Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 237858799
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237858799 adenylate kinase domain containing 1 isoform 1
[Homo sapiens]
(1911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 3830 0.0
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo... 849 0.0
gi|148746195 trichohyalin [Homo sapiens] 82 4e-15
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 73 3e-12
gi|110349719 titin isoform N2-A [Homo sapiens] 71 1e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 70 3e-11
gi|118498356 kinectin 1 isoform a [Homo sapiens] 69 3e-11
gi|33620775 kinectin 1 isoform a [Homo sapiens] 69 3e-11
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 68 7e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 68 1e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 68 1e-10
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 67 2e-10
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 67 2e-10
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 67 2e-10
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 67 2e-10
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 67 2e-10
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 67 2e-10
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 67 2e-10
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 67 2e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 66 3e-10
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 66 4e-10
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 66 4e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 65 5e-10
gi|148727333 adenylate kinase 7 [Homo sapiens] 64 1e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 1e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 2e-09
gi|118498368 kinectin 1 isoform c [Homo sapiens] 62 5e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 62 7e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 62 7e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 62 7e-09
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 3830 bits (9933), Expect = 0.0
Identities = 1911/1911 (100%), Positives = 1911/1911 (100%)
Query: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE
Sbjct: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
Query: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL
Sbjct: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
Query: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV
Sbjct: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
Query: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI
Sbjct: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
Query: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG
Sbjct: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
Query: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL
Sbjct: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
Query: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV 420
GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV
Sbjct: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV 420
Query: 421 DYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEK 480
DYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEK
Sbjct: 421 DYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEK 480
Query: 481 MEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKE 540
MEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKE
Sbjct: 481 MEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKE 540
Query: 541 TGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQP 600
TGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQP
Sbjct: 541 TGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQP 600
Query: 601 YEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYL 660
YEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYL
Sbjct: 601 YEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYL 660
Query: 661 SDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRR 720
SDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRR
Sbjct: 661 SDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRR 720
Query: 721 LLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE 780
LLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE
Sbjct: 721 LLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE 780
Query: 781 AVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFII 840
AVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFII
Sbjct: 781 AVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFII 840
Query: 841 LWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDY 900
LWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDY
Sbjct: 841 LWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDY 900
Query: 901 QTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREK 960
QTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREK
Sbjct: 901 QTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREK 960
Query: 961 IYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHI 1020
IYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHI
Sbjct: 961 IYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHI 1020
Query: 1021 QFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ 1080
QFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ
Sbjct: 1021 QFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ 1080
Query: 1081 LTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRG 1140
LTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRG
Sbjct: 1081 LTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRG 1140
Query: 1141 FFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE 1200
FFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE
Sbjct: 1141 FFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE 1200
Query: 1201 LILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAI 1260
LILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAI
Sbjct: 1201 LILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAI 1260
Query: 1261 ERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRA 1320
ERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRA
Sbjct: 1261 ERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKPLVENRA 1320
Query: 1321 SIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQY 1380
SIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQY
Sbjct: 1321 SIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYPVIHRQY 1380
Query: 1381 IYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHL 1440
IYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHL
Sbjct: 1381 IYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHL 1440
Query: 1441 SIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGY 1500
SIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGY
Sbjct: 1441 SIGGALRYVLNNHPETELALMLNWHLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGY 1500
Query: 1501 PVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNV 1560
PVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNV
Sbjct: 1501 PVTKHQMNLLEARSIIPMVIFELSVPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNV 1560
Query: 1561 KYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAA 1620
KYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAA
Sbjct: 1561 KYRKNIGEIRQYYQEQHQNWYVIDGFHSKWWVWNEVIKNVQMVNKYMQTYLERIKAGKAA 1620
Query: 1621 CIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEK 1680
CIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEK
Sbjct: 1621 CIDKLCITPQELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYKMSSQEK 1680
Query: 1681 LNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRY 1740
LNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRY
Sbjct: 1681 LNKFLENPELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRY 1740
Query: 1741 EALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPL 1800
EALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPL
Sbjct: 1741 EALVPGSINYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREPILLTSLPL 1800
Query: 1801 PGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKK 1860
PGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKK
Sbjct: 1801 PGYLEQGIATSLIKAMNAAGCLKPKFPFLSIRRSALLYIALHLKAFNPKGSEYTRKKYKK 1860
Query: 1861 KMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING 1911
KMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING
Sbjct: 1861 KMEQFMESCELITYLGAKMTRKYKEPQFRAIDFDHKLKTFLSLRNIDPING 1911
>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
sapiens]
Length = 421
Score = 849 bits (2194), Expect = 0.0
Identities = 419/421 (99%), Positives = 420/421 (99%)
Query: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE
Sbjct: 1 MTSQEKTEEYPFADIFDEDETERNFLLSKPVCFVVFGKPGVGKTTLARYITQAWKCIRVE 60
Query: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL
Sbjct: 61 ALPILEEQIAAETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
Query: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV
Sbjct: 121 SQDAMTTLQQIELIKNLNLKPDVIINIKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEV 180
Query: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI
Sbjct: 181 IENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENI 240
Query: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG
Sbjct: 241 VKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQG 300
Query: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL
Sbjct: 301 AEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPVNLKDGNIYSGLPDYSVSFL 360
Query: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVV 420
GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKV
Sbjct: 361 GKIYCLSSEEALKPFLLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVT 420
Query: 421 D 421
+
Sbjct: 421 N 421
Score = 67.8 bits (164), Expect = 1e-10
Identities = 98/404 (24%), Positives = 168/404 (41%), Gaps = 65/404 (16%)
Query: 1411 PIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGM 1470
P+ ++ G P GKTT+A+ IT + + L + ETE +ML L G
Sbjct: 30 PVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQI--AAETESGVMLQSMLISGQ 87
Query: 1471 TAPDELAIQ-ALELSLMESVCNTAGVVIDGYP-------VTKHQMNLLEARSIIPMVIFE 1522
+ PDEL I+ LE VC+ G +I P T Q+ L++ ++ P VI
Sbjct: 88 SIPDELVIKLMLEKLNSPEVCH-FGYIITEIPSLSQDAMTTLQQIELIKNLNLKPDVIIN 146
Query: 1523 LSVPSKEIFKRLLLEKE-NEQRLPYPLHNSAQIVAVNNVKYRKNI-----GEIRQYYQEQ 1576
+ P ++ +R+ +++ N Y V N+ K +K GE + +EQ
Sbjct: 147 IKCPDYDLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ 206
Query: 1577 HQNWYVIDGFHSKWWVWNEVIKN-VQMVNKYMQTYLERIKAGKAACIDKL-----CITPQ 1630
+ + F ++ + E++ + VQ Y++ +K K + L PQ
Sbjct: 207 EEE----EAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQ 262
Query: 1631 ELLSRLGEFEQFCPVSLAESQELFDCSATDSLEFAAEFRGHYYK--MSSQEKLNKFLENP 1688
L+ G ++ELF D L++ R ++E++N +EN
Sbjct: 263 YLIELNGN---------KPAEELF-MIVMDRLKYLNLKRAAILTKLQGAEEEINDTMEND 312
Query: 1689 ELYVPPLAPHPLPSADMIPKRLTLSELKSRFPKCAELQGYCPVTYKDGNQRYEALVPGSI 1748
EL+ L S +I R +S++ + CPV KDGN + G
Sbjct: 313 ELF------RTLASYKLIAPRYRWQ--RSKWGRT------CPVNLKDGN-----IYSGLP 353
Query: 1749 NYALEYHNRIYICENKEKLQKFLRSPLKYWEQKLPHKLPPLREP 1792
+Y++ + +IY ++E L+ FL +P P+ LPP+ P
Sbjct: 354 DYSVSFLGKIYCLSSEEALKPFLLNP-------RPYLLPPMPGP 390
Score = 64.3 bits (155), Expect = 1e-09
Identities = 84/381 (22%), Positives = 149/381 (39%), Gaps = 65/381 (17%)
Query: 1082 TEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEA-------Q 1134
TE +++S L+ + +P E++ ++ E + G+I+ P ++A +
Sbjct: 73 TESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIE 132
Query: 1135 FLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTI 1194
+ + PD + I+ D D+ R I + I
Sbjct: 133 LIKNLNLKPDVIINIKCPDYDLCQR----------------------ISGQRQHNNTGYI 170
Query: 1195 AKRRA--ELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKD--EEEMSGE 1250
R ++E +K+++ +D + EEE EE ++ I E + + +
Sbjct: 171 YSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRP 230
Query: 1251 EDEEQETDAIERLRGE-LGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLN 1309
ED + + I +L E + + E +++ + +YLI +NG + + +
Sbjct: 231 EDYLENVENIVKLYKETILQTLE------EVMAEHNPQYLI---ELNGNKPAEELFMIVM 281
Query: 1310 MKLKPLVENRASIFEKCHPIPAPLAQKM-------LTFTYKYI--------SSFGYWDPV 1354
+LK L RA+I K + M +YK I S +G PV
Sbjct: 282 DRLKYLNLKRAAILTKLQGAEEEINDTMENDELFRTLASYKLIAPRYRWQRSKWGRTCPV 341
Query: 1355 KLSEGETIKPVENAENPIYPVIHRQYIYFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRI 1414
L +G + P Y V IY LSS+E + F+ NP Y+ P P P P ++
Sbjct: 342 NLKDGNIYSGL-----PDYSVSFLGKIYCLSSEEALKPFLLNPRPYLLPPMPGP--PCKV 394
Query: 1415 IIVGPPKSGKTTVAKKITSEY 1435
I+GP SGKTT+ + Y
Sbjct: 395 FILGPQYSGKTTLCNMLAENY 415
Score = 56.2 bits (134), Expect = 3e-07
Identities = 65/245 (26%), Positives = 107/245 (43%), Gaps = 17/245 (6%)
Query: 778 EPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFP---EDSYPDVPEMEPFKEK 834
+PE + ++ + KG +E E E+ E + E E + V E + E
Sbjct: 177 DPEVIENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLEN 236
Query: 835 IGSFIILWKQ-----LEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ + + L+K+ LE ++E + L ++ +EL V++ ++ A LT
Sbjct: 237 VENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILT 296
Query: 890 G-EDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQP 948
+ EEE D E+ L + + + K G T CPV LK+ I
Sbjct: 297 KLQGAEEEINDTMENDELFRTLASYKLIAPRYRWQRSK--WGRT---CPVNLKDGNIYS- 350
Query: 949 GNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCG 1008
G + + + KIY SS EA + FL +P Y+ P+ PP ++ ++GPQ SGKT
Sbjct: 351 GLPDYSVSFLGKIYCLSSEEALKPFLLNPRPYLL--PPMPGPPCKVFILGPQYSGKTTLC 408
Query: 1009 RQLAE 1013
LAE
Sbjct: 409 NMLAE 413
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 82.4 bits (202), Expect = 4e-15
Identities = 140/626 (22%), Positives = 261/626 (41%), Gaps = 83/626 (13%)
Query: 677 QKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETD 736
+K+ E+ + + L EE +K++++E E + EEEL+ EEE E K + +E E
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 737 NEDEEEIEGDELEVHEEPEASHDTRGSWLPEEF-EASEVPETEPEAVSEPIEETTVETEI 795
E+EE + +E + EEPE R L ++ E E+ + E + + E E+ E E
Sbjct: 1141 REEEEVQQEEEQLLREEPE---KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 796 PKGSKEGLEIEKLSETVVLPEFPEDSYPDVP-EMEPFKEK-IGSFIILWKQLEATISEAY 853
+E L+ +K + ED D+ + EP KE + + K E +E +
Sbjct: 1198 QYREEEELQRQKRKQRY----RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE---NEQF 1250
Query: 854 IKILNLEIADRTPQELLQKVV---ETMEKPFQYTAWELTGEDYEEETE---DYQTEAE-V 906
++ + ++ DR Q+ LQ ++ + ++ + W+ + EE + + Q EA+
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 907 DEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEA-AKYREKIYYFS 965
D + +EE++ E++ ++R+R D K L + QP +E K+RE+
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE--ELR 1368
Query: 966 SAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEV 1025
E KFLE + E K + + C + + +F E
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKF---------LKEEQQLRCQEREQQLRQDRDRKFRE- 1418
Query: 1026 LQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEE 1085
+E+ L + E+ +F E E +Q +QE E ++ ++ +E +K E QL +E
Sbjct: 1419 -EEQQLSRQER--DRKFRE--EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Query: 1086 EVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDA 1145
E + E + + + E L+ R F E +FL +
Sbjct: 1474 EEQQLHRQERD------RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE------ 1521
Query: 1146 AVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILER 1205
+L Q ++ L+++++L R+ +R + +R
Sbjct: 1522 ------------QQLHRQQRQRKFLQEEQQLRRQ----------------ERGQQRRQDR 1553
Query: 1206 DKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQ--ETDAIERL 1263
D+K RE E ++ ++ D + E + + E+E EDE+Q + ++L
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 1264 RGELGEKFEADTHNLQIIQDELERYL 1289
R E KF D Q++Q+ E+ L
Sbjct: 1614 RQERDRKFREDE---QLLQEREEQQL 1636
Score = 75.1 bits (183), Expect = 6e-13
Identities = 133/646 (20%), Positives = 262/646 (40%), Gaps = 87/646 (13%)
Query: 677 QKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKE----- 731
Q K + + + ER L+ +++++E++E R E++LR E+E RR L + + +E
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERR---EQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 732 --AEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEA--SEVPETEPEAVSEPI- 786
+E+ ++EE L+ EE + R L E E ++ + E E + +
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 787 --EETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQ 844
+E +E + + E LE E+ E + E PE+
Sbjct: 592 REQEERLEQRLKREEVERLEQEERREQRLKREEPEE------------------------ 627
Query: 845 LEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEA 904
E ++L E + Q+ L++ E E+ Q E E E+ + E
Sbjct: 628 ------ERRQQLLKSEEQEERRQQQLRR--EQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 905 EVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYF 964
++EL EEE+E+ +++K R + +P E + +E+
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE--- 736
Query: 965 SSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEE 1024
+E L+ E+ AH + + R Q K+ GRQ Q E
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796
Query: 1025 VLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEE 1084
L+ + + E++ PE EE + + ++ +EL EEE +++ QL EE
Sbjct: 797 QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE----EEEQLQRRERAQQLQEE 852
Query: 1085 EEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPD 1144
E+ ++ + E W L+E + L P E Q ++ +
Sbjct: 853 EDGLQED--QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE--QLRKEQQLLQE 908
Query: 1145 AAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAK---------IRVDTIA 1195
+Q ++++ R Q +++ +++ + E ++L+++ + K R D
Sbjct: 909 EEEELQREERE--KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 1196 KRRAELIL-----ERDKKRRENVVRDDEEISEEE---LEEDND-------DIENILEDEF 1240
+++ E +L +R ++ RE R++EE+ +EE L E+ + + + +DE
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 1241 PKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELE 1286
++EE++ EE E++ ER + E+ E Q++ +E E
Sbjct: 1027 QQEEEQLLREEREKRRLQERER---QYREEEELQQEEEQLLGEERE 1069
Score = 73.6 bits (179), Expect = 2e-12
Identities = 139/661 (21%), Positives = 272/661 (41%), Gaps = 102/661 (15%)
Query: 655 DLVIYLSDTENNGKCLFNRIYL---------------------QKKSEIDSKILERLLEE 693
DL++ L D ++NG+ FN L +K++ D K E
Sbjct: 55 DLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRARCDGK------ES 108
Query: 694 LQKKKKEEEEARKATEEELRLEEE-NRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHE 752
L + +++EE+ R+ + +LEEE +R + + + +E E + + E++ ++ +
Sbjct: 109 LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQR 168
Query: 753 EPEASHDTRGSWLPEEFEASEVPETEP----EAVSEPIEETTVETEIPKGSKEGLEIEKL 808
E R W E +E + + E P EE E+ + ++G E EK
Sbjct: 169 RDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE-EKQ 227
Query: 809 SETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQE 868
+ + V + E KE W++ E + + K L+ + Q
Sbjct: 228 QQR-------RERQDRVFQEEEEKE--------WRKRETVLRKEEEK---LQEEEPQRQR 269
Query: 869 LLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRH 928
LQ+ E + K EL E EEE + + E ++L ++EEE ++ +ER+
Sbjct: 270 ELQEEEEQLRK---LERQELRRERQEEEQQQQRLRRE--QQLRRKQEEERREQQEERREQ 324
Query: 929 LGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLK 988
+ +E Q E+ + +++ E +E+ L ++ E+ L+
Sbjct: 325 QERREQ------QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 989 APPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSEN 1048
L Q + R+ + ++ E+ L+ + L+ E+++ E +E+ +
Sbjct: 379 REQQ---LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE-QEEERH 434
Query: 1049 EQAAKQELEELAIQANVKVEEENTKKQLPEVQLTE--EEEVIKSSLMENEPLPPEILEVI 1106
EQ +QE E +K E+E + L + TE E+E K L ++ E
Sbjct: 435 EQKHEQERRE----QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ-------EEE 483
Query: 1107 LSEWWLK---EPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA 1163
E WLK E R + E Q ++ + + Q +++ + RL
Sbjct: 484 RRERWLKLEEEERRE--------QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Query: 1164 Q----IEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEE 1219
Q ++ + +Q K E +K ++ + + R+ + R + +L+R+++RR+ ++ ++E
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 1220 ------ISEEELE--EDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKF 1271
+ EE+E E + E L+ E P++E + EEQE ++LR E E+
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 1272 E 1272
E
Sbjct: 656 E 656
Score = 69.7 bits (169), Expect = 3e-11
Identities = 136/666 (20%), Positives = 269/666 (40%), Gaps = 81/666 (12%)
Query: 678 KKSEIDSKILERLLEELQKKKKEEEEARKAT--EEELRLEEENR----------RLLELM 725
K+ E + ++ +RL E Q ++++EE + EEE RLE+E R R +L+
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 726 KVKAKEAEETDNEDEEE-----IEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE 780
K + + ++ ++EE ++ +E+E E+ E PEE ++ ++E +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 781 AVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPD---VPEMEPFKEKIGS 837
+ + E + + E E+ E + E E+ E E +E+I S
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Query: 838 FIILWK-QLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEE 896
I W+ QLE+ K+ + + Q Q+ E + W+ + ++
Sbjct: 700 RIPKWQWQLESEADARQSKVYS-RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
Query: 897 TEDYQTEAEVDEELEEEEEEEGEDKM-------KERKRHLGDTKHFCPVVLKENFILQPG 949
E+ Q + EE+ E G ++ ++R+R L + ++ F+ +
Sbjct: 759 QEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER---QQREQRFLPEEE 815
Query: 950 NTEEAAKY---REKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTM 1006
E+ + REK F E + + E + E+ L+ R + K
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 1007 CGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVK 1066
+ K + + LQE+ L+ E+++ E EE+ + E+ K+ +E Q
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQ--LRKEQQLLQEEEEELQREEREKRRRQEQERQ---- 929
Query: 1067 VEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGF 1126
EE +Q E L EE E + E + + L+ + +EP + +
Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989
Query: 1127 PRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLE--------- 1177
R EE Q Q ++Q + + + ++W+ + +KK E
Sbjct: 990 YREEEELQ---------------QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 1178 ----RKKLIKDMKAKIRVDTIAKRRAELIL--ERDKKRR---ENVVRDDEEISEEE---L 1225
K+ +++ + + R + ++ E +L ER+ +RR E R +EE+ +EE L
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 1226 EEDNDDIENILEDEFPKDEEEMSGEED----EEQETDAIERLRGELGEKFEADTHNLQII 1281
E+ + + ++EEE+ EE+ EE+E + L + E+ E Q++
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 1282 QDELER 1287
++E E+
Sbjct: 1155 REEPEK 1160
Score = 67.8 bits (164), Expect = 1e-10
Identities = 123/617 (19%), Positives = 258/617 (41%), Gaps = 90/617 (14%)
Query: 670 LFNRIYLQKKSEIDSKILERLLEELQ-----KKKKEEEEARKATEEELRLEEENRRLLEL 724
L+ + LQ++ + ++L+ EELQ K++++E+E + EE+L+ EEE E
Sbjct: 889 LYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREER 948
Query: 725 MKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSE 784
K + +E E +D++ + +E + EEPE R +++ E + E E +
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGEEPE---KRRRQEREKKYREEEELQQEEEQLLR 1005
Query: 785 PIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQ 844
E E + ++ E+++ E ++ E E +E+ + +
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREE---------REKRRLQERERQY-----R 1051
Query: 845 LEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEE-ETEDYQTE 903
E + + ++L E R QEL ++ E+ Q +L E+ E+ ++ + +
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQY--RKEEELQQEEEQLLREEPEKRRRQERERQ 1109
Query: 904 AEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYY 963
+EEL++EEE+ ++ ++R+R E +YRE
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQ-----------------------ELERQYRE---- 1142
Query: 964 FSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFE 1023
E+ ++ E+ + EEP K + RQ E+ + + E
Sbjct: 1143 -------EEEVQQEEEQLLREEPEK-------------RRRQELERQYREEEEL-QQEEE 1181
Query: 1024 EVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTE 1083
++L+E+ + +++ EE+ Q KQ + ++++K + E PE +
Sbjct: 1182 QLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE------PEKENAV 1235
Query: 1084 EEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFP 1143
+ + ENE ++ + L + ++ ++ R E ++ FP
Sbjct: 1236 RDNKVYCKGRENEQF-RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFP 1294
Query: 1144 DAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELI- 1202
+ + + ++ R +Q EK L+++++ +R++ D K + + +R + +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 1203 -LERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIE 1261
ERD+K RE +R E+ + LEE+ E +F K+E+++ +E E+Q
Sbjct: 1355 RQERDRKFREEELRHQEQ-GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ------ 1407
Query: 1262 RLRGELGEKFEADTHNL 1278
LR + KF + L
Sbjct: 1408 -LRQDRDRKFREEEQQL 1423
Score = 53.1 bits (126), Expect = 2e-06
Identities = 133/642 (20%), Positives = 258/642 (40%), Gaps = 94/642 (14%)
Query: 677 QKKSEIDSKILE--RLLEELQKKK-KEEEEARKATEEELRLEEENRRLLEL-MKVKAKEA 732
+++ E D K E +LL+E +++ + +E RK EEELR +E+ R+ LE +++ +E
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER 1388
Query: 733 EETDNEDEEEIEGDELEVH-----------EEPEASHDTRGSWLPEEFEASEVPETEPEA 781
E ++E+++ E E EE + S R EE + E E +
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 782 VSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIIL 841
+ E E+ + K +E +++ E + + + + + + +E+ F
Sbjct: 1449 LEE--EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKF--- 1503
Query: 842 WKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQ 901
++ E E K L E Q + + E + Q + + + E+ Q
Sbjct: 1504 -REQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562
Query: 902 TEAEVDEELEEEEEEEGEDKMKERK-RHLGDTKHFCP--VVLKENFILQPGNTEEAAKYR 958
E +E+ +E + + +++E+K R + F L+ Q E K+R
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFR 1622
Query: 959 EKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIF 1018
E E ++ + + EEP R +QL +
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQER--------------EQQLRHDRDRK 1668
Query: 1019 HIQFEEVLQE---KLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQ 1075
+ E++LQE + L + E+ +F E E +Q +QE E +Q EE+ ++Q
Sbjct: 1669 FREEEQLLQEGEEQQLRRQERD--RKFRE--EEQQLRRQERERKFLQ-----EEQQLRRQ 1719
Query: 1076 LPEVQLTEEEEVIKSS-------------LMENEPLPPEILEVILSEWWLKEPIRSTGFI 1122
E + EEE++ + + ++E E L PE E L+ R F
Sbjct: 1720 ELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE-----REEQQLRRQERDRKFR 1774
Query: 1123 LDGFPRYPEEAQFL----GDRGFFPDAAVFIQVDDQDIFDRLLPAQIE---KWKLKQKKK 1175
+ R E Q L DR F + + + ++Q +L P Q + +W+
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ----QLRPQQRDGKYRWE------ 1824
Query: 1176 LERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENI 1235
E + +++ + ++R + + RAE +K R R+++E+ +EE ++ + E
Sbjct: 1825 -EEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR----REEQELWQEEEQKRRQERERK 1879
Query: 1236 LEDEFPKDEEEMSGEEDEEQETDAIERLRGE-LGEKFEADTH 1276
L +E + +++ EE ++ I+ G+ G E TH
Sbjct: 1880 LREEHIRRQQK---EEQRHRQVGEIKSQEGKGHGRLLEPGTH 1918
Score = 52.4 bits (124), Expect = 4e-06
Identities = 123/653 (18%), Positives = 267/653 (40%), Gaps = 78/653 (11%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEE-----ELRLEEENRRLLELMKVKAK 730
L+++ + + + +RL E Q ++K+EEE R+ EE E R ++E RR +L + + +
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345
Query: 731 EAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETT 790
E+ ++EE E E ++ E E + R L E + + E ++
Sbjct: 346 RREQQLRREQEE-ERREQQLRREQE--EERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 791 VETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATIS 850
E ++ + + E + E + E E+ + E E +++ L+
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR----------LKREQE 452
Query: 851 EAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEEL 910
E + E +R QE ++ ++ ++ + W E+ E ++ + +++L
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR-----EQQL 507
Query: 911 EEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAK 970
E+EE E ++K ++ L++ + E + RE++ E K
Sbjct: 508 RREQEERREQRLKRQEEE---------ERLQQRLRSEQQLRREQEERREQL--LKREEEK 556
Query: 971 EKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKL 1030
E E + E+ + L L + + R+ E+L ++ EEV + +
Sbjct: 557 RLEQERREQRLKREQEERRDQL---LKREEERRQQRLKREQEERLE-QRLKREEVERLEQ 612
Query: 1031 LLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKS 1090
+ E+++ E E+ +Q K E +E Q ++ E++ ++Q ++ EEEE ++
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ--RLKREEEEERLEQ 670
Query: 1091 SLM---ENEPLPPEILE-------------VILSEWWLKEPIRSTGFILDGFPRYPE--- 1131
L E E E+ E + +W L+ + + PR E
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 1132 EAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIE----KWKLKQKKKLERKKLI----- 1182
Q ++ ++ + Q +++ + Q +W+ ++K + R++L
Sbjct: 731 RRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL 790
Query: 1183 -KDMKAKIRVDTIAKRRAELILERDKK---RRENVVRDDE-EISEEELEEDNDDIENILE 1237
+ + ++R + +R + E ++K RR+ R+ E + EEE + + L+
Sbjct: 791 REQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 1238 DEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNL---QIIQDELER 1287
+E +E+ +EQ D ++ R +L E+ + H L +Q++L +
Sbjct: 851 EEEDGLQEDQERRRSQEQRRD--QKWRWQLEEERKRRRHTLYAKPALQEQLRK 901
Score = 35.4 bits (80), Expect = 0.54
Identities = 54/266 (20%), Positives = 103/266 (38%), Gaps = 5/266 (1%)
Query: 673 RIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRL---EEENRRLLELMKVKA 729
R +LQ++ ++ + + + + +K EEE + EE +L E + + LE KV+
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 730 KEAEETDNEDEEEIEGDELEVHEEPEASHDTR-GSWLPEEFEASEVPETEPEAVSEPIEE 788
+E E EDE+++ E + E R L +E E ++ E + E
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 789 TTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEAT 848
E + + + + E +L E E F+E+ ++ +
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 849 ISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQ-TEAEVD 907
E ++ LE R ++L Q+ + + + L E E E+ Q E D
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 908 EELEEEEEEEGEDKMKERKRHLGDTK 933
+ EEE+ E + ++ + D K
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRK 1796
Score = 33.1 bits (74), Expect = 2.7
Identities = 26/114 (22%), Positives = 56/114 (49%), Gaps = 7/114 (6%)
Query: 1169 KLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKK---RRENVVRDDEEISEEEL 1225
+L++++ LE ++ ++ K + R +R+ + E ++K +RE V+R +EE +EE
Sbjct: 209 QLRRRELLELRRKGREEKQQQR----RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Query: 1226 EEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQ 1279
+ +++ E + +E+ E EE++ R +L K E + Q
Sbjct: 265 PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Score = 31.6 bits (70), Expect = 7.8
Identities = 52/263 (19%), Positives = 106/263 (40%), Gaps = 41/263 (15%)
Query: 1043 EEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI 1102
EED + ++LEE Q + +E ++ + +E++E ++ + E
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD---EE 172
Query: 1103 LEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGF----FPDAAVFIQVDDQDIFD 1158
L EW +E R+ EE Q +G FPD ++Q
Sbjct: 173 LWRQRQEWQEREERRA------------EEEQLQSCKGHETEEFPD-------EEQLRRR 213
Query: 1159 RLLPAQIEKWKLKQKKKLERKKLI---KDMKAKIRVDTIAKRRAELILERDKKRRENVVR 1215
LL + + + KQ+++ ER+ + ++ K + +T+ ++ E + E + +R+ +
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 1216 DDEEI------------SEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERL 1263
++E++ EEE ++ E L + ++ E E E+QE +
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 1264 RGELGEKFEADTHNLQIIQDELE 1286
R E + E + Q ++ E E
Sbjct: 334 RREQQLRREQEERREQQLRREQE 356
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 72.8 bits (177), Expect = 3e-12
Identities = 129/634 (20%), Positives = 276/634 (43%), Gaps = 77/634 (12%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEET 735
++K+ E + ERL E+ K +++EE K +E RL E+ + L E K + +E +E
Sbjct: 288 IRKQEEKMWRQEERLREQEGKMREQEE---KMWRQEKRLREQEKELREQEK-ELREQKEL 343
Query: 736 DNEDEEEIEGDELEVHEEPEASHDTRGSWLPEE--FEASEVPETEPEAVSEPIEETTVET 793
++E+ E +E +E + W EE +E + + + + + E +
Sbjct: 344 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD 403
Query: 794 EIPKGSKEGL-EIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEA 852
E + +E + E EK+ E V + + +EK+ Q E I E
Sbjct: 404 ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM--------QEEERIRER 455
Query: 853 YIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEE 912
K+ E R +E +QK E M WE ++++++ Q E ++E +
Sbjct: 456 EKKMREEEETMREQEEKMQKQEENM--------WEQEEKEWQQQRLPEQKEKLWEQEKMQ 507
Query: 913 EEEE---EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEA 969
E+EE E E+K+++++ G K Q EE + +E+ +
Sbjct: 508 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 567
Query: 970 KEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEK 1029
++K E + EE ++ R+ + + R+ EK+ + +E QE+
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEE-RMREREKKMREEEEMMREQEEKMQEQEEKMQE--QEE 624
Query: 1030 LLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE----ENTKKQLPEVQLTEEE 1085
+ + E+K+ + E+ E E+ ++ E++ Q + ++ E+ K Q E +EE
Sbjct: 625 KMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Query: 1086 EVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDR-GFFPD 1144
++ + ME + E + W +E +R + + + EE + + ++ +
Sbjct: 685 KIWEQEKMEKKTQEQE------KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE 738
Query: 1145 AAVFIQVDDQDIFD---------------RLLPAQIEK-W---KLKQKKKL-ERKKLIKD 1184
+Q ++++++ + LP Q EK W K+++++K+ E+++ ++D
Sbjct: 739 QEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRD 798
Query: 1185 MKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEI---------SEEELEEDNDDIENI 1235
+ K+R R E E+ + + E + +E++ EE++ + +E
Sbjct: 799 QEEKMRGQEEKMRGQE---EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Query: 1236 L---EDEFPKDEEEMSGEEDEEQETDAIERLRGE 1266
+ E++ + EE+M G+E++ +E + E++RG+
Sbjct: 856 MQGQEEKMREQEEKMRGQEEKMREQE--EKMRGQ 887
Score = 70.5 bits (171), Expect = 2e-11
Identities = 124/591 (20%), Positives = 244/591 (41%), Gaps = 119/591 (20%)
Query: 688 ERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDE 747
E L E + K +E+EE K +E RL E+ + L E K + +E +E ++E+ E +E
Sbjct: 299 EERLREQEGKMREQEE--KMWRQEKRLREQEKELREQEK-ELREQKELREQEEQMQEQEE 355
Query: 748 LEVHEEPEASHDTRGSWLPEE--FEASEVPETEPEAVSEPIEETTVETEIPKGSKEGL-E 804
+E + W EE +E + + + + + E + E + +E + E
Sbjct: 356 KMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 415
Query: 805 IEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADR 864
EK+ E V + + +EK+ Q E I E K+ E R
Sbjct: 416 QEKMWEQVEKMREEKKMQEQEKKTRDQEEKM--------QEEERIREREKKMREEEETMR 467
Query: 865 TPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE---EGEDK 921
+E +QK E M WE ++++++ Q E ++E +E+EE E E+K
Sbjct: 468 EQEEKMQKQEENM--------WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 922 MKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYV 981
+++++ G K E+ + ++++ E +EK + +
Sbjct: 520 IRDQEEMWGQEKKMW-------------RQEKMREQEDQMW-----EQEEKMRDQEQKMW 561
Query: 982 AHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPE 1041
EE ++ ++ E+ Q E++ +E+ + + EKK+ E
Sbjct: 562 DQEERME--------------------KKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 1042 FEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPE 1101
EE ++ QE EE + K+ E+ K Q E ++ E+EE + E E
Sbjct: 602 -EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE----KMWEQE----- 651
Query: 1102 ILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLL 1161
+ W ++ R PE+ + L + ++ +Q+
Sbjct: 652 ------EKMWEQQ-------------RLPEQKEKLWEHE---------KMQEQE------ 677
Query: 1162 PAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEI- 1220
Q ++ K+ +++K+E+K ++ K D R E + ER+KK +R++EE+
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTW---DQEKMREEESMREREKK-----MREEEEMM 729
Query: 1221 --SEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGE 1269
EE+++E + ++ E+E + EE+M +E++ E + + +L E
Sbjct: 730 REQEEKMQEQEEKMQE-QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Score = 54.7 bits (130), Expect = 9e-07
Identities = 126/603 (20%), Positives = 248/603 (41%), Gaps = 89/603 (14%)
Query: 692 EELQKKKKEEEEARKATEEE-----LRLEEENRRLLE----LMKVKAKEAEETDNEDEEE 742
EEL+KK E +E E E L ++E R+L L +V+ +E EEE
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 743 IEGDELEVHEEPEASHDTRGSWLPEEF---EASEVPETEPEAVSEPIEETTVETEIPKGS 799
+ E ++ ++ E W EE + ++ E E + + E E+ +
Sbjct: 281 LREQEKKIRKQEEKM------WRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334
Query: 800 KEGLEIEKLSETVV-LPEFPEDSYPDVPEMEPFKEKIG-SFIILWKQLEATISEAYIKIL 857
KE E ++L E + E E + +M +EK+ LW+Q E + E K+
Sbjct: 335 KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMREQEQKMR 393
Query: 858 NLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE- 916
+ E E L++ E M + Q WE + EE+ Q + D+E + +EEE
Sbjct: 394 DQEERMWEQDERLREKEERMRE--QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 917 --EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNT---EEAAKYREKIYYFSSAEAKE 971
E E KM+E + + + + +EN Q + + +EK++ + +E
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQE 510
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ + E+ + +E + G K M + EK+ Q E QE+ +
Sbjct: 511 EKIWEQEEKIRDQEEM------------WGQEKKMWRQ---EKMREQEDQMWE--QEEKM 553
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
E+K+ + E + QE E+ K+ EE ++ E ++ EEEE+++
Sbjct: 554 RDQEQKMW----DQEERMEKKTQEQEKKTWDQEEKMREEERMRER-EKKMREEEEMMREQ 608
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
+ + ++ E W +E ++ EE + + + +
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQ-----------EEKMWEQEEKMW-------EQ 650
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
+++ + LP Q EK L + +K++ ++ +++ + KI E++K ++
Sbjct: 651 EEKMWEQQRLPEQKEK--LWEHEKMQEQEKMQEQEEKI-------------WEQEKMEKK 695
Query: 1212 NVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKF 1271
++ + +E++ E+ E++ E E EEE E EE+ + E+++ + E +
Sbjct: 696 TQEQEKKTWDQEKMREE----ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 1272 EAD 1274
E +
Sbjct: 752 EQE 754
Score = 52.0 bits (123), Expect = 6e-06
Identities = 123/622 (19%), Positives = 247/622 (39%), Gaps = 95/622 (15%)
Query: 693 ELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHE 752
+L+++KK + ++A E+ ++ R+L K + + A + + E L
Sbjct: 78 QLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGTPS 137
Query: 753 E----------------------PEASHDTRG----SW--LPEEFEASEVPETEPEAVSE 784
P S D G SW E A T +
Sbjct: 138 SFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADR 197
Query: 785 PIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIIL-WK 843
IEE T E ++ L +E T+ E + + ++ E P E S I L K
Sbjct: 198 YIEELTKE-------RDALSLELYRNTITNEELKKKN-AELQEKLPLAESEKSEIQLNVK 249
Query: 844 QLEATISEAYIKILNLEIADRTPQELLQKVVETM---EKPFQYTAWEL-TGEDYEEETED 899
+L+ + A K L ++ T QE + + E + EK + ++ E+ E E
Sbjct: 250 ELKRKLERA--KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG 307
Query: 900 YQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYRE 959
E E +E+ E E +++E+++ L + K L+E E+ + E
Sbjct: 308 KMREQEEKMWRQEKRLREQEKELREQEKELREQKE-----LREQ-------EEQMQEQEE 355
Query: 960 KIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFH 1019
K++ E +EK E E EE L Q +++ ++
Sbjct: 356 KMW-----EQEEKMREQEEKMWRQEERL----------WEQEKQMREQEQKMRDQEERMW 400
Query: 1020 IQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEV 1079
Q E + +++ ++ ++K+ + E+ E ++ +QE ++ Q EEE +++ E
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE-KKTRDQEEKMQEEERIRER--EK 457
Query: 1080 QLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDR 1139
++ EEEE ++ + + + E EW + R PE+ + L ++
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ--------------RLPEQKEKLWEQ 503
Query: 1140 GFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIA---- 1195
+ I ++ I D+ EK +Q+K E++ + + + K+R
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 1196 -KRRAELILERDKKR--RENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEED 1252
+R + E++KK +E +R++E + E E ++ ++ E + E E E+E +E
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMRERE-KKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 1253 EEQETDAIERLRGELGEKFEAD 1274
EE+ + E+++ + + +E +
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQE 644
Score = 47.8 bits (112), Expect = 1e-04
Identities = 88/405 (21%), Positives = 155/405 (38%), Gaps = 71/405 (17%)
Query: 895 EETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEA 954
EE + E + L E E+ E + +KE KR L K P V + EE
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 280
Query: 955 AKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEK 1014
+ +EK K + E EE L+ + GK R+ EK
Sbjct: 281 LREQEK-----------KIRKQEEKMWRQEERLR-----------EQEGKM---REQEEK 315
Query: 1015 LNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKK 1074
+ + E QEK L + EK++ + E + EQ QE EE + K+ E+ K
Sbjct: 316 MWRQEKRLRE--QEKELREQEKELREQKELREQEEQM--QEQEEKMWEQEEKMREQEEKM 371
Query: 1075 QLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQ 1134
E +L E+E+ ++ + + E +E +R + + + EE +
Sbjct: 372 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKK 431
Query: 1135 FLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTI 1194
+ EK Q++K++ ++ I++ + K+R +
Sbjct: 432 M---------------------------QEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 1195 AKRRAELILERDKKRRENVVRDDE-EISEEELEEDNDDI----------ENILEDEFP-K 1242
R E E+ +K+ EN+ +E E ++ L E + + E I E E +
Sbjct: 465 TMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 521
Query: 1243 DEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
D+EEM G+E + + + ++ E+ E Q + D+ ER
Sbjct: 522 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Score = 42.7 bits (99), Expect = 0.003
Identities = 87/488 (17%), Positives = 202/488 (41%), Gaps = 64/488 (13%)
Query: 451 KVVKEKLLRELQAR-KQAETALREFQRQYEKMEFGVFPMEATH------SSIDEEGYIQG 503
K+ +E+ +RE + + ++ E +RE + + +K E ++ E E+ + Q
Sbjct: 445 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 504
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
+++ + + EE K + + + Q K+ + + E +++ + Q+ K++
Sbjct: 505 KMQEQEEKIWEQEE-KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 564 TAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRF 623
E+ +E+ T + + EE ++ + + + + E + E M+E +++
Sbjct: 564 ----EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 624 PGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEID 683
+ ++W K + + E +++ Q++ +
Sbjct: 620 QEQEE-------------KMWEQEEK----------MQEQEEKMWEQEEKMWEQEEKMWE 656
Query: 684 SKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEI 743
+ L E+L + +K +E+ K E+E ++ E+ + + + + K ++ +EE +
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQ-EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 744 EGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGL 803
E ++ EE E E E + + E + E EE + E K
Sbjct: 716 REREKKMREEEEMMR-----------EQEEKMQEQEEKMQEQEEEMWEQEE-----KMWE 759
Query: 804 EIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIAD 863
+ EK+ E LPE E + E +EKI W+Q E + + K+ E
Sbjct: 760 QEEKMWEQQRLPEQKEKLWEHEKMQE--QEKI------WEQ-EEKMRDQEEKMRGQEEKM 810
Query: 864 RTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE--EGEDK 921
R +E ++ E M + W + + +E + + E +++E+++ +EE+ E E+K
Sbjct: 811 RGQEEKMRGQEEKMWGQ-EEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEK 869
Query: 922 MKERKRHL 929
M+ ++ +
Sbjct: 870 MRGQEEKM 877
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 70.9 bits (172), Expect = 1e-11
Identities = 150/636 (23%), Positives = 257/636 (40%), Gaps = 114/636 (17%)
Query: 677 QKKSEIDSKILERLLEELQKKKKEEEEARKATE--EELRLEEENRRLLELMKVKAKEAEE 734
+++ E +K+ E ++++K E ++ + +E+ + EE R L + E
Sbjct: 9683 KREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQRE 9742
Query: 735 TDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPE---TEPEAVS--EPIEET 789
+ E+ EE + E E +E P +D + E+E E E TEPE +P+ E
Sbjct: 9743 EEYEEYEEYDYKEFEEYE-PTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEE 9801
Query: 790 TVETEIPKGS-----KEGLEIEKLSETVVLPEFPEDSYPDVPEMEP---FKEKIGSFIIL 841
V T+ PK K+ + EK+ V +P+ + P VPE EP F+EKI I
Sbjct: 9802 PVPTK-PKAPPAKVLKKAVPEEKVP--VPIPKKLKPPPPKVPE-EPKKVFEEKIRISITK 9857
Query: 842 WKQLEAT-------------ISEAYIKILNLEIAD-----RTPQELLQKVVETMEKPFQY 883
++ + T ++E + + E+A P+EL + V E+ +
Sbjct: 9858 REKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTH 9917
Query: 884 TAWELTGED--YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLK 941
L E+ Y E E++ TE EV + + E + E K+ PV +
Sbjct: 9918 VEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKK---------PVPVP 9968
Query: 942 ENFILQPGNTEEAAKY-REKIYYFSSAEAKE---KFLEHPEDYVAHEE-------PLKAP 990
+ P E K EK+ + K K E P+ V E+ ++AP
Sbjct: 9969 KKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAP 10028
Query: 991 PLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQ 1050
P ++ V + + +K+ + EV K L+ EKK P ++
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEV--PKKLIPEEKKPTPVPKKVEAPPP 10086
Query: 1051 AAKQELEELAIQANVKVEEE--------NTKKQLPEVQ--LTEEEEVIKSS---LMENEP 1097
++ E + + + EEE ++ LPE + L EEEEV+ L E E
Sbjct: 10087 KVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEE 10146
Query: 1098 LPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIF 1157
+PPE EV E ++ PEE +F+ + P+ + V
Sbjct: 10147 IPPEEEEVPPEEEYV-----------------PEEEEFVPEEEVLPEVKPKVPV------ 10183
Query: 1158 DRLLPAQIEKWKLKQKKKLERKKLI---KDMKAKIRVDTIAKRRAE--LILERDKKRREN 1212
PA + + K KK+ KK++ K+ +V + K+ E +IL ++++
Sbjct: 10184 ----PAPVPEIK----KKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV 10235
Query: 1213 VVRDDEE---ISEEELEEDNDDIENILEDEFPKDEE 1245
V ++ E ISEEE+ E+ IE + E P+ E
Sbjct: 10236 EVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPE 10271
Score = 59.3 bits (142), Expect = 3e-08
Identities = 105/439 (23%), Positives = 181/439 (41%), Gaps = 72/439 (16%)
Query: 681 EIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDE 740
EI K+ E+ ++ KKEE K E ++EE +R++ + + E T+ +E
Sbjct: 10189 EIKKKVTEK---KVVIPKKEEAPPAKVPEVPKKVEE--KRIILPKEEEVLPVEVTEEPEE 10243
Query: 741 EEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIP--KG 798
E I E E+ EEP + + EE VPE +AV E + E P K
Sbjct: 10244 EPIS--EEEIPEEPPSIEEV------EEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKV 10295
Query: 799 SKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILN 858
SK+ E EK+ V E P P+VP+ P K+ +L + EA +L
Sbjct: 10296 SKKIPE-EKVPVPVQKKEAPPAKVPEVPKKVPEKK------VLVPKKEAVPPAKGRTVLE 10348
Query: 859 LEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEG 918
+++ QE++ K E E EAEV+E EEEE E
Sbjct: 10349 EKVSVAFRQEVVVK----------------------ERLELEVVEAEVEEIPEEEEFHEV 10386
Query: 919 EDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKY-----REKIYYFSSAEAKEKF 973
E+ +E + H + + F + L+++ + + E+ + E++ F +A K
Sbjct: 10387 EEYFEEGEFH--EVEEF--IKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKG 10442
Query: 974 LEHPEDYVAHEE------PLKAPPLRICLVGPQGSGKTMCGR--QLAEKLNIFHIQFEEV 1025
E E + ++ P K PP ++ P+ K + ++ E+ + + EV
Sbjct: 10443 PEISEKIIPPKKPPTKVVPRKEPPAKV----PEVPKKIVVEEKVRVPEEPRVPPTKVPEV 10498
Query: 1026 LQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEE 1085
L K ++ +K P ++ + +E+ + V V + PEV T+
Sbjct: 10499 LPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPV----PPPKKPEVPPTKVP 10554
Query: 1086 EVIKSSLMEN---EPLPPE 1101
EV K+++ E E +PP+
Sbjct: 10555 EVPKAAVPEKKVPEAIPPK 10573
Score = 49.3 bits (116), Expect = 4e-05
Identities = 167/819 (20%), Positives = 305/819 (37%), Gaps = 138/819 (16%)
Query: 381 PYLLPPMPGPPCKVFILGPQYSG----KTTLCNMLAENYKGKVVDYAQLVQPRFDKARET 436
P +PP+ PP + + P+ + + + KVV + + PR + ++
Sbjct: 8954 PEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP 9013
Query: 437 LVENTIAEATAAAIKVVKEK--------LLRELQARKQAETALREFQRQYEKMEFGVFPM 488
T+ A A I V K + R+ + +K+ E + Q +++ +
Sbjct: 9014 PPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESF 9073
Query: 489 EATHSSIDEEGYIQGSQRDRGSSL-VDTEEAKTKSENVLHDQ------------AAKVDK 535
E + ++ E Y + ++ D EE K +++ +H++ +
Sbjct: 9074 EEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGY 9133
Query: 536 DDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVT---MIEETIKMS 592
D+G+E E +R ++V S + E A P V +IE+ K S
Sbjct: 9134 DEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTS 9193
Query: 593 QDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGI 652
+ + E+ + EV +++ + R P + + VK + K I
Sbjct: 9194 RRMEEEKV---QVTKVPEVSKKIVPQKPSRTP--------VQEEVIEVKVPAVHTKKMVI 9242
Query: 653 IPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEEL 712
+ + + S TE + QK+ + KI + + ++ K E K EE+
Sbjct: 9243 SEEKMFFASHTEEEVSVTVPEV--QKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEV 9300
Query: 713 -------RLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWL 765
++E ++ E+ K E ++ ++E +V E P+ +
Sbjct: 9301 APVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPP-KVPEVPKKPVPEEKIPV 9359
Query: 766 P----EEFEASEVPETEPEAVSEPIEETTVET-----------EIPKGS--KEGLEIEKL 808
P +E ++VPE + V+E E+ T+ T EIPK +E + +
Sbjct: 9360 PVAKKKEAPPAKVPEVQKGVVTE--EKITIVTQREESPPPAVPEIPKKKVPEERKPVPRK 9417
Query: 809 SETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQE 868
E V P P +P+ +EK+ + + K+ +E K + E ++
Sbjct: 9418 EEEVP----PPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEK 9473
Query: 869 LLQKVVETMEKPFQYTAWELTGED---YEEETEDYQTEAEVDEELEEEEE---------E 916
L V + +E T E++ E+ Y EE E +EE EEEEE E
Sbjct: 9474 LSFAVPQRVE----VTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVME 9529
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAK------ 970
E E+ + E K H ++ + +P E + +KI AK
Sbjct: 9530 EPEEYVVEEKLH----------IISKRVEAEPAEVTE--RQEKKIVLKPKIPAKIEEPPP 9577
Query: 971 EKFLEHPEDYVAHEE---PL----KAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFE 1023
K E P+ V ++ P+ K PP ++ P+ K + +++ K+ I+ E
Sbjct: 9578 AKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV----PEEPKKPVPEKKVPPKV----IKME 9629
Query: 1024 EVL-------------QEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEE 1070
E L +EK+L+ KK P E + A EE ++ K EEE
Sbjct: 9630 EPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVP--EEKVLKLKPKREEE 9687
Query: 1071 NTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSE 1109
K + +EE + + EP P I EV + E
Sbjct: 9688 PPAKVTEFRKRVVKEEKVSIEAPKREPQP--IKEVTIME 9724
Score = 48.9 bits (115), Expect = 5e-05
Identities = 191/902 (21%), Positives = 335/902 (37%), Gaps = 193/902 (21%)
Query: 673 RIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEA 732
R + KK+ ++ K R + E +K + + T E+ EEE E V
Sbjct: 9454 RAEVSKKTVVEEK---RFVAE-EKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVY 9509
Query: 733 EETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEE--FEASEVPETEPEAVSEPIEETT 790
E + E+EEE E E EV EEPE ++ EE S+ E EP V+E E+
Sbjct: 9510 REEEREEEEEAEVTEYEVMEEPE-------EYVVEEKLHIISKRVEAEPAEVTERQEKKI 9562
Query: 791 V-------------ETEIPKGSKEGLEIEKL------SETVVLPEFPEDSYPDVPEMEPF 831
V ++P+ K+ + +K+ E V P+ PE+ VPE
Sbjct: 9563 VLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPE---- 9618
Query: 832 KEKIGSFIILWKQLEATISEAYIKILNLEIA------------DRTPQELLQKVVETM-- 877
K+ I + + L A ++E +++I E R P+E + V E
Sbjct: 9619 KKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVL 9678
Query: 878 --------EKPFQYTAW-ELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERK-- 926
E P + T + + ++ + E + E + +E+ EE+E ++E
Sbjct: 9679 KLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVS 9738
Query: 927 -RHLGDTKHFCPVVLKENFILQPGNTEEAAKYRE-KIYYFSSAEAKEKFLEHPEDYV--- 981
+ + + + KE +P TEE +Y E + + E E+++ PE +
Sbjct: 9739 VQREEEYEEYEEYDYKEFEEYEP--TEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVK 9796
Query: 982 -AHEEPL----KAPPLRICLVG-PQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTE 1035
EEP+ KAPP ++ P+ ++L + ++V +EK+ +
Sbjct: 9797 PVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISIT 9856
Query: 1036 KKVGPEFEEDSENEQAAKQELEELAIQANVKVE--------------------------E 1069
K+ E++ E AAK ++ + A KV E
Sbjct: 9857 KR-----EKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFE 9911
Query: 1070 ENTKKQLPEVQLTEEEEVI---KSSLMENEPLP------PEILEVILSEWWLKEPI---- 1116
E + E + EEEE I + + E E +P PE+ + E P+
Sbjct: 9912 EEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKK 9971
Query: 1117 RSTGFILDGFPRYPEE-AQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQI---------- 1165
+ + P+ PEE L + P A +V + + + +P +
Sbjct: 9972 EAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAK 10031
Query: 1166 -----------EKWKLKQKKKLER---------KKLIKDMKAKIRV--------DTIAKR 1197
+K + KK+E KKLI + K V + K+
Sbjct: 10032 VPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKK 10091
Query: 1198 RAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEED---EE 1254
R + + + E V+ ++E + EEE+ + +++ E+ P++EE + EE+ EE
Sbjct: 10092 REPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEE 10151
Query: 1255 QETDAIERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARRNHIVQYTLNMKLKP 1314
+E E E E+F + L ++ ++ P+ I K
Sbjct: 10152 EEVPPEEEYVPE-EEEFVPEEEVLPEVKPKVP-VPAPVPEIK----------------KK 10193
Query: 1315 LVENRASIFEKCHPIPAPLAQKMLTFTYKYISSFGYWDPVKLSEGETIKPVENAENPIYP 1374
+ E + I +K PA + + K I L + E + PVE E P
Sbjct: 10194 VTEKKVVIPKKEEAPPAKVPEVPKKVEEKRII---------LPKEEEVLPVEVTEEPEEE 10244
Query: 1375 VIHRQYI--YFLSSKETKEKFMKNPIKYIRQPKPKPTVPIRIIIVGPPKSGKTTVAKKIT 1432
I + I S +E +E + I++ P+ P+ + PP V+KKI
Sbjct: 10245 PISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPP----AKVSKKIP 10300
Query: 1433 SE 1434
E
Sbjct: 10301 EE 10302
Score = 46.2 bits (108), Expect = 3e-04
Identities = 105/384 (27%), Positives = 159/384 (41%), Gaps = 59/384 (15%)
Query: 740 EEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGS 799
EEEI +E + EE E LPEE E +PE E E + E E E E+P
Sbjct: 10110 EEEIVPEEEVLPEEEEV--------LPEEEEV--LPEEE-EVLPEEEEIPPEEEEVPPEE 10158
Query: 800 KEGLEIEK-LSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILN 858
+ E E+ + E VLPE P VP P E ++ ++E + I
Sbjct: 10159 EYVPEEEEFVPEEEVLPEVK----PKVPVPAPVPE-----------IKKKVTEKKVVIPK 10203
Query: 859 LEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEE---LEEEEE 915
E A + K VE L E EE E+ +E E+ EE +EE EE
Sbjct: 10204 KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEE 10263
Query: 916 EEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLE 975
+ K+ + + P + + P AK +KI +K E
Sbjct: 10264 VAPPRVPEVIKKAVPEA----PTPVPKKVEAPP------AKVSKKIPEEKVPVPVQK-KE 10312
Query: 976 HPEDYVAHEEPLKAPPLRICL----VGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKL- 1030
P V E P K P ++ + P G+T+ L EK+++ Q E V++E+L
Sbjct: 10313 APPAKVP-EVPKKVPEKKVLVPKKEAVPPAKGRTV----LEEKVSVAFRQ-EVVVKERLE 10366
Query: 1031 --LLKTEKKVGPEFEEDSENEQAAKQ----ELEELAIQANVKVEEENTKKQLPEV-QLTE 1083
+++ E + PE EE E E+ ++ E+EE +VEEE+ +++ V ++ E
Sbjct: 10367 LEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE 10426
Query: 1084 EEEVIKSSLMENEPLPPEILEVIL 1107
EEV + P PEI E I+
Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKII 10450
Score = 36.6 bits (83), Expect = 0.24
Identities = 52/232 (22%), Positives = 91/232 (39%), Gaps = 37/232 (15%)
Query: 628 KYGGWIVDNCPIVKELWMALIKKGII------PDLVIYLSDTENNGKCLFNRIYLQKKSE 681
K GG + N K W L + G + + + + DT L+ + + E
Sbjct: 8476 KVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 8535
Query: 682 IDSKILERLLEELQKKKKEEEEARKATEEELRL-----EEENRRLLELMK-VKAKEAEE- 734
I+S + ++E +K++K E + R ++ L EEE ++EL+K V KE E+
Sbjct: 8536 IESNV-NLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKY 8594
Query: 735 ------TDN----------EDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETE 778
TD + +E E LE+ E + D + F + +TE
Sbjct: 8595 ARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTE 8654
Query: 779 PEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
P + + IE TV K+ + ++ + PE Y ++EP
Sbjct: 8655 PVTLIKDIENQTV-------LKDNDAVFEIDIKINYPEIKLSWYKGTEKLEP 8699
Score = 34.7 bits (78), Expect = 0.92
Identities = 42/171 (24%), Positives = 73/171 (42%), Gaps = 23/171 (13%)
Query: 679 KSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNE 738
++ ++ K+ +E+ K++ E E +A EE+ EEE + E + E +E
Sbjct: 10344 RTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFE------EGEFHE 10397
Query: 739 DEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEV--------PETEPEAVSEPIEETT 790
EE I+ ++ V EE R + E FEA EV P PE + I
Sbjct: 10398 VEEFIKLEQHRVEEEHRVEKVHR---VIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKK 10454
Query: 791 VETEIPKGSKEGLEIEKLSETVV------LPEFPEDSYPDVPEMEPFKEKI 835
T++ + ++ ++ + +V +PE P VPE+ P KE +
Sbjct: 10455 PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVV 10505
Score = 31.6 bits (70), Expect = 7.8
Identities = 40/142 (28%), Positives = 61/142 (42%), Gaps = 19/142 (13%)
Query: 598 EQPYEKHAEILQEVLGEVMEENKDRFPGAPKYG----GWIVDNCPIVKELWMALIKKGII 653
E YE + QE+L + F PK G G++ E ALI+K +
Sbjct: 1174 EADYELLMKSQQEML---YQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMA 1230
Query: 654 PDLVI---YLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEA-----R 705
D V+ Y+ D E + R+ EI+ +I++ LEEL ++ EE+ A
Sbjct: 1231 KDTVVVRTYVEDQEFHISSFEERLI----KEIEYRIIKTTLEELLEEDGEEKMAVDISES 1286
Query: 706 KATEEELRLEEENRRLLELMKV 727
+A E +N R+LE M V
Sbjct: 1287 EAVESGFDSRIKNYRILEGMGV 1308
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 69.7 bits (169), Expect = 3e-11
Identities = 122/583 (20%), Positives = 247/583 (42%), Gaps = 80/583 (13%)
Query: 695 QKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEP 754
+ ++K + ++A EL + R+L K + + A +++EG+ ++
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 755 EASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVL 814
S G E +A T+ + IEE T E ++ L +E T+
Sbjct: 168 HDSWKFAG----ELEQALSAVATQKKKADRYIEELTKE-------RDALSLELYRNTITD 216
Query: 815 PEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVV 874
E E + +++ + + + K+L+ + A + + PQ+ LQ
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL---------PQQQLQAEA 267
Query: 875 ETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEE-EEGEDKMKERKRHLGDTK 933
+ + K Q + +L + E E + + + ++ +EE+ +E E+K++E++ + + +
Sbjct: 268 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 327
Query: 934 HFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLR 993
++E EE + +E++ + E +EK E EE ++ R
Sbjct: 328 E----KIREQ--------EEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKMR----R 367
Query: 994 ICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK 1053
+ + + K R+L EK++ QEK+ + EK+ EE+ EQ +
Sbjct: 368 LEEMMWEKEEKI---RELEEKMHE---------QEKIREQEEKRQ----EEEKIREQEKR 411
Query: 1054 QELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLK 1113
QE E + K+ E+ K + E ++ +EE I E E + E E W +
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH----EQEKIREEEKRQEQEEMWRQ 467
Query: 1114 EP-IRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQ 1172
E IR I + E+ + + V+ Q + + + Q EK ++
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQ-----EEKVWRQEEKMHDQEEKIREQEEKMWRQE 522
Query: 1173 KKKLERKKLIKDMKAKIRV-DTIAKRRAELILERDKK--------RRENVVRDDEEISEE 1223
+K E+++ I++ + KIR + + + + E + E+++K R+E +R+ EE E
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582
Query: 1224 ELEEDNDDIENILE-DEFPKDEEEMSGEEDE---EQETDAIER 1262
+ E+ + E I E +E +++EEM E++E EQE E+
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 625
Score = 60.8 bits (146), Expect = 1e-08
Identities = 133/607 (21%), Positives = 242/607 (39%), Gaps = 109/607 (17%)
Query: 501 IQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKL 560
++G RD S L D+ + + E L A + K D E T +R + ++L
Sbjct: 156 LEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD--RYIEELTKERDALS----LEL 209
Query: 561 YSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEK--HAEIL---QEVLGEV 615
Y +T E+L +E A E + ++E K +N ++ K A++L Q++ E
Sbjct: 210 YRNTITDEEL-KEKNAKLQEKLQLVESE-KSEIQLNVKELKRKLERAKLLLPQQQLQAEA 267
Query: 616 MEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIY 675
K+ + K + +N ELW L + + K
Sbjct: 268 DHLGKELQSVSAKLQAQVEEN-----ELWNRL--------------NQQQEEKMWRQEEK 308
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELM---KVKAKEA 732
+Q+ E + E++ E+ +K +++EE+ R+ E EE+ RR E+M + K +
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRL 368
Query: 733 EETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVE 792
EE E EE+I E ++HE+ + E+ E + E EA EE E
Sbjct: 369 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMWRQEEKIRE 427
Query: 793 TEIP---KGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATI 849
E + K + EK+ E + E E+ + EM +EKI +W+Q E
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIREQEEIWRQKEKMH 485
Query: 850 SEAYIKILNLEI--ADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVD 907
+ I+ ++ + + +K+ E EK ++ E E E+ E + E +
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE--EKIREQEEKIREQEEKIREQE 543
Query: 908 EELEEEEEEEGE--DKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFS 965
E ++E+EE+ GE +KM+E+++ E+ + EKI
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEK-------------------MRRQEEKIREQEEKI---- 580
Query: 966 SAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEV 1025
E KEK E E EE ++
Sbjct: 581 -REQKEKIREQEEKIWEQEEKIRE------------------------------------ 603
Query: 1026 LQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEE 1085
QE+++ + E+K+ + E+ E E+ QE EE + K+ E+ + + E ++ E +
Sbjct: 604 -QEEMMQEQEEKMWEQEEKMCEQEE-KMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Query: 1086 EVIKSSL 1092
E +++++
Sbjct: 662 EHLEAAI 668
Score = 41.2 bits (95), Expect = 0.010
Identities = 76/357 (21%), Positives = 153/357 (42%), Gaps = 57/357 (15%)
Query: 940 LKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGP 999
L N I E+ AK +EK+ S +++ + + + LK R L+ P
Sbjct: 209 LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQL---------NVKELKRKLERAKLLLP 259
Query: 1000 QGSGKTMC---GRQLAEKLNIFHIQFEE-VLQEKLLLKTEKKVGPEFEEDSENEQAAKQE 1055
Q + G++L Q EE L +L + E+K+ + E+ E E+ QE
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI-QE 318
Query: 1056 LEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS---LMENEPLPPEILEVILSEWWL 1112
EE + K+ E+ K + E + E+EE ++ + E E + E++ W
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM---WEK 375
Query: 1113 KEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQ 1172
+E IR EE + + I ++ Q E+ +Q
Sbjct: 376 EEKIREL-----------EEKMH----------------EQEKIREQEEKRQEEEKIREQ 408
Query: 1173 KKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKK--RRENVVRDDEEISEEELEEDND 1230
+K+ E++ + + KIR + E I E++KK R+E + + E+I EEE ++ +
Sbjct: 409 EKRQEQEAKMWRQEEKIR------EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Query: 1231 DIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
++ ++E +++EE+ ++++ E + I + ++ + E + I+++ E+
Sbjct: 463 EMWR--QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 69.3 bits (168), Expect = 3e-11
Identities = 191/907 (21%), Positives = 359/907 (39%), Gaps = 150/907 (16%)
Query: 421 DYAQLVQPRFDKA---RETLVENTIAEATAAAIKVVKEKLLR---ELQARKQAETALREF 474
DYA+LV +K ++ V+ AE A +KV ++ R E+Q+ + TA E
Sbjct: 454 DYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA 513
Query: 475 QRQYEKMEFGVFPME--ATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAK 532
+Q + +F E + HS + + + R L+++E+ + E L Q
Sbjct: 514 AQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQD 573
Query: 533 VDKDDGKETGETFTFKRHSQDASQDV------KLYSDTAPTEDLI---EEVTADHPEVVT 583
+ + + + F HSQ A+Q +L+ A + I E+ A + +T
Sbjct: 574 ILEQNEALKAQIQQF--HSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLT 631
Query: 584 MIEETIKMSQDINF--EQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
EE +K Q++NF + +K + E E K + VK
Sbjct: 632 SKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEK-------------MQQSVYVK 678
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILE-RLLEELQKKKKE 700
+ + L+++ Q + EI +K+ E ++L + K K
Sbjct: 679 DDKIRLLEE--------------------------QLQHEISNKMEEFKILNDQNKALKS 712
Query: 701 EEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEV--HEEPEASH 758
E + + L E+ N+ ++E M+ +E +E EE +E ++V EE +
Sbjct: 713 EVQKLQT----LVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 768
Query: 759 DTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFP 818
T S L +E + + + + + + +EE G + +E E L ++
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVE-ELLEAELLKVANK 827
Query: 819 EDSYPDVP-EMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETM 877
E + D+ E++ KE+IG+ + L K + +I+ ++ NL ++ V+E
Sbjct: 828 EKTVQDLKQEIKALKEEIGN-VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEK 886
Query: 878 EKPFQYTAWELTGEDYEEETEDYQTEAE------VDEELEEEEEEEGEDKMKERKRHLGD 931
EK T L +D +EE E + + + E + EE E +KE++ L
Sbjct: 887 EKDLANTGKWL--QDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKR 944
Query: 932 TKHFCPVVLKENFILQPGNTE--EAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKA 989
+ +LKE T+ + + K++ + K++ + + HEE LK
Sbjct: 945 LE----AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV 1000
Query: 990 PPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENE 1049
++E+ + E+ K ++ ++K + E +
Sbjct: 1001 ---------------------ISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEA 1039
Query: 1050 QAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSE 1109
A E++ +Q V + ++Q+ V+L E +EV+K L +P + E
Sbjct: 1040 MEALASTEKM-LQDKVNKTSKERQQQVEAVEL-EAKEVLKK-LFPKVSVPSNLS---YGE 1093
Query: 1110 WWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWK 1169
W L GF + +E G G + ++ + D LL + EK+K
Sbjct: 1094 W------------LHGFEKKAKECM-AGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYK 1140
Query: 1170 LKQKK------KLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEE 1223
+ KL+R ++ K K++VD K K+ + + ++E+ E
Sbjct: 1141 SVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQEL--E 1190
Query: 1224 ELEEDNDDIENI------LEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHN 1277
L +N DIEN+ LE E K E E S E +E ++ L EL +K + D+++
Sbjct: 1191 RLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRE---LKDLLTELQKKLD-DSYS 1246
Query: 1278 LQIIQDE 1284
+ Q+E
Sbjct: 1247 EAVRQNE 1253
Score = 36.6 bits (83), Expect = 0.24
Identities = 135/687 (19%), Positives = 282/687 (41%), Gaps = 103/687 (14%)
Query: 649 KKGIIPDLVIYLSDT-ENNGKCLFNRI---YLQKKSEIDSKILERLLEELQKKKKEEEEA 704
+ GI+ D V ++ E+ N++ Y + +E+ K + EE+QKK E+
Sbjct: 425 ENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQA-- 482
Query: 705 RKATEEELRLEEENRRLLEL---MKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
AT+ +++L+E RR E+ ++ + E E + + + E EV DT
Sbjct: 483 --ATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTL 540
Query: 762 GSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDS 821
S E ++ E+E + V++ +E L+++ + + E +
Sbjct: 541 VSKQQLEQRLMQLMESEQKRVNK---------------EESLQMQ-------VQDILEQN 578
Query: 822 YPDVPEMEPFKEKIG---SFIILWKQLEATISEAYIKILNLEIA-----DR-TPQELLQK 872
+++ F +I S +L ++L I+E +I E + DR T +E K
Sbjct: 579 EALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
Query: 873 VVETMEKPFQYTAWELTGEDYEE-----ETEDYQTEAEVDEE----LEEEEEEEGEDKMK 923
++ M + +L E+ E E Q V ++ LEE+ + E +KM+
Sbjct: 639 DIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME 698
Query: 924 ERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAK--EKFLEHPEDYV 981
E K K V K ++ ++ + EK + K E+ LE V
Sbjct: 699 EFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV 758
Query: 982 A-HEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGP 1040
A EE L A + + S T + L K N + F +++E + EK
Sbjct: 759 ATKEEELNA-------IRTENSSLTKEVQDLKAKQN-DQVSFASLVEELKKVIHEKDGKI 810
Query: 1041 EFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS-------LM 1093
+ E+ + K +E +Q ++K E + K+++ VQL + +++ +S L+
Sbjct: 811 KSVEELLEAELLKVANKEKTVQ-DLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLL 869
Query: 1094 ENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDD 1153
+ + ++ +L E ++ + +TG L E + A +V
Sbjct: 870 KGKEEQMNTMKAVLEE--KEKDLANTGKWLQDLQEENESLK-----------AHVQEVAQ 916
Query: 1154 QDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENV 1213
++ + +Q E+ ++ K+K K ++ M + D +K + ++ + K ++
Sbjct: 917 HNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQ 976
Query: 1214 VRDDEEISEEELEE-----DNDDIENILEDEFPKDEEEMSGEEDE-EQETDAIER----- 1262
+ E++ ++ ++ ++++ ++ + E+E+SG +E + DA+E
Sbjct: 977 I---EQLKQQNYQQASSFPPHEELLKVISER----EKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 1263 --LRGELGEKFEADTHNLQIIQDELER 1287
LR + E EA +++QD++ +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVNK 1056
Score = 35.0 bits (79), Expect = 0.70
Identities = 84/438 (19%), Positives = 159/438 (36%), Gaps = 47/438 (10%)
Query: 406 TLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARK 465
T ++LAE + + + ++ D T E I+ + L E+Q +
Sbjct: 596 TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ 655
Query: 466 QAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENV 525
+ EKM+ V+ + ++E+ + S + +++ + KSE
Sbjct: 656 ALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSE-- 713
Query: 526 LHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHP--EVVT 583
+ V + K+ E ++ Q+ + +K + T LI+ T + + T
Sbjct: 714 VQKLQTLVSEQPNKDVVEQM--EKCIQEKDEKLKTVEELLET-GLIQVATKEEELNAIRT 770
Query: 584 MIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKEL 643
K QD+ +Q + L E L +V+ E + + + EL
Sbjct: 771 ENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEEL---------LEAEL 821
Query: 644 WMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSE--IDSKILERLLEELQKKKKEE 701
K+ + DL + + + L+K + I SK+ E L+ L K K+E+
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEE----IGNVQLEKAQQLSITSKVQE--LQNLLKGKEEQ 875
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDN--EDEEEIEGDELEVHEEPEASHD 759
KA EE K K+ T +D +E E + L+ H + A H+
Sbjct: 876 MNTMKAVLEE----------------KEKDLANTGKWLQDLQE-ENESLKAHVQEVAQHN 918
Query: 760 TRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVV----LP 815
+ + +FE E+ E E + +E E E SK L + E + +
Sbjct: 919 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIE 978
Query: 816 EFPEDSYPDVPEMEPFKE 833
+ + +Y P +E
Sbjct: 979 QLKQQNYQQASSFPPHEE 996
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 69.3 bits (168), Expect = 3e-11
Identities = 191/907 (21%), Positives = 359/907 (39%), Gaps = 150/907 (16%)
Query: 421 DYAQLVQPRFDKA---RETLVENTIAEATAAAIKVVKEKLLR---ELQARKQAETALREF 474
DYA+LV +K ++ V+ AE A +KV ++ R E+Q+ + TA E
Sbjct: 454 DYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA 513
Query: 475 QRQYEKMEFGVFPME--ATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAK 532
+Q + +F E + HS + + + R L+++E+ + E L Q
Sbjct: 514 AQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQD 573
Query: 533 VDKDDGKETGETFTFKRHSQDASQDV------KLYSDTAPTEDLI---EEVTADHPEVVT 583
+ + + + F HSQ A+Q +L+ A + I E+ A + +T
Sbjct: 574 ILEQNEALKAQIQQF--HSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLT 631
Query: 584 MIEETIKMSQDINF--EQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
EE +K Q++NF + +K + E E K + VK
Sbjct: 632 SKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEK-------------MQQSVYVK 678
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILE-RLLEELQKKKKE 700
+ + L+++ Q + EI +K+ E ++L + K K
Sbjct: 679 DDKIRLLEE--------------------------QLQHEISNKMEEFKILNDQNKALKS 712
Query: 701 EEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEV--HEEPEASH 758
E + + L E+ N+ ++E M+ +E +E EE +E ++V EE +
Sbjct: 713 EVQKLQT----LVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 768
Query: 759 DTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFP 818
T S L +E + + + + + + +EE G + +E E L ++
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVE-ELLEAELLKVANK 827
Query: 819 EDSYPDVP-EMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETM 877
E + D+ E++ KE+IG+ + L K + +I+ ++ NL ++ V+E
Sbjct: 828 EKTVQDLKQEIKALKEEIGN-VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEK 886
Query: 878 EKPFQYTAWELTGEDYEEETEDYQTEAE------VDEELEEEEEEEGEDKMKERKRHLGD 931
EK T L +D +EE E + + + E + EE E +KE++ L
Sbjct: 887 EKDLANTGKWL--QDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKR 944
Query: 932 TKHFCPVVLKENFILQPGNTE--EAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKA 989
+ +LKE T+ + + K++ + K++ + + HEE LK
Sbjct: 945 LE----AMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKV 1000
Query: 990 PPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENE 1049
++E+ + E+ K ++ ++K + E +
Sbjct: 1001 ---------------------ISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEA 1039
Query: 1050 QAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSE 1109
A E++ +Q V + ++Q+ V+L E +EV+K L +P + E
Sbjct: 1040 MEALASTEKM-LQDKVNKTSKERQQQVEAVEL-EAKEVLKK-LFPKVSVPSNLS---YGE 1093
Query: 1110 WWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWK 1169
W L GF + +E G G + ++ + D LL + EK+K
Sbjct: 1094 W------------LHGFEKKAKECM-AGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYK 1140
Query: 1170 LKQKK------KLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEE 1223
+ KL+R ++ K K++VD K K+ + + ++E+ E
Sbjct: 1141 SVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQEL--E 1190
Query: 1224 ELEEDNDDIENI------LEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHN 1277
L +N DIEN+ LE E K E E S E +E ++ L EL +K + D+++
Sbjct: 1191 RLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRE---LKDLLTELQKKLD-DSYS 1246
Query: 1278 LQIIQDE 1284
+ Q+E
Sbjct: 1247 EAVRQNE 1253
Score = 36.6 bits (83), Expect = 0.24
Identities = 135/687 (19%), Positives = 282/687 (41%), Gaps = 103/687 (14%)
Query: 649 KKGIIPDLVIYLSDT-ENNGKCLFNRI---YLQKKSEIDSKILERLLEELQKKKKEEEEA 704
+ GI+ D V ++ E+ N++ Y + +E+ K + EE+QKK E+
Sbjct: 425 ENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQA-- 482
Query: 705 RKATEEELRLEEENRRLLEL---MKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
AT+ +++L+E RR E+ ++ + E E + + + E EV DT
Sbjct: 483 --ATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTL 540
Query: 762 GSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDS 821
S E ++ E+E + V++ +E L+++ + + E +
Sbjct: 541 VSKQQLEQRLMQLMESEQKRVNK---------------EESLQMQ-------VQDILEQN 578
Query: 822 YPDVPEMEPFKEKIG---SFIILWKQLEATISEAYIKILNLEIA-----DR-TPQELLQK 872
+++ F +I S +L ++L I+E +I E + DR T +E K
Sbjct: 579 EALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
Query: 873 VVETMEKPFQYTAWELTGEDYEE-----ETEDYQTEAEVDEE----LEEEEEEEGEDKMK 923
++ M + +L E+ E E Q V ++ LEE+ + E +KM+
Sbjct: 639 DIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME 698
Query: 924 ERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAK--EKFLEHPEDYV 981
E K K V K ++ ++ + EK + K E+ LE V
Sbjct: 699 EFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV 758
Query: 982 A-HEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGP 1040
A EE L A + + S T + L K N + F +++E + EK
Sbjct: 759 ATKEEELNA-------IRTENSSLTKEVQDLKAKQN-DQVSFASLVEELKKVIHEKDGKI 810
Query: 1041 EFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS-------LM 1093
+ E+ + K +E +Q ++K E + K+++ VQL + +++ +S L+
Sbjct: 811 KSVEELLEAELLKVANKEKTVQ-DLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLL 869
Query: 1094 ENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDD 1153
+ + ++ +L E ++ + +TG L E + A +V
Sbjct: 870 KGKEEQMNTMKAVLEE--KEKDLANTGKWLQDLQEENESLK-----------AHVQEVAQ 916
Query: 1154 QDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENV 1213
++ + +Q E+ ++ K+K K ++ M + D +K + ++ + K ++
Sbjct: 917 HNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQ 976
Query: 1214 VRDDEEISEEELEE-----DNDDIENILEDEFPKDEEEMSGEEDE-EQETDAIER----- 1262
+ E++ ++ ++ ++++ ++ + E+E+SG +E + DA+E
Sbjct: 977 I---EQLKQQNYQQASSFPPHEELLKVISER----EKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 1263 --LRGELGEKFEADTHNLQIIQDELER 1287
LR + E EA +++QD++ +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVNK 1056
Score = 35.0 bits (79), Expect = 0.70
Identities = 84/438 (19%), Positives = 159/438 (36%), Gaps = 47/438 (10%)
Query: 406 TLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARK 465
T ++LAE + + + ++ D T E I+ + L E+Q +
Sbjct: 596 TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ 655
Query: 466 QAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENV 525
+ EKM+ V+ + ++E+ + S + +++ + KSE
Sbjct: 656 ALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSE-- 713
Query: 526 LHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHP--EVVT 583
+ V + K+ E ++ Q+ + +K + T LI+ T + + T
Sbjct: 714 VQKLQTLVSEQPNKDVVEQM--EKCIQEKDEKLKTVEELLET-GLIQVATKEEELNAIRT 770
Query: 584 MIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKEL 643
K QD+ +Q + L E L +V+ E + + + EL
Sbjct: 771 ENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEEL---------LEAEL 821
Query: 644 WMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSE--IDSKILERLLEELQKKKKEE 701
K+ + DL + + + L+K + I SK+ E L+ L K K+E+
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEE----IGNVQLEKAQQLSITSKVQE--LQNLLKGKEEQ 875
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDN--EDEEEIEGDELEVHEEPEASHD 759
KA EE K K+ T +D +E E + L+ H + A H+
Sbjct: 876 MNTMKAVLEE----------------KEKDLANTGKWLQDLQE-ENESLKAHVQEVAQHN 918
Query: 760 TRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVV----LP 815
+ + +FE E+ E E + +E E E SK L + E + +
Sbjct: 919 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIE 978
Query: 816 EFPEDSYPDVPEMEPFKE 833
+ + +Y P +E
Sbjct: 979 QLKQQNYQQASSFPPHEE 996
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 68.2 bits (165), Expect = 7e-11
Identities = 133/623 (21%), Positives = 264/623 (42%), Gaps = 74/623 (11%)
Query: 692 EELQKKKKEEEEAR-KATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEV 750
EELQ K +E + + K T+ E LEE R+ +L++ K AE+ E E E +E+
Sbjct: 852 EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 751 H------EEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLE 804
E E HD S + EE E +++ + E + + I++ + + +G+++ L+
Sbjct: 912 RLAAKKQELEEILHDLE-SRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 805 IEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLE---- 860
+EK++ + + E E+ +++ FI K +E I+E ++ E
Sbjct: 971 LEKVTAEAKIKKMEE-------EILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 861 --IADRTPQELLQKVVETMEKPFQYTAWE-------LTGEDYEEETEDYQTEAEVDE--- 908
R QE++ +E K + T E L GE + + + + +A++DE
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKL 1083
Query: 909 ELEEEEEE------EGEDKMKERKRHLGDTKHFCPVV--LKENFILQPGNTEEAAKYREK 960
+L ++EEE G+D+ + L + + L+E+F + + +A K +
Sbjct: 1084 QLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD 1143
Query: 961 IYYFSSAEAKEKFLEHPEDYVAHEEPLKAP-PLRICLVGPQGSGKTMCGRQLAEKLNIFH 1019
+ EA + LE D A ++ L+ + + +T + + H
Sbjct: 1144 L--SEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRH 1201
Query: 1020 IQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELE-ELAIQANVKVEEENTKKQLPE 1078
E L E+ L+ K+ E++ + + +EL E+ + VK E E+ +K+L +
Sbjct: 1202 ATALEELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKL-D 1258
Query: 1079 VQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGD 1138
Q+ E + + + E + L E L E LD EEA+ G
Sbjct: 1259 AQVQE----LHAKVSEGDRLRVE----------LAEKASKLQNELDNVSTLLEEAEKKGI 1304
Query: 1139 RGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRR 1198
+ F A ++ QD + L +K L R + +++ K ++ +
Sbjct: 1305 K--FAKDAASLESQLQDTQELLQEETRQKLNLS-----SRIRQLEEEKNSLQEQQEEEEE 1357
Query: 1199 AELILERDKKRRENVVRDDEEISEEELEEDNDDIENILE--DEFPKDEEEMSGE-EDEEQ 1255
A LE+ ++ + D +++++++D IE++ E + KD E +S E++
Sbjct: 1358 ARKNLEKQVLALQSQLAD----TKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKAL 1413
Query: 1256 ETDAIERLRGELGEKFEADTHNL 1278
D +E+ + L ++ + T +L
Sbjct: 1414 AYDKLEKTKNRLQQELDDLTVDL 1436
Score = 63.9 bits (154), Expect = 1e-09
Identities = 181/901 (20%), Positives = 367/901 (40%), Gaps = 107/901 (11%)
Query: 460 ELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSL-VDTEEA 518
ELQA+ + ++E Q K+E + ME H + EE I Q + L + EE
Sbjct: 853 ELQAKDEELLKVKEKQT---KVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 519 -------KTKSENVLHDQAAKVDKDDGKET---GETFTFKRHSQDASQDVKLYSDTAPTE 568
K + E +LHD ++V++++ + E + H QD + + + A +
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD-EEEGARQK 968
Query: 569 DLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPK 628
+E+VTA+ + +EE I + +D N + + K +++++ + E + + A
Sbjct: 969 LQLEKVTAEAK--IKKMEEEILLLEDQNSK--FIKEKKLMEDRIAECSSQLAEEEEKAKN 1024
Query: 629 YGGWIVDNCPIVKELWMALIK-----------KGIIPDLVIYLSDTENNGKCLFNRIYLQ 677
++ +L L K K + L D + + + LQ
Sbjct: 1025 LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1084
Query: 678 ---KKSEIDSKI-------------------LERLLEELQKKKKEEEEARKATEEELR-L 714
K+ E+ + L+ + ELQ+ + E+ +R E++ R L
Sbjct: 1085 LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDL 1144
Query: 715 EEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEV 774
EE LE +K + ++ +T +E E EV E +A + + + + +
Sbjct: 1145 SEE----LEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQR 1200
Query: 775 PETEPEAVSEPIEETTVETEIPKGSKEGLEI---EKLSETVVLPEFPEDSYPDVPEMEPF 831
T E +SE +E+ + +K+GLE E E VL + +S +++
Sbjct: 1201 HATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQ 1260
Query: 832 KEKIGSFIILWKQLEATISEAYIKILN-LEIADRTPQELLQKVVE------TMEKPFQYT 884
+++ + + +L ++E K+ N L+ +E +K ++ ++E Q T
Sbjct: 1261 VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDT 1320
Query: 885 AWELTGEDYEEETEDYQTEAEVDEE---LEEEEEEEGEDKMKERKRHLGDTKHFCPVVLK 941
EL E+ ++ +++EE L+E++EEE E + K+ L K
Sbjct: 1321 Q-ELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379
Query: 942 ENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQG 1001
+ L G E + ++K+ AEA + LE E +A+++ L+ R+
Sbjct: 1380 VDDDL--GTIESLEEAKKKL--LKDAEALSQRLE--EKALAYDK-LEKTKNRLQQELDDL 1432
Query: 1002 SGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAI 1061
+ RQ+A L +F+++L E EK + + E+ + +A +E E A+
Sbjct: 1433 TVDLDHQRQVASNLEKKQKKFDQLLAE------EKSISARYAEERDRAEAEAREKETKAL 1486
Query: 1062 QANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGF 1121
+EE K+ E Q + ++ + + + + E+ S+ L++ +
Sbjct: 1487 SLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT 1546
Query: 1122 ILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKL 1181
L+ +E Q DA + ++V+ Q + AQ E+ + ++ E KK
Sbjct: 1547 QLE---ELEDELQAT------EDAKLRLEVNMQ-----AMKAQFERDLQTRDEQNEEKK- 1591
Query: 1182 IKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFP 1241
++ + + + AEL ER ++ + EI ++LE + N DE
Sbjct: 1592 ------RLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA-QIEAANKARDEVI 1644
Query: 1242 KDEEEMSGE-EDEEQETDAIERLRGELGEKFEADTHNLQIIQDELERYLIPIISINGARR 1300
K ++ + +D ++E + R E+ + + L+ ++ E+ + + S ARR
Sbjct: 1645 KQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARR 1704
Query: 1301 N 1301
+
Sbjct: 1705 H 1705
Score = 38.9 bits (89), Expect = 0.049
Identities = 56/249 (22%), Positives = 103/249 (41%), Gaps = 24/249 (9%)
Query: 1037 KVGPEFEEDSENEQAAKQELEELAI-QANVKVEEENTKKQLPEVQLTEEEEVIKSSLMEN 1095
KV P + + E+ ++ E L + + KVE E + + QL EE+ ++ L
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE 899
Query: 1096 EPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQD 1155
L E E+ K+ + L+ EE + + +Q QD
Sbjct: 900 TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQI-----LQNEKKKMQAHIQD 954
Query: 1156 IFDRL-------LPAQIEKWKLKQK-KKLERKKLIKD-------MKAKIRVDTIAKRRAE 1200
+ ++L Q+EK + K KK+E + L+ + + K+ D IA+ ++
Sbjct: 955 LEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQ 1014
Query: 1201 LILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAI 1260
L E +K + +R+ +E+ +LEE E E K + ++ GE + Q D I
Sbjct: 1015 LAEEEEKAKNLAKIRNKQEVMISDLEERLKK-EEKTRQELEKAKRKLDGETTDLQ--DQI 1071
Query: 1261 ERLRGELGE 1269
L+ ++ E
Sbjct: 1072 AELQAQIDE 1080
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.8 bits (164), Expect = 1e-10
Identities = 111/597 (18%), Positives = 241/597 (40%), Gaps = 100/597 (16%)
Query: 695 QKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEP 754
+ ++K + ++A EL + R+L K + + A +++EG+ ++
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 755 EASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVL 814
S G E +A T+ + IEE T E ++ L +E T+
Sbjct: 229 HDSWKFAG----ELEQALSAVATQKKKADRYIEELTKE-------RDALSLELYRNTITD 277
Query: 815 PEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVV 874
E E + +++ + + + K+L+ + A + + PQ+ LQ
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL---------PQQQLQAEA 328
Query: 875 ETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEE-EEGEDKMKERKRHLGDTK 933
+ + K Q + +L + E E + + + ++ +EE+ +E E+K++E++ + + +
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE 388
Query: 934 HFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLR 993
++E EE + +E++ + E +EK E EE ++
Sbjct: 389 E----KIREQ--------EEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKMRR---- 428
Query: 994 ICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK 1053
QE+++ + E+K+ E+ E E+ +
Sbjct: 429 ---------------------------------QEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 1054 QE---LEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEW 1110
QE EE I+ K +E+ K E ++ E+EE I+ + E + W
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE---QEEKM-----------W 501
Query: 1111 WLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKL 1170
+E I I + R +E + + ++ Q + + + Q EK
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR 561
Query: 1171 KQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENV--VRDDEEISEEELEED 1228
+++K ++++ I++ + K+ R+ E I E+++K RE +R+ EE+++E+ E+
Sbjct: 562 QEEKMHDQEEKIREQEEKVW------RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 1229 NDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDEL 1285
+ E + E E E+E EE+ + +++R E EK +Q ++++
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIR-EQEEKIREQEEMMQEQEEKM 671
Score = 62.4 bits (150), Expect = 4e-09
Identities = 158/746 (21%), Positives = 293/746 (39%), Gaps = 137/746 (18%)
Query: 376 LLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGKVVDYAQLVQPRF----- 430
L+ P+P+L P P P + K T + LAE K ++ D+ P
Sbjct: 87 LMWPQPHL-PTHPHLPTHPHLPTHPMMSKETRQSKLAEA-KEQLTDHHPQTNPSVGTAAS 144
Query: 431 DKARETLVENTIAEATAA-----------AIKVVKEKLLRELQARKQAETALREFQRQYE 479
D ++ + T E T + A +E L REL+A+ +R Q
Sbjct: 145 DTKKKKINNGTNPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHT---IRILTCQKT 201
Query: 480 KMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGK 539
+++ ++ + ++ G RD S L D+ + + E L A + K D
Sbjct: 202 ELQMALYYSQHAVKQLE------GEARDLISRLHDSWKFAGELEQALSAVATQKKKAD-- 253
Query: 540 ETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQ 599
E T +R + ++LY +T E+L +E A E + ++E K +N ++
Sbjct: 254 RYIEELTKERDALS----LELYRNTITDEEL-KEKNAKLQEKLQLVESE-KSEIQLNVKE 307
Query: 600 PYEK--HAEIL---QEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIP 654
K A++L Q++ E K+ + K + +N ELW L
Sbjct: 308 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEEN-----ELWNRL------- 355
Query: 655 DLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRL 714
+ + K +Q+ E + E++ E+ +K +++EE+ R+ E
Sbjct: 356 -------NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 408
Query: 715 EEENRRLLELM---KVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEA 771
EE+ RR E+M + K + EE E EE+I E ++HE+ + E+
Sbjct: 409 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 468
Query: 772 SEVPETEPEAVSEPIEETTVETEIPKGSKEGL--EIEKLSETVVLPEFPEDSYPDVPEME 829
E + + + E+ + E + +E + + EK+ E + E E+ + EM
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE--EEKRQEQEEMW 526
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
+EKI +W+Q E KI E R +E + + E M
Sbjct: 527 RQEEKIREQEEIWRQKE--------KIHEQEEKIRKQEEKMWRQEEKMH----------- 567
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEE---EGEDKMKERKRHLGDTKHFCPVVLKENFIL 946
D EE+ + + + EE E+EE E E+K++E++ + +
Sbjct: 568 --DQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE------------- 612
Query: 947 QPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTM 1006
E+ + EK+ E +EK E E EE ++ +I
Sbjct: 613 -----EKMGEQEEKM-----CEQEEKMQEQEEKMRRQEEKIREQEKKI------------ 650
Query: 1007 CGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVK 1066
R+ EK+ QE+++ + E+K+ + E+ E E+ QE EE + K
Sbjct: 651 --REQEEKIRE---------QEEMMQEQEEKMWEQEEKMCEQEE-KMQEQEEKMRRQEEK 698
Query: 1067 VEEENTKKQLPEVQLTEEEEVIKSSL 1092
+ E+ + + E ++ E +E +++++
Sbjct: 699 MWEQEVRLRQQEEKMQEHQEHLEAAI 724
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 67.8 bits (164), Expect = 1e-10
Identities = 129/620 (20%), Positives = 245/620 (39%), Gaps = 114/620 (18%)
Query: 677 QKKSEIDSKILERLLEELQKKKKEEEEARKATEE------ELRLEEENRRLLELMKVKAK 730
Q + + ++ LERL ++++K +EA + +E + L +RR M+
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRR----MQNDTA 142
Query: 731 EAEETDNEDEEEIEGDELEVHE-EPEASHDTRGSWLPEEFEASEVPETEPEAVSEP---- 785
E E T+ E++ E + E+ E E + W E E E E E +P
Sbjct: 143 ENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGS 202
Query: 786 IEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQL 845
I E VE + + + E E ETVV+ + P+ E +E+ I +++
Sbjct: 203 IGENQVEVMVEEKTTESQE-----ETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM 257
Query: 846 EATISE-AYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEA 904
E E A + LE +R +++ +K + E+ E + EA
Sbjct: 258 EEEDKERAEAERARLEAEER------ERIKAEQDKKIADERARIEAEEKAAAQERERREA 311
Query: 905 EVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYF 964
E E + EEE+ E++ + +KE + AA+ R++I
Sbjct: 312 EERERMREEEKRAAEERQR----------------IKE-------EEKRAAEERQRIKEE 348
Query: 965 SSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEE 1024
A+E+ E+ A EE +A + EK + + +
Sbjct: 349 EKRAAEERQRIKEEEKRAAEERQRA------------------RAEEEEKAKVEEQKRNK 390
Query: 1025 VLQEKLLLKTEKKV-GPEFEEDSENEQAAKQELEELAIQANV---KVEEENTKKQLPEVQ 1080
L+EK E K+ G + E+ E + +++ +E +Q V + EE+ TK Q +
Sbjct: 391 QLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK 450
Query: 1081 LTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRG 1140
L E++ K +++E + + KEP EE + DR
Sbjct: 451 LQEDKPTFKKEEIKDEKIKKD-----------KEP--------------KEEVKSFMDR- 484
Query: 1141 FFPDAAVFIQVDDQD---IFDRLLPAQIEKWKLKQKKKLERKKL--IKDMKAKIRVDTIA 1195
F +V Q+ + +L + + + ++ K+ ++A R++ +
Sbjct: 485 ----KKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELR 540
Query: 1196 KRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEE-----MSGE 1250
+RR E E +K ++ + + + EEL++ ++ +LE+E + ++E + E
Sbjct: 541 RRRGETESEEFEKLKQK--QQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREE 598
Query: 1251 EDEEQETDAIERLRGELGEK 1270
E++ + + IER R E EK
Sbjct: 599 EEKRRLKEEIERRRAEAAEK 618
Score = 57.0 bits (136), Expect = 2e-07
Identities = 86/334 (25%), Positives = 150/334 (44%), Gaps = 60/334 (17%)
Query: 688 ERLLEELQKKKKEE----EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEI 743
+R EE Q+ K+EE EE ++ EEE R EE +R+ E K A+E + E+EE+
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Query: 744 EGDE----LEVHEEPEASHDT--RGSWLPEEFEASEVPETEPEAVSEPIEETTVETE-IP 796
+ +E ++ E+ A +T +G + ++ E V E +A + ++ ++ +
Sbjct: 382 KVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWV--NEKKAQEDKLQTAVLKKQGEE 439
Query: 797 KGSKEGLEIEKLSETVVLPEFPEDSYPD---VPEMEPFKEKIGSFI-------------- 839
KG+K + EKL E P F ++ D + EP KE++ SF+
Sbjct: 440 KGTKVQAKREKLQED--KPTFKKEEIKDEKIKKDKEP-KEEVKSFMDRKKGFTEVKSQNG 496
Query: 840 ----ILWKQLEATISEAYIKI-LNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYE 894
K E T S + ++ + A+ PQ K +E + + E E++E
Sbjct: 497 EFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR----RRGETESEEFE 552
Query: 895 EETEDYQTEAEVDEELEEEEEEEG---EDKMKERKRHLGDTKHFCPVVLKENFILQPGNT 951
+ + Q A EEL+++ EE E++ + RK+ D K L+E
Sbjct: 553 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK------LREE-------- 598
Query: 952 EEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEE 985
EE + +E+I AEA EK + PED ++ ++
Sbjct: 599 EEKRRLKEEIER-RRAEAAEKRQKMPEDGLSDDK 631
Score = 47.8 bits (112), Expect = 1e-04
Identities = 61/248 (24%), Positives = 113/248 (45%), Gaps = 25/248 (10%)
Query: 1041 EFEEDSENEQAAKQELEEL-----AIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMEN 1095
E EE SE+ Q + E+EE + Q N + E KK+ E + EEE+ + S+ EN
Sbjct: 148 EKEEKSESRQE-RYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 1096 EPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQD 1155
+ +EV++ E + + L EE + +R D + +++
Sbjct: 207 Q------VEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEE 260
Query: 1156 IFDRLLPAQIEKWKL----KQKKKLERKKLIKDMKAKIRVDTIA-----KRRAELILERD 1206
+R A+ E+ +L +++ K E+ K I D +A+I + A +RR ER
Sbjct: 261 DKER---AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERM 317
Query: 1207 KKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE 1266
++ + + + I EEE + ++ + I E+E EE +E+E++ + +R R E
Sbjct: 318 REEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAE 376
Query: 1267 LGEKFEAD 1274
EK + +
Sbjct: 377 EEEKAKVE 384
Score = 38.9 bits (89), Expect = 0.049
Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 23/114 (20%)
Query: 677 QKKSEIDSKILERLLE-------ELQKKKKEEEEARKATEEE------------LRLEEE 717
+++ E +S+ E+L + EL++ KK+ EE RK EEE LR EEE
Sbjct: 541 RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE 600
Query: 718 NRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEA 771
RRL E ++ + EA E +++ D L ++P +GS L E A
Sbjct: 601 KRRLKEEIERRRAEAA----EKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERA 650
Score = 38.1 bits (87), Expect = 0.083
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 10/87 (11%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELR--LEEENRRLLELMKVKAKEAE 733
L+KK E K+LE EE Q++K+EE + + EEE R EE RR E + + K E
Sbjct: 568 LKKKREERRKVLE---EEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Query: 734 ETDNEDEEEI-----EGDELEVHEEPE 755
+ ++D++ +G L++ E E
Sbjct: 625 DGLSDDKKPFKCFTPKGSSLKIEERAE 651
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1464 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1522
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1523 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1577
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1578 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1637
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1638 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1697
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1698 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1744
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1860
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1861 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1912
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1913 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1970
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1971 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2030
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2031 ESARQLQLAQEAAQKRL 2047
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1754 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1812
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1813 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1932
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1933 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 1974
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 1975 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2028
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2089 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2132
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2133 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2189
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2190 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2241
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2242 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2294
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2295 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2348
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2349 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2406 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2465
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2466 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2523
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2524 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2583
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2584 EELLAEENQRLREQLQLLEEQ 2604
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1752 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1802
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1803 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1854
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1855 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1912
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1913 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1959
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1960 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 2013
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 2014 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2068
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2069 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2121 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2175
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2176 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2234
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2266
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2270 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2329
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2330 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2388
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2389 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2445
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2506 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2563 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2622
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2623 TKTLPNGRDALDGPAAEAEPE 2643
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1408 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1467
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1468 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1526
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1527 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1581
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1582 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1641
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1642 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1701
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1702 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1748
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1749 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1808
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1809 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1864
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1865 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1916
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1917 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1974
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1975 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2034
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2035 ESARQLQLAQEAAQKRL 2051
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1758 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1816
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1817 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1876
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1877 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1936
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1937 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 1978
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 1979 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2032
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2033 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2092
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2093 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2136
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2137 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2193
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2194 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2245
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2246 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2298
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2299 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2352
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2353 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2409
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2410 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2469
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2470 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2527
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2528 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2587
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2588 EELLAEENQRLREQLQLLEEQ 2608
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1696 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1755
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1756 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1806
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1807 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1858
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1859 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1916
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1917 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1963
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1964 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 2017
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 2018 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2072
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2073 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2124
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2125 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2179
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2180 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2238
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2239 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2270
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2274 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2333
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2334 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2392
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2393 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2449
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2450 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2510 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2566
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2567 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2626
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2627 TKTLPNGRDALDGPAAEAEPE 2647
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1404 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1463
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1464 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1522
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1523 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1577
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1578 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1637
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1638 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1697
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1698 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1744
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1860
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1861 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1912
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1913 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1970
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1971 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2030
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2031 ESARQLQLAQEAAQKRL 2047
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1754 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1812
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1813 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1872
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1932
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1933 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 1974
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 1975 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2028
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2029 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2088
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2089 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2132
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2133 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2189
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2190 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2241
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2242 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2294
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2295 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2348
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2349 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2405
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2406 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2465
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2466 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2523
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2524 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2583
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2584 EELLAEENQRLREQLQLLEEQ 2604
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1751
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1752 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1802
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1803 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1854
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1855 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1912
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1913 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1959
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1960 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 2013
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 2014 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2068
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2069 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2120
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2121 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2175
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2176 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2234
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2235 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2266
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2270 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2329
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2330 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2388
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2389 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2445
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2446 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2506 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2562
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2563 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2622
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2623 TKTLPNGRDALDGPAAEAEPE 2643
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1372 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1431
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1432 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1490
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1491 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1545
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1546 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1605
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1606 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1665
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1666 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1712
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1713 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1772
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1773 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1828
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1829 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1880
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1881 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1938
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1939 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 1998
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 1999 ESARQLQLAQEAAQKRL 2015
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1722 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1780
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1781 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1840
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1841 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1900
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1901 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 1942
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 1943 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 1996
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 1997 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2056
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2057 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2100
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2101 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2157
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2158 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2209
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2210 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2262
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2263 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2316
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2317 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2373
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2374 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2433
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2434 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2491
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2492 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2551
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2552 EELLAEENQRLREQLQLLEEQ 2572
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1660 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1719
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1720 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1770
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1771 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1822
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1823 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1880
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1881 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1927
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1928 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 1981
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 1982 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2036
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2037 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2088
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2089 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2143
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2144 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2202
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2203 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2234
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2238 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2297
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2298 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2356
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2357 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2413
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2414 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2473
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2474 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2530
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2531 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2590
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2591 TKTLPNGRDALDGPAAEAEPE 2611
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1541 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1600
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1601 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1659
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1660 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1714
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1715 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1774
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1775 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1834
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1835 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1881
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1882 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1941
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1942 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1997
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1998 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 2049
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 2050 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 2107
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 2108 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2167
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2168 ESARQLQLAQEAAQKRL 2184
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1891 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1949
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1950 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 2009
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 2010 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 2069
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 2070 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 2111
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 2112 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2165
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2166 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2225
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2226 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2269
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2270 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2326
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2327 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2378
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2379 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2431
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2432 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2485
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2486 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2542
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2543 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2602
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2603 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2660
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2661 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2720
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2721 EELLAEENQRLREQLQLLEEQ 2741
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1829 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1888
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1889 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1939
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1940 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1991
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1992 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 2049
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 2050 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 2096
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 2097 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 2150
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 2151 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2205
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2206 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2257
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2258 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2312
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2313 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2371
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2372 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2403
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2407 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2466
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2467 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2525
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2526 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2582
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2583 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2642
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2643 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2699
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2700 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2759
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2760 TKTLPNGRDALDGPAAEAEPE 2780
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1382 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1441
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1442 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1500
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1501 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1555
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1556 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1615
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1616 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1675
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1676 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1722
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1723 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1782
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1783 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1838
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1839 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1890
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1891 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1948
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1949 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2008
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2009 ESARQLQLAQEAAQKRL 2025
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1732 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1790
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1791 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1850
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1851 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1910
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1911 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 1952
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 1953 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2006
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2007 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2066
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2067 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2110
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2111 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2167
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2168 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2219
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2220 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2272
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2273 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2326
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2327 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2383
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2384 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2443
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2444 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2501
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2502 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2561
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2562 EELLAEENQRLREQLQLLEEQ 2582
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1670 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1729
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1730 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1780
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1781 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1832
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1833 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1890
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1891 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1937
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1938 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 1991
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 1992 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2046
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2047 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2098
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2099 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2153
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2154 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2212
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2213 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2244
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2248 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2307
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2308 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2366
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2367 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2423
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2424 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2483
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2484 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2540
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2541 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2600
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2601 TKTLPNGRDALDGPAAEAEPE 2621
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1390 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1449
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1450 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1508
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1509 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1563
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1564 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1623
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1624 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1683
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1684 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1730
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1731 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1790
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1791 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1846
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1847 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1898
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1899 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1956
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1957 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2016
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2017 ESARQLQLAQEAAQKRL 2033
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1740 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1798
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1799 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1858
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1859 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1918
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1919 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 1960
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 1961 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2014
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2015 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2074
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2075 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2118
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2119 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2175
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2176 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2227
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2228 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2280
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2281 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2334
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2335 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2391
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2392 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2451
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2452 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2509
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2510 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2569
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2570 EELLAEENQRLREQLQLLEEQ 2590
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1678 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1737
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1738 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1788
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1789 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1840
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1841 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1898
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1899 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1945
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1946 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 1999
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 2000 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2054
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2055 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2106
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2107 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2161
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2162 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2220
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2221 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2252
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2256 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2315
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2316 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2374
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2375 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2431
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2432 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2491
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2492 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2548
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2549 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2608
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2609 TKTLPNGRDALDGPAAEAEPE 2629
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 66.6 bits (161), Expect = 2e-10
Identities = 140/677 (20%), Positives = 269/677 (39%), Gaps = 97/677 (14%)
Query: 677 QKKSEIDSKILERLL-EELQKKKKEEE--------EARKATEEELRLEEENRRL------ 721
++++ +D++ +R + EELQ+ ++ E +A A LR+EEE R +
Sbjct: 1431 REEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEA 1490
Query: 722 -----------LELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFE 770
L+ ++ +A+EAE + +EE E +V +E + L +
Sbjct: 1491 TERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVE-LASRVK 1549
Query: 771 ASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEP 830
A E + + +EE ++ E + E+E+ + V E + S E E
Sbjct: 1550 AEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRS----AEAE- 1604
Query: 831 FKEKIGSFIILWKQLEATISEAYIKILNL-EIADRTPQELLQKVVETMEKPFQYTAWELT 889
+ K SF QLE ++ E ++ + L E A+R Q+ + E + W+L
Sbjct: 1605 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLK 1664
Query: 890 GED------YEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKEN 943
+ EE ++ A+ + E ++EE E + + + + L++
Sbjct: 1665 ANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQ 1724
Query: 944 FILQPGNTEE-AAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L G ++ A +E I + E E+ + E+ +A + + +
Sbjct: 1725 RQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELAR-------------LQREAA 1771
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK-QELEELAI 1061
T ++L +L + E +L K + E + E + +A + +EL E A
Sbjct: 1772 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1831
Query: 1062 QANVKVEEENTKKQLPEV----QLTEEEEVIKSSLM---ENEPLPPEILEVILSEWWLKE 1114
+ EE ++QL E Q E E V+ L E L E E+ L E KE
Sbjct: 1832 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTE-AEIALKE---KE 1887
Query: 1115 PIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPA---QIEKWK-- 1169
+ R E+ F R + A + D ++ +L A ++E+ K
Sbjct: 1888 AEN------ERLRRLAEDEAF--QRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1939
Query: 1170 ----LKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEEL 1225
L+Q++++E + I +KA K EL L R + E+ +R E+ E
Sbjct: 1940 VEDTLRQRRQVEEE--ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAA 1997
Query: 1226 EEDN--DDIENILEDEFPKDEEEMSGEEDEEQETDA----IERLRGE------LGEKFEA 1273
+ + E + + ++ ++ EE+ ++ A +ERL+ + L E+ E
Sbjct: 1998 RQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQ 2057
Query: 1274 DT-HNLQIIQDELERYL 1289
++ LQ+ Q+ ++ L
Sbjct: 2058 ESARQLQLAQEAAQKRL 2074
Score = 51.2 bits (121), Expect = 9e-06
Identities = 169/921 (18%), Positives = 359/921 (38%), Gaps = 150/921 (16%)
Query: 444 EATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQG 503
EA A ++ E LL ++ + E +Q + E G F E + +
Sbjct: 1781 EAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF-RELAEEAARLRALAEE 1839
Query: 504 SQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSD 563
++R R + D + ++E VL ++ A + + +T K + + +L D
Sbjct: 1840 AKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAED 1899
Query: 564 TAPTEDLIEEVTADHPEVVT-------------------MIEETIKMSQDI--------- 595
A +EE A H + ++E+T++ + +
Sbjct: 1900 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1959
Query: 596 NFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPD 655
+FE+ AE+ E LG + +D + EL A ++
Sbjct: 1960 SFEKAAAGKAELELE-LGRIRSNAEDTLRSKEQ------------AELEAARQRQ----- 2001
Query: 656 LVIYLSDTENNGKCLFNRIYLQKKSEIDS-KILERLLEELQKKKKEEEEARKATEEELRL 714
++ E + R+ +E ++ + + LEE+++ K + EEAR+ E R
Sbjct: 2002 ---LAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRE---RA 2055
Query: 715 EEENRRLLELMKVKAK---EAEETDNEDEEEIEGDELE--VHEEPEASHDTRGSWLPEEF 769
E+E+ R L+L + A+ +AEE + + + EL+ + +E RG
Sbjct: 2056 EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARR 2115
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
A E E +A E E + ++ E E+L ++ E+ + +
Sbjct: 2116 AAEEAEEARVQA----------EREAAQSRRQVEEAERLKQSA------EEQAQARAQAQ 2159
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELT 889
EK+ +Q A ++A L + A E +K E + ELT
Sbjct: 2160 AAAEKLRKEA---EQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELT 2216
Query: 890 GEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPG 949
+ E D+Q +DEEL+ + E E R+R + + F V E
Sbjct: 2217 TLRLQLEETDHQKNL-LDEELQRLKAEATE---AARQRSQVEEELFSVRVQMEEL----S 2268
Query: 950 NTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGR 1009
+ + + + ++FL+ + + + + R+ + + + R
Sbjct: 2269 KLKARIEAENRALILRDKDNTQRFLQEEAEKM---KQVAEEAARLSVAAQEAARL----R 2321
Query: 1010 QLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEE 1069
QLAE+ + + L EK+L EK + + E Q+ +ELA + +++E
Sbjct: 2322 QLAEE----DLAQQRALAEKML--KEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQE 2375
Query: 1070 ENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEI-LEVILSEWWLKEPIRSTGFILDGFPR 1128
+ K+Q+ + QL EE + + +L E+ E + + E R+ + R
Sbjct: 2376 D--KEQMAQ-QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQR 2432
Query: 1129 YPEEAQFLGDRGFFPDAAVFIQV---------------DDQDIFDRLLPAQIEKWKLKQK 1173
+ ++A+ +G++ + A +V D + + + + + EK KL+Q+
Sbjct: 2433 FRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQE 2492
Query: 1174 KKL-----------ERKKLIKDMKA-----KIRVDTIAKRRAELILERDKKRRENV---- 1213
KL ++++L+++ +A D++ +R E +E++K + E +
Sbjct: 2493 AKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2550
Query: 1214 ------VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE- 1266
+R++++ ++++E++ + +E+ + E G +++E +E+ R +
Sbjct: 2551 VAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQ 2610
Query: 1267 ---LGEKFEADTHNLQIIQDE 1284
L E+ + LQ+++++
Sbjct: 2611 EELLAEENQRLREQLQLLEEQ 2631
Score = 47.0 bits (110), Expect = 2e-04
Identities = 132/632 (20%), Positives = 253/632 (40%), Gaps = 91/632 (14%)
Query: 692 EELQKKKKEEE---EARKATEEEL---RLE----EENRRLLELMKVKAKEAEETDNEDEE 741
+EL+K+++ E + R A E+EL R E E+ R+LLE + + + +
Sbjct: 1719 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ 1778
Query: 742 EIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKE 801
E+E + +V E E ++ E SE + EA + E ++E
Sbjct: 1779 ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL---------AEE 1829
Query: 802 GLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEI 861
+ L+E + E + +++ + +L ++L A I EA EI
Sbjct: 1830 AARLRALAEEA-------KRQRQLAEEDAARQRAEAERVLAEKL-AAIGEATRLKTEAEI 1881
Query: 862 A---DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED--YQTEAEVDEELEEEEEE 916
A E L+++ E ++ FQ E ++ + E+ Q D ELE ++
Sbjct: 1882 ALKEKEAENERLRRLAE--DEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGL 1939
Query: 917 EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKI-----YYFSSAEAKE 971
ED +++R++ ++E + + E+AA + ++ S+AE
Sbjct: 1940 V-EDTLRQRRQ------------VEEEILALKASFEKAAAGKAELELELGRIRSNAEDTL 1986
Query: 972 KFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLL 1031
+ E E A + L A R + K++ + A + Q + L+E
Sbjct: 1987 RSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR------QRKAALEEVER 2040
Query: 1032 LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS 1091
LK + + E +E E A + +L + A Q ++ EE K VQ E+E ++ +
Sbjct: 2041 LKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEE---KAHAFAVQQKEQE--LQQT 2095
Query: 1092 LMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQV 1151
L + + +L+ + E E R + R E + R +A Q
Sbjct: 2096 LQQEQ----SVLDQLRGE---AEAARRAAEEAEE-ARVQAEREAAQSRRQVEEAERLKQS 2147
Query: 1152 DDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRE 1211
++ R AQ KL+++ + E + + +A +R K+ A+ +E+ KK E
Sbjct: 2148 AEEQAQAR-AQAQAAAEKLRKEAEQEAARRAQAEQAALR----QKQAADAEMEKHKKFAE 2202
Query: 1212 NVVRDDEEISEE------ELEEDNDDIENILEDEFPK-DEEEMSGEEDEEQETDAIERLR 1264
+R ++ +E +LEE D +N+L++E + E Q + + +R
Sbjct: 2203 QTLRQKAQVEQELTTLRLQLEE-TDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVR 2261
Query: 1265 GELGE----KFEADTHNLQII---QDELERYL 1289
++ E K + N +I +D +R+L
Sbjct: 2262 VQMEELSKLKARIEAENRALILRDKDNTQRFL 2293
Score = 39.3 bits (90), Expect = 0.037
Identities = 76/381 (19%), Positives = 155/381 (40%), Gaps = 19/381 (4%)
Query: 412 AENYKGKVVDYAQLVQPRFDKAR-ETLVENTIAEATAAAIKVVKEKLLRELQA-RKQAET 469
AE K + A+L + AR L E +A+ A A K++KEK+ +A R +AE
Sbjct: 2297 AEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2356
Query: 470 ALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQ 529
L + Q++ + + + + QG QR + E ++E L +
Sbjct: 2357 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAER-LKLR 2415
Query: 530 AAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDL--------IEEVTADHPEV 581
A++ + + + F++ +++ + KL+ T++ I+ +DH +
Sbjct: 2416 VAEMSRAQARAEEDAQRFRKQAEEIGE--KLHRTELATQEKVTLVQTLEIQRQQSDH-DA 2472
Query: 582 VTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
+ E ++ ++ Q K ++ E + V +E + A + + + +
Sbjct: 2473 ERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEE 701
E ++ K + ++ + + + Q++ E + + L +EE ++++ E
Sbjct: 2533 ERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEA 2589
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
EE + +EEL+ E+ RR E + + + + EE L EE AS
Sbjct: 2590 EEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAA 2649
Query: 762 GSWLPEEFEASEVP--ETEPE 780
LP +A + P E EPE
Sbjct: 2650 TKTLPNGRDALDGPAAEAEPE 2670
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 66.2 bits (160), Expect = 3e-10
Identities = 93/383 (24%), Positives = 160/383 (41%), Gaps = 75/383 (19%)
Query: 680 SEIDSKILERLLEELQKKKKEEEEAR-------KATEE---ELRLEEENRRLLELMKVKA 729
+E D K ++ ++ +K++KE+E+ + KA +E +L+ EEE ++ E ++K
Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKR 368
Query: 730 KEAEETDNEDEEEIEGDELEVHEEPEASHDTR----GSWLPE----------------EF 769
E E ++EE +E ++ E ++ E R G L + +
Sbjct: 369 LEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQA 428
Query: 770 EASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEME 829
+ EVP + PI E +IP+ E E+ + E E E P+ E
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQ-QLESKEVSESMELCAAVEVMEQGVPEKEETP 487
Query: 830 PFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELL-QKV-VETMEKPFQYTAWE 887
P E + E +A + +D +++ KV +E E P
Sbjct: 488 PPVE---------PEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENP------- 531
Query: 888 LTGEDYEEETEDYQTEAEVDEELEEEEEEEG---------EDKMKERKRHLGDTKHFCPV 938
EE E+ + E E DEE EEEEEEEG ED+ ++ G T P
Sbjct: 532 -------EEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP- 583
Query: 939 VLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVG 998
KE ++++ E+ Y + +++ LEH ++ + E L+AP IC++G
Sbjct: 584 -SKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKN--VNTEKLRAP--IICVLG 638
Query: 999 PQGSGKTMCGRQLAEKLNIFHIQ 1021
+GKT ++ +KL H+Q
Sbjct: 639 HVDTGKT----KILDKLRHTHVQ 657
Score = 55.1 bits (131), Expect = 7e-07
Identities = 86/386 (22%), Positives = 161/386 (41%), Gaps = 55/386 (14%)
Query: 908 EELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSA 967
E+ E E ++ E+K K RK LKE L+ G +++ K +E F
Sbjct: 234 EKKERERKKRDEEKAKLRK-------------LKEKEELETGKKDQS-KQKESQRKFEEE 279
Query: 968 EAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQ 1027
K K A EE + P AE N + ++ +
Sbjct: 280 TVKSKVTVDTGVIPASEEKAETPTA-------------------AEDDN----EGDKKKK 316
Query: 1028 EKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEV 1087
+K +KK G + E++ E ++ + + +A K++EE +++ E + + E
Sbjct: 317 DK-----KKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371
Query: 1088 IKSSLMENEPLPPEILE-VILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAA 1146
+++ E E L E E E KE ++ G +L R EA+ + A
Sbjct: 372 LEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQR---EARARAEATLKLLQA 428
Query: 1147 VFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAEL----- 1201
++V +D + P +K + K ++LE K++ + M+ V+ + + E
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPP 488
Query: 1202 -ILERDKKRRENVVRDDEEI--SEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETD 1258
+ +++ E+ DD E S+EE E+ + +I E P++EEE EE+E++E++
Sbjct: 489 PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESE 548
Query: 1259 AIERLRGELGEKFEADTHNLQIIQDE 1284
E GE E E D + ++ ++
Sbjct: 549 EEEEEEGE-SEGSEGDEEDEKVSDEK 573
Score = 51.2 bits (121), Expect = 9e-06
Identities = 96/447 (21%), Positives = 176/447 (39%), Gaps = 74/447 (16%)
Query: 662 DTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRL 721
+ E+N K + R + E + E L +KK ++ + E ++ + ++
Sbjct: 166 EDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKI 225
Query: 722 LELMKVKAKEAE-ETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE 780
+ + KA++ E E DEE+ + +L+ EE E + S+ E++ +
Sbjct: 226 KTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK----------DQSKQKESQRK 275
Query: 781 AVSEPIE-ETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFI 839
E ++ + TV+T + S+E E P ED + + K+K G
Sbjct: 276 FEEETVKSKVTVDTGVIPASEEKAET---------PTAAEDDNEGDKKKKDKKKKKGEKE 326
Query: 840 ILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETED 899
K+ + S+A +K + +A +E QK E E+ + E+
Sbjct: 327 EKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE---------------EERIKRLEE 371
Query: 900 YQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYRE 959
+ + + +E LE+E+ E + K KERK L KE +L E A+
Sbjct: 372 LEAKRKEEERLEQEKRERKKQKEKERKERLK----------KEGKLLTKSQREARAR--- 418
Query: 960 KIYYFSSAEAKEKFLEHP------EDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAE 1013
AEA K L+ +D + + P+ R + PQ + ++++E
Sbjct: 419 -------AEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKI--PQ----QLESKEVSE 465
Query: 1014 KLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEEN-- 1071
+ + EV+++ + K E E EE+ + E A + E +A + E N
Sbjct: 466 SMEL--CAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKV 523
Query: 1072 --TKKQLPEVQLTEEEEVIKSSLMENE 1096
K+ PE + EEEE + E E
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEE 550
Score = 46.2 bits (108), Expect = 3e-04
Identities = 89/399 (22%), Positives = 155/399 (38%), Gaps = 79/399 (19%)
Query: 432 KARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEAT 491
KA + E + A ++ +KEK EL+ K+ ++ +E QR++E+ E
Sbjct: 232 KAEKKERERKKRDEEKAKLRKLKEK--EELETGKKDQSKQKESQRKFEE--------ETV 281
Query: 492 HSSID-EEGYIQGSQR--DRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFK 548
S + + G I S+ + ++ D E K ++ + K +K+ K+ G +
Sbjct: 282 KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATV 341
Query: 549 RHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEIL 608
+ Q+A +K + E+ EE IK +++ ++ E+ E
Sbjct: 342 KAMQEALAKLKEEEERQKREE----------------EERIKRLEELEAKRKEEERLE-- 383
Query: 609 QEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGK 668
QE ++ K+R K G L+ K S E +
Sbjct: 384 QEKRERKKQKEKERKERLKKEG---------------KLLTK----------SQREARAR 418
Query: 669 CLFNRIYLQKKS-EIDSKILERLLEELQKKKK-EEEEARKATEEELRLEEENRRL----- 721
LQ + E+ SK + L KK+ E++ RK ++L +E + +
Sbjct: 419 AEATLKLLQAQGVEVPSK------DSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAA 472
Query: 722 LELMKVKAKEAEET-------DNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEV 774
+E+M+ E EET + ED E+ D+ E E + G+ + E E
Sbjct: 473 VEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKV--HIEVKEN 530
Query: 775 PETEPEAVSEPIE-ETTVETEIPKGSKEGLEIEKLSETV 812
PE E E E E E + E E +G EG E ++ E V
Sbjct: 531 PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Score = 37.7 bits (86), Expect = 0.11
Identities = 84/400 (21%), Positives = 164/400 (41%), Gaps = 39/400 (9%)
Query: 891 EDYEEETEDYQTEAE---VDEEL-----EEEEEEEGEDKMKERKRHLGDTKHFCPVVLKE 942
+D +E E+ EA+ D E E EEE K K++K G + F +E
Sbjct: 56 DDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 943 NFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGS 1002
L+ +++ + K+ +S ++ + F + P+ A + K+ + +
Sbjct: 116 ---LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKK--AKGKAQKSNKKWDGSEEDEDN 170
Query: 1003 GKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKK--VGPEFEEDSENEQAAKQELEELA 1060
K + R + +E LQ + K +K GP E +E++ A+ + ++ +A
Sbjct: 171 SKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFK-IKTVA 229
Query: 1061 IQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIR-ST 1119
+ K E E K+ + +L + +E + + + + + E +K + T
Sbjct: 230 QKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 1120 GFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERK 1179
G I P E+A+ P AA +D + D+ + +K K++K+ E+K
Sbjct: 290 GVI----PASEEKAET-------PTAA-----EDDNEGDKKKKDKKKKKGEKEEKEKEKK 333
Query: 1180 KLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDE 1239
K K + +AK + E ER K+ E ++ EE+ + EE+ + E
Sbjct: 334 KGPSKATVKAMQEALAKLKEEE--ERQKREEEERIKRLEELEAKRKEEERLE----QEKR 387
Query: 1240 FPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQ 1279
K ++E +E ++E + + + E + EA LQ
Sbjct: 388 ERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427
Score = 34.7 bits (78), Expect = 0.92
Identities = 32/118 (27%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Query: 182 ENHRKKKKEAQKDGKGEEEEEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIV 241
E +KKK + +K G+ EE+E+E+++ +A + MQ E L L + E
Sbjct: 310 EGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQ---EALAKLKEEEERQ-------- 358
Query: 242 KLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKRAAILTKLQ 299
K +E ++ LEE+ A+ + +E + ++ +RLK K +LTK Q
Sbjct: 359 KREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLK----KEGKLLTKSQ 412
Score = 32.0 bits (71), Expect = 5.9
Identities = 14/31 (45%), Positives = 23/31 (74%)
Query: 179 EVIENHRKKKKEAQKDGKGEEEEEEEEQEEE 209
EV EN ++++E +++ + EE EEEEE+E E
Sbjct: 526 EVKENPEEEEEEEEEEEEDEESEEEEEEEGE 556
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 65.9 bits (159), Expect = 4e-10
Identities = 43/172 (25%), Positives = 87/172 (50%), Gaps = 8/172 (4%)
Query: 1405 KPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNW 1464
+P+P + I+++G P SGK T + KI YG +++S+G LR +++ ++
Sbjct: 129 RPRPKI---ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 185
Query: 1465 HLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELS 1524
+ G AP E I ++ LM+ + + G+VIDG+P Q E + P ++ L+
Sbjct: 186 IITTGELAPQETTITEIKQKLMQ-IPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLA 244
Query: 1525 VPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQ 1576
++ + +RLL E + R ++ + + +++N + +Y+QE+
Sbjct: 245 CANQRLKERLLKRAEQQGR----PDDNVKATQRRLMNFKQNAAPLVKYFQEK 292
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Query: 1414 IIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMTAP 1473
I I+G P SGK T +K+ +YG HLS G LR L + E+E + ++ + +G P
Sbjct: 379 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS--ESERSKLIRDIMERGDLVP 436
Query: 1474 DELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIFKR 1533
+ ++ L+ +++ S+ +T G +IDGYP Q R P ++ + + + R
Sbjct: 437 SGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNR 496
Query: 1534 LLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQHQ 1578
LL R P+ ++ + +A Y + + YY+ + Q
Sbjct: 497 LL----QRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQ 537
Score = 42.4 bits (98), Expect = 0.004
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 14 DIFDEDETERNFLLSKPVCFVVF--GKPGVGKTTLARYITQAWKCIRVEALPILEEQIAA 71
++F ED T F+ C ++F G PG GK T + + + + +L E++A+
Sbjct: 359 NVFGED-TMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS 417
Query: 72 ETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIP 118
E+E +++ ++ G +P +V++L+ E + + G++I P
Sbjct: 418 ESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYP 464
Score = 40.0 bits (92), Expect = 0.022
Identities = 70/304 (23%), Positives = 116/304 (38%), Gaps = 57/304 (18%)
Query: 985 EPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEE 1044
+P + P I ++G GSGK ++AE+ +I E+L++K+
Sbjct: 126 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKI------------HS 173
Query: 1045 DSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILE 1104
S N K L I +E T +TE IK LM+ +P E
Sbjct: 174 TSSNR---KWSLIAKIITTGELAPQETT--------ITE----IKQKLMQ---IPDE--- 212
Query: 1105 VILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQ 1164
G ++DGFPR +A D+ PD VF+ +Q + +RLL
Sbjct: 213 --------------EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRA 258
Query: 1165 IEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE--LILERDKKRRENVVRDDEEISE 1222
++ + K +++L M K + K E LI+ D R E+ V D ++
Sbjct: 259 EQQGRPDDNVKATQRRL---MNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAV 315
Query: 1223 EELEEDNDDI---ENILEDEFPKDEEEM--SGEEDEEQETDAIERLRGELGEKFEADTHN 1277
+ N + + L+ D E+ +G + E+Q D + + F D
Sbjct: 316 DNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRK 375
Query: 1278 LQII 1281
+II
Sbjct: 376 CKII 379
Score = 35.0 bits (79), Expect = 0.70
Identities = 41/208 (19%), Positives = 77/208 (37%), Gaps = 48/208 (23%)
Query: 994 ICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK 1053
I ++G GSGK +L EK H+ E+L+E+L SE+E++
Sbjct: 379 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELA--------------SESERS-- 422
Query: 1054 QELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLK 1113
++I+ + + +P I+ +L E +
Sbjct: 423 --------------------------------KLIRDIMERGDLVPSGIVLELLKEAMVA 450
Query: 1114 EPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQK 1173
+ GF++DG+PR ++ + G R P + + + +RLL +
Sbjct: 451 SLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDT 510
Query: 1174 KKLERKKLIKDMKAKIRVDTIAKRRAEL 1201
K K+L +A I V + + +L
Sbjct: 511 TKTIAKRLEAYYRASIPVIAYYETKTQL 538
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 65.9 bits (159), Expect = 4e-10
Identities = 43/172 (25%), Positives = 87/172 (50%), Gaps = 8/172 (4%)
Query: 1405 KPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNW 1464
+P+P + I+++G P SGK T + KI YG +++S+G LR +++ ++
Sbjct: 103 RPRPKI---ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 159
Query: 1465 HLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELS 1524
+ G AP E I ++ LM+ + + G+VIDG+P Q E + P ++ L+
Sbjct: 160 IITTGELAPQETTITEIKQKLMQ-IPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLA 218
Query: 1525 VPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQ 1576
++ + +RLL E + R ++ + + +++N + +Y+QE+
Sbjct: 219 CANQRLKERLLKRAEQQGR----PDDNVKATQRRLMNFKQNAAPLVKYFQEK 266
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Query: 1414 IIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMTAP 1473
I I+G P SGK T +K+ +YG HLS G LR L + E+E + ++ + +G P
Sbjct: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS--ESERSKLIRDIMERGDLVP 410
Query: 1474 DELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIFKR 1533
+ ++ L+ +++ S+ +T G +IDGYP Q R P ++ + + + R
Sbjct: 411 SGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNR 470
Query: 1534 LLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQHQ 1578
LL R P+ ++ + +A Y + + YY+ + Q
Sbjct: 471 LL----QRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQ 511
Score = 42.4 bits (98), Expect = 0.004
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 14 DIFDEDETERNFLLSKPVCFVVF--GKPGVGKTTLARYITQAWKCIRVEALPILEEQIAA 71
++F ED T F+ C ++F G PG GK T + + + + +L E++A+
Sbjct: 333 NVFGED-TMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS 391
Query: 72 ETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIP 118
E+E +++ ++ G +P +V++L+ E + + G++I P
Sbjct: 392 ESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYP 438
Score = 40.0 bits (92), Expect = 0.022
Identities = 70/304 (23%), Positives = 116/304 (38%), Gaps = 57/304 (18%)
Query: 985 EPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEE 1044
+P + P I ++G GSGK ++AE+ +I E+L++K+
Sbjct: 100 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKI------------HS 147
Query: 1045 DSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILE 1104
S N K L I +E T +TE IK LM+ +P E
Sbjct: 148 TSSNR---KWSLIAKIITTGELAPQETT--------ITE----IKQKLMQ---IPDE--- 186
Query: 1105 VILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQ 1164
G ++DGFPR +A D+ PD VF+ +Q + +RLL
Sbjct: 187 --------------EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRA 232
Query: 1165 IEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE--LILERDKKRRENVVRDDEEISE 1222
++ + K +++L M K + K E LI+ D R E+ V D ++
Sbjct: 233 EQQGRPDDNVKATQRRL---MNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAV 289
Query: 1223 EELEEDNDDI---ENILEDEFPKDEEEM--SGEEDEEQETDAIERLRGELGEKFEADTHN 1277
+ N + + L+ D E+ +G + E+Q D + + F D
Sbjct: 290 DNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRK 349
Query: 1278 LQII 1281
+II
Sbjct: 350 CKII 353
Score = 35.0 bits (79), Expect = 0.70
Identities = 41/208 (19%), Positives = 77/208 (37%), Gaps = 48/208 (23%)
Query: 994 ICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK 1053
I ++G GSGK +L EK H+ E+L+E+L SE+E++
Sbjct: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELA--------------SESERS-- 396
Query: 1054 QELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLK 1113
++I+ + + +P I+ +L E +
Sbjct: 397 --------------------------------KLIRDIMERGDLVPSGIVLELLKEAMVA 424
Query: 1114 EPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQK 1173
+ GF++DG+PR ++ + G R P + + + +RLL +
Sbjct: 425 SLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDT 484
Query: 1174 KKLERKKLIKDMKAKIRVDTIAKRRAEL 1201
K K+L +A I V + + +L
Sbjct: 485 TKTIAKRLEAYYRASIPVIAYYETKTQL 512
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 65.5 bits (158), Expect = 5e-10
Identities = 68/267 (25%), Positives = 127/267 (47%), Gaps = 21/267 (7%)
Query: 1024 EVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTE 1083
E+ Q + T+KK + E+ E+ A L + N +EE +K +L E
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALS----LELYRNTITDEELKEKN---AKLQE 216
Query: 1084 EEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFP 1143
+ ++++S E E+ L+ LK + +L + EA LG
Sbjct: 217 KLQLVES----------EKSEIQLNVKELKRKLERAKLLLPQ-QQLQAEADHLGKELQSV 265
Query: 1144 DAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELIL 1203
A + QV++ ++++RL Q EK +++K ER++ I++ + KIR RR E ++
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 1204 --ERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDA-I 1260
+ +K RR+ + ++E ELEE + E I E E + EEE E+++ QE +A +
Sbjct: 326 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 385
Query: 1261 ERLRGELGEKFEADTHNLQIIQDELER 1287
R ++ E+ E +++Q++ E+
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEK 412
Score = 63.5 bits (153), Expect = 2e-09
Identities = 116/576 (20%), Positives = 230/576 (39%), Gaps = 116/576 (20%)
Query: 695 QKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEP 754
+ ++K + ++A EL + + R+L K + + A +++EG+ ++
Sbjct: 96 EDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 155
Query: 755 EASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVL 814
S G E +A T+ + IEE T E ++ L +E T+
Sbjct: 156 HDSWKFAG----ELEQALSAVATQKKKADRYIEELTKE-------RDALSLELYRNTITD 204
Query: 815 PEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVV 874
E E + +++ + + + K+L+ + A + + PQ+ LQ
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL---------PQQQLQAEA 255
Query: 875 ETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEE-EEGEDKMKERKRHLGDTK 933
+ + K Q + +L + E E + + + ++ +EE+ +E E+K++E++ + +
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ- 314
Query: 934 HFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLR 993
EE + +E++ + E +EK E EE +
Sbjct: 315 ------------------EEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKI------ 346
Query: 994 ICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK 1053
R+L EK++ QEK+ + EK+ EE+ EQ +
Sbjct: 347 ---------------RELEEKMHE---------QEKIREQEEKRQ----EEEKIREQEKR 378
Query: 1054 QELEELAIQANVKVEEENTKKQLPEVQLTEEEEVI---KSSLMENEPLPPEILEVILSEW 1110
QE E + K+ E+ K + E + E+EE + + + E E E E + +
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ- 437
Query: 1111 WLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKL 1170
+E IR + R EE ++ +Q+ ++ Q EK
Sbjct: 438 --EEKIREQEKKI----REQEE-----------------KIREQE---EMMQEQEEKMGE 471
Query: 1171 KQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENV--VRDDEEISEEELEED 1228
++ K E++ +++ + K+R R+ E I E++KK RE +R+ EE+ +E+ E+
Sbjct: 472 QEGKMCEQEAKMQEQEEKMR------RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 1229 NDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLR 1264
+ E + E E E+E EE+ + RLR
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR 561
Score = 58.5 bits (140), Expect = 6e-08
Identities = 78/334 (23%), Positives = 143/334 (42%), Gaps = 60/334 (17%)
Query: 670 LFNRIYLQKKSEI---DSKILER---LLEELQKKKKEEEEARKATEEELRLEEENRRLLE 723
L+NR+ Q++ ++ + KI ER + E+ +K +++EE+ R+ E EE+ RR E
Sbjct: 278 LWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337
Query: 724 LM---KVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPE 780
+M + K +E EE +E E+ E +E EE + R + + E + E
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 781 AVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFII 840
+ E EE E E G +E E + EM+ +EK+
Sbjct: 398 KIREQ-EEMMQEQEEKMGEQE-----------------EKMWEQEEEMQEQEEKM----- 434
Query: 841 LWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDY 900
++ E I E KI E R +E++Q+ E M E+E +
Sbjct: 435 --RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG---------------EQEGKMC 477
Query: 901 QTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREK 960
+ EA++ E +EE+ E+K++E+++ + + + ++E + E+ + EK
Sbjct: 478 EQEAKMQE--QEEKMRRQEEKIREQEKKIREQEE----KIREQEEMMQEQEEKMWEQEEK 531
Query: 961 IYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRI 994
+ E +EK E E EE ++ +R+
Sbjct: 532 M-----CEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Score = 52.0 bits (123), Expect = 6e-06
Identities = 53/263 (20%), Positives = 122/263 (46%), Gaps = 27/263 (10%)
Query: 1027 QEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEE 1086
QE+ + + E+K+ E+ E E+ +++ E++ Q + E+E ++ E+ +EE+
Sbjct: 286 QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 345
Query: 1087 V--IKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPD 1144
+ ++ + E E + + +E + I + R +EA+ +
Sbjct: 346 IRELEEKMHEQEKIREQ-----------EEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 394
Query: 1145 AAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILE 1204
I+ ++ ++ Q EK +++K E+++ +++ + K+R R+ E I E
Sbjct: 395 QEEKIREQEE-----MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR------RQEEKIRE 443
Query: 1205 RDKKRRENV--VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIER 1262
++KK RE +R+ EE+ +E+ E+ + + E E E+E EE+ + ++
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503
Query: 1263 LRGELGEKFEADTHNLQIIQDEL 1285
+R E EK +Q ++++
Sbjct: 504 IR-EQEEKIREQEEMMQEQEEKM 525
Score = 47.0 bits (110), Expect = 2e-04
Identities = 97/456 (21%), Positives = 181/456 (39%), Gaps = 106/456 (23%)
Query: 636 NCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQ 695
N + ++L + +K I V L K L + LQ +++ K L+ + +LQ
Sbjct: 211 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 270
Query: 696 KKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPE 755
+ +E E + +++ EE+ R E K +E EE E EE+I E ++ + E
Sbjct: 271 AQVEENELWNRLNQQQ---EEKMWRQEE----KIQEREEKIQEQEEKIREQEEKMRRQEE 323
Query: 756 ASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLP 815
+ E+ E E E +EE E E + +E + E+
Sbjct: 324 MMWEKE-----EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE-------- 370
Query: 816 EFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVE 875
+ E E +E+ +W+Q E KI E R +E++Q+ E
Sbjct: 371 --------KIREQEKRQEQEAK---MWRQEE--------KIREQEEKIREQEEMMQEQEE 411
Query: 876 TMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEE---LEEEEEE--EGEDKMKERKRHLG 930
M + + WE E E+E + + E ++ E+ + E+EE+ E E+ M+E++ +G
Sbjct: 412 KMGEQ-EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG 470
Query: 931 DTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAP 990
+ Q G E + K E E EE ++
Sbjct: 471 E---------------QEGKM---------------CEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 991 PLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQ 1050
+I R+ EK+ QE+++ + E+K+ + E+ E E+
Sbjct: 501 EKKI--------------REQEEKIRE---------QEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 1051 AAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEE 1086
+++ E++ + +EE ++Q EV+L ++EE
Sbjct: 538 KMQEQEEKM------RRQEEKMREQ--EVRLRQQEE 565
Score = 44.7 bits (104), Expect = 9e-04
Identities = 94/411 (22%), Positives = 178/411 (43%), Gaps = 40/411 (9%)
Query: 685 KILERLLEELQKKKKE---EEEARKATEEELRLEEENRRLLELMKVKAKEAEETD---NE 738
K +R +EEL K++ E T+EEL+ E+N +L E +++ E E E
Sbjct: 177 KKADRYIEELTKERDALSLELYRNTITDEELK--EKNAKLQEKLQLVESEKSEIQLNVKE 234
Query: 739 DEEEIEGDELEVHEEP-EASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPK 797
+ ++E +L + ++ +A D G L + A + E + + + E +
Sbjct: 235 LKRKLERAKLLLPQQQLQAEADHLGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 293
Query: 798 GSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKIL 857
K EK+ E E+ EM KE+ ++ E + E KI
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE------KMRRQEEMMWEKEEKIR 347
Query: 858 NLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEE 917
LE ++ ++ +K+ E EK + + E+E + ++ E ++ E+ EE+ E
Sbjct: 348 ELE--EKMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ--EEKIRE 401
Query: 918 GEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHP 977
E+ M+E++ +G+ + + E E+ + EKI E ++K E
Sbjct: 402 QEEMMQEQEEKMGEQEE----KMWEQEEEMQEQEEKMRRQEEKI-----REQEKKIREQE 452
Query: 978 EDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQ--LAEKLNIFHIQFEEVL-QEKLLLKT 1034
E EE ++ ++ G Q GK MC ++ + E+ Q E++ QEK + +
Sbjct: 453 EKIREQEEMMQEQEEKM---GEQ-EGK-MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ 507
Query: 1035 EKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEE 1085
E+K+ E EE + ++ E EE + K++E+ K + E ++ E+E
Sbjct: 508 EEKI-REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 40.0 bits (92), Expect = 0.022
Identities = 60/292 (20%), Positives = 132/292 (45%), Gaps = 34/292 (11%)
Query: 1023 EEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELA------IQANVKVEE---ENTK 1073
EE+ +E+ L E +E+ + + A QE +L IQ NVK + E K
Sbjct: 184 EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK 243
Query: 1074 KQLPEVQLTEEEEVIKSSLME-NEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEE 1132
LP+ QL E + + L + L ++ E +E W + + + R E+
Sbjct: 244 LLLPQQQLQAEADHLGKELQSVSAKLQAQVEE---NELWNRLNQQQE----EKMWRQEEK 296
Query: 1133 AQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAK---- 1188
Q ++ + + Q + + ++ + EK + +++ E+++ I++++ K
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 356
Query: 1189 --IRVDTIAKRRAELILERDKK--------RRENVVRDDEE--ISEEELEEDNDDIENIL 1236
IR ++ E I E++K+ R+E +R+ EE +EE+ ++ ++
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ 416
Query: 1237 EDEFPKDEEEMSGEEDE-EQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
E++ + EEEM +E++ ++ + I ++ E+ E +++Q++ E+
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Score = 31.6 bits (70), Expect = 7.8
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
Query: 179 EVIENHRKKKKEAQKDGKGEEE---EEEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLE 235
E I KK +E ++ + +EE E+EE+ E+E + E + + ++R E+ +
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 236 NVENIVKLYKETILQTLEEVMAE 258
E ++ +E I + EE+M E
Sbjct: 499 EQEKKIREQEEKIREQ-EEMMQE 520
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 64.3 bits (155), Expect = 1e-09
Identities = 77/335 (22%), Positives = 132/335 (39%), Gaps = 88/335 (26%)
Query: 991 PLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQ 1050
P++IC++GP GK+ ++LA + HIQ ++V+ E + K E V P + E E
Sbjct: 367 PIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISE-AIAKLEAIVAPNDVGEGEEE- 424
Query: 1051 AAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENE-PLPPEILEVILSE 1109
VEEE ++ + + Q E + IK S+ +N L + + + E
Sbjct: 425 ----------------VEEEEEEENVEDAQ--ELLDGIKESMEQNAGQLDDQYIIRFMKE 466
Query: 1110 WWLKEPIRSTGFILDGFPRYPEEAQ------------------FLGDRGFFPDAAVFIQV 1151
P R+ G+ILDGFP+ ++A+ F D+ P+ +
Sbjct: 467 KLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDA 526
Query: 1152 DDQDIFDRLL--------------------------------------------PAQIEK 1167
D+ + +R++ P I+
Sbjct: 527 SDEFLKERVINLPESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDV 586
Query: 1168 WKLKQ-KKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEELE 1226
KL+ + +L K+LIK++ + +AE E K E + R+ E +E E +
Sbjct: 587 GKLEDAQNRLAIKQLIKEIGEPRNYGLTDEEKAE---EERKAAEERLAREAAEEAEREHQ 643
Query: 1227 EDNDDIENILE-DEFPKDEEEMSGEEDEEQETDAI 1260
E + E I +E+ K EE+ EE E E +I
Sbjct: 644 EAVEMAEKIARWEEWNKRLEEVKREERELLEAQSI 678
Score = 39.3 bits (90), Expect = 0.037
Identities = 62/304 (20%), Positives = 111/304 (36%), Gaps = 77/304 (25%)
Query: 30 PVCFVVFGKPGVGKTTLARYITQAWKCIRVEALPILEEQIA------------------- 70
P+ + G P VGK+++A+ + +K ++ ++ E IA
Sbjct: 367 PIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVE 426
Query: 71 -AETESGV---------MLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIPSL 120
E E V + +SM + + D+ +I+ M EKL S + GYI+ P
Sbjct: 427 EEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKT 486
Query: 121 SQDAMTTLQQIELIKNLNLK-----------PDVIINIKCPDYDLCQRISGQRQHNNTGY 169
A Q + + +++ P+ + + D L +R+ + G
Sbjct: 487 YDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCALDASDEFLKERVINLPESIVAGT 546
Query: 170 IYSRDQW------------DPEVIENHRK------------KKKEAQK--------DGKG 197
YS+D++ D E + N+ K ++AQ G
Sbjct: 547 HYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAIKQLIKEIG 606
Query: 198 EEEE---EEEEQEEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEE 254
E +EE+ EEE AE ++ E + ++ +E E I + E + LEE
Sbjct: 607 EPRNYGLTDEEKAEEERKAAEERLAREAAEEAEREHQEAVEMAEKIARW--EEWNKRLEE 664
Query: 255 VMAE 258
V E
Sbjct: 665 VKRE 668
Score = 38.5 bits (88), Expect = 0.064
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 27/124 (21%)
Query: 1410 VPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVL------------------- 1450
+PI+I I+GPP GK+++AK++ + Y L H+ + + +
Sbjct: 366 MPIKICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEV 425
Query: 1451 ---NNHPETELALMLNWHLHKGM-----TAPDELAIQALELSLMESVCNTAGVVIDGYPV 1502
E A L + + M D+ I+ ++ L C G ++DG+P
Sbjct: 426 EEEEEEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPK 485
Query: 1503 TKHQ 1506
T Q
Sbjct: 486 TYDQ 489
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 63.9 bits (154), Expect = 1e-09
Identities = 102/446 (22%), Positives = 186/446 (41%), Gaps = 55/446 (12%)
Query: 677 QKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETD 736
++K K L +EL++++KE E +K E+E +++E+ ++ E + K +E EE
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWE-QEEKMREQEEKM 333
Query: 737 NEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPE--TEPEAVSEPIEETTVETE 794
EE + E ++ E+ + D ++ E E E E + E E+ E
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER 393
Query: 795 IPKGSKEGLE-----------IEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWK 843
I + K+ E ++K E + E E +PE KEK LW+
Sbjct: 394 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ---KEK------LWE 444
Query: 844 QLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQY--TAWELTGEDYEEETEDYQ 901
Q + E I +I D+ +K + EK + WE + ++E + +
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504
Query: 902 TEA---EVDEELEEEEEE--------EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGN 950
E E DE L E+EE + E+KM+E K+ K +E +
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD--QEEKMREEERM 562
Query: 951 TEEAAKYREKIYYFSSAEAK-----EKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKT 1005
E K RE+ E K EK E E EE ++ ++ +
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM-----WEQEEK 617
Query: 1006 MCGRQLAEKLNIFHIQFEEVL--QEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQA 1063
M ++ +K+ + EE++ QE+ + + E+K+ + E+ E E+ +++ E++ Q
Sbjct: 618 MWEQEEEDKMQ----EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 1064 NVKVEEENTKKQLPEVQLTEEEEVIK 1089
K+ E+ K Q E ++ E+EE ++
Sbjct: 674 E-KMREQEEKMQGQEEKMREQEEKMR 698
Score = 63.5 bits (153), Expect = 2e-09
Identities = 125/609 (20%), Positives = 244/609 (40%), Gaps = 73/609 (11%)
Query: 688 ERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDE 747
E L E +KK +++EE EE LR +E R E K + E+ E E+E+ E
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE---EKMRRQEKRLREQEKELREQE 296
Query: 748 LEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGL---E 804
E+ E+ + E E + + E + E E+ + E +E L E
Sbjct: 297 KELREQKKLR------------EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 805 IEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADR 864
+ + + + E + + +E++ +W+Q E E +I E R
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEE--RIREREKKMR 402
Query: 865 TPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE---EGEDK 921
+E +++ E M+K + WE ++++++ Q E ++E +E+EE E E+K
Sbjct: 403 EEEETMREQEEKMQKQ-EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 922 MKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYV 981
+++++ G K Q EE + +E+ + + +E+ E E
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMW----DQEERMWEQDERLR 517
Query: 982 AHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPE 1041
EE ++ Q K ++ E+ Q E++ +E+ + + EKK+ E
Sbjct: 518 EKEERMREQKKMW-----QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 572
Query: 1042 FEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPE 1101
EE ++ QE EE + K+ E+ K Q E ++ E+EE K E E E
Sbjct: 573 -EEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE--KMWEQEEEDKMQE 629
Query: 1102 ILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLL 1161
E++ W +E E+ Q ++ + + + Q + + +
Sbjct: 630 QEEMM----WEQE----------------EKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 1162 PAQIEKWKLKQKKKLERKKLIKDMKAKIR---------VDTIAKRRAELILERDKKRREN 1212
Q EK + +++K +++ +++ + K+R + + + ++ + + + +E
Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEE 729
Query: 1213 VVRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFE 1272
+RD +E +E L E E E P + + T ++E GE GE
Sbjct: 730 RIRDQKEKMQERLPEHE---ERCSEPCLPPSKVLCN-----MSHTGSVEPAGGEAGEGSP 781
Query: 1273 ADTHNLQII 1281
D Q I
Sbjct: 782 QDNPTAQEI 790
Score = 62.4 bits (150), Expect = 4e-09
Identities = 120/595 (20%), Positives = 258/595 (43%), Gaps = 97/595 (16%)
Query: 692 EELQKKKKEEEEARKATEEE-----LRLEEENRRL----LELMKVKAKEAEETDNEDEEE 742
EEL+KK E +E + E E L ++E R+L L +V+ +E EEE
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 743 IEGDELEVHEEPEASHDTRGSWLPEE---FEASEVPETEPEAVSEPIEETTVETEIPKGS 799
+ E ++ ++ E W EE + ++ E E + + E E+ +
Sbjct: 243 LREQEKKIRKQEEK------MWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQE 296
Query: 800 KEGLEIEKLSE-TVVLPEFPEDSYPDVPEMEPFKEKI-GSFIILWKQLEATISEAYIKIL 857
KE E +KL E + E E + +M +EK+ LW+Q E + E K+
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQ-EKQMREQEQKMR 355
Query: 858 NLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEE-- 915
+ E E L++ E M + Q WE EE+ ++ + E ++++ EEEE
Sbjct: 356 DQEERMWEQDERLREKEERMRE--QEKMWE-----QEEKMQEEERIREREKKMREEEETM 408
Query: 916 EEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLE 975
E E+KM++++ ++ + + + + + +EK++ + +E+ +
Sbjct: 409 REQEEKMQKQEENMWEQEE------------KEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 976 HPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTE 1035
E+ + +E + G K M + EK+ Q E QE+ + E
Sbjct: 457 EQEEKIRDQEEM------------WGQEKKMWRQ---EKMREQEDQMWE--QEEKMRDQE 499
Query: 1036 KKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMEN 1095
+K+ + E E ++ +++ E + Q + +EE ++ E + T+E+E
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEE----KMREEKKTQEQE--------- 546
Query: 1096 EPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQD 1155
W +E +R + + + EE + + ++ + + Q +
Sbjct: 547 -----------KKTWDQEEKMREEERMREREKKMREEEEMMREQ----EEKMQEQEEKMR 591
Query: 1156 IFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVR 1215
+ + Q EK + +++K E+++ + + + + ++ + + E++ E+++K +E +
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM----QEQEEMMWEQEEKMQEQEEK 647
Query: 1216 --DDEEISEEELEEDNDDIENI--LEDEFPKDEEEMSGEEDEEQETDAIERLRGE 1266
+ EE E+ E+ + E + E++ + EE+M G+E++ +E + E++RG+
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE--EKMRGQ 700
Score = 56.6 bits (135), Expect = 2e-07
Identities = 118/608 (19%), Positives = 245/608 (40%), Gaps = 61/608 (10%)
Query: 695 QKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEP 754
+ +KK + ++A E+ ++ R+L K + + A + + E L E
Sbjct: 70 EDEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLG--ESK 127
Query: 755 EASHDTRGSW--LPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETV 812
+ + SW E A T + IEE T E ++ L +E T+
Sbjct: 128 DLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKE-------RDALSLELYRNTI 180
Query: 813 VLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQK 872
E + + +EK+ + E+ SE + + L+ + LL +
Sbjct: 181 TNEELKKKN-------AELQEKL-------RLAESEKSEIQLNVKELKRKLERAKFLLPQ 226
Query: 873 VVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEG-----EDKMKERKR 927
V Q W E E+E + + E ++ + E E+EG E+KM+ +++
Sbjct: 227 V---QTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK 283
Query: 928 HLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPL 987
L + + L+E Q E K RE+ E +EK E E EE +
Sbjct: 284 RLREQEK----ELRE----QEKELREQKKLREQEEQMQ--EQEEKMWEQEEKMREQEEKM 333
Query: 988 KAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSE 1047
R+ Q + R E++ Q E + +++ ++ ++K+ + E+ E
Sbjct: 334 WRQEERLWEQEKQMREQEQKMRDQEERM---WEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 1048 NEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEE-------VIKSSLMENEPLPP 1100
E+ ++E + + ++ +EE +KQ + EE+E K L E E +
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 1101 EILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDR- 1159
+ ++ W +E IR + + + + + ++ +Q ++D+
Sbjct: 451 QEEKI----WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 1160 -LLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKK-RRENVVRDD 1217
+ Q E+ + K+++ E+KK+ + + K+R + + + + ++++K R E +R+
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQ-EEKMREEKKTQEQEKKTWDQEEKMREEERMRER 565
Query: 1218 EEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHN 1277
E+ EE E + E + E E E+E E EE+ + E++ + + +E + +
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 1278 LQIIQDEL 1285
Q+E+
Sbjct: 626 KMQEQEEM 633
Score = 45.1 bits (105), Expect = 7e-04
Identities = 86/405 (21%), Positives = 155/405 (38%), Gaps = 91/405 (22%)
Query: 895 EETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEA 954
EE + E + L E E+ E + +KE KR L K P V + EE
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 955 AKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEK 1014
+ +EK K + E EE L+ + GK R+ EK
Sbjct: 243 LREQEK-----------KIRKQEEKMWRQEERLR-----------EQEGKM---REQEEK 277
Query: 1015 LNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKK 1074
+ + E QEK L + EK++ + + + EQ QE EE + K+ E+ K
Sbjct: 278 MRRQEKRLRE--QEKELREQEKELREQKKLREQEEQM--QEQEEKMWEQEEKMREQEEKM 333
Query: 1075 QLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQ 1134
E +L E+E+ ++ + + D R E+ +
Sbjct: 334 WRQEERLWEQEKQMREQEQK---------------------------MRDQEERMWEQDE 366
Query: 1135 FLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTI 1194
L ++ + + Q + W+ Q++K++ ++ I++ + K+R +
Sbjct: 367 RLREK------------------EERMREQEKMWE--QEEKMQEEERIREREKKMREEEE 406
Query: 1195 AKRRAELILERDKKRRENVVRDDE-EISEEELEEDNDDI----------ENILEDEFP-K 1242
R E E+ +K+ EN+ +E E ++ L E + + E I E E +
Sbjct: 407 TMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463
Query: 1243 DEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
D+EEM G+E + + + ++ E+ E Q + D+ ER
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508
Score = 38.9 bits (89), Expect = 0.049
Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 11/139 (7%)
Query: 176 WDPEVIENHRKKKKEAQKDGKGEEE----EEEEEQEEEEAFIAEMQMVAEILHHLVQRPE 231
WD E ++ +E +K + EEE +EE+ QE+EE + + + E + ++ E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 232 DYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNLKR 291
E E + + +E +Q EE+M E + + EE ++++ K
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM-------QEQEEKMWEQEEKMREQEEKM 662
Query: 292 AAILTKLQGAEEEINDTME 310
K+QG EE++ + E
Sbjct: 663 REQEEKMQGQEEKMREQEE 681
Score = 37.4 bits (85), Expect = 0.14
Identities = 65/336 (19%), Positives = 135/336 (40%), Gaps = 59/336 (17%)
Query: 427 QPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARKQAETALREFQ--RQYEKM--- 481
+ + K E + E E + KEKL + + ++Q E + + R E+M
Sbjct: 412 EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Query: 482 EFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKET 541
E ++ E D+ + RD+ + D EE + + L ++ ++ ++ K
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERM-REQKKMW 530
Query: 542 GETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPY 601
+ + + Q+ K + E + EE E EE + Q+ ++
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQE---EKMREEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 602 EKHAEILQEVLG--EVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKKGIIPDLVIY 659
EK E +++ E M+E +++ W + +++W
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKM--------WEQE-----EKMW--------------- 619
Query: 660 LSDTENNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENR 719
+ E K +Q++ E+ + E++ E+ +K ++EE+ R+ EE++R +EE
Sbjct: 620 --EQEEEDK-------MQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE-QEEKMREQEE-- 667
Query: 720 RLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPE 755
K + EE E EE+++G E ++ E+ E
Sbjct: 668 --------KMQGQEEKMREQEEKMQGQEEKMREQEE 695
Score = 32.3 bits (72), Expect = 4.6
Identities = 31/153 (20%), Positives = 65/153 (42%), Gaps = 3/153 (1%)
Query: 161 QRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ---EEEEAFIAEMQ 217
Q Q T + + + + E +K ++E + + EE+ +E+E+ E+EE + +
Sbjct: 543 QEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEE 602
Query: 218 MVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELF 277
+ E + ++ E E E +E ++ EE M E + + + EE
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 662
Query: 278 MIVMDRLKYLNLKRAAILTKLQGAEEEINDTME 310
++++ K K+QG EE++ + E
Sbjct: 663 REQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 63.2 bits (152), Expect = 2e-09
Identities = 125/627 (19%), Positives = 262/627 (41%), Gaps = 65/627 (10%)
Query: 695 QKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEP 754
+ ++K + ++A EL + R+L K + + A +++EG+ ++
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 755 EASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVET-----EIPKGSKEGLEIE--- 806
S G E +A T+ + IEE T E E+ + + E++
Sbjct: 168 HDSWKFAG----ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223
Query: 807 -KLSETVVLPEFPEDSYP-DVPEMEPFKEKIGSFII----------LWKQLEATISEAYI 854
KL E + L E + +V E++ E+ + L K+L++ ++
Sbjct: 224 AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQA 283
Query: 855 KILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEE 914
++ E+ +R Q+ +K+ EK WE ++ EE+ + + + EE +
Sbjct: 284 QVEENELWNRLNQQQEEKMWRQEEK---IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 915 EE---EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKE 971
EE E E+KM+ ++ + + + + +E + + EE + +E++ + E +E
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEE--KMRRQEEMMWEK---EEKMRRQEEMMW----EKEE 391
Query: 972 KFLE-----HPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVL 1026
K E H ++ + +E + +I + + RQ EK+ + E
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIREQEEKIRE-- 448
Query: 1027 QEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEE-- 1084
QEK + + E+K+ E++ E+ +QE EE+ Q E+E +Q ++ EE
Sbjct: 449 QEKKMWRQEEKI---HEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Query: 1085 ---EEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGF 1141
EE + + +I E W +E IR + + EE +
Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM------WREEEKMHEQEKI 559
Query: 1142 FPDAAVFIQVDDQDIFDRLLPAQIEK-WKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE 1200
+ + Q D + + Q EK W+ ++K + + +K + + + + + + E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 1201 LILERDKKRRENV--VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETD 1258
I E+++K RE +R+ EE+++E+ E+ + E + E E E+E + EE+ +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE 679
Query: 1259 AIERLRGELGEKFEADTHNLQIIQDEL 1285
+++R E EK +Q ++++
Sbjct: 680 QEKKIR-EQEEKIREQEEMMQEQEEKM 705
Score = 61.6 bits (148), Expect = 7e-09
Identities = 93/429 (21%), Positives = 183/429 (42%), Gaps = 52/429 (12%)
Query: 670 LFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELM---- 725
L+NR+ Q++ ++ + E ++E ++K +E+EE + EE++R +EE R E M
Sbjct: 290 LWNRLNQQQEEKMWRQ--EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEK 347
Query: 726 KVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPET--EPEAVS 783
+ K + EE E EE++ E + E+ E +E + E+ E E E +
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 407
Query: 784 EPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWK 843
E E+ E +I E EK E E+ + E +EK +W+
Sbjct: 408 EQEEKRQEEEKIR-------EQEKRQEQEAKMWRQEEKIREQEEKIREQEKK-----MWR 455
Query: 844 QLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTE 903
Q E + I+ E R QE + + E + + Q W + +E+E + + E
Sbjct: 456 QEEKIHEQEKIR----EEEKRQEQEEMWRQEEKIHE--QEEIWRQKEKMHEQEEKIRKQE 509
Query: 904 AEV---DEELEEEEEE--EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYR 958
+V +E++ E+EE+ E E+KM ++ + + EE +
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ-------------------EEMWREE 550
Query: 959 EKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIF 1018
EK++ +EK E + EE ++ ++ + + ++ EK+
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610
Query: 1019 HIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPE 1078
+ E QE+ + + E+K+ + E+ E E+ +++ E++ Q E+E ++ E
Sbjct: 611 EEKIRE--QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 668
Query: 1079 VQLTEEEEV 1087
+EE++
Sbjct: 669 TMWRQEEKI 677
Score = 58.5 bits (140), Expect = 6e-08
Identities = 92/418 (22%), Positives = 173/418 (41%), Gaps = 71/418 (16%)
Query: 677 QKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETD 736
+K E++ K+ E+ Q++K++EEE K E+E R E+E + + K++ E EE
Sbjct: 391 EKIRELEEKMHEQEKIREQEEKRQEEE--KIREQEKRQEQEAKMWRQEEKIR--EQEEKI 446
Query: 737 NEDEEEIEGDELEVHE-----EPEASHDTRGSWLPEE-FEASEVPETEPEAVSEPIEETT 790
E E+++ E ++HE E E + W EE E + E + E E+
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 791 VETEIPKGSKEGL--EIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEAT 848
+ E +E + + EK+ E E+ + EM +EK+ +W+ E
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE--EEK 564
Query: 849 ISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDE 908
E K+ E +K+ E EK ++ E+ +E E+ + E
Sbjct: 565 RQEQEDKMWRQE----------EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKI 614
Query: 909 ELEEEEEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAE 968
+EE+ +E E+K++E++ + +E + E+ + EK+ E
Sbjct: 615 REQEEKIQEQEEKIREQEEKI-----------REQEEMTQEQEEKMGEQEEKM-----CE 658
Query: 969 AKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQE 1028
+EK E E EE ++ +I R+ EK+ QE
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKI--------------REQEEKIRE---------QE 695
Query: 1029 KLLLKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEE 1086
+++ + E+K+ + E+ E E+ +++ E K+ + K EV+L ++EE
Sbjct: 696 EMMQEQEEKMWEQEEKMCEQEEKMQEQEE--------KMRRQEEKMWEQEVRLRQQEE 745
Score = 56.6 bits (135), Expect = 2e-07
Identities = 120/599 (20%), Positives = 253/599 (42%), Gaps = 65/599 (10%)
Query: 685 KILERLLEELQKKKKE---EEEARKATEEELRLEEENRRLLELMKVKAKEAEETD---NE 738
K +R +EEL K++ E T+EEL+ E+N +L E +++ E E E
Sbjct: 189 KKADRYIEELTKERDALSLELYRNTITDEELK--EKNAKLQEKLQLVESEKSEIQLNVKE 246
Query: 739 DEEEIEGDELEVHEEP-EASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPK 797
+ ++E +L + ++ +A D G E ++VS ++ E E+
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGK--------------ELQSVSAKLQAQVEENELWN 292
Query: 798 GSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKIL 857
+ E + + + E+ E ++ +EKI ++ E + E K+
Sbjct: 293 RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR 352
Query: 858 NLEIADRTPQELLQKVVETM-EKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEE 916
E +E +++ E M EK + E + EE+ + + + E++ E+EE+
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 917 -EGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLE 975
+ E+K++E+++ +E E+ + EKI +EK +
Sbjct: 413 RQEEEKIREQEKR------------QEQEAKMWRQEEKIREQEEKI------REQEKKMW 454
Query: 976 HPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTE 1035
E+ + +E ++ R + ++ E+ I+ + + QE+ + K E
Sbjct: 455 RQEEKIHEQEKIREEEKR-----QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQE 509
Query: 1036 KKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMEN 1095
+KV + E+ E E+ +++ E++ Q E+E ++ E ++ E+E++ + +
Sbjct: 510 EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKIWEEEKRQE 567
Query: 1096 EP-----LPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQ 1150
+ +I E W +E IR R +E + + IQ
Sbjct: 568 QEDKMWRQEEKIREQEEKVWRQEEKIRE-----QEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Query: 1151 VDDQDIFDR--LLPAQIEKWKLKQKKKLERKKLIKDMKAKIRV-DTIAKRRAELILERDK 1207
++ I ++ + Q E + +++K E+++ + + + K++ + R+ E I E++K
Sbjct: 623 EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 1208 KRRENV--VRDDEEISEEELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLR 1264
K RE +R+ EE+ +E+ E+ + E + E E E+E EE+ + RLR
Sbjct: 683 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 741
Score = 48.5 bits (114), Expect = 6e-05
Identities = 56/244 (22%), Positives = 104/244 (42%), Gaps = 34/244 (13%)
Query: 683 DSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEE 742
+ KI E+ EE+ +++++ E K EEE R E+E++ + K++ +E + E++
Sbjct: 537 EEKIREQ--EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR 594
Query: 743 IEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEG 802
+ ++ + EE + + E+ + E E E EE T E E G +E
Sbjct: 595 EQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE- 653
Query: 803 LEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIA 862
EK+ E + E++ +W+Q E I E KI E
Sbjct: 654 ---EKMCEQEEKMQEQEET-------------------MWRQ-EEKIREQEKKIREQEEK 690
Query: 863 DRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDKM 922
R +E++Q+ E M WE + E+E + + E ++ + E+ E+E +
Sbjct: 691 IREQEEMMQEQEEKM--------WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQ 742
Query: 923 KERK 926
+E K
Sbjct: 743 QEEK 746
Score = 34.3 bits (77), Expect = 1.2
Identities = 55/300 (18%), Positives = 122/300 (40%), Gaps = 45/300 (15%)
Query: 454 KEKLLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLV 513
+EK+ + + +Q E + E + + K E V+ E +E+ Q + R +
Sbjct: 482 EEKIHEQEEIWRQKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 514 DTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEE 573
+E + E +H+Q K+ +++ ++ E +++ + Q+ K++ + EE
Sbjct: 541 REQEEMWREEEKMHEQE-KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQ-EE 598
Query: 574 VTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWI 633
+ E + EE I+ E+ ++ E ++E ++ E+ + K G
Sbjct: 599 KRQEQEEKMWKQEEKIREQ-----EEKIQEQEEKIREQEEKIREQEEMTQEQEEKMG--- 650
Query: 634 VDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILERLLEE 693
E K +Q++ E + E++ E+
Sbjct: 651 ------------------------------EQEEKMCEQEEKMQEQEETMWRQEEKIREQ 680
Query: 694 LQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEE 753
+K +++EE+ R E+E ++E+ ++ E + K E EE E EE++ E ++ E+
Sbjct: 681 EKKIREQEEKIR---EQEEMMQEQEEKMWE-QEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 736
Score = 32.7 bits (73), Expect = 3.5
Identities = 30/141 (21%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 173 RDQWDPEVIENHRKKKKEAQKDGKGEE---EEEEEEQEEEEAFIAEMQMVAEILHHLVQR 229
R + + ++ K +++ +K + EE E+EE+ QE+EE + + + E + ++
Sbjct: 565 RQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ 624
Query: 230 PEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIELNGNKPAEELFMIVMDRLKYLNL 289
E E E I + +E + Q EE M E + + + EE ++++
Sbjct: 625 EEKIREQEEKIRE--QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Query: 290 KRAAILTKLQGAEEEINDTME 310
K K++ EE + + E
Sbjct: 683 KIREQEEKIREQEEMMQEQEE 703
Score = 32.7 bits (73), Expect = 3.5
Identities = 21/80 (26%), Positives = 44/80 (55%), Gaps = 4/80 (5%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEET 735
++++ E+ + E++ E+ +K ++EE+ ++ E R EE+ R + K +E EE
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIRE----QEKKIREQEEK 690
Query: 736 DNEDEEEIEGDELEVHEEPE 755
E EE ++ E ++ E+ E
Sbjct: 691 IREQEEMMQEQEEKMWEQEE 710
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 62.0 bits (149), Expect = 5e-09
Identities = 197/918 (21%), Positives = 348/918 (37%), Gaps = 184/918 (20%)
Query: 421 DYAQLVQPRFDKA---RETLVENTIAEATAAAIKVVKEKLLR---ELQARKQAETALREF 474
DYA+LV +K ++ V+ AE A +KV ++ R E+Q+ + TA E
Sbjct: 454 DYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA 513
Query: 475 QRQYEKMEFGVFPME--ATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENVLHDQAAK 532
+Q + +F E + HS + + + R L+++E+ + E L Q
Sbjct: 514 AQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQD 573
Query: 533 VDKDDGKETGETFTFKRHSQDASQDV------KLYSDTAPTEDLI---EEVTADHPEVVT 583
+ + + + F HSQ A+Q +L+ A + I E+ A + +T
Sbjct: 574 ILEQNEALKAQIQQF--HSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLT 631
Query: 584 MIEETIKMSQDINF--EQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVK 641
EE +K Q++NF + +K + E E K + VK
Sbjct: 632 SKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEK-------------MQQSVYVK 678
Query: 642 ELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKILE-RLLEELQKKKKE 700
+ + L+++ Q + EI +K+ E ++L + K K
Sbjct: 679 DDKIRLLEE--------------------------QLQHEISNKMEEFKILNDQNKALKS 712
Query: 701 EEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEEEIEGDELEV--HEEPEASH 758
E + + L E+ N+ ++E M+ +E +E EE +E ++V EE +
Sbjct: 713 EVQKLQT----LVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAI 768
Query: 759 DTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFP 818
T S L +E + + + + + + +EE G + +E E L ++
Sbjct: 769 RTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVE-ELLEAELLKVANK 827
Query: 819 EDSYPDVP-EMEPFKEKIGSFIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETM 877
E + D+ E++ KE+IG+ + L K + +I+ ++ NL ++ V+E
Sbjct: 828 EKTVQDLKQEIKALKEEIGN-VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEK 886
Query: 878 EKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDKMKERKRHLGDTKHFCP 937
EK T L +D +EE E + A V E + +E E
Sbjct: 887 EKDLANTGKWL--QDLQEENESLK--AHVQEVAQHNLKEASSASQFEELE---------- 932
Query: 938 VVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAPPLRICLV 997
+VLKE KE L+ E + E
Sbjct: 933 IVLKE---------------------------KENELKRLEAMLKERES----------- 954
Query: 998 GPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEE----DSENEQAAK 1053
S KT + + ++ +F Q E++ Q+ + P EE SE E+
Sbjct: 955 --DLSSKTQLLQDVQDENKLFKSQIEQLKQQNY---QQASSFPPHEELLKVISEREKEIS 1009
Query: 1054 ---QELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEW 1110
EL+ L + ++ N ++Q E E +EV+K L +P + EW
Sbjct: 1010 GLWNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKK-LFPKVSVPSNLS---YGEW 1065
Query: 1111 WLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKL 1170
L GF + +E G G + ++ + D LL + EK+K
Sbjct: 1066 ------------LHGFEKKAKECM-AGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKS 1112
Query: 1171 KQKK------KLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENVVRDDEEISEEE 1224
+ KL+R ++ K K++VD K K+ + + ++E+ E
Sbjct: 1113 VLAETEGILQKLQRSVEQEENKWKVKVDESHKTI--------KQMQSSFTSSEQEL--ER 1162
Query: 1225 LEEDNDDIENI------LEDEFPKDEEEMSGEEDEEQE-----TDAIERLRGELGE--KF 1271
L +N DIEN+ LE E K E E S E +E + + +LR E E K
Sbjct: 1163 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKV 1222
Query: 1272 EADTH----NLQIIQDEL 1285
D H +L++IQ ++
Sbjct: 1223 AGDLHKAQQSLELIQSKI 1240
Score = 38.5 bits (88), Expect = 0.064
Identities = 134/688 (19%), Positives = 284/688 (41%), Gaps = 97/688 (14%)
Query: 649 KKGIIPDLVIYLSDT-ENNGKCLFNRI---YLQKKSEIDSKILERLLEELQKKKKEEEEA 704
+ GI+ D V ++ E+ N++ Y + +E+ K + EE+QKK E+
Sbjct: 425 ENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQA-- 482
Query: 705 RKATEEELRLEEENRRLLEL---MKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTR 761
AT+ +++L+E RR E+ ++ + E E + + + E EV DT
Sbjct: 483 --ATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTL 540
Query: 762 GSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDS 821
S E ++ E+E + V++ +E L+++ + + E +
Sbjct: 541 VSKQQLEQRLMQLMESEQKRVNK---------------EESLQMQ-------VQDILEQN 578
Query: 822 YPDVPEMEPFKEKIG---SFIILWKQLEATISEAYIKILNLEIA-----DR-TPQELLQK 872
+++ F +I S +L ++L I+E +I E + DR T +E K
Sbjct: 579 EALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELK 638
Query: 873 VVETMEKPFQYTAWELTGEDYEE-----ETEDYQTEAEVDEE----LEEEEEEEGEDKMK 923
++ M + +L E+ E E Q V ++ LEE+ + E +KM+
Sbjct: 639 DIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKME 698
Query: 924 ERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAK--EKFLEHPEDYV 981
E K K V K ++ ++ + EK + K E+ LE V
Sbjct: 699 EFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQV 758
Query: 982 A-HEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGP 1040
A EE L A + + S T + L K N + F +++E + EK
Sbjct: 759 ATKEEELNA-------IRTENSSLTKEVQDLKAKQN-DQVSFASLVEELKKVIHEKDGKI 810
Query: 1041 EFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSS-------LM 1093
+ E+ + K +E +Q ++K E + K+++ VQL + +++ +S L+
Sbjct: 811 KSVEELLEAELLKVANKEKTVQ-DLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLL 869
Query: 1094 ENEPLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDD 1153
+ + ++ +L E ++ + +TG L E + A +V
Sbjct: 870 KGKEEQMNTMKAVLEE--KEKDLANTGKWLQDLQEENESLK-----------AHVQEVAQ 916
Query: 1154 QDIFDRLLPAQIEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAELILERDKKRRENV 1213
++ + +Q E+ ++ K+K K ++ M + D +K + ++ + K ++
Sbjct: 917 HNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQ 976
Query: 1214 VRDDEEISEEELEE-----DNDDIENILEDEFPKDEEEMSGEEDE-EQETDAIERLRGEL 1267
+ E++ ++ ++ ++++ ++ + E+E+SG +E + DA+E R +
Sbjct: 977 I---EQLKQQNYQQASSFPPHEELLKVISER----EKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 1268 GEKFEADTHNLQIIQDELERYLIPIISI 1295
E+ + +++ E+ + L P +S+
Sbjct: 1030 NER-QQQVEAVELEAKEVLKKLFPKVSV 1056
Score = 35.0 bits (79), Expect = 0.70
Identities = 84/438 (19%), Positives = 159/438 (36%), Gaps = 47/438 (10%)
Query: 406 TLCNMLAENYKGKVVDYAQLVQPRFDKARETLVENTIAEATAAAIKVVKEKLLRELQARK 465
T ++LAE + + + ++ D T E I+ + L E+Q +
Sbjct: 596 TSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQ 655
Query: 466 QAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGSSLVDTEEAKTKSENV 525
+ EKM+ V+ + ++E+ + S + +++ + KSE
Sbjct: 656 ALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSE-- 713
Query: 526 LHDQAAKVDKDDGKETGETFTFKRHSQDASQDVKLYSDTAPTEDLIEEVTADHP--EVVT 583
+ V + K+ E ++ Q+ + +K + T LI+ T + + T
Sbjct: 714 VQKLQTLVSEQPNKDVVEQM--EKCIQEKDEKLKTVEELLET-GLIQVATKEEELNAIRT 770
Query: 584 MIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGAPKYGGWIVDNCPIVKEL 643
K QD+ +Q + L E L +V+ E + + + EL
Sbjct: 771 ENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEEL---------LEAEL 821
Query: 644 WMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSE--IDSKILERLLEELQKKKKEE 701
K+ + DL + + + L+K + I SK+ E L+ L K K+E+
Sbjct: 822 LKVANKEKTVQDLKQEIKALKEE----IGNVQLEKAQQLSITSKVQE--LQNLLKGKEEQ 875
Query: 702 EEARKATEEELRLEEENRRLLELMKVKAKEAEETDN--EDEEEIEGDELEVHEEPEASHD 759
KA EE K K+ T +D +E E + L+ H + A H+
Sbjct: 876 MNTMKAVLEE----------------KEKDLANTGKWLQDLQE-ENESLKAHVQEVAQHN 918
Query: 760 TRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVV----LP 815
+ + +FE E+ E E + +E E E SK L + E + +
Sbjct: 919 LKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIE 978
Query: 816 EFPEDSYPDVPEMEPFKE 833
+ + +Y P +E
Sbjct: 979 QLKQQNYQQASSFPPHEE 996
Score = 32.3 bits (72), Expect = 4.6
Identities = 36/193 (18%), Positives = 76/193 (39%), Gaps = 9/193 (4%)
Query: 94 VIKLMLEKLNSPEVCHFGYIITEIPSLSQDAMTTLQQIELIKNLNLK------PDVIINI 147
V+K + K++ P +G + +++ M E +K L K ++ +
Sbjct: 1046 VLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQL 1105
Query: 148 KCPDY-DLCQRISGQRQHNNTGYIYSRDQWDPEVIENHRKKKKEAQKDGKGEEEEEEEEQ 206
+C Y + G Q ++W +V E+H+ K+ E+E E
Sbjct: 1106 ECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRS 1165
Query: 207 EEEEAFIAEMQMVAEILHHLVQRPEDYLENVENIVKLYKETILQTLEEVMAEHNPQYLIE 266
E ++ I ++ E L +++ E V+ K + +TL ++ E N + +
Sbjct: 1166 ENKD--IENLRREREHLEMELEKAEMERSTYVTEVRELKAQLNETLTKLRTEQNERQKVA 1223
Query: 267 LNGNKPAEELFMI 279
+ +K + L +I
Sbjct: 1224 GDLHKAQQSLELI 1236
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 61.6 bits (148), Expect = 7e-09
Identities = 149/646 (23%), Positives = 267/646 (41%), Gaps = 92/646 (14%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKV----KAKE 731
LQK E K E L+EL++K + E + +E+L+ E E E M+V K +E
Sbjct: 861 LQKTKERQQKA-ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 919
Query: 732 AEETDNE-----DEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPI 786
EE +E +EEE G +L+ + A L E+ E E + + +
Sbjct: 920 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD---LEEQLEEEEAARQKLQ-----L 971
Query: 787 EETTVETEIPKGSKEGLEIE----KLS-ETVVLPEFPEDSYPDVPEMEPFKEKIGSFIIL 841
E+ T E +I K E L ++ KLS E +L E D ++ E E EK + L
Sbjct: 972 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKL 1028
Query: 842 WKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQ 901
+ E+ ISE ++ L E R E L++ +E F +L + E + + +
Sbjct: 1029 KNKHESMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1087
Query: 902 TEAEVDEELEEEEEEEGE-----DKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAK 956
E E+ L ++E + K++E + H+ D L+E+ + +A K
Sbjct: 1088 KEEELQAALARLDDEIAQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEK 1139
Query: 957 YREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAP-PLRICLVGPQGSGKTMCGRQLAEKL 1015
+ + EA + LE D A ++ L+A + ++ +T +++
Sbjct: 1140 QKRDL--GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1197
Query: 1016 NIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELE--------ELAIQANVKV 1067
H Q E L E+L +F+ N KQ LE EL + K
Sbjct: 1198 RQKHAQAVEELTEQL---------EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 1068 EEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFP 1127
E E+ KK+L E Q+ E ++S + E E+ + + L+ + S +L+
Sbjct: 1249 EVEHKKKKL-EAQVQE----LQSKCSDGERARAELNDKVHK---LQNEVESVTGMLN--- 1297
Query: 1128 RYPEEAQFLGDRGFFPDAAVFIQVDD-----QDIFDRLLPAQIEKWKLKQKKKLERKKLI 1182
EA+ + A++ Q+ D Q+ + L + +L++++ + +L
Sbjct: 1298 ----EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 1183 KDMKAKIRVDT-IAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFP 1241
++M+AK ++ I+ +L D K++ E EE + +IEN+ +
Sbjct: 1354 EEMEAKQNLERHISTLNIQL---SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ---- 1406
Query: 1242 KDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
EE + D+ ++T RL+ EL + D N + + LE+
Sbjct: 1407 -QYEEKAAAYDKLEKTK--NRLQQEL-DDLVVDLDNQRQLVSNLEK 1448
Score = 44.3 bits (103), Expect = 0.001
Identities = 122/570 (21%), Positives = 211/570 (37%), Gaps = 89/570 (15%)
Query: 409 NMLAENYKGKVVDYAQLVQP------RFDKARETLVENTIAEATAAAIKVVKEK------ 456
N+ + K K+ D+A V+ RF K E L + E AA K+ K K
Sbjct: 1370 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ-YEEKAAAYDKLEKTKNRLQQE 1428
Query: 457 ---LLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGS--- 510
L+ +L ++Q + L + QR+++++ + + ++ DE + R++ +
Sbjct: 1429 LDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA--DERDRAEAEAREKETKAL 1486
Query: 511 ----SLVDTEEAKTKSENVLHDQAAKVD-----KDD-GKETGETFTFKRHSQDASQDVK- 559
+L + EAK + E A+++ KDD GK E KR + +++K
Sbjct: 1487 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1546
Query: 560 ----LYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEV 615
L + TED + + + E ++ + N E+ + + L E E+
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ-LHEYETEL 1605
Query: 616 MEENKDRFPGAP---KYGGWI------VDNCPIVKELWMALIKK--GIIPDLVIYLSDTE 664
+E K R A K G + D+ +E + ++K + D L D
Sbjct: 1606 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1665
Query: 665 NNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATE-------EELRLEEE 717
+ +F K++E +K LE L +LQ+ E ARK + EEL
Sbjct: 1666 ASRDEIFATA---KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 1722
Query: 718 NRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPET 777
R L+ K + EA E+E E E +E + + L E
Sbjct: 1723 GRNALQDEK-RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1781
Query: 778 EPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGS 837
+ E+ + +E E EG K T+ E KI
Sbjct: 1782 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE----------------AKIAQ 1825
Query: 838 FIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEET 897
L +Q+E E +L+ D+ +E+L +V + + E Y+E+
Sbjct: 1826 ---LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK----------MAEQYKEQA 1872
Query: 898 EDYQTEA-EVDEELEEEEEEEGEDKMKERK 926
E ++ +LEE EEE RK
Sbjct: 1873 EKGNARVKQLKRQLEEAEEESQRINANRRK 1902
Score = 40.8 bits (94), Expect = 0.013
Identities = 153/811 (18%), Positives = 320/811 (39%), Gaps = 122/811 (15%)
Query: 512 LVDTEEAKTKSENVLHDQAAK-----VDKDDGKETGETFTFKRHSQDASQDVKLYSDTAP 566
L T+E + K+EN L + K +K+ +E + T + +++ V+L +
Sbjct: 861 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQE 919
Query: 567 TEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGA 626
E+++ E+ A +EE Q + E+ +K A+ + ++ ++ EE R
Sbjct: 920 LEEILHEMEA-------RLEEEEDRGQQLQAER--KKMAQQMLDLEEQLEEEEAAR---- 966
Query: 627 PKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKI 686
+ K A IKK + D ++ + D N K + K+
Sbjct: 967 --------QKLQLEKVTAEAKIKK--LEDEILVMDDQNN-------------KLSKERKL 1003
Query: 687 LERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEE---EI 743
LE + +L EEEE K +L+ ++ ++ ++V+ K+ E++ E E+ ++
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLT---KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1060
Query: 744 EGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGL 803
EGD + HE+ D + + + ++ E A++ ++ EI + +
Sbjct: 1061 EGDASDFHEQ---IADLQAQIAELKMQLAKKEEELQAALAR------LDDEIAQKNNALK 1111
Query: 804 EIEKLSETVV-LPEFPEDSYPDVPEMEPFKEKIGSFI-ILWKQLEATISEAYIKILNLEI 861
+I +L + L E + + E K +G + L +LE T+
Sbjct: 1112 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD----------- 1160
Query: 862 ADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDK 921
+ T QEL K + + + + +EET ++ + + + + EE ++
Sbjct: 1161 STATQQELRAKREQEV---------TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 922 MKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYV 981
+++ KR + K L+ N + A + R E K+K LE
Sbjct: 1212 LEQFKRAKANLD-------KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE------ 1258
Query: 982 AHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVL-----QEKLLLKTEK 1036
A + L++ C G + +L +K++ + E V E +K K
Sbjct: 1259 AQVQELQSK----CSDGERARA------ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
Query: 1037 KVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENE 1096
V ++ Q QE + + K+ + ++ + QL EE E ++
Sbjct: 1309 DVA-SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1367
Query: 1097 PLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVD---- 1152
L ++ + S+ L++ + + +G R+ +E + L + + AA + +++
Sbjct: 1368 TLNIQLSD---SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ-YEEKAAAYDKLEKTKN 1423
Query: 1153 --DQDIFDRLLPAQIEKWKLKQKKKLERK--KLIKDMKAKIRVDTIAKRRAELILERDKK 1208
Q++ D ++ ++ + +K +RK +L+ + K + RAE +
Sbjct: 1424 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1483
Query: 1209 RRENVVRDDEEISE--EELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE 1266
+ ++ R EE E EELE N ++ +ED ++ + E+ A+E E
Sbjct: 1484 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543
Query: 1267 LGEKFEADTHNLQIIQDELERYLIPIISING 1297
+ + E LQ +D R + + ++ G
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKG 1574
Score = 39.3 bits (90), Expect = 0.037
Identities = 154/731 (21%), Positives = 274/731 (37%), Gaps = 131/731 (17%)
Query: 455 EKLLRELQARKQAETALREFQRQYEKME---------FGVFPMEATHSSIDEEGYIQGSQ 505
E+L +L+ K+A+ L + ++ EK G E H E +Q Q
Sbjct: 1206 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1265
Query: 506 RDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDV-KLYSDT 564
S D E A+ + L+D+ K+ + TG + + ++DV L S
Sbjct: 1266 ----SKCSDGERARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1317
Query: 565 APTEDLIEEVTADHPEVVTMIEETIK--------MSQDINFEQPYEKHAEILQEVLG--- 613
T++L++E T V T + + + + +++ +Q E+H L L
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377
Query: 614 ----------EVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKK---------GIIP 654
E +EE K RF ++N E A K +
Sbjct: 1378 KKLQDFASTVEALEEGKKRFQKE-------IENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 655 DLVIYLSDTENNGKCLFNRIYLQKKSE--------IDSKI-------------------- 686
DLV+ D +N + + N Q+K + I SK
Sbjct: 1431 DLVV---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1487
Query: 687 LERLLEELQKKKKEEEEARKATEEELR-----LEEENRRLLELMKVKAKEAEETDNEDE- 740
L R LEE + K+E E K + E+ ++ + + EL K+K A ET E+
Sbjct: 1488 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL--EKSKRALETQMEEMK 1545
Query: 741 ---EEIEGDELEVHEEPEASHDTRGSWLPEEFEAS-EVPETEPEAVSEPIE------ETT 790
EE+E DEL+ E+ + + L +FE + + + E ++ ET
Sbjct: 1546 TQLEELE-DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1604
Query: 791 VETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATIS 850
+E E + + +KL + E DS ++ +E I KQL +
Sbjct: 1605 LEDERKQRALAAAAKKKLEGDLKDLELQADS-----AIKGREEAI-------KQLRKLQA 1652
Query: 851 EAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVD-EE 909
+ LE A + E+ E +K A + ++ E + +A+++ EE
Sbjct: 1653 QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Query: 910 LEEE--EEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSA 967
L EE G + +++ KR L L+E ++ K ++ S+
Sbjct: 1713 LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 968 EAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLA---EKLNIFHIQFEE 1024
A E+ + + + LR L +G+ K+ +A K+ Q E+
Sbjct: 1773 LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ 1832
Query: 1025 VLQEKLL----LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ 1080
+EK LK + K E E+E+ ++ +E A + N +V++ K+QL E +
Sbjct: 1833 EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ--LKRQLEEAE 1890
Query: 1081 LTEEEEVIKSS 1091
EE + I ++
Sbjct: 1891 --EESQRINAN 1899
Score = 33.9 bits (76), Expect = 1.6
Identities = 55/249 (22%), Positives = 107/249 (42%), Gaps = 20/249 (8%)
Query: 1047 ENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVI 1106
E E AK++ + + K E E + + QLTEE+ +++ L L E E+
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910
Query: 1107 LSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRL--LPAQ 1164
+ K+ + IL EE + G + +Q + + + ++ L Q
Sbjct: 911 VRLAAKKQELEE---ILHEMEARLEEEEDRGQQ---------LQAERKKMAQQMLDLEEQ 958
Query: 1165 IEKWKLKQKKKLERKKLIKDMK-AKIRVDTIAKRRAELILERDKKRRENVVRD-DEEISE 1222
+E+ + ++KL+ +K+ + K K+ + + L +++K E + D ++E
Sbjct: 959 LEE-EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1017
Query: 1223 EELEEDN-DDIENILEDEFPKDEEEMSGEEDEEQETDAIER-LRGELGEKFEADTHNLQI 1280
EE + N ++N E + E + EE QE + ++R L G+ + F +LQ
Sbjct: 1018 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIADLQA 1076
Query: 1281 IQDELERYL 1289
EL+ L
Sbjct: 1077 QIAELKMQL 1085
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 61.6 bits (148), Expect = 7e-09
Identities = 149/646 (23%), Positives = 267/646 (41%), Gaps = 92/646 (14%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKV----KAKE 731
LQK E K E L+EL++K + E + +E+L+ E E E M+V K +E
Sbjct: 868 LQKTKERQQKA-ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 732 AEETDNE-----DEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPI 786
EE +E +EEE G +L+ + A L E+ E E + + +
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD---LEEQLEEEEAARQKLQ-----L 978
Query: 787 EETTVETEIPKGSKEGLEIE----KLS-ETVVLPEFPEDSYPDVPEMEPFKEKIGSFIIL 841
E+ T E +I K E L ++ KLS E +L E D ++ E E EK + L
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKL 1035
Query: 842 WKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQ 901
+ E+ ISE ++ L E R E L++ +E F +L + E + + +
Sbjct: 1036 KNKHESMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 902 TEAEVDEELEEEEEEEGE-----DKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAK 956
E E+ L ++E + K++E + H+ D L+E+ + +A K
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEK 1146
Query: 957 YREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAP-PLRICLVGPQGSGKTMCGRQLAEKL 1015
+ + EA + LE D A ++ L+A + ++ +T +++
Sbjct: 1147 QKRDL--GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204
Query: 1016 NIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELE--------ELAIQANVKV 1067
H Q E L E+L +F+ N KQ LE EL + K
Sbjct: 1205 RQKHAQAVEELTEQL---------EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 1068 EEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFP 1127
E E+ KK+L E Q+ E ++S + E E+ + + L+ + S +L+
Sbjct: 1256 EVEHKKKKL-EAQVQE----LQSKCSDGERARAELNDKVHK---LQNEVESVTGMLN--- 1304
Query: 1128 RYPEEAQFLGDRGFFPDAAVFIQVDD-----QDIFDRLLPAQIEKWKLKQKKKLERKKLI 1182
EA+ + A++ Q+ D Q+ + L + +L++++ + +L
Sbjct: 1305 ----EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 1183 KDMKAKIRVDT-IAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFP 1241
++M+AK ++ I+ +L D K++ E EE + +IEN+ +
Sbjct: 1361 EEMEAKQNLERHISTLNIQL---SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ---- 1413
Query: 1242 KDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
EE + D+ ++T RL+ EL + D N + + LE+
Sbjct: 1414 -QYEEKAAAYDKLEKTK--NRLQQEL-DDLVVDLDNQRQLVSNLEK 1455
Score = 44.3 bits (103), Expect = 0.001
Identities = 122/570 (21%), Positives = 211/570 (37%), Gaps = 89/570 (15%)
Query: 409 NMLAENYKGKVVDYAQLVQP------RFDKARETLVENTIAEATAAAIKVVKEK------ 456
N+ + K K+ D+A V+ RF K E L + E AA K+ K K
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ-YEEKAAAYDKLEKTKNRLQQE 1435
Query: 457 ---LLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGS--- 510
L+ +L ++Q + L + QR+++++ + + ++ DE + R++ +
Sbjct: 1436 LDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA--DERDRAEAEAREKETKAL 1493
Query: 511 ----SLVDTEEAKTKSENVLHDQAAKVD-----KDD-GKETGETFTFKRHSQDASQDVK- 559
+L + EAK + E A+++ KDD GK E KR + +++K
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1553
Query: 560 ----LYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEV 615
L + TED + + + E ++ + N E+ + + L E E+
Sbjct: 1554 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ-LHEYETEL 1612
Query: 616 MEENKDRFPGAP---KYGGWI------VDNCPIVKELWMALIKK--GIIPDLVIYLSDTE 664
+E K R A K G + D+ +E + ++K + D L D
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 665 NNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATE-------EELRLEEE 717
+ +F K++E +K LE L +LQ+ E ARK + EEL
Sbjct: 1673 ASRDEIFATA---KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 1729
Query: 718 NRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPET 777
R L+ K + EA E+E E E +E + + L E
Sbjct: 1730 GRNALQDEK-RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1788
Query: 778 EPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGS 837
+ E+ + +E E EG K T+ E KI
Sbjct: 1789 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE----------------AKIAQ 1832
Query: 838 FIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEET 897
L +Q+E E +L+ D+ +E+L +V + + E Y+E+
Sbjct: 1833 ---LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK----------MAEQYKEQA 1879
Query: 898 EDYQTEA-EVDEELEEEEEEEGEDKMKERK 926
E ++ +LEE EEE RK
Sbjct: 1880 EKGNARVKQLKRQLEEAEEESQRINANRRK 1909
Score = 40.8 bits (94), Expect = 0.013
Identities = 153/811 (18%), Positives = 320/811 (39%), Gaps = 122/811 (15%)
Query: 512 LVDTEEAKTKSENVLHDQAAK-----VDKDDGKETGETFTFKRHSQDASQDVKLYSDTAP 566
L T+E + K+EN L + K +K+ +E + T + +++ V+L +
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQE 926
Query: 567 TEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGA 626
E+++ E+ A +EE Q + E+ +K A+ + ++ ++ EE R
Sbjct: 927 LEEILHEMEA-------RLEEEEDRGQQLQAER--KKMAQQMLDLEEQLEEEEAAR---- 973
Query: 627 PKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKI 686
+ K A IKK + D ++ + D N K + K+
Sbjct: 974 --------QKLQLEKVTAEAKIKK--LEDEILVMDDQNN-------------KLSKERKL 1010
Query: 687 LERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEE---EI 743
LE + +L EEEE K +L+ ++ ++ ++V+ K+ E++ E E+ ++
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLT---KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1067
Query: 744 EGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGL 803
EGD + HE+ D + + + ++ E A++ ++ EI + +
Sbjct: 1068 EGDASDFHEQ---IADLQAQIAELKMQLAKKEEELQAALAR------LDDEIAQKNNALK 1118
Query: 804 EIEKLSETVV-LPEFPEDSYPDVPEMEPFKEKIGSFI-ILWKQLEATISEAYIKILNLEI 861
+I +L + L E + + E K +G + L +LE T+
Sbjct: 1119 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD----------- 1167
Query: 862 ADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDK 921
+ T QEL K + + + + +EET ++ + + + + EE ++
Sbjct: 1168 STATQQELRAKREQEV---------TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 922 MKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYV 981
+++ KR + K L+ N + A + R E K+K LE
Sbjct: 1219 LEQFKRAKANLD-------KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE------ 1265
Query: 982 AHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVL-----QEKLLLKTEK 1036
A + L++ C G + +L +K++ + E V E +K K
Sbjct: 1266 AQVQELQSK----CSDGERARA------ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315
Query: 1037 KVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENE 1096
V ++ Q QE + + K+ + ++ + QL EE E ++
Sbjct: 1316 DVA-SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1374
Query: 1097 PLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVD---- 1152
L ++ + S+ L++ + + +G R+ +E + L + + AA + +++
Sbjct: 1375 TLNIQLSD---SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ-YEEKAAAYDKLEKTKN 1430
Query: 1153 --DQDIFDRLLPAQIEKWKLKQKKKLERK--KLIKDMKAKIRVDTIAKRRAELILERDKK 1208
Q++ D ++ ++ + +K +RK +L+ + K + RAE +
Sbjct: 1431 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1490
Query: 1209 RRENVVRDDEEISE--EELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE 1266
+ ++ R EE E EELE N ++ +ED ++ + E+ A+E E
Sbjct: 1491 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550
Query: 1267 LGEKFEADTHNLQIIQDELERYLIPIISING 1297
+ + E LQ +D R + + ++ G
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Score = 39.3 bits (90), Expect = 0.037
Identities = 154/731 (21%), Positives = 274/731 (37%), Gaps = 131/731 (17%)
Query: 455 EKLLRELQARKQAETALREFQRQYEKME---------FGVFPMEATHSSIDEEGYIQGSQ 505
E+L +L+ K+A+ L + ++ EK G E H E +Q Q
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 506 RDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDV-KLYSDT 564
S D E A+ + L+D+ K+ + TG + + ++DV L S
Sbjct: 1273 ----SKCSDGERARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1324
Query: 565 APTEDLIEEVTADHPEVVTMIEETIK--------MSQDINFEQPYEKHAEILQEVLG--- 613
T++L++E T V T + + + + +++ +Q E+H L L
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384
Query: 614 ----------EVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKK---------GIIP 654
E +EE K RF ++N E A K +
Sbjct: 1385 KKLQDFASTVEALEEGKKRFQKE-------IENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 655 DLVIYLSDTENNGKCLFNRIYLQKKSE--------IDSKI-------------------- 686
DLV+ D +N + + N Q+K + I SK
Sbjct: 1438 DLVV---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1494
Query: 687 LERLLEELQKKKKEEEEARKATEEELR-----LEEENRRLLELMKVKAKEAEETDNEDE- 740
L R LEE + K+E E K + E+ ++ + + EL K+K A ET E+
Sbjct: 1495 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL--EKSKRALETQMEEMK 1552
Query: 741 ---EEIEGDELEVHEEPEASHDTRGSWLPEEFEAS-EVPETEPEAVSEPIE------ETT 790
EE+E DEL+ E+ + + L +FE + + + E ++ ET
Sbjct: 1553 TQLEELE-DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1611
Query: 791 VETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATIS 850
+E E + + +KL + E DS ++ +E I KQL +
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADS-----AIKGREEAI-------KQLRKLQA 1659
Query: 851 EAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVD-EE 909
+ LE A + E+ E +K A + ++ E + +A+++ EE
Sbjct: 1660 QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Query: 910 LEEE--EEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSA 967
L EE G + +++ KR L L+E ++ K ++ S+
Sbjct: 1720 LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 968 EAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLA---EKLNIFHIQFEE 1024
A E+ + + + LR L +G+ K+ +A K+ Q E+
Sbjct: 1780 LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ 1839
Query: 1025 VLQEKLL----LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ 1080
+EK LK + K E E+E+ ++ +E A + N +V++ K+QL E +
Sbjct: 1840 EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ--LKRQLEEAE 1897
Query: 1081 LTEEEEVIKSS 1091
EE + I ++
Sbjct: 1898 --EESQRINAN 1906
Score = 33.9 bits (76), Expect = 1.6
Identities = 55/249 (22%), Positives = 107/249 (42%), Gaps = 20/249 (8%)
Query: 1047 ENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVI 1106
E E AK++ + + K E E + + QLTEE+ +++ L L E E+
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 1107 LSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRL--LPAQ 1164
+ K+ + IL EE + G + +Q + + + ++ L Q
Sbjct: 918 VRLAAKKQELEE---ILHEMEARLEEEEDRGQQ---------LQAERKKMAQQMLDLEEQ 965
Query: 1165 IEKWKLKQKKKLERKKLIKDMK-AKIRVDTIAKRRAELILERDKKRRENVVRD-DEEISE 1222
+E+ + ++KL+ +K+ + K K+ + + L +++K E + D ++E
Sbjct: 966 LEE-EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1024
Query: 1223 EELEEDN-DDIENILEDEFPKDEEEMSGEEDEEQETDAIER-LRGELGEKFEADTHNLQI 1280
EE + N ++N E + E + EE QE + ++R L G+ + F +LQ
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIADLQA 1083
Query: 1281 IQDELERYL 1289
EL+ L
Sbjct: 1084 QIAELKMQL 1092
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 61.6 bits (148), Expect = 7e-09
Identities = 149/646 (23%), Positives = 267/646 (41%), Gaps = 92/646 (14%)
Query: 676 LQKKSEIDSKILERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKV----KAKE 731
LQK E K E L+EL++K + E + +E+L+ E E E M+V K +E
Sbjct: 868 LQKTKERQQKA-ENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQE 926
Query: 732 AEETDNE-----DEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPI 786
EE +E +EEE G +L+ + A L E+ E E + + +
Sbjct: 927 LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD---LEEQLEEEEAARQKLQ-----L 978
Query: 787 EETTVETEIPKGSKEGLEIE----KLS-ETVVLPEFPEDSYPDVPEMEPFKEKIGSFIIL 841
E+ T E +I K E L ++ KLS E +L E D ++ E E EK + L
Sbjct: 979 EKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKL 1035
Query: 842 WKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQ 901
+ E+ ISE ++ L E R E L++ +E F +L + E + + +
Sbjct: 1036 KNKHESMISELEVR-LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAK 1094
Query: 902 TEAEVDEELEEEEEEEGE-----DKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAK 956
E E+ L ++E + K++E + H+ D L+E+ + +A K
Sbjct: 1095 KEEELQAALARLDDEIAQKNNALKKIRELEGHISD--------LQEDLDSERAARNKAEK 1146
Query: 957 YREKIYYFSSAEAKEKFLEHPEDYVAHEEPLKAP-PLRICLVGPQGSGKTMCGRQLAEKL 1015
+ + EA + LE D A ++ L+A + ++ +T +++
Sbjct: 1147 QKRDL--GEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEM 1204
Query: 1016 NIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAKQELE--------ELAIQANVKV 1067
H Q E L E+L +F+ N KQ LE EL + K
Sbjct: 1205 RQKHAQAVEELTEQL---------EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 1068 EEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLKEPIRSTGFILDGFP 1127
E E+ KK+L E Q+ E ++S + E E+ + + L+ + S +L+
Sbjct: 1256 EVEHKKKKL-EAQVQE----LQSKCSDGERARAELNDKVHK---LQNEVESVTGMLN--- 1304
Query: 1128 RYPEEAQFLGDRGFFPDAAVFIQVDD-----QDIFDRLLPAQIEKWKLKQKKKLERKKLI 1182
EA+ + A++ Q+ D Q+ + L + +L++++ + +L
Sbjct: 1305 ----EAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 1183 KDMKAKIRVDT-IAKRRAELILERDKKRRENVVRDDEEISEEELEEDNDDIENILEDEFP 1241
++M+AK ++ I+ +L D K++ E EE + +IEN+ +
Sbjct: 1361 EEMEAKQNLERHISTLNIQL---SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ---- 1413
Query: 1242 KDEEEMSGEEDEEQETDAIERLRGELGEKFEADTHNLQIIQDELER 1287
EE + D+ ++T RL+ EL + D N + + LE+
Sbjct: 1414 -QYEEKAAAYDKLEKTK--NRLQQEL-DDLVVDLDNQRQLVSNLEK 1455
Score = 44.3 bits (103), Expect = 0.001
Identities = 122/570 (21%), Positives = 211/570 (37%), Gaps = 89/570 (15%)
Query: 409 NMLAENYKGKVVDYAQLVQP------RFDKARETLVENTIAEATAAAIKVVKEK------ 456
N+ + K K+ D+A V+ RF K E L + E AA K+ K K
Sbjct: 1377 NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ-YEEKAAAYDKLEKTKNRLQQE 1435
Query: 457 ---LLRELQARKQAETALREFQRQYEKMEFGVFPMEATHSSIDEEGYIQGSQRDRGS--- 510
L+ +L ++Q + L + QR+++++ + + ++ DE + R++ +
Sbjct: 1436 LDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYA--DERDRAEAEAREKETKAL 1493
Query: 511 ----SLVDTEEAKTKSENVLHDQAAKVD-----KDD-GKETGETFTFKRHSQDASQDVK- 559
+L + EAK + E A+++ KDD GK E KR + +++K
Sbjct: 1494 SLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKT 1553
Query: 560 ----LYSDTAPTEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEV 615
L + TED + + + E ++ + N E+ + + L E E+
Sbjct: 1554 QLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ-LHEYETEL 1612
Query: 616 MEENKDRFPGAP---KYGGWI------VDNCPIVKELWMALIKK--GIIPDLVIYLSDTE 664
+E K R A K G + D+ +E + ++K + D L D
Sbjct: 1613 EDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDAR 1672
Query: 665 NNGKCLFNRIYLQKKSEIDSKILERLLEELQKKKKEEEEARKATE-------EELRLEEE 717
+ +F K++E +K LE L +LQ+ E ARK + EEL
Sbjct: 1673 ASRDEIFATA---KENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLS 1729
Query: 718 NRRLLELMKVKAKEAEETDNEDEEEIEGDELEVHEEPEASHDTRGSWLPEEFEASEVPET 777
R L+ K + EA E+E E E +E + + L E
Sbjct: 1730 GRNALQDEK-RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQ 1788
Query: 778 EPEAVSEPIEETTVETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGS 837
+ E+ + +E E EG K T+ E KI
Sbjct: 1789 KNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE----------------AKIAQ 1832
Query: 838 FIILWKQLEATISEAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEET 897
L +Q+E E +L+ D+ +E+L +V + + E Y+E+
Sbjct: 1833 ---LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK----------MAEQYKEQA 1879
Query: 898 EDYQTEA-EVDEELEEEEEEEGEDKMKERK 926
E ++ +LEE EEE RK
Sbjct: 1880 EKGNARVKQLKRQLEEAEEESQRINANRRK 1909
Score = 40.8 bits (94), Expect = 0.013
Identities = 153/811 (18%), Positives = 320/811 (39%), Gaps = 122/811 (15%)
Query: 512 LVDTEEAKTKSENVLHDQAAK-----VDKDDGKETGETFTFKRHSQDASQDVKLYSDTAP 566
L T+E + K+EN L + K +K+ +E + T + +++ V+L +
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAET-ELYAEAEEMRVRLAAKKQE 926
Query: 567 TEDLIEEVTADHPEVVTMIEETIKMSQDINFEQPYEKHAEILQEVLGEVMEENKDRFPGA 626
E+++ E+ A +EE Q + E+ +K A+ + ++ ++ EE R
Sbjct: 927 LEEILHEMEA-------RLEEEEDRGQQLQAER--KKMAQQMLDLEEQLEEEEAAR---- 973
Query: 627 PKYGGWIVDNCPIVKELWMALIKKGIIPDLVIYLSDTENNGKCLFNRIYLQKKSEIDSKI 686
+ K A IKK + D ++ + D N K + K+
Sbjct: 974 --------QKLQLEKVTAEAKIKK--LEDEILVMDDQNN-------------KLSKERKL 1010
Query: 687 LERLLEELQKKKKEEEEARKATEEELRLEEENRRLLELMKVKAKEAEETDNEDEE---EI 743
LE + +L EEEE K +L+ ++ ++ ++V+ K+ E++ E E+ ++
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLT---KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL 1067
Query: 744 EGDELEVHEEPEASHDTRGSWLPEEFEASEVPETEPEAVSEPIEETTVETEIPKGSKEGL 803
EGD + HE+ D + + + ++ E A++ ++ EI + +
Sbjct: 1068 EGDASDFHEQ---IADLQAQIAELKMQLAKKEEELQAALAR------LDDEIAQKNNALK 1118
Query: 804 EIEKLSETVV-LPEFPEDSYPDVPEMEPFKEKIGSFI-ILWKQLEATISEAYIKILNLEI 861
+I +L + L E + + E K +G + L +LE T+
Sbjct: 1119 KIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD----------- 1167
Query: 862 ADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVDEELEEEEEEEGEDK 921
+ T QEL K + + + + +EET ++ + + + + EE ++
Sbjct: 1168 STATQQELRAKREQEV---------TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 922 MKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSAEAKEKFLEHPEDYV 981
+++ KR + K L+ N + A + R E K+K LE
Sbjct: 1219 LEQFKRAKANLD-------KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE------ 1265
Query: 982 AHEEPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVL-----QEKLLLKTEK 1036
A + L++ C G + +L +K++ + E V E +K K
Sbjct: 1266 AQVQELQSK----CSDGERARA------ELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315
Query: 1037 KVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENE 1096
V ++ Q QE + + K+ + ++ + QL EE E ++
Sbjct: 1316 DVA-SLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIS 1374
Query: 1097 PLPPEILEVILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVD---- 1152
L ++ + S+ L++ + + +G R+ +E + L + + AA + +++
Sbjct: 1375 TLNIQLSD---SKKKLQDFASTVEALEEGKKRFQKEIENLTQQ-YEEKAAAYDKLEKTKN 1430
Query: 1153 --DQDIFDRLLPAQIEKWKLKQKKKLERK--KLIKDMKAKIRVDTIAKRRAELILERDKK 1208
Q++ D ++ ++ + +K +RK +L+ + K + RAE +
Sbjct: 1431 RLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKET 1490
Query: 1209 RRENVVRDDEEISE--EELEEDNDDIENILEDEFPKDEEEMSGEEDEEQETDAIERLRGE 1266
+ ++ R EE E EELE N ++ +ED ++ + E+ A+E E
Sbjct: 1491 KALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550
Query: 1267 LGEKFEADTHNLQIIQDELERYLIPIISING 1297
+ + E LQ +D R + + ++ G
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKG 1581
Score = 39.3 bits (90), Expect = 0.037
Identities = 154/731 (21%), Positives = 274/731 (37%), Gaps = 131/731 (17%)
Query: 455 EKLLRELQARKQAETALREFQRQYEKME---------FGVFPMEATHSSIDEEGYIQGSQ 505
E+L +L+ K+A+ L + ++ EK G E H E +Q Q
Sbjct: 1213 EELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQ 1272
Query: 506 RDRGSSLVDTEEAKTKSENVLHDQAAKVDKDDGKETGETFTFKRHSQDASQDV-KLYSDT 564
S D E A+ + L+D+ K+ + TG + + ++DV L S
Sbjct: 1273 ----SKCSDGERARAE----LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQL 1324
Query: 565 APTEDLIEEVTADHPEVVTMIEETIK--------MSQDINFEQPYEKHAEILQEVLG--- 613
T++L++E T V T + + + + +++ +Q E+H L L
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384
Query: 614 ----------EVMEENKDRFPGAPKYGGWIVDNCPIVKELWMALIKK---------GIIP 654
E +EE K RF ++N E A K +
Sbjct: 1385 KKLQDFASTVEALEEGKKRFQKE-------IENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 655 DLVIYLSDTENNGKCLFNRIYLQKKSE--------IDSKI-------------------- 686
DLV+ D +N + + N Q+K + I SK
Sbjct: 1438 DLVV---DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALS 1494
Query: 687 LERLLEELQKKKKEEEEARKATEEELR-----LEEENRRLLELMKVKAKEAEETDNEDE- 740
L R LEE + K+E E K + E+ ++ + + EL K+K A ET E+
Sbjct: 1495 LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHEL--EKSKRALETQMEEMK 1552
Query: 741 ---EEIEGDELEVHEEPEASHDTRGSWLPEEFEAS-EVPETEPEAVSEPIE------ETT 790
EE+E DEL+ E+ + + L +FE + + + E ++ ET
Sbjct: 1553 TQLEELE-DELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETE 1611
Query: 791 VETEIPKGSKEGLEIEKLSETVVLPEFPEDSYPDVPEMEPFKEKIGSFIILWKQLEATIS 850
+E E + + +KL + E DS ++ +E I KQL +
Sbjct: 1612 LEDERKQRALAAAAKKKLEGDLKDLELQADS-----AIKGREEAI-------KQLRKLQA 1659
Query: 851 EAYIKILNLEIADRTPQELLQKVVETMEKPFQYTAWELTGEDYEEETEDYQTEAEVD-EE 909
+ LE A + E+ E +K A + ++ E + +A+++ EE
Sbjct: 1660 QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Query: 910 LEEE--EEEEGEDKMKERKRHLGDTKHFCPVVLKENFILQPGNTEEAAKYREKIYYFSSA 967
L EE G + +++ KR L L+E ++ K ++ S+
Sbjct: 1720 LAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 968 EAKEKFLEHPEDYVAHEEPLKAPPLRICLVGPQGSGKTMCGRQLA---EKLNIFHIQFEE 1024
A E+ + + + LR L +G+ K+ +A K+ Q E+
Sbjct: 1780 LATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQ 1839
Query: 1025 VLQEKLL----LKTEKKVGPEFEEDSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQ 1080
+EK LK + K E E+E+ ++ +E A + N +V++ K+QL E +
Sbjct: 1840 EAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQ--LKRQLEEAE 1897
Query: 1081 LTEEEEVIKSS 1091
EE + I ++
Sbjct: 1898 --EESQRINAN 1906
Score = 33.9 bits (76), Expect = 1.6
Identities = 55/249 (22%), Positives = 107/249 (42%), Gaps = 20/249 (8%)
Query: 1047 ENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVI 1106
E E AK++ + + K E E + + QLTEE+ +++ L L E E+
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917
Query: 1107 LSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRL--LPAQ 1164
+ K+ + IL EE + G + +Q + + + ++ L Q
Sbjct: 918 VRLAAKKQELEE---ILHEMEARLEEEEDRGQQ---------LQAERKKMAQQMLDLEEQ 965
Query: 1165 IEKWKLKQKKKLERKKLIKDMK-AKIRVDTIAKRRAELILERDKKRRENVVRD-DEEISE 1222
+E+ + ++KL+ +K+ + K K+ + + L +++K E + D ++E
Sbjct: 966 LEE-EEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAE 1024
Query: 1223 EELEEDN-DDIENILEDEFPKDEEEMSGEEDEEQETDAIER-LRGELGEKFEADTHNLQI 1280
EE + N ++N E + E + EE QE + ++R L G+ + F +LQ
Sbjct: 1025 EEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASD-FHEQIADLQA 1083
Query: 1281 IQDELERYL 1289
EL+ L
Sbjct: 1084 QIAELKMQL 1092
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,658,228
Number of Sequences: 37866
Number of extensions: 3961998
Number of successful extensions: 63936
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 441
Number of HSP's successfully gapped in prelim test: 888
Number of HSP's that attempted gapping in prelim test: 26516
Number of HSP's gapped (non-prelim): 24901
length of query: 1911
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1794
effective length of database: 13,817,196
effective search space: 24788049624
effective search space used: 24788049624
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.