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Search of human proteins with 116284396
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
(2003 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 3848 0.0
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 3831 0.0
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 3827 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 2605 0.0
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 2536 0.0
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 2463 0.0
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 2458 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 2457 0.0
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 2452 0.0
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 1316 0.0
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1305 0.0
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1305 0.0
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 1305 0.0
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 1301 0.0
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 1298 0.0
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 1298 0.0
gi|156104908 myosin heavy chain 6 [Homo sapiens] 1295 0.0
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 1285 0.0
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 1258 0.0
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 1152 0.0
gi|122937345 myosin VB [Homo sapiens] 557 e-158
gi|153945715 myosin VC [Homo sapiens] 546 e-155
gi|215982794 myosin VA isoform 2 [Homo sapiens] 543 e-154
gi|215982791 myosin VA isoform 1 [Homo sapiens] 541 e-153
gi|28416946 myosin 18A isoform a [Homo sapiens] 533 e-151
gi|42794779 myosin 18A isoform b [Homo sapiens] 528 e-149
gi|154354979 myosin X [Homo sapiens] 476 e-133
gi|118402590 myosin XV [Homo sapiens] 457 e-128
gi|122937512 myosin VIIB [Homo sapiens] 456 e-128
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 453 e-127
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 3848 bits (9979), Expect = 0.0
Identities = 2003/2003 (100%), Positives = 2003/2003 (100%)
Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
Query: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
Query: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
Query: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
Query: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
Query: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
Query: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
Query: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS 660
DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS
Sbjct: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS 660
Query: 661 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 720
LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV
Sbjct: 661 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 720
Query: 721 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 780
LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE
Sbjct: 721 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 780
Query: 781 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA 840
LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA
Sbjct: 781 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA 840
Query: 841 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 900
LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV
Sbjct: 841 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 900
Query: 901 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 960
GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE
Sbjct: 901 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 960
Query: 961 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1020
ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS
Sbjct: 961 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1020
Query: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1080
KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK
Sbjct: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1080
Query: 1081 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1140
LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE
Sbjct: 1081 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1140
Query: 1141 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1200
AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE
Sbjct: 1141 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1200
Query: 1201 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1260
VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE
Sbjct: 1201 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1260
Query: 1261 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1320
LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA
Sbjct: 1261 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1320
Query: 1321 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380
LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE
Sbjct: 1321 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380
Query: 1381 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1440
AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV
Sbjct: 1381 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1440
Query: 1441 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1500
DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE
Sbjct: 1441 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1500
Query: 1501 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR 1560
AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR
Sbjct: 1501 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR 1560
Query: 1561 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1620
VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA
Sbjct: 1561 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1620
Query: 1621 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680
KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK
Sbjct: 1621 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680
Query: 1681 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1740
ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD
Sbjct: 1681 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1740
Query: 1741 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800
EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA
Sbjct: 1741 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800
Query: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1860
ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR
Sbjct: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1860
Query: 1861 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1920
ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR
Sbjct: 1861 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1920
Query: 1921 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1980
AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE
Sbjct: 1921 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1980
Query: 1981 AEEAQPGSGPSPEPEGSPPAHPQ 2003
AEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1981 AEEAQPGSGPSPEPEGSPPAHPQ 2003
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 3831 bits (9935), Expect = 0.0
Identities = 2003/2036 (98%), Positives = 2003/2036 (98%), Gaps = 33/2036 (1%)
Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG
Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
Query: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
Query: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
Query: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
Query: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
Query: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
Query: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
Query: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------ 648
DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD
Sbjct: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660
Query: 649 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 687
VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS
Sbjct: 661 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720
Query: 688 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 747
RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ
Sbjct: 721 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780
Query: 748 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 807
EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER
Sbjct: 781 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840
Query: 808 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 867
DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK
Sbjct: 841 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900
Query: 868 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 927
PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL
Sbjct: 901 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960
Query: 928 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 987
CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE
Sbjct: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020
Query: 988 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1047
EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV
Sbjct: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080
Query: 1048 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1107
KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR
Sbjct: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140
Query: 1108 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1167
AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR
Sbjct: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200
Query: 1168 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1227
DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG
Sbjct: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260
Query: 1228 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1287
QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ
Sbjct: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320
Query: 1288 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1347
EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE
Sbjct: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380
Query: 1348 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1407
LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE
Sbjct: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440
Query: 1408 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1467
EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL
Sbjct: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500
Query: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527
VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL
Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
Query: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1587
ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK
Sbjct: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620
Query: 1588 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1647
LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL
Sbjct: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680
Query: 1648 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1707
EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL
Sbjct: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740
Query: 1708 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1767
KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE
Sbjct: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800
Query: 1768 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1827
EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG
Sbjct: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860
Query: 1828 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1887
EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER
Sbjct: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920
Query: 1888 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1947
RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT
Sbjct: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980
Query: 1948 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2003
TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 3827 bits (9924), Expect = 0.0
Identities = 1995/2003 (99%), Positives = 1995/2003 (99%), Gaps = 8/2003 (0%)
Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS
Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60
Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS
Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120
Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG
Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180
Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240
AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP G
Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G 232
Query: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300
ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI
Sbjct: 233 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292
Query: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360
RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL
Sbjct: 293 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 352
Query: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420
RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS
Sbjct: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412
Query: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480
RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS
Sbjct: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 472
Query: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540
FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL
Sbjct: 473 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 532
Query: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600
DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA
Sbjct: 533 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 592
Query: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS 660
DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS
Sbjct: 593 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS 652
Query: 661 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 720
LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV
Sbjct: 653 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 712
Query: 721 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 780
LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE
Sbjct: 713 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 772
Query: 781 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA 840
LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA
Sbjct: 773 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA 832
Query: 841 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 900
LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV
Sbjct: 833 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 892
Query: 901 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 960
GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE
Sbjct: 893 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 952
Query: 961 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1020
ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS
Sbjct: 953 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1012
Query: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1080
KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK
Sbjct: 1013 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1072
Query: 1081 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1140
LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE
Sbjct: 1073 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1132
Query: 1141 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1200
AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE
Sbjct: 1133 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1192
Query: 1201 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1260
VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE
Sbjct: 1193 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1252
Query: 1261 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1320
LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA
Sbjct: 1253 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1312
Query: 1321 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380
LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE
Sbjct: 1313 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1372
Query: 1381 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1440
AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV
Sbjct: 1373 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1432
Query: 1441 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1500
DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE
Sbjct: 1433 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1492
Query: 1501 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR 1560
AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR
Sbjct: 1493 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR 1552
Query: 1561 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1620
VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA
Sbjct: 1553 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1612
Query: 1621 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680
KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK
Sbjct: 1613 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1672
Query: 1681 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1740
ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD
Sbjct: 1673 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1732
Query: 1741 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800
EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA
Sbjct: 1733 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1792
Query: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1860
ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR
Sbjct: 1793 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1852
Query: 1861 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1920
ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR
Sbjct: 1853 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1912
Query: 1921 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1980
AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE
Sbjct: 1913 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1972
Query: 1981 AEEAQPGSGPSPEPEGSPPAHPQ 2003
AEEAQPGSGPSPEPEGSPPAHPQ
Sbjct: 1973 AEEAQPGSGPSPEPEGSPPAHPQ 1995
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 2605 bits (6751), Expect = 0.0
Identities = 1312/1956 (67%), Positives = 1622/1956 (82%), Gaps = 15/1956 (0%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +WTA++LVW+PSE HGFEAA++++E +E VELAE+G++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK
Sbjct: 87 VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK
Sbjct: 147 RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ +P GELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DHNIP--------GELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE ++YRFL+NG P
Sbjct: 259 ANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIP 318
Query: 347 GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
GQ+ ++ FQET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT A
Sbjct: 319 GQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVA 378
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QKLC LLG+ V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV
Sbjct: 379 QKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVH 438
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALDR+ RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439 RINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG
Sbjct: 499 YQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQG 558
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
H KFQ+PR L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR AE+
Sbjct: 559 SHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAEL 618
Query: 646 WKDVEGIVGLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
WKDV+ IVGL+QV+ + + G + ++GMFRTVGQLYKESL++LMATL NTNP+FVRC
Sbjct: 619 WKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRC 678
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PNHEKRAGKL+P LVLDQLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEILTPNAIPK
Sbjct: 679 IIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPK 738
Query: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
GFMDGKQACE+MI+ALELDPNLYR+GQSKIFFRAGVLA LEEERDLK+TDII+ FQA R
Sbjct: 739 GFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCR 798
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
GYLAR+AF K+QQQ SAL+V+QRNCAAYLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+
Sbjct: 799 GYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKD 858
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
+EL KV+E Q + E+ E++ + QL EE+ LAEQL+AE EL AEAEE R RLAA+KQ
Sbjct: 859 EELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQ 918
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
ELE ++ +LE+RV EEEE ++ +Q EKK++Q HIQ+LE L+ EEGARQKLQLEKVT EA
Sbjct: 919 ELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEA 978
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+KK EE++LLLEDQNSK KE+KL+EDR+AE SSQ AEEEEK K+L K+R K E I+D
Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E+RL+KEEK RQELEK KR+LDGE+++LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR
Sbjct: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
+DE + LK +RE QA +AE QED ESE+ +R KAEKQ+RDL EELEAL+ ELEDT
Sbjct: 1099 GDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDT 1158
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
LD+T AQQELR+KREQEV ELKK LEEET+ HEA +Q++RQRH AL EL+EQLEQA+R
Sbjct: 1159 LDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K EK + LE + EL E+ LQ + E E +R++L+ Q+QE+ + +G+R R E
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVEL 1278
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
AEK + Q EL+NVS L EAE K I+ +K+ +S E+QL D QELLQEETR KL L SR+
Sbjct: 1279 AEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRI 1338
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
R +E E L+EQ EEE AR+ +++ Q+QL++ +++ +++ G +E+ EEA+++
Sbjct: 1339 RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLL 1398
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
++AEAL+QRL EK D+LE+ + RLQQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLA
Sbjct: 1399 KDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLA 1458
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
EEK+ R EER+RAEAE RE+E +ALSL RALEE EA+EE ERQN+ LRA++E L+S
Sbjct: 1459 EEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMS 1518
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
SKDDVGK+VHELE++ R EQ ++R Q+ ELEDEL A EDAKLRLEV +QA+K Q ER
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
DLQ RDE EE++R L KQ+R+ E E ++ERKQR LAVA++KK+E +L++L+AQ+ +A +
Sbjct: 1579 DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
++E +KQLRK+QAQMK+ RE+EE R SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELAS 1698
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
S+RARR A+Q+RDE+ADE+ N K+A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR
Sbjct: 1699 SERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDR 1758
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
+RK LQV++L EL+AERS + K+++ RQQLERQ +EL+ +L E + +++ K TI+A
Sbjct: 1759 FRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISA 1818
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+K+ Q EEQLEQE +ER + KLVRR EK+LKE+ +QVE+ERR ADQ ++Q+EK N R
Sbjct: 1819 LEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANAR 1878
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR-GPLTF-T 1961
+KQLKRQLEEAEEEA+RA A RR+LQREL+D TE+ E ++REV+TL+NRLRR GP++F +
Sbjct: 1879 MKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSS 1938
Query: 1962 TRTVRQVFRLEEG--VASDEEAEEAQPGSGPSPEPE 1995
+R+ R+ LE SD++ E + P+
Sbjct: 1939 SRSGRRQLHLEGASLELSDDDTESKTSDVNETQPPQ 1974
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 2536 bits (6572), Expect = 0.0
Identities = 1267/1949 (65%), Positives = 1589/1949 (81%), Gaps = 16/1949 (0%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A++LVWVPS+ GFE A+L++E EEA VEL E+G+++++ +D IQ+MNPPKFSK
Sbjct: 23 QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK
Sbjct: 83 VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K
Sbjct: 143 RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ G ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 203 DQG-----------ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVG 251
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG + P
Sbjct: 252 ANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIP 311
Query: 347 GQE-RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
GQ+ +++FQET+E++R++G EE + +LR++S VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 312 GQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAA 371
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+ LLG+ VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVL
Sbjct: 372 QKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVL 431
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 432 RINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEE 491
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG
Sbjct: 492 YQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQG 551
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+ +E+
Sbjct: 552 THPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSEL 611
Query: 646 WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
WKDV+ I+GL+QV+ + + P + R+GMFRTVGQLYKE L++LMATL NTNP+FVRC
Sbjct: 612 WKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRC 671
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PNHEK+AGKL+P LVLDQLRCNGVLEGIRICRQGFPNR++FQEFRQRYEILTPN+IPK
Sbjct: 672 IIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPK 731
Query: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
GFMDGKQAC MI+ALELD NLYR+GQSK+FFRAGVLA LEEERDLK+TD+I+ FQA R
Sbjct: 732 GFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCR 791
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+
Sbjct: 792 GYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKE 851
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
+EL KV+E Q + + E++ +QL E+ +L EQL+AE ELCAEAEE R RL A+KQ
Sbjct: 852 EELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQ 911
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
ELE + +LEARV EEEE + +Q EKK++QQ+IQELE LE EE ARQKLQLEKVTTEA
Sbjct: 912 ELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEA 971
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+KK EE+ ++LEDQN KL+KE+KLLEDR+AEF++ EEEEK KSL KL+ K+EA I D
Sbjct: 972 KLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD 1031
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E+RLR+EEK RQELEK +R+L+G+S++L +Q+ E Q + EL+ QL +KEEELQAALAR
Sbjct: 1032 LEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALAR 1091
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
E+E + LK +RE ++ ++E QEDLESER +R KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
LDST AQQELRSKREQEV LKKTLEEE + HEA +QE+RQ+H QA+ ELAEQLEQ +R
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K EK + LE E EL E+ L + + E +R+++E QLQE+Q + +GER R E
Sbjct: 1212 KANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTEL 1271
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
A+K+ + Q EL+NV+G L++++SK+ +L+K+ S+ E+QL D QELLQEE R KL+L +++
Sbjct: 1272 ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKL 1331
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
+ +E E REQLEEE A+ +++ T AQ+++ +++ E+ G LE EE +R+
Sbjct: 1332 KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQ 1391
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
++ E L+QR EK D+LE+ + RLQQELDD +DL+ QRQ LEKKQ+KFDQLLA
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA 1451
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
EEK + EER+RAEAE RE+E +ALSL RALEE E + ELER N+ R E+E L+S
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMS 1511
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
SKDDVGKSVHELE++ R EQ +++ Q+ ELEDEL A EDAKLRLEV +QA+K Q ER
Sbjct: 1512 SKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFER 1571
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
DLQGRDE EE+++QL +Q+R+ E E ++ERKQR++AVAARKKLE +L++L+A + SA +
Sbjct: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANK 1631
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
++EA+KQLRK+QAQMK+ RE+++TR SREEI +Q +E+EK+LK +EAE+++LQEELAA
Sbjct: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAA 1691
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++RA+RQAQQ+RDE+ADE+AN + A LEEKR+LE R+ QLEEELEEEQ N+EL+NDR
Sbjct: 1692 AERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR 1751
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
+K LQ++ + T+L+ ERS + K E+ RQQLERQ +EL+ +L E + ++++K +I A
Sbjct: 1752 LKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITA 1811
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+K+AQ EEQL+ ET+ER + K VRR EK+LK+V+LQV++ERR A+Q +DQ +K + R
Sbjct: 1812 LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTR 1871
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTR 1963
+KQLKRQLEEAEEEA RA A RR+LQRELED TE+A++MNREV++L+N+LRRG L F
Sbjct: 1872 LKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFV-- 1929
Query: 1964 TVRQVFRLEEGVASDEEAEEAQPGSGPSP 1992
R++ R G SDEE + G+ P
Sbjct: 1930 VPRRMARKGAGDGSDEEVDGKADGAEAKP 1958
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 2463 bits (6383), Expect = 0.0
Identities = 1236/1941 (63%), Positives = 1576/1941 (81%), Gaps = 6/1941 (0%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + S +YGELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSITQGPS-FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 265
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 266 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 325
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 385
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 386 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 566 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 646 WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
WKDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRC
Sbjct: 626 WKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRC 685
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPK
Sbjct: 686 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 745
Query: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
GFMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA R
Sbjct: 746 GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 805
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+
Sbjct: 806 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQ
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 925
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
ELE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EA
Sbjct: 926 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 985
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I++
Sbjct: 986 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
+DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1106 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1165
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
LDST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R
Sbjct: 1166 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1225
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE
Sbjct: 1226 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
+K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
R +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
EEK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+S
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
SKDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ER
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
DLQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
G+EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAA
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN R
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTR 1963
VKQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LRRG T
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1945
Query: 1964 TVRQVFR--LEEGVASDEEAE 1982
+ R R +E S+EE +
Sbjct: 1946 SRRSGGRRVIENADGSEEETD 1966
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 2458 bits (6370), Expect = 0.0
Identities = 1228/1914 (64%), Positives = 1564/1914 (81%), Gaps = 4/1914 (0%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + S +YGELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSITQGPS-FAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 265
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 266 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 325
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 326 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 385
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 386 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 445
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 446 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 505
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 506 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 565
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 566 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 625
Query: 646 WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
WKDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRC
Sbjct: 626 WKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRC 685
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPK
Sbjct: 686 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 745
Query: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
GFMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA R
Sbjct: 746 GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 805
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+
Sbjct: 806 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 865
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQ
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 925
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
ELE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EA
Sbjct: 926 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 985
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I++
Sbjct: 986 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1105
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
+DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1106 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1165
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
LDST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R
Sbjct: 1166 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1225
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE
Sbjct: 1226 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1285
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
+K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++
Sbjct: 1286 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1345
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
R +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R
Sbjct: 1346 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1405
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLA
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
EEK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+S
Sbjct: 1466 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1525
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
SKDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ER
Sbjct: 1526 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1585
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
DLQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +
Sbjct: 1586 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1645
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
G+EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1765
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAA
Sbjct: 1766 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1825
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN R
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1957
VKQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LR P
Sbjct: 1886 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1939
Score = 196 bits (499), Expect = 1e-49
Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%)
Query: 1109 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1161
Q+ R+EEE+QA L + ++ LK L + + L E QE L++E +
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912
Query: 1162 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
AE+ R ++L E L + LE+ D Q R K Q++ +L++ LEEE
Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 969
Query: 1215 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1271
EAA Q+L+ A + +L +++ K R LE +S+L L+ +
Sbjct: 970 -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028
Query: 1272 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1331
+ + + + E + E++ R E++R E + ++ + + + + + +++ L
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088
Query: 1332 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1391
+L+ E +L A L +E K ++R +E + L+E L+ E AAR +A ++
Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148
Query: 1392 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1450
+ +L + E+ + +E R + +E L + L E+T + + +++ R++
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208
Query: 1451 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1510
Q +++ T LEQ ++ + L+K ++ ++ A+ + + ++ E + ++ EA+
Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268
Query: 1511 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1569
L + + AR EL + L+ E+E++ ++ GK++ + A D+
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1317
Query: 1570 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1627
+ ++L+D + E+ + +L V+ + + + ER+ LQ + + E ++ L + +
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 1628 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680
++ D ++K + A +K+ + E+E L Q ++ K ++Q ++
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 1681 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1739
+L +++ R ++ S + +++ L AE + + A DRA +A++ ++ A
Sbjct: 1438 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1492
Query: 1740 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1792
+A L +A LE K +LE L+ E+E+ S N L R L Q+E
Sbjct: 1493 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549
Query: 1793 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1851
+ T+L E + +LE +Q L+G+ E D AR +++ L+ +L +
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1608
Query: 1852 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1911
E +LE E ++R L+ ++ E LK++ LQ + + ++ QL K ++K +R+L
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668
Query: 1912 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1957
E+A E++A +A +LQ +L + + + E L L
Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1727
Query: 1958 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1988
L+ + RLE +A EE E + G+
Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1758
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 2457 bits (6368), Expect = 0.0
Identities = 1234/1941 (63%), Positives = 1573/1941 (81%), Gaps = 13/1941 (0%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 259 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 319 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 379 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 499 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 559 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
Query: 646 WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
WKDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRC
Sbjct: 619 WKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRC 678
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPK
Sbjct: 679 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 738
Query: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
GFMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA R
Sbjct: 739 GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 798
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+
Sbjct: 799 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQ
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
ELE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EA
Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I++
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
+DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1158
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
LDST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R
Sbjct: 1159 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1218
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE
Sbjct: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
+K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
R +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLA
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
EEK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+S
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
SKDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ER
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
DLQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
G+EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAA
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN R
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTR 1963
VKQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LRRG T
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVP 1938
Query: 1964 TVRQVFR--LEEGVASDEEAE 1982
+ R R +E S+EE +
Sbjct: 1939 SRRSGGRRVIENADGSEEETD 1959
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 2452 bits (6355), Expect = 0.0
Identities = 1226/1914 (64%), Positives = 1561/1914 (81%), Gaps = 11/1914 (0%)
Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106
Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK
Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86
Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166
EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK
Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146
Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226
RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K
Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206
Query: 227 EPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
+ + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVG
Sbjct: 207 DTSIT--------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVG 258
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 346
ANIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P
Sbjct: 259 ANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIP 318
Query: 347 G-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAA
Sbjct: 319 AAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAA 378
Query: 406 QKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVL 465
QK+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++
Sbjct: 379 QKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILT 438
Query: 466 RLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEE 525
R+N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEE
Sbjct: 439 RVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEE 498
Query: 526 YQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQG 585
YQREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG
Sbjct: 499 YQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG 558
Query: 586 GHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++
Sbjct: 559 SHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADL 618
Query: 646 WKDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
WKDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRC
Sbjct: 619 WKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRC 678
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPK
Sbjct: 679 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPK 738
Query: 764 GFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
GFMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA R
Sbjct: 739 GFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCR 798
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
GYLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+
Sbjct: 799 GYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKE 858
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQ
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQ 918
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
ELE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EA
Sbjct: 919 ELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEA 978
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I++
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALAR 1098
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
+DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDT
Sbjct: 1099 LDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT 1158
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
LDST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R
Sbjct: 1159 LDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA 1218
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE
Sbjct: 1219 KANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAEL 1278
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
+K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++
Sbjct: 1279 NDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAA 1423
R +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLA
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1458
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
EEK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+S
Sbjct: 1459 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 1518
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
SKDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ER
Sbjct: 1519 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 1578
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
DLQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +
Sbjct: 1579 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 1638
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
G+EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDR 1758
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAA
Sbjct: 1759 VRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAA 1818
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN R
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1957
VKQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LR P
Sbjct: 1879 VKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1932
Score = 196 bits (499), Expect = 1e-49
Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%)
Query: 1109 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1161
Q+ R+EEE+QA L + ++ LK L + + L E QE L++E +
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905
Query: 1162 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
AE+ R ++L E L + LE+ D Q R K Q++ +L++ LEEE
Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962
Query: 1215 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1271
EAA Q+L+ A + +L +++ K R LE +S+L L+ +
Sbjct: 963 -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021
Query: 1272 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1331
+ + + + E + E++ R E++R E + ++ + + + + + +++ L
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081
Query: 1332 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1391
+L+ E +L A L +E K ++R +E + L+E L+ E AAR +A ++
Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141
Query: 1392 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1450
+ +L + E+ + +E R + +E L + L E+T + + +++ R++
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201
Query: 1451 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1510
Q +++ T LEQ ++ + L+K ++ ++ A+ + + ++ E + ++ EA+
Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261
Query: 1511 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1569
L + + AR EL + L+ E+E++ ++ GK++ + A D+
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1310
Query: 1570 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1627
+ ++L+D + E+ + +L V+ + + + ER+ LQ + + E ++ L + +
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 1628 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680
++ D ++K + A +K+ + E+E L Q ++ K ++Q ++
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 1681 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1739
+L +++ R ++ S + +++ L AE + + A DRA +A++ ++ A
Sbjct: 1431 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1485
Query: 1740 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1792
+A L +A LE K +LE L+ E+E+ S N L R L Q+E
Sbjct: 1486 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542
Query: 1793 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1851
+ T+L E + +LE +Q L+G+ E D AR +++ L+ +L +
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1601
Query: 1852 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1911
E +LE E ++R L+ ++ E LK++ LQ + + ++ QL K ++K +R+L
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661
Query: 1912 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1957
E+A E++A +A +LQ +L + + + E L L
Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1720
Query: 1958 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1988
L+ + RLE +A EE E + G+
Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 1316 bits (3405), Expect = 0.0
Identities = 735/1913 (38%), Positives = 1154/1913 (60%), Gaps = 38/1913 (1%)
Query: 56 VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113
V+VP + F A + R+ G+ AE E G+ + + DQ+ + NPPKF K EDMA L
Sbjct: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93
Query: 114 TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173
T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT +V YRGKKR E PPH
Sbjct: 94 TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153
Query: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPAS 233
++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K+ P
Sbjct: 154 IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213
Query: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 214 ------GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 267
Query: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
LEKSR I Q K E +HIFYQ+L +L LL+ + Y F++ G ++ + E
Sbjct: 268 LEKSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAE 327
Query: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
T + VLGF+ EE SM ++ A++ FGN+ K ++ +QA A K L
Sbjct: 328 ELMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYL 387
Query: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
+GL D + L PR+KVG +YV K Q +Q +A ALAKA YER+F W+V R+N L
Sbjct: 388 MGLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATL 447
Query: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 448 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 505
Query: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 506 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSAN 562
Query: 590 FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V L +S+ +L + ++
Sbjct: 563 FQKPRNIKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFA 622
Query: 648 DVEGIVGLEQVSSLGDGP---PGGRPRRGM-FRTVGQLYKESLSRLMATLSNTNPSFVRC 703
+ G D P G+ ++G F+TV L++E+L++LM L +T+P FVRC
Sbjct: 623 NYAG----------ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRC 672
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PN K G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+
Sbjct: 673 IIPNETKSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPE 732
Query: 764 G-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 822
G F+D ++ EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA +
Sbjct: 733 GQFIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQS 792
Query: 823 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 882
RG LAR ++K +++ +L V+Q N A++ +++W W +L+ K+KPLL+ +++ + +
Sbjct: 793 RGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASM 852
Query: 883 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 942
+E +++E ++S EL+ ++ L +E+ L Q++AE + A+AEE +L K
Sbjct: 853 KEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNK 912
Query: 943 QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1002
+LE V E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE
Sbjct: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 1003 AKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIA 1062
K+K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E +
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVD 1032
Query: 1063 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
D+E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ EL A A
Sbjct: 1033 DLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNA 1092
Query: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182
R EDE +QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+
Sbjct: 1093 RIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEE 1152
Query: 1183 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242
+T+ Q E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R
Sbjct: 1153 AGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR 1212
Query: 1243 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1302
K EK + + E+ ++ + + + A+ E+ R LE Q+ E + +A + +R+ +
Sbjct: 1213 VKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVND 1272
Query: 1303 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
+ + Q E +S L+E E+ +L++ + QL D + L+EE +AK AL
Sbjct: 1273 LTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHA 1332
Query: 1363 VRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRR 1421
+++ + LREQ EEE A+ R L A +++++WR + E +A E EEA+++
Sbjct: 1333 LQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1392
Query: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
A+ + + + LE+ + RLQ E++D +D+E+ + L+KKQR FD++
Sbjct: 1393 LAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452
Query: 1482 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
LAE K + E E ++ E R L A EE E E +R+N+ L+ E+ L
Sbjct: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
GK++HELE+ + E +L++ + E E L E LR ++ +K +
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
Query: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
ER L +DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++ A
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1721
+ EA KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ +
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 1722 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1781
++R+R+ A+Q+ E ++ V + +++ +K++++ L QL+ E+EE
Sbjct: 1693 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Query: 1782 DRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTI 1841
++ +K + + EL E+ SA E ++ +E+ I++L+ RL E + A K +
Sbjct: 1753 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQL 1812
Query: 1842 AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGN 1901
LE+++ + E +LE E + S K +R++E+R+KE+ Q EE+R+ +L+D ++K
Sbjct: 1813 QKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQ 1872
Query: 1902 LRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
L+VK KRQ EEAEE+A+ + R++Q EL++ E A+ +V LR + R
Sbjct: 1873 LKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925
Score = 226 bits (576), Expect = 2e-58
Identities = 209/959 (21%), Positives = 432/959 (45%), Gaps = 57/959 (5%)
Query: 1052 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS---ELQEQMVEQQQRAEELRA 1108
KL K + + E R ++ ++E +LK L+ + EL+E+MV Q +L+
Sbjct: 831 KLYFKIKPLLKSAE-REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQL 889
Query: 1109 QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1168
Q+ +++ L A R + QL+K+ + +A + E E LE E + ++R
Sbjct: 890 QVQAEQDNLADAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942
Query: 1169 LGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1225
L +E L+ +++D TL ++ + + +TE L+E + L++
Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002
Query: 1226 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQ 1285
H QAL +L + ++ K ++ LE +V +L L + R + E+ +R+LE
Sbjct: 1003 HQQALDDLQAEEDKVN----TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1058
Query: 1286 LQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDA 1345
L+ Q D E + + E+L++ EL ++ + + ++ +L K+L +A++ +
Sbjct: 1059 LKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEEL 1118
Query: 1346 QELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1405
+E L+ E A+ + + E + E+LEE A + +A+ + RR
Sbjct: 1119 EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178
Query: 1406 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDAT 1458
EE EA A R+ ++ +AE E +D L+R +++L++E LDD T
Sbjct: 1179 EEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232
Query: 1459 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LT 1514
++EQ + + LEK R + + E ++ EE +R+ + + A+ + L+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSVNDLTSQRAKLQTENGELS 1288
Query: 1515 RALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT 1574
R L+E++ +L R +LE L ++ K+ + L A + A + LR Q
Sbjct: 1289 RQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYE 1348
Query: 1575 ELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEER 1634
E + + + V +T++E D R E EE +++LA++L++AE +
Sbjct: 1349 EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVN 1408
Query: 1635 KQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE 1694
+ + + +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 1695 EIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNL 1747
S+K + L E+ +L+ E L R + Q++ ++ +++ +
Sbjct: 1469 S-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521
Query: 1748 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1807
+ + + ++QLE +L+ LEE +++ E + + L+ + E+ ER + K
Sbjct: 1522 TIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEK 1579
Query: 1808 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILS 1865
E Q ++ + DA R+R++ +E L + E QL R +
Sbjct: 1580 DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEA 1639
Query: 1866 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1925
K V+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R
Sbjct: 1640 QKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR 1699
Query: 1926 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
+ ++EL + +E + ++ + T+L N+ ++ + ++E ++E+A++A
Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%)
Query: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 941
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
Query: 942 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 985
+EL VV + E ++ E+E E S ++Q +KK++ + +L+ +E
Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744
Query: 986 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1045
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802
Query: 1046 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1104
+K K K EA + ++E+ L E+K E K R+ + EL Q E ++
Sbjct: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862
Query: 1105 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1164
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922
Query: 1165 QRRDLG 1170
+ RD+G
Sbjct: 1923 KSRDIG 1928
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 1305 bits (3378), Expect = 0.0
Identities = 722/1911 (37%), Positives = 1151/1911 (60%), Gaps = 21/1911 (1%)
Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA
Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
+T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
Query: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 213 GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
YLLEKSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S +
Sbjct: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328
Query: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
+E T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 329 QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388
Query: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
L L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+
Sbjct: 389 YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448
Query: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 449 QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
Query: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 507 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
Query: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
FQ+P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A++
Sbjct: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
Query: 646 WKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIV 705
+ G E + G GG+ + F+TV L++E+L++LM L +T+P FVRCI+
Sbjct: 624 FS---GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680
Query: 706 PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG- 764
PN K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G
Sbjct: 681 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740
Query: 765 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 824
F+D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG
Sbjct: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
Query: 825 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 884
+LAR +Q+ +++ A+ +Q N +++ ++HW W +LF K+KPLL+ ++ + +
Sbjct: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
Query: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944
E QK+++ +S + EL+ ++ L +E+ L Q++AEAE A+AEE +L K +
Sbjct: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
Query: 945 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004
LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K
Sbjct: 921 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
Query: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1064
+K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+
Sbjct: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
Query: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1124
E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +KE E+ ++
Sbjct: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100
Query: 1125 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1184
EDE QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+
Sbjct: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160
Query: 1185 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244
+T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K
Sbjct: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
Query: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1304
EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R +
Sbjct: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280
Query: 1305 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
+ R Q E S L+E E+ +LS+ + Q+ + + L+EE +AK AL ++
Sbjct: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAA 1423
+ + LREQ EEE ++ R L A ++++WR + E +A E EEA+++ A
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+ +A + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LA
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
E K E E ++ E R + A EE + E L+R+N+ L+ E+ L
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
+ GK +HELE+ + EQ +L+A + E E L E LR+++ + +K++ +R
Sbjct: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
+ +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A +
Sbjct: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
EA++ R Q +K+ +++ S+E++ Q E+R L+AE+ L+ L
Sbjct: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++
Sbjct: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
+K + + EL E+ SA E ++ +E+ +++L+ RL E + A K I
Sbjct: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+++ + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
VK KRQ EEAEE+++ A R+LQ ELE+ E A+ +V LR + R
Sbjct: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
Score = 224 bits (572), Expect = 5e-58
Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)
Query: 1075 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R +
Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
Query: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1188
QL+K+ + +A + E E E E + ++R L +E L+ +++D TL
Sbjct: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 1189 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1248
++ + + +TE L+E + L++ H Q L +L + ++
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
Query: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308
K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
Query: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1368
+ + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + +
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
Query: 1369 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1428
E + E+LEE A + +A+ + RR EE EA R+ ++
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
Query: 1429 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1486
+AE E +D L+R +++L++E + M+++ V T+ K + +++ E++
Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 1487 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
+ L++ EE ++ A+ + + +R L+E++ +L R +A ++E L
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Query: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
++ K+ + L A + + + LR Q E ++ + A + V +T++
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
Query: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
E D R E EE +++LA++L+ AE + + +++L+ E+E+L +
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
Query: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1718
K+ R + E ++ EET E S+K + L E+ +++
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
Query: 1719 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1774
++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE +
Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
Query: 1775 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1834
++ E + ++ L++ + +E+ +R + K E Q I+ + DA R
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
Query: 1835 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1892
+R+ +E L + E QL R + + R + LK+ + +++ R +
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
Query: 1893 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1952
L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
Query: 1953 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
++ + L+E ++E+A++A
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
Score = 191 bits (486), Expect = 5e-48
Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%)
Query: 864 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 914
TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058
Query: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
+L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1023
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178
Query: 1024 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1065
K R+ LE+ + + AA E E++ +L +++ K E I D+
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 1066 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1125
+ K + LEK+ R L+ + SEL+ + EQQ+ +L AQ GR + E + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
Query: 1126 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1185
++ +QL + + + E + LE E A+ + + + LR + E+ +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358
Query: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
S Q SK EV + + E + ++E +++ Q L E +E
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418
Query: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1305
+ EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477
Query: 1306 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
K R+ EL + A E+ + L +E + + ++ D E + E + L +
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1423
+E E L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
R E++ L + + + R +++++ +L++ + L ++ + + R +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1538
+ + + A+ +E + + E RA L +EE + E+ ER + EL
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717
Query: 1539 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1582
+L+++K D+ + E+E + A A + +T+ + +EL
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 1583 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1634
+D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + E+
Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Query: 1635 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1673
K+ AV +K E ++EL +A++ S + EEA +Q
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Query: 1674 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
A+ ++L E+EE + ++++ ++ R+K E + EE
Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 1305 bits (3378), Expect = 0.0
Identities = 722/1911 (37%), Positives = 1151/1911 (60%), Gaps = 21/1911 (1%)
Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA
Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92
Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
+T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P
Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152
Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212
Query: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 213 GKIQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 268
Query: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
YLLEKSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S +
Sbjct: 269 YLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDD 328
Query: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
+E T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 329 QEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAA 388
Query: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
L L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+
Sbjct: 389 YLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQ 448
Query: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 449 QLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 506
Query: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 507 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 563
Query: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
FQ+P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A++
Sbjct: 564 ANFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQL 623
Query: 646 WKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIV 705
+ G E + G GG+ + F+TV L++E+L++LM L +T+P FVRCI+
Sbjct: 624 FS---GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCII 680
Query: 706 PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG- 764
PN K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G
Sbjct: 681 PNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ 740
Query: 765 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 824
F+D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG
Sbjct: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
Query: 825 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 884
+LAR +Q+ +++ A+ +Q N +++ ++HW W +LF K+KPLL+ ++ + +
Sbjct: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
Query: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944
E QK+++ +S + EL+ ++ L +E+ L Q++AEAE A+AEE +L K +
Sbjct: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
Query: 945 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004
LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K
Sbjct: 921 LEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 980
Query: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1064
+K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+
Sbjct: 981 VKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL 1040
Query: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1124
E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +KE E+ ++
Sbjct: 1041 EGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKI 1100
Query: 1125 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1184
EDE QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+
Sbjct: 1101 EDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1160
Query: 1185 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244
+T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K
Sbjct: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
Query: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1304
EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R +
Sbjct: 1221 QKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLT 1280
Query: 1305 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
+ R Q E S L+E E+ +LS+ + Q+ + + L+EE +AK AL ++
Sbjct: 1281 AQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQ 1340
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAA 1423
+ + LREQ EEE ++ R L A ++++WR + E +A E EEA+++ A
Sbjct: 1341 SSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLA 1400
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+ +A + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LA
Sbjct: 1401 QRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILA 1460
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
E K E E ++ E R + A EE + E L+R+N+ L+ E+ L
Sbjct: 1461 EWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTE 1520
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
+ GK +HELE+ + EQ +L+A + E E L E LR+++ + +K++ +R
Sbjct: 1521 QIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDR 1580
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
+ +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A +
Sbjct: 1581 KIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1640
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
EA++ R Q +K+ +++ S+E++ Q E+R L+AE+ L+ L
Sbjct: 1641 MAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ 1700
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++
Sbjct: 1701 TERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEK 1760
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
+K + + EL E+ SA E ++ +E+ +++L+ RL E + A K I
Sbjct: 1761 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+++ + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
VK KRQ EEAEE+++ A R+LQ ELE+ E A+ +V LR + R
Sbjct: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931
Score = 224 bits (572), Expect = 5e-58
Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%)
Query: 1075 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R +
Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912
Query: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1188
QL+K+ + +A + E E E E + ++R L +E L+ +++D TL
Sbjct: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971
Query: 1189 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1248
++ + + +TE L+E + L++ H Q L +L + ++
Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027
Query: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308
K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+
Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087
Query: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1368
+ + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + +
Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147
Query: 1369 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1428
E + E+LEE A + +A+ + RR EE EA R+ ++
Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205
Query: 1429 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1486
+AE E +D L+R +++L++E + M+++ V T+ K + +++ E++
Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261
Query: 1487 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
+ L++ EE ++ A+ + + +R L+E++ +L R +A ++E L
Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321
Query: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
++ K+ + L A + + + LR Q E ++ + A + V +T++
Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381
Query: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
E D R E EE +++LA++L+ AE + + +++L+ E+E+L +
Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441
Query: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1718
K+ R + E ++ EET E S+K + L E+ +++
Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494
Query: 1719 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1774
++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE +
Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554
Query: 1775 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1834
++ E + ++ L++ + +E+ +R + K E Q I+ + DA R
Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612
Query: 1835 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1892
+R+ +E L + E QL R + + R + LK+ + +++ R +
Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672
Query: 1893 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1952
L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N
Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732
Query: 1953 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
++ + L+E ++E+A++A
Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764
Score = 191 bits (486), Expect = 5e-48
Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%)
Query: 864 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 914
TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058
Query: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
+L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ
Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1023
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178
Query: 1024 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1065
K R+ LE+ + + AA E E++ +L +++ K E I D+
Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 1066 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1125
+ K + LEK+ R L+ + SEL+ + EQQ+ +L AQ GR + E + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298
Query: 1126 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1185
++ +QL + + + E + LE E A+ + + + LR + E+ +
Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358
Query: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
S Q SK EV + + E + ++E +++ Q L E +E
Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418
Query: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1305
+ EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++
Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477
Query: 1306 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
K R+ EL + A E+ + L +E + + ++ D E + E + L +
Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1423
+E E L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
R E++ L + + + R +++++ +L++ + L ++ + + R +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1538
+ + + A+ +E + + E RA L +EE + E+ ER + EL
Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717
Query: 1539 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1582
+L+++K D+ + E+E + A A + +T+ + +EL
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 1583 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1634
+D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + E+
Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Query: 1635 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1673
K+ AV +K E ++EL +A++ S + EEA +Q
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Query: 1674 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
A+ ++L E+EE + ++++ ++ R+K E + EE
Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 1305 bits (3377), Expect = 0.0
Identities = 758/1922 (39%), Positives = 1130/1922 (58%), Gaps = 31/1922 (1%)
Query: 48 VEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKA 107
+ W ++ VWVP E + A ++ E + + L + ++Q MNPP+F
Sbjct: 69 IPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLL 128
Query: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
EDMA +T LNEASVLHNLR+RY +IYTYSGLFCV INPYK LP+YT ++V Y+GK+R
Sbjct: 129 EDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRR 188
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
+ PPH+YAV + AY ML++R++QS+L TGESGAGKT NTK+VIQY A VA+ G
Sbjct: 189 SDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG--- 245
Query: 228 PGVPAS-VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 286
PG A ++T + G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F +G +
Sbjct: 246 PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLAS 305
Query: 287 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSS 345
A+I++YLLEKSR I Q E S+H++YQ+L G +L+ LLL + Y F + G +
Sbjct: 306 ADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITV 365
Query: 346 PGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTA 404
+ E T ++ +LGFS +E + ++V A+L FGN+ K+++ +QA +
Sbjct: 366 DNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTES 425
Query: 405 AQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
A K L+G+ D + LL PR++VG +YV K Q+ EQ FA+ ALAKATY+RLFRWLV
Sbjct: 426 ADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLV 485
Query: 465 LRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
R+N+ LD + PRQ F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FN MFVLEQ
Sbjct: 486 SRINQTLDTKLPRQ--FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQ 543
Query: 524 EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE 583
EEY+REGI W F+DFGLDLQPCIDLIE+P G+L++L+EEC FPKA+D SF K+
Sbjct: 544 EEYKREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDN 600
Query: 584 QGGH-PKFQRPR---HLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639
G P FQ+PR + QA F V+HYAG V Y WL KN DPLN+ V + +S +
Sbjct: 601 HAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQN 660
Query: 640 RLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPS 699
RL A ++++ G E S G R + F+TV QL+KE+L++LM L T P
Sbjct: 661 RLLATLYENYAGSCSTEPPKS---GVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPH 717
Query: 700 FVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPN 759
FVRCIVPN K G ++ LVL QLRCNGVLEGIRICRQGFPNR+L+ +FRQRY IL P+
Sbjct: 718 FVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPS 777
Query: 760 AIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSF 818
AIP FMD ++A EK++ +L+LD Y+ G +K+FF+AG+L LEE RD ++ ++
Sbjct: 778 AIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLL 837
Query: 819 QAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEV 878
QA +RG L R +Q+ + AL +Q N A+ +++W W +LF K+KPLL+ + +E
Sbjct: 838 QARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEE 897
Query: 879 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL 938
L A EL+ ++ + + EL+ + +E+ LA QL+AE + A+AEE L
Sbjct: 898 LAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLL 957
Query: 939 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEK 998
K +LE V EL R+ +EEE + + +++L+ EL+ ++ + K + EK
Sbjct: 958 IKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEK 1017
Query: 999 VTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYE 1058
TE K+K E++ L++ ++L+KE+K L++ + EE++V +L K +L+ E
Sbjct: 1018 QATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLE 1077
Query: 1059 ATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1118
+ D+E L +E+K R + E+ KR+L+G+ QE + + Q ++L +L +K+ EL
Sbjct: 1078 QQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELS 1137
Query: 1119 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1178
R EDE AQ+ K ++E QA E +E+LE+ER AR + EKQR + ELE L
Sbjct: 1138 QLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSE 1197
Query: 1179 ELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE 1238
LE+ ++ Q+E KRE E+ L++ LEE HEA V LR++ + EL EQ++
Sbjct: 1198 RLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVD 1257
Query: 1239 QARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGER 1298
+R + EK + L EV +L A + +L A+ E+ R E QL E + + + +R
Sbjct: 1258 SLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQR 1317
Query: 1299 ARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLA 1358
A+A+ + R Q E +S L E E +LS+ + L + + L+EE++AK A
Sbjct: 1318 QLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSA 1377
Query: 1359 LGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEE 1417
L V+A+ + LREQ EEEA A+ R L A A++++WR + E +A E EE
Sbjct: 1378 LAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEE 1437
Query: 1418 ARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRK 1477
A+++ A + + + LE+ + RLQ E +D T++LE+ + L+KKQR
Sbjct: 1438 AKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRH 1497
Query: 1478 FDQLLAEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEEEQEAREELERQNR 1532
++ L E R EE + E E +RE+R L L EE EA E L+R+N+
Sbjct: 1498 LERALEER-----RRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENK 1552
Query: 1533 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1592
L+ E+ L GKS+ ELE+ + E ++++A + E E L E LR+++
Sbjct: 1553 NLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQL 1612
Query: 1593 TVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELE 1652
+ +K + +R L +DE RR + + + D E + R A+ +KK+EG+L
Sbjct: 1613 ELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLN 1672
Query: 1653 ELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEA 1712
+L+ Q+ A + EA R MQAQ+KE +E + E+ Q + E+R L A
Sbjct: 1673 DLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAA 1732
Query: 1713 EVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEE 1772
E+ L+ L +R+RR A+Q+ E + + + +L +K++LE L QL E+EE
Sbjct: 1733 ELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEE 1792
Query: 1773 EQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAG 1832
++ +K + + EL E+ SA E ++ LE+ ++EL+ RL E +
Sbjct: 1793 AAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQA 1852
Query: 1833 ARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1892
A K + LE+K+ + E +L+ E ++ + K VR+ E+R+KE+ Q EE+R+ +
Sbjct: 1853 ALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLAR 1912
Query: 1893 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1952
++D ++K +VK KRQ EEAE++A+ A R+ Q EL+D E A+ + LR R
Sbjct: 1913 MQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRAR 1972
Query: 1953 LR 1954
R
Sbjct: 1973 TR 1974
Score = 249 bits (637), Expect = 1e-65
Identities = 234/935 (25%), Positives = 414/935 (44%), Gaps = 60/935 (6%)
Query: 1075 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
R EL L+ L + + EL+E V Q +L QL +++ L A R
Sbjct: 902 RAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH------ 955
Query: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1188
L+KS + + + E E LE E +RR L +E L+ +++D TL
Sbjct: 956 -LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAE 1014
Query: 1189 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1248
+++ + + +TE L+E + L++ H QALG+L Q E+ R A
Sbjct: 1015 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL--QAEEDR--VSALT 1070
Query: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308
K +L LE +V +L L + R + E+ +R+LE L+ Q D + + + EKL+
Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130
Query: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1368
+ +EL +S + + + ++ K++ +A+ + L+EE A+ A +RV A
Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE----LEEELEAERAARARVEKQRA 1186
Query: 1369 EAAG----LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1424
EAA L E+LEE A + +A+L RR EE A EA A RR
Sbjct: 1187 EAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQA 1246
Query: 1425 EAEALTQRLAEKTETVDR----LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1480
E A L E+ +++ R LE+ + L+ E+DD ++E + ++ EK R ++
Sbjct: 1247 EGAA---ELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303
Query: 1481 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1540
L+E K V + A + + + L+R LEE++ +L R LE
Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363
Query: 1541 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1600
L ++ K+ L A + + LR Q E + + + V +++
Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423
Query: 1601 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1660
+E D R E EE +++LA +L++AE + + + A+ +L+ E E++ ++
Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLEL-- 1481
Query: 1661 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-- 1718
E A + + + L R +EE R EE+ + +++ +GL E+ RL+
Sbjct: 1482 -----ERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536
Query: 1719 -----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEE 1773
E L R + Q++ ++ D+V+ S + + K+ LEG +++ LEE
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596
Query: 1774 QSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEED 1830
+ EL + + L +Q+E + +R + K E R+ +R ++ L+ L D
Sbjct: 1597 EGALEL--EETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL---D 1651
Query: 1831 AGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERR 1888
A RAR++ +E L E QL TR+ + R + +LKE +EE+R
Sbjct: 1652 AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQR 1711
Query: 1889 VADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTT 1948
+A +L +Q + R L +LEE + + RR ++EL + TE ++ + T
Sbjct: 1712 LAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTG 1771
Query: 1949 LRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983
L N+ ++ + +EE EAEE
Sbjct: 1772 LLNQKKK----LEADLAQLSGEVEEAAQERREAEE 1802
Score = 199 bits (507), Expect = 2e-50
Identities = 241/979 (24%), Positives = 408/979 (41%), Gaps = 183/979 (18%)
Query: 864 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-----LEEERAR 916
TK K LQ Q + LQA + + + + + ++V +L+ + Q ++ ERA+
Sbjct: 1042 TKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAK 1101
Query: 917 --LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
L L+ E A+A + + +L + ++ + +S+L RV +E+ QMQ + K LQ
Sbjct: 1102 RKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1161
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1034
+ELE LEAE AR +++ ++ ++++ E L E+ + +R+ R A
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERL---EEAGGASAGQREGCRKREA 1218
Query: 1035 EFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL-------EKLKRRLDG 1087
E E EE L++EAT+A + RK+ +G EL ++++++L+
Sbjct: 1219 ELGRLRRELEEAA-------LRHEATVAALR---RKQAEGAAELGEQVDSLQRVRQKLEK 1268
Query: 1088 ESSELQEQM------VEQQQRAEELRAQLGR-----------KEEELQAALA-------R 1123
E SEL+ ++ VE RA+ +L R K EELQ LA R
Sbjct: 1269 EKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGR 1328
Query: 1124 AEDEGGARAQLLK---------SLREAQAA--LAEAQEDLESERVARTKAEKQRRDLGEE 1172
+ E G ++LL+ S +A AA L E + LE E A++ + L +
Sbjct: 1329 LQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD 1388
Query: 1173 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1232
+ LR + E+ ++ Q L SK EV + + E + ++E +++ L E
Sbjct: 1389 CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQE 1448
Query: 1233 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELS------------------SLQTARQE 1274
E +E A + EK +L L+ E ++ EL +L+ R++
Sbjct: 1449 AEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ 1508
Query: 1275 GEQRRRRLELQLQEVQG------RAGDGERARAEAAEKLQRA------------------ 1310
E+ +R LE +E +G R G EA E L+R
Sbjct: 1509 EEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLS 1568
Query: 1311 ---------------------QAELENVSGALNEAESKTIRLSKELSSTEAQL------- 1342
QA LE GAL E+KT+R+ ELS +A++
Sbjct: 1569 GKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEK 1628
Query: 1343 ---------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERA 1387
Q L ETRA+ + ME + L QL A
Sbjct: 1629 DEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688
Query: 1388 GRELQTAQAQLSEWRR-RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERG 1446
+ QAQL E + R EE+ A E E+A+ R A L L E +++ ER
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQA-LERRASLLAAELEELRAALEQGERS 1747
Query: 1447 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1506
RR +QEL +AT L + L +++K + LA+ V A +ER AE + ++
Sbjct: 1748 RRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKA 1807
Query: 1507 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 1566
A + L++EQ+ LER + L ++V EL+ AEQAA
Sbjct: 1808 ITDAAMMAEELKKEQDTSAHLERMKKTLE--------------QTVRELQARLEEAEQAA 1853
Query: 1567 -NDLRAQVTELEDELTAAEDAKLR-LEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLR 1624
+ QV +LE AK+R LE + A + +H L+G R+ ++++
Sbjct: 1854 LRGGKKQVQKLE--------AKVRELEAELDAEQKKHAEALKGV--------RKHERRVK 1897
Query: 1625 DAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR 1684
+ + +E+RK KL+ +++ K Q A Q + + RK Q ++ +
Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957
Query: 1685 EVEETRTSREEIFSQNRES 1703
+ T ++ ++ R++
Sbjct: 1958 RADMAETQANKLRARTRDA 1976
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 1301 bits (3366), Expect = 0.0
Identities = 719/1913 (37%), Positives = 1155/1913 (60%), Gaps = 27/1913 (1%)
Query: 52 ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109
A+ V+V F A + R+ G+ A+ E +G + + DQ+ MNPPK+ K ED
Sbjct: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90
Query: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169
MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E
Sbjct: 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150
Query: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229
PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE
Sbjct: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210
Query: 230 VPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 289
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+I
Sbjct: 211 TSGKMQ----GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
Query: 290 ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG- 347
ETYLLEKSR Q K E S+HIFYQ++ L LL+ + Y F++ G + P
Sbjct: 267 ETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSI 326
Query: 348 QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQK 407
++E T ++ +LGF+ +E +S+ ++ AV+ +GN+ K+++ +QA A K
Sbjct: 327 DDQEELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADK 386
Query: 408 LCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRL 467
L L D +AL PR+KVG +YV K QT +Q A+ ALAKA Y+++F W+V R+
Sbjct: 387 AAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRI 446
Query: 468 NRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 526
N+ LD + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY
Sbjct: 447 NQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
Query: 527 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-G 585
++EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G
Sbjct: 505 KKEGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLG 561
Query: 586 GHPKFQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
FQ+P+ + +A FS++HYAG VDY WL KN DPLN+ V L +S + A
Sbjct: 562 KSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLA 621
Query: 644 EIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
++ G G E + G G GG+ + F+TV L++E+L++LM L +T+P FVRC
Sbjct: 622 LLFV---GATGAE--AEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRC 676
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
I+PN K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+
Sbjct: 677 IIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPE 736
Query: 764 G-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 822
G F+D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA
Sbjct: 737 GQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMC 796
Query: 823 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 882
RG+LAR +QK +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ +
Sbjct: 797 RGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANM 856
Query: 883 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 942
+E +K +E ++ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K
Sbjct: 857 KEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTK 916
Query: 943 QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1002
+LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE
Sbjct: 917 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 976
Query: 1003 AKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIA 1062
K+K E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E +
Sbjct: 977 NKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVD 1036
Query: 1063 DMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
D+E L +E+K R +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ +
Sbjct: 1037 DLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQS 1096
Query: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182
+ EDE QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+
Sbjct: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEE 1156
Query: 1183 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242
+T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R
Sbjct: 1157 AGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQR 1216
Query: 1243 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1302
K EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R +
Sbjct: 1217 VKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276
Query: 1303 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
+ R Q E S L+E ++ +LS+ + Q+ + + L+EE +AK AL
Sbjct: 1277 LTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHA 1336
Query: 1363 VRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRR 1421
+++ + LREQ EEE A+ R + A +++++WR + E +A E EEA+++
Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKK 1396
Query: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
A+ + + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++
Sbjct: 1397 LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKI 1456
Query: 1482 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
LAE K E E ++ E R + A EE + E L+R+N+ L+ E+ L
Sbjct: 1457 LAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1516
Query: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
+ GK +HELE+ + EQ ++L+A + E E L E LR+++ + +K++
Sbjct: 1517 TEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV 1576
Query: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
+R + +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A
Sbjct: 1577 DRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHA 1636
Query: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1721
+ EA++ R QA +K+ +++ S+E++ Q E+R L+AE+ L+ L
Sbjct: 1637 NRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATL 1696
Query: 1722 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1781
++R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ +
Sbjct: 1697 EQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAE 1756
Query: 1782 DRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTI 1841
++ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A K I
Sbjct: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQI 1816
Query: 1842 AALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGN 1901
LE+++ + E ++E E + + + K +R+ E+++KE+ Q EE+R+ +L+D ++K
Sbjct: 1817 QKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQ 1876
Query: 1902 LRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
+VK KRQ EEAEE+++ + RR+Q ELE+ E A+ +V LR + R
Sbjct: 1877 AKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929
Score = 227 bits (579), Expect = 8e-59
Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%)
Query: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
Query: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 891 LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
Query: 1166 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1222
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 1223 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1282
++ H Q L +L + ++ K ++ LE +V +L L + R + E+ +R+L
Sbjct: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059
Query: 1283 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1342
E L+ Q D E + + EKL++ + E+ + + + ++ ++L K++ +A++
Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 1343 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1402
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 1403 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1461
R EE EA R++ A L +++ +LE+ + ++ E+DD ++
Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239
Query: 1462 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1517
E + LEK R + L+E K EE++R + + AR + +R L
Sbjct: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295
Query: 1518 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1577
+E+ +L R +A ++E L ++ K+ L A + + + LR Q E +
Sbjct: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355
Query: 1578 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1637
+ + A + V +T++E D R E EE +++LA++L+DAE + +
Sbjct: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415
Query: 1638 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1697
+++L+ E+E+L + K+ R + E ++ EET E
Sbjct: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475
Query: 1698 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1757
++R L ++ ++L R + QQ+ ++ +++A G + + K+
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
Query: 1758 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1817
Q+E +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593
Query: 1818 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1875
I+ + DA R+R+ +E L + E QL R + + R +
Sbjct: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653
Query: 1876 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1935
LK+ L +++ R + L++QL R L+ ++EE + + R+ ++EL D
Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713
Query: 1936 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
+E + ++ + T+L N ++ + ++E ++E+A++A
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762
Score = 189 bits (480), Expect = 2e-47
Identities = 199/947 (21%), Positives = 418/947 (44%), Gaps = 94/947 (9%)
Query: 864 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 914
TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 997 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056
Query: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
+L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ
Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1023
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176
Query: 1024 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1065
K R+ LE+ + + AA E E++ +L +++ K E I D+
Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236
Query: 1066 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1125
+ K + LEK+ R L+ + SE++ + EQQ+ +L AQ R + E + +
Sbjct: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296
Query: 1126 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1185
++ +QL + + + E + LE E A++ + + + LR + E+ +
Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356
Query: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
+ Q SK EV + + E + ++E +++ Q L + E +E
Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCA 1416
Query: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1305
+ EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1475
Query: 1306 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
K R+ EL + A E+ + L +E + + ++ D E + E + L +
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1423
+E E + L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHI 1595
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
R E++ L + + + R +++++ +L++ + L ++ + + R +L
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILK 1655
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1538
+ + + A+ +E + + E RA L +EE + E+ ER + EL
Sbjct: 1656 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1715
Query: 1539 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1582
+L+++K D+ + E+E + A A + +T+ + +EL
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775
Query: 1583 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1634
+D LE + L+ Q +DLQ R DEA G+++ ++L ++R+ E E + E+
Sbjct: 1776 EQDTSAHLERMKKNLE-QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834
Query: 1635 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1673
K+ AV +K E +++EL +A++ S + EEA +Q
Sbjct: 1835 KRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894
Query: 1674 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
++ + + E+EE + ++++ ++ R+K E + EE
Sbjct: 1895 VNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 1298 bits (3359), Expect = 0.0
Identities = 728/1914 (38%), Positives = 1145/1914 (59%), Gaps = 32/1914 (1%)
Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111
A+ +V + ++ + + VE E R L + + + MNPPKF + EDMA
Sbjct: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92
Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171
LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y +VE YRGKKR E P
Sbjct: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152
Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP 231
PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ K+
Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKK--- 209
Query: 232 ASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIET 291
+ G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IET
Sbjct: 210 ---DSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIET 266
Query: 292 YLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QE 349
YLLEKSR Q K E S+HIFYQ+L +L LL+ + Y F++ G +
Sbjct: 267 YLLEKSRVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDD 326
Query: 350 RELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLC 409
E T ++ +LGF+ EE + ++ AV+ +GN+ K+++ +QA A K
Sbjct: 327 AEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTA 386
Query: 410 RLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNR 469
L+GL +D +AL PR+KVG +YV K QT +Q A+ AL+K+ YE+LF W+V R+N+
Sbjct: 387 YLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQ 446
Query: 470 ALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 528
LD + PRQ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++
Sbjct: 447 QLDTKLPRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKK 504
Query: 529 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGH 587
EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G
Sbjct: 505 EGIEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKS 561
Query: 588 PKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEI 645
FQ+P+ ++ +A+ FS++HYAG VDY + WL KN DPLN+ V L +S++RL A +
Sbjct: 562 NNFQKPKVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHL 621
Query: 646 WKD---VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 702
+ + G ++V+ + + F+TV L++E+L++LM+ L T+P FVR
Sbjct: 622 YATFATADADSGKKKVA---------KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVR 672
Query: 703 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 762
CI+PN K G +E LVL QLRCNGVLEGIRICR+GFPNRIL+ +F+QRY +L +AIP
Sbjct: 673 CIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIP 732
Query: 763 KG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAA 821
+G F+D K+ACEK++ ++++D Y+ G +K+FF+AG+L LEE RD ++ +I QA
Sbjct: 733 EGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAV 792
Query: 822 ARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQA 881
RG+L R FQK Q++ ++ +Q N +++ ++HW W +LF K+KPLL+ ++ +
Sbjct: 793 CRGFLMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMAT 852
Query: 882 RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAAR 941
+E QK ++ +S + EL+ ++ L +E+ L Q++AE+E +AEE +L
Sbjct: 853 MKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKA 912
Query: 942 KQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTT 1001
K +LE + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK T
Sbjct: 913 KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHAT 972
Query: 1002 EAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI 1061
E K+K E+L L++ +KL++E+K L++ + EE+KV SLNK + K E +
Sbjct: 973 ENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQV 1032
Query: 1062 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1121
D+E L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ E
Sbjct: 1033 EDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQ 1092
Query: 1122 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1181
++ EDE Q K ++E QA + E +E++E+ER R K EKQR D ELE L LE
Sbjct: 1093 SKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLE 1152
Query: 1182 DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQAR 1241
+ T+ Q EL KRE E +L++ LEE T HEA V LR++H ++ EL EQ++ +
Sbjct: 1153 EAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQ 1212
Query: 1242 RGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 1301
R K EK + + E+ +L + + S+ ++ E+ R LE QL E +G+ + +R+ +
Sbjct: 1213 RVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLS 1272
Query: 1302 EAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1361
E + R Q E +S L E ES +LS+ + Q + + L+EE +AK AL
Sbjct: 1273 ELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAH 1332
Query: 1362 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARR 1420
+++ + LREQ EEE + R L A +++++WR + E +A E EEA++
Sbjct: 1333 ALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK 1392
Query: 1421 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1480
+ A+ + +++ LE+ ++RLQ E++D +D+E+ L + L+KKQR FD+
Sbjct: 1393 KLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDK 1452
Query: 1481 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1540
+LAE K + E E + E R L A EE + E ++R+N+ L E+
Sbjct: 1453 VLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIAD 1512
Query: 1541 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1600
L + GK++HELE++ + E D++ + E E L E LR+++ + +K++
Sbjct: 1513 LTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSE 1572
Query: 1601 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1660
+R + +DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++
Sbjct: 1573 IDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSH 1632
Query: 1661 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
A + E +K LR +Q Q+K+ +++ +E++ Q E+R L+AEV L+
Sbjct: 1633 ANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRAT 1692
Query: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1780
L ++RAR+ A+Q+ + + V + +++ K++LE L QL+ E+E+ ++
Sbjct: 1693 LEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNA 1752
Query: 1781 NDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMT 1840
++ +K + + EL E+ SA E ++ LE+ +++L+ RL E + A K
Sbjct: 1753 EEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQ 1812
Query: 1841 IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKG 1900
I LE+++ + E +LE E ++ S K +R+ E+R+KE+ Q EE+R+ +L+D ++K
Sbjct: 1813 IQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKL 1872
Query: 1901 NLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
++VK KRQ EEA+E+A+ R+ Q ELE+ E A+ +V LR + R
Sbjct: 1873 QVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926
Score = 145 bits (365), Expect = 5e-34
Identities = 188/868 (21%), Positives = 357/868 (41%), Gaps = 172/868 (19%)
Query: 852 LKLRHWQWWRLFTKVKPL----LQVTRQDEVLQARAQELQ-----------KVQELQQQS 896
LK + +++ +L +KV+ LQ ++ + LQAR +EL+ K ++ +
Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140
Query: 897 AREVGELQGRV--------AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 948
ARE+ EL R+ Q+E + R AE L+ +L + +AA +++
Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200
Query: 949 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEA 1003
V+EL ++ + ++++ EK + I +L + +E+ ++ L+ LE +EA
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
+ K E ++ S+L+ ++ L+ E S Q E+E V L++ + + +
Sbjct: 1261 RGKNEE-----IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
++ +L +E K + L + + L+EQ E+Q+ EL+ L + E+ +
Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375
Query: 1124 AEDEGGARAQLLKSLREAQAA-LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182
E + R + L+ ++ A L +++E +E+ EK ++ L E+E L ++E
Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435
Query: 1183 T------LDSTNAQ-----QELRSKREQEVTELKKTLEEETRI----------HEAAVQE 1221
LD E ++K E+ EL+ +L+E + +E A+ +
Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495
Query: 1222 LR------QRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1275
L + Q + +L EQ+ + + EK+R +E E ++++ L + A +
Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
Query: 1276 EQRRRRLELQLQEVQGR----------------------------AGDGE-RARAEAAEK 1306
E + R++L+L +V+ A D E R+R EA
Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
Query: 1307 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL------QEETRAKLALG 1360
++ + +L + L+ A + K L S + QL D Q L QE+ + +LA+
Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675
Query: 1361 SR-VRAMEAEAAGLREQLEEEAAARERAGREL----------QTAQAQLSEWRRRQEEEA 1409
R ++AE LR LE+ AR+ A +EL T L +++ E +
Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735
Query: 1410 GALEA-----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1458
L++ EE ++A +A + + L ++ +T LER ++ L+Q + D
Sbjct: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795
Query: 1459 MDLEQQRQLVSTLEKKQ-----------------------------RKFDQLLAE----- 1484
L++ QL KKQ RK+++ + E
Sbjct: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855
Query: 1485 --EKAAVLRAVE--------------ERERAEAEGREREARALSLTRALEEEQEAREELE 1528
++ VLR + + E A+ + + LEE +E + E
Sbjct: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915
Query: 1529 RQNRALRAELEALLSSKDDVGKSVHELE 1556
Q LRA+ SS+ VHE E
Sbjct: 1916 SQVNKLRAKTRDFTSSR----MVVHESE 1939
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 1298 bits (3358), Expect = 0.0
Identities = 722/1879 (38%), Positives = 1125/1879 (59%), Gaps = 25/1879 (1%)
Query: 84 ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143
E G L + DQ+ MNPPK+ K EDMA +T L+E VL+NL+ERY + +IYTYSGLFCV
Sbjct: 67 EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126
Query: 144 VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203
+NPYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG
Sbjct: 127 TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186
Query: 204 KTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVK 263
KT NTK+VIQY A +A + + +K+ S G LE Q++ ANP+LEAFGNAKTV+
Sbjct: 187 KTVNTKRVIQYFATIAVTGEKKKDE------SGKMQGTLEDQIISANPLLEAFGNAKTVR 240
Query: 264 NDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQL 323
NDNSSRFGKFIRI+F G + A+IETYLLEKSR Q K E S+HIFYQ+ L
Sbjct: 241 NDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDL 300
Query: 324 KADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVL 381
LL+ + Y F++ G + P ++E T ++ +LGF+ EE +S+ ++ AV+
Sbjct: 301 IEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVM 360
Query: 382 QFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTK 441
+GN+ K+++ +QA A K L L D +AL PR+KVG +YV K QT
Sbjct: 361 HYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTV 420
Query: 442 EQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQ 500
+Q A+ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS EQ
Sbjct: 421 QQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQ 478
Query: 501 LCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLA 560
LCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL CI+LIE+P G+ +
Sbjct: 479 LCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFS 535
Query: 561 LLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANE 617
+L+EEC FPKATD SF K+ Q G FQ+P+ ++ +A+ FS++HYAG VDY
Sbjct: 536 ILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITG 595
Query: 618 WLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRT 677
WL KN DPLND V L +S + A ++ E SS G + + F+T
Sbjct: 596 WLDKNKDPLNDTVVGLYQKSAMKTLASLFSTY---ASAEADSS---AKKGAKKKGSSFQT 649
Query: 678 VGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICR 737
V L++E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEGIRICR
Sbjct: 650 VSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICR 709
Query: 738 QGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFR 796
+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G +K+FF+
Sbjct: 710 KGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFK 769
Query: 797 AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH 856
AG+L LEE RD K+ II QA RG+L R +QK Q++ AL +Q N A++ ++H
Sbjct: 770 AGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKH 829
Query: 857 WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 916
W W +LF K+KPLL+ ++ + +E QK ++ +S + EL+ ++ L +E+
Sbjct: 830 WPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKND 889
Query: 917 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 976
L Q+++EA+ A+AEE +L K +LE + E+ R EEEE + ++ +K++L+
Sbjct: 890 LQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE 949
Query: 977 IQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1036
EL+ ++ E K++ EK TE K+K E++ L++ +KLSKE+K L++ +
Sbjct: 950 CSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQT 1009
Query: 1037 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1096
EE+KV L K + K E + D+E L +E+K R +LE+ KR+L+G+ QE
Sbjct: 1010 LDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQEST 1069
Query: 1097 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESER 1156
++ + ++L +L +KE E+ +++ EDE QL K ++E QA + E E++E+ER
Sbjct: 1070 MDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 1129
Query: 1157 VARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHE 1216
+R KAEKQR DL ELE + LE+ +T+AQ EL KRE E +L++ LEE T HE
Sbjct: 1130 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
Query: 1217 AAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1276
A V LR++H ++ EL EQ++ +R K EK + L+ E +L + ++ A+ E
Sbjct: 1190 AMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLE 1249
Query: 1277 QRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELS 1336
+ R LE Q+ E++ + + +R + + R Q E S L+E ++ +LS+
Sbjct: 1250 KMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQ 1309
Query: 1337 STEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQA 1396
++ Q+ + + L+EET+AK AL +++ + LREQ EEE + R L A +
Sbjct: 1310 ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANS 1369
Query: 1397 QLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD 1455
++++WR + E +A E EEA+++ A+ + + + LE+ ++RLQ E++
Sbjct: 1370 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVE 1429
Query: 1456 DATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTR 1515
D +D+E+ + L+KKQR FD++L+E K E E ++ E R +
Sbjct: 1430 DLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKN 1489
Query: 1516 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575
EE + E L R+N+ L+ E+ L + GK +HELE+ + EQ +++A + E
Sbjct: 1490 VYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEE 1549
Query: 1576 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1635
E L E LR+++ + +K++ +R + +DE ++ +R + + + D E +
Sbjct: 1550 AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIR 1609
Query: 1636 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1695
R A+ +KK+EG+L E++ Q+ A + E+++ R Q +KE +++ +E+
Sbjct: 1610 SRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQED 1669
Query: 1696 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1755
+ Q E+R L+AE+ L L ++R+R+ A+Q+ + ++ V + +++
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1729
Query: 1756 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1815
K++LE + QL+ E+EE S ++ +K + + EL E+ SA E ++ L
Sbjct: 1730 KKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL 1789
Query: 1816 ERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKR 1875
E+ +++L+ RL E + A K I LE+++ + E ++E E + + K +R+ E+R
Sbjct: 1790 EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERR 1849
Query: 1876 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1935
+KE+ Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ + R+LQ ELE+
Sbjct: 1850 VKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEA 1909
Query: 1936 TESAESMNREVTTLRNRLR 1954
E A+ +V LR + R
Sbjct: 1910 EERADIAESQVNKLRVKSR 1928
Score = 227 bits (579), Expect = 8e-59
Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%)
Query: 864 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 914
+K K LQ T Q + LQA ++ + + + + ++V +L+G + Q LE +
Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055
Query: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
+L L+ E + E + +L + ++ E +S L +++ +E+ Q+Q + K LQ
Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1034
I+EL +EAE +R K + ++ ++++ E L E+ S + +L + R A
Sbjct: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172
Query: 1035 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1072
EF + EE + LR K+ ++A++ + +L KE+
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Query: 1073 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
K + LEK+ R L+ + SEL+ + EQQ+ +L AQ R + E
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
Query: 1123 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1182
+ +++ +QL +S + + + E + LE E A+ + + + LR + E+
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 1183 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242
+ Q SK EV + + E + ++E +++ Q L E E +E
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
Query: 1243 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1302
+ EKT+ L+ EV +L ++ A ++++R + L E + + + + A E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471
Query: 1303 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1361
A++K R+ EL V E+ + L +E + + ++ D E + E + L
Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531
Query: 1362 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1421
+ +E E ++ LEE A+ E ++ Q +L++ + +
Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576
Query: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
+++AEK E +D+L+R R+ + + +T+D E + + + KK+ + D
Sbjct: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626
Query: 1482 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1535
E A L A R +G +E + L L AL +++ +E+L ER+ L+
Sbjct: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685
Query: 1536 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1595
AE+E L ++ + + ER+ ++AEQ D +V L + T+ + K +LE V
Sbjct: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738
Query: 1596 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1652
L+++ E +Q A E+ + K + DA + +E +K++ + +K LE ++
Sbjct: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794
Query: 1653 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1711
+L+ ++ A Q + KQ++K++A+++EL EVE + E R+ E+R+K L
Sbjct: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854
Query: 1712 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1764
+ VLRLQ+ L +A+ ++ + + E A+E +N NLSK
Sbjct: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900
Query: 1765 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1801
+L+ ELEE + +++ + KL ++ + T++SAE
Sbjct: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
Score = 219 bits (557), Expect = 3e-56
Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%)
Query: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
K+K L LK T +M + +K + EL K + + EL+E+MV + +
Sbjct: 838 KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889
Query: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165
L+ Q+ + + L A R E QL+K+ + +A + E E E E + +
Sbjct: 890 LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942
Query: 1166 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1222
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 943 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002
Query: 1223 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1282
++ H Q L +L + ++ K + LE +V +L L + R + E+ +R+L
Sbjct: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058
Query: 1283 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1342
E L+ Q D E + + EKL++ + E+ N+ + + ++ I+L K++ +A++
Sbjct: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118
Query: 1343 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1402
+ E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178
Query: 1403 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1459
R EE EA A R+ ++ +AE E +D L+R +++L++E + M
Sbjct: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232
Query: 1460 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1515
DL + +S + K + L ++ + + EE++R A+ + A +R
Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292
Query: 1516 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575
L+E+ +L R +A ++E L ++ K+ + L A + + + LR Q E
Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352
Query: 1576 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1635
++ + A + V +T++E D R E EE +++LA++L++AE +
Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412
Query: 1636 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1695
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472
Query: 1696 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1755
++R L ++ ++L R + QQ+ ++ +++A G + +
Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532
Query: 1756 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1815
K+Q+E +++ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590
Query: 1816 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1873
+ + DA R+R+ +E L + E QL R S + R +
Sbjct: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
Query: 1874 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1933
LKE L +++ R + L++QL R L+ ++EE + + R+ ++EL
Sbjct: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710
Query: 1934 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
D +E + ++ + T+L N ++ ++ V +V ++E ++E+A++A
Sbjct: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 1295 bits (3351), Expect = 0.0
Identities = 726/1911 (37%), Positives = 1147/1911 (60%), Gaps = 34/1911 (1%)
Query: 57 WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114
+VP + F A + R+ G+ AE E +G+ + + DQ+ + NPPKF K EDMA LT
Sbjct: 38 FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94
Query: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174
L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+
Sbjct: 95 FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154
Query: 175 YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVPAS 233
+++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+K+
Sbjct: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDN----- 209
Query: 234 VSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 293
+ + G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL
Sbjct: 210 -ANANKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYL 268
Query: 294 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 351
LEKSR I Q K E ++HIFYQ+L +L LL+ + Y F++ G S + E
Sbjct: 269 LEKSRVIFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSE 328
Query: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
T + VLGF+ EE + ++ A++ +GN+ K+++ +QA A K L
Sbjct: 329 ELMATDSAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYL 388
Query: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
+GL D + L PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V R+N L
Sbjct: 389 MGLNSADLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATL 448
Query: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
+ + PRQ F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EG
Sbjct: 449 ETKQPRQ--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 506
Query: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 589
I WTF+DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G
Sbjct: 507 IEWTFIDFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNN 563
Query: 590 FQRPRHLR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
FQ+PR+++ +A FS++HYAG VDY WL KN DPLN+ V AL +S+ +L A ++
Sbjct: 564 FQKPRNIKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFS 623
Query: 648 DVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIV 705
+ GD GG+ + F+TV L++E+L++LM L T+P FVRCI+
Sbjct: 624 SYA-------TADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCII 676
Query: 706 PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG- 764
PN K G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+G
Sbjct: 677 PNERKAPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQ 736
Query: 765 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 824
F+D ++ EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA ARG
Sbjct: 737 FIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARG 796
Query: 825 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 884
L R F+K +++ AL V+Q N A++ +++W W +L+ K+KPLL+ ++ + +
Sbjct: 797 QLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKE 856
Query: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 944
E +++E ++S EL+ ++ L +E+ L Q++AE + +AEE +L K +
Sbjct: 857 EFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQ 916
Query: 945 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 1004
LE V E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K
Sbjct: 917 LEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENK 976
Query: 1005 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1064
+K E++ L++ +KL+KE+K L++ + EE+KV SL+K ++K E + D+
Sbjct: 977 VKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDL 1036
Query: 1065 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1124
E L +E+K R +LE+ KR+L+G+ QE +++ + +L +L +KE ++ ++
Sbjct: 1037 EGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKI 1096
Query: 1125 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1184
EDE QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+
Sbjct: 1097 EDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG 1156
Query: 1185 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244
+T+ Q E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K
Sbjct: 1157 GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVK 1216
Query: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1304
EK + + E+ ++ + + + A+ E+ R LE Q E + + + +R+ +
Sbjct: 1217 QKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFT 1276
Query: 1305 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
+ + Q E ++ L E E+ +L++ S Q+ D + L+EE +AK AL ++
Sbjct: 1277 TQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQ 1336
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAA 1423
+ + LREQ EEE A+ R L A +++++WR + E +A E EEA+++ A
Sbjct: 1337 SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1396
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1483
+ + + + LE+ + RLQ E++D +D+E+ + L+KKQR FD++LA
Sbjct: 1397 QRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILA 1456
Query: 1484 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS 1543
E K + E E ++ E R L A EE E E +R+N+ L+ E+ L
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE 1516
Query: 1544 SKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHER 1603
+ GK+VHELE+ + E +L++ + E E L E LR ++ +K + ER
Sbjct: 1517 QLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIER 1576
Query: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663
L +DE E+ +R + + + D E + R + +KK+EG+L E++ Q++ A +
Sbjct: 1577 KLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANR 1636
Query: 1664 GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAA 1723
EA KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ +
Sbjct: 1637 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1696
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
++R+R+ A+Q+ E ++ V + +++ +K+++E L QL+ E+EE ++
Sbjct: 1697 TERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEK 1756
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
+K + + EL E+ SA E ++ +E+ I++L+ RL E + A K +
Sbjct: 1757 AKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQK 1816
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
LE+++ + E +LE E + S K +R++E+R+KE+ Q EE+++ +L+D ++K L+
Sbjct: 1817 LEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLK 1876
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
VK KRQ EEAEE+A+ + R++Q EL++ E A+ +V LR + R
Sbjct: 1877 VKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927
Score = 236 bits (601), Expect = 2e-61
Identities = 213/954 (22%), Positives = 431/954 (45%), Gaps = 57/954 (5%)
Query: 1052 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1111
K++ ++ + E KEE GR +++ + + EL+E+MV Q +L+ Q+
Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR--IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQ 894
Query: 1112 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1171
+++ L A R + QL+K+ + +A + E E LE E + ++R L +
Sbjct: 895 AEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED 947
Query: 1172 ELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1228
E L+ +++D TL ++ + + +TE L+E + L++ H Q
Sbjct: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 1229 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1288
AL +L Q+E+ + + K+++ LE +V +L L + R + E+ +R+LE L+
Sbjct: 1008 ALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
Query: 1289 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1348
Q D E + + EKL++ + ++ + + + + ++L K+L +A++ + +E
Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEE 1123
Query: 1349 LQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE 1408
L+ E A+ + + E + E+LEE A + +A+ + RR EE
Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183
Query: 1409 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATMDL 1461
EA A R+ ++ +AE E +D L+R +++L++E LDD T ++
Sbjct: 1184 TLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237
Query: 1462 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQ 1521
EQ + + LEK R + E + + A + + + L R LEE++
Sbjct: 1238 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1297
Query: 1522 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1581
+L R + ++E L ++ GK+ + L A + A + LR Q E +
Sbjct: 1298 ALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKA 1357
Query: 1582 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1641
+ + V +T++E D R E EE +++LA++L+DAE + + +
Sbjct: 1358 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLE 1417
Query: 1642 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1701
+ +L+ E+E+L + + K+ R + E ++ EE+++ E
Sbjct: 1418 KTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES------ 1471
Query: 1702 ESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1754
S+K + L E+ +L+ E L R + Q++ ++ +++ G + + +
Sbjct: 1472 -SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530
Query: 1755 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AESG 1811
++QLE +L+ LEE +++ E + + L+ + E+ ER + K E
Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEMEQA 1588
Query: 1812 RQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLV 1869
++ +R + L+ L DA R+R+++ +E L + E QL R + K V
Sbjct: 1589 KRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645
Query: 1870 RRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQ 1929
+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R+ +
Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705
Query: 1930 RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983
+EL + +E + ++ + T+L N+ ++ T + +EE V AEE
Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755
Score = 71.2 bits (173), Expect = 9e-12
Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%)
Query: 885 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 941
+L + ++ ++V LQ + L++ + +L + +RA +L A E L A
Sbjct: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686
Query: 942 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 985
+EL VV + E ++ E+E E S ++Q +KK+++ + +L++ +E
Sbjct: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746
Query: 986 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1045
+E + + +K T+A M E+L +D ++ L + +K +E + + + E E+
Sbjct: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804
Query: 1046 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1104
+K K K EA + ++E L E+K E K R+ + EL Q E ++
Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864
Query: 1105 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1164
L+ + + + +++A +AE+ L R+ Q L EA+E + K
Sbjct: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924
Query: 1165 QRRDLG 1170
+ RD+G
Sbjct: 1925 KSRDIG 1930
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 1285 bits (3325), Expect = 0.0
Identities = 709/1904 (37%), Positives = 1142/1904 (59%), Gaps = 25/1904 (1%)
Query: 59 PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118
P E + R+ G+ A+ E +G + + DQ+ MNPPK+ K EDMA +T L+E
Sbjct: 43 PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99
Query: 119 ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178
+VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+++++
Sbjct: 100 PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159
Query: 179 EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVS 238
+ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE PAS
Sbjct: 160 DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEE--PASGKM-- 215
Query: 239 YGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSR 298
G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR
Sbjct: 216 QGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 275
Query: 299 AIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQET 356
Q K E S+HIFYQ+L +L LL+ + + F++ G + P ++E T
Sbjct: 276 VTFQLKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMAT 335
Query: 357 LESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGV 416
++ +LGF+ +E +++ ++ AV+ +GN+ K+++ +QA A K L L
Sbjct: 336 DSAVDILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNS 395
Query: 417 TDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSP 475
D ++L PR+KVG ++V K QT +Q A+ ALAKA YE++F W+V R+N+ LD + P
Sbjct: 396 ADLLKSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQP 455
Query: 476 RQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTF 535
RQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F
Sbjct: 456 RQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEF 513
Query: 536 LDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPR 594
+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G FQ+P+
Sbjct: 514 IDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPK 570
Query: 595 HLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGI 652
+ +A FS++HYAG VDY WL KN DPLN+ V L +S + A ++ +
Sbjct: 571 PAKGKPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQ-- 628
Query: 653 VGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRA 712
+ G G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN K
Sbjct: 629 ---TAEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTP 685
Query: 713 GKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA 771
G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A
Sbjct: 686 GAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKA 745
Query: 772 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 831
EK++ ++E+D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+L R F
Sbjct: 746 SEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEF 805
Query: 832 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 891
+K +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ + +E +K +E
Sbjct: 806 RKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKE 865
Query: 892 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 951
++ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K +LE + E
Sbjct: 866 ELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKE 925
Query: 952 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1011
+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K E+
Sbjct: 926 VTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEE 985
Query: 1012 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1071
+ L++ +KL+KE+K L++ + EE+KV +L K + K E + D+E L +E
Sbjct: 986 MAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQE 1045
Query: 1072 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
+K +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ + EDE
Sbjct: 1046 KKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALA 1105
Query: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1191
QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+AQ
Sbjct: 1106 IQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQI 1165
Query: 1192 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K EK +
Sbjct: 1166 EMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEK 1225
Query: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311
L+ E+++L + + ++ A+ E+ R LE QL E++ + + +R E + + R
Sbjct: 1226 SELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLH 1285
Query: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
E S L+E ++ +LS+ + Q+ + + L+EET+AK L +++ +
Sbjct: 1286 TESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCD 1345
Query: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALT 1430
LREQ EEE A+ R + A +++++WR + E +A E EEA+++ A+ +
Sbjct: 1346 LLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1405
Query: 1431 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
+ + LE+ ++RLQ E++D +D+E+ L+KKQR FD++LAE K
Sbjct: 1406 EHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYE 1465
Query: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGK 1550
E E ++ E R + A EE + E L+R+N+ L+ E+ L + GK
Sbjct: 1466 ETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGK 1525
Query: 1551 SVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE 1610
+HELE+ + + ++L+ + E E L E LR+++ + +K++ +R + +DE
Sbjct: 1526 HIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDE 1585
Query: 1611 AGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVK 1670
++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + EA++
Sbjct: 1586 ELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR 1645
Query: 1671 QLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQ 1730
LR Q +K+ +++ ++++ Q E+R ++AEV L+ L ++R R+
Sbjct: 1646 NLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKM 1705
Query: 1731 AQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQ 1790
A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ +K +
Sbjct: 1706 AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITD 1765
Query: 1791 VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQ 1850
+ EL E+ SA E ++ +E+ +++L+ RL E + A K I LE+++ +
Sbjct: 1766 AAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRE 1825
Query: 1851 AEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQ 1910
E ++E E + + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ
Sbjct: 1826 LESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQ 1885
Query: 1911 LEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
EEAEE+++ A R+LQ ELE+ E A+ +V LR + R
Sbjct: 1886 AEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929
Score = 241 bits (615), Expect = 5e-63
Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%)
Query: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
K+K L LK T +M + + EK ++EL K + + EL+E+MV Q +
Sbjct: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890
Query: 1106 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165
L+ Q+ + + L A R + QL+K+ + +A + E E E E + +
Sbjct: 891 LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943
Query: 1166 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1222
+R L +E L+ +++D TL ++ + + +TE L+E + L
Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003
Query: 1223 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1282
++ H Q L +L Q+E+ + KT+L E +V +L L + + E+ +R+L
Sbjct: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059
Query: 1283 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1342
E L+ Q D E + + EKL++ + E+ N+ G + + ++ I+L K++ +A++
Sbjct: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119
Query: 1343 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1402
+ +E ++ E ++ + + E + E+LEE A + +A+ + R
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179
Query: 1403 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1462
R EE EA A R+ ++ +AE E +D L+R +++L++E + M++
Sbjct: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233
Query: 1463 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1515
+ T+ K + F+++ L ++ + + EE++R E ++AR + +R
Sbjct: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293
Query: 1516 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575
L+E+ +L R +A ++E L ++ K+ L A + A + LR Q E
Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353
Query: 1576 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1635
++ + + V +T++E D R E EE +++LA++L+DAE +
Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413
Query: 1636 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1695
+ +++L+ E+E+L + + K+ R + E ++ EET+ E
Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473
Query: 1696 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1755
++R L ++ + L R + QQ+ ++ +++A G + +
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533
Query: 1756 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1815
K+QL+ +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q
Sbjct: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591
Query: 1816 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1873
++ + DA R+R+ +E L + E QL R+ + + +R +
Sbjct: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651
Query: 1874 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1933
LK+ L +++ R D L++QL R ++ ++EE R + GR+ ++EL
Sbjct: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711
Query: 1934 DVTESAESMNREVTTLRNRLRR 1955
D +E + ++ + T+L N ++
Sbjct: 1712 DASERVQLLHTQNTSLINTKKK 1733
Score = 181 bits (458), Expect = 8e-45
Identities = 204/949 (21%), Positives = 411/949 (43%), Gaps = 98/949 (10%)
Query: 864 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 914
TK K LQ Q + LQ ++ + + + + ++V +L+G + Q LE +
Sbjct: 997 TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056
Query: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
+L L+ E + E + +L + ++ E +S L+ ++ +E+ + Q+Q + K LQ
Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1023
I+ELE +EAE +R K + ++ ++++ E L + + + ++
Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176
Query: 1024 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1065
K R+ LE+ + + AA E E++ SL +++ K E I D+
Sbjct: 1177 KMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLA 1236
Query: 1066 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1125
+ K + EK+ R L+ + SE++ + EQQ+ EL AQ R E + +
Sbjct: 1237 SNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLD 1296
Query: 1126 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1185
++ +QL + + + E + LE E A++ + + + LR + E+ +
Sbjct: 1297 EKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQE 1356
Query: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
+ Q SK EV + + E + ++E +++ Q L + E +E
Sbjct: 1357 AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCA 1416
Query: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1305
+ EKT+ L+ EV +L ++ A ++++R + L E + + + + A EA++
Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQ-AELEASQ 1475
Query: 1306 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1364
K R+ EL V A E+ L +E + + ++ D E + E + L +
Sbjct: 1476 KESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK 1535
Query: 1365 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1423
++ E + L+ LEE A+ E ++ Q +L++ + + + A E ++ +R
Sbjct: 1536 QLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHL 1595
Query: 1424 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL--------EQQRQLVST----- 1470
R E++ L + + + R +++++ +L++ + L E R L +T
Sbjct: 1596 RVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILK 1655
Query: 1471 -----LEKKQRKFDQL-----LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1520
L+ R D L + E +A +++A E RA E ER + + L +
Sbjct: 1656 DTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE--QELLDA 1713
Query: 1521 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1580
E + L QN +L + L + + + ++ + R AE+ A + +EL
Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773
Query: 1581 TAAEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDE 1632
+D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E +
Sbjct: 1774 KKEQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVES 1832
Query: 1633 ERKQRTLAVAARKKLEGELEELKAQ---------------------MASAGQGKEEAVKQ 1671
E+K AV +K E ++EL Q + + + EEA +Q
Sbjct: 1833 EQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQ 1892
Query: 1672 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720
A+ ++L E+EE + + ++++ ++ R+K E + EE
Sbjct: 1893 SNVNLAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939
Score = 135 bits (340), Expect = 4e-31
Identities = 170/785 (21%), Positives = 329/785 (41%), Gaps = 120/785 (15%)
Query: 1255 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAEL 1314
E E++ ++ E + + E +R+ LE ++ + D Q ++
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKND--------------LQLQV 895
Query: 1315 ENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLR 1374
+ + AL +AE + +L K EA++ + E ++E L ++ R +E E + L+
Sbjct: 896 QAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955
Query: 1375 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE--AGEEARRRAAREAEALT-Q 1431
+ +++ + +E + ++ + EE AG E A ++A +EA T
Sbjct: 956 KDIDDLELTLAKVEKEKHATENKV---KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012
Query: 1432 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1491
L + + V+ L + + +L+Q++DD LEQ+++L LE+ +RK + L + + +
Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072
Query: 1492 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1551
++++ + +++E +L +E+EQ +L+++ + L+A +E L ++++
Sbjct: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEEL---EEEI--- 1126
Query: 1552 VHELERACRV-AEQAANDLRAQVTELEDELT---AAEDAKLRLEVTVQALKTQHERDLQG 1607
E ERA R AE+ +DL ++ E+ + L A A++ + +A + RDL+
Sbjct: 1127 --EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184
Query: 1608 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1667
E L K+ D+ E E Q ++KLE E ELK ++ E
Sbjct: 1185 STLQHEATAAALRKKHADSVAELGE---QIDSLQRVKQKLEKEKSELKMEINDLASNMET 1241
Query: 1668 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1727
K + + L ++ E +T EE ++ + L A+ RL E S
Sbjct: 1242 VSKAKANFEKMCRTLEDQLSEIKTKEEE-------QQRLINELSAQKARLHTE---SGEF 1291
Query: 1728 RRQAQQDRDEMADEVANGNLSKAAILEE-KRQLEGRLGQ-----------------LEEE 1769
RQ + +D M +++ G + +EE KRQLE L E+
Sbjct: 1292 SRQLDE-KDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQ 1350
Query: 1770 LEEEQ------------SNSEL-----------------LNDRYRKLLLQVESLTTELSA 1800
EEEQ +NSE+ L + +KL +++ + A
Sbjct: 1351 YEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1410
Query: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKM------TIAALESKLAQAEEQ 1854
S A E +Q+L+ ++++L + +A A K +A + K + + +
Sbjct: 1411 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE 1470
Query: 1855 LEQETRE-RILSGKL----------------VRRAEKRLKEVVLQVEEERRVADQLRDQL 1897
LE +E R LS +L ++R K L++ + + E+ + +L
Sbjct: 1471 LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHEL 1530
Query: 1898 EKGNLRV----KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1953
EK ++ +L+ LEEAE + R+Q EL V + E ++L
Sbjct: 1531 EKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQL 1590
Query: 1954 RRGPL 1958
+R L
Sbjct: 1591 KRNHL 1595
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 1258 bits (3255), Expect = 0.0
Identities = 712/1887 (37%), Positives = 1118/1887 (59%), Gaps = 44/1887 (2%)
Query: 87 RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146
R L L DQ+ MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N
Sbjct: 68 RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127
Query: 147 PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206
PYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT
Sbjct: 128 PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187
Query: 207 NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266
NTK+VIQY A +A + +KE P + G LE Q++QANP+LEAFGNAKTV+NDN
Sbjct: 188 NTKRVIQYFATIAVTGDKKKETQ-PGKMQ----GTLEDQIIQANPLLEAFGNAKTVRNDN 242
Query: 267 SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326
SSRFGKFIRI+F G + A+IETYLLEKSR Q E S+HIFYQ++ +L D
Sbjct: 243 SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-ID 301
Query: 327 LLLEPCSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSA 379
LLL + + F P S G+ + E T ++ +LGFS EE + + ++ A
Sbjct: 302 LLLISTNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGA 357
Query: 380 VLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQ 439
V+ +GN+ K+++ +QA A K L+GL + + L PR+KVG +YV K Q
Sbjct: 358 VMHYGNMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQ 417
Query: 440 TKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSF 498
+Q ++ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS
Sbjct: 418 NVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSL 475
Query: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGL 558
EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL CI+LIE+P G+
Sbjct: 476 EQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GI 532
Query: 559 LALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKA 615
++L+EEC FPKATD SF K+ Q G FQ+P+ + +A+ FS++HYAG VDY
Sbjct: 533 FSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNI 592
Query: 616 NEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMF 675
WL KN DPLN+ V L +S+ +L + ++ + G + G GG+ + F
Sbjct: 593 AGWLDKNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----ETGDSGGSKKGGKKKGSSF 648
Query: 676 RTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRI 735
+TV +++E+L++LM L +T+P FVRC++PN K G ++ LV+ QLRCNGVLEGIRI
Sbjct: 649 QTVSAVFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRI 708
Query: 736 CRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIF 794
CR+GFP+RIL+ +F+QRY IL +AIP+G F+D K A EK++ ++++D +R G +K+F
Sbjct: 709 CRKGFPSRILYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVF 768
Query: 795 FRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKL 854
F+AG+L LEE RD K+ ++ S QA RGYL R F+K +++ ++ +Q N +++ +
Sbjct: 769 FKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNV 828
Query: 855 RHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEER 914
+HW W LF K+KPLL+ ++ + ++ ++ +E +S EL+ ++ L +E+
Sbjct: 829 KHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEK 888
Query: 915 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 974
L Q+++E E +AEE L K LE V EL R+ EEEE + ++ +K+ L+
Sbjct: 889 NDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLE 948
Query: 975 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1034
L+ ++ E K++ EK TE K+K E++ LE+ SKL+KE+K L++
Sbjct: 949 DKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQ 1008
Query: 1035 EFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQE 1094
+ EE+KV L K+ K E D+E L +E+K R +LE+ KR+L+G+ QE
Sbjct: 1009 QTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQE 1068
Query: 1095 QMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLES 1154
+++ + +++ +L +KE EL A+ +DE Q K ++E QA + E +E++E+
Sbjct: 1069 SIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEA 1128
Query: 1155 ERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
E R K EKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE T
Sbjct: 1129 EHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188
Query: 1215 HEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQE 1274
HEA LR++ ++ EL EQ++ +R K EK + L+ E+ ++ + + +L ++
Sbjct: 1189 HEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSN 1248
Query: 1275 GEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELEN--VSGALNEAESKTIRLS 1332
E+ R +E Q E+ +A D ++ + +Q+A+ + +N +S + E ES +L+
Sbjct: 1249 IERTCRTVEDQFSEI--KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLT 1306
Query: 1333 KELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQ 1392
K + QL + + ++EET+AK A+ +++ + LREQ EEE A+ R L
Sbjct: 1307 KSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALS 1366
Query: 1393 TAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVD----RLERGR 1447
A +++++WR + E +A E EEA+++ A+ Q E TET + LE+ +
Sbjct: 1367 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR----LQEAEENTETANSKCASLEKTK 1422
Query: 1448 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1507
+RLQ E++D DLE+ +TL+KKQR FD++LAE K + + E E A+ E R
Sbjct: 1423 QRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLS 1482
Query: 1508 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1567
+ A EE + E L R+N+ L+ E+ L + GK++ E E+ ++ EQ +
Sbjct: 1483 TELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKS 1542
Query: 1568 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1627
DL+ + E+E L E LR+++ + +K++ +R + +DE E+ +R + +
Sbjct: 1543 DLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQ 1602
Query: 1628 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1687
D E + R A+ +KK+EG+L E++ Q+ + + E K LR +Q Q+K+ ++
Sbjct: 1603 SVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLD 1662
Query: 1688 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1747
+ S E++ Q E+R L E+ ++ L ++R RR ++Q+ + +D V +
Sbjct: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722
Query: 1748 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1807
+++ K++LE + Q + E+E S ++ +K + + EL E+ SA
Sbjct: 1723 QNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1782
Query: 1808 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGK 1867
E ++ LE+ +++L+ RL E + A K I LE+++ + E +L+ E + + K
Sbjct: 1783 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALK 1842
Query: 1868 LVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRR 1927
+ E+++KE+ Q EE+ + +L+D ++K +VK KRQ EEAEE+A+ + RR
Sbjct: 1843 GAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRR 1902
Query: 1928 LQRELEDVTESAESMNREVTTLRNRLR 1954
+Q ELE+ E A+ +V LR + R
Sbjct: 1903 VQHELEEAAERADIAESQVNKLRAKSR 1929
Score = 214 bits (546), Expect = 5e-55
Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%)
Query: 1052 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1109
K++ ++ A+ E KE E+ ++EL + + R EL+E+MV Q +L+ Q
Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894
Query: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1169
+ + E L A R E L+KS +A + E E LE E ++ ++R+L
Sbjct: 895 VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947
Query: 1170 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1226
++ +L+ +++D TL ++ + + ++E LEE + L++ H
Sbjct: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007
Query: 1227 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1286
Q L +L Q+E+ + K LE + +L L + R + E+ +R+LE L
Sbjct: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063
Query: 1287 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1346
+ Q D E + + EKL++ + EL + +++ + +++ K++ +A++ + +
Sbjct: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123
Query: 1347 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1406
E ++ E + + + + E + E+LEE + A + +A+ + RR E
Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183
Query: 1407 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1466
E EA R+ ++ +AE E +D L+R +++L++E + M+++
Sbjct: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237
Query: 1467 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1519
+ L K + ++ E++ + ++A +E++ + L L+ +EE
Sbjct: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297
Query: 1520 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1579
++ +L + +AL +LE L ++ K+ + + A + + + LR Q E ++
Sbjct: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357
Query: 1580 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1639
+ A + V +T++E D R E EE +++LA++L++AE + +
Sbjct: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417
Query: 1640 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1699
+++L+GE+E+L + + K+ R + E ++++E++ E +
Sbjct: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477
Query: 1700 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1759
+R L + + ++L R + Q++ ++ +++A + + K+ +
Sbjct: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537
Query: 1760 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1819
E L+ LEE + + E + ++ L++ + +EL +R K E +QL+R
Sbjct: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594
Query: 1820 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1876
Q L DA R+R+ +E L + E QL R+ + K +R + +L
Sbjct: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654
Query: 1877 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1936
K+ L +++ R + L++QL R L +LEE + + + RR ++EL D +
Sbjct: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714
Query: 1937 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1984
+ + ++ + T+L N ++ ++E ++E+A++A
Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762
Score = 139 bits (349), Expect = 4e-32
Identities = 181/852 (21%), Positives = 343/852 (40%), Gaps = 195/852 (22%)
Query: 879 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL 938
LQA+ + ++V LQ Q +++ ELQ R+ +LEEE + AE L A+ E+ R L
Sbjct: 1094 LQAKIDD-EQVHSLQFQ--KKIKELQARIEELEEE-------IEAEHTLRAKIEKQRSDL 1143
Query: 939 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE----------- 987
A +E+ + E + E +++ + E +++++ ++E EA
Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADS 1203
Query: 988 -----------EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1036
+ +QKL+ EK + ++ ++ L S + + + +ED+ +E
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI 1263
Query: 1037 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1096
++ ++ + + LN + + + ++ R+ ++E +L K K+ L + EL+ QM
Sbjct: 1264 KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM 1323
Query: 1097 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESER 1156
E+ + + L + + E+E A+A+L ++L +A + +A+ + E++
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDA 1383
Query: 1157 VARTKA-EKQRRDLGEELEA---------------------LRGELEDTLD----STNAQ 1190
+ RT+ E+ ++ L + L+ L+GE+ED + S A
Sbjct: 1384 IQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTAC 1443
Query: 1191 QELRSKR---EQEVTELKKTLEEETRIHEAAVQELRQ------RHGQALGELAEQLEQAR 1241
L K+ ++ + E K+ L+E EAA +E R + A E+ +QLE R
Sbjct: 1444 ATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLR 1503
Query: 1242 R-------------------GKGAWE--KTRLALEAEVSELRAELSSLQTARQEGEQRRR 1280
R GK E KT+ +E E S+L+ L ++ + + E +
Sbjct: 1504 RENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKIL 1563
Query: 1281 RLELQLQEVQGRAGDGERARAEAAEKL----QRAQAELENV------------------S 1318
R++L+L +V+ + E E+L QRA L++V
Sbjct: 1564 RVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKME 1623
Query: 1319 GALNEAE-------SKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
G LNE E + K L + + QL D+Q L + R+ L ++ +E
Sbjct: 1624 GDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNG 1683
Query: 1372 GLREQLEEEAAARERAGRELQTAQAQLSE-----------------WRRRQEEEAGALEA 1414
L E+LEE A E+ R + ++ +L + +++ E + +A
Sbjct: 1684 LLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA 1743
Query: 1415 -----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 1463
EE ++A +A + + L ++ +T LER ++ L+Q + D L++
Sbjct: 1744 EVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803
Query: 1464 QRQL--------VSTLEKKQRKFDQLL---------------------------AEE--- 1485
QL + LE + R+ + L AEE
Sbjct: 1804 AEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHK 1863
Query: 1486 ------------KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRA 1533
+A V + E AE + + +R + LEE E + E Q
Sbjct: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNK 1923
Query: 1534 LRAELEALLSSK 1545
LRA+ + S K
Sbjct: 1924 LRAKSRDVGSQK 1935
Score = 116 bits (291), Expect = 2e-25
Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%)
Query: 861 RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 910
R+ K + Q+T+ + L + +EL++ E + QS+R +L Q
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351
Query: 911 EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 964
EEE+ AE RA ++ +E + R + R +ELE +L R+ E EE +
Sbjct: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411
Query: 965 -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1014
++ K+RLQ +++L LE A +++ +KV E K K E L
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471
Query: 1015 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1074
Q KE + L L + + E +++++L + + I+D+ +++ + K
Sbjct: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526
Query: 1075 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1134
QE EK K+ ++ E S+LQ + E + E +++ R + EL + + + + +
Sbjct: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586
Query: 1135 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1194
++ L+ AEA L+S A ++ L +++E E+E L +N Q
Sbjct: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643
Query: 1195 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1248
K + V +LK + L++ R +E ++L +R G L E+LE+ + E
Sbjct: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700
Query: 1249 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1308
+TR E E+ + + L + +++LE + + Q + + A EK +
Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760
Query: 1309 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1367
+A + ++ L + + + L + + E + D Q L E + L G + ++ +E
Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
Query: 1368 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1427
L +L+ E A + + ++ E + EE+ + ++ + + +
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880
Query: 1428 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1485
+ ++ E E + RR+Q EL++A + V+ L K R EE
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 1152 bits (2981), Expect = 0.0
Identities = 682/1917 (35%), Positives = 1077/1917 (56%), Gaps = 45/1917 (2%)
Query: 53 RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112
++ W+P + + A ++ ++ + G L + D+IQ+MNPP+F EDMA
Sbjct: 51 KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110
Query: 113 LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172
LT LNEASVLH L+ RY +IYTYSGLFCV INPYK LP+Y + ++ Y+GK+R E PP
Sbjct: 111 LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170
Query: 173 HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPA 232
H++AV A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+ + RK+ G
Sbjct: 171 HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228
Query: 233 SVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 292
LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F G + +I+ Y
Sbjct: 229 ---------LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIY 279
Query: 293 LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERE 351
LLEKSR I Q E ++HIFYQ+L G E L+ S + F + G + + E
Sbjct: 280 LLEKSRVIFQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAE 339
Query: 352 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 411
T +++ +LGF +E ++ A++ FGN+ K++ +Q A K L
Sbjct: 340 ELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFL 399
Query: 412 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 471
+G+ ++ + L+ PRIKVG +YV + QT EQ A+ AL+K+ YER+F+WLV R+NRAL
Sbjct: 400 MGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRAL 459
Query: 472 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 530
D + RQ F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN MFVLEQEEY++E
Sbjct: 460 DAKLSRQ--FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKES 517
Query: 531 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---H 587
I W + FGLDLQ CIDLIE+P G+L++L+EEC FPKATD +F K+ G H
Sbjct: 518 IEWVSIGFGLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVH 574
Query: 588 PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 647
+ +P + +A F ++HYAG V Y + WL KN D LN+ V A+ +S++RL A ++
Sbjct: 575 LQKPKPDKKKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF- 633
Query: 648 DVEGIVGLEQVSSLGDGPPGGRPRR---GMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 704
E S P G +R F+TV L+KE+L++LM L +T P FVRCI
Sbjct: 634 --------ENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCI 685
Query: 705 VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 764
PN K G L+P LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P PK
Sbjct: 686 NPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKS 745
Query: 765 -FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAAR 823
F+ ++A E+++ +LE+D YR G +K+FF+AG L QLE RD +++ + FQA A+
Sbjct: 746 KFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQ 805
Query: 824 GYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARA 883
G L R FQK +++ AL ++Q N A++ +++W W RLF K+KPL++ + E +
Sbjct: 806 GKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLK 865
Query: 884 QELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQ 943
+E ++Q+ ++S + EL+ + L +E+ L QL+AE E A EE L K
Sbjct: 866 EECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKI 925
Query: 944 ELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEA 1003
+LE V EL RV EEEE + ++ ++L+ EL+ ++ E K + EK TTE
Sbjct: 926 QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH 985
Query: 1004 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1063
K+K E++ L + SKL++ K++++ + EEEK+ SL+K LK E + +
Sbjct: 986 KVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDE 1045
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1123
+E L +E K R E+ +L+G +E M + L +L +KE EL ++
Sbjct: 1046 LEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSK 1105
Query: 1124 AEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDT 1183
E+E G AQL K+++E Q + + +E LE+ER R K E++R DL ++L L LE+
Sbjct: 1106 VENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEV 1165
Query: 1184 LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1243
S+ AQ E+ K+E + +L + +EE T E L++RH +L EL Q+E ++
Sbjct: 1166 GGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQV 1225
Query: 1244 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1303
K EK + L+ EV +L + + A+ E+ E +L E + + +
Sbjct: 1226 KQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDL 1285
Query: 1304 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1363
A + + +E L E E+ +LS+E S+ Q+ D + L++ET+++ AL +
Sbjct: 1286 AAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHAL 1345
Query: 1364 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRA 1422
+ + + LREQ EEE + R L A++ +WR + E E E+A++
Sbjct: 1346 QKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKEL 1405
Query: 1423 AREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLL 1482
A + + + LER R +LQ EL DA DL + R + L++KQ + + L
Sbjct: 1406 AIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKAL 1465
Query: 1483 AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEEEQEAREELERQNRALRAE 1537
A+ K E +A + ++E +ALS L EE +E L R+N+ L+ E
Sbjct: 1466 ADWKQK-----HEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEE 1520
Query: 1538 LEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1597
+ L + + K++ E+E+ ++ E+ +++ + E E L E L ++ +
Sbjct: 1521 ISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEA 1580
Query: 1598 KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQ 1657
K + ER L +DE E RR+ + + D E K R +KK+E +L E++ Q
Sbjct: 1581 KAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQ 1640
Query: 1658 MASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRL 1717
++ A + EA K L ++Q Q+K+L +++++ ++ Q +E+R L++E+ L
Sbjct: 1641 LSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDL 1700
Query: 1718 QEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS 1777
+ ++R RR ++++ E + + ++L +K++LE + ++++E EE
Sbjct: 1701 RSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQEC 1760
Query: 1778 ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARH 1837
+ ++ +K ++ +L+ EL ++ A E R+ +E+ I +L+ RL E + A
Sbjct: 1761 QNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGS 1820
Query: 1838 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQL 1897
+ I LES++ + E +LE E R + + RR E+ +KE+ Q EE+++ +++ Q+
Sbjct: 1821 RKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQM 1880
Query: 1898 EKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1954
+K L+V+ K+Q+E AE +A++ + ++ Q EL +V E AE +V L+ + R
Sbjct: 1881 DKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937
Score = 189 bits (479), Expect = 3e-47
Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%)
Query: 995 QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1051
QLE + E K F L KL K +K+LE+R A Q VK+
Sbjct: 784 QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840
Query: 1052 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1107
+RL ++ + +E G +E L+K + + + EL+ + V Q +L
Sbjct: 841 WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900
Query: 1108 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1167
QL ++E L + E L+KS + +A + E E +E E ++ + R
Sbjct: 901 LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953
Query: 1168 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1224
L +E L+ E++D L + ++ + + +TE + L E+ A + +++
Sbjct: 954 KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013
Query: 1225 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1284
H Q L +L + E+ + K L LE +V EL L + AR E+ +LE
Sbjct: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069
Query: 1285 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1344
L+ + + E ++ AE+L++ + EL ++ + + +L K + + Q+ D
Sbjct: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129
Query: 1345 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1401
+E L+ E TRAK+ R RA + + A L E+LEE + + + + +
Sbjct: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186
Query: 1402 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1460
R EE E + ++ ++ A + E + V +LE+ + LQ E+DD
Sbjct: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246
Query: 1461 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1520
+EQ + + EK +++ L E A + + + A+ + + + R LEE+
Sbjct: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306
Query: 1521 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1580
+ +L R+ ++E L + KS L A + A++ + LR Q E ++
Sbjct: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366
Query: 1581 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640
++ + + ++E ++ R E E+ +++LA +L++A +
Sbjct: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426
Query: 1641 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1700
AR +L+ EL + + + A +L + Q Q + + + + EE +
Sbjct: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479
Query: 1701 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1753
S+K ++ L E+L+L +E + + RR+ Q++ + ++V G + +
Sbjct: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539
Query: 1754 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1810
+ K+ +E +++ LEE + E + + L Q+E L + ER S K E+
Sbjct: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597
Query: 1811 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1868
R++ + I L+ L D+ A++R ++T +E L + E QL R+ + K
Sbjct: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654
Query: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928
+ + + ++K++ +Q+++ ++ L++Q+ R L+ +LE+ + + GRR
Sbjct: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714
Query: 1929 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983
+ EL + TE + T+L ++ ++ R EE V + AEE
Sbjct: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 557 bits (1435), Expect = e-158
Identities = 453/1517 (29%), Positives = 733/1517 (48%), Gaps = 153/1517 (10%)
Query: 56 VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106
VW+P + +A L EG++ ++ L E L P D +QR NP
Sbjct: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70
Query: 107 AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165
D+ L+ L+E +VLHNL+ R+ S IYTY G+ V INPY+QLPIY + ++ Y G+
Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130
Query: 166 KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225
++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S
Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGS---- 186
Query: 226 KEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIV 285
S +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+
Sbjct: 187 -----------ASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHII 235
Query: 286 GANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS 345
GAN+ TYLLEKSR + QA DE ++HIFYQL AG +L L + + + G +S
Sbjct: 236 GANMRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTS 295
Query: 346 --PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDN 402
+ E F++T ++ +LG +S+ ++++++L G++A++ ER+ D ++ P +
Sbjct: 296 IEGVDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQD 355
Query: 403 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 462
CRLLG+ + L ++ + K + +Q A ALAK Y +LF W
Sbjct: 356 VYLSNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGW 415
Query: 463 LVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLE 522
+V +N+AL S +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LE
Sbjct: 416 IVEHINKALHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLE 474
Query: 523 QEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQ 582
QEEY +E IPWT +DF D QPCIDLIE G+L LLDEEC PK TD+++ +K+
Sbjct: 475 QEEYMKEQIPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYD 530
Query: 583 EQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 642
FQ+PR F ++H+A KV+Y ++ +L KN D + + +L S L
Sbjct: 531 RHSSSQHFQKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLV 588
Query: 643 AEIWKD--------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLS 694
A+++ D G ++S PP + +TVG ++ SL LM TL+
Sbjct: 589 ADLFHDDKDPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLN 648
Query: 695 NTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYE 754
T P +VRCI PN EK +P+ + QLR GVLE IRI G+P+R + +F RY
Sbjct: 649 ATTPHYVRCIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYR 708
Query: 755 ILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDI 814
+L D K C +++ L DP+ ++ G++KIFFRAG +A LE+ R K
Sbjct: 709 VLVKKR-ELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTA 767
Query: 815 IVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLR-------------HWQWWR 861
+ Q RG+L + K + + A +QR C +L R + +R
Sbjct: 768 TIMIQKTVRGWLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYR 824
Query: 862 LFTKVKPLLQVTRQDEVLQA--RAQELQKV--QELQQQSAREVGE-LQGRVAQLEEERAR 916
+ + +V R V+QA RA +++ Q L + A + + ++G +A+ +R R
Sbjct: 825 MQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLR 884
Query: 917 LA--------EQLRAEAELCAEAEETRG--RLAARKQELELVVSELEARVGEEEE----C 962
A L+A EL A E R L +E V +L+ ++ E+ +
Sbjct: 885 DAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTL 944
Query: 963 SRQMQTEKKRLQQHIQELEAHL-----EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1017
S Q+ ++ L+ L E +LQ E + ++++ + +LED
Sbjct: 945 SEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILED 1004
Query: 1018 QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQE 1077
+ S+E+ L R+A+ + A +++ + LN L + KE ++E
Sbjct: 1005 AH---SREKDELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKE 1059
Query: 1078 LEKLKRRLDGESSELQEQMVEQQQRAEELRAQL--------GRKEEELQAALARAEDEGG 1129
LE+ + R L ++ + +QR + LR ++ R+ Q++L E +
Sbjct: 1060 LEEERSRY----QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSL---ESDSN 1112
Query: 1130 ARAQLLKSLREAQAALAEAQE-DLESERVART---KAEKQRRDLGEELEALRGELE--DT 1183
+ + + + AL + +E LE + T K +K+ R+L +E + L+ +LE +
Sbjct: 1113 YPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQ 1172
Query: 1184 LDSTNAQQE-------LRSKREQEVTELKK-TLEEETRIHEAAVQELRQRHGQALGELAE 1235
DS Q E L + LK+ LE E + + + ELR+ +A+
Sbjct: 1173 QDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRK-------AVAD 1225
Query: 1236 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD 1295
Q Q G+ + L L+ L+ A +E E R+ E+ + Q + D
Sbjct: 1226 QATQNNSSHGSPDSYSLL-----------LNQLKLAHEELEVRKE--EVLILRTQIVSAD 1272
Query: 1296 GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRA 1355
R AE A++ N +++ ++ I + T ++ D L ++
Sbjct: 1273 QRRLAGRNAEPNINARSSWPNSEKHVDQEDA--IEAYHGVCQTNSKTEDWGYLNEDG--- 1327
Query: 1356 KLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE---EAGAL 1412
LG + ++ A L QL+ ++ E L+ L E +Q++ + L
Sbjct: 1328 --ELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLL 1385
Query: 1413 EAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVS 1469
+ +E LT + E V++LE+ R+L+++L DLE + L
Sbjct: 1386 SPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQ 1445
Query: 1470 TLEKKQRKFDQLLAEEK 1486
+ K+ Q+ + K
Sbjct: 1446 SERKRHELNRQVTVQRK 1462
Score = 53.1 bits (126), Expect = 3e-06
Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%)
Query: 1341 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1400
++ A++ Q RA + + + RAM + +E +A T Q +
Sbjct: 824 RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873
Query: 1401 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1456
W R+ +A + +A RE +AL A E + RL G ++ ++
Sbjct: 874 WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929
Query: 1457 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1516
+++Q + TL ++ L+ + VE ++ ++ SL R
Sbjct: 930 LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981
Query: 1517 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1576
EE + R EL+R + + +A KD++ K V +LE+ + + L Q+
Sbjct: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038
Query: 1577 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1636
L ++D + V +K + E + R + L K+ E D R +
Sbjct: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087
Query: 1637 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1696
T+ K+ G Q + ++ ++ ++VEE + +
Sbjct: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141
Query: 1697 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1747
+ + +KR++ LE E +LQ E+ D + QA+ D D AD +A +L
Sbjct: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200
Query: 1748 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1804
+ + E ++L+ L +L + + ++ Q+NS + D Y LL Q++ EL +
Sbjct: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260
Query: 1805 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1858
+ Q + + L GR E + AR+ +H A+E+ + + E
Sbjct: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318
Query: 1859 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1918
+ + A + LK+V R + QL+ Q + V+ LK QLE +EE
Sbjct: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372
Query: 1919 SRAQ 1922
+ Q
Sbjct: 1373 DKQQ 1376
Score = 47.8 bits (112), Expect = 1e-04
Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%)
Query: 1073 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
K R+EL+ L R++ S+E L+ V + + +L+ ++ + +E +
Sbjct: 898 KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943
Query: 1132 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1189
L + L + E L+ E V ++ E L EE+E+LR EL+
Sbjct: 944 --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001
Query: 1190 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1249
++ S+ + E+ + LE+E + + E Q + Q L + ++ Q + +K
Sbjct: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058
Query: 1250 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1309
E+ E R+ +L + EQR L ++ ++ G
Sbjct: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101
Query: 1310 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1365
N S +++ +I S E+ TE L +E+ E+ L L RVR
Sbjct: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155
Query: 1366 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1425
+E E L+ QLE+ R ++ + QA+ + + A L R+ E
Sbjct: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208
Query: 1426 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1485
+ L L E + V D ++ L Q + LE ++ + L +
Sbjct: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268
Query: 1486 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1541
+A ++ R E A S E+ + + +E + + +
Sbjct: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322
Query: 1542 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1586
L+ ++G + L++ R+ E + L+AQ+ L++E+ +
Sbjct: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382
Query: 1587 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1638
+ ++E VQ + T DL+ E E+ R+L KQL+ + + +
Sbjct: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442
Query: 1639 LAVAARKKLE 1648
LA + RK+ E
Sbjct: 1443 LAQSERKRHE 1452
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 546 bits (1407), Expect = e-155
Identities = 436/1414 (30%), Positives = 688/1414 (48%), Gaps = 133/1414 (9%)
Query: 50 WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103
+T VW+P +++A + + G++ + L E G L P NP
Sbjct: 7 YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65
Query: 104 FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162
D+ L+ L+E +VLHNLR R+ S LIYTYSG+ V +NPYKQLPIY +AI+ Y
Sbjct: 66 LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125
Query: 163 RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222
G+ ++ PH++AV E AY+ M ++ +QSI+ +GESGAGKT + + ++Y A V+ S
Sbjct: 126 SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSG 185
Query: 223 KGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAG 282
S +E ++L +NPI EA GNAKT +NDNSSRFGK+ I+FD
Sbjct: 186 ---------------SNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQN 230
Query: 283 YIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGP 342
I+GAN+ TYLLEKSR + Q+++E ++HIFYQL A + L L + + G
Sbjct: 231 QIIGANMSTYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGG 290
Query: 343 SS--SPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMP 400
++ +R ET ++ +LGF + + + ++++A+L GN+ + N +
Sbjct: 291 NTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSE 350
Query: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLF 460
D++ + C LLGL ++ L +I + V K T+ QA A +ALAK Y LF
Sbjct: 351 DDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLF 410
Query: 461 RWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFV 520
++V R+N+AL S +Q +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN +F
Sbjct: 411 DFIVERINQALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFK 469
Query: 521 LEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKV 580
LEQEEY +E IPWT +DF D QP IDLIE G+L LLDEEC P TD+++++K+
Sbjct: 470 LEQEEYMKEDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKL 525
Query: 581 AQE-QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTD 639
+P F++PR F + H+A KV+YK +L KN D + D + +L S
Sbjct: 526 YNNFVNRNPLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKF 583
Query: 640 RLTAEIWKDVEGIVG-LEQVSSLGDGPPGGRPRRGMFR-TVGQLYKESLSRLMATLSNTN 697
L A +++ + ++ +P FR TVG ++ SL LM TL+ T
Sbjct: 584 HLCANFFQENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATT 643
Query: 698 PSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILT 757
P +VRCI PN EK + + + ++ QLR GVLE IRI Q +P+R + EF RY IL
Sbjct: 644 PHYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILM 703
Query: 758 PNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVS 817
F D K+ C+ ++ L D N Y+ G++KIFFRAG +A LE+ R K+ V
Sbjct: 704 TKQ-ELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVM 762
Query: 818 FQAAARGYLARRAFQKRQQ-----------QQS--------------ALRVMQRNCAAYL 852
Q RG+L R+ F + ++ QQ+ A ++Q++C YL
Sbjct: 763 VQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYL 822
Query: 853 KLRHWQWWRLFTKV-----KPLLQVTRQDEVLQA-RAQELQKVQE--------------- 891
+Q R+ T + L R ++L+ +A LQK
Sbjct: 823 VRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFV 882
Query: 892 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 951
L Q V LQ ++ +E L E+L + A L A E +K E EL +
Sbjct: 883 LNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVE-----KIQKLEAELEKAA 937
Query: 952 LEARVGEEEECSRQMQTEKK--RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFE 1009
R EE+ + E+K +LQ+H ELE E + +L+L++ T E K +K +
Sbjct: 938 THRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKE-----QIQLKLQEKTEELK-EKMD 991
Query: 1010 EDLLLLEDQNSKLSKERKLLED----RLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD-- 1063
L D K ++R LLE + ++ Q +E++K+L +++ + +
Sbjct: 992 NLTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEH 1051
Query: 1064 -MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1122
D L+ E + K + E LQ Q ++ ++ + + ++ K E+ L
Sbjct: 1052 VTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLL 1111
Query: 1123 RAEDEGGARAQL----LKSLREAQAALAEAQEDL-ESERVARTKAEKQRRDLGEELEALR 1177
+ D R++L L+ L E L A E L ++ RV + + Q+ +E+EAL
Sbjct: 1112 ESYDIEDVRSRLSVEDLEHLNE-DGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALN 1170
Query: 1178 GELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ--RHGQALGELAE 1235
++ QE+ L+K EE I+E+ E+ + + + +
Sbjct: 1171 FKVVHL--------------SQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQ 1216
Query: 1236 QLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ-EVQGRAG 1294
Q+ + + K E RL +AE + + E S Q R + E+ +R L+ Q E+
Sbjct: 1217 QISELEKQKQDLE-IRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIH---- 1271
Query: 1295 DGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETR 1354
+ + + +K+Q Q +++ +E S + D +E L + R
Sbjct: 1272 --TKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDR 1329
Query: 1355 AKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1388
L +V+ + ++ G + + +E G
Sbjct: 1330 VIKKLQDQVKTL-SKTIGKANDVHSSSGPKEYLG 1362
Score = 70.1 bits (170), Expect = 2e-11
Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%)
Query: 1475 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1532
+R++ ++L E KA +L+ R + R + LT + Q +++LE QN+
Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903
Query: 1533 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1592
+E L S V ++++ E+AA R + + A E+ +L+
Sbjct: 904 ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963
Query: 1593 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1643
L+TQ E+ LQ + E +E+ L KQL D +V+++E +QR L +
Sbjct: 964 HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020
Query: 1644 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1688
K+++ EE+KA Q G + V +L K + E +E+E
Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
Query: 1689 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1741
+ + + + SQ RE +++ + ++L E D R + +D + + ++
Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137
Query: 1742 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1787
A L KA +LE E L ++ L +E+ Q ND +
Sbjct: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
Query: 1788 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1847
+V LT+E F + +LE+Q Q+L RL E+ + K + L ++
Sbjct: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249
Query: 1848 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1907
L +++E+ E R+ + + + EK ++++ +++E + +D L+ Q E + VK
Sbjct: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305
Query: 1908 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1949
RQ EASR R L+ EL+ + + +V TL
Sbjct: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
Score = 67.0 bits (162), Expect = 2e-10
Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%)
Query: 1099 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1158
Q R L QL + + LQ L E + L SL +A E + LE+E
Sbjct: 876 QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933
Query: 1159 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1218
KA RR+ E+ + R +E+ L Q+ S+ E + +++ L+E+T
Sbjct: 934 -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983
Query: 1219 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1278
+EL+++ +L + +++ R + EK+ E + + ++ SL+ + +
Sbjct: 984 -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039
Query: 1279 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338
+ +L+ L E + DG +A K + +E E KE+
Sbjct: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081
Query: 1339 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1395
+AQ D ++ +Q E R K++ ++ + +R +L E EL A
Sbjct: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141
Query: 1396 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1454
L + R LE+ ++++ +E EAL ++ ++ ++ L++ L +E
Sbjct: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190
Query: 1455 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1513
+D + + +++ F Q ++E EK + E+AE + E + L
Sbjct: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250
Query: 1514 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1566
R+ EEE R+ LE QN E E L+ ++ ++ L++ Q A
Sbjct: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
Query: 1567 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1597
+ L + +LE+EL + +L+ V+ L
Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341
Score = 57.0 bits (136), Expect = 2e-07
Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%)
Query: 871 QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 930
Q+ E ++A E ++Q L + L+ VA+L ++ ++E + L A+
Sbjct: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084
Query: 931 AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 986
+ + ++K+E+ +SE+ ++ E S ++ + RL +H+ E A
Sbjct: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140
Query: 987 EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1043
EG ++ ++ + +++ +E+++ L + LS+E L+ E + E
Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200
Query: 1044 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1100
++ S N + ++ I+++E + + E + ++ EK+K +L+ S++L E+ Q
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260
Query: 1101 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1152
++A E + ++ KE +E+Q A + + +++ + R+ + L DL
Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320
Query: 1153 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1200
E E + + K+ +D + L G+ D S+ ++ L+ KRE E
Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 543 bits (1399), Expect = e-154
Identities = 462/1477 (31%), Positives = 721/1477 (48%), Gaps = 122/1477 (8%)
Query: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
Query: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
S +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GA
Sbjct: 187 ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
Query: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
N+ TYLLEKSR + QA++E ++HIFYQL A L L ++ + G P
Sbjct: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297
Query: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
+ + T ++ +LG S + + R+++ +L GN+ R+ D T+P
Sbjct: 298 GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356
Query: 406 QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
+ C L+G+ + L ++ + K +K QA A +ALAK Y +LF W+V
Sbjct: 357 LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416
Query: 465 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
+N+AL + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQE
Sbjct: 417 DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
Query: 525 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
EY +E IPWT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+
Sbjct: 476 EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
Query: 585 -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
F++PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++
Sbjct: 532 LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
Query: 644 EIWKDVEGIVGLEQVSSLG--------DGPPGGRP---RRGMFRTVGQLYKESLSRLMAT 692
E+++D E + +S G P GRP + +TVG ++ SL LM T
Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649
Query: 693 LSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQR 752
L+ T P +VRCI PN K + + + QLR GVLE IRI GFP+R +QEF R
Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709
Query: 753 YEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVT 812
Y +L D KQ C+ +++ L LD + Y+ G++KIFFRAG +A LE+ R K+
Sbjct: 710 YRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLR 767
Query: 813 DIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQV 872
+ Q RG+L R+ K + + A MQR Y + R + + TK ++Q
Sbjct: 768 AACIRIQKTIRGWLLRK---KYLRMRKAAITMQRYVRGY-QARCYAKFLRRTKAATIIQK 823
Query: 873 TRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAE 932
+ V++ R ++++ + QS L+G +A R R + LR + + +
Sbjct: 824 YWRMYVVR-RRYKIRRAATIVLQS-----YLRGFLA-----RNRYRKILREHKAVIIQ-K 871
Query: 933 ETRGRLAAR--KQELELVVSELEARVGEEEECSRQM--QTEKKRLQQHIQELEAHLEAEE 988
RG LA K+ + ++ + C R+M + E K+L+ + +E + +
Sbjct: 872 RVRGWLARTHYKRSMHAII--------YLQCCFRRMMAKRELKKLKIEARSVERYKKLHI 923
Query: 989 GARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QNSKLSKERKLLEDRLAEFSSQAAEEE 1044
G K +QL++ E K E L LE NS+ K R LE RL Q +EEE
Sbjct: 924 GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLE-RL-----QLSEEE 977
Query: 1045 EKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE-LEKLKRRLDGESSELQEQMVEQQQR 1102
KV + L L+ E A + ++ R E+K +E ++ K+ + S L+E+ +Q
Sbjct: 978 AKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQE 1037
Query: 1103 AEELRAQLGRKEEELQAALARAEDEGGARAQL--------LKSLREAQAALAEAQEDLES 1154
E L ++ ++ +E+ + + E + +L ++L + L E +DL+
Sbjct: 1038 KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKE 1097
Query: 1155 ERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
E K + + E E S A+ E R +E +E K L+ +
Sbjct: 1098 EMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFL 1156
Query: 1215 H-EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR-AELSSLQTAR 1272
+ V EL Q EL + EQ R K A E E ++R AEL R
Sbjct: 1157 KLQKRVTELEQEKQVMQDELDRKEEQVLRSK--------AKEEERPQIRGAELEYESLKR 1208
Query: 1273 QEGEQRRRRLELQLQEVQGRAGD--GERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1330
QE E ++L+ +L E++ + A A + +L +VS L+ + + +
Sbjct: 1209 QELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
Query: 1331 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1390
L +QL +E +Q + S + + + + ++ + + R
Sbjct: 1269 L-------RSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRL 1321
Query: 1391 LQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAREAEALTQ--RLAEKTETVDRLERGR 1447
L ++QL +R E EA AL + + R+ + L Q +L + L+
Sbjct: 1322 L---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEI 1378
Query: 1448 RRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1484
RL E D LE+Q + V L+K+ + F + + E
Sbjct: 1379 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415
Score = 66.6 bits (161), Expect = 2e-10
Identities = 129/620 (20%), Positives = 244/620 (39%), Gaps = 106/620 (17%)
Query: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
Query: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1304
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
Query: 1305 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
Query: 1363 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1418
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Query: 1419 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1478
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
Query: 1479 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1538
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
Query: 1539 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK 1598
L + + KS E+ A L Q+T + +EL ++ L L L
Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILR---SQLV 1274
Query: 1599 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE-ERKQRTLAVAARKKLEGELEELKAQ 1657
+Q E +Q +D+ + L D + +D+ E Q + + +L L++Q
Sbjct: 1275 SQKEA-IQPKDDKNTMTDSTIL--LEDVQKMKDKGEIAQAYIGLKETNRL------LESQ 1325
Query: 1658 MASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKG------ 1709
+ S + E + LR +KE E R ++++ +QN + E R++
Sbjct: 1326 LQSQKRSHENEAEALRGEIQSLKE-----ENNR--QQQLLAQNLQLPPEARIEASLQHEI 1378
Query: 1710 --LEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GNLSKAAILEE------ 1755
L E L L E+L D+ R+ ++ A ++ N+S I++E
Sbjct: 1379 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVN 1438
Query: 1756 -KRQLEGRLGQLEEELEEEQ 1774
R+ + G LE + E+EQ
Sbjct: 1439 IPRKEKDFQGMLEYKKEDEQ 1458
Score = 65.1 bits (157), Expect = 7e-10
Identities = 103/551 (18%), Positives = 229/551 (41%), Gaps = 92/551 (16%)
Query: 1431 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
++L + +V+R ++ ++ ++ +++Q + L +K + + E +
Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965
Query: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGK 1550
+E + +E E + R LSL +EE+ + LR +LE S K K
Sbjct: 966 SDLERLQLSEEEAKVATGRVLSL----------QEEIAK----LRKDLEQTRSEK----K 1007
Query: 1551 SVHE-LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRD 1609
+ E +R + EQ ++L+ + T L+ E A + R +Q
Sbjct: 1008 CIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL-----------------NHRIVQQAK 1050
Query: 1610 EAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA------SAGQ 1663
E E ++L ++ + E++ ++ER + + +LE ++LK +M G
Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGH 1110
Query: 1664 GKEEAVKQLRKMQ-------AQMKELWREVEETRTSREEI-FSQNRESEKRLKGLEAEVL 1715
+ ++ + + A+M+++ EE + + S + +KR+ LE E
Sbjct: 1111 KRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ 1170
Query: 1716 RLQEELAASD----RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1771
+Q+EL + R++ + ++ E+ +L + + E ++L+ L +L + L
Sbjct: 1171 VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230
Query: 1772 EEQSNSELLNDR--YRKLLLQVESLTTELSAERS----FSAKAESGRQQLE--------- 1816
E+ + YR L+ Q+ S++ EL + ++ S ++ ++
Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT 1290
Query: 1817 ------RQIQELR--GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1868
+Q+++ G + + G + +++ + L+S+ E + E R I S K
Sbjct: 1291 DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEA-LRGEIQSLKE 1349
Query: 1869 VRRAEKRLKEVVLQVEEERRVADQLR--------------DQLEKGNLRVKQLKRQLEEA 1914
+++L LQ+ E R+ L+ +QLEK + V++LK+QL+
Sbjct: 1350 ENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVF 1409
Query: 1915 EEEASRAQAGR 1925
++ + G+
Sbjct: 1410 AKKIGELEVGQ 1420
Score = 41.6 bits (96), Expect = 0.008
Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%)
Query: 1759 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1818
+E ++ QL+ +++E+ + + L VE LT + E ++++ E R LER
Sbjct: 925 MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971
Query: 1819 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1878
+L EE+A + +L+ ++A+ + LEQ E+ + R ++ ++
Sbjct: 972 ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022
Query: 1879 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1938
+V ++EE + Q ++ L N R+ Q +++ E E+ + ++L+ +L D
Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077
Query: 1939 AESMNREVTTLRNR 1952
+++ E + L R
Sbjct: 1078 YQNLLNEFSRLEER 1091
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 541 bits (1393), Expect = e-153
Identities = 468/1497 (31%), Positives = 728/1497 (48%), Gaps = 135/1497 (9%)
Query: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108
VW+P +++A L + + +V L E G+ L D + NP
Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72
Query: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+
Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S
Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGS------ 186
Query: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
S +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GA
Sbjct: 187 ---------ASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
Query: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSS 345
N+ TYLLEKSR + QA++E ++HIFYQL A L L ++ + G P
Sbjct: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIE 297
Query: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAA 405
+ + T ++ +LG S + + R+++ +L GN+ R+ D T+P
Sbjct: 298 GVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEP 356
Query: 406 QKL-CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLV 464
+ C L+G+ + L ++ + K +K QA A +ALAK Y +LF W+V
Sbjct: 357 LCIFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIV 416
Query: 465 LRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQE 524
+N+AL + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQE
Sbjct: 417 DNVNQALHSAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQE 475
Query: 525 EYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ 584
EY +E IPWT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+
Sbjct: 476 EYMKEQIPWTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTH 531
Query: 585 -GGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
F++PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++
Sbjct: 532 LNKCALFEKPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLP 589
Query: 644 EIWKDVEGIVGLEQVSSLG--------DGPPGGRP---RRGMFRTVGQLYKESLSRLMAT 692
E+++D E + +S G P GRP + +TVG ++ SL LM T
Sbjct: 590 ELFQDDEKAISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMET 649
Query: 693 LSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQR 752
L+ T P +VRCI PN K + + + QLR GVLE IRI GFP+R +QEF R
Sbjct: 650 LNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSR 709
Query: 753 YEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVT 812
Y +L D KQ C+ +++ L LD + Y+ G++KIFFRAG +A LE+ R K+
Sbjct: 710 YRVLMKQ--KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLR 767
Query: 813 DIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQV 872
+ Q RG+L R+ K + + A MQR Y + R + + TK ++Q
Sbjct: 768 AACIRIQKTIRGWLLRK---KYLRMRKAAITMQRYVRGY-QARCYAKFLRRTKAATIIQK 823
Query: 873 TRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAE 932
+ V++ R ++++ + QS L+G +A R R + LR + + +
Sbjct: 824 YWRMYVVR-RRYKIRRAATIVLQS-----YLRGFLA-----RNRYRKILREHKAVIIQ-K 871
Query: 933 ETRGRLAAR--KQELELVVSELEARVGEEEECSRQM--QTEKKRLQQHIQELEAHLEAEE 988
RG LA K+ + ++ + C R+M + E K+L+ + +E + +
Sbjct: 872 RVRGWLARTHYKRSMHAII--------YLQCCFRRMMAKRELKKLKIEARSVERYKKLHI 923
Query: 989 GARQK-LQLEKVTTEAK--MKKFEEDLLLLED-QNSKLSKERKLLEDRLAEFSSQAAEEE 1044
G K +QL++ E K E L LE NS+ K R LE RL Q +EEE
Sbjct: 924 GMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLE-RL-----QLSEEE 977
Query: 1045 EKVKSLNKLRLKYE-ATIADMEDRLRKEEKGRQE-LEKLKRRLDGESSELQEQMVEQQQR 1102
KV + L L+ E A + ++ R E+K +E ++ K+ + S L+E+ +Q
Sbjct: 978 AKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQE 1037
Query: 1103 AEELRAQLGRKEEELQAALARAEDEGGARAQL--------LKSLREAQAALAEAQEDLES 1154
E L ++ ++ +E+ + + E + +L ++L + L E +DL+
Sbjct: 1038 KEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKE 1097
Query: 1155 ERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1214
E K + + E E S A+ E R +E +E K L+ +
Sbjct: 1098 EMTLMVHVPKPGHKRTDSTHS-SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFL 1156
Query: 1215 H-EAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR-AELSSLQTAR 1272
+ V EL Q EL + EQ R K A E E ++R AEL R
Sbjct: 1157 KLQKRVTELEQEKQVMQDELDRKEEQVLRSK--------AKEEERPQIRGAELEYESLKR 1208
Query: 1273 QEGEQRRRRLELQLQEVQGRAGD--GERARAEAAEKLQRAQAELENVSGALNEAESKTIR 1330
QE E ++L+ +L E++ + A A + +L +VS L+ + + +
Sbjct: 1209 QELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLI 1268
Query: 1331 LSKELSSTEAQ----------------LHDAQELLQEETRAKLALG----SRVRAMEAEA 1370
L +L S + L D Q++ + A+ +G +R A++
Sbjct: 1269 LRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHE 1328
Query: 1371 AGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAREAEAL 1429
+L ++A R L ++QL +R E EA AL + + R+ + L
Sbjct: 1329 LNEDGELWLVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLL 1385
Query: 1430 TQ--RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1484
Q +L + L+ RL E D LE+Q + V L+K+ + F + + E
Sbjct: 1386 AQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442
Score = 77.4 bits (189), Expect = 1e-13
Identities = 141/606 (23%), Positives = 240/606 (39%), Gaps = 133/606 (21%)
Query: 1336 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1391
S TE D + L E AK+A G RV +++ E A LR+ LE E+ E A R
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017
Query: 1392 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1451
Q + +S + EE L+ +EA + Q+ E TET+++ +L
Sbjct: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEK------KLV 1061
Query: 1452 QELDDATMDLEQQR----QLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1507
+E +DL +R L++ + + ++D L E V +R ++ E
Sbjct: 1062 EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNE 1121
Query: 1508 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1567
+ + + E E E + + ++ L
Sbjct: 1122 SEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK------------------------ 1157
Query: 1568 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1627
L+ +VTELE E +D R E V R +A EE R Q+R AE
Sbjct: 1158 -LQKRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAE 1200
Query: 1628 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1687
+E + ++Q + KKL+ EL EL+ ++ K ++ A +R +
Sbjct: 1201 LEYESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLM 1249
Query: 1688 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1747
E TS E +E EVL L+ +L + A Q + D++ M D
Sbjct: 1250 EQLTSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI---- 1294
Query: 1748 SKAAILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAE 1801
+LE+ ++++ G + Q L+E +S L LN+ +L L E L A
Sbjct: 1295 ----LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QAN 1346
Query: 1802 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1861
R ++ +S ++ E + + LRG I +L+ E ++
Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQ 1382
Query: 1862 RILSGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEAS 1919
++L+ L E R+ E LQ E R + L +QLEK + V++LK+QL+ ++
Sbjct: 1383 QLLAQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIG 1441
Query: 1920 RAQAGR 1925
+ G+
Sbjct: 1442 ELEVGQ 1447
Score = 63.5 bits (153), Expect = 2e-09
Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%)
Query: 1186 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1245
S ++L E ++ +L++ ++E+ + ++ V++L G
Sbjct: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955
Query: 1246 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1304
+E +LR++L LQ + +E + R+ +E+ D E+ R+E
Sbjct: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008
Query: 1305 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
E R + E E + L E + L +E + ++ + + E KL ++
Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065
Query: 1363 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1418
++ LR Q L E + ER +E T + + ++ + + E
Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125
Query: 1419 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1478
E E + R E +E L D ++ L+ Q+++ ++KQ
Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173
Query: 1479 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1538
D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL
Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222
Query: 1539 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1594
L + + KS E+ A L Q+T + +EL ++ L L +
Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
Query: 1595 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1641
+A++ + ++ D+Q + GE + L + R + ++ E + L +
Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
Query: 1642 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1692
A + LE +L+ K A A +G+ +++K+ Q Q+ L + ++ +
Sbjct: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395
Query: 1693 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1746
R E Q+ + L E L L E+L D+ R+ ++ A ++ N
Sbjct: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450
Query: 1747 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1774
+S I++E R+ + G LE + E+EQ
Sbjct: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485
Score = 41.6 bits (96), Expect = 0.008
Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%)
Query: 1759 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1818
+E ++ QL+ +++E+ + + L VE LT + E ++++ E R LER
Sbjct: 925 MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971
Query: 1819 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1878
+L EE+A + +L+ ++A+ + LEQ E+ + R ++ ++
Sbjct: 972 ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022
Query: 1879 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1938
+V ++EE + Q ++ L N R+ Q +++ E E+ + ++L+ +L D
Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077
Query: 1939 AESMNREVTTLRNR 1952
+++ E + L R
Sbjct: 1078 YQNLLNEFSRLEER 1091
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 533 bits (1373), Expect = e-151
Identities = 441/1667 (26%), Positives = 782/1667 (46%), Gaps = 170/1667 (10%)
Query: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
Query: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
Query: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
Query: 225 RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
K V + + +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 524 NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
Query: 285 VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
A+I+T LLEK R R+ E +F++FY LL L+ +L L + P +
Sbjct: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
Query: 345 SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
P ++++ F + +++VLG S +E + +++A+ G A K +
Sbjct: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
Query: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
+ AQK LLG + + S A+ + K G +Q++ + Q A
Sbjct: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
Query: 445 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
LE +A Y LF LV +NRAL S S + I+D GF+ + SF
Sbjct: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
Query: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
E+LC NYT ++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
Query: 557 ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
GLL LL+EE P A++ + +E++ G G K Q P H F
Sbjct: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
Query: 603 SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG-------- 651
+ H G V+Y WL +P N LL S ++ + ++ G
Sbjct: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
Query: 652 IVGLEQVSSLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVR 702
I GLE S L R F T + + K+SL L+ T+ + FV
Sbjct: 988 IAGLEGGSQLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045
Query: 703 CIVPNHEKRAGK-----------------------------LEPRLVLDQLRCNGVLEGI 733
C +P E AG+ L+ L+ QLR + +L+ +
Sbjct: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105
Query: 734 RICRQGFPNRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRV 788
R+ RQG+P+ ++F EFR+R+++L P+ K +D ++A E++++ L+L+ + +
Sbjct: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165
Query: 789 GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC 848
G S++FFRAG LA+LEE+RD + + + FQAA RGYLAR+ F+KR+ Q A+R +Q+N
Sbjct: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225
Query: 849 AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA 908
++ W WW+LFT V+PL++V +E ++ + +E+Q+++ +++ +E EL+
Sbjct: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSD 1285
Query: 909 QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT 968
+LE + L +L E A + A + E + EL+ + + +QM+
Sbjct: 1286 RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT---QYDALKKQMEV 1342
Query: 969 EKKRLQQH--IQELEAHLEAEE---GARQKLQLEKVT-----TEAKMKKFEEDLLLLEDQ 1018
+ + + I+ E + E ++ G +L+ E+ T+ ++++ ED L +E Q
Sbjct: 1343 MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ 1402
Query: 1019 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1078
N ++ LE RL + + + E + ++ L K + A + D + L ++ EL
Sbjct: 1403 N------KRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHEL 1456
Query: 1079 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 1138
EK +RR D E S+ E+ ++ + E+L+ + E + + E++ A + +
Sbjct: 1457 EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV 1516
Query: 1139 REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE 1198
+A L + + + K +KQ RDL +++ EL++ + ++ + + E
Sbjct: 1517 VSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLE 1576
Query: 1199 QEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEV 1258
E+ +++T +E + V+E RQ + L ++ QLE+ K + + LE ++
Sbjct: 1577 MEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
Query: 1259 SELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVS 1318
+ L S Q R++ E +RL L+ + D + + + ++ E+ +
Sbjct: 1637 ATL-----SDQVNRRDFES-EKRLRKDLKRTKALLADAQ-LMLDHLKNSAPSKREIAQLK 1689
Query: 1319 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 1378
L E+E K + E ++ D + + +AK AL ++ ++ E ++ +LE
Sbjct: 1690 NQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749
Query: 1379 EE-----------AAARERAGREL---QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1424
E+ AA +A R+L QAQL E + ++E L+A +
Sbjct: 1750 EDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS------- 1802
Query: 1425 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1484
+ E L Q + +K+ V R E R L+ L+ +++ L S L++ K + +
Sbjct: 1803 QVEFLEQSMVDKS-LVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQ 1861
Query: 1485 EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSS 1544
AA R E+ +R + + R+ + L R E + ELE +L A ++L +
Sbjct: 1862 RIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1921
Query: 1545 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE 1591
K + +L+ A E +++ + L+D +T + K +LE
Sbjct: 1922 LKLAFKRIGDLQAAIE-DEMESDENEDLINSLQDMVTKYQKRKNKLE 1967
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1279 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
Query: 1339 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1378
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1379 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1435
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
Query: 1436 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1495
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
Query: 1496 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1555
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 1556 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1615
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
Query: 1616 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1675
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
Query: 1676 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1735
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1658 LKRTKALLADAQ----LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
Query: 1736 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1795
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 1796 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1855
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
Query: 1856 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1913
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1832 EFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
Query: 1914 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1946
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Score = 157 bits (396), Expect = 1e-37
Identities = 164/804 (20%), Positives = 350/804 (43%), Gaps = 121/804 (15%)
Query: 1093 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1152
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1153 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1194
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1195 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
Query: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1431
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
Query: 1432 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
Query: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1543
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
Query: 1544 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1593
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
Query: 1594 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1647
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
Query: 1648 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1691
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
Query: 1692 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1751
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1811
+ + + R+G L+ +E+E +D L+ ++ + T+ ++
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEME-----SDENEDLINSLQDMVTKYQKRKNKLEGDSDV 1972
Query: 1812 RQQLERQIQELRGRLGEEDAGARA 1835
+LE ++ ++ L + ++A
Sbjct: 1973 DSELEDRVDGVKSWLSKNKGPSKA 1996
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
Query: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1583
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
Query: 1584 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
Query: 1641 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1698
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
Query: 1699 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1751
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
Query: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1810
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
Query: 1811 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1868
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
Query: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
Query: 1929 QRELEDVTESAESMNREVTTLRNRLRR 1955
+ E+ED+ + + + T L +L R
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Score = 109 bits (272), Expect = 3e-23
Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%)
Query: 1395 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1448
+ QLSE + R ++E LE E+ R ++ L R++E T E D G
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 1449 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1504
Q +D E +L + E K Q ++D L + + + +E R AE G
Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1505 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1548
ER R + T+ L++E E + E+E+QN R L L L + ++
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 1549 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1608
+++ +L++ C+ D + + + E + R + + + +R+ R
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 1609 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1666
++ E+ LA+ +++ E K +A +K LE EL+++ +Q +
Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Query: 1667 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1723
+ KQLR ++A++K+ E++E + + + E +R++ ++ + ++E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
+ AR+ Q+ +M ++ K +L EKR+LEG+L L +++ SE R
Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
RK L + ++L + + + R+I +L+ +L E + T AA
Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
+A + +E E + L + +A+ L+E + +++ E+ ++++++LE+
Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1953
+ +L ++ + A +ASR A LQ +LE+ + + + ++ L++++
Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804
Score = 59.3 bits (142), Expect = 4e-08
Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%)
Query: 1684 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1743
R + E + S E+I +++ E ++ LE E SDR + + E+ DE
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303
Query: 1744 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1803
G S + +L+ + E L E+ E L +Y L Q+E + E+ R
Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352
Query: 1804 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1863
A E+ G + ++DAG R K A E +++L+QE +++
Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397
Query: 1864 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1908
+ + R+ E+RL ++ EE +R QL+ + LE +R +L+
Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Query: 1909 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1961
+ +L +A EEA R + R +LQRE + + A S+ +++ + FT
Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513
Query: 1962 TRTVRQVFRLEEGVASDEEAEEA 1984
+ V L++ ++S E +EA
Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 528 bits (1360), Expect = e-149
Identities = 441/1675 (26%), Positives = 782/1675 (46%), Gaps = 175/1675 (10%)
Query: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
Query: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
Query: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
Query: 225 RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
K V + + +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 524 NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
Query: 285 VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
A+I+T LLEK R R+ E +F++FY LL L+ +L L + P +
Sbjct: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
Query: 345 SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
P ++++ F + +++VLG S +E + +++A+ G A K +
Sbjct: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
Query: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
+ AQK LLG + + S A+ + K G +Q++ + Q A
Sbjct: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
Query: 445 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
LE +A Y LF LV +NRAL S S + I+D GF+ + SF
Sbjct: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
Query: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
E+LC NYT ++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
Query: 557 ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
GLL LL+EE P A++ + +E++ G G K Q P H F
Sbjct: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
Query: 603 SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG-------- 651
+ H G V+Y WL +P N LL S ++ + ++ G
Sbjct: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
Query: 652 IVGLEQVSSLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVR 702
I GLE S L R F T + + K+SL L+ T+ + FV
Sbjct: 988 IAGLEGGSQLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045
Query: 703 CIVPNHEKRAGK-----------------------------LEPRLVLDQLRCNGVLEGI 733
C +P E AG+ L+ L+ QLR + +L+ +
Sbjct: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105
Query: 734 RICRQGFPNRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRV 788
R+ RQG+P+ ++F EFR+R+++L P+ K +D ++A E++++ L+L+ + +
Sbjct: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165
Query: 789 GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC 848
G S++FFRAG LA+LEE+RD + + + FQAA RGYLAR+ F+KR+ Q A+R +Q+N
Sbjct: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225
Query: 849 AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA 908
++ W WW+LFT V+PL++V +E ++ + +E+Q+++ +++ +E EL+
Sbjct: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSD 1285
Query: 909 QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT 968
+LE + L +L E A + A + E + EL+ + + +QM+
Sbjct: 1286 RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT---QYDALKKQMEV 1342
Query: 969 EKKRLQQH--IQELEAHLEAEE---GARQKLQLEKVT-----TEAKMKKFEEDLLLLEDQ 1018
+ + + I+ E + E ++ G +L+ E+ T+ ++++ ED L +E Q
Sbjct: 1343 MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ 1402
Query: 1019 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1078
N ++ LE RL + + + E + ++ L K + A + D + L ++ EL
Sbjct: 1403 N------KRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHEL 1456
Query: 1079 EKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSL 1138
EK +RR D E S+ E+ ++ + E+L+ + E + + E++ A + +
Sbjct: 1457 EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKV 1516
Query: 1139 REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE 1198
+A L + + + K +KQ RDL +++ EL++ + ++ + + E
Sbjct: 1517 VSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLE 1576
Query: 1199 QEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEV 1258
E+ +++T +E + V+E RQ + L ++ QLE+ K + + LE ++
Sbjct: 1577 MEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
Query: 1259 SELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVS 1318
+ L S Q R++ E +RL L+ + D + + + ++ E+ +
Sbjct: 1637 ATL-----SDQVNRRDFES-EKRLRKDLKRTKALLADAQ-LMLDHLKNSAPSKREIAQLK 1689
Query: 1319 GALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE 1378
L E+E K + E ++ D + + +AK AL ++ ++ E ++ +LE
Sbjct: 1690 NQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749
Query: 1379 EE-----------AAARERAGREL---QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1424
E+ AA +A R+L QAQL E + ++E L+A +
Sbjct: 1750 EDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS------- 1802
Query: 1425 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1484
+ E L Q + +K+ V R E R L+ L+ +++ L S L++ K + +
Sbjct: 1803 QVEFLEQSMVDKS-LVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQ 1861
Query: 1485 EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSS 1544
AA R E+ +R + + R+ + L R E + ELE +L A ++L +
Sbjct: 1862 RIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1921
Query: 1545 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1599
K + +L+ A + ++ +D + E + D LE V +K+
Sbjct: 1922 LKLAFKRIGDLQAA--IEDEMESDENEDLINSEGD----SDVDSELEDRVDGVKS 1970
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1279 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
Query: 1339 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1378
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1379 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1435
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
Query: 1436 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1495
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
Query: 1496 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1555
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 1556 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1615
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
Query: 1616 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1675
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
Query: 1676 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1735
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
Query: 1736 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1795
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
Query: 1796 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1855
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
Query: 1856 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1913
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
Query: 1914 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1946
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
Score = 156 bits (394), Expect = 2e-37
Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)
Query: 1093 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1152
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
Query: 1153 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1194
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
Query: 1195 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
Query: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
Query: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1431
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
Query: 1432 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
Query: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1543
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
Query: 1544 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1593
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
Query: 1594 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1647
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
Query: 1648 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1691
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
Query: 1692 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1751
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
Query: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSE 1778
+ + + R+G L+ +E+E + E
Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
Query: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1583
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
Query: 1584 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
Query: 1641 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1698
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
Query: 1699 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1751
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
Query: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1810
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
Query: 1811 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1868
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
Query: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
Query: 1929 QRELEDVTESAESMNREVTTLRNRLRR 1955
+ E+ED+ + + + T L +L R
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
Score = 109 bits (272), Expect = 3e-23
Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%)
Query: 1395 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1448
+ QLSE + R ++E LE E+ R ++ L R++E T E D G
Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
Query: 1449 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1504
Q +D E +L + E K Q ++D L + + + +E R AE G
Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Query: 1505 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1548
ER R + T+ L++E E + E+E+QN R L L L + ++
Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
Query: 1549 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1608
+++ +L++ C+ D + + + E + R + + + +R+ R
Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
Query: 1609 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1666
++ E+ LA+ +++ E K +A +K LE EL+++ +Q +
Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Query: 1667 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1723
+ KQLR ++A++K+ E++E + + + E +R++ ++ + ++E
Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597
Query: 1724 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1783
+ AR+ Q+ +M ++ K +L EKR+LEG+L L +++ SE R
Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653
Query: 1784 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1843
RK L + ++L + + + R+I +L+ +L E + T AA
Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701
Query: 1844 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1903
+A + +E E + L + +A+ L+E + +++ E+ ++++++LE+
Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754
Query: 1904 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1953
+ +L ++ + A +ASR A LQ +LE+ + + + ++ L++++
Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804
Score = 59.3 bits (142), Expect = 4e-08
Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%)
Query: 1684 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1743
R + E + S E+I +++ E ++ LE E SDR + + E+ DE
Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303
Query: 1744 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1803
G S + +L+ + E L E+ E L +Y L Q+E + E+ R
Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352
Query: 1804 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1863
A E+ G + ++DAG R K A E +++L+QE +++
Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397
Query: 1864 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1908
+ + R+ E+RL ++ EE +R QL+ + LE +R +L+
Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Query: 1909 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1961
+ +L +A EEA R + R +LQRE + + A S+ +++ + FT
Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513
Query: 1962 TRTVRQVFRLEEGVASDEEAEEA 1984
+ V L++ ++S E +EA
Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 476 bits (1224), Expect = e-133
Identities = 320/944 (33%), Positives = 513/944 (54%), Gaps = 61/944 (6%)
Query: 91 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ 150
+ ++ M+P +DMA LT L+ S+++NL +RY IYTY G +NPY+
Sbjct: 49 ITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQP 108
Query: 151 LP-IYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTK 209
+ +Y A +E Y + E+PPH++A+ YR + + ++Q IL +GESGAGKTE+TK
Sbjct: 109 IAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTK 168
Query: 210 KVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSR 269
++++L+ ++ E + S V ER +L+++PI+EAFGNAKTV N+NSSR
Sbjct: 169 LILKFLSVISQQSL---ELSLKEKTSCV-----ERAILESSPIMEAFGNAKTVYNNNSSR 220
Query: 270 FGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLL 329
FGKF+++N G I G I YLLEK+R +RQ E ++HIFY LL G + + + L
Sbjct: 221 FGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYL 280
Query: 330 EPCSHYRFLTNG--PSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIA 387
+Y +L ++E F+E + ++ V+ FS EE+ + R+++ +L GNI
Sbjct: 281 STPENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE 340
Query: 388 LKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFA 447
A + TA + LLGL T + AL + + + + +QA +
Sbjct: 341 F---ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDS 397
Query: 448 LEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTN 507
++LA A Y F W++ ++N + + +GILDI GFE F++N FEQ INY N
Sbjct: 398 RDSLAMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYAN 455
Query: 508 EKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECW 567
EKLQ+ FN +F LEQ EY REG+ W +D+ +D C+DLIE+ GLLAL++EE
Sbjct: 456 EKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESH 511
Query: 568 FPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLN 627
FP+ATD + +EK+ + + + +PR + +F V HYAG+V Y L KN D
Sbjct: 512 FPQATDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFR 569
Query: 628 DNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 687
D++ LL +S +++ E + +L G RP TV +K+SL
Sbjct: 570 DDLLNLLRESRFDFIYDLF---EHVSSRNNQDTLKCGSKHRRP------TVSSQFKDSLH 620
Query: 688 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 747
LMATLS++NP FVRCI PN +K + + +VL+QLR +G+LE +RI + G+ R FQ
Sbjct: 621 SLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQ 680
Query: 748 EFRQRYEILTPN-AIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEE 806
+F +RY++L N A+P+ D + C ++Q + + +++G++K+F R + +LE+
Sbjct: 681 DFYKRYKVLMRNLALPE---DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKR 737
Query: 807 RDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKV 866
R+ +V+ + +A G+LAR+ ++K + ++Q+N A+L R R
Sbjct: 738 REEEVSHAAMVIRAHVLGFLARKQYRK---VLYCVVIIQKNYRAFLLRR-----RFLHLK 789
Query: 867 KPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAE 926
K + +Q AR Q + E ++Q ++ E + + + EEER R E+ R EAE
Sbjct: 790 KAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER--ERERREAE 847
Query: 927 LCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE-LEAHLE 985
L A+ EE RKQ+ ELEA ++E + EK++ + ++E L E
Sbjct: 848 LRAQQEE-----ETRKQQ------ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKE 896
Query: 986 AEEGARQKLQLEKVTTEAKMKKFEE----DLLLLEDQNSKLSKE 1025
E+ R K Q E TEA ++K +E +L LE++ + ++E
Sbjct: 897 IEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940
Score = 53.5 bits (127), Expect = 2e-06
Identities = 70/233 (30%), Positives = 113/233 (48%), Gaps = 31/233 (13%)
Query: 1348 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ-E 1406
++Q+ RA L L R ++ A ++QL + A R R+L A+ + E +++Q E
Sbjct: 771 IIQKNYRAFL-LRRRFLHLKKAAIVFQKQLRGQIA--RRVYRQL-LAEKREQEEKKKQEE 826
Query: 1407 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1466
EE E E R R REAE Q+ E R QQEL +A +++ +
Sbjct: 827 EEKKKREEEERERERERREAELRAQQEEE------------TRKQQEL-EALQKSQKEAE 873
Query: 1467 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA-LEEEQEAR- 1524
L LEK++ ++ +LR +E E + R +E + LSLT A L++ QE R
Sbjct: 874 LTRELEKQKEN------KQVEEILRLEKEIEDLQ---RMKEQQELSLTEASLQKLQERRD 924
Query: 1525 EELER-QNRALRAELEALLS-SKDDVGKSVHELERACRVAEQAANDLRAQVTE 1575
+EL R + A RA E L S + D++ + V +ER+ V + +++L E
Sbjct: 925 QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACE 977
Score = 47.0 bits (110), Expect = 2e-04
Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 12/148 (8%)
Query: 992 QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1051
++L EK E K K+ EE+ E++ + +ER R AE +Q EE K + L
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERER-----REAELRAQQEEETRKQQELE 863
Query: 1052 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1111
L+ + A++ L K+++ +Q E L RL+ E +LQ +++QQ A L
Sbjct: 864 ALQKSQKE--AELTRELEKQKENKQVEEIL--RLEKEIEDLQR--MKEQQELSLTEASLQ 917
Query: 1112 RKEEELQAALARAEDEGGARAQ-LLKSL 1138
+ +E L R E+E AQ L+SL
Sbjct: 918 KLQERRDQELRRLEEEACRAAQEFLESL 945
Score = 45.8 bits (107), Expect = 4e-04
Identities = 36/141 (25%), Positives = 74/141 (52%), Gaps = 12/141 (8%)
Query: 1104 EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAE 1163
++LR Q+ R+ A R ++E + + K RE + E +E E+E A+ + E
Sbjct: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE-RERREAELRAQQEEE 855
Query: 1164 KQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE--------EETRIH 1215
+++ +ELEAL+ ++ + +++ +K+ +E+ L+K +E +E +
Sbjct: 856 TRKQ---QELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLT 912
Query: 1216 EAAVQELRQRHGQALGELAEQ 1236
EA++Q+L++R Q L L E+
Sbjct: 913 EASLQKLQERRDQELRRLEEE 933
Score = 43.9 bits (102), Expect = 0.002
Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 20/156 (12%)
Query: 1772 EEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDA 1831
++Q ++ YR+LL + + E K E ++ ER+ +E R +E+
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEE- 854
Query: 1832 GARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE----R 1887
E++ Q E L++ +E L+ +L ++ E + E +L++E+E +
Sbjct: 855 -------------ETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ 901
Query: 1888 RVADQLRDQLEKGNLRVKQLKR--QLEEAEEEASRA 1921
R+ +Q L + +L+ Q +R +L EEEA RA
Sbjct: 902 RMKEQQELSLTEASLQKLQERRDQELRRLEEEACRA 937
Score = 43.9 bits (102), Expect = 0.002
Identities = 41/177 (23%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Query: 1054 RLKYEATIADMEDRLRK-----EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1108
R Y +A+ ++ K EEK ++E E+ +R + +EL+ Q E+ ++ +EL A
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA 864
Query: 1109 -QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1167
Q +KE EL L + ++ + ++ + + + + Q E + ++ T+A Q+
Sbjct: 865 LQKSQKEAELTRELEKQKEN-----KQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL 919
Query: 1168 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1224
+ E R E E AQ+ L S E+ E + +E + EL +
Sbjct: 920 QERRDQELRRLEEE---ACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973
Score = 43.9 bits (102), Expect = 0.002
Identities = 54/182 (29%), Positives = 90/182 (49%), Gaps = 38/182 (20%)
Query: 1064 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG---RKEEELQAA 1120
+ ++ +EEK +QE E+ K+R E +E+ E+++R ELRAQ RK++EL+A
Sbjct: 812 LAEKREQEEKKKQEEEEKKKR------EEEERERERERREAELRAQQEEETRKQQELEA- 864
Query: 1121 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEAL-RGE 1179
L KS +EA E +LE ++ + E R L +E+E L R +
Sbjct: 865 -------------LQKSQKEA-----ELTRELEKQKENKQVEEILR--LEKEIEDLQRMK 904
Query: 1180 LEDTLDSTNAQ-QELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE 1238
+ L T A Q+L+ +R+QE+ + LEEE AA + L + + E +E
Sbjct: 905 EQQELSLTEASLQKLQERRDQEL----RRLEEEA--CRAAQEFLESLNFDEIDECVRNIE 958
Query: 1239 QA 1240
++
Sbjct: 959 RS 960
Score = 42.0 bits (97), Expect = 0.006
Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%)
Query: 1560 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ- 1618
++A + L A+ E E++ E+ K + E + + + R+ + R + EE R+Q
Sbjct: 802 QIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQ 860
Query: 1619 ----LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1674
L K ++AE+ R+ E+++ V +LE E+E+L+ EA L+K
Sbjct: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA--SLQK 918
Query: 1675 MQAQMKELWREVEE--TRTSREEIFSQN 1700
+Q + + R +EE R ++E + S N
Sbjct: 919 LQERRDQELRRLEEEACRAAQEFLESLN 946
Score = 41.2 bits (95), Expect = 0.010
Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 19/139 (13%)
Query: 1145 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1204
LAE +E + E+ + + EK++R+ EE E R E L AQQE ++++QE+ L
Sbjct: 812 LAEKRE--QEEKKKQEEEEKKKRE-EEERERERERREAEL---RAQQEEETRKQQELEAL 865
Query: 1205 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1264
+K+ +E E Q+ ++ + L L +++E +R K E EL
Sbjct: 866 QKSQKEAELTRELEKQKENKQVEEIL-RLEKEIEDLQRMK------------EQQELSLT 912
Query: 1265 LSSLQTARQEGEQRRRRLE 1283
+SLQ ++ +Q RRLE
Sbjct: 913 EASLQKLQERRDQELRRLE 931
Score = 40.4 bits (93), Expect = 0.018
Identities = 64/262 (24%), Positives = 113/262 (43%), Gaps = 26/262 (9%)
Query: 1568 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1627
D+R + T L +L A +++ +L T L+ E+ L+ R E + +
Sbjct: 698 DVRGKCTSLL-QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756
Query: 1628 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1687
+ R + RK V +K L L+ + + KQLR A
Sbjct: 757 LARKQYRKVLYCVVIIQKNYRAFL--LRRRFLHLKKAAIVFQKQLRGQIA---------- 804
Query: 1688 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1747
R ++ ++ RE E++ K E E + +EE +R RR+A+ R + +E
Sbjct: 805 --RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAEL-RAQQEEETRKQQE 861
Query: 1748 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1807
+A +K Q E +L ELE+++ N ++ + +L ++E L + ++ S
Sbjct: 862 LEAL---QKSQKE---AELTRELEKQKENKQV--EEILRLEKEIEDL-QRMKEQQELSLT 912
Query: 1808 AESGRQQLERQIQELRGRLGEE 1829
S ++ ER+ QELR RL EE
Sbjct: 913 EASLQKLQERRDQELR-RLEEE 933
Score = 38.9 bits (89), Expect = 0.051
Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 11/138 (7%)
Query: 1026 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY-EATIADMEDRLRKEEKGRQELEKL-KR 1083
R+LL ++ + + EEEEK K + R + E A++ + +E + +QELE L K
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS 868
Query: 1084 RLDGESSELQEQMVEQQQRAEELR-------AQLGRKEEELQAALARAEDEGGARAQLLK 1136
+ + E + E+ E +Q E LR Q ++++EL A + R Q L+
Sbjct: 869 QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELR 928
Query: 1137 SLREAQAALAEAQEDLES 1154
L E A AQE LES
Sbjct: 929 RLEE--EACRAAQEFLES 944
Score = 38.1 bits (87), Expect = 0.087
Identities = 33/128 (25%), Positives = 66/128 (51%), Gaps = 12/128 (9%)
Query: 1820 QELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEV 1879
++LRG++ AR ++ +A E + + +++ E+E +++ + R E+R E+
Sbjct: 797 KQLRGQI------ARRVYRQLLA--EKREQEEKKKQEEEEKKKREEEERERERERREAEL 848
Query: 1880 VLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESA 1939
Q EEE R +L + L+K + +L R+LE+ +E + RL++E+ED+
Sbjct: 849 RAQQEEETRKQQEL-EALQKSQ-KEAELTRELEKQKENKQVEEI--LRLEKEIEDLQRMK 904
Query: 1940 ESMNREVT 1947
E +T
Sbjct: 905 EQQELSLT 912
Score = 37.7 bits (86), Expect = 0.11
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
Query: 1214 IHEAAVQELRQRHGQALGE-----LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL 1268
+ +AA+ +Q GQ LAE+ EQ + K E+ + E E R +
Sbjct: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
Query: 1269 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1328
A+QE E R+++ +L+ +Q + E R +K + E+ + + + +
Sbjct: 848 LRAQQEEETRKQQ---ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--R 902
Query: 1329 IRLSKELSSTEAQLHDAQELLQEETR 1354
++ +ELS TEA L QE +E R
Sbjct: 903 MKEQQELSLTEASLQKLQERRDQELR 928
Score = 37.0 bits (84), Expect = 0.19
Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 30/157 (19%)
Query: 1339 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1398
E + + ++ +EE + K R R E A LR Q EEE
Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET----------------- 856
Query: 1399 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1458
R+Q+E LEA +++++ A E Q+ ++ E + RLE+ LQ+ +
Sbjct: 857 ----RKQQE----LEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE 908
Query: 1459 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1495
+ L + ++L+K Q + DQ L + RA +E
Sbjct: 909 LSLTE-----ASLQKLQERRDQELRRLEEEACRAAQE 940
Score = 33.5 bits (75), Expect = 2.1
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 1868 LVRRAEKRLKE--VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1925
L+RR LK+ +V Q + ++A ++ QL ++ K+Q EE +++ + R
Sbjct: 780 LLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER 839
Query: 1926 RRLQRELEDVTESAESMNR--EVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1983
R +RE E + E + E+ L+ + LT ++ ++EE + ++E E+
Sbjct: 840 ERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIED 899
Query: 1984 AQ 1985
Q
Sbjct: 900 LQ 901
Score = 32.7 bits (73), Expect = 3.7
Identities = 24/125 (19%), Positives = 58/125 (46%), Gaps = 13/125 (10%)
Query: 1861 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1920
++ L G++ RR ++L + EE+++ Q ++ +K ++ +R+ EAE A +
Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKK---QEEEEKKKREEEERERERERREAELRAQQ 852
Query: 1921 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1980
+ R++ + E ++ + RE+ + + V ++ RLE+ + +
Sbjct: 853 EEETRKQQELEALQKSQKEAELTRELEKQKE----------NKQVEEILRLEKEIEDLQR 902
Query: 1981 AEEAQ 1985
+E Q
Sbjct: 903 MKEQQ 907
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 457 bits (1176), Expect = e-128
Identities = 299/835 (35%), Positives = 445/835 (53%), Gaps = 57/835 (6%)
Query: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167
EDM +L L E +VL NL+ R+ LIYTY G V +NPY+ IY V+ Y G+
Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284
Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227
E PPH++AV A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + +
Sbjct: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343
Query: 228 PGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 287
+ ++L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA
Sbjct: 1344 ---------------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGA 1387
Query: 288 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--S 345
YLLEKSR + QAK+E ++HIFY+LL G QL+ L+ Y +L G + +
Sbjct: 1388 ITSQYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIA 1447
Query: 346 PGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQ--ATMPDNT 403
+ + F+ L ++ VLGFS E+ S+ R+++++L GN+ ++ Q A++
Sbjct: 1448 GKSDADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAR 1507
Query: 404 AAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWL 463
Q + LL + +A+ + R+ + T E A A +A+AK Y LF WL
Sbjct: 1508 EIQAVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWL 1567
Query: 464 VLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQ 523
+ R+N + SPRQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQ
Sbjct: 1568 ITRVNALV--SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQ 1625
Query: 524 EEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE 583
EEY RE I W + F D QPCI+LI P G+L +LD++C FP+ATD +F++K
Sbjct: 1626 EEYIREQIDWQEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYH 1682
Query: 584 QGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTA 643
G +P + +P+ +F++ HYAGKV Y+ +++L KN D + +V L +S R+ A
Sbjct: 1683 HGANPLYSKPK--MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVA 1740
Query: 644 EIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRC 703
++ Q + G R TV +++SL L+ + NP F+RC
Sbjct: 1741 HLFSS-----HAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRC 1795
Query: 704 IVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPK 763
+ PNH+K G EP +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A+
Sbjct: 1796 LKPNHKKEPGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKH 1853
Query: 764 GFMDGKQACEKMIQAL-ELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 822
C ++ L ++ PN+YRVG SK+F + + LE R+ + ++ Q
Sbjct: 1854 DLPANGDMCVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCL 1913
Query: 823 RGYLARRAFQKRQQQQSALRVMQRNCAAYL-KLRHWQWWRLFTKVKPLLQV--------- 872
RG+ +R F+ + + + ++Q YL + R+ Q R K + L+
Sbjct: 1914 RGFFIKRRFRSLRHK---IILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLK 1970
Query: 873 TRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 927
R + Q L + +EL ++ VG L E A LA L+A A L
Sbjct: 1971 LRAEWRCQVEGALLWEQEELSKREVVAVGHL--------EVPAELAGLLQAVAGL 2017
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 456 bits (1174), Expect = e-128
Identities = 304/948 (32%), Positives = 491/948 (51%), Gaps = 75/948 (7%)
Query: 99 MNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAI 158
M+P +DM L LNEA ++HNL RY IYTY+G V +NP++ LP+YT
Sbjct: 59 MHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQ 118
Query: 159 VEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHV 218
V++Y + E+PPHV+A+ Y SM +++ DQ + +GESGAGKTE TK ++Q+LA +
Sbjct: 119 VQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATI 178
Query: 219 ASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF 278
+ + +E+Q+L+ANPILEAFGNAKT++NDNSSRFGK+I I F
Sbjct: 179 SGQ-----------------HSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYF 221
Query: 279 DVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFL 338
+ +G I GA IE +LLEKSR RQA +E ++HIFY +L G + K L L S Y +L
Sbjct: 222 NPSGVIEGARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYL 281
Query: 339 TNGPSSSPG--QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRE--RNT 394
T G +S + + + ++++L FS E ++++++A+L GN+ N
Sbjct: 282 TMGNCTSCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENL 341
Query: 395 DQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKA 454
D + + + A + +LL + + L+ I + ++V ++ QA +A K
Sbjct: 342 DASDVMETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKG 401
Query: 455 TYERLFRWLVLRLNRALDRSPRQGAS----FLGILDIAGFEIFQLNSFEQLCINYTNEKL 510
Y LF W+V ++N A+ P Q +G+LDI GFE F+ NSFEQLCIN+ NE L
Sbjct: 402 IYGHLFLWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHL 461
Query: 511 QQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPK 570
QQ F +F +EQEEY+ E I W ++ + D +P +DL+ P +++LLDEE FP+
Sbjct: 462 QQFFVQHVFTMEQEEYRSENISWDYIHY-TDNRPTLDLL--ALKPMSIISLLDEESRFPQ 518
Query: 571 ATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNV 630
TD + ++K+ + F +P+++ D A F + H+AG+V Y+A +L KN D L+ ++
Sbjct: 519 GTDLTMLQKLNSVHANNKAFLQPKNIHD-ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDI 577
Query: 631 AALLHQSTDRLTAEIWK----DVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESL 686
L++ S ++ EI+ + + G + + G+ T+G +K+SL
Sbjct: 578 LTLVYSSKNKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSL 637
Query: 687 SRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILF 746
+LM L+N P F+RCI PN K+ + L L QLR +G++E + I + GFP R F
Sbjct: 638 DQLMKILTNCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTF 697
Query: 747 QEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNL-YRVGQSKIFFRAGVLAQLEE 805
+EF QR+ +L PNA+ + I + L + ++ G++KIF R LE
Sbjct: 698 EEFSQRFGVLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEV 757
Query: 806 ERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRL-FT 864
+R + +S Q RGY R+ F ++++ L+ R Y R+++ + F
Sbjct: 758 QRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWR---GYCNRRNFKLILVGFE 814
Query: 865 KVKPLLQ---VTRQDEVLQARAQELQK------VQELQQQSAREVGELQGRVAQLEEERA 915
+++ + + + RQ + ++ R +LQ V++ Q R V +Q + R
Sbjct: 815 RLQAIARSQPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRN 874
Query: 916 RLAEQLRAEAELCAEAEETRGRLAARKQE-----------LELVVSELEARVGEEEECSR 964
+ A + AE ++++G L A+K+ +E V L A +G +E
Sbjct: 875 FQQRKANAPLVIPAEGQKSQGALPAKKRRSIYDTVTDTEMVEKVFGFLPAMIGGQE---- 930
Query: 965 QMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1012
+ H E E QKL + T ++ EED+
Sbjct: 931 -------------GQASPHFEDLESKTQKLLEVDLDTVPMAEEPEEDV 965
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 453 bits (1165), Expect = e-127
Identities = 354/1160 (30%), Positives = 554/1160 (47%), Gaps = 122/1160 (10%)
Query: 96 IQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYT 155
I+ M+P EDM L LNEA +L NL RY LIYTY+G V +NPY+ L IY+
Sbjct: 56 IKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYS 115
Query: 156 EAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYL 215
+ Y KK E+PPH++A+ + Y +M ++ DQ + +GESGAGKTE+TK ++Q+L
Sbjct: 116 PEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL 175
Query: 216 AHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIR 275
A ++ + +E+Q+L+A PILEAFGNAKT++NDNSSRFGK+I
Sbjct: 176 AAISGQ-----------------HSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYID 218
Query: 276 INFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHY 335
I+F+ G I GA IE YLLEKSR RQA DE ++H+FY +L G E K L L S Y
Sbjct: 219 IHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDY 278
Query: 336 RFLTNGPS-SSPGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRE-- 391
+L G + G+ + + + +++VL F+ E + ++++A+L GN+ +
Sbjct: 279 NYLAMGNCITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTF 338
Query: 392 RNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEAL 451
N D + + + LL + D L + + + V ++EQA +A
Sbjct: 339 ENLDACEVLFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAF 398
Query: 452 AKATYERLFRWLVLRLNRALDRSPRQGAS----FLGILDIAGFEIFQLNSFEQLCINYTN 507
K Y RLF W+V ++N A+ + P Q +G+LDI GFE F +NSFEQLCIN+ N
Sbjct: 399 VKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFAN 458
Query: 508 EKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECW 567
E LQQ F +F LEQEEY E I W ++F D Q +D+I P +++L+DEE
Sbjct: 459 EHLQQFFVRHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIAN--KPMNIISLIDEESK 515
Query: 568 FPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLN 627
FPK TD + + K+ + + + P++ + F + H+AG V Y+ +L KN D L+
Sbjct: 516 FPKGTDTTMLHKLNSQHKLNANYIPPKN-NHETQFGINHFAGIVYYETQGFLEKNRDTLH 574
Query: 628 DNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 687
++ L+H S ++ +I++ D G R+ T+ +K SL
Sbjct: 575 GDIIQLVHSSRNKFIKQIFQ--------------ADVAMGAETRKRS-PTLSSQFKRSLE 619
Query: 688 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 747
LM TL P FVRCI PN K+ + L + QLR +G++E IRI R G+P R F
Sbjct: 620 LLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFV 679
Query: 748 EFRQRYEILTPNAIPKGFM-DGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEE 806
EF +RY +L P P D + C++M +A+ + +++G++KIF + LE E
Sbjct: 680 EFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVE 739
Query: 807 RDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKV 866
RD +TD ++ Q RG+ R F K + AA L RHW+ K
Sbjct: 740 RDKAITDRVILLQKVIRGFKDRSNFLKLKN------------AATLIQRHWRGHNC-RKN 786
Query: 867 KPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAE 926
L+++ R Q L + ++L QQ + A+ R A + R A
Sbjct: 787 YGLMRLGF------LRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAV 840
Query: 927 LCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEA 986
L +A RG +A R + L A E + E+++L++ + +A EA
Sbjct: 841 LTVQAY-ARGMIARRLHQ------RLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEA 893
Query: 987 EEGARQKL-QLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1045
E +++L QL + E ++K+ KE + L E +A E
Sbjct: 894 ERKHQERLAQLAREDAERELKE----------------KEAARRKKELLEQMERARHEPV 937
Query: 1046 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1105
+ + T + + + G ++LE+ +R + E + + ++ + E+
Sbjct: 938 NHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDE--ED 995
Query: 1106 LRAQLGRK---------------EEELQAALARAEDEGGARAQL---------LKSLREA 1141
L K L+ L +DEG A L + L E
Sbjct: 996 LSEYKFAKFAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEP 1055
Query: 1142 Q--AALAEAQEDLE-SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKRE 1198
+ A+++ E + ++ T +K + EL+AL+GE E L + +R K
Sbjct: 1056 KYHTAMSDGSEKIPVMTKIYETLGKKTYK---RELQALQGEGEAQLPEGQKKSSVRHKLV 1112
Query: 1199 QEVTELKKTLEEET--RIHE 1216
+ K L EE R+H+
Sbjct: 1113 HLTLKKKSKLTEEVTKRLHD 1132
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,824,592
Number of Sequences: 37866
Number of extensions: 3490711
Number of successful extensions: 78194
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 774
Number of HSP's successfully gapped in prelim test: 1665
Number of HSP's that attempted gapping in prelim test: 19025
Number of HSP's gapped (non-prelim): 18807
length of query: 2003
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1886
effective length of database: 13,817,196
effective search space: 26059231656
effective search space used: 26059231656
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.