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Search of human proteins with 237874289
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens]
(200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens] 410 e-115
gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens] 371 e-103
gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens] 72 3e-13
gi|239751182 PREDICTED: hypothetical protein [Homo sapiens] 72 3e-13
gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens] 72 3e-13
gi|22749023 transmembrane protein 56 [Homo sapiens] 34 0.073
gi|195972890 unc-84 homolog A isoform a [Homo sapiens] 33 0.16
gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens] 29 3.0
gi|109638743 hypothetical protein LOC83723 [Homo sapiens] 29 3.0
gi|6912464 latrophilin 2 precursor [Homo sapiens] 29 3.0
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ... 28 4.0
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [... 28 4.0
gi|61656212 olfactory receptor, family 8, subfamily U, member 9 ... 28 5.2
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 27 8.9
gi|4557257 adenylate cyclase 8 [Homo sapiens] 27 8.9
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 27 8.9
gi|52353304 olfactory receptor, family 8, subfamily U, member 1 ... 27 8.9
gi|61656205 olfactory receptor, family 8, subfamily U, member 8 ... 27 8.9
>gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens]
Length = 200
Score = 410 bits (1054), Expect = e-115
Identities = 200/200 (100%), Positives = 200/200 (100%)
Query: 1 MGYSAVPKCPPRGRGRDSVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQ 60
MGYSAVPKCPPRGRGRDSVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQ
Sbjct: 1 MGYSAVPKCPPRGRGRDSVWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQ 60
Query: 61 TRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLL 120
TRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLL
Sbjct: 61 TRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLL 120
Query: 121 YRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLR 180
YRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLR
Sbjct: 121 YRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLR 180
Query: 181 SDFCPEHVPKKQHKDKFLTE 200
SDFCPEHVPKKQHKDKFLTE
Sbjct: 181 SDFCPEHVPKKQHKDKFLTE 200
>gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens]
Length = 247
Score = 371 bits (952), Expect = e-103
Identities = 182/182 (100%), Positives = 182/182 (100%)
Query: 19 VWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAF 78
VWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAF
Sbjct: 66 VWQTPDMLVEIETAWSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAF 125
Query: 79 FSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLA 138
FSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLA
Sbjct: 126 FSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLA 185
Query: 139 PQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFL 198
PQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFL
Sbjct: 186 PQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMIIIYFSRLLRSDFCPEHVPKKQHKDKFL 245
Query: 199 TE 200
TE
Sbjct: 246 TE 247
>gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens]
Length = 264
Score = 72.0 bits (175), Expect = 3e-13
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 33 WSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGV 92
W+L +LV S GYF+ D D++ + +W+ L HH++ + + + +VG +
Sbjct: 77 WAL---VLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSM 133
Query: 93 LTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVN 152
++LL+E+++ L +R ++ +S L + V + +L LFRL P +++ + R +
Sbjct: 134 VSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHH 193
Query: 153 QRTLGTFLLG--ILLMLDVMIIIYFSRLLRSDFCPE--HVPKKQHK 194
Q L LG L+ + +M II R+L +D H P H+
Sbjct: 194 QVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHE 239
>gi|239751182 PREDICTED: hypothetical protein [Homo sapiens]
Length = 264
Score = 72.0 bits (175), Expect = 3e-13
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 33 WSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGV 92
W+L +LV S GYF+ D D++ + +W+ L HH++ + + + +VG +
Sbjct: 77 WAL---VLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSM 133
Query: 93 LTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVN 152
++LL+E+++ L +R ++ +S L + V + +L LFRL P +++ + R +
Sbjct: 134 VSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHH 193
Query: 153 QRTLGTFLLG--ILLMLDVMIIIYFSRLLRSDFCPE--HVPKKQHK 194
Q L LG L+ + +M II R+L +D H P H+
Sbjct: 194 QVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHE 239
>gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens]
Length = 264
Score = 72.0 bits (175), Expect = 3e-13
Identities = 45/166 (27%), Positives = 84/166 (50%), Gaps = 7/166 (4%)
Query: 33 WSLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGV 92
W+L +LV S GYF+ D D++ + +W+ L HH++ + + + +VG +
Sbjct: 77 WAL---VLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSM 133
Query: 93 LTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVN 152
++LL+E+++ L +R ++ +S L + V + +L LFRL P +++ + R +
Sbjct: 134 VSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHH 193
Query: 153 QRTLGTFLLG--ILLMLDVMIIIYFSRLLRSDFCPE--HVPKKQHK 194
Q L LG L+ + +M II R+L +D H P H+
Sbjct: 194 QVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHE 239
>gi|22749023 transmembrane protein 56 [Homo sapiens]
Length = 263
Score = 34.3 bits (77), Expect = 0.073
Identities = 29/132 (21%), Positives = 59/132 (44%), Gaps = 3/132 (2%)
Query: 41 VCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVS 100
+ ++GY I D I+ + +++HH ++ A++ + G LL E+S
Sbjct: 92 IAIASGYLISDLSIIILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELS 151
Query: 101 NIFLTIRMMMK-ISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTF 159
+ F+ R + + + +N + V++F+ R+A + L H+ Y T
Sbjct: 152 SPFVNQRWFFEALKYPKFSKAIVINGILMTVVFFIVRIA--SMLPHYGFMYSVYGTEPYI 209
Query: 160 LLGILLMLDVMI 171
LG+L+ L +I
Sbjct: 210 RLGVLIQLSWVI 221
>gi|195972890 unc-84 homolog A isoform a [Homo sapiens]
Length = 785
Score = 33.1 bits (74), Expect = 0.16
Identities = 18/60 (30%), Positives = 27/60 (45%)
Query: 53 VDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKI 112
+ V +R +W L V+A G SG+FW +G L+ N+FL R + I
Sbjct: 230 IGAVGQAVSRTAWSALWLAVVAPGKAASGVFWWLGIGWYQFVTLISWLNVFLLTRCLRNI 289
>gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]
Length = 202
Score = 28.9 bits (63), Expect = 3.0
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 13/63 (20%)
Query: 34 SLSGYLLVCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVL 93
SL G L+C +A ++ +G+T+ + E +H+ FFSGI VGGG+L
Sbjct: 13 SLVGLALLCIAANILLY-----FPNGETKYASE---NHLSRFVWFFSGI-----VGGGLL 59
Query: 94 TLL 96
LL
Sbjct: 60 MLL 62
>gi|109638743 hypothetical protein LOC83723 [Homo sapiens]
Length = 274
Score = 28.9 bits (63), Expect = 3.0
Identities = 31/130 (23%), Positives = 53/130 (40%), Gaps = 10/130 (7%)
Query: 56 VASGQTRASWEYLVHHV-MAMGAFFSGIFWSSFVGGGVL--TLLVEVSNIFLTIRMMMKI 112
+A G + ++HH M + F + W G L L+ EVS F+ + ++
Sbjct: 121 IARGYLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQ 180
Query: 113 SNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFL-------LGILL 165
Q LL++VN + L+ + R+ YL + R+ L L LG L
Sbjct: 181 YKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLPLLAVPLAIPAHVNLGAAL 240
Query: 166 MLDVMIIIYF 175
+L + +F
Sbjct: 241 LLAPQLYWFF 250
>gi|6912464 latrophilin 2 precursor [Homo sapiens]
Length = 1403
Score = 28.9 bits (63), Expect = 3.0
Identities = 34/140 (24%), Positives = 59/140 (42%), Gaps = 22/140 (15%)
Query: 25 MLVEI-ETAWSLSGYLLVCFSAGYFIHDTV-------DIVASGQTRASWEYLVHHVMAMG 76
MLVE+ E+ +S Y V AGY TV D + G +A W ++ ++ +
Sbjct: 925 MLVEVFESEYSRKKYYYV---AGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFI--- 978
Query: 77 AFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFR 136
WS F+G +L+ + + +T+ M+K SN R+ + V+
Sbjct: 979 -------WS-FIGPVTFIILLNIIFLVITLCKMVKHSNTLKPDSSRLENIKSWVLGAFAL 1030
Query: 137 LAPQAYLTHFFLRYVNQRTL 156
L F L ++N+ T+
Sbjct: 1031 LCLLGLTWSFGLLFINEETI 1050
>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
[Homo sapiens]
Length = 173
Score = 28.5 bits (62), Expect = 4.0
Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 36 SGYLLVCFSAGYFIHDTVDIVAS--GQTRASWEYLVHHVMAMGAFFSGIFW 84
S L V + + TV + G R SW Y++ V + FF+GIF+
Sbjct: 107 SSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFY 157
>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
[Homo sapiens]
Length = 215
Score = 28.5 bits (62), Expect = 4.0
Identities = 16/51 (31%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 36 SGYLLVCFSAGYFIHDTVDIVAS--GQTRASWEYLVHHVMAMGAFFSGIFW 84
S L V + + TV + G R SW Y++ V + FF+GIF+
Sbjct: 149 SSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFY 199
>gi|61656212 olfactory receptor, family 8, subfamily U, member 9
[Homo sapiens]
Length = 309
Score = 28.1 bits (61), Expect = 5.2
Identities = 17/59 (28%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Query: 102 IFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFL 160
+FL+I + + N LL R ++ +N MYF L+ A++ + + + LG FL
Sbjct: 30 LFLSIYLFTVVGNLGLILLIRTDEKLNTPMYFF--LSNLAFVDFCYSSVITPKMLGNFL 86
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 27.3 bits (59), Expect = 8.9
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 33 WSLSGYL--LVCFSAGYFIHDTVDIVASGQTRASWEY--LVHHVM 73
W+L G LV F YF+ + + ++GQ +W + LV VM
Sbjct: 968 WTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVM 1012
>gi|4557257 adenylate cyclase 8 [Homo sapiens]
Length = 1251
Score = 27.3 bits (59), Expect = 8.9
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 20/94 (21%)
Query: 87 FVGGGVLTLLVEVSNIFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHF 146
FV GVL ++ +FL + ++K++ V L+M ++ L +
Sbjct: 836 FVFTGVLAMVT--CAVFLRLNSVLKLA-------------VLLIMIAIYALLTETVYAGL 880
Query: 147 FLRYVN-----QRTLGTFLLGILLMLDVMIIIYF 175
FLRY N + LGT + +LLM ++ +++
Sbjct: 881 FLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFY 914
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 27.3 bits (59), Expect = 8.9
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 33 WSLSGYL--LVCFSAGYFIHDTVDIVASGQTRASWEY--LVHHVM 73
W+L G LV F YF+ + + ++GQ +W + LV VM
Sbjct: 968 WTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVM 1012
>gi|52353304 olfactory receptor, family 8, subfamily U, member 1
[Homo sapiens]
Length = 309
Score = 27.3 bits (59), Expect = 8.9
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 102 IFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFL 160
+FL+I + + N LL R + +N MYF L+ A++ + + + LG FL
Sbjct: 30 LFLSIYLFTVVGNLGLILLIRADTSLNTPMYFF--LSNLAFVDFCYSSVITPKMLGNFL 86
>gi|61656205 olfactory receptor, family 8, subfamily U, member 8
[Homo sapiens]
Length = 319
Score = 27.3 bits (59), Expect = 8.9
Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)
Query: 102 IFLTIRMMMKISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFL 160
+FL+I + + N LL R + +N MYF L+ A++ + + + LG FL
Sbjct: 30 LFLSIYLFTVVGNLGLILLIRADTSLNTPMYFF--LSNLAFVDFCYSSVITPKMLGNFL 86
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.143 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,185,285
Number of Sequences: 37866
Number of extensions: 263466
Number of successful extensions: 696
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 688
Number of HSP's gapped (non-prelim): 18
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.