Guide to the Human Genome
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Search of human proteins with 23592228

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like
[Homo sapiens]
         (406 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...   870   0.0  
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...   120   2e-27
gi|160707881 formin 2 [Homo sapiens]                                  116   3e-26
gi|14249119 Rhox homeobox family, member 2 [Homo sapiens]             116   3e-26
gi|153791494 Rhox homeobox family, member 2B [Homo sapiens]           115   5e-26
gi|23943886 Rhox homeobox family, member 1 [Homo sapiens]             109   4e-24
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                    104   2e-22
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                    104   2e-22
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap...   103   2e-22
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                  99   7e-21
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]             99   9e-21
gi|14149760 orthopedia homeobox [Homo sapiens]                         99   9e-21
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    98   1e-20
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 97   3e-20
gi|24497589 aristaless related homeobox [Homo sapiens]                 96   6e-20
gi|4557489 cone-rod homeobox protein [Homo sapiens]                    96   6e-20
gi|7706659 paired related homeobox 2 [Homo sapiens]                    95   1e-19
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    94   3e-19
gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]                93   5e-19
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 92   6e-19
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]          92   1e-18
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    91   2e-18
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                 91   2e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                  91   2e-18
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                  91   2e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                  91   2e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                  91   2e-18
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                   91   2e-18
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    90   4e-18
gi|122937321 UNC homeobox [Homo sapiens]                               90   4e-18

>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score =  870 bits (2248), Expect = 0.0
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 1   MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN 60
           MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN
Sbjct: 1   MESLRGYTHSDIGYRSLAVGEDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENN 60

Query: 61  VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG 120
           VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG
Sbjct: 61  VGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEG 120

Query: 121 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE 180
           PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE
Sbjct: 121 PQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTE 180

Query: 181 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ 240
           DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ
Sbjct: 181 DRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQ 240

Query: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM 300
           LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM
Sbjct: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM 300

Query: 301 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG 360
           APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG
Sbjct: 301 APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPG 360

Query: 361 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF 406
           PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF
Sbjct: 361 PPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACPFF 406


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score =  120 bits (301), Expect = 2e-27
 Identities = 91/306 (29%), Positives = 123/306 (40%), Gaps = 60/306 (19%)

Query: 56  EAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEP-PLLELKQEQEEPP 114
           E +  +G   + P   ++     G EP      PP   P  + E P P    +  +  P 
Sbjct: 62  ERDRRLGARPACPKAPEE-----GSEPSP----PPAPAPAPEYEAPRPYCPKEPGEARPS 112

Query: 115 QTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAA 174
                GP   E  + +E  QP ++ RR RT FT +QL ELE  F++S YPDV +RE LA 
Sbjct: 113 PGLPVGPATGEA-KLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAG 171

Query: 175 RLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALC 234
           ++NL E RVQVWFQNRRAKW+R +++ +                                
Sbjct: 172 KVNLPEVRVQVWFQNRRAKWRRQEKLEVSS------------------------------ 201

Query: 235 VHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPV 294
                +L   P+L     PP   + P+   P     P    +P  S + P  PG     +
Sbjct: 202 ----MKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATAL 257

Query: 295 PPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPM 354
              P        PP   +P      P PP PP    P        P GP + PL P PP 
Sbjct: 258 QSLPGFG-----PPAQSLPAS--YTPPPPPPPFLNSP--------PLGPGLQPLAPPPPS 302

Query: 355 APLPPG 360
            P  PG
Sbjct: 303 YPCGPG 308


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  116 bits (291), Expect = 3e-26
 Identities = 73/170 (42%), Positives = 103/170 (60%), Gaps = 24/170 (14%)

Query: 241  LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP+    +P+PP  P A +PP  P+P G+ + P PP P  A +PP
Sbjct: 942  IPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPP 999

Query: 297  WPPM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM- 345
             PP+  A +PP PP+  A +P  PP+  A +PP PP+  A +PP PP+  A +PP PP+ 
Sbjct: 1000 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1059

Query: 346  -APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
             A +PP PP+  A +PP PP+  A +PP PP+  A +PP   +P  G+ P
Sbjct: 1060 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109



 Score =  115 bits (288), Expect = 7e-26
 Identities = 80/197 (40%), Positives = 111/197 (56%), Gaps = 29/197 (14%)

Query: 219  LGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMP----PRPPMVP---MPPRPPI--AP 269
            L GA    P   P   + L P LP   + P PP+P    P PP +P   +PP PP+  A 
Sbjct: 948  LPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1007

Query: 270  MPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM--APVPPWPPM--APVPTGPPM--APVPP 323
            +PP  P+ PG+ + P PP P  A +PP PP+  A +PP PP+  A +P  PP+  A +PP
Sbjct: 1008 IPPPPPL-PGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065

Query: 324  GPPM--ARVPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM- 372
             PP+  A +PP PP+  A +PP PP+  A +PP PP+    +PP PP+  A +PP PP+ 
Sbjct: 1066 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP 1125

Query: 373  -APLPPRSHVPHTGLAP 388
             A +PP   +P  G+ P
Sbjct: 1126 GAGIPPPPPLPGAGIPP 1142



 Score =  112 bits (280), Expect = 6e-25
 Identities = 80/202 (39%), Positives = 111/202 (54%), Gaps = 29/202 (14%)

Query: 214  PLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMP----PRPPMVP---MPPRPP 266
            PL   L GA    P   P   +   P LP   + P PP+P    P PP +P   +PP PP
Sbjct: 965  PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1024

Query: 267  I--APMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM--APVPPWPPM--APVPTGPPM-- 318
            +  A +PP  P+P G+ + P PP P  A +PP PP+  A +PP PP+  A +P  PP+  
Sbjct: 1025 LPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1082

Query: 319  APVPPGPPM--ARVPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPP 368
            A +PP PP+  A +PP PP+    +PP PP+  A +PP PP+  A +PP PP+  A +PP
Sbjct: 1083 AGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142

Query: 369  GPPM--APLPPRSHVPHTGLAP 388
             PP+    +PP   +P  G+ P
Sbjct: 1143 PPPLPRVGIPPPPPLPGAGIPP 1164



 Score =  112 bits (279), Expect = 8e-25
 Identities = 71/169 (42%), Positives = 98/169 (57%), Gaps = 22/169 (13%)

Query: 241  LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP+    +P PP  P A +PP  P+P G+ + P PP P +   PP
Sbjct: 1052 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGVGIPPP 1110

Query: 297  WP-PMAPVPPWPPM--APVPTGPPM--APVPPGPPMARV--PPGPPM--ARVPPGPPM-- 345
             P P A +PP PP+  A +P  PP+  A +PP PP+ RV  PP PP+  A +PP PP+  
Sbjct: 1111 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPG 1170

Query: 346  APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
            A +PP PP+    +PP PP+    +PP PP+  A +PP   +P  G+ P
Sbjct: 1171 AGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPP 1219



 Score =  111 bits (277), Expect = 1e-24
 Identities = 72/170 (42%), Positives = 99/170 (58%), Gaps = 24/170 (14%)

Query: 241  LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP+    +P PP  P A +PP  P+P G+ + P PP P  A +PP
Sbjct: 1041 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPP 1098

Query: 297  WPPMAPV--PPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPMARV--PPGPPM- 345
             PP+  V  PP PP+  A +P  PP+  A +PP PP+  A +PP PP+ RV  PP PP+ 
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158

Query: 346  -APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
             A +PP PP+  A +PP PP+    +PP PP+    +PP   +P  G+ P
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208



 Score =  110 bits (276), Expect = 2e-24
 Identities = 77/179 (43%), Positives = 106/179 (59%), Gaps = 34/179 (18%)

Query: 242  PRPPVLP---VPPMP----PRPP------MVPMPPRP-PIAPMPPMAPVPPGSRMAPVPP 287
            P PP LP   VP +P    P+PP      M+P PP P P A +PP  P+P G+ + P+PP
Sbjct: 878  PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLP-GAGILPLPP 936

Query: 288  GPRMAPVPPWPPM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--A 337
             P  A +PP PP+  A +PP PP+  A +P  PP+  A +PP PP+  A +PP PP+  A
Sbjct: 937  LPG-AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 995

Query: 338  RVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
             +PP PP+  A +PP PP+  A +PP PP+  A +PP PP+  A +PP   +P  G+ P
Sbjct: 996  GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1054



 Score =  110 bits (276), Expect = 2e-24
 Identities = 70/168 (41%), Positives = 98/168 (58%), Gaps = 22/168 (13%)

Query: 239  PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP 298
            P LP   +LP+PP+P     +P PP  P A +PP  P+P      P+PP    A +PP P
Sbjct: 924  PPLPGAGILPLPPLPGAG--IPPPPPLPGAAIPPPPPLPGAG--IPLPPPLPGAGIPPPP 979

Query: 299  PM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM--A 346
            P+  A +PP PP+  A +P  PP+  A +PP PP+  A +PP PP+  A +PP PP+  A
Sbjct: 980  PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1039

Query: 347  PLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
             +PP PP+  A +PP PP+  A +PP PP+  A +PP   +P  G+ P
Sbjct: 1040 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087



 Score =  110 bits (274), Expect = 3e-24
 Identities = 77/195 (39%), Positives = 110/195 (56%), Gaps = 39/195 (20%)

Query: 231  PALCVHLVPQ--LPRPP------VLPVPP-------MPPRPPM-----VPMPPRPPIAPM 270
            P + V  +P   +P+PP      +LP PP       +PP PP+     +P+PP P  A +
Sbjct: 884  PGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPG-AGI 942

Query: 271  PPMAPVPPGSRMAPVPPGPRMA-PVPPWPPMAPVPPWPPM--APVPTGPPM--APVPPGP 325
            PP  P+ PG+ + P PP P    P+PP  P A +PP PP+  A +P  PP+  A +PP P
Sbjct: 943  PPPPPL-PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001

Query: 326  PM--ARVPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM--A 373
            P+  A +PP PP+  A +PP PP+  A +PP PP+  A +PP PP+  A +PP PP+  A
Sbjct: 1002 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1061

Query: 374  PLPPRSHVPHTGLAP 388
             +PP   +P  G+ P
Sbjct: 1062 GIPPPPPLPGAGIPP 1076



 Score =  110 bits (274), Expect = 3e-24
 Identities = 70/170 (41%), Positives = 99/170 (58%), Gaps = 24/170 (14%)

Query: 241  LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP+    +P PP  P A +PP  P+P G+ + P PP P  A +PP
Sbjct: 1030 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPG-AGIPP 1087

Query: 297  WPPM--APVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM- 345
             PP+  A +PP PP+    +P  PP+  A +PP PP+  A +PP PP+  A +PP PP+ 
Sbjct: 1088 PPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1147

Query: 346  -APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
               +PP PP+  A +PP PP+  A +PP PP+    +PP   +P  G+ P
Sbjct: 1148 RVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP 1197



 Score =  106 bits (264), Expect = 4e-23
 Identities = 73/175 (41%), Positives = 98/175 (56%), Gaps = 30/175 (17%)

Query: 241  LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP+    +P PP  P A +PP  P+P G  + P PP P  A +PP
Sbjct: 1063 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GVGIPPPPPLPG-AGIPP 1120

Query: 297  WPPM--APVPPWPPM--APVPTGPPMAPV--PPGPPM--ARVPPGPPM--ARVPPGPPM- 345
             PP+  A +PP PP+  A +P  PP+  V  PP PP+  A +PP PP+  A +PP PP+ 
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1180

Query: 346  -APLPPGPPM--APLPPGPPM--APLPPGPPM-------APLPPRSHVPHTGLAP 388
               +PP PP+    +PP PP+  A +PP PP+       AP PP    P TG+ P
Sbjct: 1181 GVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP-PPGTGIPP 1234



 Score =  105 bits (262), Expect = 7e-23
 Identities = 70/189 (37%), Positives = 99/189 (52%), Gaps = 28/189 (14%)

Query: 227  PALDPALCVHLVPQLPRPPVLPVPPMP------PRPPMVPMPPRPPIAP---MPPMAPVP 277
            P+  P  C      +P   ++P PP P      P  P   +P  PP+     +PP  P  
Sbjct: 856  PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915

Query: 278  PGSRMAPVP--PGPRMAPVPPWPPMAPVPPWPPM--APVPTGPPM----APVPPGPPMAR 329
            PG+ + P P  PG  + P+PP P  A +PP PP+  A +P  PP+     P+PP  P A 
Sbjct: 916  PGAGIPPPPPLPGAGILPLPPLPG-AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAG 974

Query: 330  VPPGPPM--ARVPPGPPM--APLPPGPPM--APLPPGPPM--APLPPGPPM--APLPPRS 379
            +PP PP+  A +PP PP+  A +PP PP+  A +PP PP+  A +PP PP+  A +PP  
Sbjct: 975  IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1034

Query: 380  HVPHTGLAP 388
             +P  G+ P
Sbjct: 1035 PLPGAGIPP 1043



 Score =  103 bits (258), Expect = 2e-22
 Identities = 66/162 (40%), Positives = 89/162 (54%), Gaps = 22/162 (13%)

Query: 241  LPRPPVLPVPPMPPRPPM----VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP+    +P PP  P A +PP  P+P G+ + P PP PR+   PP
Sbjct: 1096 IPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPRVGIPPP 1154

Query: 297  WP-PMAPVPPWPPM--APVPTGPPM--APVPPGPPM--ARVPPGPPM--ARVPPGPPM-- 345
             P P A +PP PP+  A +P  PP+    +PP PP+    +PP PP+  A +PP PP+  
Sbjct: 1155 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1214

Query: 346  -----APLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVP 382
                 AP PP PP     P PP+ P+  GPP+ P    S +P
Sbjct: 1215 MGIPPAPAPPLPPPGTGIPPPPLLPV-SGPPLLPQVGSSTLP 1255



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 65/162 (40%), Positives = 85/162 (52%), Gaps = 20/162 (12%)

Query: 241  LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMA-PVPPGSRMAPVPP--GPRMAPVPPW 297
            +P PP LP        P + M P PP  P+P M  P  P + +   PP  G  M P PP 
Sbjct: 855  IPSPPPLPCTESSSSMPGLGMVPPPP-PPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913

Query: 298  P-PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPM--ARVPPGPPM----APLPP 350
            P P A +PP PP+     G  + P+PP  P A +PP PP+  A +PP PP+     PLPP
Sbjct: 914  PLPGAGIPPPPPL----PGAGILPLPP-LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968

Query: 351  GPPMAPLPPGPPM--APLPPGPPM--APLPPRSHVPHTGLAP 388
              P A +PP PP+  A +PP PP+  A +PP   +P  G+ P
Sbjct: 969  PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1010



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 47/133 (35%), Positives = 60/133 (45%), Gaps = 25/133 (18%)

Query: 241  LPRPPVLP---VPPMPPRPPM-VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
            +P PP LP   +PP PP P + +P PP  P A +PP  P+P       +PP    AP PP
Sbjct: 1173 IPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG----MGIPP----APAPP 1224

Query: 297  WPPMAPVPPWPPMAPVPTGPPMAP------VPPGPPMARVPPGPPMA------RVPPGPP 344
             PP     P PP+ PV +GPP+ P      +P       +PP  P            G  
Sbjct: 1225 LPPPGTGIPPPPLLPV-SGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSR 1283

Query: 345  MAPLPPGPPMAPL 357
              P+ P  PM PL
Sbjct: 1284 KQPIEPCRPMKPL 1296



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/182 (26%), Positives = 61/182 (33%), Gaps = 35/182 (19%)

Query: 241 LPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVP-----------PGSRMAPVPPGP 289
           L  PPV  +P  PP PP     P+        +   P           P   ++  PP P
Sbjct: 755 LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP 814

Query: 290 RMAPVPPWPPMAPVPPWPPMAPVPTGPPMA-----------PVPPGPPMARVPPGPP-MA 337
            +            PP        T    +           P PP  P        P + 
Sbjct: 815 SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLG 874

Query: 338 RVPPGPPMAPLP----PGPPMAPLPPGPP-----MAPLPPGP-PMAPLPPRSHVPHTGLA 387
            VPP PP  PLP    P  P   +P  PP     M P PP P P A +PP   +P  G+ 
Sbjct: 875 MVPPPPP--PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL 932

Query: 388 PV 389
           P+
Sbjct: 933 PL 934



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 30/121 (24%)

Query: 219  LGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMP-------PRPPMVP----MPPRPPI 267
            L G     P   P + +   P LP   + P PP+P       P PP+ P    +PP PP+
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP-PPL 1237

Query: 268  APM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPP--------------MAPVPPWPPMAP 311
             P+  PP+ P   GS   P P      P PP P                 P+ P  PM P
Sbjct: 1238 LPVSGPPLLP-QVGSSTLPTPQVCGFLP-PPLPSGLFGLGMNQDKGSRKQPIEPCRPMKP 1295

Query: 312  V 312
            +
Sbjct: 1296 L 1296



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 65/280 (23%), Positives = 95/280 (33%), Gaps = 48/280 (17%)

Query: 113 PPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERL 172
           P +  V G   AE  +TA G Q  +R              ++ +F   ++  D+++  + 
Sbjct: 149 PAEARVGGRPIAEDVETAAGAQDGQRTSSGSDT-------DIYSFHSATEQEDLLSDIQQ 201

Query: 173 AARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTA---TADLAHP-----LDMFL----G 220
           A RL   + + Q   Q +  + ++ Q++      A   TA    P     LD FL    G
Sbjct: 202 AIRL---QQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSG 258

Query: 221 GAYYAAPALDPALCVHLVPQLPRPPVLPV--PPMPPRPPMVPMPPRPPIAPMPPMAPVPP 278
           GA  A  + D    +  +  LP         P  PP P  +P+   P +    P A   P
Sbjct: 259 GAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSP 318

Query: 279 GSRMAPVP---PGPRMAPVP-----------------PWPPMAPVPPWPPMAPVPTGPPM 318
            S   P P   PG   A  P                   P  +P   W P   V    P 
Sbjct: 319 SSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAP--EVGEDAPQ 376

Query: 319 APVPPGPPMARVPPGPPMARVP--PGPPMAPLPPGPPMAP 356
                    A+ P  P  A +P  P P      P P + P
Sbjct: 377 RLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITP 416



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 3/41 (7%)

Query: 95  EQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135
           +QQQ++   L+L+Q+Q+   Q  ++G +    P TA  PQP
Sbjct: 206 QQQQQQQLQLQLQQQQQ---QQQLQGAEEPAAPPTAVSPQP 243


>gi|14249119 Rhox homeobox family, member 2 [Homo sapiens]
          Length = 288

 Score =  116 bits (291), Expect = 3e-26
 Identities = 87/258 (33%), Positives = 122/258 (47%), Gaps = 32/258 (12%)

Query: 21  EDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQD-----RE 75
           +D +E+ D    V SL     E+EE+ + +PE GT A   + + G+   +++D     ++
Sbjct: 20  DDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKD 79

Query: 76  GGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135
           GGG   P    E       E        +E   + E+ P      PQ A G     G +P
Sbjct: 80  GGGAGVPGHLWEGDL----EGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVG-----GLEP 130

Query: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195
              ++    AFT  QLQELE  F   Q+P    R RLA  +N+TE  VQ+WF+NRRAKW+
Sbjct: 131 GNAQQPNVHAFTPLQLQELERIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWR 190

Query: 196 RNQRVLMLRN-----------TATADLAHPLDMFLGGA---YYAAPALDPALCVHLVPQL 241
           R+QR LM RN             TA  A    +F+ G    Y+   +   +LC  + P  
Sbjct: 191 RHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPM-PPF 249

Query: 242 PRPPVLPVPPM--PPRPP 257
           P PP LP+P M  PP PP
Sbjct: 250 P-PPSLPLPLMLLPPMPP 266



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)

Query: 302 PVPPWPPMAPVPTGP-PMAPVPPGPPMARVPPGP-PMARVP 340
           P+PP+PP    P+ P P+  +PP PP  +   GP P   VP
Sbjct: 245 PMPPFPP----PSLPLPLMLLPPMPPAGQAEFGPFPFVIVP 281


>gi|153791494 Rhox homeobox family, member 2B [Homo sapiens]
          Length = 288

 Score =  115 bits (289), Expect = 5e-26
 Identities = 87/258 (33%), Positives = 122/258 (47%), Gaps = 32/258 (12%)

Query: 21  EDIEEVNDEKLTVTSLMARGGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQD-----RE 75
           +D +E+ D    V SL     E+EE+ + +PE GT A   + + G+   +++D     ++
Sbjct: 20  DDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKD 79

Query: 76  GGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135
           GGG   P    E       E        +E   + E+ P      PQ A G     G +P
Sbjct: 80  GGGAGVPGHLWEG----NLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVG-----GLEP 130

Query: 136 PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWK 195
              ++    AFT  QLQELE  F   Q+P    R RLA  +N+TE  VQ+WF+NRRAKW+
Sbjct: 131 GNAQQPNVHAFTPLQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWR 190

Query: 196 RNQRVLMLRN-----------TATADLAHPLDMFLGGA---YYAAPALDPALCVHLVPQL 241
           R+QR LM RN             TA  A    +F+ G    Y+   +   +LC  + P  
Sbjct: 191 RHQRALMARNMLPFMAVGQPVMVTAAEAITAPLFISGMRDDYFWDHSHSSSLCFPM-PPF 249

Query: 242 PRPPVLPVPPM--PPRPP 257
           P PP LP+P M  PP PP
Sbjct: 250 P-PPSLPLPLMLLPPMPP 266



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 6/41 (14%)

Query: 302 PVPPWPPMAPVPTGP-PMAPVPPGPPMARVPPGP-PMARVP 340
           P+PP+PP    P+ P P+  +PP PP  +   GP P   VP
Sbjct: 245 PMPPFPP----PSLPLPLMLLPPMPPAGQAEFGPFPFVIVP 281


>gi|23943886 Rhox homeobox family, member 1 [Homo sapiens]
          Length = 184

 Score =  109 bits (273), Expect = 4e-24
 Identities = 66/160 (41%), Positives = 84/160 (52%), Gaps = 35/160 (21%)

Query: 51  PEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ 110
           PE G   EN +  +G +  +     GGG  EP QQ + PP                    
Sbjct: 50  PEGGVNHENGMNRDGGMIPEG----GGGNQEPRQQPQPPP-------------------- 85

Query: 111 EEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARE 170
           EEP Q  +EGPQP       E  QP    R RRT FT  Q++ELE+ F  +QYPDV  R 
Sbjct: 86  EEPAQAAMEGPQP-------ENMQP----RTRRTKFTLLQVEELESVFRHTQYPDVPTRR 134

Query: 171 RLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATAD 210
            LA  L +TED+V+VWF+N+RA+ +R+QR LML N   AD
Sbjct: 135 ELAENLGVTEDKVRVWFKNKRARCRRHQRELMLANELRAD 174


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score =  104 bits (259), Expect = 2e-22
 Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 31/197 (15%)

Query: 232 ALCVHLVPQLP-RPPVLPVPPMP-------PRPPM-----VPMPPRPPIAPMPPMA---- 274
           A  + + P +P R PV P PP+P       P PP       P PP PP  P PP+     
Sbjct: 558 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 617

Query: 275 -----PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMAR 329
                 +P G+ ++P PP    A +PP PP+      P  + +P G  + P PP P  AR
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 677

Query: 330 VPPGPP----MARVPPGPPMAP----LPPGPPMAPLPPG-PPMAPLPPGPPMAPLPPRSH 380
           +PP PP     A +PP PP  P    +PP PP  P  PG PP  P P GP + P PP   
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 737

Query: 381 VPHTGLAPVHITWAPVI 397
           +P        +  APV+
Sbjct: 738 MPPPPPFGFGVPAAPVL 754



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 58/152 (38%), Positives = 74/152 (48%), Gaps = 16/152 (10%)

Query: 227 PALDPALCVHLVPQLPRPPVL-PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285
           P L   +C+   P LP    + P PP+     + P PP P    +P  + +P G+ + P 
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 669

Query: 286 PPGPRMAPVPPWPPMAP----VPPWPPMAPVPTG--PPMAPVPPGPPMARVPPGPPMARV 339
           PP P  A +PP PP  P    +PP PP  P   G  PP  P+P GP    +PP PP    
Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG---IPPPPPF--- 723

Query: 340 PPGPPMAPLPPGPPMAPLPP---GPPMAPLPP 368
           P GP + P PPG  M P PP   G P AP+ P
Sbjct: 724 PGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score =  104 bits (259), Expect = 2e-22
 Identities = 70/197 (35%), Positives = 91/197 (46%), Gaps = 31/197 (15%)

Query: 232 ALCVHLVPQLP-RPPVLPVPPMP-------PRPPM-----VPMPPRPPIAPMPPMA---- 274
           A  + + P +P R PV P PP+P       P PP       P PP PP  P PP+     
Sbjct: 567 AAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVC 626

Query: 275 -----PVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMAR 329
                 +P G+ ++P PP    A +PP PP+      P  + +P G  + P PP P  AR
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSAR 686

Query: 330 VPPGPP----MARVPPGPPMAP----LPPGPPMAPLPPG-PPMAPLPPGPPMAPLPPRSH 380
           +PP PP     A +PP PP  P    +PP PP  P  PG PP  P P GP + P PP   
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMG 746

Query: 381 VPHTGLAPVHITWAPVI 397
           +P        +  APV+
Sbjct: 747 MPPPPPFGFGVPAAPVL 763



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 58/152 (38%), Positives = 74/152 (48%), Gaps = 16/152 (10%)

Query: 227 PALDPALCVHLVPQLPRPPVL-PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285
           P L   +C+   P LP    + P PP+     + P PP P    +P  + +P G+ + P 
Sbjct: 619 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPP 678

Query: 286 PPGPRMAPVPPWPPMAP----VPPWPPMAPVPTG--PPMAPVPPGPPMARVPPGPPMARV 339
           PP P  A +PP PP  P    +PP PP  P   G  PP  P+P GP    +PP PP    
Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG---IPPPPPF--- 732

Query: 340 PPGPPMAPLPPGPPMAPLPP---GPPMAPLPP 368
           P GP + P PPG  M P PP   G P AP+ P
Sbjct: 733 PGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764


>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
           sapiens]
          Length = 184

 Score =  103 bits (258), Expect = 2e-22
 Identities = 66/153 (43%), Positives = 80/153 (52%), Gaps = 34/153 (22%)

Query: 123 PAEGPQTAEG------PQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARL 176
           P EGP T  G        P ++ RR RT FT +QL +LE  F+ S YPDV +RE LAA++
Sbjct: 5   PGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKV 64

Query: 177 NLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVH 236
           +L E RVQVWFQNRRAKW+R +R                 +  G    AAP L  A    
Sbjct: 65  HLPEVRVQVWFQNRRAKWRRQER-----------------LESGSGAVAAPRLPEA---- 103

Query: 237 LVPQLP--RPPVLPVPPMP---PRPPMVPMPPR 264
             P LP  RPP + +P  P   P PP VP  PR
Sbjct: 104 --PALPFARPPAMSLPLEPWLGPGPPAVPGLPR 134



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 9/59 (15%)

Query: 329 RVPPGP--PMARVPPGPPMAPLPPGPPMAPLPPGPPMAP--LPPGPPM-APLPPRSHVP 382
           R+P  P  P AR    PP   LP  P + P PP  P  P  L PGP + A   P +  P
Sbjct: 99  RLPEAPALPFAR----PPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAP 153


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 75/223 (33%), Positives = 103/223 (46%), Gaps = 27/223 (12%)

Query: 74  REGGGGHEPEQQ----QEEPPLTKPEQQQEEPPL------LELKQEQEEPPQTTVEGPQP 123
           +EG  GH    Q     +E  L +PE   +   +      L +K+   + PQ       P
Sbjct: 140 QEGSSGHSAALQVPCYAKESSLGEPELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLP 199

Query: 124 AEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRV 183
           +   + A+      +KRR RT FT +QL+ELE  F ++ YPDV ARE+LA R +LTE RV
Sbjct: 200 SP-LEKADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARV 258

Query: 184 QVWFQNRRAKWKRNQRVLMLRNTAT-ADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP 242
           QVWFQNRRAKW++ +R   ++   T    A+ L +      YA              Q+ 
Sbjct: 259 QVWFQNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYA--------------QIQ 304

Query: 243 RPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV 285
            P  L         P   +P  P  A M P A  PPGS  + V
Sbjct: 305 NPSWLGNNGAASPVPACVVPCDPVPACMSPHAH-PPGSGASSV 346


>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 98.6 bits (244), Expect = 9e-21
 Identities = 59/142 (41%), Positives = 74/142 (52%), Gaps = 14/142 (9%)

Query: 120 GPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLT 179
           GPQ    P  A   Q  ++++R RT FT  QL ELE  F ++ YPD+  RE LA R+ LT
Sbjct: 85  GPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144

Query: 180 EDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHP-LDMFLGGAYYAAPALDPALC---- 234
           E RVQVWFQNRRAKWK+ ++   +       L  P L  F   A  AA A+  +LC    
Sbjct: 145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHA 204

Query: 235 ---------VHLVPQLPRPPVL 247
                    +  V QLP PP L
Sbjct: 205 NDTRWAAAAMPGVSQLPLPPAL 226


>gi|14149760 orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 98.6 bits (244), Expect = 9e-21
 Identities = 59/142 (41%), Positives = 74/142 (52%), Gaps = 14/142 (9%)

Query: 120 GPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLT 179
           GPQ    P  A   Q  ++++R RT FT  QL ELE  F ++ YPD+  RE LA R+ LT
Sbjct: 85  GPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144

Query: 180 EDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHP-LDMFLGGAYYAAPALDPALC---- 234
           E RVQVWFQNRRAKWK+ ++   +       L  P L  F   A  AA A+  +LC    
Sbjct: 145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSLCSFHA 204

Query: 235 ---------VHLVPQLPRPPVL 247
                    +  V QLP PP L
Sbjct: 205 NDTRWAAAAMPGVSQLPLPPAL 226


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 62/143 (43%), Positives = 69/143 (48%), Gaps = 17/143 (11%)

Query: 244 PPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPV 303
           PP  P    PPRPP+ P  P  P  P PP   +PP     P+   P     PP P + P 
Sbjct: 227 PPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPP-----PLAGPPNRGDRPPPPVLFPG 281

Query: 304 PPW--PPMAPVPTGPPMAPVPP-GPPMARVPP--GPPMARVPPGPPMAPLPPGPPMAPLP 358
            P+  PP+ P+P GPP  PVP  GPP    PP  GPP    PP  P  P PPGP   PL 
Sbjct: 282 QPFGQPPLGPLPPGPP-PPVPGYGPPPGPPPPQQGPP----PPPGPFPPRPPGPLGPPLT 336

Query: 359 PGPPMAPLPPGPPMAPLPPRSHV 381
             PP  P  PGPP    PP  HV
Sbjct: 337 LAPP--PHLPGPPPGAPPPAPHV 357



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 60/162 (37%), Positives = 70/162 (43%), Gaps = 35/162 (21%)

Query: 242 PRPPVLPV-PPMPPRPP----MVPMP----------PRPPIA------PMPPMAPVPPGS 280
           PRPP+ P  PP PP PP    ++P P          P PP+         PP+ P+PPG 
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG- 295

Query: 281 RMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVP----PGPPM 336
              P PP P   P PP PP     P PP  P    PP  P P GPP+   P    PGPP 
Sbjct: 296 ---PPPPVPGYGP-PPGPPPPQQGPPPPPGPF---PPRPPGPLGPPLTLAPPPHLPGPPP 348

Query: 337 ARVPPGPPMAP-LPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377
              PP P + P   P P  + +P      P PP  P    PP
Sbjct: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGP-PPTDPYGRPPP 389



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 64/156 (41%), Positives = 69/156 (44%), Gaps = 32/156 (20%)

Query: 238 VPQLPRPPVLPVPPMPPRP-PMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
           VP   R P    P  PP P P    PPRPP+ P     P PPG      PPGP       
Sbjct: 211 VPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGP-----PGPPG------PPGP------- 252

Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVP---PGPPMARVPPGPPMARVPPGPPMAPLPP-GP 352
            PP   V P PP+A  P      P P   PG P  + P GP    +PPGPP  P+P  GP
Sbjct: 253 -PPPGQVLP-PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGP----LPPGPP-PPVPGYGP 305

Query: 353 PMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAP 388
           P  P PP P   P PP  P  P PP    P   LAP
Sbjct: 306 P--PGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 43/110 (39%), Positives = 47/110 (42%), Gaps = 9/110 (8%)

Query: 238 VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW 297
           VP    PP  P P   P PP  P PPRPP    PP+   PP     P  PGP     PP 
Sbjct: 300 VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP-----PHLPGPPPGAPPPA 354

Query: 298 PPMAPV--PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPM 345
           P + P   PP P  + +PT     P PP  P  R PP       PPG  M
Sbjct: 355 PHVNPAFFPP-PTNSGMPTSDSRGP-PPTDPYGRPPPYDRGDYGPPGREM 402



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 32/85 (37%), Positives = 34/85 (40%), Gaps = 9/85 (10%)

Query: 313 PTGPPMAPVPPGPP-MARVPPGPPMARVPPGPPMA-----PLPPG--PPMAPL-PPGPPM 363
           P G   A  P G     R P   P     PGP        P P G  PP  PL PPGPP 
Sbjct: 189 PGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPG 248

Query: 364 APLPPGPPMAPLPPRSHVPHTGLAP 388
            P PP P     PP +  P+ G  P
Sbjct: 249 PPGPPPPGQVLPPPLAGPPNRGDRP 273



 Score = 28.9 bits (63), Expect = 8.7
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 4/67 (5%)

Query: 76  GGGGHEPEQQQEEPPLTKPEQQQEE--PPLLELKQEQEEPPQTTVE--GPQPAEGPQTAE 131
           G  G  P  Q   PPL  P  + +   PP+L   Q   +PP   +    P P  G     
Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPP 307

Query: 132 GPQPPER 138
           GP PP++
Sbjct: 308 GPPPPQQ 314


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 61/142 (42%), Positives = 68/142 (47%), Gaps = 10/142 (7%)

Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP 298
           PQ   P  +  PPMP  PP+ P PP PP+ P  P   +PPG    P P  P     P  P
Sbjct: 394 PQSVPPSQIQAPPMPGPPPLGP-PPAPPLRPPGPPTGLPPG----PPPGAPPFLRPPGMP 448

Query: 299 PM-APVPPWPPMAPVPTGPPMAP--VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMA 355
            +  P+P   P  P P  PP  P   PPG P    P GPP    PP PP  P PP P M 
Sbjct: 449 GLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIP-PPRPGMM 507

Query: 356 PLPPGPPMAPLPPGP-PMAPLP 376
             P  PP+ P PPG  P APLP
Sbjct: 508 RPPLVPPLGPAPPGLFPPAPLP 529



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 58/126 (46%), Positives = 61/126 (48%), Gaps = 14/126 (11%)

Query: 272 PMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPV---PPGPPMA 328
           P   VPP    AP  PGP     PP PP+ P  P PP    P  PP AP    PPG P  
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLRP--PGPPTGLPPGPPPGAPPFLRPPGMPGL 450

Query: 329 R------VPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVP 382
           R      +PPGPP  R PPGPP  P PPG P  P P GPP    PP PP  P PPR  + 
Sbjct: 451 RGPLPRLLPPGPPPGR-PPGPPPGP-PPGLPPGPPPRGPPPRLPPPAPPGIP-PPRPGMM 507

Query: 383 HTGLAP 388
              L P
Sbjct: 508 RPPLVP 513



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 63/139 (45%), Positives = 68/139 (48%), Gaps = 18/139 (12%)

Query: 239 PQLPRPPVLPVPPMPP-RPPMVP--MPPRPPIAPMPPMAPVP-PGSR------MAPVPPG 288
           P +P PP L  PP PP RPP  P  +PP PP    P + P   PG R      + P PP 
Sbjct: 405 PPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPP 464

Query: 289 PRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPL 348
            R    PP PP    P  PP  P P  PP  P PPG P    PP P M R P  PP+ P 
Sbjct: 465 GRPPGPPPGPPPGLPPGPPPRGPPPRLPP--PAPPGIP----PPRPGMMRPPLVPPLGPA 518

Query: 349 PPGP-PMAPLP-PGPPMAP 365
           PPG  P APLP PG   AP
Sbjct: 519 PPGLFPPAPLPNPGVLSAP 537



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 37/90 (41%), Positives = 44/90 (48%), Gaps = 12/90 (13%)

Query: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPV------PPGPRMAPVP 295
           P P +LP  P P RPP  P  P P + P PP    PP  R+ P       PP P M   P
Sbjct: 453 PLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPP--RLPPPAPPGIPPPRPGMMRPP 510

Query: 296 PWPPMAPVPP--WPPMAPVPTGPPMAPVPP 323
             PP+ P PP  +PP AP+P  P +   PP
Sbjct: 511 LVPPLGPAPPGLFPP-APLP-NPGVLSAPP 538



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/72 (38%), Positives = 32/72 (44%), Gaps = 7/72 (9%)

Query: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAP-MPPMAPVPPGSRMAPV 285
           P   P L     P+ P PP LP P  P  PP  P   RPP+ P +    P PPG    P 
Sbjct: 472 PGPPPGLPPGPPPRGP-PPRLPPPAPPGIPPPRPGMMRPPLVPPL---GPAPPG-LFPPA 526

Query: 286 P-PGPRMAPVPP 296
           P P P +   PP
Sbjct: 527 PLPNPGVLSAPP 538



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 25/83 (30%), Positives = 30/83 (36%), Gaps = 14/83 (16%)

Query: 269 PMPPMAPVPPGSRMAPVP-PGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPM 327
           P+P M   P    +  +P PG +             PP         GPP   V   P +
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQ-------------PPSILKKTSAYGPPTRAVSILPLL 186

Query: 328 ARVPPGPPMARVPPGPPMAPLPP 350
               P  P  R PPGPP  P PP
Sbjct: 187 GHGVPRLPPGRKPPGPPPGPPPP 209



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 7/93 (7%)

Query: 51  PEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ 110
           PE G E E     +    SDD + E     + +++      +    QQ+ PP      + 
Sbjct: 343 PEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQI 402

Query: 111 EEPPQTTVE--GPQPA-----EGPQTAEGPQPP 136
           + PP       GP PA      GP T   P PP
Sbjct: 403 QAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPP 435



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 20/71 (28%), Positives = 26/71 (36%)

Query: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLP 367
           P+  +P  P    +   P     PP         GPP   +   P +    P  P    P
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199

Query: 368 PGPPMAPLPPR 378
           PGPP  P PP+
Sbjct: 200 PGPPPGPPPPQ 210



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 21/70 (30%), Positives = 25/70 (35%)

Query: 299 PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLP 358
           P+  +P  P    +   P     PP         GPP   V   P +    P  P    P
Sbjct: 140 PLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP 199

Query: 359 PGPPMAPLPP 368
           PGPP  P PP
Sbjct: 200 PGPPPGPPPP 209



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 22/77 (28%), Positives = 27/77 (35%), Gaps = 6/77 (7%)

Query: 247 LPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPW 306
           +P+P MP  P  +       I  +P     PP         GP    V   P +    P 
Sbjct: 139 IPLPDMPHAPSNIL------IQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPR 192

Query: 307 PPMAPVPTGPPMAPVPP 323
            P    P GPP  P PP
Sbjct: 193 LPPGRKPPGPPPGPPPP 209



 Score = 29.3 bits (64), Expect = 6.7
 Identities = 40/163 (24%), Positives = 64/163 (39%), Gaps = 40/163 (24%)

Query: 123 PAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDR 182
           P + PQ  E     +RK+ R T     +L E EN       PD+    R          +
Sbjct: 67  PVQQPQLNEKVLKDKRKKLRETFERILRLYEKEN-------PDIYKELR----------K 109

Query: 183 VQVWFQNRRAKWK------RNQRVLMLRNTATADLAHP------LDMFLGGAYYAAPAL- 229
           ++V ++ +RA+        +N + + + +    D+ H        D+ L GA    P++ 
Sbjct: 110 LEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQ--PPSIL 167

Query: 230 -------DPALCVHLVPQLPRP-PVLPVPPMPPRPPMVPMPPR 264
                   P   V ++P L    P LP    PP PP  P PP+
Sbjct: 168 KKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQ 210


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 89/287 (31%), Positives = 112/287 (39%), Gaps = 78/287 (27%)

Query: 55  TEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQ---- 110
           T  E  +G  G  P       GG G E +   EE  L   E + EE  LLE  +E+    
Sbjct: 199 THPEERLGVAGG-PGSAPAAGGGTGTEDD---EEELLEDEEDEDEEEELLEDDEEELLED 254

Query: 111 ------EEPPQTTV----------------EGPQ--PAEG----PQTAEGPQPPE----- 137
                 +EP +  V                EG +  P E     P+ AEG    +     
Sbjct: 255 DARALLKEPRRCPVAATGAVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLS 314

Query: 138 ------------RKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQV 185
                       ++RR RT FT +QL+ELE  F ++ YPDV  RE LA RL+LTE RVQV
Sbjct: 315 AGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQV 374

Query: 186 WFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPP 245
           WFQNRRAKW++ ++             HP  +         P   P    H     P  P
Sbjct: 375 WFQNRRAKWRKREK--------AGAQTHPPGL---------PFPGPLSATH-----PLSP 412

Query: 246 VLPVPPMPPRPPMVP---MPPRPPIAPMPPMAPVPPGSRMAPVPPGP 289
            L   P PP  P +           A   P  P PPGS   P    P
Sbjct: 413 YLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAP 459



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 13/65 (20%)

Query: 322 PPGPPMARVPPGPPMARVPPGPPM--APLPPGPPM-------APLPPGPPMAPLPPGPPM 372
           PPG P     PGP  A  P  P +  +P PP  P        A          LPP P  
Sbjct: 395 PPGLPF----PGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGS 450

Query: 373 APLPP 377
           A LPP
Sbjct: 451 ASLPP 455


>gi|4557489 cone-rod homeobox protein [Homo sapiens]
          Length = 299

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 84/262 (32%), Positives = 112/262 (42%), Gaps = 40/262 (15%)

Query: 118 VEGPQPAEGPQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLN 177
           + GP      Q    P  P ++RR RT FT+ QL+ELE  F ++QYPDV ARE +A ++N
Sbjct: 18  LSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKIN 77

Query: 178 LTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHL 237
           L E RVQVWF+NRRAK ++ ++    +               GG   A PA   A     
Sbjct: 78  LPESRVQVWFKNRRAKCRQQRQQQKQQQQPP-----------GGQAKARPAKRKA----- 121

Query: 238 VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW 297
               PRP       + P P  +     PP+       P P GS      P   +A V  W
Sbjct: 122 -GTSPRPST----DVCPDPLGISDSYSPPL-------PGPSGS------PTTAVATVSIW 163

Query: 298 PPM--APVPPWPPMAPVPTGPPMAPVPPGPPMARVPP--GPPMARVPPGPPMAPLPPG-P 352
            P   +P+P       V +GP +   P     A        P A   P    + L P   
Sbjct: 164 SPASESPLPEAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLDPYLS 223

Query: 353 PMAPLPPGPPMAPLPPGPPMAP 374
           PM P   GP ++PL  GP + P
Sbjct: 224 PMVPQLGGPALSPL-SGPSVGP 244


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 63/174 (36%), Positives = 82/174 (47%), Gaps = 30/174 (17%)

Query: 121 PQPAEGPQTAEGPQPPERK--RRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNL 178
           PQ  E P    G     +K  RR RT F   QLQ LE  F+ + YPD   RE LA R+NL
Sbjct: 84  PQDGECPSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNL 143

Query: 179 TEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVHLV 238
           +E RVQVWFQNRRAK++RN+R ++   +A+          L  +Y    A++        
Sbjct: 144 SEARVQVWFQNRRAKFRRNERAMLASRSAS----------LLKSYSQEAAIEQ------- 186

Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292
           P  PRP  L        P  +      P + +PP +P   G    P  PG  MA
Sbjct: 187 PVAPRPTAL-------SPDYLSWTASSPYSTVPPYSPGSSG----PATPGVNMA 229


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 60/174 (34%), Positives = 80/174 (45%), Gaps = 16/174 (9%)

Query: 227 PALDPALCVHLVPQLPRPPVLPVPPMPPR-PPMVPMPP--RPPIAPM-PPMAPVPPGSRM 282
           P   PAL    +  LP PP+ P+   PP+ PP + +PP   PP  P  PP++P+   S  
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651

Query: 283 APVPPGPRMAPVPPWPPMAPV-------PPWPPMAPVPTGPPMAPVPPGPPMARVPPGPP 335
           AP      +   P  PP +P        P  PP++P  T P  AP     P  +VPP PP
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711

Query: 336 MARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPV 389
            +     PPM+P    PP AP P   P   +PP PP +P    S  P   + P+
Sbjct: 712 AS-----PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 59/166 (35%), Positives = 70/166 (42%), Gaps = 22/166 (13%)

Query: 226 APALDPALCVHLVPQLPRPPVLPVPPM--PPRPPMVPMPPRPPIAPMPPMAPVPPGSRMA 283
           +P   P +     P    PP L  PP+  PP PP    PP  P A  PP AP P  +   
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAPPPLAAPPL 735

Query: 284 PVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGP 343
            VPP P              P  PPM+P  T PP  P     P  +VPP PP A +P  P
Sbjct: 736 QVPPSP--------------PASPPMSPSATPPPRVPPLLAAPPLQVPPSPP-ASLPMSP 780

Query: 344 PMAPLPPGPPMAPLPPGPPMAPLPPG--PPMAPLPPRSHVPHTGLA 387
              P P  PP    PP   + P PP   P  AP  P + +P + LA
Sbjct: 781 LAKPPPQAPPALATPPLQAL-PSPPASFPGQAPFSPSASLPMSPLA 825



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 68/190 (35%), Positives = 86/190 (45%), Gaps = 35/190 (18%)

Query: 225 AAPALDPALCVHLVPQLPRP---PVLPVPPMPPR----------PPMVP---------MP 262
           A+P + P+      PQ P P   P L VPP PP           PP VP         +P
Sbjct: 712 ASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP 769

Query: 263 PRPPIA-PMPPMAPVPPGSRMAPVPPGPRMAPVPP--WPPMAPVPPWP--PMAPVPTGPP 317
           P PP + PM P+A  PP +  A   P  +  P PP  +P  AP  P    PM+P+ T PP
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 318 MAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377
            AP     P+ +VPP PP +     P   P  PGP  +   P   +A L PGPP    PP
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPP-TPGPDTSVSGPRLTLA-LAPGPP----PP 883

Query: 378 RSHVPHTGLA 387
            S  P + L+
Sbjct: 884 PSRSPSSTLS 893



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 67/186 (36%), Positives = 81/186 (43%), Gaps = 37/186 (19%)

Query: 239 PQLPRPPVLPVPPMPPR-PPMVPMPPRPPIAPMPPMAP---VPPGSRMAP-----VPPGP 289
           P L  PP L VPP PP  PPM P    PP AP P  AP   VPP    +P       P P
Sbjct: 697 PSLAAPP-LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755

Query: 290 RMAP--------VPPWPPM-APVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMA--- 337
           R+ P        VPP PP         PM+P+   PP AP     P  +  P PP +   
Sbjct: 756 RVPPLLAAPPLQVPPSPPASL------PMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809

Query: 338 RVPPGP----PMAPLPPGPPMAPLPPGPPMAPLPPGPP-----MAPLPPRSHVPHTGLAP 388
           + P  P    PM+PL   PP AP     P+  +PP PP      AP  P +  P T ++ 
Sbjct: 810 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 869

Query: 389 VHITWA 394
             +T A
Sbjct: 870 PRLTLA 875



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 59/194 (30%), Positives = 73/194 (37%), Gaps = 25/194 (12%)

Query: 225 AAPALDPALCVHLVPQLPRPPVLPVPPM-----PPRPPMVPMPPRPPIAPMPPMAPVPPG 279
           A P+L         P L   P L  PP+     P   P +  PP P  AP P  AP  P 
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP--APCPLQAPPSPL 576

Query: 280 SRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARV 339
           +   P  P     P P  PP    PP   +   P  P   P P  PP   +PP       
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636

Query: 340 PPGPPMAPLPPGPPMAP-------------LPPGPPM-APL--PPGPPMAP--LPPRSHV 381
           P  PP++PL    P AP              PP PP+ AP   P  PP++P   PP    
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 696

Query: 382 PHTGLAPVHITWAP 395
           P     P+ +  +P
Sbjct: 697 PSLAAPPLQVPPSP 710



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 60/191 (31%), Positives = 75/191 (39%), Gaps = 25/191 (13%)

Query: 204 RNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPP-----RPPM 258
           R +A   L  P    L  +  A P   PA         PR P  P  P P      RPP 
Sbjct: 227 RPSAGGGLQRPASRSLSSS--ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284

Query: 259 VPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPM 318
           V  PPR   AP   + P+       P P G +  PVPP        P     P+P     
Sbjct: 285 VT-PPRKDAAPA--LGPLSSSPLATPSPSGTKARPVPP--------PDNAATPLP----- 328

Query: 319 APVPPGPPMAR-VPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377
           A +PP PP+A  +P  PP    PP     P PP  P +  PP     P+   P +  +PP
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388

Query: 378 RSHVPHTGLAP 388
              VPH+  +P
Sbjct: 389 -IQVPHSLTSP 398



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 56/171 (32%), Positives = 77/171 (45%), Gaps = 24/171 (14%)

Query: 239 PQLPRPPVLPVPPMPPR----PPMVPMPPR----PPIAPMPPMAPVPPGSRMAPV----- 285
           PQ P   ++ +PP+  +    PP +  PP     PP+  +P +AP P  +  AP+     
Sbjct: 500 PQAPLSSLI-MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558

Query: 286 --PPGPRMAPVPPWPPMAPVPPWPPMAP--VPTGPPMAPVP-PGPPMARVPPGP--PMAR 338
             PP P  AP P   P +P+   PP  P  + T PP AP     PP+  +P  P  P+A 
Sbjct: 559 ETPPCP--APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT 616

Query: 339 VPP-GPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAP 388
            PP  PP   LPP       P  PP++PL    P AP     H+     +P
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667



 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 60/162 (37%), Positives = 71/162 (43%), Gaps = 19/162 (11%)

Query: 225 AAPALDP-ALCVHLVPQLPRPPVLPVPPMPPRP-PMVPMPPRPPIAP----MPPMA--PV 276
           A+P + P A     VP L   P L VPP PP   PM P+   PP AP     PP+   P 
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802

Query: 277 PPGSRMAPVPPGPR----MAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPP 332
           PP S     P  P     M+P+   PP AP     P+  VP  PP +P    P   R PP
Sbjct: 803 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPP 859

Query: 333 GPPMARVPPGPPMA-PLPPGPPMAPLPPGPPMAPLPPGPPMA 373
            P       GP +   L PGPP  P P   P + L  GP +A
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPP--PPPSRSPSSTL-SGPDLA 898



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 45/132 (34%), Positives = 53/132 (40%), Gaps = 6/132 (4%)

Query: 266 PIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGP 325
           P AP  P  P P G + A  PP          P + P+   P   P P+G    PVPP  
Sbjct: 263 PRAPAHPSQPKPKGLQ-ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321

Query: 326 PMARVPPGPPMARVPPGPPMA-PLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHT 384
             A   P    A +PP PP+A PLP  PP    PP     P PP  P +  PP    P  
Sbjct: 322 NAATPLP----ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM 377

Query: 385 GLAPVHITWAPV 396
              P   T  P+
Sbjct: 378 QAPPSLQTIPPI 389



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 47/171 (27%), Positives = 67/171 (39%), Gaps = 23/171 (13%)

Query: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPM--PPMAPVPPGSRMAPVPPGPRMAPVPPWPP 299
           P  P    P  PP    + +P  PP+     P ++P+     + P+     +A   P  P
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAP 503

Query: 300 MAPV--PPW-------PPMAPVP----TGPPMAPVPP--GPPM--ARVPPGPPMARVPPG 342
           ++ +  PP        PP    P    T PP+  +P    PP+  A  P   P    PP 
Sbjct: 504 LSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPC 563

Query: 343 PPMAPLPPGP-PMAPLPPGPPMA---PLPPGPPMAPLPPRSHVPHTGLAPV 389
           P   PL   P P+   PP  P +   P P  PP    PP   +P   L+P+
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 34/180 (18%)

Query: 225 AAPALDPALCVHLVPQLPRP----PVLP-----------VPPMPPRPPMVPM-PPRPPIA 268
           AAPAL P     L    P      PV P           +PP PP    +P+ PP P   
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP 351

Query: 269 PMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGP--- 325
           P     P PP +  +  PP     P+   P +  +P  P   P     P    PP P   
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--PIQVPHSLTSPSLQAPPSPLAL 409

Query: 326 --PMARVPPGPPMAR-------VPPGPPMAPL-PPGPPMAPLPPGPPM-AP--LPPGPPM 372
               A    G P  +       + P    A L  P  P +  P  PP+ AP  LP  PP+
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL 469



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 54/222 (24%), Positives = 74/222 (33%), Gaps = 50/222 (22%)

Query: 226 APALDPALCVHLVPQLPRPPVLP---VPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRM 282
           +P+  P+L       LP PP  P    PP    PPM   P    I P+     +   S  
Sbjct: 347 SPSAPPSL-----QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQ 401

Query: 283 APVPP-------------GPRMAPVPPWPPMAP-------VPPWPPMAPVPTGPPM-AP- 320
           AP  P              P +     +  M+P         P  P +  P  PP+ AP 
Sbjct: 402 APPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461

Query: 321 -VPPGPPM-----ARVPPGPPMARVPPGPPMAPLPPGPPMAPL-----PP-------GPP 362
            +P  PP+       V P      + P   ++ L    P APL     PP        PP
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521

Query: 363 MAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAPVINSYYACP 404
               PP       PP  ++P     P+    AP+   +   P
Sbjct: 522 SLQTPPA--SLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 30/105 (28%), Positives = 36/105 (34%), Gaps = 6/105 (5%)

Query: 242 PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVP-PGPRMAPVPPWPPM 300
           PRPP  P PP P  P  + +          P+A    G   A +P   PR  P       
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86

Query: 301 APVPPWPPMAP--VPTGPPMAPVPPGPPMARVPPGPPMARVPPGP 343
           +  P   P A       PP     PGP  +   PG       PGP
Sbjct: 87  SRNPASRPPASGRGERAPPAKNTSPGPVSS---PGRASGTTRPGP 128



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 27/104 (25%), Positives = 33/104 (31%), Gaps = 3/104 (2%)

Query: 261 MPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320
           + PRPP +P PP    P   R+          P+            P  AP       A 
Sbjct: 25  LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84

Query: 321 VPPGPPMARVPPGPPMARVPPGPPMAPLP---PGPPMAPLPPGP 361
                P +R P      R PP    +P P   PG       PGP
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128


>gi|169881277 PROP paired-like homeobox 1 [Homo sapiens]
          Length = 226

 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 72/212 (33%), Positives = 99/212 (46%), Gaps = 40/212 (18%)

Query: 93  KPEQQQEEPPLLELKQEQEEPPQTTVEGPQP-------AEGPQTAEGPQP-----PERKR 140
           KP++ +    LL  +      P TTV+   P       A G ++   PQ      P  +R
Sbjct: 11  KPKKGRVGSNLLPERHPATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRR 70

Query: 141 RRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRV 200
           R RT F+  QL++LE+ F  +QYPD+ ARE LA    L+E R+QVWFQNRRAK ++ +R 
Sbjct: 71  RHRTTFSPVQLEQLESAFGRNQYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERS 130

Query: 201 LM--LRNTATADLAHPLDMFLGGAY-YAAPALDPALCV-----HLVPQLPR--------- 243
           L+  L + + A  +  L       Y YAAP   P  C      H +P  P          
Sbjct: 131 LLQPLAHLSPAAFSSFLPESTACPYSYAAPP-PPVTCFPHPYSHALPSQPSTGGAFALSH 189

Query: 244 ------PPVLPVP----PMPPRPPMVPMPPRP 265
                 P + P P    P PP PPM+P+   P
Sbjct: 190 QSEDWYPTLHPAPAGHLPCPPPPPMLPLSLEP 221


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 58/137 (42%), Positives = 75/137 (54%), Gaps = 7/137 (5%)

Query: 127 PQTAEGPQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVW 186
           P + E  +   +KRR RT F+ FQL+ELE  F ++ YPDV ARE+LA R +LTE RVQVW
Sbjct: 141 PDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVW 200

Query: 187 FQNRRAKWKRNQRVLML---RNTATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPR 243
           FQNRRAKW++ +R   +   RN  TA      D+ +     + P L  +L        P 
Sbjct: 201 FQNRRAKWRKRERYGKIQEGRNPFTA----AYDISVLPRTDSHPQLQNSLWASPGSGSPG 256

Query: 244 PPVLPVPPMPPRPPMVP 260
            P L  P   P P M P
Sbjct: 257 GPCLVSPEGIPSPCMSP 273



 Score = 36.6 bits (83), Expect = 0.042
 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 13/84 (15%)

Query: 290 RMAPVP-PWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPL 348
           R+ P P P+      PP P   P    P + P PP         GP + R P   P+ P 
Sbjct: 10  RVGPAPGPYVASGDEPPGPQGTPA-AAPHLHPAPPR--------GPRLTRFPACGPLEPY 60

Query: 349 PPGPPMAPLPPGPPMAPLPPGPPM 372
            P P     PP   +  L PGP +
Sbjct: 61  LPEPAK---PPAKYLQDLGPGPAL 81



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 28/78 (35%), Positives = 31/78 (39%), Gaps = 13/78 (16%)

Query: 319 APVPPGPPMARVPPGPPMAR--VPPGPPMAP-----LPPGPPMAP-LPPGPPMAPLPPGP 370
           AP   GP      PGP +A    PPGP   P     L P PP  P L   P   PL P  
Sbjct: 7   APFRVGPA-----PGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYL 61

Query: 371 PMAPLPPRSHVPHTGLAP 388
           P    PP  ++   G  P
Sbjct: 62  PEPAKPPAKYLQDLGPGP 79



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 40/136 (29%), Positives = 47/136 (34%), Gaps = 24/136 (17%)

Query: 253 PPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPP-GPRMAPVPPWPPMAPVPPWPPMAP 311
           P   P V     PP  P    A  P    + P PP GPR+   P   P+ P  P P   P
Sbjct: 13  PAPGPYVASGDEPP-GPQGTPAAAP---HLHPAPPRGPRLTRFPACGPLEPYLPEPAKPP 68

Query: 312 VPTGPPMAPVPPGPPM--ARVPPGPPMARVPPGP----PMAPLP------PGPPMAPLPP 359
                 +  + PGP +       GP  A          P  PL        GP      P
Sbjct: 69  AKY---LQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSP 125

Query: 360 GPPMA----PLPPGPP 371
           GP +A    PL PG P
Sbjct: 126 GPCLASLHLPLSPGLP 141



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 30/117 (25%), Positives = 42/117 (35%), Gaps = 18/117 (15%)

Query: 244 PPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPP 296
           P + P PP  PR  +   P   P+ P  P    PP   +  + PGP +        P   
Sbjct: 36  PHLHPAPPRGPR--LTRFPACGPLEPYLPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEA 93

Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPP 353
               +    +P +     G P      GP   +  PGP +A +       PL PG P
Sbjct: 94  EEKTSKAASFPQLPLDCRGGPR----DGPSNLQGSPGPCLASL-----HLPLSPGLP 141



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 28/76 (36%), Positives = 31/76 (40%), Gaps = 13/76 (17%)

Query: 310 APVPTGPPMAPVPPGPPMAR--VPPGP---PMA--RVPPGPPMAP-LPPGPPMAPLPPGP 361
           AP   GP      PGP +A    PPGP   P A   + P PP  P L   P   PL P  
Sbjct: 7   APFRVGPA-----PGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYL 61

Query: 362 PMAPLPPGPPMAPLPP 377
           P    PP   +  L P
Sbjct: 62  PEPAKPPAKYLQDLGP 77


>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
          Length = 365

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 49/112 (43%), Positives = 65/112 (58%), Gaps = 2/112 (1%)

Query: 89  PPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRR-RTAFT 147
           P    P      PP L  +Q++ +   T+ E  Q  +       P   +RK+RR RT FT
Sbjct: 114 PEPAAPLAPSRPPPALG-RQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFT 172

Query: 148 QFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQR 199
             QL+ELE  F E+ YPDV ARE LA +  L EDR+QVWFQNRRAKW++ ++
Sbjct: 173 AHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 17/116 (14%)

Query: 274 APVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPG 333
           A VP GS     P G  +  +       P P  P       GP +AP P GP +     G
Sbjct: 16  ALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAVAPCP-GPGL----DG 70

Query: 334 PPMAR--VPPG----------PPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377
             +AR  +P G          PP A   P   +A +P  PP  P P  P     PP
Sbjct: 71  SSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPP 126



 Score = 29.3 bits (64), Expect = 6.7
 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 251 PMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMA--PVPPG-PRMAPVPPWPPMAPVPPWP 307
           P P  P        P +AP P   P   GS +A   +P G   +      PP A   P  
Sbjct: 44  PAPAGPGQGSGCEGPAVAPCP--GPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL 101

Query: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMAR 338
            +A VP  PP  P  P  P+A   P P + R
Sbjct: 102 LLADVPFLPPRGP-EPAAPLAPSRPPPALGR 131


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 55/174 (31%), Positives = 85/174 (48%), Gaps = 15/174 (8%)

Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRM------APVPPGP 289
           P  P P  LP  P P    + P P   P++P P   PM+P P  SR+      +P+ P P
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612

Query: 290 RMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLP 349
             +P+ P P  + + P P  +P+   P  +P+ P P ++R+ P P ++R+ P P  +PL 
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672

Query: 350 PGPPMAPLPPGPPMAPLPPGP---PMAPLP---PRSHVPHTGLAPVHITWAPVI 397
           P P  +P  P P  + L P P   P +P P   P S  P   L  + +  +P++
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 51/155 (32%), Positives = 72/155 (46%), Gaps = 12/155 (7%)

Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVPPGPRMAPVP 295
           P  P P   P+ P P    + P P   P++P P   PM+P P  SR++P+P   R++P P
Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPP 666

Query: 296 PWPPMAPVPPWPPMAPVP----TGPPMAPVPPGPPMARVPPGPP-----MARVPPGPPMA 346
              P++P P   P +P P      PP    P  PP    P  PP     M+      P+ 
Sbjct: 667 EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL 726

Query: 347 PLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHV 381
           PLP  P + P   GP ++P P  P ++P P   H+
Sbjct: 727 PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHL 761



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 55/177 (31%), Positives = 74/177 (41%), Gaps = 27/177 (15%)

Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVPPGPRMAPVP 295
           P  P P   P+ P P    + P     P++P P   P++P P  SR++P P    M+P P
Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPP 639

Query: 296 PWPPMAPVPPWPPMAPVPT----GPPMAPVPPGPPMARVPPGPP--MARVPPGPPMAPLP 349
              PM+P P    ++P+P      PP    P  PP    P  PP   +R+ P P  +P  
Sbjct: 640 EESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699

Query: 350 PGPPMAPLPPGP------------PMAPLPPGPPMAP------LPPRSHVPHTGLAP 388
           P P  +P  P P            P+ PLP  P + P      L PR   PH    P
Sbjct: 700 PPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP 756



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 53/165 (32%), Positives = 71/165 (43%), Gaps = 27/165 (16%)

Query: 239 PQLPRPPVLPVPPMPPRPPMVPM-----------PPRP----PIAPMPPMAPVPPGSRMA 283
           P  P P   P+ P P   P  P+           PP P    P++P P  +P+ P    +
Sbjct: 493 PLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552

Query: 284 PVPPGPRMAPVPPWPP---MAPVPPWPPMAPVPTGPPMAPVPPG----PPMARVPPGPPM 336
           P+ P P   P  P P    ++P P   PM+P P   PM+P P      PP    P  PP 
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP 612

Query: 337 ARVPPGPP-----MAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLP 376
              P  PP     ++P P   PM+P P   PM+P P    ++PLP
Sbjct: 613 EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 74/301 (24%), Positives = 119/301 (39%), Gaps = 23/301 (7%)

Query: 87  EEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRRRTAF 146
           EE PL+ P ++    P  E  +    PP+ +   P P E P +     PPE  R     F
Sbjct: 550 EESPLSPPPEELPTSPPPEASR-LSPPPEESPMSPPPEESPMSP----PPEASR----LF 600

Query: 147 TQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRNT 206
             F+   L    +ES     ++    A+RL+   +   +      +       V  L   
Sbjct: 601 PPFEESPLSPPPEESP----LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656

Query: 207 ATADLAHPL--DMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPR 264
                  P   +  L      +P   P     L P     P  P P   P  P    PP 
Sbjct: 657 PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP----PPE 712

Query: 265 PPIAPMP----PMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAP 320
             +  +P    P+ P+P   ++ P   GP ++P P  P ++P P  P ++P    P ++P
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772

Query: 321 VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSH 380
            P  P +  VP  P ++    GP ++P P    ++P    P ++P+P  P ++P P  SH
Sbjct: 773 QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESH 832

Query: 381 V 381
           +
Sbjct: 833 L 833



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 50/177 (28%), Positives = 78/177 (44%), Gaps = 27/177 (15%)

Query: 239 PQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVP------PGP 289
           P  P P V  + P+P    + P P   P++P P   P +P P  SR++P P      P P
Sbjct: 643 PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPP 702

Query: 290 RMAPVPPWP------------PMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMA 337
             +P  P P            P+ P+P  P + P   GP ++P P  P ++  P  P ++
Sbjct: 703 EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLS 762

Query: 338 RVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLP------PRSHVPHTGLAP 388
                P ++P P  P +  +P  P ++P   GP ++P P      P++  PH    P
Sbjct: 763 PQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 49/152 (32%), Positives = 73/152 (48%), Gaps = 14/152 (9%)

Query: 242 PRPPVL--PVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPPGSRMAPVPPGPRMAPVPP 296
           P  P L  P+ P P   P+ P     P++P P   P +P P  SR++P P    M+P P 
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586

Query: 297 WPPMAP-------VPPWP--PMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAP 347
             PM+P        PP+   P++P P   P++P P    ++  P   PM+  P   PM+P
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646

Query: 348 LPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRS 379
            P    ++PLP    ++P P   P++P P  S
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPPPEES 678



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 55/178 (30%), Positives = 74/178 (41%), Gaps = 21/178 (11%)

Query: 225 AAPALDPALCVHL---VPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMP---PMAPVPP 278
           A   L+P L   L   +P LP P   P+ P P   P  P P    ++P P   P +P+P 
Sbjct: 422 AGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPE 481

Query: 279 G---------SRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGP-PMAPVPPGPPMA 328
                     S ++P P    ++P P   P +P+   P   P  + P P    P  PP  
Sbjct: 482 ALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPE 541

Query: 329 RVPPGPPMARVPPGPPMAPLPPGPP-----MAPLPPGPPMAPLPPGPPMAPLPPRSHV 381
             P  PP    P  PP   LP  PP     ++P P   PM+P P   PM+P P  S +
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 50/182 (27%), Positives = 74/182 (40%), Gaps = 35/182 (19%)

Query: 230 DPALCV-----HLVPQLPRPPVLPVP------PMPPRPPMVPMPPRP------------P 266
           +P LC      HL P+   P + P P      P    P + P P  P            P
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSP 790

Query: 267 IAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPP--- 323
            A  P ++P P    ++P    P ++PVP  P ++P P    ++P    P ++P P    
Sbjct: 791 QAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESH 850

Query: 324 -GPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPL--------PPGPPMAP 374
             P + + P  P   + P  P   P P   P+ P P  P ++PL        P  PP++P
Sbjct: 851 LSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP 910

Query: 375 LP 376
           LP
Sbjct: 911 LP 912



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 42/148 (28%), Positives = 68/148 (45%), Gaps = 4/148 (2%)

Query: 231 PALCVHLVPQL-PRPPVLPVPPMPPRPPMVPMPPRPPIAPM---PPMAPVPPGSRMAPVP 286
           P L +   PQL PR     + P P  P + P P  P ++P    P ++P P    +  VP
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVP 783

Query: 287 PGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMA 346
             P ++P    P ++P P    ++P    P ++PVP  P ++  P    ++     P ++
Sbjct: 784 EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLS 843

Query: 347 PLPPGPPMAPLPPGPPMAPLPPGPPMAP 374
           P P    ++P    PP++P P  PP  P
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPPEEP 871



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 55/187 (29%), Positives = 73/187 (39%), Gaps = 42/187 (22%)

Query: 236  HLVPQLPRPPVLPVPPMPPRPP-MVPMPPRPPIAPMPPMAPVPP--GSRMAPVPPGPRMA 292
            HL P+L +PP+ P P  PP  P   P P   P+ P P    + P  G      P  P ++
Sbjct: 850  HLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLS 909

Query: 293  PVPPWPPMAPV--PPWPP--MAPVPTGPPMAPV--------------------------- 321
            P+P   P++P   P   P  M P P  PP++P+                           
Sbjct: 910  PLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP 969

Query: 322  --PPGPPMARVPPGPP----MARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPL 375
              P   P+   P  PP         P PPM  LPP P  +P+ P  P+   P  P  +PL
Sbjct: 970  ESPLAAPILETPISPPPEANCTDPEPVPPMI-LPPSPG-SPVGPASPILMEPLPPQCSPL 1027

Query: 376  PPRSHVP 382
               S VP
Sbjct: 1028 LQHSLVP 1034



 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 57/194 (29%), Positives = 74/194 (38%), Gaps = 53/194 (27%)

Query: 236  HLVPQL------PRP------PVLPVPPMPPRPPMVPMPPRPPIAPMP-PMAPVPPGSRM 282
            HL PQ       PRP      P L  PP+ PRP   P  P    AP   P+ P P    +
Sbjct: 832  HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL 891

Query: 283  APVPPGPRMAPVPPWPPMAPVPPWPP-------------MAPVPTGPPMAPV-----PP- 323
            +P+   P ++  P  PP++P+P   P             M P P  PP++P+     PP 
Sbjct: 892  SPLLGEPALSE-PGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPA 950

Query: 324  --------------GPPMARVPPGPPMARVPPGPP-----MAPLPPGPPMAPLPPGPPMA 364
                          G      P   P+   P  PP       P P  P + P  PG P+ 
Sbjct: 951  LSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVG 1010

Query: 365  PLPPGPPMAPLPPR 378
            P  P   M PLPP+
Sbjct: 1011 PASP-ILMEPLPPQ 1023



 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 50/176 (28%), Positives = 72/176 (40%), Gaps = 33/176 (18%)

Query: 227  PALDPALCVHLVPQLPRPPVLPVPPMPPRPP----------MVPMPPRPPIAPM------ 270
            P+L P L    + +   PP+ P+P   P  P          M P P  PP++P+      
Sbjct: 889  PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAP 948

Query: 271  PPMAPV-----PPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGP 325
            P ++P+     P G++    P  P  AP+    P++P P      P P  P + P  PG 
Sbjct: 949  PALSPLGELEYPFGAKGDSDPESPLAAPILE-TPISPPPEANCTDPEPVPPMILPPSPGS 1007

Query: 326  PMARVPPGPPMARVPPGPPMAPL------PPGPPMAPLPPGPPMAPLPPGPPMAPL 375
            P   V P  P+   P  P  +PL      P   P  P    PP  PL    P++P+
Sbjct: 1008 P---VGPASPILMEPLPPQCSPLLQHSLVPQNSP--PSQCSPPALPLSVPSPLSPI 1058



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 36/102 (35%), Positives = 42/102 (41%), Gaps = 21/102 (20%)

Query: 287  PGPRMAPV--------PPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMAR 338
            PGP+  P+        P  PP  P PP      + TGP + PV P PP       P   +
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPP----GALSTGPVLGPVHPTPP-------PSSPQ 4315

Query: 339  VPPGPPMAPLPPG--PPMAPLPPGPPMAPLPPGPPMAPLPPR 378
             P  P   P P    P  A LPP  P  P P GP + P P R
Sbjct: 4316 EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGR 4357



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 83/338 (24%), Positives = 114/338 (33%), Gaps = 50/338 (14%)

Query: 81   EPEQQQEEPPLTKPEQQQEEPPLLEL-------------KQEQEEPPQTTVE-----GPQ 122
            +P   Q +PPL  P QQQ++  LL                 E    P    +     G Q
Sbjct: 4085 QPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQ 4144

Query: 123  PAEGPQTAEGPQPP--ERKRRRRTAFTQFQ----LQELENFFDESQYPDVVARERLAARL 176
            P    Q   GPQ P  ER  +  T     +    LQ  +        P V    +L A+L
Sbjct: 4145 PGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTV---GQLRAQL 4201

Query: 177  NLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVH 236
                 +          + ++ Q +LM R    +        +       +P      C  
Sbjct: 4202 QGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQP 4261

Query: 237  LVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
             +   P P   P+  +   P       RP     PP  P PPG+    +  GP + PV P
Sbjct: 4262 QLGGFPGPQTGPLQELGAGP-------RPQ---GPPRLPAPPGA----LSTGPVLGPVHP 4307

Query: 297  WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPG---PP 353
             PP  P  P  P  P     P + +   P  A++PP  P    P GP + P PPG   P 
Sbjct: 4308 TPP--PSSPQEPKRPSQLPSPSSQL---PTEAQLPPTHPGTPKPQGPTLEP-PPGRVSPA 4361

Query: 354  MAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHI 391
             A L        L P  P   L        + L P H+
Sbjct: 4362 AAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHL 4399



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 46/159 (28%), Positives = 59/159 (37%), Gaps = 19/159 (11%)

Query: 240  QLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPG-PRMAPVPPWP 298
            +L  P V   P  P    + P  P   + P  P    PP   +AP PP  P +     + 
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP----PPAQALAPSPPSHPDI-----FR 2370

Query: 299  PMAPVPPW--PPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPP-----MAPLPPG 351
            P +   P+  PP+ P P  PP       PP  R  P  P +RVP  P       +PL P 
Sbjct: 2371 PGSYTDPYAQPPLTPRPQPPPPESCCALPP--RSLPSDPFSRVPASPQSQSSSQSPLTPR 2428

Query: 352  PPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVH 390
            P  A      P+ P    P     PP         AP+H
Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLH 2467



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 4/131 (3%)

Query: 258 MVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPP 317
           M P  P P      P+     G ++ P    P    +P  PP    P  PP    PT PP
Sbjct: 404 MQPKEPGPLQCEAKPLGKA--GVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP 461

Query: 318 MAPVPPGPPMARVPPGPPMARVPPGPPM--APLPPGPPMAPLPPGPPMAPLPPGPPMAPL 375
                  PP   +P  P    +    P+  +PL P P  +PL P P  +P  P       
Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521

Query: 376 PPRSHVPHTGL 386
           PP    P   L
Sbjct: 522 PPEESPPSPAL 532



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 6/139 (4%)

Query: 250 PPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPP----GPRMAPVPPWPPMAPVPP 305
           P   P    V    +P    +  M P  PG       P    G ++ P    P    +P 
Sbjct: 381 PTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPL 440

Query: 306 WPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPM--APLPPGPPM 363
            PP    P  PP    P  PP       PP   +P  P    L    P+  +PL P P  
Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500

Query: 364 APLPPGPPMAPLPPRSHVP 382
           +PL P P  +P  P    P
Sbjct: 501 SPLSPPPESSPFSPLEESP 519



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 43/139 (30%), Positives = 52/139 (37%), Gaps = 18/139 (12%)

Query: 237  LVPQLPRPPVLPVPPMPPRPPMVPMP-------PRPPIAPMPPMAPVPPGSRMAPVP--- 286
            L PQ P PP   + P PP  P +  P        +PP+ P P   P PP S  A  P   
Sbjct: 2347 LRPQEP-PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ--PPPPESCCALPPRSL 2403

Query: 287  PGPRMAPVPPWPP-----MAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPP 341
            P    + VP  P       +P+ P P  A      P+ P    P     PP  P +R P 
Sbjct: 2404 PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463

Query: 342  GPPMAPLPPGPPMAPLPPG 360
             P   P  P PP      G
Sbjct: 2464 APLHKPPRPQPPEVAFKAG 2482



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/182 (29%), Positives = 65/182 (35%), Gaps = 22/182 (12%)

Query: 219  LGGAYYAAPALDPALCVHLVPQL-PRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAP-- 275
            LGG     P +  A       Q+ P+ P L + P  P       PP   +AP PP  P  
Sbjct: 2316 LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP-------PPAQALAPSPPSHPDI 2368

Query: 276  VPPGSRMAPV---PPGPRMAPVPPWPPMAPVP---PWPPMAPVPTGPP-----MAPVPPG 324
              PGS   P    P  PR  P PP    A  P   P  P + VP  P       +P+ P 
Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR 2428

Query: 325  PPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHT 384
            P  A      P+      P     PP  P +  P  P   P  P PP       S + HT
Sbjct: 2429 PLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGS-LAHT 2487

Query: 385  GL 386
             L
Sbjct: 2488 SL 2489



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 69/273 (25%), Positives = 83/273 (30%), Gaps = 99/273 (36%)

Query: 206  TATADLAHPLDMFLGGAYYAAPALDPA--LCVHLVPQLP-----RPPVLPVPPMPPRPPM 258
            T  A L+   D FL     + P  D    L + L PQ+P     + P    P  P  P  
Sbjct: 2130 TTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRF 2189

Query: 259  VPMPPRPPIAPMPPMAPVPP---GSRMAP----------VPPG-PRMAPVPPWPPMAPVP 304
               PP  P  P P  AP  P   G+   P           PPG PR  P  P P + P  
Sbjct: 2190 PTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC 2249

Query: 305  PWPPMAPVPTGP---------PMAPVPP----------------------GPP------- 326
            P      VP  P         P+   PP                      GPP       
Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDS 2309

Query: 327  ----------------MARVPPGPPMARVPPGPPMAPL-----PPGPPMAPLPPG----- 360
                            + + P  P  ++V P  P   L     PP   +AP PP      
Sbjct: 2310 PSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF 2369

Query: 361  -----------PPMAPLPPGPP---MAPLPPRS 379
                       PP+ P P  PP      LPPRS
Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS 2402



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/114 (31%), Positives = 40/114 (35%), Gaps = 5/114 (4%)

Query: 261  MPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPW--PPMAPVP-PWPPMAPVPTGPP 317
            +PP+P     PP A  P     +P  P         +  PP   VP P  P       PP
Sbjct: 2106 IPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPP 2165

Query: 318  MAP--VPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPG 369
              P  VP   P    P  P   R P  PP  P  P P  AP  P    A   PG
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 2/57 (3%)

Query: 239  PQLPRPPVLPVPPMPPRPPMVPMP--PRPPIAPMPPMAPVPPGSRMAPVPPGPRMAP 293
            P+ P PP  P+ P P  PP  P+   P  P+A  P  +P+P  S      P PR  P
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 23/62 (37%), Positives = 25/62 (40%), Gaps = 10/62 (16%)

Query: 334  PPMARVPPGPPMAPLPPGPPMAPL----------PPGPPMAPLPPGPPMAPLPPRSHVPH 383
            PP    PP  P+AP P  PP  PL          PP P   PL   P  A   PR+  P 
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969

Query: 384  TG 385
             G
Sbjct: 4970 EG 4971



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 40/139 (28%), Positives = 53/139 (38%), Gaps = 13/139 (9%)

Query: 245  PVL--PVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAP------VPP 296
            P+L  P+ P P      P P  P I P  P +PV P S +   P  P+ +P      VP 
Sbjct: 976  PILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQ 1035

Query: 297  WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAP 356
              P  P    PP  P+    P++P+     ++       M       P  P       +P
Sbjct: 1036 NSP--PSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSP 1093

Query: 357  LPPGPPMAPLP-PGPPMAP 374
            LP   PM  L  P P  AP
Sbjct: 1094 LP--SPMGDLSCPAPSPAP 1110



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 26/67 (38%), Positives = 30/67 (44%), Gaps = 8/67 (11%)

Query: 298  PPMAPVPPWPPMAPVPTGPPMAPVP--PGPPMARVP-PGP-PMARVP----PGPPMAPLP 349
            PP  P PP  P+AP P  PP  P+   P  P+A  P P P P+A  P    P P   P  
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPE 4969

Query: 350  PGPPMAP 356
             G    P
Sbjct: 4970 EGEDSRP 4976



 Score = 36.6 bits (83), Expect = 0.042
 Identities = 26/79 (32%), Positives = 31/79 (39%), Gaps = 8/79 (10%)

Query: 247  LPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWP-PMAPVP- 304
            L V  +   PP  P PP  P+AP P   P  P   +  +P  P   P  P P P+A  P 
Sbjct: 4901 LDVRQLSAPPPEEPSPPPSPLAPSPASPPTEP---LVELPTEPLAEPPVPSPLPLASSPE 4957

Query: 305  ---PWPPMAPVPTGPPMAP 320
               P P   P   G    P
Sbjct: 4958 SARPKPRARPPEEGEDSRP 4976



 Score = 35.8 bits (81), Expect = 0.071
 Identities = 26/74 (35%), Positives = 32/74 (43%), Gaps = 10/74 (13%)

Query: 271  PPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWP-PMAPVPTGPPMAPVPPG---PP 326
            PP  P PP S +AP P  P      P  P+  +P  P    PVP+  P+A  P      P
Sbjct: 4910 PPEEPSPPPSPLAPSPASP------PTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963

Query: 327  MARVPPGPPMARVP 340
             AR P     +R P
Sbjct: 4964 RARPPEEGEDSRPP 4977



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 4/70 (5%)

Query: 250  PPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPP--WP 307
            PP  P PP  P+ P P   P  P+  +P  +     PP P   P+   P  A   P   P
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELP--TEPLAEPPVPSPLPLASSPESARPKPRARP 4967

Query: 308  PMAPVPTGPP 317
            P     + PP
Sbjct: 4968 PEEGEDSRPP 4977



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 32/83 (38%), Positives = 36/83 (43%), Gaps = 16/83 (19%)

Query: 320  PVPPGPPMARVPPGPPMA----RVP-PGPPMAPLPPGPPM-------APLPPGPPMAPLP 367
            P  PGP + R   G P+A    R+P PG P+ P P GP              GP   P P
Sbjct: 2838 PSTPGPELGRQALGSPLAGISTRLPGPGEPV-PGPAGPAQFIELRHNVQKGLGPGGTPFP 2896

Query: 368  -PGPPMAP-LPPRSHVPHTGLAP 388
              GPP  P   P S  PH  LAP
Sbjct: 2897 GQGPPQRPRFYPVSEDPHR-LAP 2918



 Score = 32.3 bits (72), Expect = 0.79
 Identities = 19/46 (41%), Positives = 20/46 (43%), Gaps = 1/46 (2%)

Query: 350  PGPPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLAPVHITWAP 395
            PGP   PL       P P GPP  P PP +      L PVH T  P
Sbjct: 4267 PGPQTGPLQE-LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP 4311



 Score = 32.3 bits (72), Expect = 0.79
 Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 7/73 (9%)

Query: 265  PPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPP- 323
            PP  P PP +P+ P     P  P   +    P  P+A  PP P   P+ + P  A   P 
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVEL----PTEPLAE-PPVPSPLPLASSPESARPKPR 4964

Query: 324  -GPPMARVPPGPP 335
              PP       PP
Sbjct: 4965 ARPPEEGEDSRPP 4977



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 25/77 (32%), Positives = 29/77 (37%), Gaps = 9/77 (11%)

Query: 298  PPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPL 357
            PP  P  P PP +P+   P     PP  P+  +P  P     PP P   PL   P  A  
Sbjct: 4909 PP--PEEPSPPPSPLAPSPAS---PPTEPLVELPTEP--LAEPPVPSPLPLASSPESA-- 4959

Query: 358  PPGPPMAPLPPGPPMAP 374
             P P   P   G    P
Sbjct: 4960 RPKPRARPPEEGEDSRP 4976



 Score = 29.3 bits (64), Expect = 6.7
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 4/73 (5%)

Query: 243  RPPVLPVPPMPPRPPMVPMPPR--PPIAPMPPMAPVPPGSR--MAPVPPGPRMAPVPPWP 298
            R P LP P MP +PP   +  R  P +A +     +  G     A + P     PV    
Sbjct: 3321 RQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQK 3380

Query: 299  PMAPVPPWPPMAP 311
            PM  +PP   M P
Sbjct: 3381 PMGTMPPSMCMKP 3393



 Score = 29.3 bits (64), Expect = 6.7
 Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 17/73 (23%)

Query: 83   EQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQ-----------------TTVEGPQPAE 125
            +QQQ++  L + +QQQ +    +L+Q+Q++  Q                  T+  PQ  +
Sbjct: 3932 QQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQ 3991

Query: 126  GPQTAEGPQPPER 138
              Q A GP  P +
Sbjct: 3992 QQQVALGPGMPAK 4004



 Score = 29.3 bits (64), Expect = 6.7
 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 2/36 (5%)

Query: 352  PPMAPLPPGPPMAPLPPGPPMAPLPPRSHVPHTGLA 387
            PP  P  P PP +PL P P   P  P   +P   LA
Sbjct: 4909 PP--PEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%)

Query: 98  QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145
           +EE   LE K+  E E+  + +++G   + A  PQ+ EG         P +RK+RR RT 
Sbjct: 165 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 224

Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205
           FT  QL+ELE  F+ + YPD+  RE LA R  LTE RVQVWF NRRA+W         R 
Sbjct: 225 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 275

Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264
            A A+     +  + G +   P   P L  + + +   +P  +P     P   +    P 
Sbjct: 276 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 333

Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305
           PP        P  P S  A   P  R        + VPP  P  P+ P
Sbjct: 334 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 381


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%)

Query: 98  QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145
           +EE   LE K+  E E+  + +++G   + A  PQ+ EG         P +RK+RR RT 
Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225

Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205
           FT  QL+ELE  F+ + YPD+  RE LA R  LTE RVQVWF NRRA+W         R 
Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276

Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264
            A A+     +  + G +   P   P L  + + +   +P  +P     P   +    P 
Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334

Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305
           PP        P  P S  A   P  R        + VPP  P  P+ P
Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%)

Query: 98  QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145
           +EE   LE K+  E E+  + +++G   + A  PQ+ EG         P +RK+RR RT 
Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225

Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205
           FT  QL+ELE  F+ + YPD+  RE LA R  LTE RVQVWF NRRA+W         R 
Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276

Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264
            A A+     +  + G +   P   P L  + + +   +P  +P     P   +    P 
Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334

Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305
           PP        P  P S  A   P  R        + VPP  P  P+ P
Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%)

Query: 98  QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145
           +EE   LE K+  E E+  + +++G   + A  PQ+ EG         P +RK+RR RT 
Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225

Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205
           FT  QL+ELE  F+ + YPD+  RE LA R  LTE RVQVWF NRRA+W         R 
Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276

Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264
            A A+     +  + G +   P   P L  + + +   +P  +P     P   +    P 
Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334

Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305
           PP        P  P S  A   P  R        + VPP  P  P+ P
Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%)

Query: 98  QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145
           +EE   LE K+  E E+  + +++G   + A  PQ+ EG         P +RK+RR RT 
Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225

Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205
           FT  QL+ELE  F+ + YPD+  RE LA R  LTE RVQVWF NRRA+W         R 
Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276

Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264
            A A+     +  + G +   P   P L  + + +   +P  +P     P   +    P 
Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334

Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305
           PP        P  P S  A   P  R        + VPP  P  P+ P
Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 75/228 (32%), Positives = 103/228 (45%), Gaps = 31/228 (13%)

Query: 98  QEEPPLLELKQ--EQEEPPQTTVEG--PQPAEGPQTAEGPQ-------PPERKRRR-RTA 145
           +EE   LE K+  E E+  + +++G   + A  PQ+ EG         P +RK+RR RT 
Sbjct: 166 EEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSRTT 225

Query: 146 FTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQRVLMLRN 205
           FT  QL+ELE  F+ + YPD+  RE LA R  LTE RVQVWF NRRA+W         R 
Sbjct: 226 FTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARW---------RK 276

Query: 206 TATADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLP-RPPVLPVPPMPPRPPMVPMPPR 264
            A A+     +  + G +   P   P L  + + +   +P  +P     P   +    P 
Sbjct: 277 QAGANQLMAFNHLIPGGF--PPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPL 334

Query: 265 PPIAPMPPMAPVPPGSRMAPVPPGPRM-------APVPPWPPMAPVPP 305
           PP        P  P S  A   P  R        + VPP  P  P+ P
Sbjct: 335 PPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNP 382


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 63/163 (38%), Positives = 71/163 (43%), Gaps = 33/163 (20%)

Query: 242 PRPPVLPVPPM------PPR--PPMVPMPPRPPIAPMP---PMAPVPPGSRMAPV----- 285
           P+PP+ P PP       PP+  PP  P P +PP  P P      P PP     PV     
Sbjct: 56  PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115

Query: 286 ---------PPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPP-MAPVPPGPPMARVPPGPP 335
                    PP    AP P  PP +  PP     P PT PP +   PPG P    PP PP
Sbjct: 116 GPAPGVGSAPPASSSAP-PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP----PPTPP 170

Query: 336 MARVPPGPPMAPLPPGPPMA-PLP-PGPPMAPLPPGPPMAPLP 376
            + VP  PP A  PP PP A P P PGP   P P GP    +P
Sbjct: 171 SSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMP 213



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 61/155 (39%), Positives = 67/155 (43%), Gaps = 21/155 (13%)

Query: 236 HLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAP--------VPP 287
           H  P  P+P     PP PP+    P+  + P  P P +   PP S  AP         PP
Sbjct: 85  HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP-GPAPGVGSAPPASSSAPPATPPTSGAPP 143

Query: 288 GPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVP---PGPP 344
           G    P P  PP   V   PP AP PT PP + VP  PP A  PP PP A VP   PGP 
Sbjct: 144 GSGPGPTPTPPPA--VTSAPPGAPPPT-PPSSGVPTTPPQAGGPP-PPPAAVPGPGPGPK 199

Query: 345 MAPLPPGP-----PMAPLPPGPPMAPLPPGPPMAP 374
             P P GP     P  P P G P    P G P  P
Sbjct: 200 QGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPP 234



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 62/156 (39%), Positives = 69/156 (44%), Gaps = 23/156 (14%)

Query: 255 RPPMVPMP----PRPPIAPMPP--MAPVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPP 308
           R PM P P    P+PPI P PP      PP  +  P  P P   P  P P     PP PP
Sbjct: 44  RGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPP 103

Query: 309 M----APVPTGPPMAP-VPPGPP-MARVPPG-PPMARVPP--GPPMAPLPP-----GPPM 354
                  V  GP  AP V   PP  +  PP  PP +  PP  GP   P PP      PP 
Sbjct: 104 QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPG 163

Query: 355 APLPPGPPMAPLPPGPPMA--PLPPRSHVPHTGLAP 388
           AP PP PP + +P  PP A  P PP + VP  G  P
Sbjct: 164 AP-PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP 198



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 47/144 (32%), Positives = 55/144 (38%), Gaps = 37/144 (25%)

Query: 277 PPGSRM----APVPPGPRMA----PVPPWPPMAPVPPWPPMAPVPTGPP--MAPVPPGPP 326
           PPG  +     P+ PGP  +    P+PP PP       PP  P P  PP    P  P P 
Sbjct: 35  PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPH 94

Query: 327 MARVPPGPP-----------------MARVPPG--------PPMAPLPPGPPMAPLP-PG 360
             + PP PP                 +   PP         PP +  PPG    P P P 
Sbjct: 95  QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPP 154

Query: 361 PPMAPLPPGPPMAPLPPRSHVPHT 384
           P +   PPG P  P PP S VP T
Sbjct: 155 PAVTSAPPGAP-PPTPPSSGVPTT 177



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/126 (34%), Positives = 46/126 (36%), Gaps = 29/126 (23%)

Query: 242 PRPPVLPVPP--MPPRPPMVPMPPRPPIA---PMPPMAPVPPGSRMAPVPPGPRMAPVPP 296
           P P V   PP   PP PP   +P  PP A   P PP A   PG       PGP+  P P 
Sbjct: 153 PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG-------PGPKQGPGPG 205

Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPP----GPPMARVPPGPP------MA 346
            P    +P      P P G P    P G P    PP    G P       PP        
Sbjct: 206 GPKGGKMPG----GPKPGGGPGLSTPGGHPK---PPHRGGGEPRGGRQHHPPYHQQHHQG 258

Query: 347 PLPPGP 352
           P P GP
Sbjct: 259 PPPGGP 264



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 9/100 (9%)

Query: 40  GGEDEENTRSKPEYGTEAENNVGTEGSVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQ- 98
           GG    +    P  G     N G  G  P     +       P QQQ++PP  +P  QQ 
Sbjct: 23  GGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82

Query: 99  ---EEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQP 135
              + PP  +  Q+Q+ PP      PQ +  P  A+GP P
Sbjct: 83  PPHQPPPHPQPHQQQQPPPP-----PQDSSKPVVAQGPGP 117



 Score = 36.2 bits (82), Expect = 0.055
 Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 3/78 (3%)

Query: 322 PPGPPMA--RVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPPRS 379
           PPG  +   R P GP   +  P PP+ P PP       PP  P    PP P   P  P+ 
Sbjct: 35  PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP-PHQPPPHPQP 93

Query: 380 HVPHTGLAPVHITWAPVI 397
           H       P   +  PV+
Sbjct: 94  HQQQQPPPPPQDSSKPVV 111


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 94/323 (29%), Positives = 117/323 (36%), Gaps = 83/323 (25%)

Query: 135 PPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKW 194
           P  ++RR RT FT +QL+ELE  F+ES YPDV  RE LA RL+L E RVQVWFQNRRAKW
Sbjct: 101 PGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKW 160

Query: 195 KRNQRVL------MLRNTATADLAHPLD-----------------------MFLGGAYYA 225
           ++ +            +  T     P+D                       +   G +  
Sbjct: 161 RKKENTKKGPGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQGRHLH 220

Query: 226 APALDPALCVHLVPQLPRPP----VLPVPPMPPRP----PMVPMPPRPPIAPMPPMAPVP 277
           +P     L +H  P          + P PP PP P    P          AP PP  P  
Sbjct: 221 SPG---GLSLHSAPSSDSDSGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPA 277

Query: 278 PGSRMAPVPPGPRMAPVPPWPPMAPVP-------PWPPMAPVPTG----PPMAP------ 320
           PG+      P  R    P   P  P         P   +A V  G    P  +P      
Sbjct: 278 PGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESL 337

Query: 321 VPPGPPMARVPPGPPMARV-----PPGPPMAP---------------LPPG--PPMAPLP 358
           +   PP  +       A        PG P AP                P G   P A L 
Sbjct: 338 LSDSPPRRKAASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALK 397

Query: 359 PGPPMAP----LPPGPPMAPLPP 377
            G  + P     PP P + P PP
Sbjct: 398 GGAGLEPAPKDAPPAPAVPPAPP 420



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 83/331 (25%), Positives = 98/331 (29%), Gaps = 55/331 (16%)

Query: 66  SVPSDDQDREGGGGHEPEQQQEEPPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAE 125
           S PS D D  GGGG  PE  +  PP  K                  EPP      P    
Sbjct: 229 SAPSSDSD-SGGGGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPGTCDPAFYP 287

Query: 126 GPQTAEGPQP-PERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARL-NLTEDRV 183
             ++  GPQP P R   +  A                    V A ER AA L   +   V
Sbjct: 288 SQRSGAGPQPRPGRPADKDAASC-------------GPGAAVAAVERGAAGLPKASPFSV 334

Query: 184 QVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLG-----------GAYYAAPALDPA 232
           +    +   + K         + A A  A  LD   G           G +   P   P 
Sbjct: 335 ESLLSDSPPRRKA-------ASNAAAAAAAGLDFAPGLPCAPRTLIGKGHFLLYPITQPL 387

Query: 233 LCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMA 292
               LVPQ        + P P   P           P P + P PP         GP  A
Sbjct: 388 --GFLVPQAALKGGAGLEPAPKDAP-----------PAPAVPPAPPAQASFGAFSGPGGA 434

Query: 293 PVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLP-PG 351
           P   +   +P     P AP P   P   +      A    G   A      P  P P P 
Sbjct: 435 PDSAFARRSPDAVASPGAPAPAPAPFRDLASAA--ATEGGGGDCADAGTAGPAPPPPAPS 492

Query: 352 PPMAPLPPGPPMAPL-----PPGPPMAPLPP 377
           P   P PP P   P       PG    P PP
Sbjct: 493 PRPGPRPPSPAEEPATCGVPEPGAAAGPSPP 523



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 38/137 (27%), Positives = 44/137 (32%), Gaps = 46/137 (33%)

Query: 297 WPPMAPVPPWPPMAPVPTGPPMAPVPP-GPPMARVPPGPP------------------MA 337
           +P   P+    P A +  G  + P P   PP   VPP PP                   A
Sbjct: 381 YPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFA 440

Query: 338 RVPPGPPMAPLPPGPPMAPL-----------------------PPGPPMAPLP-PGP-PM 372
           R  P    +P  P P  AP                        P  PP AP P PGP P 
Sbjct: 441 RRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPP 500

Query: 373 APL--PPRSHVPHTGLA 387
           +P   P    VP  G A
Sbjct: 501 SPAEEPATCGVPEPGAA 517


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.137    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,441,015
Number of Sequences: 37866
Number of extensions: 2706449
Number of successful extensions: 124177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1631
Number of HSP's successfully gapped in prelim test: 1632
Number of HSP's that attempted gapping in prelim test: 19579
Number of HSP's gapped (non-prelim): 35689
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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