BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] (406 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 870 0.0 gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 120 2e-27 gi|160707881 formin 2 [Homo sapiens] 116 3e-26 gi|14249119 Rhox homeobox family, member 2 [Homo sapiens] 116 3e-26 gi|153791494 Rhox homeobox family, member 2B [Homo sapiens] 115 5e-26 gi|23943886 Rhox homeobox family, member 1 [Homo sapiens] 109 4e-24 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 104 2e-22 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 104 2e-22 gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 103 2e-22 gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 99 7e-21 gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 99 9e-21 gi|14149760 orthopedia homeobox [Homo sapiens] 99 9e-21 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 98 1e-20 gi|7706501 WW domain binding protein 11 [Homo sapiens] 97 3e-20 gi|24497589 aristaless related homeobox [Homo sapiens] 96 6e-20 gi|4557489 cone-rod homeobox protein [Homo sapiens] 96 6e-20 gi|7706659 paired related homeobox 2 [Homo sapiens] 95 1e-19 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 3e-19 gi|169881277 PROP paired-like homeobox 1 [Homo sapiens] 93 5e-19 gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 92 6e-19 gi|11056038 visual system homeobox 1 isoform a [Homo sapiens] 92 1e-18 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 91 2e-18 gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 91 2e-18 gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 91 2e-18 gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 91 2e-18 gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 91 2e-18 gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 91 2e-18 gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 91 2e-18 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 90 4e-18 gi|122937321 UNC homeobox [Homo sapiens] 90 4e-18 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 870 bits (2248), Expect = 0.0 Identities = 406/406 (100%), Positives = 406/406 (100%) Query: 1 MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN 60 MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN Sbjct: 1 MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN 60 Query: 61 VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG 120 VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG Sbjct: 61 VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG 120 Query: 121 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE 180 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE Sbjct: 121 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE 180 Query: 181 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ 240 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ Sbjct: 181 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ 240 Query: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM 300 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM Sbjct: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM 300 Query: 301 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG 360 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG Sbjct: 301 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG 360 Query: 361 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF 406 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF Sbjct: 361 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF 406 >gi|126116581 retina and anterior neural fold homeobox [Homo sapiens] Length = 346 Score = 120 bits (301), Expect = 2e-27 Identities = 91/306 (29%), Positives = 123/306 (40%), Gaps = 60/306 (19%) Query: 56 EAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEP-PLLELKQEQEEPP 114 E + +G + P ++ G EP PP P + E P P + + P Sbjct: 62 ERDRRLGARPACPKAPEE-----GSEPSP----PPAPAPAPEYEAPRPYCPKEPGEARPS 112 Query: 115 QTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAA 174 GP E + +E QP ++ RR RT FT +QL ELE F++S YPDV +RE LA Sbjct: 113 PGLPVGPATGEA-KLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAG 171 Query: 175 RLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALC 234 ++NL E RVQVWFQNRRAKW+R +++ + Sbjct: 172 KVNLPEVRVQVWFQNRRAKWRRQEKLEVSS------------------------------ 201 Query: 235 VHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPV 294 +L P+L PP + P+ P P +P S + P PG + Sbjct: 202 ----MKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATAL 257 Query: 295 PPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPM 354 P PP +P P PP PP P P GP + PL P PP Sbjct: 258 QSLPGFG-----PPAQSLPAS--YTPPPPPPPFLNSP--------PLGPGLQPLAPPPPS 302 Query: 355 APLPPG 360 P PG Sbjct: 303 YPCGPG 308 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 116 bits (291), Expect = 3e-26 Identities = 73/170 (42%), Positives = 103/170 (60%), Gaps = 24/170 (14%) Query: 241 LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP+ +P+PP P A +PP P+P G+ + P PP P A +PP Sbjct: 942 IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPP 999 Query: 297 WPPM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM- 345 PP+ A +PP PP+ A +P PP+ A +PP PP+ A +PP PP+ A +PP PP+ Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059 Query: 346 -APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 A +PP PP+ A +PP PP+ A +PP PP+ A +PP +P G+ P Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109 Score = 115 bits (288), Expect = 7e-26 Identities = 80/197 (40%), Positives = 111/197 (56%), Gaps = 29/197 (14%) Query: 219 LGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMP----PRPPMVP---MPPRPPI--AP 269 L GA P P + L P LP + P PP+P P PP +P +PP PP+ A Sbjct: 948 LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007 Query: 270 MPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM--APVPPWPPM--APVPTGPPM--APVPP 323 +PP P+ PG+ + P PP P A +PP PP+ A +PP PP+ A +P PP+ A +PP Sbjct: 1008 IPPPPPL-PGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065 Query: 324 GPPM--ARVPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM- 372 PP+ A +PP PP+ A +PP PP+ A +PP PP+ +PP PP+ A +PP PP+ Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1125 Query: 373 -APLPPRSHVPHTGLAP 388 A +PP +P G+ P Sbjct: 1126 GAGIPPPPPLPGAGIPP 1142 Score = 112 bits (280), Expect = 6e-25 Identities = 80/202 (39%), Positives = 111/202 (54%), Gaps = 29/202 (14%) Query: 214 PLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMP----PRPPMVP---MPPRPP 266 PL L GA P P + P LP + P PP+P P PP +P +PP PP Sbjct: 965 PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024 Query: 267 I--APMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM--APVPPWPPM--APVPTGPPM-- 318 + A +PP P+P G+ + P PP P A +PP PP+ A +PP PP+ A +P PP+ Sbjct: 1025 LPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1082 Query: 319 APVPPGPPM--ARVPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPP 368 A +PP PP+ A +PP PP+ +PP PP+ A +PP PP+ A +PP PP+ A +PP Sbjct: 1083 AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142 Query: 369 GPPM--APLPPRSHVPHTGLAP 388 PP+ +PP +P G+ P Sbjct: 1143 PPPLPRVGIPPPPPLPGAGIPP 1164 Score = 112 bits (279), Expect = 8e-25 Identities = 71/169 (42%), Positives = 98/169 (57%), Gaps = 22/169 (13%) Query: 241 LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP+ +P PP P A +PP P+P G+ + P PP P + PP Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGVGIPPP 1110 Query: 297 WP-PMAPVPPWPPM--APVPTGPPM--APVPPGPPMARV--PPGPPM--ARVPPGPPM-- 345 P P A +PP PP+ A +P PP+ A +PP PP+ RV PP PP+ A +PP PP+ Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG 1170 Query: 346 APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 A +PP PP+ +PP PP+ +PP PP+ A +PP +P G+ P Sbjct: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP 1219 Score = 111 bits (277), Expect = 1e-24 Identities = 72/170 (42%), Positives = 99/170 (58%), Gaps = 24/170 (14%) Query: 241 LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP+ +P PP P A +PP P+P G+ + P PP P A +PP Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPP 1098 Query: 297 WPPMAPV--PPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPMARV--PPGPPM- 345 PP+ V PP PP+ A +P PP+ A +PP PP+ A +PP PP+ RV PP PP+ Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158 Query: 346 -APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 A +PP PP+ A +PP PP+ +PP PP+ +PP +P G+ P Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208 Score = 110 bits (276), Expect = 2e-24 Identities = 77/179 (43%), Positives = 106/179 (59%), Gaps = 34/179 (18%) Query: 242 PRPPVLP---VPPMP----PRPP------MVPMPPRP-PIAPMPPMAPVPPGSRMAPVPP 287 P PP LP VP +P P+PP M+P PP P P A +PP P+P G+ + P+PP Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP-GAGILPLPP 936 Query: 288 GPRMAPVPPWPPM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--A 337 P A +PP PP+ A +PP PP+ A +P PP+ A +PP PP+ A +PP PP+ A Sbjct: 937 LPG-AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 995 Query: 338 RVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 +PP PP+ A +PP PP+ A +PP PP+ A +PP PP+ A +PP +P G+ P Sbjct: 996 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1054 Score = 110 bits (276), Expect = 2e-24 Identities = 70/168 (41%), Positives = 98/168 (58%), Gaps = 22/168 (13%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP 298 P LP +LP+PP+P +P PP P A +PP P+P P+PP A +PP P Sbjct: 924 PPLPGAGILPLPPLPGAG--IPPPPPLPGAAIPPPPPLPGAG--IPLPPPLPGAGIPPPP 979 Query: 299 PM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM--A 346 P+ A +PP PP+ A +P PP+ A +PP PP+ A +PP PP+ A +PP PP+ A Sbjct: 980 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039 Query: 347 PLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 +PP PP+ A +PP PP+ A +PP PP+ A +PP +P G+ P Sbjct: 1040 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087 Score = 110 bits (274), Expect = 3e-24 Identities = 77/195 (39%), Positives = 110/195 (56%), Gaps = 39/195 (20%) Query: 231 PALCVHLVPQ--LPRPP------VLPVPP-------MPPRPPM-----VPMPPRPPIAPM 270 P + V +P +P+PP +LP PP +PP PP+ +P+PP P A + Sbjct: 884 PGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPG-AGI 942 Query: 271 PPMAPVPPGSRMAPVPPGPRMA-PVPPWPPMAPVPPWPPM--APVPTGPPM--APVPPGP 325 PP P+ PG+ + P PP P P+PP P A +PP PP+ A +P PP+ A +PP P Sbjct: 943 PPPPPL-PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001 Query: 326 PM--ARVPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM--A 373 P+ A +PP PP+ A +PP PP+ A +PP PP+ A +PP PP+ A +PP PP+ A Sbjct: 1002 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1061 Query: 374 PLPPRSHVPHTGLAP 388 +PP +P G+ P Sbjct: 1062 GIPPPPPLPGAGIPP 1076 Score = 110 bits (274), Expect = 3e-24 Identities = 70/170 (41%), Positives = 99/170 (58%), Gaps = 24/170 (14%) Query: 241 LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP+ +P PP P A +PP P+P G+ + P PP P A +PP Sbjct: 1030 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPP 1087 Query: 297 WPPM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM- 345 PP+ A +PP PP+ +P PP+ A +PP PP+ A +PP PP+ A +PP PP+ Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147 Query: 346 -APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 +PP PP+ A +PP PP+ A +PP PP+ +PP +P G+ P Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197 Score = 106 bits (264), Expect = 4e-23 Identities = 73/175 (41%), Positives = 98/175 (56%), Gaps = 30/175 (17%) Query: 241 LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP+ +P PP P A +PP P+P G + P PP P A +PP Sbjct: 1063 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPG-AGIPP 1120 Query: 297 WPPM--APVPPWPPM--APVPTGPPMAPV--PPGPPM--ARVPPGPPM--ARVPPGPPM- 345 PP+ A +PP PP+ A +P PP+ V PP PP+ A +PP PP+ A +PP PP+ Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180 Query: 346 -APLPPGPPM--APLPPGPPM--APLPPGPPM-------APLPPRSHVPHTGLAP 388 +PP PP+ +PP PP+ A +PP PP+ AP PP P TG+ P Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP-PPGTGIPP 1234 Score = 105 bits (262), Expect = 7e-23 Identities = 70/189 (37%), Positives = 99/189 (52%), Gaps = 28/189 (14%) Query: 227 PALDPALCVHLVPQLPRPPVLPVPPMP------PRPPMVPMPPRPPIAP---MPPMAPVP 277 P+ P C +P ++P PP P P P +P PP+ +PP P Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915 Query: 278 PGSRMAPVP--PGPRMAPVPPWPPMAPVPPWPPM--APVPTGPPM----APVPPGPPMAR 329 PG+ + P P PG + P+PP P A +PP PP+ A +P PP+ P+PP P A Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPG-AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG 974 Query: 330 VPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRS 379 +PP PP+ A +PP PP+ A +PP PP+ A +PP PP+ A +PP PP+ A +PP Sbjct: 975 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1034 Query: 380 HVPHTGLAP 388 +P G+ P Sbjct: 1035 PLPGAGIPP 1043 Score = 103 bits (258), Expect = 2e-22 Identities = 66/162 (40%), Positives = 89/162 (54%), Gaps = 22/162 (13%) Query: 241 LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP+ +P PP P A +PP P+P G+ + P PP PR+ PP Sbjct: 1096 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPP 1154 Query: 297 WP-PMAPVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM-- 345 P P A +PP PP+ A +P PP+ +PP PP+ +PP PP+ A +PP PP+ Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1214 Query: 346 -----APLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVP 382 AP PP PP P PP+ P+ GPP+ P S +P Sbjct: 1215 MGIPPAPAPPLPPPGTGIPPPPLLPV-SGPPLLPQVGSSTLP 1255 Score = 95.1 bits (235), Expect = 1e-19 Identities = 65/162 (40%), Positives = 85/162 (52%), Gaps = 20/162 (12%) Query: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMA-PVPPGSRMAPVPP--GPRMAPVPPW 297 +P PP LP P + M P PP P+P M P P + + PP G M P PP Sbjct: 855 IPSPPPLPCTESSSSMPGLGMVPPPP-PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913 Query: 298 P-PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPM--ARVPPGPPM----APLPP 350 P P A +PP PP+ G + P+PP P A +PP PP+ A +PP PP+ PLPP Sbjct: 914 PLPGAGIPPPPPL----PGAGILPLPP-LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968 Query: 351 GPPMAPLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388 P A +PP PP+ A +PP PP+ A +PP +P G+ P Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1010 Score = 62.8 bits (151), Expect = 5e-10 Identities = 47/133 (35%), Positives = 60/133 (45%), Gaps = 25/133 (18%) Query: 241 LPRPPVLP---VPPMPPRPPM-VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 +P PP LP +PP PP P + +P PP P A +PP P+P +PP AP PP Sbjct: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG----MGIPP----APAPP 1224 Query: 297 WPPMAPVPPWPPMAPVPTGPPMAP------VPPGPPMARVPPGPPMA------RVPPGPP 344 PP P PP+ PV +GPP+ P +P +PP P G Sbjct: 1225 LPPPGTGIPPPPLLPV-SGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSR 1283 Query: 345 MAPLPPGPPMAPL 357 P+ P PM PL Sbjct: 1284 KQPIEPCRPMKPL 1296 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/182 (26%), Positives = 61/182 (33%), Gaps = 35/182 (19%) Query: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVP-----------PGSRMAPVPPGP 289 L PPV +P PP PP P+ + P P ++ PP P Sbjct: 755 LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP 814 Query: 290 RMAPVPPWPPMAPVPPWPPMAPVPTGPPMA-----------PVPPGPPMARVPPGPP-MA 337 + PP T + P PP P P + Sbjct: 815 SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLG 874 Query: 338 RVPPGPPMAPLP----PGPPMAPLPPGPP-----MAPLPPGP-PMAPLPPRSHVPHTGLA 387 VPP PP PLP P P +P PP M P PP P P A +PP +P G+ Sbjct: 875 MVPPPPP--PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL 932 Query: 388 PV 389 P+ Sbjct: 933 PL 934 Score = 37.0 bits (84), Expect = 0.032 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 30/121 (24%) Query: 219 LGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMP-------PRPPMVP----MPPRPPI 267 L G P P + + P LP + P PP+P P PP+ P +PP PP+ Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP-PPL 1237 Query: 268 APM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPP--------------MAPVPPWPPMAP 311 P+ PP+ P GS P P P PP P P+ P PM P Sbjct: 1238 LPVSGPPLLP-QVGSSTLPTPQVCGFLP-PPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295 Query: 312 V 312 + Sbjct: 1296 L 1296 Score = 35.0 bits (79), Expect = 0.12 Identities = 65/280 (23%), Positives = 95/280 (33%), Gaps = 48/280 (17%) Query: 113 PPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERL 172 P + V G AE +TA G Q +R ++ +F ++ D+++ + Sbjct: 149 PAEARVGGRPIAEDVETAAGAQDGQRTSSGSDT-------DIYSFHSATEQEDLLSDIQQ 201 Query: 173 AARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTA---TADLAHP-----LDMFL----G 220 A RL + + Q Q + + ++ Q++ A TA P LD FL G Sbjct: 202 AIRL---QQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSG 258 Query: 221 GAYYAAPALDPALCVHLVPQLPRPPVLPV--PPMPPRPPMVPMPPRPPIAPMPPMAPVPP 278 GA A + D + + LP P PP P +P+ P + P A P Sbjct: 259 GAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSP 318 Query: 279 GSRMAPVP---PGPRMAPVP-----------------PWPPMAPVPPWPPMAPVPTGPPM 318 S P P PG A P P +P W P V P Sbjct: 319 SSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAP--EVGEDAPQ 376 Query: 319 APVPPGPPMARVPPGPPMARVP--PGPPMAPLPPGPPMAP 356 A+ P P A +P P P P P + P Sbjct: 377 RLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITP 416 Score = 30.8 bits (68), Expect = 2.3 Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 3/41 (7%) Query: 95 EQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135 +QQQ++ L+L+Q+Q+ Q ++G + P TA PQP Sbjct: 206 QQQQQQQLQLQLQQQQQ---QQQLQGAEEPAAPPTAVSPQP 243 >gi|14249119 Rhox homeobox family, member 2 [Homo sapiens] Length = 288 Score = 116 bits (291), Expect = 3e-26 Identities = 87/258 (33%), Positives = 122/258 (47%), Gaps = 32/258 (12%) Query: 21 EDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQD-----RE 75 +D +E+ D V SL E+EE+ + +PE GT A + + G+ +++D ++ Sbjct: 20 DDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKD 79 Query: 76 GGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135 GGG P E E +E + E+ P PQ A G G +P Sbjct: 80 GGGAGVPGHLWEGDL----EGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVG-----GLEP 130 Query: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195 ++ AFT QLQELE F Q+P R RLA +N+TE VQ+WF+NRRAKW+ Sbjct: 131 GNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWR 190 Query: 196 RNQRVLMLRN-----------TATADLAHPLDMFLGGA---YYAAPALDPALCVHLVPQL 241 R+QR LM RN TA A +F+ G Y+ + +LC + P Sbjct: 191 RHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPM-PPF 249 Query: 242 PRPPVLPVPPM--PPRPP 257 P PP LP+P M PP PP Sbjct: 250 P-PPSLPLPLMLLPPMPP 266 Score = 28.9 bits (63), Expect = 8.7 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%) Query: 302 PVPPWPPMAPVPTGP-PMAPVPPGPPMARVPPGP-PMARVP 340 P+PP+PP P+ P P+ +PP PP + GP P VP Sbjct: 245 PMPPFPP----PSLPLPLMLLPPMPPAGQAEFGPFPFVIVP 281 >gi|153791494 Rhox homeobox family, member 2B [Homo sapiens] Length = 288 Score = 115 bits (289), Expect = 5e-26 Identities = 87/258 (33%), Positives = 122/258 (47%), Gaps = 32/258 (12%) Query: 21 EDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQD-----RE 75 +D +E+ D V SL E+EE+ + +PE GT A + + G+ +++D ++ Sbjct: 20 DDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKD 79 Query: 76 GGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135 GGG P E E +E + E+ P PQ A G G +P Sbjct: 80 GGGAGVPGHLWEG----NLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVG-----GLEP 130 Query: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195 ++ AFT QLQELE F Q+P R RLA +N+TE VQ+WF+NRRAKW+ Sbjct: 131 GNAQQPNVHAFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWR 190 Query: 196 RNQRVLMLRN-----------TATADLAHPLDMFLGGA---YYAAPALDPALCVHLVPQL 241 R+QR LM RN TA A +F+ G Y+ + +LC + P Sbjct: 191 RHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPM-PPF 249 Query: 242 PRPPVLPVPPM--PPRPP 257 P PP LP+P M PP PP Sbjct: 250 P-PPSLPLPLMLLPPMPP 266 Score = 28.9 bits (63), Expect = 8.7 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%) Query: 302 PVPPWPPMAPVPTGP-PMAPVPPGPPMARVPPGP-PMARVP 340 P+PP+PP P+ P P+ +PP PP + GP P VP Sbjct: 245 PMPPFPP----PSLPLPLMLLPPMPPAGQAEFGPFPFVIVP 281 >gi|23943886 Rhox homeobox family, member 1 [Homo sapiens] Length = 184 Score = 109 bits (273), Expect = 4e-24 Identities = 66/160 (41%), Positives = 84/160 (52%), Gaps = 35/160 (21%) Query: 51 PEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ 110 PE G EN + +G + + GGG EP QQ + PP Sbjct: 50 PEGGVNHENGMNRDGGMIPEG----GGGNQEPRQQPQPPP-------------------- 85 Query: 111 EEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARE 170 EEP Q +EGPQP E QP R RRT FT Q++ELE+ F +QYPDV R Sbjct: 86 EEPAQAAMEGPQP-------ENMQP----RTRRTKFTLLQVEELESVFRHTQYPDVPTRR 134 Query: 171 RLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATAD 210 LA L +TED+V+VWF+N+RA+ +R+QR LML N AD Sbjct: 135 ELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRAD 174 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 104 bits (259), Expect = 2e-22 Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 31/197 (15%) Query: 232 ALCVHLVPQLP-RPPVLPVPPMP-------PRPPM-----VPMPPRPPIAPMPPMA---- 274 A + + P +P R PV P PP+P P PP P PP PP P PP+ Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 617 Query: 275 -----PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMAR 329 +P G+ ++P PP A +PP PP+ P + +P G + P PP P AR Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 677 Query: 330 VPPGPP----MARVPPGPPMAP----LPPGPPMAPLPPG-PPMAPLPPGPPMAPLPPRSH 380 +PP PP A +PP PP P +PP PP P PG PP P P GP + P PP Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737 Query: 381 VPHTGLAPVHITWAPVI 397 +P + APV+ Sbjct: 738 MPPPPPFGFGVPAAPVL 754 Score = 92.4 bits (228), Expect = 6e-19 Identities = 58/152 (38%), Positives = 74/152 (48%), Gaps = 16/152 (10%) Query: 227 PALDPALCVHLVPQLPRPPVL-PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285 P L +C+ P LP + P PP+ + P PP P +P + +P G+ + P Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 669 Query: 286 PPGPRMAPVPPWPPMAP----VPPWPPMAPVPTG--PPMAPVPPGPPMARVPPGPPMARV 339 PP P A +PP PP P +PP PP P G PP P+P GP +PP PP Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG---IPPPPPF--- 723 Query: 340 PPGPPMAPLPPGPPMAPLPP---GPPMAPLPP 368 P GP + P PPG M P PP G P AP+ P Sbjct: 724 PGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 104 bits (259), Expect = 2e-22 Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 31/197 (15%) Query: 232 ALCVHLVPQLP-RPPVLPVPPMP-------PRPPM-----VPMPPRPPIAPMPPMA---- 274 A + + P +P R PV P PP+P P PP P PP PP P PP+ Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 626 Query: 275 -----PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMAR 329 +P G+ ++P PP A +PP PP+ P + +P G + P PP P AR Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686 Query: 330 VPPGPP----MARVPPGPPMAP----LPPGPPMAPLPPG-PPMAPLPPGPPMAPLPPRSH 380 +PP PP A +PP PP P +PP PP P PG PP P P GP + P PP Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746 Query: 381 VPHTGLAPVHITWAPVI 397 +P + APV+ Sbjct: 747 MPPPPPFGFGVPAAPVL 763 Score = 92.4 bits (228), Expect = 6e-19 Identities = 58/152 (38%), Positives = 74/152 (48%), Gaps = 16/152 (10%) Query: 227 PALDPALCVHLVPQLPRPPVL-PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285 P L +C+ P LP + P PP+ + P PP P +P + +P G+ + P Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 678 Query: 286 PPGPRMAPVPPWPPMAP----VPPWPPMAPVPTG--PPMAPVPPGPPMARVPPGPPMARV 339 PP P A +PP PP P +PP PP P G PP P+P GP +PP PP Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG---IPPPPPF--- 732 Query: 340 PPGPPMAPLPPGPPMAPLPP---GPPMAPLPP 368 P GP + P PPG M P PP G P AP+ P Sbjct: 733 PGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764 >gi|14249388 retina and anterior neural fold homeobox 2 [Homo sapiens] Length = 184 Score = 103 bits (258), Expect = 2e-22 Identities = 66/153 (43%), Positives = 80/153 (52%), Gaps = 34/153 (22%) Query: 123 PAEGPQTAEG------PQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARL 176 P EGP T G P ++ RR RT FT +QL +LE F+ S YPDV +RE LAA++ Sbjct: 5 PGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKV 64 Query: 177 NLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVH 236 +L E RVQVWFQNRRAKW+R +R + G AAP L A Sbjct: 65 HLPEVRVQVWFQNRRAKWRRQER-----------------LESGSGAVAAPRLPEA---- 103 Query: 237 LVPQLP--RPPVLPVPPMP---PRPPMVPMPPR 264 P LP RPP + +P P P PP VP PR Sbjct: 104 --PALPFARPPAMSLPLEPWLGPGPPAVPGLPR 134 Score = 30.0 bits (66), Expect = 3.9 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 9/59 (15%) Query: 329 RVPPGP--PMARVPPGPPMAPLPPGPPMAPLPPGPPMAP--LPPGPPM-APLPPRSHVP 382 R+P P P AR PP LP P + P PP P P L PGP + A P + P Sbjct: 99 RLPEAPALPFAR----PPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAP 153 >gi|55743092 aristaless-like homeobox 4 [Homo sapiens] Length = 411 Score = 99.0 bits (245), Expect = 7e-21 Identities = 75/223 (33%), Positives = 103/223 (46%), Gaps = 27/223 (12%) Query: 74 REGGGGHEPEQQ----QEEPPLTKPEQQQEEPPL------LELKQEQEEPPQTTVEGPQP 123 +EG GH Q +E L +PE + + L +K+ + PQ P Sbjct: 140 QEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLP 199 Query: 124 AEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRV 183 + + A+ +KRR RT FT +QL+ELE F ++ YPDV ARE+LA R +LTE RV Sbjct: 200 SP-LEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARV 258 Query: 184 QVWFQNRRAKWKRNQRVLMLRNTAT-ADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP 242 QVWFQNRRAKW++ +R ++ T A+ L + YA Q+ Sbjct: 259 QVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYA--------------QIQ 304 Query: 243 RPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285 P L P +P P A M P A PPGS + V Sbjct: 305 NPSWLGNNGAASPVPACVVPCDPVPACMSPHAH-PPGSGASSV 346 >gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] Length = 325 Score = 98.6 bits (244), Expect = 9e-21 Identities = 59/142 (41%), Positives = 74/142 (52%), Gaps = 14/142 (9%) Query: 120 GPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLT 179 GPQ P A Q ++++R RT FT QL ELE F ++ YPD+ RE LA R+ LT Sbjct: 85 GPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144 Query: 180 EDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHP-LDMFLGGAYYAAPALDPALC---- 234 E RVQVWFQNRRAKWK+ ++ + L P L F A AA A+ +LC Sbjct: 145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHA 204 Query: 235 ---------VHLVPQLPRPPVL 247 + V QLP PP L Sbjct: 205 NDTRWAAAAMPGVSQLPLPPAL 226 >gi|14149760 orthopedia homeobox [Homo sapiens] Length = 325 Score = 98.6 bits (244), Expect = 9e-21 Identities = 59/142 (41%), Positives = 74/142 (52%), Gaps = 14/142 (9%) Query: 120 GPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLT 179 GPQ P A Q ++++R RT FT QL ELE F ++ YPD+ RE LA R+ LT Sbjct: 85 GPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144 Query: 180 EDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHP-LDMFLGGAYYAAPALDPALC---- 234 E RVQVWFQNRRAKWK+ ++ + L P L F A AA A+ +LC Sbjct: 145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHA 204 Query: 235 ---------VHLVPQLPRPPVL 247 + V QLP PP L Sbjct: 205 NDTRWAAAAMPGVSQLPLPPAL 226 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 98.2 bits (243), Expect = 1e-20 Identities = 62/143 (43%), Positives = 69/143 (48%), Gaps = 17/143 (11%) Query: 244 PPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPV 303 PP P PPRPP+ P P P P PP +PP P+ P PP P + P Sbjct: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPP-----PLAGPPNRGDRPPPPVLFPG 281 Query: 304 PPW--PPMAPVPTGPPMAPVPP-GPPMARVPP--GPPMARVPPGPPMAPLPPGPPMAPLP 358 P+ PP+ P+P GPP PVP GPP PP GPP PP P P PPGP PL Sbjct: 282 QPFGQPPLGPLPPGPP-PPVPGYGPPPGPPPPQQGPP----PPPGPFPPRPPGPLGPPLT 336 Query: 359 PGPPMAPLPPGPPMAPLPPRSHV 381 PP P PGPP PP HV Sbjct: 337 LAPP--PHLPGPPPGAPPPAPHV 357 Score = 81.3 bits (199), Expect = 1e-15 Identities = 60/162 (37%), Positives = 70/162 (43%), Gaps = 35/162 (21%) Query: 242 PRPPVLPV-PPMPPRPP----MVPMP----------PRPPIA------PMPPMAPVPPGS 280 PRPP+ P PP PP PP ++P P P PP+ PP+ P+PPG Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG- 295 Query: 281 RMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVP----PGPPM 336 P PP P P PP PP P PP P PP P P GPP+ P PGPP Sbjct: 296 ---PPPPVPGYGP-PPGPPPPQQGPPPPPGPF---PPRPPGPLGPPLTLAPPPHLPGPPP 348 Query: 337 ARVPPGPPMAP-LPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377 PP P + P P P + +P P PP P PP Sbjct: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGP-PPTDPYGRPPP 389 Score = 78.6 bits (192), Expect = 1e-14 Identities = 64/156 (41%), Positives = 69/156 (44%), Gaps = 32/156 (20%) Query: 238 VPQLPRPPVLPVPPMPPRP-PMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 VP R P P PP P P PPRPP+ P P PPG PPGP Sbjct: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP-----PGPPG------PPGP------- 252 Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVP---PGPPMARVPPGPPMARVPPGPPMAPLPP-GP 352 PP V P PP+A P P P PG P + P GP +PPGPP P+P GP Sbjct: 253 -PPPGQVLP-PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP----LPPGPP-PPVPGYGP 305 Query: 353 PMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAP 388 P P PP P P PP P P PP P LAP Sbjct: 306 P--PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339 Score = 61.6 bits (148), Expect = 1e-09 Identities = 43/110 (39%), Positives = 47/110 (42%), Gaps = 9/110 (8%) Query: 238 VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW 297 VP PP P P P PP P PPRPP PP+ PP P PGP PP Sbjct: 300 VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP-----PHLPGPPPGAPPPA 354 Query: 298 PPMAPV--PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPM 345 P + P PP P + +PT P PP P R PP PPG M Sbjct: 355 PHVNPAFFPP-PTNSGMPTSDSRGP-PPTDPYGRPPPYDRGDYGPPGREM 402 Score = 39.7 bits (91), Expect = 0.005 Identities = 32/85 (37%), Positives = 34/85 (40%), Gaps = 9/85 (10%) Query: 313 PTGPPMAPVPPGPP-MARVPPGPPMARVPPGPPMA-----PLPPG--PPMAPL-PPGPPM 363 P G A P G R P P PGP P P G PP PL PPGPP Sbjct: 189 PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG 248 Query: 364 APLPPGPPMAPLPPRSHVPHTGLAP 388 P PP P PP + P+ G P Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRP 273 Score = 28.9 bits (63), Expect = 8.7 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 4/67 (5%) Query: 76 GGGGHEPEQQQEEPPLTKPEQQQEE--PPLLELKQEQEEPPQTTVE--GPQPAEGPQTAE 131 G G P Q PPL P + + PP+L Q +PP + P P G Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPP 307 Query: 132 GPQPPER 138 GP PP++ Sbjct: 308 GPPPPQQ 314 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 96.7 bits (239), Expect = 3e-20 Identities = 61/142 (42%), Positives = 68/142 (47%), Gaps = 10/142 (7%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP 298 PQ P + PPMP PP+ P PP PP+ P P +PPG P P P P P Sbjct: 394 PQSVPPSQIQAPPMPGPPPLGP-PPAPPLRPPGPPTGLPPG----PPPGAPPFLRPPGMP 448 Query: 299 PM-APVPPWPPMAPVPTGPPMAP--VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMA 355 + P+P P P P PP P PPG P P GPP PP PP P PP P M Sbjct: 449 GLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIP-PPRPGMM 507 Query: 356 PLPPGPPMAPLPPGP-PMAPLP 376 P PP+ P PPG P APLP Sbjct: 508 RPPLVPPLGPAPPGLFPPAPLP 529 Score = 90.9 bits (224), Expect = 2e-18 Identities = 58/126 (46%), Positives = 61/126 (48%), Gaps = 14/126 (11%) Query: 272 PMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPV---PPGPPMA 328 P VPP AP PGP PP PP+ P P PP P PP AP PPG P Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP--PGPPTGLPPGPPPGAPPFLRPPGMPGL 450 Query: 329 R------VPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVP 382 R +PPGPP R PPGPP P PPG P P P GPP PP PP P PPR + Sbjct: 451 RGPLPRLLPPGPPPGR-PPGPPPGP-PPGLPPGPPPRGPPPRLPPPAPPGIP-PPRPGMM 507 Query: 383 HTGLAP 388 L P Sbjct: 508 RPPLVP 513 Score = 89.0 bits (219), Expect = 7e-18 Identities = 63/139 (45%), Positives = 68/139 (48%), Gaps = 18/139 (12%) Query: 239 PQLPRPPVLPVPPMPP-RPPMVP--MPPRPPIAPMPPMAPVP-PGSR------MAPVPPG 288 P +P PP L PP PP RPP P +PP PP P + P PG R + P PP Sbjct: 405 PPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP 464 Query: 289 PRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPL 348 R PP PP P PP P P PP P PPG P PP P M R P PP+ P Sbjct: 465 GRPPGPPPGPPPGLPPGPPPRGPPPRLPP--PAPPGIP----PPRPGMMRPPLVPPLGPA 518 Query: 349 PPGP-PMAPLP-PGPPMAP 365 PPG P APLP PG AP Sbjct: 519 PPGLFPPAPLPNPGVLSAP 537 Score = 55.5 bits (132), Expect = 9e-08 Identities = 37/90 (41%), Positives = 44/90 (48%), Gaps = 12/90 (13%) Query: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV------PPGPRMAPVP 295 P P +LP P P RPP P P P + P PP PP R+ P PP P M P Sbjct: 453 PLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPP--RLPPPAPPGIPPPRPGMMRPP 510 Query: 296 PWPPMAPVPP--WPPMAPVPTGPPMAPVPP 323 PP+ P PP +PP AP+P P + PP Sbjct: 511 LVPPLGPAPPGLFPP-APLP-NPGVLSAPP 538 Score = 35.0 bits (79), Expect = 0.12 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 7/72 (9%) Query: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAP-MPPMAPVPPGSRMAPV 285 P P L P+ P PP LP P P PP P RPP+ P + P PPG P Sbjct: 472 PGPPPGLPPGPPPRGP-PPRLPPPAPPGIPPPRPGMMRPPLVPPL---GPAPPG-LFPPA 526 Query: 286 P-PGPRMAPVPP 296 P P P + PP Sbjct: 527 PLPNPGVLSAPP 538 Score = 33.9 bits (76), Expect = 0.27 Identities = 25/83 (30%), Positives = 30/83 (36%), Gaps = 14/83 (16%) Query: 269 PMPPMAPVPPGSRMAPVP-PGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPM 327 P+P M P + +P PG + PP GPP V P + Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQ-------------PPSILKKTSAYGPPTRAVSILPLL 186 Query: 328 ARVPPGPPMARVPPGPPMAPLPP 350 P P R PPGPP P PP Sbjct: 187 GHGVPRLPPGRKPPGPPPGPPPP 209 Score = 33.9 bits (76), Expect = 0.27 Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 7/93 (7%) Query: 51 PEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ 110 PE G E E + SDD + E + +++ + QQ+ PP + Sbjct: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402 Query: 111 EEPPQTTVE--GPQPA-----EGPQTAEGPQPP 136 + PP GP PA GP T P PP Sbjct: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPP 435 Score = 31.6 bits (70), Expect = 1.3 Identities = 20/71 (28%), Positives = 26/71 (36%) Query: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLP 367 P+ +P P + P PP GPP + P + P P P Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199 Query: 368 PGPPMAPLPPR 378 PGPP P PP+ Sbjct: 200 PGPPPGPPPPQ 210 Score = 31.2 bits (69), Expect = 1.8 Identities = 21/70 (30%), Positives = 25/70 (35%) Query: 299 PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLP 358 P+ +P P + P PP GPP V P + P P P Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199 Query: 359 PGPPMAPLPP 368 PGPP P PP Sbjct: 200 PGPPPGPPPP 209 Score = 29.6 bits (65), Expect = 5.1 Identities = 22/77 (28%), Positives = 27/77 (35%), Gaps = 6/77 (7%) Query: 247 LPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW 306 +P+P MP P + I +P PP GP V P + P Sbjct: 139 IPLPDMPHAPSNIL------IQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPR 192 Query: 307 PPMAPVPTGPPMAPVPP 323 P P GPP P PP Sbjct: 193 LPPGRKPPGPPPGPPPP 209 Score = 29.3 bits (64), Expect = 6.7 Identities = 40/163 (24%), Positives = 64/163 (39%), Gaps = 40/163 (24%) Query: 123 PAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDR 182 P + PQ E +RK+ R T +L E EN PD+ R + Sbjct: 67 PVQQPQLNEKVLKDKRKKLRETFERILRLYEKEN-------PDIYKELR----------K 109 Query: 183 VQVWFQNRRAKWK------RNQRVLMLRNTATADLAHP------LDMFLGGAYYAAPAL- 229 ++V ++ +RA+ +N + + + + D+ H D+ L GA P++ Sbjct: 110 LEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQ--PPSIL 167 Query: 230 -------DPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPR 264 P V ++P L P LP PP PP P PP+ Sbjct: 168 KKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQ 210 >gi|24497589 aristaless related homeobox [Homo sapiens] Length = 562 Score = 95.9 bits (237), Expect = 6e-20 Identities = 89/287 (31%), Positives = 112/287 (39%), Gaps = 78/287 (27%) Query: 55 TEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ---- 110 T E +G G P GG G E + EE L E + EE LLE +E+ Sbjct: 199 THPEERLGVAGG-PGSAPAAGGGTGTEDD---EEELLEDEEDEDEEEELLEDDEEELLED 254 Query: 111 ------EEPPQTTV----------------EGPQ--PAEG----PQTAEGPQPPE----- 137 +EP + V EG + P E P+ AEG + Sbjct: 255 DARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLS 314 Query: 138 ------------RKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQV 185 ++RR RT FT +QL+ELE F ++ YPDV RE LA RL+LTE RVQV Sbjct: 315 AGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQV 374 Query: 186 WFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPP 245 WFQNRRAKW++ ++ HP + P P H P P Sbjct: 375 WFQNRRAKWRKREK--------AGAQTHPPGL---------PFPGPLSATH-----PLSP 412 Query: 246 VLPVPPMPPRPPMVP---MPPRPPIAPMPPMAPVPPGSRMAPVPPGP 289 L P PP P + A P P PPGS P P Sbjct: 413 YLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAP 459 Score = 29.6 bits (65), Expect = 5.1 Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 13/65 (20%) Query: 322 PPGPPMARVPPGPPMARVPPGPPM--APLPPGPPM-------APLPPGPPMAPLPPGPPM 372 PPG P PGP A P P + +P PP P A LPP P Sbjct: 395 PPGLPF----PGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGS 450 Query: 373 APLPP 377 A LPP Sbjct: 451 ASLPP 455 >gi|4557489 cone-rod homeobox protein [Homo sapiens] Length = 299 Score = 95.9 bits (237), Expect = 6e-20 Identities = 84/262 (32%), Positives = 112/262 (42%), Gaps = 40/262 (15%) Query: 118 VEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLN 177 + GP Q P P ++RR RT FT+ QL+ELE F ++QYPDV ARE +A ++N Sbjct: 18 LSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKIN 77 Query: 178 LTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHL 237 L E RVQVWF+NRRAK ++ ++ + GG A PA A Sbjct: 78 LPESRVQVWFKNRRAKCRQQRQQQKQQQQPP-----------GGQAKARPAKRKA----- 121 Query: 238 VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW 297 PRP + P P + PP+ P P GS P +A V W Sbjct: 122 -GTSPRPST----DVCPDPLGISDSYSPPL-------PGPSGS------PTTAVATVSIW 163 Query: 298 PPM--APVPPWPPMAPVPTGPPMAPVPPGPPMARVPP--GPPMARVPPGPPMAPLPPG-P 352 P +P+P V +GP + P A P A P + L P Sbjct: 164 SPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLS 223 Query: 353 PMAPLPPGPPMAPLPPGPPMAP 374 PM P GP ++PL GP + P Sbjct: 224 PMVPQLGGPALSPL-SGPSVGP 244 >gi|7706659 paired related homeobox 2 [Homo sapiens] Length = 253 Score = 95.1 bits (235), Expect = 1e-19 Identities = 63/174 (36%), Positives = 82/174 (47%), Gaps = 30/174 (17%) Query: 121 PQPAEGPQTAEGPQPPERK--RRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNL 178 PQ E P G +K RR RT F QLQ LE F+ + YPD RE LA R+NL Sbjct: 84 PQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNL 143 Query: 179 TEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLV 238 +E RVQVWFQNRRAK++RN+R ++ +A+ L +Y A++ Sbjct: 144 SEARVQVWFQNRRAKFRRNERAMLASRSAS----------LLKSYSQEAAIEQ------- 186 Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292 P PRP L P + P + +PP +P G P PG MA Sbjct: 187 PVAPRPTAL-------SPDYLSWTASSPYSTVPPYSPGSSG----PATPGVNMA 229 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 93.6 bits (231), Expect = 3e-19 Identities = 60/174 (34%), Positives = 80/174 (45%), Gaps = 16/174 (9%) Query: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPR-PPMVPMPP--RPPIAPM-PPMAPVPPGSRM 282 P PAL + LP PP+ P+ PP+ PP + +PP PP P PP++P+ S Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651 Query: 283 APVPPGPRMAPVPPWPPMAPV-------PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPP 335 AP + P PP +P P PP++P T P AP P +VPP PP Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711 Query: 336 MARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPV 389 + PPM+P PP AP P P +PP PP +P S P + P+ Sbjct: 712 AS-----PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760 Score = 87.4 bits (215), Expect = 2e-17 Identities = 59/166 (35%), Positives = 70/166 (42%), Gaps = 22/166 (13%) Query: 226 APALDPALCVHLVPQLPRPPVLPVPPM--PPRPPMVPMPPRPPIAPMPPMAPVPPGSRMA 283 +P P + P PP L PP+ PP PP PP P A PP AP P + Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAPPPLAAPPL 735 Query: 284 PVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGP 343 VPP P P PPM+P T PP P P +VPP PP A +P P Sbjct: 736 QVPPSP--------------PASPPMSPSATPPPRVPPLLAAPPLQVPPSPP-ASLPMSP 780 Query: 344 PMAPLPPGPPMAPLPPGPPMAPLPPG--PPMAPLPPRSHVPHTGLA 387 P P PP PP + P PP P AP P + +P + LA Sbjct: 781 LAKPPPQAPPALATPPLQAL-PSPPASFPGQAPFSPSASLPMSPLA 825 Score = 85.1 bits (209), Expect = 1e-16 Identities = 68/190 (35%), Positives = 86/190 (45%), Gaps = 35/190 (18%) Query: 225 AAPALDPALCVHLVPQLPRP---PVLPVPPMPPR----------PPMVP---------MP 262 A+P + P+ PQ P P P L VPP PP PP VP +P Sbjct: 712 ASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769 Query: 263 PRPPIA-PMPPMAPVPPGSRMAPVPPGPRMAPVPP--WPPMAPVPPWP--PMAPVPTGPP 317 P PP + PM P+A PP + A P + P PP +P AP P PM+P+ T PP Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Query: 318 MAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377 AP P+ +VPP PP + P P PGP + P +A L PGPP PP Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSGPRLTLA-LAPGPP----PP 883 Query: 378 RSHVPHTGLA 387 S P + L+ Sbjct: 884 PSRSPSSTLS 893 Score = 82.0 bits (201), Expect = 9e-16 Identities = 67/186 (36%), Positives = 81/186 (43%), Gaps = 37/186 (19%) Query: 239 PQLPRPPVLPVPPMPPR-PPMVPMPPRPPIAPMPPMAP---VPPGSRMAP-----VPPGP 289 P L PP L VPP PP PPM P PP AP P AP VPP +P P P Sbjct: 697 PSLAAPP-LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755 Query: 290 RMAP--------VPPWPPM-APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMA--- 337 R+ P VPP PP PM+P+ PP AP P + P PP + Sbjct: 756 RVPPLLAAPPLQVPPSPPASL------PMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809 Query: 338 RVPPGP----PMAPLPPGPPMAPLPPGPPMAPLPPGPP-----MAPLPPRSHVPHTGLAP 388 + P P PM+PL PP AP P+ +PP PP AP P + P T ++ Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869 Query: 389 VHITWA 394 +T A Sbjct: 870 PRLTLA 875 Score = 77.4 bits (189), Expect = 2e-14 Identities = 59/194 (30%), Positives = 73/194 (37%), Gaps = 25/194 (12%) Query: 225 AAPALDPALCVHLVPQLPRPPVLPVPPM-----PPRPPMVPMPPRPPIAPMPPMAPVPPG 279 A P+L P L P L PP+ P P + PP P AP P AP P Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP--APCPLQAPPSPL 576 Query: 280 SRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV 339 + P P P P PP PP + P P P P PP +PP Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636 Query: 340 PPGPPMAPLPPGPPMAP-------------LPPGPPM-APL--PPGPPMAP--LPPRSHV 381 P PP++PL P AP PP PP+ AP P PP++P PP Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696 Query: 382 PHTGLAPVHITWAP 395 P P+ + +P Sbjct: 697 PSLAAPPLQVPPSP 710 Score = 75.9 bits (185), Expect = 6e-14 Identities = 60/191 (31%), Positives = 75/191 (39%), Gaps = 25/191 (13%) Query: 204 RNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPP-----RPPM 258 R +A L P L + A P PA PR P P P P RPP Sbjct: 227 RPSAGGGLQRPASRSLSSS--ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284 Query: 259 VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPM 318 V PPR AP + P+ P P G + PVPP P P+P Sbjct: 285 VT-PPRKDAAPA--LGPLSSSPLATPSPSGTKARPVPP--------PDNAATPLP----- 328 Query: 319 APVPPGPPMAR-VPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377 A +PP PP+A +P PP PP P PP P + PP P+ P + +PP Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388 Query: 378 RSHVPHTGLAP 388 VPH+ +P Sbjct: 389 -IQVPHSLTSP 398 Score = 72.4 bits (176), Expect = 7e-13 Identities = 56/171 (32%), Positives = 77/171 (45%), Gaps = 24/171 (14%) Query: 239 PQLPRPPVLPVPPMPPR----PPMVPMPPR----PPIAPMPPMAPVPPGSRMAPV----- 285 PQ P ++ +PP+ + PP + PP PP+ +P +AP P + AP+ Sbjct: 500 PQAPLSSLI-MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558 Query: 286 --PPGPRMAPVPPWPPMAPVPPWPPMAP--VPTGPPMAPVP-PGPPMARVPPGP--PMAR 338 PP P AP P P +P+ PP P + T PP AP PP+ +P P P+A Sbjct: 559 ETPPCP--APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT 616 Query: 339 VPP-GPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAP 388 PP PP LPP P PP++PL P AP H+ +P Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667 Score = 68.9 bits (167), Expect = 8e-12 Identities = 60/162 (37%), Positives = 71/162 (43%), Gaps = 19/162 (11%) Query: 225 AAPALDP-ALCVHLVPQLPRPPVLPVPPMPPRP-PMVPMPPRPPIAP----MPPMA--PV 276 A+P + P A VP L P L VPP PP PM P+ PP AP PP+ P Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802 Query: 277 PPGSRMAPVPPGPR----MAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPP 332 PP S P P M+P+ PP AP P+ VP PP +P P R PP Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPP 859 Query: 333 GPPMARVPPGPPMA-PLPPGPPMAPLPPGPPMAPLPPGPPMA 373 P GP + L PGPP P P P + L GP +A Sbjct: 860 TPGPDTSVSGPRLTLALAPGPP--PPPSRSPSSTL-SGPDLA 898 Score = 64.3 bits (155), Expect = 2e-10 Identities = 45/132 (34%), Positives = 53/132 (40%), Gaps = 6/132 (4%) Query: 266 PIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGP 325 P AP P P P G + A PP P + P+ P P P+G PVPP Sbjct: 263 PRAPAHPSQPKPKGLQ-ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321 Query: 326 PMARVPPGPPMARVPPGPPMA-PLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHT 384 A P A +PP PP+A PLP PP PP P PP P + PP P Sbjct: 322 NAATPLP----ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377 Query: 385 GLAPVHITWAPV 396 P T P+ Sbjct: 378 QAPPSLQTIPPI 389 Score = 52.4 bits (124), Expect = 7e-07 Identities = 47/171 (27%), Positives = 67/171 (39%), Gaps = 23/171 (13%) Query: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPP 299 P P P PP + +P PP+ P ++P+ + P+ +A P P Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503 Query: 300 MAPV--PPW-------PPMAPVP----TGPPMAPVPP--GPPM--ARVPPGPPMARVPPG 342 ++ + PP PP P T PP+ +P PP+ A P P PP Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC 563 Query: 343 PPMAPLPPGP-PMAPLPPGPPMA---PLPPGPPMAPLPPRSHVPHTGLAPV 389 P PL P P+ PP P + P P PP PP +P L+P+ Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614 Score = 47.0 bits (110), Expect = 3e-05 Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 34/180 (18%) Query: 225 AAPALDPALCVHLVPQLPRP----PVLP-----------VPPMPPRPPMVPM-PPRPPIA 268 AAPAL P L P PV P +PP PP +P+ PP P Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351 Query: 269 PMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGP--- 325 P P PP + + PP P+ P + +P P P P PP P Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--PIQVPHSLTSPSLQAPPSPLAL 409 Query: 326 --PMARVPPGPPMAR-------VPPGPPMAPL-PPGPPMAPLPPGPPM-AP--LPPGPPM 372 A G P + + P A L P P + P PP+ AP LP PP+ Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469 Score = 41.2 bits (95), Expect = 0.002 Identities = 54/222 (24%), Positives = 74/222 (33%), Gaps = 50/222 (22%) Query: 226 APALDPALCVHLVPQLPRPPVLP---VPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRM 282 +P+ P+L LP PP P PP PPM P I P+ + S Sbjct: 347 SPSAPPSL-----QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401 Query: 283 APVPP-------------GPRMAPVPPWPPMAP-------VPPWPPMAPVPTGPPM-AP- 320 AP P P + + M+P P P + P PP+ AP Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461 Query: 321 -VPPGPPM-----ARVPPGPPMARVPPGPPMAPLPPGPPMAPL-----PP-------GPP 362 +P PP+ V P + P ++ L P APL PP PP Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521 Query: 363 MAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACP 404 PP PP ++P P+ AP+ + P Sbjct: 522 SLQTPPA--SLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561 Score = 32.0 bits (71), Expect = 1.0 Identities = 30/105 (28%), Positives = 36/105 (34%), Gaps = 6/105 (5%) Query: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVP-PGPRMAPVPPWPPM 300 PRPP P PP P P + + P+A G A +P PR P Sbjct: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86 Query: 301 APVPPWPPMAP--VPTGPPMAPVPPGPPMARVPPGPPMARVPPGP 343 + P P A PP PGP + PG PGP Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSS---PGRASGTTRPGP 128 Score = 30.8 bits (68), Expect = 2.3 Identities = 27/104 (25%), Positives = 33/104 (31%), Gaps = 3/104 (2%) Query: 261 MPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320 + PRPP +P PP P R+ P+ P AP A Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84 Query: 321 VPPGPPMARVPPGPPMARVPPGPPMAPLP---PGPPMAPLPPGP 361 P +R P R PP +P P PG PGP Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128 >gi|169881277 PROP paired-like homeobox 1 [Homo sapiens] Length = 226 Score = 92.8 bits (229), Expect = 5e-19 Identities = 72/212 (33%), Positives = 99/212 (46%), Gaps = 40/212 (18%) Query: 93 KPEQQQEEPPLLELKQEQEEPPQTTVEGPQP-------AEGPQTAEGPQP-----PERKR 140 KP++ + LL + P TTV+ P A G ++ PQ P +R Sbjct: 11 KPKKGRVGSNLLPERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRR 70 Query: 141 RRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRV 200 R RT F+ QL++LE+ F +QYPD+ ARE LA L+E R+QVWFQNRRAK ++ +R Sbjct: 71 RHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERS 130 Query: 201 LM--LRNTATADLAHPLDMFLGGAY-YAAPALDPALCV-----HLVPQLPR--------- 243 L+ L + + A + L Y YAAP P C H +P P Sbjct: 131 LLQPLAHLSPAAFSSFLPESTACPYSYAAPP-PPVTCFPHPYSHALPSQPSTGGAFALSH 189 Query: 244 ------PPVLPVP----PMPPRPPMVPMPPRP 265 P + P P P PP PPM+P+ P Sbjct: 190 QSEDWYPTLHPAPAGHLPCPPPPPMLPLSLEP 221 >gi|113204604 aristaless-like homeobox 3 [Homo sapiens] Length = 343 Score = 92.4 bits (228), Expect = 6e-19 Identities = 58/137 (42%), Positives = 75/137 (54%), Gaps = 7/137 (5%) Query: 127 PQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVW 186 P + E + +KRR RT F+ FQL+ELE F ++ YPDV ARE+LA R +LTE RVQVW Sbjct: 141 PDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVW 200 Query: 187 FQNRRAKWKRNQRVLML---RNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPR 243 FQNRRAKW++ +R + RN TA D+ + + P L +L P Sbjct: 201 FQNRRAKWRKRERYGKIQEGRNPFTA----AYDISVLPRTDSHPQLQNSLWASPGSGSPG 256 Query: 244 PPVLPVPPMPPRPPMVP 260 P L P P P M P Sbjct: 257 GPCLVSPEGIPSPCMSP 273 Score = 36.6 bits (83), Expect = 0.042 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 13/84 (15%) Query: 290 RMAPVP-PWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPL 348 R+ P P P+ PP P P P + P PP GP + R P P+ P Sbjct: 10 RVGPAPGPYVASGDEPPGPQGTPA-AAPHLHPAPPR--------GPRLTRFPACGPLEPY 60 Query: 349 PPGPPMAPLPPGPPMAPLPPGPPM 372 P P PP + L PGP + Sbjct: 61 LPEPAK---PPAKYLQDLGPGPAL 81 Score = 34.3 bits (77), Expect = 0.21 Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 13/78 (16%) Query: 319 APVPPGPPMARVPPGPPMAR--VPPGPPMAP-----LPPGPPMAP-LPPGPPMAPLPPGP 370 AP GP PGP +A PPGP P L P PP P L P PL P Sbjct: 7 APFRVGPA-----PGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYL 61 Query: 371 PMAPLPPRSHVPHTGLAP 388 P PP ++ G P Sbjct: 62 PEPAKPPAKYLQDLGPGP 79 Score = 33.9 bits (76), Expect = 0.27 Identities = 40/136 (29%), Positives = 47/136 (34%), Gaps = 24/136 (17%) Query: 253 PPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPP-GPRMAPVPPWPPMAPVPPWPPMAP 311 P P V PP P A P + P PP GPR+ P P+ P P P P Sbjct: 13 PAPGPYVASGDEPP-GPQGTPAAAP---HLHPAPPRGPRLTRFPACGPLEPYLPEPAKPP 68 Query: 312 VPTGPPMAPVPPGPPM--ARVPPGPPMARVPPGP----PMAPLP------PGPPMAPLPP 359 + + PGP + GP A P PL GP P Sbjct: 69 AKY---LQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSP 125 Query: 360 GPPMA----PLPPGPP 371 GP +A PL PG P Sbjct: 126 GPCLASLHLPLSPGLP 141 Score = 32.7 bits (73), Expect = 0.60 Identities = 30/117 (25%), Positives = 42/117 (35%), Gaps = 18/117 (15%) Query: 244 PPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPP 296 P + P PP PR + P P+ P P PP + + PGP + P Sbjct: 36 PHLHPAPPRGPR--LTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEA 93 Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPP 353 + +P + G P GP + PGP +A + PL PG P Sbjct: 94 EEKTSKAASFPQLPLDCRGGPR----DGPSNLQGSPGPCLASL-----HLPLSPGLP 141 Score = 30.8 bits (68), Expect = 2.3 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 13/76 (17%) Query: 310 APVPTGPPMAPVPPGPPMAR--VPPGP---PMA--RVPPGPPMAP-LPPGPPMAPLPPGP 361 AP GP PGP +A PPGP P A + P PP P L P PL P Sbjct: 7 APFRVGPA-----PGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYL 61 Query: 362 PMAPLPPGPPMAPLPP 377 P PP + L P Sbjct: 62 PEPAKPPAKYLQDLGP 77 >gi|11056038 visual system homeobox 1 isoform a [Homo sapiens] Length = 365 Score = 91.7 bits (226), Expect = 1e-18 Identities = 49/112 (43%), Positives = 65/112 (58%), Gaps = 2/112 (1%) Query: 89 PPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRR-RTAFT 147 P P PP L +Q++ + T+ E Q + P +RK+RR RT FT Sbjct: 114 PEPAAPLAPSRPPPALG-RQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFT 172 Query: 148 QFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQR 199 QL+ELE F E+ YPDV ARE LA + L EDR+QVWFQNRRAKW++ ++ Sbjct: 173 AHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224 Score = 33.5 bits (75), Expect = 0.35 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 17/116 (14%) Query: 274 APVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPG 333 A VP GS P G + + P P P GP +AP P GP + G Sbjct: 16 ALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAVAPCP-GPGL----DG 70 Query: 334 PPMAR--VPPG----------PPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377 +AR +P G PP A P +A +P PP P P P PP Sbjct: 71 SSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPP 126 Score = 29.3 bits (64), Expect = 6.7 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 6/91 (6%) Query: 251 PMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMA--PVPPG-PRMAPVPPWPPMAPVPPWP 307 P P P P +AP P P GS +A +P G + PP A P Sbjct: 44 PAPAGPGQGSGCEGPAVAPCP--GPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL 101 Query: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMAR 338 +A VP PP P P P+A P P + R Sbjct: 102 LLADVPFLPPRGP-EPAAPLAPSRPPPALGR 131 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 90.9 bits (224), Expect = 2e-18 Identities = 55/174 (31%), Positives = 85/174 (48%), Gaps = 15/174 (8%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRM------APVPPGP 289 P P P LP P P + P P P++P P PM+P P SR+ +P+ P P Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612 Query: 290 RMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLP 349 +P+ P P + + P P +P+ P +P+ P P ++R+ P P ++R+ P P +PL Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672 Query: 350 PGPPMAPLPPGPPMAPLPPGP---PMAPLP---PRSHVPHTGLAPVHITWAPVI 397 P P +P P P + L P P P +P P P S P L + + +P++ Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726 Score = 89.4 bits (220), Expect = 5e-18 Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVPPGPRMAPVP 295 P P P P+ P P + P P P++P P PM+P P SR++P+P R++P P Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666 Query: 296 PWPPMAPVPPWPPMAPVP----TGPPMAPVPPGPPMARVPPGPP-----MARVPPGPPMA 346 P++P P P +P P PP P PP P PP M+ P+ Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726 Query: 347 PLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHV 381 PLP P + P GP ++P P P ++P P H+ Sbjct: 727 PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761 Score = 84.7 bits (208), Expect = 1e-16 Identities = 55/177 (31%), Positives = 74/177 (41%), Gaps = 27/177 (15%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVPPGPRMAPVP 295 P P P P+ P P + P P++P P P++P P SR++P P M+P P Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639 Query: 296 PWPPMAPVPPWPPMAPVPT----GPPMAPVPPGPPMARVPPGPP--MARVPPGPPMAPLP 349 PM+P P ++P+P PP P PP P PP +R+ P P +P Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699 Query: 350 PGPPMAPLPPGP------------PMAPLPPGPPMAP------LPPRSHVPHTGLAP 388 P P +P P P P+ PLP P + P L PR PH P Sbjct: 700 PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP 756 Score = 83.6 bits (205), Expect = 3e-16 Identities = 53/165 (32%), Positives = 71/165 (43%), Gaps = 27/165 (16%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPM-----------PPRP----PIAPMPPMAPVPPGSRMA 283 P P P P+ P P P P+ PP P P++P P +P+ P + Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552 Query: 284 PVPPGPRMAPVPPWPP---MAPVPPWPPMAPVPTGPPMAPVPPG----PPMARVPPGPPM 336 P+ P P P P P ++P P PM+P P PM+P P PP P PP Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612 Query: 337 ARVPPGPP-----MAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLP 376 P PP ++P P PM+P P PM+P P ++PLP Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657 Score = 83.2 bits (204), Expect = 4e-16 Identities = 74/301 (24%), Positives = 119/301 (39%), Gaps = 23/301 (7%) Query: 87 EEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAF 146 EE PL+ P ++ P E + PP+ + P P E P + PPE R F Sbjct: 550 EESPLSPPPEELPTSPPPEASR-LSPPPEESPMSPPPEESPMSP----PPEASR----LF 600 Query: 147 TQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNT 206 F+ L +ES ++ A+RL+ + + + V L Sbjct: 601 PPFEESPLSPPPEESP----LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656 Query: 207 ATADLAHPL--DMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPR 264 P + L +P P L P P P P P P PP Sbjct: 657 PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP----PPE 712 Query: 265 PPIAPMP----PMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320 + +P P+ P+P ++ P GP ++P P P ++P P P ++P P ++P Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772 Query: 321 VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSH 380 P P + VP P ++ GP ++P P ++P P ++P+P P ++P P SH Sbjct: 773 QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH 832 Query: 381 V 381 + Sbjct: 833 L 833 Score = 81.6 bits (200), Expect = 1e-15 Identities = 50/177 (28%), Positives = 78/177 (44%), Gaps = 27/177 (15%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVP------PGP 289 P P P V + P+P + P P P++P P P +P P SR++P P P P Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702 Query: 290 RMAPVPPWP------------PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMA 337 +P P P P+ P+P P + P GP ++P P P ++ P P ++ Sbjct: 703 EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762 Query: 338 RVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLP------PRSHVPHTGLAP 388 P ++P P P + +P P ++P GP ++P P P++ PH P Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819 Score = 80.9 bits (198), Expect = 2e-15 Identities = 49/152 (32%), Positives = 73/152 (48%), Gaps = 14/152 (9%) Query: 242 PRPPVL--PVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVPPGPRMAPVPP 296 P P L P+ P P P+ P P++P P P +P P SR++P P M+P P Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586 Query: 297 WPPMAP-------VPPWP--PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAP 347 PM+P PP+ P++P P P++P P ++ P PM+ P PM+P Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646 Query: 348 LPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRS 379 P ++PLP ++P P P++P P S Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678 Score = 77.8 bits (190), Expect = 2e-14 Identities = 55/178 (30%), Positives = 74/178 (41%), Gaps = 21/178 (11%) Query: 225 AAPALDPALCVHL---VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPP 278 A L+P L L +P LP P P+ P P P P P ++P P P +P+P Sbjct: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPE 481 Query: 279 G---------SRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGP-PMAPVPPGPPMA 328 S ++P P ++P P P +P+ P P + P P P PP Sbjct: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541 Query: 329 RVPPGPPMARVPPGPPMAPLPPGPP-----MAPLPPGPPMAPLPPGPPMAPLPPRSHV 381 P PP P PP LP PP ++P P PM+P P PM+P P S + Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599 Score = 69.7 bits (169), Expect = 4e-12 Identities = 50/182 (27%), Positives = 74/182 (40%), Gaps = 35/182 (19%) Query: 230 DPALCV-----HLVPQLPRPPVLPVP------PMPPRPPMVPMPPRP------------P 266 +P LC HL P+ P + P P P P + P P P P Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790 Query: 267 IAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPP--- 323 A P ++P P ++P P ++PVP P ++P P ++P P ++P P Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850 Query: 324 -GPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPL--------PPGPPMAP 374 P + + P P + P P P P P+ P P P ++PL P PP++P Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910 Query: 375 LP 376 LP Sbjct: 911 LP 912 Score = 68.2 bits (165), Expect = 1e-11 Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 4/148 (2%) Query: 231 PALCVHLVPQL-PRPPVLPVPPMPPRPPMVPMPPRPPIAPM---PPMAPVPPGSRMAPVP 286 P L + PQL PR + P P P + P P P ++P P ++P P + VP Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783 Query: 287 PGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMA 346 P ++P P ++P P ++P P ++PVP P ++ P ++ P ++ Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843 Query: 347 PLPPGPPMAPLPPGPPMAPLPPGPPMAP 374 P P ++P PP++P P PP P Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEP 871 Score = 64.3 bits (155), Expect = 2e-10 Identities = 55/187 (29%), Positives = 73/187 (39%), Gaps = 42/187 (22%) Query: 236 HLVPQLPRPPVLPVPPMPPRPP-MVPMPPRPPIAPMPPMAPVPP--GSRMAPVPPGPRMA 292 HL P+L +PP+ P P PP P P P P+ P P + P G P P ++ Sbjct: 850 HLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLS 909 Query: 293 PVPPWPPMAPV--PPWPP--MAPVPTGPPMAPV--------------------------- 321 P+P P++P P P M P P PP++P+ Sbjct: 910 PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP 969 Query: 322 --PPGPPMARVPPGPP----MARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPL 375 P P+ P PP P PPM LPP P +P+ P P+ P P +PL Sbjct: 970 ESPLAAPILETPISPPPEANCTDPEPVPPMI-LPPSPG-SPVGPASPILMEPLPPQCSPL 1027 Query: 376 PPRSHVP 382 S VP Sbjct: 1028 LQHSLVP 1034 Score = 58.2 bits (139), Expect = 1e-08 Identities = 57/194 (29%), Positives = 74/194 (38%), Gaps = 53/194 (27%) Query: 236 HLVPQL------PRP------PVLPVPPMPPRPPMVPMPPRPPIAPMP-PMAPVPPGSRM 282 HL PQ PRP P L PP+ PRP P P AP P+ P P + Sbjct: 832 HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL 891 Query: 283 APVPPGPRMAPVPPWPPMAPVPPWPP-------------MAPVPTGPPMAPV-----PP- 323 +P+ P ++ P PP++P+P P M P P PP++P+ PP Sbjct: 892 SPLLGEPALSE-PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPA 950 Query: 324 --------------GPPMARVPPGPPMARVPPGPP-----MAPLPPGPPMAPLPPGPPMA 364 G P P+ P PP P P P + P PG P+ Sbjct: 951 LSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVG 1010 Query: 365 PLPPGPPMAPLPPR 378 P P M PLPP+ Sbjct: 1011 PASP-ILMEPLPPQ 1023 Score = 56.2 bits (134), Expect = 5e-08 Identities = 50/176 (28%), Positives = 72/176 (40%), Gaps = 33/176 (18%) Query: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPRPP----------MVPMPPRPPIAPM------ 270 P+L P L + + PP+ P+P P P M P P PP++P+ Sbjct: 889 PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948 Query: 271 PPMAPV-----PPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGP 325 P ++P+ P G++ P P AP+ P++P P P P P + P PG Sbjct: 949 PALSPLGELEYPFGAKGDSDPESPLAAPILE-TPISPPPEANCTDPEPVPPMILPPSPGS 1007 Query: 326 PMARVPPGPPMARVPPGPPMAPL------PPGPPMAPLPPGPPMAPLPPGPPMAPL 375 P V P P+ P P +PL P P P PP PL P++P+ Sbjct: 1008 P---VGPASPILMEPLPPQCSPLLQHSLVPQNSP--PSQCSPPALPLSVPSPLSPI 1058 Score = 55.1 bits (131), Expect = 1e-07 Identities = 36/102 (35%), Positives = 42/102 (41%), Gaps = 21/102 (20%) Query: 287 PGPRMAPV--------PPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMAR 338 PGP+ P+ P PP P PP + TGP + PV P PP P + Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPP----GALSTGPVLGPVHPTPP-------PSSPQ 4315 Query: 339 VPPGPPMAPLPPG--PPMAPLPPGPPMAPLPPGPPMAPLPPR 378 P P P P P A LPP P P P GP + P P R Sbjct: 4316 EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357 Score = 52.0 bits (123), Expect = 1e-06 Identities = 83/338 (24%), Positives = 114/338 (33%), Gaps = 50/338 (14%) Query: 81 EPEQQQEEPPLTKPEQQQEEPPLLEL-------------KQEQEEPPQTTVE-----GPQ 122 +P Q +PPL P QQQ++ LL E P + G Q Sbjct: 4085 QPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQ 4144 Query: 123 PAEGPQTAEGPQPP--ERKRRRRTAFTQFQ----LQELENFFDESQYPDVVARERLAARL 176 P Q GPQ P ER + T + LQ + P V +L A+L Sbjct: 4145 PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTV---GQLRAQL 4201 Query: 177 NLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVH 236 + + ++ Q +LM R + + +P C Sbjct: 4202 QGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQP 4261 Query: 237 LVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 + P P P+ + P RP PP P PPG+ + GP + PV P Sbjct: 4262 QLGGFPGPQTGPLQELGAGP-------RPQ---GPPRLPAPPGA----LSTGPVLGPVHP 4307 Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPG---PP 353 PP P P P P P + + P A++PP P P GP + P PPG P Sbjct: 4308 TPP--PSSPQEPKRPSQLPSPSSQL---PTEAQLPPTHPGTPKPQGPTLEP-PPGRVSPA 4361 Query: 354 MAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHI 391 A L L P P L + L P H+ Sbjct: 4362 AAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHL 4399 Score = 51.2 bits (121), Expect = 2e-06 Identities = 46/159 (28%), Positives = 59/159 (37%), Gaps = 19/159 (11%) Query: 240 QLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPG-PRMAPVPPWP 298 +L P V P P + P P + P P PP +AP PP P + + Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP----PPAQALAPSPPSHPDI-----FR 2370 Query: 299 PMAPVPPW--PPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPP-----MAPLPPG 351 P + P+ PP+ P P PP PP R P P +RVP P +PL P Sbjct: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCALPP--RSLPSDPFSRVPASPQSQSSSQSPLTPR 2428 Query: 352 PPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVH 390 P A P+ P P PP AP+H Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLH 2467 Score = 50.4 bits (119), Expect = 3e-06 Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 4/131 (3%) Query: 258 MVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPP 317 M P P P P+ G ++ P P +P PP P PP PT PP Sbjct: 404 MQPKEPGPLQCEAKPLGKA--GVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP 461 Query: 318 MAPVPPGPPMARVPPGPPMARVPPGPPM--APLPPGPPMAPLPPGPPMAPLPPGPPMAPL 375 PP +P P + P+ +PL P P +PL P P +P P Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521 Query: 376 PPRSHVPHTGL 386 PP P L Sbjct: 522 PPEESPPSPAL 532 Score = 49.3 bits (116), Expect = 6e-06 Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 6/139 (4%) Query: 250 PPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPP----GPRMAPVPPWPPMAPVPP 305 P P V +P + M P PG P G ++ P P +P Sbjct: 381 PTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL 440 Query: 306 WPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPM--APLPPGPPM 363 PP P PP P PP PP +P P L P+ +PL P P Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500 Query: 364 APLPPGPPMAPLPPRSHVP 382 +PL P P +P P P Sbjct: 501 SPLSPPPESSPFSPLEESP 519 Score = 47.4 bits (111), Expect = 2e-05 Identities = 43/139 (30%), Positives = 52/139 (37%), Gaps = 18/139 (12%) Query: 237 LVPQLPRPPVLPVPPMPPRPPMVPMP-------PRPPIAPMPPMAPVPPGSRMAPVP--- 286 L PQ P PP + P PP P + P +PP+ P P P PP S A P Sbjct: 2347 LRPQEP-PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ--PPPPESCCALPPRSL 2403 Query: 287 PGPRMAPVPPWPP-----MAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPP 341 P + VP P +P+ P P A P+ P P PP P +R P Sbjct: 2404 PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463 Query: 342 GPPMAPLPPGPPMAPLPPG 360 P P P PP G Sbjct: 2464 APLHKPPRPQPPEVAFKAG 2482 Score = 47.0 bits (110), Expect = 3e-05 Identities = 54/182 (29%), Positives = 65/182 (35%), Gaps = 22/182 (12%) Query: 219 LGGAYYAAPALDPALCVHLVPQL-PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAP-- 275 LGG P + A Q+ P+ P L + P P PP +AP PP P Sbjct: 2316 LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP-------PPAQALAPSPPSHPDI 2368 Query: 276 VPPGSRMAPV---PPGPRMAPVPPWPPMAPVP---PWPPMAPVPTGPP-----MAPVPPG 324 PGS P P PR P PP A P P P + VP P +P+ P Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR 2428 Query: 325 PPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHT 384 P A P+ P PP P + P P P P PP S + HT Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGS-LAHT 2487 Query: 385 GL 386 L Sbjct: 2488 SL 2489 Score = 42.0 bits (97), Expect = 0.001 Identities = 69/273 (25%), Positives = 83/273 (30%), Gaps = 99/273 (36%) Query: 206 TATADLAHPLDMFLGGAYYAAPALDPA--LCVHLVPQLP-----RPPVLPVPPMPPRPPM 258 T A L+ D FL + P D L + L PQ+P + P P P P Sbjct: 2130 TTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRF 2189 Query: 259 VPMPPRPPIAPMPPMAPVPP---GSRMAP----------VPPG-PRMAPVPPWPPMAPVP 304 PP P P P AP P G+ P PPG PR P P P + P Sbjct: 2190 PTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249 Query: 305 PWPPMAPVPTGP---------PMAPVPP----------------------GPP------- 326 P VP P P+ PP GPP Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDS 2309 Query: 327 ----------------MARVPPGPPMARVPPGPPMAPL-----PPGPPMAPLPPG----- 360 + + P P ++V P P L PP +AP PP Sbjct: 2310 PSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF 2369 Query: 361 -----------PPMAPLPPGPP---MAPLPPRS 379 PP+ P P PP LPPRS Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS 2402 Score = 41.6 bits (96), Expect = 0.001 Identities = 36/114 (31%), Positives = 40/114 (35%), Gaps = 5/114 (4%) Query: 261 MPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW--PPMAPVP-PWPPMAPVPTGPP 317 +PP+P PP A P +P P + PP VP P P PP Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165 Query: 318 MAP--VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPG 369 P VP P P P R P PP P P P AP P A PG Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219 Score = 41.2 bits (95), Expect = 0.002 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%) Query: 239 PQLPRPPVLPVPPMPPRPPMVPMP--PRPPIAPMPPMAPVPPGSRMAPVPPGPRMAP 293 P+ P PP P+ P P PP P+ P P+A P +P+P S P PR P Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967 Score = 40.4 bits (93), Expect = 0.003 Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 10/62 (16%) Query: 334 PPMARVPPGPPMAPLPPGPPMAPL----------PPGPPMAPLPPGPPMAPLPPRSHVPH 383 PP PP P+AP P PP PL PP P PL P A PR+ P Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969 Query: 384 TG 385 G Sbjct: 4970 EG 4971 Score = 39.3 bits (90), Expect = 0.006 Identities = 40/139 (28%), Positives = 53/139 (38%), Gaps = 13/139 (9%) Query: 245 PVL--PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAP------VPP 296 P+L P+ P P P P P I P P +PV P S + P P+ +P VP Sbjct: 976 PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQ 1035 Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAP 356 P P PP P+ P++P+ ++ M P P +P Sbjct: 1036 NSP--PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSP 1093 Query: 357 LPPGPPMAPLP-PGPPMAP 374 LP PM L P P AP Sbjct: 1094 LP--SPMGDLSCPAPSPAP 1110 Score = 38.5 bits (88), Expect = 0.011 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 8/67 (11%) Query: 298 PPMAPVPPWPPMAPVPTGPPMAPVP--PGPPMARVP-PGP-PMARVP----PGPPMAPLP 349 PP P PP P+AP P PP P+ P P+A P P P P+A P P P P Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969 Query: 350 PGPPMAP 356 G P Sbjct: 4970 EGEDSRP 4976 Score = 36.6 bits (83), Expect = 0.042 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 8/79 (10%) Query: 247 LPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP-PMAPVP- 304 L V + PP P PP P+AP P P P + +P P P P P P+A P Sbjct: 4901 LDVRQLSAPPPEEPSPPPSPLAPSPASPPTEP---LVELPTEPLAEPPVPSPLPLASSPE 4957 Query: 305 ---PWPPMAPVPTGPPMAP 320 P P P G P Sbjct: 4958 SARPKPRARPPEEGEDSRP 4976 Score = 35.8 bits (81), Expect = 0.071 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Query: 271 PPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP-PMAPVPTGPPMAPVPPG---PP 326 PP P PP S +AP P P P P+ +P P PVP+ P+A P P Sbjct: 4910 PPEEPSPPPSPLAPSPASP------PTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963 Query: 327 MARVPPGPPMARVP 340 AR P +R P Sbjct: 4964 RARPPEEGEDSRPP 4977 Score = 34.7 bits (78), Expect = 0.16 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 4/70 (5%) Query: 250 PPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPP--WP 307 PP P PP P+ P P P P+ +P + PP P P+ P A P P Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELP--TEPLAEPPVPSPLPLASSPESARPKPRARP 4967 Query: 308 PMAPVPTGPP 317 P + PP Sbjct: 4968 PEEGEDSRPP 4977 Score = 32.7 bits (73), Expect = 0.60 Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 16/83 (19%) Query: 320 PVPPGPPMARVPPGPPMA----RVP-PGPPMAPLPPGPPM-------APLPPGPPMAPLP 367 P PGP + R G P+A R+P PG P+ P P GP GP P P Sbjct: 2838 PSTPGPELGRQALGSPLAGISTRLPGPGEPV-PGPAGPAQFIELRHNVQKGLGPGGTPFP 2896 Query: 368 -PGPPMAP-LPPRSHVPHTGLAP 388 GPP P P S PH LAP Sbjct: 2897 GQGPPQRPRFYPVSEDPHR-LAP 2918 Score = 32.3 bits (72), Expect = 0.79 Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 1/46 (2%) Query: 350 PGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAP 395 PGP PL P P GPP P PP + L PVH T P Sbjct: 4267 PGPQTGPLQE-LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP 4311 Score = 32.3 bits (72), Expect = 0.79 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 7/73 (9%) Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPP- 323 PP P PP +P+ P P P + P P+A PP P P+ + P A P Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVEL----PTEPLAE-PPVPSPLPLASSPESARPKPR 4964 Query: 324 -GPPMARVPPGPP 335 PP PP Sbjct: 4965 ARPPEEGEDSRPP 4977 Score = 31.6 bits (70), Expect = 1.3 Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 9/77 (11%) Query: 298 PPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPL 357 PP P P PP +P+ P PP P+ +P P PP P PL P A Sbjct: 4909 PP--PEEPSPPPSPLAPSPAS---PPTEPLVELPTEP--LAEPPVPSPLPLASSPESA-- 4959 Query: 358 PPGPPMAPLPPGPPMAP 374 P P P G P Sbjct: 4960 RPKPRARPPEEGEDSRP 4976 Score = 29.3 bits (64), Expect = 6.7 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 4/73 (5%) Query: 243 RPPVLPVPPMPPRPPMVPMPPR--PPIAPMPPMAPVPPGSR--MAPVPPGPRMAPVPPWP 298 R P LP P MP +PP + R P +A + + G A + P PV Sbjct: 3321 RQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQK 3380 Query: 299 PMAPVPPWPPMAP 311 PM +PP M P Sbjct: 3381 PMGTMPPSMCMKP 3393 Score = 29.3 bits (64), Expect = 6.7 Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 17/73 (23%) Query: 83 EQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQ-----------------TTVEGPQPAE 125 +QQQ++ L + +QQQ + +L+Q+Q++ Q T+ PQ + Sbjct: 3932 QQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQ 3991 Query: 126 GPQTAEGPQPPER 138 Q A GP P + Sbjct: 3992 QQQVALGPGMPAK 4004 Score = 29.3 bits (64), Expect = 6.7 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 2/36 (5%) Query: 352 PPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLA 387 PP P P PP +PL P P P P +P LA Sbjct: 4909 PP--PEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942 >gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] Length = 483 Score = 90.5 bits (223), Expect = 2e-18 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%) Query: 98 QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145 +EE LE K+ E E+ + +++G + A PQ+ EG P +RK+RR RT Sbjct: 165 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 224 Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205 FT QL+ELE F+ + YPD+ RE LA R LTE RVQVWF NRRA+W R Sbjct: 225 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 275 Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264 A A+ + + G + P P L + + + +P +P P + P Sbjct: 276 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 333 Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305 PP P P S A P R + VPP P P+ P Sbjct: 334 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 381 >gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] Length = 403 Score = 90.5 bits (223), Expect = 2e-18 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%) Query: 98 QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145 +EE LE K+ E E+ + +++G + A PQ+ EG P +RK+RR RT Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225 Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205 FT QL+ELE F+ + YPD+ RE LA R LTE RVQVWF NRRA+W R Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276 Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264 A A+ + + G + P P L + + + +P +P P + P Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334 Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305 PP P P S A P R + VPP P P+ P Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382 >gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] Length = 407 Score = 90.5 bits (223), Expect = 2e-18 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%) Query: 98 QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145 +EE LE K+ E E+ + +++G + A PQ+ EG P +RK+RR RT Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225 Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205 FT QL+ELE F+ + YPD+ RE LA R LTE RVQVWF NRRA+W R Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276 Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264 A A+ + + G + P P L + + + +P +P P + P Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334 Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305 PP P P S A P R + VPP P P+ P Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382 >gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] Length = 505 Score = 90.5 bits (223), Expect = 2e-18 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%) Query: 98 QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145 +EE LE K+ E E+ + +++G + A PQ+ EG P +RK+RR RT Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225 Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205 FT QL+ELE F+ + YPD+ RE LA R LTE RVQVWF NRRA+W R Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276 Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264 A A+ + + G + P P L + + + +P +P P + P Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334 Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305 PP P P S A P R + VPP P P+ P Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382 >gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] Length = 484 Score = 90.5 bits (223), Expect = 2e-18 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%) Query: 98 QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145 +EE LE K+ E E+ + +++G + A PQ+ EG P +RK+RR RT Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225 Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205 FT QL+ELE F+ + YPD+ RE LA R LTE RVQVWF NRRA+W R Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276 Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264 A A+ + + G + P P L + + + +P +P P + P Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334 Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305 PP P P S A P R + VPP P P+ P Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382 >gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] Length = 479 Score = 90.5 bits (223), Expect = 2e-18 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%) Query: 98 QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145 +EE LE K+ E E+ + +++G + A PQ+ EG P +RK+RR RT Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225 Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205 FT QL+ELE F+ + YPD+ RE LA R LTE RVQVWF NRRA+W R Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276 Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264 A A+ + + G + P P L + + + +P +P P + P Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334 Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305 PP P P S A P R + VPP P P+ P Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 89.7 bits (221), Expect = 4e-18 Identities = 63/163 (38%), Positives = 71/163 (43%), Gaps = 33/163 (20%) Query: 242 PRPPVLPVPPM------PPR--PPMVPMPPRPPIAPMP---PMAPVPPGSRMAPV----- 285 P+PP+ P PP PP+ PP P P +PP P P P PP PV Sbjct: 56 PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115 Query: 286 ---------PPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPP-MAPVPPGPPMARVPPGPP 335 PP AP P PP + PP P PT PP + PPG P PP PP Sbjct: 116 GPAPGVGSAPPASSSAP-PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP----PPTPP 170 Query: 336 MARVPPGPPMAPLPPGPPMA-PLP-PGPPMAPLPPGPPMAPLP 376 + VP PP A PP PP A P P PGP P P GP +P Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP 213 Score = 84.3 bits (207), Expect = 2e-16 Identities = 61/155 (39%), Positives = 67/155 (43%), Gaps = 21/155 (13%) Query: 236 HLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAP--------VPP 287 H P P+P PP PP+ P+ + P P P + PP S AP PP Sbjct: 85 HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP-GPAPGVGSAPPASSSAPPATPPTSGAPP 143 Query: 288 GPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVP---PGPP 344 G P P PP V PP AP PT PP + VP PP A PP PP A VP PGP Sbjct: 144 GSGPGPTPTPPPA--VTSAPPGAPPPT-PPSSGVPTTPPQAGGPP-PPPAAVPGPGPGPK 199 Query: 345 MAPLPPGP-----PMAPLPPGPPMAPLPPGPPMAP 374 P P GP P P P G P P G P P Sbjct: 200 QGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234 Score = 79.0 bits (193), Expect = 7e-15 Identities = 62/156 (39%), Positives = 69/156 (44%), Gaps = 23/156 (14%) Query: 255 RPPMVPMP----PRPPIAPMPP--MAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPP 308 R PM P P P+PPI P PP PP + P P P P P P PP PP Sbjct: 44 RGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPP 103 Query: 309 M----APVPTGPPMAP-VPPGPP-MARVPPG-PPMARVPP--GPPMAPLPP-----GPPM 354 V GP AP V PP + PP PP + PP GP P PP PP Sbjct: 104 QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPG 163 Query: 355 APLPPGPPMAPLPPGPPMA--PLPPRSHVPHTGLAP 388 AP PP PP + +P PP A P PP + VP G P Sbjct: 164 AP-PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198 Score = 61.2 bits (147), Expect = 2e-09 Identities = 47/144 (32%), Positives = 55/144 (38%), Gaps = 37/144 (25%) Query: 277 PPGSRM----APVPPGPRMA----PVPPWPPMAPVPPWPPMAPVPTGPP--MAPVPPGPP 326 PPG + P+ PGP + P+PP PP PP P P PP P P P Sbjct: 35 PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPH 94 Query: 327 MARVPPGPP-----------------MARVPPG--------PPMAPLPPGPPMAPLP-PG 360 + PP PP + PP PP + PPG P P P Sbjct: 95 QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPP 154 Query: 361 PPMAPLPPGPPMAPLPPRSHVPHT 384 P + PPG P P PP S VP T Sbjct: 155 PAVTSAPPGAP-PPTPPSSGVPTT 177 Score = 47.0 bits (110), Expect = 3e-05 Identities = 43/126 (34%), Positives = 46/126 (36%), Gaps = 29/126 (23%) Query: 242 PRPPVLPVPP--MPPRPPMVPMPPRPPIA---PMPPMAPVPPGSRMAPVPPGPRMAPVPP 296 P P V PP PP PP +P PP A P PP A PG PGP+ P P Sbjct: 153 PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG-------PGPKQGPGPG 205 Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPP----GPPMARVPPGPP------MA 346 P +P P P G P P G P PP G P PP Sbjct: 206 GPKGGKMPG----GPKPGGGPGLSTPGGHPK---PPHRGGGEPRGGRQHHPPYHQQHHQG 258 Query: 347 PLPPGP 352 P P GP Sbjct: 259 PPPGGP 264 Score = 43.1 bits (100), Expect = 4e-04 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 9/100 (9%) Query: 40 GGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQ- 98 GG + P G N G G P + P QQQ++PP +P QQ Sbjct: 23 GGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82 Query: 99 ---EEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135 + PP + Q+Q+ PP PQ + P A+GP P Sbjct: 83 PPHQPPPHPQPHQQQQPPPP-----PQDSSKPVVAQGPGP 117 Score = 36.2 bits (82), Expect = 0.055 Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 3/78 (3%) Query: 322 PPGPPMA--RVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRS 379 PPG + R P GP + P PP+ P PP PP P PP P P P+ Sbjct: 35 PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP-PHQPPPHPQP 93 Query: 380 HVPHTGLAPVHITWAPVI 397 H P + PV+ Sbjct: 94 HQQQQPPPPPQDSSKPVV 111 >gi|122937321 UNC homeobox [Homo sapiens] Length = 531 Score = 89.7 bits (221), Expect = 4e-18 Identities = 94/323 (29%), Positives = 117/323 (36%), Gaps = 83/323 (25%) Query: 135 PPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKW 194 P ++RR RT FT +QL+ELE F+ES YPDV RE LA RL+L E RVQVWFQNRRAKW Sbjct: 101 PGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKW 160 Query: 195 KRNQRVL------MLRNTATADLAHPLD-----------------------MFLGGAYYA 225 ++ + + T P+D + G + Sbjct: 161 RKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLH 220 Query: 226 APALDPALCVHLVPQLPRPP----VLPVPPMPPRP----PMVPMPPRPPIAPMPPMAPVP 277 +P L +H P + P PP PP P P AP PP P Sbjct: 221 SPG---GLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPA 277 Query: 278 PGSRMAPVPPGPRMAPVPPWPPMAPVP-------PWPPMAPVPTG----PPMAP------ 320 PG+ P R P P P P +A V G P +P Sbjct: 278 PGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESL 337 Query: 321 VPPGPPMARVPPGPPMARV-----PPGPPMAP---------------LPPG--PPMAPLP 358 + PP + A PG P AP P G P A L Sbjct: 338 LSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALK 397 Query: 359 PGPPMAP----LPPGPPMAPLPP 377 G + P PP P + P PP Sbjct: 398 GGAGLEPAPKDAPPAPAVPPAPP 420 Score = 46.6 bits (109), Expect = 4e-05 Identities = 83/331 (25%), Positives = 98/331 (29%), Gaps = 55/331 (16%) Query: 66 SVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAE 125 S PS D D GGGG PE + PP K EPP P Sbjct: 229 SAPSSDSD-SGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYP 287 Query: 126 GPQTAEGPQP-PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARL-NLTEDRV 183 ++ GPQP P R + A V A ER AA L + V Sbjct: 288 SQRSGAGPQPRPGRPADKDAASC-------------GPGAAVAAVERGAAGLPKASPFSV 334 Query: 184 QVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLG-----------GAYYAAPALDPA 232 + + + K + A A A LD G G + P P Sbjct: 335 ESLLSDSPPRRKA-------ASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPL 387 Query: 233 LCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292 LVPQ + P P P P P + P PP GP A Sbjct: 388 --GFLVPQAALKGGAGLEPAPKDAP-----------PAPAVPPAPPAQASFGAFSGPGGA 434 Query: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLP-PG 351 P + +P P AP P P + A G A P P P P Sbjct: 435 PDSAFARRSPDAVASPGAPAPAPAPFRDLASAA--ATEGGGGDCADAGTAGPAPPPPAPS 492 Query: 352 PPMAPLPPGPPMAPL-----PPGPPMAPLPP 377 P P PP P P PG P PP Sbjct: 493 PRPGPRPPSPAEEPATCGVPEPGAAAGPSPP 523 Score = 33.5 bits (75), Expect = 0.35 Identities = 38/137 (27%), Positives = 44/137 (32%), Gaps = 46/137 (33%) Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPP-GPPMARVPPGPP------------------MA 337 +P P+ P A + G + P P PP VPP PP A Sbjct: 381 YPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFA 440 Query: 338 RVPPGPPMAPLPPGPPMAPL-----------------------PPGPPMAPLP-PGP-PM 372 R P +P P P AP P PP AP P PGP P Sbjct: 441 RRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPP 500 Query: 373 APL--PPRSHVPHTGLA 387 +P P VP G A Sbjct: 501 SPAEEPATCGVPEPGAA 517 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.137 0.443 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,441,015 Number of Sequences: 37866 Number of extensions: 2706449 Number of successful extensions: 124177 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1631 Number of HSP's successfully gapped in prelim test: 1632 Number of HSP's that attempted gapping in prelim test: 19579 Number of HSP's gapped (non-prelim): 35689 length of query: 406 length of database: 18,247,518 effective HSP length: 105 effective length of query: 301 effective length of database: 14,271,588 effective search space: 4295747988 effective search space used: 4295747988 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.