BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] (1995 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 3834 0.0 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 3827 0.0 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 3810 0.0 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 2612 0.0 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 2539 0.0 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 2464 0.0 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 2459 0.0 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 2457 0.0 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 2452 0.0 gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 1318 0.0 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1306 0.0 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 1306 0.0 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 1303 0.0 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 1301 0.0 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 1300 0.0 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 1300 0.0 gi|156104908 myosin heavy chain 6 [Homo sapiens] 1295 0.0 gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 1285 0.0 gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 1262 0.0 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 1155 0.0 gi|122937345 myosin VB [Homo sapiens] 558 e-158 gi|153945715 myosin VC [Homo sapiens] 550 e-156 gi|215982794 myosin VA isoform 2 [Homo sapiens] 545 e-154 gi|215982791 myosin VA isoform 1 [Homo sapiens] 542 e-153 gi|28416946 myosin 18A isoform a [Homo sapiens] 536 e-152 gi|42794779 myosin 18A isoform b [Homo sapiens] 531 e-150 gi|154354979 myosin X [Homo sapiens] 478 e-134 gi|118402590 myosin XV [Homo sapiens] 460 e-129 gi|122937512 myosin VIIB [Homo sapiens] 459 e-129 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 456 e-127 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 3834 bits (9943), Expect = 0.0 Identities = 1995/1995 (100%), Positives = 1995/1995 (100%) Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60 Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120 Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180 Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQ 240 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQ Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQ 240 Query: 241 ANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECS 300 ANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECS Sbjct: 241 ANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECS 300 Query: 301 FHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHE 360 FHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHE Sbjct: 301 FHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESLRVLGFSHE 360 Query: 361 EIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRI 420 EIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRI Sbjct: 361 EIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRI 420 Query: 421 KVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIA 480 KVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIA Sbjct: 421 KVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIA 480 Query: 481 GFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDL 540 GFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDL Sbjct: 481 GFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDL 540 Query: 541 IERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYA 600 IERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYA Sbjct: 541 IERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYA 600 Query: 601 GKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGG 660 GKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGG Sbjct: 601 GKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGG 660 Query: 661 RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNG 720 RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNG Sbjct: 661 RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNG 720 Query: 721 VLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRV 780 VLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRV Sbjct: 721 VLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRV 780 Query: 781 GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC 840 GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC Sbjct: 781 GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC 840 Query: 841 AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA 900 AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA Sbjct: 841 AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA 900 Query: 901 QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT 960 QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT Sbjct: 901 QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT 960 Query: 961 EKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1020 EKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL Sbjct: 961 EKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1020 Query: 1021 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE 1080 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE Sbjct: 1021 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE 1080 Query: 1081 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1140 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA Sbjct: 1081 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1140 Query: 1141 QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL 1200 QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL Sbjct: 1141 QEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTL 1200 Query: 1201 EEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL 1260 EEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL Sbjct: 1201 EEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL 1260 Query: 1261 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1320 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT Sbjct: 1261 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1320 Query: 1321 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1380 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG Sbjct: 1321 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1380 Query: 1381 RELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR 1440 RELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR Sbjct: 1381 RELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRR 1440 Query: 1441 RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA 1500 RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA Sbjct: 1441 RLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREA 1500 Query: 1501 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1560 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND Sbjct: 1501 RALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAND 1560 Query: 1561 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 1620 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV Sbjct: 1561 LRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEV 1620 Query: 1621 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE 1680 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE Sbjct: 1621 ERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEE 1680 Query: 1681 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1740 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS Sbjct: 1681 TRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLS 1740 Query: 1741 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA 1800 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA Sbjct: 1741 KAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKA 1800 Query: 1801 ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860 ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL Sbjct: 1801 ESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860 Query: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL Sbjct: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920 Query: 1921 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1980 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS Sbjct: 1921 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1980 Query: 1981 GPSPEPEGSPPAHPQ 1995 GPSPEPEGSPPAHPQ Sbjct: 1981 GPSPEPEGSPPAHPQ 1995 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 3827 bits (9924), Expect = 0.0 Identities = 1995/2003 (99%), Positives = 1995/2003 (99%), Gaps = 8/2003 (0%) Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60 Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120 Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180 Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G 232 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP G Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240 Query: 233 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI Sbjct: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300 Query: 293 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 352 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL Sbjct: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360 Query: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS Sbjct: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420 Query: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 472 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS Sbjct: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480 Query: 473 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 532 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL Sbjct: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540 Query: 533 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 592 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA Sbjct: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600 Query: 593 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS 652 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS Sbjct: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSS 660 Query: 653 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 712 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV Sbjct: 661 LGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLV 720 Query: 713 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 772 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE Sbjct: 721 LDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQACEKMIQALE 780 Query: 773 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA 832 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA Sbjct: 781 LDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSA 840 Query: 833 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 892 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV Sbjct: 841 LRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREV 900 Query: 893 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 952 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE Sbjct: 901 GELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEE 960 Query: 953 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1012 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS Sbjct: 961 ECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNS 1020 Query: 1013 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1072 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK Sbjct: 1021 KLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK 1080 Query: 1073 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1132 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE Sbjct: 1081 LKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLRE 1140 Query: 1133 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1192 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE Sbjct: 1141 AQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQE 1200 Query: 1193 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1252 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE Sbjct: 1201 VTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSE 1260 Query: 1253 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1312 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA Sbjct: 1261 LRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGA 1320 Query: 1313 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1372 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE Sbjct: 1321 LNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE 1380 Query: 1373 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1432 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV Sbjct: 1381 AAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV 1440 Query: 1433 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1492 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE Sbjct: 1441 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1500 Query: 1493 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR 1552 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR Sbjct: 1501 AEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACR 1560 Query: 1553 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1612 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA Sbjct: 1561 VAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLA 1620 Query: 1613 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1672 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK Sbjct: 1621 KQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1680 Query: 1673 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1732 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD Sbjct: 1681 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAD 1740 Query: 1733 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1792 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA Sbjct: 1741 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800 Query: 1793 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1852 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR Sbjct: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1860 Query: 1853 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1912 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR Sbjct: 1861 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1920 Query: 1913 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1972 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE Sbjct: 1921 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1980 Query: 1973 AEEAQPGSGPSPEPEGSPPAHPQ 1995 AEEAQPGSGPSPEPEGSPPAHPQ Sbjct: 1981 AEEAQPGSGPSPEPEGSPPAHPQ 2003 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 3810 bits (9880), Expect = 0.0 Identities = 1995/2036 (97%), Positives = 1995/2036 (97%), Gaps = 41/2036 (2%) Query: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS Sbjct: 1 MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGTSPQVEWTARRLVWVPS 60 Query: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS Sbjct: 61 ELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEAS 120 Query: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG Sbjct: 121 VLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEG 180 Query: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP--------G 232 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVP G Sbjct: 181 AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYG 240 Query: 233 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI Sbjct: 241 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 300 Query: 293 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 352 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL Sbjct: 301 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQERELFQETLESL 360 Query: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS Sbjct: 361 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 420 Query: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 472 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS Sbjct: 421 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGAS 480 Query: 473 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 532 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL Sbjct: 481 FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL 540 Query: 533 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 592 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA Sbjct: 541 DLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQA 600 Query: 593 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD------------ 640 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD Sbjct: 601 DFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFLG 660 Query: 641 ---------------------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 679 VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS Sbjct: 661 SFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLS 720 Query: 680 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 739 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ Sbjct: 721 RLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQ 780 Query: 740 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 799 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER Sbjct: 781 EFRQRYEILTPNAIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEER 840 Query: 800 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 859 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK Sbjct: 841 DLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVK 900 Query: 860 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 919 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL Sbjct: 901 PLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 960 Query: 920 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 979 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE Sbjct: 961 CAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE 1020 Query: 980 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1039 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV Sbjct: 1021 EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKV 1080 Query: 1040 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1099 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR Sbjct: 1081 KSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELR 1140 Query: 1100 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1159 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR Sbjct: 1141 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1200 Query: 1160 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1219 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG Sbjct: 1201 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHG 1260 Query: 1220 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1279 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ Sbjct: 1261 QALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ 1320 Query: 1280 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1339 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE Sbjct: 1321 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1380 Query: 1340 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1399 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE Sbjct: 1381 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1440 Query: 1400 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1459 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL Sbjct: 1441 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1500 Query: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560 Query: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1579 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK Sbjct: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAK 1620 Query: 1580 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1639 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL Sbjct: 1621 LRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKL 1680 Query: 1640 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1699 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL Sbjct: 1681 EGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRL 1740 Query: 1700 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1759 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE Sbjct: 1741 KGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLE 1800 Query: 1760 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1819 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG Sbjct: 1801 EELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLG 1860 Query: 1820 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1879 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER Sbjct: 1861 EEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920 Query: 1880 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1939 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT Sbjct: 1921 RVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVT 1980 Query: 1940 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 1995 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ Sbjct: 1981 TLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQPGSGPSPEPEGSPPAHPQ 2036 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 2612 bits (6770), Expect = 0.0 Identities = 1312/1948 (67%), Positives = 1622/1948 (83%), Gaps = 7/1948 (0%) Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106 Q +WTA++LVW+PSE HGFEAA++++E +E VELAE+G++ + +D IQ+MNPPKFSK Sbjct: 27 QADWTAKKLVWIPSERHGFEAASIKEERGDEVMVELAENGKKAMVNKDDIQKMNPPKFSK 86 Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166 EDMAELTCLNEASVLHNL++RYYSGLIYTYSGLFCVVINPYK LPIY+E I+EMYRGKK Sbjct: 87 VEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIEMYRGKK 146 Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226 RHE+PPH+YA++E AYR MLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASS KGRK Sbjct: 147 RHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKGRK 206 Query: 227 EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286 + +PGELERQLLQANPILE+FGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL Sbjct: 207 DHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266 Query: 287 EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELF 345 EKSRA+RQAKDE +FHIFYQLL GAGE LK+DLLLE ++YRFL+NG PGQ+ ++ F Sbjct: 267 EKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQQDKDNF 326 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 QET+E++ ++GFSHEEI+SML++VS+VLQFGNI+ K+ERNTDQA+MP+NT AQKLC LLG Sbjct: 327 QETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASMPENTVAQKLCHLLG 386 Query: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465 + V +F+RA+LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYERLFRWLV R+N+ALDR Sbjct: 387 MNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEALAKATYERLFRWLVHRINKALDR 446 Query: 466 SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525 + RQGASF+GILDIAGFEIF+LNSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W Sbjct: 447 TKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 526 TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585 F+DFGLDLQPCIDLIERPANPPG+LALLDEECWFPKATDK+FVEK+ QEQG H KFQ+P Sbjct: 507 NFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFVEKLVQEQGSHSKFQKP 566 Query: 586 RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645 R L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDNVA LLHQS+DR AE+WKDV+ IV Sbjct: 567 RQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKDVDRIV 626 Query: 646 GLEQVSSLGDGPPGG--RPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703 GL+QV+ + + G + ++GMFRTVGQLYKESL++LMATL NTNP+FVRCI+PNHEKR Sbjct: 627 GLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKR 686 Query: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763 AGKL+P LVLDQLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEILTPNAIPKGFMDGKQA Sbjct: 687 AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQA 746 Query: 764 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823 CE+MI+ALELDPNLYR+GQSKIFFRAGVLA LEEERDLK+TDII+ FQA RGYLAR+AF Sbjct: 747 CERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAF 806 Query: 824 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883 K+QQQ SAL+V+QRNCAAYLKLRHWQWWR+FTKVKPLLQVTRQ+E LQA+ +EL KV+E Sbjct: 807 AKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKE 866 Query: 884 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943 Q + E+ E++ + QL EE+ LAEQL+AE EL AEAEE R RLAA+KQELE ++ + Sbjct: 867 KQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHD 926 Query: 944 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003 LE+RV EEEE ++ +Q EKK++Q HIQ+LE L+ EEGARQKLQLEKVT EAK+KK EE+ Sbjct: 927 LESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEE 986 Query: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063 +LLLEDQNSK KE+KL+EDR+AE SSQ AEEEEK K+L K+R K E I+D+E+RL+KE Sbjct: 987 ILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKE 1046 Query: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 EK RQELEK KR+LDGE+++LQ+Q+ E Q + +EL+ QL +KEEELQ ALAR +DE + Sbjct: 1047 EKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHK 1106 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183 LK +RE QA +AE QED ESE+ +R KAEKQ+RDL EELEAL+ ELEDTLD+T AQQ Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166 Query: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 ELR+KREQEV ELKK LEEET+ HEA +Q++RQRH AL EL+EQLEQA+R K EK + Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 LE + EL E+ LQ + E E +R++L+ Q+QE+ + +G+R R E AEK + Q Sbjct: 1227 QGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQ 1286 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 EL+NVS L EAE K I+ +K+ +S E+QL D QELLQEETR KL L SR+R +E E Sbjct: 1287 NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKN 1346 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423 L+EQ EEE AR+ +++ Q+QL++ +++ +++ G +E+ EEA+++ ++AEAL+Q Sbjct: 1347 SLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQ 1406 Query: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483 RL EK D+LE+ + RLQQELDD T+DL+ QRQ+ S LEKKQ+KFDQLLAEEK+ R Sbjct: 1407 RLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISAR 1466 Query: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543 EER+RAEAE RE+E +ALSL RALEE EA+EE ERQN+ LRA++E L+SSKDDVGK+ Sbjct: 1467 YAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN 1526 Query: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603 VHELE++ R EQ ++R Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQ RDE Sbjct: 1527 VHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQ 1586 Query: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663 EE++R L KQ+R+ E E ++ERKQR LAVA++KK+E +L++L+AQ+ +A + ++E +KQ Sbjct: 1587 NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQ 1646 Query: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723 LRK+QAQMK+ RE+EE R SR+EIF+Q++ESEK+LK LEAE+L+LQEELA+S+RARR A Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706 Query: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783 +Q+RDE+ADE+ N K+A+L+EKR+LE R+ QLEEELEEEQSN ELLNDR+RK LQV Sbjct: 1707 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766 Query: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843 ++L EL+AERS + K+++ RQQLERQ +EL+ +L E + +++ K TI+ALE+K+ Q Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826 Query: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903 EEQLEQE +ER + KLVRR EK+LKE+ +QVE+ERR ADQ ++Q+EK N R+KQLKRQL Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886 Query: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRR-GPLTF-TTRTVRQVF 1961 EEAEEEA+RA A RR+LQREL+D TE+ E ++REV+TL+NRLRR GP++F ++R+ R+ Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQL 1946 Query: 1962 RLEEG--VASDEEAEEAQPGSGPSPEPE 1987 LE SD++ E + P+ Sbjct: 1947 HLEGASLELSDDDTESKTSDVNETQPPQ 1974 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 2539 bits (6580), Expect = 0.0 Identities = 1267/1941 (65%), Positives = 1589/1941 (81%), Gaps = 8/1941 (0%) Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106 Q +W A++LVWVPS+ GFE A+L++E EEA VEL E+G+++++ +D IQ+MNPPKFSK Sbjct: 23 QADWAAKKLVWVPSDKSGFEPASLKEEVGEEAIVELVENGKKVKVNKDDIQKMNPPKFSK 82 Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166 EDMAELTCLNEASVLHNL+ERYYSGLIYTYSGLFCVVINPYK LPIY+E IVEMY+GKK Sbjct: 83 VEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKK 142 Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226 RHE+PPH+YA+T+ AYRSM+QDREDQSILCTGESGAGKTENTKKVIQYLA+VASS K +K Sbjct: 143 RHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKK 202 Query: 227 EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286 + G ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL Sbjct: 203 DQG---ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLL 259 Query: 287 EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQE-RELF 345 EKSRAIRQAK+E +FHIFY LL GAGE LK DLLLEP + YRFL+NG + PGQ+ +++F Sbjct: 260 EKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDKDMF 319 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 QET+E++R++G EE + +LR++S VLQ GNI K+ERNTDQA+MPDNTAAQK+ LLG Sbjct: 320 QETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMPDNTAAQKVSHLLG 379 Query: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465 + VTDF+R +LTPRIKVGRDYVQKAQTKEQADFA+EALAKATYER+FRWLVLR+N+ALD+ Sbjct: 380 INVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEALAKATYERMFRWLVLRINKALDK 439 Query: 466 SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525 + RQGASF+GILDIAGFEIF LNSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W Sbjct: 440 TKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 499 Query: 526 TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585 F+DFGLDLQPCIDLIE+PA PPG+LALLDEECWFPKATDKSFVEKV QEQG HPKFQ+P Sbjct: 500 NFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQEQGTHPKFQKP 559 Query: 586 RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645 + L+D+ADF ++HYAGKVDYKA+EWLMKNMDPLNDN+A LLHQS+D+ +E+WKDV+ I+ Sbjct: 560 KQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKDVDRII 619 Query: 646 GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703 GL+QV+ + + P + R+GMFRTVGQLYKE L++LMATL NTNP+FVRCI+PNHEK+ Sbjct: 620 GLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKK 679 Query: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763 AGKL+P LVLDQLRCNGVLEGIRICRQGFPNR++FQEFRQRYEILTPN+IPKGFMDGKQA Sbjct: 680 AGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQA 739 Query: 764 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823 C MI+ALELD NLYR+GQSK+FFRAGVLA LEEERDLK+TD+I+ FQA RGYLAR+AF Sbjct: 740 CVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLARKAF 799 Query: 824 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883 KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQV+RQ+E + A+ +EL KV+E Sbjct: 800 AKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVRE 859 Query: 884 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943 Q + + E++ +QL E+ +L EQL+AE ELCAEAEE R RL A+KQELE + + Sbjct: 860 KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHD 919 Query: 944 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003 LEARV EEEE + +Q EKK++QQ+IQELE LE EE ARQKLQLEKVTTEAK+KK EE+ Sbjct: 920 LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979 Query: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063 ++LEDQN KL+KE+KLLEDR+AEF++ EEEEK KSL KL+ K+EA I D+E+RLR+E Sbjct: 980 QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039 Query: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 EK RQELEK +R+L+G+S++L +Q+ E Q + EL+ QL +KEEELQAALAR E+E + Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183 LK +RE ++ ++E QEDLESER +R KAEKQ+RDLGEELEAL+ ELEDTLDST AQQ Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159 Query: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 ELRSKREQEV LKKTLEEE + HEA +QE+RQ+H QA+ ELAEQLEQ +R K EK + Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 LE E EL E+ L + + E +R+++E QLQE+Q + +GER R E A+K+ + Q Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQ 1279 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 EL+NV+G L++++SK+ +L+K+ S+ E+QL D QELLQEE R KL+L ++++ +E E Sbjct: 1280 VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423 REQLEEE A+ +++ T AQ+++ +++ E+ G LE EE +R+ ++ E L+Q Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQ 1399 Query: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483 R EK D+LE+ + RLQQELDD +DL+ QRQ LEKKQ+KFDQLLAEEK + Sbjct: 1400 RHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAK 1459 Query: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543 EER+RAEAE RE+E +ALSL RALEE E + ELER N+ R E+E L+SSKDDVGKS Sbjct: 1460 YAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519 Query: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603 VHELE++ R EQ +++ Q+ ELEDEL A EDAKLRLEV +QA+K Q ERDLQGRDE Sbjct: 1520 VHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ 1579 Query: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663 EE+++QL +Q+R+ E E ++ERKQR++AVAARKKLE +L++L+A + SA + ++EA+KQ Sbjct: 1580 SEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQ 1639 Query: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723 LRK+QAQMK+ RE+++TR SREEI +Q +E+EK+LK +EAE+++LQEELAA++RA+RQA Sbjct: 1640 LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA 1699 Query: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783 QQ+RDE+ADE+AN + A LEEKR+LE R+ QLEEELEEEQ N+EL+NDR +K LQ+ Sbjct: 1700 QQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759 Query: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843 + + T+L+ ERS + K E+ RQQLERQ +EL+ +L E + ++++K +I ALE+K+AQ Sbjct: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819 Query: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903 EEQL+ ET+ER + K VRR EK+LK+V+LQV++ERR A+Q +DQ +K + R+KQLKRQL Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879 Query: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRL 1963 EEAEEEA RA A RR+LQRELED TE+A++MNREV++L+N+LRRG L F R++ R Sbjct: 1880 EEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFV--VPRRMARK 1937 Query: 1964 EEGVASDEEAEEAQPGSGPSP 1984 G SDEE + G+ P Sbjct: 1938 GAGDGSDEEVDGKADGAEAKP 1958 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 2464 bits (6387), Expect = 0.0 Identities = 1234/1933 (63%), Positives = 1573/1933 (81%), Gaps = 5/1933 (0%) Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106 Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86 Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166 EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146 Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226 RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206 Query: 227 EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286 + + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266 Query: 287 EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELF 345 EKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P Q+ E+F Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMF 326 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 QET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAAQK+C L+G Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386 Query: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465 + VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ R+N+ALD+ Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446 Query: 466 SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525 + RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 526 TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585 F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG HPKFQ+P Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKP 566 Query: 586 RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645 + L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++WKDV+ IV Sbjct: 567 KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626 Query: 646 GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703 GL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR Sbjct: 627 GLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKR 686 Query: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763 +GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQA Sbjct: 687 SGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQA 746 Query: 764 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823 C MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF Sbjct: 747 CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAF 806 Query: 824 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883 KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E Sbjct: 807 AKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKE 866 Query: 884 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943 QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E Sbjct: 867 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926 Query: 944 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003 +EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E++ Sbjct: 927 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986 Query: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063 +L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KE Sbjct: 987 ILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046 Query: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 EK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + Sbjct: 1047 EKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183 LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQ Sbjct: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1166 Query: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 ELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + Sbjct: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++R +E E Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423 L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R +E E LTQ Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406 Query: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483 + EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466 Query: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543 +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+ Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526 Query: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603 VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586 Query: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663 EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQ Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646 Query: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723 LRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706 Query: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783 +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766 Query: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843 E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826 Query: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903 EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQL Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886 Query: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFR- 1962 EEAEEE+ R A RR+LQREL++ TES E+M REV L+++LRRG T + R R Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRR 1946 Query: 1963 -LEEGVASDEEAE 1974 +E S+EE + Sbjct: 1947 VIENADGSEEETD 1959 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 2459 bits (6374), Expect = 0.0 Identities = 1226/1906 (64%), Positives = 1561/1906 (81%), Gaps = 3/1906 (0%) Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106 Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86 Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166 EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146 Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226 RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206 Query: 227 EPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLL 286 + + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGANIETYLL Sbjct: 207 DTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLL 266 Query: 287 EKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELF 345 EKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P Q+ E+F Sbjct: 267 EKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAAQDDEMF 326 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 QET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAAQK+C L+G Sbjct: 327 QETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMG 386 Query: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDR 465 + VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ R+N+ALD+ Sbjct: 387 INVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDK 446 Query: 466 SPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPW 525 + RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEEYQREGI W Sbjct: 447 THRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEW 506 Query: 526 TFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRP 585 F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG HPKFQ+P Sbjct: 507 NFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKP 566 Query: 586 RHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645 + L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++WKDV+ IV Sbjct: 567 KQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIV 626 Query: 646 GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703 GL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRCI+PNHEKR Sbjct: 627 GLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKR 686 Query: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763 +GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPKGFMDGKQA Sbjct: 687 SGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKGFMDGKQA 746 Query: 764 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823 C MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA RGYLAR+AF Sbjct: 747 CILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAF 806 Query: 824 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883 KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ ELQK +E Sbjct: 807 AKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKE 866 Query: 884 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943 QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQELE ++ E Sbjct: 867 RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHE 926 Query: 944 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003 +EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EAK+KK E++ Sbjct: 927 MEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDE 986 Query: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063 +L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I+++E RL+KE Sbjct: 987 ILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKE 1046 Query: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 EK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR +DE + Sbjct: 1047 EKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK 1106 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183 LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDTLDST QQ Sbjct: 1107 NNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQ 1166 Query: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 ELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R K +K + Sbjct: 1167 ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE +K+ + Q Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++R +E E Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423 L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R +E E LTQ Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406 Query: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483 + EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLAEEK + Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466 Query: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543 +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+SSKDDVGK+ Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526 Query: 1544 VHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEA 1603 VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ERDLQ RDE Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586 Query: 1604 GEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQ 1663 EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +G+EEA+KQ Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646 Query: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQA 1723 LRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA++RAR+QA Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706 Query: 1724 QQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQV 1783 +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR RK Q Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766 Query: 1784 ESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQA 1843 E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAALE+K+AQ Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826 Query: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903 EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN RVKQLKRQL Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886 Query: 1904 EEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1949 EEAEEE+ R A RR+LQREL++ TES E+M REV L+++LR P Sbjct: 1887 EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1932 Score = 196 bits (499), Expect = 1e-49 Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%) Query: 1101 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1153 Q+ R+EEE+QA L + ++ LK L + + L E QE L++E + Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905 Query: 1154 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1206 AE+ R ++L E L + LE+ D Q R K Q++ +L++ LEEE Sbjct: 906 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 962 Query: 1207 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1263 EAA Q+L+ A + +L +++ K R LE +S+L L+ + Sbjct: 963 -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1021 Query: 1264 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1323 + + + + E + E++ R E++R E + ++ + + + + + +++ L Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1081 Query: 1324 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1383 +L+ E +L A L +E K ++R +E + L+E L+ E AAR +A ++ Sbjct: 1082 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1141 Query: 1384 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1442 + +L + E+ + +E R + +E L + L E+T + + +++ R++ Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1201 Query: 1443 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1502 Q +++ T LEQ ++ + L+K ++ ++ A+ + + ++ E + ++ EA+ Sbjct: 1202 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1261 Query: 1503 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1561 L + + AR EL + L+ E+E++ ++ GK++ + A D+ Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1310 Query: 1562 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1619 + ++L+D + E+ + +L V+ + + + ER+ LQ + + E ++ L + + Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370 Query: 1620 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1672 ++ D ++K + A +K+ + E+E L Q ++ K ++Q ++ Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430 Query: 1673 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1731 +L +++ R ++ S + +++ L AE + + A DRA +A++ ++ A Sbjct: 1431 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1485 Query: 1732 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1784 +A L +A LE K +LE L+ E+E+ S N L R L Q+E Sbjct: 1486 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542 Query: 1785 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1843 + T+L E + +LE +Q L+G+ E D AR +++ L+ +L + Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1601 Query: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903 E +LE E ++R L+ ++ E LK++ LQ + + ++ QL K ++K +R+L Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1661 Query: 1904 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1949 E+A E++A +A +LQ +L + + + E L L Sbjct: 1662 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1720 Query: 1950 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1980 L+ + RLE +A EE E + G+ Sbjct: 1721 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1751 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 2457 bits (6369), Expect = 0.0 Identities = 1234/1940 (63%), Positives = 1573/1940 (81%), Gaps = 12/1940 (0%) Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106 Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86 Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166 EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146 Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226 RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206 Query: 227 EPGVP-------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 279 + + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGA Sbjct: 207 DTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 266 Query: 280 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG 339 NIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P Sbjct: 267 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPA 326 Query: 340 -QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQ 398 Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAAQ Sbjct: 327 AQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQ 386 Query: 399 KLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLR 458 K+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ R Sbjct: 387 KVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTR 446 Query: 459 LNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 518 +N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEEY Sbjct: 447 VNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 506 Query: 519 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG 578 QREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG Sbjct: 507 QREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGS 566 Query: 579 HPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIW 638 HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++W Sbjct: 567 HPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626 Query: 639 KDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 696 KDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRCI Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686 Query: 697 VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 756 +PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPKG Sbjct: 687 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746 Query: 757 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 816 FMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA RG Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806 Query: 817 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 876 YLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866 Query: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 936 ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQE Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926 Query: 937 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 996 LE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EAK Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986 Query: 997 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1056 +KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I+++ Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046 Query: 1057 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1116 E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106 Query: 1117 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1176 +DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDTL Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166 Query: 1177 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1236 DST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R K Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226 Query: 1237 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1296 +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286 Query: 1297 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356 +K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++R Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346 Query: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1416 +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R + Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406 Query: 1417 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1476 E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLAE Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466 Query: 1477 EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSS 1536 EK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+SS Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1526 Query: 1537 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 1596 KDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ERD Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586 Query: 1597 LQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1656 LQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +G Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646 Query: 1657 KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS 1716 +EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA+ Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706 Query: 1717 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1776 +RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766 Query: 1777 RKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAAL 1836 RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAAL Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826 Query: 1837 ESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRV 1896 E+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN RV Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1886 Query: 1897 KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRT 1956 KQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LRRG T + Sbjct: 1887 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPS 1946 Query: 1957 VRQVFR--LEEGVASDEEAE 1974 R R +E S+EE + Sbjct: 1947 RRSGGRRVIENADGSEEETD 1966 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 2452 bits (6356), Expect = 0.0 Identities = 1226/1913 (64%), Positives = 1561/1913 (81%), Gaps = 10/1913 (0%) Query: 47 QVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSK 106 Q +W A+RLVWVPSE GFEAA++++E +E VEL E+G+++ + +D IQ+MNPPKFSK Sbjct: 27 QADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSK 86 Query: 107 AEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK 166 EDMAELTCLNEASVLHNLRERY+SGLIYTYSGLFCVV+NPYK LPIY+E IV+MY+GKK Sbjct: 87 VEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK 146 Query: 167 RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRK 226 RHE+PPH+YA+ + AYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLA VASS KG+K Sbjct: 147 RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK 206 Query: 227 EPGVP-------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGA 279 + + GELE+QLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDV GYIVGA Sbjct: 207 DTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 266 Query: 280 NIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG 339 NIETYLLEKSRAIRQA+DE +FHIFY ++ GA E++++DLLLE ++Y FL+NG P Sbjct: 267 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPA 326 Query: 340 -QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQ 398 Q+ E+FQET+E++ ++GFS EE +S+L++VS+VLQ GNI K+ERNTDQA+MPDNTAAQ Sbjct: 327 AQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQ 386 Query: 399 KLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLR 458 K+C L+G+ VTDF+R++LTPRIKVGRD VQKAQTKEQADFA+EALAKATYERLFRW++ R Sbjct: 387 KVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTR 446 Query: 459 LNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 518 +N+ALD++ RQGASFLGILDIAGFEIF++NSFEQLCINYTNEKLQQLFNHTMF+LEQEEY Sbjct: 447 VNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 506 Query: 519 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG 578 QREGI W F+DFGLDLQPCI+LIERP NPPG+LALLDEECWFPKATDKSFVEK+ EQG Sbjct: 507 QREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGS 566 Query: 579 HPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIW 638 HPKFQ+P+ L+D+ +FS++HYAGKVDY A+ WL KNMDPLNDNV +LL+ S+D+ A++W Sbjct: 567 HPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLW 626 Query: 639 KDVEGIVGLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCI 696 KDV+ IVGL+Q++ + + P + ++GMFRTVGQLYKE L +LM TL NT P+FVRCI Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686 Query: 697 VPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG 756 +PNHEKR+GKL+ LVL+QLRCNGVLEGIRICRQGFPNRI+FQEFRQRYEIL NAIPKG Sbjct: 687 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746 Query: 757 FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARG 816 FMDGKQAC MI+ALELDPNLYR+GQSKIFFR GVLA LEEERDLK+TD+I++FQA RG Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806 Query: 817 YLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQ 876 YLAR+AF KRQQQ +A++V+QRNCAAYLKLR+WQWWRLFTKVKPLLQVTRQ+E +QA+ Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKED 866 Query: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE 936 ELQK +E QQ++ E+ EL+ + +QL EE+ L EQL+AE EL AEAEE R RLAA+KQE Sbjct: 867 ELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926 Query: 937 LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAK 996 LE ++ E+EAR+ EEE+ +Q+Q E+K++ Q + +LE LE EE ARQKLQLEKVT EAK Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAK 986 Query: 997 MKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADM 1056 +KK E+++L+++DQN+KLSKERKLLE+R+++ ++ AEEEEK K+L KL+ K+E+ I+++ Sbjct: 987 IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046 Query: 1057 EDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARA 1116 E RL+KEEK RQELEKLKR+L+G++S+ EQ+ + Q + EL+ QL +KEEELQAALAR Sbjct: 1047 EVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARL 1106 Query: 1117 EDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTL 1176 +DE + LK +RE + +++ QEDL+SER AR KAEKQ+RDLGEELEAL+ ELEDTL Sbjct: 1107 DDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTL 1166 Query: 1177 DSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1236 DST QQELR+KREQEVT LKK L+EETR HEA VQE+RQ+H QA+ EL EQLEQ +R K Sbjct: 1167 DSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAK 1226 Query: 1237 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA 1296 +K + LE E ++L EL L A+QE E ++++LE Q+QE+Q + DGERARAE Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286 Query: 1297 EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356 +K+ + Q E+E+V+G LNEAE K I+L+K+++S +QL D QELLQEETR KL + +++R Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346 Query: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1416 +E E L++QL+EE A++ R + T QLS+ +++ ++ A +EA EE ++R + Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406 Query: 1417 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1476 E E LTQ+ EK D+LE+ + RLQQELDD +DL+ QRQLVS LEKKQRKFDQLLAE Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466 Query: 1477 EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSS 1536 EK + +ER+RAEAE RE+E +ALSL RALEE EA+EELER N+ L+AE+E L+SS Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1526 Query: 1537 KDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERD 1596 KDDVGK+VHELE++ R E +++ Q+ ELEDEL A EDAKLRLEV +QALK Q ERD Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586 Query: 1597 LQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1656 LQ RDE EE+RRQL +QL + E E ++ERKQR LA AA+KKLEG+L++L+ Q SA +G Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646 Query: 1657 KEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS 1716 +EEA+KQLRK+QAQMK+ RE+E+ R SR+EIF+ +E+EK+ K LEA++++LQE+LAA+ Sbjct: 1647 REEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA 1706 Query: 1717 DRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1776 +RAR+QA +++E+A+E+A+ + A+ +EKR+LE R+ QLEEELEEEQ N E ++DR Sbjct: 1707 ERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 1766 Query: 1777 RKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAAL 1836 RK Q E L+ EL+ ERS + K ES RQQLERQ +ELR +L E + +++ K TIAAL Sbjct: 1767 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAAL 1826 Query: 1837 ESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRV 1896 E+K+AQ EEQ+EQE RE+ + K +++ +K+LKE++LQVE+ER++A+Q ++Q EKGN RV Sbjct: 1827 EAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARV 1886 Query: 1897 KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1949 KQLKRQLEEAEEE+ R A RR+LQREL++ TES E+M REV L+++LR P Sbjct: 1887 KQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRGPP 1939 Score = 196 bits (499), Expect = 1e-49 Identities = 208/931 (22%), Positives = 424/931 (45%), Gaps = 76/931 (8%) Query: 1101 QLGRKEEELQAA---LARAEDEGGARAQLLKSLREAQAALAEA----QEDLESERVARTK 1153 Q+ R+EEE+QA L + ++ LK L + + L E QE L++E + Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912 Query: 1154 AEKQR-------RDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRI 1206 AE+ R ++L E L + LE+ D Q R K Q++ +L++ LEEE Sbjct: 913 AEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEE--- 969 Query: 1207 HEAAVQELRQRHGQA---LGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1263 EAA Q+L+ A + +L +++ K R LE +S+L L+ + Sbjct: 970 -EAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEK 1028 Query: 1264 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRL 1323 + + + + E + E++ R E++R E + ++ + + + + + +++ L Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAEL 1088 Query: 1324 SKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGREL 1383 +L+ E +L A L +E K ++R +E + L+E L+ E AAR +A ++ Sbjct: 1089 KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQK 1148 Query: 1384 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD-RLERGRRRL 1442 + +L + E+ + +E R + +E L + L E+T + + +++ R++ Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKH 1208 Query: 1443 QQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARA 1502 Q +++ T LEQ ++ + L+K ++ ++ A+ + + ++ E + ++ EA+ Sbjct: 1209 AQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQV 1268 Query: 1503 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDV-GKSVHELERACRVAEQAANDL 1561 L + + AR EL + L+ E+E++ ++ GK++ + A D+ Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI-----------KLAKDV 1317 Query: 1562 RAQVTELED-ELTAAEDAKLRLEVTVQALKTQHERD-LQGRDEAGEERRRQLAKQLRDAE 1619 + ++L+D + E+ + +L V+ + + + ER+ LQ + + E ++ L + + Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377 Query: 1620 VE-RDEERKQRTLAVAA------RKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK 1672 ++ D ++K + A +K+ + E+E L Q ++ K ++Q ++ Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437 Query: 1673 ELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAAS-DRARRQAQQDRDEMA 1731 +L +++ R ++ S + +++ L AE + + A DRA +A++ ++ A Sbjct: 1438 DLVVDLDNQR----QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEARE-KETKA 1492 Query: 1732 DEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS-------NSELLNDRYRKLLLQVE 1784 +A L +A LE K +LE L+ E+E+ S N L R L Q+E Sbjct: 1493 LSLARA-LEEA--LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549 Query: 1785 SLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR-ARHKMTIAALESKLAQA 1843 + T+L E + +LE +Q L+G+ E D AR +++ L+ +L + Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQF-ERDLQARDEQNEEKRRQLQRQLHEY 1608 Query: 1844 EEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQL 1903 E +LE E ++R L+ ++ E LK++ LQ + + ++ QL K ++K +R+L Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQREL 1668 Query: 1904 EEA--------------EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1949 E+A E++A +A +LQ +L + + + E L L Sbjct: 1669 EDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEEL-ASS 1727 Query: 1950 LTFTTRTVRQVFRLEEGVASDEEAEEAQPGS 1980 L+ + RLE +A EE E + G+ Sbjct: 1728 LSGRNALQDEKRRLEARIAQLEEELEEEQGN 1758 >gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo sapiens] Length = 1935 Score = 1318 bits (3411), Expect = 0.0 Identities = 735/1907 (38%), Positives = 1155/1907 (60%), Gaps = 34/1907 (1%) Query: 56 VWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAEL 113 V+VP + F A + R+ G+ AE E G+ + + DQ+ + NPPKF K EDMA L Sbjct: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEY---GKTVTVKEDQVMQQNPPKFDKIEDMAML 93 Query: 114 TCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPH 173 T L+E +VL+NL++RY S +IYTYSGLFCV +NPYK LP+YT +V YRGKKR E PPH Sbjct: 94 TFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPH 153 Query: 174 VYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPGE 233 ++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ K+ PG+ Sbjct: 154 IFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGK 213 Query: 234 --LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRA 291 LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR Sbjct: 214 GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRV 273 Query: 292 IRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETL 349 I Q K E +HIFYQ+L +L LL+ + Y F++ G ++ + E T Sbjct: 274 IFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATD 333 Query: 350 ESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVT 409 + VLGF+ EE SM ++ A++ FGN+ K ++ +QA A K L+GL Sbjct: 334 NAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLMGLNSA 393 Query: 410 DFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPR 468 D + L PR+KVG +YV K Q +Q +A ALAKA YER+F W+V R+N L+ + PR Sbjct: 394 DLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPR 453 Query: 469 QGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFL 528 Q F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+ Sbjct: 454 Q--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFI 511 Query: 529 DFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRH 587 DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G FQ+PR+ Sbjct: 512 DFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRN 568 Query: 588 LRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645 ++ +A FS++HYAG VDY WL KN DPLN+ V L +S+ +L + ++ + G Sbjct: 569 IKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAG-- 626 Query: 646 GLEQVSSLGDGP---PGGRPRRGM-FRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHE 701 D P G+ ++G F+TV L++E+L++LM L +T+P FVRCI+PN Sbjct: 627 --------ADAPIEKGKGKAKKGSSFQTVSALHRENLNKLMTNLRSTHPHFVRCIIPNET 678 Query: 702 KRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDG 760 K G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+G F+D Sbjct: 679 KSPGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPEGQFIDS 738 Query: 761 KQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLAR 820 ++ EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA +RG LAR Sbjct: 739 RKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLAR 798 Query: 821 RAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQK 880 ++K +++ +L V+Q N A++ +++W W +L+ K+KPLL+ +++ + + +E + Sbjct: 799 MEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTR 858 Query: 881 VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940 ++E ++S EL+ ++ L +E+ L Q++AE + A+AEE +L K +LE Sbjct: 859 LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAK 918 Query: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000 V E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K Sbjct: 919 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNL 978 Query: 1001 EEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRL 1060 E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E L Sbjct: 979 TEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSL 1038 Query: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120 +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ EL A AR EDE Sbjct: 1039 EQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQ 1098 Query: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180 +QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+ +T+ Sbjct: 1099 ALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1158 Query: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 Q E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K E Sbjct: 1159 VQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLE 1218 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 K + + E+ ++ + + + A+ E+ R LE Q+ E + +A + +R+ + + Sbjct: 1219 KEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRA 1278 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 + Q E +S L+E E+ +L++ + QL D + L+EE +AK AL +++ Sbjct: 1279 KLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARH 1338 Query: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAE 1419 + LREQ EEE A+ R L A +++++WR + E +A E EEA+++ A+ + Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1398 Query: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479 + + LE+ + RLQ E++D +D+E+ + L+KKQR FD++LAE K Sbjct: 1399 EAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQ 1458 Query: 1480 AVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDD 1539 + E E ++ E R L A EE E E +R+N+ L+ E+ L Sbjct: 1459 KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGS 1518 Query: 1540 VGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQG 1599 GK++HELE+ + E +L++ + E E L E LR ++ +K + ER L Sbjct: 1519 SGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAE 1578 Query: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659 +DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++ A + E Sbjct: 1579 KDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAE 1638 Query: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719 A KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ + ++R+ Sbjct: 1639 AQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERS 1698 Query: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779 R+ A+Q+ E ++ V + +++ +K++++ L QL+ E+EE ++ +K Sbjct: 1699 RKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758 Query: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839 + + EL E+ SA E ++ +E+ I++L+ RL E + A K + LE++ Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEAR 1818 Query: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899 + + E +LE E + S K +R++E+R+KE+ Q EE+R+ +L+D ++K L+VK Sbjct: 1819 VRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAY 1878 Query: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 KRQ EEAEE+A+ + R++Q EL++ E A+ +V LR + R Sbjct: 1879 KRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1925 Score = 226 bits (576), Expect = 2e-58 Identities = 209/959 (21%), Positives = 432/959 (45%), Gaps = 57/959 (5%) Query: 1044 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESS---ELQEQMVEQQQRAEELRA 1100 KL K + + E R ++ ++E +LK L+ + EL+E+MV Q +L+ Sbjct: 831 KLYFKIKPLLKSAE-REKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQL 889 Query: 1101 QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRD 1160 Q+ +++ L A R + QL+K+ + +A + E E LE E + ++R Sbjct: 890 QVQAEQDNLADAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 942 Query: 1161 LGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1217 L +E L+ +++D TL ++ + + +TE L+E + L++ Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002 Query: 1218 HGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQ 1277 H QAL +L + ++ K ++ LE +V +L L + R + E+ +R+LE Sbjct: 1003 HQQALDDLQAEEDKVN----TLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGD 1058 Query: 1278 LQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDA 1337 L+ Q D E + + E+L++ EL ++ + + ++ +L K+L +A++ + Sbjct: 1059 LKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEEL 1118 Query: 1338 QELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ 1397 +E L+ E A+ + + E + E+LEE A + +A+ + RR Sbjct: 1119 EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178 Query: 1398 EEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDAT 1450 EE EA A R+ ++ +AE E +D L+R +++L++E LDD T Sbjct: 1179 EEATLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232 Query: 1451 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LT 1506 ++EQ + + LEK R + + E ++ EE +R+ + + A+ + L+ Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKA----EETQRSVNDLTSQRAKLQTENGELS 1288 Query: 1507 RALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVT 1566 R L+E++ +L R +LE L ++ K+ + L A + A + LR Q Sbjct: 1289 RQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYE 1348 Query: 1567 ELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEER 1626 E + + + V +T++E D R E EE +++LA++L++AE + Sbjct: 1349 EETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVN 1408 Query: 1627 KQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE 1686 + + + +L+ E+E+L + + K+ R + E ++ EE+++ E Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468 Query: 1687 EIFSQNRESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNL 1739 S+K + L E+ +L+ E L R + Q++ ++ +++ + Sbjct: 1469 S-------SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGK 1521 Query: 1740 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1799 + + + ++QLE +L+ LEE +++ E + + L+ + E+ ER + K Sbjct: 1522 TIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEK 1579 Query: 1800 AESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILS 1857 E Q ++ + DA R+R++ +E L + E QL R + Sbjct: 1580 DEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEA 1639 Query: 1858 GKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1917 K V+ + LK+ +Q+++ R D L++ + R L+ +LEE + + R Sbjct: 1640 QKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSR 1699 Query: 1918 RRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 + ++EL + +E + ++ + T+L N+ ++ + ++E ++E+A++A Sbjct: 1700 KLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758 Score = 70.9 bits (172), Expect = 1e-11 Identities = 71/306 (23%), Positives = 139/306 (45%), Gaps = 25/306 (8%) Query: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 933 +L + ++ ++V LQ + L++ + +L + +RA +L A E L A Sbjct: 1628 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684 Query: 934 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 977 +EL VV + E ++ E+E E S ++Q +KK++ + +L+ +E Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEA 1744 Query: 978 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1037 +E + + +K T+A M E+L +D ++ L + +K +E + + + E E+ Sbjct: 1745 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1802 Query: 1038 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1096 +K K K EA + ++E+ L E+K E K R+ + EL Q E ++ Sbjct: 1803 IALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLL 1862 Query: 1097 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1156 L+ + + + +++A +AE+ L R+ Q L EA+E + K Sbjct: 1863 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1922 Query: 1157 QRRDLG 1162 + RD+G Sbjct: 1923 KSRDIG 1928 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 1306 bits (3380), Expect = 0.0 Identities = 722/1907 (37%), Positives = 1151/1907 (60%), Gaps = 21/1907 (1%) Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111 A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171 +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEP--- 228 PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 Query: 229 -GVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287 + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLE Sbjct: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272 Query: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELF 345 KSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S ++E Sbjct: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K L Sbjct: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392 Query: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD- 464 L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+ LD Sbjct: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDT 452 Query: 465 RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524 + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI Sbjct: 453 KQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510 Query: 525 WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQ 583 WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G FQ Sbjct: 511 WTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567 Query: 584 RPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDV 641 +P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A+++ Sbjct: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS-- 625 Query: 642 EGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHE 701 G E + G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN Sbjct: 626 -GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684 Query: 702 KRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDG 760 K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D Sbjct: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744 Query: 761 KQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLAR 820 K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+LAR Sbjct: 745 KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804 Query: 821 RAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQK 880 +Q+ +++ A+ +Q N +++ ++HW W +LF K+KPLL+ ++ + +E QK Sbjct: 805 VEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 864 Query: 881 VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940 +++ +S + EL+ ++ L +E+ L Q++AEAE A+AEE +L K +LE Sbjct: 865 IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK 924 Query: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000 + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K Sbjct: 925 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 984 Query: 1001 EEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRL 1060 E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E L Sbjct: 985 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1044 Query: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120 +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +KE E+ ++ EDE Sbjct: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQ 1104 Query: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180 QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+ Sbjct: 1105 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1164 Query: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K E Sbjct: 1165 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLE 1224 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 K + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R + + Sbjct: 1225 KEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRG 1284 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 R Q E S L+E E+ +LS+ + Q+ + + L+EE +AK AL +++ Sbjct: 1285 RLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344 Query: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAE 1419 + LREQ EEE ++ R L A ++++WR + E +A E EEA+++ A+ + Sbjct: 1345 DCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1404 Query: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479 A + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LAE K Sbjct: 1405 AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQ 1464 Query: 1480 AVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDD 1539 E E ++ E R + A EE + E L+R+N+ L+ E+ L + Sbjct: 1465 KCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524 Query: 1540 VGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQG 1599 GK +HELE+ + EQ +L+A + E E L E LR+++ + +K++ +R + Sbjct: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584 Query: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659 +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + E Sbjct: 1585 KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE 1644 Query: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719 A++ R Q +K+ +++ S+E++ Q E+R L+AE+ L+ L ++R+ Sbjct: 1645 ALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704 Query: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779 R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ +K Sbjct: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 Query: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839 + + EL E+ SA E ++ +E+ +++L+ RL E + A K I LE++ Sbjct: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824 Query: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899 + + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK Sbjct: 1825 VRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 1884 Query: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 KRQ EEAEE+++ A R+LQ ELE+ E A+ +V LR + R Sbjct: 1885 KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 Score = 224 bits (572), Expect = 5e-58 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%) Query: 1067 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 ++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R + Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1180 QL+K+ + +A + E E E E + ++R L +E L+ +++D TL Sbjct: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971 Query: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 ++ + + +TE L+E + L++ H Q L +L + ++ Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+ Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 + + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + + Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 Query: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1420 E + E+LEE A + +A+ + RR EE EA R+ ++ Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205 Query: 1421 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1478 +AE E +D L+R +++L++E + M+++ V T+ K + +++ E++ Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261 Query: 1479 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533 + L++ EE ++ A+ + + +R L+E++ +L R +A ++E L Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321 Query: 1534 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1593 ++ K+ + L A + + + LR Q E ++ + A + V +T++ Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381 Query: 1594 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1653 E D R E EE +++LA++L+ AE + + +++L+ E+E+L + Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441 Query: 1654 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1710 K+ R + E ++ EET E S+K + L E+ +++ Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494 Query: 1711 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1766 ++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE + Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554 Query: 1767 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1826 ++ E + ++ L++ + +E+ +R + K E Q I+ + DA R Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612 Query: 1827 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1884 +R+ +E L + E QL R + + R + LK+ + +++ R + Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 Query: 1885 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1944 L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 Query: 1945 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 ++ + L+E ++E+A++A Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 Score = 191 bits (486), Expect = 5e-48 Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%) Query: 856 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 906 TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE + Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058 Query: 907 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966 +L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118 Query: 967 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1015 I+ELE +EAE +R K + ++ ++++ E L + + + ++ Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178 Query: 1016 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1057 K R+ LE+ + + AA E E++ +L +++ K E I D+ Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238 Query: 1058 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1117 + K + LEK+ R L+ + SEL+ + EQQ+ +L AQ GR + E + + Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298 Query: 1118 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1177 ++ +QL + + + E + LE E A+ + + + LR + E+ + Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358 Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237 S Q SK EV + + E + ++E +++ Q L E +E Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418 Query: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1297 + EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++ Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477 Query: 1298 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356 K R+ EL + A E+ + L +E + + ++ D E + E + L + Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537 Query: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1415 +E E L+ LEE A+ E ++ Q +L++ + + + A E ++ +R Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597 Query: 1416 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1475 R E++ L + + + R +++++ +L++ + L ++ + + R +L Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657 Query: 1476 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1530 + + + A+ +E + + E RA L +EE + E+ ER + EL Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717 Query: 1531 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1574 +L+++K D+ + E+E + A A + +T+ + +EL Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777 Query: 1575 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1626 +D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + E+ Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836 Query: 1627 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1665 K+ AV +K E ++EL +A++ S + EEA +Q Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896 Query: 1666 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712 A+ ++L E+EE + ++++ ++ R+K E + EE Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 1306 bits (3380), Expect = 0.0 Identities = 722/1907 (37%), Positives = 1151/1907 (60%), Gaps = 21/1907 (1%) Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111 A+ V+V F ++ + V+ E G L + DQ+ MNPPK+ K EDMA Sbjct: 34 AKTSVFVAEPKESFVKGTIQSREGGKVTVK-TEGGATLTVKDDQVFPMNPPKYDKIEDMA 92 Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171 +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E P Sbjct: 93 MMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAP 152 Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEP--- 228 PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITS 212 Query: 229 -GVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287 + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLE Sbjct: 213 GKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLE 272 Query: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELF 345 KSR + Q K E S+HIFYQ+ +L LL+ + Y F++ G S ++E Sbjct: 273 KSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEEL 332 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLG 405 T ++ +LGF++EE +S+ ++ AV+ +GN+ K+++ +QA A K L Sbjct: 333 MATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVADKAAYLQS 392 Query: 406 LGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD- 464 L D +AL PR+KVG +YV K QT EQ A+ ALAKA YE++F W+V R+N+ LD Sbjct: 393 LNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDT 452 Query: 465 RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524 + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI Sbjct: 453 KQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510 Query: 525 WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQ 583 WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G FQ Sbjct: 511 WTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQ 567 Query: 584 RPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDV 641 +P+ ++ +A+ F+++HYAG VDY WL KN DPLN+ V L +S + A+++ Sbjct: 568 KPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLFS-- 625 Query: 642 EGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHE 701 G E + G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN Sbjct: 626 -GAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684 Query: 702 KRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDG 760 K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D Sbjct: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDS 744 Query: 761 KQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLAR 820 K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+LAR Sbjct: 745 KKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLAR 804 Query: 821 RAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQK 880 +Q+ +++ A+ +Q N +++ ++HW W +LF K+KPLL+ ++ + +E QK Sbjct: 805 VEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQK 864 Query: 881 VQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940 +++ +S + EL+ ++ L +E+ L Q++AEAE A+AEE +L K +LE Sbjct: 865 IKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAK 924 Query: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKF 1000 + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K Sbjct: 925 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 984 Query: 1001 EEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRL 1060 E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E L Sbjct: 985 TEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSL 1044 Query: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120 +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +KE E+ ++ EDE Sbjct: 1045 EQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQ 1104 Query: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTN 1180 QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+ Sbjct: 1105 ALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATS 1164 Query: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K E Sbjct: 1165 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLE 1224 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 K + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R + + Sbjct: 1225 KEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRG 1284 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 R Q E S L+E E+ +LS+ + Q+ + + L+EE +AK AL +++ Sbjct: 1285 RLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRH 1344 Query: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAE 1419 + LREQ EEE ++ R L A ++++WR + E +A E EEA+++ A+ + Sbjct: 1345 DCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1404 Query: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKA 1479 A + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LAE K Sbjct: 1405 AAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQ 1464 Query: 1480 AVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDD 1539 E E ++ E R + A EE + E L+R+N+ L+ E+ L + Sbjct: 1465 KCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAE 1524 Query: 1540 VGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQG 1599 GK +HELE+ + EQ +L+A + E E L E LR+++ + +K++ +R + Sbjct: 1525 GGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1584 Query: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659 +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + E Sbjct: 1585 KDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAE 1644 Query: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719 A++ R Q +K+ +++ S+E++ Q E+R L+AE+ L+ L ++R+ Sbjct: 1645 ALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERS 1704 Query: 1720 RRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779 R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ +K Sbjct: 1705 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 Query: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839 + + EL E+ SA E ++ +E+ +++L+ RL E + A K I LE++ Sbjct: 1765 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEAR 1824 Query: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899 + + E ++E E + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK Sbjct: 1825 VRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSY 1884 Query: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 KRQ EEAEE+++ A R+LQ ELE+ E A+ +V LR + R Sbjct: 1885 KRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSR 1931 Score = 224 bits (572), Expect = 5e-58 Identities = 195/932 (20%), Positives = 421/932 (45%), Gaps = 48/932 (5%) Query: 1067 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 ++E +K+K L + + EL+E+MV + +L+ Q+ + E L A R + Sbjct: 859 KEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCD------ 912 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1180 QL+K+ + +A + E E E E + ++R L +E L+ +++D TL Sbjct: 913 -QLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE 971 Query: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 ++ + + +TE L+E + L++ H Q L +L + ++ Sbjct: 972 KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN----TLT 1027 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 K ++ LE +V +L L + R + E+ +R+LE L+ Q D E + + EKL+ Sbjct: 1028 KAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLK 1087 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 + + E+ N+ + + ++ I+L K++ +A++ + +E ++ E ++ + + Sbjct: 1088 KKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSR 1147 Query: 1361 EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEA 1420 E + E+LEE A + +A+ + RR EE EA R+ ++ Sbjct: 1148 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS-- 1205 Query: 1421 LTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA--EEK 1478 +AE E +D L+R +++L++E + M+++ V T+ K + +++ E++ Sbjct: 1206 ----VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQ 1261 Query: 1479 AAVLRAVEERERA-----EAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533 + L++ EE ++ A+ + + +R L+E++ +L R +A ++E L Sbjct: 1262 LSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEEL 1321 Query: 1534 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1593 ++ K+ + L A + + + LR Q E ++ + A + V +T++ Sbjct: 1322 KRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKY 1381 Query: 1594 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1653 E D R E EE +++LA++L+ AE + + +++L+ E+E+L + Sbjct: 1382 ETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERT 1441 Query: 1654 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ--- 1710 K+ R + E ++ EET E S+K + L E+ +++ Sbjct: 1442 NAACAALDKKQRNFDKILAEWKQKCEETHAELEA-------SQKEARSLGTELFKIKNAY 1494 Query: 1711 ----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQ 1766 ++L R + QQ+ ++ +++A G + + K+Q+E +L+ LEE + Sbjct: 1495 EESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAE 1554 Query: 1767 SNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1826 ++ E + ++ L++ + +E+ +R + K E Q I+ + DA R Sbjct: 1555 ASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIR 1612 Query: 1827 ARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQ 1884 +R+ +E L + E QL R + + R + LK+ + +++ R + Sbjct: 1613 SRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQED 1672 Query: 1885 LRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNR 1944 L++QL R L+ ++EE + + R+ ++EL D +E + ++ + T+L N Sbjct: 1673 LKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINT 1732 Query: 1945 LRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 ++ + L+E ++E+A++A Sbjct: 1733 KKKLETDISQMQGEMEDILQEARNAEEKAKKA 1764 Score = 191 bits (486), Expect = 5e-48 Identities = 203/947 (21%), Positives = 416/947 (43%), Gaps = 94/947 (9%) Query: 856 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 906 TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE + Sbjct: 999 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK 1058 Query: 907 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966 +L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ Sbjct: 1059 RKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQ 1118 Query: 967 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1015 I+ELE +EAE +R K + ++ ++++ E L + + + ++ Sbjct: 1119 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1178 Query: 1016 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1057 K R+ LE+ + + AA E E++ +L +++ K E I D+ Sbjct: 1179 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238 Query: 1058 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1117 + K + LEK+ R L+ + SEL+ + EQQ+ +L AQ GR + E + + Sbjct: 1239 SNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLD 1298 Query: 1118 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1177 ++ +QL + + + E + LE E A+ + + + LR + E+ + Sbjct: 1299 EKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQE 1358 Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237 S Q SK EV + + E + ++E +++ Q L E +E Sbjct: 1359 SKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCA 1418 Query: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1297 + EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++ Sbjct: 1419 SLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1477 Query: 1298 KLQRAQA-ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356 K R+ EL + A E+ + L +E + + ++ D E + E + L + Sbjct: 1478 KEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1537 Query: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1415 +E E L+ LEE A+ E ++ Q +L++ + + + A E ++ +R Sbjct: 1538 QVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597 Query: 1416 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1475 R E++ L + + + R +++++ +L++ + L ++ + + R +L Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILK 1657 Query: 1476 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1530 + + + A+ +E + + E RA L +EE + E+ ER + EL Sbjct: 1658 DTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1717 Query: 1531 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1574 +L+++K D+ + E+E + A A + +T+ + +EL Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777 Query: 1575 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1626 +D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + E+ Sbjct: 1778 EQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836 Query: 1627 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1665 K+ AV +K E ++EL +A++ S + EEA +Q Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896 Query: 1666 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712 A+ ++L E+EE + ++++ ++ R+K E + EE Sbjct: 1897 TNLAKFRKLQHELEEAEERAD--IAESQVNKLRVKSREVHTKVISEE 1941 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 1303 bits (3371), Expect = 0.0 Identities = 728/1908 (38%), Positives = 1146/1908 (60%), Gaps = 28/1908 (1%) Query: 52 ARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMA 111 A+ +V + ++ + + VE E R L + + + MNPPKF + EDMA Sbjct: 34 AKTYCFVVDSKEEYAKGKIKSSQDGKVTVE-TEDNRTLVVKPEDVYAMNPPKFDRIEDMA 92 Query: 112 ELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVP 171 LT LNE +VL+NL++RY S +IYTYSGLFCV +NPYK LP+Y +VE YRGKKR E P Sbjct: 93 MLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAP 152 Query: 172 PHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK--GRKEPG 229 PH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A++ +K+ Sbjct: 153 PHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSK 212 Query: 230 VPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKS 289 + G LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKS Sbjct: 213 MKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKS 272 Query: 290 RAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQE 347 R Q K E S+HIFYQ+L +L LL+ + Y F++ G + E Sbjct: 273 RVTFQLKAERSYHIFYQILSNKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLA 332 Query: 348 TLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLG 407 T ++ +LGF+ EE + ++ AV+ +GN+ K+++ +QA A K L+GL Sbjct: 333 TDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKTAYLMGLN 392 Query: 408 VTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RS 466 +D +AL PR+KVG +YV K QT +Q A+ AL+K+ YE+LF W+V R+N+ LD + Sbjct: 393 SSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKL 452 Query: 467 PRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWT 526 PRQ F+G+LDIAGFEIF+ NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI WT Sbjct: 453 PRQ--HFIGVLDIAGFEIFEYNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510 Query: 527 FLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVA-QEQGGHPKFQRP 585 F+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ Q G FQ+P Sbjct: 511 FIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQKP 567 Query: 586 RHLRDQAD--FSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD--- 640 + ++ +A+ FS++HYAG VDY + WL KN DPLN+ V L +S++RL A ++ Sbjct: 568 KVVKGRAEAHFSLIHYAGTVDYSVSGWLEKNKDPLNETVVGLYQKSSNRLLAHLYATFAT 627 Query: 641 VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNH 700 + G ++V+ + + F+TV L++E+L++LM+ L T+P FVRCI+PN Sbjct: 628 ADADSGKKKVA---------KKKGSSFQTVSALFRENLNKLMSNLRTTHPHFVRCIIPNE 678 Query: 701 EKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMD 759 K G +E LVL QLRCNGVLEGIRICR+GFPNRIL+ +F+QRY +L +AIP+G F+D Sbjct: 679 TKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQFID 738 Query: 760 GKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLA 819 K+ACEK++ ++++D Y+ G +K+FF+AG+L LEE RD ++ +I QA RG+L Sbjct: 739 SKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLM 798 Query: 820 RRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQ 879 R FQK Q++ ++ +Q N +++ ++HW W +LF K+KPLL+ ++ + +E Q Sbjct: 799 RVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 858 Query: 880 KVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELEL 939 K ++ +S + EL+ ++ L +E+ L Q++AE+E +AEE +L K +LE Sbjct: 859 KTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEA 918 Query: 940 VVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKK 999 + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K Sbjct: 919 KIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 978 Query: 1000 FEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDR 1059 E+L L++ +KL++E+K L++ + EE+KV SLNK + K E + D+E Sbjct: 979 LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038 Query: 1060 LRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDE 1119 L +E+K R +LE+ KR+L+G+ QE +++ + ++L +L +K+ E ++ EDE Sbjct: 1039 LEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDE 1098 Query: 1120 GGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDST 1179 Q K ++E QA + E +E++E+ER R K EKQR D ELE L LE+ T Sbjct: 1099 QTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVT 1158 Query: 1180 NAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAW 1239 + Q EL KRE E +L++ LEE T HEA V LR++H ++ EL EQ++ +R K Sbjct: 1159 STQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKL 1218 Query: 1240 EKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKL 1299 EK + + E+ +L + + S+ ++ E+ R LE QL E +G+ + +R+ +E + Sbjct: 1219 EKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQK 1278 Query: 1300 QRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAME 1359 R Q E +S L E ES +LS+ + Q + + L+EE +AK AL +++ Sbjct: 1279 SRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSR 1338 Query: 1360 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREA 1418 + LREQ EEE + R L A +++++WR + E +A E EEA+++ A+ Sbjct: 1339 HDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRL 1398 Query: 1419 EALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1478 + +++ LE+ ++RLQ E++D +D+E+ L + L+KKQR FD++LAE K Sbjct: 1399 QDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWK 1458 Query: 1479 AAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1538 + E E + E R L A EE + E ++R+N+ L E+ L Sbjct: 1459 TKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIA 1518 Query: 1539 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1598 + GK++HELE++ + E D++ + E E L E LR+++ + +K++ +R + Sbjct: 1519 ENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIA 1578 Query: 1599 GRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKE 1658 +DE E+ +R + + + D E + R A+ +KK+EG+L E++ Q++ A + Sbjct: 1579 EKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAA 1638 Query: 1659 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDR 1718 E +K LR +Q Q+K+ +++ +E++ Q E+R L+AEV L+ L ++R Sbjct: 1639 ETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTER 1698 Query: 1719 ARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRK 1778 AR+ A+Q+ + + V + +++ K++LE L QL+ E+E+ ++ ++ +K Sbjct: 1699 ARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKK 1758 Query: 1779 LLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALES 1838 + + EL E+ SA E ++ LE+ +++L+ RL E + A K I LE+ Sbjct: 1759 AITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLET 1818 Query: 1839 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1898 ++ + E +LE E ++ S K +R+ E+R+KE+ Q EE+R+ +L+D ++K ++VK Sbjct: 1819 RIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKS 1878 Query: 1899 LKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 KRQ EEA+E+A+ R+ Q ELE+ E A+ +V LR + R Sbjct: 1879 YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQVNKLRAKTR 1926 Score = 145 bits (365), Expect = 5e-34 Identities = 188/868 (21%), Positives = 357/868 (41%), Gaps = 172/868 (19%) Query: 844 LKLRHWQWWRLFTKVKPL----LQVTRQDEVLQARAQELQ-----------KVQELQQQS 888 LK + +++ +L +KV+ LQ ++ + LQAR +EL+ K ++ + Sbjct: 1081 LKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDY 1140 Query: 889 AREVGELQGRV--------AQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELV 940 ARE+ EL R+ Q+E + R AE L+ +L + +AA +++ Sbjct: 1141 ARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200 Query: 941 VSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQ-----LEKVTTEA 995 V+EL ++ + ++++ EK + I +L + +E+ ++ L+ LE +EA Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260 Query: 996 KMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD 1055 + K E ++ S+L+ ++ L+ E S Q E+E V L++ + + + Sbjct: 1261 RGKNEE-----IQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEE 1315 Query: 1056 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALAR 1115 ++ +L +E K + L + + L+EQ E+Q+ EL+ L + E+ + Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTK 1375 Query: 1116 AEDEGGARAQLLKSLREAQAA-LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1174 E + R + L+ ++ A L +++E +E+ EK ++ L E+E L ++E Sbjct: 1376 YETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVER 1435 Query: 1175 T------LDSTNAQ-----QELRSKREQEVTELKKTLEEETRI----------HEAAVQE 1213 LD E ++K E+ EL+ +L+E + +E A+ + Sbjct: 1436 ANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQ 1495 Query: 1214 LR------QRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEG 1267 L + Q + +L EQ+ + + EK+R +E E ++++ L + A + Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555 Query: 1268 EQRRRRLELQLQEVQGR----------------------------AGDGE-RARAEAAEK 1298 E + R++L+L +V+ A D E R+R EA Sbjct: 1556 EAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRL 1615 Query: 1299 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL------QEETRAKLALG 1352 ++ + +L + L+ A + K L S + QL D Q L QE+ + +LA+ Sbjct: 1616 KKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIV 1675 Query: 1353 SR-VRAMEAEAAGLREQLEEEAAARERAGREL----------QTAQAQLSEWRRRQEEEA 1401 R ++AE LR LE+ AR+ A +EL T L +++ E + Sbjct: 1676 ERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDL 1735 Query: 1402 GALEA-----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1450 L++ EE ++A +A + + L ++ +T LER ++ L+Q + D Sbjct: 1736 MQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1795 Query: 1451 MDLEQQRQLVSTLEKKQ-----------------------------RKFDQLLAE----- 1476 L++ QL KKQ RK+++ + E Sbjct: 1796 HRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQS 1855 Query: 1477 --EKAAVLRAVE--------------ERERAEAEGREREARALSLTRALEEEQEAREELE 1520 ++ VLR + + E A+ + + LEE +E + E Sbjct: 1856 EEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAE 1915 Query: 1521 RQNRALRAELEALLSSKDDVGKSVHELE 1548 Q LRA+ SS+ VHE E Sbjct: 1916 SQVNKLRAKTRDFTSSR----MVVHESE 1939 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 1301 bits (3367), Expect = 0.0 Identities = 719/1909 (37%), Positives = 1155/1909 (60%), Gaps = 27/1909 (1%) Query: 52 ARRLVWVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAED 109 A+ V+V F A + R+ G+ A+ E +G + + DQ+ MNPPK+ K ED Sbjct: 34 AKTSVFVVDPKESFVKATVQSREGGKVTAKTE---AGATVTVKDDQVFPMNPPKYDKIED 90 Query: 110 MAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHE 169 MA +T L+E +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E Sbjct: 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQE 150 Query: 170 VPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPG 229 PPH++++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + + +KE Sbjct: 151 APPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEV 210 Query: 230 VPGE----LERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 285 G+ LE Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYL Sbjct: 211 TSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYL 270 Query: 286 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERE 343 LEKSR Q K E S+HIFYQ++ L LL+ + Y F++ G + P ++E Sbjct: 271 LEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQE 330 Query: 344 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRL 403 T ++ +LGF+ +E +S+ ++ AV+ +GN+ K+++ +QA A K L Sbjct: 331 ELMATDSAIEILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYL 390 Query: 404 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 463 L D +AL PR+KVG +YV K QT +Q A+ ALAKA Y+++F W+V R+N+ L Sbjct: 391 QNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQL 450 Query: 464 D-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 522 D + PRQ F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EG Sbjct: 451 DTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEG 508 Query: 523 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPK 581 I WTF+DFG+DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G Sbjct: 509 IEWTFIDFGMDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNN 565 Query: 582 FQRPRHLRD--QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 639 FQ+P+ + +A FS++HYAG VDY WL KN DPLN+ V L +S + A ++ Sbjct: 566 FQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLALLFV 625 Query: 640 DVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPN 699 G G E + G G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN Sbjct: 626 ---GATGAE--AEAGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPN 680 Query: 700 HEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FM 758 K G +E LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+ Sbjct: 681 ETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFI 740 Query: 759 DGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYL 818 D K+A EK++ ++++D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+L Sbjct: 741 DSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFL 800 Query: 819 ARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQEL 878 AR +QK +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ + +E Sbjct: 801 ARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEF 860 Query: 879 QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE 938 +K +E ++ + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K +LE Sbjct: 861 EKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLE 920 Query: 939 LVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMK 998 + E+ R +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K Sbjct: 921 AKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 980 Query: 999 KFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMED 1058 E++ L++ +KL+KE+K L++ + EE+KV +L K ++K E + D+E Sbjct: 981 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1040 Query: 1059 RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED 1118 L +E+K R +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ ++ ED Sbjct: 1041 SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED 1100 Query: 1119 EGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDS 1178 E QL K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ + Sbjct: 1101 EQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGA 1160 Query: 1179 TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGA 1238 T+AQ E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K Sbjct: 1161 TSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220 Query: 1239 WEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEK 1298 EK + ++ E+ +L + + ++ A+ E+ R LE QL E++ + + +R + + Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280 Query: 1299 LQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAM 1358 R Q E S L+E ++ +LS+ + Q+ + + L+EE +AK AL +++ Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340 Query: 1359 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAARE 1417 + LREQ EEE A+ R + A +++++WR + E +A E EEA+++ A+ Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400 Query: 1418 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477 + + + LE+ ++RLQ E++D +D+E+ + L+KKQR FD++LAE Sbjct: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460 Query: 1478 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSK 1537 K E E ++ E R + A EE + E L+R+N+ L+ E+ L Sbjct: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQI 1520 Query: 1538 DDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDL 1597 + GK +HELE+ + EQ ++L+A + E E L E LR+++ + +K++ +R + Sbjct: 1521 AEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKI 1580 Query: 1598 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGK 1657 +DE ++ +R + + + D E + R A+ +KK+EG+L E++ Q+ A + Sbjct: 1581 AEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1640 Query: 1658 EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASD 1717 EA++ R QA +K+ +++ S+E++ Q E+R L+AE+ L+ L ++ Sbjct: 1641 AEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1700 Query: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYR 1777 R+R+ A+Q+ + ++ V + +++ K++LE + Q++ E+E+ + ++ + Sbjct: 1701 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAK 1760 Query: 1778 KLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALE 1837 K + + EL E+ SA E ++ LE+ +++L+ RL E + A K I LE Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 Query: 1838 SKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVK 1897 +++ + E ++E E + + + K +R+ E+++KE+ Q EE+R+ +L+D ++K +VK Sbjct: 1821 ARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVK 1880 Query: 1898 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 KRQ EEAEE+++ + RR+Q ELE+ E A+ +V LR + R Sbjct: 1881 SYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSR 1929 Score = 227 bits (579), Expect = 8e-59 Identities = 203/949 (21%), Positives = 419/949 (44%), Gaps = 35/949 (3%) Query: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097 K+K L LK T +M + + EK ++EL K + + EL+E+MV Q + Sbjct: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890 Query: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157 L+ Q+ + + L A R + QL+K+ + +A + E E E E + + Sbjct: 891 LQLQVQAEADSLADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943 Query: 1158 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214 +R L +E L+ +++D TL ++ + + +TE L+E + L Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003 Query: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274 ++ H Q L +L + ++ K ++ LE +V +L L + R + E+ +R+L Sbjct: 1004 QEAHQQTLDDLQAEEDKVN----TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKL 1059 Query: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334 E L+ Q D E + + EKL++ + E+ + + + ++ ++L K++ +A++ Sbjct: 1060 EGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119 Query: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394 + +E ++ E ++ + + E + E+LEE A + +A+ + R Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179 Query: 1395 RRQEEEAGALEA-GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453 R EE EA R++ A L +++ +LE+ + ++ E+DD ++ Sbjct: 1180 RDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNM 1239 Query: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS----LTRAL 1509 E + LEK R + L+E K EE++R + + AR + +R L Sbjct: 1240 ETVSKAKGNLEKMCRALEDQLSEIKTKE----EEQQRLINDLTAQRARLQTESGEYSRQL 1295 Query: 1510 EEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELE 1569 +E+ +L R +A ++E L ++ K+ L A + + + LR Q E + Sbjct: 1296 DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQ 1355 Query: 1570 DELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQR 1629 + + A + V +T++E D R E EE +++LA++L+DAE + + Sbjct: 1356 EAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKC 1415 Query: 1630 TLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIF 1689 +++L+ E+E+L + K+ R + E ++ EET E Sbjct: 1416 ASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1475 Query: 1690 SQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKR 1749 ++R L ++ ++L R + QQ+ ++ +++A G + + K+ Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535 Query: 1750 QLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1809 Q+E +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQMKRN 1593 Query: 1810 QIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKR 1867 I+ + DA R+R+ +E L + E QL R + + R + Sbjct: 1594 HIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAI 1653 Query: 1868 LKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDV 1927 LK+ L +++ R + L++QL R L+ ++EE + + R+ ++EL D Sbjct: 1654 LKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDA 1713 Query: 1928 TESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 +E + ++ + T+L N ++ + ++E ++E+A++A Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762 Score = 189 bits (480), Expect = 2e-47 Identities = 199/947 (21%), Positives = 418/947 (44%), Gaps = 94/947 (9%) Query: 856 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 906 TK K LQ Q + LQA ++ + + + + ++V +L+G + Q LE + Sbjct: 997 TKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1056 Query: 907 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966 +L L+ E + E + +L + ++ E +S L++++ +E+ Q+Q + K LQ Sbjct: 1057 RKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQ 1116 Query: 967 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1015 I+ELE +EAE +R K + ++ ++++ E L + + + ++ Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176 Query: 1016 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1057 K R+ LE+ + + AA E E++ +L +++ K E I D+ Sbjct: 1177 KMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236 Query: 1058 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1117 + K + LEK+ R L+ + SE++ + EQQ+ +L AQ R + E + + Sbjct: 1237 SNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLD 1296 Query: 1118 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1177 ++ +QL + + + E + LE E A++ + + + LR + E+ + Sbjct: 1297 EKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQE 1356 Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237 + Q SK EV + + E + ++E +++ Q L + E +E Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCA 1416 Query: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1297 + EKT+ L+ EV +L ++ A ++++R + L E + + + A EA++ Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE-THAELEASQ 1475 Query: 1298 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356 K R+ EL + A E+ + L +E + + ++ D E + E + L + Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535 Query: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1415 +E E + L+ LEE A+ E ++ Q +L++ + + + A E ++ +R Sbjct: 1536 QVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHI 1595 Query: 1416 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLA 1475 R E++ L + + + R +++++ +L++ + L ++ + + R +L Sbjct: 1596 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILK 1655 Query: 1476 EEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL----- 1530 + + + A+ +E + + E RA L +EE + E+ ER + EL Sbjct: 1656 DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASE 1715 Query: 1531 ---------EALLSSKD----DVGKSVHELERACRVAEQAANDLRAQVTE---LEDELTA 1574 +L+++K D+ + E+E + A A + +T+ + +EL Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775 Query: 1575 AEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDEER 1626 +D LE + L+ Q +DLQ R DEA G+++ ++L ++R+ E E + E+ Sbjct: 1776 EQDTSAHLERMKKNLE-QTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834 Query: 1627 KQRTLAVAARKKLEGELEEL---------------------KAQMASAGQGKEEAVKQLR 1665 K+ AV +K E +++EL +A++ S + EEA +Q Sbjct: 1835 KRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894 Query: 1666 KMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712 ++ + + E+EE + ++++ ++ R+K E + EE Sbjct: 1895 VNLSKFRRIQHELEEAEERAD--IAESQVNKLRVKSREVHTKIISEE 1939 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 1300 bits (3364), Expect = 0.0 Identities = 721/1873 (38%), Positives = 1125/1873 (60%), Gaps = 21/1873 (1%) Query: 84 ESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCV 143 E G L + DQ+ MNPPK+ K EDMA +T L+E VL+NL+ERY + +IYTYSGLFCV Sbjct: 67 EGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCV 126 Query: 144 VINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAG 203 +NPYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DRE+QSIL TGESGAG Sbjct: 127 TVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAG 186 Query: 204 KTENTKKVIQYLAHVASSPKGRKEPG--VPGELERQLLQANPILEAFGNAKTVKNDNSSR 261 KT NTK+VIQY A +A + + +K+ + G LE Q++ ANP+LEAFGNAKTV+NDNSSR Sbjct: 187 KTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSR 246 Query: 262 FGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLL 321 FGKFIRI+F G + A+IETYLLEKSR Q K E S+HIFYQ+ L LL+ Sbjct: 247 FGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLI 306 Query: 322 EPCSH-YRFLTNGPSSSPG-QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIA 379 + Y F++ G + P ++E T ++ +LGF+ EE +S+ ++ AV+ +GN+ Sbjct: 307 TTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMK 366 Query: 380 LKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFA 439 K+++ +QA A K L L D +AL PR+KVG +YV K QT +Q A Sbjct: 367 FKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNA 426 Query: 440 LEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYT 498 + ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS EQLCIN+T Sbjct: 427 VGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCINFT 484 Query: 499 NEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEEC 558 NEKLQQ FNH MFVLEQEEY++EGI WTF+DFG+DL CI+LIE+P G+ ++L+EEC Sbjct: 485 NEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPL---GIFSILEEEC 541 Query: 559 WFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLMKNM 615 FPKATD SF K+ Q G FQ+P+ ++ +A+ FS++HYAG VDY WL KN Sbjct: 542 MFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNK 601 Query: 616 DPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYK 675 DPLND V L +S + A ++ E SS G + + F+TV L++ Sbjct: 602 DPLNDTVVGLYQKSAMKTLASLFSTY---ASAEADSS---AKKGAKKKGSSFQTVSALFR 655 Query: 676 ESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNR 735 E+L++LM L +T+P FVRCI+PN K G +E LVL QLRCNGVLEGIRICR+GFP+R Sbjct: 656 ENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSR 715 Query: 736 ILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQ 794 IL+ +F+QRY++L +AIP+G F+D K+A EK++ ++++D Y+ G +K+FF+AG+L Sbjct: 716 ILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGL 775 Query: 795 LEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRL 854 LEE RD K+ II QA RG+L R +QK Q++ AL +Q N A++ ++HW W +L Sbjct: 776 LEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKL 835 Query: 855 FTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLR 914 F K+KPLL+ ++ + +E QK ++ +S + EL+ ++ L +E+ L Q++ Sbjct: 836 FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQ 895 Query: 915 AEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEA 974 +EA+ A+AEE +L K +LE + E+ R EEEE + ++ +K++L+ EL+ Sbjct: 896 SEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKK 955 Query: 975 HLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAE 1034 ++ E K++ EK TE K+K E++ L++ +KLSKE+K L++ + Sbjct: 956 DIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQA 1015 Query: 1035 EEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1094 EE+KV L K + K E + D+E L +E+K R +LE+ KR+L+G+ QE ++ + Sbjct: 1016 EEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEND 1075 Query: 1095 AEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKA 1154 ++L +L +KE E+ +++ EDE QL K ++E QA + E E++E+ER +R KA Sbjct: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135 Query: 1155 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214 EKQR DL ELE + LE+ +T+AQ EL KRE E +L++ LEE T HEA V L Sbjct: 1136 EKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAAL 1195 Query: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274 R++H ++ EL EQ++ +R K EK + L+ E +L + ++ A+ E+ R L Sbjct: 1196 RKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL 1255 Query: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334 E Q+ E++ + + +R + + R Q E S L+E ++ +LS+ ++ Q+ Sbjct: 1256 EDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQI 1315 Query: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394 + + L+EET+AK AL +++ + LREQ EEE + R L A +++++WR Sbjct: 1316 EELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 1375 Query: 1395 RRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453 + E +A E EEA+++ A+ + + + LE+ ++RLQ E++D +D+ Sbjct: 1376 TKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDV 1435 Query: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQ 1513 E+ + L+KKQR FD++L+E K E E ++ E R + EE Sbjct: 1436 ERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESL 1495 Query: 1514 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1573 + E L R+N+ L+ E+ L + GK +HELE+ + EQ +++A + E E L Sbjct: 1496 DQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLE 1555 Query: 1574 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1633 E LR+++ + +K++ +R + +DE ++ +R + + + D E + R A+ Sbjct: 1556 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDAL 1615 Query: 1634 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1693 +KK+EG+L E++ Q+ A + E+++ R Q +KE +++ +E++ Q Sbjct: 1616 RVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLA 1675 Query: 1694 ESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEG 1753 E+R L+AE+ L L ++R+R+ A+Q+ + ++ V + +++ K++LE Sbjct: 1676 IVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLEN 1735 Query: 1754 RLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQE 1813 + QL+ E+EE S ++ +K + + EL E+ SA E ++ LE+ +++ Sbjct: 1736 DVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1795 Query: 1814 LRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVL 1873 L+ RL E + A K I LE+++ + E ++E E + + K +R+ E+R+KE+ Sbjct: 1796 LQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTY 1855 Query: 1874 QVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAES 1933 Q EE+R+ +L+D ++K +VK KRQ EEAEE+++ + R+LQ ELE+ E A+ Sbjct: 1856 QTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADI 1915 Query: 1934 MNREVTTLRNRLR 1946 +V LR + R Sbjct: 1916 AESQVNKLRVKSR 1928 Score = 227 bits (579), Expect = 8e-59 Identities = 234/997 (23%), Positives = 455/997 (45%), Gaps = 114/997 (11%) Query: 856 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 906 +K K LQ T Q + LQA ++ + + + + ++V +L+G + Q LE + Sbjct: 996 SKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAK 1055 Query: 907 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966 +L L+ E + E + +L + ++ E +S L +++ +E+ Q+Q + K LQ Sbjct: 1056 RKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQ 1115 Query: 967 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1026 I+EL +EAE +R K + ++ ++++ E L E+ S + +L + R A Sbjct: 1116 ARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERL---EEAGGATSAQVELNKKREA 1172 Query: 1027 EFSSQAAEEEEKVKS----LNKLRLKYEATIADM----------EDRLRKEE-------- 1064 EF + EE + LR K+ ++A++ + +L KE+ Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETD 1232 Query: 1065 ----------KGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALA 1114 K + LEK+ R L+ + SEL+ + EQQ+ +L AQ R + E Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292 Query: 1115 RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED 1174 + +++ +QL +S + + + E + LE E A+ + + + LR + E+ Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352 Query: 1175 TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1234 + Q SK EV + + E + ++E +++ Q L E E +E Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412 Query: 1235 GKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAE 1294 + EKT+ L+ EV +L ++ A ++++R + L E + + + + A E Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQ-AELE 1471 Query: 1295 AAEKLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1353 A++K R+ EL V E+ + L +E + + ++ D E + E + L Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEK 1531 Query: 1354 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRR 1413 + +E E ++ LEE A+ E ++ Q +L++ + + Sbjct: 1532 IKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVD--------------- 1576 Query: 1414 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1473 +++AEK E +D+L+R R+ + + +T+D E + + + KK+ + D Sbjct: 1577 ---------RKIAEKDEEIDQLKRNHTRVVETMQ-STLDAEIRSRNDALRVKKKMEGDLN 1626 Query: 1474 LAE---EKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL---ERQNRALR 1527 E A L A R +G +E + L L AL +++ +E+L ER+ L+ Sbjct: 1627 EMEIQLNHANRLAAESLRNYRNTQGILKETQ-LHLDDALRGQEDLKEQLAIVERRANLLQ 1685 Query: 1528 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1587 AE+E L ++ + + ER+ ++AEQ D +V L + T+ + K +LE V Sbjct: 1686 AEIEELWAT-------LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVS 1738 Query: 1588 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV---AARKKLEGELE 1644 L+++ E +Q A E+ + K + DA + +E +K++ + +K LE ++ Sbjct: 1739 QLQSEVEEVIQESRNAEEKAK----KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVK 1794 Query: 1645 ELKAQMASAGQ-GKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLE 1703 +L+ ++ A Q + KQ++K++A+++EL EVE + E R+ E+R+K L Sbjct: 1795 DLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELT 1854 Query: 1704 AE-------VLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLG 1756 + VLRLQ+ L +A+ ++ + + E A+E +N NLSK Sbjct: 1855 YQTEEDRKNVLRLQD-LVDKLQAKVKSYKRQAEEAEEQSNANLSK-------------FR 1900 Query: 1757 QLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE 1793 +L+ ELEE + +++ + KL ++ + T++SAE Sbjct: 1901 KLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937 Score = 219 bits (557), Expect = 3e-56 Identities = 205/953 (21%), Positives = 425/953 (44%), Gaps = 43/953 (4%) Query: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097 K+K L LK T +M + +K + EL K + + EL+E+MV + + Sbjct: 838 KIKPL----LKSAETEKEMATMKEEFQKTKDELAKS----EAKRKELEEKMVTLLKEKND 889 Query: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157 L+ Q+ + + L A R E QL+K+ + +A + E E E E + + Sbjct: 890 LQLQVQSEADSLADAEERCE-------QLIKNKIQLEAKIKEVTERAEEEEEINAELTAK 942 Query: 1158 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214 +R L +E L+ +++D TL ++ + + +TE L+E + L Sbjct: 943 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKAL 1002 Query: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274 ++ H Q L +L + ++ K + LE +V +L L + R + E+ +R+L Sbjct: 1003 QETHQQTLDDLQAEEDKVN----ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKL 1058 Query: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334 E L+ Q D E + + EKL++ + E+ N+ + + ++ I+L K++ +A++ Sbjct: 1059 EGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARI 1118 Query: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394 + E ++ E ++ + + E + E+LEE A + +A+ + R Sbjct: 1119 EELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLR 1178 Query: 1395 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM--- 1451 R EE EA A R+ ++ +AE E +D L+R +++L++E + M Sbjct: 1179 RDLEEATLQHEAMVAALRKKHADS------MAELGEQIDNLQRVKQKLEKEKSELKMETD 1232 Query: 1452 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERA----EAEGREREARALSLTR 1507 DL + +S + K + L ++ + + EE++R A+ + A +R Sbjct: 1233 DLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSR 1292 Query: 1508 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1567 L+E+ +L R +A ++E L ++ K+ + L A + + + LR Q E Sbjct: 1293 QLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEE 1352 Query: 1568 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1627 ++ + A + V +T++E D R E EE +++LA++L++AE + Sbjct: 1353 EQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 1412 Query: 1628 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1687 + +++L+ E+E+L + + K+ R + E ++ EET+ E Sbjct: 1413 KCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEA 1472 Query: 1688 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1747 ++R L ++ ++L R + QQ+ ++ +++A G + + Sbjct: 1473 SQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKI 1532 Query: 1748 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1807 K+Q+E +++ LEE +++ E + ++ L++ + +E+ +R + K E Q Sbjct: 1533 KKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKDEEIDQLK 1590 Query: 1808 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1865 + + DA R+R+ +E L + E QL R S + R + Sbjct: 1591 RNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650 Query: 1866 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1925 LKE L +++ R + L++QL R L+ ++EE + + R+ ++EL Sbjct: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELL 1710 Query: 1926 DVTESAESMNREVTTLRNRLRR--GPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 D +E + ++ + T+L N ++ ++ V +V ++E ++E+A++A Sbjct: 1711 DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV--IQESRNAEEKAKKA 1761 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 1300 bits (3363), Expect = 0.0 Identities = 754/1919 (39%), Positives = 1124/1919 (58%), Gaps = 33/1919 (1%) Query: 48 VEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKA 107 + W ++ VWVP E + A ++ E + + L + ++Q MNPP+F Sbjct: 69 IPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLL 128 Query: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167 EDMA +T LNEASVLHNLR+RY +IYTYSGLFCV INPYK LP+YT ++V Y+GK+R Sbjct: 129 EDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRR 188 Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227 + PPH+YAV + AY ML++R++QS+L TGESGAGKT NTK+VIQY A VA+ G + Sbjct: 189 SDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGK 248 Query: 228 PG------VPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANI 281 G LE Q+++ANP +EAFGNAKT++NDNSSRFGKFIRI+F +G + A+I Sbjct: 249 KAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADI 308 Query: 282 ETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPGQ 340 ++YLLEKSR I Q E S+H++YQ+L G +L+ LLL + Y F + G + Sbjct: 309 DSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITVDNM 368 Query: 341 -ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQK 399 + E T ++ +LGFS +E + ++V A+L FGN+ K+++ +QA +A K Sbjct: 369 NDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADK 428 Query: 400 LCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRL 459 L+G+ D + LL PR++VG +YV K Q+ EQ FA+ ALAKATY+RLFRWLV R+ Sbjct: 429 AAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRI 488 Query: 460 NRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEY 518 N+ LD + PRQ F+G+LDIAGFEIF+ NSFEQLCIN+TNEKLQQ FN MFVLEQEEY Sbjct: 489 NQTLDTKLPRQ--FFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEY 546 Query: 519 QREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG 578 +REGI W F+DFGLDLQPCIDLIE+P G+L++L+EEC FPKA+D SF K+ G Sbjct: 547 KREGIDWVFIDFGLDLQPCIDLIEKPL---GILSILEEECMFPKASDASFRAKLYDNHAG 603 Query: 579 H-PKFQRPR---HLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLT 634 P FQ+PR + QA F V+HYAG V Y WL KN DPLN+ V + +S +RL Sbjct: 604 KSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLL 663 Query: 635 AEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 694 A ++++ G E S G R + F+TV QL+KE+L++LM L T P FVR Sbjct: 664 ATLYENYAGSCSTEPPKS---GVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVR 720 Query: 695 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 754 CIVPN K G ++ LVL QLRCNGVLEGIRICRQGFPNR+L+ +FRQRY IL P+AIP Sbjct: 721 CIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIP 780 Query: 755 KG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAA 813 FMD ++A EK++ +L+LD Y+ G +K+FF+AG+L LEE RD ++ ++ QA Sbjct: 781 DDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQAR 840 Query: 814 ARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQA 873 +RG L R +Q+ + AL +Q N A+ +++W W +LF K+KPLL+ + +E L A Sbjct: 841 SRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAA 900 Query: 874 RAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAAR 933 EL+ ++ + + EL+ + +E+ LA QL+AE + A+AEE L Sbjct: 901 LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKS 960 Query: 934 KQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTT 993 K +LE V EL R+ +EEE + + +++L+ EL+ ++ + K + EK T Sbjct: 961 KVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQAT 1020 Query: 994 EAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATI 1053 E K+K E++ L++ ++L+KE+K L++ + EE++V +L K +L+ E + Sbjct: 1021 ENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQV 1080 Query: 1054 ADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAAL 1113 D+E L +E+K R + E+ KR+L+G+ QE + + Q ++L +L +K+ EL Sbjct: 1081 EDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLS 1140 Query: 1114 ARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE 1173 R EDE AQ+ K ++E QA E +E+LE+ER AR + EKQR + ELE L LE Sbjct: 1141 LRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLE 1200 Query: 1174 DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQAR 1233 + ++ Q+E KRE E+ L++ LEE HEA V LR++ + EL EQ++ + Sbjct: 1201 EAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQ 1260 Query: 1234 RGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARA 1293 R + EK + L EV +L A + +L A+ E+ R E QL E + + + +R A Sbjct: 1261 RVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLA 1320 Query: 1294 EAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS 1353 +A+ + R Q E +S L E E +LS+ + L + + L+EE++AK AL Sbjct: 1321 DASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAH 1380 Query: 1354 RVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARR 1412 V+A+ + LREQ EEEA A+ R L A A++++WR + E +A E EEA++ Sbjct: 1381 AVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKK 1440 Query: 1413 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1472 + A + + + LE+ + RLQ E +D T++LE+ + L+KKQR ++ Sbjct: 1441 KLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLER 1500 Query: 1473 LLAEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEEEQEAREELERQNRALR 1527 L E R EE + E E +RE+R L L EE EA E L+R+N+ L+ Sbjct: 1501 ALEER-----RRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQ 1555 Query: 1528 AELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQ 1587 E+ L GKS+ ELE+ + E ++++A + E E L E LR+++ + Sbjct: 1556 EEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELS 1615 Query: 1588 ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELK 1647 +K + +R L +DE RR + + + D E + R A+ +KK+EG+L +L+ Sbjct: 1616 QVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLE 1675 Query: 1648 AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVL 1707 Q+ A + EA R MQAQ+KE +E + E+ Q + E+R L AE+ Sbjct: 1676 LQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELE 1735 Query: 1708 RLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQS 1767 L+ L +R+RR A+Q+ E + + + +L +K++LE L QL E+EE Sbjct: 1736 ELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQ 1795 Query: 1768 NSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARA 1827 ++ +K + + EL E+ SA E ++ LE+ ++EL+ RL E + A Sbjct: 1796 ERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALR 1855 Query: 1828 RHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRD 1887 K + LE+K+ + E +L+ E ++ + K VR+ E+R+KE+ Q EE+R+ +++D Sbjct: 1856 GGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQD 1915 Query: 1888 QLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 ++K +VK KRQ EEAE++A+ A R+ Q EL+D E A+ + LR R R Sbjct: 1916 LVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTR 1974 Score = 249 bits (637), Expect = 1e-65 Identities = 234/935 (25%), Positives = 414/935 (44%), Gaps = 60/935 (6%) Query: 1067 RQELEKLKRRL---DGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 R EL L+ L + + EL+E V Q +L QL +++ L A R Sbjct: 902 RAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCH------ 955 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED---TLDSTN 1180 L+KS + + + E E LE E +RR L +E L+ +++D TL Sbjct: 956 -LLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAE 1014 Query: 1181 AQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWE 1240 +++ + + +TE L+E + L++ H QALG+L Q E+ R A Sbjct: 1015 KEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDL--QAEEDR--VSALT 1070 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 K +L LE +V +L L + R + E+ +R+LE L+ Q D + + + EKL+ Sbjct: 1071 KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLK 1130 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEA 1360 + +EL +S + + + ++ K++ +A+ + L+EE A+ A +RV A Sbjct: 1131 KKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE----LEEELEAERAARARVEKQRA 1186 Query: 1361 EAAG----LREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAR 1416 EAA L E+LEE A + +A+L RR EE A EA A RR Sbjct: 1187 EAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQA 1246 Query: 1417 EAEALTQRLAEKTETVDR----LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQ 1472 E A L E+ +++ R LE+ + L+ E+DD ++E + ++ EK R ++ Sbjct: 1247 EGAA---ELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYED 1303 Query: 1473 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1532 L+E K V + A + + + L+R LEE++ +L R LE Sbjct: 1304 QLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE 1363 Query: 1533 LLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQ 1592 L ++ K+ L A + + LR Q E + + + V +++ Sbjct: 1364 LRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSK 1423 Query: 1593 HERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMAS 1652 +E D R E EE +++LA +L++AE + + + A+ +L+ E E++ ++ Sbjct: 1424 YEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLEL-- 1481 Query: 1653 AGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQ-- 1710 E A + + + L R +EE R EE+ + +++ +GL E+ RL+ Sbjct: 1482 -----ERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHG 1536 Query: 1711 -----EELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEE 1765 E L R + Q++ ++ D+V+ S + + K+ LEG +++ LEE Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596 Query: 1766 QSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG---RQQLERQIQELRGRLGEED 1822 + EL + + L +Q+E + +R + K E R+ +R ++ L+ L D Sbjct: 1597 EGALEL--EETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASL---D 1651 Query: 1823 AGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERR 1880 A RAR++ +E L E QL TR+ + R + +LKE +EE+R Sbjct: 1652 AETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQR 1711 Query: 1881 VADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTT 1940 +A +L +Q + R L +LEE + + RR ++EL + TE ++ + T Sbjct: 1712 LAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTG 1771 Query: 1941 LRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975 L N+ ++ + +EE EAEE Sbjct: 1772 LLNQKKK----LEADLAQLSGEVEEAAQERREAEE 1802 Score = 199 bits (507), Expect = 2e-50 Identities = 241/979 (24%), Positives = 408/979 (41%), Gaps = 183/979 (18%) Query: 856 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-----LEEERAR 908 TK K LQ Q + LQA + + + + + ++V +L+ + Q ++ ERA+ Sbjct: 1042 TKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAK 1101 Query: 909 --LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966 L L+ E A+A + + +L + ++ + +S+L RV +E+ QMQ + K LQ Sbjct: 1102 RKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1161 Query: 967 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLA 1026 +ELE LEAE AR +++ ++ ++++ E L E+ + +R+ R A Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERL---EEAGGASAGQREGCRKREA 1218 Query: 1027 EFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL-------EKLKRRLDG 1079 E E EE L++EAT+A + RK+ +G EL ++++++L+ Sbjct: 1219 ELGRLRRELEEAA-------LRHEATVAALR---RKQAEGAAELGEQVDSLQRVRQKLEK 1268 Query: 1080 ESSELQEQM------VEQQQRAEELRAQLGR-----------KEEELQAALA-------R 1115 E SEL+ ++ VE RA+ +L R K EELQ LA R Sbjct: 1269 EKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGR 1328 Query: 1116 AEDEGGARAQLLK---------SLREAQAA--LAEAQEDLESERVARTKAEKQRRDLGEE 1164 + E G ++LL+ S +A AA L E + LE E A++ + L + Sbjct: 1329 LQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHD 1388 Query: 1165 LEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGE 1224 + LR + E+ ++ Q L SK EV + + E + ++E +++ L E Sbjct: 1389 CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQE 1448 Query: 1225 LAEQLEQARRGKGAWEKTRLALEAEVSELRAELS------------------SLQTARQE 1266 E +E A + EK +L L+ E ++ EL +L+ R++ Sbjct: 1449 AEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ 1508 Query: 1267 GEQRRRRLELQLQEVQG------RAGDGERARAEAAEKLQRA------------------ 1302 E+ +R LE +E +G R G EA E L+R Sbjct: 1509 EEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLS 1568 Query: 1303 ---------------------QAELENVSGALNEAESKTIRLSKELSSTEAQL------- 1334 QA LE GAL E+KT+R+ ELS +A++ Sbjct: 1569 GKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEK 1628 Query: 1335 ---------------HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERA 1379 Q L ETRA+ + ME + L QL A Sbjct: 1629 DEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEA 1688 Query: 1380 GRELQTAQAQLSEWRR-RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERG 1438 + QAQL E + R EE+ A E E+A+ R A L L E +++ ER Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQA-LERRASLLAAELEELRAALEQGERS 1747 Query: 1439 RRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER 1498 RR +QEL +AT L + L +++K + LA+ V A +ER AE + ++ Sbjct: 1748 RRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKA 1807 Query: 1499 EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAA 1558 A + L++EQ+ LER + L ++V EL+ AEQAA Sbjct: 1808 ITDAAMMAEELKKEQDTSAHLERMKKTLE--------------QTVRELQARLEEAEQAA 1853 Query: 1559 -NDLRAQVTELEDELTAAEDAKLR-LEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLR 1616 + QV +LE AK+R LE + A + +H L+G R+ ++++ Sbjct: 1854 LRGGKKQVQKLE--------AKVRELEAELDAEQKKHAEALKGV--------RKHERRVK 1897 Query: 1617 DAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWR 1676 + + +E+RK KL+ +++ K Q A Q + + RK Q ++ + Sbjct: 1898 ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEE 1957 Query: 1677 EVEETRTSREEIFSQNRES 1695 + T ++ ++ R++ Sbjct: 1958 RADMAETQANKLRARTRDA 1976 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 1295 bits (3351), Expect = 0.0 Identities = 726/1905 (38%), Positives = 1145/1905 (60%), Gaps = 30/1905 (1%) Query: 57 WVPSELHGFEAAAL--RDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELT 114 +VP + F A + R+ G+ AE E +G+ + + DQ+ + NPPKF K EDMA LT Sbjct: 38 FVPDDKEEFVKAKILSREGGKVIAETE---NGKTVTVKEDQVLQQNPPKFDKIEDMAMLT 94 Query: 115 CLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHV 174 L+E +VL NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+ Sbjct: 95 FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154 Query: 175 YAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS-SPKGRKEPGVP-- 231 +++++ AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A+ +G+K+ Sbjct: 155 FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANK 214 Query: 232 GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRA 291 G LE Q++QANP LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR Sbjct: 215 GTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRV 274 Query: 292 IRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETL 349 I Q K E ++HIFYQ+L +L LL+ + Y F++ G S + E T Sbjct: 275 IFQLKAERNYHIFYQILSNKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATD 334 Query: 350 ESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVT 409 + VLGF+ EE + ++ A++ +GN+ K+++ +QA A K L+GL Sbjct: 335 SAFDVLGFTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSA 394 Query: 410 DFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPR 468 D + L PR+KVG +YV K Q+ +Q +++ ALAKA YE++F W+V R+N L+ + PR Sbjct: 395 DLLKGLCHPRVKVGNEYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQPR 454 Query: 469 QGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFL 528 Q F+G+LDIAGFEIF NSFEQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI WTF+ Sbjct: 455 Q--YFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFI 512 Query: 529 DFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRH 587 DFG+DLQ CIDLIE+P G++++L+EEC FPKATD +F K+ G FQ+PR+ Sbjct: 513 DFGMDLQACIDLIEKPM---GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRN 569 Query: 588 LR--DQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIV 645 ++ +A FS++HYAG VDY WL KN DPLN+ V AL +S+ +L A ++ Sbjct: 570 IKGKQEAHFSLIHYAGTVDYNILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYA--- 626 Query: 646 GLEQVSSLGDG--PPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703 + GD GG+ + F+TV L++E+L++LM L T+P FVRCI+PN K Sbjct: 627 ----TADTGDSGKSKGGKKKGSSFQTVSALHRENLNKLMTNLRTTHPHFVRCIIPNERKA 682 Query: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQ 762 G ++ LV+ QLRCNGVLEGIRICR+GFPNRIL+ +FRQRY IL P AIP+G F+D ++ Sbjct: 683 PGVMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPVAIPEGQFIDSRK 742 Query: 763 ACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRA 822 EK++ +L++D N Y+ G +K+FF+AG+L LEE RD +++ II QA ARG L R Sbjct: 743 GTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRMQAQARGQLMRIE 802 Query: 823 FQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQ 882 F+K +++ AL V+Q N A++ +++W W +L+ K+KPLL+ ++ + +E +++ Sbjct: 803 FKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIK 862 Query: 883 ELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVS 942 E ++S EL+ ++ L +E+ L Q++AE + +AEE +L K +LE V Sbjct: 863 ETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVK 922 Query: 943 ELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEE 1002 E+ R+ +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K E Sbjct: 923 EMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 982 Query: 1003 DLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRK 1062 ++ L++ +KL+KE+K L++ + EE+KV SL+K ++K E + D+E L + Sbjct: 983 EMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQ 1042 Query: 1063 EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1122 E+K R +LE+ KR+L+G+ QE +++ + +L +L +KE ++ ++ EDE Sbjct: 1043 EKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVL 1102 Query: 1123 RAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQ 1182 QL K L+E QA + E +E+LE+ER AR K EK R DL ELE + LE+ +T+ Q Sbjct: 1103 ALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQ 1162 Query: 1183 QELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKT 1242 E+ KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K EK Sbjct: 1163 IEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1222 Query: 1243 RLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRA 1302 + + E+ ++ + + + A+ E+ R LE Q E + + + +R+ + + + Sbjct: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKL 1282 Query: 1303 QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEA 1362 Q E ++ L E E+ +L++ S Q+ D + L+EE +AK AL +++ + Sbjct: 1283 QTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDC 1342 Query: 1363 AGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEAL 1421 LREQ EEE A+ R L A +++++WR + E +A E EEA+++ A+ + Sbjct: 1343 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDA 1402 Query: 1422 TQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAV 1481 + + LE+ + RLQ E++D +D+E+ + L+KKQR FD++LAE K Sbjct: 1403 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKY 1462 Query: 1482 LRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVG 1541 + E E ++ E R L A EE E E +R+N+ L+ E+ L + G Sbjct: 1463 EESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGG 1522 Query: 1542 KSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRD 1601 K+VHELE+ + E +L++ + E E L E LR ++ +K + ER L +D Sbjct: 1523 KNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKD 1582 Query: 1602 EAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAV 1661 E E+ +R + + + D E + R + +KK+EG+L E++ Q++ A + EA Sbjct: 1583 EEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQ 1642 Query: 1662 KQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARR 1721 KQ++ +Q+ +K+ ++++ + +++ E+R L+AE+ L+ + ++R+R+ Sbjct: 1643 KQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRK 1702 Query: 1722 QAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLL 1781 A+Q+ E ++ V + +++ +K+++E L QL+ E+EE ++ +K + Sbjct: 1703 LAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAIT 1762 Query: 1782 QVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLA 1841 + EL E+ SA E ++ +E+ I++L+ RL E + A K + LE+++ Sbjct: 1763 DAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVR 1822 Query: 1842 QAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKR 1901 + E +LE E + S K +R++E+R+KE+ Q EE+++ +L+D ++K L+VK KR Sbjct: 1823 ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKR 1882 Query: 1902 QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 Q EEAEE+A+ + R++Q EL++ E A+ +V LR + R Sbjct: 1883 QAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSR 1927 Score = 236 bits (601), Expect = 2e-61 Identities = 213/954 (22%), Positives = 431/954 (45%), Gaps = 57/954 (5%) Query: 1044 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1103 K++ ++ + E KEE GR +++ + + EL+E+MV Q +L+ Q+ Sbjct: 837 KIKPLLKSAETEKEMATMKEEFGR--IKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQ 894 Query: 1104 RKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGE 1163 +++ L A R + QL+K+ + +A + E E LE E + ++R L + Sbjct: 895 AEQDNLNDAEERCD-------QLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLED 947 Query: 1164 ELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQ 1220 E L+ +++D TL ++ + + +TE L+E + L++ H Q Sbjct: 948 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007 Query: 1221 ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQE 1280 AL +L Q+E+ + + K+++ LE +V +L L + R + E+ +R+LE L+ Sbjct: 1008 ALDDL--QVEEDK--VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063 Query: 1281 VQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQEL 1340 Q D E + + EKL++ + ++ + + + + ++L K+L +A++ + +E Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEE 1123 Query: 1341 LQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE 1400 L+ E A+ + + E + E+LEE A + +A+ + RR EE Sbjct: 1124 LEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEA 1183 Query: 1401 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQE-------LDDATMDL 1453 EA A R+ ++ +AE E +D L+R +++L++E LDD T ++ Sbjct: 1184 TLQHEATAAALRKKHADS------VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNM 1237 Query: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQ 1513 EQ + + LEK R + E + + A + + + L R LEE++ Sbjct: 1238 EQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKE 1297 Query: 1514 EAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELT 1573 +L R + ++E L ++ GK+ + L A + A + LR Q E + Sbjct: 1298 ALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKA 1357 Query: 1574 AAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAV 1633 + + V +T++E D R E EE +++LA++L+DAE + + + Sbjct: 1358 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLE 1417 Query: 1634 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1693 + +L+ E+E+L + + K+ R + E ++ EE+++ E Sbjct: 1418 KTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELES------ 1471 Query: 1694 ESEKRLKGLEAEVLRLQ-------EELAASDRARRQAQQDRDEMADEVANGNLSKAAILE 1746 S+K + L E+ +L+ E L R + Q++ ++ +++ G + + + Sbjct: 1472 -SQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK 1530 Query: 1747 EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AESG 1803 ++QLE +L+ LEE +++ E + + L+ + E+ ER + K E Sbjct: 1531 VRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI--ERKLAEKDEEMEQA 1588 Query: 1804 RQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLV 1861 ++ +R + L+ L DA R+R+++ +E L + E QL R + K V Sbjct: 1589 KRNHQRVVDSLQTSL---DAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQV 1645 Query: 1862 RRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQ 1921 + + LK+ +Q+++ R D L++ + R L+ +LEE + + R+ + Sbjct: 1646 KSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE 1705 Query: 1922 RELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975 +EL + +E + ++ + T+L N+ ++ T + +EE V AEE Sbjct: 1706 QELIETSERVQLLHSQNTSLINQKKKMESDLT----QLQSEVEEAVQECRNAEE 1755 Score = 71.2 bits (173), Expect = 9e-12 Identities = 71/306 (23%), Positives = 140/306 (45%), Gaps = 25/306 (8%) Query: 877 ELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL---CAEAEETRGRLAAR 933 +L + ++ ++V LQ + L++ + +L + +RA +L A E L A Sbjct: 1630 QLSHANRMAAEAQKQVKSLQ---SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1686 Query: 934 KQELELVVSELEA--RVGEEE--ECSRQMQ----------TEKKRLQQHIQELEAHLE-- 977 +EL VV + E ++ E+E E S ++Q +KK+++ + +L++ +E Sbjct: 1687 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEA 1746 Query: 978 AEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEE 1037 +E + + +K T+A M E+L +D ++ L + +K +E + + + E E+ Sbjct: 1747 VQECRNAEEKAKKAITDAAM--MAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQ 1804 Query: 1038 -KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAE 1096 +K K K EA + ++E L E+K E K R+ + EL Q E ++ Sbjct: 1805 IALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLL 1864 Query: 1097 ELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEK 1156 L+ + + + +++A +AE+ L R+ Q L EA+E + K Sbjct: 1865 RLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRA 1924 Query: 1157 QRRDLG 1162 + RD+G Sbjct: 1925 KSRDIG 1930 >gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo sapiens] Length = 1939 Score = 1285 bits (3326), Expect = 0.0 Identities = 707/1900 (37%), Positives = 1141/1900 (60%), Gaps = 25/1900 (1%) Query: 59 PSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNE 118 P E + R+ G+ A+ E +G + + DQ+ MNPPK+ K EDMA +T L+E Sbjct: 43 PKESYVKAIVQSREGGKVTAKTE---AGATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHE 99 Query: 119 ASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVT 178 +VL+NL+ERY + +IYTYSGLFCV +NPYK LP+Y +V YRGKKR E PPH+++++ Sbjct: 100 PAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSIS 159 Query: 179 EGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVA-SSPKGRKEPG---VPGEL 234 + AY+ ML DRE+QSIL TGESGAGKT NTK+VIQY A +A + K ++EP + G L Sbjct: 160 DNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEPASGKMQGTL 219 Query: 235 ERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQ 294 E Q++ ANP+LEAFGNAKTV+NDNSSRFGKFIRI+F G + A+IETYLLEKSR Q Sbjct: 220 EDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQ 279 Query: 295 AKDECSFHIFYQLLGGAGEQLKADLLLEPCSH-YRFLTNGPSSSPG-QERELFQETLESL 352 K E S+HIFYQ+L +L LL+ + + F++ G + P ++E T ++ Sbjct: 280 LKAERSYHIFYQILSNKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAV 339 Query: 353 RVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFS 412 +LGF+ +E +++ ++ AV+ +GN+ K+++ +QA A K L L D Sbjct: 340 DILGFTADEKVAIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLTSLNSADLL 399 Query: 413 RALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQGA 471 ++L PR+KVG ++V K QT +Q A+ ALAKA YE++F W+V R+N+ LD + PRQ Sbjct: 400 KSLCYPRVKVGNEFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQ-- 457 Query: 472 SFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFG 531 F+G+LDIAGFEIF NS EQLCIN+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG Sbjct: 458 YFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFG 517 Query: 532 LDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQRPRHLRD 590 +DL CI+LIE+P G+ ++L+EEC FPKATD SF K+ ++ G FQ+P+ + Sbjct: 518 MDLAACIELIEKPM---GIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKG 574 Query: 591 --QADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLE 648 +A FS++HYAG VDY WL KN DPLN+ V L +S + A ++ + Sbjct: 575 KPEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVVGLYQKSAMKTLAFLFSGAQ-----T 629 Query: 649 QVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLE 708 + G G GG+ + F+TV L++E+L++LM L +T+P FVRCI+PN K G +E Sbjct: 630 AEAEGGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAME 689 Query: 709 PRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKM 767 LVL QLRCNGVLEGIRICR+GFP+RIL+ +F+QRY++L +AIP+G F+D K+A EK+ Sbjct: 690 HELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKL 749 Query: 768 IQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQ 827 + ++E+D Y+ G +K+FF+AG+L LEE RD K+ +I QA RG+L R F+K Sbjct: 750 LGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMM 809 Query: 828 QQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQ 887 +++ ++ +Q N A++ ++HW W +L+ K+KPLL+ ++ + +E +K +E + Sbjct: 810 ERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAK 869 Query: 888 SAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEAR 947 + + EL+ ++ L +E+ L Q++AEA+ A+AEE +L K +LE + E+ R Sbjct: 870 TEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTER 929 Query: 948 VGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLL 1007 +EEE + ++ +K++L+ EL+ ++ E K++ EK TE K+K E++ L Sbjct: 930 AEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGL 989 Query: 1008 EDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGR 1067 ++ +KL+KE+K L++ + EE+KV +L K + K E + D+E L +E+K Sbjct: 990 DETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLC 1049 Query: 1068 QELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLL 1127 +LE+ KR+L+G+ QE ++ + ++L +L +KE E+ + EDE QL Sbjct: 1050 MDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQ 1109 Query: 1128 KSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRS 1187 K ++E QA + E +E++E+ER +R KAEKQR DL ELE + LE+ +T+AQ E+ Sbjct: 1110 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169 Query: 1188 KREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALE 1247 KRE E ++++ LEE T HEA LR++H ++ EL EQ++ +R K EK + L+ Sbjct: 1170 KREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELK 1229 Query: 1248 AEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELE 1307 E+++L + + ++ A+ E+ R LE QL E++ + + +R E + + R E Sbjct: 1230 MEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESG 1289 Query: 1308 NVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLRE 1367 S L+E ++ +LS+ + Q+ + + L+EET+AK L +++ + LRE Sbjct: 1290 EFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLRE 1349 Query: 1368 QLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLA 1426 Q EEE A+ R + A +++++WR + E +A E EEA+++ A+ + + + Sbjct: 1350 QYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVE 1409 Query: 1427 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1486 LE+ ++RLQ E++D +D+E+ L+KKQR FD++LAE K Sbjct: 1410 AVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA 1469 Query: 1487 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1546 E E ++ E R + A EE + E L+R+N+ L+ E+ L + GK +HE Sbjct: 1470 ELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHE 1529 Query: 1547 LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEE 1606 LE+ + + ++L+ + E E L E LR+++ + +K++ +R + +DE ++ Sbjct: 1530 LEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQ 1589 Query: 1607 RRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1666 +R + + + D E + R A+ +KK+EG+L E++ Q+ A + EA++ LR Sbjct: 1590 LKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRN 1649 Query: 1667 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQD 1726 Q +K+ +++ ++++ Q E+R ++AEV L+ L ++R R+ A+Q+ Sbjct: 1650 TQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQE 1709 Query: 1727 RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESL 1786 + ++ V + +++ K++LE + Q++ E+E+ + ++ +K + + Sbjct: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMM 1769 Query: 1787 TTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1846 EL E+ SA E ++ +E+ +++L+ RL E + A K I LE+++ + E + Sbjct: 1770 AEELKKEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESE 1829 Query: 1847 LEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1906 +E E + + + K +R+ E+R+KE+ Q EE+R+ +L+D ++K +VK KRQ EEA Sbjct: 1830 VESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEA 1889 Query: 1907 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 EE+++ A R+LQ ELE+ E A+ +V LR + R Sbjct: 1890 EEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSR 1929 Score = 241 bits (615), Expect = 5e-63 Identities = 205/922 (22%), Positives = 421/922 (45%), Gaps = 39/922 (4%) Query: 1038 KVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEE 1097 K+K L LK T +M + + EK ++EL K + + EL+E+MV Q + Sbjct: 839 KIKPL----LKSAETEKEMANMKEEFEKTKEELAKT----EAKRKELEEKMVTLMQEKND 890 Query: 1098 LRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157 L+ Q+ + + L A R + QL+K+ + +A + E E E E + + Sbjct: 891 LQLQVQAEADALADAEERCD-------QLIKTKIQLEAKIKEVTERAEDEEEINAELTAK 943 Query: 1158 RRDLGEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQEL 1214 +R L +E L+ +++D TL ++ + + +TE L+E + L Sbjct: 944 KRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKAL 1003 Query: 1215 RQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRL 1274 ++ H Q L +L Q+E+ + KT+L E +V +L L + + E+ +R+L Sbjct: 1004 QEAHQQTLDDL--QMEEDKVNTLTKAKTKL--EQQVDDLEGSLEQEKKLCMDLERAKRKL 1059 Query: 1275 ELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQL 1334 E L+ Q D E + + EKL++ + E+ N+ G + + ++ I+L K++ +A++ Sbjct: 1060 EGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARI 1119 Query: 1335 HDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWR 1394 + +E ++ E ++ + + E + E+LEE A + +A+ + R Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMR 1179 Query: 1395 RRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLE 1454 R EE EA A R+ ++ +AE E +D L+R +++L++E + M++ Sbjct: 1180 RDLEESTLQHEATAAALRKKHADS------VAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233 Query: 1455 QQRQLVSTLEKKQRKFDQL---LAEEKAAVLRAVEERERAEAEGREREARALS----LTR 1507 + T+ K + F+++ L ++ + + EE++R E ++AR + +R Sbjct: 1234 DLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSR 1293 Query: 1508 ALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTE 1567 L+E+ +L R +A ++E L ++ K+ L A + A + LR Q E Sbjct: 1294 QLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEE 1353 Query: 1568 LEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERK 1627 ++ + + V +T++E D R E EE +++LA++L+DAE + Sbjct: 1354 EQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNS 1413 Query: 1628 QRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREE 1687 + +++L+ E+E+L + + K+ R + E ++ EET+ E Sbjct: 1414 KCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEA 1473 Query: 1688 IFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEE 1747 ++R L ++ + L R + QQ+ ++ +++A G + + Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKV 1533 Query: 1748 KRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQL 1807 K+QL+ +L+ LEE +++ E + ++ L++ + +E+ +R + K E Q Sbjct: 1534 KKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEI--DRKIAEKDEELDQLK 1591 Query: 1808 ERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAE 1865 ++ + DA R+R+ +E L + E QL R+ + + +R + Sbjct: 1592 RNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQ 1651 Query: 1866 KRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELE 1925 LK+ L +++ R D L++QL R ++ ++EE R + GR+ ++EL Sbjct: 1652 GILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELL 1711 Query: 1926 DVTESAESMNREVTTLRNRLRR 1947 D +E + ++ + T+L N ++ Sbjct: 1712 DASERVQLLHTQNTSLINTKKK 1733 Score = 181 bits (458), Expect = 8e-45 Identities = 204/949 (21%), Positives = 411/949 (43%), Gaps = 98/949 (10%) Query: 856 TKVKPLLQVTRQDEV--LQARAQELQKVQELQQQSAREVGELQGRVAQ-------LEEER 906 TK K LQ Q + LQ ++ + + + + ++V +L+G + Q LE + Sbjct: 997 TKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAK 1056 Query: 907 ARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ 966 +L L+ E + E + +L + ++ E +S L+ ++ +E+ + Q+Q + K LQ Sbjct: 1057 RKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQ 1116 Query: 967 QHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLL-----------LLEDQNSKLS 1015 I+ELE +EAE +R K + ++ ++++ E L + + + ++ Sbjct: 1117 ARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQ 1176 Query: 1016 KERKLLEDRLAEFSSQAA-----------EEEEKVKSLNKLRLKYEAT-------IADME 1057 K R+ LE+ + + AA E E++ SL +++ K E I D+ Sbjct: 1177 KMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLA 1236 Query: 1058 DRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAE 1117 + K + EK+ R L+ + SE++ + EQQ+ EL AQ R E + + Sbjct: 1237 SNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLD 1296 Query: 1118 DEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLD 1177 ++ +QL + + + E + LE E A++ + + + LR + E+ + Sbjct: 1297 EKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQE 1356 Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237 + Q SK EV + + E + ++E +++ Q L + E +E Sbjct: 1357 AKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCA 1416 Query: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAE 1297 + EKT+ L+ EV +L ++ A ++++R + L E + + + + A EA++ Sbjct: 1417 SLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQ-AELEASQ 1475 Query: 1298 KLQRA-QAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVR 1356 K R+ EL V A E+ L +E + + ++ D E + E + L + Sbjct: 1476 KESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKK 1535 Query: 1357 AMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE-AGALEAGEEARRRAA 1415 ++ E + L+ LEE A+ E ++ Q +L++ + + + A E ++ +R Sbjct: 1536 QLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHL 1595 Query: 1416 REAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL--------EQQRQLVST----- 1462 R E++ L + + + R +++++ +L++ + L E R L +T Sbjct: 1596 RVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILK 1655 Query: 1463 -----LEKKQRKFDQL-----LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1512 L+ R D L + E +A +++A E RA E ER + + L + Sbjct: 1656 DTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAE--QELLDA 1713 Query: 1513 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1572 E + L QN +L + L + + + ++ + R AE+ A + +EL Sbjct: 1714 SERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEEL 1773 Query: 1573 TAAEDAKLRLEVTVQALKTQHERDLQGR-DEA-------GEERRRQLAKQLRDAEVERDE 1624 +D LE + ++ Q +DLQ R DEA G+++ ++L ++R+ E E + Sbjct: 1774 KKEQDTSAHLERMKKNME-QTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVES 1832 Query: 1625 ERKQRTLAVAARKKLEGELEELKAQ---------------------MASAGQGKEEAVKQ 1663 E+K AV +K E ++EL Q + + + EEA +Q Sbjct: 1833 EQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQ 1892 Query: 1664 LRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712 A+ ++L E+EE + + ++++ ++ R+K E + EE Sbjct: 1893 SNVNLAKFRKLQHELEEAKERAD--IAESQVNKLRVKSREVHTKVISEE 1939 Score = 135 bits (340), Expect = 4e-31 Identities = 170/785 (21%), Positives = 329/785 (41%), Gaps = 120/785 (15%) Query: 1247 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAEL 1306 E E++ ++ E + + E +R+ LE ++ + D Q ++ Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKND--------------LQLQV 895 Query: 1307 ENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLR 1366 + + AL +AE + +L K EA++ + E ++E L ++ R +E E + L+ Sbjct: 896 QAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955 Query: 1367 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALE--AGEEARRRAAREAEALT-Q 1423 + +++ + +E + ++ + EE AG E A ++A +EA T Sbjct: 956 KDIDDLELTLAKVEKEKHATENKV---KNLTEEMAGLDETIAKLTKEKKALQEAHQQTLD 1012 Query: 1424 RLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLR 1483 L + + V+ L + + +L+Q++DD LEQ+++L LE+ +RK + L + + + Sbjct: 1013 DLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMD 1072 Query: 1484 AVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKS 1543 ++++ + +++E +L +E+EQ +L+++ + L+A +E L ++++ Sbjct: 1073 TENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEEL---EEEI--- 1126 Query: 1544 VHELERACRV-AEQAANDLRAQVTELEDELT---AAEDAKLRLEVTVQALKTQHERDLQG 1599 E ERA R AE+ +DL ++ E+ + L A A++ + +A + RDL+ Sbjct: 1127 --EAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE 1184 Query: 1600 RDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE 1659 E L K+ D+ E E Q ++KLE E ELK ++ E Sbjct: 1185 STLQHEATAAALRKKHADSVAELGE---QIDSLQRVKQKLEKEKSELKMEINDLASNMET 1241 Query: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRA 1719 K + + L ++ E +T EE ++ + L A+ RL E S Sbjct: 1242 VSKAKANFEKMCRTLEDQLSEIKTKEEE-------QQRLINELSAQKARLHTE---SGEF 1291 Query: 1720 RRQAQQDRDEMADEVANGNLSKAAILEE-KRQLEGRLGQ-----------------LEEE 1761 RQ + +D M +++ G + +EE KRQLE L E+ Sbjct: 1292 SRQLDE-KDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQ 1350 Query: 1762 LEEEQ------------SNSEL-----------------LNDRYRKLLLQVESLTTELSA 1792 EEEQ +NSE+ L + +KL +++ + A Sbjct: 1351 YEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEA 1410 Query: 1793 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKM------TIAALESKLAQAEEQ 1846 S A E +Q+L+ ++++L + +A A K +A + K + + + Sbjct: 1411 VNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE 1470 Query: 1847 LEQETRE-RILSGKL----------------VRRAEKRLKEVVLQVEEERRVADQLRDQL 1889 LE +E R LS +L ++R K L++ + + E+ + +L Sbjct: 1471 LEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHEL 1530 Query: 1890 EKGNLRV----KQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1945 EK ++ +L+ LEEAE + R+Q EL V + E ++L Sbjct: 1531 EKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQL 1590 Query: 1946 RRGPL 1950 +R L Sbjct: 1591 KRNHL 1595 >gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo sapiens] Length = 1938 Score = 1262 bits (3265), Expect = 0.0 Identities = 713/1882 (37%), Positives = 1119/1882 (59%), Gaps = 42/1882 (2%) Query: 87 RRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146 R L L DQ+ MNPPKF K EDMA +T L+E +VL+NL+ERY + +IYTYSGLFCV +N Sbjct: 68 RMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVN 127 Query: 147 PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206 PYK LP+Y +V YRGKKR E PPH++++++ AY+ ML DR++QSIL TGESGAGKT Sbjct: 128 PYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTV 187 Query: 207 NTKKVIQYLAHVASSPKGRKE--PG-VPGELERQLLQANPILEAFGNAKTVKNDNSSRFG 263 NTK+VIQY A +A + +KE PG + G LE Q++QANP+LEAFGNAKTV+NDNSSRFG Sbjct: 188 NTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFG 247 Query: 264 KFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEP 323 KFIRI+F G + A+IETYLLEKSR Q E S+HIFYQ++ +L DLLL Sbjct: 248 KFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPEL-IDLLLIS 306 Query: 324 CSHYRFLTNGPSSSPGQ-------ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFG 376 + + F P S G+ + E T ++ +LGFS EE + + ++ AV+ +G Sbjct: 307 TNPFDF----PFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYG 362 Query: 377 NIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQA 436 N+ K+++ +QA A K L+GL + + L PR+KVG +YV K Q +Q Sbjct: 363 NMKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQV 422 Query: 437 DFALEALAKATYERLFRWLVLRLNRALD-RSPRQGASFLGILDIAGFEIFQLNSFEQLCI 495 ++ ALAKA YE++F W+V R+N+ LD + PRQ F+G+LDIAGFEIF NS EQLCI Sbjct: 423 TNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQ--YFIGVLDIAGFEIFDFNSLEQLCI 480 Query: 496 NYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLD 555 N+TNEKLQQ FNH MFVLEQEEY++EGI W F+DFG+DL CI+LIE+P G+ ++L+ Sbjct: 481 NFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPM---GIFSILE 537 Query: 556 EECWFPKATDKSFVEKVA-QEQGGHPKFQRPRHLRDQAD--FSVLHYAGKVDYKANEWLM 612 EEC FPKATD SF K+ Q G FQ+P+ + +A+ FS++HYAG VDY WL Sbjct: 538 EECMFPKATDTSFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLD 597 Query: 613 KNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQ 672 KN DPLN+ V L +S+ +L + ++ + G + G GG+ + F+TV Sbjct: 598 KNKDPLNETVVGLYQKSSLKLLSFLFSNYAGA----ETGDSGGSKKGGKKKGSSFQTVSA 653 Query: 673 LYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGF 732 +++E+L++LM L +T+P FVRC++PN K G ++ LV+ QLRCNGVLEGIRICR+GF Sbjct: 654 VFRENLNKLMTNLRSTHPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGF 713 Query: 733 PNRILFQEFRQRYEILTPNAIPKG-FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGV 791 P+RIL+ +F+QRY IL +AIP+G F+D K A EK++ ++++D +R G +K+FF+AG+ Sbjct: 714 PSRILYADFKQRYRILNASAIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGL 773 Query: 792 LAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQW 851 L LEE RD K+ ++ S QA RGYL R F+K +++ ++ +Q N +++ ++HW W Sbjct: 774 LGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFMNVKHWPW 833 Query: 852 WRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAE 911 LF K+KPLL+ ++ + ++ ++ +E +S EL+ ++ L +E+ L Sbjct: 834 MNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQL 893 Query: 912 QLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE 971 Q+++E E +AEE L K LE V EL R+ EEEE + ++ +K+ L+ Sbjct: 894 QVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSS 953 Query: 972 LEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQ 1031 L+ ++ E K++ EK TE K+K E++ LE+ SKL+KE+K L++ + Sbjct: 954 LKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013 Query: 1032 AAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQ 1091 EE+KV L K+ K E D+E L +E+K R +LE+ KR+L+G+ QE +++ Sbjct: 1014 LQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDL 1073 Query: 1092 QQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVAR 1151 + +++ +L +KE EL A+ +DE Q K ++E QA + E +E++E+E R Sbjct: 1074 ENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLR 1133 Query: 1152 TKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAV 1211 K EKQR DL ELE + LE+ +T+AQ E+ KRE E ++++ LEE T HEA Sbjct: 1134 AKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1193 Query: 1212 QELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRR 1271 LR++ ++ EL EQ++ +R K EK + L+ E+ ++ + + +L ++ E+ Sbjct: 1194 ATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTC 1253 Query: 1272 RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELEN--VSGALNEAESKTIRLSKELSS 1329 R +E Q E+ +A D ++ + +Q+A+ + +N +S + E ES +L+K + Sbjct: 1254 RTVEDQFSEI--KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQA 1311 Query: 1330 TEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQ 1389 QL + + ++EET+AK A+ +++ + LREQ EEE A+ R L A ++ Sbjct: 1312 LTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSE 1371 Query: 1390 LSEWRRRQEEEA-GALEAGEEARRRAAREAEALTQRLAEKTETVD----RLERGRRRLQQ 1444 +++WR + E +A E EEA+++ A+ Q E TET + LE+ ++RLQ Sbjct: 1372 VAQWRTKYETDAIQRTEELEEAKKKLAQR----LQEAEENTETANSKCASLEKTKQRLQG 1427 Query: 1445 ELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALS 1504 E++D DLE+ +TL+KKQR FD++LAE K + + E E A+ E R Sbjct: 1428 EVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFK 1487 Query: 1505 LTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1564 + A EE + E L R+N+ L+ E+ L + GK++ E E+ ++ EQ +DL+ Sbjct: 1488 MRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA 1547 Query: 1565 VTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE 1624 + E+E L E LR+++ + +K++ +R + +DE E+ +R + + D Sbjct: 1548 LEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDA 1607 Query: 1625 ERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1684 E + R A+ +KK+EG+L E++ Q+ + + E K LR +Q Q+K+ +++ S Sbjct: 1608 EIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRS 1667 Query: 1685 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAI 1744 E++ Q E+R L E+ ++ L ++R RR ++Q+ + +D V + ++ Sbjct: 1668 NEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSL 1727 Query: 1745 LEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGR 1804 + K++LE + Q + E+E S ++ +K + + EL E+ SA E + Sbjct: 1728 INTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787 Query: 1805 QQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRA 1864 + LE+ +++L+ RL E + A K I LE+++ + E +L+ E + + K + Sbjct: 1788 KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKY 1847 Query: 1865 EKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQREL 1924 E+++KE+ Q EE+ + +L+D ++K +VK KRQ EEAEE+A+ + RR+Q EL Sbjct: 1848 ERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHEL 1907 Query: 1925 EDVTESAESMNREVTTLRNRLR 1946 E+ E A+ +V LR + R Sbjct: 1908 EEAAERADIAESQVNKLRAKSR 1929 Score = 214 bits (546), Expect = 5e-55 Identities = 199/948 (20%), Positives = 429/948 (45%), Gaps = 39/948 (4%) Query: 1044 KLRLKYEATIADMEDRLRKE--EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQ 1101 K++ ++ A+ E KE E+ ++EL + + R EL+E+MV Q +L+ Q Sbjct: 839 KIKPLLKSAEAEKEMATMKEDFERTKEELARSEAR----RKELEEKMVSLLQEKNDLQLQ 894 Query: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1161 + + E L A R E L+KS +A + E E LE E ++ ++R+L Sbjct: 895 VQSETENLMDAEERCEG-------LIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNL 947 Query: 1162 GEELEALRGELED---TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRH 1218 ++ +L+ +++D TL ++ + + ++E LEE + L++ H Sbjct: 948 EDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAH 1007 Query: 1219 GQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQL 1278 Q L +L Q+E+ + K LE + +L L + R + E+ +R+LE L Sbjct: 1008 QQTLDDL--QVEEDK--VNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL 1063 Query: 1279 QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQ 1338 + Q D E + + EKL++ + EL + +++ + +++ K++ +A++ + + Sbjct: 1064 KMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELE 1123 Query: 1339 ELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQE 1398 E ++ E + + + + E + E+LEE + A + +A+ + RR E Sbjct: 1124 EEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLE 1183 Query: 1399 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1458 E EA R+ ++ +AE E +D L+R +++L++E + M+++ Sbjct: 1184 EATLQHEATAATLRKKQADS------VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMAS 1237 Query: 1459 LVSTLEKKQRKFDQLL--AEEKAAVLRAVEERERAEAEGREREARALS-----LTRALEE 1511 + L K + ++ E++ + ++A +E++ + L L+ +EE Sbjct: 1238 NIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEE 1297 Query: 1512 EQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDE 1571 ++ +L + +AL +LE L ++ K+ + + A + + + LR Q E ++ Sbjct: 1298 KESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357 Query: 1572 LTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTL 1631 + A + V +T++E D R E EE +++LA++L++AE + + Sbjct: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417 Query: 1632 AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQ 1691 +++L+GE+E+L + + K+ R + E ++++E++ E + Sbjct: 1418 LEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKE 1477 Query: 1692 NRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQL 1751 +R L + + ++L R + Q++ ++ +++A + + K+ + Sbjct: 1478 SRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLV 1537 Query: 1752 EGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQI 1811 E L+ LEE + + E + ++ L++ + +EL +R K E +QL+R Sbjct: 1538 EQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSEL--DRKVIEKDEE-IEQLKRNS 1594 Query: 1812 QELRGRLGEE-DAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKLVRRAEKRL 1868 Q L DA R+R+ +E L + E QL R+ + K +R + +L Sbjct: 1595 QRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL 1654 Query: 1869 KEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVT 1928 K+ L +++ R + L++QL R L +LEE + + + RR ++EL D + Sbjct: 1655 KDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714 Query: 1929 ESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEA 1976 + + ++ + T+L N ++ ++E ++E+A++A Sbjct: 1715 DRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKA 1762 Score = 139 bits (349), Expect = 4e-32 Identities = 181/852 (21%), Positives = 343/852 (40%), Gaps = 195/852 (22%) Query: 871 LQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRL 930 LQA+ + ++V LQ Q +++ ELQ R+ +LEEE + AE L A+ E+ R L Sbjct: 1094 LQAKIDD-EQVHSLQFQ--KKIKELQARIEELEEE-------IEAEHTLRAKIEKQRSDL 1143 Query: 931 AARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAE----------- 979 A +E+ + E + E +++ + E +++++ ++E EA Sbjct: 1144 ARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADS 1203 Query: 980 -----------EGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1028 + +QKL+ EK + ++ ++ L S + + + +ED+ +E Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEI 1263 Query: 1029 SSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQM 1088 ++ ++ + + LN + + + ++ R+ ++E +L K K+ L + EL+ QM Sbjct: 1264 KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM 1323 Query: 1089 VEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESER 1148 E+ + + L + + E+E A+A+L ++L +A + +A+ + E++ Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDA 1383 Query: 1149 VARTKA-EKQRRDLGEELEA---------------------LRGELEDTLD----STNAQ 1182 + RT+ E+ ++ L + L+ L+GE+ED + S A Sbjct: 1384 IQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTAC 1443 Query: 1183 QELRSKR---EQEVTELKKTLEEETRIHEAAVQELRQ------RHGQALGELAEQLEQAR 1233 L K+ ++ + E K+ L+E EAA +E R + A E+ +QLE R Sbjct: 1444 ATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLR 1503 Query: 1234 R-------------------GKGAWE--KTRLALEAEVSELRAELSSLQTARQEGEQRRR 1272 R GK E KT+ +E E S+L+ L ++ + + E + Sbjct: 1504 RENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKIL 1563 Query: 1273 RLELQLQEVQGRAGDGERARAEAAEKL----QRAQAELENV------------------S 1310 R++L+L +V+ + E E+L QRA L++V Sbjct: 1564 RVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKME 1623 Query: 1311 GALNEAE-------SKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 G LNE E + K L + + QL D+Q L + R+ L ++ +E Sbjct: 1624 GDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNG 1683 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSE-----------------WRRRQEEEAGALEA 1406 L E+LEE A E+ R + ++ +L + +++ E + +A Sbjct: 1684 LLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA 1743 Query: 1407 -----------GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQ 1455 EE ++A +A + + L ++ +T LER ++ L+Q + D L++ Sbjct: 1744 EVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803 Query: 1456 QRQL--------VSTLEKKQRKFDQLL---------------------------AEE--- 1477 QL + LE + R+ + L AEE Sbjct: 1804 AEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHK 1863 Query: 1478 ------------KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRA 1525 +A V + E AE + + +R + LEE E + E Q Sbjct: 1864 NILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNK 1923 Query: 1526 LRAELEALLSSK 1537 LRA+ + S K Sbjct: 1924 LRAKSRDVGSQK 1935 Score = 116 bits (291), Expect = 2e-25 Identities = 142/658 (21%), Positives = 279/658 (42%), Gaps = 46/658 (6%) Query: 853 RLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQ----------QSAREVGELQGRVAQL 902 R+ K + Q+T+ + L + +EL++ E + QS+R +L Q Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE--QY 1351 Query: 903 EEERARLAEQLRAEAELCAEAEETRGRLAA----RKQELELVVSELEARVGEEEECSR-- 956 EEE+ AE RA ++ +E + R + R +ELE +L R+ E EE + Sbjct: 1352 EEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETA 1411 Query: 957 -----QMQTEKKRLQQHIQELEAHLEAEEGA-----RQKLQLEKVTTEAKMKKFEEDLLL 1006 ++ K+RLQ +++L LE A +++ +KV E K K E L Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471 Query: 1007 LEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKG 1066 Q KE + L L + + E +++++L + + I+D+ +++ + K Sbjct: 1472 EAAQ-----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKN 1526 Query: 1067 RQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQL 1126 QE EK K+ ++ E S+LQ + E + E +++ R + EL + + + + + Sbjct: 1527 LQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE 1586 Query: 1127 LKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1186 ++ L+ AEA L+S A ++ L +++E E+E L +N Q Sbjct: 1587 IEQLKRNSQRAAEA---LQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643 Query: 1187 SKREQEVT-ELKKT---LEEETRIHEAAVQELR--QRHGQALGELAEQLEQARRGKGAWE 1240 K + V +LK + L++ R +E ++L +R G L E+LE+ + E Sbjct: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRN---GLLLEELEEMKVALEQTE 1700 Query: 1241 KTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQ 1300 +TR E E+ + + L + +++LE + + Q + + A EK + Sbjct: 1701 RTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAK 1760 Query: 1301 RAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR-VRAME 1359 +A + ++ L + + + L + + E + D Q L E + L G + ++ +E Sbjct: 1761 KAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820 Query: 1360 AEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAE 1419 L +L+ E A + + ++ E + EE+ + ++ + + + Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880 Query: 1420 ALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477 + ++ E E + RR+Q EL++A + V+ L K R EE Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 1155 bits (2989), Expect = 0.0 Identities = 682/1909 (35%), Positives = 1077/1909 (56%), Gaps = 37/1909 (1%) Query: 53 RRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAE 112 ++ W+P + + A ++ ++ + G L + D+IQ+MNPP+F EDMA Sbjct: 51 KKKCWIPDGENAYIEAEVKGSEDDGTVIVETADGESLSIKEDKIQQMNPPEFEMIEDMAM 110 Query: 113 LTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKRHEVPP 172 LT LNEASVLH L+ RY +IYTYSGLFCV INPYK LP+Y + ++ Y+GK+R E PP Sbjct: 111 LTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSEAPP 170 Query: 173 HVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKEPGVPG 232 H++AV A++ ML +RE+QSIL TGESGAGKT N+K +IQY A +A+ + RK+ G Sbjct: 171 HIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQGA-- 228 Query: 233 ELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAI 292 LE Q++QAN ILEAFGNAKT++NDNSSRFGKFIR++F G + +I+ YLLEKSR I Sbjct: 229 -LEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287 Query: 293 RQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPG-QERELFQETLES 351 Q E ++HIFYQ+L G E L+ S + F + G + + E T ++ Sbjct: 288 FQQAGERNYHIFYQILSGQKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELLATEQA 347 Query: 352 LRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDF 411 + +LGF +E ++ A++ FGN+ K++ +Q A K L+G+ ++ Sbjct: 348 MDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGTENADKAAFLMGINSSEL 407 Query: 412 SRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD-RSPRQG 470 + L+ PRIKVG +YV + QT EQ A+ AL+K+ YER+F+WLV R+NRALD + RQ Sbjct: 408 VKCLIHPRIKVGNEYVTRGQTIEQVTCAVGALSKSMYERMFKWLVARINRALDAKLSRQ- 466 Query: 471 ASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDF 530 F+GILDI GFEI + NS EQLCIN+TNEKLQQ FN MFVLEQEEY++E I W + F Sbjct: 467 -FFIGILDITGFEILEYNSLEQLCINFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGF 525 Query: 531 GLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGG---HPKFQRPRH 587 GLDLQ CIDLIE+P G+L++L+EEC FPKATD +F K+ G H + +P Sbjct: 526 GLDLQACIDLIEKPM---GILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDK 582 Query: 588 LRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEGIVGL 647 + +A F ++HYAG V Y + WL KN D LN+ V A+ +S++RL A ++ Sbjct: 583 KKFEAHFELVHYAGVVPYNISGWLEKNKDLLNETVVAVFQKSSNRLLASLF--------- 633 Query: 648 EQVSSLGDGPPGGRPRR---GMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRA 704 E S P G +R F+TV L+KE+L++LM L +T P FVRCI PN K Sbjct: 634 ENYMSTDSAIPFGEKKRKKGASFQTVASLHKENLNKLMTNLKSTAPHFVRCINPNVNKIP 693 Query: 705 GKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG-FMDGKQA 763 G L+P LVL QLRCNGVLEG RICR+GFPNR+ + +F+QRY IL P PK F+ ++A Sbjct: 694 GILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFPKSKFVSSRKA 753 Query: 764 CEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAF 823 E+++ +LE+D YR G +K+FF+AG L QLE RD +++ + FQA A+G L R F Sbjct: 754 AEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFTLFQARAQGKLMRIKF 813 Query: 824 QKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQE 883 QK +++ AL ++Q N A++ +++W W RLF K+KPL++ + E + +E ++Q+ Sbjct: 814 QKILEERDALILIQWNIRAFMAVKNWPWMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQK 873 Query: 884 LQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSE 943 ++S + EL+ + L +E+ L QL+AE E A EE L K +LE V E Sbjct: 874 ALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKE 933 Query: 944 LEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEED 1003 L RV EEEE + ++ ++L+ EL+ ++ E K + EK TTE K+K E+ Sbjct: 934 LSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEE 993 Query: 1004 LLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE 1063 + L + SKL++ K++++ + EEEK+ SL+K LK E + ++E L +E Sbjct: 994 VEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQE 1053 Query: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 K R E+ +L+G +E M + L +L +KE EL ++ E+E G Sbjct: 1054 RKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLV 1113 Query: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183 AQL K+++E Q + + +E LE+ER R K E++R DL ++L L LE+ S+ AQ Sbjct: 1114 AQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQL 1173 Query: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 E+ K+E + +L + +EE T E L++RH +L EL Q+E ++ K EK + Sbjct: 1174 EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDK 1233 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 L+ EV +L + + A+ E+ E +L E + + + A + + Sbjct: 1234 SDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLW 1293 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 +E L E E+ +LS+E S+ Q+ D + L++ET+++ AL ++ + + Sbjct: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCD 1353 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEA-GALEAGEEARRRAAREAEALT 1422 LREQ EEE + R L A++ +WR + E E E+A++ A + Sbjct: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAA 1413 Query: 1423 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482 + + LER R +LQ EL DA DL + R + L++KQ + + LA+ K Sbjct: 1414 EAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQK-- 1471 Query: 1483 RAVEERERAEAEGREREARALS-----LTRALEEEQEAREELERQNRALRAELEALLSSK 1537 E +A + ++E +ALS L EE +E L R+N+ L+ E+ L + Sbjct: 1472 ---HEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQV 1528 Query: 1538 DDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDL 1597 + K++ E+E+ ++ E+ +++ + E E L E L ++ + K + ER L Sbjct: 1529 REGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKL 1588 Query: 1598 QGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGK 1657 +DE E RR+ + + D E K R +KK+E +L E++ Q++ A + Sbjct: 1589 SEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQV 1648 Query: 1658 EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASD 1717 EA K L ++Q Q+K+L +++++ ++ Q +E+R L++E+ L+ ++ Sbjct: 1649 SEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTE 1708 Query: 1718 RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYR 1777 R RR ++++ E + + ++L +K++LE + ++++E EE + ++ + Sbjct: 1709 RGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAK 1768 Query: 1778 KLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALE 1837 K ++ +L+ EL ++ A E R+ +E+ I +L+ RL E + A + I LE Sbjct: 1769 KAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLE 1828 Query: 1838 SKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVK 1897 S++ + E +LE E R + + RR E+ +KE+ Q EE+++ +++ Q++K L+V+ Sbjct: 1829 SRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQ 1888 Query: 1898 QLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLR 1946 K+Q+E AE +A++ + ++ Q EL +V E AE +V L+ + R Sbjct: 1889 NYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQVNKLKIKAR 1937 Score = 189 bits (479), Expect = 3e-47 Identities = 224/1015 (22%), Positives = 441/1015 (43%), Gaps = 59/1015 (5%) Query: 987 QLEKVTTEAKMKKFEEDLLLLEDQNSKLS--KERKLLEDRLAEFSSQ-AAEEEEKVKSLN 1043 QLE + E K F L KL K +K+LE+R A Q VK+ Sbjct: 784 QLEAIRDERLSKVFT---LFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWP 840 Query: 1044 KLRLKYEATIADMEDRLRKEEKGRQE----LEKLKRRLDGESSELQEQMVEQQQRAEELR 1099 +RL ++ + +E G +E L+K + + + EL+ + V Q +L Sbjct: 841 WMRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLI 900 Query: 1100 AQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1159 QL ++E L + E L+KS + +A + E E +E E ++ + R Sbjct: 901 LQLQAEQETLANVEEQCE-------WLIKSKIQLEARVKELSERVEEEEEINSELTARGR 953 Query: 1160 DLGEELEALRGELEDT---LDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1216 L +E L+ E++D L + ++ + + +TE + L E+ A + +++ Sbjct: 954 KLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQE 1013 Query: 1217 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1276 H Q L +L + E+ + K L LE +V EL L + AR E+ +LE Sbjct: 1014 AHQQTLDDLHMEEEKL----SSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEG 1069 Query: 1277 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1336 L+ + + E ++ AE+L++ + EL ++ + + +L K + + Q+ D Sbjct: 1070 NLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKD 1129 Query: 1337 AQELLQEE--TRAKLALGSRVRA-MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEW 1393 +E L+ E TRAK+ R RA + + A L E+LEE + + + + + Sbjct: 1130 LKEKLEAERTTRAKM---ERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKL 1186 Query: 1394 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETV-DRLERGRRRLQQELDDATMD 1452 R EE E + ++ ++ A + E + V +LE+ + LQ E+DD Sbjct: 1187 HRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTR 1246 Query: 1453 LEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEE 1512 +EQ + + EK +++ L E A + + + A+ + + + R LEE+ Sbjct: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEK 1306 Query: 1513 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1572 + +L R+ ++E L + KS L A + A++ + LR Q E ++ Sbjct: 1307 EALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK 1366 Query: 1573 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632 ++ + + ++E ++ R E E+ +++LA +L++A + Sbjct: 1367 AELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASL 1426 Query: 1633 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN 1692 AR +L+ EL + + + A +L + Q Q + + + + EE + Sbjct: 1427 ERARHQLQLELGDALSDLGKV----RSAAARLDQKQLQSG---KALADWKQKHEESQALL 1479 Query: 1693 RESEKRLKGLEAEVLRL----QEELAASDRARRQ---AQQDRDEMADEVANGNLSKAAIL 1745 S+K ++ L E+L+L +E + + RR+ Q++ + ++V G + + Sbjct: 1480 DASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEME 1539 Query: 1746 EEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK---AES 1802 + K+ +E +++ LEE + E + + L Q+E L + ER S K E+ Sbjct: 1540 KVKKLIEEEKTEVQVTLEETEGALE--RNESKILHFQLELLEAKAELERKLSEKDEEIEN 1597 Query: 1803 GRQQLERQIQELRGRLGEEDAGARARHKMTIAA--LESKLAQAEEQLEQETRERILSGKL 1860 R++ + I L+ L D+ A++R ++T +E L + E QL R+ + K Sbjct: 1598 FRRKQQCTIDSLQSSL---DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKS 1654 Query: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920 + + + ++K++ +Q+++ ++ L++Q+ R L+ +LE+ + + GRR Sbjct: 1655 LGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLS 1714 Query: 1921 QRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975 + EL + TE + T+L ++ ++ R EE V + AEE Sbjct: 1715 EEELLEATERINLFYTQNTSLLSQKKK----LEADVARMQKEAEEVVQECQNAEE 1765 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 558 bits (1439), Expect = e-158 Identities = 452/1509 (29%), Positives = 732/1509 (48%), Gaps = 145/1509 (9%) Query: 56 VWVPSELHGFEAAALRD---EGEEEAEVELAESGRRLRLPRDQIQR------MNPPKFSK 106 VW+P + +A L EG++ ++ L E L P D +QR NP Sbjct: 13 VWIPDPDEVWRSAELTKDYKEGDKSLQLRL-EDETILEYPID-VQRNQLPFLRNPDILVG 70 Query: 107 AEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGK 165 D+ L+ L+E +VLHNL+ R+ S IYTY G+ V INPY+QLPIY + ++ Y G+ Sbjct: 71 ENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQ 130 Query: 166 KRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGR 225 ++ PH++AV E AY+ M +D ++QSI+ +GESGAGKT + K ++Y A V S Sbjct: 131 NMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASET 190 Query: 226 KEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYL 285 +E ++L ++PI+EA GNAKT +NDNSSRFGK+I+I FD +I+GAN+ TYL Sbjct: 191 N-------IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYL 243 Query: 286 LEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSS--PGQERE 343 LEKSR + QA DE ++HIFYQL AG +L L + + + G +S + E Sbjct: 244 LEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAE 303 Query: 344 LFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATM-PDNTAAQKLCR 402 F++T ++ +LG +S+ ++++++L G++A++ ER+ D ++ P + CR Sbjct: 304 DFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCR 363 Query: 403 LLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRA 462 LLG+ + L ++ + K + +Q A ALAK Y +LF W+V +N+A Sbjct: 364 LLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKA 423 Query: 463 LDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREG 522 L S +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E Sbjct: 424 LHTSLKQ-HSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQ 482 Query: 523 IPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKF 582 IPWT +DF D QPCIDLIE G+L LLDEEC PK TD+++ +K+ F Sbjct: 483 IPWTLIDF-YDNQPCIDLIEAKL---GILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHF 538 Query: 583 QRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD-- 640 Q+PR F ++H+A KV+Y ++ +L KN D + + +L S L A+++ D Sbjct: 539 QKPR--MSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDK 596 Query: 641 ------VEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVR 694 G ++S PP + +TVG ++ SL LM TL+ T P +VR Sbjct: 597 DPVPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVR 656 Query: 695 CIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIP 754 CI PN EK +P+ + QLR GVLE IRI G+P+R + +F RY +L Sbjct: 657 CIKPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKR-E 715 Query: 755 KGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 814 D K C +++ L DP+ ++ G++KIFFRAG +A LE+ R K + Q Sbjct: 716 LANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTV 775 Query: 815 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLR-------------HWQWWRLFTKVKPL 861 RG+L + K + + A +QR C +L R + +R+ + Sbjct: 776 RGWLQK---VKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAY 832 Query: 862 LQVTRQDEVLQA--RAQELQKV--QELQQQSAREVGE-LQGRVAQLEEERARLA------ 910 +V R V+QA RA +++ Q L + A + + ++G +A+ +R R A Sbjct: 833 QRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQC 892 Query: 911 --EQLRAEAELCAEAEETRG--RLAARKQELELVVSELEARVGEEEE----CSRQMQTEK 962 L+A EL A E R L +E V +L+ ++ E+ + S Q+ Sbjct: 893 AFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTT 952 Query: 963 KRLQQHIQELEAHL-----EAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1017 ++ L+ L E +LQ E + ++++ + +LED + S+E Sbjct: 953 STYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAH---SRE 1009 Query: 1018 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRL 1077 + L R+A+ + A +++ + LN L + KE ++ELE+ + R Sbjct: 1010 KDELRKRVADLEQENALLKDEKEQLNNQILCQSKD--EFAQNSVKENLMKKELEEERSRY 1067 Query: 1078 DGESSELQEQMVEQQQRAEELRAQL--------GRKEEELQAALARAEDEGGARAQLLKS 1129 L ++ + +QR + LR ++ R+ Q++L E + + Sbjct: 1068 ----QNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSL---ESDSNYPSISTSE 1120 Query: 1130 LREAQAALAEAQE-DLESERVART---KAEKQRRDLGEELEALRGELE--DTLDSTNAQQ 1183 + + + AL + +E LE + T K +K+ R+L +E + L+ +LE + DS Q Sbjct: 1121 IGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQA 1180 Query: 1184 E-------LRSKREQEVTELKK-TLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRG 1235 E L + LK+ LE E + + + ELR+ +A+Q Q Sbjct: 1181 EPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRK-------AVADQATQNNSS 1233 Query: 1236 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEA 1295 G+ + L L+ L+ A +E E R+ E+ + Q + D R Sbjct: 1234 HGSPDSYSLL-----------LNQLKLAHEELEVRKE--EVLILRTQIVSADQRRLAGRN 1280 Query: 1296 AEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRV 1355 AE A++ N +++ ++ I + T ++ D L ++ LG Sbjct: 1281 AEPNINARSSWPNSEKHVDQEDA--IEAYHGVCQTNSKTEDWGYLNEDG-----ELGLAY 1333 Query: 1356 RAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE---EAGALEAGEEARR 1412 + ++ A L QL+ ++ E L+ L E +Q++ + L + Sbjct: 1334 QGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEF 1393 Query: 1413 RAAREAEALTQRLAEKTETVDRLERGRRRLQQELD---DATMDLEQQRQLVSTLEKKQRK 1469 +E LT + E V++LE+ R+L+++L DLE + L + K+ Sbjct: 1394 GVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSERKRHEL 1453 Query: 1470 FDQLLAEEK 1478 Q+ + K Sbjct: 1454 NRQVTVQRK 1462 Score = 53.1 bits (126), Expect = 3e-06 Identities = 125/604 (20%), Positives = 236/604 (39%), Gaps = 73/604 (12%) Query: 1333 QLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSE 1392 ++ A++ Q RA + + + RAM + +E +A T Q + Sbjct: 824 RMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKAT----------TIQKHVRG 873 Query: 1393 WRRRQE----EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDD 1448 W R+ +A + +A RE +AL A E + RL G ++ ++ Sbjct: 874 WMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIE-ARSAEHLKRLNVG---MENKVVQ 929 Query: 1449 ATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA 1508 +++Q + TL ++ L+ + VE ++ ++ SL R Sbjct: 930 LQRKIDEQNKEFKTLSEQ-------LSVTTSTYTMEVERLKKELVHYQQSPGEDTSL-RL 981 Query: 1509 LEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL 1568 EE + R EL+R + + +A KD++ K V +LE+ + + L Q+ Sbjct: 982 QEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQLNNQI--- 1038 Query: 1569 EDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQ 1628 L ++D + V +K + E + R + L K+ E D R + Sbjct: 1039 ---LCQSKDEFAQNSVKENLMKKELEEE--------RSRYQNLVKEYSQLEQRYDNLRDE 1087 Query: 1629 RTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEI 1688 T+ K+ G Q + ++ ++ ++VEE + + Sbjct: 1088 MTII----KQTPGHRRNPSNQSSLESDSNYPSISTSEI--GDTEDALQQVEEIGLEKAAM 1141 Query: 1689 -FSQNRESEKRLKGLEAEVLRLQ---EELAASDRARRQAQQ-----DRDEMADEVANGNL 1739 + + +KR++ LE E +LQ E+ D + QA+ D D AD +A +L Sbjct: 1142 DMTVFLKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNAD-LAYNSL 1200 Query: 1740 SKAAILEEKRQLEGRLGQLEEELEEE--QSNSELLN-DRYRKLLLQVESLTTELSAERSF 1796 + + E ++L+ L +L + + ++ Q+NS + D Y LL Q++ EL + Sbjct: 1201 KRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEE 1260 Query: 1797 SAKAESGRQQLERQIQELRGRLGEEDAGARA------RHKMTIAALESKLAQAEEQLEQE 1850 + Q + + L GR E + AR+ +H A+E+ + + E Sbjct: 1261 VLILRT--QIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTE 1318 Query: 1851 TRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEA 1910 + + A + LK+V R + QL+ Q + V+ LK QLE +EE Sbjct: 1319 DWGYLNEDGELGLAYQGLKQVA------RLLEAQLQAQSLEHEEEVEHLKAQLEALKEEM 1372 Query: 1911 SRAQ 1914 + Q Sbjct: 1373 DKQQ 1376 Score = 47.8 bits (112), Expect = 1e-04 Identities = 120/610 (19%), Positives = 230/610 (37%), Gaps = 89/610 (14%) Query: 1065 KGRQELEKLKRRLDGESSE-LQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123 K R+EL+ L R++ S+E L+ V + + +L+ ++ + +E + Sbjct: 898 KARRELKAL--RIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKT------------ 943 Query: 1124 AQLLKSLREAQAALAEAQEDLESERV--ARTKAEKQRRDLGEELEALRGELEDTLDSTNA 1181 L + L + E L+ E V ++ E L EE+E+LR EL+ Sbjct: 944 --LSEQLSVTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKI 1001 Query: 1182 QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEK 1241 ++ S+ + E+ + LE+E + + E Q + Q L + ++ Q + +K Sbjct: 1002 LEDAHSREKDELRKRVADLEQENALLK---DEKEQLNNQILCQSKDEFAQNSVKENLMKK 1058 Query: 1242 TRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1301 E+ E R+ +L + EQR L ++ ++ G Sbjct: 1059 -------ELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNP---------- 1101 Query: 1302 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK----LALGSRVRA 1357 N S +++ +I S E+ TE L +E+ E+ L L RVR Sbjct: 1102 -----SNQSSLESDSNYPSISTS-EIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRE 1155 Query: 1358 MEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1417 +E E L+ QLE+ R ++ + QA+ + + A L R+ E Sbjct: 1156 LEQERKKLQVQLEK------REQQDSKKVQAEPPQTDIDLDPNAD-LAYNSLKRQELESE 1208 Query: 1418 AEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEE 1477 + L L E + V D ++ L Q + LE ++ + L + Sbjct: 1209 NKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQI 1268 Query: 1478 KAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA----L 1533 +A ++ R E A S E+ + + +E + + + Sbjct: 1269 VSA------DQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGY 1322 Query: 1534 LSSKDDVGKSVHELERACRVAE-----------QAANDLRAQVTELEDELTAAEDA---- 1578 L+ ++G + L++ R+ E + L+AQ+ L++E+ + Sbjct: 1323 LNEDGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQT 1382 Query: 1579 -----KLRLEVTVQ---ALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRT 1630 + ++E VQ + T DL+ E E+ R+L KQL+ + + + Sbjct: 1383 LLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQA 1442 Query: 1631 LAVAARKKLE 1640 LA + RK+ E Sbjct: 1443 LAQSERKRHE 1452 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 550 bits (1417), Expect = e-156 Identities = 436/1406 (31%), Positives = 688/1406 (48%), Gaps = 125/1406 (8%) Query: 50 WTARRLVWVPSELHGFEAAALRDE---GEEEAEVELAESGRRLRL---PRDQIQRMNPPK 103 +T VW+P +++A + + G++ + L E G L P NP Sbjct: 7 YTQYNRVWIPDPEEVWKSAEIAKDYRVGDKVLRL-LLEDGTELDYSVNPESLPPLRNPDI 65 Query: 104 FSKAEDMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMY 162 D+ L+ L+E +VLHNLR R+ S LIYTYSG+ V +NPYKQLPIY +AI+ Y Sbjct: 66 LVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAY 125 Query: 163 RGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSP 222 G+ ++ PH++AV E AY+ M ++ +QSI+ +GESGAGKT + + ++Y A V+ S Sbjct: 126 SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKS- 184 Query: 223 KGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIE 282 G +E ++L +NPI EA GNAKT +NDNSSRFGK+ I+FD I+GAN+ Sbjct: 185 ------GSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMS 238 Query: 283 TYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--SPGQ 340 TYLLEKSR + Q+++E ++HIFYQL A + L L + + G ++ Sbjct: 239 TYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVN 298 Query: 341 ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKL 400 +R ET ++ +LGF + + + ++++A+L GN+ + N + D++ + Sbjct: 299 DRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVF 358 Query: 401 CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLN 460 C LLGL ++ L +I + V K T+ QA A +ALAK Y LF ++V R+N Sbjct: 359 CELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERIN 418 Query: 461 RALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQR 520 +AL S +Q +F+G+LDI GFE F +NSFEQ CINY NEKLQQ FN +F LEQEEY + Sbjct: 419 QALQFSGKQ-HTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMK 477 Query: 521 EGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQE-QGGH 579 E IPWT +DF D QP IDLIE G+L LLDEEC P TD+++++K+ + Sbjct: 478 EDIPWTLIDF-YDNQPVIDLIEAKM---GILELLDEECLLPHGTDENWLQKLYNNFVNRN 533 Query: 580 PKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWK 639 P F++PR F + H+A KV+YK +L KN D + D + +L S L A ++ Sbjct: 534 PLFEKPR--MSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQ 591 Query: 640 DVEGIVG-LEQVSSLGDGPPGGRPRRGMFR-TVGQLYKESLSRLMATLSNTNPSFVRCIV 697 + + ++ +P FR TVG ++ SL LM TL+ T P +VRCI Sbjct: 592 ENPTPPSPFGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIK 651 Query: 698 PNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGF 757 PN EK + + + ++ QLR GVLE IRI Q +P+R + EF RY IL F Sbjct: 652 PNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQ-ELSF 710 Query: 758 MDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGY 817 D K+ C+ ++ L D N Y+ G++KIFFRAG +A LE+ R K+ V Q RG+ Sbjct: 711 SDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGW 770 Query: 818 LARRAFQKRQQ-----------QQS--------------ALRVMQRNCAAYLKLRHWQWW 852 L R+ F + ++ QQ+ A ++Q++C YL +Q Sbjct: 771 LQRKKFLRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLI 830 Query: 853 RLFTKV-----KPLLQVTRQDEVLQA-RAQELQKVQE---------------LQQQSARE 891 R+ T + L R ++L+ +A LQK L Q Sbjct: 831 RMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYR 890 Query: 892 VGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEE 951 V LQ ++ +E L E+L + A L A E +K E EL + R EE Sbjct: 891 VQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVE-----KIQKLEAELEKAATHRRNYEE 945 Query: 952 EECSRQMQTEKK--RLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1009 + + E+K +LQ+H ELE E + +L+L++ T E K +K + L D Sbjct: 946 KGKRYRDAVEEKLAKLQKHNSELETQKE-----QIQLKLQEKTEELK-EKMDNLTKQLFD 999 Query: 1010 QNSKLSKERKLLED----RLAEFSSQAAEEEEKVKSLNKLRLKYEATIAD---MEDRLRK 1062 K ++R LLE + ++ Q +E++K+L +++ + + D L+ Sbjct: 1000 DVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKA 1059 Query: 1063 EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGA 1122 E + K + E LQ Q ++ ++ + + ++ K E+ L + D Sbjct: 1060 EVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDV 1119 Query: 1123 RAQL----LKSLREAQAALAEAQEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLD 1177 R++L L+ L E L A E L ++ RV + + Q+ +E+EAL ++ Sbjct: 1120 RSRLSVEDLEHLNE-DGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHL-- 1176 Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ--RHGQALGELAEQLEQARRG 1235 QE+ L+K EE I+E+ E+ + + + +Q+ + + Sbjct: 1177 ------------SQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQ 1224 Query: 1236 KGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ-EVQGRAGDGERARAE 1294 K E RL +AE + + E S Q R + E+ +R L+ Q E+ + + + Sbjct: 1225 KQDLE-IRLNEQAEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIH------TKEKEK 1277 Query: 1295 AAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1354 +K+Q Q +++ +E S + D +E L + R L + Sbjct: 1278 LIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQ 1337 Query: 1355 VRAMEAEAAGLREQLEEEAAARERAG 1380 V+ + ++ G + + +E G Sbjct: 1338 VKTL-SKTIGKANDVHSSSGPKEYLG 1362 Score = 70.1 bits (170), Expect = 2e-11 Identities = 120/522 (22%), Positives = 222/522 (42%), Gaps = 74/522 (14%) Query: 1467 QRKFDQLLAEEKAAVLRAVEER--ERAEAEGREREARALSLTRALEEEQEAREELERQNR 1524 +R++ ++L E KA +L+ R + R + LT + Q +++LE QN+ Sbjct: 847 RRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRV---QRLQKKLEDQNK 903 Query: 1525 ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV 1584 +E L S V ++++ E+AA R + + A E+ +L+ Sbjct: 904 ENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQK 963 Query: 1585 TVQALKTQHER---DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAA------ 1635 L+TQ E+ LQ + E +E+ L KQL D +V+++E +QR L + Sbjct: 964 HNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFD-DVQKEE--RQRMLLEKSFELKTQ 1020 Query: 1636 --RKKLEGELEELKAQMASAGQ-------------GKEEAVKQLRKMQAQMKELWREVEE 1680 K+++ EE+KA Q G + V +L K + E +E+E Sbjct: 1021 DYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080 Query: 1681 TRTSR----EEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE--- 1733 + + + + SQ RE +++ + ++L E D R + +D + + ++ Sbjct: 1081 LQAQKIDVEKHVQSQKREMREKMSEITKQLL---ESYDIEDVRSRLSVEDLEHLNEDGEL 1137 Query: 1734 -VANGNLSKAA-ILE------------EKRQLEGRLGQLEEELEEEQSNSELLNDRYRKL 1779 A L KA +LE E L ++ L +E+ Q ND + Sbjct: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197 Query: 1780 LLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESK 1839 +V LT+E F + +LE+Q Q+L RL E+ + K + L ++ Sbjct: 1198 RHEVTRLTSENMMIPDFKQQI----SELEKQKQDLEIRLNEQ----AEKMKGKLEELSNQ 1249 Query: 1840 LAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQL 1899 L +++E+ E R+ + + + EK ++++ +++E + +D L+ Q E + VK Sbjct: 1250 LHRSQEE-EGTQRKALEAQNEIHTKEK--EKLIDKIQEMQEASDHLKKQFETES-EVKCN 1305 Query: 1900 KRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTL 1941 RQ EASR R L+ EL+ + + +V TL Sbjct: 1306 FRQ------EASRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341 Score = 67.0 bits (162), Expect = 2e-10 Identities = 109/511 (21%), Positives = 210/511 (41%), Gaps = 57/511 (11%) Query: 1091 QQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1150 Q R L QL + + LQ L E + L SL +A E + LE+E Sbjct: 876 QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAEL-- 933 Query: 1151 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1210 KA RR+ E+ + R +E+ L Q+ S+ E + +++ L+E+T Sbjct: 934 -EKAATHRRNYEEKGKRYRDAVEEKLAKL---QKHNSELETQKEQIQLKLQEKT------ 983 Query: 1211 VQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQR 1270 +EL+++ +L + +++ R + EK+ E + + ++ SL+ + + Sbjct: 984 -EELKEKMDNLTKQLFDDVQKEERQRMLLEKS---FELKTQDYEKQIQSLKEEIKALKDE 1039 Query: 1271 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330 + +L+ L E + DG +A K + +E E KE+ Sbjct: 1040 KMQLQ-HLVEGEHVTSDGLKAEVARLSKQVKTISEFE-----------------KEIELL 1081 Query: 1331 EAQLHDAQELLQE---ETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1387 +AQ D ++ +Q E R K++ ++ + +R +L E EL A Sbjct: 1082 QAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141 Query: 1388 AQLSEWRRRQEEEAGALEAGEEARRRA-AREAEALTQRLAEKTETVDRLERGRRRLQQEL 1446 L + R LE+ ++++ +E EAL ++ ++ ++ L++ L +E Sbjct: 1142 EGLKKATR-------VLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQK----LFREE 1190 Query: 1447 DDATMDLEQQRQLVSTLEKKQRKFDQLLAE-EKAAVLRAVEERERAEAEGREREARALSL 1505 +D + + +++ F Q ++E EK + E+AE + E + L Sbjct: 1191 NDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQL 1250 Query: 1506 TRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA-------EQAA 1558 R+ EEE R+ LE QN E E L+ ++ ++ L++ Q A Sbjct: 1251 HRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310 Query: 1559 NDLRAQVTELEDELTAAEDAKLRLEVTVQAL 1589 + L + +LE+EL + +L+ V+ L Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTL 1341 Score = 57.0 bits (136), Expect = 2e-07 Identities = 71/351 (20%), Positives = 160/351 (45%), Gaps = 25/351 (7%) Query: 863 QVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAE 922 Q+ E ++A E ++Q L + L+ VA+L ++ ++E + L A+ Sbjct: 1025 QIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQ 1084 Query: 923 AEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQ----QHIQELEAHLEA 978 + + ++K+E+ +SE+ ++ E S ++ + RL +H+ E A Sbjct: 1085 KIDVEKHVQSQKREMREKMSEITKQLLE----SYDIEDVRSRLSVEDLEHLNEDGELWFA 1140 Query: 979 EEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAE---FSSQAAEE 1035 EG ++ ++ + +++ +E+++ L + LS+E L+ E + E Sbjct: 1141 YEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIRHE 1200 Query: 1036 EEKVKSLNKLRLKYEATIADMEDRLRKEE-KGRQELEKLKRRLDGESSELQEQMVEQ--Q 1092 ++ S N + ++ I+++E + + E + ++ EK+K +L+ S++L E+ Q Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEGTQ 1260 Query: 1093 QRAEELRAQLGRKE--------EELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144 ++A E + ++ KE +E+Q A + + +++ + R+ + L DL Sbjct: 1261 RKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDL 1320 Query: 1145 ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ---ELRSKREQE 1192 E E + + K+ +D + L G+ D S+ ++ L+ KRE E Sbjct: 1321 EEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKREDE 1371 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 545 bits (1403), Expect = e-154 Identities = 461/1469 (31%), Positives = 720/1469 (49%), Gaps = 114/1469 (7%) Query: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108 VW+P +++A L + + +V L E G+ L D + NP Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72 Query: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167 D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+ Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132 Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227 ++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188 Query: 228 PGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287 +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE Sbjct: 189 ---EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245 Query: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSSPGQERELF 345 KSR + QA++E ++HIFYQL A L L ++ + G P + + Sbjct: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKL-CRLL 404 T ++ +LG S + + R+++ +L GN+ R+ D T+P + C L+ Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364 Query: 405 GLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD 464 G+ + L ++ + K +K QA A +ALAK Y +LF W+V +N+AL Sbjct: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424 Query: 465 RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524 + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E IP Sbjct: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483 Query: 525 WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQ 583 WT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+ F+ Sbjct: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539 Query: 584 RPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG 643 +PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++ E+++D E Sbjct: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597 Query: 644 IVGLEQVSSLG--------DGPPGGRP---RRGMFRTVGQLYKESLSRLMATLSNTNPSF 692 + +S G P GRP + +TVG ++ SL LM TL+ T P + Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657 Query: 693 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA 752 VRCI PN K + + + QLR GVLE IRI GFP+R +QEF RY +L Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716 Query: 753 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA 812 D KQ C+ +++ L LD + Y+ G++KIFFRAG +A LE+ R K+ + Q Sbjct: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775 Query: 813 AARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQ 872 RG+L R+ K + + A MQR Y + R + + TK ++Q + V++ Sbjct: 776 TIRGWLLRK---KYLRMRKAAITMQRYVRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR 831 Query: 873 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAA 932 R ++++ + QS L+G +A R R + LR + + + RG LA Sbjct: 832 -RRYKIRRAATIVLQS-----YLRGFLA-----RNRYRKILREHKAVIIQ-KRVRGWLAR 879 Query: 933 R--KQELELVVSELEARVGEEEECSRQM--QTEKKRLQQHIQELEAHLEAEEGARQK-LQ 987 K+ + ++ + C R+M + E K+L+ + +E + + G K +Q Sbjct: 880 THYKRSMHAII--------YLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931 Query: 988 LEKVTTEAK--MKKFEEDLLLLED-QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1044 L++ E K E L LE NS+ K R LE RL Q +EEE KV + Sbjct: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLE-RL-----QLSEEEAKVATGRV 985 Query: 1045 LRLKYE-ATIADMEDRLRKEEKGRQE-LEKLKRRLDGESSELQEQMVEQQQRAEELRAQL 1102 L L+ E A + ++ R E+K +E ++ K+ + S L+E+ +Q E L ++ Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045 Query: 1103 GRKEEELQAALARAEDEGGARAQL--------LKSLREAQAALAEAQEDLESERVARTKA 1154 ++ +E+ + + E + +L ++L + L E +DL+ E Sbjct: 1046 VQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105 Query: 1155 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIH-EAAVQE 1213 K + + E E S A+ E R +E +E K L+ + + V E Sbjct: 1106 PKPGHKRTDSTHS-SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164 Query: 1214 LRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR-AELSSLQTARQEGEQRRR 1272 L Q EL + EQ R K A E E ++R AEL RQE E + Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSK--------AKEEERPQIRGAELEYESLKRQELESENK 1216 Query: 1273 RLELQLQEVQGRAGD--GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330 +L+ +L E++ + A A + +L +VS L+ + + + L Sbjct: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLIL------- 1269 Query: 1331 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1390 +QL +E +Q + S + + + + ++ + + R L ++QL Sbjct: 1270 RSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLL---ESQL 1326 Query: 1391 SEWRRRQEEEAGALEAG-EEARRRAAREAEALTQ--RLAEKTETVDRLERGRRRLQQELD 1447 +R E EA AL + + R+ + L Q +L + L+ RL E Sbjct: 1327 QSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENL 1386 Query: 1448 DATMDLEQQRQLVSTLEKKQRKFDQLLAE 1476 D LE+Q + V L+K+ + F + + E Sbjct: 1387 DLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1415 Score = 66.6 bits (161), Expect = 2e-10 Identities = 129/620 (20%), Positives = 244/620 (39%), Gaps = 106/620 (17%) Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237 S ++L E ++ +L++ ++E+ + ++ V++L G Sbjct: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955 Query: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1296 +E +LR++L LQ + +E + R+ +E+ D E+ R+E Sbjct: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008 Query: 1297 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1354 E R + E E + L E + L +E + ++ + + E KL ++ Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065 Query: 1355 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1410 ++ LR Q L E + ER +E T + + ++ + + E Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125 Query: 1411 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1470 E E + R E +E L D ++ L+ Q+++ ++KQ Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173 Query: 1471 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1530 D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222 Query: 1531 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALK 1590 L + + KS E+ A L Q+T + +EL ++ L L L Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILR---SQLV 1274 Query: 1591 TQHERDLQGRDEAGEERRRQLAKQLRDAEVERDE-ERKQRTLAVAARKKLEGELEELKAQ 1649 +Q E +Q +D+ + L D + +D+ E Q + + +L L++Q Sbjct: 1275 SQKEA-IQPKDDKNTMTDSTIL--LEDVQKMKDKGEIAQAYIGLKETNRL------LESQ 1325 Query: 1650 MASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRE--SEKRLKG------ 1701 + S + E + LR +KE E R ++++ +QN + E R++ Sbjct: 1326 LQSQKRSHENEAEALRGEIQSLKE-----ENNR--QQQLLAQNLQLPPEARIEASLQHEI 1378 Query: 1702 --LEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GNLSKAAILEE------ 1747 L E L L E+L D+ R+ ++ A ++ N+S I++E Sbjct: 1379 TRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVN 1438 Query: 1748 -KRQLEGRLGQLEEELEEEQ 1766 R+ + G LE + E+EQ Sbjct: 1439 IPRKEKDFQGMLEYKKEDEQ 1458 Score = 65.1 bits (157), Expect = 7e-10 Identities = 103/551 (18%), Positives = 229/551 (41%), Gaps = 92/551 (16%) Query: 1423 QRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482 ++L + +V+R ++ ++ ++ +++Q + L +K + + E + Sbjct: 906 KKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLR 965 Query: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGK 1542 +E + +E E + R LSL +EE+ + LR +LE S K K Sbjct: 966 SDLERLQLSEEEAKVATGRVLSL----------QEEIAK----LRKDLEQTRSEK----K 1007 Query: 1543 SVHE-LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRD 1601 + E +R + EQ ++L+ + T L+ E A + R +Q Sbjct: 1008 CIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL-----------------NHRIVQQAK 1050 Query: 1602 EAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMA------SAGQ 1655 E E ++L ++ + E++ ++ER + + +LE ++LK +M G Sbjct: 1051 EMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGH 1110 Query: 1656 GKEEAVKQLRKMQ-------AQMKELWREVEETRTSREEI-FSQNRESEKRLKGLEAEVL 1707 + ++ + + A+M+++ EE + + S + +KR+ LE E Sbjct: 1111 KRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQ 1170 Query: 1708 RLQEELAASD----RARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELE 1763 +Q+EL + R++ + ++ E+ +L + + E ++L+ L +L + L Sbjct: 1171 VMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230 Query: 1764 EEQSNSELLNDR--YRKLLLQVESLTTELSAERS----FSAKAESGRQQLE--------- 1808 E+ + YR L+ Q+ S++ EL + ++ S ++ ++ Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT 1290 Query: 1809 ------RQIQELR--GRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860 +Q+++ G + + G + +++ + L+S+ E + E R I S K Sbjct: 1291 DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEA-LRGEIQSLKE 1349 Query: 1861 VRRAEKRLKEVVLQVEEERRVADQLR--------------DQLEKGNLRVKQLKRQLEEA 1906 +++L LQ+ E R+ L+ +QLEK + V++LK+QL+ Sbjct: 1350 ENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVF 1409 Query: 1907 EEEASRAQAGR 1917 ++ + G+ Sbjct: 1410 AKKIGELEVGQ 1420 Score = 41.6 bits (96), Expect = 0.008 Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%) Query: 1751 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1810 +E ++ QL+ +++E+ + + L VE LT + E ++++ E R LER Sbjct: 925 MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971 Query: 1811 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1870 +L EE+A + +L+ ++A+ + LEQ E+ + R ++ ++ Sbjct: 972 ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022 Query: 1871 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1930 +V ++EE + Q ++ L N R+ Q +++ E E+ + ++L+ +L D Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077 Query: 1931 AESMNREVTTLRNR 1944 +++ E + L R Sbjct: 1078 YQNLLNEFSRLEER 1091 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 542 bits (1397), Expect = e-153 Identities = 467/1489 (31%), Positives = 727/1489 (48%), Gaps = 127/1489 (8%) Query: 56 VWVPSELHGFEAAALRDEGEEEAEVELA--ESGRRLRLPRDQIQR-----MNPPKFSKAE 108 VW+P +++A L + + +V L E G+ L D + NP Sbjct: 13 VWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPDILVGEN 72 Query: 109 DMAELTCLNEASVLHNLRERYY-SGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167 D+ L+ L+E +VLHNLR R+ S LIYTY G+ V INPY+QLPIY E I+ Y G+ Sbjct: 73 DLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQNM 132 Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227 ++ PH++AV E AY+ M +D +QSI+ +GESGAGKT + K ++Y A V+ S Sbjct: 133 GDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS---- 188 Query: 228 PGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287 +E ++L +NPI+E+ GNAKT +NDNSSRFGK+I I FD I+GAN+ TYLLE Sbjct: 189 ---EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLE 245 Query: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNG--PSSSPGQERELF 345 KSR + QA++E ++HIFYQL A L L ++ + G P + + Sbjct: 246 KSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEM 305 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKL-CRLL 404 T ++ +LG S + + R+++ +L GN+ R+ D T+P + C L+ Sbjct: 306 AHTRQACTLLGISESHQMGIFRILAGILHLGNVGF-TSRDADSCTIPPKHEPLCIFCDLM 364 Query: 405 GLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALD 464 G+ + L ++ + K +K QA A +ALAK Y +LF W+V +N+AL Sbjct: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424 Query: 465 RSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIP 524 + +Q SF+G+LDI GFE F++NSFEQ CINY NEKLQQ FN +F LEQEEY +E IP Sbjct: 425 SAVKQ-HSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQIP 483 Query: 525 WTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQ-GGHPKFQ 583 WT +DF D QPCI+LIE + G+L LLDEEC PK TD ++ +K+ F+ Sbjct: 484 WTLIDF-YDNQPCINLIE---SKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFE 539 Query: 584 RPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG 643 +PR L ++A F + H+A KV+Y+ +L KN D + + +L S ++ E+++D E Sbjct: 540 KPR-LSNKA-FIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEK 597 Query: 644 IVGLEQVSSLG--------DGPPGGRP---RRGMFRTVGQLYKESLSRLMATLSNTNPSF 692 + +S G P GRP + +TVG ++ SL LM TL+ T P + Sbjct: 598 AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHY 657 Query: 693 VRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNA 752 VRCI PN K + + + QLR GVLE IRI GFP+R +QEF RY +L Sbjct: 658 VRCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQ- 716 Query: 753 IPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQA 812 D KQ C+ +++ L LD + Y+ G++KIFFRAG +A LE+ R K+ + Q Sbjct: 717 -KDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQK 775 Query: 813 AARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQ 872 RG+L R+ K + + A MQR Y + R + + TK ++Q + V++ Sbjct: 776 TIRGWLLRK---KYLRMRKAAITMQRYVRGY-QARCYAKFLRRTKAATIIQKYWRMYVVR 831 Query: 873 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAA 932 R ++++ + QS L+G +A R R + LR + + + RG LA Sbjct: 832 -RRYKIRRAATIVLQS-----YLRGFLA-----RNRYRKILREHKAVIIQ-KRVRGWLAR 879 Query: 933 R--KQELELVVSELEARVGEEEECSRQM--QTEKKRLQQHIQELEAHLEAEEGARQK-LQ 987 K+ + ++ + C R+M + E K+L+ + +E + + G K +Q Sbjct: 880 THYKRSMHAII--------YLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQ 931 Query: 988 LEKVTTEAK--MKKFEEDLLLLED-QNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNK 1044 L++ E K E L LE NS+ K R LE RL Q +EEE KV + Sbjct: 932 LQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLE-RL-----QLSEEEAKVATGRV 985 Query: 1045 LRLKYE-ATIADMEDRLRKEEKGRQE-LEKLKRRLDGESSELQEQMVEQQQRAEELRAQL 1102 L L+ E A + ++ R E+K +E ++ K+ + S L+E+ +Q E L ++ Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045 Query: 1103 GRKEEELQAALARAEDEGGARAQL--------LKSLREAQAALAEAQEDLESERVARTKA 1154 ++ +E+ + + E + +L ++L + L E +DL+ E Sbjct: 1046 VQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHV 1105 Query: 1155 EKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIH-EAAVQE 1213 K + + E E S A+ E R +E +E K L+ + + V E Sbjct: 1106 PKPGHKRTDSTHS-SNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTE 1164 Query: 1214 LRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELR-AELSSLQTARQEGEQRRR 1272 L Q EL + EQ R K A E E ++R AEL RQE E + Sbjct: 1165 LEQEKQVMQDELDRKEEQVLRSK--------AKEEERPQIRGAELEYESLKRQELESENK 1216 Query: 1273 RLELQLQEVQGRAGD--GERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330 +L+ +L E++ + A A + +L +VS L+ + + + L +L S Sbjct: 1217 KLKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQ 1276 Query: 1331 EAQ----------------LHDAQELLQEETRAKLALG----SRVRAMEAEAAGLREQLE 1370 + L D Q++ + A+ +G +R A++ +L Sbjct: 1277 KEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELW 1336 Query: 1371 EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAG-EEARRRAAREAEALTQ--RLAE 1427 ++A R L ++QL +R E EA AL + + R+ + L Q +L Sbjct: 1337 LVYEGLKQANRLL---ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPP 1393 Query: 1428 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1476 + L+ RL E D LE+Q + V L+K+ + F + + E Sbjct: 1394 EARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGE 1442 Score = 77.4 bits (189), Expect = 1e-13 Identities = 141/606 (23%), Positives = 240/606 (39%), Gaps = 133/606 (21%) Query: 1328 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE----EEAAARERAGREL 1383 S TE D + L E AK+A G RV +++ E A LR+ LE E+ E A R Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATG-RVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYK 1017 Query: 1384 QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQ 1443 Q + +S + EE L+ +EA + Q+ E TET+++ +L Sbjct: 1018 QETEQLVSNLK----EENTLLKQEKEALNHR------IVQQAKEMTETMEK------KLV 1061 Query: 1444 QELDDATMDLEQQR----QLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRERE 1499 +E +DL +R L++ + + ++D L E V +R ++ E Sbjct: 1062 EETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNE 1121 Query: 1500 ARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAAN 1559 + + + E E E + + ++ L Sbjct: 1122 SEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLK------------------------ 1157 Query: 1560 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1619 L+ +VTELE E +D R E V R +A EE R Q+R AE Sbjct: 1158 -LQKRVTELEQEKQVMQDELDRKEEQVL------------RSKAKEEER----PQIRGAE 1200 Query: 1620 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1679 +E + ++Q + KKL+ EL EL+ ++ K ++ A +R + Sbjct: 1201 LEYESLKRQEL--ESENKKLKNELNELRKALSE---------KSAPEVTAPGAPAYRVLM 1249 Query: 1680 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1739 E TS E +E EVL L+ +L + A Q + D++ M D Sbjct: 1250 EQLTSVSEELDVRKE----------EVLILRSQLVSQKEAI-QPKDDKNTMTDSTI---- 1294 Query: 1740 SKAAILEEKRQLE--GRLGQLEEELEEEQSNSEL----LNDRYRKLLLQVESLTTELSAE 1793 +LE+ ++++ G + Q L+E +S L LN+ +L L E L A Sbjct: 1295 ----LLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNED-GELWLVYEGLK---QAN 1346 Query: 1794 RSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRE 1853 R ++ +S ++ E + + LRG I +L+ E ++ Sbjct: 1347 RLLESQLQSQKRSHENEAEALRGE---------------IQSLKE---------ENNRQQ 1382 Query: 1854 RILSGKLVRRAEKRLKEVVLQVEEERRVADQL--RDQLEKGNLRVKQLKRQLEEAEEEAS 1911 ++L+ L E R+ E LQ E R + L +QLEK + V++LK+QL+ ++ Sbjct: 1383 QLLAQNLQLPPEARI-EASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIG 1441 Query: 1912 RAQAGR 1917 + G+ Sbjct: 1442 ELEVGQ 1447 Score = 63.5 bits (153), Expect = 2e-09 Identities = 128/635 (20%), Positives = 250/635 (39%), Gaps = 109/635 (17%) Query: 1178 STNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKG 1237 S ++L E ++ +L++ ++E+ + ++ V++L G Sbjct: 914 SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEG------------------ 955 Query: 1238 AWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA- 1296 +E +LR++L LQ + +E + R+ +E+ D E+ R+E Sbjct: 956 -------IYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKC 1008 Query: 1297 --EKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1354 E R + E E + L E + L +E + ++ + + E KL ++ Sbjct: 1009 IEEHADRYKQETEQLVSNLKEENTL---LKQEKEALNHRIVQQAKEMTETMEKKLVEETK 1065 Query: 1355 VRAMEAEAAGLREQ--LEEEAAARERAG--RELQTAQAQLSEWRRRQEEEAGALEAGEEA 1410 ++ LR Q L E + ER +E T + + ++ + + E Sbjct: 1066 QLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYI 1125 Query: 1411 RRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKF 1470 E E + R E +E L D ++ L+ Q+++ ++KQ Sbjct: 1126 FSSEIAEMEDIPSRTEEPSEKKVPL------------DMSLFLKLQKRVTELEQEKQVMQ 1173 Query: 1471 DQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAEL 1530 D+L +E+ + +E ER + G E LE E R+ELE +N+ L+ EL Sbjct: 1174 DELDRKEEQVLRSKAKEEERPQIRGAE-----------LEYESLKRQELESENKKLKNEL 1222 Query: 1531 EALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTV---- 1586 L + + KS E+ A L Q+T + +EL ++ L L + Sbjct: 1223 NELRKALSE--KSAPEVTAP---GAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277 Query: 1587 QALKTQHER-----------DLQGRDEAGEERRRQ--LAKQLRDAEVERDEERKQRTLAV 1633 +A++ + ++ D+Q + GE + L + R + ++ E + L + Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337 Query: 1634 A------ARKKLEGELEELK---AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1684 A + LE +L+ K A A +G+ +++K+ Q Q+ L + ++ + Sbjct: 1338 VYEGLKQANRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL--LAQNLQLPPEA 1395 Query: 1685 REEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVAN------GN 1738 R E Q+ + L E L L E+L D+ R+ ++ A ++ N Sbjct: 1396 RIEASLQH-----EITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELEVGQMEN 1450 Query: 1739 LSKAAILEE-------KRQLEGRLGQLEEELEEEQ 1766 +S I++E R+ + G LE + E+EQ Sbjct: 1451 ISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQ 1485 Score = 41.6 bits (96), Expect = 0.008 Identities = 42/194 (21%), Positives = 92/194 (47%), Gaps = 27/194 (13%) Query: 1751 LEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQ 1810 +E ++ QL+ +++E+ + + L VE LT + E ++++ E R LER Sbjct: 925 MENKIMQLQRKVDEQNKDYKCL----------VEKLT---NLEGIYNSETEKLRSDLERL 971 Query: 1811 IQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1870 +L EE+A + +L+ ++A+ + LEQ E+ + R ++ ++ Sbjct: 972 ------QLSEEEAKVATGR---VLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQ 1022 Query: 1871 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1930 +V ++EE + Q ++ L N R+ Q +++ E E+ + ++L+ +L D Sbjct: 1023 LVSNLKEENTLLKQEKEAL---NHRIVQQAKEMTETMEK--KLVEETKQLELDLNDERLR 1077 Query: 1931 AESMNREVTTLRNR 1944 +++ E + L R Sbjct: 1078 YQNLLNEFSRLEER 1091 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 536 bits (1381), Expect = e-152 Identities = 443/1659 (26%), Positives = 783/1659 (47%), Gaps = 162/1659 (9%) Query: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104 W VW+ GF A+ L+ E E + V+L G L + D +++ N P Sbjct: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404 Query: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164 + ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G Sbjct: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464 Query: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224 +R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G Sbjct: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523 Query: 225 RKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 284 K V + Q L +LEAFGN+ T+ N N++RF + + ++FD AG + A+I+T Sbjct: 524 NKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTM 578 Query: 285 LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQEREL 344 LLEK R R+ E +F++FY LL L+ +L L + P + P ++++ Sbjct: 579 LLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKA 638 Query: 345 ---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMPDNTAAQKL 400 F + +++VLG S +E + +++A+ G A K + + AQK Sbjct: 639 AQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698 Query: 401 CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------ADFALEALA 444 LLG + + S A+ + K G +Q++ + Q A LE +A Sbjct: 699 AYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMA 756 Query: 445 KATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SFEQLCINYT 498 Y LF LV +NRAL S S + I+D GF+ + SFE+LC NYT Sbjct: 757 AGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNYT 815 Query: 499 NEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP---------- 548 ++LQ+LF+ FV E E Y+ E I F D + +++ ++ Sbjct: 816 QDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDE 875 Query: 549 --GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADFSVLHYAGK 602 GLL LL+EE P A++ + +E++ G G K Q P H F + H G Sbjct: 876 ARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGT 935 Query: 603 --VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG--------IVGLEQVS 651 V+Y WL +P N LL S ++ + ++ G I GLE S Sbjct: 936 NWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGS 995 Query: 652 SLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVRCIVPNHEK 702 L R F T + + K+SL L+ T+ + FV C +P E Sbjct: 996 QLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEG 1053 Query: 703 RAGK-----------------------------LEPRLVLDQLRCNGVLEGIRICRQGFP 733 AG+ L+ L+ QLR + +L+ +R+ RQG+P Sbjct: 1054 WAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYP 1113 Query: 734 NRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRVGQSKIFFR 788 + ++F EFR+R+++L P+ K +D ++A E++++ L+L+ + +G S++FFR Sbjct: 1114 DHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFR 1173 Query: 789 AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH 848 AG LA+LEE+RD + + + FQAA RGYLAR+ F+KR+ Q A+R +Q+N ++ Sbjct: 1174 AGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233 Query: 849 WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 908 W WW+LFT V+PL++V +E ++ + +E+Q+++ +++ +E EL+ +LE + Sbjct: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISE 1293 Query: 909 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 968 L +L E A + A + E + EL+ + + +QM+ + + + Sbjct: 1294 LTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT---QYDALKKQMEVMEMEVMEA 1350 Query: 969 --IQELEAHLEAEE---GARQKLQLEKVT-----TEAKMKKFEEDLLLLEDQNSKLSKER 1018 I+ E + E ++ G +L+ E+ T+ ++++ ED L +E QN + Sbjct: 1351 RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN------K 1404 Query: 1019 KLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLD 1078 + LE RL + + + E + ++ L K + A + D + L ++ ELEK +RR D Sbjct: 1405 RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFD 1464 Query: 1079 GESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALA 1138 E S+ E+ ++ + E+L+ + E + + E++ A + + +A L Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524 Query: 1139 EAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKK 1198 + + + K +KQ RDL +++ EL++ + ++ + + E E+ +++ Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584 Query: 1199 TLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELS 1258 T +E + V+E RQ + L ++ QLE+ K + + LE +++ L Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATL----- 1639 Query: 1259 SLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAES 1318 S Q R++ E +RL L+ + D + + + ++ E+ + L E+E Sbjct: 1640 SDQVNRRDFES-EKRLRKDLKRTKALLADAQ-LMLDHLKNSAPSKREIAQLKNQLEESEF 1697 Query: 1319 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE------ 1372 K + E ++ D + + +AK AL ++ ++ E ++ +LEE+ Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNE 1757 Query: 1373 -----AAARERAGREL---QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQR 1424 AA +A R+L QAQL E + ++E L+A + + E L Q Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS-------QVEFLEQS 1810 Query: 1425 LAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRA 1484 + +K+ V R E R L+ L+ +++ L S L++ K + + AA R Sbjct: 1811 MVDKS-LVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE 1869 Query: 1485 VEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSV 1544 E+ +R + + R+ + L R E + ELE +L A ++L + K + Sbjct: 1870 KEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRI 1929 Query: 1545 HELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLE 1583 +L+ A E +++ + L+D +T + K +LE Sbjct: 1930 GDLQAAIE-DEMESDENEDLINSLQDMVTKYQKRKNKLE 1967 Score = 192 bits (489), Expect = 2e-48 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%) Query: 1271 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330 R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+ Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301 Query: 1331 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1370 A +LL ET +L ++ ++ + L++Q+E Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361 Query: 1371 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1427 ++A R E + ++ R +QE E LE ++ +R+ R L E Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420 Query: 1428 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1487 + +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R + Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480 Query: 1488 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1547 RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++ Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540 Query: 1548 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1607 ++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600 Query: 1608 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667 R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657 Query: 1668 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1727 + K L + + + + S++ + L+ ++ + AA+ +AR+ + + Sbjct: 1658 LKRTKALLADAQ----LMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713 Query: 1728 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1787 +++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773 Query: 1788 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1847 +++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831 Query: 1848 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1905 E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL + Sbjct: 1832 EFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882 Query: 1906 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1938 +E E +R +A R + ELE ES E+ N+ + Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918 Score = 157 bits (396), Expect = 1e-37 Identities = 164/804 (20%), Positives = 350/804 (43%), Gaps = 121/804 (15%) Query: 1085 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144 +EQ+ + + ++LR++L + E+E ++ ++L L + + A + L Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312 Query: 1145 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1186 ++E R +AEK+ ++L + +AL+ ++E +D +A E R Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372 Query: 1187 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 L AE+ + + L Q E E+++RR + +L + A EKLQR Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 +L +E A+ ++ L+E+ +V ++EAE Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423 + Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584 Query: 1424 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482 +++ E+ D +E R+ Q++L + LE++ E+K VL Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626 Query: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1535 R E+ E EG+ R E E+ R++L+R +AL A+ + +L Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680 Query: 1536 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1585 SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+ Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740 Query: 1586 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1639 ++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800 Query: 1640 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1683 + ++E L+ M ++EA VK+L + +++KE ++ E R Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860 Query: 1684 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1743 R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + + Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917 Query: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESG 1803 + + + R+G L+ +E+E +D L+ ++ + T+ ++ Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEME-----SDENEDLINSLQDMVTKYQKRKNKLEGDSDV 1972 Query: 1804 RQQLERQIQELRGRLGEEDAGARA 1827 +LE ++ ++ L + ++A Sbjct: 1973 DSELEDRVDGVKSWLSKNKGPSKA 1996 Score = 116 bits (291), Expect = 2e-25 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%) Query: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519 V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308 Query: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1575 + A AE ++ L++ V E + R A++ D+ A Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368 Query: 1576 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632 + +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426 Query: 1633 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1690 +K +L EL++ K + E K+ R+ +++ + E + + RE++ Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484 Query: 1691 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1743 RE + L AE L+++L D + + + +++ + + S A Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539 Query: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1802 + ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599 Query: 1803 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860 RQ +++++++ +L EE D R K LE KLA +Q+ + E S K Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653 Query: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920 +R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ + Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709 Query: 1921 QRELEDVTESAESMNREVTTLRNRLRR 1947 + E+ED+ + + + T L +L R Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736 Score = 109 bits (272), Expect = 3e-23 Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%) Query: 1387 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1440 + QLSE + R ++E LE E+ R ++ L R++E T E D G Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307 Query: 1441 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1496 Q +D E +L + E K Q ++D L + + + +E R AE G Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361 Query: 1497 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1540 ER R + T+ L++E E + E+E+QN R L L L + ++ Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421 Query: 1541 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1600 +++ +L++ C+ D + + + E + R + + + +R+ R Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481 Query: 1601 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1658 ++ E+ LA+ +++ E K +A +K LE EL+++ +Q + Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538 Query: 1659 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1715 + KQLR ++A++K+ E++E + + + E +R++ ++ + ++E Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597 Query: 1716 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1775 + AR+ Q+ +M ++ K +L EKR+LEG+L L +++ SE R Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653 Query: 1776 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1835 RK L + ++L + + + R+I +L+ +L E + T AA Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701 Query: 1836 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1895 +A + +E E + L + +A+ L+E + +++ E+ ++++++LE+ Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754 Query: 1896 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1945 + +L ++ + A +ASR A LQ +LE+ + + + ++ L++++ Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804 Score = 59.3 bits (142), Expect = 4e-08 Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%) Query: 1676 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1735 R + E + S E+I +++ E ++ LE E SDR + + E+ DE Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303 Query: 1736 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1795 G S + +L+ + E L E+ E L +Y L Q+E + E+ R Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352 Query: 1796 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1855 A E+ G + ++DAG R K A E +++L+QE +++ Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397 Query: 1856 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1900 + + R+ E+RL ++ EE +R QL+ + LE +R +L+ Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457 Query: 1901 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1953 + +L +A EEA R + R +LQRE + + A S+ +++ + FT Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513 Query: 1954 TRTVRQVFRLEEGVASDEEAEEA 1976 + V L++ ++S E +EA Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 531 bits (1368), Expect = e-150 Identities = 443/1667 (26%), Positives = 783/1667 (46%), Gaps = 167/1667 (10%) Query: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104 W VW+ GF A+ L+ E E + V+L G L + D +++ N P Sbjct: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404 Query: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164 + ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G Sbjct: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464 Query: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224 +R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G Sbjct: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523 Query: 225 RKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 284 K V + Q L +LEAFGN+ T+ N N++RF + + ++FD AG + A+I+T Sbjct: 524 NKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTM 578 Query: 285 LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQEREL 344 LLEK R R+ E +F++FY LL L+ +L L + P + P ++++ Sbjct: 579 LLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKA 638 Query: 345 ---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMPDNTAAQKL 400 F + +++VLG S +E + +++A+ G A K + + AQK Sbjct: 639 AQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698 Query: 401 CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------ADFALEALA 444 LLG + + S A+ + K G +Q++ + Q A LE +A Sbjct: 699 AYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMA 756 Query: 445 KATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SFEQLCINYT 498 Y LF LV +NRAL S S + I+D GF+ + SFE+LC NYT Sbjct: 757 AGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNYT 815 Query: 499 NEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP---------- 548 ++LQ+LF+ FV E E Y+ E I F D + +++ ++ Sbjct: 816 QDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDE 875 Query: 549 --GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADFSVLHYAGK 602 GLL LL+EE P A++ + +E++ G G K Q P H F + H G Sbjct: 876 ARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGT 935 Query: 603 --VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG--------IVGLEQVS 651 V+Y WL +P N LL S ++ + ++ G I GLE S Sbjct: 936 NWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGS 995 Query: 652 SLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVRCIVPNHEK 702 L R F T + + K+SL L+ T+ + FV C +P E Sbjct: 996 QLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEG 1053 Query: 703 RAGK-----------------------------LEPRLVLDQLRCNGVLEGIRICRQGFP 733 AG+ L+ L+ QLR + +L+ +R+ RQG+P Sbjct: 1054 WAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYP 1113 Query: 734 NRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRVGQSKIFFR 788 + ++F EFR+R+++L P+ K +D ++A E++++ L+L+ + +G S++FFR Sbjct: 1114 DHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFR 1173 Query: 789 AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH 848 AG LA+LEE+RD + + + FQAA RGYLAR+ F+KR+ Q A+R +Q+N ++ Sbjct: 1174 AGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233 Query: 849 WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 908 W WW+LFT V+PL++V +E ++ + +E+Q+++ +++ +E EL+ +LE + Sbjct: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISE 1293 Query: 909 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 968 L +L E A + A + E + EL+ + + +QM+ + + + Sbjct: 1294 LTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT---QYDALKKQMEVMEMEVMEA 1350 Query: 969 --IQELEAHLEAEE---GARQKLQLEKVT-----TEAKMKKFEEDLLLLEDQNSKLSKER 1018 I+ E + E ++ G +L+ E+ T+ ++++ ED L +E QN + Sbjct: 1351 RLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN------K 1404 Query: 1019 KLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLD 1078 + LE RL + + + E + ++ L K + A + D + L ++ ELEK +RR D Sbjct: 1405 RQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFD 1464 Query: 1079 GESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALA 1138 E S+ E+ ++ + E+L+ + E + + E++ A + + +A L Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524 Query: 1139 EAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKK 1198 + + + K +KQ RDL +++ EL++ + ++ + + E E+ +++ Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584 Query: 1199 TLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELS 1258 T +E + V+E RQ + L ++ QLE+ K + + LE +++ L Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATL----- 1639 Query: 1259 SLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAES 1318 S Q R++ E +RL L+ + D + + + ++ E+ + L E+E Sbjct: 1640 SDQVNRRDFES-EKRLRKDLKRTKALLADAQ-LMLDHLKNSAPSKREIAQLKNQLEESEF 1697 Query: 1319 KTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEE------ 1372 K + E ++ D + + +AK AL ++ ++ E ++ +LEE+ Sbjct: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNE 1757 Query: 1373 -----AAARERAGREL---QTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQR 1424 AA +A R+L QAQL E + ++E L+A + + E L Q Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS-------QVEFLEQS 1810 Query: 1425 LAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRA 1484 + +K+ V R E R L+ L+ +++ L S L++ K + + AA R Sbjct: 1811 MVDKS-LVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE 1869 Query: 1485 VEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSV 1544 E+ +R + + R+ + L R E + ELE +L A ++L + K + Sbjct: 1870 KEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRI 1929 Query: 1545 HELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKT 1591 +L+ A + ++ +D + E + D LE V +K+ Sbjct: 1930 GDLQAA--IEDEMESDENEDLINSEGD----SDVDSELEDRVDGVKS 1970 Score = 192 bits (489), Expect = 2e-48 Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%) Query: 1271 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330 R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+ Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301 Query: 1331 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1370 A +LL ET +L ++ ++ + L++Q+E Sbjct: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361 Query: 1371 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1427 ++A R E + ++ R +QE E LE ++ +R+ R L E Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420 Query: 1428 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1487 + +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R + Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480 Query: 1488 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1547 RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++ Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540 Query: 1548 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1607 ++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600 Query: 1608 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667 R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657 Query: 1668 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1727 + K L + + + + S++ + L+ ++ + AA+ +AR+ + + Sbjct: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713 Query: 1728 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1787 +++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q Sbjct: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773 Query: 1788 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1847 +++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L Sbjct: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831 Query: 1848 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1905 E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL + Sbjct: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882 Query: 1906 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1938 +E E +R +A R + ELE ES E+ N+ + Sbjct: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918 Score = 156 bits (394), Expect = 2e-37 Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%) Query: 1085 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144 +EQ+ + + ++LR++L + E+E ++ ++L L + + A + L Sbjct: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312 Query: 1145 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1186 ++E R +AEK+ ++L + +AL+ ++E +D +A E R Sbjct: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372 Query: 1187 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243 K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K Sbjct: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432 Query: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303 L AE+ + + L Q E E+++RR + +L + A EKLQR Sbjct: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482 Query: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363 +L +E A+ ++ L+E+ +V ++EAE Sbjct: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524 Query: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423 + Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q Sbjct: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584 Query: 1424 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482 +++ E+ D +E R+ Q++L + LE++ E+K VL Sbjct: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626 Query: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1535 R E+ E EG+ R E E+ R++L+R +AL A+ + +L Sbjct: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680 Query: 1536 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1585 SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+ Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740 Query: 1586 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1639 ++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800 Query: 1640 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1683 + ++E L+ M ++EA VK+L + +++KE ++ E R Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860 Query: 1684 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1743 R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + + Sbjct: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917 Query: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSE 1770 + + + R+G L+ +E+E + E Sbjct: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944 Score = 116 bits (291), Expect = 2e-25 Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%) Query: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519 V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E Sbjct: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308 Query: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1575 + A AE ++ L++ V E + R A++ D+ A Sbjct: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368 Query: 1576 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632 + +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L Sbjct: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426 Query: 1633 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1690 +K +L EL++ K + E K+ R+ +++ + E + + RE++ Sbjct: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484 Query: 1691 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1743 RE + L AE L+++L D + + + +++ + + S A Sbjct: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539 Query: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1802 + ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E Sbjct: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599 Query: 1803 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860 RQ +++++++ +L EE D R K LE KLA +Q+ + E S K Sbjct: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653 Query: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920 +R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ + Sbjct: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709 Query: 1921 QRELEDVTESAESMNREVTTLRNRLRR 1947 + E+ED+ + + + T L +L R Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736 Score = 109 bits (272), Expect = 3e-23 Identities = 126/590 (21%), Positives = 263/590 (44%), Gaps = 64/590 (10%) Query: 1387 QAQLSEWRRRQEEEA-----GALEAGEEARRRAAREAEALTQRLAEKT-ETVDRLERGRR 1440 + QLSE + R ++E LE E+ R ++ L R++E T E D G Sbjct: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307 Query: 1441 RLQQELDDATMDLEQQRQLVSTLEKK--QRKFDQLLAEEKAAVLRAVEER--ERAEAEGR 1496 Q +D E +L + E K Q ++D L + + + +E R AE G Sbjct: 1308 ASQ------LLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361 Query: 1497 --------------EREARALSLTRA-LEEEQEAREELERQN-RALRAELEALLSSKDDV 1540 ER R + T+ L++E E + E+E+QN R L L L + ++ Sbjct: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421 Query: 1541 GKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGR 1600 +++ +L++ C+ D + + + E + R + + + +R+ R Sbjct: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481 Query: 1601 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARK--KLEGELEELKAQMASAGQGKE 1658 ++ E+ LA+ +++ E K +A +K LE EL+++ +Q + Sbjct: 1482 EKLQREKDMLLAEAF---SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538 Query: 1659 EAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESE---KRLKGLEAEVLRLQEELAA 1715 + KQLR ++A++K+ E++E + + + E +R++ ++ + ++E Sbjct: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV- 1597 Query: 1716 SDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDR 1775 + AR+ Q+ +M ++ K +L EKR+LEG+L L +++ SE R Sbjct: 1598 -EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE---KR 1653 Query: 1776 YRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAA 1835 RK L + ++L + + + R+I +L+ +L E + T AA Sbjct: 1654 LRKDLKRTKALLADAQLMLDHLKNSAPSK----REIAQLKNQLEESE--------FTCAA 1701 Query: 1836 LESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLR 1895 +A + +E E + L + +A+ L+E + +++ E+ ++++++LE+ Sbjct: 1702 A----VKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK---NEIQNRLEEDQED 1754 Query: 1896 VKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL 1945 + +L ++ + A +ASR A LQ +LE+ + + + ++ L++++ Sbjct: 1755 MNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQV 1804 Score = 59.3 bits (142), Expect = 4e-08 Identities = 76/323 (23%), Positives = 137/323 (42%), Gaps = 53/323 (16%) Query: 1676 REVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVA 1735 R + E + S E+I +++ E ++ LE E SDR + + E+ DE Sbjct: 1244 RPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303 Query: 1736 NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERS 1795 G S + +L+ + E L E+ E L +Y L Q+E + E+ R Sbjct: 1304 TGE-SASQLLD---------AETAERLRAEKEMKE-LQTQYDALKKQMEVMEMEVMEARL 1352 Query: 1796 FSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERI 1855 A E+ G + ++DAG R K A E +++L+QE +++ Sbjct: 1353 IRA-------------AEINGEVDDDDAGGEWRLKYERAVREVDF--TKKRLQQEFEDKL 1397 Query: 1856 -LSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQ--------------LEKGNLRVKQLK 1900 + + R+ E+RL ++ EE +R QL+ + LE +R +L+ Sbjct: 1398 EVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457 Query: 1901 R-------QLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFT 1953 + +L +A EEA R + R +LQRE + + A S+ +++ + FT Sbjct: 1458 KKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI----AGFT 1513 Query: 1954 TRTVRQVFRLEEGVASDEEAEEA 1976 + V L++ ++S E +EA Sbjct: 1514 QKVVSLEAELQD-ISSQESKDEA 1535 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 478 bits (1230), Expect = e-134 Identities = 317/936 (33%), Positives = 510/936 (54%), Gaps = 53/936 (5%) Query: 91 LPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQ 150 + ++ M+P +DMA LT L+ S+++NL +RY IYTY G +NPY+ Sbjct: 49 ITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQP 108 Query: 151 LP-IYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTK 209 + +Y A +E Y + E+PPH++A+ YR + + ++Q IL +GESGAGKTE+TK Sbjct: 109 IAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTK 168 Query: 210 KVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRIN 269 ++++L+ ++ +ER +L+++PI+EAFGNAKTV N+NSSRFGKF+++N Sbjct: 169 LILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLN 228 Query: 270 FDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRF 329 G I G I YLLEK+R +RQ E ++HIFY LL G + + + L +Y + Sbjct: 229 ICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHY 288 Query: 330 LTNG--PSSSPGQERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTD 387 L ++E F+E + ++ V+ FS EE+ + R+++ +L GNI Sbjct: 289 LNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAG 345 Query: 388 QATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKAT 447 A + TA + LLGL T + AL + + + + +QA + ++LA A Sbjct: 346 GAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMAL 405 Query: 448 YERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFN 507 Y F W++ ++N + + +GILDI GFE F++N FEQ INY NEKLQ+ FN Sbjct: 406 YACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFN 463 Query: 508 HTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKS 567 +F LEQ EY REG+ W +D+ +D C+DLIE+ GLLAL++EE FP+ATD + Sbjct: 464 KHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESHFPQATDST 519 Query: 568 FVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLH 627 +EK+ + + + +PR + +F V HYAG+V Y L KN D D++ LL Sbjct: 520 LLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLR 577 Query: 628 QSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSN 687 +S +++ E + +L G RP TV +K+SL LMATLS+ Sbjct: 578 ESRFDFIYDLF---EHVSSRNNQDTLKCGSKHRRP------TVSSQFKDSLHSLMATLSS 628 Query: 688 TNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEI 747 +NP FVRCI PN +K + + +VL+QLR +G+LE +RI + G+ R FQ+F +RY++ Sbjct: 629 SNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKV 688 Query: 748 LTPN-AIPKGFMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDI 806 L N A+P+ D + C ++Q + + +++G++K+F R + +LE+ R+ +V+ Sbjct: 689 LMRNLALPE---DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHA 745 Query: 807 IVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTR 866 + +A G+LAR+ ++K + ++Q+N A+L R R K + + Sbjct: 746 AMVIRAHVLGFLARKQYRK---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQK 797 Query: 867 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 926 Q AR Q + E ++Q ++ E + + + EEER R E+ R EAEL A+ EE Sbjct: 798 QLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER--ERERREAELRAQQEE- 854 Query: 927 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQE-LEAHLEAEEGARQK 985 RKQ+ ELEA ++E + EK++ + ++E L E E+ R K Sbjct: 855 ----ETRKQQ------ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMK 904 Query: 986 LQLEKVTTEAKMKKFEE----DLLLLEDQNSKLSKE 1017 Q E TEA ++K +E +L LE++ + ++E Sbjct: 905 EQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940 Score = 53.5 bits (127), Expect = 2e-06 Identities = 70/233 (30%), Positives = 113/233 (48%), Gaps = 31/233 (13%) Query: 1340 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQ-E 1398 ++Q+ RA L L R ++ A ++QL + A R R+L A+ + E +++Q E Sbjct: 771 IIQKNYRAFL-LRRRFLHLKKAAIVFQKQLRGQIA--RRVYRQL-LAEKREQEEKKKQEE 826 Query: 1399 EEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQ 1458 EE E E R R REAE Q+ E R QQEL +A +++ + Sbjct: 827 EEKKKREEEERERERERREAELRAQQEEE------------TRKQQEL-EALQKSQKEAE 873 Query: 1459 LVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRA-LEEEQEAR- 1516 L LEK++ ++ +LR +E E + R +E + LSLT A L++ QE R Sbjct: 874 LTRELEKQKEN------KQVEEILRLEKEIEDLQ---RMKEQQELSLTEASLQKLQERRD 924 Query: 1517 EELER-QNRALRAELEALLS-SKDDVGKSVHELERACRVAEQAANDLRAQVTE 1567 +EL R + A RA E L S + D++ + V +ER+ V + +++L E Sbjct: 925 QELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACE 977 Score = 47.0 bits (110), Expect = 2e-04 Identities = 45/148 (30%), Positives = 72/148 (48%), Gaps = 12/148 (8%) Query: 984 QKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLN 1043 ++L EK E K K+ EE+ E++ + +ER R AE +Q EE K + L Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERER-----REAELRAQQEEETRKQQELE 863 Query: 1044 KLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG 1103 L+ + A++ L K+++ +Q E L RL+ E +LQ +++QQ A L Sbjct: 864 ALQKSQKE--AELTRELEKQKENKQVEEIL--RLEKEIEDLQR--MKEQQELSLTEASLQ 917 Query: 1104 RKEEELQAALARAEDEGGARAQ-LLKSL 1130 + +E L R E+E AQ L+SL Sbjct: 918 KLQERRDQELRRLEEEACRAAQEFLESL 945 Score = 45.8 bits (107), Expect = 4e-04 Identities = 36/141 (25%), Positives = 74/141 (52%), Gaps = 12/141 (8%) Query: 1096 EELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAE 1155 ++LR Q+ R+ A R ++E + + K RE + E +E E+E A+ + E Sbjct: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE-RERREAELRAQQEEE 855 Query: 1156 KQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLE--------EETRIH 1207 +++ +ELEAL+ ++ + +++ +K+ +E+ L+K +E +E + Sbjct: 856 TRKQ---QELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLT 912 Query: 1208 EAAVQELRQRHGQALGELAEQ 1228 EA++Q+L++R Q L L E+ Sbjct: 913 EASLQKLQERRDQELRRLEEE 933 Score = 43.9 bits (102), Expect = 0.002 Identities = 38/156 (24%), Positives = 73/156 (46%), Gaps = 20/156 (12%) Query: 1764 EEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDA 1823 ++Q ++ YR+LL + + E K E ++ ER+ +E R +E+ Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEE- 854 Query: 1824 GARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEE----R 1879 E++ Q E L++ +E L+ +L ++ E + E +L++E+E + Sbjct: 855 -------------ETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ 901 Query: 1880 RVADQLRDQLEKGNLRVKQLKR--QLEEAEEEASRA 1913 R+ +Q L + +L+ Q +R +L EEEA RA Sbjct: 902 RMKEQQELSLTEASLQKLQERRDQELRRLEEEACRA 937 Score = 43.9 bits (102), Expect = 0.002 Identities = 41/177 (23%), Positives = 79/177 (44%), Gaps = 14/177 (7%) Query: 1046 RLKYEATIADMEDRLRK-----EEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1100 R Y +A+ ++ K EEK ++E E+ +R + +EL+ Q E+ ++ +EL A Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA 864 Query: 1101 -QLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRR 1159 Q +KE EL L + ++ + ++ + + + + Q E + ++ T+A Q+ Sbjct: 865 LQKSQKEAELTRELEKQKEN-----KQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL 919 Query: 1160 DLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQ 1216 + E R E E AQ+ L S E+ E + +E + EL + Sbjct: 920 QERRDQELRRLEEE---ACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973 Score = 43.9 bits (102), Expect = 0.002 Identities = 54/182 (29%), Positives = 90/182 (49%), Gaps = 38/182 (20%) Query: 1056 MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLG---RKEEELQAA 1112 + ++ +EEK +QE E+ K+R E +E+ E+++R ELRAQ RK++EL+A Sbjct: 812 LAEKREQEEKKKQEEEEKKKR------EEEERERERERREAELRAQQEEETRKQQELEA- 864 Query: 1113 LARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEAL-RGE 1171 L KS +EA E +LE ++ + E R L +E+E L R + Sbjct: 865 -------------LQKSQKEA-----ELTRELEKQKENKQVEEILR--LEKEIEDLQRMK 904 Query: 1172 LEDTLDSTNAQ-QELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLE 1230 + L T A Q+L+ +R+QE+ + LEEE AA + L + + E +E Sbjct: 905 EQQELSLTEASLQKLQERRDQEL----RRLEEEA--CRAAQEFLESLNFDEIDECVRNIE 958 Query: 1231 QA 1232 ++ Sbjct: 959 RS 960 Score = 42.0 bits (97), Expect = 0.006 Identities = 38/148 (25%), Positives = 72/148 (48%), Gaps = 10/148 (6%) Query: 1552 RVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQ- 1610 ++A + L A+ E E++ E+ K + E + + + R+ + R + EE R+Q Sbjct: 802 QIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQ 860 Query: 1611 ----LAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRK 1666 L K ++AE+ R+ E+++ V +LE E+E+L+ EA L+K Sbjct: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA--SLQK 918 Query: 1667 MQAQMKELWREVEE--TRTSREEIFSQN 1692 +Q + + R +EE R ++E + S N Sbjct: 919 LQERRDQELRRLEEEACRAAQEFLESLN 946 Score = 41.2 bits (95), Expect = 0.010 Identities = 41/139 (29%), Positives = 69/139 (49%), Gaps = 19/139 (13%) Query: 1137 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTEL 1196 LAE +E + E+ + + EK++R+ EE E R E L AQQE ++++QE+ L Sbjct: 812 LAEKRE--QEEKKKQEEEEKKKRE-EEERERERERREAEL---RAQQEEETRKQQELEAL 865 Query: 1197 KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAE 1256 +K+ +E E Q+ ++ + L L +++E +R K E EL Sbjct: 866 QKSQKEAELTRELEKQKENKQVEEIL-RLEKEIEDLQRMK------------EQQELSLT 912 Query: 1257 LSSLQTARQEGEQRRRRLE 1275 +SLQ ++ +Q RRLE Sbjct: 913 EASLQKLQERRDQELRRLE 931 Score = 40.4 bits (93), Expect = 0.017 Identities = 64/262 (24%), Positives = 113/262 (43%), Gaps = 26/262 (9%) Query: 1560 DLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAE 1619 D+R + T L +L A +++ +L T L+ E+ L+ R E + + Sbjct: 698 DVRGKCTSLL-QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756 Query: 1620 VERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVE 1679 + R + RK V +K L L+ + + KQLR A Sbjct: 757 LARKQYRKVLYCVVIIQKNYRAFL--LRRRFLHLKKAAIVFQKQLRGQIA---------- 804 Query: 1680 ETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNL 1739 R ++ ++ RE E++ K E E + +EE +R RR+A+ R + +E Sbjct: 805 --RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAEL-RAQQEEETRKQQE 861 Query: 1740 SKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAK 1799 +A +K Q E +L ELE+++ N ++ + +L ++E L + ++ S Sbjct: 862 LEAL---QKSQKE---AELTRELEKQKENKQV--EEILRLEKEIEDL-QRMKEQQELSLT 912 Query: 1800 AESGRQQLERQIQELRGRLGEE 1821 S ++ ER+ QELR RL EE Sbjct: 913 EASLQKLQERRDQELR-RLEEE 933 Score = 38.9 bits (89), Expect = 0.051 Identities = 42/138 (30%), Positives = 66/138 (47%), Gaps = 11/138 (7%) Query: 1018 RKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKY-EATIADMEDRLRKEEKGRQELEKL-KR 1075 R+LL ++ + + EEEEK K + R + E A++ + +E + +QELE L K Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKS 868 Query: 1076 RLDGESSELQEQMVEQQQRAEELR-------AQLGRKEEELQAALARAEDEGGARAQLLK 1128 + + E + E+ E +Q E LR Q ++++EL A + R Q L+ Sbjct: 869 QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELR 928 Query: 1129 SLREAQAALAEAQEDLES 1146 L E A AQE LES Sbjct: 929 RLEE--EACRAAQEFLES 944 Score = 38.1 bits (87), Expect = 0.087 Identities = 33/128 (25%), Positives = 66/128 (51%), Gaps = 12/128 (9%) Query: 1812 QELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEV 1871 ++LRG++ AR ++ +A E + + +++ E+E +++ + R E+R E+ Sbjct: 797 KQLRGQI------ARRVYRQLLA--EKREQEEKKKQEEEEKKKREEEERERERERREAEL 848 Query: 1872 VLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESA 1931 Q EEE R +L + L+K + +L R+LE+ +E + RL++E+ED+ Sbjct: 849 RAQQEEETRKQQEL-EALQKSQ-KEAELTRELEKQKENKQVEEI--LRLEKEIEDLQRMK 904 Query: 1932 ESMNREVT 1939 E +T Sbjct: 905 EQQELSLT 912 Score = 37.7 bits (86), Expect = 0.11 Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 10/146 (6%) Query: 1206 IHEAAVQELRQRHGQALGE-----LAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSL 1260 + +AA+ +Q GQ LAE+ EQ + K E+ + E E R + Sbjct: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847 Query: 1261 QTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKT 1320 A+QE E R+++ +L+ +Q + E R +K + E+ + + + + Sbjct: 848 LRAQQEEETRKQQ---ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--R 902 Query: 1321 IRLSKELSSTEAQLHDAQELLQEETR 1346 ++ +ELS TEA L QE +E R Sbjct: 903 MKEQQELSLTEASLQKLQERRDQELR 928 Score = 37.0 bits (84), Expect = 0.19 Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 30/157 (19%) Query: 1331 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL 1390 E + + ++ +EE + K R R E A LR Q EEE Sbjct: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET----------------- 856 Query: 1391 SEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDAT 1450 R+Q+E LEA +++++ A E Q+ ++ E + RLE+ LQ+ + Sbjct: 857 ----RKQQE----LEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE 908 Query: 1451 MDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1487 + L + ++L+K Q + DQ L + RA +E Sbjct: 909 LSLTE-----ASLQKLQERRDQELRRLEEEACRAAQE 940 Score = 33.5 bits (75), Expect = 2.1 Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 4/122 (3%) Query: 1860 LVRRAEKRLKE--VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGR 1917 L+RR LK+ +V Q + ++A ++ QL ++ K+Q EE +++ + R Sbjct: 780 LLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER 839 Query: 1918 RRLQRELEDVTESAESMNR--EVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEE 1975 R +RE E + E + E+ L+ + LT ++ ++EE + ++E E+ Sbjct: 840 ERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIED 899 Query: 1976 AQ 1977 Q Sbjct: 900 LQ 901 Score = 32.7 bits (73), Expect = 3.6 Identities = 24/125 (19%), Positives = 58/125 (46%), Gaps = 13/125 (10%) Query: 1853 ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASR 1912 ++ L G++ RR ++L + EE+++ Q ++ +K ++ +R+ EAE A + Sbjct: 796 QKQLRGQIARRVYRQLLAEKREQEEKKK---QEEEEKKKREEEERERERERREAELRAQQ 852 Query: 1913 AQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEE 1972 + R++ + E ++ + RE+ + + V ++ RLE+ + + Sbjct: 853 EEETRKQQELEALQKSQKEAELTRELEKQKE----------NKQVEEILRLEKEIEDLQR 902 Query: 1973 AEEAQ 1977 +E Q Sbjct: 903 MKEQQ 907 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 460 bits (1184), Expect = e-129 Identities = 299/827 (36%), Positives = 445/827 (53%), Gaps = 49/827 (5%) Query: 108 EDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKKR 167 EDM +L L E +VL NL+ R+ LIYTY G V +NPY+ IY V+ Y G+ Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284 Query: 168 HEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKGRKE 227 E PPH++AV A+ ML +++Q I+ +GESG+GKTE TK +++YLA + + + Sbjct: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343 Query: 228 PGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLE 287 + ++L+A P+LE+FGNAKTV+NDNSSRFGKF+ I F G I GA YLLE Sbjct: 1344 -------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLE 1395 Query: 288 KSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS--SPGQERELF 345 KSR + QAK+E ++HIFY+LL G QL+ L+ Y +L G + + + + F Sbjct: 1396 KSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDF 1455 Query: 346 QETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQ--ATMPDNTAAQKLCRL 403 + L ++ VLGFS E+ S+ R+++++L GN+ ++ Q A++ Q + L Sbjct: 1456 RRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAEL 1515 Query: 404 LGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRAL 463 L + +A+ + R+ + T E A A +A+AK Y LF WL+ R+N + Sbjct: 1516 LQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALV 1575 Query: 464 DRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGI 523 SPRQ + ILDI GFE NSFEQLCINY NE LQ LFN +F EQEEY RE I Sbjct: 1576 --SPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQI 1633 Query: 524 PWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQ 583 W + F D QPCI+LI P G+L +LD++C FP+ATD +F++K G +P + Sbjct: 1634 DWQEITFA-DNQPCINLIS--LKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYS 1690 Query: 584 RPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG 643 +P+ +F++ HYAGKV Y+ +++L KN D + +V L +S R+ A ++ Sbjct: 1691 KPK--MPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSS--- 1745 Query: 644 IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKR 703 Q + G R TV +++SL L+ + NP F+RC+ PNH+K Sbjct: 1746 --HAPQAAPQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKE 1803 Query: 704 AGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMDGKQA 763 G EP +V+ QLR +GVLE +RI ++GFP R+ FQ F RY L A+ Sbjct: 1804 PGLFEPDVVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV--ALKHDLPANGDM 1861 Query: 764 CEKMIQAL-ELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRA 822 C ++ L ++ PN+YRVG SK+F + + LE R+ + ++ Q RG+ +R Sbjct: 1862 CVSVLSRLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRR 1921 Query: 823 FQKRQQQQSALRVMQRNCAAYL-KLRHWQWWRLFTKVKPLLQV---------TRQDEVLQ 872 F+ + + + ++Q YL + R+ Q R K + L+ R + Q Sbjct: 1922 FRSLRHK---IILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQ 1978 Query: 873 ARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAEL 919 L + +EL ++ VG L E A LA L+A A L Sbjct: 1979 VEGALLWEQEELSKREVVAVGHL--------EVPAELAGLLQAVAGL 2017 >gi|122937512 myosin VIIB [Homo sapiens] Length = 2116 Score = 459 bits (1182), Expect = e-129 Identities = 305/940 (32%), Positives = 491/940 (52%), Gaps = 67/940 (7%) Query: 99 MNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAI 158 M+P +DM L LNEA ++HNL RY IYTY+G V +NP++ LP+YT Sbjct: 59 MHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQ 118 Query: 159 VEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHV 218 V++Y + E+PPHV+A+ Y SM +++ DQ + +GESGAGKTE TK ++Q+LA + Sbjct: 119 VQLYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATI 178 Query: 219 ASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVG 278 + G +E+Q+L+ANPILEAFGNAKT++NDNSSRFGK+I I F+ +G I G Sbjct: 179 S---------GQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEG 229 Query: 279 ANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSP 338 A IE +LLEKSR RQA +E ++HIFY +L G + K L L S Y +LT G +S Sbjct: 230 ARIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSC 289 Query: 339 G--QERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRE--RNTDQATMPDN 394 + + + ++++L FS E ++++++A+L GN+ N D + + + Sbjct: 290 EGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMET 349 Query: 395 TAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRW 454 A + +LL + + L+ I + ++V ++ QA +A K Y LF W Sbjct: 350 PAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLW 409 Query: 455 LVLRLNRALDRSPRQGAS----FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTM 510 +V ++N A+ P Q +G+LDI GFE F+ NSFEQLCIN+ NE LQQ F + Sbjct: 410 IVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHV 469 Query: 511 FVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVE 570 F +EQEEY+ E I W ++ + D +P +DL+ P +++LLDEE FP+ TD + ++ Sbjct: 470 FTMEQEEYRSENISWDYIHY-TDNRPTLDLL--ALKPMSIISLLDEESRFPQGTDLTMLQ 526 Query: 571 KVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQST 630 K+ + F +P+++ D A F + H+AG+V Y+A +L KN D L+ ++ L++ S Sbjct: 527 KLNSVHANNKAFLQPKNIHD-ARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSK 585 Query: 631 DRLTAEIWK----DVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLS 686 ++ EI+ + + G + + G+ T+G +K+SL +LM L+ Sbjct: 586 NKFLREIFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILT 645 Query: 687 NTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYE 746 N P F+RCI PN K+ + L L QLR +G++E + I + GFP R F+EF QR+ Sbjct: 646 NCQPYFIRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFG 705 Query: 747 ILTPNAIPKGFMDGKQACEKMIQALELDPNL-YRVGQSKIFFRAGVLAQLEEERDLKVTD 805 +L PNA+ + I + L + ++ G++KIF R LE +R + Sbjct: 706 VLLPNAMRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDR 765 Query: 806 IIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRL-FTKVKPLLQ- 863 +S Q RGY R+ F ++++ L+ R Y R+++ + F +++ + + Sbjct: 766 AALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWR---GYCNRRNFKLILVGFERLQAIARS 822 Query: 864 --VTRQDEVLQARAQELQK------VQELQQQSAREVGELQGRVAQLEEERARLAEQLRA 915 + RQ + ++ R +LQ V++ Q R V +Q + R + A Sbjct: 823 QPLARQYQAMRQRTVQLQALCRGYLVRQQVQAKRRAVVVIQAHARGMAARRNFQQRKANA 882 Query: 916 EAELCAEAEETRGRLAARKQE-----------LELVVSELEARVGEEEECSRQMQTEKKR 964 + AE ++++G L A+K+ +E V L A +G +E Sbjct: 883 PLVIPAEGQKSQGALPAKKRRSIYDTVTDTEMVEKVFGFLPAMIGGQE------------ 930 Query: 965 LQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDL 1004 + H E E QKL + T ++ EED+ Sbjct: 931 -----GQASPHFEDLESKTQKLLEVDLDTVPMAEEPEEDV 965 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 456 bits (1173), Expect = e-127 Identities = 355/1152 (30%), Positives = 554/1152 (48%), Gaps = 114/1152 (9%) Query: 96 IQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYT 155 I+ M+P EDM L LNEA +L NL RY LIYTY+G V +NPY+ L IY+ Sbjct: 56 IKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYS 115 Query: 156 EAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYL 215 + Y KK E+PPH++A+ + Y +M ++ DQ + +GESGAGKTE+TK ++Q+L Sbjct: 116 PEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL 175 Query: 216 AHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGY 275 A ++ G +E+Q+L+A PILEAFGNAKT++NDNSSRFGK+I I+F+ G Sbjct: 176 AAIS---------GQHSWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGA 226 Query: 276 IVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPS 335 I GA IE YLLEKSR RQA DE ++H+FY +L G E K L L S Y +L G Sbjct: 227 IEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNC 286 Query: 336 -SSPGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRE--RNTDQATM 391 + G+ + + + +++VL F+ E + ++++A+L GN+ + N D + Sbjct: 287 ITCEGRVDSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEV 346 Query: 392 PDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERL 451 + + LL + D L + + + V ++EQA +A K Y RL Sbjct: 347 LFSPSLATAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRL 406 Query: 452 FRWLVLRLNRALDRSPRQGAS----FLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFN 507 F W+V ++N A+ + P Q +G+LDI GFE F +NSFEQLCIN+ NE LQQ F Sbjct: 407 FVWIVDKINAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFV 466 Query: 508 HTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKS 567 +F LEQEEY E I W ++F D Q +D+I P +++L+DEE FPK TD + Sbjct: 467 RHVFKLEQEEYDLESIDWLHIEF-TDNQDALDMIAN--KPMNIISLIDEESKFPKGTDTT 523 Query: 568 FVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLH 627 + K+ + + + P++ + F + H+AG V Y+ +L KN D L+ ++ L+H Sbjct: 524 MLHKLNSQHKLNANYIPPKN-NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVH 582 Query: 628 QSTDRLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKESLSRLMATLSN 687 S ++ +I++ D G R+ T+ +K SL LM TL Sbjct: 583 SSRNKFIKQIFQ--------------ADVAMGAETRKRS-PTLSSQFKRSLELLMRTLGA 627 Query: 688 TNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEI 747 P FVRCI PN K+ + L + QLR +G++E IRI R G+P R F EF +RY + Sbjct: 628 CQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRV 687 Query: 748 LTPNAIPKGFM-DGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDI 806 L P P D + C++M +A+ + +++G++KIF + LE ERD +TD Sbjct: 688 LLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDR 747 Query: 807 IVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTR 866 ++ Q RG+ R F K + AA L RHW+ K L+++ Sbjct: 748 VILLQKVIRGFKDRSNFLKLKN------------AATLIQRHWRGHNC-RKNYGLMRLGF 794 Query: 867 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 926 R Q L + ++L QQ + A+ R A + R A L +A Sbjct: 795 ------LRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAY-A 847 Query: 927 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKL 986 RG +A R + L A E + E+++L++ + +A EAE +++L Sbjct: 848 RGMIARRLHQ------RLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERL 901 Query: 987 -QLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKL 1045 QL + E ++K+ KE + L E +A E + Sbjct: 902 AQLAREDAERELKE----------------KEAARRKKELLEQMERARHEPVNHSDMVDK 945 Query: 1046 RLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRK 1105 + T + + + G ++LE+ +R + E + + ++ + E+L K Sbjct: 946 MFGFLGTSGGLPGQEGQAPSGFEDLERGRREMVEEDLDAALPLPDEDE--EDLSEYKFAK 1003 Query: 1106 ---------------EEELQAALARAEDEGGARAQL---------LKSLREAQ--AALAE 1139 L+ L +DEG A L + L E + A+++ Sbjct: 1004 FAATYFQGTTTHSYTRRPLKQPLLYHDDEGDQLAALAVWITILRFMGDLPEPKYHTAMSD 1063 Query: 1140 AQEDLE-SERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKK 1198 E + ++ T +K + EL+AL+GE E L + +R K + K Sbjct: 1064 GSEKIPVMTKIYETLGKKTYK---RELQALQGEGEAQLPEGQKKSSVRHKLVHLTLKKKS 1120 Query: 1199 TLEEET--RIHE 1208 L EE R+H+ Sbjct: 1121 KLTEEVTKRLHD 1132 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.313 0.129 0.348 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 70,708,054 Number of Sequences: 37866 Number of extensions: 3490923 Number of successful extensions: 78229 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 774 Number of HSP's successfully gapped in prelim test: 1664 Number of HSP's that attempted gapping in prelim test: 19036 Number of HSP's gapped (non-prelim): 18834 length of query: 1995 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1878 effective length of database: 13,817,196 effective search space: 25948694088 effective search space used: 25948694088 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.