Guide to the Human Genome
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Search of human proteins with 239743600

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo
sapiens]
         (675 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743602 PREDICTED: hypothetical protein XP_002342903 [Homo ...  1373   0.0  
gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo ...  1373   0.0  
gi|239743598 PREDICTED: hypothetical protein XP_002342901 [Homo ...  1373   0.0  
gi|239743596 PREDICTED: hypothetical protein XP_002342900 [Homo ...  1373   0.0  
gi|126273519 exonuclease GOR [Homo sapiens]                          1371   0.0  
gi|239743594 PREDICTED: hypothetical protein XP_002342913, parti...  1118   0.0  
gi|145199237 transcription elongation factor B polypeptide 3 bin...   691   0.0  
gi|222136615 exonuclease NEF-sp isoform 2 [Homo sapiens]              108   1e-23
gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens]              108   1e-23
gi|194239666 interferon stimulated exonuclease gene 20kDa-like 1...    81   4e-15
gi|6857800 interferon stimulated exonuclease [Homo sapiens]            74   4e-13
gi|13569960 interferon stimulated exonuclease gene 20kDa-like 2 ...    67   7e-11
gi|76781492 XPMC2 prevents mitotic catastrophe 2 homolog [Homo s...    56   9e-08
gi|188536114 PAN2 polyA specific ribonuclease subunit homolog is...    48   3e-05
gi|188536112 PAN2 polyA specific ribonuclease subunit homolog is...    48   3e-05
gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]              44   6e-04
gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ...    40   0.005
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ...    40   0.005
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        40   0.005
gi|163965366 nascent polypeptide-associated complex alpha subuni...    40   0.009
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    37   0.060
gi|122937321 UNC homeobox [Homo sapiens]                               37   0.078
gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isof...    36   0.10 
gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isofo...    36   0.10 
gi|37693995 Kruppel-like factor 13 [Homo sapiens]                      35   0.17 
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    35   0.23 
gi|14602439 Williams Beuren syndrome chromosome region 14 isofor...    35   0.30 
gi|14602437 Williams Beuren syndrome chromosome region 14 isofor...    35   0.30 
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    35   0.30 
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    35   0.30 

>gi|239743602 PREDICTED: hypothetical protein XP_002342903 [Homo
           sapiens]
          Length = 675

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 675/675 (100%), Positives = 675/675 (100%)

Query: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60
           MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY
Sbjct: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60

Query: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
           PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA
Sbjct: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120

Query: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180
           PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR
Sbjct: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180

Query: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240
           GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS
Sbjct: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240

Query: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300
           KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY
Sbjct: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300

Query: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360
           LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG
Sbjct: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360

Query: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420
           LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE
Sbjct: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420

Query: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480
           YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE
Sbjct: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480

Query: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540
           SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE
Sbjct: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540

Query: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600
           IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV
Sbjct: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600

Query: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660
           DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI
Sbjct: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660

Query: 661 QPRHRSASPAALACP 675
           QPRHRSASPAALACP
Sbjct: 661 QPRHRSASPAALACP 675


>gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo
           sapiens]
          Length = 675

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 675/675 (100%), Positives = 675/675 (100%)

Query: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60
           MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY
Sbjct: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60

Query: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
           PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA
Sbjct: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120

Query: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180
           PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR
Sbjct: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180

Query: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240
           GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS
Sbjct: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240

Query: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300
           KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY
Sbjct: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300

Query: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360
           LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG
Sbjct: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360

Query: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420
           LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE
Sbjct: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420

Query: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480
           YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE
Sbjct: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480

Query: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540
           SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE
Sbjct: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540

Query: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600
           IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV
Sbjct: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600

Query: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660
           DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI
Sbjct: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660

Query: 661 QPRHRSASPAALACP 675
           QPRHRSASPAALACP
Sbjct: 661 QPRHRSASPAALACP 675


>gi|239743598 PREDICTED: hypothetical protein XP_002342901 [Homo
           sapiens]
          Length = 675

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 675/675 (100%), Positives = 675/675 (100%)

Query: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60
           MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY
Sbjct: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60

Query: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
           PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA
Sbjct: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120

Query: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180
           PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR
Sbjct: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180

Query: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240
           GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS
Sbjct: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240

Query: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300
           KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY
Sbjct: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300

Query: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360
           LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG
Sbjct: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360

Query: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420
           LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE
Sbjct: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420

Query: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480
           YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE
Sbjct: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480

Query: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540
           SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE
Sbjct: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540

Query: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600
           IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV
Sbjct: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600

Query: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660
           DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI
Sbjct: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660

Query: 661 QPRHRSASPAALACP 675
           QPRHRSASPAALACP
Sbjct: 661 QPRHRSASPAALACP 675


>gi|239743596 PREDICTED: hypothetical protein XP_002342900 [Homo
           sapiens]
          Length = 675

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 675/675 (100%), Positives = 675/675 (100%)

Query: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60
           MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY
Sbjct: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60

Query: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
           PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA
Sbjct: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120

Query: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180
           PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR
Sbjct: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180

Query: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240
           GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS
Sbjct: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240

Query: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300
           KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY
Sbjct: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300

Query: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360
           LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG
Sbjct: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360

Query: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420
           LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE
Sbjct: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420

Query: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480
           YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE
Sbjct: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480

Query: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540
           SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE
Sbjct: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540

Query: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600
           IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV
Sbjct: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600

Query: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660
           DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI
Sbjct: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660

Query: 661 QPRHRSASPAALACP 675
           QPRHRSASPAALACP
Sbjct: 661 QPRHRSASPAALACP 675


>gi|126273519 exonuclease GOR [Homo sapiens]
          Length = 675

 Score = 1371 bits (3549), Expect = 0.0
 Identities = 674/675 (99%), Positives = 675/675 (100%)

Query: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60
           MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY
Sbjct: 1   MLRATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGY 60

Query: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
           PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA
Sbjct: 61  PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120

Query: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180
           PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR
Sbjct: 121 PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180

Query: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240
           GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS
Sbjct: 181 GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240

Query: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300
           KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY
Sbjct: 241 KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGY 300

Query: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360
           LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG
Sbjct: 301 LQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPG 360

Query: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420
           LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE
Sbjct: 361 LSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTE 420

Query: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480
           YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE
Sbjct: 421 YLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKE 480

Query: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540
           SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE
Sbjct: 481 SLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNE 540

Query: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600
           IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV
Sbjct: 541 IVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVV 600

Query: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQI 660
           DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDA+ACLQLVMWKVRQRAQI
Sbjct: 601 DTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDASACLQLVMWKVRQRAQI 660

Query: 661 QPRHRSASPAALACP 675
           QPRHRSASPAALACP
Sbjct: 661 QPRHRSASPAALACP 675


>gi|239743594 PREDICTED: hypothetical protein XP_002342913, partial
           [Homo sapiens]
          Length = 552

 Score = 1118 bits (2893), Expect = 0.0
 Identities = 552/552 (100%), Positives = 552/552 (100%)

Query: 124 PLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSA 183
           PLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSA
Sbjct: 1   PLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSA 60

Query: 184 CRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKVG 243
           CRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKVG
Sbjct: 61  CRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKVG 120

Query: 244 RQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGYLQL 303
           RQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGYLQL
Sbjct: 121 RQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRRGYLQL 180

Query: 304 FTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPGLSR 363
           FTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPGLSR
Sbjct: 181 FTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPGLSR 240

Query: 364 AALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTEYLV 423
           AALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTEYLV
Sbjct: 241 AALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSSCRVCCRCGTEYLV 300

Query: 424 SSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKESLD 483
           SSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKESLD
Sbjct: 301 SSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVAKQHVRDGRKESLD 360

Query: 484 GFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVD 543
           GFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVD
Sbjct: 361 GFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVD 420

Query: 544 YNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTA 603
           YNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTA
Sbjct: 421 YNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTA 480

Query: 604 VLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQIQPR 663
           VLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQIQPR
Sbjct: 481 VLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQIQPR 540

Query: 664 HRSASPAALACP 675
           HRSASPAALACP
Sbjct: 541 HRSASPAALACP 552


>gi|145199237 transcription elongation factor B polypeptide 3 binding
            protein 1 [Homo sapiens]
          Length = 1221

 Score =  691 bits (1784), Expect = 0.0
 Identities = 360/549 (65%), Positives = 408/549 (74%), Gaps = 43/549 (7%)

Query: 152  QAEPQNRGPAVPPAWPKMVTESCYF---PAQRGSACRLPAAPRLTERPSGVRISAPRKRK 208
            + EP  RGPAVPPA P    E CY     AQR SA  L A  RL E+   V ISAP +++
Sbjct: 672  EVEPPRRGPAVPPARPPTAQEVCYLRAQQAQRASASLLQAPARLAEKSPSVHISAPGEKR 731

Query: 209  TIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTATTSSKRI 268
             IAH  +P L    T AKRT  AS SQ S G + G Q  KTR  SGMA KTT T   KRI
Sbjct: 732  RIAHIPNPRLAAAPTGAKRTLAASGSQSSNGPEPGGQQLKTRTLSGMASKTTTTIIPKRI 791

Query: 269  VRRASLPSLSLKKPIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKV 328
                SL SL  KKPII +  G +VPTV+R+ YL LF EECLKFC S QEA EKALNEEKV
Sbjct: 792  AHSPSLQSL--KKPIIPKEFGGKVPTVIRQRYLNLFIEECLKFCTSNQEAIEKALNEEKV 849

Query: 329  AYDCSPNKNRYLNVVLNTLKRLKGLTPSSMPGLSR------------------------- 363
            AYD SP+KN YLNV +NTLK+L+GL PS++PGLS+                         
Sbjct: 850  AYDRSPSKNIYLNVAVNTLKKLRGLAPSAVPGLSKTSGRRVVSHEVVLGGRLAAKTSFSL 909

Query: 364  -------------AALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTGQGKGPGDSS 410
                         AALYSRL+E+LLTQDQLKENGYPFPHPERPGGA++FT + K P DSS
Sbjct: 910  SRPSSPRVEDLKGAALYSRLREYLLTQDQLKENGYPFPHPERPGGAIIFTAEEKRPKDSS 969

Query: 411  CRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGGRVSQYTCCAAAPGSVGCQVA 470
            CR CCRCGTEYLVSSSGRC+RD+ CYYHWGR+R ++VAGG  +QY CC+AA GSVGCQVA
Sbjct: 970  CRTCCRCGTEYLVSSSGRCIRDEECYYHWGRLRRNRVAGGWETQYMCCSAAAGSVGCQVA 1029

Query: 471  KQHVRDGRKESLDGFVETFKKELSRDAYPGIYALDCEMCYTTHGLELTRVTVVDADMRVV 530
            KQHV+DGRKE L+GFV+TF+KELS D +PGIYALDCEM YTT+GLELTRVTVVD D+ VV
Sbjct: 1030 KQHVQDGRKERLEGFVKTFEKELSGDTHPGIYALDCEMSYTTYGLELTRVTVVDTDVHVV 1089

Query: 531  YDTFVKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFSAQTILIGHSLESDLL 590
            YDTFVKPDNEIVDYNTRFSGVTEAD+A TS+TL  VQA+LLS FSA TILIGHSLESDLL
Sbjct: 1090 YDTFVKPDNEIVDYNTRFSGVTEADLADTSVTLRDVQAVLLSMFSADTILIGHSLESDLL 1149

Query: 591  ALKLIHSTVVDTAVLFPHYLGFPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLV 650
            ALK+IHSTVVDT+VLFPH LG PYKRSLRNL ADYL QIIQD+ DGH+SSEDA AC+ LV
Sbjct: 1150 ALKVIHSTVVDTSVLFPHRLGLPYKRSLRNLMADYLRQIIQDNVDGHSSSEDAGACMHLV 1209

Query: 651  MWKVRQRAQ 659
            +WKVR+ A+
Sbjct: 1210 IWKVREDAK 1218



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 54/253 (21%), Positives = 88/253 (34%), Gaps = 44/253 (17%)

Query: 64  KKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEF 123
           KK    A P A+   G    PA  P  +      A      G P   ++ +  + +AP  
Sbjct: 434 KKKPSSATPVATSGKGRPDRPARRPSPTSGDSRPAA---GRGPPRPLQLPDRKSTKAPSG 490

Query: 124 PLPSHQPA---QSFGLWVPQMHKQASAFVDI---QAEPQNRGPAVPPAWPKMV------- 170
            L   +     +      P++ K+A +  D+   ++E +  GP VP  WP  +       
Sbjct: 491 KLVERKARSLDEGASQDAPKLKKRALSHADLFGDESEDEAAGPGVPSVWPSALPSLSSDS 550

Query: 171 ----TESCYFPAQRGSACRLPAAPRLTERPS------------GVRISAPRKRKTIAHSS 214
                 S  FP  +G   RL A+P  +  PS            G  +      K +   S
Sbjct: 551 DSDSDSSLGFPEAQGPPKRLKASPPPSPAPSSSSSSSSSTSSAGADVDYSALEKEVDFDS 610

Query: 215 SP---CLVTGYTDAKRTRVASSSQRSRGSKVGRQPGKTR--NRSGMACKTTATTSSKRIV 269
            P   CL       +    ++S +     ++ RQP K       G++  TT     KR +
Sbjct: 611 DPMEECL-------RIFNESTSVKTEDRGRLARQPPKEEKSEEKGLSGLTTLFPGQKRRI 663

Query: 270 RRASLPSLSLKKP 282
              S     ++ P
Sbjct: 664 SHLSKQGQEVEPP 676


>gi|222136615 exonuclease NEF-sp isoform 2 [Homo sapiens]
          Length = 743

 Score =  108 bits (271), Expect = 1e-23
 Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)

Query: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
           ++ LDCEMC T+ G ELTR+++V      V D  VKP+N+I+DY T FSG+T+  +   +
Sbjct: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287

Query: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
             L  VQ  L +      +L+GHSL+ DL ALK+IH  V+DT++L+    G  +K  L+ 
Sbjct: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345

Query: 621 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 652
           LA   L + IQ   + GH+++EDA   L+L  +
Sbjct: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378


>gi|222136613 exonuclease NEF-sp isoform 1 [Homo sapiens]
          Length = 774

 Score =  108 bits (271), Expect = 1e-23
 Identities = 62/153 (40%), Positives = 93/153 (60%), Gaps = 3/153 (1%)

Query: 501 IYALDCEMCYTTHGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTS 560
           ++ LDCEMC T+ G ELTR+++V      V D  VKP+N+I+DY T FSG+T+  +   +
Sbjct: 228 LFGLDCEMCLTSKGRELTRISLVAEGGCCVMDELVKPENKILDYLTSFSGITKKILNPVT 287

Query: 561 ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIHSTVVDTAVLFPHYLGFPYKRSLRN 620
             L  VQ  L +      +L+GHSL+ DL ALK+IH  V+DT++L+    G  +K  L+ 
Sbjct: 288 TKLKDVQRQLKALLPPDAVLVGHSLDLDLRALKMIHPYVIDTSLLYVREQGRRFK--LKF 345

Query: 621 LAADYLAQIIQ-DSQDGHNSSEDANACLQLVMW 652
           LA   L + IQ   + GH+++EDA   L+L  +
Sbjct: 346 LAKVILGKDIQCPDRLGHDATEDARTILELARY 378


>gi|194239666 interferon stimulated exonuclease gene 20kDa-like 1
           [Homo sapiens]
          Length = 325

 Score = 80.9 bits (198), Expect = 4e-15
 Identities = 56/169 (33%), Positives = 90/169 (53%), Gaps = 18/169 (10%)

Query: 503 ALDCEMCYTT---HGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKT 559
           A+DCEM  T       EL R ++V     V+YD +++P+  I DY TR+SG+T   + K 
Sbjct: 112 AIDCEMVGTGPRGRVSELARCSIVSYHGNVLYDKYIRPEMPIADYRTRWSGITRQHMRK- 170

Query: 560 SITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIH--STVVDTAVLFPHYLGFP---- 613
           ++     Q  +L     + +++GH+L +D  ALK +H  S   DT  + P++L  P    
Sbjct: 171 AVPFQVAQKEILKLLKGK-VVVGHALHNDFQALKYVHPRSQTRDTTYV-PNFLSEPGLHT 228

Query: 614 -YKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQL-----VMWKVRQ 656
             + SL++LA   L + IQ  Q GH+S EDA   ++L     V W+ ++
Sbjct: 229 RARVSLKDLALQLLHKKIQVGQHGHSSVEDATTAMELYRLVEVQWEQQE 277


>gi|6857800 interferon stimulated exonuclease [Homo sapiens]
          Length = 181

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 57/168 (33%), Positives = 86/168 (51%), Gaps = 12/168 (7%)

Query: 501 IYALDCEMCYTTHGLE--LTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVT-EADVA 557
           + A+DCEM       E  L R ++V+    V+YD F++P+ EI DY TR SGVT +  V 
Sbjct: 7   VVAMDCEMVGLGPHRESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVG 66

Query: 558 KTSITLPQVQAILLSFFSAQTILIGHSLESDLLALK------LIHSTVVDTAVLFPHYLG 611
            T   + +++ + L       +++GH L+ D  ALK       I+ T  D  +     L 
Sbjct: 67  ATPFAVARLEILQL---LKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLD 123

Query: 612 FPYKRSLRNLAADYLAQIIQDSQDGHNSSEDANACLQLVMWKVRQRAQ 659
              + SLR L+   L + IQ+S  GH+S EDA A ++L     R RA+
Sbjct: 124 HCRRVSLRVLSERLLHKSIQNSLLGHSSVEDARATMELYQISQRIRAR 171


>gi|13569960 interferon stimulated exonuclease gene 20kDa-like 2
           [Homo sapiens]
          Length = 353

 Score = 66.6 bits (161), Expect = 7e-11
 Identities = 52/159 (32%), Positives = 81/159 (50%), Gaps = 17/159 (10%)

Query: 503 ALDCEMCYTT---HGLELTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKT 559
           A+DCEM  T    H   L R ++V+ +  V+YD ++ P   IVDY TR+SG+ +  +   
Sbjct: 181 AIDCEMVGTGPKGHVSSLARCSIVNYNGDVLYDEYILPPCHIVDYRTRWSGIRKQHMVNA 240

Query: 560 S---ITLPQVQAILLSFFSAQTILIGHSLESDLLALKLIH--STVVDTAVLFP--HYLGF 612
           +   I   Q+  IL        I++GH++ +D  AL+  H  S   DT+ + P       
Sbjct: 241 TPFKIARGQILKILTG-----KIVVGHAIHNDFKALQYFHPKSLTRDTSHIPPLNRKADC 295

Query: 613 PYK--RSLRNLAADYLAQIIQDSQDGHNSSEDANACLQL 649
           P     SL++L    L + IQ  + GH+S EDA A ++L
Sbjct: 296 PENATMSLKHLTKKLLNRDIQVGKSGHSSVEDAQATMEL 334


>gi|76781492 XPMC2 prevents mitotic catastrophe 2 homolog [Homo
           sapiens]
          Length = 422

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 13/197 (6%)

Query: 462 PGSVGCQVAKQHVRDGRKE--SLDGFVE-TFKKELSRDAYPGIYALDCEMCYTTHGLE-- 516
           P  +   +  +  +  RK+    +G V  +  KE +        ALDCEM       E  
Sbjct: 201 PADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRALALDCEMVGVGPKGEES 260

Query: 517 -LTRVTVVDADMRVVYDTFVKPDNEIVDYNTRFSGVTEADVAKTSITLPQVQAILLSFFS 575
              RV++V+   + VYD +VKP   + DY T  SG+   ++ K    L  VQ  +     
Sbjct: 261 MAARVSIVNQYGKCVYDKYVKPTEPVTDYRTAVSGIRPENL-KQGEELEVVQKEVAEMLK 319

Query: 576 AQTILIGHSLESDLLALKLIH--STVVDTAVLFPHYLGFPYKR-SLRNLAADYLAQIIQD 632
            + IL+GH+L +DL  L L H    + DT    P        R SLR L+   L   +Q 
Sbjct: 320 GR-ILVGHALHNDLKVLFLDHPKKKIRDTQKYKPFKSQVKSGRPSLRLLSEKILGLQVQQ 378

Query: 633 SQDGHNSSEDANACLQL 649
           ++  H S +DA A ++L
Sbjct: 379 AE--HCSIQDAQAAMRL 393


>gi|188536114 PAN2 polyA specific ribonuclease subunit homolog isoform
            2 [Homo sapiens]
          Length = 1202

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 41/127 (32%), Positives = 58/127 (45%), Gaps = 15/127 (11%)

Query: 532  DTFVKPDNEIVDYNTRFSGVTEADV-----AKTSITLPQVQAILLSFFSAQTILIGHSLE 586
            D ++    ++VDY T++SG+   D+     +K   TL      L          +GH L+
Sbjct: 1026 DDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQ 1085

Query: 587  SDLLALKLI--HSTVVDTAVLFPHYLGFPYKR--SLRNLAADYLAQIIQDSQDGHNSSED 642
             D   + L+     V+DT  LF      P KR  SLR LA  +L   IQ   + H+S ED
Sbjct: 1086 KDFRVINLMVPKDQVLDTVYLF----HMPRKRMISLRFLAWYFLDLKIQG--ETHDSIED 1139

Query: 643  ANACLQL 649
            A   LQL
Sbjct: 1140 ARTALQL 1146


>gi|188536112 PAN2 polyA specific ribonuclease subunit homolog isoform
            1 [Homo sapiens]
          Length = 1198

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 41/127 (32%), Positives = 58/127 (45%), Gaps = 15/127 (11%)

Query: 532  DTFVKPDNEIVDYNTRFSGVTEADV-----AKTSITLPQVQAILLSFFSAQTILIGHSLE 586
            D ++    ++VDY T++SG+   D+     +K   TL      L          +GH L+
Sbjct: 1022 DDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFVGHGLQ 1081

Query: 587  SDLLALKLI--HSTVVDTAVLFPHYLGFPYKR--SLRNLAADYLAQIIQDSQDGHNSSED 642
             D   + L+     V+DT  LF      P KR  SLR LA  +L   IQ   + H+S ED
Sbjct: 1082 KDFRVINLMVPKDQVLDTVYLF----HMPRKRMISLRFLAWYFLDLKIQG--ETHDSIED 1135

Query: 643  ANACLQL 649
            A   LQL
Sbjct: 1136 ARTALQL 1142


>gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]
          Length = 1834

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 112/495 (22%), Positives = 175/495 (35%), Gaps = 75/495 (15%)

Query: 16   EAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPC-------------WFRPGYPE 62
            E +++ E AA +  R L  E+  AGA E +  L   +P              W +    E
Sbjct: 850  EMEEIYEFAATQ--RKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEME 907

Query: 63   AKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPP----GYPEAKKVAEEAAL 118
              +  ++ A      +G    P    + S    A AP    P    G+      + +   
Sbjct: 908  PLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSSPSRDCQA 967

Query: 119  EAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPA----------WPK 168
            E  E  LP    A  +         + S    I +EP+ +  AV             W  
Sbjct: 968  ERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSHRLAPWQA 1027

Query: 169  MVTESCYF---PAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDA 225
                 C F   P Q GS       PR +   SG  +S PR R   +   SP L++    +
Sbjct: 1028 SPPHPCRFLLGPPQGGS-------PRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080

Query: 226  KRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTAT----TSSKRIVRRASLPSLSLKK 281
            K+ R  S    S+  + G Q GK R RS + C+          S  I    S P  S  +
Sbjct: 1081 KQKRDRSILTLSK--EPGHQKGKER-RSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSR 1137

Query: 282  PIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLN 341
                 S   +   V+    L L ++E L+   +K ++      EEK A + SP      +
Sbjct: 1138 SQKSSSKLNEEDEVI----LLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFS 1193

Query: 342  VVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTG 401
            ++     +     PS  P  S A L          +  L EN        R G   LF  
Sbjct: 1194 IIDVDADQ----EPSQSPPRSEAVLQQE------DEGALPENRGSL---GRRGAPWLFCD 1240

Query: 402  QGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGG----RVSQYTC 457
            +   P ++S        T +LV ++    R + C     + + S +  G     V+Q+T 
Sbjct: 1241 RESSPSEAS-----TTDTSWLVPATPLASRSRDCS---SQTQISSLRSGLAVQAVTQHTP 1292

Query: 458  CAAAPGSVGCQVAKQ 472
             A+     G +VA++
Sbjct: 1293 RASVGNREGNEVAQK 1307


>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
           sapiens]
          Length = 459

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 7/128 (5%)

Query: 71  APEA--SRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAP-EFPLPS 127
           AP+A  ++   A  SP G    ++  R T P     G       A E+A  AP   P P+
Sbjct: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171

Query: 128 HQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSACRLP 187
              + S    VP+  + +   +    +P++  P  P A  +  +++   PA R  A R P
Sbjct: 172 DPGSTSSATRVPRARRSSRRAL----QPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRP 227

Query: 188 AAPRLTER 195
            APRL  R
Sbjct: 228 GAPRLLSR 235


>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
           sapiens]
          Length = 459

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 36/128 (28%), Positives = 55/128 (42%), Gaps = 7/128 (5%)

Query: 71  APEA--SRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAP-EFPLPS 127
           AP+A  ++   A  SP G    ++  R T P     G       A E+A  AP   P P+
Sbjct: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171

Query: 128 HQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSACRLP 187
              + S    VP+  + +   +    +P++  P  P A  +  +++   PA R  A R P
Sbjct: 172 DPGSTSSATRVPRARRSSRRAL----QPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRP 227

Query: 188 AAPRLTER 195
            APRL  R
Sbjct: 228 GAPRLLSR 235


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 56/237 (23%), Positives = 90/237 (37%), Gaps = 23/237 (9%)

Query: 61   PEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
            PE K  A  A P  SR   + +    +PEGS    ++      P +P   + A   +  +
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS------PEHPPKSRTARRGSRSS 1675

Query: 121  PEFPLPSH-QPAQSFGLWVPQMHKQA---SAFVDIQAEPQNRGPAVPPAWPKMVTESCYF 176
            PE    S   P +      P++ ++A          + P+ R    PP   +  + S   
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS-RTPPRHRRSPSVSSPE 1734

Query: 177  PAQRGSAC---RLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASS 233
            PA++  +    R  ++PR        R  +P+ R      S        T  +R R  SS
Sbjct: 1735 PAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794

Query: 234  SQRSRGSKVGRQPGK-TRNRSG--------MACKTTATTSSKRIVRRASLPSLSLKK 281
               SR  +  R   + TR R G         A + ++ TSS+R   R+  P  S K+
Sbjct: 1795 QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKR 1851



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 62/244 (25%), Positives = 87/244 (35%), Gaps = 57/244 (23%)

Query: 44  GSKMLRATAPCWFRPGYPEAKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFP 103
           GS    AT P    P  P +     EA+P   R      SP  +PE  K+ ++++    P
Sbjct: 376 GSPQPLATTPLSQEPVNPPS-----EASPTRDR------SPPKSPE--KLPQSSSSESSP 422

Query: 104 PGYPEAKKVAEEAALEAPEFPLP-----SHQPAQSFGLWVPQMHKQASAFVDIQAEPQNR 158
           P  P+  KV+  A+  +PE P P     SH+   S      + H +A         P  R
Sbjct: 423 PS-PQPTKVSRHAS-SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480

Query: 159 -GPAVPPAWPKMVTESCYFPAQRG-SACRLPAAPRLTERPSGVRISAPRKR--------- 207
            G +  PA  K        P +RG S  R P   R        R  +P++R         
Sbjct: 481 MGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRP 540

Query: 208 ------------------KTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKVGRQPGKT 249
                             +  +HS SP        A R R  S +   RG    R P + 
Sbjct: 541 GWSRSRNTQRRGRSRSARRGRSHSRSP--------ATRGRSRSRTPARRGRSRSRTPARR 592

Query: 250 RNRS 253
           R+RS
Sbjct: 593 RSRS 596



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 48/202 (23%), Positives = 71/202 (35%), Gaps = 39/202 (19%)

Query: 64  KKVAKEAAPEASRHLGAEQSPAGAP------EGSKMLRATAPCWFPPGYP--EAKKVAEE 115
           +K A   +P   R     + PA  P       GS    AT P    P  P  EA    + 
Sbjct: 344 EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDR 403

Query: 116 AALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCY 175
           +  ++PE  LP    ++S     P   +         + P++  PA  P           
Sbjct: 404 SPPKSPE-KLPQSSSSESS----PPSPQPTKVSRHASSSPESPKPAPAP----------- 447

Query: 176 FPAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYT----DAKRTRVA 231
                GS   + ++P    R  G      R ++  +HS +P    G +     AKR R  
Sbjct: 448 -----GSHREISSSPTSKNRSHG------RAKRDKSHSHTPSRRMGRSRSPATAKRGRSR 496

Query: 232 SSSQRSRGSKVGRQPGKTRNRS 253
           S +   RG    R P   R+RS
Sbjct: 497 SRTPTKRGHSRSRSPQWRRSRS 518



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 67/296 (22%), Positives = 109/296 (36%), Gaps = 43/296 (14%)

Query: 15   PEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAK---EAA 71
            PE K  A  A    SR     + +  +PEGS    ++      P +P   + A+    ++
Sbjct: 1622 PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS------PEHPPKSRTARRGSRSS 1675

Query: 72   PE---ASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEFPLPSH 128
            PE    SR     +S   +PE ++  R +         PE +         +P    P  
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP-- 1733

Query: 129  QPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPP-----AWPKMVTESCYFPAQRGSA 183
            +PA+       +  + AS+        + R P+  P     +  +   E      +R  +
Sbjct: 1734 EPAEKSR--SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRS 1791

Query: 184  CRLPAAPRLTERP-SGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGSKV 242
                +  R  +R  S  R++  R+  +  HS SP        A++    +SS+R RG   
Sbjct: 1792 GSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP--------ARQESSRTSSRRRRGR-- 1841

Query: 243  GRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVPTVLRR 298
             R P  +R RS      T+    KR   RAS        P   R S  + P + RR
Sbjct: 1842 SRTPPTSRKRSR---SRTSPAPWKRSRSRAS--------PATHRRSRSRTPLISRR 1886



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 19/156 (12%)

Query: 177 PAQRG-SACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGY----TDAKRTRVA 231
           PA+RG S  R PA  R   R       +P +R++   S SP   +G     T A+R R  
Sbjct: 609 PARRGRSRSRTPARRRSRTR-------SPVRRRS--RSRSPARRSGRSRSRTPARRGRSR 659

Query: 232 SSSQRSRGSKVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQ 291
           S +   RG    R P +   RS          S  R  RR    S SL     +R     
Sbjct: 660 SRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL-----VRRGRSH 714

Query: 292 VPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEK 327
             T  RRG     +E   K   S++ +   +  E K
Sbjct: 715 SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMK 750



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 52/242 (21%), Positives = 85/242 (35%), Gaps = 27/242 (11%)

Query: 11   PPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAKEA 70
            PP  P   ++  E A   S  +G   SQ+  P      R+  P  F     +++ +  + 
Sbjct: 2410 PPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSD---QSRCLIAQT 2466

Query: 71   APEA------SRHLGAEQSPAGAPEGSKMLRATAP------CWFPPGYPEAKKVAEEAAL 118
             P A      S  +    S AG   G  ML   AP         PP    A++ +  AAL
Sbjct: 2467 TPVAGSQSLSSGAVATTTSSAGDHNG--MLSVPAPGVPHSDVGEPPASTGAQQPSALAAL 2524

Query: 119  EAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPA 178
            +  +    S   + S           +S+     +   + G ++P   P++  +    P 
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP-VQPEVALKRVPSPT 2583

Query: 179  QRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSR 238
                      AP+   R        P KRK  + SSS    +  + +  +  +SSS  S 
Sbjct: 2584 P---------APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2634

Query: 239  GS 240
             S
Sbjct: 2635 SS 2636


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 71/293 (24%), Positives = 99/293 (33%), Gaps = 34/293 (11%)

Query: 4    ATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEA 63
            AT P    P  P A   + +  L    H G        P   K   AT+P    P  P A
Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315

Query: 64   KKVAKEAAPEASRHLGAEQSPA---GAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEA 120
               + + +P      GA   PA    +P+G+  L AT P     G P      E      
Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS--SKGGPTTPSSKEG---PT 1370

Query: 121  PEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQR 180
            P    PSH+   +     P   K+  A    + +P +  PAV P  PK    +   P  R
Sbjct: 1371 PPAATPSHKGGPAM---TPPSPKRGPAIPSPKGDPTS--PAVIPLSPKKAPAT---PVTR 1422

Query: 181  GSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDAKRTRVASSSQRSRGS 240
              A   P+   LT  P+   +S  +   T A    P   +   D     V   S      
Sbjct: 1423 EGAA-TPSKGDLTP-PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP----- 1475

Query: 241  KVGRQPGKTRNRSGMACKTTATTSSKRIVRRASLPSLSLKKPIILRSSGCQVP 293
                       +   A K  AT+SS +       P  +   P ++ SS  +VP
Sbjct: 1476 -----------KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 28/94 (29%), Positives = 33/94 (35%), Gaps = 2/94 (2%)

Query: 74  ASRHLGAEQSPAGAPEGSKM--LRATAPCWFPPGYPEAKKVAEEAALEAPEFPLPSHQPA 131
           A+ H     SP GAP  S +  L        P   P    V      E P  P P   PA
Sbjct: 851 ATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA 910

Query: 132 QSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPA 165
            S     P+  +   A   I A P  +G   PPA
Sbjct: 911 LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA 944



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 40/159 (25%), Positives = 52/159 (32%), Gaps = 8/159 (5%)

Query: 12   PGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAKEAA 71
            P  P A   + +  L    H G   + A  P   K   AT P    P  P A   + +  
Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 72   PEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALE------APEFPL 125
                   GA  +PA  P   K   AT      P  P A   + +  L       AP  P 
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222

Query: 126  PSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPP 164
             +  P+   GL  P      +        P+  GPA PP
Sbjct: 1223 AT-PPSPKGGLATPSPKGAPTTPAATPPSPKG-GPATPP 1259



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 48/213 (22%), Positives = 66/213 (30%), Gaps = 13/213 (6%)

Query: 4    ATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEA 63
            AT P    P  P A   + +  L      G   + A  P   K   AT P    P  P A
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177

Query: 64   KKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEF 123
               + +         GA  +PA  P   K   AT      P  P A   + +  L     
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT--- 1234

Query: 124  PLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSA 183
              PS + A +     P   K   A       P    P  P A P  +      P  +G+ 
Sbjct: 1235 --PSPKGAPTTPAATPPSPKGGPA-----TPPPKGAPTPPAATPPSLKGGLATPPHKGAP 1287

Query: 184  CRLPAAPRLTERPSGVRISAPRKRKTIAHSSSP 216
                  P     P G   ++P K      +++P
Sbjct: 1288 NPAVVTP---PSPKGGPATSPPKGAPTPPAATP 1317



 Score = 29.6 bits (65), Expect = 9.5
 Identities = 49/213 (23%), Positives = 66/213 (30%), Gaps = 24/213 (11%)

Query: 4    ATAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEA 63
            AT P   P G P A  + + A    +  L    S  G P    +  A  P       P A
Sbjct: 1038 ATPPS--PKGSPAATPLPKGAPTTPAATL---PSPKGGPATPSLKGAPTP-------PAA 1085

Query: 64   KKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEF 123
               + +  P      GA   PA  P   K   AT P    P  P A   + +  L  P  
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145

Query: 124  PLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSA 183
                  PA +     P   K   A       P    P  P A P         P+ +G+ 
Sbjct: 1146 KGAPTTPAAT-----PPSPKGGLA-----TPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195

Query: 184  CRLPAAPRLTERPSGVRISAPRKRKTIAHSSSP 216
                A P       G+   +P+   T   ++ P
Sbjct: 1196 TTPAATP--PSPKGGLATPSPKGAPTTPAATPP 1226


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 37.0 bits (84), Expect = 0.060
 Identities = 46/181 (25%), Positives = 65/181 (35%), Gaps = 8/181 (4%)

Query: 27  EASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAKEAAPEASRHLGAEQSPAG 86
           EASR L     +  A    + L  + P    P  P  ++      PE+S     E+SP  
Sbjct: 463 EASR-LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521

Query: 87  APEGSKMLRATAPCWFPPGYPEAKKVA---EEAALEAPEFPLPSHQPAQSFGLWVPQMHK 143
            PE S    A      PP  PEA  ++   EE+ L  P   LP+  P ++  L  P    
Sbjct: 522 PPEESPPSPALETPLSPP--PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579

Query: 144 QASAFVDIQAEPQNRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISA 203
             S     +  P +  P     +P         P +       P A RL+  P    +S 
Sbjct: 580 PMSP--PPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637

Query: 204 P 204
           P
Sbjct: 638 P 638


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 36.6 bits (83), Expect = 0.078
 Identities = 42/163 (25%), Positives = 58/163 (35%), Gaps = 9/163 (5%)

Query: 5   TAPCWFPPGYPEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPCWFRPGYPEAK 64
           TAP   PPG P A    + A   + R   G Q + G P   K   +  P           
Sbjct: 267 TAPA--PPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRP-ADKDAASCGPGAAVAAVERGA 323

Query: 65  KVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEFP 124
               +A+P +   L ++  P      +    A A   F PG P     A    +    F 
Sbjct: 324 AGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLP----CAPRTLIGKGHFL 379

Query: 125 LPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPAWP 167
           L  +   Q  G  VPQ   +  A ++   +     PAVPPA P
Sbjct: 380 L--YPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPP 420


>gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isoform
           2 [Homo sapiens]
          Length = 1562

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 15/102 (14%)

Query: 33  GGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAKEAAPEASRHLGA------------ 80
           GG   +AG  EG ++++          + E  K+ K  A  A   LG+            
Sbjct: 75  GGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSMGISGLQQ 134

Query: 81  EQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPE 122
           + SPAGAP  + ++ +  P   PP  P  +++     L+ PE
Sbjct: 135 DPSPAGAPRITSVIPSPPP---PPPLPPPQRITGPKPLQDPE 173


>gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isoform
           1 [Homo sapiens]
          Length = 1522

 Score = 36.2 bits (82), Expect = 0.10
 Identities = 26/102 (25%), Positives = 43/102 (42%), Gaps = 15/102 (14%)

Query: 33  GGEQSQAGAPEGSKMLRATAPCWFRPGYPEAKKVAKEAAPEASRHLGA------------ 80
           GG   +AG  EG ++++          + E  K+ K  A  A   LG+            
Sbjct: 75  GGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVVKLIKSGAYVALTLLGSSPSSMGISGLQQ 134

Query: 81  EQSPAGAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPE 122
           + SPAGAP  + ++ +  P   PP  P  +++     L+ PE
Sbjct: 135 DPSPAGAPRITSVIPSPPP---PPPLPPPQRITGPKPLQDPE 173


>gi|37693995 Kruppel-like factor 13 [Homo sapiens]
          Length = 288

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 81  EQSPAGAP----EGSKMLRATAPCWFPPGYPEAKKVAEEAALEAPEFPLPSHQPAQSFGL 136
           +Q+PA AP    EG+   +A  PC  PP  PE      E A  AP  P  S +P    GL
Sbjct: 73  QQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSPAWS-EPEPEAGL 131


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 35.0 bits (79), Expect = 0.23
 Identities = 73/279 (26%), Positives = 102/279 (36%), Gaps = 54/279 (19%)

Query: 16   EAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAP-CWFRPGY--------PEAKKV 66
            E + + EEAA E    L      A AP     LR  A      PG+        P   + 
Sbjct: 6920 EHRVLEEEAAREEQATL-----LAKAPSFETALRLPASGTHLAPGHSHSLEHDSPSTPRP 6974

Query: 67   AKEAAPEASRHLGAEQSPA-----GAPEGSKMLRATAPCWFPPGYPEAKKVAEEAALEAP 121
            + EA  EA R   A    A     G P+GSK L +T       G+P        A  E P
Sbjct: 6975 SSEACGEAQRLPSAPSGGAPIRDMGHPQGSKQLPSTG------GHPGT------AQPERP 7022

Query: 122  EFPLPSHQPAQSFGLWVPQMH-KQASAFVDIQAEPQNRGPAVPPAWPK-------MVTES 173
                P  QPA       P  H KQ SA  +  +      P  P ++P        +V  S
Sbjct: 7023 SPDSPWGQPA-------PFCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSS 7075

Query: 174  CYFPAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGY-TDAKRTRVAS 232
             +    +       A+P L  +     IS P + K       PC   G  + A  ++V  
Sbjct: 7076 PFLGQPQAPPAPAKASPPLDSKMGPGDISLPGRPKP-----GPCSSPGSASQASSSQV-- 7128

Query: 233  SSQRSRGSKVGRQPGKTRNRSGMACKTTATTSSKRIVRR 271
            SS R   S+VG +PG + +  G   +    + S   ++R
Sbjct: 7129 SSLRVGSSQVGTEPGPSLDAEGWTQEAEDLSDSTPTLQR 7167



 Score = 30.0 bits (66), Expect = 7.3
 Identities = 33/116 (28%), Positives = 43/116 (37%), Gaps = 11/116 (9%)

Query: 15   PEAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATA--PCWFRPGYPEAKKVAKEAAP 72
            P ++   E   L ++   G      G P+GSK L +T   P   +P  P       + AP
Sbjct: 6974 PSSEACGEAQRLPSAPSGGAPIRDMGHPQGSKQLPSTGGHPGTAQPERPSPDSPWGQPAP 7033

Query: 73   EASRHLGAEQSPAGAPEGSKMLRATAPC---WFPPG-YPEAKKVAEEAALEAPEFP 124
                  G     +   EG     A APC    FPPG   EA  V     L  P+ P
Sbjct: 7034 FCHPKQG-----SAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAP 7084


>gi|14602439 Williams Beuren syndrome chromosome region 14 isoform
           delta [Homo sapiens]
          Length = 831

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 42/156 (26%), Positives = 55/156 (35%), Gaps = 22/156 (14%)

Query: 99  PCWFPPGYPEAKKVA--EEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQ 156
           PC  PP  P A   A  +E  L +P FP P+  PA               A       PQ
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV--------SPLPAPAAFPPTPQ 460

Query: 157 NRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISAP------RKRKTI 210
           +     P  +P  +    Y     G    +P        P G + S P          T 
Sbjct: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520

Query: 211 AHSSSPCLVTGYTDAKRTR------VASSSQRSRGS 240
           A S++PCL    T AK  +      V+S+  RS GS
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS 556


>gi|14602437 Williams Beuren syndrome chromosome region 14 isoform
           gamma [Homo sapiens]
          Length = 850

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 42/156 (26%), Positives = 55/156 (35%), Gaps = 22/156 (14%)

Query: 99  PCWFPPGYPEAKKVA--EEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQ 156
           PC  PP  P A   A  +E  L +P FP P+  PA               A       PQ
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV--------SPLPAPAAFPPTPQ 460

Query: 157 NRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISAP------RKRKTI 210
           +     P  +P  +    Y     G    +P        P G + S P          T 
Sbjct: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520

Query: 211 AHSSSPCLVTGYTDAKRTR------VASSSQRSRGS 240
           A S++PCL    T AK  +      V+S+  RS GS
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS 556


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 42/156 (26%), Positives = 55/156 (35%), Gaps = 22/156 (14%)

Query: 99  PCWFPPGYPEAKKVA--EEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQ 156
           PC  PP  P A   A  +E  L +P FP P+  PA               A       PQ
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV--------SPLPAPAAFPPTPQ 460

Query: 157 NRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISAP------RKRKTI 210
           +     P  +P  +    Y     G    +P        P G + S P          T 
Sbjct: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520

Query: 211 AHSSSPCLVTGYTDAKRTR------VASSSQRSRGS 240
           A S++PCL    T AK  +      V+S+  RS GS
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS 556


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 34.7 bits (78), Expect = 0.30
 Identities = 42/156 (26%), Positives = 55/156 (35%), Gaps = 22/156 (14%)

Query: 99  PCWFPPGYPEAKKVA--EEAALEAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQ 156
           PC  PP  P A   A  +E  L +P FP P+  PA               A       PQ
Sbjct: 409 PCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPPAPGV--------SPLPAPAAFPPTPQ 460

Query: 157 NRGPAVPPAWPKMVTESCYFPAQRGSACRLPAAPRLTERPSGVRISAP------RKRKTI 210
           +     P  +P  +    Y     G    +P        P G + S P          T 
Sbjct: 461 SVPSPAPTPFPIELLPLGYSEPAFGPCFSMPRGKPPAPSPRGQKASPPTLAPATASPPTT 520

Query: 211 AHSSSPCLVTGYTDAKRTR------VASSSQRSRGS 240
           A S++PCL    T AK  +      V+S+  RS GS
Sbjct: 521 AGSNNPCLTQLLTAAKPEQALEPPLVSSTLLRSPGS 556


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,268,932
Number of Sequences: 37866
Number of extensions: 1454005
Number of successful extensions: 5213
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 98
Number of HSP's that attempted gapping in prelim test: 5043
Number of HSP's gapped (non-prelim): 242
length of query: 675
length of database: 18,247,518
effective HSP length: 109
effective length of query: 566
effective length of database: 14,120,124
effective search space: 7991990184
effective search space used: 7991990184
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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