Guide to the Human Genome
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Search of human proteins with 238624195

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo
sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo sapi...  1041   0.0  
gi|158262031 hypothetical protein LOC221545 isoform 1 [Homo sapi...   622   e-178
gi|238624193 hypothetical protein LOC221545 isoform 2 [Homo sapi...   332   5e-91
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ...    60   5e-09
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ...    60   5e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    58   2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    55   1e-07
gi|160707881 formin 2 [Homo sapiens]                                   53   6e-07
gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]            50   5e-06
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             49   8e-06
gi|164565408 common-site lymphoma/leukemia guanine nucleotide ex...    49   8e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  49   1e-05
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     48   2e-05
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     48   2e-05
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s...    45   1e-04
gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo s...    45   1e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     45   1e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    45   1e-04
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]             45   2e-04
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    44   3e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   3e-04
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    44   3e-04
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    44   4e-04
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    43   6e-04
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    43   8e-04
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               43   8e-04
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    42   0.001
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    42   0.001

>gi|238624195 hypothetical protein LOC221545 isoform 3 [Homo
           sapiens]
          Length = 496

 Score = 1041 bits (2693), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRH 60
           MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRH
Sbjct: 1   MYQPSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRH 60

Query: 61  PPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPR 120
           PPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPR
Sbjct: 61  PPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPR 120

Query: 121 LPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFG 180
           LPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFG
Sbjct: 121 LPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFG 180

Query: 181 PLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPR 240
           PLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPR
Sbjct: 181 PLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPR 240

Query: 241 LPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP 300
           LPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP
Sbjct: 241 LPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP 300

Query: 301 GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFI 360
           GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFI
Sbjct: 301 GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFI 360

Query: 361 NEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVH 420
           NEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVH
Sbjct: 361 NEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVH 420

Query: 421 LLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVA 480
           LLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVA
Sbjct: 421 LLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVA 480

Query: 481 LGLSEPEPDLNLCSKP 496
           LGLSEPEPDLNLCSKP
Sbjct: 481 LGLSEPEPDLNLCSKP 496


>gi|158262031 hypothetical protein LOC221545 isoform 1 [Homo
           sapiens]
          Length = 315

 Score =  622 bits (1605), Expect = e-178
 Identities = 296/314 (94%), Positives = 299/314 (95%), Gaps = 7/314 (2%)

Query: 190 HAPSRDGASRT-------PSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLP 242
           + PSR  A R         +  +DQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLP
Sbjct: 2   YQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLP 61

Query: 243 TQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGA 302
           TQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGA
Sbjct: 62  TQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGA 121

Query: 303 WIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFINE 362
           WIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFINE
Sbjct: 122 WIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFINE 181

Query: 363 ILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVHLL 422
           ILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVHLL
Sbjct: 182 ILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVHLL 241

Query: 423 FLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVALG 482
           FLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVALG
Sbjct: 242 FLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVALG 301

Query: 483 LSEPEPDLNLCSKP 496
           LSEPEPDLNLCSKP
Sbjct: 302 LSEPEPDLNLCSKP 315



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 24/24 (100%), Positives = 24/24 (100%)

Query: 1  MYQPSRGAARRLGPCLRAYQARPQ 24
          MYQPSRGAARRLGPCLRAYQARPQ
Sbjct: 1  MYQPSRGAARRLGPCLRAYQARPQ 24


>gi|238624193 hypothetical protein LOC221545 isoform 2 [Homo
           sapiens]
          Length = 181

 Score =  332 bits (851), Expect = 5e-91
 Identities = 158/160 (98%), Positives = 159/160 (99%)

Query: 337 RQELPKLFLQSHDYSLYSLDVEFINEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEV 396
           R +LPKLFLQSHDYSLYSLDVEFINEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEV
Sbjct: 22  RPQLPKLFLQSHDYSLYSLDVEFINEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEV 81

Query: 397 LQLTRHPENWTLQARWRLVGLPVHLLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHR 456
           LQLTRHPENWTLQARWRLVGLPVHLLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHR
Sbjct: 82  LQLTRHPENWTLQARWRLVGLPVHLLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHR 141

Query: 457 LDKLMPSHSPPTPVKKLLVGALVALGLSEPEPDLNLCSKP 496
           LDKLMPSHSPPTPVKKLLVGALVALGLSEPEPDLNLCSKP
Sbjct: 142 LDKLMPSHSPPTPVKKLLVGALVALGLSEPEPDLNLCSKP 181



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 24/25 (96%), Positives = 25/25 (100%)

Query: 1  MYQPSRGAARRLGPCLRAYQARPQV 25
          MYQPSRGAARRLGPCLRAYQARPQ+
Sbjct: 1  MYQPSRGAARRLGPCLRAYQARPQL 25


>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
           sapiens]
          Length = 647

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 66/198 (33%), Positives = 77/198 (38%), Gaps = 24/198 (12%)

Query: 8   AARRLGPCL--RAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLP 65
           AAR  G  L    +  RP+  GG   GR   GE P+     G   A G+A     P P  
Sbjct: 278 AARPCGAALPRSGFSGRPRGRGGAAAGRGSRGEHPAC----GVGLARGTA-----PQPAS 328

Query: 66  TCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAG---RVCVAPDSPRLP 122
           T AL    R G  G    R  A R   +   G R  R G G  A    RV   P   + P
Sbjct: 329 TWALAARPRAG--GTWTSRFEAQRG-CAHQDGQRRTRDGAGNHASEPARVWSPPPRRQRP 385

Query: 123 --VPRGDLKGRGREIRSPAAAPSRSSPAQTRPA----GRPQQPARLALGERSWQEGRPVC 176
             +PR  L+   +  R P A PS + PA+  PA    G P  P     G R   E  P  
Sbjct: 386 RRLPRASLQEEPKR-RPPCARPSGAGPAREGPAAWPGGAPTPPHARPTGRRQDPEPGPRA 444

Query: 177 TRFGPLRPGWQDGHAPSR 194
            R GP   GW  G A  R
Sbjct: 445 PRGGPASSGWHAGSAAGR 462


>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
           sapiens]
          Length = 647

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 66/198 (33%), Positives = 77/198 (38%), Gaps = 24/198 (12%)

Query: 8   AARRLGPCL--RAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLP 65
           AAR  G  L    +  RP+  GG   GR   GE P+     G   A G+A     P P  
Sbjct: 278 AARPCGAALPRSGFSGRPRGRGGAAAGRGSRGEHPAC----GVGLARGTA-----PQPAS 328

Query: 66  TCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAG---RVCVAPDSPRLP 122
           T AL    R G  G    R  A R   +   G R  R G G  A    RV   P   + P
Sbjct: 329 TWALAARPRAG--GTWTSRFEAQRG-CAHQDGQRRTRDGAGNHASEPARVWSPPPRRQRP 385

Query: 123 --VPRGDLKGRGREIRSPAAAPSRSSPAQTRPA----GRPQQPARLALGERSWQEGRPVC 176
             +PR  L+   +  R P A PS + PA+  PA    G P  P     G R   E  P  
Sbjct: 386 RRLPRASLQEEPKR-RPPCARPSGAGPAREGPAAWPGGAPTPPHARPTGRRQDPEPGPRA 444

Query: 177 TRFGPLRPGWQDGHAPSR 194
            R GP   GW  G A  R
Sbjct: 445 PRGGPASSGWHAGSAAGR 462


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 87/313 (27%), Positives = 113/313 (36%), Gaps = 32/313 (10%)

Query: 18  AYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGV 77
           A   R + +G E G  R         P  G  +++ SA       P P        R   
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA------RRRP 228

Query: 78  AGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRS 137
           +  GG +  A R+ +S    L +  R  G +A     AP  P  P P+G      + +R 
Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARS-GPSARGTPRAPAHPSQPKPKGL-----QALRP 282

Query: 138 PAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGA 197
           P   P R   A   PA  P   + LA    S      + ++  P  P      + +   A
Sbjct: 283 PQVTPPRKDAA---PALGPLSSSPLATPSPS----AALQSQAPPTLPATPHSSSLTCQLA 335

Query: 198 SRTPSGTEDQLYPG---TLPFPPLWPHSTTTTSPSSPLF-----WSPLPPRLP-TQRLPQ 248
           +  P        P    TLP PP  P S  TTS  SP       + P PP  P     PQ
Sbjct: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395

Query: 249 VPP-LPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQ 307
            PP L LP +QA  S     PP      P P+  +     L      PP P P    PF 
Sbjct: 396 APPALALPPLQAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFS 453

Query: 308 VPGTAHPSP-ATP 319
            P +   SP ATP
Sbjct: 454 PPASPPVSPSATP 466



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 89/356 (25%), Positives = 113/356 (31%), Gaps = 52/356 (14%)

Query: 4   PSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPP 63
           P  G  R  G   R   +RP  SG   G R    +  S  PV    RA G+ +    P P
Sbjct: 75  PRAGPTRSAGTSSRNPASRPPASG--RGERAPPAKNTSPGPVSSPGRASGTTR----PGP 128

Query: 64  LPTCALQ-------------RVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAG 110
           L    L+                +     AG RR  +     +  P +    R  G   G
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 111 RVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQ 170
               AP +   P   G  K            PS ++  +    G  Q+PA  +L   +  
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 171 EGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLP-----FPPLWPHSTT- 224
              P   R GP   G     AP+     + P G +    P   P      P L P S++ 
Sbjct: 249 LSSP--ARSGPSARG--TPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 225 --TTSPSSPLFWSPLPPRLP------------TQRLPQVPPLPL--PQIQALSSAWVVLP 268
             T SPS+ L  S  PP LP               LP  PP P   P +Q L S     P
Sbjct: 304 LATPSPSAAL-QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-----P 357

Query: 269 PGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPS 324
           P          L S  L    S    PP        P   P  A P    P   P+
Sbjct: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 70/274 (25%), Positives = 95/274 (34%), Gaps = 60/274 (21%)

Query: 118 SPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPA-------GRPQQPARLALGERSWQ 170
           +P  P P   ++       SP  +PS + P+Q  P+         P  PA   +   +  
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497

Query: 171 EGR-PVCTRFGPLRPGWQDGHAPSRDGASRTPS----GTEDQLYPGTLPFPP--LWPHST 223
             + P      PL+       AP    A  TP      +    +PG  PF P    P S 
Sbjct: 498 PPQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554

Query: 224 TTTSP--SSPLFWSPL------PPRLPTQRLPQVPPLPLPQIQA----LSSAWVVLPPGK 271
             T P  + P+  +PL      PP  PT + P+ PP P P        L+ A    PP  
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614

Query: 272 GEEGP-----GPEL--HSGCL----DGLRSLFEGP-------PCP-------YPGAWIPF 306
               P     GP+L  HS       + LR    GP       P P       +P AW   
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674

Query: 307 QVPGTAH------PSPATPSGDPSMEEHLSVMYE 334
             P  A       P P  P+  P   + L  +YE
Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 708



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 93/321 (28%), Positives = 111/321 (34%), Gaps = 92/321 (28%)

Query: 61  PPPLPTCALQRVDRLGVAGAGGRRCRACRA---RTSVLPGLRAVRRGQGQAAGRVCVAPD 117
           PPP  T A  RV  LG AGA GR+  A RA     + +P   A R G  ++AG       
Sbjct: 35  PPPPVTPAALRV--LGAAGAVGRKPLAERAGGIGGATIPE-SAPRAGPTRSAG------T 85

Query: 118 SPRLPVPRGDLKGRGREI-------RSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQ 170
           S R P  R    GRG            P ++P R+S   TRP    Q+  R++  E +  
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS-GTTRPGPLGQKGLRIS-AEETVA 143

Query: 171 EGRPVCTRFGPLRPGWQDGHAPSRDGASRTP-------------SGTEDQL---YPGTLP 214
            G+       P R     G    RD +  TP             +GTE  L    P   P
Sbjct: 144 RGK---ATEAPKRSALSAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198

Query: 215 FPP----------LWPHSTTTTSP----------------SSPLFWSPLPPRLP------ 242
            PP             HSTT  SP                S  L  S  P   P      
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 243 ---TQRLPQVPPLPLPQ-IQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCP 298
              T R P  P  P P+ +QAL    V  P        GP L S  L            P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPL----------ATP 307

Query: 299 YPGAWIPFQVPGTAHPSPATP 319
            P A +  Q P T    PATP
Sbjct: 308 SPSAALQSQAPPTL---PATP 325



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 66/219 (30%), Positives = 79/219 (36%), Gaps = 29/219 (13%)

Query: 138 PAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTR-----FGPLRPGWQDGHAP 192
           P A P+ + P    P   P  P    L   S Q    +        F P  P      AP
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP--PPSPPVQAP 451

Query: 193 SRDGASR--TPSGTEDQLYPGTLPFPPLW-PHSTTTTSPSSPLFWSP--LPPRL--PTQR 245
               AS   +PS T     P +L  PPL  P S   + P SP    P   PP L  P  +
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511

Query: 246 L----PQVPP-LPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP 300
           L    PQ PP L  P +QAL S      PG+    P   L       +  L   PP   P
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASF-PGQAPFSPSASL------PMSPLATPPPQAPP 564

Query: 301 GAWIP-FQVPGT--AHPSPATPSGDPSMEEHLSVMYERL 336
               P  QVP +  A P+   P   P+     SV   RL
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 60/218 (27%), Positives = 74/218 (33%), Gaps = 30/218 (13%)

Query: 115 APDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRP 174
           AP SP   +P   L         P A P  ++P    P   P  P   A   R      P
Sbjct: 542 APFSPSASLPMSPLA-----TPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGP 594

Query: 175 VCTRFGP-LRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLF 233
             +  GP L      G  P     SR+PS T        L  P L  HS++ TS    L 
Sbjct: 595 DTSVSGPRLTLALAPGPPPP---PSRSPSST--------LSGPDLAGHSSSATSTPEELR 643

Query: 234 WSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPG------PELHSGCLDG 287
                P       P  P   L      + +    PP      PG      P    G  DG
Sbjct: 644 GYDSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 702

Query: 288 LRSLFE--GPPC--PYPGAWIPFQVPGTAHPSPATPSG 321
           L +++E  GP    P PGA  P   PGT+    A  +G
Sbjct: 703 LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 740


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 85/310 (27%), Positives = 110/310 (35%), Gaps = 56/310 (18%)

Query: 18  AYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGV 77
           A   R + +G E G  R         P  G  +++ SA       P P        R   
Sbjct: 166 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA------RRRP 219

Query: 78  AGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRS 137
           +  GG +  A R+ +S    L +  R  G +A     AP  P  P P+G      + +R 
Sbjct: 220 SAGGGLQRPASRSLSSSATPLSSPARS-GPSARGTPRAPAHPSQPKPKGL-----QALRP 273

Query: 138 PAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGA 197
           P   P             P++ A  ALG  S     P+ T             +PS   +
Sbjct: 274 PQVTP-------------PRKDAAPALGPLS---SSPLATP------------SPSAPPS 305

Query: 198 SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLF-----WSPLPPRLP-TQRLPQVPP 251
              P   +      TLP PP  P S  TTS  SP       + P PP  P     PQ PP
Sbjct: 306 PSAPPSLQ------TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359

Query: 252 -LPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPG 310
            L LP +QA  S     PP      P P+  +     L      PP P P    PF  P 
Sbjct: 360 ALALPPLQAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPA 417

Query: 311 TAHPSP-ATP 319
           +   SP ATP
Sbjct: 418 SPPVSPSATP 427



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 96/394 (24%), Positives = 131/394 (33%), Gaps = 66/394 (16%)

Query: 4   PSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGER---PSSKPVRGAERALGSAQAQRH 60
           P + AA  LGP   +  A P  S           +    P + P   A  +LGS   Q  
Sbjct: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338

Query: 61  PPPLPTCALQRVDRLGVAGAGGRRCRACRARTS--VLPGLRAVRRGQGQAAGRVCV-APD 117
              LP+  L  +                +A  S    P L  +     QA   + V    
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 398

Query: 118 SPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPA-------GRPQQPARLALGERSWQ 170
           +P  P P   ++       SP  +PS + P+Q  P+         P  PA   +   +  
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458

Query: 171 EGR-PVCTRFGPLRPGWQDGHAPSRDGASRTPS----GTEDQLYPGTLPFPP--LWPHST 223
             + P      PL+       AP    A  TP      +    +PG  PF P    P S 
Sbjct: 459 PPQAPPPLAAPPLQLAKPPPQAPP---ALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515

Query: 224 TTTSP--SSPLFWSPL------PPRLPTQRLPQVPPLPLPQIQA----LSSAWVVLPPGK 271
             T P  + P+  +PL      PP  PT + P+ PP P P        L+ A    PP  
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575

Query: 272 GEEGP-----GPEL--HSGCL----DGLRSLFEGP-------PCP-------YPGAWIPF 306
               P     GP+L  HS       + LR    GP       P P       +P AW   
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635

Query: 307 QVPGTAH------PSPATPSGDPSMEEHLSVMYE 334
             P  A       P P  P+  P   + L  +YE
Sbjct: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 669



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 94/360 (26%), Positives = 118/360 (32%), Gaps = 50/360 (13%)

Query: 18  AYQARPQVSGGEE---GGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRV-- 72
           A + RP   GG +            P S P R    A G+ +A  HP       LQ +  
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 273

Query: 73  -----DRLGVAGAGGRRCRACRARTS--------VLPGLRAVRRGQGQAAGRVCVAPDSP 119
                 R   A A G    +  A  S          P L+ +         +   +  SP
Sbjct: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333

Query: 120 RLPVPRGDLKGRGREIRS---PAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVC 176
            L      L        +   P A P+ + P    P   P  P    L   S Q    + 
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393

Query: 177 TR-----FGPLRPGWQDGHAPSRDGASR--TPSGTEDQLYPGTLPFPPLW-PHSTTTTSP 228
                  F P  P      AP    AS   +PS T     P +L  PPL  P S   + P
Sbjct: 394 VHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 451

Query: 229 SSPLFWSP--LPPRL--PTQRL----PQVPP-LPLPQIQALSSAWVVLPPGKGEEGPGPE 279
            SP    P   PP L  P  +L    PQ PP L  P +QAL S      PG+    P   
Sbjct: 452 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF-PGQAPFSPSAS 510

Query: 280 LHSGCLDGLRSLFEGPPCPYPGAWIP-FQVPGT--AHPSPATPSGDPSMEEHLSVMYERL 336
           L       +  L   PP   P    P  QVP +  A P+   P   P+     SV   RL
Sbjct: 511 L------PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 85/311 (27%), Positives = 108/311 (34%), Gaps = 54/311 (17%)

Query: 61  PPPLPTCALQRVDRLGVAGAGGRRCRACRAR-------TSVLPGLRAVRRGQGQAAGRVC 113
           PPP  T A  RV  LG AGA GR+  A RA            P     R  +  A+GR  
Sbjct: 35  PPPPVTPAALRV--LGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGE 92

Query: 114 VAPDSPRLPVPRGDLKGRGREIRSPAAAP-----SRSSPAQTRPAGR-PQQPARLAL--G 165
            AP  P      G +   GR   +    P      R S  +T   G+  + P R AL  G
Sbjct: 93  RAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 150

Query: 166 ERSWQEG--------------RPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPG 211
            R    G              R   T  G  RP       P  +G  ++ S   +  +  
Sbjct: 151 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE--HST 208

Query: 212 TLPFPPL-----------WPHSTTTTSPSSPLFWSPL---PPRLPTQRLPQVPPLPLPQ- 256
           T P P              P S + +S ++PL  SP    P    T R P  P  P P+ 
Sbjct: 209 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLS-SPARSGPSARGTPRAPAHPSQPKPKG 267

Query: 257 IQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSP 316
           +QAL    V  P        GP   S       S    P  P     +P   P    PS 
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP--SPPATPPSQ 325

Query: 317 ATPS-GDPSME 326
           AT S G P+++
Sbjct: 326 ATTSLGSPTLQ 336



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 60/218 (27%), Positives = 74/218 (33%), Gaps = 30/218 (13%)

Query: 115 APDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRP 174
           AP SP   +P   L         P A P  ++P    P   P  P   A   R      P
Sbjct: 503 APFSPSASLPMSPLA-----TPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGP 555

Query: 175 VCTRFGP-LRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLF 233
             +  GP L      G  P     SR+PS T        L  P L  HS++ TS    L 
Sbjct: 556 DTSVSGPRLTLALAPGPPPP---PSRSPSST--------LSGPDLAGHSSSATSTPEELR 604

Query: 234 WSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPG------PELHSGCLDG 287
                P       P  P   L      + +    PP      PG      P    G  DG
Sbjct: 605 GYDSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663

Query: 288 LRSLFE--GPPC--PYPGAWIPFQVPGTAHPSPATPSG 321
           L +++E  GP    P PGA  P   PGT+    A  +G
Sbjct: 664 LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 701


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 53.1 bits (126), Expect = 6e-07
 Identities = 64/222 (28%), Positives = 75/222 (33%), Gaps = 32/222 (14%)

Query: 113  CVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEG 172
            C  P  P LP         G  +  P   P       T P+    QP  L        +G
Sbjct: 853  CNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPL--------QG 904

Query: 173  RPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGT-LPFPPLWPHSTTTTSPSSP 231
              +     P  PG      P   GA   P        PG  +P PP  P +     P  P
Sbjct: 905  TEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP----LPGAGIPPPPPLPGAAIPPPPPLP 960

Query: 232  LFWSPLPPRLPTQRLPQVPPLP---LPQIQALSSAWVVLP---PGKGEEGPGPELHSGCL 285
                PLPP LP   +P  PPLP   +P    L  A +  P   PG G   P P   +G  
Sbjct: 961  GAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI- 1019

Query: 286  DGLRSLFEGPPCPYPGAWIPFQVP----GTAHPSPATPSGDP 323
                     PP P PGA IP   P    G   P P   +G P
Sbjct: 1020 --------PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1053



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 40/121 (33%), Positives = 47/121 (38%), Gaps = 19/121 (15%)

Query: 210  PGT-LPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLP---LPQIQALSSAWV 265
            PG  +P PP  P +     P  P    P PP LP   +P  PPLP   +P    L    +
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1184

Query: 266  VLP---PGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGD 322
              P   PG G   P P   +G           PP P PG  IP   P  A P P   +G 
Sbjct: 1185 PPPPPLPGVGIPPPPPLPGAGI---------PPPPPLPGMGIP---PAPAPPLPPPGTGI 1232

Query: 323  P 323
            P
Sbjct: 1233 P 1233



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 43/127 (33%), Positives = 51/127 (40%), Gaps = 13/127 (10%)

Query: 210  PGT-LPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLP---LPQIQALSSAWV 265
            PG  +P PP  P +     P  P    P PP LP   +P  PPLP   +P    L  A +
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1074

Query: 266  VLP---PGKGEEGPGPELHSGC--LDGLRSLFEGPPCPYPGAWIPFQVP----GTAHPSP 316
              P   PG G   P P   +G      L  +   PP P PGA IP   P    G   P P
Sbjct: 1075 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1134

Query: 317  ATPSGDP 323
               +G P
Sbjct: 1135 LPGAGIP 1141



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 18/116 (15%)

Query: 210  PGT-LPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLP---LPQIQALSSAWV 265
            PG  +P PP  P +     P  P    P PP LP   +P  PPLP   +P    L  A +
Sbjct: 1037 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1096

Query: 266  VLPP---GKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWI--PFQVPGTAHPSP 316
              PP   G G   P P   +G           PP P PGA I  P  +PG   P P
Sbjct: 1097 PPPPPLPGVGIPPPPPLPGAGI---------PPPPPLPGAGIPPPPPLPGAGIPPP 1143



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 39/115 (33%), Positives = 46/115 (40%), Gaps = 16/115 (13%)

Query: 210  PGT-LPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLP---LPQIQALSSAWV 265
            PG  +P PP  P +     P  P    P PP LP   +P  PPLP   +P    L  A +
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140

Query: 266  VLPPGKGEEG--PGPELHSGCLDGLRSLFEGPPCPYPGAWI--PFQVPGTAHPSP 316
              PP     G  P P L    +         PP P PGA I  P  +PG   P P
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIP--------PPPPLPGAGIPPPPPLPGVGIPPP 1187


>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 84/303 (27%), Positives = 103/303 (33%), Gaps = 38/303 (12%)

Query: 40  PSSKPVR---GAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLP 96
           P   P+R   G  R  G  +A    P   +    R  R G    G RR    R R   LP
Sbjct: 28  PPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGG-LP 86

Query: 97  GLRAVRRGQGQAAGRVCVAPDSPRLPVP-------RGDLKGRGREIRSPAAAPSRSSPAQ 149
           G  A+  G  Q   R    P   R P+        R  L G     R P  A +   PA 
Sbjct: 87  GAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPAS 146

Query: 150 TRPAGRPQQP---ARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTED 206
             P  RP       RL L       G P      P    W+ G    R    + P     
Sbjct: 147 EAPGLRPDSARTRLRLRLASARLPRGLPP----APAAGLWRAGCTRLRPLLLQPP----P 198

Query: 207 QLYPGTLPFPPLWPHSTTTTSPS---SPLFWSPLPP--RLPTQRLPQVPPLPLPQIQALS 261
            L PG    P +  H+ T + P+   +P    P PP  R P+   P      L   +A +
Sbjct: 199 MLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPSAHSPAHTHFTLTLAEAHT 258

Query: 262 SAWVVLPPGKGEEGPGPELHSGCLDGLRSLFE--GPPCPYPGAWIPFQVPGTAHP-SPAT 318
            A +    G GE  PGP +  G  +   SL     PP P      P  VP TA   SP  
Sbjct: 259 RA-LTPARGGGEGDPGP-IVGGRPENEDSLASQTSPPAP------PAPVPSTARARSPGA 310

Query: 319 PSG 321
             G
Sbjct: 311 RRG 313


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 61/221 (27%), Positives = 73/221 (33%), Gaps = 48/221 (21%)

Query: 28  GEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPL-------PTCALQRVDRLGVA-- 78
           G  GGR G    P  KP   + R    A A    PP        P  A     R G A  
Sbjct: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381

Query: 79  GAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLK--------- 129
           GAG RR R  R R S        RRG+ +           PR   PRG  +         
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRR-----------PRPAPPRGSSRSLSRARSSS 430

Query: 130 --GRGREIRSPAAAP------------SRSSPAQTRPAGRPQQPARLALGERSWQEGRPV 175
             G GR    P   P            ++  P + RPA     P   A G R   EG+  
Sbjct: 431 DSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPG--AHGRRGGPEGKSS 488

Query: 176 CTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFP 216
               GP    W    +PS+   SR+ S  +    P   P P
Sbjct: 489 SRSPGPHPRSWSSSRSPSK---SRSRSAEKRPHSPSRSPSP 526



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 53/191 (27%), Positives = 71/191 (37%), Gaps = 15/191 (7%)

Query: 7   GAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRH------ 60
           GA RR     R  ++R   S     GRR    RP   P RG+ R+L  A++         
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRR----RPRPAPPRGSSRSLSRARSSSDSGSGRG 437

Query: 61  -PPPLPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRG-QGQAAGRVCVAPDS 118
            P P P    +R        A  R  RA  A TS  PG    R G +G+++ R    P  
Sbjct: 438 APGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSR-SPGPHP 496

Query: 119 PRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQ-PARLALGERSWQEGRPVCT 177
                 R   K R R       +PSR SP+  +P  R +    R    E      R    
Sbjct: 497 RSWSSSRSPSKSRSRSAEKRPHSPSR-SPSPKKPLSRDKDGEGRARHSEAEATRARRRSR 555

Query: 178 RFGPLRPGWQD 188
            + P+R   +D
Sbjct: 556 SYSPIRKRRRD 566



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 57/251 (22%), Positives = 88/251 (35%), Gaps = 63/251 (25%)

Query: 33  RRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRART 92
           ++GG  R   K    +E + GS+   R      +    R DR   + +G RR R  R+R+
Sbjct: 174 KKGGHRRSRKKRRLESECSCGSSSPLRKKKK--SVKKHRRDR---SDSGSRRKRRHRSRS 228

Query: 93  SVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRP 152
           S     +  R+ + +   R            P  +  GR     S     S  SP+ +  
Sbjct: 229 S-----KCKRKEKNKEKKR------------PHTESPGRRSHRHSSG---SSHSPSLSSH 268

Query: 153 AGRPQQPARLALGERSWQEGRPVCTRFG-----PLRPGWQDGHAPSRDGASRTPSGTEDQ 207
               + P+RL+   R   EGR   ++       P   G     +P R+G S   SG    
Sbjct: 269 YSDSRSPSRLSPKHRD--EGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGA--- 323

Query: 208 LYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVL 267
                        H     S  SP               P  P  P P+++  ++A    
Sbjct: 324 -------------HGGRPGSAHSP---------------PDKPSSPSPRVRDKAAAAAPT 355

Query: 268 PPGKGEEGPGP 278
           PP +G+E P P
Sbjct: 356 PPARGKESPSP 366


>gi|164565408 common-site lymphoma/leukemia guanine nucleotide
            exchange factor [Homo sapiens]
          Length = 1386

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 41/140 (29%), Positives = 56/140 (40%), Gaps = 19/140 (13%)

Query: 165  GERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRT----PSGTEDQLYPGTLPFPPLWP 220
            G R  Q   PVC++  P++P    G +    G   T    P    D   PGT P P    
Sbjct: 1060 GSRDVQGPDPVCSQ--PIQPLSWHGSSLDPQGPGDTLPPLPCHLPDLQIPGTSPLPAHGS 1117

Query: 221  HSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPEL 280
            H       ++PL    L   LP  ++P   PLPLPQ+  L+  WV   P   ++G  P++
Sbjct: 1118 HLDHRIPANAPL---SLSQELPDTQVPATTPLPLPQV--LTDIWVQALPTSPKQGSLPDI 1172

Query: 281  HSGCLDGLRSLFEGPPCPYP 300
                          PP P P
Sbjct: 1173 QGPA--------AAPPLPEP 1184



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 28/77 (36%), Positives = 34/77 (44%), Gaps = 10/77 (12%)

Query: 96  PGLRAVRRGQGQAAGRVC---VAPDSPRLPVPRG-----DLKGRGREIRSPAAAPSRSSP 147
           P L   RRG+    G VC    AP +P +  PRG      L   G E   PA  P+ +  
Sbjct: 15  PSLGCGRRGEVCDCGTVCETRTAPAAPTMASPRGSGSSTSLSTVGSE-GDPAPGPTPACS 73

Query: 148 AQTRPAGRPQQPARLAL 164
           A +RP   P  P RL L
Sbjct: 74  A-SRPEPLPGPPIRLHL 89



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 31/115 (26%), Positives = 39/115 (33%), Gaps = 18/115 (15%)

Query: 5    SRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPL 64
            S+  ARR GP            GG     RG     SS P   A     S   Q  PPP 
Sbjct: 1287 SQSLARRQGP-----------GGGAPAASRGSW---SSAPTSRAS----SPPPQPQPPPP 1328

Query: 65   PTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSP 119
            P   L     + +   GG R R  +A+  +          +     R   APD+P
Sbjct: 1329 PARRLSYATTVNIHVGGGGRLRPAKAQVRLNHPALLASTQESMGLHRAQGAPDAP 1383


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 83/345 (24%), Positives = 111/345 (32%), Gaps = 63/345 (18%)

Query: 3    QPSRGAARRLGPCLRAYQARPQVSGGEEGGRR-----------GGGERPSSKPVRGAERA 51
            +P  G       C RA      V  G  G  +           GGG R + +P  G    
Sbjct: 971  EPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEG---- 1026

Query: 52   LGSAQAQRHPPPLPTC--------ALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAV-R 102
                    HP P P           L  V      G GG      R  +  + GL A  R
Sbjct: 1027 --------HPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATAR 1078

Query: 103  RGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRP--QQPA 160
            RG G++A       D      PRG  KG       P A    S+  + R   +   Q+  
Sbjct: 1079 RGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENV 1138

Query: 161  RLALGERSWQEGRPVCTR--FGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPL 218
            +  L E    + RP       GP  P     +        R P+   +Q  P  LP PP 
Sbjct: 1139 KFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPAS--EQAGPPELPPPP- 1195

Query: 219  WPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGP 278
                     P+ P          P   L  +PPLP P+ +A   A   + P      P P
Sbjct: 1196 --------PPAEP----------PPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVP 1237

Query: 279  ELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDP 323
            +L        + +    P P PG+    +  GT  P P +P   P
Sbjct: 1238 KLQGSPTPTSKKV----PLPGPGSPEVKRAHGT--PPPVSPKPPP 1276



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 79/299 (26%), Positives = 96/299 (32%), Gaps = 67/299 (22%)

Query: 46  RGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACRART----SVLPGLRAV 101
           R A ++L     +  PPP PT A                C++ +  T     +   L+A 
Sbjct: 620 RKAPQSLEVMAIESPPPPEPTPA---------------DCQSPKMTTFQDSELSDELQAA 664

Query: 102 RRGQGQAAGRVCVAPDSPRLPVPRG------DLKGRGREIRSPAAAPSRSSPAQTRPAGR 155
             G  +  G     P S   P PR        L GR R + S         P  + P  R
Sbjct: 665 MTGPAEV-GPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSR 723

Query: 156 PQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPF 215
            Q        E    EG    T     RPG + GH+  R      P      L PGT  F
Sbjct: 724 SQ--------EYLLDEGPAPGTPPREARPG-RHGHSIKRASVPPVPGKPRQVLPPGTSHF 774

Query: 216 PPLWPHSTTTTSPSSPLFW-------------SPLPPRLPTQRLPQVPPLPLPQIQALSS 262
            P  P + T T P SP                 P P  LP    P + P  LPQ      
Sbjct: 775 TP--PQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERP-MSPRSLPQSPTHRG 831

Query: 263 AWVVLP-PGKGEEGPGPELHSGCLDGLRSLFEGP-PCPYPGAWIPFQVPGTAHPSPATP 319
              VLP P +GE GP                 GP P P P A     +P  A   P  P
Sbjct: 832 FAYVLPQPVEGEVGPAA--------------PGPAPPPVPTAVPTLCLPPEADAEPGRP 876


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 66/215 (30%), Positives = 78/215 (36%), Gaps = 36/215 (16%)

Query: 108 AAGRVCVAPDSP-RLPVPRGD-LKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALG 165
           +A  + V P  P R PVP    L G    I  P  AP  S+     P   P  P  L  G
Sbjct: 557 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP-LPGG 615

Query: 166 ERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTT 225
                    VC    P  PG            S  P  + D     T+P PP  P     
Sbjct: 616 ---------VCISSPPSLPGGT--------AISPPPPLSGD----ATIPPPPPLPEGVGI 654

Query: 226 TSPSSPLFWSPLPPRLP---TQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHS 282
            SPSS    + +PP  P   + R+P  PP PLP    +      LP   G   P P L  
Sbjct: 655 PSPSSLPGGTAIPPPPPLPGSARIPPPPP-PLPGSAGIPPPPPPLPGEAGMPPPPPPLPG 713

Query: 283 GCLDGLRSLFEGPPCPYPGA-WIPFQVPGTAHPSP 316
           G   G+      PP P+PG   IP   PG   P P
Sbjct: 714 G--PGI-----PPPPPFPGGPGIPPPPPGMGMPPP 741


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 66/215 (30%), Positives = 78/215 (36%), Gaps = 36/215 (16%)

Query: 108 AAGRVCVAPDSP-RLPVPRGD-LKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALG 165
           +A  + V P  P R PVP    L G    I  P  AP  S+     P   P  P  L  G
Sbjct: 566 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP-LPGG 624

Query: 166 ERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTT 225
                    VC    P  PG            S  P  + D     T+P PP  P     
Sbjct: 625 ---------VCISSPPSLPGGT--------AISPPPPLSGD----ATIPPPPPLPEGVGI 663

Query: 226 TSPSSPLFWSPLPPRLP---TQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHS 282
            SPSS    + +PP  P   + R+P  PP PLP    +      LP   G   P P L  
Sbjct: 664 PSPSSLPGGTAIPPPPPLPGSARIPPPPP-PLPGSAGIPPPPPPLPGEAGMPPPPPPLPG 722

Query: 283 GCLDGLRSLFEGPPCPYPGA-WIPFQVPGTAHPSP 316
           G   G+      PP P+PG   IP   PG   P P
Sbjct: 723 G--PGI-----PPPPPFPGGPGIPPPPPGMGMPPP 750


>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
           sapiens]
          Length = 1074

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 68/262 (25%), Positives = 92/262 (35%), Gaps = 78/262 (29%)

Query: 103 RGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGR------- 155
           RGQG    R   +P++  LP+ R   +GRG  +R PA+   R    + R A R       
Sbjct: 98  RGQGP---RPQTSPET--LPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPI 152

Query: 156 ----------------------PQQPARLAL------GERSWQEGRPVCTRFG------- 180
                                 P+ P R  L      GE +     P    F        
Sbjct: 153 KPGMFGYGRVPFALPLHRNRRHPRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQT 212

Query: 181 PLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPH---STTTTSPSSP------ 231
            L P     H PS      +P   + ++ P T P  PL  H     + T P SP      
Sbjct: 213 ELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRP-APLRHHPRAQASGTEPPSPTHSLGE 271

Query: 232 --LFWSPLPPRLPTQR---LPQVP---PLPLPQIQALSSAWVVLPPGKGEEGPGPELHSG 283
              F +   PR P+ +    PQV    P P P +          P G+G++G GP    G
Sbjct: 272 GGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSV----------PRGRGQQGQGPWGTGG 321

Query: 284 CLDGLRSLFEGPPCPYPGAWIP 305
              G R     P   +PGAW+P
Sbjct: 322 TPHGPRL---EPDPQHPGAWLP 340


>gi|56788359 thrombospondin repeat containing 1 isoform 2 [Homo
           sapiens]
          Length = 877

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 68/262 (25%), Positives = 92/262 (35%), Gaps = 78/262 (29%)

Query: 103 RGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGR------- 155
           RGQG    R   +P++  LP+ R   +GRG  +R PA+   R    + R A R       
Sbjct: 98  RGQGP---RPQTSPET--LPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPI 152

Query: 156 ----------------------PQQPARLAL------GERSWQEGRPVCTRFG------- 180
                                 P+ P R  L      GE +     P    F        
Sbjct: 153 KPGMFGYGRVPFALPLHRNRRHPRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQT 212

Query: 181 PLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPH---STTTTSPSSP------ 231
            L P     H PS      +P   + ++ P T P  PL  H     + T P SP      
Sbjct: 213 ELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRP-APLRHHPRAQASGTEPPSPTHSLGE 271

Query: 232 --LFWSPLPPRLPTQR---LPQVP---PLPLPQIQALSSAWVVLPPGKGEEGPGPELHSG 283
              F +   PR P+ +    PQV    P P P +          P G+G++G GP    G
Sbjct: 272 GGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSV----------PRGRGQQGQGPWGTGG 321

Query: 284 CLDGLRSLFEGPPCPYPGAWIP 305
              G R     P   +PGAW+P
Sbjct: 322 TPHGPRL---EPDPQHPGAWLP 340


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 58/228 (25%), Positives = 77/228 (33%), Gaps = 33/228 (14%)

Query: 30  EGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACR 89
           +GG +  G  P  KP     +    +Q+ R PP  P          G    GG + +   
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ---------GPPPQGGNQPQG-- 255

Query: 90  ARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSP-A 148
                 PG       QG    +    P  P+ P P+G  K R    RSP   P    P  
Sbjct: 256 --PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS--RSPPGKPQGPPPQG 311

Query: 149 QTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAP---SRDGASRTPSGTE 205
             +P G P  P +   G       +P     GP  PG   G  P   S+  ++R+P G  
Sbjct: 312 GNQPQGPPPPPGK-PQGPPPQGGNKPQ----GPPPPGKPQGPPPQGGSKSRSARSPPGK- 365

Query: 206 DQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLP 253
                   P  P          P  P   +P  P+ P    PQ PP P
Sbjct: 366 --------PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 405



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 78/304 (25%), Positives = 105/304 (34%), Gaps = 52/304 (17%)

Query: 30  EGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACR 89
           +GG +  G  P  KP     +    +++ R PP  P          G    GG + +   
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ---------GPPPQGGNQPQG-- 193

Query: 90  ARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSP-A 148
                 PG       QG    +    P  P+ P P+GD   + +  RSP   P    P  
Sbjct: 194 --PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD--NKSQSARSPPGKPQGPPPQG 249

Query: 149 QTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAP---SRDGASRTPSG-- 203
             +P G P  P +   G       +P     GP  PG   G  P   S+  +SR+P G  
Sbjct: 250 GNQPQGPPPPPGK-PQGPPPQGGNKPQ----GPPPPGKPQGPPPQGGSKSRSSRSPPGKP 304

Query: 204 ----TEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQA 259
                +    P   P PP  P        + P    P PP       PQ PP   PQ  +
Sbjct: 305 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP--QGPPPP-----GKPQGPP---PQGGS 354

Query: 260 LSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPS--PA 317
            S +    PPGK +  P  E ++          +GPP P  G     Q P    P   P 
Sbjct: 355 KSRS-ARSPPGKPQGPPQQEGNNP---------QGPPPPAGGNPQQPQAPPAGQPQGPPR 404

Query: 318 TPSG 321
            P G
Sbjct: 405 PPQG 408



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 44/165 (26%), Positives = 57/165 (34%), Gaps = 20/165 (12%)

Query: 30  EGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACR 89
           +GG +  G  P  KP     +    +++ R PP  P          G    GG + +   
Sbjct: 269 QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQ---------GPPPQGGNQPQG-- 317

Query: 90  ARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQ 149
                 PG       QG    +    P  P+ P P+G  K R    RSP   P    P Q
Sbjct: 318 --PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSA--RSPPGKPQ--GPPQ 371

Query: 150 TRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSR 194
            +    PQ P   A G     +  P     GP RP    G  PSR
Sbjct: 372 -QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP--PQGGRPSR 413


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 61/249 (24%), Positives = 78/249 (31%), Gaps = 28/249 (11%)

Query: 79  GAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAP----DSPRLPVPRGDLKGRGRE 134
           G GG   R        L   R+   G G    R  + P      P+ P+P        ++
Sbjct: 12  GGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPP--PHQQQ 69

Query: 135 IRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSR 194
            + P   P    P   +P   PQ   +           +PV  +     PG       S 
Sbjct: 70  QQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASS 129

Query: 195 DGASRTP--SGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPL 252
                TP  SG      PG  P P   P + T+  P +P      PP  P+  +P  PP 
Sbjct: 130 SAPPATPPTSGAPPGSGPGPTPTP---PPAVTSAPPGAP------PPTPPSSGVPTTPP- 179

Query: 253 PLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTA 312
                     A    PP     GPGP    G   G     + P  P PG       PG  
Sbjct: 180 ---------QAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPG-G 229

Query: 313 HPSPATPSG 321
           HP P    G
Sbjct: 230 HPKPPHRGG 238


>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 87/337 (25%), Positives = 114/337 (33%), Gaps = 58/337 (17%)

Query: 15  CLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPP------PLPTCA 68
           C R     P    G E  RR   +R           AL SA  Q+  P      P P   
Sbjct: 57  CGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSG 116

Query: 69  LQRVDR--LGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRG 126
           ++   R  +G++ A GR   AC AR     G+R V             +P  P  P+P  
Sbjct: 117 VRPPPRGRVGLSQAPGRPLGAC-ARAK---GIRLVNP-----------SPPRPPEPIPAS 161

Query: 127 DLKGRGREIRSPAAA----PSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPL 182
                G   R P  +    P +   +  R    P+   R+A      +   P C     L
Sbjct: 162 AAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGL 221

Query: 183 RPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPF----PPLWPHSTTTTSPSSPL--FWSP 236
                  HA       R    T  +  P T  F    P   P   T++S S+PL  FWSP
Sbjct: 222 SVPTPPEHA-----GGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276

Query: 237 LPPRLPTQR-LPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGP 295
           L  R P+ R  P    L L ++          PP     G      SG     R+L   P
Sbjct: 277 L--RNPSPRPAPACGELRLGRLS---------PPRADTGGSSSGGCSGPDSKHRTL---P 322

Query: 296 PCPYPGAWIPFQVPGTAHPS-----PATPSGDPSMEE 327
             P P AW     PG  +P+     P    G PS  +
Sbjct: 323 APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRD 359


>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 87/337 (25%), Positives = 114/337 (33%), Gaps = 58/337 (17%)

Query: 15  CLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPP------PLPTCA 68
           C R     P    G E  RR   +R           AL SA  Q+  P      P P   
Sbjct: 57  CGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSG 116

Query: 69  LQRVDR--LGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRG 126
           ++   R  +G++ A GR   AC AR     G+R V             +P  P  P+P  
Sbjct: 117 VRPPPRGRVGLSQAPGRPLGAC-ARAK---GIRLVNP-----------SPPRPPEPIPAS 161

Query: 127 DLKGRGREIRSPAAA----PSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPL 182
                G   R P  +    P +   +  R    P+   R+A      +   P C     L
Sbjct: 162 AAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGL 221

Query: 183 RPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPF----PPLWPHSTTTTSPSSPL--FWSP 236
                  HA       R    T  +  P T  F    P   P   T++S S+PL  FWSP
Sbjct: 222 SVPTPPEHA-----GGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276

Query: 237 LPPRLPTQR-LPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGP 295
           L  R P+ R  P    L L ++          PP     G      SG     R+L   P
Sbjct: 277 L--RNPSPRPAPACGELRLGRLS---------PPRADTGGSSSGGCSGPDSKHRTL---P 322

Query: 296 PCPYPGAWIPFQVPGTAHPS-----PATPSGDPSMEE 327
             P P AW     PG  +P+     P    G PS  +
Sbjct: 323 APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRD 359


>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 87/337 (25%), Positives = 114/337 (33%), Gaps = 58/337 (17%)

Query: 15  CLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPP------PLPTCA 68
           C R     P    G E  RR   +R           AL SA  Q+  P      P P   
Sbjct: 57  CGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSG 116

Query: 69  LQRVDR--LGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRG 126
           ++   R  +G++ A GR   AC AR     G+R V             +P  P  P+P  
Sbjct: 117 VRPPPRGRVGLSQAPGRPLGAC-ARAK---GIRLVNP-----------SPPRPPEPIPAS 161

Query: 127 DLKGRGREIRSPAAA----PSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPL 182
                G   R P  +    P +   +  R    P+   R+A      +   P C     L
Sbjct: 162 AAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGL 221

Query: 183 RPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPF----PPLWPHSTTTTSPSSPL--FWSP 236
                  HA       R    T  +  P T  F    P   P   T++S S+PL  FWSP
Sbjct: 222 SVPTPPEHA-----GGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276

Query: 237 LPPRLPTQR-LPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGP 295
           L  R P+ R  P    L L ++          PP     G      SG     R+L   P
Sbjct: 277 L--RNPSPRPAPACGELRLGRLS---------PPRADTGGSSSGGCSGPDSKHRTL---P 322

Query: 296 PCPYPGAWIPFQVPGTAHPS-----PATPSGDPSMEE 327
             P P AW     PG  +P+     P    G PS  +
Sbjct: 323 APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRD 359


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 45/139 (32%), Positives = 54/139 (38%), Gaps = 11/139 (7%)

Query: 188 DGHAPSRDGASRT--PSGTEDQ-LYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQ 244
           +G A    G+SR   P G   +  +PG +P    +P       P  P      PPR P  
Sbjct: 183 EGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLG 242

Query: 245 RL-PQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDG---LRSLFEGPPCPYP 300
              P  PP P P  Q L    +  PP +G+  P P L  G   G   L  L  GPP P P
Sbjct: 243 PPGPPGPPGPPPPGQVLPPP-LAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVP 301

Query: 301 GAWIPFQVPGTAHPSPATP 319
           G   P   PG   P    P
Sbjct: 302 GYGPP---PGPPPPQQGPP 317


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 81/326 (24%), Positives = 112/326 (34%), Gaps = 49/326 (15%)

Query: 29  EEGGRRGGGERPSSKPVRGAERALG------------SAQAQRHPP-----PLPTCALQR 71
           E  G  GG   P S P  G  R+ G            S + +R PP     P P  +  R
Sbjct: 60  ERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119

Query: 72  VDRLGVAGAGGRRCRACRARTSVLPG--LRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLK 129
                  G  G++     A  +V  G    A +R    A  R   +  +P  P P    +
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179

Query: 130 GR--GREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQ 187
            R  G E+  P  APS    A+ RP     + +  +  E S  E  P   R  P   G  
Sbjct: 180 SRAAGTEVGLPRPAPS----ARPRPPTEGPRKSVSSASEHSTTEPSPAARR-RPSAGGGL 234

Query: 188 DGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLP 247
              A     +S TP  +  +  P             T  +P+ P    P P  L   R P
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSA---------RGTPRAPAHPS--QPKPKGLQALRPP 283

Query: 248 QVPPL---PLPQIQALSSAWVVLPPGKGEEG-PGPELHSGCLDGLRSLFEGPPCPYPGAW 303
           QV P      P +  LSS+ +  P   G +  P P   +       +L   PP   P   
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP--- 340

Query: 304 IPFQVPGTAHPS-----PATPSGDPS 324
           +P   P  + P      P+ P+  PS
Sbjct: 341 LPLAPPSPSAPPSLQTLPSPPATPPS 366



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 80/334 (23%), Positives = 107/334 (32%), Gaps = 53/334 (15%)

Query: 4   PSRGAARRLGPCLRAYQARPQVSGGEEGGRRGGGERPSSKPVRGAERALGSAQAQRHPPP 63
           P  G  R  G   R   +RP  SG   G R    +  S  PV    RA G+ +    P P
Sbjct: 75  PRAGPTRSAGTSSRNPASRPPASG--RGERAPPAKNTSPGPVSSPGRASGTTR----PGP 128

Query: 64  LPTCALQ-------------RVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAG 110
           L    L+                +     AG RR  +     +  P +    R  G   G
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 111 RVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQ 170
               AP +   P   G  K            PS ++  +    G  Q+PA  +L   +  
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 171 EGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLP-----FPPLWPHSTTT 225
              P   R GP   G     AP+     + P G +    P   P      P L P S++ 
Sbjct: 249 LSSP--ARSGPSARG--TPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 226 TSPSSPL------------FWSPLPPRLP-----TQRLPQVPPLPL--PQIQALSSAWVV 266
            +  SP               +PLP  LP        LP  PP P   P +Q L S    
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS---- 359

Query: 267 LPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYP 300
            PP        P + +  +    SL   PP   P
Sbjct: 360 -PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 69/244 (28%), Positives = 87/244 (35%), Gaps = 52/244 (21%)

Query: 137 SPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPL-RPGWQDGHAPSRD 195
           SP A+P  S P+ T P   P+ P  LA          P      PL +P  Q   A +  
Sbjct: 740 SPPASPPMS-PSATPP---PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795

Query: 196 GASRTPSGTEDQLYPGTLPFPPL--WPHSTTTTSP--SSPLFWSPL------PPRLPTQR 245
                PS      +PG  PF P    P S   T P  + P+  +PL      PP  PT +
Sbjct: 796 PLQALPSPPAS--FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853

Query: 246 LPQVPPLPLPQIQA----LSSAWVVLPPGKGEEGP-----GPEL--HSGCL----DGLRS 290
            P+ PP P P        L+ A    PP      P     GP+L  HS       + LR 
Sbjct: 854 APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913

Query: 291 LFEGP-------PCP-------YPGAWIPFQVPGTAH------PSPATPSGDPSMEEHLS 330
              GP       P P       +P AW     P  A       P P  P+  P   + L 
Sbjct: 914 YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 973

Query: 331 VMYE 334
            +YE
Sbjct: 974 TIYE 977



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 89/381 (23%), Positives = 119/381 (31%), Gaps = 96/381 (25%)

Query: 18  AYQARPQVSGGEE---GGRRGGGERPSSKPVRGAERALGSAQAQRHP------------- 61
           A + RP   GG +            P S P R    A G+ +A  HP             
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282

Query: 62  ----PP----LPTCALQRVDRLGVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVC 113
               PP     P         L      G + R      +    L A        A  + 
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP 342

Query: 114 VAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGR 173
           +AP SP  P     L         PA  PS++ P+ T P   P Q         S Q   
Sbjct: 343 LAPPSPSAPPSLQTLPS------PPATPPSQAPPSMTTP---PMQ------APPSLQTIP 387

Query: 174 PVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHST---------- 223
           P+        P  Q   +P    + +  +         T  F  + P  T          
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 224 TTTSPSSPLFWSPLP----PRLPTQRLPQVPPLPLP----QIQALSS----------AWV 265
            +T P SP   +PL     P L T   P V PL  P     +QALSS          + +
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507

Query: 266 VLPPGKGE--------EGPGPELHSGCLDGLRSL----------------FEGPPCPYPG 301
           ++PP + +        + P   L +  L+ L SL                 E PPCP P 
Sbjct: 508 IMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP- 566

Query: 302 AWIPFQVPGT--AHPSPATPS 320
              P Q P +    P P TPS
Sbjct: 567 --CPLQAPPSPLTTPPPETPS 585



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 96/339 (28%), Positives = 118/339 (34%), Gaps = 91/339 (26%)

Query: 61  PPPLPTCALQRVDRLGVAGAGGRRCRACRA---RTSVLPGLRAVRRGQGQAAGRVCVAPD 117
           PPP  T A  RV  LG AGA GR+  A RA     + +P   A R G  ++AG       
Sbjct: 35  PPPPVTPAALRV--LGAAGAVGRKPLAERAGGIGGATIPE-SAPRAGPTRSAG------T 85

Query: 118 SPRLPVPRGDLKGRGREI-------RSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQ 170
           S R P  R    GRG            P ++P R+S   TRP    Q+  R++  E +  
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS-GTTRPGPLGQKGLRIS-AEETVA 143

Query: 171 EGRPVCTRFGPLRPGWQDGHAPSRDGASRTP-------------SGTEDQL---YPGTLP 214
            G+       P R     G    RD +  TP             +GTE  L    P   P
Sbjct: 144 RGK---ATEAPKRSALSAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198

Query: 215 FPP----------LWPHSTTTTSP----------------SSPLFWSPLPPRLP------ 242
            PP             HSTT  SP                S  L  S  P   P      
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 243 ---TQRLPQVPPLPLPQ-IQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCP 298
              T R P  P  P P+ +QAL    V  P        GP   S       S  +  P P
Sbjct: 259 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318

Query: 299 YP-GAWIPFQVPGTAHPS----------PATPSGDPSME 326
            P  A  P  +P T  PS          P +PS  PS++
Sbjct: 319 PPDNAATP--LPATLPPSPPLATPLPLAPPSPSAPPSLQ 355



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 65/228 (28%), Positives = 81/228 (35%), Gaps = 27/228 (11%)

Query: 118 SPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRP--AGRPQQ--PARLALGERSWQEGR 173
           +P  P P   ++       SP  +PS + P+Q  P  A  P Q  P+  A    S     
Sbjct: 663 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722

Query: 174 PVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLW-PHSTTTTSPSSPL 232
           P         P  Q   +P       +PS T     P  L  PPL  P S   + P SPL
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPA-SPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL 781

Query: 233 FWSPLPPRLPTQRLPQVPP-LPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSL 291
              P          PQ PP L  P +QAL S      PG+    P   L       +  L
Sbjct: 782 AKPP----------PQAPPALATPPLQALPSPPASF-PGQAPFSPSASL------PMSPL 824

Query: 292 FEGPPCPYPGAWIP-FQVPGT--AHPSPATPSGDPSMEEHLSVMYERL 336
              PP   P    P  QVP +  A P+   P   P+     SV   RL
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 872



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 57/212 (26%), Positives = 72/212 (33%), Gaps = 33/212 (15%)

Query: 138 PAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTR-----FGPLRPGWQDGHAP 192
           P A P  + P    P   P  P    L   S Q    +        F P  P      AP
Sbjct: 619 PQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP--PPSPPVQAP 676

Query: 193 SRDGASR--TPSGTEDQLYPGTLPFPPLW-PHSTTTTSPSSPLFWSP--LPPRL--PTQR 245
               AS   +PS T     P +L  PPL  P S   + P SP    P   PP L  P  +
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736

Query: 246 LPQVPP---------LPLPQIQALSSA-WVVLPPGKGEE-------GPGPELHSGCLDGL 288
           +P  PP          P P++  L +A  + +PP             P P+         
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796

Query: 289 RSLFEGPPCPYPGAWIPFQVPGTAHPSP-ATP 319
                 PP  +PG   PF    +   SP ATP
Sbjct: 797 LQALPSPPASFPGQ-APFSPSASLPMSPLATP 827



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/122 (30%), Positives = 45/122 (36%), Gaps = 17/122 (13%)

Query: 210 PGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPP 269
           P T P PP  P S  T  P +P    P     P Q LP  P  PL      +   + LPP
Sbjct: 575 PLTTP-PPETPSSIATPPPQAP----PALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629

Query: 270 GKGEEGP--GPELHSGCLDGLRS-------LFEGP--PCPYPGAWIPFQVPGTAHPSP-A 317
            +    P   P L        ++       L + P  P P P    PF  P +   SP A
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689

Query: 318 TP 319
           TP
Sbjct: 690 TP 691



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 60/218 (27%), Positives = 74/218 (33%), Gaps = 30/218 (13%)

Query: 115  APDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRP 174
            AP SP   +P   L         P A P  ++P    P   P  P   A   R      P
Sbjct: 811  APFSPSASLPMSPLA-----TPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGP 863

Query: 175  VCTRFGP-LRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLF 233
              +  GP L      G  P     SR+PS T        L  P L  HS++ TS    L 
Sbjct: 864  DTSVSGPRLTLALAPGPPPP---PSRSPSST--------LSGPDLAGHSSSATSTPEELR 912

Query: 234  WSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPG------PELHSGCLDG 287
                 P       P  P   L      + +    PP      PG      P    G  DG
Sbjct: 913  GYDSGPEGGAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971

Query: 288  LRSLFE--GPPC--PYPGAWIPFQVPGTAHPSPATPSG 321
            L +++E  GP    P PGA  P   PGT+    A  +G
Sbjct: 972  LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 1009


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 60/239 (25%), Positives = 79/239 (33%), Gaps = 32/239 (13%)

Query: 20  QARPQVSGGEEGGRRGGGERPSSKPVRGAERAL----GSAQAQRHPPPLPTCALQRVDRL 75
           Q  P   G  +G    GG RP   P  G  +        +++ R PP  P          
Sbjct: 109 QGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--------- 159

Query: 76  GVAGAGGRRCRACRARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREI 135
           G    GG + +         PG       QG    +    P  P+ P P+GD   + R  
Sbjct: 160 GPPPQGGNQPQG----PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD---KSRSS 212

Query: 136 RSPAAAPSRSSP-AQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSR 194
           +SP   P    P    +P G P  P +   G       +P     GP  PG   G  P  
Sbjct: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGNKPQ----GPPPPGKPQG--PPA 265

Query: 195 DGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLP 253
            G S++ S       P   P  P          P  P   +P  P+ P    PQ PP P
Sbjct: 266 QGGSKSQSARS----PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP 320



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 58/228 (25%), Positives = 78/228 (34%), Gaps = 37/228 (16%)

Query: 30  EGGRRGGGERPSSKPVRGAERALGSAQAQRHPPPLPTCALQRVDRLGVAGAGGRRCRACR 89
           +GG R  G  P  KP +G       +++ R PP  P          G    GG + +   
Sbjct: 124 QGGNRPQGPPPPGKP-QGPPPQGDKSRSPRSPPGKPQ---------GPPPQGGNQPQG-- 171

Query: 90  ARTSVLPGLRAVRRGQGQAAGRVCVAPDSPRLPVPRGDLKGRGREIRSPAAAPSRSSP-A 148
                 PG       QG    +    P  P+ P P+GD   + R  +SP   P    P  
Sbjct: 172 --PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD---KSRSSQSPPGKPQGPPPQG 226

Query: 149 QTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQL 208
             +P G P  P +   G       +P     GP  PG   G  P   G S++ S      
Sbjct: 227 GNQPQGPPPPPGK-PQGPPPQGGNKPQ----GPPPPGKPQG--PPAQGGSKSQSARS--- 276

Query: 209 YPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQ 256
                  PP  P        ++P    P PP     + PQ PP   PQ
Sbjct: 277 -------PPGKPQGPPQQEGNNPQ--GPPPPAGGNPQQPQAPPAGQPQ 315


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
            precursor [Homo sapiens]
          Length = 1194

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 42/154 (27%), Positives = 59/154 (38%), Gaps = 21/154 (13%)

Query: 192  PSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSP---SSPLFWSPLPPRLPTQRLPQ 248
            P R     +PS    +  P     PPL  H T   +P   + P     LPP  P Q+  Q
Sbjct: 965  PIRFSPPGSPSMVVHRRVPSAATTPPLPSHLTAEETPLFLAEPALPKGLPP--PLQQQQQ 1022

Query: 249  VPPLP---LPQIQALSSAWVVLPPG-----KGEEGPGPELHSGCLDGLRSLFEGPPCPYP 300
             PP     + Q+Q + S +    P       G  GPG        +GLRSL+  PP P  
Sbjct: 1023 PPPQQKSLMDQLQGVVSNFSTAIPDFHAVLAGPGGPG--------NGLRSLYPPPPPPQH 1074

Query: 301  GAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYE 334
               +P Q+        + P+ D    E   ++ E
Sbjct: 1075 LQMLPLQLSTFGEELVSPPADDDDDSERFKLLQE 1108


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 52/207 (25%), Positives = 69/207 (33%), Gaps = 56/207 (27%)

Query: 138 PAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGHAPSRDGA 197
           P  +P+++S       G+P Q          W    P           W +  APS    
Sbjct: 12  PEHSPAKTSAVSNTKPGQPPQ---------GWPGSNP-----------WNNPSAPSS--- 48

Query: 198 SRTPSGTEDQLYPGTLPFPP----LWPHSTTTTSPSSPLFWSPLPPRLPTQRLP------ 247
              PSG      P T+PF P    ++P    T  P  P   +P PP  P+   P      
Sbjct: 49  --VPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPGPP--APFPPSGPSCPPPGGPYPA 104

Query: 248 ------------QVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSG-CLDGLRSLFEG 294
                         P +P P++     A    P   G  GP   + SG    G+   +  
Sbjct: 105 PTVPGPGPTGPYPTPNMPFPELPRPYGA-PTDPAAAGPLGPWGSMSSGPWAPGMGGQYPT 163

Query: 295 PPCPYPG-----AWIPFQVPGTAHPSP 316
           P  PYP      A  P Q PG A P P
Sbjct: 164 PNMPYPSPGPYPAPPPPQAPGAAPPVP 190



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 37/136 (27%)

Query: 190 HAPSRDGA-SRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQ 248
           H+P++  A S T  G   Q +PG+ P+           +PS+P   S +P  LP    P 
Sbjct: 14  HSPAKTSAVSNTKPGQPPQGWPGSNPW----------NNPSAP---SSVPSGLP----PS 56

Query: 249 VPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQV 308
             P  +P   A +  +  +PP     GP P               GPP P+P +      
Sbjct: 57  ATPSTVPFGPAPTGMYPSVPP----TGPPP---------------GPPAPFPPSGPSCPP 97

Query: 309 PGTAHPSPATPSGDPS 324
           PG  +P+P  P   P+
Sbjct: 98  PGGPYPAPTVPGPGPT 113



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 56/229 (24%), Positives = 66/229 (28%), Gaps = 95/229 (41%)

Query: 116 PDSPRLPVPRGDLKGR---GREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEG 172
           P  P  P P G        G     P   P+   P   RP G P  PA            
Sbjct: 90  PSGPSCPPPGGPYPAPTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAA---------- 139

Query: 173 RPVCTRFGPLRPGW----QDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSP 228
                  GPL P W        AP   G   TP+          +P+P   P+       
Sbjct: 140 -------GPLGP-WGSMSSGPWAPGMGGQYPTPN----------MPYPSPGPY------- 174

Query: 229 SSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGL 288
                  P PP  P Q     PP+P          W  +PPG                  
Sbjct: 175 -------PAPP--PPQAPGAAPPVP----------WGTVPPGAW---------------- 199

Query: 289 RSLFEGPPCPYP---GAWI----------PFQVPGTAHPSPATPSGDPS 324
                GPP PYP   G++           PFQVP     +P  P G  S
Sbjct: 200 -----GPPAPYPAPTGSYPTPGLYPTPSNPFQVPSGPSGAPPMPGGPHS 243


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 40/138 (28%), Positives = 48/138 (34%), Gaps = 24/138 (17%)

Query: 116 PDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEGRPV 175
           P  P+ P P+GD   + R  RSP   P    P   +P G P Q      G    Q     
Sbjct: 74  PGKPQGPPPQGD---KSRSPRSPPGKPQGPPPQGGKPQGPPPQ------GGNKPQ----- 119

Query: 176 CTRFGPLRPGWQDGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWS 235
               GP  PG   G  P   G S++ S       P   P  P          P  P   +
Sbjct: 120 ----GPPPPGKPQG--PPAQGGSKSQSARS----PPGKPQGPPQQEGNNPQGPPPPAGGN 169

Query: 236 PLPPRLPTQRLPQVPPLP 253
           P  P+ P    PQ PP P
Sbjct: 170 PQQPQAPPAGQPQGPPRP 187


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 38/122 (31%), Positives = 45/122 (36%), Gaps = 26/122 (21%)

Query: 210 PGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPP 269
           PG LP PP+ P   T  +PS P    P PP+LP       PP P           VV PP
Sbjct: 256 PGGLPLPPMPP---TGPAPSGP----PGPPQLPPPAPGVHPPAP-----------VVHPP 297

Query: 270 GKGEEGPGPELHSGC------LDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDP 323
             G   P P +H           G+     G   P PG   P   PG   P+P      P
Sbjct: 298 ASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPP--APGVHPPAPGVHPPAP 355

Query: 324 SM 325
            +
Sbjct: 356 GV 357



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 37/124 (29%), Positives = 44/124 (35%), Gaps = 17/124 (13%)

Query: 214 PFPPLWPHSTTTTSPSSPLFWSPLPPRLP-TQRLPQVPP--LPLPQIQALSSA------- 263
           P PP  P          P   + LPPR P  + LP  PP  LPLP +     A       
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGP 277

Query: 264 WVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPS----PATP 319
             + PP  G   P P +H     G+     G   P PG   P   PG   P+    P  P
Sbjct: 278 PQLPPPAPGVHPPAPVVHPPA-SGVHPPAPGVHPPAPGVHPP--APGVHPPTSGVHPPAP 334

Query: 320 SGDP 323
              P
Sbjct: 335 GVHP 338



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 50/210 (23%), Positives = 62/210 (29%), Gaps = 28/210 (13%)

Query: 116 PDSPRLPVPRGDLKGRGREIRSPAAAPSRSSPAQTRPAGRPQQPARLALGERSWQEG-RP 174
           P  P+LP P   +      +  PA+     +P    PA     PA    G      G  P
Sbjct: 275 PGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAP---GVHPPTSGVHP 331

Query: 175 VCTRFGPLRPGWQ---DGHAPSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSP 231
                 P  PG      G  P   G      G       G  P  P    +     P +P
Sbjct: 332 PAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAP 391

Query: 232 LFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSL 291
               P P   P  + P V P P P +   +      PPG     PG              
Sbjct: 392 GVHPPAPGMHP--QAPGVHPQP-PGVHPSAPGVHPQPPGVHPSNPGVH------------ 436

Query: 292 FEGPPCPYPGAW---IPFQVPGTAHPSPAT 318
              PP P P      +P + PG   P P T
Sbjct: 437 ---PPTPMPPMLRPPLPSEGPGNIPPPPPT 463


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/219 (26%), Positives = 80/219 (36%), Gaps = 59/219 (26%)

Query: 133 REIRSPAAAPSRSSPAQTRPAG--RPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGH 190
           R++++PA +P+ S      P G  +PQ P R+ +  R             P RP  Q   
Sbjct: 716 RQLQAPAGSPAPSPS----PGGDDKPQVPPRVPIPPR-------------PTRPHVQLSP 758

Query: 191 APSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRL--------- 241
           AP   G   T         P   P  PL P  + T SP  P   SPLPPRL         
Sbjct: 759 APP--GEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMP 816

Query: 242 --------PTQRLPQVPPLPLPQI------------QALSSAWVVLPPGKGEEGPGPELH 281
                   P    PQV   P P+             +  S+ + +LP    E     E +
Sbjct: 817 TTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLP----ERPSYLERY 872

Query: 282 SGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPS 320
              L   +S  E  P P     +P  +P  + P+PA P+
Sbjct: 873 QRFLREAQSPEEPTPLP-----VPLLLPPPSTPAPAAPT 906



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 28/96 (29%)

Query: 237 LPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGE--EGPGPELHSGCLDGLRSLFEG 294
           +PPR+P      +PP P      LS A    PPG+ E  + PGP                
Sbjct: 739 VPPRVP------IPPRPTRPHVQLSPA----PPGEEETSQWPGPA--------------S 774

Query: 295 PPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLS 330
           PP   P    P    G+  PSP  P G   +   LS
Sbjct: 775 PPRVPPRE--PLSPQGSRTPSPLVPPGSSPLPPRLS 808


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
           sapiens]
          Length = 1086

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/219 (26%), Positives = 80/219 (36%), Gaps = 59/219 (26%)

Query: 133 REIRSPAAAPSRSSPAQTRPAG--RPQQPARLALGERSWQEGRPVCTRFGPLRPGWQDGH 190
           R++++PA +P+ S      P G  +PQ P R+ +  R             P RP  Q   
Sbjct: 794 RQLQAPAGSPAPSPS----PGGDDKPQVPPRVPIPPR-------------PTRPHVQLSP 836

Query: 191 APSRDGASRTPSGTEDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRL--------- 241
           AP   G   T         P   P  PL P  + T SP  P   SPLPPRL         
Sbjct: 837 APP--GEEETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPPRLSSSPGKTMP 894

Query: 242 --------PTQRLPQVPPLPLPQI------------QALSSAWVVLPPGKGEEGPGPELH 281
                   P    PQV   P P+             +  S+ + +LP    E     E +
Sbjct: 895 TTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLP----ERPSYLERY 950

Query: 282 SGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPS 320
              L   +S  E  P P     +P  +P  + P+PA P+
Sbjct: 951 QRFLREAQSPEEPTPLP-----VPLLLPPPSTPAPAAPT 984



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 29/96 (30%), Positives = 36/96 (37%), Gaps = 28/96 (29%)

Query: 237 LPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGE--EGPGPELHSGCLDGLRSLFEG 294
           +PPR+P      +PP P      LS A    PPG+ E  + PGP                
Sbjct: 817 VPPRVP------IPPRPTRPHVQLSPA----PPGEEETSQWPGPA--------------S 852

Query: 295 PPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLS 330
           PP   P    P    G+  PSP  P G   +   LS
Sbjct: 853 PPRVPPRE--PLSPQGSRTPSPLVPPGSSPLPPRLS 886


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,847,553
Number of Sequences: 37866
Number of extensions: 1779322
Number of successful extensions: 11171
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 848
Number of HSP's that attempted gapping in prelim test: 8935
Number of HSP's gapped (non-prelim): 2631
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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