Search of human proteins with 237649111

Search of human proteins with 237649111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237649111 Rho-related BTB domain containing 2 isoform 2
[Homo sapiens]
         (734 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...  1510   0.0  
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...  1503   0.0  
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...  1498   0.0  
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]        973   0.0  
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   130   3e-30
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   130   4e-30
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   126   6e-29
gi|46249393 ras homolog gene family, member G [Homo sapiens]          125   1e-28
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           121   2e-27
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           121   2e-27
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            121   2e-27
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   120   5e-27
gi|10835049 ras homolog gene family, member A [Homo sapiens]          119   1e-26
gi|50263042 ras-like protein TC10 [Homo sapiens]                      114   3e-25
gi|7656900 ras homolog D [Homo sapiens]                               110   4e-24
gi|111494251 ras homolog gene family, member C precursor [Homo s...   110   5e-24
gi|111494248 ras homolog gene family, member C precursor [Homo s...   110   5e-24
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   110   5e-24
gi|11034843 ras homolog gene family, member U [Homo sapiens]          105   1e-22
gi|4757764 ras homolog gene family, member B [Homo sapiens]           103   4e-22
gi|16903164 ras homolog gene family, member J [Homo sapiens]          103   7e-22
gi|229577148 ras homolog gene family, member V [Homo sapiens]         102   2e-21
gi|115430108 rho-related BTB domain containing 3 [Homo sapiens]       100   5e-21
gi|4885581 Rho family GTPase 2 [Homo sapiens]                          92   1e-18
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                     89   2e-17
gi|4885069 ras homolog gene family, member E [Homo sapiens]            84   4e-16
gi|4757770 ras homolog gene family, member H [Homo sapiens]            84   5e-16
gi|38016957 ras homolog gene family, member F [Homo sapiens]           84   6e-16
gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens]           55   2e-07
gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens]          55   2e-07

>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score = 1510 bits (3909), Expect = 0.0
 Identities = 734/734 (100%), Positives = 734/734 (100%)

Query: 1   MKARSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTV 60
           MKARSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTV
Sbjct: 1   MKARSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTV 60

Query: 61  WAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPN 120
           WAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPN
Sbjct: 61  WAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPN 120

Query: 121 SLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEK 180
           SLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEK
Sbjct: 121 SLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEK 180

Query: 181 GREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPF 240
           GREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPF
Sbjct: 181 GREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPF 240

Query: 241 LPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFY 300
           LPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFY
Sbjct: 241 LPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFY 300

Query: 301 DLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDE 360
           DLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDE
Sbjct: 301 DLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDE 360

Query: 361 AGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMV 420
           AGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMV
Sbjct: 361 AGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMV 420

Query: 421 VVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAF 480
           VVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAF
Sbjct: 421 VVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAF 480

Query: 481 MNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPF 540
           MNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPF
Sbjct: 481 MNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPF 540

Query: 541 VESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQY 600
           VESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQY
Sbjct: 541 VESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQY 600

Query: 601 TVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM 660
           TVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM
Sbjct: 601 TVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM 660

Query: 661 SPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSS 720
           SPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSS
Sbjct: 661 SPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSS 720

Query: 721 AASSSSPSSSSAVV 734
           AASSSSPSSSSAVV
Sbjct: 721 AASSSSPSSSSAVV 734


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score = 1503 bits (3890), Expect = 0.0
 Identities = 730/730 (100%), Positives = 730/730 (100%)

Query: 5   SRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAID 64
           SRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAID
Sbjct: 20  SRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAID 79

Query: 65  QYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHH 124
           QYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHH
Sbjct: 80  QYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHH 139

Query: 125 VKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREV 184
           VKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREV
Sbjct: 140 VKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREV 199

Query: 185 AKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK 244
           AKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK
Sbjct: 200 AKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK 259

Query: 245 PPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFL 304
           PPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFL
Sbjct: 260 PPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFL 319

Query: 305 MDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGS 364
           MDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGS
Sbjct: 320 MDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGS 379

Query: 365 GPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKM 424
           GPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKM
Sbjct: 380 GPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKM 439

Query: 425 DSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQE 484
           DSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQE
Sbjct: 440 DSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQE 499

Query: 485 ITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESS 544
           ITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESS
Sbjct: 500 ITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESS 559

Query: 545 TREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTG 604
           TREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTG
Sbjct: 560 TREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTG 619

Query: 605 LMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPEN 664
           LMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPEN
Sbjct: 620 LMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPEN 679

Query: 665 QEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASS 724
           QEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASS
Sbjct: 680 QEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASS 739

Query: 725 SSPSSSSAVV 734
           SSPSSSSAVV
Sbjct: 740 SSPSSSSAVV 749


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score = 1498 bits (3877), Expect = 0.0
 Identities = 727/727 (100%), Positives = 727/727 (100%)

Query: 8   MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 67
           MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR
Sbjct: 1   MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60

Query: 68  VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 127
           VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT
Sbjct: 61  VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120

Query: 128 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 187
           MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE
Sbjct: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180

Query: 188 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 247
           LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP
Sbjct: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240

Query: 248 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 307
           PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL
Sbjct: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300

Query: 308 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 367
           SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA
Sbjct: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 360

Query: 368 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 427
           GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS
Sbjct: 361 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 420

Query: 428 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 487
           IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK
Sbjct: 421 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 480

Query: 488 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 547
           AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE
Sbjct: 481 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 540

Query: 548 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 607
           VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME
Sbjct: 541 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 600

Query: 608 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 667
           ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY
Sbjct: 601 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 660

Query: 668 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 727
           FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP
Sbjct: 661 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 720

Query: 728 SSSSAVV 734
           SSSSAVV
Sbjct: 721 SSSSAVV 727


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score =  973 bits (2516), Expect = 0.0
 Identities = 483/710 (68%), Positives = 563/710 (79%), Gaps = 23/710 (3%)

Query: 8   MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 67
           MD+DMDYERPNVETIKCVVVGDNAVGKTRLICARACN TLTQYQLLATHVPTVWAIDQYR
Sbjct: 1   MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60

Query: 68  VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 127
           VCQEVLERSRDVVD+VSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSL+HVK+
Sbjct: 61  VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120

Query: 128 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 187
           MWYPEIKHFCPR PVILVGCQLDLRYADLEAVNRARRPLARPIK  +ILPPEKGREVAKE
Sbjct: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180

Query: 188 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 247
           LG+PYYETSV  QFGIKDVFDNAIRAALISRRHLQFWKSHL+ VQ+PLLQAPFLPPK PP
Sbjct: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240

Query: 248 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 307
           P+I +P+ PS      A LL++PLCADV+ +LQ++  IFAH+IYL+TSSSKFYDLFLM+ 
Sbjct: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300

Query: 308 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- 366
            E             P   +G  ++          RDF  R  S D  E  +E     P 
Sbjct: 301 EES------------PNGSEGACEK------EKQSRDFQGRILSVDPEEEREEGPPRIPQ 342

Query: 367 AGLRASTSDGILRGNG---TGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK 423
           A    S++  ++   G    G +P   + L+ WS+ F+ +  EM  +P++ +   M VV+
Sbjct: 343 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 401

Query: 424 MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ 483
           MD+S+QPGPFR +L++LYTG+LDE E+DL+ +A IAE+LE+FDLRMMV NI+N EAFMNQ
Sbjct: 402 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 461

Query: 484 EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES 543
           EITKAFHVR+ NR+KECL+KGTFSDVTF LDDG ISAHKPLLI SC+WMAAMFGG FVES
Sbjct: 462 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 521

Query: 544 STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT 603
           +  EV  P  +K  M+AVL+YLYT   + + DLD ++LI LANR CLPHLVAL EQ+ V 
Sbjct: 522 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 581

Query: 604 GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE 663
            L +A    V IDG+VL +LELAQFH A+QLA WCLHHICTNYN+VC KF +++K+ S +
Sbjct: 582 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 641

Query: 664 NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNS 713
           NQEYFE+HRWPPVWYLKEEDHYQR ++EREKED    K + +R+W FWNS
Sbjct: 642 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS 691


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  130 bits (328), Expect = 3e-30
 Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44

Query: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V+  WYPE++H 
Sbjct: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYET 195
           CP  P+ILVG +LDLR  D + + + +     PI         +G  +AKE+G + Y E 
Sbjct: 105 CPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------TYPQGLAMAKEIGAVKYLEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K VFD AIRA L
Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  130 bits (327), Expect = 4e-30
 Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44

Query: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V+  WYPE++H 
Sbjct: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYET 195
           CP  P++LVG +LDLR  D + + R R     PI         +G  +A+E+G + Y E 
Sbjct: 105 CPHTPILLVGTKLDLR-DDKDTIERLRDKKLAPI------TYPQGLAMAREIGSVKYLEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K VFD AIRA L
Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  126 bits (317), Expect = 6e-29
 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44

Query: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
           +VD   V+L LWDT G  D+ + R  +Y ++DV ++CFS+ +P S  +V+  W+PE++H 
Sbjct: 45  MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195
           CP  P+ILVG +LDLR  D + + + +     PI         +G  +AKE+  + Y E 
Sbjct: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPI------TYPQGLALAKEIDSVKYLEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K VFD AIRA L
Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  125 bits (314), Expect = 1e-28
 Identities = 77/200 (38%), Positives = 115/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           +++IKCVVVGD AVGKT L+     NA   +Y      +PTV+  D Y         ++ 
Sbjct: 1   MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44

Query: 79  VVDDVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
            VD  +V+L LWDT G    DR    +Y +++V V+CFSIA+P S  +V+  W+PE+ H 
Sbjct: 45  AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195
           CP  P++LVG + DLR A  + + R +     PI       P++G+ +AK++  + Y E 
Sbjct: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K+VF  A+RA L
Sbjct: 158 SALQQDGVKEVFAEAVRAVL 177


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  121 bits (304), Expect = 2e-27
 Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++TIKCVVVGD AVGKT L+ +   N   ++Y      VPTV+  D Y V          
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44

Query: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
           ++     +L L+DT G  D+ + R  +Y ++DV ++CFS+ +P+S  +VK  W PEI H 
Sbjct: 45  MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195
           CP+ P +LVG Q+DLR  D   + +  +   +PI       PE   ++A++L  + Y E 
Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K+VFD AI AAL
Sbjct: 158 SALTQRGLKNVFDEAILAAL 177


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  121 bits (304), Expect = 2e-27
 Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++TIKCVVVGD AVGKT L+ +   N   ++Y      VPTV+  D Y V          
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44

Query: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
           ++     +L L+DT G  D+ + R  +Y ++DV ++CFS+ +P+S  +VK  W PEI H 
Sbjct: 45  MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195
           CP+ P +LVG Q+DLR  D   + +  +   +PI       PE   ++A++L  + Y E 
Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K+VFD AI AAL
Sbjct: 158 SALTQKGLKNVFDEAILAAL 177


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  121 bits (304), Expect = 2e-27
 Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++TIKCVVVGD AVGKT L+ +   N   ++Y      VPTV+  D Y V          
Sbjct: 1   MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44

Query: 79  VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
           ++     +L L+DT G  D+ + R  +Y ++DV ++CFS+ +P+S  +VK  W PEI H 
Sbjct: 45  MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 195
           CP+ P +LVG Q+DLR  D   + +  +   +PI       PE   ++A++L  + Y E 
Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157

Query: 196 SVVAQFGIKDVFDNAIRAAL 215
           S + Q G+K+VFD AI AAL
Sbjct: 158 SALTQKGLKNVFDEAILAAL 177


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  120 bits (301), Expect = 5e-27
 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           ++ IKCVVVGD AVGKT L+ +   NA   +Y      +PTV+  D Y         +  
Sbjct: 1   MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44

Query: 79  VVDDVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 117
           +VD   V+L LWDT G    DR             YG+           +DV ++CFS+ 
Sbjct: 45  MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104

Query: 118 NPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILP 177
           +P S  +V+  WYPE++H CP  P+ILVG +LDLR  D + + + +     PI       
Sbjct: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------T 157

Query: 178 PEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAAL 215
             +G  +AKE+G + Y E S + Q G+K VFD AIRA L
Sbjct: 158 YPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  119 bits (298), Expect = 1e-26
 Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 26/200 (13%)

Query: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50

Query: 83  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110

Query: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVA 199
           P+ILVG + DLR  +       RR LA+     E + PE+GR++A  +G   Y E S   
Sbjct: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163

Query: 200 QFGIKDVFDNAIRAALISRR 219
           + G+++VF+ A RAAL +RR
Sbjct: 164 KDGVREVFEMATRAALQARR 183


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  114 bits (285), Expect = 3e-25
 Identities = 79/207 (38%), Positives = 111/207 (53%), Gaps = 26/207 (12%)

Query: 17  PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 76
           P    +KCVVVGD AVGKT L+ + A +A   +Y      VPTV+  D Y V        
Sbjct: 5   PGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVSV------ 50

Query: 77  RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 134
              V      L L+DT G  D+ + R  +Y  +DV ++CFS+ NP S  +VK  W PE+K
Sbjct: 51  --TVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELK 108

Query: 135 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYY 193
            + P  P +L+G Q+DLR  D + + R      +PI        E+G+++AKE+G   Y 
Sbjct: 109 EYAPNVPFLLIGTQIDLR-DDPKTLARLNDMKEKPI------CVEQGQKLAKEIGACCYV 161

Query: 194 ETSVVAQFGIKDVFDNAIRAALISRRH 220
           E S + Q G+K VFD AI A L  ++H
Sbjct: 162 ECSALTQKGLKTVFDEAIIAILTPKKH 188


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  110 bits (276), Expect = 4e-24
 Identities = 73/212 (34%), Positives = 108/212 (50%), Gaps = 27/212 (12%)

Query: 17  PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 76
           P V ++K V+VGD   GKT L+   A  A    Y       PTV+  ++Y V  +V  + 
Sbjct: 13  PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESY------TPTVF--ERYMVNLQVKGKP 64

Query: 77  RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 134
                   V L +WDT G  D+ + R   Y  + V++LCF + +PNS  ++   WYPE+ 
Sbjct: 65  --------VHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVN 116

Query: 135 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYY 193
           HFC + P+I+VGC+ DLR  D   VN+ RR    P+  +      +G+E+A+ +G + Y 
Sbjct: 117 HFCKKVPIIVVGCKTDLR-KDKSLVNKLRRNGLEPVTYH------RGQEMARSVGAVAYL 169

Query: 194 ETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 225
           E S      +  VF  A   AL SR    FW+
Sbjct: 170 ECSARLHDNVHAVFQEAAEVALSSRGR-NFWR 200


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  110 bits (275), Expect = 5e-24
 Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%)

Query: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50

Query: 83  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110

Query: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 199
           P+ILVG + DLR  +       RR LA+     E +  E+GR++A  +    Y E S   
Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163

Query: 200 QFGIKDVFDNAIRAALISRRH 220
           + G+++VF+ A RA L  R++
Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  110 bits (275), Expect = 5e-24
 Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%)

Query: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50

Query: 83  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110

Query: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 199
           P+ILVG + DLR  +       RR LA+     E +  E+GR++A  +    Y E S   
Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163

Query: 200 QFGIKDVFDNAIRAALISRRH 220
           + G+++VF+ A RA L  R++
Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  110 bits (275), Expect = 5e-24
 Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%)

Query: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50

Query: 83  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110

Query: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 199
           P+ILVG + DLR  +       RR LA+     E +  E+GR++A  +    Y E S   
Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163

Query: 200 QFGIKDVFDNAIRAALISRRH 220
           + G+++VF+ A RA L  R++
Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  105 bits (263), Expect = 1e-22
 Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 26/197 (13%)

Query: 22  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 81
           +KCV+VGD AVGKT L+ +   N   T+Y      +PT  A D +     V        D
Sbjct: 50  VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93

Query: 82  DVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 139
              V L+L DT G    D  R   Y  +D+ +LCFS+ +P+S  +V   W PEI+  CP+
Sbjct: 94  GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153

Query: 140 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVV 198
           AP+ILVG Q DLR  D++ +    +   +P+      P E  +  A+E+    Y E S +
Sbjct: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206

Query: 199 AQFGIKDVFDNAIRAAL 215
            Q  +K+VFD AI A +
Sbjct: 207 TQKNLKEVFDAAIVAGI 223


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  103 bits (258), Expect = 4e-22
 Identities = 72/199 (36%), Positives = 104/199 (52%), Gaps = 26/199 (13%)

Query: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82
           K VVVGD A GKT L+         ++ +    +VPTV+  + Y    EV        D 
Sbjct: 7   KLVVVGDGACGKTCLLIV------FSKDEFPEVYVPTVF--ENYVADIEV--------DG 50

Query: 83  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140
             V L LWDT G  D+ + R  +Y  +DV+++CFS+ +P+SL ++   W PE+KHFCP  
Sbjct: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNV 110

Query: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 199
           P+ILV  + DLR     +    R  LAR     E +  + GR +A  +    Y E S   
Sbjct: 111 PIILVANKKDLR-----SDEHVRTELAR--MKQEPVRTDDGRAMAVRIQAYDYLECSAKT 163

Query: 200 QFGIKDVFDNAIRAALISR 218
           + G+++VF+ A RAAL  R
Sbjct: 164 KEGVREVFETATRAALQKR 182


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  103 bits (256), Expect = 7e-22
 Identities = 75/193 (38%), Positives = 103/193 (53%), Gaps = 26/193 (13%)

Query: 22  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 81
           +KCVVVGD AVGKT L+ + A +A   +Y      VPTV+  D Y V   V  +      
Sbjct: 22  LKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVTVTVGGKQH---- 69

Query: 82  DVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 139
                L L+DT G  D+++ R  +Y  +DV ++CFS+ NP S H+V+  W PE+K   P 
Sbjct: 70  ----LLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPH 125

Query: 140 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP-YYETSVV 198
            P +L+G Q+DLR    +      R L    KP   L  E G ++AK +G   Y E S +
Sbjct: 126 VPYVLIGTQIDLR----DDPKTLARLLYMKEKP---LTYEHGVKLAKAIGAQCYLECSAL 178

Query: 199 AQFGIKDVFDNAI 211
            Q G+K VFD AI
Sbjct: 179 TQKGLKAVFDEAI 191


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  102 bits (253), Expect = 2e-21
 Identities = 71/203 (34%), Positives = 103/203 (50%), Gaps = 23/203 (11%)

Query: 22  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 81
           IKCV+VGD AVGK+ LI +  CN    +Y+      PT  A+D + V        + +VD
Sbjct: 32  IKCVLVGDGAVGKSSLIVSYTCNGYPARYR------PT--ALDTFSV--------QVLVD 75

Query: 82  DVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 139
              V + LWDT G    DR     Y  +DV + CFS+  P+S  ++   W PEI+   P+
Sbjct: 76  GAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQ 135

Query: 140 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 199
           APV+LVG Q DLR    + VN     L +  +   +  P+      K     Y E S + 
Sbjct: 136 APVLLVGTQADLR----DDVN-VLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALT 190

Query: 200 QFGIKDVFDNAIRAALISRRHLQ 222
           Q  +K+VFD+AI +A+  +  L+
Sbjct: 191 QKNLKEVFDSAILSAIEHKARLE 213


>gi|115430108 rho-related BTB domain containing 3 [Homo sapiens]
          Length = 611

 Score =  100 bits (249), Expect = 5e-21
 Identities = 74/267 (27%), Positives = 130/267 (48%), Gaps = 25/267 (9%)

Query: 436 VLKYLYTG-----ELDENER----DLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEIT 486
           +L+++Y+G     EL+E+ R    D   ++++ E ++         N L N         
Sbjct: 343 ILRFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRN--------C 394

Query: 487 KAFHVRR-----TNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFV 541
           K +  R+        +K  L K   +DV F +   T+ AH+ +L++ C+ MAAMF G ++
Sbjct: 395 KTYQARKPLWFYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYM 454

Query: 542 ESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYT 601
           E+ +  +     SK    + LEYLYT     +     M L+I A    +  L  + E + 
Sbjct: 455 EAKSVLIPVYGVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFI 514

Query: 602 VTGLME-ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM 660
           +T L    ++ +  ++ D++  L+ A+FH +  L+ W LH I TNY    +K   + + +
Sbjct: 515 ITQLQSMPSRELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQK--PEFQDL 572

Query: 661 SPENQEYFEKHRWPPVWYLKEEDHYQR 687
           S E + + EKHRWP   YLK+   Y++
Sbjct: 573 SVEERSFVEKHRWPSNMYLKQLAEYRK 599



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 55/227 (24%), Positives = 87/227 (38%), Gaps = 28/227 (12%)

Query: 89  LWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ 148
           +WD F       R   G +D++V+ +++ +  S H VK  + P IK      PVI+    
Sbjct: 75  VWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIKRALNSVPVII---- 130

Query: 149 LDLRYADLEAVNRARRPLARPIKPNE---ILPPEKGREVAKELGIPYYETSVVAQFGIKD 205
                A +        P   P+  ++    +   +G ++AKELG  Y E   +  F I  
Sbjct: 131 -----AAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDFYIGK 185

Query: 206 VFDNAIR----AALISRRHLQFWKSHLRN----VQRPLLQAPFLPPKPPPPIIVVPDPPS 257
            F   +      AL  +   +  K  + N    ++ P L+ P   P       V+    S
Sbjct: 186 YFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQPEKMP-------VLKAEAS 238

Query: 258 SSEECPAHLLEDPLCADVILVLQERVRIF-AHKIYLSTSSSKFYDLF 303
                  +LL    C DV+       ++  AHKI L   S  F  LF
Sbjct: 239 HYNSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLLF 285


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 73/211 (34%), Positives = 106/211 (50%), Gaps = 28/211 (13%)

Query: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82
           K VVVGD   GKT L+   A +A    Y      VPTV+  + Y    E+ +R       
Sbjct: 9   KIVVVGDAECGKTALLQVFAKDAYPGSY------VPTVF--ENYTASFEIDKRR------ 54

Query: 83  VSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140
             + L +WDT G  + D  R  AY  SD V++CF I+ P +L  V   W  E + FCP A
Sbjct: 55  --IELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNA 112

Query: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYE-TSVV 198
            V+LVGC+LD+R  DL  +    +    P+        E+G  +AK++G + Y E +S  
Sbjct: 113 KVVLVGCKLDMR-TDLATLRELSKQRLIPV------THEQGTVLAKQVGAVSYVECSSRS 165

Query: 199 AQFGIKDVFDNAIRAALISRRHLQFWKSHLR 229
           ++  ++DVF  A  A+L  R H Q  ++  R
Sbjct: 166 SERSVRDVFHVATVASL-GRGHRQLRRTDSR 195


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 73/230 (31%), Positives = 104/230 (45%), Gaps = 32/230 (13%)

Query: 16  RPNVETIKCVVVGDNAVGKTRL--ICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVL 73
           +P V   K V+VGD   GKT +  + A+ C           T+VPTV+  + Y  C E  
Sbjct: 8   QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLETE 57

Query: 74  ERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYP 131
           E+         V L LWDT G  + D  R   Y  SD V+LCF I+ P ++      W  
Sbjct: 58  EQR--------VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109

Query: 132 EIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP 191
           EI  +CP   V+L+GC+ DLR  DL  +         PI        E+G  +AK+LG  
Sbjct: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPIS------YEQGCAIAKQLGAE 162

Query: 192 YY--ETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAP 239
            Y   ++  ++  I  +F  A    L     L   KS +R++ + LL  P
Sbjct: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 66/205 (32%), Positives = 100/205 (48%), Gaps = 30/205 (14%)

Query: 17  PNVETIKC--VVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLE 74
           PN + +KC  VVVGD+  GKT L+   A +     Y      VPTV+  + Y    E+  
Sbjct: 18  PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY------VPTVF--ENYTASFEI-- 66

Query: 75  RSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPE 132
                 D   + L LWDT G  + D  R  +Y  SD V++CF I+ P +L  V   W  E
Sbjct: 67  ------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120

Query: 133 IKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IP 191
           I+ FCP   ++LVGC+ DLR  D+  +         P+        ++G  +AK++G   
Sbjct: 121 IQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVS------YDQGANMAKQIGAAT 173

Query: 192 YYETSVV-AQFGIKDVFDNAIRAAL 215
           Y E S + ++  ++D+F  A  A +
Sbjct: 174 YIECSALQSENSVRDIFHVATLACV 198


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 33/204 (16%)

Query: 19  VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 78
           + +IKCV+VGD+AVGKT L+         T       + PTV+      V          
Sbjct: 2   LSSIKCVLVGDSAVGKTSLL------VRFTSETFPEAYKPTVYENTGVDV---------- 45

Query: 79  VVDDVSVSLRLWDTFGDH--HKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 136
            +D + +SL LWDT G+      R  +Y ++DVV++C+S+AN NS  ++K  W  EI+  
Sbjct: 46  FMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSN 105

Query: 137 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP-YYET 195
            P  PV++V  Q D R       +RA             +   +G+++A+++    Y E 
Sbjct: 106 LPCTPVLVVATQTDQREM---GPHRA-----------SCVNAMEGKKLAQDVRAKGYLEC 151

Query: 196 SVVAQFGIKDVFDNAIRAALISRR 219
           S ++  G++ VF+ A+R A+   R
Sbjct: 152 SALSNRGVQQVFECAVRTAVNQAR 175


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 26/209 (12%)

Query: 17  PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 76
           P  + +K V+VGD   GKT L+   +  +    Y       P+V+  ++Y     V  + 
Sbjct: 15  PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66

Query: 77  RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 134
                   V+L L+DT G  D+ + R  +Y  + +V++C+ + NP S  +V   W+PE+ 
Sbjct: 67  --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118

Query: 135 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYY 193
           HFC   P++L+GC+ DLR  D E + + R     PI   +      G    +++    Y 
Sbjct: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITYMQ------GLSACEQIRAALYL 171

Query: 194 ETSVVAQFGIKDVFDNAIRAALISRRHLQ 222
           E S   +  ++DVF  A + AL + +  Q
Sbjct: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200


>gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens]
          Length = 278

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 37/206 (17%)

Query: 22  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 81
           +K ++VGD+ VGK  ++ +    A  + Y   A        ID Y+    +L+  R    
Sbjct: 15  LKFLLVGDSDVGKGEILASLQDGAAESPYGHPA-------GID-YKTTTILLDGRR---- 62

Query: 82  DVSVSLRLWDTFGDHHKDRRF-AYGR-SDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 139
              V L+LWDT G       F +Y R +  V+L + IAN  S   +   W  EI    P 
Sbjct: 63  ---VKLQLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDR-WIKEIDEHAPG 118

Query: 140 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 199
            P ILVG +L L +                      +P E+ +  A+ LG+ ++E S + 
Sbjct: 119 VPKILVGNRLHLAF-------------------KRQVPTEQAQAYAERLGVTFFEVSPLC 159

Query: 200 QFGIKDVFDNAIRAALISRRHLQFWK 225
            F I + F    R  L+     + W+
Sbjct: 160 NFNITESFTELARIVLLRHGMDRLWR 185


>gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens]
          Length = 277

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 56/205 (27%), Positives = 87/205 (42%), Gaps = 39/205 (19%)

Query: 22  IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 81
           +K ++VGD  VGK+ ++ +    A  + Y  L         ID Y+    +L+  R    
Sbjct: 15  LKFLLVGDRDVGKSEILESLQDGAAESPYSHLG-------GID-YKTTTILLDGQR---- 62

Query: 82  DVSVSLRLWDTFGDHHKDRRF-AYGR-SDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 139
              V L+LWDT G       F +Y R +  V+L + IAN  S   +   W  +I+   P 
Sbjct: 63  ---VKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDR-WIKKIEEHAPG 118

Query: 140 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 199
            P ILVG +L L +                      +P E+ +  A+ LG+ ++E S + 
Sbjct: 119 VPKILVGNRLHLAF-------------------KRQVPREQAQAYAERLGVTFFEVSPLC 159

Query: 200 QFGIKDVFDNAIRAALISRRHLQFW 224
            F I + F    R  L+  RH   W
Sbjct: 160 NFNIIESFTELARIVLL--RHRMNW 182


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,988,898
Number of Sequences: 37866
Number of extensions: 1509526
Number of successful extensions: 13875
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 11404
Number of HSP's gapped (non-prelim): 1506
length of query: 734
length of database: 18,247,518
effective HSP length: 110
effective length of query: 624
effective length of database: 14,082,258
effective search space: 8787328992
effective search space used: 8787328992
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.