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Search of human proteins with 237649113
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237649113 Rho-related BTB domain containing 2 isoform 3
[Homo sapiens]
(727 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo... 1498 0.0
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo... 1498 0.0
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo... 1498 0.0
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] 973 0.0
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra... 130 3e-30
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil... 130 4e-30
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi... 126 6e-29
gi|46249393 ras homolog gene family, member G [Homo sapiens] 125 1e-28
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] 121 2e-27
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] 121 2e-27
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] 121 2e-27
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra... 120 4e-27
gi|10835049 ras homolog gene family, member A [Homo sapiens] 119 1e-26
gi|50263042 ras-like protein TC10 [Homo sapiens] 114 3e-25
gi|7656900 ras homolog D [Homo sapiens] 110 4e-24
gi|111494251 ras homolog gene family, member C precursor [Homo s... 110 5e-24
gi|111494248 ras homolog gene family, member C precursor [Homo s... 110 5e-24
gi|28395033 ras homolog gene family, member C precursor [Homo sa... 110 5e-24
gi|11034843 ras homolog gene family, member U [Homo sapiens] 105 1e-22
gi|4757764 ras homolog gene family, member B [Homo sapiens] 103 4e-22
gi|16903164 ras homolog gene family, member J [Homo sapiens] 103 7e-22
gi|229577148 ras homolog gene family, member V [Homo sapiens] 102 2e-21
gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] 100 5e-21
gi|4885581 Rho family GTPase 2 [Homo sapiens] 92 1e-18
gi|7657514 GTP-binding protein RHO6 [Homo sapiens] 89 2e-17
gi|4885069 ras homolog gene family, member E [Homo sapiens] 84 4e-16
gi|4757770 ras homolog gene family, member H [Homo sapiens] 84 5e-16
gi|38016957 ras homolog gene family, member F [Homo sapiens] 84 6e-16
gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens] 55 2e-07
gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens] 55 2e-07
>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
sapiens]
Length = 727
Score = 1498 bits (3877), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60
MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR
Sbjct: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60
Query: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120
VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT
Sbjct: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120
Query: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180
MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE
Sbjct: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180
Query: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240
LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP
Sbjct: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240
Query: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300
PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL
Sbjct: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300
Query: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 360
SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA
Sbjct: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 360
Query: 361 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 420
GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS
Sbjct: 361 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 420
Query: 421 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 480
IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK
Sbjct: 421 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 480
Query: 481 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 540
AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE
Sbjct: 481 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 540
Query: 541 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 600
VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME
Sbjct: 541 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 600
Query: 601 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 660
ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY
Sbjct: 601 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 660
Query: 661 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 720
FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP
Sbjct: 661 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 720
Query: 721 SSSSAVV 727
SSSSAVV
Sbjct: 721 SSSSAVV 727
>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
sapiens]
Length = 734
Score = 1498 bits (3877), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60
MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR
Sbjct: 8 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 67
Query: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120
VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT
Sbjct: 68 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 127
Query: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180
MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE
Sbjct: 128 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 187
Query: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240
LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP
Sbjct: 188 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 247
Query: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300
PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL
Sbjct: 248 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 307
Query: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 360
SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA
Sbjct: 308 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 367
Query: 361 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 420
GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS
Sbjct: 368 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 427
Query: 421 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 480
IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK
Sbjct: 428 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 487
Query: 481 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 540
AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE
Sbjct: 488 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 547
Query: 541 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 600
VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME
Sbjct: 548 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 607
Query: 601 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 660
ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY
Sbjct: 608 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 667
Query: 661 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 720
FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP
Sbjct: 668 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 727
Query: 721 SSSSAVV 727
SSSSAVV
Sbjct: 728 SSSSAVV 734
>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
sapiens]
Length = 749
Score = 1498 bits (3877), Expect = 0.0
Identities = 727/727 (100%), Positives = 727/727 (100%)
Query: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60
MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR
Sbjct: 23 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 82
Query: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120
VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT
Sbjct: 83 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 142
Query: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180
MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE
Sbjct: 143 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 202
Query: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240
LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP
Sbjct: 203 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 262
Query: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300
PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL
Sbjct: 263 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 322
Query: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 360
SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA
Sbjct: 323 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 382
Query: 361 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 420
GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS
Sbjct: 383 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 442
Query: 421 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 480
IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK
Sbjct: 443 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 502
Query: 481 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 540
AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE
Sbjct: 503 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 562
Query: 541 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 600
VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME
Sbjct: 563 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 622
Query: 601 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 660
ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY
Sbjct: 623 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 682
Query: 661 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 720
FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP
Sbjct: 683 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 742
Query: 721 SSSSAVV 727
SSSSAVV
Sbjct: 743 SSSSAVV 749
>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
Length = 696
Score = 973 bits (2516), Expect = 0.0
Identities = 483/710 (68%), Positives = 563/710 (79%), Gaps = 23/710 (3%)
Query: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60
MD+DMDYERPNVETIKCVVVGDNAVGKTRLICARACN TLTQYQLLATHVPTVWAIDQYR
Sbjct: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60
Query: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120
VCQEVLERSRDVVD+VSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSL+HVK+
Sbjct: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120
Query: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180
MWYPEIKHFCPR PVILVGCQLDLRYADLEAVNRARRPLARPIK +ILPPEKGREVAKE
Sbjct: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180
Query: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240
LG+PYYETSV QFGIKDVFDNAIRAALISRRHLQFWKSHL+ VQ+PLLQAPFLPPK PP
Sbjct: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240
Query: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300
P+I +P+ PS A LL++PLCADV+ +LQ++ IFAH+IYL+TSSSKFYDLFLM+
Sbjct: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300
Query: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- 359
E P +G ++ RDF R S D E +E P
Sbjct: 301 EES------------PNGSEGACEK------EKQSRDFQGRILSVDPEEEREEGPPRIPQ 342
Query: 360 AGLRASTSDGILRGNG---TGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK 416
A S++ ++ G G +P + L+ WS+ F+ + EM +P++ + M VV+
Sbjct: 343 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 401
Query: 417 MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ 476
MD+S+QPGPFR +L++LYTG+LDE E+DL+ +A IAE+LE+FDLRMMV NI+N EAFMNQ
Sbjct: 402 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 461
Query: 477 EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES 536
EITKAFHVR+ NR+KECL+KGTFSDVTF LDDG ISAHKPLLI SC+WMAAMFGG FVES
Sbjct: 462 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 521
Query: 537 STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT 596
+ EV P +K M+AVL+YLYT + + DLD ++LI LANR CLPHLVAL EQ+ V
Sbjct: 522 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 581
Query: 597 GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE 656
L +A V IDG+VL +LELAQFH A+QLA WCLHHICTNYN+VC KF +++K+ S +
Sbjct: 582 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 641
Query: 657 NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNS 706
NQEYFE+HRWPPVWYLKEEDHYQR ++EREKED K + +R+W FWNS
Sbjct: 642 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS 691
>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
[Homo sapiens]
Length = 192
Score = 130 bits (328), Expect = 3e-30
Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y +
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
Query: 72 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
+VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V+ WYPE++H
Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYET 188
CP P+ILVG +LDLR D + + + + PI +G +AKE+G + Y E
Sbjct: 105 CPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------TYPQGLAMAKEIGAVKYLEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K VFD AIRA L
Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177
>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
small GTP binding protein Rac3) [Homo sapiens]
Length = 192
Score = 130 bits (327), Expect = 4e-30
Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y +
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
Query: 72 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
+VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V+ WYPE++H
Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYET 188
CP P++LVG +LDLR D + + R R PI +G +A+E+G + Y E
Sbjct: 105 CPHTPILLVGTKLDLR-DDKDTIERLRDKKLAPI------TYPQGLAMAREIGSVKYLEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K VFD AIRA L
Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177
>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
sapiens]
Length = 192
Score = 126 bits (317), Expect = 6e-29
Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y +
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
Query: 72 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
+VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V+ W+PE++H
Sbjct: 45 MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188
CP P+ILVG +LDLR D + + + + PI +G +AKE+ + Y E
Sbjct: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPI------TYPQGLALAKEIDSVKYLEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K VFD AIRA L
Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177
>gi|46249393 ras homolog gene family, member G [Homo sapiens]
Length = 191
Score = 125 bits (314), Expect = 1e-28
Identities = 77/200 (38%), Positives = 115/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
+++IKCVVVGD AVGKT L+ NA +Y +PTV+ D Y ++
Sbjct: 1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44
Query: 72 VVDDVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
VD +V+L LWDT G DR +Y +++V V+CFSIA+P S +V+ W+PE+ H
Sbjct: 45 AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188
CP P++LVG + DLR A + + R + PI P++G+ +AK++ + Y E
Sbjct: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K+VF A+RA L
Sbjct: 158 SALQQDGVKEVFAEAVRAVL 177
>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
Length = 191
Score = 121 bits (304), Expect = 2e-27
Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V
Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44
Query: 72 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H
Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188
CP+ P +LVG Q+DLR D + + + +PI PE ++A++L + Y E
Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K+VFD AI AAL
Sbjct: 158 SALTQRGLKNVFDEAILAAL 177
>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 121 bits (304), Expect = 2e-27
Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V
Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44
Query: 72 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H
Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188
CP+ P +LVG Q+DLR D + + + +PI PE ++A++L + Y E
Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K+VFD AI AAL
Sbjct: 158 SALTQKGLKNVFDEAILAAL 177
>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
Length = 191
Score = 121 bits (304), Expect = 2e-27
Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V
Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44
Query: 72 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H
Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 188
CP+ P +LVG Q+DLR D + + + +PI PE ++A++L + Y E
Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157
Query: 189 SVVAQFGIKDVFDNAIRAAL 208
S + Q G+K+VFD AI AAL
Sbjct: 158 SALTQKGLKNVFDEAILAAL 177
>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
[Homo sapiens]
Length = 211
Score = 120 bits (301), Expect = 4e-27
Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y +
Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44
Query: 72 VVDDVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 110
+VD V+L LWDT G DR YG+ +DV ++CFS+
Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104
Query: 111 NPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILP 170
+P S +V+ WYPE++H CP P+ILVG +LDLR D + + + + PI
Sbjct: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------T 157
Query: 171 PEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAAL 208
+G +AKE+G + Y E S + Q G+K VFD AIRA L
Sbjct: 158 YPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196
>gi|10835049 ras homolog gene family, member A [Homo sapiens]
Length = 193
Score = 119 bits (298), Expect = 1e-26
Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 26/200 (13%)
Query: 16 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75
K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D
Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50
Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133
V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP
Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVA 192
P+ILVG + DLR + RR LA+ E + PE+GR++A +G Y E S
Sbjct: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163
Query: 193 QFGIKDVFDNAIRAALISRR 212
+ G+++VF+ A RAAL +RR
Sbjct: 164 KDGVREVFEMATRAALQARR 183
>gi|50263042 ras-like protein TC10 [Homo sapiens]
Length = 205
Score = 114 bits (285), Expect = 3e-25
Identities = 79/207 (38%), Positives = 111/207 (53%), Gaps = 26/207 (12%)
Query: 10 PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69
P +KCVVVGD AVGKT L+ + A +A +Y VPTV+ D Y V
Sbjct: 5 PGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVSV------ 50
Query: 70 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 127
V L L+DT G D+ + R +Y +DV ++CFS+ NP S +VK W PE+K
Sbjct: 51 --TVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELK 108
Query: 128 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYY 186
+ P P +L+G Q+DLR D + + R +PI E+G+++AKE+G Y
Sbjct: 109 EYAPNVPFLLIGTQIDLR-DDPKTLARLNDMKEKPI------CVEQGQKLAKEIGACCYV 161
Query: 187 ETSVVAQFGIKDVFDNAIRAALISRRH 213
E S + Q G+K VFD AI A L ++H
Sbjct: 162 ECSALTQKGLKTVFDEAIIAILTPKKH 188
>gi|7656900 ras homolog D [Homo sapiens]
Length = 210
Score = 110 bits (276), Expect = 4e-24
Identities = 73/212 (34%), Positives = 108/212 (50%), Gaps = 27/212 (12%)
Query: 10 PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69
P V ++K V+VGD GKT L+ A A Y PTV+ ++Y V +V +
Sbjct: 13 PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESY------TPTVF--ERYMVNLQVKGKP 64
Query: 70 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 127
V L +WDT G D+ + R Y + V++LCF + +PNS ++ WYPE+
Sbjct: 65 --------VHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVN 116
Query: 128 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYY 186
HFC + P+I+VGC+ DLR D VN+ RR P+ + +G+E+A+ +G + Y
Sbjct: 117 HFCKKVPIIVVGCKTDLR-KDKSLVNKLRRNGLEPVTYH------RGQEMARSVGAVAYL 169
Query: 187 ETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 218
E S + VF A AL SR FW+
Sbjct: 170 ECSARLHDNVHAVFQEAAEVALSSRGR-NFWR 200
>gi|111494251 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 110 bits (275), Expect = 5e-24
Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%)
Query: 16 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75
K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D
Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50
Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133
V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP
Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 192
P+ILVG + DLR + RR LA+ E + E+GR++A + Y E S
Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163
Query: 193 QFGIKDVFDNAIRAALISRRH 213
+ G+++VF+ A RA L R++
Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184
>gi|111494248 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 110 bits (275), Expect = 5e-24
Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%)
Query: 16 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75
K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D
Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50
Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133
V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP
Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 192
P+ILVG + DLR + RR LA+ E + E+GR++A + Y E S
Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163
Query: 193 QFGIKDVFDNAIRAALISRRH 213
+ G+++VF+ A RA L R++
Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184
>gi|28395033 ras homolog gene family, member C precursor [Homo
sapiens]
Length = 193
Score = 110 bits (275), Expect = 5e-24
Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%)
Query: 16 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75
K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D
Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50
Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133
V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP
Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 192
P+ILVG + DLR + RR LA+ E + E+GR++A + Y E S
Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163
Query: 193 QFGIKDVFDNAIRAALISRRH 213
+ G+++VF+ A RA L R++
Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184
>gi|11034843 ras homolog gene family, member U [Homo sapiens]
Length = 258
Score = 105 bits (263), Expect = 1e-22
Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 26/197 (13%)
Query: 15 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74
+KCV+VGD AVGKT L+ + N T+Y +PT A D + V D
Sbjct: 50 VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93
Query: 75 DVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 132
V L+L DT G D R Y +D+ +LCFS+ +P+S +V W PEI+ CP+
Sbjct: 94 GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153
Query: 133 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVV 191
AP+ILVG Q DLR D++ + + +P+ P E + A+E+ Y E S +
Sbjct: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206
Query: 192 AQFGIKDVFDNAIRAAL 208
Q +K+VFD AI A +
Sbjct: 207 TQKNLKEVFDAAIVAGI 223
>gi|4757764 ras homolog gene family, member B [Homo sapiens]
Length = 196
Score = 103 bits (258), Expect = 4e-22
Identities = 72/199 (36%), Positives = 104/199 (52%), Gaps = 26/199 (13%)
Query: 16 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75
K VVVGD A GKT L+ ++ + +VPTV+ + Y EV D
Sbjct: 7 KLVVVGDGACGKTCLLIV------FSKDEFPEVYVPTVF--ENYVADIEV--------DG 50
Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133
V L LWDT G D+ + R +Y +DV+++CFS+ +P+SL ++ W PE+KHFCP
Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNV 110
Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 192
P+ILV + DLR + R LAR E + + GR +A + Y E S
Sbjct: 111 PIILVANKKDLR-----SDEHVRTELAR--MKQEPVRTDDGRAMAVRIQAYDYLECSAKT 163
Query: 193 QFGIKDVFDNAIRAALISR 211
+ G+++VF+ A RAAL R
Sbjct: 164 KEGVREVFETATRAALQKR 182
>gi|16903164 ras homolog gene family, member J [Homo sapiens]
Length = 214
Score = 103 bits (256), Expect = 7e-22
Identities = 75/193 (38%), Positives = 103/193 (53%), Gaps = 26/193 (13%)
Query: 15 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74
+KCVVVGD AVGKT L+ + A +A +Y VPTV+ D Y V V +
Sbjct: 22 LKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVTVTVGGKQH---- 69
Query: 75 DVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 132
L L+DT G D+++ R +Y +DV ++CFS+ NP S H+V+ W PE+K P
Sbjct: 70 ----LLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPH 125
Query: 133 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP-YYETSVV 191
P +L+G Q+DLR + R L KP L E G ++AK +G Y E S +
Sbjct: 126 VPYVLIGTQIDLR----DDPKTLARLLYMKEKP---LTYEHGVKLAKAIGAQCYLECSAL 178
Query: 192 AQFGIKDVFDNAI 204
Q G+K VFD AI
Sbjct: 179 TQKGLKAVFDEAI 191
>gi|229577148 ras homolog gene family, member V [Homo sapiens]
Length = 236
Score = 102 bits (253), Expect = 2e-21
Identities = 71/203 (34%), Positives = 103/203 (50%), Gaps = 23/203 (11%)
Query: 15 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74
IKCV+VGD AVGK+ LI + CN +Y+ PT A+D + V + +VD
Sbjct: 32 IKCVLVGDGAVGKSSLIVSYTCNGYPARYR------PT--ALDTFSV--------QVLVD 75
Query: 75 DVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 132
V + LWDT G DR Y +DV + CFS+ P+S ++ W PEI+ P+
Sbjct: 76 GAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQ 135
Query: 133 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 192
APV+LVG Q DLR + VN L + + + P+ K Y E S +
Sbjct: 136 APVLLVGTQADLR----DDVN-VLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALT 190
Query: 193 QFGIKDVFDNAIRAALISRRHLQ 215
Q +K+VFD+AI +A+ + L+
Sbjct: 191 QKNLKEVFDSAILSAIEHKARLE 213
>gi|115430108 rho-related BTB domain containing 3 [Homo sapiens]
Length = 611
Score = 100 bits (249), Expect = 5e-21
Identities = 74/267 (27%), Positives = 130/267 (48%), Gaps = 25/267 (9%)
Query: 429 VLKYLYTG-----ELDENER----DLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEIT 479
+L+++Y+G EL+E+ R D ++++ E ++ N L N
Sbjct: 343 ILRFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRN--------C 394
Query: 480 KAFHVRR-----TNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFV 534
K + R+ +K L K +DV F + T+ AH+ +L++ C+ MAAMF G ++
Sbjct: 395 KTYQARKPLWFYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYM 454
Query: 535 ESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYT 594
E+ + + SK + LEYLYT + M L+I A + L + E +
Sbjct: 455 EAKSVLIPVYGVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFI 514
Query: 595 VTGLME-ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM 653
+T L ++ + ++ D++ L+ A+FH + L+ W LH I TNY +K + + +
Sbjct: 515 ITQLQSMPSRELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQK--PEFQDL 572
Query: 654 SPENQEYFEKHRWPPVWYLKEEDHYQR 680
S E + + EKHRWP YLK+ Y++
Sbjct: 573 SVEERSFVEKHRWPSNMYLKQLAEYRK 599
Score = 44.7 bits (104), Expect = 3e-04
Identities = 55/227 (24%), Positives = 87/227 (38%), Gaps = 28/227 (12%)
Query: 82 LWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ 141
+WD F R G +D++V+ +++ + S H VK + P IK PVI+
Sbjct: 75 VWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIKRALNSVPVII---- 130
Query: 142 LDLRYADLEAVNRARRPLARPIKPNE---ILPPEKGREVAKELGIPYYETSVVAQFGIKD 198
A + P P+ ++ + +G ++AKELG Y E + F I
Sbjct: 131 -----AAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDFYIGK 185
Query: 199 VFDNAIR----AALISRRHLQFWKSHLRN----VQRPLLQAPFLPPKPPPPIIVVPDPPS 250
F + AL + + K + N ++ P L+ P P V+ S
Sbjct: 186 YFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQPEKMP-------VLKAEAS 238
Query: 251 SSEECPAHLLEDPLCADVILVLQERVRIF-AHKIYLSTSSSKFYDLF 296
+LL C DV+ ++ AHKI L S F LF
Sbjct: 239 HYNSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLLF 285
>gi|4885581 Rho family GTPase 2 [Homo sapiens]
Length = 227
Score = 92.4 bits (228), Expect = 1e-18
Identities = 73/211 (34%), Positives = 106/211 (50%), Gaps = 28/211 (13%)
Query: 16 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75
K VVVGD GKT L+ A +A Y VPTV+ + Y E+ +R
Sbjct: 9 KIVVVGDAECGKTALLQVFAKDAYPGSY------VPTVF--ENYTASFEIDKRR------ 54
Query: 76 VSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133
+ L +WDT G + D R AY SD V++CF I+ P +L V W E + FCP A
Sbjct: 55 --IELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNA 112
Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYE-TSVV 191
V+LVGC+LD+R DL + + P+ E+G +AK++G + Y E +S
Sbjct: 113 KVVLVGCKLDMR-TDLATLRELSKQRLIPV------THEQGTVLAKQVGAVSYVECSSRS 165
Query: 192 AQFGIKDVFDNAIRAALISRRHLQFWKSHLR 222
++ ++DVF A A+L R H Q ++ R
Sbjct: 166 SERSVRDVFHVATVASL-GRGHRQLRRTDSR 195
>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
Length = 232
Score = 88.6 bits (218), Expect = 2e-17
Identities = 73/230 (31%), Positives = 104/230 (45%), Gaps = 32/230 (13%)
Query: 9 RPNVETIKCVVVGDNAVGKTRL--ICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVL 66
+P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E
Sbjct: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLETE 57
Query: 67 ERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYP 124
E+ V L LWDT G + D R Y SD V+LCF I+ P ++ W
Sbjct: 58 EQR--------VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109
Query: 125 EIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP 184
EI +CP V+L+GC+ DLR DL + PI E+G +AK+LG
Sbjct: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPIS------YEQGCAIAKQLGAE 162
Query: 185 YY--ETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAP 232
Y ++ ++ I +F A L L KS +R++ + LL P
Sbjct: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211
>gi|4885069 ras homolog gene family, member E [Homo sapiens]
Length = 244
Score = 84.3 bits (207), Expect = 4e-16
Identities = 66/205 (32%), Positives = 100/205 (48%), Gaps = 30/205 (14%)
Query: 10 PNVETIKC--VVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE 67
PN + +KC VVVGD+ GKT L+ A + Y VPTV+ + Y E+
Sbjct: 18 PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY------VPTVF--ENYTASFEI-- 66
Query: 68 RSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPE 125
D + L LWDT G + D R +Y SD V++CF I+ P +L V W E
Sbjct: 67 ------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120
Query: 126 IKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IP 184
I+ FCP ++LVGC+ DLR D+ + P+ ++G +AK++G
Sbjct: 121 IQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVS------YDQGANMAKQIGAAT 173
Query: 185 YYETSVV-AQFGIKDVFDNAIRAAL 208
Y E S + ++ ++D+F A A +
Sbjct: 174 YIECSALQSENSVRDIFHVATLACV 198
>gi|4757770 ras homolog gene family, member H [Homo sapiens]
Length = 191
Score = 84.0 bits (206), Expect = 5e-16
Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 33/204 (16%)
Query: 12 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71
+ +IKCV+VGD+AVGKT L+ T + PTV+ V
Sbjct: 2 LSSIKCVLVGDSAVGKTSLL------VRFTSETFPEAYKPTVYENTGVDV---------- 45
Query: 72 VVDDVSVSLRLWDTFGDH--HKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 129
+D + +SL LWDT G+ R +Y ++DVV++C+S+AN NS ++K W EI+
Sbjct: 46 FMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSN 105
Query: 130 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP-YYET 188
P PV++V Q D R +RA + +G+++A+++ Y E
Sbjct: 106 LPCTPVLVVATQTDQREM---GPHRA-----------SCVNAMEGKKLAQDVRAKGYLEC 151
Query: 189 SVVAQFGIKDVFDNAIRAALISRR 212
S ++ G++ VF+ A+R A+ R
Sbjct: 152 SALSNRGVQQVFECAVRTAVNQAR 175
>gi|38016957 ras homolog gene family, member F [Homo sapiens]
Length = 211
Score = 83.6 bits (205), Expect = 6e-16
Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 26/209 (12%)
Query: 10 PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69
P + +K V+VGD GKT L+ + + Y P+V+ ++Y V +
Sbjct: 15 PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66
Query: 70 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 127
V+L L+DT G D+ + R +Y + +V++C+ + NP S +V W+PE+
Sbjct: 67 --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118
Query: 128 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYY 186
HFC P++L+GC+ DLR D E + + R PI + G +++ Y
Sbjct: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITYMQ------GLSACEQIRAALYL 171
Query: 187 ETSVVAQFGIKDVFDNAIRAALISRRHLQ 215
E S + ++DVF A + AL + + Q
Sbjct: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200
>gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens]
Length = 278
Score = 55.5 bits (132), Expect = 2e-07
Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 37/206 (17%)
Query: 15 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74
+K ++VGD+ VGK ++ + A + Y A ID Y+ +L+ R
Sbjct: 15 LKFLLVGDSDVGKGEILASLQDGAAESPYGHPA-------GID-YKTTTILLDGRR---- 62
Query: 75 DVSVSLRLWDTFGDHHKDRRF-AYGR-SDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 132
V L+LWDT G F +Y R + V+L + IAN S + W EI P
Sbjct: 63 ---VKLQLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDR-WIKEIDEHAPG 118
Query: 133 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 192
P ILVG +L L + +P E+ + A+ LG+ ++E S +
Sbjct: 119 VPKILVGNRLHLAF-------------------KRQVPTEQAQAYAERLGVTFFEVSPLC 159
Query: 193 QFGIKDVFDNAIRAALISRRHLQFWK 218
F I + F R L+ + W+
Sbjct: 160 NFNITESFTELARIVLLRHGMDRLWR 185
>gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens]
Length = 277
Score = 55.5 bits (132), Expect = 2e-07
Identities = 56/205 (27%), Positives = 87/205 (42%), Gaps = 39/205 (19%)
Query: 15 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74
+K ++VGD VGK+ ++ + A + Y L ID Y+ +L+ R
Sbjct: 15 LKFLLVGDRDVGKSEILESLQDGAAESPYSHLG-------GID-YKTTTILLDGQR---- 62
Query: 75 DVSVSLRLWDTFGDHHKDRRF-AYGR-SDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 132
V L+LWDT G F +Y R + V+L + IAN S + W +I+ P
Sbjct: 63 ---VKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDR-WIKKIEEHAPG 118
Query: 133 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 192
P ILVG +L L + +P E+ + A+ LG+ ++E S +
Sbjct: 119 VPKILVGNRLHLAF-------------------KRQVPREQAQAYAERLGVTFFEVSPLC 159
Query: 193 QFGIKDVFDNAIRAALISRRHLQFW 217
F I + F R L+ RH W
Sbjct: 160 NFNIIESFTELARIVLL--RHRMNW 182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,868,840
Number of Sequences: 37866
Number of extensions: 1503659
Number of successful extensions: 13855
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 11384
Number of HSP's gapped (non-prelim): 1505
length of query: 727
length of database: 18,247,518
effective HSP length: 110
effective length of query: 617
effective length of database: 14,082,258
effective search space: 8688753186
effective search space used: 8688753186
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.