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Search of human proteins with 236463969
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
(207 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens] 420 e-118
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens] 401 e-112
gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens] 380 e-106
gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens] 380 e-106
gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens] 380 e-106
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens] 380 e-106
gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens] 355 1e-98
gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens] 355 1e-98
gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens] 350 5e-97
gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens] 350 5e-97
gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens] 345 2e-95
gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens] 337 4e-93
gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens] 333 5e-92
gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens] 323 8e-89
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 315 2e-86
gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens] 160 7e-40
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens] 122 2e-28
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens] 122 2e-28
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens] 114 6e-26
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens] 114 6e-26
gi|236461846 neuregulin 1 isoform ndf43c [Homo sapiens] 112 2e-25
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 56 2e-08
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 56 2e-08
gi|110349719 titin isoform N2-A [Homo sapiens] 54 7e-08
gi|93102361 palladin [Homo sapiens] 54 1e-07
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 53 2e-07
gi|66730481 neuregulin 3 [Homo sapiens] 51 6e-07
gi|45594240 limbic system-associated membrane protein [Homo sapi... 51 8e-07
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 50 1e-06
gi|110349717 titin isoform novex-2 [Homo sapiens] 50 1e-06
>gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
Length = 207
Score = 420 bits (1079), Expect = e-118
Identities = 207/207 (100%), Positives = 207/207 (100%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPN 180
DSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPN
Sbjct: 121 DSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPN 180
Query: 181 EFTGDRCQNYVMASFYSTSTPFLSLPE 207
EFTGDRCQNYVMASFYSTSTPFLSLPE
Sbjct: 181 EFTGDRCQNYVMASFYSTSTPFLSLPE 207
>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
Length = 241
Score = 401 bits (1031), Expect = e-112
Identities = 206/241 (85%), Positives = 207/241 (85%), Gaps = 34/241 (14%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTPFLSLP 206
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTPFLSLP
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTPFLSLP 240
Query: 207 E 207
E
Sbjct: 241 E 241
>gi|236463556 neuregulin 1 isoform ndf43b [Homo sapiens]
Length = 459
Score = 380 bits (976), Expect = e-106
Identities = 195/230 (84%), Positives = 196/230 (85%), Gaps = 34/230 (14%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 196
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 230
>gi|236464528 neuregulin 1 isoform HRG-beta2b [Homo sapiens]
Length = 420
Score = 380 bits (976), Expect = e-106
Identities = 195/230 (84%), Positives = 196/230 (85%), Gaps = 34/230 (14%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 196
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 230
>gi|116006957 neuregulin 1 isoform HRG-beta2 [Homo sapiens]
Length = 637
Score = 380 bits (976), Expect = e-106
Identities = 195/230 (84%), Positives = 196/230 (85%), Gaps = 34/230 (14%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 196
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 230
>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
Length = 645
Score = 380 bits (976), Expect = e-106
Identities = 195/230 (84%), Positives = 196/230 (85%), Gaps = 34/230 (14%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 196
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 230
>gi|236464356 neuregulin 1 isoform HRG-gamma3 [Homo sapiens]
Length = 177
Score = 355 bits (912), Expect = 1e-98
Identities = 177/177 (100%), Positives = 177/177 (100%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 177
DSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 121 DSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 177
>gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]
Length = 422
Score = 355 bits (912), Expect = 1e-98
Identities = 177/186 (95%), Positives = 178/186 (95%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
KK S + ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN
Sbjct: 237 KKEVSRVLCKRCALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 296
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTG 141
KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTG
Sbjct: 297 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTG 356
Query: 142 TSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTP 201
TSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTP
Sbjct: 357 TSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYSTSTP 416
Query: 202 FLSLPE 207
FLSLPE
Sbjct: 417 FLSLPE 422
>gi|7669526 neuregulin 1 isoform HRG-alpha [Homo sapiens]
Length = 640
Score = 350 bits (898), Expect = 5e-97
Identities = 183/225 (81%), Positives = 184/225 (81%), Gaps = 34/225 (15%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYV 191
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKC FTG RC V
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENV 225
>gi|7669520 neuregulin 1 isoform ndf43 [Homo sapiens]
Length = 462
Score = 350 bits (898), Expect = 5e-97
Identities = 183/225 (81%), Positives = 184/225 (81%), Gaps = 34/225 (15%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYV 191
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKC FTG RC V
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGARCTENV 225
>gi|236462984 neuregulin 1 isoform HRG-gamma2 [Homo sapiens]
Length = 194
Score = 345 bits (884), Expect = 2e-95
Identities = 177/194 (91%), Positives = 177/194 (91%), Gaps = 17/194 (8%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN-----------------ATSTSTTGTSHLVKCAEKEKTFCVNGGECF 163
DSASANITIVESN ATSTSTTGTSHLVKCAEKEKTFCVNGGECF
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSATSTSTTGTSHLVKCAEKEKTFCVNGGECF 180
Query: 164 MVKDLSNPSRYLCK 177
MVKDLSNPSRYLCK
Sbjct: 181 MVKDLSNPSRYLCK 194
>gi|116006965 neuregulin 1 isoform HRG-gamma [Homo sapiens]
Length = 211
Score = 337 bits (864), Expect = 4e-93
Identities = 176/211 (83%), Positives = 177/211 (83%), Gaps = 34/211 (16%)
Query: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS
Sbjct: 1 MSERKEGRGKGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETS 60
Query: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN
Sbjct: 61 SEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGN 120
Query: 121 DSASANITIVESN----------------------------------ATSTSTTGTSHLV 146
DSASANITIVESN +TSTSTTGTSHLV
Sbjct: 121 DSASANITIVESNEIITGMPASTEGAYVSSESPIRISVSTEGANTSSSTSTSTTGTSHLV 180
Query: 147 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 177
KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK
Sbjct: 181 KCAEKEKTFCVNGGECFMVKDLSNPSRYLCK 211
>gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]
Length = 590
Score = 333 bits (855), Expect = 5e-92
Identities = 163/163 (100%), Positives = 163/163 (100%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
Sbjct: 13 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 72
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEK 153
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEK
Sbjct: 73 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEK 132
Query: 154 TFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 196
TFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY
Sbjct: 133 TFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 175
>gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]
Length = 607
Score = 323 bits (827), Expect = 8e-89
Identities = 163/180 (90%), Positives = 163/180 (90%), Gaps = 17/180 (9%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
Sbjct: 13 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 72
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN-----------------ATS 136
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN ATS
Sbjct: 73 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSATS 132
Query: 137 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 196
TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY
Sbjct: 133 TSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFY 192
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 315 bits (807), Expect = 2e-86
Identities = 162/197 (82%), Positives = 163/197 (82%), Gaps = 34/197 (17%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG
Sbjct: 13 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 72
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN-------------------- 133
KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESN
Sbjct: 73 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNEIITGMPASTEGAYVSSESP 132
Query: 134 --------------ATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCP 179
+TSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCP
Sbjct: 133 IRISVSTEGANTSSSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCP 192
Query: 180 NEFTGDRCQNYVMASFY 196
NEFTGDRCQNYVMASFY
Sbjct: 193 NEFTGDRCQNYVMASFY 209
>gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens]
Length = 296
Score = 160 bits (405), Expect = 7e-40
Identities = 74/86 (86%), Positives = 77/86 (89%)
Query: 122 SASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNE 181
+ N+ +TSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNE
Sbjct: 211 TTETNLQTAPKLSTSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNE 270
Query: 182 FTGDRCQNYVMASFYSTSTPFLSLPE 207
FTGDRCQNYVMASFYSTSTPFLSLPE
Sbjct: 271 FTGDRCQNYVMASFYSTSTPFLSLPE 296
>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
Length = 844
Score = 122 bits (306), Expect = 2e-28
Identities = 69/187 (36%), Positives = 105/187 (56%), Gaps = 17/187 (9%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLY 327
Query: 129 IVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQ 188
+ + T +S +G H KC E K++CVNGG C+ ++ ++ S CKCP +TGDRCQ
Sbjct: 328 VNSVSTTLSSWSG--HARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPVGYTGDRCQ 382
Query: 189 NYVMASF 195
+ M +F
Sbjct: 383 QFAMVNF 389
>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
Length = 852
Score = 122 bits (306), Expect = 2e-28
Identities = 69/187 (36%), Positives = 105/187 (56%), Gaps = 17/187 (9%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLY 327
Query: 129 IVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQ 188
+ + T +S +G H KC E K++CVNGG C+ ++ ++ S CKCP +TGDRCQ
Sbjct: 328 VNSVSTTLSSWSG--HARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPVGYTGDRCQ 382
Query: 189 NYVMASF 195
+ M +F
Sbjct: 383 QFAMVNF 389
>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
Length = 858
Score = 114 bits (285), Expect = 6e-26
Identities = 66/179 (36%), Positives = 99/179 (55%), Gaps = 17/179 (9%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLY 327
Query: 129 IVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRC 187
+ + T +S +G H KC E K++CVNGG C+ ++ ++ S CKCPN F G RC
Sbjct: 328 VNSVSTTLSSWSG--HARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPNGFFGQRC 381
>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
Length = 850
Score = 114 bits (285), Expect = 6e-26
Identities = 66/179 (36%), Positives = 99/179 (55%), Gaps = 17/179 (9%)
Query: 11 GKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKW 70
GK KKE G + A P+LK+MKSQ G K L+CE ++ ++W
Sbjct: 218 GKNLKKEVGKILCTDCATR-------PKLKKMKSQTGQVGEKQSLKCEAAAGNPQPSYRW 270
Query: 71 FKNGNELNRKNKPQNIKIQKKPGK--SELRINKASLADSGEYMCKVISKLGNDSASANIT 128
FK+G ELNR ++I+I+ G+ S L+ NK + D+GEY+C+ + LG D+ +
Sbjct: 271 FKDGKELNRS---RDIRIKYGNGRKNSRLQFNKVKVEDAGEYVCEAENILGKDTVRGRLY 327
Query: 129 IVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGDRC 187
+ + T +S +G H KC E K++CVNGG C+ ++ ++ S CKCPN F G RC
Sbjct: 328 VNSVSTTLSSWSG--HARKCNETAKSYCVNGGVCYYIEGINQLS---CKCPNGFFGQRC 381
>gi|236461846 neuregulin 1 isoform ndf43c [Homo sapiens]
Length = 308
Score = 112 bits (280), Expect = 2e-25
Identities = 53/66 (80%), Positives = 56/66 (84%)
Query: 126 NITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCPNEFTGD 185
+I+I + ATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKC FTG
Sbjct: 6 HISIEDITATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLSNPSRYLCKCQPGFTGA 65
Query: 186 RCQNYV 191
RC V
Sbjct: 66 RCTENV 71
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 55.8 bits (133), Expect = 2e-08
Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E K G K L+CE S+ S F+W+K+ L K +K++ +P S
Sbjct: 222 PPYISEAKGTGVPVGQKGTLQCEASA-VPSAEFQWYKDDKRLIEGKK--GVKVENRPFLS 278
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKC 148
+L S D G Y C +KLG+ +AS I + A S + GTS C
Sbjct: 279 KLIFFNVSEHDYGNYTCVASNKLGHTNAS--IMLFGPGAVSEVSNGTSRRAGC 329
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 55.8 bits (133), Expect = 2e-08
Identities = 37/113 (32%), Positives = 53/113 (46%), Gaps = 5/113 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E K G K L+CE S+ S F+W+K+ L K +K++ +P S
Sbjct: 222 PPYISEAKGTGVPVGQKGTLQCEASA-VPSAEFQWYKDDKRLIEGKK--GVKVENRPFLS 278
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKC 148
+L S D G Y C +KLG+ +AS I + A S + GTS C
Sbjct: 279 KLIFFNVSEHDYGNYTCVASNKLGHTNAS--IMLFGPGAVSEVSNGTSRRAGC 329
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 54.3 bits (129), Expect = 7e-08
Identities = 50/186 (26%), Positives = 78/186 (41%), Gaps = 35/186 (18%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
A P ++++ E A G CE S ++RF+WFK G E+ +K I+
Sbjct: 3454 AAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIYESDK---CSIRSSKY 3509
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVE-------SNATSTST------- 139
S L I + + D GEY CK ++ G+ S +A +T+ E S S +T
Sbjct: 3510 ISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAK 3569
Query: 140 -----TGTSHLVKCAEKE-------KTFCVNGGECFMVKDLSN-----PSRYLCKCPNEF 182
TGT + +K+ + ++ E + +LSN Y CK N+F
Sbjct: 3570 FICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKF 3629
Query: 183 TGDRCQ 188
D CQ
Sbjct: 3630 GADICQ 3635
Score = 52.0 bits (123), Expect = 4e-07
Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 34/190 (17%)
Query: 35 LPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP K++ + GS + + C+ S + +WFK+G E++ K + + ++
Sbjct: 5235 IPPSFTKKLTKMDKVLGSSIHMECKVSGSLP-ISAQWFKDGKEISTSAKYRLVCHERSVS 5293
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVE----------SNATSTSTTGTS 143
L +N L D+ Y CKV + G+D+ S +T+ E A ST
Sbjct: 5294 ---LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFK 5350
Query: 144 HLVKCAE-------KEKTFCVNGGECFM------------VKDLSNPSRYLCKCPNEFTG 184
++K K+ V+G +CF+ D S +Y C N+
Sbjct: 5351 AILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGS 5410
Query: 185 DRCQNYVMAS 194
D C ++ +
Sbjct: 5411 DSCTTMLLVT 5420
Score = 46.6 bits (109), Expect = 1e-05
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 5/98 (5%)
Query: 35 LPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP K++K +S GS + L C + + + +WFK+ E++ K K
Sbjct: 4673 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHP-ISIQWFKDDQEISASEK---YKFSFHDN 4728
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+ L I++ DSG Y C +K G++ S ++T+ E
Sbjct: 4729 TAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE 4766
Score = 46.6 bits (109), Expect = 1e-05
Identities = 28/95 (29%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + + +SQ G ++ CE S E S +WFKN ++ + N+ I +
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISS---NVSISRSRNVY 33189
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIV 130
L I AS++DSG+Y K + G SA+A++ ++
Sbjct: 33190 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 33224
Score = 46.2 bits (108), Expect = 2e-05
Identities = 33/121 (27%), Positives = 57/121 (47%), Gaps = 5/121 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +KE++ +SA K+ L C+ + + W K+G +L ++ KI + +
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDED-RKVTVTWSKDGQKLP---PGKDYKICFEDKIA 3699
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTF 155
L I A L DSG Y+C ++ G+ S SA +T+ E + S+L+ E +
Sbjct: 3700 TLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP-PSFVKKVDPSYLMLPGESARLH 3758
Query: 156 C 156
C
Sbjct: 3759 C 3759
Score = 46.2 bits (108), Expect = 2e-05
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +++K +GS +V+ C+ + WF GNE++ K Q
Sbjct: 7682 PSFTRKLKETNGLSGSSVVMECKVYGS-PPISVSWFHEGNEISSGRKYQTTLTDNT---C 7737
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L +N +DSG+Y C + G+D SA +T+ E
Sbjct: 7738 ALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE 7773
Score = 45.8 bits (107), Expect = 3e-05
Identities = 42/186 (22%), Positives = 72/186 (38%), Gaps = 33/186 (17%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P ++E+K E S + L CE + W KN E+ K + +
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGT-PPFEVTWLKNNREIRSSKK---YTLTDRVSVF 5010
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANI----------------TIVESNATSTST 139
L I K +D+GEY C V ++ G+ S S + T+++S+AT ST
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQST 5070
Query: 140 TGTSHLVKCA---------EKEKTFC--VNGGECFMVKDLSN--PSRYLCKCPNEFTGDR 186
S + E + + V+ ++ + N RY C+ NE +R
Sbjct: 5071 VAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVER 5130
Query: 187 CQNYVM 192
C +++
Sbjct: 5131 CYAFLL 5136
Score = 45.1 bits (105), Expect = 4e-05
Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 5/131 (3%)
Query: 17 ERGSGKKPESAAGSQSPALPPRLKEMKSQESAA-GSKLVLRCETSSEYSSLRFKWFKNGN 75
E +G S + + + PP + S A GS ++L+CE S W K+
Sbjct: 6438 EAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGT-PPFEVVWVKDRK 6496
Query: 76 ELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNAT 135
++ K KI K + L I +D GEY CK +++G+D+ S ++ E
Sbjct: 6497 QVRNSKK---FKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRF 6553
Query: 136 STSTTGTSHLV 146
+ TS L+
Sbjct: 6554 VKKLSDTSTLI 6564
Score = 44.7 bits (104), Expect = 6e-05
Identities = 29/96 (30%), Positives = 53/96 (55%), Gaps = 6/96 (6%)
Query: 36 PPR-LKEMKSQESAA-GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
PP+ +K++++ + A G + L C+ S ++ WF+N +EL+ K I
Sbjct: 6363 PPKFVKKLEASKVAKQGESIQLECKISGS-PEIKVSWFRNDSELHESWKYNMSFINSV-- 6419
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L IN+AS DSG+Y+C+ + +G+ S S +T+
Sbjct: 6420 -ALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 6454
Score = 44.7 bits (104), Expect = 6e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
Query: 52 KLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYM 111
++ L+CE S + + KWFK+G E+ K I+ + L+I KA L D GEY+
Sbjct: 11679 EITLKCEVSKD---VPVKWFKDGEEIVPSPK---YSIKADGLRRILKIKKADLKDKGEYV 11732
Query: 112 CKVISKLGNDSASANITI 129
C G D AN+T+
Sbjct: 11733 C----DCGTDKTKANVTV 11746
Score = 44.3 bits (103), Expect = 7e-05
Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 9/89 (10%)
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
++ WFKN EL+ N +++ ++ L I + DSG Y C+ ++ +G+DS S
Sbjct: 3767 IQVTWFKNNKELSESN---TVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCST 3823
Query: 126 NITI------VESNATSTSTTGTSHLVKC 148
I I +++ + GT+ L++C
Sbjct: 3824 EIVIKEPPSFIKTLEPADIVRGTNALLQC 3852
Score = 43.9 bits (102), Expect = 1e-04
Identities = 26/110 (23%), Positives = 50/110 (45%), Gaps = 5/110 (4%)
Query: 31 QSPALPPRLKEMKSQESAA-GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQ 89
+ P PP + + + + G + L C +R +W K G E+ ++
Sbjct: 8340 KEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGS-EPIRIQWLKAGREIKPSDR---CSFS 8395
Query: 90 KKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTST 139
G + L + + ADSG+Y+CK + G+D+ + +TI + A + +T
Sbjct: 8396 FASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPAT 8445
Score = 43.1 bits (100), Expect = 2e-04
Identities = 37/177 (20%), Positives = 70/177 (39%), Gaps = 33/177 (18%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +++ +S L C+ + +R WFK+G E+ ++ +I G + L I
Sbjct: 4117 KPLRNVDSVVNGTCRLDCKIAGSLP-MRVSWFKDGKEIAASDR---YRIAFVEGTASLEI 4172
Query: 100 NKASLADSGEYMCKVISKLGNDSASANITIVE---------------SNATSTSTT--GT 142
+ + D+G + C+ + +G+ +S + + E +A +T G+
Sbjct: 4173 IRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGS 4232
Query: 143 SHLVKCAEKEKTFCVNGGECFMVKD------------LSNPSRYLCKCPNEFTGDRC 187
+ L K V+GG C++ K+ S+ Y CK N G C
Sbjct: 4233 TPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVEC 4289
Score = 42.7 bits (99), Expect = 2e-04
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 4/89 (4%)
Query: 44 SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKAS 103
SQ G L C+ + ++ WF N E+ +K + ++ + LR+
Sbjct: 4308 SQLLKKGDATQLACKVTGT-PPIKITWFANDREIKESSKHRMSFVEST---AVLRLTDVG 4363
Query: 104 LADSGEYMCKVISKLGNDSASANITIVES 132
+ DSGEYMC+ ++ G+D S+ + + ES
Sbjct: 4364 IEDSGEYMCEAQNEAGSDHCSSIVIVKES 4392
Score = 42.7 bits (99), Expect = 2e-04
Identities = 33/130 (25%), Positives = 57/130 (43%), Gaps = 8/130 (6%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
++ GS + PPR + S S K V T + WFK+ E+ R++
Sbjct: 7480 DTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRES--D 7537
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANI------TIVESNATSTS 138
NI I + L+ ++ A++G+Y C++ + G A + TIVE +
Sbjct: 7538 NIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKV 7597
Query: 139 TTGTSHLVKC 148
TTG + ++C
Sbjct: 7598 TTGDTCTLEC 7607
Score = 42.4 bits (98), Expect = 3e-04
Identities = 41/179 (22%), Positives = 68/179 (37%), Gaps = 34/179 (18%)
Query: 44 SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKAS 103
S++ GS + L+ T + L +WFK EL + I K+ +S L +
Sbjct: 4214 SKDVLPGSAVCLK-STFQGSTPLTIRWFKGNKELVSGG---SCYITKEALESSLELYLVK 4269
Query: 104 LADSGEYMCKVISKLGNDSASANITIVE------------------SNATSTSTTGTSHL 145
+DSG Y CKV + G SAN+ + E + + TGT +
Sbjct: 4270 TSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPI 4329
Query: 146 ----------VKCAEKEKTFCVNGGECFMVKD--LSNPSRYLCKCPNEFTGDRCQNYVM 192
+K + K + V + D + + Y+C+ NE D C + V+
Sbjct: 4330 KITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 4388
Score = 42.4 bits (98), Expect = 3e-04
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
+++ +S + G L C T + L KWFK+G EL NK + K G L+
Sbjct: 7589 VEKPESIKVTTGDTCTLEC-TVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSG---LK 7644
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNATSTST---------TGTSHLVKC 148
I + +DSG Y +V + +G DS +A++ + + + T +G+S +++C
Sbjct: 7645 IINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMEC 7703
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/102 (26%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 31 QSPALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQ 89
Q LPP +++K E G + L C + + ++ W+++G L +N++
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGS-APIQVCWYRDGVLLR---DDENLQTS 6224
Query: 90 KKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+ L+I + L+ SG+Y C + LG S+SA +T E
Sbjct: 6225 FVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE 6266
Score = 41.6 bits (96), Expect = 5e-04
Identities = 25/96 (26%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P ++++K + G+ +VL C S + + WF++GNE+ K Q+
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGS-APISVGWFQDGNEIVSGPKCQS---SFSENVC 6796
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L ++ +D+G Y C + G+D SA +T+ E
Sbjct: 6797 TLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE 6832
Score = 41.6 bits (96), Expect = 5e-04
Identities = 27/94 (28%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P ++ ++ E+ G L+C+ +R W+K +L ++ P K+Q K +
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGT-PEIRISWYKEHTKL--RSAPA-YKMQFKNNVA 7075
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITI 129
L INK +D GEY CK + +G ++SA + I
Sbjct: 7076 SLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 7109
Score = 41.2 bits (95), Expect = 6e-04
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 33 PALPPRLKE-MKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKK 91
P PP L +K+ G + L C S Y S W++ ++ + +I +
Sbjct: 939 PVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQIESSI---DFQITFQ 994
Query: 92 PGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEK 151
G + L I +A DSG + C +++ G S S + + S TT + K +
Sbjct: 995 SGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE--KFTTE 1052
Query: 152 EKTF 155
EK F
Sbjct: 1053 EKRF 1056
Score = 41.2 bits (95), Expect = 6e-04
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 9/117 (7%)
Query: 17 ERGSGKKPESAAGSQSPALPPR--LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNG 74
E SGK SA Q L P +K+++ + + G L+C+ + + W+K
Sbjct: 7943 ENASGKDSCSA---QILILEPPYFVKQLEPVKVSVGDSASLQCQLAGT-PEIGVSWYKGD 7998
Query: 75 NELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+L K+ + + L N+ + DSGEY+CK + +G SAS +T+ E
Sbjct: 7999 TKLRPTT---TYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE 8052
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/120 (24%), Positives = 56/120 (46%), Gaps = 10/120 (8%)
Query: 36 PPR-LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGK 94
PPR +K++ + G + LR + + W K+ E+ R++ +N +I
Sbjct: 6550 PPRFVKKLSDTSTLIGDAVELRAIVEG-FQPISVVWLKDRGEVIRES--ENTRISFIDNI 6606
Query: 95 SELRINKASLADSGEYMCKVISKLGNDSASANIT------IVESNATSTSTTGTSHLVKC 148
+ L++ ++SG+Y+C++ + G SA +T I+E T TTG ++C
Sbjct: 6607 ATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALEC 6666
Score = 40.4 bits (93), Expect = 0.001
Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 11/111 (9%)
Query: 26 SAAGSQSPALPPRLKEMK-------SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELN 78
+AAGS S + ++KE E+ G+ + L CE W+K+ EL
Sbjct: 7382 NAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGT-PPFHVSWYKDKRELR 7440
Query: 79 RKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
K KI + + + I AD GEY CK + +G+D+ +I +
Sbjct: 7441 SGKK---YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIAL 7488
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/105 (22%), Positives = 46/105 (43%), Gaps = 4/105 (3%)
Query: 46 ESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLA 105
++ G C + ++ W K+ E+ K Q ++ + L+++K
Sbjct: 8163 DAVVGESADFECHVTGT-QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKG--- 8218
Query: 106 DSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAE 150
DSG+Y C ++++G DS +A + I E + T S V+ E
Sbjct: 8219 DSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETE 8263
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/102 (24%), Positives = 50/102 (49%), Gaps = 6/102 (5%)
Query: 30 SQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQ 89
++ P +L+ K ++ S+L + S E +R WF+N +EL +K + I
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPE---IRVVWFRNEHELPASDKYRMTFID 5476
Query: 90 KKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+ +++N S DSG+++C+ + G+ S S + + E
Sbjct: 5477 SV---AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKE 5515
Score = 38.9 bits (89), Expect = 0.003
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 2/103 (1%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
E AG PA P + + Q+ G +V C+ + W K+G L +
Sbjct: 1071 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVY-WKKSGVPLTTGYR-Y 1128
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANI 127
+ K+ G+ +L I+ D+GEY V +K G SASA++
Sbjct: 1129 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 38.9 bits (89), Expect = 0.003
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT- 128
W K+G + + K K+ + G L I+K +DSG Y C V + G+ S+S +T
Sbjct: 32885 WTKDGKAITQGGK---YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 32941
Query: 129 --IVESNATSTSTTGTSHL 145
I ++ A ST TS +
Sbjct: 32942 KAIKDTEAQKVSTQKTSEI 32960
Score = 38.5 bits (88), Expect = 0.004
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KWFK+G EL +K KI S L+I DSGEY +V + +G S A I
Sbjct: 4611 KWFKDGQELTLGSK---YKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARIN 4667
Query: 129 IVE 131
+++
Sbjct: 4668 VLD 4670
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/99 (28%), Positives = 44/99 (44%), Gaps = 6/99 (6%)
Query: 33 PALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKP 92
P+ RL E + KL R S + W+KN E+ + N +I K
Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQP---ITVAWYKNNIEIQPTS---NCEITFKN 8302
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L++ KA + D+G Y CKV + G+ +++I I E
Sbjct: 8303 NTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 8341
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
CE S E + + KWFK+G E+ + K I K L INK L D EY C+V +
Sbjct: 12395 CELSRE--NAKVKWFKDGAEIKKGKK---YDIISKGAVRILVINKCLLDDEAEYSCEVRT 12449
Query: 117 KLGNDSASANITIVESNATST 137
S +T++E A T
Sbjct: 12450 A----RTSGMLTVLEEEAVFT 12466
Score = 38.1 bits (87), Expect = 0.005
Identities = 31/106 (29%), Positives = 47/106 (44%), Gaps = 4/106 (3%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
KE K E ++L E + WFK+ N + R + IQ L+I
Sbjct: 4397 KEFKPIEVLKEYDVMLLAEVAGT-PPFEITWFKD-NTILRSGRKYKTFIQDH--LVSLQI 4452
Query: 100 NKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHL 145
K AD+GEY C+V +++G+ SA +T+ E + TS L
Sbjct: 4453 LKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 4498
Score = 38.1 bits (87), Expect = 0.005
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 10/98 (10%)
Query: 34 ALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+ PP ++ +K+ E + L CE S W+K+ +L K KI K
Sbjct: 5521 SFPPIVETLKNAEVS------LECELSGT-PPFEVVWYKDKRQLRSSKK---YKIASKNF 5570
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
+ + I +D GEY CK +++G+D+ + + E
Sbjct: 5571 HTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE 5608
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + E++ E+A G + L+C+ + + W+K +L + +
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGT-PEITVSWYKGDTKLR---PTPEYRTYFTNNVA 6134
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L NK ++ DSGEY CK + +G S+ I E
Sbjct: 6135 TLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQE 6170
Score = 37.7 bits (86), Expect = 0.007
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 14/138 (10%)
Query: 23 KPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLR------FKWFKNGNE 76
K ++ GS + +LKE S S V+ E + +S+ +W K E
Sbjct: 5590 KAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649
Query: 77 LNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANI------TIV 130
+ R++ +NI+I + L+ KA A++G+Y+C++ + G A + IV
Sbjct: 5650 VIRES--ENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIV 5707
Query: 131 ESNATSTSTTGTSHLVKC 148
E T T G + ++C
Sbjct: 5708 EKAGPMTVTVGETCTLEC 5725
Score = 37.7 bits (86), Expect = 0.007
Identities = 18/70 (25%), Positives = 31/70 (44%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W+K+G ++ + + + G +L IN + D EY +K G DS A +T+
Sbjct: 31723 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Query: 130 VESNATSTST 139
+ ST
Sbjct: 31783 TLHPPPTDST 31792
Score = 37.4 bits (85), Expect = 0.009
Identities = 23/83 (27%), Positives = 34/83 (40%), Gaps = 4/83 (4%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSG 108
AG C + +R W K+ E+ N I LRI K DSG
Sbjct: 6284 AGESADFECHVTGA-QPMRITWSKDNKEIRPGG---NYTITCVGNTPHLRILKVGKGDSG 6339
Query: 109 EYMCKVISKLGNDSASANITIVE 131
+Y C+ + +G D SA +++ E
Sbjct: 6340 QYTCQATNDVGKDMCSAQLSVKE 6362
Score = 37.4 bits (85), Expect = 0.009
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK---WFKNGNELNRKNKPQNIKIQKKP 92
PP++ + E+ SK + + E S LR K W+K+G +L Q
Sbjct: 32717 PPKITQFLKAEA---SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFH--YSAD 32771
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSAS 124
G EL+IN + +D GEY+C++ + G +
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTN 32803
Score = 36.6 bits (83), Expect = 0.015
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 14 KKKERGSG--KKPESAAGS-QSPALPPR-LKEMK----SQESAAGSKLVLRCETSSEYSS 65
+K GSG K P+ A + Q A+P + +KE+K ++ GS + C S S+
Sbjct: 11089 RKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP--ST 11146
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
W K+G+ + K + I K +L I L+D+GEY C + +LGN ++
Sbjct: 11147 AITTWMKDGSNIRESPKHRFIADGKD---RKLHIIDVQLSDAGEYTC--VLRLGNKEKTS 11201
Query: 126 NITIV 130
+V
Sbjct: 11202 TAKLV 11206
Score = 35.4 bits (80), Expect = 0.034
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 4/80 (5%)
Query: 50 GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGE 109
G+ L C + L KWFK+G EL+ +K I K + L+I A ++D G
Sbjct: 6659 GNPFALECVVTGT-PELSAKWFKDGRELSADSKHHITFINK---VASLKIPCAEMSDKGL 6714
Query: 110 YMCKVISKLGNDSASANITI 129
Y +V + +G + + ++ +
Sbjct: 6715 YSFEVKNSVGKSNCTVSVHV 6734
Score = 35.4 bits (80), Expect = 0.034
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNK 82
K ++ Q G+ VL CE S E + + KWFKNG E+ + K
Sbjct: 12289 KPLEDQTVEEGATAVLECEVSRE--NAKVKWFKNGTEILKSKK 12329
Score = 35.0 bits (79), Expect = 0.045
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +K ++ + G+ +L+CE S WFK+ ++ R +K + QK
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGT-GPFEISWFKDKKQI-RSSKKYRLFSQKS--LV 3886
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L I + AD GEY C V +++G A + E
Sbjct: 3887 CLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE 3922
Score = 35.0 bits (79), Expect = 0.045
Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
+K + G L+L T + + W KNG + Q I + L
Sbjct: 7871 VKRLNDYSIEKGKPLILE-GTFTGTPPISVTWKKNGINVTPS---QRCNITTTEKSAILE 7926
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVE 131
I +++ D+G+Y C + + G DS SA I I+E
Sbjct: 7927 IPSSTVEDAGQYNCYIENASGKDSCSAQILILE 7959
Score = 34.3 bits (77), Expect = 0.077
Identities = 23/99 (23%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 34 ALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKP 92
A+PP + +K+ G+ +L C+ + S + WF ++ K Q
Sbjct: 5797 AVPPSFTRRLKNTGGVLGASCILECKVAGS-SPISVAWFHEKTKIVSGAKYQTTF---SD 5852
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L++N +D G Y C + G+D A +T+ E
Sbjct: 5853 NVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 5891
Score = 34.3 bits (77), Expect = 0.077
Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 5/117 (4%)
Query: 44 SQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKAS 103
S + A G +C + + ++ W K+ E+ N K+ + L + K
Sbjct: 7220 SVDLALGESGTFKCHVTGT-APIKITWAKDNREIRPGG---NYKMTLVENTATLTVLKVG 7275
Query: 104 LADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGG 160
D+G+Y C + G DS SA + + E S +VK E + C GG
Sbjct: 7276 KGDAGQYTCYASNIAGKDSCSAQLGVQEP-PRFIKKLEPSRIVKQDEFTRYECKIGG 7331
Score = 33.9 bits (76), Expect = 0.100
Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 7/103 (6%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K + Q A + V CE ++ S + +W ++G L N NI+ + K L I
Sbjct: 2624 KPLTDQTVAESQEAVFECEVANPDS--KGEWLRDGKHLPLTN---NIRSESDGHKRRLII 2678
Query: 100 NKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGT 142
L D GEY KV + SA + V+ T + T T
Sbjct: 2679 AATKLDDIGEYTYKVAT--SKTSAKLKVEAVKIKKTLKNLTVT 2719
Score = 33.9 bits (76), Expect = 0.100
Identities = 27/99 (27%), Positives = 41/99 (41%), Gaps = 5/99 (5%)
Query: 34 ALPPR-LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKP 92
A PP L KS + G C T + + W K+G L+ N +I
Sbjct: 3548 AYPPTFLSRPKSLTTFVGKAAKFIC-TVTGTPVIETIWQKDGAALSPS---PNWRISDAE 3603
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
K L ++ ++ D G Y CK +K G D A + I++
Sbjct: 3604 NKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIID 3642
Score = 33.5 bits (75), Expect = 0.13
Identities = 21/96 (21%), Positives = 46/96 (47%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +++ +SQ+ +++ L+ + + KWFK+ EL+ + K +
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGT-APMTIKWFKDNKELHSGAARS---VWKDDTST 4823
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L + A DSG Y+C++ + +G ++ A + + E
Sbjct: 4824 SLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE 4859
Score = 33.5 bits (75), Expect = 0.13
Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 5/121 (4%)
Query: 50 GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGE 109
G C+ + +R W+ +GNE+ K I G + +I+ A + +SG
Sbjct: 4876 GQSTTFECQITGT-PKIRVSWYLDGNEITAIQKHG---ISFIDGLATFQISGARVENSGT 4931
Query: 110 YMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLS 169
Y+C+ + G S S + + E T +VK ++ E V G F V L
Sbjct: 4932 YVCEARNDAGTASCSIELKVKEP-PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLK 4990
Query: 170 N 170
N
Sbjct: 4991 N 4991
Score = 33.5 bits (75), Expect = 0.13
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
C+ + S + W+ +L K +I + G + L + + D G Y CKV++
Sbjct: 31589 CKIENYDQSTQVTWYFGVRQLENSEK---YEITYEDGVAILYVKDITKLDDGTYRCKVVN 31645
Query: 117 KLGNDSASANITI 129
G DS+ A + +
Sbjct: 31646 DYGEDSSYAELFV 31658
Score = 33.1 bits (74), Expect = 0.17
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 25/101 (24%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E K + E + Y + +KW KNG E+ +K Q ++ K L
Sbjct: 2975 LKDINAEE-----KDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQ---MRTKKLTHSLN 3026
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNATSTST 139
I D+ +Y T V ATST+T
Sbjct: 3027 IRNVHFGDAADY-----------------TFVAGKATSTAT 3050
Score = 32.7 bits (73), Expect = 0.22
Identities = 15/66 (22%), Positives = 35/66 (53%), Gaps = 3/66 (4%)
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
++ W+K+ E+ +K ++ + L ++ S+ DSG+Y C+ + G+ S+S
Sbjct: 7335 IKVLWYKDETEIQESSK---FRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Query: 126 NITIVE 131
++ + E
Sbjct: 7392 SLKVKE 7397
Score = 32.7 bits (73), Expect = 0.22
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
++ ++ Q V C+ S E +++ KW++NG E+ K K +K L
Sbjct: 12826 VEHLEDQTVTEFDDAVFSCQLSREKANV--KWYRNGREIKEGKK---YKFEKDGSIHRLI 12880
Query: 99 INKASLADSGEYMCKV 114
I L D EY C V
Sbjct: 12881 IKDCRLDDECEYACGV 12896
Score = 32.7 bits (73), Expect = 0.22
Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G E+ ++ + ++ + L + K+ AD+G Y + +KLG+ +AS N+ +
Sbjct: 14420 WHKDGKEVKASDR---LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Query: 130 V 130
+
Sbjct: 14477 I 14477
Score = 32.0 bits (71), Expect = 0.38
Identities = 23/94 (24%), Positives = 39/94 (41%), Gaps = 4/94 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASAN 126
+ KWFK+ EL K I + S L + + +G+Y C V + +G+DS +
Sbjct: 5360 KIKWFKDDVELVSGPK---CFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTM 5416
Query: 127 ITIVESNATSTSTTGTSHLVKCAEKEKTFCVNGG 160
+ + E S +VK + + C G
Sbjct: 5417 LLVTEP-PKFVKKLEASKIVKAGDSSRLECKIAG 5449
Score = 31.2 bits (69), Expect = 0.65
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK+ + +E ++V CE ++E + KWF+N + +K I +K LR
Sbjct: 12646 LKDTRVKEQ---QEVVFNCEVNTE--GAKAKWFRNEEAIFDSSK---YIILQKDLVYTLR 12697
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVE 131
I A L D Y + + G + SA IVE
Sbjct: 12698 IRDAHLDDQANYNVSLTNHRGENVKSAANLIVE 12730
Score = 30.8 bits (68), Expect = 0.85
Identities = 20/93 (21%), Positives = 40/93 (43%), Gaps = 4/93 (4%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK + G ++L T + + W K+G + K + +K L
Sbjct: 5989 LKRLSDHSVEPGKSIILE-STYTGTLPISVTWKKDGFNITTSEKCNIVTTEKT---CILE 6044
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVE 131
I ++ D+G+Y C++ ++ G D A ++ +E
Sbjct: 6045 ILNSTKRDAGQYSCEIENEAGRDVCGALVSTLE 6077
Score = 30.8 bits (68), Expect = 0.85
Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASAN 126
+ KWFK EL ++ I + +EL + + +SG+Y C V + G+ S + +
Sbjct: 6864 KVKWFKGSRELV---PGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 6920
Query: 127 ITIVE 131
+ + E
Sbjct: 6921 LFVKE 6925
Score = 30.4 bits (67), Expect = 1.1
Identities = 43/193 (22%), Positives = 67/193 (34%), Gaps = 40/193 (20%)
Query: 50 GSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGE 109
G L C+ + L +W+K+G L K + K S LRI D+G
Sbjct: 5718 GETCTLECKVAGT-PELSVEWYKDGKLLTSSQKHKFSFYNKI---SSLRILSVERQDAGT 5773
Query: 110 YMCKVISKLGNDSASANITIVESNATSTST---------TGTSHLVKCAE---------- 150
Y +V + +G S +A + + + + T G S +++C
Sbjct: 5774 YTFQVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAW 5833
Query: 151 -KEKTFCVNGGE---------CFM---VKDLSNPSRYLCKCPNEFTGDRCQNYVMA---- 193
EKT V+G + C + D S+ Y C N D C+ +
Sbjct: 5834 FHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 5893
Query: 194 SFYSTSTPFLSLP 206
SF P LP
Sbjct: 5894 SFVKEPEPLEVLP 5906
Score = 30.4 bits (67), Expect = 1.1
Identities = 17/68 (25%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASAN 126
+ WF+ EL + ++ I + +EL + ++ SGEY C V + G S +
Sbjct: 5923 KVNWFRGARELVKGDR---CNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTR 5979
Query: 127 ITIVESNA 134
+ + E A
Sbjct: 5980 LFVKEPAA 5987
Score = 29.6 bits (65), Expect = 1.9
Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW K + + N+ + I +K +++L I + DSG Y C ++ G ++ N+
Sbjct: 8486 KWTKG--KWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 8543
Query: 129 IVE 131
+ E
Sbjct: 8544 VDE 8546
Score = 29.6 bits (65), Expect = 1.9
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+ + + P+ +KI + S+ + KA +D G+Y+ + G+ A A + +
Sbjct: 18235 WTKDKDATDLTRSPR-VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Query: 130 VE 131
++
Sbjct: 18294 LD 18295
Score = 29.6 bits (65), Expect = 1.9
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNI-KIQKKPGKSELRINKASLADS 107
AG +VL + + W K G ++ +P +I +I P S L I A+ D+
Sbjct: 20392 AGDTIVLNAISILGKPLPKSSWSKAGKDI----RPSDITQITSTPTSSMLTIKYATRKDA 20447
Query: 108 GEYMCKVISKLGNDSASANITIVE 131
GEY + G +T+++
Sbjct: 20448 GEYTITATNPFGTKVEHVKVTVLD 20471
Score = 29.6 bits (65), Expect = 1.9
Identities = 23/102 (22%), Positives = 37/102 (36%), Gaps = 4/102 (3%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
L + +S G C+T E W + G L+ + Q + KS
Sbjct: 32564 LTKPRSMTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLSTSARHQ---VTTTKYKSTFE 32619
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTT 140
I+ +D G Y V + G A +TI ++ T + T
Sbjct: 32620 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVT 32661
Score = 29.6 bits (65), Expect = 1.9
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 35 LPPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP+++ + S S G L + C + E + W G +++ + + + I+
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGRKIHSQEQGR-FHIENTDD 33384
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L I D G Y + ++ G+DSA+ NI I
Sbjct: 33385 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 29.3 bits (64), Expect = 2.5
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +K + + + CE S + +W K+ EL ++ IKIQK+ L I
Sbjct: 3062 KHIKDIKVLEKKRAMFECEVSEP--DITVQWMKDDQELQITDR---IKIQKEKYVHRLLI 3116
Query: 100 NKASLADSGEY 110
++D+G+Y
Sbjct: 3117 PSTRMSDAGKY 3127
Score = 29.3 bits (64), Expect = 2.5
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WFK +EL ++ + + +EL + + SGEY C V ++ G S + ++ I
Sbjct: 7808 WFKGSSELVPGDR---CNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI 7864
Score = 28.9 bits (63), Expect = 3.2
Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+W +G L N+ +++ + G L A DSG C+ +K G D SA +
Sbjct: 1737 EWLHDGKPLEAANR---LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1793
Query: 129 IVESNA 134
+ + +
Sbjct: 1794 VKDEKS 1799
Score = 28.5 bits (62), Expect = 4.2
Identities = 18/96 (18%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P +K+++S S G + + W K+ +E+ + NI++ + +
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLP-ITVTWLKDSDEITEDD---NIRMTFENNVA 4541
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVE 131
L ++ + G+Y+C+ + G SA +++ E
Sbjct: 4542 SLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKE 4577
Score = 28.5 bits (62), Expect = 4.2
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSP--ALPP----------RLKEMKSQESAAGSKLVLRC 57
KG + KE + E+AAG P A PP ++ S E G ++ L
Sbjct: 14642 KGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 14701
Query: 58 ETS-SEYSSLRFKWFKNGN-----ELNRKNKP--------------------QNIKIQK- 90
S S Y ++ W K+ N E+ ++ P Q + I
Sbjct: 14702 SISGSPYPTIT--WIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNS 14759
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
K G+S+LR+ + D G YM KV + G A ++++++
Sbjct: 14760 KKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT 14801
Score = 28.5 bits (62), Expect = 4.2
Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNI---KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSA 123
+ +W KN + + I ++ + K+EL I KA D G Y ++LG+
Sbjct: 15429 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 15488
Query: 124 SANITIVE 131
+ ++ + +
Sbjct: 15489 NVHVEVYD 15496
Score = 28.5 bits (62), Expect = 4.2
Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
++ E ++ LPP++ + AG KL + + KW K +E+ +
Sbjct: 18885 REAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPT-CKWKKGEDEVVTSS 18943
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
++ + K S L I + DSG Y + G D+ + ++++
Sbjct: 18944 ---HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 18991
Score = 28.5 bits (62), Expect = 4.2
Identities = 14/68 (20%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF G++L + + ++ ++L I + ++ D+GEY ++ + G S + + I
Sbjct: 29772 WFFAGSKLRESER---VTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 29828
Query: 130 VESNATST 137
++ T
Sbjct: 29829 LDKPGPPT 29836
Score = 28.1 bits (61), Expect = 5.5
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF +G ++ N + + K+ G L I A+ +DSGE+ ++ G S S +T+
Sbjct: 1490 WFHDGQQI--VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1547
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW +G+E+ ++ ++ S L I D+GEY V + G+ + + ++T
Sbjct: 17543 KWTTDGSEIKTD---EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 17599
Query: 129 IVE 131
+++
Sbjct: 17600 VLD 17602
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W + E K ++I+K ++L I+ D+G+Y+ K+ + G+ SA + +
Sbjct: 24058 WSREEGEFTDK-----VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 24112
Query: 130 VES 132
+++
Sbjct: 24113 LDT 24115
Score = 27.7 bits (60), Expect = 7.2
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVI 115
CETS + ++ KW+K+G E++ +K + +K S L I+ +D+ +Y C ++
Sbjct: 2196 CETSEPF--VKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTID---TSDAEDYSCVLV 2249
Score = 27.7 bits (60), Expect = 7.2
Identities = 24/109 (22%), Positives = 48/109 (44%), Gaps = 9/109 (8%)
Query: 24 PESAAGSQS-PALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
PE + Q P PP + ++ ++ G +C S + L+ W+ ++K
Sbjct: 3331 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKVSWYSK----DKKI 3384
Query: 82 KPQNI-KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
KP ++ + +L I +A D G Y + +G S++AN+++
Sbjct: 3385 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 27.7 bits (60), Expect = 7.2
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K EL++ + I KSEL I A D G Y+ + G+ A+A + +
Sbjct: 15138 WTKEEGELDK----DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 15193
Query: 130 VE 131
+
Sbjct: 15194 FD 15195
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 53.5 bits (127), Expect = 1e-07
Identities = 40/123 (32%), Positives = 66/123 (53%), Gaps = 7/123 (5%)
Query: 18 RGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNEL 77
R S +P SA PA P +++++SQE A GS++ L C + + R +WF G EL
Sbjct: 255 RKSHPQPHSAL--HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGN-PTPRVRWFCEGKEL 311
Query: 78 NRKNKPQNIKIQKKPGK-SELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATS 136
+ N P +I+I + G L I +A D+G Y C + G+D+ SA + I +++T
Sbjct: 312 H--NTP-DIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTD 368
Query: 137 TST 139
+ +
Sbjct: 369 SDS 371
Score = 40.4 bits (93), Expect = 0.001
Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 11/118 (9%)
Query: 29 GSQSPALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIK 87
G+ + PP KE+++ A G +VL C L+ +WF+ G+E+ ++ P
Sbjct: 433 GTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGA-PPLQVQWFRQGSEI--QDSPDFRI 489
Query: 88 IQKKPGKSE-------LRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTS 138
+QKKP + L I + D+G + C + G+ +++A + + +N + S
Sbjct: 490 LQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCS 547
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 52.8 bits (125), Expect = 2e-07
Identities = 37/122 (30%), Positives = 55/122 (45%), Gaps = 12/122 (9%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E K G K L+CE S+ S F+W+K+ L K +K++ +P S
Sbjct: 222 PPYISEAKGTGVPVGQKGTLQCEASA-VPSAEFQWYKDDKRLIEGKK--GVKVENRPFLS 278
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIVES---------NATSTSTTGTSHLV 146
+L S D G Y C +KLG+ +AS + V++ A S + GTS
Sbjct: 279 KLIFFNVSEHDYGNYTCVASNKLGHTNASIMLFEVKTTALTPWKGPGAVSEVSNGTSRRA 338
Query: 147 KC 148
C
Sbjct: 339 GC 340
>gi|66730481 neuregulin 3 [Homo sapiens]
Length = 696
Score = 51.2 bits (121), Expect = 6e-07
Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 7/82 (8%)
Query: 116 SKLGNDSASANITIVESNA------TSTSTTGTSHLVKCAEKEKTFCVNGGECFMVKDLS 169
S + S+SA T E++ T+ ST + H C +K+ +C+N GECF+++ L+
Sbjct: 252 SSSSSSSSSATTTTPETSTSPKFHTTTYSTERSEHFKPCRDKDLAYCLNDGECFVIETLT 311
Query: 170 NPSRYLCKCPNEFTGDRCQNYV 191
++ C+C + G RC ++
Sbjct: 312 GSHKH-CRCKEGYQGVRCDQFL 332
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 50.8 bits (120), Expect = 8e-07
Identities = 27/89 (30%), Positives = 46/89 (51%), Gaps = 4/89 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E KS E+ G + L+CE S+ + F+W+++ +N N ++I+ G+S
Sbjct: 218 PPTITESKSNEATTGRQASLKCEASA-VPAPDFEWYRDDTRINSAN---GLEIKSTEGQS 273
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSAS 124
L + + G Y C +KLG +AS
Sbjct: 274 SLTVTNVTEEHYGNYTCVAANKLGVTNAS 302
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 50.4 bits (119), Expect = 1e-06
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 3/89 (3%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
PP + E K G K L+CE S+ S F+W+K+ L K +K++ +P S
Sbjct: 222 PPYISEAKGTGVPVGQKGTLQCEASA-VPSAEFQWYKDDKRLIEGKK--GVKVENRPFLS 278
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSAS 124
+L S D G Y C +KLG+ +AS
Sbjct: 279 KLIFFNVSEHDYGNYTCVASNKLGHTNAS 307
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 50.4 bits (119), Expect = 1e-06
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 5/111 (4%)
Query: 20 SGKKPESAAGSQSPALPPRLK-EMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELN 78
SGK SA + P +K +++ E A G CE S ++RF+WFK G E+
Sbjct: 4512 SGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSA-PNVRFQWFKAGREIY 4570
Query: 79 RKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+K I+ S L I + + D GEY CK ++ G+ S +A +T+
Sbjct: 4571 ESDK---CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 46.6 bits (109), Expect = 1e-05
Identities = 28/95 (29%), Positives = 48/95 (50%), Gaps = 4/95 (4%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKS 95
P + + +SQ G ++ CE S E S +WFKN ++ + N+ I +
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISS---NVSISRSRNVY 26884
Query: 96 ELRINKASLADSGEYMCKVISKLGNDSASANITIV 130
L I AS++DSG+Y K + G SA+A++ ++
Sbjct: 26885 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVL 26919
Score = 44.7 bits (104), Expect = 6e-05
Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 10/78 (12%)
Query: 52 KLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYM 111
++ L+CE S + + KWFK+G E+ K I+ + L+I KA L D GEY+
Sbjct: 5374 EITLKCEVSKD---VPVKWFKDGEEIVPSPK---YSIKADGLRRILKIKKADLKDKGEYV 5427
Query: 112 CKVISKLGNDSASANITI 129
C G D AN+T+
Sbjct: 5428 C----DCGTDKTKANVTV 5441
Score = 41.2 bits (95), Expect = 6e-04
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 33 PALPPRLKE-MKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKK 91
P PP L +K+ G + L C S Y S W++ ++ + +I +
Sbjct: 893 PVTPPTLVSGLKNVTVIEGESVTLECHISG-YPSPTVTWYREDYQIESSI---DFQITFQ 948
Query: 92 PGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGTSHLVKCAEK 151
G + L I +A DSG + C +++ G S S + + S TT + K +
Sbjct: 949 SGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTE--KFTTE 1006
Query: 152 EKTF 155
EK F
Sbjct: 1007 EKRF 1010
Score = 40.0 bits (92), Expect = 0.001
Identities = 32/130 (24%), Positives = 47/130 (36%), Gaps = 3/130 (2%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK 69
KG+G K +S P P LKE+K A G + E +
Sbjct: 3741 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPT-VT 3799
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WFK +L I G +N DSG Y+CK + LG + +A + +
Sbjct: 3800 WFKENKQLC--TSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Query: 130 VESNATSTST 139
+ + T T
Sbjct: 3858 LLEDTDMTDT 3867
Score = 38.9 bits (89), Expect = 0.003
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 2/103 (1%)
Query: 25 ESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQ 84
E AG PA P + + Q+ G +V C+ + W K+G L +
Sbjct: 1025 EEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVY-WKKSGVPLTTGYR-Y 1082
Query: 85 NIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANI 127
+ K+ G+ +L I+ D+GEY V +K G SASA++
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 38.9 bits (89), Expect = 0.003
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 6/79 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT- 128
W K+G + + K K+ + G L I+K +DSG Y C V + G+ S+S +T
Sbjct: 26580 WTKDGKAITQGGK---YKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTI 26636
Query: 129 --IVESNATSTSTTGTSHL 145
I ++ A ST TS +
Sbjct: 26637 KAIKDTEAQKVSTQKTSEI 26655
Score = 38.5 bits (88), Expect = 0.004
Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
CE S E + + KWFK+G E+ + K I K L INK L D EY C+V +
Sbjct: 6090 CELSRE--NAKVKWFKDGAEIKKGKK---YDIISKGAVRILVINKCLLDDEAEYSCEVRT 6144
Query: 117 KLGNDSASANITIVESNATST 137
S +T++E A T
Sbjct: 6145 A----RTSGMLTVLEEEAVFT 6161
Score = 37.7 bits (86), Expect = 0.007
Identities = 18/70 (25%), Positives = 31/70 (44%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W+K+G ++ + + + G +L IN + D EY +K G DS A +T+
Sbjct: 25418 WYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Query: 130 VESNATSTST 139
+ ST
Sbjct: 25478 TLHPPPTDST 25487
Score = 37.4 bits (85), Expect = 0.009
Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 8/92 (8%)
Query: 36 PPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFK---WFKNGNELNRKNKPQNIKIQKKP 92
PP++ + E+ SK + + E S LR K W+K+G +L Q
Sbjct: 26412 PPKITQFLKAEA---SKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFH--YSAD 26466
Query: 93 GKSELRINKASLADSGEYMCKVISKLGNDSAS 124
G EL+IN + +D GEY+C++ + G +
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTN 26498
Score = 36.6 bits (83), Expect = 0.015
Identities = 36/125 (28%), Positives = 59/125 (47%), Gaps = 15/125 (12%)
Query: 14 KKKERGSG--KKPESAAGS-QSPALPPR-LKEMK----SQESAAGSKLVLRCETSSEYSS 65
+K GSG K P+ A + Q A+P + +KE+K ++ GS + C S S+
Sbjct: 4784 RKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVSP--ST 4841
Query: 66 LRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASA 125
W K+G+ + K + I K +L I L+D+GEY C + +LGN ++
Sbjct: 4842 AITTWMKDGSNIRESPKHRFIADGKD---RKLHIIDVQLSDAGEYTC--VLRLGNKEKTS 4896
Query: 126 NITIV 130
+V
Sbjct: 4897 TAKLV 4901
Score = 35.4 bits (80), Expect = 0.034
Identities = 17/43 (39%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNK 82
K ++ Q G+ VL CE S E + + KWFKNG E+ + K
Sbjct: 5984 KPLEDQTVEEGATAVLECEVSRE--NAKVKWFKNGTEILKSKK 6024
Score = 33.9 bits (76), Expect = 0.100
Identities = 29/103 (28%), Positives = 43/103 (41%), Gaps = 7/103 (6%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K + Q A + V CE ++ S + +W ++G L N NI+ + K L I
Sbjct: 2578 KPLTDQTVAESQEAVFECEVANPDS--KGEWLRDGKHLPLTN---NIRSESDGHKRRLII 2632
Query: 100 NKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTTGT 142
L D GEY KV + SA + V+ T + T T
Sbjct: 2633 AATKLDDIGEYTYKVAT--SKTSAKLKVEAVKIKKTLKNLTVT 2673
Score = 33.5 bits (75), Expect = 0.13
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVIS 116
C+ + S + W+ +L K +I + G + L + + D G Y CKV++
Sbjct: 25284 CKIENYDQSTQVTWYFGVRQLENSEK---YEITYEDGVAILYVKDITKLDDGTYRCKVVN 25340
Query: 117 KLGNDSASANITI 129
G DS+ A + +
Sbjct: 25341 DYGEDSSYAELFV 25353
Score = 33.1 bits (74), Expect = 0.17
Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 25/101 (24%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK++ ++E K + E + Y + +KW KNG E+ +K Q ++ K L
Sbjct: 2929 LKDINAEE-----KDTITFEVTVNYEGISYKWLKNGVEIKSTDKCQ---MRTKKLTHSLN 2980
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNATSTST 139
I D+ +Y T V ATST+T
Sbjct: 2981 IRNVHFGDAADY-----------------TFVAGKATSTAT 3004
Score = 32.7 bits (73), Expect = 0.22
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 5/76 (6%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
++ ++ Q V C+ S E +++ KW++NG E+ K K +K L
Sbjct: 6521 VEHLEDQTVTEFDDAVFSCQLSREKANV--KWYRNGREIKEGKK---YKFEKDGSIHRLI 6575
Query: 99 INKASLADSGEYMCKV 114
I L D EY C V
Sbjct: 6576 IKDCRLDDECEYACGV 6591
Score = 32.7 bits (73), Expect = 0.22
Identities = 16/61 (26%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+G E+ ++ + ++ + L + K+ AD+G Y + +KLG+ +AS N+ +
Sbjct: 8115 WHKDGKEVKASDR---LTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Query: 130 V 130
+
Sbjct: 8172 I 8172
Score = 31.2 bits (69), Expect = 0.65
Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
LK+ + +E ++V CE ++E + KWF+N + +K I +K LR
Sbjct: 6341 LKDTRVKEQ---QEVVFNCEVNTE--GAKAKWFRNEEAIFDSSK---YIILQKDLVYTLR 6392
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVE 131
I A L D Y + + G + SA IVE
Sbjct: 6393 IRDAHLDDQANYNVSLTNHRGENVKSAANLIVE 6425
Score = 29.6 bits (65), Expect = 1.9
Identities = 14/62 (22%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K+ + + P+ +KI + S+ + KA +D G+Y+ + G+ A A + +
Sbjct: 11930 WTKDKDATDLTRSPR-VKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Query: 130 VE 131
++
Sbjct: 11989 LD 11990
Score = 29.6 bits (65), Expect = 1.9
Identities = 21/84 (25%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 49 AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNI-KIQKKPGKSELRINKASLADS 107
AG +VL + + W K G ++ +P +I +I P S L I A+ D+
Sbjct: 14087 AGDTIVLNAISILGKPLPKSSWSKAGKDI----RPSDITQITSTPTSSMLTIKYATRKDA 14142
Query: 108 GEYMCKVISKLGNDSASANITIVE 131
GEY + G +T+++
Sbjct: 14143 GEYTITATNPFGTKVEHVKVTVLD 14166
Score = 29.6 bits (65), Expect = 1.9
Identities = 23/102 (22%), Positives = 37/102 (36%), Gaps = 4/102 (3%)
Query: 39 LKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELR 98
L + +S G C+T E W + G L+ + Q + KS
Sbjct: 26259 LTKPRSMTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLSTSARHQ---VTTTKYKSTFE 26314
Query: 99 INKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTT 140
I+ +D G Y V + G A +TI ++ T + T
Sbjct: 26315 ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVT 26356
Score = 29.6 bits (65), Expect = 1.9
Identities = 23/96 (23%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 35 LPPRLKEMKSQESA-AGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPG 93
+PP+++ + S S G L + C + E + W G +++ + + + I+
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGRKIHSQEQGR-FHIENTDD 27079
Query: 94 KSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
+ L I D G Y + ++ G+DSA+ NI I
Sbjct: 27080 LTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 29.3 bits (64), Expect = 2.5
Identities = 19/71 (26%), Positives = 33/71 (46%), Gaps = 5/71 (7%)
Query: 40 KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRI 99
K +K + + + CE S + +W K+ EL ++ IKIQK+ L I
Sbjct: 3016 KHIKDIKVLEKKRAMFECEVSEP--DITVQWMKDDQELQITDR---IKIQKEKYVHRLLI 3070
Query: 100 NKASLADSGEY 110
++D+G+Y
Sbjct: 3071 PSTRMSDAGKY 3081
Score = 28.9 bits (63), Expect = 3.2
Identities = 16/66 (24%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
+W +G L N+ +++ + G L A DSG C+ +K G D SA +
Sbjct: 1691 EWLHDGKPLEAANR---LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLI 1747
Query: 129 IVESNA 134
+ + +
Sbjct: 1748 VKDEKS 1753
Score = 28.9 bits (63), Expect = 3.2
Identities = 14/39 (35%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 97 LRINKASLAD-SGEYMCKVISKLGNDSASANITIVESNA 134
L I+K + D GEY+C+ ++ G + SA +T+V+ A
Sbjct: 4490 LVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAA 4528
Score = 28.5 bits (62), Expect = 4.2
Identities = 39/162 (24%), Positives = 64/162 (39%), Gaps = 41/162 (25%)
Query: 10 KGKGKKKERGSGKKPESAAGSQSP--ALPP----------RLKEMKSQESAAGSKLVLRC 57
KG + KE + E+AAG P A PP ++ S E G ++ L
Sbjct: 8337 KGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDA 8396
Query: 58 ETS-SEYSSLRFKWFKNGN-----ELNRKNKP--------------------QNIKIQK- 90
S S Y ++ W K+ N E+ ++ P Q + I
Sbjct: 8397 SISGSPYPTIT--WIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNS 8454
Query: 91 KPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
K G+S+LR+ + D G YM KV + G A ++++++
Sbjct: 8455 KKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDT 8496
Score = 28.5 bits (62), Expect = 4.2
Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 67 RFKWFKNGNELNRKNKPQNI---KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSA 123
+ +W KN + + I ++ + K+EL I KA D G Y ++LG+
Sbjct: 9124 KIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFR 9183
Query: 124 SANITIVE 131
+ ++ + +
Sbjct: 9184 NVHVEVYD 9191
Score = 28.5 bits (62), Expect = 4.2
Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 22 KKPESAAGSQSPALPPRLKEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
++ E ++ LPP++ + AG KL + + KW K +E+ +
Sbjct: 12580 REAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPT-CKWKKGEDEVVTSS 12638
Query: 82 KPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVES 132
++ + K S L I + DSG Y + G D+ + ++++
Sbjct: 12639 ---HLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDA 12686
Score = 28.5 bits (62), Expect = 4.2
Identities = 14/68 (20%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF G++L + + ++ ++L I + ++ D+GEY ++ + G S + + I
Sbjct: 23467 WFFAGSKLRESER---VTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVII 23523
Query: 130 VESNATST 137
++ T
Sbjct: 23524 LDKPGPPT 23531
Score = 28.1 bits (61), Expect = 5.5
Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
WF +G ++ N + + K+ G L I A+ +DSGE+ ++ G S S +T+
Sbjct: 1444 WFHDGQQI--VNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTV 1501
Score = 28.1 bits (61), Expect = 5.5
Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 10/121 (8%)
Query: 24 PESAAGSQS-PALPPRL-KEMKSQESAAGSKLVLRCETSSEYSSLRFKWFKNGNELNRKN 81
PE + Q P PP + ++ ++ G +C S + L+ W+ ++K
Sbjct: 3285 PEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKVSWYSK----DKKI 3338
Query: 82 KPQNI-KIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITIVESNATSTSTT 140
KP ++ + +L I +A D G Y + +G S++AN+++ E A ++
Sbjct: 3339 KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL-EVQALDRQSS 3397
Query: 141 G 141
G
Sbjct: 3398 G 3398
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/63 (22%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 69 KWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANIT 128
KW +G+E+ ++ ++ S L I D+GEY V + G+ + + ++T
Sbjct: 11238 KWTTDGSEIKTD---EHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLT 11294
Query: 129 IVE 131
+++
Sbjct: 11295 VLD 11297
Score = 28.1 bits (61), Expect = 5.5
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 5/63 (7%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W + E K ++I+K ++L I+ D+G+Y+ K+ + G+ SA + +
Sbjct: 17753 WSREEGEFTDK-----VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17807
Query: 130 VES 132
+++
Sbjct: 17808 LDT 17810
Score = 27.7 bits (60), Expect = 7.2
Identities = 17/59 (28%), Positives = 33/59 (55%), Gaps = 5/59 (8%)
Query: 57 CETSSEYSSLRFKWFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVI 115
CETS + ++ KW+K+G E++ +K + +K S L I+ +D+ +Y C ++
Sbjct: 2150 CETSEPF--VKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTID---TSDAEDYSCVLV 2203
Score = 27.7 bits (60), Expect = 7.2
Identities = 17/62 (27%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Query: 70 WFKNGNELNRKNKPQNIKIQKKPGKSELRINKASLADSGEYMCKVISKLGNDSASANITI 129
W K EL++ + I KSEL I A D G Y+ + G+ A+A + +
Sbjct: 8833 WTKEEGELDK----DRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8888
Query: 130 VE 131
+
Sbjct: 8889 FD 8890
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,327,757
Number of Sequences: 37866
Number of extensions: 376851
Number of successful extensions: 3674
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 185
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 2419
Number of HSP's gapped (non-prelim): 1429
length of query: 207
length of database: 18,247,518
effective HSP length: 98
effective length of query: 109
effective length of database: 14,536,650
effective search space: 1584494850
effective search space used: 1584494850
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.