIR-IYQQRKLRKENESKVSK 1203
                  +G+ + N   R+SA++GGVIAVVIF +LC     IR +++ +     NE+K ++
Sbjct: 1243 FPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAE 1302

Query: 1204 KEE 1206
              E
Sbjct: 1303 SAE 1305



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 56/221 (25%), Positives = 86/221 (38%), Gaps = 23/221 (10%)

Query: 373  TFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV-LFLKDGKLKLS 431
            +F +  SYL      GE    ++F F+T    G  L      G   F+ L LK       
Sbjct: 802  SFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLEN---MGKEDFIKLELKSATEVSF 858

Query: 432  LFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDT- 488
             F  G  P  +   +   LND QWH V+        ++ VD    +   +      G T 
Sbjct: 859  SFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVD---RLPQQIRKAPTEGHTR 915

Query: 489  --YYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG 546
               Y    +G + G        GF GC+R + +    +D  L ++  + S     I  C 
Sbjct: 916  LELYSQLFVGGAGGQQ------GFLGCIRSLRMNGVTLD--LEERAKVTSGF---ISGCS 964

Query: 547  ITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587
                   + CE+GG+C + +  +SCDC  T Y G  C+  +
Sbjct: 965  GHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDV 1005


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
           [Homo sapiens]
          Length = 944

 Score =  746 bits (1926), Expect = 0.0
 Identities = 374/465 (80%), Positives = 383/465 (82%), Gaps = 41/465 (8%)

Query: 494 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 553
           CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP
Sbjct: 187 CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246

Query: 554 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
           SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG
Sbjct: 247 SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306

Query: 614 PLGPFLVYCNMTDSAWTVVR---------------------HGGPDAVTLRGAPSGHPLS 652
           PLGPFLVYCNMTD +   +                       GG      RG P   P  
Sbjct: 307 PLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDPPRCPQW 366

Query: 653 AVSFAY----------AAGAGQ----LRAAVNLAERCEQR-----LALRCGTARRPDSRD 693
           A +             AAG G+    LRAA   A R         L ++  T +     +
Sbjct: 367 APALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFKVAFREE 426

Query: 694 -GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVL 752
            GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAG+NEWTSDTIVL
Sbjct: 427 YGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL 486

Query: 753 SQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 812
           SQKEHLPVTQIVMTD GQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL
Sbjct: 487 SQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 546

Query: 813 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 872
           TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND
Sbjct: 547 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606

Query: 873 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917
           NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI
Sbjct: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 651



 Score =  287 bits (735), Expect = 4e-77
 Identities = 148/153 (96%), Positives = 151/153 (98%)

Query: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977
            EISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYV
Sbjct: 732  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 791

Query: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037
            SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 792  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 851

Query: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG 1070
            VNQSAKKQVILSSGTEFNAVKSLILGKVL  +G
Sbjct: 852  VNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884



 Score =  123 bits (308), Expect = 1e-27
 Identities = 62/64 (96%), Positives = 63/64 (98%)

Query: 1144 GRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1203
            GRSGPVDEGEPLVNADRRDSAV+GGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSK
Sbjct: 881  GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940

Query: 1204 KEEC 1207
            KEEC
Sbjct: 941  KEEC 944



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)

Query: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
           E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 490 EHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 549

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVT--AGAGLND 450
           V F F+T   +G  +F E   G   F+        +++  F  G  P  VT  +    ND
Sbjct: 550 VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606

Query: 451 GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            QWH V         ++ VD     +QP  A   V +      + GG             
Sbjct: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------- 659

Query: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
             GF GC+R + +   A+D  L ++  +    +     C          C +GG C +  
Sbjct: 660 --GFLGCIRSLQLNGVALD--LEERATVMPGVE---PGCAGHCSTYGHLCRNGGRCREKR 712

Query: 567 DTFSCDCLGTGYTGETCHSSL 587
              +CDC  + Y G  C + +
Sbjct: 713 RGVTCDCAFSAYDGPFCSNEI 733



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
           FK   S+G+ +   G   + I +EL    ++ F  + GN     T+   T       +D 
Sbjct: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607

Query: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328
            WH V  E      +  VD+     Q A  D    L LN ++  GG        A  ++ 
Sbjct: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 660

Query: 329 FHGCLENLYYNGV 341
           F GC+ +L  NGV
Sbjct: 661 FLGCIRSLQLNGV 673


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score =  723 bits (1866), Expect = 0.0
 Identities = 352/357 (98%), Positives = 354/357 (99%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
           MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCD+PLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
           LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
           KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
           SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIK K
Sbjct: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKRK 240

Query: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
           LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELL TQVNFTVDKHTHHFQAKGD
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGD 300

Query: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM 357
           SSNLDLNFEISFGGI +PGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM
Sbjct: 301 SSNLDLNFEISFGGIPTPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM 357



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 11/88 (12%)

Query: 394 VTFQFRTWNRAGHLLFGELQRGSG--------SFVLFLKDGKLKLSLFQAGQSPRNVTAG 445
           ++ +F+     G LL  E Q G+           V FL  G  KL    A   P  +T G
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIA---PVTLTLG 264

Query: 446 AGLNDGQWHSVSFSAKWSHMNVVVDDDT 473
           + L+D  WHSV      + +N  VD  T
Sbjct: 265 SLLDDQHWHSVLIELLHTQVNFTVDKHT 292


>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
          Length = 1384

 Score =  708 bits (1827), Expect = 0.0
 Identities = 354/897 (39%), Positives = 530/897 (59%), Gaps = 14/897 (1%)

Query: 31  CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90
           CD  L   L   S  +SS  S    P F+RL+   G  GW+P + +   WLQIDL ++  
Sbjct: 25  CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81

Query: 91  VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150
           + AVATQG + S DWVT Y+L++ D   +W  + +      F GN N  +VV + L   F
Sbjct: 82  IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141

Query: 151 EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210
            AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG  A+ Y   +   + + DV + 
Sbjct: 142 TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201

Query: 211 KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
            FK  + +G+LLH EG  G+++TLEL    L+  ++ G++ +       T++ G +L+DQ
Sbjct: 202 SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261

Query: 271 HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330
           HWH V ++     VNFT+D +   F   GD   L+L+ E+  GG++   R     R +F 
Sbjct: 262 HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321

Query: 331 GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390
           GC+EN+ +N V++ +LA +   +I   G V+F C  P   P+ F    +++ +PG     
Sbjct: 322 GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381

Query: 391 KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLND 450
           +++V+F+FRTW+  G LLF  L  G G   L L +G++ +S+ Q+G+      AG  LND
Sbjct: 382 RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441

Query: 451 GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLGNSSGSGCKSPLG 508
           G WH V+F A+ +H  + +DD    +  V+  +LI +G +Y+FGGC   +S   C S   
Sbjct: 442 GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501

Query: 509 GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568
            F GC+ L+ +  + V+  LV+   LG + ++  D+CGITDRC P+ CEH G C QSWD 
Sbjct: 502 AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561

Query: 569 FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTDS- 627
           F C C  TGY GETCH+ LY++SCEA++  G  SG + ID DGSGPL PF+VYC++ ++ 
Sbjct: 562 FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621

Query: 628 AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 687
           AWTVVRH       + G+    P       + A   ++ A  N ++ CEQ +   C  +R
Sbjct: 622 AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681

Query: 688 RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 747
             ++  G P S+W+GR  E H  WGGS P  Q+C CGL+ +C+D   YCNCDA Q +W +
Sbjct: 682 LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741

Query: 748 DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 807
           D  +L+  +HLPVTQ+V+ DT +  SEA + L PL C GD++ WN+ SF+T  + L FP 
Sbjct: 742 DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800

Query: 808 FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 861
                + DV F+F+T+  SGVF+EN+G         ++R+EL    +V F+FDVGNG   
Sbjct: 801 IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860

Query: 862 VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFI 917
           +TV S    FND++WH VRAE NVK A L+VD  P  ++P P   ++ ++ +  L++
Sbjct: 861 LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYV 917



 Score =  105 bits (261), Expect = 3e-22
 Identities = 55/154 (35%), Positives = 94/154 (61%), Gaps = 4/154 (2%)

Query: 956  LTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFK 1015
            +T E ++ SF T+ +P++LLYVSSF  +Y++V++ ++G+LQ+RY+L    +P  +    +
Sbjct: 1079 VTGEEVSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLRYQLGT--SPYVYQLTTR 1136

Query: 1016 NMADGQLHQVKINREEAVVMVEVNQS--AKKQVILSSGTEFNAVKSLILGKVLEAAGADP 1073
             + DGQ H + I R    + ++V+     +++  L   ++ ++ K+L LG+V+E    DP
Sbjct: 1137 PVTDGQPHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDP 1196

Query: 1074 DTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGP 1107
            + +R  T GF+GCLS VRF   APLK   R   P
Sbjct: 1197 EIQRYNTPGFSGCLSGVRFNNVAPLKTHFRTPRP 1230



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 41/165 (24%), Positives = 58/165 (35%), Gaps = 27/165 (16%)

Query: 433 FQAGQSPRNVTAGAG---LNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVAVLIDSG 486
           F  G    N+T  +     ND +WH V          + VD    V    PL   +    
Sbjct: 852 FDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEY 911

Query: 487 DTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG 546
           D   + G     S    + P   F GCLR + +         V     G     +  S  
Sbjct: 912 DQPLYVG-----SAELKRRP---FVGCLRAMRLNG-------VTLNLEGRANASEGTSPN 956

Query: 547 ITDRC----LPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587
            T  C    LP  C HGG C + +  ++CDC  T + G  C+  +
Sbjct: 957 CTGHCAHPRLP--CFHGGRCVERYSYYTCDCDLTAFDGPYCNHDI 999



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 8/128 (6%)

Query: 394  VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG-LNDGQ 452
            V+F F T +    LL+          VL   DG L+L  +Q G SP         + DGQ
Sbjct: 1084 VSFSFSTSSAPAVLLYVSSFVRDYMAVLIKDDGTLQLR-YQLGTSPYVYQLTTRPVTDGQ 1142

Query: 453  WHSVSFSAKWSHMNVVVDDDTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP------ 506
             HS++ +  + ++ + VD     +   ++L+DS         LG    +G   P      
Sbjct: 1143 PHSINITRVYRNLFIQVDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYN 1202

Query: 507  LGGFQGCL 514
              GF GCL
Sbjct: 1203 TPGFSGCL 1210


>gi|169184330 PREDICTED: novel protein similar to contactin associated
            protein-like 3 (CNTNAP3) [Homo sapiens]
          Length = 291

 Score =  550 bits (1417), Expect = e-156
 Identities = 284/291 (97%), Positives = 289/291 (99%)

Query: 917  IEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLY 976
            ++ISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLY
Sbjct: 1    MKISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLY 60

Query: 977  VSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMV 1036
            VSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMV
Sbjct: 61   VSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMV 120

Query: 1037 EVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAA 1096
            EVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFG AA
Sbjct: 121  EVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGCAA 180

Query: 1097 PLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLV 1156
            PLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLV
Sbjct: 181  PLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLV 240

Query: 1157 NADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1207
            NADRRDSAV+GGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 241  NADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 291


>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 140

 Score =  265 bits (678), Expect = 2e-70
 Identities = 136/138 (98%), Positives = 138/138 (100%)

Query: 929  MTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVI 988
            MTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYVSSFYEEYLSVI
Sbjct: 1    MTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVI 60

Query: 989  LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 1048
            LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL
Sbjct: 61   LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 120

Query: 1049 SSGTEFNAVKSLILGKVL 1066
            SSGTEFNAVKSLILGKVL
Sbjct: 121  SSGTEFNAVKSLILGKVL 138


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score =  166 bits (421), Expect = 9e-41
 Identities = 196/801 (24%), Positives = 319/801 (39%), Gaps = 114/801 (14%)

Query: 183  VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
            V  F G     Y L   P++   D I+L F+ +Q NG++LH  G+  +++ L L  G + 
Sbjct: 289  VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVW 347

Query: 243  FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSV---------------LIELLDTQVNFT 287
              +N G+    + + PV        +D  WH V               ++  L   V  +
Sbjct: 348  LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTIS 403

Query: 288  VDKH-THHFQAKGDSSNLDLNFEISFGGILSPGRSR---AFTRKSFHGCLENLYYNGVD- 342
            VD   T     + D + L  +     GG  SP  +    +    +F GCL+++ Y   D 
Sbjct: 404  VDGILTTTGYTQEDYTMLGSDDFFYIGG--SPNTADLPGSPVSNNFMGCLKDVVYKNNDF 461

Query: 343  ---VTELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVSVTFQF 398
               ++ LAK+  P++ + G++SF C     + PVTF S  +++ALP  S +   S++  F
Sbjct: 462  KLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDF 521

Query: 399  RTWNRAGHLLFGELQRGSGS------------FVLFLKDGKLKLSLFQAGQSPRNVTAGA 446
            RT    G LLF + +R  G             F + L DG L L L       +   +  
Sbjct: 522  RTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSR 581

Query: 447  GLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAV----LIDSGDTYYFGGCLGNSSGSG 502
             +NDG+W  V F       ++ V+  +   P +A     ++D     Y GG      G  
Sbjct: 582  KVNDGEWCHVDFQRDGRKGSISVNSRST--PFLATGDSEILDLESELYLGGL---PEGGR 636

Query: 503  CKSPL----------GGFQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDR 550
               PL           G+ GC+R + I  ++ D   +   QGA+G        S     +
Sbjct: 637  VDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGV---APFCSRETLKQ 693

Query: 551  CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDAD 610
            C  + C +GG C + W+ F CDC+GTG+ G  C                       +  D
Sbjct: 694  CASAPCRNGGVCREGWNRFICDCIGTGFLGRVCERE-----------------ATVLSYD 736

Query: 611  GSGPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVN 670
            GS  +   L     T++    +R     A  L  A +    SA +       GQ++  VN
Sbjct: 737  GSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRE-SADTLRLELDGGQMKLTVN 795

Query: 671  LAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCI 730
            L         LR G A  P     T  +      NE HT     +   +     ++   +
Sbjct: 796  LD-------CLRVGCA--PSKGPETLFAGHKLNDNEWHTV--RVVRRGKSLQLSVDNVTV 844

Query: 731  DSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQ-------IVMTDTGQPH----SEADYTL 779
            + Q              +T +++++  + V           +   GQP+     + D T 
Sbjct: 845  EGQ-MAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITY 903

Query: 780  GPLLCR-GDKSF-WNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-T 836
              L  R G ++   +  +F + +SYL         +  + F FKTT   G+ + N G   
Sbjct: 904  CELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGN 963

Query: 837  DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQ 896
            DFI IEL     + + FD+GNGP  +   S  P NDNQWH+V   R+    ++   ++  
Sbjct: 964  DFIVIEL-VKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDS 1020

Query: 897  KMQPAPADGHVRLQLNSQLFI 917
            +     ++G   L L  +L+I
Sbjct: 1021 RTVTQHSNGARNLDLKGELYI 1041



 Score =  115 bits (289), Expect = 2e-25
 Identities = 113/418 (27%), Positives = 176/418 (42%), Gaps = 20/418 (4%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F + ++ G+++    +   + + LE
Sbjct: 726  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784

Query: 236  LIKGKLVFFLNSGNAKL---PSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHT 292
            L  G++   +N    ++   PS   P TL  G  L+D  WH+V +      +  +VD  T
Sbjct: 785  LDGGQMKLTVNLDCLRVGCAPSK-GPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVT 843

Query: 293  HHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKP 352
               Q  G  +++ L F     GI++  R  +    +F G L  L +NG    +  K    
Sbjct: 844  VEGQMAG--AHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDI 901

Query: 353  QILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGEL 412
                + N  F        PVTF S  SYLAL        + + FQF+T    G LLF   
Sbjct: 902  TYCEL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS- 959

Query: 413  QRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVV-V 469
              G+   V+ L  G +   +F  G  P  +   +   +ND QWH+V  S    +++ + +
Sbjct: 960  GNGNDFIVIELVKGYIHY-VFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKI 1018

Query: 470  DDDTAVQPLVAVL-IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVDP 526
            D  T  Q       +D     Y GG   N   +  K  +   GFQGCL  + +  +  D 
Sbjct: 1019 DSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDL 1078

Query: 527  ILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
            I     AL     ++    G +  C    C + G C Q WD F+CDC  T Y G  C+
Sbjct: 1079 IA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN 1133



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 45/175 (25%), Positives = 74/175 (42%), Gaps = 21/175 (12%)

Query: 961  ITLSFRTTRSPSLLLYVSSFYE-EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 1019
            ++ S RT  + +LLLY+    + ++L ++L + G L++R+ L   + P     D   +AD
Sbjct: 53   LSFSLRTNATRALLLYLDDGGDCDFLELLLVD-GRLRLRFTLSCAE-PATLQLDTP-VAD 109

Query: 1020 GQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAA 1079
             + H V + R+     + V+  A+   + S   E      L +G      G  PD R +A
Sbjct: 110  DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVG------GIPPDVRLSA 163

Query: 1080 TS--------GFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMAR-CAAG 1125
             +         F G L+ ++ G   P  A L   G    T     AP    CA G
Sbjct: 164  LTLSTVKYEPPFRGLLANLKLGERPP--ALLGSQGLRGATADPLCAPARNPCANG 216



 Score = 37.4 bits (85), Expect = 0.087
 Identities = 51/237 (21%), Positives = 86/237 (36%), Gaps = 23/237 (9%)

Query: 386 NSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAG 445
           +SGE    ++F  RT      LL+ +         L L DG+L+L    +   P  +   
Sbjct: 49  SSGE----LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLD 104

Query: 446 AGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGC 503
             + D +WH V  +       + VD +     + +    +      + GG   +   S  
Sbjct: 105 TPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSAL 164

Query: 504 KSPL----GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY--CE 557
                     F+G L  + +G++    +L  QG  G+  D           C P+   C 
Sbjct: 165 TLSTVKYEPPFRGLLANLKLGERP-PALLGSQGLRGATAD---------PLCAPARNPCA 214

Query: 558 HGGECSQ-SWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
           +GG C+  +     CDC  TG+ G+ C    +     AH    +  G       G+G
Sbjct: 215 NGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 9/105 (8%)

Query: 241 LVFFLNSGNAKLPSTIA---PVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQA 297
           L   L  G  +L  T++   P TL L + + D  WH VL+     +    VD      + 
Sbjct: 78  LELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEV 137

Query: 298 KGDSSNLDLNFEISFGGILSPGRSRAFTRKS------FHGCLENL 336
           +     + +  ++  GGI    R  A T  +      F G L NL
Sbjct: 138 RSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANL 182



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 834  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPF-NDNQWHHVRAERNVKGASLQVD 892
            G+ D++++ +   T V   F+VG    ++T+  P    +D ++H VR  R+   A+LQVD
Sbjct: 1186 GLGDYLQLHIDQGT-VGVIFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242

Query: 893  QLP-QKMQPAPADGHVRLQLNSQ 914
              P  +  PA    + RL +  Q
Sbjct: 1243 SWPVNERYPAGNFDNERLAIARQ 1265


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  164 bits (415), Expect = 5e-40
 Identities = 190/805 (23%), Positives = 326/805 (40%), Gaps = 129/805 (16%)

Query: 183  VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
            +  F G     Y L + P++   D I+L FK +Q NG++LH  G+  +++ L L  G + 
Sbjct: 283  IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 341

Query: 243  FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIEL----------------LD----- 281
              +N G+    + + PV        +D  WH V +                  +D     
Sbjct: 342  LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397

Query: 282  ---TQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYY 338
               TQ ++T+      F   G  S  DL           PG        +F GCL+ + Y
Sbjct: 398  TGYTQEDYTMLGSDDFFYVGGSPSTADL-----------PGSP---VSNNFMGCLKEVVY 443

Query: 339  NGVDV----TELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVS 393
               DV    + LAK+  P++ + G V+F C    T+ P+TF +  S+++LP  + +   S
Sbjct: 444  KNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGS 503

Query: 394  VTFQFRTWNRAGHLLF--GELQRGSGS----------FVLFLKDGKLKLSLFQAGQSPRN 441
            ++F FRT    G +LF  G+ +    +          F + + DG L L L     + + 
Sbjct: 504  ISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKI 563

Query: 442  VTAGAGLNDGQWHSVSFSAKWSHMNVVVDD--DTAVQPLVAVLIDSGDTYYFGGCLGNSS 499
                  +NDG+W+ V F        + V+        P  + ++D  D  Y GG   N +
Sbjct: 564  KALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKA 623

Query: 500  GSGCKSPLG------GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDR-CL 552
            G    + +       G+ GC+R + I  ++ D  + Q   + S   ++      T + CL
Sbjct: 624  GLVFPTEVWTALLNYGYVGCIRDLFIDGQSKD--IRQMAEVQSTAGVKPSCSKETAKPCL 681

Query: 553  PSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGS 612
             + C++ G C   W+ + CDC GTGY G +C                       +  DGS
Sbjct: 682  SNPCKNNGMCRDGWNRYVCDCSGTGYLGRSCERE-----------------ATVLSYDGS 724

Query: 613  GPLGPFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLA 672
              +   L     T++    +R     A  +  A +    SA +      AG+++  VNL 
Sbjct: 725  MFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRD-SADTLRLELDAGRVKLTVNL- 782

Query: 673  ERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHT--------SWGGSLPDAQKCTCG 724
                  + + C +++ P+    T  + +    NE HT        S   ++ D Q  T  
Sbjct: 783  ----DCIRINCNSSKGPE----TLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQ 834

Query: 725  LEGNCIDSQYYCNCDAG---QNEWTSD--TIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 779
            + G+    +++ N + G   +  + S   +  +   + L    +   D  + + + DY  
Sbjct: 835  MAGDHTRLEFH-NIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCK-NGDIDY-- 890

Query: 780  GPLLCRGDKSFW------NSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENL 833
                C  +  F       +  +F T++SY+         +  + F FKTT   G+ + N 
Sbjct: 891  ----CELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNS 946

Query: 834  GI-TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD 892
            G   DFI +EL     + + FD+GNG   +   S  P NDNQWH+V   R+   ++L   
Sbjct: 947  GDGNDFIVVEL-VKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTV 1003

Query: 893  QLPQKMQPAPADGHVRLQLNSQLFI 917
            ++  K+      G   L L S L+I
Sbjct: 1004 KIDTKITTQITAGARNLDLKSDLYI 1028



 Score =  120 bits (301), Expect = 8e-27
 Identities = 115/419 (27%), Positives = 182/419 (43%), Gaps = 21/419 (5%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F++ ++ GIL+    +   + + LE
Sbjct: 712  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 770

Query: 236  LIKGKLVFFLNSGNAKLP--STIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVD-KHT 292
            L  G++   +N    ++   S+  P TL  G  L+D  WH+V +      +  TVD +  
Sbjct: 771  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830

Query: 293  HHFQAKGDSSNLDL-NFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHK 351
               Q  GD + L+  N E    GI++  R  +    +F G L++L +NG+   +L K   
Sbjct: 831  MTGQMAGDHTRLEFHNIET---GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGD 887

Query: 352  PQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGE 411
                 + N  F        PVTF +  SY+AL        + + FQF+T +  G +L+  
Sbjct: 888  IDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNS 946

Query: 412  LQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVV 469
               G+   V+ L  G L   +F  G     +   +   LND QWH+V  S   S+++ V 
Sbjct: 947  GD-GNDFIVVELVKGYLHY-VFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVK 1004

Query: 470  DDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVD 525
             D      + A    +D     Y GG    +  S  K      GFQGCL  + +  +  D
Sbjct: 1005 IDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPD 1064

Query: 526  PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
             I     AL     ++    G +  C    C + G C Q WD FSCDC  T ++G  C+
Sbjct: 1065 LI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN 1120



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 34/213 (15%)

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFV--LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDG 451
           ++FQ +T +  G +L+ +   G   F+  +  + G+L+LS       P  + A   +NDG
Sbjct: 54  MSFQLKTRSARGLVLYFD-DEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDG 112

Query: 452 QWHSVSFSAKWSHMNVVVDDDTAVQPLVA-----VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            WHSV    ++ +  + +D   A    V      + + SG   + GG       +  K  
Sbjct: 113 AWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALKLT 170

Query: 507 LGG------FQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDS----------CGITDR 550
           L        F+G +R + +    V P+           ++++D           C   + 
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQVLPV--------DSGEVKLDDEPPNSGGGSPCEAGEE 222

Query: 551 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
                C +GG CS   D   CDC  TG+ G+ C
Sbjct: 223 GEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 799 ETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVG 856
           E  +  FP ++    +++ F  KT  + G+  + ++ G  DF+ + L     +  SF + 
Sbjct: 37  EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 857 NGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQK 897
                 T+ + TP ND  WH VR  R  +  +L +DQ+  K
Sbjct: 97  CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAK 136



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 45/192 (23%), Positives = 78/192 (40%), Gaps = 31/192 (16%)

Query: 705 NETHTSWGGSLPDAQK------CTCGLEGNCIDSQYYCNCDA----GQNEWTSDTIVLSQ 754
           +E   S GGS  +A +      C  G   + +D Q  C+C      G++    D  V   
Sbjct: 206 DEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEG- 264

Query: 755 KEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTA 814
                +  ++M D G+   + +Y           +F  S  F  + S     +   E+T 
Sbjct: 265 -----LAHLMMGDQGKSKGKEEYIA---------TFKGSEYFCYDLSQNPIQSSSDEITL 310

Query: 815 DVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFNDN 873
                FKT   +G+ +      D++ + L+    V+   ++G+G  E  V+     FNDN
Sbjct: 311 S----FKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKFNDN 365

Query: 874 QWHHVRAERNVK 885
            WH V+  RN++
Sbjct: 366 AWHDVKVTRNLR 377



 Score = 34.7 bits (78), Expect = 0.56
 Identities = 37/181 (20%), Positives = 73/181 (40%), Gaps = 16/181 (8%)

Query: 206  DVISLKFKAMQSNGILLHREGQHG--NHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTL 263
            D +++ F  +Q   +L+  +   G  +++ L + +GK+    N G   +    +      
Sbjct: 1150 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES------ 1203

Query: 264  GSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRA 323
             ++++D  +H V            VD        +   +   L    S   I+  G+ + 
Sbjct: 1204 NAIINDGKYHVVRFTRSGGNATLQVDSWP---VIERYPAGRQLTIFNSQATIIIGGKEQG 1260

Query: 324  FTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSF--SCPQPQTVPVTFLSSRSYL 381
               + F G L  LYYNG+ V  +A ++   I ++GNV      P   T   T  + +S +
Sbjct: 1261 ---QPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEM 1317

Query: 382  A 382
            +
Sbjct: 1318 S 1318


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  164 bits (414), Expect = 6e-40
 Identities = 191/801 (23%), Positives = 328/801 (40%), Gaps = 114/801 (14%)

Query: 183  VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
            +  F G     Y L + P++   D I+L FK +Q NG++LH  G+  +++ L L  G + 
Sbjct: 316  IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 374

Query: 243  FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSV---------------LIELLDTQVNFT 287
              +N G+    + + PV        +D  WH V               ++  L   V  +
Sbjct: 375  LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430

Query: 288  VDKH-THHFQAKGDSSNLDLNFEISFGGILS----PGRSRAFTRKSFHGCLENLYYNGVD 342
            VD   T     + D + L  +     GG  S    PG        +F GCL+ + Y   D
Sbjct: 431  VDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSP---VSNNFMGCLKEVVYKNND 487

Query: 343  V----TELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVSVTFQ 397
            V    + LAK+  P++ + G V+F C    T+ P+TF +  S+++LP  + +   S++F 
Sbjct: 488  VRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFD 547

Query: 398  FRTWNRAGHLLF--GELQRGSGS----------FVLFLKDGKLKLSLFQAGQSPRNVTAG 445
            FRT    G +LF  G+ +    +          F + + DG L L L     + +     
Sbjct: 548  FRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALL 607

Query: 446  AGLNDGQWHSVSFSAKWSHMNVVVDD--DTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGC 503
              +NDG+W+ V F        + V+        P  + ++D  D  Y GG   N +G   
Sbjct: 608  KKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF 667

Query: 504  KSPLG------GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDR-CLPSYC 556
             + +       G+ GC+R + I  ++ D  + Q   + S   ++      T + CL + C
Sbjct: 668  PTEVWTALLNYGYVGCIRDLFIDGQSKD--IRQMAEVQSTAGVKPSCSKETAKPCLSNPC 725

Query: 557  EHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLG 616
            ++ G C   W+ + CDC GTGY G +C                       +  DGS  + 
Sbjct: 726  KNNGMCRDGWNRYVCDCSGTGYLGRSCERE-----------------ATVLSYDGSMFMK 768

Query: 617  PFLVYCNMTDSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCE 676
              L     T++    +R     A  +  A +    SA +      AG+++  VNL     
Sbjct: 769  IQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRD-SADTLRLELDAGRVKLTVNL----- 822

Query: 677  QRLALRCGTARRPDSRDGTPLSWWVGRTNETHT--------SWGGSLPDAQKCTCGLEGN 728
              + + C +++ P+    T  + +    NE HT        S   ++ D Q  T  + G+
Sbjct: 823  DCIRINCNSSKGPE----TLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQAMTGQMAGD 878

Query: 729  CIDSQYYCNCDAG---QNEWTSD--TIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLL 783
                +++ N + G   +  + S   +  +   + L    +   D  + + + DY      
Sbjct: 879  HTRLEFH-NIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCK-NGDIDY------ 930

Query: 784  CRGDKSFW------NSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-T 836
            C  +  F       +  +F T++SY+         +  + F FKTT   G+ + N G   
Sbjct: 931  CELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGN 990

Query: 837  DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQ 896
            DFI +EL     + + FD+GNG   +   S  P NDNQWH+V   R+   ++L   ++  
Sbjct: 991  DFIVVEL-VKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDT--SNLHTVKIDT 1047

Query: 897  KMQPAPADGHVRLQLNSQLFI 917
            K+      G   L L S L+I
Sbjct: 1048 KITTQITAGARNLDLKSDLYI 1068



 Score =  120 bits (301), Expect = 8e-27
 Identities = 115/419 (27%), Positives = 182/419 (43%), Gaps = 21/419 (5%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F++ ++ GIL+    +   + + LE
Sbjct: 752  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 810

Query: 236  LIKGKLVFFLNSGNAKLP--STIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVD-KHT 292
            L  G++   +N    ++   S+  P TL  G  L+D  WH+V +      +  TVD +  
Sbjct: 811  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870

Query: 293  HHFQAKGDSSNLDL-NFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHK 351
               Q  GD + L+  N E    GI++  R  +    +F G L++L +NG+   +L K   
Sbjct: 871  MTGQMAGDHTRLEFHNIET---GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGD 927

Query: 352  PQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGE 411
                 + N  F        PVTF +  SY+AL        + + FQF+T +  G +L+  
Sbjct: 928  IDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNS 986

Query: 412  LQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVV 469
               G+   V+ L  G L   +F  G     +   +   LND QWH+V  S   S+++ V 
Sbjct: 987  GD-GNDFIVVELVKGYLHY-VFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVK 1044

Query: 470  DDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVD 525
             D      + A    +D     Y GG    +  S  K      GFQGCL  + +  +  D
Sbjct: 1045 IDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPD 1104

Query: 526  PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
             I     AL     ++    G +  C    C + G C Q WD FSCDC  T ++G  C+
Sbjct: 1105 LI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN 1160



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 49/217 (22%), Positives = 86/217 (39%), Gaps = 34/217 (15%)

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFV--LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDG 451
           ++FQ +T +  G +L+ +   G   F+  +  + G+L+LS       P  + A   +NDG
Sbjct: 54  MSFQLKTRSARGLVLYFD-DEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDG 112

Query: 452 QWHSVSFSAKWSHMNVVVDDDTAVQPLVA-----VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            WHSV    ++ +  + +D   A    V      + + SG   + GG       +  K  
Sbjct: 113 AWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALKLT 170

Query: 507 LGG------FQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDS----------CGITDR 550
           L        F+G +R + +    V P+           ++++D           C   + 
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQVLPV--------DSGEVKLDDEPPNSGGGSPCEAGEE 222

Query: 551 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587
                C +GG CS   D   CDC  TG+ G+ C   +
Sbjct: 223 GEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 3/101 (2%)

Query: 799 ETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVG 856
           E  +  FP ++    +++ F  KT  + G+  + ++ G  DF+ + L     +  SF + 
Sbjct: 37  EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 857 NGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQK 897
                 T+ + TP ND  WH VR  R  +  +L +DQ+  K
Sbjct: 97  CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAK 136



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 51/210 (24%), Positives = 85/210 (40%), Gaps = 34/210 (16%)

Query: 705 NETHTSWGGSLPDAQK------CTCGLEGNCIDSQYYCNCDAG--QNEWTSDTIVLSQKE 756
           +E   S GGS  +A +      C  G   + +D Q  C+C     + +  S  I    + 
Sbjct: 206 DEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEIKFGLQC 265

Query: 757 HLPVT-------QIVMTDTGQPHSEADYTLGPL--LCRGDK-----------SFWNSASF 796
            LPV        +    +T +P +E D  +  L  L  GD+           +F  S  F
Sbjct: 266 VLPVLLHDNDQGKYCCINTAKPLTEKDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYF 325

Query: 797 NTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVG 856
             + S     +   E+T      FKT   +G+ +      D++ + L+    V+   ++G
Sbjct: 326 CYDLSQNPIQSSSDEITLS----FKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLG 380

Query: 857 NGPCEVTVQSPT-PFNDNQWHHVRAERNVK 885
           +G  E  V+     FNDN WH V+  RN++
Sbjct: 381 SGAFEALVEPVNGKFNDNAWHDVKVTRNLR 410



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 329  FHGCLENLYYNGVDVTELAKKHKPQILMMGNVSF--SCPQPQTVPVTFLSSRSYLA 382
            F G L  LYYNG+ V  +A ++   I ++GNV      P   T   T  + +S ++
Sbjct: 1333 FQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMS 1388



 Score = 31.6 bits (70), Expect = 4.8
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 3/82 (3%)

Query: 834  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ 893
            G+ D++ + +    ++   F+VG     +  +S    ND ++H VR  R+   A+LQVD 
Sbjct: 1213 GLGDYLELHIHQG-KIGVKFNVGTDDIAIE-ESNAIINDGKYHVVRFTRSGGNATLQVDS 1270

Query: 894  LPQ-KMQPAPADGHVRLQLNSQ 914
             P  +  PA  + + RL +  Q
Sbjct: 1271 WPVIERYPAGNNDNERLAIARQ 1292


>gi|239752499 PREDICTED: similar to cell recognition molecule Caspr2,
            partial [Homo sapiens]
          Length = 140

 Score =  146 bits (368), Expect = 1e-34
 Identities = 74/74 (100%), Positives = 74/74 (100%)

Query: 993  GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 1052
            GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT
Sbjct: 2    GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 61

Query: 1053 EFNAVKSLILGKVL 1066
            EFNAVKSLILGKVL
Sbjct: 62   EFNAVKSLILGKVL 75


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score =  135 bits (341), Expect = 2e-31
 Identities = 119/446 (26%), Positives = 191/446 (42%), Gaps = 60/446 (13%)

Query: 183 VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
           V  F G     Y L   P++   D I+L F+ +Q NG++LH  G+  +++ L L  G + 
Sbjct: 265 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVW 323

Query: 243 FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIE--------LLDTQVNFTVDKH-TH 293
             +N G+    + + PV        +D  WH V +         +    V  +VD   T 
Sbjct: 324 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT 379

Query: 294 HFQAKGDSSNLDLNFEISFGGILSPGRSR---AFTRKSFHGCLENLYYNGVD----VTEL 346
               + D + L  +     GG  SP  +    +    +F GCL+++ Y   D    ++ L
Sbjct: 380 TGYTQEDYTMLGSDDFFYIGG--SPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRL 437

Query: 347 AKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAG 405
           AK+  P++ + G++SF C     + PVTF S  +++ALP  S +   S++  FRT    G
Sbjct: 438 AKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNG 497

Query: 406 HLLFGELQRGSGS------------FVLFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQW 453
            LLF + +R  G             F + L DG L L L       +   +   +NDG+W
Sbjct: 498 LLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEW 557

Query: 454 HSVSFSAKWSHMNVVVDDDTAVQPLVAV----LIDSGDTYYFGGCLGNSSGSGCKSPL-- 507
             V F       ++ V+  +   P +A     ++D     Y GG      G     PL  
Sbjct: 558 CHVDFQRDGRKGSISVNSRST--PFLATGDSEILDLESELYLGGL---PEGGRVDLPLPP 612

Query: 508 --------GGFQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDRCLPSYCE 557
                    G+ GC+R + I  ++ D   +   QGA+G        S     +C  + C 
Sbjct: 613 EVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGV---APFCSRETLKQCASAPCR 669

Query: 558 HGGECSQSWDTFSCDCLGTGYTGETC 583
           +GG C + W+ F CDC+GTG+ G  C
Sbjct: 670 NGGVCREGWNRFICDCIGTGFLGRVC 695



 Score =  118 bits (295), Expect = 4e-26
 Identities = 112/415 (26%), Positives = 173/415 (41%), Gaps = 23/415 (5%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F + ++ G+++    +   + + LE
Sbjct: 695  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753

Query: 236  LIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHF 295
            L  G++   +N G         P TL  G  L+D  WH+V +      +  +VD  T   
Sbjct: 754  LDGGQMKLTVNLGKG-------PETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806

Query: 296  QAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQIL 355
            Q  G  +++ L F     GI++  R  +    +F G L  L +NG    +  K       
Sbjct: 807  QMAG--AHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYC 864

Query: 356  MMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRG 415
             + N  F        PVTF S  SYLAL        + + FQF+T    G LLF     G
Sbjct: 865  EL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS-GNG 922

Query: 416  SGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVV-VDDD 472
            +   V+ L  G +   +F  G  P  +   +   +ND QWH+V  S    +++ + +D  
Sbjct: 923  NDFIVIELVKGYIHY-VFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSR 981

Query: 473  TAVQPLVAVL-IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVDPILV 529
            T  Q       +D     Y GG   N   +  K  +   GFQGCL  + +  +  D I  
Sbjct: 982  TVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIA- 1040

Query: 530  QQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
               AL     ++    G +  C    C + G C Q WD F+CDC  T Y G  C+
Sbjct: 1041 --DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN 1093



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 39/124 (31%), Positives = 61/124 (49%), Gaps = 4/124 (3%)

Query: 795  SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 853
            +F + +SYL         +  + F FKTT   G+ + N G   DFI IEL     + + F
Sbjct: 881  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIEL-VKGYIHYVF 939

Query: 854  DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 913
            D+GNGP  +   S  P NDNQWH+V   R+    ++   ++  +     ++G   L L  
Sbjct: 940  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 997

Query: 914  QLFI 917
            +L+I
Sbjct: 998  ELYI 1001



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 73/331 (22%), Positives = 122/331 (36%), Gaps = 51/331 (15%)

Query: 807  AFHGELTADVCFFFKTTVSSGVFMENLG--ITDFIRIELRAPTEVTFSFDVGNGPCEVTV 864
            A H E   DV   F +  + G+ M        D +R+EL    ++  + ++G GP   T+
Sbjct: 717  AMHTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGG-QMKLTVNLGKGP--ETL 772

Query: 865  QSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQ--------LNSQLF 916
             +    NDN+WH VR  R  K   L VD +  + Q A A  H+RL+        +  + F
Sbjct: 773  FAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHNIETGIMTERRF 830

Query: 917  IEI--SAYFATGSSMTYHFQEH---------------------------YTLSENSSSLV 947
            I +  S +    S + ++ Q +                            T    SS L 
Sbjct: 831  ISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYCELNARFGLRAIVADPVTFKSRSSYLA 890

Query: 948  SSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNP 1007
             +  +        +   F+TT    LLL+ S    +++ + L       I Y  D    P
Sbjct: 891  LATLQ--AYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGP 945

Query: 1008 DAFTFDF-KNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL 1066
                 +  K + D Q H V ++R+   V      S       +     +    L +G + 
Sbjct: 946  SLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLS 1005

Query: 1067 EAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097
            +   ++     A+  GF GCL++V      P
Sbjct: 1006 KNMFSNLPKLVASRDGFQGCLASVDLNGRLP 1036



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 813 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFN 871
           T ++   F+T   +G+ +      D++ + L++   V    ++G+G  E  V+     FN
Sbjct: 287 TDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFN 345

Query: 872 DNQWHHVRAERNVK 885
           DN WH VR  RN++
Sbjct: 346 DNAWHDVRVTRNLR 359



 Score = 38.9 bits (89), Expect = 0.030
 Identities = 45/175 (25%), Positives = 74/175 (42%), Gaps = 21/175 (12%)

Query: 961  ITLSFRTTRSPSLLLYVSSFYE-EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 1019
            ++ S RT  + +LLLY+    + ++L ++L + G L++R+ L   + P     D   +AD
Sbjct: 53   LSFSLRTNATRALLLYLDDGGDCDFLELLLVD-GRLRLRFTLSCAE-PATLQLDTP-VAD 109

Query: 1020 GQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAA 1079
             + H V + R+     + V+  A+   + S   E      L +G      G  PD R +A
Sbjct: 110  DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVG------GIPPDVRLSA 163

Query: 1080 TS--------GFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMAR-CAAG 1125
             +         F G L+ ++ G   P  A L   G    T     AP    CA G
Sbjct: 164  LTLSTVKYEPPFRGLLANLKLGERPP--ALLGSQGLRGATADPLCAPARNPCANG 216



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 48/219 (21%), Positives = 81/219 (36%), Gaps = 23/219 (10%)

Query: 386 NSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAG 445
           +SGE    ++F  RT      LL+ +         L L DG+L+L    +   P  +   
Sbjct: 49  SSGE----LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLD 104

Query: 446 AGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGC 503
             + D +WH V  +       + VD +     + +    +      + GG   +   S  
Sbjct: 105 TPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSAL 164

Query: 504 KSPL----GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY--CE 557
                     F+G L  + +G++    +L  QG  G+  D           C P+   C 
Sbjct: 165 TLSTVKYEPPFRGLLANLKLGERP-PALLGSQGLRGATAD---------PLCAPARNPCA 214

Query: 558 HGGECSQ-SWDTFSCDCLGTGYTGETCHSSLYEQSCEAH 595
           +GG C+  +     CDC  TG+ G+ C    +     AH
Sbjct: 215 NGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAH 253



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 31/146 (21%), Positives = 63/146 (43%), Gaps = 20/146 (13%)

Query: 787 DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI----------- 835
           D +  +  +F +  +++  P +  + T  +   F+TT  +G+ + + G            
Sbjct: 457 DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSS 516

Query: 836 ---TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD 892
               D+  +EL     +    D+G+G  ++   S    ND +W HV  +R+ +  S+ V+
Sbjct: 517 AQRADYFAMEL-LDGHLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDFQRDGRKGSISVN 574

Query: 893 QLPQKMQPAPADGHVR-LQLNSQLFI 917
               +  P  A G    L L S+L++
Sbjct: 575 ---SRSTPFLATGDSEILDLESELYL 597



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 28/88 (31%), Positives = 45/88 (51%), Gaps = 8/88 (9%)

Query: 834  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPF-NDNQWHHVRAERNVKGASLQVD 892
            G+ D++++ +   T V   F+VG    ++T+  P    +D ++H VR  R+   A+LQVD
Sbjct: 1146 GLGDYLQLHIDQGT-VGVIFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202

Query: 893  QLP-QKMQPAPADGHVRLQLNSQLFIEI 919
              P  +  PA   G      NSQ  I+I
Sbjct: 1203 SWPVNERYPA---GRQLTIFNSQAAIKI 1227



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 9/105 (8%)

Query: 241 LVFFLNSGNAKLPSTIA---PVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQA 297
           L   L  G  +L  T++   P TL L + + D  WH VL+     +    VD      + 
Sbjct: 78  LELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEV 137

Query: 298 KGDSSNLDLNFEISFGGILSPGRSRAFTRKS------FHGCLENL 336
           +     + +  ++  GGI    R  A T  +      F G L NL
Sbjct: 138 RSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANL 182


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  117 bits (292), Expect = 9e-26
 Identities = 109/418 (26%), Positives = 179/418 (42%), Gaps = 20/418 (4%)

Query: 177 CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
           C  ++ ++ +DG   +   +         DV S +F + ++ G+L+    +   + + LE
Sbjct: 306 CEREASILSYDGSMYMKIIMPMVMHTEAEDV-SFRFMSQRAYGLLVATTSRDSADTLRLE 364

Query: 236 LIKGKLVFFLNSGNAKLP--STIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTH 293
           L  G++   +N    ++   S+  P TL  G  L+D  WH+V +      +  TVD    
Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424

Query: 294 HFQAKGDSSNLDL-NFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKP 352
                GD + L+  N E    GI++  R  +    SF G L++L +NG+   +L K    
Sbjct: 425 EGTMVGDHTRLEFHNIET---GIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDI 481

Query: 353 QILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGEL 412
               +    F        PVTF +  SYL+L        + + FQF+T +  G +LF   
Sbjct: 482 DYCEL-KARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSG 540

Query: 413 QRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVVD 470
             G+    + L  G +   +F  G  P  +   +   LND QWH+V  +   S+ + +  
Sbjct: 541 D-GNDFIAVELVKGYIHY-VFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKV 598

Query: 471 DDTAVQPLV--AVLID-SGDTYYFGGCLGNSSG-SGCKSPLGGFQGCLRLITIGDKAVDP 526
           D   V  ++  A  +D  GD Y  G   G  S      +   GFQGCL  + +  +  D 
Sbjct: 599 DTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDL 658

Query: 527 ILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
           I     AL     ++    G +  C    C + G C Q W+ F+CDC  T Y+G  C+
Sbjct: 659 I---NDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN 713



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 75/286 (26%), Positives = 121/286 (42%), Gaps = 36/286 (12%)

Query: 328 SFHGCLENLYYNGVDV----TELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLA 382
           +F GCL+ + Y   D+    + LA+    ++ + G V F C    T+ P+ F +  +Y++
Sbjct: 27  NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFETPEAYIS 86

Query: 383 LPGNSGEDKVSVTFQFRTWNRAGHLLF--GELQRGSGS----------FVLFLKDGKLKL 430
           LP  + +   S++F FRT    G +LF  G+ Q    +          F + L DG L L
Sbjct: 87  LPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYL 146

Query: 431 SLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAV----LIDSG 486
            L     + +        NDG+W+ V          + V+      P  A     ++D  
Sbjct: 147 LLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRT--PFTASGESEILDLE 204

Query: 487 DTYYFGGCLGNSSGSGCKSPLG------GFQGCLRLITIG--DKAVDPILVQQGALGSFR 538
              Y GG   N +G    + L       G+ GC+R + I    K +  +   Q A G   
Sbjct: 205 GDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAG--- 261

Query: 539 DLQIDSCGITDRCLPSY-CEHGGECSQSWDTFSCDCLGTGYTGETC 583
            ++     ++ +   SY C++   C   W+ F CDC GTGY G TC
Sbjct: 262 -VKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTC 306



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 44/125 (35%), Positives = 61/125 (48%), Gaps = 6/125 (4%)

Query: 795 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 853
           +F T++SYL         +  + F FKTT   G  + N G   DFI +EL     + + F
Sbjct: 501 TFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVEL-VKGYIHYVF 559

Query: 854 DVGNGPCEVTVQSPTPFNDNQWHHVRAER-NVKGASLQVDQLPQKMQPAPADGHVRLQLN 912
           D+GNGP  +   S  P NDNQWH+V   R N    SL+VD    K+     +G   L L 
Sbjct: 560 DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVD---TKVVTQVINGAKNLDLK 616

Query: 913 SQLFI 917
             L++
Sbjct: 617 GDLYM 621



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 71/340 (20%), Positives = 123/340 (36%), Gaps = 76/340 (22%)

Query: 208 ISLKFKAMQSNGILLHREGQHGNH-------------ITLELIKGKLVFFLN--SGNAKL 252
           IS  F+  + NG++L   G+                   +EL+ G L   L+  SG  K+
Sbjct: 98  ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKV 157

Query: 253 PSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISF 312
            +T            +D  W+ V I+        +V+     F A G+S  LDL  ++  
Sbjct: 158 KATQKKA--------NDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYL 209

Query: 313 GG--------ILSPGRSRAFTRKSFHGCLENLYYNG--VDVTELAKKHKPQILMMGNVSF 362
           GG        IL      A     + GC+ +L+ +G   ++ +LA+      +       
Sbjct: 210 GGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRM 269

Query: 363 SCPQPQTVPV-----------TFLSSRSYLALPGNSGEDKVS------------------ 393
           S  Q  + P             F+   +     G + E + S                  
Sbjct: 270 SAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVM 329

Query: 394 ------VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL--------FQAGQSP 439
                 V+F+F +    G L+    +  + +  L L  G++KL +          + + P
Sbjct: 330 HTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGP 389

Query: 440 RNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLV 479
             + AG  LND +WH+V    +   + + VDDD A   +V
Sbjct: 390 ETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMV 429



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 75/309 (24%), Positives = 113/309 (36%), Gaps = 68/309 (22%)

Query: 863  TVQSPTPFNDNQWHHVRAERNVKGASLQVDQ-----------------------LPQK-- 897
            T+ +    NDN+WH VR  R  K   L VD                        + +K  
Sbjct: 391  TLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRY 450

Query: 898  --MQPAPADGHVR-LQLNSQLFI-----------EISAYFATGSSMTYHFQEHYTLSENS 943
              + P+   GH++ L  N  L+I           E+ A F   + +     +  T    S
Sbjct: 451  ISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIA----DPVTFKTKS 506

Query: 944  SSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDR 1003
            S L  SL      T   +   F+TT     +L+ S    ++++V L       I Y  D 
Sbjct: 507  SYL--SLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKG---YIHYVFDL 561

Query: 1004 HQNPDAFTFDF-KNMADGQLHQVKINREEAVV-MVEVNQSAKKQVILSSGTEFNAVKSLI 1061
               P+    +  + + D Q H V I R+ +    ++V+     QVI       N  K+L 
Sbjct: 562  GNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVI-------NGAKNLD 614

Query: 1062 LGKVLEAAG------ADPDTRRAATSGFTGCLSAVRFGRAAP--LKAALRPSGPSRVTVR 1113
            L   L  AG      ++     A+  GF GCL++V      P  +  AL  SG      R
Sbjct: 615  LKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIE---R 671

Query: 1114 GHVAPMARC 1122
            G   P   C
Sbjct: 672  GCEGPSTTC 680



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 25/79 (31%), Positives = 41/79 (51%), Gaps = 5/79 (6%)

Query: 820 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 876
           F TTV  G+ +      G+ DF+++ +    ++   F++G     +  +  TP ND ++H
Sbjct: 749 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 806

Query: 877 HVRAERNVKGASLQVDQLP 895
            VR  RN   A+LQVD  P
Sbjct: 807 VVRFTRNGGNATLQVDNWP 825



 Score = 38.1 bits (87), Expect = 0.051
 Identities = 30/138 (21%), Positives = 59/138 (42%), Gaps = 20/138 (14%)

Query: 795 SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLG--------------ITDFIR 840
           +F T  +Y+  P ++ +    + F F+TT  +G+ +   G                DF  
Sbjct: 77  NFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFA 136

Query: 841 IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 900
           +EL     +    D+G+G  +V   +    ND +W+HV  +R+ +  ++ V+    +  P
Sbjct: 137 VEL-LDGNLYLLLDMGSGTIKVKA-TQKKANDGEWYHVDIQRDGRSGTISVN---SRRTP 191

Query: 901 APADGHVR-LQLNSQLFI 917
             A G    L L   +++
Sbjct: 192 FTASGESEILDLEGDMYL 209



 Score = 35.4 bits (80), Expect = 0.33
 Identities = 47/202 (23%), Positives = 80/202 (39%), Gaps = 25/202 (12%)

Query: 185 YFDGQSA--LLYTLDKKPLKPIR-DVISLKFKAMQSNGILLHREGQHG--NHITLELIKG 239
           Y  G+S   +LYT         R D +++ F     +GIL+  +   G  + + L + +G
Sbjct: 719 YIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQG 778

Query: 240 KL--VFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKH--THHF 295
           K+  VF + + +  +     PV        +D  +H V            VD      H+
Sbjct: 779 KIGVVFNIGTVDISIKEERTPV--------NDGKYHVVRFTRNGGNATLQVDNWPVNEHY 830

Query: 296 QAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQIL 355
                 +  +   +I+ GG    GR        F G L  LYY+G+ V  +A ++ P I 
Sbjct: 831 PTGRQLTIFNTQAQIAIGG-KDKGRL-------FQGQLSGLYYDGLKVLNMAAENNPNIK 882

Query: 356 MMGNVSFSCPQPQTVPVTFLSS 377
           + G+V      P  +  T  +S
Sbjct: 883 INGSVRLVGEVPSILGTTQTTS 904


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 54/160 (33%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 31  CDSPLA---SALPRSSFSSSSELSS------SHGPGFSRLNRRDGAGGWTPLVSNKYQWL 81
           C +PL    +++P    ++SS   +      S  P ++RL+++     W        QWL
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289

Query: 82  QIDLGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYR--REESIWGFPGNTN 137
           Q+DLG   EVT + TQG   +GS  +V SY + +S+   NW +Y+  R  S   FPGN +
Sbjct: 290 QVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWD 349

Query: 138 ADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             S      + P  AR++R LP+AW+   RI +R+E+ GC
Sbjct: 350 NHSHKKNLFETPILARYVRILPVAWH--NRIALRLELLGC 387



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 17  TQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVS 75
           T+   P+G  N    +S +A++  R +F     L   H  P  +RLNR      WTP  +
Sbjct: 68  TKCVEPLGLENGNIANSQIAASSVRVTF-----LGLQHWVPELARLNRAGMVNAWTPSSN 122

Query: 76  NKYQWLQIDLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNW-------KQYRRE 126
           +   W+Q++L  RM VT V TQG     S +++ ++ + +S  G  +       K+++  
Sbjct: 123 DDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKE- 181

Query: 127 ESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
                F GN N ++V     + P EA+++R  P + +      +R E+ GC
Sbjct: 182 -----FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT--ACTLRFELLGC 225


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 54/158 (34%), Positives = 79/158 (50%), Gaps = 13/158 (8%)

Query: 31   CDSPLA---SALPRSSFSSSSELSSSHG----PGFSRLNRRDGAGGWTPLVSNKYQWLQI 83
            C +PL      +     ++SS   S  G    P  +RLN +     W    +N  QWL+I
Sbjct: 2066 CSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEI 2125

Query: 84   DLGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWG--FPGNTNAD 139
            DL +  ++TA+ TQG     S  +V SY + +S+ G  WK YR + S+    F GNTN  
Sbjct: 2126 DLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTK 2185

Query: 140  SVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
              V     PP  +RF+R +P  WN    I +R+E++GC
Sbjct: 2186 GHVKNFFNPPIISRFIRVIPKTWNQ--SIALRLELFGC 2221



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 14/159 (8%)

Query: 30   DCDSP--LASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWT--PLVSN--KYQWLQI 83
            DC  P  L++ +   S   +SE      P  +RLN       W+   L +      W+Q+
Sbjct: 1906 DCRMPMGLSTGIISDSQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQV 1965

Query: 84   DLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNWKQYRREES--IWGFPGNTNAD 139
            D+ + + +T + TQG   Y  S + T + + +S    NW+ ++   +  +  F GN++A 
Sbjct: 1966 DMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDAS 2025

Query: 140  SVVHYRLQPPFEARFLRFLPL-AWNPRGRIGMRIEVYGC 177
            ++   +  PP  AR++R  P  A+N   R  +R+E+ GC
Sbjct: 2026 TIKENQFDPPIVARYIRISPTRAYN---RPTLRLELQGC 2061


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 12/199 (6%)

Query: 8   VLKVLLLLPTQTWSPVGAGNPPDCDSPLASA---LPRSSFSSSSELSSSHGPGFSRLNRR 64
           +L + LLLP  + S     NP  C  PL  +   +P    ++SS+ S S    + RL+  
Sbjct: 8   LLVLFLLLPILS-SAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSE 66

Query: 65  DGAGGWTPLV----SNKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLLMFSDGG 117
           +G G W P +     +  ++LQIDL     +T V TQG +      ++   Y + +S  G
Sbjct: 67  EGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG 126

Query: 118 RNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             W  +R         GN+N   +    L+PP  ARF+RF+P+  +    + MR+E+YGC
Sbjct: 127 TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVT-DHSMNVCMRVELYGC 185

Query: 178 AYKSEVVYFDGQSALLYTL 196
            +   +V ++  +   + L
Sbjct: 186 VWLDGLVSYNAPAGQQFVL 204


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 12/199 (6%)

Query: 8   VLKVLLLLPTQTWSPVGAGNPPDCDSPLASA---LPRSSFSSSSELSSSHGPGFSRLNRR 64
           +L + LLLP  + S     NP  C  PL  +   +P    ++SS+ S S    + RL+  
Sbjct: 8   LLVLFLLLPILS-SAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSE 66

Query: 65  DGAGGWTPLV----SNKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLLMFSDGG 117
           +G G W P +     +  ++LQIDL     +T V TQG +      ++   Y + +S  G
Sbjct: 67  EGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG 126

Query: 118 RNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             W  +R         GN+N   +    L+PP  ARF+RF+P+  +    + MR+E+YGC
Sbjct: 127 TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVT-DHSMNVCMRVELYGC 185

Query: 178 AYKSEVVYFDGQSALLYTL 196
            +   +V ++  +   + L
Sbjct: 186 VWLDGLVSYNAPAGQQFVL 204


>gi|38327632 discoidin domain receptor family, member 1 isoform b
           [Homo sapiens]
          Length = 876

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 16/198 (8%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLAS---ALPRSSFSSSSELSSSHGPG 57
           M   A + L +LLL+ +      G  +P  C   L      +P S  S+SS  S S    
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 58  FSRLNRRDGAGGWTPLVS---NKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLL 111
            SRL   DG G W P  S    + ++LQ+DL     V  V TQG +      ++  SY L
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 112 MFSDGGRNWKQYRREESIWG---FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRI 168
            +S  GR W  ++     WG     GN + + VV   L PP  AR +RF P A      +
Sbjct: 121 RYSRDGRRWMGWKDR---WGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMS-V 176

Query: 169 GMRIEVYGCAYKSEVVYF 186
            +R+E+YGC ++  ++ +
Sbjct: 177 CLRVELYGCLWRDGLLSY 194


>gi|83977452 discoidin domain receptor family, member 1 isoform c
           [Homo sapiens]
          Length = 919

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 16/198 (8%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLAS---ALPRSSFSSSSELSSSHGPG 57
           M   A + L +LLL+ +      G  +P  C   L      +P S  S+SS  S S    
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 58  FSRLNRRDGAGGWTPLVS---NKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLL 111
            SRL   DG G W P  S    + ++LQ+DL     V  V TQG +      ++  SY L
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 112 MFSDGGRNWKQYRREESIWG---FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRI 168
            +S  GR W  ++     WG     GN + + VV   L PP  AR +RF P A      +
Sbjct: 121 RYSRDGRRWMGWKDR---WGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMS-V 176

Query: 169 GMRIEVYGCAYKSEVVYF 186
            +R+E+YGC ++  ++ +
Sbjct: 177 CLRVELYGCLWRDGLLSY 194


>gi|83977450 discoidin domain receptor family, member 1 isoform a
           [Homo sapiens]
          Length = 913

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 16/198 (8%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLAS---ALPRSSFSSSSELSSSHGPG 57
           M   A + L +LLL+ +      G  +P  C   L      +P S  S+SS  S S    
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 58  FSRLNRRDGAGGWTPLVS---NKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLL 111
            SRL   DG G W P  S    + ++LQ+DL     V  V TQG +      ++  SY L
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 112 MFSDGGRNWKQYRREESIWG---FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRI 168
            +S  GR W  ++     WG     GN + + VV   L PP  AR +RF P A      +
Sbjct: 121 RYSRDGRRWMGWKDR---WGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMS-V 176

Query: 169 GMRIEVYGCAYKSEVVYF 186
            +R+E+YGC ++  ++ +
Sbjct: 177 CLRVELYGCLWRDGLLSY 194


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 61/227 (26%), Positives = 96/227 (42%), Gaps = 14/227 (6%)

Query: 364  CPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFL 423
            C +    PV     RS+LA P       + +  +FR     G LL+    RG     L L
Sbjct: 1366 CEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALAL 1425

Query: 424  KDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVA 480
             DG+++L  F  G  P  +T+   +  GQWH +  S  W    + VD +T V    P   
Sbjct: 1426 LDGRVQLR-FDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGT 1484

Query: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPL--GGFQGCLRLITIGDKAVDPILVQQGALGSFR 538
              ++     + GG   + +    +      G +GC+RL+ + ++ ++   +  G   + R
Sbjct: 1485 DGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLE---LGIGPGAATR 1541

Query: 539  DLQIDSCGITDRCLPSYCEHGGECSQSWDT--FSCDCLGTGYTGETC 583
               +  CG    CLP+ C HGG   Q+ +   F C C   G  G TC
Sbjct: 1542 GSGVGECG-DHPCLPNPC-HGGAPCQNLEAGRFHCQC-PPGRVGPTC 1585



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 49/209 (23%), Positives = 87/209 (41%), Gaps = 15/209 (7%)

Query: 390  DKVSVTFQFRTWNRAGHLLF-GELQRGSGSFV-LFLKDGKLKLSLFQAGQSPRNVTAGAG 447
            +K+++   F     +G LL+ G+   G G FV L L+D +L+   +  G+    + +   
Sbjct: 1660 EKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFR-YDLGKGAAVIRSREP 1718

Query: 448  LNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVAVLIDSGDTYYFGGCLGNSSGSGCK 504
            +  G W  VS         + V D   V    P+   +++  +  Y GG    S  +   
Sbjct: 1719 VTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAA 1778

Query: 505  SPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG--ITDRCLPSYCEHGGEC 562
            +   GF G ++L+++G +    +L  +  L   R + + S       R     C +G  C
Sbjct: 1779 AVSSGFDGAIQLVSLGGR---QLLTPEHVL---RQVDVTSFAGHPCTRASGHPCLNGASC 1832

Query: 563  SQSWDTFSCDCLGTGYTGETCHSSLYEQS 591
                  + C C G G++G  C   L E+S
Sbjct: 1833 VPREAAYVCLCPG-GFSGPHCEKGLVEKS 1860



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 29/138 (21%), Positives = 61/138 (44%), Gaps = 13/138 (9%)

Query: 208  ISLKFKAMQSNGILLHREGQHG-NHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSL 266
            ++L+F+A++  G+LL+     G + + L L+ G++    ++G+        P  LT    
Sbjct: 1396 LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGS-------GPAVLTSAVP 1448

Query: 267  LDDQHWHSVLIELLDTQVNFTVDKHTHHF-QAKGDSSNLDLNFEISFGGI----LSPGRS 321
            ++   WH + +     +   +VD  T    ++   +  L+L+ ++  GG+     +    
Sbjct: 1449 VEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALE 1508

Query: 322  RAFTRKSFHGCLENLYYN 339
            R F      GC+  L  N
Sbjct: 1509 RTFVGAGLRGCIRLLDVN 1526



 Score = 30.8 bits (68), Expect = 8.1
 Identities = 16/40 (40%), Positives = 24/40 (60%), Gaps = 2/40 (5%)

Query: 852  SFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQV 891
            S+++G+ P  V ++S  P N N+W  V A R  +  SLQV
Sbjct: 1931 SYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQV 1968


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 11/150 (7%)

Query: 46  SSSELSSSHGPGFSRLNRRDGA-------GGWTPLVSNKYQWLQIDLGERMEVTAVATQG 98
           +SS L    G    RLN + GA       G W      + QW+++D       T V TQG
Sbjct: 402 ASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQG 461

Query: 99  GYGS--SDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLR 156
              S   D+VT++ + FS+  + W  Y        F GN + D+ V   L  P  ARF+R
Sbjct: 462 RDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIR 521

Query: 157 FLPLAWNPRGRIGMRIEVYGCAYKSEVVYF 186
             PL WN  G + MR+EV GC+      Y+
Sbjct: 522 IYPLTWN--GSLCMRLEVLGCSVAPVYSYY 549


>gi|10518506 coagulation factor VIII isoform b precursor [Homo
           sapiens]
          Length = 216

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 10/155 (6%)

Query: 31  CDSPL---ASALPRSSFSSSS---ELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQID 84
           C  PL   + A+  +  ++SS    + ++  P  +RL+ +  +  W P V+N  +WLQ+D
Sbjct: 58  CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117

Query: 85  LGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142
             + M+VT V TQG     +S +V  +L+  S  G  W  + +   +  F GN ++ + V
Sbjct: 118 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 177

Query: 143 HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
              L PP   R+LR  P +W    +I +R+EV GC
Sbjct: 178 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 210



 Score = 32.0 bits (71), Expect = 3.7
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 132 FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKS 181
           F GN ++  + H    PP  AR++R  P  ++ R    +R+E+ GC   S
Sbjct: 10  FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRST--LRMELMGCDLNS 57


>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
          Length = 2351

 Score = 77.4 bits (189), Expect = 8e-14
 Identities = 48/155 (30%), Positives = 80/155 (51%), Gaps = 10/155 (6%)

Query: 31   CDSPL---ASALPRSSFSSSS---ELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQID 84
            C  PL   + A+  +  ++SS    + ++  P  +RL+ +  +  W P V+N  +WLQ+D
Sbjct: 2193 CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 2252

Query: 85   LGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142
              + M+VT V TQG     +S +V  +L+  S  G  W  + +   +  F GN ++ + V
Sbjct: 2253 FQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPV 2312

Query: 143  HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
               L PP   R+LR  P +W    +I +R+EV GC
Sbjct: 2313 VNSLDPPLLTRYLRIHPQSW--VHQIALRMEVLGC 2345



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 10/157 (6%)

Query: 31   CDSPL--ASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGER 88
            C +PL  AS   R    ++S       P  +RL+       W+      + W+++DL   
Sbjct: 2040 CQTPLGMASGHIRDFQITASGQYGQWAPKLARLHYSGSINAWS--TKEPFSWIKVDLLAP 2097

Query: 89   MEVTAVATQGGYG--SSDWVTSYLLMFSDGGRNWKQYRREES--IWGFPGNTNADSVVHY 144
            M +  + TQG     SS +++ +++M+S  G+ W+ YR   +  +  F GN ++  + H 
Sbjct: 2098 MIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNVDSSGIKHN 2157

Query: 145  RLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKS 181
               PP  AR++R  P  ++ R    +R+E+ GC   S
Sbjct: 2158 IFNPPIIARYIRLHPTHYSIRST--LRMELMGCDLNS 2192


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 52/155 (33%), Positives = 76/155 (49%), Gaps = 12/155 (7%)

Query: 31  CDSPL---ASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVSNKYQWLQIDLG 86
           C+ PL   +  +     S+SS  S     P  SRL+  D   GWTP + +  ++LQ+DL 
Sbjct: 277 CNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDN--GWTPNLDSNKEYLQVDLR 334

Query: 87  ERMEVTAVATQGGYGSSD----WVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVV 142
               +TA+ATQG          +V SY L  S  G +W  YR  ++   F  N +A  VV
Sbjct: 335 FLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVV 394

Query: 143 HYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             +L  P   RF+R  P  W+    I +R+E++GC
Sbjct: 395 LNKLHAPLLTRFVRIRPQTWH--SGIALRLELFGC 427



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 48/156 (30%), Positives = 70/156 (44%), Gaps = 17/156 (10%)

Query: 35  LASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKY---QWLQIDLGERMEV 91
           L+  +  S  S+SS       P  +RL       GW P +       +WLQ+DLG    V
Sbjct: 441 LSGLIADSQISASSTQEYLWSPSAARLV--SSRSGWFPRIPQAQPGEEWLQVDLGTPKTV 498

Query: 92  TAVATQGGYGSSD--------WVTSYLLMFSDGGRNWK--QYRREESIWGFPGNTNADSV 141
             V  QG  G           +V  + + +S  G++W+  Q  R +    F GN + D+ 
Sbjct: 499 KGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDT- 557

Query: 142 VHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
              R   P  A+++R  P  W+P G IGMR+EV GC
Sbjct: 558 PDIRRFDPIPAQYVRVYPERWSPAG-IGMRLEVLGC 592


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,941,617
Number of Sequences: 37866
Number of extensions: 2392718
Number of successful extensions: 7679
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 6693
Number of HSP's gapped (non-prelim): 795
length of query: 1207
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1093
effective length of database: 13,930,794
effective search space: 15226357842
effective search space used: 15226357842
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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