Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 239743754

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform
1 [Homo sapiens]
         (1288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1...  2639   0.0  
gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]          2597   0.0  
gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2...  1903   0.0  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...  1845   0.0  
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...  1722   0.0  
gi|18640734 contactin associated protein-like 5 [Homo sapiens]       1399   0.0  
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi...  1209   0.0  
gi|239743797 PREDICTED: similar to cell recognition molecule CAS...  1201   0.0  
gi|4505463 contactin associated protein 1 precursor [Homo sapiens]    884   0.0  
gi|239743729 PREDICTED: similar to contactin associated protein-...   723   0.0  
gi|169184330 PREDICTED: novel protein similar to contactin assoc...   550   e-156
gi|239758135 PREDICTED: similar to cell recognition molecule CAS...   265   2e-70
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]        216   1e-55
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]       214   4e-55
gi|239752499 PREDICTED: similar to cell recognition molecule Cas...   146   1e-34
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]       135   2e-31
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]       135   3e-31
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]             117   9e-26
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho...    90   1e-17
gi|105990535 coagulation factor V precursor [Homo sapiens]             86   2e-16
gi|62420886 discoidin domain receptor family, member 2 precursor...    84   7e-16
gi|62420884 discoidin domain receptor family, member 2 precursor...    84   7e-16
gi|38327632 discoidin domain receptor family, member 1 isoform b...    79   3e-14
gi|83977452 discoidin domain receptor family, member 1 isoform c...    79   3e-14
gi|83977450 discoidin domain receptor family, member 1 isoform a...    79   3e-14
gi|33469931 EGF-like, fibronectin type III and laminin G domains...    79   4e-14
gi|33469929 EGF-like, fibronectin type III and laminin G domains...    79   4e-14
gi|33469935 EGF-like, fibronectin type III and laminin G domains...    78   5e-14
gi|54873613 agrin [Homo sapiens]                                       78   6e-14
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo...    78   6e-14

>gi|239743754 PREDICTED: hypothetical protein LOC389722 isoform 1
            [Homo sapiens]
          Length = 1288

 Score = 2639 bits (6841), Expect = 0.0
 Identities = 1288/1288 (100%), Positives = 1288/1288 (100%)

Query: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
            MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
            LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
            KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
            SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK
Sbjct: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
            LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD
Sbjct: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
            SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV
Sbjct: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
            SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV
Sbjct: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420

Query: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480
            LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA
Sbjct: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480

Query: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
            VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL
Sbjct: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540

Query: 541  QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600
            QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN
Sbjct: 541  QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600

Query: 601  PSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 660
            PSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA
Sbjct: 601  PSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 660

Query: 661  AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720
            AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ
Sbjct: 661  AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720

Query: 721  KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 780
            KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL
Sbjct: 721  KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 780

Query: 781  GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840
            GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI
Sbjct: 781  GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840

Query: 841  RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900
            RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ
Sbjct: 841  RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900

Query: 901  PAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAG 960
            PAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAG
Sbjct: 901  PAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAG 960

Query: 961  HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTL 1020
            HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTL
Sbjct: 961  HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTL 1020

Query: 1021 SENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRY 1080
            SENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRY
Sbjct: 1021 SENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRY 1080

Query: 1081 KLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKS 1140
            KLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKS
Sbjct: 1081 KLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKS 1140

Query: 1141 LILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPM 1200
            LILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPM
Sbjct: 1141 LILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPM 1200

Query: 1201 ARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLC 1260
            ARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLC
Sbjct: 1201 ARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLC 1260

Query: 1261 ITAIAIRIYQQRKLRKENESKVSKKEEC 1288
            ITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 1261 ITAIAIRIYQQRKLRKENESKVSKKEEC 1288


>gi|47519929 cell recognition molecule CASPR3 [Homo sapiens]
          Length = 1288

 Score = 2597 bits (6731), Expect = 0.0
 Identities = 1265/1288 (98%), Positives = 1277/1288 (99%)

Query: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
            MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCD+PLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
            LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
            KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
            SEVVYFDGQSALLY LDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK
Sbjct: 181  SEVVYFDGQSALLYRLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
            LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD
Sbjct: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
            SS LDLNFEISFGGI +PGRSRAF RKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV
Sbjct: 301  SSYLDLNFEISFGGIPTPGRSRAFRRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
            SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGEL+RGSGSFV
Sbjct: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFV 420

Query: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480
            LFLKDGKLKLSLFQ GQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA
Sbjct: 421  LFLKDGKLKLSLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480

Query: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
            VLIDSGDTYYFGGCL NSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL
Sbjct: 481  VLIDSGDTYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540

Query: 541  QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600
            QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN
Sbjct: 541  QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600

Query: 601  PSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 660
            PSGLYYIDADGSGPLGPFLVYCNMTAD+AWTVV+HGGPDAVTLRGAPSGHP SAVSFAYA
Sbjct: 601  PSGLYYIDADGSGPLGPFLVYCNMTADAAWTVVQHGGPDAVTLRGAPSGHPRSAVSFAYA 660

Query: 661  AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720
            AGAGQLR+AVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ
Sbjct: 661  AGAGQLRSAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720

Query: 721  KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 780
            KCTCGLEGNCIDSQYYCNCDAG+NEWTSDTIVLSQKEHLPVTQIVMTD G+PHSEA YTL
Sbjct: 721  KCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVLSQKEHLPVTQIVMTDAGRPHSEAAYTL 780

Query: 781  GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840
            GPLLCRGD+SFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI
Sbjct: 781  GPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840

Query: 841  RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900
            RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ
Sbjct: 841  RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900

Query: 901  PAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAG 960
            PAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAG
Sbjct: 901  PAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAG 960

Query: 961  HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTL 1020
            HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTL
Sbjct: 961  HCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTL 1020

Query: 1021 SENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRY 1080
            SENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYVSSFYEEYLSVILANNGSLQIRY
Sbjct: 1021 SENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVILANNGSLQIRY 1080

Query: 1081 KLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKS 1140
            KLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQS KKQVILSSGTEFNAVKS
Sbjct: 1081 KLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSTKKQVILSSGTEFNAVKS 1140

Query: 1141 LILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPM 1200
            LILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPM
Sbjct: 1141 LILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPM 1200

Query: 1201 ARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLC 1260
            ARCAAGAASGSPARELAPRLAGGAGRSGP DEGEPLVNADRRDSAV+GGVIAVVIFILLC
Sbjct: 1201 ARCAAGAASGSPARELAPRLAGGAGRSGPADEGEPLVNADRRDSAVIGGVIAVVIFILLC 1260

Query: 1261 ITAIAIRIYQQRKLRKENESKVSKKEEC 1288
            ITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 1261 ITAIAIRIYQQRKLRKENESKVSKKEEC 1288


>gi|239743756 PREDICTED: hypothetical protein LOC389722 isoform 2
           [Homo sapiens]
          Length = 1207

 Score = 1903 bits (4930), Expect = 0.0
 Identities = 917/918 (99%), Positives = 917/918 (99%), Gaps = 1/918 (0%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
           MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
           LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
           KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
           SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK
Sbjct: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240

Query: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
           LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300

Query: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
           SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV
Sbjct: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360

Query: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
           SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV
Sbjct: 361 SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420

Query: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480
           LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA
Sbjct: 421 LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVA 480

Query: 481 VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540
           VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL
Sbjct: 481 VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDL 540

Query: 541 QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600
           QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN
Sbjct: 541 QIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGN 600

Query: 601 PSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 660
           PSGLYYIDADGSGPLGPFLVYCNMT DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA
Sbjct: 601 PSGLYYIDADGSGPLGPFLVYCNMT-DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYA 659

Query: 661 AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 720
           AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ
Sbjct: 660 AGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQ 719

Query: 721 KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 780
           KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL
Sbjct: 720 KCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTL 779

Query: 781 GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 840
           GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI
Sbjct: 780 GPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFI 839

Query: 841 RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 900
           RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ
Sbjct: 840 RIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQ 899

Query: 901 PAPADGHVRLQLNSQLFI 918
           PAPADGHVRLQLNSQLFI
Sbjct: 900 PAPADGHVRLQLNSQLFI 917



 Score =  561 bits (1446), Expect = e-159
 Identities = 290/290 (100%), Positives = 290/290 (100%)

Query: 999  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 1058
            EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV
Sbjct: 918  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 977

Query: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1118
            SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 978  SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1037

Query: 1119 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1178
            VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP
Sbjct: 1038 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1097

Query: 1179 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1238
            LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN
Sbjct: 1098 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1157

Query: 1239 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1288
            ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 1158 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1207



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)

Query: 757  EHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 816
            E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 334  ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393

Query: 817  VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 873
            V F F+T   +G  +F E   G   F+        +++  F  G  P  VT  +    ND
Sbjct: 394  VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVTAGAG--LND 450

Query: 874  NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG------ 927
             QWH V         ++ VD     +QP  A   V +      + GG      G      
Sbjct: 451  GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506

Query: 928  ---FLGCIRSLQLNGVALD--LEERATVTPGVE---PGCAGHCSTYGHLCRNGGRCREKR 979
               F GC+R + +   A+D  L ++  +    +     C          C +GG C +  
Sbjct: 507  LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566

Query: 980  RGVTCDCAFSAYDGPFCSNEI 1000
               +CDC  + Y G  C + +
Sbjct: 567  DTFSCDCLGTGYTGETCHSSL 587



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 821 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 874
           FK   S+G+ +   G   + I +EL    ++ F  + GN     T+   T       +D 
Sbjct: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 875 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 927
            WH V  E      +  VD+     Q A  D    L LN ++  GG        A  ++ 
Sbjct: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328

Query: 928 FLGCIRSLQLNGV 940
           F GC+ +L  NGV
Sbjct: 329 FHGCLENLYYNGV 341


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sapiens]
          Length = 1308

 Score = 1845 bits (4779), Expect = 0.0
 Identities = 898/1286 (69%), Positives = 1048/1286 (81%), Gaps = 8/1286 (0%)

Query: 1    MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
            M SV  AVLK LLLL TQ W+ V AGN  DCD PL SALP++SFSSSSELSSSHGPGF+R
Sbjct: 1    MGSVTGAVLKTLLLLSTQNWNRVEAGNSYDCDDPLVSALPQASFSSSSELSSSHGPGFAR 60

Query: 61   LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
            LNRRDGAGGW+PLVSNKYQWLQIDLGERMEVTAVATQGGYGSS+WVTSYLLMFSD G NW
Sbjct: 61   LNRRDGAGGWSPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSNWVTSYLLMFSDSGWNW 120

Query: 121  KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
            KQYR+E+SIWGF GN NADSVV+YRLQP  +ARFLRF+PL WNP+GRIGMRIEV+GCAY+
Sbjct: 121  KQYRQEDSIWGFSGNANADSVVYYRLQPSIKARFLRFIPLEWNPKGRIGMRIEVFGCAYR 180

Query: 181  SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
            SEVV  DG+S+LLY  D+K L PI+D+ISLKFK MQS+GILLHREG +G+HITL+L + +
Sbjct: 181  SEVVDLDGKSSLLYRFDQKSLSPIKDIISLKFKTMQSDGILLHREGPNGDHITLQLRRAR 240

Query: 241  LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
            L   +NSG AKLPST   V LTLGSLLDDQHWHSVLI+ L  QVNFTVD+H HHF A+G+
Sbjct: 241  LFLLINSGEAKLPSTSTLVNLTLGSLLDDQHWHSVLIQRLGKQVNFTVDEHRHHFHARGE 300

Query: 301  SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNV 360
             + ++L++EISFGGI +PG+S +F  ++FHGCLENLYYNGVD+ +LAK+ KPQI+ MGNV
Sbjct: 301  FNLMNLDYEISFGGIPAPGKSVSFPHRNFHGCLENLYYNGVDIIDLAKQQKPQIIAMGNV 360

Query: 361  SFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFV 420
            SFSC QPQ++PVTFLSSRSYLALP  SGE++VS TFQFRTWN+AG LLF ELQ  SG  +
Sbjct: 361  SFSCSQPQSMPVTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGIL 420

Query: 421  LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA-VQPLV 479
            LFL DGKLK +L+Q G+ P ++TAG  LNDGQWHSVS SAK +H++V VD   A   PL+
Sbjct: 421  LFLSDGKLKSNLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLL 480

Query: 480  AV-LIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFR 538
                I SG TYYFGGC   S GS CKSPLGGFQGC+RLI+I  K VD I VQQG+LG+F 
Sbjct: 481  GPEQIYSGGTYYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFS 540

Query: 539  DLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHR 598
            DLQIDSCGI+DRCLP+YCEHGGECSQSW TF C+C  TGY G TCH+S+YEQSCEA+KHR
Sbjct: 541  DLQIDSCGISDRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSIYEQSCEAYKHR 600

Query: 599  GNPSGLYYIDADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFA 658
            GN SG YYID+DGSGPL PFL+YCNMT ++AWT+++H G D   +R     +P +   F 
Sbjct: 601  GNTSGFYYIDSDGSGPLEPFLLYCNMT-ETAWTIIQHNGSDLTRVRNTNPENPYAGF-FE 658

Query: 659  YAAGAGQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPD 718
            Y A   QL+A +N AE CEQ     C  +R  + +DGTPLSWWVGRTNET T WGGS PD
Sbjct: 659  YVASMEQLQATINRAEHCEQEFTYYCKKSRLVNKQDGTPLSWWVGRTNETQTYWGGSSPD 718

Query: 719  AQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADY 778
             QKCTCGLEGNCIDSQYYCNCDA +NEWT+DT +L+ KEHLPVT+IV+TDTG+ HSEA Y
Sbjct: 719  LQKCTCGLEGNCIDSQYYCNCDADRNEWTNDTGLLAYKEHLPVTKIVITDTGRLHSEAAY 778

Query: 779  TLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITD 838
             LGPLLC+GD+SFWNSASF+TE SYLHFP FHGEL+ADV FFFKTT SSGVF+ENLGI D
Sbjct: 779  KLGPLLCQGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLGIAD 838

Query: 839  FIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQK 898
            FIRIELR+PT VTFSFDVGNGP E++VQSPT FNDNQWHHVR ERN+K ASLQVDQL  K
Sbjct: 839  FIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPK 898

Query: 899  MQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGC 958
             QPAPADGHV LQLNSQLF+GGTATRQRGFLGCIRSLQLNG+ LDLEERA VTP V+PGC
Sbjct: 899  TQPAPADGHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPGC 958

Query: 959  AGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHY 1018
             GHCS+YG LCRNGG+CRE+  G  CDC FSAY GPFCSNEISAYF +GSS+ Y+FQE+Y
Sbjct: 959  RGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQENY 1018

Query: 1019 TLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQI 1078
             LS+NSSS  +S + D+ L+REMI  SFRTTR+PSLLL+VSSFY+EYLSVI+A NGSLQI
Sbjct: 1019 LLSKNSSSHAASFHGDMKLSREMIKFSFRTTRTPSLLLFVSSFYKEYLSVIIAKNGSLQI 1078

Query: 1079 RYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAV 1138
            RYKL+++Q PD   FDFKNMADGQLH + INREE VV +E++ + ++QV LSSGTEF+AV
Sbjct: 1079 RYKLNKYQEPDVVNFDFKNMADGQLHHIMINREEGVVFIEIDDNRRRQVHLSSGTEFSAV 1138

Query: 1139 KSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVA 1198
            KSL+LG++LE +  D DT  A   GFTGCLSAV+    APLKAAL PS P  VTV GHV 
Sbjct: 1139 KSLVLGRILEHSDVDQDTALAGAQGFTGCLSAVQLSHVAPLKAALHPSHPDPVTVTGHVT 1198

Query: 1199 PMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFIL 1258
              + C A   + + +RE   R    A  SG +D+ EPL NA + DSAV+GG+IAVVIFIL
Sbjct: 1199 E-SSCMAQPGTDATSRE---RTHSFADHSGTIDDREPLANAIKSDSAVIGGLIAVVIFIL 1254

Query: 1259 LCITAIAIRIYQQRKLRKENESKVSK 1284
            LCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1255 LCITAIAVRIYQQKRLYKRSEAKRSE 1280


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sapiens]
          Length = 1235

 Score = 1722 bits (4461), Expect = 0.0
 Identities = 848/1257 (67%), Positives = 988/1257 (78%), Gaps = 56/1257 (4%)

Query: 30   DCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERM 89
            DCD PL SALP++SFSSSSELSSSHGPGF+RLNRRDGAGGW+PLVSNKYQWLQIDLGERM
Sbjct: 5    DCDDPLVSALPQASFSSSSELSSSHGPGFARLNRRDGAGGWSPLVSNKYQWLQIDLGERM 64

Query: 90   EVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPP 149
            EVTAVATQGGYGSS+WVTSYLLMFSD G NWKQYR+E+SIWGF GN NADSVV+YRLQP 
Sbjct: 65   EVTAVATQGGYGSSNWVTSYLLMFSDSGWNWKQYRQEDSIWGFSGNANADSVVYYRLQPS 124

Query: 150  FEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVIS 209
             +ARFLRF+PL WNP+GRIGMRIEV+GCAY+SEVV  DG+S+LLY  D+K L PI+D+IS
Sbjct: 125  IKARFLRFIPLEWNPKGRIGMRIEVFGCAYRSEVVDLDGKSSLLYRFDQKSLSPIKDIIS 184

Query: 210  LKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDD 269
            LKFK MQS+GILLHREG +G+HITL+L + +L   +NSG AKLPST   V LTLGSLLDD
Sbjct: 185  LKFKTMQSDGILLHREGPNGDHITLQLRRARLFLLINSGEAKLPSTSTLVNLTLGSLLDD 244

Query: 270  QHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSF 329
            QHWHSVLI+ L  QVNFTVD+H HHF A+G+ + ++L++E                    
Sbjct: 245  QHWHSVLIQRLGKQVNFTVDEHRHHFHARGEFNLMNLDYE-------------------- 284

Query: 330  HGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGE 389
                                        GNVSFSC QPQ++PVTFLSSRSYLALP  SGE
Sbjct: 285  ----------------------------GNVSFSCSQPQSMPVTFLSSRSYLALPDFSGE 316

Query: 390  DKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLN 449
            ++VS TFQFRTWN+AG LLF ELQ  SG  +LFL DGKLK +L+Q G+ P ++TAG  LN
Sbjct: 317  EEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDGKLKSNLYQPGKLPSDITAGVELN 376

Query: 450  DGQWHSVSFSAKWSHMNVVVDDDTA-VQPLVAV-LIDSGDTYYFGGCLGNSSGSGCKSPL 507
            DGQWHSVS SAK +H++V VD   A   PL+    I SG TYYFGGC   S GS CKSPL
Sbjct: 377  DGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGTYYFGGCPDKSFGSKCKSPL 436

Query: 508  GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWD 567
            GGFQGC+RLI+I  K VD I VQQG+LG+F DLQIDSCGI+DRCLP+YCEHGGECSQSW 
Sbjct: 437  GGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGISDRCLPNYCEHGGECSQSWS 496

Query: 568  TFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTAD 627
            TF C+C  TGY G TCH+S+YEQSCEA+KHRGN SG YYID+DGSGPL PFL+YCNMT +
Sbjct: 497  TFHCNCTNTGYRGATCHNSIYEQSCEAYKHRGNTSGFYYIDSDGSGPLEPFLLYCNMT-E 555

Query: 628  SAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTA 687
            +AWT+++H G D   +R     +P +   F Y A   QL+A +N AE CEQ     C  +
Sbjct: 556  TAWTIIQHNGSDLTRVRNTNPENPYAGF-FEYVASMEQLQATINRAEHCEQEFTYYCKKS 614

Query: 688  RRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWT 747
            R  + +DGTPLSWWVGRTNET T WGGS PD QKCTCGLEGNCIDSQYYCNCDA +NEWT
Sbjct: 615  RLVNKQDGTPLSWWVGRTNETQTYWGGSSPDLQKCTCGLEGNCIDSQYYCNCDADRNEWT 674

Query: 748  SDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFP 807
            +DT +L+ KEHLPVT+IV+TDTG+ HSEA Y LGPLLC+GD+SFWNSASF+TE SYLHFP
Sbjct: 675  NDTGLLAYKEHLPVTKIVITDTGRLHSEAAYKLGPLLCQGDRSFWNSASFDTEASYLHFP 734

Query: 808  AFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQS 867
             FHGEL+ADV FFFKTT SSGVF+ENLGI DFIRIELR+PT VTFSFDVGNGP E++VQS
Sbjct: 735  TFHGELSADVSFFFKTTASSGVFLENLGIADFIRIELRSPTVVTFSFDVGNGPFEISVQS 794

Query: 868  PTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRG 927
            PT FNDNQWHHVR ERN+K ASLQVDQL  K QPAPADGHV LQLNSQLF+GGTATRQRG
Sbjct: 795  PTHFNDNQWHHVRVERNMKEASLQVDQLTPKTQPAPADGHVLLQLNSQLFVGGTATRQRG 854

Query: 928  FLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCA 987
            FLGCIRSLQLNG+ LDLEERA VTP V+PGC GHCS+YG LCRNGG+CRE+  G  CDC 
Sbjct: 855  FLGCIRSLQLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCT 914

Query: 988  FSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFR 1047
            FSAY GPFCSNEISAYF +GSS+ Y+FQE+Y LS+NSSS  +S + D+ L+REMI  SFR
Sbjct: 915  FSAYTGPFCSNEISAYFGSGSSVIYNFQENYLLSKNSSSHAASFHGDMKLSREMIKFSFR 974

Query: 1048 TTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVK 1107
            TTR+PSLLL+VSSFY+EYLSVI+A NGSLQIRYKL+++Q PD   FDFKNMADGQLH + 
Sbjct: 975  TTRTPSLLLFVSSFYKEYLSVIIAKNGSLQIRYKLNKYQEPDVVNFDFKNMADGQLHHIM 1034

Query: 1108 INREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGC 1167
            INREE VV +E++ + ++QV LSSGTEF+AVKSL+LG++LE +  D DT  A   GFTGC
Sbjct: 1035 INREEGVVFIEIDDNRRRQVHLSSGTEFSAVKSLVLGRILEHSDVDQDTALAGAQGFTGC 1094

Query: 1168 LSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRS 1227
            LSAV+    APLKAAL PS P  VTV GHV   + C A   + + +RE   R    A  S
Sbjct: 1095 LSAVQLSHVAPLKAALHPSHPDPVTVTGHVTE-SSCMAQPGTDATSRE---RTHSFADHS 1150

Query: 1228 GPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1284
            G +D+ EPL NA + DSAV+GG+IAVVIFILLCITAIA+RIYQQ++L K +E+K S+
Sbjct: 1151 GTIDDREPLANAIKSDSAVIGGLIAVVIFILLCITAIAVRIYQQKRLYKRSEAKRSE 1207


>gi|18640734 contactin associated protein-like 5 [Homo sapiens]
          Length = 1306

 Score = 1399 bits (3620), Expect = 0.0
 Identities = 686/1279 (53%), Positives = 898/1279 (70%), Gaps = 13/1279 (1%)

Query: 11   VLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGW 70
            VL LL +  W         +CD PLAS L   +FSSSS+L+ +H P  ++LN R G GGW
Sbjct: 10   VLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSP--AQLNWRVGTGGW 67

Query: 71   TPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIW 130
            +P  SN  QWLQ+DLG R+E+TAVATQG YGSSDWVTSY LMFSD GRNWKQY++E+SIW
Sbjct: 68   SPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQYKQEDSIW 127

Query: 131  GFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQS 190
             F GN NADSVVH++L     ARF+RF+PL WNP G+IGMR+EVYGC+YKS+V  FDG+S
Sbjct: 128  TFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDVADFDGRS 187

Query: 191  ALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNA 250
            +LLY  ++K +  ++DVISLKFK+MQ +G+L H EGQ G+HITLEL KG+L   LN G++
Sbjct: 188  SLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALHLNLGDS 247

Query: 251  KLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEI 310
            K   + +  + TLGSLLDDQHWHSVLIE +  QVNFTVDKHT HF+ KG++  LD+++E+
Sbjct: 248  KARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDALDIDYEL 307

Query: 311  SFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTV 370
            SFGGI  PG+   F +K+FHGC+ENLYYNGV++ +LAK+ K QI   GNV+FSC +PQ V
Sbjct: 308  SFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYT-GNVTFSCSEPQIV 366

Query: 371  PVTFL-SSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLK 429
            P+TF+ SS SYL LPG    D +SV+FQFRTWN+ G LL  EL  GSG+ +L L+ G L+
Sbjct: 367  PITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSLEGGILR 426

Query: 430  LSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTA--VQPLVAVLIDSGD 487
            L + +  +    +  G+ LNDG WHSVS +A+ + + + +DD+ A        V I SG+
Sbjct: 427  LVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWVQIYSGN 486

Query: 488  TYYFGGCLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGI 547
            +YYFGGC  N + S C +P+  FQGC+RLI I ++  D I VQQG+LG+F DL ID C I
Sbjct: 487  SYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSI 546

Query: 548  TDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYI 607
             DRCLP+YCEHGG CSQSW TF C+C  T YTG TCH+S+YEQSCE ++H+GN +G +YI
Sbjct: 547  KDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNTAGFFYI 606

Query: 608  DADGSGPLGPFLVYCNMTADSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLR 667
            D+DGSGPLGP  VYCN+T D  WT V+H   +   +RGA    P  A++  Y     QL 
Sbjct: 607  DSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPY-AMALDYGGSMEQLE 665

Query: 668  AAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLE 727
            A ++ +E CEQ +A  C  +R  ++ DGTP +WW+GR+NE H  WGGS P  Q+C CGL+
Sbjct: 666  AVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQCECGLD 725

Query: 728  GNCIDSQYYCNCDAGQNEWTSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRG 787
             +C+D Q++CNCDA ++EWT+DT  LS K+HLPVTQIV+TDT + +SEA + +GPL C G
Sbjct: 726  ESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGPLRCYG 785

Query: 788  DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAP 847
            D+ FWN+ SF TE SYLHFP FH E +AD+ FFFKTT  SGVF+ENLGI DFIR+E+ +P
Sbjct: 786  DRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEISSP 845

Query: 848  TEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGH 907
            +E+TF+ DVGNGP E+ VQSP+  NDNQWH+VRAERN+K  SLQVD LP+  +    +GH
Sbjct: 846  SEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRETSEEGH 905

Query: 908  VRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGH 967
             RLQLNSQLF+GGT++RQ+GFLGCIRSL LNG  +DLEERA VT GV PGC GHCS+YG 
Sbjct: 906  FRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHCSSYGS 965

Query: 968  LCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSL 1027
            +C NGG+C EK  G  CDC  S Y+GPFC  E+SA F  G+S+TY FQE Y +++N S  
Sbjct: 966  ICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTKNISLS 1025

Query: 1028 VSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQN 1087
             S++Y D   ++E I LSF TT++PSLLL+++S  ++++ V+L  NGSLQ+RY L++ + 
Sbjct: 1026 SSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHLNKEET 1085

Query: 1088 PDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL 1147
               FT D  N A+ ++H +KINRE   + ++++Q  +     S   EF  ++SL LGKV 
Sbjct: 1086 -HVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTLGKVT 1144

Query: 1148 EAAGADPDTRRAATSGFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMARCAAGA 1207
            E  G D +  +A   GF GC+S+V++   APLKAALR +  + VTV G    +   + G 
Sbjct: 1145 ENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHG---TLTESSCGF 1201

Query: 1208 ASGSPARELAPRLAGGAGRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIR 1267
               S    +   +   +   G  DE EPL NA R DSAV+GGVIAVVIFI+ CI  I  R
Sbjct: 1202 MVDSDVNAVT-TVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR 1260

Query: 1268 IYQQRKLRKENESKVSKKE 1286
               Q K +    S++ +KE
Sbjct: 1261 FLYQHK-QSHRTSQMKEKE 1278


>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
          Length = 1331

 Score = 1209 bits (3128), Expect = 0.0
 Identities = 603/1275 (47%), Positives = 834/1275 (65%), Gaps = 22/1275 (1%)

Query: 31   CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90
            CD PL S LP  +FSSSS +S S+ PG++++N+R GAGGW+P  S+ YQWLQ+D G R +
Sbjct: 35   CDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQ 94

Query: 91   VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150
            ++A+ATQG Y SSDWVT Y +++SD GRNWK Y ++ +IW FPGN N+D VV + LQ P 
Sbjct: 95   ISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQDGNIWAFPGNINSDGVVRHELQHPI 154

Query: 151  EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210
             AR++R +PL WN  GRIG+RIEVYGC+Y ++V+ FDG   L Y    K +K ++DVI+L
Sbjct: 155  IARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIAL 214

Query: 211  KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
             FK  +S G++LH EGQ G++ITLEL K KLV  LN G+ +L       ++  GSLLDD 
Sbjct: 215  NFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDH 274

Query: 271  HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330
            HWHSV+IE     +N T+D+   HF+  G+   LDL++EI+FGGI   G+  + +RK+F 
Sbjct: 275  HWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFK 334

Query: 331  GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390
            GC+E++ YNGV++T+LA++ K +   +GN+SFSC +P TVPV F ++ SYL +PG   +D
Sbjct: 335  GCMESINYNGVNITDLARRKKLEPSNVGNLSFSCVEPYTVPV-FFNATSYLEVPGRLNQD 393

Query: 391  KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGK--LKLSLFQAGQSPRNVTAGAGL 448
              SV+FQFRTWN  G L+F       G+  + L + K  + +++ Q   S  ++++G+GL
Sbjct: 394  LFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGL 453

Query: 449  NDGQWHSVSFSAKWSHMNVVVDDD--TAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSP 506
            NDGQWH V F AK +   + +D D  +AV+    + + +G+ Y+FGG L   + S     
Sbjct: 454  NDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVL 513

Query: 507  LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
               FQGC++LI + D+ V+   V Q   GSF ++ ID C I DRC+P++CEHGG+CSQ+W
Sbjct: 514  QPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTW 573

Query: 567  DTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTA 626
            D+F C C  TGY+G TCH+S+YE SCEA+KH G  S  Y+ID DGSGPLGP  VYCNMT 
Sbjct: 574  DSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSNYYWIDPDGSGPLGPLKVYCNMTE 633

Query: 627  DSAWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGT 686
            D  WT+V H       + G  +    S     Y+A   Q+ A  + AE CEQ ++  C  
Sbjct: 634  DKVWTIVSHDLQMQTPVVGY-NPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKM 692

Query: 687  ARRPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEW 746
            +R  ++ DG+P +WWVG+ NE H  WGGS P  QKC CG+E NC D +YYCNCDA   +W
Sbjct: 693  SRLLNTPDGSPYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQW 752

Query: 747  TSDTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHF 806
              D   LS K+HLPV+Q+V+ DT +  SEA  ++GPL C+GD+++WN+ASF   +SYLHF
Sbjct: 753  RKDAGFLSYKDHLPVSQVVVGDTDRQGSEAKLSVGPLRCQGDRNYWNAASFPNPSSYLHF 812

Query: 807  PAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQ 866
              F GE +AD+ F+FKT    GVF+EN+G  DFI++EL++ TEV+FSFDVGNGP E+ V+
Sbjct: 813  STFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVR 872

Query: 867  SPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR 926
            SPTP ND+QWH V AERNVK ASLQVD+LPQ+++ AP +GH RL+L SQLF+GG A  Q+
Sbjct: 873  SPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGG-AGGQQ 931

Query: 927  GFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDC 986
            GFLGCIRSL++NGV LDLEERA VT G   GC+GHC++YG  C NGG+C E+  G +CDC
Sbjct: 932  GFLGCIRSLRMNGVTLDLEERAKVTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDC 991

Query: 987  AFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL----YRDVTLTREMI 1042
            + +AYDG FC+ ++ A+F  G  + Y+FQ   T + +SSS V +          L +E I
Sbjct: 992  SNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQNSHPDLAQEEI 1051

Query: 1043 TLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQ 1102
              SF TT++P +LLY+SSF  ++L+V++   GSLQIRY L   + P     D +NMA+GQ
Sbjct: 1052 RFSFSTTKAPCILLYISSFTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQ 1111

Query: 1103 LHQVKINREEAVVMVEVNQ--SAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAA 1160
             H V I R E  + ++++   S    +  SS T FN+ KSL LGKV+E    D +  +  
Sbjct: 1112 PHSVNITRHEKTIFLKLDHYPSVSYHLPSSSDTLFNSPKSLFLGKVIETGKIDQEIHKYN 1171

Query: 1161 TSGFTGCLSAVRFGRAAPLKAALRPSGPS-RVTVRGHVAPMARCAAGAASGSPARELAPR 1219
            T GFTGCLS V+F + APLKAALR +  S  V ++G +   + C A   + SP       
Sbjct: 1172 TPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVE-SNCGASPLTLSPMSSATDP 1230

Query: 1220 LAGGAGRSGPVD------EGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIR-IYQQR 1272
                   S   D      +G+ + N   R+SA++GGVIAVVIF +LC     IR +++ +
Sbjct: 1231 WHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIRYMFRHK 1290

Query: 1273 KLRKENESKVSKKEE 1287
                 NE+K ++  E
Sbjct: 1291 GTYHTNEAKGAESAE 1305


>gi|239743797 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 944

 Score = 1201 bits (3106), Expect = 0.0
 Identities = 602/698 (86%), Positives = 613/698 (87%), Gaps = 40/698 (5%)

Query: 494  CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 553
            CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP
Sbjct: 187  CLGNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLP 246

Query: 554  SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
            SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG
Sbjct: 247  SYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 306

Query: 614  PLGPFLVYCNMTADSAWTVVR--------------------HGGPDAVTLRGAPSGHPLS 653
            PLGPFLVYCNMT  SA  +                       GG      RG P   P  
Sbjct: 307  PLGPFLVYCNMTDRSALPLAAGLCRPVMPLLCPFLLSRLRVDGGAARWPRRGDPPRCPQW 366

Query: 654  AVSFAY----------AAGAGQ----LRAAVNLAERCEQR-----LALRCGTARRPDSRD 694
            A +             AAG G+    LRAA   A R         L ++  T +     +
Sbjct: 367  APALGCVLRVRSGRGAAAGRGEPGGALRAAAGSALRDSAAPGLTSLMVKSVTFKVAFREE 426

Query: 695  -GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTSDTIVL 753
             GTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAG+NEWTSDTIVL
Sbjct: 427  YGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGRNEWTSDTIVL 486

Query: 754  SQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 813
            SQKEHLPVTQIVMTD GQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL
Sbjct: 487  SQKEHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGEL 546

Query: 814  TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 873
            TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND
Sbjct: 547  TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606

Query: 874  NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR 933
            NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR
Sbjct: 607  NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIR 666

Query: 934  SLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG 993
            SLQLNGVALDLEERATV PGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG
Sbjct: 667  SLQLNGVALDLEERATVMPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDG 726

Query: 994  PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPS 1053
            PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PS
Sbjct: 727  PFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPS 786

Query: 1054 LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 1113
            LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA
Sbjct: 787  LLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEA 846

Query: 1114 VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG 1151
            VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVL  +G
Sbjct: 847  VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLGRSG 884



 Score =  123 bits (308), Expect = 1e-27
 Identities = 62/64 (96%), Positives = 63/64 (98%)

Query: 1225 GRSGPVDEGEPLVNADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSK 1284
            GRSGPVDEGEPLVNADRRDSAV+GGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSK
Sbjct: 881  GRSGPVDEGEPLVNADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSK 940

Query: 1285 KEEC 1288
            KEEC
Sbjct: 941  KEEC 944



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 59/261 (22%), Positives = 96/261 (36%), Gaps = 24/261 (9%)

Query: 334 ENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVS 393
           E+L    + +T+  + H      +G +     +      +F +  SYL  P   GE    
Sbjct: 490 EHLPVTQIVMTDAGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTAD 549

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL-FQAGQSPRNVT--AGAGLND 450
           V F F+T   +G  +F E   G   F+        +++  F  G  P  VT  +    ND
Sbjct: 550 VCFFFKTTVSSG--VFME-NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFND 606

Query: 451 GQWHSVSFSAKWSHMNVVVDD-DTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            QWH V         ++ VD     +QP  A   V +      + GG             
Sbjct: 607 NQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQR------- 659

Query: 507 LGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSW 566
             GF GC+R + +   A+D  L ++  +    +     C          C +GG C +  
Sbjct: 660 --GFLGCIRSLQLNGVALD--LEERATVMPGVE---PGCAGHCSTYGHLCRNGGRCREKR 712

Query: 567 DTFSCDCLGTGYTGETCHSSL 587
              +CDC  + Y G  C + +
Sbjct: 713 RGVTCDCAFSAYDGPFCSNEI 733



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 212 FKAMQSNGILLHREGQHGNHITLEL-IKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
           FK   S+G+ +   G   + I +EL    ++ F  + GN     T+   T       +D 
Sbjct: 554 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 607

Query: 271 HWHSVLIELLDTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGILSPGRSRAFTRKS 328
            WH V  E      +  VD+     Q A  D    L LN ++  GG        A  ++ 
Sbjct: 608 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT-------ATRQRG 660

Query: 329 FHGCLENLYYNGV 341
           F GC+ +L  NGV
Sbjct: 661 FLGCIRSLQLNGV 673


>gi|4505463 contactin associated protein 1 precursor [Homo sapiens]
          Length = 1384

 Score =  884 bits (2284), Expect = 0.0
 Identities = 455/1212 (37%), Positives = 690/1212 (56%), Gaps = 60/1212 (4%)

Query: 31   CDSPLASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWTPLVSNKYQWLQIDLGERME 90
            CD  L   L   S  +SS  S    P F+RL+   G  GW+P + +   WLQIDL ++  
Sbjct: 25   CDEELVGPLYARSLGASSYYSLLTAPRFARLH---GISGWSPRIGDPNPWLQIDLMKKHR 81

Query: 91   VTAVATQGGYGSSDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPF 150
            + AVATQG + S DWVT Y+L++ D   +W  + +      F GN N  +VV + L   F
Sbjct: 82   IRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNSTFFGNVNESAVVRHDLHFHF 141

Query: 151  EARFLRFLPLAWNPRGRIGMRIEVYGCAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISL 210
             AR++R +PLAWNPRG+IG+R+ +YGC YK++++YFDG  A+ Y   +   + + DV + 
Sbjct: 142  TARYIRIVPLAWNPRGKIGLRLGLYGCPYKADILYFDGDDAISYRFPRGVSRSLWDVFAF 201

Query: 211  KFKAMQSNGILLHREGQHGNHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270
             FK  + +G+LLH EG  G+++TLEL    L+  ++ G++ +       T++ G +L+DQ
Sbjct: 202  SFKTEEKDGLLLHAEGAQGDYVTLELEGAHLLLHMSLGSSPIQPRPGHTTVSAGGVLNDQ 261

Query: 271  HWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFH 330
            HWH V ++     VNFT+D +   F   GD   L+L+ E+  GG++   R     R +F 
Sbjct: 262  HWHYVRVDRFGRDVNFTLDGYVQRFILNGDFERLNLDTEMFIGGLVGAARKNLAYRHNFR 321

Query: 331  GCLENLYYNGVDVTELAKKHKPQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGED 390
            GC+EN+ +N V++ +LA +   +I   G V+F C  P   P+ F    +++ +PG     
Sbjct: 322  GCIENVIFNRVNIADLAVRRHSRITFEGKVAFRCLDPVPHPINFGGPHNFVQVPGFPRRG 381

Query: 391  KVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLND 450
            +++V+F+FRTW+  G LLF  L  G G   L L +G++ +S+ Q+G+      AG  LND
Sbjct: 382  RLAVSFRFRTWDLTGLLLFSRLGDGLGHVELTLSEGQVNVSIAQSGRKKLQFAAGYRLND 441

Query: 451  GQWHSVSFSAKWSHMNVVVDDDTAVQPLVA--VLIDSGDTYYFGGCLGNSSGSGCKSPLG 508
            G WH V+F A+ +H  + +DD    +  V+  +LI +G +Y+FGGC   +S   C S   
Sbjct: 442  GFWHEVNFVAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPASRWDCHSNQT 501

Query: 509  GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDT 568
             F GC+ L+ +  + V+  LV+   LG + ++  D+CGITDRC P+ CEH G C QSWD 
Sbjct: 502  AFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNMCEHDGRCYQSWDD 561

Query: 569  FSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLGPFLVYCNMTADS 628
            F C C  TGY GETCH+ LY++SCEA++  G  SG + ID DGSGPL PF+VYC++  + 
Sbjct: 562  FICYCELTGYKGETCHTPLYKESCEAYRLSGKTSGNFTIDPDGSGPLKPFVVYCDIRENR 621

Query: 629  AWTVVRHGGPDAVTLRGAPSGHPLSAVSFAYAAGAGQLRAAVNLAERCEQRLALRCGTAR 688
            AWTVVRH       + G+    P       + A   ++ A  N ++ CEQ +   C  +R
Sbjct: 622  AWTVVRHDRLWTTRVTGSSMERPFLGAIQYWNASWEEVSALANASQHCEQWIEFSCYNSR 681

Query: 689  RPDSRDGTPLSWWVGRTNETHTSWGGSLPDAQKCTCGLEGNCIDSQYYCNCDAGQNEWTS 748
              ++  G P S+W+GR  E H  WGGS P  Q+C CGL+ +C+D   YCNCDA Q +W +
Sbjct: 682  LLNTAGGYPYSFWIGRNEEQHFYWGGSQPGIQRCACGLDRSCVDPALYCNCDADQPQWRT 741

Query: 749  DTIVLSQKEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPA 808
            D  +L+  +HLPVTQ+V+ DT +  SEA + L PL C GD++ WN+ SF+T  + L FP 
Sbjct: 742  DKGLLTFVDHLPVTQVVIGDTNRSTSEAQFFLRPLRCYGDRNSWNTISFHTGAA-LRFPP 800

Query: 809  FHGELTADVCFFFKTTVSSGVFMENLG------ITDFIRIELRAPTEVTFSFDVGNGPCE 862
                 + DV F+F+T+  SGVF+EN+G         ++R+EL    +V F+FDVGNG   
Sbjct: 801  IRANHSLDVSFYFRTSAPSGVFLENMGGPYCQWRRPYVRVELNTSRDVVFAFDVGNGDEN 860

Query: 863  VTVQSPT-PFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGT 921
            +TV S    FND++WH VRAE NVK A L+VD  P  ++P P   ++ ++ +  L++G  
Sbjct: 861  LTVHSDDFEFNDDEWHLVRAEINVKQARLRVDHRPWVLRPMPLQTYIWMEYDQPLYVGSA 920

Query: 922  ATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRG 981
              ++R F+GC+R+++LNGV L+LE RA  + G  P C GHC+     C +GGRC E+   
Sbjct: 921  ELKRRPFVGCLRAMRLNGVTLNLEGRANASEGTSPNCTGHCAHPRLPCFHGGRCVERYSY 980

Query: 982  VTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSL---------- 1031
             TCDC  +A+DGP+C+++I  +F  G+ M Y+ Q     +    S + S           
Sbjct: 981  YTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYNLQSALRSAAREFSHMLSRPVPGYEPGYI 1040

Query: 1032 -------------------------------YRD--VTLTREMITLSFRTTRSPSLLLYV 1058
                                           YR     +T E ++ SF T+ +P++LLYV
Sbjct: 1041 PGYDTPGYVPGYHGPGYRLPDYPRPGRPVPGYRGPVYNVTGEEVSFSFSTSSAPAVLLYV 1100

Query: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR--EEAVVM 1116
            SSF  +Y++V++ ++G+LQ+RY+L    +P  +    + + DGQ H + I R      + 
Sbjct: 1101 SSFVRDYMAVLIKDDGTLQLRYQLG--TSPYVYQLTTRPVTDGQPHSINITRVYRNLFIQ 1158

Query: 1117 VEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRA 1176
            V+     +++  L   ++ ++ K+L LG+V+E    DP+ +R  T GF+GCLS VRF   
Sbjct: 1159 VDYFPLTEQKFSLLVDSQLDSPKALYLGRVMETGVIDPEIQRYNTPGFSGCLSGVRFNNV 1218

Query: 1177 APLKAALRPSGP 1188
            APLK   R   P
Sbjct: 1219 APLKTHFRTPRP 1230


>gi|239743729 PREDICTED: similar to contactin associated
           protein-like 3B [Homo sapiens]
          Length = 380

 Score =  723 bits (1866), Expect = 0.0
 Identities = 352/357 (98%), Positives = 354/357 (99%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHGPGFSR 60
           MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCD+PLASALPRSSFSSSSELSSSHGPGFSR
Sbjct: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDAPLASALPRSSFSSSSELSSSHGPGFSR 60

Query: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120
           LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW
Sbjct: 61  LNRRDGAGGWTPLVSNKYQWLQIDLGERMEVTAVATQGGYGSSDWVTSYLLMFSDGGRNW 120

Query: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180
           KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK
Sbjct: 121 KQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGCAYK 180

Query: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGK 240
           SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIK K
Sbjct: 181 SEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKRK 240

Query: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGD 300
           LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELL TQVNFTVDKHTHHFQAKGD
Sbjct: 241 LVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLHTQVNFTVDKHTHHFQAKGD 300

Query: 301 SSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM 357
           SSNLDLNFEISFGGI +PGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM
Sbjct: 301 SSNLDLNFEISFGGIPTPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQILMM 357



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 11/88 (12%)

Query: 394 VTFQFRTWNRAGHLLFGELQRGSG--------SFVLFLKDGKLKLSLFQAGQSPRNVTAG 445
           ++ +F+     G LL  E Q G+           V FL  G  KL    A   P  +T G
Sbjct: 208 ISLKFKAMQSNGILLHREGQHGNHITLELIKRKLVFFLNSGNAKLPSTIA---PVTLTLG 264

Query: 446 AGLNDGQWHSVSFSAKWSHMNVVVDDDT 473
           + L+D  WHSV      + +N  VD  T
Sbjct: 265 SLLDDQHWHSVLIELLHTQVNFTVDKHT 292



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 16/133 (12%)

Query: 821 FKTTVSSGVFMENLGIT-DFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTP-----FNDN 874
           FK   S+G+ +   G   + I +EL    ++ F  + GN     T+   T       +D 
Sbjct: 212 FKAMQSNGILLHREGQHGNHITLEL-IKRKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQ 270

Query: 875 QWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTAT-------RQRG 927
            WH V  E      +  VD+     Q A  D    L LN ++  GG  T        ++ 
Sbjct: 271 HWHSVLIELLHTQVNFTVDKHTHHFQ-AKGDSS-NLDLNFEISFGGIPTPGRSRAFTRKS 328

Query: 928 FLGCIRSLQLNGV 940
           F GC+ +L  NGV
Sbjct: 329 FHGCLENLYYNGV 341


>gi|169184330 PREDICTED: novel protein similar to contactin associated
            protein-like 3 (CNTNAP3) [Homo sapiens]
          Length = 291

 Score =  550 bits (1416), Expect = e-156
 Identities = 284/290 (97%), Positives = 288/290 (99%)

Query: 999  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 1058
            +ISAYFATGSSMTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYV
Sbjct: 2    KISAYFATGSSMTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYV 61

Query: 1059 SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 1118
            SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE
Sbjct: 62   SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVE 121

Query: 1119 VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGRAAP 1178
            VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFG AAP
Sbjct: 122  VNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGCAAP 181

Query: 1179 LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 1238
            LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN
Sbjct: 182  LKAALRPSGPSRVTVRGHVAPMARCAAGAASGSPARELAPRLAGGAGRSGPVDEGEPLVN 241

Query: 1239 ADRRDSAVMGGVIAVVIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 1288
            ADRRDSAV+GGVIAV IFILLCITAIAIRIYQQRKLRKENESKVSKKEEC
Sbjct: 242  ADRRDSAVIGGVIAVEIFILLCITAIAIRIYQQRKLRKENESKVSKKEEC 291


>gi|239758135 PREDICTED: similar to cell recognition molecule CASPR3
            [Homo sapiens]
          Length = 140

 Score =  265 bits (678), Expect = 2e-70
 Identities = 136/138 (98%), Positives = 138/138 (100%)

Query: 1010 MTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVI 1069
            MTYHFQEHYTLSENSSSLVSSL+RDVTLTREMITLSFRTTR+PSLLLYVSSFYEEYLSVI
Sbjct: 1    MTYHFQEHYTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSFYEEYLSVI 60

Query: 1070 LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 1129
            LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL
Sbjct: 61   LANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVIL 120

Query: 1130 SSGTEFNAVKSLILGKVL 1147
            SSGTEFNAVKSLILGKVL
Sbjct: 121  SSGTEFNAVKSLILGKVL 138


>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
          Length = 1477

 Score =  216 bits (549), Expect = 1e-55
 Identities = 253/1062 (23%), Positives = 436/1062 (41%), Gaps = 189/1062 (17%)

Query: 183  VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
            +  F G     Y L + P++   D I+L FK +Q NG++LH  G+  +++ L L  G + 
Sbjct: 283  IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 341

Query: 243  FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIEL----------------LD----- 281
              +N G+    + + PV        +D  WH V +                  +D     
Sbjct: 342  LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTRNLRQHSGIGHAMVTISVDGILTT 397

Query: 282  ---TQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYY 338
               TQ ++T+      F   G  S  DL           PG        +F GCL+ + Y
Sbjct: 398  TGYTQEDYTMLGSDDFFYVGGSPSTADL-----------PGSP---VSNNFMGCLKEVVY 443

Query: 339  NGVDV----TELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVS 393
               DV    + LAK+  P++ + G V+F C    T+ P+TF +  S+++LP  + +   S
Sbjct: 444  KNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGS 503

Query: 394  VTFQFRTWNRAGHLLF--GELQRGSGS----------FVLFLKDGKLKLSLFQAGQSPRN 441
            ++F FRT    G +LF  G+ +    +          F + + DG L L L     + + 
Sbjct: 504  ISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKI 563

Query: 442  VTAGAGLNDGQWHSVSFSAKWSHMNVVVDD--DTAVQPLVAVLIDSGDTYYFGGCLGNSS 499
                  +NDG+W+ V F        + V+        P  + ++D  D  Y GG   N +
Sbjct: 564  KALLKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKA 623

Query: 500  GSGCKSPLG------GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDR-CL 552
            G    + +       G+ GC+R + I  ++ D  + Q   + S   ++      T + CL
Sbjct: 624  GLVFPTEVWTALLNYGYVGCIRDLFIDGQSKD--IRQMAEVQSTAGVKPSCSKETAKPCL 681

Query: 553  PSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGS 612
             + C++ G C   W+ + CDC GTGY G         +SCE             +  DGS
Sbjct: 682  SNPCKNNGMCRDGWNRYVCDCSGTGYLG---------RSCEREAT--------VLSYDGS 724

Query: 613  GPLGPFLVYCNMTADSAWTVVRHGGPDAVTLR-GAPSGHPL--------SAVSFAYAAGA 663
                       M       VV H   + V+LR  +   + +        SA +      A
Sbjct: 725  -----------MFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDA 773

Query: 664  GQLRAAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHT--------SWGGS 715
            G+++  VNL       + + C +++ P+    T  + +    NE HT        S   +
Sbjct: 774  GRVKLTVNL-----DCIRINCNSSKGPE----TLFAGYNLNDNEWHTVRVVRRGKSLKLT 824

Query: 716  LPDAQKCTCGLEGNCIDSQYYCNCDAG---QNEWTSD--TIVLSQKEHLPVTQIVMTDTG 770
            + D Q  T  + G+    +++ N + G   +  + S   +  +   + L    +   D  
Sbjct: 825  VDDQQAMTGQMAGDHTRLEFH-NIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLC 883

Query: 771  QPHSEADYTLGPLLCRGDKSFW------NSASFNTETSYLHFPAFHGELTADVCFFFKTT 824
            + + + DY      C  +  F       +  +F T++SY+         +  + F FKTT
Sbjct: 884  K-NGDIDY------CELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTT 936

Query: 825  VSSGVFMENLGI-TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAER 883
               G+ + N G   DFI +EL     + + FD+GNG   +   S  P NDNQWH+V   R
Sbjct: 937  SLDGLILYNSGDGNDFIVVEL-VKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISR 995

Query: 884  NVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR-----------QRGFLGCI 932
            +   ++L   ++  K+      G   L L S L+IGG A             + GF GC+
Sbjct: 996  DT--SNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCL 1053

Query: 933  RSLQLNGVALDLEERATVTPG-VEPGCAGHCST-YGHLCRNGGRCREKRRGVTCDCAFSA 990
             S+ LNG   DL   A    G +E GC G  +T     C N G C ++  G +CDC+ ++
Sbjct: 1054 ASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTS 1113

Query: 991  YDGPFCSNEISAYFAT--GSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRT 1048
            + GP C++  + Y  +  G  +TY +  +   S  +               + + + F T
Sbjct: 1114 FSGPLCNDPGTTYIFSKGGGQITYKWPPNDRPSTRA---------------DRLAIGFST 1158

Query: 1049 TRSPSLLLYV--SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKN--MADGQLH 1104
             +  ++L+ V  SS   +YL + + + G + +++ +      D    +  N  + DG+ H
Sbjct: 1159 VQKEAVLVRVDSSSGLGDYLELHI-HQGKIGVKFNV----GTDDIAIEESNAIINDGKYH 1213

Query: 1105 QVKINRE--EAVVMVEVNQSAKKQVILSSGTEFNAVKSLILG 1144
             V+  R    A + V+     ++       T FN+  ++I+G
Sbjct: 1214 VVRFTRSGGNATLQVDSWPVIERYPAGRQLTIFNSQATIIIG 1255



 Score =  120 bits (301), Expect = 8e-27
 Identities = 115/419 (27%), Positives = 182/419 (43%), Gaps = 21/419 (5%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F++ ++ GIL+    +   + + LE
Sbjct: 712  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 770

Query: 236  LIKGKLVFFLNSGNAKLP--STIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVD-KHT 292
            L  G++   +N    ++   S+  P TL  G  L+D  WH+V +      +  TVD +  
Sbjct: 771  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 830

Query: 293  HHFQAKGDSSNLDL-NFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHK 351
               Q  GD + L+  N E    GI++  R  +    +F G L++L +NG+   +L K   
Sbjct: 831  MTGQMAGDHTRLEFHNIET---GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGD 887

Query: 352  PQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGE 411
                 + N  F        PVTF +  SY+AL        + + FQF+T +  G +L+  
Sbjct: 888  IDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNS 946

Query: 412  LQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVV 469
               G+   V+ L  G L   +F  G     +   +   LND QWH+V  S   S+++ V 
Sbjct: 947  GD-GNDFIVVELVKGYLHY-VFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVK 1004

Query: 470  DDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVD 525
             D      + A    +D     Y GG    +  S  K      GFQGCL  + +  +  D
Sbjct: 1005 IDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPD 1064

Query: 526  PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
             I     AL     ++    G +  C    C + G C Q WD FSCDC  T ++G  C+
Sbjct: 1065 LI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN 1120



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 73/305 (23%), Positives = 126/305 (41%), Gaps = 36/305 (11%)

Query: 800  ETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVG 857
            E  +  FP ++    +++ F  KT  + G+  + ++ G  DF+ + L     +  SF + 
Sbjct: 37   EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 858  NGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLF 917
                  T+ + TP ND  WH VR  R  +  +L +DQ+  K     +     + + S LF
Sbjct: 97   CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRR-DMTVFSGLF 154

Query: 918  IGG--------------TATRQR-GFLGCIRSLQLNGV--------ALDLEERATVTPGV 954
            +GG               + R+R  F G IR +++N           + L++    + G 
Sbjct: 155  VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214

Query: 955  EPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEIS-----AYFATGSS 1009
             P  AG     G +C NGG C        CDC+ + + G  CS E +     A+   G  
Sbjct: 215  SPCEAGE-EGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEGLAHLMMGDQ 273

Query: 1010 MTYHFQEHY--TLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLS 1067
                 +E Y  T   +           +  + + ITLSF+T +   L+L+      +Y++
Sbjct: 274  GKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGK-SADYVN 332

Query: 1068 VILAN 1072
            + L N
Sbjct: 333  LALKN 337



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 34/213 (15%)

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFV--LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDG 451
           ++FQ +T +  G +L+ +   G   F+  +  + G+L+LS       P  + A   +NDG
Sbjct: 54  MSFQLKTRSARGLVLYFD-DEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDG 112

Query: 452 QWHSVSFSAKWSHMNVVVDDDTAVQPLVA-----VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            WHSV    ++ +  + +D   A    V      + + SG   + GG       +  K  
Sbjct: 113 AWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALKLT 170

Query: 507 LGG------FQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDS----------CGITDR 550
           L        F+G +R + +    V P+           ++++D           C   + 
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQVLPV--------DSGEVKLDDEPPNSGGGSPCEAGEE 222

Query: 551 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
                C +GG CS   D   CDC  TG+ G+ C
Sbjct: 223 GEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDC 255



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 60/272 (22%), Positives = 107/272 (39%), Gaps = 50/272 (18%)

Query: 706 NETHTSWGGSLPDAQK------CTCGLEGNCIDSQYYCNCDA----GQNEWTSDTIVLSQ 755
           +E   S GGS  +A +      C  G   + +D Q  C+C      G++    D  V   
Sbjct: 206 DEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEDNNVEG- 264

Query: 756 KEHLPVTQIVMTDTGQPHSEADYTLGPLLCRGDKSFWNSASFNTETSYLHFPAFHGELTA 815
                +  ++M D G+   + +Y           +F  S  F  + S     +   E+T 
Sbjct: 265 -----LAHLMMGDQGKSKGKEEYIA---------TFKGSEYFCYDLSQNPIQSSSDEITL 310

Query: 816 DVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFNDN 874
                FKT   +G+ +      D++ + L+    V+   ++G+G  E  V+     FNDN
Sbjct: 311 S----FKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLGSGAFEALVEPVNGKFNDN 365

Query: 875 QWHHVRAERNVKGAS--------LQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR-- 924
            WH V+  RN++  S        + VD +         D +  L  +   ++GG+ +   
Sbjct: 366 AWHDVKVTRNLRQHSGIGHAMVTISVDGILTTTGYTQED-YTMLGSDDFFYVGGSPSTAD 424

Query: 925 ------QRGFLGCIRSL--QLNGVALDLEERA 948
                    F+GC++ +  + N V L+L   A
Sbjct: 425 LPGSPVSNNFMGCLKEVVYKNNDVRLELSRLA 456



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 37/181 (20%), Positives = 73/181 (40%), Gaps = 16/181 (8%)

Query: 206  DVISLKFKAMQSNGILLHREGQHG--NHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTL 263
            D +++ F  +Q   +L+  +   G  +++ L + +GK+    N G   +    +      
Sbjct: 1150 DRLAIGFSTVQKEAVLVRVDSSSGLGDYLELHIHQGKIGVKFNVGTDDIAIEES------ 1203

Query: 264  GSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISFGGILSPGRSRA 323
             ++++D  +H V            VD        +   +   L    S   I+  G+ + 
Sbjct: 1204 NAIINDGKYHVVRFTRSGGNATLQVDSWP---VIERYPAGRQLTIFNSQATIIIGGKEQG 1260

Query: 324  FTRKSFHGCLENLYYNGVDVTELAKKHKPQILMMGNVSF--SCPQPQTVPVTFLSSRSYL 381
               + F G L  LYYNG+ V  +A ++   I ++GNV      P   T   T  + +S +
Sbjct: 1261 ---QPFQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEM 1317

Query: 382  A 382
            +
Sbjct: 1318 S 1318


>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
          Length = 1547

 Score =  214 bits (545), Expect = 4e-55
 Identities = 248/1032 (24%), Positives = 427/1032 (41%), Gaps = 172/1032 (16%)

Query: 183  VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
            +  F G     Y L + P++   D I+L FK +Q NG++LH  G+  +++ L L  G + 
Sbjct: 316  IATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHT-GKSADYVNLALKNGAVS 374

Query: 243  FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSV---------------LIELLDTQVNFT 287
              +N G+    + + PV        +D  WH V               ++  L   V  +
Sbjct: 375  LVINLGSGAFEALVEPVN----GKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTIS 430

Query: 288  VDKH-THHFQAKGDSSNLDLNFEISFGGILS----PGRSRAFTRKSFHGCLENLYYNGVD 342
            VD   T     + D + L  +     GG  S    PG        +F GCL+ + Y   D
Sbjct: 431  VDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSP---VSNNFMGCLKEVVYKNND 487

Query: 343  V----TELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVSVTFQ 397
            V    + LAK+  P++ + G V+F C    T+ P+TF +  S+++LP  + +   S++F 
Sbjct: 488  VRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFD 547

Query: 398  FRTWNRAGHLLF--GELQRGSGS----------FVLFLKDGKLKLSLFQAGQSPRNVTAG 445
            FRT    G +LF  G+ +    +          F + + DG L L L     + +     
Sbjct: 548  FRTTEPNGLILFSHGKPRHQKDAKHPQMIKVDFFAIEMLDGHLYLLLDMGSGTIKIKALL 607

Query: 446  AGLNDGQWHSVSFSAKWSHMNVVVDD--DTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGC 503
              +NDG+W+ V F        + V+        P  + ++D  D  Y GG   N +G   
Sbjct: 608  KKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDELYLGGLPENKAGLVF 667

Query: 504  KSPLG------GFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDR-CLPSYC 556
             + +       G+ GC+R + I  ++ D  + Q   + S   ++      T + CL + C
Sbjct: 668  PTEVWTALLNYGYVGCIRDLFIDGQSKD--IRQMAEVQSTAGVKPSCSKETAKPCLSNPC 725

Query: 557  EHGGECSQSWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSGPLG 616
            ++ G C   W+ + CDC GTGY G         +SCE             +  DGS    
Sbjct: 726  KNNGMCRDGWNRYVCDCSGTGYLG---------RSCEREAT--------VLSYDGS---- 764

Query: 617  PFLVYCNMTADSAWTVVRHGGPDAVTLR-GAPSGHPL--------SAVSFAYAAGAGQLR 667
                   M       VV H   + V+LR  +   + +        SA +      AG+++
Sbjct: 765  -------MFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRDSADTLRLELDAGRVK 817

Query: 668  AAVNLAERCEQRLALRCGTARRPDSRDGTPLSWWVGRTNETHT--------SWGGSLPDA 719
              VNL       + + C +++ P+    T  + +    NE HT        S   ++ D 
Sbjct: 818  LTVNL-----DCIRINCNSSKGPE----TLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQ 868

Query: 720  QKCTCGLEGNCIDSQYYCNCDAG---QNEWTSD--TIVLSQKEHLPVTQIVMTDTGQPHS 774
            Q  T  + G+    +++ N + G   +  + S   +  +   + L    +   D  + + 
Sbjct: 869  QAMTGQMAGDHTRLEFH-NIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCK-NG 926

Query: 775  EADYTLGPLLCRGDKSFW------NSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSG 828
            + DY      C  +  F       +  +F T++SY+         +  + F FKTT   G
Sbjct: 927  DIDY------CELNARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDG 980

Query: 829  VFMENLGI-TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKG 887
            + + N G   DFI +EL     + + FD+GNG   +   S  P NDNQWH+V   R+   
Sbjct: 981  LILYNSGDGNDFIVVEL-VKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDT-- 1037

Query: 888  ASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATR-----------QRGFLGCIRSLQ 936
            ++L   ++  K+      G   L L S L+IGG A             + GF GC+ S+ 
Sbjct: 1038 SNLHTVKIDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVD 1097

Query: 937  LNGVALDLEERATVTPG-VEPGCAGHCST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGP 994
            LNG   DL   A    G +E GC G  +T     C N G C ++  G +CDC+ +++ GP
Sbjct: 1098 LNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGP 1157

Query: 995  FCSNEISAYFAT--GSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSP 1052
             C++  + Y  +  G  +TY +  +   S  +               + + + F T +  
Sbjct: 1158 LCNDPGTTYIFSKGGGQITYKWPPNDRPSTRA---------------DRLAIGFSTVQKE 1202

Query: 1053 SLLLYV--SSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKN--MADGQLHQVKI 1108
            ++L+ V  SS   +YL + + + G + +++ +      D    +  N  + DG+ H V+ 
Sbjct: 1203 AVLVRVDSSSGLGDYLELHI-HQGKIGVKFNV----GTDDIAIEESNAIINDGKYHVVRF 1257

Query: 1109 NREEAVVMVEVN 1120
             R      ++V+
Sbjct: 1258 TRSGGNATLQVD 1269



 Score =  120 bits (301), Expect = 8e-27
 Identities = 115/419 (27%), Positives = 182/419 (43%), Gaps = 21/419 (5%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F++ ++ GIL+    +   + + LE
Sbjct: 752  CEREATVLSYDGSMFMKIQLPVVMHTEAEDV-SLRFRSQRAYGILMATTSRDSADTLRLE 810

Query: 236  LIKGKLVFFLNSGNAKLP--STIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVD-KHT 292
            L  G++   +N    ++   S+  P TL  G  L+D  WH+V +      +  TVD +  
Sbjct: 811  LDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLTVDDQQA 870

Query: 293  HHFQAKGDSSNLDL-NFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHK 351
               Q  GD + L+  N E    GI++  R  +    +F G L++L +NG+   +L K   
Sbjct: 871  MTGQMAGDHTRLEFHNIET---GIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGD 927

Query: 352  PQILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGE 411
                 + N  F        PVTF +  SY+AL        + + FQF+T +  G +L+  
Sbjct: 928  IDYCEL-NARFGFRNIIADPVTFKTKSSYVALATLQAYTSMHLFFQFKTTSLDGLILYNS 986

Query: 412  LQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVV 469
               G+   V+ L  G L   +F  G     +   +   LND QWH+V  S   S+++ V 
Sbjct: 987  GD-GNDFIVVELVKGYLHY-VFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTSNLHTVK 1044

Query: 470  DDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVD 525
             D      + A    +D     Y GG    +  S  K      GFQGCL  + +  +  D
Sbjct: 1045 IDTKITTQITAGARNLDLKSDLYIGGVAKETYKSLPKLVHAKEGFQGCLASVDLNGRLPD 1104

Query: 526  PILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
             I     AL     ++    G +  C    C + G C Q WD FSCDC  T ++G  C+
Sbjct: 1105 LI---SDALFCNGQIERGCEGPSTTCQEDSCSNQGVCLQQWDGFSCDCSMTSFSGPLCN 1160



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 58/226 (25%), Positives = 96/226 (42%), Gaps = 28/226 (12%)

Query: 800  ETSYLHFPAFHGELTADVCFFFKTTVSSGV--FMENLGITDFIRIELRAPTEVTFSFDVG 857
            E  +  FP ++    +++ F  KT  + G+  + ++ G  DF+ + L     +  SF + 
Sbjct: 37   EGQWTRFPKWNACCESEMSFQLKTRSARGLVLYFDDEGFCDFLELILTRGGRLQLSFSIF 96

Query: 858  NGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLF 917
                  T+ + TP ND  WH VR  R  +  +L +DQ+  K     +     + + S LF
Sbjct: 97   CAE-PATLLADTPVNDGAWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRR-DMTVFSGLF 154

Query: 918  IGG--------------TATRQR-GFLGCIRSLQLNGV--------ALDLEERATVTPGV 954
            +GG               + R+R  F G IR +++N           + L++    + G 
Sbjct: 155  VGGLPPELRAAALKLTLASVREREPFKGWIRDVRVNSSQVLPVDSGEVKLDDEPPNSGGG 214

Query: 955  EPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEI 1000
             P  AG     G +C NGG C        CDC+ + + G  CS EI
Sbjct: 215  SPCEAGE-EGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 49/217 (22%), Positives = 86/217 (39%), Gaps = 34/217 (15%)

Query: 394 VTFQFRTWNRAGHLLFGELQRGSGSFV--LFLKDGKLKLSLFQAGQSPRNVTAGAGLNDG 451
           ++FQ +T +  G +L+ +   G   F+  +  + G+L+LS       P  + A   +NDG
Sbjct: 54  MSFQLKTRSARGLVLYFD-DEGFCDFLELILTRGGRLQLSFSIFCAEPATLLADTPVNDG 112

Query: 452 QWHSVSFSAKWSHMNVVVDDDTAVQPLVA-----VLIDSGDTYYFGGCLGNSSGSGCKSP 506
            WHSV    ++ +  + +D   A    V      + + SG   + GG       +  K  
Sbjct: 113 AWHSVRIRRQFRNTTLFIDQVEAKWVEVKSKRRDMTVFSG--LFVGGLPPELRAAALKLT 170

Query: 507 LGG------FQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDS----------CGITDR 550
           L        F+G +R + +    V P+           ++++D           C   + 
Sbjct: 171 LASVREREPFKGWIRDVRVNSSQVLPV--------DSGEVKLDDEPPNSGGGSPCEAGEE 222

Query: 551 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCHSSL 587
                C +GG CS   D   CDC  TG+ G+ C   +
Sbjct: 223 GEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEI 259



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 51/210 (24%), Positives = 85/210 (40%), Gaps = 34/210 (16%)

Query: 706 NETHTSWGGSLPDAQK------CTCGLEGNCIDSQYYCNCDAG--QNEWTSDTIVLSQKE 757
           +E   S GGS  +A +      C  G   + +D Q  C+C     + +  S  I    + 
Sbjct: 206 DEPPNSGGGSPCEAGEEGEGGVCLNGGVCSVVDDQAVCDCSRTGFRGKDCSQEIKFGLQC 265

Query: 758 HLPVT-------QIVMTDTGQPHSEADYTLGPL--LCRGDK-----------SFWNSASF 797
            LPV        +    +T +P +E D  +  L  L  GD+           +F  S  F
Sbjct: 266 VLPVLLHDNDQGKYCCINTAKPLTEKDNNVEGLAHLMMGDQGKSKGKEEYIATFKGSEYF 325

Query: 798 NTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVG 857
             + S     +   E+T      FKT   +G+ +      D++ + L+    V+   ++G
Sbjct: 326 CYDLSQNPIQSSSDEITLS----FKTLQRNGLMLHTGKSADYVNLALKNGA-VSLVINLG 380

Query: 858 NGPCEVTVQSPT-PFNDNQWHHVRAERNVK 886
           +G  E  V+     FNDN WH V+  RN++
Sbjct: 381 SGAFEALVEPVNGKFNDNAWHDVKVTRNLR 410



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 2/56 (3%)

Query: 329  FHGCLENLYYNGVDVTELAKKHKPQILMMGNVSF--SCPQPQTVPVTFLSSRSYLA 382
            F G L  LYYNG+ V  +A ++   I ++GNV      P   T   T  + +S ++
Sbjct: 1333 FQGQLSGLYYNGLKVLNMAAENDANIAIVGNVRLVGEVPSSMTTESTATAMQSEMS 1388



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 3/82 (3%)

Query: 835  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ 894
            G+ D++ + +    ++   F+VG     +  +S    ND ++H VR  R+   A+LQVD 
Sbjct: 1213 GLGDYLELHIHQG-KIGVKFNVGTDDIAIE-ESNAIINDGKYHVVRFTRSGGNATLQVDS 1270

Query: 895  LPQ-KMQPAPADGHVRLQLNSQ 915
             P  +  PA  + + RL +  Q
Sbjct: 1271 WPVIERYPAGNNDNERLAIARQ 1292


>gi|239752499 PREDICTED: similar to cell recognition molecule Caspr2,
            partial [Homo sapiens]
          Length = 140

 Score =  146 bits (368), Expect = 1e-34
 Identities = 74/74 (100%), Positives = 74/74 (100%)

Query: 1074 GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 1133
            GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT
Sbjct: 2    GSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGT 61

Query: 1134 EFNAVKSLILGKVL 1147
            EFNAVKSLILGKVL
Sbjct: 62   EFNAVKSLILGKVL 75


>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
          Length = 1642

 Score =  135 bits (341), Expect = 2e-31
 Identities = 119/446 (26%), Positives = 191/446 (42%), Gaps = 60/446 (13%)

Query: 183 VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
           V  F G     Y L   P++   D I+L F+ +Q NG++LH  G+  +++ L L  G + 
Sbjct: 265 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVW 323

Query: 243 FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIE--------LLDTQVNFTVDKH-TH 293
             +N G+    + + PV        +D  WH V +         +    V  +VD   T 
Sbjct: 324 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTRNLRQHAGIGHAMVTISVDGILTT 379

Query: 294 HFQAKGDSSNLDLNFEISFGGILSPGRSR---AFTRKSFHGCLENLYYNGVD----VTEL 346
               + D + L  +     GG  SP  +    +    +F GCL+++ Y   D    ++ L
Sbjct: 380 TGYTQEDYTMLGSDDFFYIGG--SPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRL 437

Query: 347 AKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAG 405
           AK+  P++ + G++SF C     + PVTF S  +++ALP  S +   S++  FRT    G
Sbjct: 438 AKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNG 497

Query: 406 HLLFGELQRGSGS------------FVLFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQW 453
            LLF + +R  G             F + L DG L L L       +   +   +NDG+W
Sbjct: 498 LLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEW 557

Query: 454 HSVSFSAKWSHMNVVVDDDTAVQPLVAV----LIDSGDTYYFGGCLGNSSGSGCKSPL-- 507
             V F       ++ V+  +   P +A     ++D     Y GG      G     PL  
Sbjct: 558 CHVDFQRDGRKGSISVNSRST--PFLATGDSEILDLESELYLGGL---PEGGRVDLPLPP 612

Query: 508 --------GGFQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDRCLPSYCE 557
                    G+ GC+R + I  ++ D   +   QGA+G        S     +C  + C 
Sbjct: 613 EVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGV---APFCSRETLKQCASAPCR 669

Query: 558 HGGECSQSWDTFSCDCLGTGYTGETC 583
           +GG C + W+ F CDC+GTG+ G  C
Sbjct: 670 NGGVCREGWNRFICDCIGTGFLGRVC 695



 Score =  118 bits (295), Expect = 4e-26
 Identities = 112/415 (26%), Positives = 173/415 (41%), Gaps = 23/415 (5%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F + ++ G+++    +   + + LE
Sbjct: 695  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 753

Query: 236  LIKGKLVFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHF 295
            L  G++   +N G         P TL  G  L+D  WH+V +      +  +VD  T   
Sbjct: 754  LDGGQMKLTVNLGKG-------PETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEG 806

Query: 296  QAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQIL 355
            Q  G  +++ L F     GI++  R  +    +F G L  L +NG    +  K       
Sbjct: 807  QMAG--AHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDITYC 864

Query: 356  MMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRG 415
             + N  F        PVTF S  SYLAL        + + FQF+T    G LLF     G
Sbjct: 865  EL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS-GNG 922

Query: 416  SGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVV-VDDD 472
            +   V+ L  G +   +F  G  P  +   +   +ND QWH+V  S    +++ + +D  
Sbjct: 923  NDFIVIELVKGYIHY-VFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSR 981

Query: 473  TAVQPLVAVL-IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVDPILV 529
            T  Q       +D     Y GG   N   +  K  +   GFQGCL  + +  +  D I  
Sbjct: 982  TVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIA- 1040

Query: 530  QQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
               AL     ++    G +  C    C + G C Q WD F+CDC  T Y G  C+
Sbjct: 1041 --DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN 1093



 Score =  111 bits (278), Expect = 4e-24
 Identities = 99/345 (28%), Positives = 159/345 (46%), Gaps = 43/345 (12%)

Query: 796  SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 854
            +F + +SYL         +  + F FKTT   G+ + N G   DFI IEL     + + F
Sbjct: 881  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIEL-VKGYIHYVF 939

Query: 855  DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 914
            D+GNGP  +   S  P NDNQWH+V   R+    ++   ++  +     ++G   L L  
Sbjct: 940  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 997

Query: 915  QLFIGGTA-----------TRQRGFLGCIRSLQLNGVALDLEERATVTPG-VEPGCAGHC 962
            +L+IGG +             + GF GC+ S+ LNG   DL   A    G VE GC G  
Sbjct: 998  ELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPS 1057

Query: 963  ST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAY-FATGSSMTYHFQEHYTL 1020
            +T     C N G C ++  G TCDC  ++Y GP C++  + Y F  G ++       YT 
Sbjct: 1058 TTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYTW 1112

Query: 1021 SENSSSLVSSLYRDVTLTR-EMITLSFRTTRSPSLLLYV--SSFYEEYLSVILANNGSLQ 1077
              N          D   TR + + + F T +  ++L+ V  +S   +YL + + + G++ 
Sbjct: 1113 PPN----------DRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVG 1161

Query: 1078 IRYKLDRHQNPDAFTFDFKN--MADGQLHQVKINREEAVVMVEVN 1120
            + + +      D  T D  N  ++DG+ H V+  R      ++V+
Sbjct: 1162 VIFNV----GTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202



 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 81/370 (21%), Positives = 152/370 (41%), Gaps = 63/370 (17%)

Query: 788  DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI----------- 836
            D +  +  +F +  +++  P +  + T  +   F+TT  +G+ + + G            
Sbjct: 457  DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSS 516

Query: 837  ---TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD 893
                D+  +EL     +    D+G+G  ++   S    ND +W HV  +R+ +  S+ V+
Sbjct: 517  AQRADYFAMEL-LDGHLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDFQRDGRKGSISVN 574

Query: 894  QLPQKMQPAPADGHVR-LQLNSQLFIGG----------------TATRQRGFLGCIRSLQ 936
                +  P  A G    L L S+L++GG                TA  + G++GC+R L 
Sbjct: 575  S---RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLF 631

Query: 937  LNGVALDLEERATV--TPGVEPGCAGH----CSTYGHLCRNGGRCREKRRGVTCDCAFSA 990
            ++G + DL   A      GV P C+      C++    CRNGG CRE      CDC  + 
Sbjct: 632  IDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAP--CRNGGVCREGWNRFICDCIGTG 689

Query: 991  YDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTR 1050
            + G  C  E +     GS                  L ++++ +     E ++L F + R
Sbjct: 690  FLGRVCEREATVLSYDGSMYM------------KIMLPNAMHTEA----EDVSLRFMSQR 733

Query: 1051 SPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINR 1110
            +  L++  +S   E    +       Q++  ++  + P+   F    + D + H V++ R
Sbjct: 734  AYGLMMATTS--RESADTLRLELDGGQMKLTVNLGKGPETL-FAGHKLNDNEWHTVRVVR 790

Query: 1111 EEAVVMVEVN 1120
                + + V+
Sbjct: 791  RGKSLQLSVD 800



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 57/218 (26%), Positives = 86/218 (39%), Gaps = 36/218 (16%)

Query: 864  TVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGG--- 920
            T+Q  TP  D++WH V   R+ +  +L VD   +            +Q+ S LF+GG   
Sbjct: 100  TLQLDTPVADDRWHMVLLTRDARRTALAVD--GEARAAEVRSKRREMQVASDLFVGGIPP 157

Query: 921  ----------TATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGH-----CSTY 965
                      T   +  F G + +L+L        ER     G + G  G      C+  
Sbjct: 158  DVRLSALTLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPA 209

Query: 966  GHLCRNGGRCREKRRG-VTCDCAFSAYDGPFCSNEI-----SAYFATGSSMTYHFQEHYT 1019
             + C NGG C     G V CDC+ + + G FCS E       A+    S     F    T
Sbjct: 210  RNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEGKEEFVA--T 267

Query: 1020 LSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLY 1057
               N        +  +  + + ITL+FRT +   L+L+
Sbjct: 268  FKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLH 305



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 84/381 (22%), Positives = 138/381 (36%), Gaps = 71/381 (18%)

Query: 808  AFHGELTADVCFFFKTTVSSGVFMENLG--ITDFIRIELRAPTEVTFSFDVGNGPCEVTV 865
            A H E   DV   F +  + G+ M        D +R+EL    ++  + ++G GP   T+
Sbjct: 717  AMHTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGG-QMKLTVNLGKGP--ETL 772

Query: 866  QSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQ 925
             +    NDN+WH VR  R  K   L VD +  + Q A A  H+RL+ ++     G  T +
Sbjct: 773  FAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IETGIMTER 828

Query: 926  R-------GFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREK 978
            R        F+G +  L  NG                         Y   C++G      
Sbjct: 829  RFISVVPSNFIGHLSGLVFNG-----------------------QPYMDQCKDG------ 859

Query: 979  RRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLT 1038
                         D  +C  E++A F   + +     +  T    SS L  +  +     
Sbjct: 860  -------------DITYC--ELNARFGLRAIVA----DPVTFKSRSSYLALATLQ--AYA 898

Query: 1039 REMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDF-KN 1097
               +   F+TT    LLL+ S    +++ + L       I Y  D    P     +  K 
Sbjct: 899  SMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMKGNSDKP 955

Query: 1098 MADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTR 1157
            + D Q H V ++R+   V      S       +     +    L +G + +   ++    
Sbjct: 956  VNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKL 1015

Query: 1158 RAATSGFTGCLSAVRFGRAAP 1178
             A+  GF GCL++V      P
Sbjct: 1016 VASRDGFQGCLASVDLNGRLP 1036



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 814 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFN 872
           T ++   F+T   +G+ +      D++ + L++   V    ++G+G  E  V+     FN
Sbjct: 287 TDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFN 345

Query: 873 DNQWHHVRAERNVK 886
           DN WH VR  RN++
Sbjct: 346 DNAWHDVRVTRNLR 359



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 45/175 (25%), Positives = 74/175 (42%), Gaps = 21/175 (12%)

Query: 1042 ITLSFRTTRSPSLLLYVSSFYE-EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 1100
            ++ S RT  + +LLLY+    + ++L ++L + G L++R+ L   + P     D   +AD
Sbjct: 53   LSFSLRTNATRALLLYLDDGGDCDFLELLLVD-GRLRLRFTLSCAE-PATLQLDTP-VAD 109

Query: 1101 GQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAA 1160
             + H V + R+     + V+  A+   + S   E      L +G      G  PD R +A
Sbjct: 110  DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVG------GIPPDVRLSA 163

Query: 1161 TS--------GFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMAR-CAAG 1206
             +         F G L+ ++ G   P  A L   G    T     AP    CA G
Sbjct: 164  LTLSTVKYEPPFRGLLANLKLGERPP--ALLGSQGLRGATADPLCAPARNPCANG 216



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 34/109 (31%), Positives = 53/109 (48%), Gaps = 9/109 (8%)

Query: 835  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPF-NDNQWHHVRAERNVKGASLQVD 893
            G+ D++++ +   T V   F+VG    ++T+  P    +D ++H VR  R+   A+LQVD
Sbjct: 1146 GLGDYLQLHIDQGT-VGVIFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1202

Query: 894  QLP-QKMQPAPADGHVRLQLNSQLFIG-GTATRQRGFLGCIRSLQLNGV 940
              P  +  PA   G      NSQ  I  G   + R F G +  L  NG+
Sbjct: 1203 SWPVNERYPA---GRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYNGL 1248



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 48/219 (21%), Positives = 81/219 (36%), Gaps = 23/219 (10%)

Query: 386 NSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAG 445
           +SGE    ++F  RT      LL+ +         L L DG+L+L    +   P  +   
Sbjct: 49  SSGE----LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLD 104

Query: 446 AGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGC 503
             + D +WH V  +       + VD +     + +    +      + GG   +   S  
Sbjct: 105 TPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSAL 164

Query: 504 KSPL----GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY--CE 557
                     F+G L  + +G++    +L  QG  G+  D           C P+   C 
Sbjct: 165 TLSTVKYEPPFRGLLANLKLGERP-PALLGSQGLRGATAD---------PLCAPARNPCA 214

Query: 558 HGGECSQ-SWDTFSCDCLGTGYTGETCHSSLYEQSCEAH 595
           +GG C+  +     CDC  TG+ G+ C    +     AH
Sbjct: 215 NGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAH 253



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 9/105 (8%)

Query: 241 LVFFLNSGNAKLPSTIA---PVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQA 297
           L   L  G  +L  T++   P TL L + + D  WH VL+     +    VD      + 
Sbjct: 78  LELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEV 137

Query: 298 KGDSSNLDLNFEISFGGILSPGRSRAFTRKS------FHGCLENL 336
           +     + +  ++  GGI    R  A T  +      F G L NL
Sbjct: 138 RSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANL 182


>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
          Length = 1712

 Score =  135 bits (339), Expect = 3e-31
 Identities = 120/453 (26%), Positives = 192/453 (42%), Gaps = 67/453 (14%)

Query: 183 VVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHGNHITLELIKGKLV 242
           V  F G     Y L   P++   D I+L F+ +Q NG++LH  G+  +++ L L  G + 
Sbjct: 289 VATFKGNEFFCYDLSHNPIQSSTDEITLAFRTLQRNGLMLHT-GKSADYVNLSLKSGAVW 347

Query: 243 FFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSV---------------LIELLDTQVNFT 287
             +N G+    + + PV        +D  WH V               ++  L   V  +
Sbjct: 348 LVINLGSGAFEALVEPVN----GKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTIS 403

Query: 288 VDKH-THHFQAKGDSSNLDLNFEISFGGILSPGRSR---AFTRKSFHGCLENLYYNGVD- 342
           VD   T     + D + L  +     GG  SP  +    +    +F GCL+++ Y   D 
Sbjct: 404 VDGILTTTGYTQEDYTMLGSDDFFYIGG--SPNTADLPGSPVSNNFMGCLKDVVYKNNDF 461

Query: 343 ---VTELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLALPGNSGEDKVSVTFQF 398
              ++ LAK+  P++ + G++SF C     + PVTF S  +++ALP  S +   S++  F
Sbjct: 462 KLELSRLAKEGDPKMKLQGDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDF 521

Query: 399 RTWNRAGHLLFGELQRGSGS------------FVLFLKDGKLKLSLFQAGQSPRNVTAGA 446
           RT    G LLF + +R  G             F + L DG L L L       +   +  
Sbjct: 522 RTTEPNGLLLFSQGRRAGGGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSR 581

Query: 447 GLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAV----LIDSGDTYYFGGCLGNSSGSG 502
            +NDG+W  V F       ++ V+  +   P +A     ++D     Y GG      G  
Sbjct: 582 KVNDGEWCHVDFQRDGRKGSISVNSRST--PFLATGDSEILDLESELYLGGL---PEGGR 636

Query: 503 CKSPL----------GGFQGCLRLITIGDKAVD--PILVQQGALGSFRDLQIDSCGITDR 550
              PL           G+ GC+R + I  ++ D   +   QGA+G        S     +
Sbjct: 637 VDLPLPPEVWTAALRAGYVGCVRDLFIDGRSRDLRGLAEAQGAVGV---APFCSRETLKQ 693

Query: 551 CLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
           C  + C +GG C + W+ F CDC+GTG+ G  C
Sbjct: 694 CASAPCRNGGVCREGWNRFICDCIGTGFLGRVC 726



 Score =  115 bits (289), Expect = 2e-25
 Identities = 113/418 (27%), Positives = 176/418 (42%), Gaps = 20/418 (4%)

Query: 177  CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
            C  ++ V+ +DG   +   L         DV SL+F + ++ G+++    +   + + LE
Sbjct: 726  CEREATVLSYDGSMYMKIMLPNAMHTEAEDV-SLRFMSQRAYGLMMATTSRESADTLRLE 784

Query: 236  LIKGKLVFFLNSGNAKL---PSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHT 292
            L  G++   +N    ++   PS   P TL  G  L+D  WH+V +      +  +VD  T
Sbjct: 785  LDGGQMKLTVNLDCLRVGCAPSK-GPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVT 843

Query: 293  HHFQAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKP 352
               Q  G  +++ L F     GI++  R  +    +F G L  L +NG    +  K    
Sbjct: 844  VEGQMAG--AHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQCKDGDI 901

Query: 353  QILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGEL 412
                + N  F        PVTF S  SYLAL        + + FQF+T    G LLF   
Sbjct: 902  TYCEL-NARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNS- 959

Query: 413  QRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVV-V 469
              G+   V+ L  G +   +F  G  P  +   +   +ND QWH+V  S    +++ + +
Sbjct: 960  GNGNDFIVIELVKGYIHY-VFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTLKI 1018

Query: 470  DDDTAVQPLVAVL-IDSGDTYYFGGCLGNSSGSGCK--SPLGGFQGCLRLITIGDKAVDP 526
            D  T  Q       +D     Y GG   N   +  K  +   GFQGCL  + +  +  D 
Sbjct: 1019 DSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDL 1078

Query: 527  ILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
            I     AL     ++    G +  C    C + G C Q WD F+CDC  T Y G  C+
Sbjct: 1079 IA---DALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCN 1133



 Score =  111 bits (278), Expect = 4e-24
 Identities = 99/345 (28%), Positives = 159/345 (46%), Gaps = 43/345 (12%)

Query: 796  SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 854
            +F + +SYL         +  + F FKTT   G+ + N G   DFI IEL     + + F
Sbjct: 921  TFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIEL-VKGYIHYVF 979

Query: 855  DVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNS 914
            D+GNGP  +   S  P NDNQWH+V   R+    ++   ++  +     ++G   L L  
Sbjct: 980  DLGNGPSLMKGNSDKPVNDNQWHNVVVSRD--PGNVHTLKIDSRTVTQHSNGARNLDLKG 1037

Query: 915  QLFIGGTA-----------TRQRGFLGCIRSLQLNGVALDLEERATVTPG-VEPGCAGHC 962
            +L+IGG +             + GF GC+ S+ LNG   DL   A    G VE GC G  
Sbjct: 1038 ELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLPDLIADALHRIGQVERGCDGPS 1097

Query: 963  ST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAY-FATGSSMTYHFQEHYTL 1020
            +T     C N G C ++  G TCDC  ++Y GP C++  + Y F  G ++       YT 
Sbjct: 1098 TTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPGTTYIFGKGGALI-----TYTW 1152

Query: 1021 SENSSSLVSSLYRDVTLTR-EMITLSFRTTRSPSLLLYV--SSFYEEYLSVILANNGSLQ 1077
              N          D   TR + + + F T +  ++L+ V  +S   +YL + + + G++ 
Sbjct: 1153 PPN----------DRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI-DQGTVG 1201

Query: 1078 IRYKLDRHQNPDAFTFDFKN--MADGQLHQVKINREEAVVMVEVN 1120
            + + +      D  T D  N  ++DG+ H V+  R      ++V+
Sbjct: 1202 VIFNV----GTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242



 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 65/258 (25%), Positives = 110/258 (42%), Gaps = 44/258 (17%)

Query: 788  DKSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI----------- 836
            D +  +  +F +  +++  P +  + T  +   F+TT  +G+ + + G            
Sbjct: 488  DVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAGGGAGSHSS 547

Query: 837  ---TDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVD 893
                D+  +EL     +    D+G+G  ++   S    ND +W HV  +R+ +  S+ V+
Sbjct: 548  AQRADYFAMEL-LDGHLYLLLDMGSGGIKLRASS-RKVNDGEWCHVDFQRDGRKGSISVN 605

Query: 894  QLPQKMQPAPADGHVR-LQLNSQLFIGG----------------TATRQRGFLGCIRSLQ 936
                +  P  A G    L L S+L++GG                TA  + G++GC+R L 
Sbjct: 606  S---RSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVRDLF 662

Query: 937  LNGVALDLEERATV--TPGVEPGCAGH----CSTYGHLCRNGGRCREKRRGVTCDCAFSA 990
            ++G + DL   A      GV P C+      C++    CRNGG CRE      CDC  + 
Sbjct: 663  IDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAP--CRNGGVCREGWNRFICDCIGTG 720

Query: 991  YDGPFCSNEISAYFATGS 1008
            + G  C  E +     GS
Sbjct: 721  FLGRVCEREATVLSYDGS 738



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 44/155 (28%), Positives = 64/155 (41%), Gaps = 29/155 (18%)

Query: 864 TVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGG--- 920
           T+Q  TP  D++WH V   R+ +  +L VD   +            +Q+ S LF+GG   
Sbjct: 100 TLQLDTPVADDRWHMVLLTRDARRTALAVD--GEARAAEVRSKRREMQVASDLFVGGIPP 157

Query: 921 ----------TATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGH-----CSTY 965
                     T   +  F G + +L+L        ER     G + G  G      C+  
Sbjct: 158 DVRLSALTLSTVKYEPPFRGLLANLKLG-------ERPPALLGSQ-GLRGATADPLCAPA 209

Query: 966 GHLCRNGGRCREKRRG-VTCDCAFSAYDGPFCSNE 999
            + C NGG C     G V CDC+ + + G FCS E
Sbjct: 210 RNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCSEE 244



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 86/387 (22%), Positives = 139/387 (35%), Gaps = 74/387 (19%)

Query: 808  AFHGELTADVCFFFKTTVSSGVFMENLG--ITDFIRIELRA-PTEVTFSFD---VGNGPC 861
            A H E   DV   F +  + G+ M        D +R+EL     ++T + D   VG  P 
Sbjct: 748  AMHTE-AEDVSLRFMSQRAYGLMMATTSRESADTLRLELDGGQMKLTVNLDCLRVGCAPS 806

Query: 862  E--VTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIG 919
            +   T+ +    NDN+WH VR  R  K   L VD +  + Q A A  H+RL+ ++     
Sbjct: 807  KGPETLFAGHKLNDNEWHTVRVVRRGKSLQLSVDNVTVEGQMAGA--HMRLEFHN--IET 862

Query: 920  GTATRQR-------GFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNG 972
            G  T +R        F+G +  L  NG                         Y   C++G
Sbjct: 863  GIMTERRFISVVPSNFIGHLSGLVFNG-----------------------QPYMDQCKDG 899

Query: 973  GRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLY 1032
                               D  +C  E++A F   + +     +  T    SS L  +  
Sbjct: 900  -------------------DITYC--ELNARFGLRAIVA----DPVTFKSRSSYLALATL 934

Query: 1033 RDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFT 1092
            +        +   F+TT    LLL+ S    +++ + L       I Y  D    P    
Sbjct: 935  Q--AYASMHLFFQFKTTAPDGLLLFNSGNGNDFIVIELVKG---YIHYVFDLGNGPSLMK 989

Query: 1093 FDF-KNMADGQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG 1151
             +  K + D Q H V ++R+   V      S       +     +    L +G + +   
Sbjct: 990  GNSDKPVNDNQWHNVVVSRDPGNVHTLKIDSRTVTQHSNGARNLDLKGELYIGGLSKNMF 1049

Query: 1152 ADPDTRRAATSGFTGCLSAVRFGRAAP 1178
            ++     A+  GF GCL++V      P
Sbjct: 1050 SNLPKLVASRDGFQGCLASVDLNGRLP 1076



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 2/74 (2%)

Query: 814 TADVCFFFKTTVSSGVFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPT-PFN 872
           T ++   F+T   +G+ +      D++ + L++   V    ++G+G  E  V+     FN
Sbjct: 311 TDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGA-VWLVINLGSGAFEALVEPVNGKFN 369

Query: 873 DNQWHHVRAERNVK 886
           DN WH VR  RN++
Sbjct: 370 DNAWHDVRVTRNLR 383



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 45/175 (25%), Positives = 74/175 (42%), Gaps = 21/175 (12%)

Query: 1042 ITLSFRTTRSPSLLLYVSSFYE-EYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMAD 1100
            ++ S RT  + +LLLY+    + ++L ++L + G L++R+ L   + P     D   +AD
Sbjct: 53   LSFSLRTNATRALLLYLDDGGDCDFLELLLVD-GRLRLRFTLSCAE-PATLQLDTP-VAD 109

Query: 1101 GQLHQVKINREEAVVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAA 1160
             + H V + R+     + V+  A+   + S   E      L +G      G  PD R +A
Sbjct: 110  DRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVG------GIPPDVRLSA 163

Query: 1161 TS--------GFTGCLSAVRFGRAAPLKAALRPSGPSRVTVRGHVAPMAR-CAAG 1206
             +         F G L+ ++ G   P  A L   G    T     AP    CA G
Sbjct: 164  LTLSTVKYEPPFRGLLANLKLGERPP--ALLGSQGLRGATADPLCAPARNPCANG 216



 Score = 37.4 bits (85), Expect = 0.093
 Identities = 51/237 (21%), Positives = 86/237 (36%), Gaps = 23/237 (9%)

Query: 386 NSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAG 445
           +SGE    ++F  RT      LL+ +         L L DG+L+L    +   P  +   
Sbjct: 49  SSGE----LSFSLRTNATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLD 104

Query: 446 AGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAVL--IDSGDTYYFGGCLGNSSGSGC 503
             + D +WH V  +       + VD +     + +    +      + GG   +   S  
Sbjct: 105 TPVADDRWHMVLLTRDARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSAL 164

Query: 504 KSPL----GGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSY--CE 557
                     F+G L  + +G++    +L  QG  G+  D           C P+   C 
Sbjct: 165 TLSTVKYEPPFRGLLANLKLGERP-PALLGSQGLRGATAD---------PLCAPARNPCA 214

Query: 558 HGGECSQ-SWDTFSCDCLGTGYTGETCHSSLYEQSCEAHKHRGNPSGLYYIDADGSG 613
           +GG C+  +     CDC  TG+ G+ C    +     AH    +  G       G+G
Sbjct: 215 NGGLCTVLAPGEVGCDCSHTGFGGKFCSEEEHPMEGPAHLTLNSEVGSLLFSEGGAG 271



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 27/105 (25%), Positives = 41/105 (39%), Gaps = 9/105 (8%)

Query: 241 LVFFLNSGNAKLPSTIA---PVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQA 297
           L   L  G  +L  T++   P TL L + + D  WH VL+     +    VD      + 
Sbjct: 78  LELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRDARRTALAVDGEARAAEV 137

Query: 298 KGDSSNLDLNFEISFGGILSPGRSRAFTRKS------FHGCLENL 336
           +     + +  ++  GGI    R  A T  +      F G L NL
Sbjct: 138 RSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLANL 182



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 835  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPF-NDNQWHHVRAERNVKGASLQVD 893
            G+ D++++ +   T V   F+VG    ++T+  P    +D ++H VR  R+   A+LQVD
Sbjct: 1186 GLGDYLQLHIDQGT-VGVIFNVGTD--DITIDEPNAIVSDGKYHVVRFTRSGGNATLQVD 1242

Query: 894  QLP-QKMQPAPADGHVRLQLNSQ 915
              P  +  PA    + RL +  Q
Sbjct: 1243 SWPVNERYPAGNFDNERLAIARQ 1265


>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
          Length = 1061

 Score =  117 bits (292), Expect = 9e-26
 Identities = 109/418 (26%), Positives = 179/418 (42%), Gaps = 20/418 (4%)

Query: 177 CAYKSEVVYFDGQSALLYTLDKKPLKPIRDVISLKFKAMQSNGILLHREGQHG-NHITLE 235
           C  ++ ++ +DG   +   +         DV S +F + ++ G+L+    +   + + LE
Sbjct: 306 CEREASILSYDGSMYMKIIMPMVMHTEAEDV-SFRFMSQRAYGLLVATTSRDSADTLRLE 364

Query: 236 LIKGKLVFFLNSGNAKLP--STIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTH 293
           L  G++   +N    ++   S+  P TL  G  L+D  WH+V +      +  TVD    
Sbjct: 365 LDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVA 424

Query: 294 HFQAKGDSSNLDL-NFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKP 352
                GD + L+  N E    GI++  R  +    SF G L++L +NG+   +L K    
Sbjct: 425 EGTMVGDHTRLEFHNIET---GIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDI 481

Query: 353 QILMMGNVSFSCPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGEL 412
               +    F        PVTF +  SYL+L        + + FQF+T +  G +LF   
Sbjct: 482 DYCEL-KARFGLRNIIADPVTFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSG 540

Query: 413 QRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAG--LNDGQWHSVSFSAKWSHMNVVVD 470
             G+    + L  G +   +F  G  P  +   +   LND QWH+V  +   S+ + +  
Sbjct: 541 D-GNDFIAVELVKGYIHY-VFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKV 598

Query: 471 DDTAVQPLV--AVLID-SGDTYYFGGCLGNSSG-SGCKSPLGGFQGCLRLITIGDKAVDP 526
           D   V  ++  A  +D  GD Y  G   G  S      +   GFQGCL  + +  +  D 
Sbjct: 599 DTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDL 658

Query: 527 ILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETCH 584
           I     AL     ++    G +  C    C + G C Q W+ F+CDC  T Y+G  C+
Sbjct: 659 I---NDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCN 713



 Score =  110 bits (276), Expect = 7e-24
 Identities = 99/345 (28%), Positives = 150/345 (43%), Gaps = 43/345 (12%)

Query: 796  SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI-TDFIRIELRAPTEVTFSF 854
            +F T++SYL         +  + F FKTT   G  + N G   DFI +EL     + + F
Sbjct: 501  TFKTKSSYLSLATLQAYTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVEL-VKGYIHYVF 559

Query: 855  DVGNGPCEVTVQSPTPFNDNQWHHVRAER-NVKGASLQVDQLPQKMQPAPADGHVRLQLN 913
            D+GNGP  +   S  P NDNQWH+V   R N    SL+VD    K+     +G   L L 
Sbjct: 560  DLGNGPNVIKGNSDRPLNDNQWHNVVITRDNSNTHSLKVD---TKVVTQVINGAKNLDLK 616

Query: 914  SQLFIGGTA-----------TRQRGFLGCIRSLQLNGVALDLEERATVTPG-VEPGCAGH 961
              L++ G A             + GF GC+ S+ LNG   DL   A    G +E GC G 
Sbjct: 617  GDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGP 676

Query: 962  CST-YGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYF--ATGSSMTYHFQEHY 1018
             +T     C N G C ++  G TCDC+ ++Y G  C++  + Y    +G  + Y +  + 
Sbjct: 677  STTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPAND 736

Query: 1019 TLSENSSSLV---SSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGS 1075
              S  S  L    S+  +D  L         R   +P L  ++    E+    ++ N G+
Sbjct: 737  RPSTRSDRLAVGFSTTVKDGILV--------RIDSAPGLGDFLQLHIEQGKIGVVFNIGT 788

Query: 1076 LQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVN 1120
            + I  K +R             + DG+ H V+  R      ++V+
Sbjct: 789  VDISIKEER-----------TPVNDGKYHVVRFTRNGGNATLQVD 822



 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 75/286 (26%), Positives = 121/286 (42%), Gaps = 36/286 (12%)

Query: 328 SFHGCLENLYYNGVDV----TELAKKHKPQILMMGNVSFSCPQPQTV-PVTFLSSRSYLA 382
           +F GCL+ + Y   D+    + LA+    ++ + G V F C    T+ P+ F +  +Y++
Sbjct: 27  NFMGCLKEVVYKNNDIRLELSRLARIADTKMKIYGEVVFKCENVATLDPINFETPEAYIS 86

Query: 383 LPGNSGEDKVSVTFQFRTWNRAGHLLF--GELQRGSGS----------FVLFLKDGKLKL 430
           LP  + +   S++F FRT    G +LF  G+ Q    +          F + L DG L L
Sbjct: 87  LPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYL 146

Query: 431 SLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLVAV----LIDSG 486
            L     + +        NDG+W+ V          + V+      P  A     ++D  
Sbjct: 147 LLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRT--PFTASGESEILDLE 204

Query: 487 DTYYFGGCLGNSSGSGCKSPLG------GFQGCLRLITIG--DKAVDPILVQQGALGSFR 538
              Y GG   N +G    + L       G+ GC+R + I    K +  +   Q A G   
Sbjct: 205 GDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAG--- 261

Query: 539 DLQIDSCGITDRCLPSY-CEHGGECSQSWDTFSCDCLGTGYTGETC 583
            ++     ++ +   SY C++   C   W+ F CDC GTGY G TC
Sbjct: 262 -VKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTC 306



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 61/249 (24%), Positives = 104/249 (41%), Gaps = 43/249 (17%)

Query: 796  SFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGI--------------TDFIR 841
            +F T  +Y+  P ++ +    + F F+TT  +G+ +   G                DF  
Sbjct: 77   NFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFA 136

Query: 842  IELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQP 901
            +EL     +    D+G+G  +V        ND +W+HV  +R+ +  ++ V+    +  P
Sbjct: 137  VEL-LDGNLYLLLDMGSGTIKVKATQKKA-NDGEWYHVDIQRDGRSGTISVNS---RRTP 191

Query: 902  APADGHVR-LQLNSQLFIGG---------------TATRQRGFLGCIRSLQLNGVALDLE 945
              A G    L L   +++GG               TA    G++GCIR L ++G + ++ 
Sbjct: 192  FTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIR 251

Query: 946  ERATV--TPGVEPGC----AGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNE 999
            + A +    GV+  C    A  C +Y   C+N   C++      CDC  + Y G  C  E
Sbjct: 252  QLAEMQNAAGVKSSCSRMSAKQCDSYP--CKNNAVCKDGWNRFICDCTGTGYWGRTCERE 309

Query: 1000 ISAYFATGS 1008
             S     GS
Sbjct: 310  ASILSYDGS 318



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 71/340 (20%), Positives = 123/340 (36%), Gaps = 76/340 (22%)

Query: 208 ISLKFKAMQSNGILLHREGQHGNH-------------ITLELIKGKLVFFLN--SGNAKL 252
           IS  F+  + NG++L   G+                   +EL+ G L   L+  SG  K+
Sbjct: 98  ISFDFRTTEPNGLILFTHGKPQERKDARSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKV 157

Query: 253 PSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTHHFQAKGDSSNLDLNFEISF 312
            +T            +D  W+ V I+        +V+     F A G+S  LDL  ++  
Sbjct: 158 KATQKKA--------NDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYL 209

Query: 313 GG--------ILSPGRSRAFTRKSFHGCLENLYYNG--VDVTELAKKHKPQILMMGNVSF 362
           GG        IL      A     + GC+ +L+ +G   ++ +LA+      +       
Sbjct: 210 GGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRM 269

Query: 363 SCPQPQTVPV-----------TFLSSRSYLALPGNSGEDKVS------------------ 393
           S  Q  + P             F+   +     G + E + S                  
Sbjct: 270 SAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKIIMPMVM 329

Query: 394 ------VTFQFRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSL--------FQAGQSP 439
                 V+F+F +    G L+    +  + +  L L  G++KL +          + + P
Sbjct: 330 HTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGP 389

Query: 440 RNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAVQPLV 479
             + AG  LND +WH+V    +   + + VDDD A   +V
Sbjct: 390 ETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMV 429



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 86/357 (24%), Positives = 128/357 (35%), Gaps = 84/357 (23%)

Query: 864  TVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTAT 923
            T+ +    NDN+WH VR  R  K   L VD      +      H RL+ ++     G  T
Sbjct: 391  TLYAGQKLNDNEWHTVRVVRRGKSLKLTVDD--DVAEGTMVGDHTRLEFHN--IETGIMT 446

Query: 924  RQR-------GFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCR 976
             +R        F+G ++SL  NG+                        Y  LC+NG    
Sbjct: 447  EKRYISVVPSSFIGHLQSLMFNGL-----------------------LYIDLCKNG---- 479

Query: 977  EKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVT 1036
                           D  +C  E+ A F   + +     +  T    SS L  SL     
Sbjct: 480  ---------------DIDYC--ELKARFGLRNIIA----DPVTFKTKSSYL--SLATLQA 516

Query: 1037 LTREMITLSFRTTRSPSLLLYVSSFYEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDF- 1095
             T   +   F+TT     +L+ S    ++++V L       I Y  D    P+    +  
Sbjct: 517  YTSMHLFFQFKTTSPDGFILFNSGDGNDFIAVELVKG---YIHYVFDLGNGPNVIKGNSD 573

Query: 1096 KNMADGQLHQVKINREEA-VVMVEVNQSAKKQVILSSGTEFNAVKSLILGKVLEAAG--- 1151
            + + D Q H V I R+ +    ++V+     QVI       N  K+L L   L  AG   
Sbjct: 574  RPLNDNQWHNVVITRDNSNTHSLKVDTKVVTQVI-------NGAKNLDLKGDLYMAGLAQ 626

Query: 1152 ---ADPDTRRAATSGFTGCLSAVRFGRAAP--LKAALRPSGPSRVTVRGHVAPMARC 1203
               ++     A+  GF GCL++V      P  +  AL  SG      RG   P   C
Sbjct: 627  GMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIE---RGCEGPSTTC 680



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 6/123 (4%)

Query: 821 FKTTVSSGVFME---NLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWH 877
           F TTV  G+ +      G+ DF+++ +    ++   F++G     +  +  TP ND ++H
Sbjct: 749 FSTTVKDGILVRIDSAPGLGDFLQLHIEQG-KIGVVFNIGTVDISIK-EERTPVNDGKYH 806

Query: 878 HVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQL 937
            VR  RN   A+LQVD  P                 +Q+ IGG   + R F G +  L  
Sbjct: 807 VVRFTRNGGNATLQVDNWPVNEHYPTGRQLTIFNTQAQIAIGG-KDKGRLFQGQLSGLYY 865

Query: 938 NGV 940
           +G+
Sbjct: 866 DGL 868



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 47/202 (23%), Positives = 80/202 (39%), Gaps = 25/202 (12%)

Query: 185 YFDGQSA--LLYTLDKKPLKPIR-DVISLKFKAMQSNGILLHREGQHG--NHITLELIKG 239
           Y  G+S   +LYT         R D +++ F     +GIL+  +   G  + + L + +G
Sbjct: 719 YIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQG 778

Query: 240 KL--VFFLNSGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKH--THHF 295
           K+  VF + + +  +     PV        +D  +H V            VD      H+
Sbjct: 779 KIGVVFNIGTVDISIKEERTPV--------NDGKYHVVRFTRNGGNATLQVDNWPVNEHY 830

Query: 296 QAKGDSSNLDLNFEISFGGILSPGRSRAFTRKSFHGCLENLYYNGVDVTELAKKHKPQIL 355
                 +  +   +I+ GG    GR        F G L  LYY+G+ V  +A ++ P I 
Sbjct: 831 PTGRQLTIFNTQAQIAIGG-KDKGRL-------FQGQLSGLYYDGLKVLNMAAENNPNIK 882

Query: 356 MMGNVSFSCPQPQTVPVTFLSS 377
           + G+V      P  +  T  +S
Sbjct: 883 INGSVRLVGEVPSILGTTQTTS 904


>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
           sapiens]
          Length = 387

 Score = 90.1 bits (222), Expect = 1e-17
 Identities = 54/160 (33%), Positives = 84/160 (52%), Gaps = 15/160 (9%)

Query: 31  CDSPLA---SALPRSSFSSSSELSS------SHGPGFSRLNRRDGAGGWTPLVSNKYQWL 81
           C +PL    +++P    ++SS   +      S  P ++RL+++     W        QWL
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289

Query: 82  QIDLGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYR--REESIWGFPGNTN 137
           Q+DLG   EVT + TQG   +GS  +V SY + +S+   NW +Y+  R  S   FPGN +
Sbjct: 290 QVDLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWD 349

Query: 138 ADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             S      + P  AR++R LP+AW+   RI +R+E+ GC
Sbjct: 350 NHSHKKNLFETPILARYVRILPVAWH--NRIALRLELLGC 387



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 17  TQTWSPVGAGNPPDCDSPLASALPRSSFSSSSELSSSHG-PGFSRLNRRDGAGGWTPLVS 75
           T+   P+G  N    +S +A++  R +F     L   H  P  +RLNR      WTP  +
Sbjct: 68  TKCVEPLGLENGNIANSQIAASSVRVTF-----LGLQHWVPELARLNRAGMVNAWTPSSN 122

Query: 76  NKYQWLQIDLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNW-------KQYRRE 126
           +   W+Q++L  RM VT V TQG     S +++ ++ + +S  G  +       K+++  
Sbjct: 123 DDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKE- 181

Query: 127 ESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
                F GN N ++V     + P EA+++R  P + +      +R E+ GC
Sbjct: 182 -----FVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHT--ACTLRFELLGC 225


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 54/158 (34%), Positives = 79/158 (50%), Gaps = 13/158 (8%)

Query: 31   CDSPLA---SALPRSSFSSSSELSSSHG----PGFSRLNRRDGAGGWTPLVSNKYQWLQI 83
            C +PL      +     ++SS   S  G    P  +RLN +     W    +N  QWL+I
Sbjct: 2066 CSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEI 2125

Query: 84   DLGERMEVTAVATQG--GYGSSDWVTSYLLMFSDGGRNWKQYRREESIWG--FPGNTNAD 139
            DL +  ++TA+ TQG     S  +V SY + +S+ G  WK YR + S+    F GNTN  
Sbjct: 2126 DLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTNTK 2185

Query: 140  SVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
              V     PP  +RF+R +P  WN    I +R+E++GC
Sbjct: 2186 GHVKNFFNPPIISRFIRVIPKTWNQ--SIALRLELFGC 2221



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 43/159 (27%), Positives = 77/159 (48%), Gaps = 14/159 (8%)

Query: 30   DCDSP--LASALPRSSFSSSSELSSSHGPGFSRLNRRDGAGGWT--PLVSN--KYQWLQI 83
            DC  P  L++ +   S   +SE      P  +RLN       W+   L +      W+Q+
Sbjct: 1906 DCRMPMGLSTGIISDSQIKASEFLGYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQV 1965

Query: 84   DLGERMEVTAVATQGG--YGSSDWVTSYLLMFSDGGRNWKQYRREES--IWGFPGNTNAD 139
            D+ + + +T + TQG   Y  S + T + + +S    NW+ ++   +  +  F GN++A 
Sbjct: 1966 DMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDAS 2025

Query: 140  SVVHYRLQPPFEARFLRFLPL-AWNPRGRIGMRIEVYGC 177
            ++   +  PP  AR++R  P  A+N   R  +R+E+ GC
Sbjct: 2026 TIKENQFDPPIVARYIRISPTRAYN---RPTLRLELQGC 2061


>gi|62420886 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 12/199 (6%)

Query: 8   VLKVLLLLPTQTWSPVGAGNPPDCDSPLASA---LPRSSFSSSSELSSSHGPGFSRLNRR 64
           +L + LLLP  + S     NP  C  PL  +   +P    ++SS+ S S    + RL+  
Sbjct: 8   LLVLFLLLPILS-SAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSE 66

Query: 65  DGAGGWTPLV----SNKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLLMFSDGG 117
           +G G W P +     +  ++LQIDL     +T V TQG +      ++   Y + +S  G
Sbjct: 67  EGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG 126

Query: 118 RNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             W  +R         GN+N   +    L+PP  ARF+RF+P+  +    + MR+E+YGC
Sbjct: 127 TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVT-DHSMNVCMRVELYGC 185

Query: 178 AYKSEVVYFDGQSALLYTL 196
            +   +V ++  +   + L
Sbjct: 186 VWLDGLVSYNAPAGQQFVL 204


>gi|62420884 discoidin domain receptor family, member 2 precursor
           [Homo sapiens]
          Length = 855

 Score = 84.3 bits (207), Expect = 7e-16
 Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 12/199 (6%)

Query: 8   VLKVLLLLPTQTWSPVGAGNPPDCDSPLASA---LPRSSFSSSSELSSSHGPGFSRLNRR 64
           +L + LLLP  + S     NP  C  PL  +   +P    ++SS+ S S    + RL+  
Sbjct: 8   LLVLFLLLPILS-SAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSE 66

Query: 65  DGAGGWTPLV----SNKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLLMFSDGG 117
           +G G W P +     +  ++LQIDL     +T V TQG +      ++   Y + +S  G
Sbjct: 67  EGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDG 126

Query: 118 RNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRIGMRIEVYGC 177
             W  +R         GN+N   +    L+PP  ARF+RF+P+  +    + MR+E+YGC
Sbjct: 127 TRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVT-DHSMNVCMRVELYGC 185

Query: 178 AYKSEVVYFDGQSALLYTL 196
            +   +V ++  +   + L
Sbjct: 186 VWLDGLVSYNAPAGQQFVL 204


>gi|38327632 discoidin domain receptor family, member 1 isoform b
           [Homo sapiens]
          Length = 876

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 16/198 (8%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLAS---ALPRSSFSSSSELSSSHGPG 57
           M   A + L +LLL+ +      G  +P  C   L      +P S  S+SS  S S    
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 58  FSRLNRRDGAGGWTPLVS---NKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLL 111
            SRL   DG G W P  S    + ++LQ+DL     V  V TQG +      ++  SY L
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 112 MFSDGGRNWKQYRREESIWG---FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRI 168
            +S  GR W  ++     WG     GN + + VV   L PP  AR +RF P A      +
Sbjct: 121 RYSRDGRRWMGWKDR---WGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMS-V 176

Query: 169 GMRIEVYGCAYKSEVVYF 186
            +R+E+YGC ++  ++ +
Sbjct: 177 CLRVELYGCLWRDGLLSY 194


>gi|83977452 discoidin domain receptor family, member 1 isoform c
           [Homo sapiens]
          Length = 919

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 16/198 (8%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLAS---ALPRSSFSSSSELSSSHGPG 57
           M   A + L +LLL+ +      G  +P  C   L      +P S  S+SS  S S    
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 58  FSRLNRRDGAGGWTPLVS---NKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLL 111
            SRL   DG G W P  S    + ++LQ+DL     V  V TQG +      ++  SY L
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 112 MFSDGGRNWKQYRREESIWG---FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRI 168
            +S  GR W  ++     WG     GN + + VV   L PP  AR +RF P A      +
Sbjct: 121 RYSRDGRRWMGWKDR---WGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMS-V 176

Query: 169 GMRIEVYGCAYKSEVVYF 186
            +R+E+YGC ++  ++ +
Sbjct: 177 CLRVELYGCLWRDGLLSY 194


>gi|83977450 discoidin domain receptor family, member 1 isoform a
           [Homo sapiens]
          Length = 913

 Score = 79.0 bits (193), Expect = 3e-14
 Identities = 62/198 (31%), Positives = 91/198 (45%), Gaps = 16/198 (8%)

Query: 1   MASVAWAVLKVLLLLPTQTWSPVGAGNPPDCDSPLAS---ALPRSSFSSSSELSSSHGPG 57
           M   A + L +LLL+ +      G  +P  C   L      +P S  S+SS  S S    
Sbjct: 1   MGPEALSSLLLLLLVASGDADMKGHFDPAKCRYALGMQDRTIPDSDISASSSWSDSTAAR 60

Query: 58  FSRLNRRDGAGGWTPLVS---NKYQWLQIDLGERMEVTAVATQGGYGSS---DWVTSYLL 111
            SRL   DG G W P  S    + ++LQ+DL     V  V TQG +      ++  SY L
Sbjct: 61  HSRLESSDGDGAWCPAGSVFPKEEEYLQVDLQRLHLVALVGTQGRHAGGLGKEFSRSYRL 120

Query: 112 MFSDGGRNWKQYRREESIWG---FPGNTNADSVVHYRLQPPFEARFLRFLPLAWNPRGRI 168
            +S  GR W  ++     WG     GN + + VV   L PP  AR +RF P A      +
Sbjct: 121 RYSRDGRRWMGWKDR---WGQEVISGNEDPEGVVLKDLGPPMVARLVRFYPRADRVMS-V 176

Query: 169 GMRIEVYGCAYKSEVVYF 186
            +R+E+YGC ++  ++ +
Sbjct: 177 CLRVELYGCLWRDGLLSY 194


>gi|33469931 EGF-like, fibronectin type III and laminin G domains
            isoform 2 [Homo sapiens]
          Length = 775

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 100/384 (26%), Positives = 154/384 (40%), Gaps = 50/384 (13%)

Query: 803  YLHFPAFHGELTADVCFFFKTTVSSGVFMENL--GITDFIRIELRAPTEVTFSFDVGNGP 860
            YL F  F  E+T      F+     GV + +   G  DF+ I L A   V F FD G+G 
Sbjct: 397  YLSFMEF--EIT------FRPDSGDGVLLYSYDTGSKDFLSINL-AGGHVEFRFDCGSGT 447

Query: 861  CEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG-HVRLQLNSQLFIG 919
                ++S  P     WH +R  R  K   LQVD+  QK+    A+G   +++ N+ +FIG
Sbjct: 448  G--VLRSEDPLTLGNWHELRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIG 503

Query: 920  GTATRQ---------RGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCR 970
            G              + F G I+ + LN   + ++     T GV    A H       C 
Sbjct: 504  GVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKH--DFTSGVNVENAAHPCVRAP-CA 560

Query: 971  NGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSS 1030
            +GG CR ++ G  CDC    ++G  C   I         +       Y   +N   L   
Sbjct: 561  HGGSCRPRKEGYDCDCPL-GFEGLHCQKAI----IEAIEIPQFIGRSYLTYDNPDIL--- 612

Query: 1031 LYRDVTLTREMITLSFRTTRSPSLLLYVSSF----YEEYLSVILANNGSLQIRYKLDRHQ 1086
              + V+ +R  + + F+TT    LLL+          +++S+ L  +G+L   Y L    
Sbjct: 613  --KRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSGV 669

Query: 1087 NPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQ-SAKKQVILSSGTEFNAVKSLILGK 1145
                    F    DG+ H+VK  R+     + V+   A+         + N   +L +G 
Sbjct: 670  ASIMVNGSFN---DGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGG 726

Query: 1146 VLEAAGADPDTRRAATSGFTGCLS 1169
            + E A     T R    G  GC+S
Sbjct: 727  MKEIA---LHTNRQYMRGLVGCIS 747



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 95/433 (21%), Positives = 157/433 (36%), Gaps = 69/433 (15%)

Query: 208 ISLKFKAMQSNGILLH-REGQHG--NHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLG 264
           I+L+F+A   +G+LL+  E +HG  + ++L +I+  L F  N G   +   ++   + LG
Sbjct: 177 ITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTG-VAIIVSETKIKLG 235

Query: 265 SLLDDQHWHSVLIELLDTQVNFTVDKHTHHF-QAKGDSSNLDLNFEISFGGILSP-GRSR 322
                  WH+V++          ++  T    Q++G  S +     +  GG  S     R
Sbjct: 236 G------WHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVR 289

Query: 323 AF-TRKSFHGCLENLYYNG----------------VDVTELAKK--------HKPQILMM 357
           A  T + F GC+++L  NG                 DV E +          H      +
Sbjct: 290 ATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAI 349

Query: 358 GNVSFSCPQPQ-------------TVPVTFLSSRSYLALPGNSGEDKVSVTFQ-----FR 399
              S+ C  P              T+P    S RSY A P    E +  ++F      FR
Sbjct: 350 KADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPL-EPQHYLSFMEFEITFR 408

Query: 400 TWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFS 459
             +  G LL+     GS  F+     G      F  G     + +   L  G WH +  S
Sbjct: 409 PDSGDGVLLYS-YDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVS 467

Query: 460 AKWSHMNVVVDDDTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRL 516
               +  + VD    V+ +       I      + GG             L  F G ++ 
Sbjct: 468 RTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQK 527

Query: 517 ITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGT 576
           I + D+ +    V+           ++       C+ + C HGG C    + + CDC   
Sbjct: 528 IILNDRTIH---VKHDFTSG-----VNVENAAHPCVRAPCAHGGSCRPRKEGYDCDC-PL 578

Query: 577 GYTGETCHSSLYE 589
           G+ G  C  ++ E
Sbjct: 579 GFEGLHCQKAIIE 591



 Score = 37.4 bits (85), Expect = 0.093
 Identities = 80/383 (20%), Positives = 135/383 (35%), Gaps = 63/383 (16%)

Query: 189 QSALLYTLDKKPLKPIRDV----ISLKFKAMQSNGILLHR-EGQHGNHITLELIKGKLVF 243
           +S   Y     PL+P   +      + F+    +G+LL+  +    + +++ L  G + F
Sbjct: 380 ESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEF 439

Query: 244 FLN--SGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTH-HFQAKGD 300
             +  SG   L S      LTLG+      WH + +          VDK       A+G 
Sbjct: 440 RFDCGSGTGVLRSEDP---LTLGN------WHELRVSRTAKNGILQVDKQKIVEGMAEGG 490

Query: 301 SSNLDLNFEISFGGI--LSPGRSRAFTRKSFHGCLENLYYN------------GVDVTEL 346
            + +  N +I  GG+      +  +   K F G ++ +  N            GV+V   
Sbjct: 491 FTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA 550

Query: 347 AKKHKPQILMMGNV------SFSCPQP-------------QTVPVTFLSSRSYLALPGNS 387
           A          G         + C  P             + + +     RSYL      
Sbjct: 551 AHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPD 610

Query: 388 GEDKVS-----VTFQFRTWNRAGHLLF---GELQRGSGSFVLFLKDGKLKLSLFQAGQSP 439
              +VS     V  +F+T  + G LL+     ++  S    L L+DG L  S +  G   
Sbjct: 611 ILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFS-YNLGSGV 669

Query: 440 RNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDD---DTAVQPLVAVLIDSGDTYYFGGCLG 496
            ++      NDG+WH V          + VDD    T   P +   ++     Y GG   
Sbjct: 670 ASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKE 729

Query: 497 NSSGSGCKSPLGGFQGCLRLITI 519
            +  +  +  + G  GC+   T+
Sbjct: 730 IALHTN-RQYMRGLVGCISHFTL 751



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 30/166 (18%)

Query: 852 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG----- 906
           F F+ G G   +   S T      WH V   R+     LQ++         P  G     
Sbjct: 215 FRFNCGTGVAIIV--SETKIKLGGWHTVMLYRDGLNGLLQLNN------GTPVTGQSQGQ 266

Query: 907 HVRLQLNSQLFIGGTATR---------QRGFLGCIRSLQLNGVALDLEE----RATVTPG 953
           + ++   + L++GG  +           RGF GC++SL +NG  +D+      +A     
Sbjct: 267 YSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGAD 326

Query: 954 VEPGCAGHCSTYGHLCRNGGRCRE-KRRGVTCDCAFSAYDGPFCSN 998
           V    +G C      C +GG C   K     C C    + G  C +
Sbjct: 327 VGECSSGICDEAS--CIHGGTCTAIKADSYICLCPL-GFKGRHCED 369


>gi|33469929 EGF-like, fibronectin type III and laminin G domains
            isoform 1 [Homo sapiens]
          Length = 1009

 Score = 78.6 bits (192), Expect = 4e-14
 Identities = 100/384 (26%), Positives = 154/384 (40%), Gaps = 50/384 (13%)

Query: 803  YLHFPAFHGELTADVCFFFKTTVSSGVFMENL--GITDFIRIELRAPTEVTFSFDVGNGP 860
            YL F  F  E+T      F+     GV + +   G  DF+ I L A   V F FD G+G 
Sbjct: 631  YLSFMEF--EIT------FRPDSGDGVLLYSYDTGSKDFLSINL-AGGHVEFRFDCGSGT 681

Query: 861  CEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG-HVRLQLNSQLFIG 919
                ++S  P     WH +R  R  K   LQVD+  QK+    A+G   +++ N+ +FIG
Sbjct: 682  G--VLRSEDPLTLGNWHELRVSRTAKNGILQVDK--QKIVEGMAEGGFTQIKCNTDIFIG 737

Query: 920  GTATRQ---------RGFLGCIRSLQLNGVALDLEERATVTPGVEPGCAGHCSTYGHLCR 970
            G              + F G I+ + LN   + ++     T GV    A H       C 
Sbjct: 738  GVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKH--DFTSGVNVENAAHPCVRAP-CA 794

Query: 971  NGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEHYTLSENSSSLVSS 1030
            +GG CR ++ G  CDC    ++G  C   I         +       Y   +N   L   
Sbjct: 795  HGGSCRPRKEGYDCDCPL-GFEGLHCQKAI----IEAIEIPQFIGRSYLTYDNPDIL--- 846

Query: 1031 LYRDVTLTREMITLSFRTTRSPSLLLYVSSF----YEEYLSVILANNGSLQIRYKLDRHQ 1086
              + V+ +R  + + F+TT    LLL+          +++S+ L  +G+L   Y L    
Sbjct: 847  --KRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGL-RDGALVFSYNLGSGV 903

Query: 1087 NPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQ-SAKKQVILSSGTEFNAVKSLILGK 1145
                    F    DG+ H+VK  R+     + V+   A+         + N   +L +G 
Sbjct: 904  ASIMVNGSFN---DGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGG 960

Query: 1146 VLEAAGADPDTRRAATSGFTGCLS 1169
            + E A     T R    G  GC+S
Sbjct: 961  MKEIA---LHTNRQYMRGLVGCIS 981



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 95/433 (21%), Positives = 157/433 (36%), Gaps = 69/433 (15%)

Query: 208 ISLKFKAMQSNGILLH-REGQHG--NHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLG 264
           I+L+F+A   +G+LL+  E +HG  + ++L +I+  L F  N G   +   ++   + LG
Sbjct: 411 ITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTG-VAIIVSETKIKLG 469

Query: 265 SLLDDQHWHSVLIELLDTQVNFTVDKHTHHF-QAKGDSSNLDLNFEISFGGILSP-GRSR 322
                  WH+V++          ++  T    Q++G  S +     +  GG  S     R
Sbjct: 470 G------WHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVR 523

Query: 323 AF-TRKSFHGCLENLYYNG----------------VDVTELAKK--------HKPQILMM 357
           A  T + F GC+++L  NG                 DV E +          H      +
Sbjct: 524 ATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAI 583

Query: 358 GNVSFSCPQPQ-------------TVPVTFLSSRSYLALPGNSGEDKVSVTFQ-----FR 399
              S+ C  P              T+P    S RSY A P    E +  ++F      FR
Sbjct: 584 KADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPL-EPQHYLSFMEFEITFR 642

Query: 400 TWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFS 459
             +  G LL+     GS  F+     G      F  G     + +   L  G WH +  S
Sbjct: 643 PDSGDGVLLYS-YDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVS 701

Query: 460 AKWSHMNVVVDDDTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRL 516
               +  + VD    V+ +       I      + GG             L  F G ++ 
Sbjct: 702 RTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQK 761

Query: 517 ITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCLGT 576
           I + D+ +    V+           ++       C+ + C HGG C    + + CDC   
Sbjct: 762 IILNDRTIH---VKHDFTSG-----VNVENAAHPCVRAPCAHGGSCRPRKEGYDCDC-PL 812

Query: 577 GYTGETCHSSLYE 589
           G+ G  C  ++ E
Sbjct: 813 GFEGLHCQKAIIE 825



 Score = 37.4 bits (85), Expect = 0.093
 Identities = 80/383 (20%), Positives = 135/383 (35%), Gaps = 63/383 (16%)

Query: 189 QSALLYTLDKKPLKPIRDV----ISLKFKAMQSNGILLHR-EGQHGNHITLELIKGKLVF 243
           +S   Y     PL+P   +      + F+    +G+LL+  +    + +++ L  G + F
Sbjct: 614 ESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEF 673

Query: 244 FLN--SGNAKLPSTIAPVTLTLGSLLDDQHWHSVLIELLDTQVNFTVDKHTH-HFQAKGD 300
             +  SG   L S      LTLG+      WH + +          VDK       A+G 
Sbjct: 674 RFDCGSGTGVLRSEDP---LTLGN------WHELRVSRTAKNGILQVDKQKIVEGMAEGG 724

Query: 301 SSNLDLNFEISFGGI--LSPGRSRAFTRKSFHGCLENLYYN------------GVDVTEL 346
            + +  N +I  GG+      +  +   K F G ++ +  N            GV+V   
Sbjct: 725 FTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENA 784

Query: 347 AKKHKPQILMMGNV------SFSCPQP-------------QTVPVTFLSSRSYLALPGNS 387
           A          G         + C  P             + + +     RSYL      
Sbjct: 785 AHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPD 844

Query: 388 GEDKVS-----VTFQFRTWNRAGHLLF---GELQRGSGSFVLFLKDGKLKLSLFQAGQSP 439
              +VS     V  +F+T  + G LL+     ++  S    L L+DG L  S +  G   
Sbjct: 845 ILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFS-YNLGSGV 903

Query: 440 RNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDD---DTAVQPLVAVLIDSGDTYYFGGCLG 496
            ++      NDG+WH V          + VDD    T   P +   ++     Y GG   
Sbjct: 904 ASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKE 963

Query: 497 NSSGSGCKSPLGGFQGCLRLITI 519
            +  +  +  + G  GC+   T+
Sbjct: 964 IALHTN-RQYMRGLVGCISHFTL 985



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 40/166 (24%), Positives = 62/166 (37%), Gaps = 30/166 (18%)

Query: 852 FSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADG----- 906
           F F+ G G   +   S T      WH V   R+     LQ++         P  G     
Sbjct: 449 FRFNCGTGVAIIV--SETKIKLGGWHTVMLYRDGLNGLLQLNN------GTPVTGQSQGQ 500

Query: 907 HVRLQLNSQLFIGGTATR---------QRGFLGCIRSLQLNGVALDLEE----RATVTPG 953
           + ++   + L++GG  +           RGF GC++SL +NG  +D+      +A     
Sbjct: 501 YSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGAD 560

Query: 954 VEPGCAGHCSTYGHLCRNGGRCRE-KRRGVTCDCAFSAYDGPFCSN 998
           V    +G C      C +GG C   K     C C    + G  C +
Sbjct: 561 VGECSSGICDEAS--CIHGGTCTAIKADSYICLCPL-GFKGRHCED 603


>gi|33469935 EGF-like, fibronectin type III and laminin G domains
            isoform 3 [Homo sapiens]
          Length = 375

 Score = 78.2 bits (191), Expect = 5e-14
 Identities = 91/356 (25%), Positives = 144/356 (40%), Gaps = 40/356 (11%)

Query: 829  VFMENLGITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGA 888
            ++  + G  DF+ I L A   V F FD G+G     ++S  P     WH +R  R  K  
Sbjct: 17   LYSYDTGSKDFLSINL-AGGHVEFRFDCGSGTG--VLRSEDPLTLGNWHELRVSRTAKNG 73

Query: 889  SLQVDQLPQKMQPAPADG-HVRLQLNSQLFIGGTATRQ---------RGFLGCIRSLQLN 938
             LQVD+  QK+    A+G   +++ N+ +FIGG              + F G I+ + LN
Sbjct: 74   ILQVDK--QKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILN 131

Query: 939  GVALDLEERATVTPGVEPGCAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSN 998
               + ++     T GV    A H       C +GG CR ++ G  CDC    ++G  C  
Sbjct: 132  DRTIHVKH--DFTSGVNVENAAHPCVRAP-CAHGGSCRPRKEGYDCDCPL-GFEGLHCQK 187

Query: 999  EISAYFATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYV 1058
             I         +       Y   +N   L     + V+ +R  + + F+TT    LLL+ 
Sbjct: 188  AI----IEAIEIPQFIGRSYLTYDNPDIL-----KRVSGSRSNVFMRFKTTAKDGLLLWR 238

Query: 1059 SSF----YEEYLSVILANNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAV 1114
                     +++S+ L  +G+L   Y L            F    DG+ H+VK  R+   
Sbjct: 239  GDSPMRPNSDFISLGL-RDGALVFSYNLGSGVASIMVNGSFN---DGRWHRVKAVRDGQS 294

Query: 1115 VMVEVNQ-SAKKQVILSSGTEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLS 1169
              + V+   A+         + N   +L +G + E A     T R    G  GC+S
Sbjct: 295  GKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIA---LHTNRQYMRGLVGCIS 347



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 75/358 (20%), Positives = 127/358 (35%), Gaps = 59/358 (16%)

Query: 210 LKFKAMQSNGILLHR-EGQHGNHITLELIKGKLVFFLN--SGNAKLPSTIAPVTLTLGSL 266
           + F+    +G+LL+  +    + +++ L  G + F  +  SG   L S      LTLG+ 
Sbjct: 5   ITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDP---LTLGN- 60

Query: 267 LDDQHWHSVLIELLDTQVNFTVDKHTH-HFQAKGDSSNLDLNFEISFGGI--LSPGRSRA 323
                WH + +          VDK       A+G  + +  N +I  GG+      +  +
Sbjct: 61  -----WHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNS 115

Query: 324 FTRKSFHGCLENLYYN------------GVDVTELAKKHKPQILMMGNV------SFSCP 365
              K F G ++ +  N            GV+V   A          G         + C 
Sbjct: 116 GVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCD 175

Query: 366 QP-------------QTVPVTFLSSRSYLALPGNSGEDKVS-----VTFQFRTWNRAGHL 407
            P             + + +     RSYL         +VS     V  +F+T  + G L
Sbjct: 176 CPLGFEGLHCQKAIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLL 235

Query: 408 LF---GELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSH 464
           L+     ++  S    L L+DG L  S +  G    ++      NDG+WH V        
Sbjct: 236 LWRGDSPMRPNSDFISLGLRDGALVFS-YNLGSGVASIMVNGSFNDGRWHRVKAVRDGQS 294

Query: 465 MNVVVDD---DTAVQPLVAVLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCLRLITI 519
             + VDD    T   P +   ++     Y GG    +  +  +  + G  GC+   T+
Sbjct: 295 GKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTN-RQYMRGLVGCISHFTL 351



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 41/195 (21%), Positives = 67/195 (34%), Gaps = 13/195 (6%)

Query: 398 FRTWNRAGHLLFGELQRGSGSFVLFLKDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVS 457
           FR  +  G LL+     GS  F+     G      F  G     + +   L  G WH + 
Sbjct: 7   FRPDSGDGVLLYS-YDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELR 65

Query: 458 FSAKWSHMNVVVDDDTAVQPLVA---VLIDSGDTYYFGGCLGNSSGSGCKSPLGGFQGCL 514
            S    +  + VD    V+ +       I      + GG             L  F G +
Sbjct: 66  VSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSI 125

Query: 515 RLITIGDKAVDPILVQQGALGSFRDLQIDSCGITDRCLPSYCEHGGECSQSWDTFSCDCL 574
           + I + D+ +    V+           ++       C+ + C HGG C    + + CDC 
Sbjct: 126 QKIILNDRTIH---VKHDFTSG-----VNVENAAHPCVRAPCAHGGSCRPRKEGYDCDC- 176

Query: 575 GTGYTGETCHSSLYE 589
             G+ G  C  ++ E
Sbjct: 177 PLGFEGLHCQKAIIE 191


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 61/227 (26%), Positives = 96/227 (42%), Gaps = 14/227 (6%)

Query: 364  CPQPQTVPVTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELQRGSGSFVLFL 423
            C +    PV     RS+LA P       + +  +FR     G LL+    RG     L L
Sbjct: 1366 CEKVLGAPVPAFEGRSFLAFPTLRAYHTLRLALEFRALEPQGLLLYNGNARGKDFLALAL 1425

Query: 424  KDGKLKLSLFQAGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVA 480
             DG+++L  F  G  P  +T+   +  GQWH +  S  W    + VD +T V    P   
Sbjct: 1426 LDGRVQLR-FDTGSGPAVLTSAVPVEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGT 1484

Query: 481  VLIDSGDTYYFGGCLGNSSGSGCKSPL--GGFQGCLRLITIGDKAVDPILVQQGALGSFR 538
              ++     + GG   + +    +      G +GC+RL+ + ++ ++   +  G   + R
Sbjct: 1485 DGLNLDTDLFVGGVPEDQAAVALERTFVGAGLRGCIRLLDVNNQRLE---LGIGPGAATR 1541

Query: 539  DLQIDSCGITDRCLPSYCEHGGECSQSWDT--FSCDCLGTGYTGETC 583
               +  CG    CLP+ C HGG   Q+ +   F C C   G  G TC
Sbjct: 1542 GSGVGECG-DHPCLPNPC-HGGAPCQNLEAGRFHCQC-PPGRVGPTC 1585



 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 96/354 (27%), Positives = 138/354 (38%), Gaps = 28/354 (7%)

Query: 835  GITDFIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ 894
            G  DF+ + LR    + F +D+G G     ++S  P     W  V  ERN +  +L+V  
Sbjct: 1686 GKGDFVSLALR-DRRLEFRYDLGKGAA--VIRSREPVTLGAWTRVSLERNGRKGALRVGD 1742

Query: 895  LPQKMQPAPADGHVRLQLNSQLFIGGT---------ATRQRGFLGCIRSLQLNGVALDLE 945
             P+ +  +P   H  L L   L++GG          A    GF G I+ + L G  L   
Sbjct: 1743 GPRVLGESPVP-HTVLNLKEPLYVGGAPDFSKLARAAAVSSGFDGAIQLVSLGGRQLLTP 1801

Query: 946  ERATVTPGVEPGCAGHCSTY--GHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAY 1003
            E       V    AGH  T   GH C NG  C  +     C C    + GP C   +   
Sbjct: 1802 EHVLRQVDVT-SFAGHPCTRASGHPCLNGASCVPREAAYVCLCP-GGFSGPHCEKGLVEK 1859

Query: 1004 FATGSSMTYHFQEHYTLSENSSSLVSSLYRDVTLTREMITLSFRTTRSPSLLLYVSSFYE 1063
             A G   T  F +  T  E  +++  S   +  L      LS RT  +  L+L+     E
Sbjct: 1860 SA-GDVDTLAF-DGRTFVEYLNAVTES---EKALQSNHFELSLRTEATQGLVLWSGKATE 1914

Query: 1064 EYLSVILA-NNGSLQIRYKLDRHQNPDAFTFDFKNMADGQLHQVKINREEAVVMVEVNQS 1122
                V LA  +G LQ+ Y L         T         +  +V  +RE+    ++V   
Sbjct: 1915 RADYVALAIVDGHLQLSYNLGSQPVVLRSTVPVNT---NRWLRVVAHREQREGSLQVGNE 1971

Query: 1123 AKKQVILSSG-TEFNAVKSLILGKVLEAAGADPDTRRAATSGFTGCLSAVRFGR 1175
            A        G T+ +   +L LG + E     P   +A  +GF GCL  V  GR
Sbjct: 1972 APVTGSSPLGATQLDTDGALWLGGLPELP-VGPALPKAYGTGFVGCLRDVVVGR 2024



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 49/209 (23%), Positives = 87/209 (41%), Gaps = 15/209 (7%)

Query: 390  DKVSVTFQFRTWNRAGHLLF-GELQRGSGSFV-LFLKDGKLKLSLFQAGQSPRNVTAGAG 447
            +K+++   F     +G LL+ G+   G G FV L L+D +L+   +  G+    + +   
Sbjct: 1660 EKMALEVVFLARGPSGLLLYNGQKTDGKGDFVSLALRDRRLEFR-YDLGKGAAVIRSREP 1718

Query: 448  LNDGQWHSVSFSAKWSHMNVVVDDDTAV---QPLVAVLIDSGDTYYFGGCLGNSSGSGCK 504
            +  G W  VS         + V D   V    P+   +++  +  Y GG    S  +   
Sbjct: 1719 VTLGAWTRVSLERNGRKGALRVGDGPRVLGESPVPHTVLNLKEPLYVGGAPDFSKLARAA 1778

Query: 505  SPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQIDSCG--ITDRCLPSYCEHGGEC 562
            +   GF G ++L+++G +    +L  +  L   R + + S       R     C +G  C
Sbjct: 1779 AVSSGFDGAIQLVSLGGR---QLLTPEHVL---RQVDVTSFAGHPCTRASGHPCLNGASC 1832

Query: 563  SQSWDTFSCDCLGTGYTGETCHSSLYEQS 591
                  + C C G G++G  C   L E+S
Sbjct: 1833 VPREAAYVCLCPG-GFSGPHCEKGLVEKS 1860



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 33/114 (28%), Positives = 51/114 (44%), Gaps = 13/114 (11%)

Query: 853  SFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQLPQKMQPAPADGHVRLQL 912
            S+++G+ P  V ++S  P N N+W  V A R  +  SLQV         +P  G  +L  
Sbjct: 1931 SYNLGSQP--VVLRSTVPVNTNRWLRVVAHREQREGSLQVGNEAPVTGSSPL-GATQLDT 1987

Query: 913  NSQLFIGG----------TATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEP 956
            +  L++GG                GF+GC+R + +    L L E A   P + P
Sbjct: 1988 DGALWLGGLPELPVGPALPKAYGTGFVGCLRDVVVGRHPLHLLEDAVTKPELRP 2041



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 29/138 (21%), Positives = 61/138 (44%), Gaps = 13/138 (9%)

Query: 208  ISLKFKAMQSNGILLHREGQHG-NHITLELIKGKLVFFLNSGNAKLPSTIAPVTLTLGSL 266
            ++L+F+A++  G+LL+     G + + L L+ G++    ++G+        P  LT    
Sbjct: 1396 LALEFRALEPQGLLLYNGNARGKDFLALALLDGRVQLRFDTGS-------GPAVLTSAVP 1448

Query: 267  LDDQHWHSVLIELLDTQVNFTVDKHTHHF-QAKGDSSNLDLNFEISFGGI----LSPGRS 321
            ++   WH + +     +   +VD  T    ++   +  L+L+ ++  GG+     +    
Sbjct: 1449 VEPGQWHRLELSRHWRRGTLSVDGETPVLGESPSGTDGLNLDTDLFVGGVPEDQAAVALE 1508

Query: 322  RAFTRKSFHGCLENLYYN 339
            R F      GC+  L  N
Sbjct: 1509 RTFVGAGLRGCIRLLDVN 1526


>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
           sapiens]
          Length = 1158

 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 50/150 (33%), Positives = 69/150 (46%), Gaps = 11/150 (7%)

Query: 46  SSSELSSSHGPGFSRLNRRDGA-------GGWTPLVSNKYQWLQIDLGERMEVTAVATQG 98
           +SS L    G    RLN + GA       G W      + QW+++D       T V TQG
Sbjct: 402 ASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQG 461

Query: 99  GYGS--SDWVTSYLLMFSDGGRNWKQYRREESIWGFPGNTNADSVVHYRLQPPFEARFLR 156
              S   D+VT++ + FS+  + W  Y        F GN + D+ V   L  P  ARF+R
Sbjct: 462 RDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIR 521

Query: 157 FLPLAWNPRGRIGMRIEVYGCAYKSEVVYF 186
             PL WN  G + MR+EV GC+      Y+
Sbjct: 522 IYPLTWN--GSLCMRLEVLGCSVAPVYSYY 549


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,627,257
Number of Sequences: 37866
Number of extensions: 2580188
Number of successful extensions: 8666
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 7362
Number of HSP's gapped (non-prelim): 1015
length of query: 1288
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1174
effective length of database: 13,930,794
effective search space: 16354752156
effective search space used: 16354752156
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press