BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo sapiens] (749 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo... 1543 0.0 gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo... 1503 0.0 gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo... 1498 0.0 gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] 973 0.0 gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra... 130 3e-30 gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil... 130 4e-30 gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi... 126 6e-29 gi|46249393 ras homolog gene family, member G [Homo sapiens] 125 1e-28 gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] 121 2e-27 gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] 121 2e-27 gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] 121 2e-27 gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra... 120 5e-27 gi|10835049 ras homolog gene family, member A [Homo sapiens] 119 1e-26 gi|50263042 ras-like protein TC10 [Homo sapiens] 114 3e-25 gi|7656900 ras homolog D [Homo sapiens] 110 4e-24 gi|111494251 ras homolog gene family, member C precursor [Homo s... 110 5e-24 gi|111494248 ras homolog gene family, member C precursor [Homo s... 110 5e-24 gi|28395033 ras homolog gene family, member C precursor [Homo sa... 110 5e-24 gi|11034843 ras homolog gene family, member U [Homo sapiens] 105 1e-22 gi|4757764 ras homolog gene family, member B [Homo sapiens] 103 4e-22 gi|16903164 ras homolog gene family, member J [Homo sapiens] 103 8e-22 gi|229577148 ras homolog gene family, member V [Homo sapiens] 102 2e-21 gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] 100 5e-21 gi|4885581 Rho family GTPase 2 [Homo sapiens] 92 1e-18 gi|7657514 GTP-binding protein RHO6 [Homo sapiens] 89 2e-17 gi|4885069 ras homolog gene family, member E [Homo sapiens] 85 3e-16 gi|4757770 ras homolog gene family, member H [Homo sapiens] 84 5e-16 gi|38016957 ras homolog gene family, member F [Homo sapiens] 84 6e-16 gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens] 55 2e-07 gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens] 55 2e-07 >gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo sapiens] Length = 749 Score = 1543 bits (3995), Expect = 0.0 Identities = 749/749 (100%), Positives = 749/749 (100%) Query: 1 MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA 60 MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA Sbjct: 1 MQAWRKGPDGPQKTSSDSMSRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNA 60 Query: 61 TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG 120 TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG Sbjct: 61 TLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYG 120 Query: 121 RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP 180 RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP Sbjct: 121 RSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRP 180 Query: 181 LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 240 LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK Sbjct: 181 LARPIKPNEILPPEKGREVAKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 240 Query: 241 SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI 300 SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI Sbjct: 241 SHLRNVQRPLLQAPFLPPKPPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRI 300 Query: 301 FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF 360 FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF Sbjct: 301 FAHKIYLSTSSSKFYDLFLMDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDF 360 Query: 361 LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE 420 LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE Sbjct: 361 LLRAASFDVCESVDEAGGSGPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQE 420 Query: 421 EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF 480 EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF Sbjct: 421 EMAEDPLTYKSRLMVVVKMDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVF 480 Query: 481 DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL 540 DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL Sbjct: 481 DLRMMVANILNNEAFMNQEITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLL 540 Query: 541 ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA 600 ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA Sbjct: 541 ISSCDWMAAMFGGPFVESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILA 600 Query: 601 NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN 660 NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN Sbjct: 601 NRLCLPHLVALTEQYTVTGLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTN 660 Query: 661 YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK 720 YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK Sbjct: 661 YNNVCRKFPRDMKAMSPENQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPK 720 Query: 721 RRWLFWNSPSSPSSSAASSSSPSSSSAVV 749 RRWLFWNSPSSPSSSAASSSSPSSSSAVV Sbjct: 721 RRWLFWNSPSSPSSSAASSSSPSSSSAVV 749 >gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo sapiens] Length = 734 Score = 1503 bits (3890), Expect = 0.0 Identities = 730/730 (100%), Positives = 730/730 (100%) Query: 20 SRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAID 79 SRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAID Sbjct: 5 SRLMDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAID 64 Query: 80 QYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHH 139 QYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHH Sbjct: 65 QYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHH 124 Query: 140 VKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREV 199 VKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREV Sbjct: 125 VKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREV 184 Query: 200 AKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK 259 AKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK Sbjct: 185 AKELGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPK 244 Query: 260 PPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFL 319 PPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFL Sbjct: 245 PPPPIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFL 304 Query: 320 MDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGS 379 MDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGS Sbjct: 305 MDLSEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGS 364 Query: 380 GPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKM 439 GPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKM Sbjct: 365 GPAGLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKM 424 Query: 440 DSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQE 499 DSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQE Sbjct: 425 DSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQE 484 Query: 500 ITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESS 559 ITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESS Sbjct: 485 ITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESS 544 Query: 560 TREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTG 619 TREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTG Sbjct: 545 TREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTG 604 Query: 620 LMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPEN 679 LMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPEN Sbjct: 605 LMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPEN 664 Query: 680 QEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASS 739 QEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASS Sbjct: 665 QEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASS 724 Query: 740 SSPSSSSAVV 749 SSPSSSSAVV Sbjct: 725 SSPSSSSAVV 734 >gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo sapiens] Length = 727 Score = 1498 bits (3877), Expect = 0.0 Identities = 727/727 (100%), Positives = 727/727 (100%) Query: 23 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 82 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR Sbjct: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60 Query: 83 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 142 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT Sbjct: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120 Query: 143 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 202 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE Sbjct: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180 Query: 203 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 262 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP Sbjct: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240 Query: 263 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 322 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL Sbjct: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300 Query: 323 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 382 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA Sbjct: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGPA 360 Query: 383 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 442 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS Sbjct: 361 GLRASTSDGILRGNGTGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVKMDSS 420 Query: 443 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 502 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK Sbjct: 421 IQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEITK 480 Query: 503 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 562 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE Sbjct: 481 AFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVESSTRE 540 Query: 563 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 622 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME Sbjct: 541 VVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVTGLME 600 Query: 623 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 682 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY Sbjct: 601 ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPENQEY 660 Query: 683 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 742 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP Sbjct: 661 FEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNSPSSPSSSAASSSSP 720 Query: 743 SSSSAVV 749 SSSSAVV Sbjct: 721 SSSSAVV 727 >gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] Length = 696 Score = 973 bits (2516), Expect = 0.0 Identities = 483/710 (68%), Positives = 563/710 (79%), Gaps = 23/710 (3%) Query: 23 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 82 MD+DMDYERPNVETIKCVVVGDNAVGKTRLICARACN TLTQYQLLATHVPTVWAIDQYR Sbjct: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60 Query: 83 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 142 VCQEVLERSRDVVD+VSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSL+HVK+ Sbjct: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120 Query: 143 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 202 MWYPEIKHFCPR PVILVGCQLDLRYADLEAVNRARRPLARPIK +ILPPEKGREVAKE Sbjct: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180 Query: 203 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 262 LG+PYYETSV QFGIKDVFDNAIRAALISRRHLQFWKSHL+ VQ+PLLQAPFLPPK PP Sbjct: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240 Query: 263 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 322 P+I +P+ PS A LL++PLCADV+ +LQ++ IFAH+IYL+TSSSKFYDLFLM+ Sbjct: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300 Query: 323 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- 381 E P +G ++ RDF R S D E +E P Sbjct: 301 EES------------PNGSEGACEK------EKQSRDFQGRILSVDPEEEREEGPPRIPQ 342 Query: 382 AGLRASTSDGILRGNG---TGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK 438 A S++ ++ G G +P + L+ WS+ F+ + EM +P++ + M VV+ Sbjct: 343 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 401 Query: 439 MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ 498 MD+S+QPGPFR +L++LYTG+LDE E+DL+ +A IAE+LE+FDLRMMV NI+N EAFMNQ Sbjct: 402 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 461 Query: 499 EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES 558 EITKAFHVR+ NR+KECL+KGTFSDVTF LDDG ISAHKPLLI SC+WMAAMFGG FVES Sbjct: 462 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 521 Query: 559 STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT 618 + EV P +K M+AVL+YLYT + + DLD ++LI LANR CLPHLVAL EQ+ V Sbjct: 522 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 581 Query: 619 GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE 678 L +A V IDG+VL +LELAQFH A+QLA WCLHHICTNYN+VC KF +++K+ S + Sbjct: 582 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 641 Query: 679 NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNS 728 NQEYFE+HRWPPVWYLKEEDHYQR ++EREKED K + +R+W FWNS Sbjct: 642 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS 691 >gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1 [Homo sapiens] Length = 192 Score = 130 bits (328), Expect = 3e-30 Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 94 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 +VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V+ WYPE++H Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYET 210 CP P+ILVG +LDLR D + + + + PI +G +AKE+G + Y E Sbjct: 105 CPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------TYPQGLAMAKEIGAVKYLEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K VFD AIRA L Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177 >gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) [Homo sapiens] Length = 192 Score = 130 bits (327), Expect = 4e-30 Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 94 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 +VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V+ WYPE++H Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYET 210 CP P++LVG +LDLR D + + R R PI +G +A+E+G + Y E Sbjct: 105 CPHTPILLVGTKLDLR-DDKDTIERLRDKKLAPI------TYPQGLAMAREIGSVKYLEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K VFD AIRA L Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177 >gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapiens] Length = 192 Score = 126 bits (317), Expect = 6e-29 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 94 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 +VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V+ W+PE++H Sbjct: 45 MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210 CP P+ILVG +LDLR D + + + + PI +G +AKE+ + Y E Sbjct: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPI------TYPQGLALAKEIDSVKYLEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K VFD AIRA L Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177 >gi|46249393 ras homolog gene family, member G [Homo sapiens] Length = 191 Score = 125 bits (314), Expect = 1e-28 Identities = 77/200 (38%), Positives = 115/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 +++IKCVVVGD AVGKT L+ NA +Y +PTV+ D Y ++ Sbjct: 1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44 Query: 94 VVDDVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 VD +V+L LWDT G DR +Y +++V V+CFSIA+P S +V+ W+PE+ H Sbjct: 45 AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210 CP P++LVG + DLR A + + R + PI P++G+ +AK++ + Y E Sbjct: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K+VF A+RA L Sbjct: 158 SALQQDGVKEVFAEAVRAVL 177 >gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] Length = 191 Score = 121 bits (304), Expect = 2e-27 Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44 Query: 94 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 ++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210 CP+ P +LVG Q+DLR D + + + +PI PE ++A++L + Y E Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K+VFD AI AAL Sbjct: 158 SALTQRGLKNVFDEAILAAL 177 >gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] Length = 191 Score = 121 bits (304), Expect = 2e-27 Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44 Query: 94 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 ++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210 CP+ P +LVG Q+DLR D + + + +PI PE ++A++L + Y E Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K+VFD AI AAL Sbjct: 158 SALTQKGLKNVFDEAILAAL 177 >gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] Length = 191 Score = 121 bits (304), Expect = 2e-27 Identities = 77/200 (38%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44 Query: 94 VVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 ++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYET 210 CP+ P +LVG Q+DLR D + + + +PI PE ++A++L + Y E Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157 Query: 211 SVVAQFGIKDVFDNAIRAAL 230 S + Q G+K+VFD AI AAL Sbjct: 158 SALTQKGLKNVFDEAILAAL 177 >gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b [Homo sapiens] Length = 211 Score = 120 bits (301), Expect = 5e-27 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 ++ IKCVVVGD AVGKT L+ + NA +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 94 VVDDVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 132 +VD V+L LWDT G DR YG+ +DV ++CFS+ Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104 Query: 133 NPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILP 192 +P S +V+ WYPE++H CP P+ILVG +LDLR D + + + + PI Sbjct: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPI------T 157 Query: 193 PEKGREVAKELG-IPYYETSVVAQFGIKDVFDNAIRAAL 230 +G +AKE+G + Y E S + Q G+K VFD AIRA L Sbjct: 158 YPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196 >gi|10835049 ras homolog gene family, member A [Homo sapiens] Length = 193 Score = 119 bits (298), Expect = 1e-26 Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 26/200 (13%) Query: 38 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50 Query: 98 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVA 214 P+ILVG + DLR + RR LA+ E + PE+GR++A +G Y E S Sbjct: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163 Query: 215 QFGIKDVFDNAIRAALISRR 234 + G+++VF+ A RAAL +RR Sbjct: 164 KDGVREVFEMATRAALQARR 183 >gi|50263042 ras-like protein TC10 [Homo sapiens] Length = 205 Score = 114 bits (285), Expect = 3e-25 Identities = 79/207 (38%), Positives = 111/207 (53%), Gaps = 26/207 (12%) Query: 32 PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 91 P +KCVVVGD AVGKT L+ + A +A +Y VPTV+ D Y V Sbjct: 5 PGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVSV------ 50 Query: 92 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 149 V L L+DT G D+ + R +Y +DV ++CFS+ NP S +VK W PE+K Sbjct: 51 --TVGGKQYLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELK 108 Query: 150 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYY 208 + P P +L+G Q+DLR D + + R +PI E+G+++AKE+G Y Sbjct: 109 EYAPNVPFLLIGTQIDLR-DDPKTLARLNDMKEKPI------CVEQGQKLAKEIGACCYV 161 Query: 209 ETSVVAQFGIKDVFDNAIRAALISRRH 235 E S + Q G+K VFD AI A L ++H Sbjct: 162 ECSALTQKGLKTVFDEAIIAILTPKKH 188 >gi|7656900 ras homolog D [Homo sapiens] Length = 210 Score = 110 bits (276), Expect = 4e-24 Identities = 73/212 (34%), Positives = 108/212 (50%), Gaps = 27/212 (12%) Query: 32 PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 91 P V ++K V+VGD GKT L+ A A Y PTV+ ++Y V +V + Sbjct: 13 PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESY------TPTVF--ERYMVNLQVKGKP 64 Query: 92 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 149 V L +WDT G D+ + R Y + V++LCF + +PNS ++ WYPE+ Sbjct: 65 --------VHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVN 116 Query: 150 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYY 208 HFC + P+I+VGC+ DLR D VN+ RR P+ + +G+E+A+ +G + Y Sbjct: 117 HFCKKVPIIVVGCKTDLR-KDKSLVNKLRRNGLEPVTYH------RGQEMARSVGAVAYL 169 Query: 209 ETSVVAQFGIKDVFDNAIRAALISRRHLQFWK 240 E S + VF A AL SR FW+ Sbjct: 170 ECSARLHDNVHAVFQEAAEVALSSRGR-NFWR 200 >gi|111494251 ras homolog gene family, member C precursor [Homo sapiens] Length = 193 Score = 110 bits (275), Expect = 5e-24 Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%) Query: 38 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50 Query: 98 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 214 P+ILVG + DLR + RR LA+ E + E+GR++A + Y E S Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163 Query: 215 QFGIKDVFDNAIRAALISRRH 235 + G+++VF+ A RA L R++ Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184 >gi|111494248 ras homolog gene family, member C precursor [Homo sapiens] Length = 193 Score = 110 bits (275), Expect = 5e-24 Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%) Query: 38 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50 Query: 98 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 214 P+ILVG + DLR + RR LA+ E + E+GR++A + Y E S Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163 Query: 215 QFGIKDVFDNAIRAALISRRH 235 + G+++VF+ A RA L R++ Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184 >gi|28395033 ras homolog gene family, member C precursor [Homo sapiens] Length = 193 Score = 110 bits (275), Expect = 5e-24 Identities = 74/201 (36%), Positives = 109/201 (54%), Gaps = 26/201 (12%) Query: 38 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50 Query: 98 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 214 P+ILVG + DLR + RR LA+ E + E+GR++A + Y E S Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163 Query: 215 QFGIKDVFDNAIRAALISRRH 235 + G+++VF+ A RA L R++ Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184 >gi|11034843 ras homolog gene family, member U [Homo sapiens] Length = 258 Score = 105 bits (263), Expect = 1e-22 Identities = 71/197 (36%), Positives = 102/197 (51%), Gaps = 26/197 (13%) Query: 37 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 96 +KCV+VGD AVGKT L+ + N T+Y +PT A D + V D Sbjct: 50 VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93 Query: 97 DVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154 V L+L DT G D R Y +D+ +LCFS+ +P+S +V W PEI+ CP+ Sbjct: 94 GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153 Query: 155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVV 213 AP+ILVG Q DLR D++ + + +P+ P E + A+E+ Y E S + Sbjct: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206 Query: 214 AQFGIKDVFDNAIRAAL 230 Q +K+VFD AI A + Sbjct: 207 TQKNLKEVFDAAIVAGI 223 >gi|4757764 ras homolog gene family, member B [Homo sapiens] Length = 196 Score = 103 bits (258), Expect = 4e-22 Identities = 72/199 (36%), Positives = 104/199 (52%), Gaps = 26/199 (13%) Query: 38 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97 K VVVGD A GKT L+ ++ + +VPTV+ + Y EV D Sbjct: 7 KLVVVGDGACGKTCLLIV------FSKDEFPEVYVPTVF--ENYVADIEV--------DG 50 Query: 98 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155 V L LWDT G D+ + R +Y +DV+++CFS+ +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNV 110 Query: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYYETSVVA 214 P+ILV + DLR + R LAR E + + GR +A + Y E S Sbjct: 111 PIILVANKKDLR-----SDEHVRTELAR--MKQEPVRTDDGRAMAVRIQAYDYLECSAKT 163 Query: 215 QFGIKDVFDNAIRAALISR 233 + G+++VF+ A RAAL R Sbjct: 164 KEGVREVFETATRAALQKR 182 >gi|16903164 ras homolog gene family, member J [Homo sapiens] Length = 214 Score = 103 bits (256), Expect = 8e-22 Identities = 75/193 (38%), Positives = 103/193 (53%), Gaps = 26/193 (13%) Query: 37 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 96 +KCVVVGD AVGKT L+ + A +A +Y VPTV+ D Y V V + Sbjct: 22 LKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVTVTVGGKQH---- 69 Query: 97 DVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154 L L+DT G D+++ R +Y +DV ++CFS+ NP S H+V+ W PE+K P Sbjct: 70 ----LLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPH 125 Query: 155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP-YYETSVV 213 P +L+G Q+DLR + R L KP L E G ++AK +G Y E S + Sbjct: 126 VPYVLIGTQIDLR----DDPKTLARLLYMKEKP---LTYEHGVKLAKAIGAQCYLECSAL 178 Query: 214 AQFGIKDVFDNAI 226 Q G+K VFD AI Sbjct: 179 TQKGLKAVFDEAI 191 >gi|229577148 ras homolog gene family, member V [Homo sapiens] Length = 236 Score = 102 bits (253), Expect = 2e-21 Identities = 71/203 (34%), Positives = 103/203 (50%), Gaps = 23/203 (11%) Query: 37 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 96 IKCV+VGD AVGK+ LI + CN +Y+ PT A+D + V + +VD Sbjct: 32 IKCVLVGDGAVGKSSLIVSYTCNGYPARYR------PT--ALDTFSV--------QVLVD 75 Query: 97 DVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154 V + LWDT G DR Y +DV + CFS+ P+S ++ W PEI+ P+ Sbjct: 76 GAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQ 135 Query: 155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 214 APV+LVG Q DLR + VN L + + + P+ K Y E S + Sbjct: 136 APVLLVGTQADLR----DDVN-VLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALT 190 Query: 215 QFGIKDVFDNAIRAALISRRHLQ 237 Q +K+VFD+AI +A+ + L+ Sbjct: 191 QKNLKEVFDSAILSAIEHKARLE 213 >gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] Length = 611 Score = 100 bits (249), Expect = 5e-21 Identities = 74/267 (27%), Positives = 130/267 (48%), Gaps = 25/267 (9%) Query: 451 VLKYLYTG-----ELDENER----DLMHIAHIAELLEVFDLRMMVANILNNEAFMNQEIT 501 +L+++Y+G EL+E+ R D ++++ E ++ N L N Sbjct: 343 ILRFIYSGAFQWEELEEDIRKKLKDSGDVSNVIEKVKCILKTPGKINCLRN--------C 394 Query: 502 KAFHVRR-----TNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFV 556 K + R+ +K L K +DV F + T+ AH+ +L++ C+ MAAMF G ++ Sbjct: 395 KTYQARKPLWFYNTSLKFFLNKPMLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYM 454 Query: 557 ESSTREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYT 616 E+ + + SK + LEYLYT + M L+I A + L + E + Sbjct: 455 EAKSVLIPVYGVSKETFLSFLEYLYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFI 514 Query: 617 VTGLME-ATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAM 675 +T L ++ + ++ D++ L+ A+FH + L+ W LH I TNY +K + + + Sbjct: 515 ITQLQSMPSRELASMNLDIVDLLKKAKFHHSDCLSTWLLHFIATNYLIFSQK--PEFQDL 572 Query: 676 SPENQEYFEKHRWPPVWYLKEEDHYQR 702 S E + + EKHRWP YLK+ Y++ Sbjct: 573 SVEERSFVEKHRWPSNMYLKQLAEYRK 599 Score = 44.7 bits (104), Expect = 3e-04 Identities = 55/227 (24%), Positives = 87/227 (38%), Gaps = 28/227 (12%) Query: 104 LWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQ 163 +WD F R G +D++V+ +++ + S H VK + P IK PVI+ Sbjct: 75 VWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIKRALNSVPVII---- 130 Query: 164 LDLRYADLEAVNRARRPLARPIKPNE---ILPPEKGREVAKELGIPYYETSVVAQFGIKD 220 A + P P+ ++ + +G ++AKELG Y E + F I Sbjct: 131 -----AAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDFYIGK 185 Query: 221 VFDNAIR----AALISRRHLQFWKSHLRN----VQRPLLQAPFLPPKPPPPIIVVPDPPS 272 F + AL + + K + N ++ P L+ P P V+ S Sbjct: 186 YFGGVLEYFMIQALNQKTSEKMKKRKMSNSFHGIRPPQLEQPEKMP-------VLKAEAS 238 Query: 273 SSEECPAHLLEDPLCADVILVLQERVRIF-AHKIYLSTSSSKFYDLF 318 +LL C DV+ ++ AHKI L S F LF Sbjct: 239 HYNSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLLF 285 >gi|4885581 Rho family GTPase 2 [Homo sapiens] Length = 227 Score = 92.4 bits (228), Expect = 1e-18 Identities = 73/211 (34%), Positives = 106/211 (50%), Gaps = 28/211 (13%) Query: 38 KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97 K VVVGD GKT L+ A +A Y VPTV+ + Y E+ +R Sbjct: 9 KIVVVGDAECGKTALLQVFAKDAYPGSY------VPTVF--ENYTASFEIDKRR------ 54 Query: 98 VSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155 + L +WDT G + D R AY SD V++CF I+ P +L V W E + FCP A Sbjct: 55 --IELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNA 112 Query: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYE-TSVV 213 V+LVGC+LD+R DL + + P+ E+G +AK++G + Y E +S Sbjct: 113 KVVLVGCKLDMR-TDLATLRELSKQRLIPV------THEQGTVLAKQVGAVSYVECSSRS 165 Query: 214 AQFGIKDVFDNAIRAALISRRHLQFWKSHLR 244 ++ ++DVF A A+L R H Q ++ R Sbjct: 166 SERSVRDVFHVATVASL-GRGHRQLRRTDSR 195 >gi|7657514 GTP-binding protein RHO6 [Homo sapiens] Length = 232 Score = 88.6 bits (218), Expect = 2e-17 Identities = 73/230 (31%), Positives = 104/230 (45%), Gaps = 32/230 (13%) Query: 31 RPNVETIKCVVVGDNAVGKTRL--ICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVL 88 +P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E Sbjct: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLETE 57 Query: 89 ERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLHHVKTMWYP 146 E+ V L LWDT G + D R Y SD V+LCF I+ P ++ W Sbjct: 58 EQR--------VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109 Query: 147 EIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP 206 EI +CP V+L+GC+ DLR DL + PI E+G +AK+LG Sbjct: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPIS------YEQGCAIAKQLGAE 162 Query: 207 YY--ETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAP 254 Y ++ ++ I +F A L L KS +R++ + LL P Sbjct: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211 >gi|4885069 ras homolog gene family, member E [Homo sapiens] Length = 244 Score = 84.7 bits (208), Expect = 3e-16 Identities = 73/225 (32%), Positives = 108/225 (48%), Gaps = 40/225 (17%) Query: 12 QKTSSDSMSRLMDSDMDYERPNVETIKC--VVVGDNAVGKTRLICARACNATLTQYQLLA 69 QK SS S +MD PN + +KC VVVGD+ GKT L+ A + Y Sbjct: 8 QKLSSKS---IMD-------PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY---- 52 Query: 70 THVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVL 127 VPTV+ + Y E+ D + L LWDT G + D R +Y SD V++ Sbjct: 53 --VPTVF--ENYTASFEI--------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLI 100 Query: 128 CFSIANPNSLHHVKTMWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKP 187 CF I+ P +L V W EI+ FCP ++LVGC+ DLR D+ + P+ Sbjct: 101 CFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVS- 158 Query: 188 NEILPPEKGREVAKELG-IPYYETSVV-AQFGIKDVFDNAIRAAL 230 ++G +AK++G Y E S + ++ ++D+F A A + Sbjct: 159 -----YDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV 198 >gi|4757770 ras homolog gene family, member H [Homo sapiens] Length = 191 Score = 84.0 bits (206), Expect = 5e-16 Identities = 62/204 (30%), Positives = 101/204 (49%), Gaps = 33/204 (16%) Query: 34 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 93 + +IKCV+VGD+AVGKT L+ T + PTV+ V Sbjct: 2 LSSIKCVLVGDSAVGKTSLL------VRFTSETFPEAYKPTVYENTGVDV---------- 45 Query: 94 VVDDVSVSLRLWDTFGDH--HKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHF 151 +D + +SL LWDT G+ R +Y ++DVV++C+S+AN NS ++K W EI+ Sbjct: 46 FMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSN 105 Query: 152 CPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIP-YYET 210 P PV++V Q D R +RA + +G+++A+++ Y E Sbjct: 106 LPCTPVLVVATQTDQREM---GPHRA-----------SCVNAMEGKKLAQDVRAKGYLEC 151 Query: 211 SVVAQFGIKDVFDNAIRAALISRR 234 S ++ G++ VF+ A+R A+ R Sbjct: 152 SALSNRGVQQVFECAVRTAVNQAR 175 >gi|38016957 ras homolog gene family, member F [Homo sapiens] Length = 211 Score = 83.6 bits (205), Expect = 6e-16 Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 26/209 (12%) Query: 32 PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 91 P + +K V+VGD GKT L+ + + Y P+V+ ++Y V + Sbjct: 15 PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66 Query: 92 RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 149 V+L L+DT G D+ + R +Y + +V++C+ + NP S +V W+PE+ Sbjct: 67 --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118 Query: 150 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYY 208 HFC P++L+GC+ DLR D E + + R PI + G +++ Y Sbjct: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITYMQ------GLSACEQIRAALYL 171 Query: 209 ETSVVAQFGIKDVFDNAIRAALISRRHLQ 237 E S + ++DVF A + AL + + Q Sbjct: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200 >gi|5803163 RAB40B, member RAS oncogene family [Homo sapiens] Length = 278 Score = 55.5 bits (132), Expect = 2e-07 Identities = 55/206 (26%), Positives = 86/206 (41%), Gaps = 37/206 (17%) Query: 37 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 96 +K ++VGD+ VGK ++ + A + Y A ID Y+ +L+ R Sbjct: 15 LKFLLVGDSDVGKGEILASLQDGAAESPYGHPA-------GID-YKTTTILLDGRR---- 62 Query: 97 DVSVSLRLWDTFGDHHKDRRF-AYGR-SDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154 V L+LWDT G F +Y R + V+L + IAN S + W EI P Sbjct: 63 ---VKLQLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFDGIDR-WIKEIDEHAPG 118 Query: 155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 214 P ILVG +L L + +P E+ + A+ LG+ ++E S + Sbjct: 119 VPKILVGNRLHLAF-------------------KRQVPTEQAQAYAERLGVTFFEVSPLC 159 Query: 215 QFGIKDVFDNAIRAALISRRHLQFWK 240 F I + F R L+ + W+ Sbjct: 160 NFNITESFTELARIVLLRHGMDRLWR 185 >gi|56550077 RAB40A, member RAS oncogene family [Homo sapiens] Length = 277 Score = 55.5 bits (132), Expect = 2e-07 Identities = 56/205 (27%), Positives = 87/205 (42%), Gaps = 39/205 (19%) Query: 37 IKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 96 +K ++VGD VGK+ ++ + A + Y L ID Y+ +L+ R Sbjct: 15 LKFLLVGDRDVGKSEILESLQDGAAESPYSHLG-------GID-YKTTTILLDGQR---- 62 Query: 97 DVSVSLRLWDTFGDHHKDRRF-AYGR-SDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPR 154 V L+LWDT G F +Y R + V+L + IAN S + W +I+ P Sbjct: 63 ---VKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDR-WIKKIEEHAPG 118 Query: 155 APVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELGIPYYETSVVA 214 P ILVG +L L + +P E+ + A+ LG+ ++E S + Sbjct: 119 VPKILVGNRLHLAF-------------------KRQVPREQAQAYAERLGVTFFEVSPLC 159 Query: 215 QFGIKDVFDNAIRAALISRRHLQFW 239 F I + F R L+ RH W Sbjct: 160 NFNIIESFTELARIVLL--RHRMNW 182 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.136 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,976,085 Number of Sequences: 37866 Number of extensions: 1550174 Number of successful extensions: 14006 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 212 Number of HSP's successfully gapped in prelim test: 189 Number of HSP's that attempted gapping in prelim test: 11527 Number of HSP's gapped (non-prelim): 1514 length of query: 749 length of database: 18,247,518 effective HSP length: 110 effective length of query: 639 effective length of database: 14,082,258 effective search space: 8998562862 effective search space used: 8998562862 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.