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Search of human proteins with 116174738
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116174738 pappalysin 2 isoform 1 [Homo sapiens]
(1791 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116174738 pappalysin 2 isoform 1 [Homo sapiens] 3801 0.0
gi|116174734 pappalysin 2 isoform 2 [Homo sapiens] 1700 0.0
gi|38045915 pregnancy-associated plasma protein A preproprotein ... 1498 0.0
gi|148886654 polydom [Homo sapiens] 77 2e-13
gi|157419154 selectin P precursor [Homo sapiens] 76 3e-13
gi|168693643 decay accelerating factor for complement isoform 2 ... 74 1e-12
gi|10835143 decay accelerating factor for complement isoform 1 p... 74 1e-12
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 72 5e-12
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 72 5e-12
gi|187960042 selectin E precursor [Homo sapiens] 71 1e-11
gi|62739186 complement factor H isoform a precursor [Homo sapiens] 70 2e-11
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 59 6e-08
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 59 6e-08
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 54 1e-06
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 54 1e-06
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 54 1e-06
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 53 3e-06
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 52 7e-06
gi|117320518 complement factor H-related 4 [Homo sapiens] 50 2e-05
gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens] 49 3e-05
gi|54792787 complement factor H-related 3 [Homo sapiens] 48 1e-04
gi|4502503 complement component 4 binding protein, alpha chain p... 47 1e-04
gi|110611237 coagulation factor XIII B subunit precursor [Homo s... 47 1e-04
gi|148539593 sushi domain containing 4 isoform a [Homo sapiens] 47 1e-04
gi|62912468 complement component 4 binding protein, beta chain i... 47 2e-04
gi|62912466 complement component 4 binding protein, beta chain i... 47 2e-04
gi|62912464 complement component 4 binding protein, beta chain i... 47 2e-04
gi|62912462 complement component 4 binding protein, beta chain i... 47 2e-04
gi|4502505 complement component 4 binding protein, beta chain is... 47 2e-04
gi|42476320 sushi domain containing 1 [Homo sapiens] 47 2e-04
>gi|116174738 pappalysin 2 isoform 1 [Homo sapiens]
Length = 1791
Score = 3801 bits (9856), Expect = 0.0
Identities = 1791/1791 (100%), Positives = 1791/1791 (100%)
Query: 1 MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR 60
MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR
Sbjct: 1 MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR 60
Query: 61 ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG 120
ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG
Sbjct: 61 ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG 120
Query: 121 AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL 180
AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL
Sbjct: 121 AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL 180
Query: 181 NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN 240
NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN
Sbjct: 181 NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN 240
Query: 241 QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN 300
QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN
Sbjct: 241 QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN 300
Query: 301 NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ 360
NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ
Sbjct: 301 NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ 360
Query: 361 PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR 420
PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR
Sbjct: 361 PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR 420
Query: 421 GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV 480
GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV
Sbjct: 421 GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV 480
Query: 481 LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP 540
LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP
Sbjct: 481 LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP 540
Query: 541 IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC 600
IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC
Sbjct: 541 IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC 600
Query: 601 EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD 660
EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD
Sbjct: 601 EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD 660
Query: 661 SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA 720
SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA
Sbjct: 661 SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA 720
Query: 721 YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS 780
YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS
Sbjct: 721 YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS 780
Query: 781 ELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTES 840
ELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTES
Sbjct: 781 ELCREPEPTSDTCGFTRFPGAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTES 840
Query: 841 RKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSR 900
RKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSR
Sbjct: 841 RKPTPIPIPPMVIGQTNKSLTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSR 900
Query: 901 RVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHP 960
RVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHP
Sbjct: 901 RVCDSSGYWTPEEAVGPPDVDQPCEPSLQAWSPEVHLYHMNMTVPCPTEGCSLELLFQHP 960
Query: 961 VQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGV 1020
VQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGV
Sbjct: 961 VQADTLTLWVTSFFMESSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKLHVDGKVSGV 1020
Query: 1021 KVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVE 1080
KVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVE
Sbjct: 1021 KVYTFDERIEIDAALLTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVE 1080
Query: 1081 VTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCS 1140
VTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCS
Sbjct: 1081 VTPGQMYQYQVLAEAGGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCS 1140
Query: 1141 KVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHE 1200
KVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHE
Sbjct: 1141 KVCELEEGFNCVGEPSLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHE 1200
Query: 1201 DKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKE 1260
DKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKE
Sbjct: 1201 DKKKCPVSLVTGEPHSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKE 1260
Query: 1261 DEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQH 1320
DEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQH
Sbjct: 1261 DEVWLKVCFNRPGEARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQH 1320
Query: 1321 NPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNH 1380
NPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNH
Sbjct: 1321 NPLIINVTHHQNVLFHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNH 1380
Query: 1381 QGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPM 1440
QGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPM
Sbjct: 1381 QGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPM 1440
Query: 1441 QKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
QKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ
Sbjct: 1441 QKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
Query: 1501 GLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGY 1560
GLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGY
Sbjct: 1501 GLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGY 1560
Query: 1561 YVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVL 1620
YVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVL
Sbjct: 1561 YVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVL 1620
Query: 1621 NCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPL 1680
NCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPL
Sbjct: 1621 NCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPL 1680
Query: 1681 CVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADG 1740
CVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADG
Sbjct: 1681 CVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADG 1740
Query: 1741 WCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ 1791
WCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ
Sbjct: 1741 WCDTINNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLDECTCRDPKAEENQ 1791
>gi|116174734 pappalysin 2 isoform 2 [Homo sapiens]
Length = 827
Score = 1700 bits (4402), Expect = 0.0
Identities = 810/810 (100%), Positives = 810/810 (100%)
Query: 1 MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR 60
MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR
Sbjct: 1 MMCLKILRISLAILAGWALCSANSELGWTRKKSLVEREHLNQVLLEGERCWLGAKVRRPR 60
Query: 61 ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG 120
ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG
Sbjct: 61 ASPQHHLFGVYPSRAGNYLRPYPVGEQEIHHTGRSKPDTEGNAVSLVPPDLTENPAGLRG 120
Query: 121 AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL 180
AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL
Sbjct: 121 AVEEPAAPWVGDSPIGQSELLGDDDAYLGNQRSKESLGEAGIQKGSAMAATTTTAIFTTL 180
Query: 181 NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN 240
NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN
Sbjct: 181 NEPKPETQRRGWAKSRQRRQVWKRRAEDGQGDSGISSHFQPWPKHSLKHRVKKSPPEESN 240
Query: 241 QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN 300
QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN
Sbjct: 241 QNGGEGSYREAETFNSQVGLPILYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQN 300
Query: 301 NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ 360
NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ
Sbjct: 301 NPAIIAGVFDNCSHTVSDKGWALGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQ 360
Query: 361 PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR 420
PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR
Sbjct: 361 PGTWTHVAATYDGRHMALYVDGTQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFR 420
Query: 421 GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV 480
GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV
Sbjct: 421 GHLGTLVFWSTALPQSHFQHSSQHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV 480
Query: 481 LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP 540
LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP
Sbjct: 481 LQGFEPEPEILSPLQPPLCGQTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNP 540
Query: 541 IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC 600
IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC
Sbjct: 541 IVSEEQIRLQHEALNEAFSRYNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPEC 600
Query: 601 EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD 660
EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD
Sbjct: 601 EHPLTGYDGGDCRLQGRCYSWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPD 660
Query: 661 SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA 720
SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA
Sbjct: 661 SPKRAYMSVKELKEALQLNSTHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPA 720
Query: 721 YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS 780
YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS
Sbjct: 721 YYGMPGHTDTMIHEVGHVLGLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKS 780
Query: 781 ELCREPEPTSDTCGFTRFPGAPFTNYMSYT 810
ELCREPEPTSDTCGFTRFPGAPFTNYMSYT
Sbjct: 781 ELCREPEPTSDTCGFTRFPGAPFTNYMSYT 810
>gi|38045915 pregnancy-associated plasma protein A preproprotein [Homo
sapiens]
Length = 1627
Score = 1498 bits (3878), Expect = 0.0
Identities = 712/1546 (46%), Positives = 1008/1546 (65%), Gaps = 44/1546 (2%)
Query: 263 LYFSGRRERLLLRPEVLAEIPREAFTVEAWVKPEGGQNNPAIIAGVFDNCSHTVSDKGWA 322
LYFSGR E+L LR ++ E+PR+AFT++ W++ EGGQ +PA+I G++D CS+ D+GW
Sbjct: 97 LYFSGRGEQLRLRADL--ELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWV 154
Query: 323 LGIRSGKDKGKRDARFFFSLCTDRVKKATILISHSRYQPGTWTHVAATYDGRHMALYVDG 382
+GI + D+ +D R+FFSL TDR ++ T + +H Y PG W ++AATYDG+ M LYV+G
Sbjct: 155 VGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNG 214
Query: 383 TQVASSLDQSGPLNSPFMASCRSLLLGGDSSEDGHYFRGHLGTLVFWSTALPQSHFQHSS 442
QVA+S +Q G + SP C+ L+LGG + H +RG++ W A Q
Sbjct: 215 AQVATSGEQVGGIFSPLTQKCKVLMLGGSALN--HNYRGYIEHFSLWKVARTQREILSDM 272
Query: 443 QHSSGEEEATDLVLTASFEPVNTEWVPFRDEKYPRLEV--LQGFEPEPEILSPLQPPLCG 500
+ L+L +++ V W P +D P++E GF + + L+PPLCG
Sbjct: 273 ETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLD----TSLEPPLCG 328
Query: 501 QTVCDNVELISQYNGYWPLRGEKVIRYQVVNICDDEGLNPIVSEEQIRLQHEALNEAFSR 560
QT+CDN E+I+ YN R KV+RY+VVN+ +D+ NP V+ EQ+ QH L EAF +
Sbjct: 329 QTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQ 388
Query: 561 YNISWQLSVHQVHNSTLRHRVVLVNCEPSKIGNDHCDPECEHPLTGYDGGDCR-LQGRCY 619
YNISW+L V +V NS+LR R++L NC+ SKIG+++CDPEC H LTG+DGGDCR L+ +
Sbjct: 389 YNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAF 448
Query: 620 SWNRRDGLCHVECNNMLNDFDDGDCCDPQVADVRKTCFDPDSPKRAYMSVKELKEALQLN 679
+ +G+C ++CN +FD G+CCDP++ +V +TCFDPDSP RAY+ V ELK L+L+
Sbjct: 449 VKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLD 508
Query: 680 STHFLNIYFASSVREDLAGAATWPWDKDAVTHLGGIVLSPAYYGMPGHTDTMIHEVGHVL 739
+ LNI+FA S E+LAG ATWPWDK+A+ HLGGIVL+P++YGMPGHT TMIHE+GH L
Sbjct: 509 GSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSL 568
Query: 740 GLYHVFKGVSERESCNDPCKETVPSMETGDLCADTAPTPKSELCREPEPTSDTCGFTRFP 799
GLYHVF+G+SE +SC+DPC ET PS ETGDLC DT P PK + C +P P +DTCGF F
Sbjct: 569 GLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFF 628
Query: 800 GAPFTNYMSYTDDNCTDNFTPNQVARMHCYLDLVYQQWTESRKPTPIPIPPMVIGQTNKS 859
P+ N+MSY DD+CTD+FTPNQVARMHCYLDLVYQ W SRKP P+ + P V+G T S
Sbjct: 629 NTPYNNFMSYADDDCTDSFTPNQVARMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDS 688
Query: 860 LTIHWLPPISGVVYDRASGSLCGACTEDGTFRQYVHTASSRRVCDSSGYWTPEEAVGPPD 919
+T+ W PPI G ++R GS C C E QY ASS C SG+W+P EA G PD
Sbjct: 689 VTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCSPSGHWSPREAEGHPD 748
Query: 920 VDQPCEPSLQAWSPEVHLYHMNMTVPCP-TEGCSLELLFQHPVQADTLTLWVT--SFFME 976
V+QPC+ S++ WSP + + CP +GC LEL F +P+ ++LT+WVT S +
Sbjct: 749 VEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWD 808
Query: 977 SSQVLFDTEILLENKESVHLGPLDTFCDIPLTIKL-HVDGKVSGVKVYTFDERIEIDAAL 1035
SS + D ++L + +++ LGP + FCD+PLTI+L V +V G+++YT DE +EIDAA+
Sbjct: 809 SSGAVNDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAM 868
Query: 1036 LTSQPHSPLCSGCRPVRYQVLRDPPFASGLPVVVTHSHRKFTDVEVTPGQMYQYQVLAEA 1095
LTS +PLC C+P++Y+V+RDPP + ++ H +RKF D+++ G +YQY V+ +
Sbjct: 869 LTSTADTPLCLQCKPLKYKVVRDPPLQMDVASIL-HLNRKFVDMDLNLGSVYQYWVITIS 927
Query: 1096 GGELGEASPPLNHIHGAPYCGDGKVSERLGEECDDGDLVSGDGCSKVCELEEGFNCVGEP 1155
G E E SP + +IHG+ YCGDG + + GE+CDD + ++GDGCS C E FNC+ EP
Sbjct: 928 GTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSLFCRQEVSFNCIDEP 987
Query: 1156 SLCYMYEGDGICEPFERKTSIVDCGIYTPKGYLDQWATRAYSSHEDKKKCPVSLVTGEP- 1214
S CY ++GDG+CE FE+KTSI DCG+YTP+G+LDQWA+ A SH+D ++CP ++ G+P
Sbjct: 988 SRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFLDQWASNASVSHQD-QQCPGWVIIGQPA 1046
Query: 1215 HSLICTSYHPDLPNHRPLTGWFPCVASENETQDDRSEQPEGSLKKEDEVWLKVCFNRPGE 1274
S +C + DL W+PC S +Q + WL+ F++P
Sbjct: 1047 ASQVCRTKVIDLSEGISQHAWYPCTISYPYSQ-----------LAQTTFWLRAYFSQPMV 1095
Query: 1275 ARAIFIFLTTDGLVPGEHQQPTVTLYLTDVRGSNHSLGTYGLSCQHNPLIINVTHHQNVL 1334
A A+ + L TDG G+ +Q T+++ L D + +H LG + LSC++NPLII V H +
Sbjct: 1096 AAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCRNNPLIIPVVHDLSQP 1155
Query: 1335 FHHTTSVLLNFSSPRVGISAVALRTSSRIGLSAPSNCISEDEGQNHQGQSCIHRPCGKQD 1394
F+H+ +V ++FSSP V IS VALR+ S+C E + QSC+H C K D
Sbjct: 1156 FYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSC-QRGETYSPAEQSCVHFACEKTD 1214
Query: 1395 SCPSLLLDHADVVNCTSIGP-GLMKCAITCQRGFALQASSGQYIRPMQ--KEILLTCSSG 1451
CP L +++A +NC+S +C ++C+ G+ LQ + Q + +TC+ G
Sbjct: 1215 -CPELAVENAS-LNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEG 1272
Query: 1452 HWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLED 1511
W++ V+C PVDC +PD V A+FSC EGT F +CS C PA+L+G + LTC+ED
Sbjct: 1273 KWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMED 1332
Query: 1512 GLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVR 1571
GLWS PE C+L C APP + NA+L C ++ H VG+ CKY+CKPGY+V S+ K +
Sbjct: 1333 GLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSR-KSK 1391
Query: 1572 NKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNC-----NQER 1626
+ K QC + G W++G+C+PV C+PPPP F G+Y+CTNGF +S+C + C +Q
Sbjct: 1392 KRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGL 1451
Query: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS-VEYKCEQGYGIGAVCSPLCVIPP 1685
I C K+G W F +C+ +QG+C P+ELNS ++ +C GY IG+ C+ C+
Sbjct: 1452 GSNVIHCRKDGTWNGSFHVCQEMQGQC-SVPNELNSNLKLQCPDGYAIGSECATSCLDHN 1510
Query: 1686 SDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADGWCDTI 1745
S+ ++LP N+T + HW+ P +V+ +VCT +W+P P L+HC++ CEPF D +CD I
Sbjct: 1511 SESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAI 1570
Query: 1746 NNRAYCHYDGGDCCSSTLSSKKVIPFAADCDLD-ECTCRDPKAEEN 1790
NNRA+C+YDGGDCC+ST+ +KKV PF CDL +C CRDP+A+E+
Sbjct: 1571 NNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEH 1616
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 76.6 bits (187), Expect = 2e-13
Identities = 91/355 (25%), Positives = 130/355 (36%), Gaps = 66/355 (18%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSSGHWD-QNVSCLPVDCGVPDPSLVNYANFSCS 1480
TC GF L+ + + + ++G W C+PV C P P L N
Sbjct: 2858 TCNEGFLLEGARSR----------VCLANGSWSGATPDCVPVRCATP-PQLANGVTEGLD 2906
Query: 1481 EGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLP 1539
G F+K + C L G +P LTC DG W CK + C P + + P
Sbjct: 2907 YG--FMKEVTFHCHEGYILHG-APKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHG---FP 2960
Query: 1540 HCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEP 1597
+ H G +Y+C PGY + ++ + CL G W SC+P C
Sbjct: 2961 NGFSFIH--GGHIQYQCFPGYKLHGNSSRR---------CLSNGSWSGSSPSCLP--CRC 3007
Query: 1598 PPPVFEGMYECTNG--FSLDSQCVLNCNQEREKL---PILCTKEGLWTQEFKLCENLQ-G 1651
PV E Y NG F + C + + L I C +G W+ F CE+ G
Sbjct: 3008 STPVIE--YGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCG 3065
Query: 1652 ECPPPPSEL---------NSVEYKCEQGYGIGAVCSPLCVIPP--SDPVMLPENITADTL 1700
P P+ N + Y C GY I +C S P + E ++ +
Sbjct: 3066 SLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGS- 3124
Query: 1701 EHWMEPVKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQADGWCDTINNRAYCHYDG 1755
P V + V TG + V + C+ E + D DT C DG
Sbjct: 3125 -----PPSVANAVATGEAHTYESEVKLRCL---EGYTMDTDTDTFT----CQKDG 3167
Score = 72.8 bits (177), Expect = 3e-12
Identities = 78/314 (24%), Positives = 119/314 (37%), Gaps = 65/314 (20%)
Query: 1385 CIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEI 1444
CI C K PS+ + V+ G + + C GF L S+
Sbjct: 2078 CIAHFCEKP---PSVSYSILESVSKAKFAAGSV-VSFKCMEGFVLNTSAK---------- 2123
Query: 1445 LLTCS-SGHWD---QNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
+ C G W+ ++ C+PV CG P PS++N ++ F + SC ++
Sbjct: 2124 -IECMRGGQWNPSPMSIQCIPVRCGEP-PSIMN--GYASGSNYSFGAMVAYSCNKGFYIK 2179
Query: 1501 GLSPWLTCLEDGLWSLPEVYC-KLECDAPPIILNANLLLPHCLQDNHDVGTI----CKYE 1555
G TC G WS P C + C PP + N L H G I +Y+
Sbjct: 2180 G-EKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFL--------EHTTGRIFESEVRYQ 2230
Query: 1556 CKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGS---CIPVVCEPPPPVFEGMYECTNGF 1612
C PGY S C W S C+P+ C PPP+ G + N F
Sbjct: 2231 CNPGYKSVGSP---------VFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGEN-F 2280
Query: 1613 SLDSQCVLNCNQEREKL---PILCTKEGLWTQEFKLCENLQGECPPPP------------ 1657
+ S+ CN+ E + C K G W ++ + + +CP PP
Sbjct: 2281 EVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSN-PKCMPAKCPEPPLLENQLVLKELT 2339
Query: 1658 SELNSVEYKCEQGY 1671
+E+ V + C++G+
Sbjct: 2340 TEVGVVTFSCKEGH 2353
Score = 72.0 bits (175), Expect = 5e-12
Identities = 85/330 (25%), Positives = 119/330 (36%), Gaps = 72/330 (21%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANF 1477
K C +G+ L KE +S C PV C P+ +N +
Sbjct: 1868 KVTYRCNKGYTLAGD---------KESSCLANSSWSHSPPVCEPVKCSSPEN--INNGKY 1916
Query: 1478 SCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLE-CDAPPIILNANL 1536
S G +L S SC LQG S + C G+W C L C PP I +A +
Sbjct: 1917 ILS-GLTYLSTASYSCDTGYSLQGPSI-IECTASGIWDRAPPACHLVFCGEPPAIKDAVI 1974
Query: 1537 LLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGS--CIPVV 1594
+N Y CK GY +A L I+CL G W + C+ V
Sbjct: 1975 T-----GNNFTFRNTVTYTCKEGYTLAG---------LDTIECLADGKWSRSDQQCLAVS 2020
Query: 1595 CEPPPPVFEG-------------MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQ 1641
C+ PP V Y C++G+SL L CN + + +P EG Q
Sbjct: 2021 CDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVP----PEG---Q 2073
Query: 1642 EFKLCENLQGECPPPPSELNSV-EYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTL 1700
+ C + C PPS S+ E + + G+V S C+ E +T
Sbjct: 2074 DMPRC--IAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCM----------EGFVLNTS 2121
Query: 1701 EHWMEPVKVQSIVCTGRRQWHPDPVLVHCI 1730
I C QW+P P+ + CI
Sbjct: 2122 A---------KIECMRGGQWNPSPMSIQCI 2142
Score = 68.6 bits (166), Expect = 5e-11
Identities = 71/302 (23%), Positives = 108/302 (35%), Gaps = 88/302 (29%)
Query: 1447 TCSSGHWDQNV-SCLPVDCGVPD------------------------------------- 1468
TC W ++ +C+P+DCG+P
Sbjct: 2595 TCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHL 2654
Query: 1469 ----PSLVNYANFSCSEGTKFLKRCSIS--CVPPAKLQGLSPWLTCLEDGLWSLPEVYC- 1521
+ N + + FL +S C P +L G +P L C EDG W+ C
Sbjct: 2655 GAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLG-NPVLICQEDGTWNGSAPSCI 2713
Query: 1522 KLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLE 1581
+ECD P N L +G+ +Y CKPG+ +A S L++ CLE
Sbjct: 2714 SIECDLPTAPENGFLRFTET-----SMGSAVQYSCKPGHILAGSD--------LRL-CLE 2759
Query: 1582 GGIWEQGS--CIPVVCEPPPPVFEG-------MYECTNGFSLDSQCVLNCNQEREKLPIL 1632
W S C + C+ P PV G Y T + D VLN + R
Sbjct: 2760 NRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERR-----T 2814
Query: 1633 CTKEGLWTQEFKLCENLQGECPPPPSELN------------SVEYKCEQGYGIGAVCSPL 1680
C + W ++ +C + +C PP N +EY C +G+ + S +
Sbjct: 2815 CQDDKNWDEDEPIC--IPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRV 2872
Query: 1681 CV 1682
C+
Sbjct: 2873 CL 2874
Score = 60.1 bits (144), Expect = 2e-08
Identities = 66/266 (24%), Positives = 98/266 (36%), Gaps = 71/266 (26%)
Query: 1452 HW--DQNVSCLPVDCGVPDP---SLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWL 1506
HW + + C+P+DCG P P + NF +F C +L G S W
Sbjct: 2250 HWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFF------CNEGYELVGDSSW- 2302
Query: 1507 TCLEDGLW---SLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVA 1563
TC + G W S P+ +C PP++ N +L + +VG + + CK
Sbjct: 2303 TCQKSGKWNKKSNPKC-MPAKCPEPPLLENQLVL----KELTTEVGVV-TFSCK------ 2350
Query: 1564 ESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGM--------------YE 1607
EG V ++CL W C V+C PPP + G+ Y
Sbjct: 2351 ---EGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYS 2407
Query: 1608 CTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPP---------- 1657
C GF L R LC +G W+ C + ECP P
Sbjct: 2408 CVGGFFL-----------RGNSTTLCQPDGTWSSPLPEC--VPVECPQPEEIPNGIIDVQ 2454
Query: 1658 --SELNSVEYKCEQGYGIGAVCSPLC 1681
+ L++ Y C+ G+ + + LC
Sbjct: 2455 GLAYLSTALYTCKPGFELVGNTTTLC 2480
Score = 60.1 bits (144), Expect = 2e-08
Identities = 81/358 (22%), Positives = 119/358 (33%), Gaps = 86/358 (24%)
Query: 1451 GHWD---QNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSI--SCVPPAKLQGLSPW 1505
G W+ + SC PV CG P+ + G+K+ +I C P +L+G +
Sbjct: 3225 GTWEPPFSDESCSPVSCGKPESPEHGFV-----VGSKYTFESTIIYQCEPGYELEG-NRE 3278
Query: 1506 LTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAE 1564
C E+ WS CK C+ P LN + +N G Y C GY +
Sbjct: 3279 RVCQENRQWSGGVAICKETRCETPLEFLNGKADI-----ENRTTGPNVVYSCNRGYSLEG 3333
Query: 1565 SAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNC 1622
+E C E G W C P C P + E F +D + C
Sbjct: 3334 PSEA---------HCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKC 3384
Query: 1623 NQE---REKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS------------VEYKC 1667
+ + I C + WTQ CE + C PP N+ + Y C
Sbjct: 3385 REGFLLQGHGIITCNPDETWTQTSAKCEKI--SCGPPAHVENAIARGVHYQYGDMITYSC 3442
Query: 1668 EQGYGIGA----------------VCSPLCVIPPSDPVMLPENITADTLEHWM-----EP 1706
GY + +C +C P + + E WM EP
Sbjct: 3443 YSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEP 3502
Query: 1707 VKVQSIVCTGRRQWHPDPVLVHCIQSCEPFQAD---GWCDTINNRAYCH---YDGGDC 1758
+ + + GR C+ P+Q D GW + + A C +GG C
Sbjct: 3503 ICILPCLNGGR-----------CV---APYQCDCPPGWTGSRCHTAVCQSPCLNGGKC 3546
Score = 57.4 bits (137), Expect = 1e-07
Identities = 56/233 (24%), Positives = 82/233 (35%), Gaps = 68/233 (29%)
Query: 1477 FSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNAN 1535
FSC EG +L G++ +TCLE G W+ YCK + C P I N
Sbjct: 1813 FSCQEG--------------YQLMGVTK-ITCLESGEWNHLIPYCKAVSCGKPAIPENG- 1856
Query: 1536 LLLPHCLQD-NHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGS--CIP 1592
C+++ G+ Y C GY +A E CL W C P
Sbjct: 1857 -----CIEELAFTFGSKVTYRCNKGYTLAGDKES---------SCLANSSWSHSPPVCEP 1902
Query: 1593 VVCEPPPPVFEG-------------MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLW 1639
V C P + G Y C G+SL ++ CT G+W
Sbjct: 1903 VKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIE-----------CTASGIW 1951
Query: 1640 TQEFKLCENLQGECPPPPSEL----------NSVEYKCEQGYGIGAVCSPLCV 1682
+ C + PP + N+V Y C++GY + + + C+
Sbjct: 1952 DRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECL 2004
Score = 56.2 bits (134), Expect = 3e-07
Identities = 61/234 (26%), Positives = 87/234 (37%), Gaps = 36/234 (15%)
Query: 1469 PSLVNYANFSCSEGTKFLKRCSIS--CVPPAKLQGLSPWLTCLEDGLW--SLPEVYC-KL 1523
P V+Y+ KF +S C+ L S + C+ G W S + C +
Sbjct: 2086 PPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLN-TSAKIECMRGGQWNPSPMSIQCIPV 2144
Query: 1524 ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGG 1583
C PP I+N + N+ G + Y C G+Y+ K C G
Sbjct: 2145 RCGEPPSIMNG-----YASGSNYSFGAMVAYSCNKGFYIKGEK---------KSTCEATG 2190
Query: 1584 IWEQG--SCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKL--PI-LCTKEGL 1638
W +C PV C PP V G E T G +S+ CN + + P+ +C
Sbjct: 2191 QWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRH 2250
Query: 1639 WTQEFKL-CENLQGECPPPPS---------ELNS-VEYKCEQGYGIGAVCSPLC 1681
W E L C L PPP E+ S V++ C +GY + S C
Sbjct: 2251 WHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTC 2304
Score = 53.1 bits (126), Expect = 2e-06
Identities = 78/362 (21%), Positives = 128/362 (35%), Gaps = 102/362 (28%)
Query: 1385 CIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEI 1444
C+ C + + P+ ++D + L TC+ GF L ++
Sbjct: 2435 CVPVECPQPEEIPNGIIDVQGLAY-------LSTALYTCKPGFELVGNT----------T 2477
Query: 1445 LLTCSSGHW-DQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLS 1503
L +GHW +C ++C P L FS ++ + + + SC +L+G S
Sbjct: 2478 TLCGENGHWLGGKPTCKAIECLKPKEIL--NGKFSYTD-LHYGQTVTYSCNRGFRLEGPS 2534
Query: 1504 PWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYV 1562
LTCLE G W + C + CD+P I N + ++ G I Y C PG+ V
Sbjct: 2535 A-LTCLETGDWDVDAPSCNAIHCDSPQPIENGFVE-----GADYSYGAIIIYSCFPGFQV 2588
Query: 1563 AESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGMYECT----------- 1609
A A +Q E W +C+P+ C PP + G +CT
Sbjct: 2589 AGHA----------MQTCEESGWSSSIPTCMPIDCGLPPHIDFG--DCTKLKDDQGYFEQ 2636
Query: 1610 ------------------------------------NGFSLDSQCVLNCNQEREKL--PI 1631
+ F + CN E L P+
Sbjct: 2637 EDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPV 2696
Query: 1632 L-CTKEGLWTQEFKLCENLQGECPPPP----------SELNSVEYKCEQGYGIGAVCSPL 1680
L C ++G W C +++ + P P S ++V+Y C+ G+ + L
Sbjct: 2697 LICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRL 2756
Query: 1681 CV 1682
C+
Sbjct: 2757 CL 2758
Score = 49.3 bits (116), Expect = 3e-05
Identities = 59/253 (23%), Positives = 85/253 (33%), Gaps = 57/253 (22%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSE 1481
+C+ G LQ S +L S W+ + + P P L+++ S
Sbjct: 2348 SCKEGHVLQGPS----------VLKCLPSQQWNDSFPVCKIVLCTPPP-LISFGVPIPSS 2396
Query: 1482 GTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYC-KLECDAPPIILNANLLLPH 1540
F SCV L+G S L C DG WS P C +EC P I P+
Sbjct: 2397 ALHFGSTVKYSCVGGFFLRGNSTTL-CQPDGTWSSPLPECVPVECPQPEEI-------PN 2448
Query: 1541 CLQDNHDVGTICK--YECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCE 1596
+ D + + Y CKPG+ + + C E G W G +C + C
Sbjct: 2449 GIIDVQGLAYLSTALYTCKPGFELVGNTT---------TLCGENGHWLGGKPTCKAIECL 2499
Query: 1597 PPPPVFEGM-------------YECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEF 1643
P + G Y C GF L+ L C + G W +
Sbjct: 2500 KPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALT-----------CLETGDWDVDA 2548
Query: 1644 KLCENLQGECPPP 1656
C + + P P
Sbjct: 2549 PSCNAIHCDSPQP 2561
Score = 48.1 bits (113), Expect = 7e-05
Identities = 62/284 (21%), Positives = 101/284 (35%), Gaps = 81/284 (28%)
Query: 1478 SCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYC-KLECDAPPIILNANL 1536
+ SE K + ++ C P +L G +P CL G W+ P +C ++ C PP + N
Sbjct: 1643 TASEDLKPGSKVNLFCDPGFQLVG-NPVQYCLNQGQWTQPLPHCERISCGVPPPLENGF- 1700
Query: 1537 LLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW----------- 1585
H D + G+ Y+C GYY+ + ++ C + G W
Sbjct: 1701 ---HSADDFY-AGSTVTYQCNNGYYLLGDS---------RMFCTDNGSWNGVSPSCLDVD 1747
Query: 1586 ---------EQGSCIPV----VCEPPPPVFEGMYECT------------NG------FSL 1614
E SC+ V +C PP C NG +++
Sbjct: 1748 ECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTV 1807
Query: 1615 DSQCVLNCNQEREKL---PILCTKEGLWTQEFKLCENLQGECPPPP-----SEL-----N 1661
++ +C + + + I C + G W C+ + P P EL +
Sbjct: 1808 GAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGS 1867
Query: 1662 SVEYKCEQGYGIGAVCSPLCVI--------PPSDPVML--PENI 1695
V Y+C +GY + C+ P +PV PENI
Sbjct: 1868 KVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENI 1911
Score = 41.6 bits (96), Expect = 0.007
Identities = 53/233 (22%), Positives = 79/233 (33%), Gaps = 50/233 (21%)
Query: 1448 CSSGHWDQNVSCLPVDCGVPDPSLVNY-ANFSCSEGTKFLKRCSISCVPPAKLQGLSPWL 1506
C G+ +C V C P Y +C+ F C + C P L G S +
Sbjct: 362 CREGYRASGQTCELVHCPALKPPENGYFIQNTCNN--HFNAACGVRCHPGFDLVG-SSII 418
Query: 1507 TCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHD----------VGTICKYEC 1556
CL +GLWS E YC++ PH Q H T C C
Sbjct: 419 LCLPNGLWSGSESYCRVR------------TCPHLRQPKHGHISCSTREMLYKTTCLVAC 466
Query: 1557 KPGYYVAESAEGKVRNKLLKIQCLEGGIWE--QGSCIPVVC---EPPPPVFEGMYEC-TN 1610
GY + S K+ C W+ + C+ C + P V + C
Sbjct: 467 DEGYRLEGSD---------KLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQ 517
Query: 1611 GFSLDSQCVLNCNQ----EREKLPILCTKEGLWT--QEFKLCENLQG---ECP 1654
+ C ++C Q K + CT G W + +C++++ CP
Sbjct: 518 PAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCP 570
>gi|157419154 selectin P precursor [Homo sapiens]
Length = 830
Score = 76.3 bits (186), Expect = 3e-13
Identities = 93/392 (23%), Positives = 149/392 (38%), Gaps = 61/392 (15%)
Query: 1382 GQSCIH-RPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPM 1440
G C + R CG+ + +L++ + + S +C+ C G+ + P
Sbjct: 191 GPECEYVRECGELELPQHVLMNCSHPLGNFSFNS---QCSFHCTDGYQVNG-------PS 240
Query: 1441 QKEILLTCSSGHW-DQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKR---CSISCVPP 1496
+ E L +SG W ++ CL C P + N +C K + CS SC
Sbjct: 241 KLECL---ASGIWTNKPPQCLAAQC--PPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEG 295
Query: 1497 AKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYE 1555
L G + C G+W+ P CK ++C + H L G+ CK+E
Sbjct: 296 FALVGPEV-VQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTA-FAYGSSCKFE 353
Query: 1556 CKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVCEPPPPVFEGMYECT---N 1610
C+PGY V L ++C++ G W +C + CEP G +C+
Sbjct: 354 CQPGYRV---------RGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLR 404
Query: 1611 GFSLDSQCVLNCNQE---REKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKC 1667
F D+ C C + R + C G WT +C+ LQ + P P N C
Sbjct: 405 AFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVP---NEARVNC 461
Query: 1668 EQGYG---IGAVCSPLCVIPPSDPVMLPENITADTLE-----HWME-PVKVQSIVCTGRR 1718
+G +VCS C ++ ++L + A L+ +W P + Q+I CT
Sbjct: 462 SHPFGAFRYQSVCSFTC----NEGLLL---VGASVLQCLATGNWNSVPPECQAIPCTPLL 514
Query: 1719 QWHPDPVLVHCIQSCEPFQADGWCDTINNRAY 1750
P + C+Q C I + Y
Sbjct: 515 S--PQNGTMTCVQPLGSSSYKSTCQFICDEGY 544
Score = 57.8 bits (138), Expect = 9e-08
Identities = 68/309 (22%), Positives = 112/309 (36%), Gaps = 60/309 (19%)
Query: 1419 CAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWD------QNVSCLPVDCGVPDPSLV 1472
C CQ G+ ++ ++L SGHW + +SC P++ V
Sbjct: 350 CKFECQPGYRVRGL----------DMLRCIDSGHWSAPLPTCEAISCEPLESPV------ 393
Query: 1473 NYANFSCSEGTKFLK---RCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAP 1528
+ + CS + + CS C L+G + + C G W+ P C+ L+C
Sbjct: 394 -HGSMDCSPSLRAFQYDTNCSFRCAEGFMLRG-ADIVRCDNLGQWTAPAPVCQALQCQDL 451
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ- 1587
P+ A + H ++C + C G + ++ +QCL G W
Sbjct: 452 PVPNEARVNCSHPF-GAFRYQSVCSFTCNEGLLLVGASV---------LQCLATGNWNSV 501
Query: 1588 -GSCIPVVCEPPPPVFEGMYECTNGF---SLDSQCVLNCNQER-----EKLPILCTKEGL 1638
C + C P G C S S C C++ E+L CT+ G
Sbjct: 502 PPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLD--CTRSGR 559
Query: 1639 WTQEFKLCENLQGECP----PPPSELNSVEYKCEQGYGIGAVCSPLCVIPPSDPVMLPEN 1694
WT +CE + +CP P L+ + + E + +G+ C C + P N
Sbjct: 560 WTDSPPMCEAI--KCPELFAPEQGSLDCSDTRGE--FNVGSTCHFSC--DNGFKLEGPNN 613
Query: 1695 ITADTLEHW 1703
+ T W
Sbjct: 614 VECTTSGRW 622
Score = 37.7 bits (86), Expect = 0.10
Identities = 45/209 (21%), Positives = 71/209 (33%), Gaps = 45/209 (21%)
Query: 1396 CPSLLLDHADVVNCTSIGPGL---MKCAITCQRGFALQASSGQYIRPMQKEILLTCS-SG 1451
CP L ++C+ C +C GF L+ + + C+ SG
Sbjct: 572 CPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNN-----------VECTTSG 620
Query: 1452 HWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKR----------CSISCVPPAKLQG 1501
W +P P + A + +GT + + C C L G
Sbjct: 621 RWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIG 680
Query: 1502 LSPWLTCLEDGLWSLPEVYCK-LECDA----PPIILNANLLLPHCLQDNHDVGTICKYEC 1556
S L+C G W+ C+ ++C PI +N + L N G+IC + C
Sbjct: 681 DST-LSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLW-----GNFSYGSICSFHC 734
Query: 1557 KPGYYVAESAEGKVRNKLLKIQCLEGGIW 1585
EG++ N + C E G W
Sbjct: 735 ---------LEGQLLNGSAQTACQENGHW 754
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 74.3 bits (181), Expect = 1e-12
Identities = 64/256 (25%), Positives = 95/256 (37%), Gaps = 45/256 (17%)
Query: 1459 CLPV---DCGVP------DPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCL 1509
CLP DCG+P P+L +F E T +C S V K+ G + CL
Sbjct: 28 CLPAVWGDCGLPPDVPNAQPALEGRTSFP--EDTVITYKCEESFV---KIPGEKDSVICL 82
Query: 1510 EDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGK 1569
+ WS E +C C+ P + +A+L P+ Q+ VGT+ +YEC+PGY S
Sbjct: 83 KGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP- 141
Query: 1570 VRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQ--- 1624
K+ CL+ W C C P + G + G + +CN
Sbjct: 142 ------KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYK 195
Query: 1625 ---EREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN--------------SVEYKC 1667
++ W+ C + CP PP N SV Y C
Sbjct: 196 LFGSTSSFCLISGSSVQWSDPLPECREIY--CPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Query: 1668 EQGYGIGAVCSPLCVI 1683
+G+ + S C +
Sbjct: 254 NKGFTMIGEHSIYCTV 269
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 74.3 bits (181), Expect = 1e-12
Identities = 64/256 (25%), Positives = 95/256 (37%), Gaps = 45/256 (17%)
Query: 1459 CLPV---DCGVP------DPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCL 1509
CLP DCG+P P+L +F E T +C S V K+ G + CL
Sbjct: 28 CLPAVWGDCGLPPDVPNAQPALEGRTSFP--EDTVITYKCEESFV---KIPGEKDSVICL 82
Query: 1510 EDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGK 1569
+ WS E +C C+ P + +A+L P+ Q+ VGT+ +YEC+PGY S
Sbjct: 83 KGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSP- 141
Query: 1570 VRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQ--- 1624
K+ CL+ W C C P + G + G + +CN
Sbjct: 142 ------KLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYK 195
Query: 1625 ---EREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN--------------SVEYKC 1667
++ W+ C + CP PP N SV Y C
Sbjct: 196 LFGSTSSFCLISGSSVQWSDPLPECREIY--CPAPPQIDNGIIQGERDHYGYRQSVTYAC 253
Query: 1668 EQGYGIGAVCSPLCVI 1683
+G+ + S C +
Sbjct: 254 NKGFTMIGEHSIYCTV 269
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 72.0 bits (175), Expect = 5e-12
Identities = 96/389 (24%), Positives = 141/389 (36%), Gaps = 70/389 (17%)
Query: 1395 SCPSLL--LDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEILLTCSSGH 1452
SC L L H V+ ++ G K + C GF L+ SS + +L
Sbjct: 1707 SCDDFLGQLPHGRVLFPLNLQLGA-KVSFVCDEGFRLKGSSVSHC-------VLVGMRSL 1758
Query: 1453 WDQNVS-CLPVDCGVPDPSLVNYANFSCSEGT-KFLKRCSISCVPPA------KLQGLSP 1504
W+ +V C + C P P+++N + G + K S +C P L G S
Sbjct: 1759 WNNSVPVCEHIFCPNP-PAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1817
Query: 1505 WLTCLED----GLWSLPEVYCKLE-----CDAPPIILNANLLLPHCLQD-NHDVGTICKY 1554
+ C D G+WS P C+L C P A+ +P + D VGT Y
Sbjct: 1818 -IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIP--INDFEFPVGTSLNY 1874
Query: 1555 ECKPGYYVAESAEGKVRNKLLKIQCLEGGIWE--QGSCIPVVCEPPPPVFEGMYECTNGF 1612
EC+PGY+ K+ I CLE +W + +C C PPP F GM
Sbjct: 1875 ECRPGYF----------GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDT 1924
Query: 1613 SLDSQCVLNCNQEREKL---PILCTKEG---LWTQEFKLCENLQGECPPPPSELNSVEYK 1666
S +CN+ + C G W ++ +CE + C PPP+ N Y
Sbjct: 1925 QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEII--SCEPPPTISNGDFYS 1982
Query: 1667 CEQ-GYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQ----WH 1721
+ + G V + C P E E V +SI CT + W
Sbjct: 1983 NNRTSFHNGTVVTYQCHTGPDG-------------EQLFELVGERSIYCTSKDDQVGVWS 2029
Query: 1722 PDPVLVHCIQSCEPFQADGWCDTINNRAY 1750
P C + + NR++
Sbjct: 2030 SPPPRCISTNKCTAPEVENAIRVPGNRSF 2058
Score = 59.3 bits (142), Expect = 3e-08
Identities = 90/402 (22%), Positives = 136/402 (33%), Gaps = 117/402 (29%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYAN 1476
K C GF L+ SS Y +L W+ +V C + C P P ++
Sbjct: 381 KVDFVCDEGFQLKGSSASYC-------VLAGMESLWNSSVPVCEQIFC--PSPPVIPNGR 431
Query: 1477 FSCS--EGTKFLKRCSISCVPPAKLQGLS------PWLTCLED----GLWSLPEVYCKL- 1523
+ E F K + +C P +G S + C D G+WS P C +
Sbjct: 432 HTGKPLEVFPFGKTVNYTCDPHPD-RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 490
Query: 1524 -ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEG 1582
C AP L A L D +GT KYEC+P YY + I CL+
Sbjct: 491 GHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYY----------GRPFSITCLDN 539
Query: 1583 GIWE--QGSCIPVVCEPPPPVFEGM--------------YECTNGFSLDSQCVLNCNQER 1626
+W + C C+ PP GM Y CT G L C
Sbjct: 540 LVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC---- 595
Query: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG- 1670
IL W+ + +C+ + C PP+ N V Y+C G
Sbjct: 596 ----ILSGNAAHWSTKPPICQRI--PCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS 649
Query: 1671 ----------------------YGIGAVCSPLCVIP-------PSDPVMLPENITA---- 1697
GI + +P C+IP + +++ +N +
Sbjct: 650 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 709
Query: 1698 DTLEHWMEPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+ +E +P V + + C +W P+ L C + C+P
Sbjct: 710 EVVEFRCQPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 749
Score = 59.3 bits (142), Expect = 3e-08
Identities = 90/402 (22%), Positives = 136/402 (33%), Gaps = 117/402 (29%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYAN 1476
K C GF L+ SS Y +L W+ +V C + C P P ++
Sbjct: 831 KVDFVCDEGFQLKGSSASYC-------VLAGMESLWNSSVPVCEQIFC--PSPPVIPNGR 881
Query: 1477 FSCS--EGTKFLKRCSISCVPPAKLQGLS------PWLTCLED----GLWSLPEVYCKL- 1523
+ E F K + +C P +G S + C D G+WS P C +
Sbjct: 882 HTGKPLEVFPFGKTVNYTCDPHPD-RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 940
Query: 1524 -ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEG 1582
C AP L A L D +GT KYEC+P YY + I CL+
Sbjct: 941 GHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYY----------GRPFSITCLDN 989
Query: 1583 GIWE--QGSCIPVVCEPPPPVFEGM--------------YECTNGFSLDSQCVLNCNQER 1626
+W + C C+ PP GM Y CT G L C
Sbjct: 990 LVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC---- 1045
Query: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG- 1670
IL W+ + +C+ + C PP+ N V Y+C G
Sbjct: 1046 ----ILSGNAAHWSTKPPICQRI--PCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS 1099
Query: 1671 ----------------------YGIGAVCSPLCVIP-------PSDPVMLPENITA---- 1697
GI + +P C+IP + +++ +N +
Sbjct: 1100 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 1159
Query: 1698 DTLEHWMEPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+ +E +P V + + C +W P+ L C + C+P
Sbjct: 1160 EVVEFRCQPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 1199
Score = 58.9 bits (141), Expect = 4e-08
Identities = 90/402 (22%), Positives = 136/402 (33%), Gaps = 117/402 (29%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYAN 1476
K C GF L+ SS Y +L W+ +V C + C P P ++
Sbjct: 1281 KVDFVCDEGFQLKGSSASYC-------VLAGMESLWNSSVPVCEQIFC--PSPPVIPNGR 1331
Query: 1477 FSCS--EGTKFLKRCSISCVPPAKLQGLS------PWLTCLED----GLWSLPEVYCKL- 1523
+ E F K + +C P +G S + C D G+WS P C +
Sbjct: 1332 HTGKPLEVFPFGKAVNYTCDPHPD-RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 1390
Query: 1524 -ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEG 1582
C AP L A L D +GT KYEC+P YY + I CL+
Sbjct: 1391 GHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYY----------GRPFSITCLDN 1439
Query: 1583 GIWE--QGSCIPVVCEPPPPVFEGM--------------YECTNGFSLDSQCVLNCNQER 1626
+W + C C+ PP GM Y CT G L C
Sbjct: 1440 LVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC---- 1495
Query: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG- 1670
IL W+ + +C+ + C PP+ N V Y+C G
Sbjct: 1496 ----ILSGNTAHWSTKPPICQRI--PCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGS 1549
Query: 1671 ----------------------YGIGAVCSPLCVIP-------PSDPVMLPENITA---- 1697
GI + +P C+IP + +++ +N +
Sbjct: 1550 RGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 1609
Query: 1698 DTLEHWMEPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+ +E +P V + + C +W P+ L C + C+P
Sbjct: 1610 EVVEFRCQPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 1649
Score = 51.2 bits (121), Expect = 9e-06
Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 55/247 (22%)
Query: 1466 VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQG-LSPWLTCLEDGLWSLPEVYCKLE 1524
+ D + + N+SC+ G + + S C+ L G + W T P + ++
Sbjct: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECI----LSGNAAHWST--------KPPICQRIP 615
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLL---KIQCLE 1581
C PP I N + + + ++N G++ Y C PG + G+ +L+ I C
Sbjct: 616 CGLPPTIANGDFISTN--RENFHYGSVVTYRCNPG------SGGRKVFELVGEPSIYCTS 667
Query: 1582 G----GIWEQGS---CIPVVCEPPPPVFEGMYECTNG--FSLDSQCVLNCNQE---REKL 1629
GIW + IP C PP V G+ N FSL+ C +
Sbjct: 668 NDDQVGIWSGPAPQCIIPNKCTPPN-VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 1630 PILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQGYGIG 1674
+ C W E C + C PPP L++ V Y CE GY +
Sbjct: 727 RVKCQALNKWEPELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 783
Query: 1675 AVCSPLC 1681
S C
Sbjct: 784 GAASMRC 790
Score = 51.2 bits (121), Expect = 9e-06
Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 55/247 (22%)
Query: 1466 VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQG-LSPWLTCLEDGLWSLPEVYCKLE 1524
+ D + + N+SC+ G + + S C+ L G + W T P + ++
Sbjct: 1018 ITDIQVGSRINYSCTTGHRLIGHSSAECI----LSGNAAHWST--------KPPICQRIP 1065
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLL---KIQCLE 1581
C PP I N + + + ++N G++ Y C PG + G+ +L+ I C
Sbjct: 1066 CGLPPTIANGDFISTN--RENFHYGSVVTYRCNPG------SGGRKVFELVGEPSIYCTS 1117
Query: 1582 G----GIWEQGS---CIPVVCEPPPPVFEGMYECTNG--FSLDSQCVLNCNQE---REKL 1629
GIW + IP C PP V G+ N FSL+ C +
Sbjct: 1118 NDDQVGIWSGPAPQCIIPNKCTPPN-VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 1176
Query: 1630 PILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQGYGIG 1674
+ C W E C + C PPP L++ V Y CE GY +
Sbjct: 1177 RVKCQALNKWEPELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 1233
Query: 1675 AVCSPLC 1681
S C
Sbjct: 1234 GAASMRC 1240
Score = 51.2 bits (121), Expect = 9e-06
Identities = 48/186 (25%), Positives = 67/186 (36%), Gaps = 39/186 (20%)
Query: 1493 CVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTIC 1552
C P + G S + C +G W +C C PP IL+ L H QDN G
Sbjct: 2069 CQPGFVMVG-SHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSH--QDNFSPGQEV 2125
Query: 1553 KYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCE------PPPPVF-- 1602
Y C+P Y + +A + C G W E C C+ P V
Sbjct: 2126 FYSCEPSYDLRGAA---------SLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLP 2176
Query: 1603 -------EGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPP 1655
+ + C GF L + +C +L + LW +CE + CP
Sbjct: 2177 LNLQLGAKVSFVCDEGFRLKGRSASHC--------VLAGMKALWNSSVPVCEQI--FCPN 2226
Query: 1656 PPSELN 1661
PP+ LN
Sbjct: 2227 PPAILN 2232
Score = 50.8 bits (120), Expect = 1e-05
Identities = 59/235 (25%), Positives = 87/235 (37%), Gaps = 47/235 (20%)
Query: 1481 EGTKFLKRCSISCVPPAKLQGLSPWLTCLEDG---LWSLPEVYC-KLECDAPPIILNANL 1536
+G +F + SC +L G S TC+ G +W C ++ C PP I N +
Sbjct: 119 KGIQFGSQIKYSCTKGYRLIGSSS-ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDF 177
Query: 1537 LLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLL---KIQCLEG----GIWEQGS 1589
+ + ++N G++ Y C PG + G+ +L+ I C GIW +
Sbjct: 178 ISTN--RENFHYGSVVTYRCNPG------SGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 1590 ---CIPVVCEPPPPVFEGMYECTNG--FSLDSQCVLNCNQE---REKLPILCTKEGLWTQ 1641
IP C PP V G+ N FSL+ C + + C W
Sbjct: 230 PQCIIPNKCTPPN-VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 288
Query: 1642 EFKLCENLQGECPPPPSELNS---------------VEYKCEQGYGIGAVCSPLC 1681
E C + C PPP L++ V Y CE GY + S C
Sbjct: 289 ELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 340
Score = 48.5 bits (114), Expect = 6e-05
Identities = 59/275 (21%), Positives = 96/275 (34%), Gaps = 80/275 (29%)
Query: 1524 ECDAPPIILNANLLLPHCLQDNHD--VGTICKYECKPGYYVAESAEGKVRNKLLKIQCLE 1581
+C+AP + A P L D + +GT YEC+PGY + I CL+
Sbjct: 42 QCNAPEWLPFAR---PTNLTDEFEFPIGTYLNYECRPGY----------SGRPFSIICLK 88
Query: 1582 GGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKL---PILCTKE 1636
+W + C C PP GM G SQ +C + + C
Sbjct: 89 NSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS 148
Query: 1637 G---LWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG-------- 1670
G +W E +C+ + C PP+ N V Y+C G
Sbjct: 149 GDTVIWDNETPICDRI--PCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFE 206
Query: 1671 ---------------YGIGAVCSPLCVIP-------PSDPVMLPENITA----DTLEHWM 1704
GI + +P C+IP + +++ +N + + +E
Sbjct: 207 LVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 266
Query: 1705 EPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+P V + + C +W P+ L C + C+P
Sbjct: 267 QPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 299
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/233 (26%), Positives = 80/233 (34%), Gaps = 58/233 (24%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 1602 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 1650
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--E 1586
P IL+ H QDN G Y C+PGY + +A + C G W E
Sbjct: 1651 PEILHGEHTPSH--QDNFSPGQEVFYSCEPGYDLRGAA---------SLHCTPQGDWSPE 1699
Query: 1587 QGSCIPVVCE------PPPPVF---------EGMYECTNGFSLDSQCVLNCNQEREKLPI 1631
C C+ P V + + C GF L V +C +
Sbjct: 1700 APRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHC--------V 1751
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQG---YG--IGAVCSP 1679
L LW +CE++ CP PP+ LN G YG I C P
Sbjct: 1752 LVGMRSLWNNSVPVCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDP 1802
Score = 38.5 bits (88), Expect = 0.059
Identities = 51/206 (24%), Positives = 70/206 (33%), Gaps = 53/206 (25%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 252 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 300
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG 1588
P +L+A +DN G Y C+PGY + +A ++C G W
Sbjct: 301 PDVLHAERTQRD--KDNFSPGQEVFYSCEPGYDLRGAA---------SMRCTPQGDWSPA 349
Query: 1589 --SCIPVVCEP------------PPPVFEGM---YECTNGFSLDSQCVLNCNQEREKLPI 1631
+C C+ P + G + C GF L C +
Sbjct: 350 APTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC--------V 401
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPP 1657
L E LW +CE + CP PP
Sbjct: 402 LAGMESLWNSSVPVCEQI--FCPSPP 425
Score = 38.5 bits (88), Expect = 0.059
Identities = 51/206 (24%), Positives = 70/206 (33%), Gaps = 53/206 (25%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 702 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 750
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG 1588
P +L+A +DN G Y C+PGY + +A ++C G W
Sbjct: 751 PDVLHAERTQRD--KDNFSPGQEVFYSCEPGYDLRGAA---------SMRCTPQGDWSPA 799
Query: 1589 --SCIPVVCEP------------PPPVFEGM---YECTNGFSLDSQCVLNCNQEREKLPI 1631
+C C+ P + G + C GF L C +
Sbjct: 800 APTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC--------V 851
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPP 1657
L E LW +CE + CP PP
Sbjct: 852 LAGMESLWNSSVPVCEQI--FCPSPP 875
Score = 38.5 bits (88), Expect = 0.059
Identities = 51/206 (24%), Positives = 70/206 (33%), Gaps = 53/206 (25%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 1152 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 1200
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG 1588
P +L+A +DN G Y C+PGY + +A ++C G W
Sbjct: 1201 PDVLHAERTQRD--KDNFSPGQEVFYSCEPGYDLRGAA---------SMRCTPQGDWSPA 1249
Query: 1589 --SCIPVVCEP------------PPPVFEGM---YECTNGFSLDSQCVLNCNQEREKLPI 1631
+C C+ P + G + C GF L C +
Sbjct: 1250 APTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC--------V 1301
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPP 1657
L E LW +CE + CP PP
Sbjct: 1302 LAGMESLWNSSVPVCEQI--FCPSPP 1325
Score = 31.2 bits (69), Expect = 9.5
Identities = 53/233 (22%), Positives = 77/233 (33%), Gaps = 63/233 (27%)
Query: 1476 NFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNA 1534
+F C EG + R + CV L G+ LW+ C+ + C PP ILN
Sbjct: 2186 SFVCDEGFRLKGRSASHCV----LAGMK--------ALWNSSVPVCEQIFCPNPPAILNG 2233
Query: 1535 NLLLPHCLQDNHDV--GTICKYECKPGYYVAESAEGKVRNKL--LKIQCLE----GGIWE 1586
H D+ G Y C G N + I+C G+W
Sbjct: 2234 R----HTGTPFGDIPYGKEISYACD-----THPDRGMTFNLIGESSIRCTSDPQGNGVWS 2284
Query: 1587 QGS-----CIPVVCEPPPPVFEGMY----------ECTNGFSLDSQCVLNCNQEREKLPI 1631
+ +P C PP + G Y T + D +L K I
Sbjct: 2285 SPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLV-----GKGFI 2339
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPPSELNS-------------VEYKCEQGY 1671
CT +G+W+Q C+ + P + ++ V KCE GY
Sbjct: 2340 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGY 2392
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 72.0 bits (175), Expect = 5e-12
Identities = 96/389 (24%), Positives = 141/389 (36%), Gaps = 70/389 (17%)
Query: 1395 SCPSLL--LDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEILLTCSSGH 1452
SC L L H V+ ++ G K + C GF L+ SS + +L
Sbjct: 1257 SCDDFLGQLPHGRVLFPLNLQLGA-KVSFVCDEGFRLKGSSVSHC-------VLVGMRSL 1308
Query: 1453 WDQNVS-CLPVDCGVPDPSLVNYANFSCSEGT-KFLKRCSISCVPPA------KLQGLSP 1504
W+ +V C + C P P+++N + G + K S +C P L G S
Sbjct: 1309 WNNSVPVCEHIFCPNP-PAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGEST 1367
Query: 1505 WLTCLED----GLWSLPEVYCKLE-----CDAPPIILNANLLLPHCLQD-NHDVGTICKY 1554
+ C D G+WS P C+L C P A+ +P + D VGT Y
Sbjct: 1368 -IRCTSDPHGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIP--INDFEFPVGTSLNY 1424
Query: 1555 ECKPGYYVAESAEGKVRNKLLKIQCLEGGIWE--QGSCIPVVCEPPPPVFEGMYECTNGF 1612
EC+PGY+ K+ I CLE +W + +C C PPP F GM
Sbjct: 1425 ECRPGYF----------GKMFSISCLENLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDT 1474
Query: 1613 SLDSQCVLNCNQEREKL---PILCTKEG---LWTQEFKLCENLQGECPPPPSELNSVEYK 1666
S +CN+ + C G W ++ +CE + C PPP+ N Y
Sbjct: 1475 QFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICEII--SCEPPPTISNGDFYS 1532
Query: 1667 CEQ-GYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCTGRRQ----WH 1721
+ + G V + C P E E V +SI CT + W
Sbjct: 1533 NNRTSFHNGTVVTYQCHTGPDG-------------EQLFELVGERSIYCTSKDDQVGVWS 1579
Query: 1722 PDPVLVHCIQSCEPFQADGWCDTINNRAY 1750
P C + + NR++
Sbjct: 1580 SPPPRCISTNKCTAPEVENAIRVPGNRSF 1608
Score = 59.3 bits (142), Expect = 3e-08
Identities = 90/402 (22%), Positives = 136/402 (33%), Gaps = 117/402 (29%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYAN 1476
K C GF L+ SS Y +L W+ +V C + C P P ++
Sbjct: 381 KVDFVCDEGFQLKGSSASYC-------VLAGMESLWNSSVPVCEQIFC--PSPPVIPNGR 431
Query: 1477 FSCS--EGTKFLKRCSISCVPPAKLQGLS------PWLTCLED----GLWSLPEVYCKL- 1523
+ E F K + +C P +G S + C D G+WS P C +
Sbjct: 432 HTGKPLEVFPFGKTVNYTCDPHPD-RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 490
Query: 1524 -ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEG 1582
C AP L A L D +GT KYEC+P YY + I CL+
Sbjct: 491 GHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYY----------GRPFSITCLDN 539
Query: 1583 GIWE--QGSCIPVVCEPPPPVFEGM--------------YECTNGFSLDSQCVLNCNQER 1626
+W + C C+ PP GM Y CT G L C
Sbjct: 540 LVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC---- 595
Query: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG- 1670
IL W+ + +C+ + C PP+ N V Y+C G
Sbjct: 596 ----ILSGNAAHWSTKPPICQRI--PCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGS 649
Query: 1671 ----------------------YGIGAVCSPLCVIP-------PSDPVMLPENITA---- 1697
GI + +P C+IP + +++ +N +
Sbjct: 650 GGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 709
Query: 1698 DTLEHWMEPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+ +E +P V + + C +W P+ L C + C+P
Sbjct: 710 EVVEFRCQPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 749
Score = 58.9 bits (141), Expect = 4e-08
Identities = 90/402 (22%), Positives = 136/402 (33%), Gaps = 117/402 (29%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYAN 1476
K C GF L+ SS Y +L W+ +V C + C P P ++
Sbjct: 831 KVDFVCDEGFQLKGSSASYC-------VLAGMESLWNSSVPVCEQIFC--PSPPVIPNGR 881
Query: 1477 FSCS--EGTKFLKRCSISCVPPAKLQGLS------PWLTCLED----GLWSLPEVYCKL- 1523
+ E F K + +C P +G S + C D G+WS P C +
Sbjct: 882 HTGKPLEVFPFGKAVNYTCDPHPD-RGTSFDLIGESTIRCTSDPQGNGVWSSPAPRCGIL 940
Query: 1524 -ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEG 1582
C AP L A L D +GT KYEC+P YY + I CL+
Sbjct: 941 GHCQAPDHFLFAKLKTQTNASD-FPIGTSLKYECRPEYY----------GRPFSITCLDN 989
Query: 1583 GIWE--QGSCIPVVCEPPPPVFEGM--------------YECTNGFSLDSQCVLNCNQER 1626
+W + C C+ PP GM Y CT G L C
Sbjct: 990 LVWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAEC---- 1045
Query: 1627 EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG- 1670
IL W+ + +C+ + C PP+ N V Y+C G
Sbjct: 1046 ----ILSGNTAHWSTKPPICQRI--PCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGS 1099
Query: 1671 ----------------------YGIGAVCSPLCVIP-------PSDPVMLPENITA---- 1697
GI + +P C+IP + +++ +N +
Sbjct: 1100 RGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 1159
Query: 1698 DTLEHWMEPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+ +E +P V + + C +W P+ L C + C+P
Sbjct: 1160 EVVEFRCQPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 1199
Score = 51.2 bits (121), Expect = 9e-06
Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 55/247 (22%)
Query: 1466 VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQG-LSPWLTCLEDGLWSLPEVYCKLE 1524
+ D + + N+SC+ G + + S C+ L G + W T P + ++
Sbjct: 568 ITDIQVGSRINYSCTTGHRLIGHSSAECI----LSGNAAHWST--------KPPICQRIP 615
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLL---KIQCLE 1581
C PP I N + + + ++N G++ Y C PG + G+ +L+ I C
Sbjct: 616 CGLPPTIANGDFISTN--RENFHYGSVVTYRCNPG------SGGRKVFELVGEPSIYCTS 667
Query: 1582 G----GIWEQGS---CIPVVCEPPPPVFEGMYECTNG--FSLDSQCVLNCNQE---REKL 1629
GIW + IP C PP V G+ N FSL+ C +
Sbjct: 668 NDDQVGIWSGPAPQCIIPNKCTPPN-VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPR 726
Query: 1630 PILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQGYGIG 1674
+ C W E C + C PPP L++ V Y CE GY +
Sbjct: 727 RVKCQALNKWEPELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLR 783
Query: 1675 AVCSPLC 1681
S C
Sbjct: 784 GAASMRC 790
Score = 51.2 bits (121), Expect = 9e-06
Identities = 48/186 (25%), Positives = 67/186 (36%), Gaps = 39/186 (20%)
Query: 1493 CVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTIC 1552
C P + G S + C +G W +C C PP IL+ L H QDN G
Sbjct: 1619 CQPGFVMVG-SHTVQCQTNGRWGPKLPHCSRVCQPPPEILHGEHTLSH--QDNFSPGQEV 1675
Query: 1553 KYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCE------PPPPVF-- 1602
Y C+P Y + +A + C G W E C C+ P V
Sbjct: 1676 FYSCEPSYDLRGAA---------SLHCTPQGDWSPEAPRCTVKSCDDFLGQLPHGRVLLP 1726
Query: 1603 -------EGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPP 1655
+ + C GF L + +C +L + LW +CE + CP
Sbjct: 1727 LNLQLGAKVSFVCDEGFRLKGRSASHC--------VLAGMKALWNSSVPVCEQI--FCPN 1776
Query: 1656 PPSELN 1661
PP+ LN
Sbjct: 1777 PPAILN 1782
Score = 50.8 bits (120), Expect = 1e-05
Identities = 59/235 (25%), Positives = 87/235 (37%), Gaps = 47/235 (20%)
Query: 1481 EGTKFLKRCSISCVPPAKLQGLSPWLTCLEDG---LWSLPEVYC-KLECDAPPIILNANL 1536
+G +F + SC +L G S TC+ G +W C ++ C PP I N +
Sbjct: 119 KGIQFGSQIKYSCTKGYRLIGSSS-ATCIISGDTVIWDNETPICDRIPCGLPPTITNGDF 177
Query: 1537 LLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLL---KIQCLEG----GIWEQGS 1589
+ + ++N G++ Y C PG + G+ +L+ I C GIW +
Sbjct: 178 ISTN--RENFHYGSVVTYRCNPG------SGGRKVFELVGEPSIYCTSNDDQVGIWSGPA 229
Query: 1590 ---CIPVVCEPPPPVFEGMYECTNG--FSLDSQCVLNCNQE---REKLPILCTKEGLWTQ 1641
IP C PP V G+ N FSL+ C + + C W
Sbjct: 230 PQCIIPNKCTPPN-VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQALNKWEP 288
Query: 1642 EFKLCENLQGECPPPPSELNS---------------VEYKCEQGYGIGAVCSPLC 1681
E C + C PPP L++ V Y CE GY + S C
Sbjct: 289 ELPSCSRV---CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC 340
Score = 48.5 bits (114), Expect = 6e-05
Identities = 59/275 (21%), Positives = 96/275 (34%), Gaps = 80/275 (29%)
Query: 1524 ECDAPPIILNANLLLPHCLQDNHD--VGTICKYECKPGYYVAESAEGKVRNKLLKIQCLE 1581
+C+AP + A P L D + +GT YEC+PGY + I CL+
Sbjct: 42 QCNAPEWLPFAR---PTNLTDEFEFPIGTYLNYECRPGY----------SGRPFSIICLK 88
Query: 1582 GGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKL---PILCTKE 1636
+W + C C PP GM G SQ +C + + C
Sbjct: 89 NSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIIS 148
Query: 1637 G---LWTQEFKLCENLQGECPPPPSELNS---------------VEYKCEQG-------- 1670
G +W E +C+ + C PP+ N V Y+C G
Sbjct: 149 GDTVIWDNETPICDRI--PCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFE 206
Query: 1671 ---------------YGIGAVCSPLCVIP-------PSDPVMLPENITA----DTLEHWM 1704
GI + +P C+IP + +++ +N + + +E
Sbjct: 207 LVGEPSIYCTSNDDQVGIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLNEVVEFRC 266
Query: 1705 EPVKV----QSIVCTGRRQWHPDPVLVHCIQSCEP 1735
+P V + + C +W P+ L C + C+P
Sbjct: 267 QPGFVMKGPRRVKCQALNKWEPE--LPSCSRVCQP 299
Score = 46.6 bits (109), Expect = 2e-04
Identities = 62/233 (26%), Positives = 80/233 (34%), Gaps = 58/233 (24%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 1152 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 1200
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--E 1586
P IL+ H QDN G Y C+PGY + +A + C G W E
Sbjct: 1201 PEILHGEHTPSH--QDNFSPGQEVFYSCEPGYDLRGAA---------SLHCTPQGDWSPE 1249
Query: 1587 QGSCIPVVCE------PPPPVF---------EGMYECTNGFSLDSQCVLNCNQEREKLPI 1631
C C+ P V + + C GF L V +C +
Sbjct: 1250 APRCAVKSCDDFLGQLPHGRVLFPLNLQLGAKVSFVCDEGFRLKGSSVSHC--------V 1301
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQG---YG--IGAVCSP 1679
L LW +CE++ CP PP+ LN G YG I C P
Sbjct: 1302 LVGMRSLWNNSVPVCEHI--FCPNPPAILNGRHTGTPSGDIPYGKEISYTCDP 1352
Score = 38.5 bits (88), Expect = 0.059
Identities = 51/206 (24%), Positives = 70/206 (33%), Gaps = 53/206 (25%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 252 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 300
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG 1588
P +L+A +DN G Y C+PGY + +A ++C G W
Sbjct: 301 PDVLHAERTQRD--KDNFSPGQEVFYSCEPGYDLRGAA---------SMRCTPQGDWSPA 349
Query: 1589 --SCIPVVCEP------------PPPVFEGM---YECTNGFSLDSQCVLNCNQEREKLPI 1631
+C C+ P + G + C GF L C +
Sbjct: 350 APTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC--------V 401
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPP 1657
L E LW +CE + CP PP
Sbjct: 402 LAGMESLWNSSVPVCEQI--FCPSPP 425
Score = 38.5 bits (88), Expect = 0.059
Identities = 51/206 (24%), Positives = 70/206 (33%), Gaps = 53/206 (25%)
Query: 1473 NYANFSCSEGTKFLKRCSISCVPPA----KLQGLSPWLTCLEDGLWSLPEVYCKLECDAP 1528
N + FS +E +F RC V K Q L+ W LP C C P
Sbjct: 702 NRSLFSLNEVVEF--RCQPGFVMKGPRRVKCQALNKWEP-------ELPS--CSRVCQPP 750
Query: 1529 PIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG 1588
P +L+A +DN G Y C+PGY + +A ++C G W
Sbjct: 751 PDVLHAERTQRD--KDNFSPGQEVFYSCEPGYDLRGAA---------SMRCTPQGDWSPA 799
Query: 1589 --SCIPVVCEP------------PPPVFEGM---YECTNGFSLDSQCVLNCNQEREKLPI 1631
+C C+ P + G + C GF L C +
Sbjct: 800 APTCEVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC--------V 851
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPP 1657
L E LW +CE + CP PP
Sbjct: 852 LAGMESLWNSSVPVCEQI--FCPSPP 875
Score = 31.2 bits (69), Expect = 9.5
Identities = 53/233 (22%), Positives = 77/233 (33%), Gaps = 63/233 (27%)
Query: 1476 NFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNA 1534
+F C EG + R + CV L G+ LW+ C+ + C PP ILN
Sbjct: 1736 SFVCDEGFRLKGRSASHCV----LAGMK--------ALWNSSVPVCEQIFCPNPPAILNG 1783
Query: 1535 NLLLPHCLQDNHDV--GTICKYECKPGYYVAESAEGKVRNKL--LKIQCLE----GGIWE 1586
H D+ G Y C G N + I+C G+W
Sbjct: 1784 R----HTGTPFGDIPYGKEISYACD-----THPDRGMTFNLIGESSIRCTSDPQGNGVWS 1834
Query: 1587 QGS-----CIPVVCEPPPPVFEGMY----------ECTNGFSLDSQCVLNCNQEREKLPI 1631
+ +P C PP + G Y T + D +L K I
Sbjct: 1835 SPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICDPGYLLV-----GKGFI 1889
Query: 1632 LCTKEGLWTQEFKLCENLQGECPPPPSELNS-------------VEYKCEQGY 1671
CT +G+W+Q C+ + P + ++ V KCE GY
Sbjct: 1890 FCTDQGIWSQLDHYCKEVNCSFPLFMNGISKELEMKKVYHYGDYVTLKCEDGY 1942
>gi|187960042 selectin E precursor [Homo sapiens]
Length = 610
Score = 70.9 bits (172), Expect = 1e-11
Identities = 68/280 (24%), Positives = 110/280 (39%), Gaps = 44/280 (15%)
Query: 1419 CAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWD-QNVSCLPVDCGV---PDPSLVNY 1474
C C+ GF L M + L SSG+WD + +C V C P V
Sbjct: 268 CTFDCEEGFEL----------MGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRC 317
Query: 1475 ANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILN 1533
++ E T F C+ +C LQG + + C G W+ C+ +C A + N
Sbjct: 318 SHSPAGEFT-FKSSCNFTCEEGFMLQGPAQ-VECTTQGQWTQQIPVCEAFQCTA---LSN 372
Query: 1534 ANLLLPHCLQD---NHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQG 1588
+CL + G+ C++ C+ G+ + S ++QC G W E+
Sbjct: 373 PERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSK---------RLQCGPTGEWDNEKP 423
Query: 1589 SCIPVVCEPPPPVFEGMYECTNG----FSLDSQCVLNCNQERE---KLPILCTKEGLWTQ 1641
+C V C+ +G+ C + F+ S C +C + E + CT +G WT+
Sbjct: 424 TCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTE 483
Query: 1642 EFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSPLC 1681
E C+ ++ P ++N C G VC C
Sbjct: 484 EVPSCQVVKCSSLAVPGKIN---MSCSGEPVFGTVCKFAC 520
Score = 65.1 bits (157), Expect = 6e-10
Identities = 55/210 (26%), Positives = 82/210 (39%), Gaps = 40/210 (19%)
Query: 1489 CSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCLQD--N 1545
CSISC L + C+ G WS P C + ECDA + N C Q+ +
Sbjct: 206 CSISC-DRGYLPSSMETMQCMSSGEWSAPIPACNVVECDA---VTNPANGFVECFQNPGS 261
Query: 1546 HDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPPVFE 1603
T C ++C+ G+ + + +QC G W E+ +C V C
Sbjct: 262 FPWNTTCTFDCEEGFELMGAQS---------LQCTSSGNWDNEKPTCKAVTCRAVRQPQN 312
Query: 1604 GMYECTNG----FSLDSQCVLNCNQE---REKLPILCTKEGLWTQEFKLCENLQ------ 1650
G C++ F+ S C C + + + CT +G WTQ+ +CE Q
Sbjct: 313 GSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSN 372
Query: 1651 -----GECPPPPSEL----NSVEYKCEQGY 1671
C P S +S E+ CEQG+
Sbjct: 373 PERGYMNCLPSASGSFRYGSSCEFSCEQGF 402
Score = 50.4 bits (119), Expect = 2e-05
Identities = 49/195 (25%), Positives = 75/195 (38%), Gaps = 25/195 (12%)
Query: 1381 QGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMK----CAITCQRGFALQASSGQY 1436
QGQ P + C +L +NC G + C +C++GF L+ S
Sbjct: 352 QGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQ 411
Query: 1437 IRPMQKEILLTCSSGHWD-QNVSCLPVDCGV---PDPSLVNYANFSCSEGTKFLKRCSIS 1492
P +G WD + +C V C P LV A+ E T + C+ S
Sbjct: 412 CGP----------TGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFT-YKSSCAFS 460
Query: 1493 CVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCLQDNHDVGTI 1551
C +L G S L C G W+ C++ +C + + N+ GT+
Sbjct: 461 CEEGFELHG-STQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINM----SCSGEPVFGTV 515
Query: 1552 CKYECKPGYYVAESA 1566
CK+ C G+ + SA
Sbjct: 516 CKFACPEGWTLNGSA 530
>gi|62739186 complement factor H isoform a precursor [Homo sapiens]
Length = 1231
Score = 69.7 bits (169), Expect = 2e-11
Identities = 64/290 (22%), Positives = 111/290 (38%), Gaps = 33/290 (11%)
Query: 1364 GLSAPSNCISEDEGQNHQGQSCIHRPCGKQDSCPSLLLDHADVVNCTSIGPGLMKCAITC 1423
G S NC H+ +CIH + C ++ + C S +++ +
Sbjct: 712 GDSVEFNCSESFTMIGHRSITCIHGVWTQLPQCVAI----DKLKKCKSSNLIILEEHLKN 767
Query: 1424 QRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSC--LPVDCGVPDPSLVNYANFSCSE 1481
++ F ++ R + I C +G WD V+C + P P + N N + +
Sbjct: 768 KKEFDHNSNIRYRCRGKEGWIHTVCINGRWDPEVNCSMAQIQLCPPPPQIPNSHNMTTTL 827
Query: 1482 GTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLW-SLPEVYCKLECDAPPIILNANLLLPH 1540
+ ++ S+ C +Q +TC +DG W S+P K+ C PP I + +
Sbjct: 828 NYRDGEKVSVLCQENYLIQE-GEEITC-KDGRWQSIPLCVEKIPCSQPPQIEHGTINSSR 885
Query: 1541 CLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPP 1600
Q+++ GT Y C+ G+ ++E E C G C + C+ PP
Sbjct: 886 SSQESYAHGTKLSYTCEGGFRISEENE---------TTCYMGKWSSPPQCEGLPCKSPPE 936
Query: 1601 VFEGM---------------YECTNGFSLDSQCVLNCNQEREKLPILCTK 1635
+ G+ Y+C GF +D + C E+ P C K
Sbjct: 937 ISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCLGEKWSHPPSCIK 986
Score = 43.1 bits (100), Expect = 0.002
Identities = 59/275 (21%), Positives = 99/275 (36%), Gaps = 49/275 (17%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANF 1477
K + TC+ GF + +E TC G W C + C P P + +
Sbjct: 896 KLSYTCEGGFRIS-----------EENETTCYMGKWSSPPQCEGLPCKSP-PEISHGVVA 943
Query: 1478 SCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLL 1537
S+ ++ + + C + G P + WS P K +C + P NA +
Sbjct: 944 HMSDSYQYGEEVTYKCFEGFGIDG--PAIAKCLGEKWSHPPSCIKTDCLSLPSFENAIPM 1001
Query: 1538 LPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEP 1597
+D + G Y C YY + A + C+ + +C C
Sbjct: 1002 GEK--KDVYKAGEQVTYTCAT-YYKMDGASN--------VTCINSRWTGRPTCRDTSCVN 1050
Query: 1598 PPPVFEG------MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQG 1651
PP V M + +G + QC ++ ++C G WT+ + C++ G
Sbjct: 1051 PPTVQNAYIVSRQMSKYPSGERVRYQCRSPYEMFGDE-EVMCLN-GNWTEPPQ-CKDSTG 1107
Query: 1652 ECPPPP---------------SELNSVEYKCEQGY 1671
+C PPP + +SVEY+C+ Y
Sbjct: 1108 KCGPPPPIDNGDITSFPLSVYAPASSVEYQCQNLY 1142
Score = 42.4 bits (98), Expect = 0.004
Identities = 45/200 (22%), Positives = 75/200 (37%), Gaps = 39/200 (19%)
Query: 1506 LTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAES 1565
+ C +G LP Y + EC+ P I ++ L+P +D + VG + K+ CKPG+ +
Sbjct: 551 IVCGYNGWSDLPICY-ERECELPKIDVH---LVPDRKKDQYKVGEVLKFSCKPGFTIVGP 606
Query: 1566 AEGKVRNKLLKIQCLEGGIWEQGSCIPVV------CEPPPPVFEG--------------- 1604
+QC G+ +P+ C PPP + G
Sbjct: 607 N---------SVQCYHFGL---SPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEV 654
Query: 1605 -MYECTNGFSLDSQCVLNC-NQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS 1662
Y C F + + C + E LP+ +E +L PP +S
Sbjct: 655 VEYYCNPRFLMKGPNKIQCVDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPYYYGDS 714
Query: 1663 VEYKCEQGYGIGAVCSPLCV 1682
VE+ C + + + S C+
Sbjct: 715 VEFNCSESFTMIGHRSITCI 734
Score = 42.4 bits (98), Expect = 0.004
Identities = 63/283 (22%), Positives = 93/283 (32%), Gaps = 85/283 (30%)
Query: 1446 LTCSSGHWDQNVSCLPVD----CG-----VPDPSLVNYANFSCSEGTKFLKRCSISCVPP 1496
+TC G W Q C+ +D C + + L N F + ++ RC
Sbjct: 731 ITCIHGVWTQLPQCVAIDKLKKCKSSNLIILEEHLKNKKEFDHNSNIRY--RC------- 781
Query: 1497 AKLQGLSPWL-TCLEDGLWSLPEVYCKLE----CDAPPIILNA-NLLLPHCLQDNHDVGT 1550
+G W+ T +G W PEV C + C PP I N+ N+ +D V
Sbjct: 782 ---RGKEGWIHTVCINGRWD-PEVNCSMAQIQLCPPPPQIPNSHNMTTTLNYRDGEKVSV 837
Query: 1551 ICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVV-CEPPPPVFEGM---- 1605
+C+ Y + E E I C +G C+ + C PP + G
Sbjct: 838 LCQ----ENYLIQEGEE---------ITCKDGRWQSIPLCVEKIPCSQPPQIEHGTINSS 884
Query: 1606 --------------YECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQG 1651
Y C GF + + C G W+ + CE L
Sbjct: 885 RSSQESYAHGTKLSYTCEGGFRISEENETTCYM------------GKWSSPPQ-CEGLPC 931
Query: 1652 ECPPPPSEL------------NSVEYKCEQGYGIGAVCSPLCV 1682
+ PP S V YKC +G+GI C+
Sbjct: 932 KSPPEISHGVVAHMSDSYQYGEEVTYKCFEGFGIDGPAIAKCL 974
Score = 39.3 bits (90), Expect = 0.035
Identities = 54/253 (21%), Positives = 85/253 (33%), Gaps = 55/253 (21%)
Query: 1383 QSCIHRPCGKQDSCP--SLLLDHADVVNCTSIGPGLMKCAITCQRGFALQASSGQYIRPM 1440
+ C RPCG P + L +V +K TC G+ L
Sbjct: 78 RKCQKRPCGHPGDTPFGTFTLTGGNVFEYG------VKAVYTCNEGYQLLGEINYR---- 127
Query: 1441 QKEILLTCSSGHWDQN------VSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCV 1494
C + W + V CLPV P+ + + F + C
Sbjct: 128 ------ECDTDGWTNDIPICEVVKCLPVTA--PENGKIVSSAMEPDREYHFGQAVRFVCN 179
Query: 1495 PPAKLQGLSPWLTCLEDGLWSLPEVYC-KLECDAPPIILNANLLLPHCLQDNHDVGTICK 1553
K++G + C +DG WS + C ++ C +P +I + + ++N +
Sbjct: 180 SGYKIEG-DEEMHCSDDGFWSKEKPKCVEISCKSPDVINGSPISQKIIYKENERF----Q 234
Query: 1554 YECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPP-------PPV----- 1601
Y+C GY +E + C E G SC C+ P P+
Sbjct: 235 YKCNMGYEYSERGDA---------VCTESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHR 285
Query: 1602 --FEGMYECTNGF 1612
E Y+C NGF
Sbjct: 286 TGDEITYQCRNGF 298
Score = 38.9 bits (89), Expect = 0.045
Identities = 56/242 (23%), Positives = 89/242 (36%), Gaps = 26/242 (10%)
Query: 1448 CSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFL--KRCSISCVPPAKLQGLSPW 1505
C+ W V CL C P L N ++ + G KF+ K ++C P L
Sbjct: 374 CTQDGWSPAVPCLR-KCYFP--YLEN--GYNQNHGRKFVQGKSIDVACHPGYALPKAQTT 428
Query: 1506 LTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAES 1565
+TC+E+G P C I + + Q + + KY+CK GY A+
Sbjct: 429 VTCMENGWSPTPRCIRVKTCSKSSIDIENGFISES--QYTYALKEKAKYQCKLGYVTADG 486
Query: 1566 AEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQE 1625
I C + G Q +CI C+ P + F L+ C+
Sbjct: 487 ETSG------SITCGKDGWSAQPTCIK-SCDIPVFMNARTKNDFTWFKLNDTLDYECHDG 539
Query: 1626 REKL------PILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCEQGYGIGAVCSP 1679
E I+C G W+ + +C + EC P +++ V + + Y +G V
Sbjct: 540 YESNTGSTTGSIVCGYNG-WS-DLPIC--YERECELPKIDVHLVPDRKKDQYKVGEVLKF 595
Query: 1680 LC 1681
C
Sbjct: 596 SC 597
Score = 36.6 bits (83), Expect = 0.23
Identities = 69/287 (24%), Positives = 98/287 (34%), Gaps = 40/287 (13%)
Query: 1458 SCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKL-QGLSPWLTCLEDGLWSL 1516
SC P + P+ V +F S K SC PP +L G T E G +
Sbjct: 596 SCKP-GFTIVGPNSVQCYHFGLSPDLPICKEQVQSCGPPPELLNGNVKEKTKEEYGHSEV 654
Query: 1517 PEVYC----------KLECDAPPIILNANLLLPHCLQDNHDVGTICKYE------CKPGY 1560
E YC K++C + LP C+ + G I + E P Y
Sbjct: 655 VEYYCNPRFLMKGPNKIQC-----VDGEWTTLPVCIVEESTCGDIPELEHGWAQLSSPPY 709
Query: 1561 YVAESAEGKVRNKLL-----KIQCLEGGIWEQ-GSCIPV----VCEPPPPVF-EGMYECT 1609
Y +S E I C+ G +W Q C+ + C+ + E +
Sbjct: 710 YYGDSVEFNCSESFTMIGHRSITCIHG-VWTQLPQCVAIDKLKKCKSSNLIILEEHLKNK 768
Query: 1610 NGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGE-CPPPPSELNSVEYKCE 1668
F +S C + + +C G W E C Q + CPPPP NS
Sbjct: 769 KEFDHNSNIRYRCRGKEGWIHTVCIN-GRWDPEVN-CSMAQIQLCPPPPQIPNSHNMTTT 826
Query: 1669 QGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQSIVCT 1715
Y G S LC + + E IT P+ V+ I C+
Sbjct: 827 LNYRDGEKVSVLC--QENYLIQEGEEITCKDGRWQSIPLCVEKIPCS 871
Score = 33.5 bits (75), Expect = 1.9
Identities = 38/164 (23%), Positives = 55/164 (33%), Gaps = 39/164 (23%)
Query: 1497 AKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYEC 1556
AK+ L W C+ + +C+ P N +L + GT Y+C
Sbjct: 5 AKIICLMLWAICVAE------------DCNELPPRRNTEILTGSWSDQTYPEGTQAIYKC 52
Query: 1557 KPGY-------YVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECT 1609
+PGY V E N L K C C P G + T
Sbjct: 53 RPGYRSLGNVIMVCRKGEWVALNPLRK-------------CQKRPCGHPGDTPFGTFTLT 99
Query: 1610 NG--FSLDSQCVLNCNQEREKLPIL----CTKEGLWTQEFKLCE 1647
G F + V CN+ + L + C +G WT + +CE
Sbjct: 100 GGNVFEYGVKAVYTCNEGYQLLGEINYRECDTDG-WTNDIPICE 142
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 58.5 bits (140), Expect = 6e-08
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 1492 SCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTI 1551
+C+ L+G S + C G W C+ EC APP ILN H ++ D GT
Sbjct: 378 ACMFGFTLKG-SKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVR--FDPGTS 434
Query: 1552 CKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVCE--------PPPPV 1601
KY C PGY + IQC G+W C CE P
Sbjct: 435 IKYSCNPGYVLVGEE---------SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
Query: 1602 F---EGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPP 1657
F + C G+ L C + +P W E +LC+ + CPPPP
Sbjct: 486 FVRPDVNSSCGEGYKLSGSVYQEC---QGTIP--------WFMEIRLCKEI--TCPPPP 531
Score = 47.0 bits (110), Expect = 2e-04
Identities = 84/368 (22%), Positives = 131/368 (35%), Gaps = 97/368 (26%)
Query: 1353 SAVALRTSSRIGLSA-----PSNCISEDEGQNHQGQSCIHRPCGKQDSCPSLLLDHADVV 1407
S L+ SS+I A P + E E H QS P G + ++V
Sbjct: 632 SGFTLKGSSQIRCKADNTWDPEIPVCEKETCQHVRQSLQELPAGSR----------VELV 681
Query: 1408 NCTSIGPGLMKCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGV 1466
N + CQ G+ L + Q + + +G W + + C + C
Sbjct: 682 NTS------------CQDGYQLTGHAYQMCQDAE--------NGIWFKKIPLCKVIHCH- 720
Query: 1467 PDPSLVN------------YAN---FSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLED 1511
P P +VN Y N + C +G L + C +K
Sbjct: 721 PPPVIVNGKHTGMMAENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK-----------GH 769
Query: 1512 GLWSLPEVYCK-----LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESA 1566
G WS P C C P + L H ++D+ + +C PG+
Sbjct: 770 GSWSGPSPQCLRSPPVTRCPNPEVKHGYKLNKTHSAYSHNDIVYV---DCNPGF------ 820
Query: 1567 EGKVRNKLLKIQCLEGGIWEQG--SCIP---VVCEPPPPVFEGMYECTN--GFSLDSQCV 1619
+ N I+C W G +CI + C PPP G + N FS +
Sbjct: 821 ---IMNGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSIL 877
Query: 1620 LNCNQER----EKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCE--QGYGI 1673
+C+Q E L +LCT EG W+Q C+ + C P++++ ++ E + Y
Sbjct: 878 YSCDQGYLLVGEAL-LLCTHEGTWSQPAPHCKEV--NC-SSPADMDGIQKGLEPRKMYQY 933
Query: 1674 GAVCSPLC 1681
GAV + C
Sbjct: 934 GAVVTLEC 941
Score = 31.6 bits (70), Expect = 7.2
Identities = 50/262 (19%), Positives = 85/262 (32%), Gaps = 60/262 (22%)
Query: 1460 LPVDCGVPDPSL---VNYAN----------FSCSEGTKFLKRCSISCVPPAKLQGLSPWL 1506
L + CG P P L ++Y + +SCS + + S+ C+ K+
Sbjct: 19 LGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKV------- 71
Query: 1507 TCLEDGLWSLPEVYCKL---ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVA 1563
DG W P C+ P I+ + H G + CK + +
Sbjct: 72 ----DGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRH--GDSVTFACKTNFSM- 124
Query: 1564 ESAEGKVRNKLLKIQCLEGGIWEQG------SCIPVVCEPPPPVFEG------------- 1604
N + C +W S P+ C P + G
Sbjct: 125 --------NGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPG 176
Query: 1605 ---MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN 1661
Y C +G+ L + ++NC + + T E + N + + PP
Sbjct: 177 LSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV 236
Query: 1662 SVEYKCEQGYGIGAVCSPLCVI 1683
+ + C++GY + S CVI
Sbjct: 237 TANFFCDEGYRLQGPPSSRCVI 258
Score = 31.6 bits (70), Expect = 7.2
Identities = 37/170 (21%), Positives = 57/170 (33%), Gaps = 29/170 (17%)
Query: 1506 LTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAE 1564
+ CL G WS C+ C + N + P L+ VG + C GY +
Sbjct: 195 INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILR----VGVTANFFCDEGYRLQG 250
Query: 1565 SAEGKVRNKLLKIQCLEGGIW-EQGSCIPVVCEPPPPVFEGMY--ECTNGFSLDSQCVLN 1621
+ + +G W + C + C PPP+ G + S S
Sbjct: 251 PPSSRC------VIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYT 304
Query: 1622 CNQERE---------KLPILCT----KEGLWTQEFKLCE--NLQGECPPP 1656
C+ + E + + CT K G W+ CE +CP P
Sbjct: 305 CDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 58.5 bits (140), Expect = 6e-08
Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 1492 SCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTI 1551
+C+ L+G S + C G W C+ EC APP ILN H ++ D GT
Sbjct: 378 ACMFGFTLKG-SKQIRCNAQGTWEPSAPVCEKECQAPPNILNGQKEDRHMVR--FDPGTS 434
Query: 1552 CKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVCE--------PPPPV 1601
KY C PGY + IQC G+W C CE P
Sbjct: 435 IKYSCNPGYVLVGEE---------SIQCTSEGVWTPPVPQCKVAACEATGRQLLTKPQHQ 485
Query: 1602 F---EGMYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPP 1657
F + C G+ L C + +P W E +LC+ + CPPPP
Sbjct: 486 FVRPDVNSSCGEGYKLSGSVYQEC---QGTIP--------WFMEIRLCKEI--TCPPPP 531
Score = 46.6 bits (109), Expect = 2e-04
Identities = 68/294 (23%), Positives = 109/294 (37%), Gaps = 70/294 (23%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVN------- 1473
+CQ G+ L + Q + + +G W + + C + C P P +VN
Sbjct: 743 SCQDGYQLTGHAYQMCQDAE--------NGIWFKKIPLCKVIHCH-PPPVIVNGKHTGMM 793
Query: 1474 -----YAN---FSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK--- 1522
Y N + C +G L + C +K G WS P C
Sbjct: 794 AENFLYGNEVSYECDQGFYLLGEKKLQCRSDSK-----------GHGSWSGPSPQCLRSP 842
Query: 1523 --LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCL 1580
C P + L H ++D+ + +C PG+ + N I+C
Sbjct: 843 PVTRCPNPEVKHGYKLNKTHSAYSHNDIVYV---DCNPGF---------IMNGSRVIRCH 890
Query: 1581 EGGIWEQG--SCIP---VVCEPPPPVFEGMYECTN--GFSLDSQCVLNCNQER----EKL 1629
W G +CI + C PPP G + N FS + +C+Q E L
Sbjct: 891 TDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEAL 950
Query: 1630 PILCTKEGLWTQEFKLCENLQGECPPPPSELNSVEYKCE--QGYGIGAVCSPLC 1681
+LCT EG W+Q C+ + C P++++ ++ E + Y GAV + C
Sbjct: 951 -LLCTHEGTWSQPAPHCKEV--NC-SSPADMDGIQKGLEPRKMYQYGAVVTLEC 1000
Score = 31.6 bits (70), Expect = 7.2
Identities = 50/262 (19%), Positives = 85/262 (32%), Gaps = 60/262 (22%)
Query: 1460 LPVDCGVPDPSL---VNYAN----------FSCSEGTKFLKRCSISCVPPAKLQGLSPWL 1506
L + CG P P L ++Y + +SCS + + S+ C+ K+
Sbjct: 19 LGISCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKV------- 71
Query: 1507 TCLEDGLWSLPEVYCKL---ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVA 1563
DG W P C+ P I+ + H G + CK + +
Sbjct: 72 ----DGTWDKPAPKCEYFNKYSSCPEPIVPGGYKIRGSTPYRH--GDSVTFACKTNFSM- 124
Query: 1564 ESAEGKVRNKLLKIQCLEGGIWEQG------SCIPVVCEPPPPVFEG------------- 1604
N + C +W S P+ C P + G
Sbjct: 125 --------NGNKSVWCQANNMWGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAPG 176
Query: 1605 ---MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN 1661
Y C +G+ L + ++NC + + T E + N + + PP
Sbjct: 177 LSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILRVGV 236
Query: 1662 SVEYKCEQGYGIGAVCSPLCVI 1683
+ + C++GY + S CVI
Sbjct: 237 TANFFCDEGYRLQGPPSSRCVI 258
Score = 31.6 bits (70), Expect = 7.2
Identities = 37/170 (21%), Positives = 57/170 (33%), Gaps = 29/170 (17%)
Query: 1506 LTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAE 1564
+ CL G WS C+ C + N + P L+ VG + C GY +
Sbjct: 195 INCLSSGKWSAVPPTCEEARCKSLGRFPNGKVKEPPILR----VGVTANFFCDEGYRLQG 250
Query: 1565 SAEGKVRNKLLKIQCLEGGIW-EQGSCIPVVCEPPPPVFEGMY--ECTNGFSLDSQCVLN 1621
+ + +G W + C + C PPP+ G + S S
Sbjct: 251 PPSSRC------VIAGQGVAWTKMPVCEEIFCPSPPPILNGRHIGNSLANVSYGSIVTYT 304
Query: 1622 CNQERE---------KLPILCT----KEGLWTQEFKLCE--NLQGECPPP 1656
C+ + E + + CT K G W+ CE +CP P
Sbjct: 305 CDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELSTSAVQCPHP 354
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 54.3 bits (129), Expect = 1e-06
Identities = 69/276 (25%), Positives = 99/276 (35%), Gaps = 59/276 (21%)
Query: 1423 CQRGFALQASSGQYIRPMQKEILLTCSSGH-WD-QNVSCLPVDCGVPDPSLVNYANFSCS 1480
C GF L SS + C H W Q SC+PV CG P + +
Sbjct: 2803 CNPGFRLIGSS-----------VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS---G 2848
Query: 1481 EGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANL--L 1537
G F + SC +QG + C + WS P CK+ C P I N+
Sbjct: 2849 NGFNFNDVVTFSCNIGYLMQGPTK-AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESK 2907
Query: 1538 LPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVC 1595
+ H N GT+ Y+C PGY++ S+ + C G W++ CI + C
Sbjct: 2908 IEH---GNFTYGTVVFYDCNPGYFLFGSS---------VLICQPNGQWDKPLPECIMIDC 2955
Query: 1596 ----EPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKL---PILCTKEGLWTQEFKLCE- 1647
PP V G ++ S +C +R L C G W+ C
Sbjct: 2956 GHPGVPPNAVLSG-----EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 3010
Query: 1648 NLQGECPPPPS------------ELNSVEYKCEQGY 1671
+ G C P + ++V Y C+ GY
Sbjct: 3011 DATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGY 3046
Score = 50.4 bits (119), Expect = 2e-05
Identities = 72/306 (23%), Positives = 108/306 (35%), Gaps = 59/306 (19%)
Query: 1450 SGHW---DQNVSCLPVDCG-VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPW 1505
+G W ++ C + CG +P P N S G+ + C + + L G S
Sbjct: 2702 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFM----LVG-SAV 2756
Query: 1506 LTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAE 1564
CL GLWS E C C P +I+N + + +N+ Y+C PG+ +
Sbjct: 2757 RECLSSGLWSESETRCLAGHCGIPELIVNGQV-----IGENYGYRDTVVYQCNPGFRLIG 2811
Query: 1565 SAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNC 1622
S+ ++I C + W + SC+PV C P G NGF+ + +C
Sbjct: 2812 SS--------VRI-CQQDHNWSGQLPSCVPVSCGHPGSPIYGR-TSGNGFNFNDVVTFSC 2861
Query: 1623 N---QEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS----------------V 1663
N + C W+ +C+ + C P NS V
Sbjct: 2862 NIGYLMQGPTKAQCQANRQWSHPPPMCKVV--NCSDPGIPANSKRESKIEHGNFTYGTVV 2919
Query: 1664 EYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQS-----------I 1712
Y C GY + +C LPE I D + P V S
Sbjct: 2920 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY 2979
Query: 1713 VCTGRR 1718
CTG+R
Sbjct: 2980 SCTGKR 2985
Score = 46.2 bits (108), Expect = 3e-04
Identities = 71/290 (24%), Positives = 111/290 (38%), Gaps = 64/290 (22%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNV-SCLPVDCGVPDPSLVNYANFSCS 1480
+C G+ L SG +R ++G W + +C + CG DP + AN
Sbjct: 3100 SCMEGYIL---SGPSVRQCT-------ANGTWSGTLPNCTIISCG--DPGIP--AN-GLR 3144
Query: 1481 EGTKFL--KRCSISCVP--PAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNAN 1535
G ++ + S C P +L G S TC +G WS C+ + C PP I N
Sbjct: 3145 YGDDYVVGQNVSYMCQPGYTMELNG-SRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGR 3203
Query: 1536 LLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPV 1593
L N D G Y C PGY ++ A + C+ G W E C+P
Sbjct: 3204 LE-----GTNFDWGFSISYICSPGYELSFPA---------VLTCVGNGTWSGEVPQCLPK 3249
Query: 1594 VCEPPPPVFEG-------MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLC 1646
C P +G +Y+ FS + +L + R +C +G W+ C
Sbjct: 3250 FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTR-----ICQADGTWSGSSPHC 3304
Query: 1647 -ENLQGECPPP-----PSELNS--------VEYKCEQGYGIGAVCSPLCV 1682
E Q C P S+ N+ V++ C++G+ + + C+
Sbjct: 3305 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL 3354
Score = 42.4 bits (98), Expect = 0.004
Identities = 62/261 (23%), Positives = 92/261 (35%), Gaps = 61/261 (23%)
Query: 1447 TCS-SGHW---------DQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPP 1496
TC +GHW D +C D G P +NF ++ +C
Sbjct: 2994 TCQLNGHWSGSQPHCSGDATGTC--GDPGTPGHGSRQESNFRTKSTVRY------ACDTG 3045
Query: 1497 AKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYE 1555
L G S TCL +G W+ + CK ++C P N + D + Y
Sbjct: 3046 YILHG-SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRI----DGTTFSSSVIYS 3100
Query: 1556 CKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGM-------- 1605
C GY ++ + VR QC G W +C + C P G+
Sbjct: 3101 CMEGYILSGPS---VR------QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVV 3151
Query: 1606 -----YECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSEL 1660
Y C G++++ LN ++ R CT G W+ C + CP PP
Sbjct: 3152 GQNVSYMCQPGYTME----LNGSRIRT-----CTINGTWSGVMPTCRAVT--CPTPPQIS 3200
Query: 1661 NS--VEYKCEQGYGIGAVCSP 1679
N + G+ I +CSP
Sbjct: 3201 NGRLEGTNFDWGFSISYICSP 3221
Score = 32.7 bits (73), Expect = 3.3
Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESA 1566
C PP + NA +L D ++G I +Y+C PG+ + +A
Sbjct: 2355 CQPPPPVPNAEILTE---DDEFEIGDIIRYQCLPGFTLVGNA 2393
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 54.3 bits (129), Expect = 1e-06
Identities = 69/276 (25%), Positives = 99/276 (35%), Gaps = 59/276 (21%)
Query: 1423 CQRGFALQASSGQYIRPMQKEILLTCSSGH-WD-QNVSCLPVDCGVPDPSLVNYANFSCS 1480
C GF L SS + C H W Q SC+PV CG P + +
Sbjct: 2674 CNPGFRLIGSS-----------VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS---G 2719
Query: 1481 EGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANL--L 1537
G F + SC +QG + C + WS P CK+ C P I N+
Sbjct: 2720 NGFNFNDVVTFSCNIGYLMQGPTK-AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESK 2778
Query: 1538 LPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVC 1595
+ H N GT+ Y+C PGY++ S+ + C G W++ CI + C
Sbjct: 2779 IEH---GNFTYGTVVFYDCNPGYFLFGSS---------VLICQPNGQWDKPLPECIMIDC 2826
Query: 1596 ----EPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKL---PILCTKEGLWTQEFKLCE- 1647
PP V G ++ S +C +R L C G W+ C
Sbjct: 2827 GHPGVPPNAVLSG-----EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 2881
Query: 1648 NLQGECPPPPS------------ELNSVEYKCEQGY 1671
+ G C P + ++V Y C+ GY
Sbjct: 2882 DATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGY 2917
Score = 53.1 bits (126), Expect = 2e-06
Identities = 73/307 (23%), Positives = 109/307 (35%), Gaps = 59/307 (19%)
Query: 1449 SSGHW---DQNVSCLPVDCG-VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSP 1504
S G W ++ C+ + CG +P P N S G+ + C + + L G S
Sbjct: 2572 SDGTWSNHNKTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFM----LVG-SA 2626
Query: 1505 WLTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVA 1563
CL GLWS E C C P +I+N + + +N+ Y+C PG+ +
Sbjct: 2627 VRECLSSGLWSESETRCLAGHCGIPELIVNGQV-----IGENYGYRDTVVYQCNPGFRLI 2681
Query: 1564 ESAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLN 1621
S+ ++I C + W + SC+PV C P G NGF+ + +
Sbjct: 2682 GSS--------VRI-CQQDHNWSGQLPSCVPVSCGHPGSPIYGR-TSGNGFNFNDVVTFS 2731
Query: 1622 CN---QEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS---------------- 1662
CN + C W+ +C+ + C P NS
Sbjct: 2732 CNIGYLMQGPTKAQCQANRQWSHPPPMCKVV--NCSDPGIPANSKRESKIEHGNFTYGTV 2789
Query: 1663 VEYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQS----------- 1711
V Y C GY + +C LPE I D + P V S
Sbjct: 2790 VFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVH 2849
Query: 1712 IVCTGRR 1718
CTG+R
Sbjct: 2850 YSCTGKR 2856
Score = 46.2 bits (108), Expect = 3e-04
Identities = 71/290 (24%), Positives = 111/290 (38%), Gaps = 64/290 (22%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNV-SCLPVDCGVPDPSLVNYANFSCS 1480
+C G+ L SG +R ++G W + +C + CG DP + AN
Sbjct: 2971 SCMEGYIL---SGPSVRQCT-------ANGTWSGTLPNCTIISCG--DPGIP--AN-GLR 3015
Query: 1481 EGTKFL--KRCSISCVP--PAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNAN 1535
G ++ + S C P +L G S TC +G WS C+ + C PP I N
Sbjct: 3016 YGDDYVVGQNVSYMCQPGYTMELNG-SRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGR 3074
Query: 1536 LLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPV 1593
L N D G Y C PGY ++ A + C+ G W E C+P
Sbjct: 3075 LE-----GTNFDWGFSISYICSPGYELSFPA---------VLTCVGNGTWSGEVPQCLPK 3120
Query: 1594 VCEPPPPVFEG-------MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLC 1646
C P +G +Y+ FS + +L + R +C +G W+ C
Sbjct: 3121 FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTR-----ICQADGTWSGSSPHC 3175
Query: 1647 -ENLQGECPPP-----PSELNS--------VEYKCEQGYGIGAVCSPLCV 1682
E Q C P S+ N+ V++ C++G+ + + C+
Sbjct: 3176 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL 3225
Score = 42.4 bits (98), Expect = 0.004
Identities = 62/261 (23%), Positives = 92/261 (35%), Gaps = 61/261 (23%)
Query: 1447 TCS-SGHW---------DQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPP 1496
TC +GHW D +C D G P +NF ++ +C
Sbjct: 2865 TCQLNGHWSGSQPHCSGDATGTC--GDPGTPGHGSRQESNFRTKSTVRY------ACDTG 2916
Query: 1497 AKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYE 1555
L G S TCL +G W+ + CK ++C P N + D + Y
Sbjct: 2917 YILHG-SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRI----DGTTFSSSVIYS 2971
Query: 1556 CKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGM-------- 1605
C GY ++ + VR QC G W +C + C P G+
Sbjct: 2972 CMEGYILSGPS---VR------QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVV 3022
Query: 1606 -----YECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSEL 1660
Y C G++++ LN ++ R CT G W+ C + CP PP
Sbjct: 3023 GQNVSYMCQPGYTME----LNGSRIRT-----CTINGTWSGVMPTCRAVT--CPTPPQIS 3071
Query: 1661 NS--VEYKCEQGYGIGAVCSP 1679
N + G+ I +CSP
Sbjct: 3072 NGRLEGTNFDWGFSISYICSP 3092
Score = 32.7 bits (73), Expect = 3.3
Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESA 1566
C PP + NA +L D ++G I +Y+C PG+ + +A
Sbjct: 2291 CQPPPPVPNAEILTE---DDEFEIGDIIRYQCLPGFTLVGNA 2329
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 54.3 bits (129), Expect = 1e-06
Identities = 69/276 (25%), Positives = 99/276 (35%), Gaps = 59/276 (21%)
Query: 1423 CQRGFALQASSGQYIRPMQKEILLTCSSGH-WD-QNVSCLPVDCGVPDPSLVNYANFSCS 1480
C GF L SS + C H W Q SC+PV CG P + +
Sbjct: 2843 CNPGFRLIGSS-----------VRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTS---G 2888
Query: 1481 EGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANL--L 1537
G F + SC +QG + C + WS P CK+ C P I N+
Sbjct: 2889 NGFNFNDVVTFSCNIGYLMQGPTK-AQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESK 2947
Query: 1538 LPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQ--GSCIPVVC 1595
+ H N GT+ Y+C PGY++ S+ + C G W++ CI + C
Sbjct: 2948 IEH---GNFTYGTVVFYDCNPGYFLFGSS---------VLICQPNGQWDKPLPECIMIDC 2995
Query: 1596 ----EPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKL---PILCTKEGLWTQEFKLCE- 1647
PP V G ++ S +C +R L C G W+ C
Sbjct: 2996 GHPGVPPNAVLSG-----EKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG 3050
Query: 1648 NLQGECPPPPS------------ELNSVEYKCEQGY 1671
+ G C P + ++V Y C+ GY
Sbjct: 3051 DATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGY 3086
Score = 50.4 bits (119), Expect = 2e-05
Identities = 72/306 (23%), Positives = 108/306 (35%), Gaps = 59/306 (19%)
Query: 1450 SGHW---DQNVSCLPVDCG-VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPW 1505
+G W ++ C + CG +P P N S G+ + C + + L G S
Sbjct: 2742 NGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFM----LVG-SAV 2796
Query: 1506 LTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAE 1564
CL GLWS E C C P +I+N + + +N+ Y+C PG+ +
Sbjct: 2797 RECLSSGLWSESETRCLAGHCGIPELIVNGQV-----IGENYGYRDTVVYQCNPGFRLIG 2851
Query: 1565 SAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNC 1622
S+ ++I C + W + SC+PV C P G NGF+ + +C
Sbjct: 2852 SS--------VRI-CQQDHNWSGQLPSCVPVSCGHPGSPIYGR-TSGNGFNFNDVVTFSC 2901
Query: 1623 N---QEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELNS----------------V 1663
N + C W+ +C+ + C P NS V
Sbjct: 2902 NIGYLMQGPTKAQCQANRQWSHPPPMCKVV--NCSDPGIPANSKRESKIEHGNFTYGTVV 2959
Query: 1664 EYKCEQGYGIGAVCSPLCVIPPSDPVMLPENITADTLEHWMEPVKVQS-----------I 1712
Y C GY + +C LPE I D + P V S
Sbjct: 2960 FYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHY 3019
Query: 1713 VCTGRR 1718
CTG+R
Sbjct: 3020 SCTGKR 3025
Score = 46.2 bits (108), Expect = 3e-04
Identities = 71/290 (24%), Positives = 111/290 (38%), Gaps = 64/290 (22%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNV-SCLPVDCGVPDPSLVNYANFSCS 1480
+C G+ L SG +R ++G W + +C + CG DP + AN
Sbjct: 3140 SCMEGYIL---SGPSVRQCT-------ANGTWSGTLPNCTIISCG--DPGIP--AN-GLR 3184
Query: 1481 EGTKFL--KRCSISCVP--PAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNAN 1535
G ++ + S C P +L G S TC +G WS C+ + C PP I N
Sbjct: 3185 YGDDYVVGQNVSYMCQPGYTMELNG-SRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGR 3243
Query: 1536 LLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPV 1593
L N D G Y C PGY ++ A + C+ G W E C+P
Sbjct: 3244 LE-----GTNFDWGFSISYICSPGYELSFPA---------VLTCVGNGTWSGEVPQCLPK 3289
Query: 1594 VCEPPPPVFEG-------MYECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLC 1646
C P +G +Y+ FS + +L + R +C +G W+ C
Sbjct: 3290 FCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTR-----ICQADGTWSGSSPHC 3344
Query: 1647 -ENLQGECPPP-----PSELNS--------VEYKCEQGYGIGAVCSPLCV 1682
E Q C P S+ N+ V++ C++G+ + + C+
Sbjct: 3345 IEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCL 3394
Score = 42.4 bits (98), Expect = 0.004
Identities = 62/261 (23%), Positives = 92/261 (35%), Gaps = 61/261 (23%)
Query: 1447 TCS-SGHW---------DQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPP 1496
TC +GHW D +C D G P +NF ++ +C
Sbjct: 3034 TCQLNGHWSGSQPHCSGDATGTC--GDPGTPGHGSRQESNFRTKSTVRY------ACDTG 3085
Query: 1497 AKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYE 1555
L G S TCL +G W+ + CK ++C P N + D + Y
Sbjct: 3086 YILHG-SEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRI----DGTTFSSSVIYS 3140
Query: 1556 CKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCEPPPPVFEGM-------- 1605
C GY ++ + VR QC G W +C + C P G+
Sbjct: 3141 CMEGYILSGPS---VR------QCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVV 3191
Query: 1606 -----YECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSEL 1660
Y C G++++ LN ++ R CT G W+ C + CP PP
Sbjct: 3192 GQNVSYMCQPGYTME----LNGSRIRT-----CTINGTWSGVMPTCRAVT--CPTPPQIS 3240
Query: 1661 NS--VEYKCEQGYGIGAVCSP 1679
N + G+ I +CSP
Sbjct: 3241 NGRLEGTNFDWGFSISYICSP 3261
Score = 32.7 bits (73), Expect = 3.3
Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESA 1566
C PP + NA +L D ++G I +Y+C PG+ + +A
Sbjct: 2395 CQPPPPVPNAEILTE---DDEFEIGDIIRYQCLPGFTLVGNA 2433
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 52.8 bits (125), Expect = 3e-06
Identities = 66/246 (26%), Positives = 90/246 (36%), Gaps = 46/246 (18%)
Query: 1451 GHWDQNVS-CLPVDCGV-PDPSLVNYA---NFSCSEGTKFLKRCSISCVPPAKLQGLSPW 1505
GHW ++ C GV DP + + S GT C V L+G S
Sbjct: 2818 GHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHV----LRGSSE- 2872
Query: 1506 LTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAE 1564
TC +G WS + C + C P NA ++ L + + YEC+ GYY
Sbjct: 2873 RTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSI----VYECREGYYATG 2928
Query: 1565 SAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDS----QC 1618
LL C G W C+ + C P G+ N F + QC
Sbjct: 2929 ---------LLSRHCSVNGTWTGSDPECLVINCGDPGIPANGL-RLGNDFRYNKTVTYQC 2978
Query: 1619 VLNCNQEREKLPIL-CTKEGLWTQEFKLCENLQGECPPPPSELN------------SVEY 1665
V E ++ +L CTK+ W +C+ L C PPP N SV Y
Sbjct: 2979 VPGYMMESHRVSVLSCTKDRTWNGTKPVCKALM--CKPPPLIPNGKVVGSDFMWGSSVTY 3036
Query: 1666 KCEQGY 1671
C +GY
Sbjct: 3037 ACLEGY 3042
Score = 47.8 bits (112), Expect = 1e-04
Identities = 70/299 (23%), Positives = 108/299 (36%), Gaps = 83/299 (27%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTC-SSGHW-DQNV--SCLPVDCGVPDPSLVN 1473
K +C G+ LQA + E C +G W ++NV C+PV C PD S ++
Sbjct: 2552 KAMYSCSEGYHLQAGA---------EATAECLDTGLWSNRNVPPQCVPVTC--PDVSSIS 2600
Query: 1474 YAN----FSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVY--CKL-ECD 1526
+ +F + + C P G + C +G WSL + C++ C
Sbjct: 2601 VEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRV-IRCQANGKWSLGDSTPTCRIISCG 2659
Query: 1527 APPIILNANLLLPHCLQDNHDVGTICKY------ECKPGYYVAESAEGKVRNKLLKIQCL 1580
PI N H +GT+ Y C GY + S +VR +C+
Sbjct: 2660 ELPIPPNG-----------HRIGTLSVYGATAIFSCNSGYTLVGS---RVR------ECM 2699
Query: 1581 EGGIWEQGS--CIPVVCEPPPPVFEG-------------MYECTNGFSLDSQCVLNCNQE 1625
G+W C+ C P P+ G +Y+C GF L V C Q+
Sbjct: 2700 ANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQD 2759
Query: 1626 REKLPILCTKEGLWTQEFKLCENLQGECP--PPPSELNSVEYKCEQGYGIGAVCSPLCV 1682
W+ + C + P PP S+++ Y +GAV C+
Sbjct: 2760 HH-----------WSGKTPFCVLVSCGHPGSPPHSQMSG------DSYTVGAVVRYSCI 2801
Score = 42.0 bits (97), Expect = 0.005
Identities = 65/300 (21%), Positives = 97/300 (32%), Gaps = 94/300 (31%)
Query: 1449 SSGHWD-QNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSI--SCVPPAKLQGLSPW 1505
++G W V CL CG P+P + + N G + R S+ C +L G+S
Sbjct: 2700 ANGLWSGSEVRCLAGHCGTPEPIVNGHIN-----GENYSYRGSVVYQCNAGFRLIGMSVR 2754
Query: 1506 LTCLEDGLWSLPEVYCKL-ECDAP---------------------------PIILNANLL 1537
+ C +D WS +C L C P ++ N+ +
Sbjct: 2755 I-CQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRM 2813
Query: 1538 ----------LPHC-------------------LQDNHDVGTICKYECKPGYYVAESAEG 1568
LPHC L D+ D GT+ ++ C+ G+ + S+E
Sbjct: 2814 CGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSER 2873
Query: 1569 KVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQER 1626
C G W Q C + C P ++G S V C +
Sbjct: 2874 ---------TCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGY 2924
Query: 1627 EKLPIL---CTKEGLWTQEFKLCENLQGECPPPPSELN------------SVEYKCEQGY 1671
+L C+ G WT C L C P N +V Y+C GY
Sbjct: 2925 YATGLLSRHCSVNGTWTGSDPEC--LVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGY 2982
Score = 38.9 bits (89), Expect = 0.045
Identities = 41/167 (24%), Positives = 60/167 (35%), Gaps = 39/167 (23%)
Query: 1513 LWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVR 1571
LWS C+ L C P N + + VGT Y C GY++ AE
Sbjct: 2518 LWSEAIPLCQALSCGLPEAPKNGMVF-----GKEYTVGTKAMYSCSEGYHLQAGAEATA- 2571
Query: 1572 NKLLKIQCLEGGIWEQGS----CIPVVCEPPPP----------VFEGMYECTNGFSLDSQ 1617
+CL+ G+W + C+PV C +FE Y+ +Q
Sbjct: 2572 ------ECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQ------FQAQ 2619
Query: 1618 CVLNCN---QEREKLPILCTKEGLWT--QEFKLCENLQ-GECPPPPS 1658
+L C+ + I C G W+ C + GE P PP+
Sbjct: 2620 LMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPN 2666
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 51.6 bits (122), Expect = 7e-06
Identities = 46/184 (25%), Positives = 75/184 (40%), Gaps = 35/184 (19%)
Query: 1423 CQRGFALQASSGQYIRPMQKEILLTCSSGH-WD-QNVSCLPVDCGVP-DPS--LVNYANF 1477
C GF L +S + C H W Q C+P+ CG P +P+ N + F
Sbjct: 2707 CNPGFRLVGTS-----------VRICLQDHKWSGQTPVCVPITCGHPGNPAHGFTNGSEF 2755
Query: 1478 SCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANL 1536
+ ++ F +C LQG+S C +G WS P C++ C P + NA
Sbjct: 2756 NLNDVVNF------TCNTGYLLQGVSR-AQCRSNGQWSSPLPTCRVVNCSDPGFVENAIR 2808
Query: 1537 LLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVV 1594
++ + G Y CK G+Y+ S+ + C+ G+W++ C+ +
Sbjct: 2809 HGQQNFPESFEYGMSILYHCKKGFYLLGSS---------ALTCMANGLWDRSLPKCLAIS 2859
Query: 1595 CEPP 1598
C P
Sbjct: 2860 CGHP 2863
Score = 51.6 bits (122), Expect = 7e-06
Identities = 59/257 (22%), Positives = 85/257 (33%), Gaps = 49/257 (19%)
Query: 1459 CLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPE 1518
C V CG +P S+G F +C K GL C +G W+
Sbjct: 2974 CEAVSCG--NPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMT-RHCTANGTWTGTA 3030
Query: 1519 VYCKL-ECDAPPIILNANLLLPHCLQDNHDV--GTICKYECKPGYYVAESAEGKVRNKLL 1575
C + C P + N +Q D Y+C PGY + +R
Sbjct: 3031 PDCTIISCGDPGTLANG-------IQFGTDFTFNKTVSYQCNPGYVMEAVTSATIR---- 3079
Query: 1576 KIQCLEGGIWEQGS--CIPVVCEPPPPVFEGM-------------YECTNGFSLDSQCVL 1620
C + G W C V+C PPPV G Y C +G+ L +L
Sbjct: 3080 ---CTKDGRWNPSKPVCKAVLCPQPPPVQNGTVEGSDFRWGSSISYSCMDGYQLSHSAIL 3136
Query: 1621 NC-------NQEREKLPILCTKEG------LWTQEFKLCENLQGECPPPPSELNSVEYKC 1667
+C + + LP+ C G L + F + +C P + S C
Sbjct: 3137 SCEGRGVWKGEIPQCLPVFCGDPGIPAEGRLSGKSFTYKSEVFFQCKSPFILVGSSRRVC 3196
Query: 1668 EQGYGIGAVCSPLCVIP 1684
Q G + P C+ P
Sbjct: 3197 -QADGTWSGIQPTCIDP 3212
Score = 50.4 bits (119), Expect = 2e-05
Identities = 71/329 (21%), Positives = 119/329 (36%), Gaps = 71/329 (21%)
Query: 1423 CQRGFALQASSGQYIRPMQKEILLTC-SSGHWDQNV-SCLPVDCG---VPDPSLVNYANF 1477
C++GF L SS LTC ++G WD+++ CL + CG VP +++ F
Sbjct: 2828 CKKGFYLLGSSA-----------LTCMANGLWDRSLPKCLAISCGHPGVPANAVLTGELF 2876
Query: 1478 SCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLE----CDAPPIILN 1533
+ + R S S + + C ED WS +C C P +
Sbjct: 2877 TYGAVVHYSCRGSESLIG-------NDTRVCQEDSHWSGALPHCTGNNPGFCGDPGTPAH 2929
Query: 1534 ANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWE--QGSCI 1591
+ L D+ ++ ++ C+ G+ + S E CL G W Q C
Sbjct: 2930 GSRL-----GDDFKTKSLLRFSCEMGHQLRGSPERT---------CLLNGSWSGLQPVCE 2975
Query: 1592 PVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKLPIL---CTKEGLWTQEFKLCEN 1648
V C P GM ++G S + C + + ++ CT G WT C
Sbjct: 2976 AVSCGNPGTPTNGMIVSSDGILFSSSVIYACWEGYKTSGLMTRHCTANGTWTGTAPDCTI 3035
Query: 1649 LQGECPPPPSELNSVEYKCEQGYG--IGAVCSPLCVIPPSDPVMLPENITADTLEHWMEP 1706
+ C P + N +++ + + + C+P V ME
Sbjct: 3036 IS--CGDPGTLANGIQFGTDFTFNKTVSYQCNPGYV---------------------MEA 3072
Query: 1707 VKVQSIVCTGRRQWHPDPVLVHCIQSCEP 1735
V +I CT +W+P + + +P
Sbjct: 3073 VTSATIRCTKDGRWNPSKPVCKAVLCPQP 3101
Score = 47.8 bits (112), Expect = 1e-04
Identities = 54/209 (25%), Positives = 79/209 (37%), Gaps = 39/209 (18%)
Query: 1483 TKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHC 1541
TK L R SC +L+G SP TCL +G WS + C+ + C P N ++
Sbjct: 2939 TKSLLR--FSCEMGHQLRG-SPERTCLLNGSWSGLQPVCEAVSCGNPGTPTNGMIVSSDG 2995
Query: 1542 LQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGS--CIPVVCEPPP 1599
+ + V Y C GY + L+ C G W + C + C P
Sbjct: 2996 ILFSSSV----IYACWEGYKTSG---------LMTRHCTANGTWTGTAPDCTIISCGDPG 3042
Query: 1600 PVFEGMYECTNGFSLDSQCVLNCN-----QEREKLPILCTKEGLWTQEFKLCENLQGECP 1654
+ G+ T+ F+ + CN + I CTK+G W +C+ + CP
Sbjct: 3043 TLANGIQFGTD-FTFNKTVSYQCNPGYVMEAVTSATIRCTKDGRWNPSKPVCKAVL--CP 3099
Query: 1655 PPPSELN------------SVEYKCEQGY 1671
PP N S+ Y C GY
Sbjct: 3100 QPPPVQNGTVEGSDFRWGSSISYSCMDGY 3128
Score = 45.8 bits (107), Expect = 4e-04
Identities = 62/250 (24%), Positives = 93/250 (37%), Gaps = 40/250 (16%)
Query: 1429 LQASSGQYIRPMQKEILLTC-SSGHW---DQNVSCLPVDCG-VPDPSLVNYANFSCSEGT 1483
L S G Y+ + LL C ++G W D+ SC + CG + P N G
Sbjct: 2587 LSCSPGYYLEGWR---LLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGA 2643
Query: 1484 KFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCL 1542
+ C+ L G S CL +GLWS E C C +P I+N H
Sbjct: 2644 TAIFTCNTGYT----LVG-SHVRECLANGLWSGSETRCLAGHCGSPDPIVNG-----HIS 2693
Query: 1543 QDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIW--EQGSCIPVVCEPPPP 1600
D Y+C PG+ + ++ ++I CL+ W + C+P+ C P
Sbjct: 2694 GDGFSYRDTVVYQCNPGFRLVGTS--------VRI-CLQDHKWSGQTPVCVPITCGHPGN 2744
Query: 1601 VFEGMYECTNG--FSLDSQCVLNCNQE---REKLPILCTKEGLWTQEFKLCENLQGECPP 1655
G TNG F+L+ CN + C G W+ C + C
Sbjct: 2745 PAHGF---TNGSEFNLNDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTCRVV--NCSD 2799
Query: 1656 PPSELNSVEY 1665
P N++ +
Sbjct: 2800 PGFVENAIRH 2809
Score = 45.4 bits (106), Expect = 5e-04
Identities = 62/258 (24%), Positives = 97/258 (37%), Gaps = 47/258 (18%)
Query: 1453 WDQNVS-CLPVDCGVPD-PSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLE 1510
WD C V CG+P+ P ++ + +K + C + Q + C E
Sbjct: 2484 WDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECHEGFKLESSQQATA---VCQE 2540
Query: 1511 DGLWS---LPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAE 1567
DGLWS P + C + L+ +++ ++ G C PGYY+ E
Sbjct: 2541 DGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLNEYGAQVLLSCSPGYYL----E 2596
Query: 1568 GKVRNKLLKIQCLEGGIW----EQGSCIPVVCE----PPPPVFEG---MYECTNGFSLDS 1616
G +LL+ C G W E+ SC + C PP G +Y T F+ ++
Sbjct: 2597 GW---RLLR--CQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLTVYGATAIFTCNT 2651
Query: 1617 QCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN------------SVE 1664
L + RE C GLW+ C L G C P +N +V
Sbjct: 2652 GYTLVGSHVRE-----CLANGLWSGSETRC--LAGHCGSPDPIVNGHISGDGFSYRDTVV 2704
Query: 1665 YKCEQGYGIGAVCSPLCV 1682
Y+C G+ + +C+
Sbjct: 2705 YQCNPGFRLVGTSVRICL 2722
Score = 39.3 bits (90), Expect = 0.035
Identities = 32/123 (26%), Positives = 53/123 (43%), Gaps = 17/123 (13%)
Query: 1548 VGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGS----CIPVVCEPPPPVFE 1603
VG+ Y CKPGY + + R L G+++ S C V C P
Sbjct: 2452 VGSKVHYFCKPGYRMVGHSNATCRRNPL-------GMYQWDSLTPLCQAVSCGIPESPGN 2504
Query: 1604 GMYECTNGFSLDSQCVLNCN-----QEREKLPILCTKEGLWTQEFKLCENLQGECPPPPS 1658
G + N F+LDS+ V C+ + ++ +C ++GLW+ + K CP +
Sbjct: 2505 GSF-TGNEFTLDSKVVYECHEGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEA 2563
Query: 1659 ELN 1661
+L+
Sbjct: 2564 QLS 2566
Score = 38.5 bits (88), Expect = 0.059
Identities = 49/189 (25%), Positives = 66/189 (34%), Gaps = 44/189 (23%)
Query: 1422 TCQRGFALQASSGQYIRPMQKEILLTCSS-GHWDQNV-SCLPVDCGVPDPSLVNYANFSC 1479
+C G+ L S+ +L+C G W + CLPV CG DP + S
Sbjct: 3123 SCMDGYQLSHSA-----------ILSCEGRGVWKGEIPQCLPVFCG--DPGIPAEGRLSG 3169
Query: 1480 SEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYC----KLECDAPPIILNAN 1535
T + C P L G S + C DG WS + C C P
Sbjct: 3170 KSFT-YKSEVFFQCKSPFILVGSSRRV-CQADGTWSGIQPTCIDPAHNTCPDPGT----- 3222
Query: 1536 LLLPHCLQDN----HDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWE--QGS 1589
PH N ++VG+ + C+ GY++ S CL W Q
Sbjct: 3223 ---PHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTR---------TCLANLTWSGIQTE 3270
Query: 1590 CIPVVCEPP 1598
CIP C P
Sbjct: 3271 CIPHACRQP 3279
Score = 32.7 bits (73), Expect = 3.3
Identities = 13/37 (35%), Positives = 20/37 (54%), Gaps = 3/37 (8%)
Query: 1524 ECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGY 1560
+C PP + A +L D+ ++G KY+C PGY
Sbjct: 2258 KCQPPPAVPQAEMLTE---DDDFEIGDFVKYQCHPGY 2291
>gi|117320518 complement factor H-related 4 [Homo sapiens]
Length = 331
Score = 50.4 bits (119), Expect = 2e-05
Identities = 59/220 (26%), Positives = 85/220 (38%), Gaps = 44/220 (20%)
Query: 1477 FSCSEGTKFLKRCSISCVPPAKLQGLSPW--LTCLEDGLWSLPEVYCKLECDAPPIILNA 1534
F + G + C + V P+ S W + C +DG WS P V C C I +
Sbjct: 44 FPAAAGQSYSYYCDQNFVTPSG----SYWDYIHCTQDG-WS-PTVPCLRTCSKSDIEIEN 97
Query: 1535 NLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVV 1594
+ + + +Y+CKPGY A+ N I CL+ G Q CI
Sbjct: 98 GFISES--SSIYILNKEIQYKCKPGYATADG------NSSGSITCLQNGWSAQPICIK-F 148
Query: 1595 CEPPPPVFEGMYECTNGF------SLDSQCV--LNCNQEREKLPILCTKEGLWTQEFKLC 1646
C+ PVFE +NG +LD +C + I+C ++G W+ F C
Sbjct: 149 CD--MPVFENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDG-WS-HFPTC 204
Query: 1647 ENLQGECPPPPSELNS---------------VEYKCEQGY 1671
N +C PPP N VEY+C+ Y
Sbjct: 205 YNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQSYY 244
>gi|5454086 sushi-repeat-containing protein, X-linked [Homo sapiens]
Length = 464
Score = 49.3 bits (116), Expect = 3e-05
Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 19/101 (18%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSG-HWDQNVSCLPVDCGVPDPSLVNYAN 1476
+C I CQ+G+ L SS LL C S W V C C P+L AN
Sbjct: 84 RCDIRCQKGYELHGSS-----------LLICQSNKRWSDKVICKQKRC----PTLAMPAN 128
Query: 1477 --FSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGLWS 1515
F C +G F RC C P L+G +TC+++ WS
Sbjct: 129 GGFKCVDGAYFNSRCEYYCSPGYTLKG-ERTVTCMDNKAWS 168
Score = 32.7 bits (73), Expect = 3.3
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 14/111 (12%)
Query: 1488 RCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHD 1547
RC I C +L G S L C + WS +V CK + P + + AN C+ D
Sbjct: 84 RCDIRCQKGYELHG-SSLLICQSNKRWS-DKVICKQK-RCPTLAMPANGGFK-CV-DGAY 138
Query: 1548 VGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPP 1598
+ C+Y C PGY + +G+ + C++ W V EPP
Sbjct: 139 FNSRCEYYCSPGY----TLKGE-----RTVTCMDNKAWSGRPASCVDMEPP 180
>gi|54792787 complement factor H-related 3 [Homo sapiens]
Length = 330
Score = 47.8 bits (112), Expect = 1e-04
Identities = 57/248 (22%), Positives = 89/248 (35%), Gaps = 37/248 (14%)
Query: 1448 CSSGHWDQNVSCLPVDCGVPDPSLVNYANFSCSEGTKFLKRCS--ISCVPPAKLQGLSPW 1505
C+ W V CL C P L N ++ + G KF++ S ++C P L
Sbjct: 72 CTQNGWSPAVPCLR-KCYFP--YLEN--GYNQNYGRKFVQGNSTEVACHPGYGLPKAQTT 126
Query: 1506 LTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAES 1565
+TC E G P C I + + + + +Y+CKPGY A+
Sbjct: 127 VTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISES--SSIYILNKEIQYKCKPGYATADG 184
Query: 1566 AEGKVRNKLLKIQCLEGGIWEQGSCI--PVVCEPPPPVFEG----------------MYE 1607
N I CL+ G Q CI C PPPP+ G Y+
Sbjct: 185 ------NSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQ 238
Query: 1608 CTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENL----QGECPPPPSELNSV 1663
C + L + C+ P C + T+E N+ + + +++
Sbjct: 239 CQPYYELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTI 298
Query: 1664 EYKCEQGY 1671
E+ C+ GY
Sbjct: 299 EFMCKLGY 306
>gi|4502503 complement component 4 binding protein, alpha chain
precursor [Homo sapiens]
Length = 597
Score = 47.4 bits (111), Expect = 1e-04
Identities = 67/327 (20%), Positives = 109/327 (33%), Gaps = 86/327 (26%)
Query: 1458 SCLPVDCGVPDPS----------LVNYAN---FSCSEGTKFLKRCSISCVPPAKLQGLSP 1504
+C + C PD S + NY + F C +G I C +K P
Sbjct: 233 TCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPP 292
Query: 1505 WLTCLEDGLWSLPEV-YCKLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVA 1563
C + +LP++ + E P +D + VGT+ +Y C PGY
Sbjct: 293 --ACEPNSCINLPDIPHASWETYPRPT-----------KEDVYVVGTVLRYRCHPGY--- 336
Query: 1564 ESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVCEPPPPVFEGMYECTNGFSLDSQCV---- 1619
++ + C + W +C P P + G + CV
Sbjct: 337 ----KPTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYG 392
Query: 1620 ----LNCNQEREKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN-------------- 1661
+C+ E + +C +G W+ C ++ C PP +
Sbjct: 393 DEISFSCH-ETSRFSAICQGDGTWSPRTPSCGDI---CNFPPKIAHGHYKQSSSYSFFKE 448
Query: 1662 SVEYKCEQGYGI----------------GAVCSPLCVIP---------PSDPVMLPENIT 1696
+ Y+C++GY + C LC P D + PEN+T
Sbjct: 449 EIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVEPENVT 508
Query: 1697 ADTLEHWMEPVKVQSIVCTGRRQWHPD 1723
+ V QSI C+G R W+P+
Sbjct: 509 IQ-CDSGYGVVGPQSITCSGNRTWYPE 534
Score = 44.3 bits (103), Expect = 0.001
Identities = 51/228 (22%), Positives = 81/228 (35%), Gaps = 56/228 (24%)
Query: 1436 YIRPMQKEILLTCSSGHWDQNVSCLPVDCGVP------------DPSLVNYANFSCSEGT 1483
Y+R + L S G W N C+ C P D S + FSCSEG
Sbjct: 85 YVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGF 144
Query: 1484 KFLKRCSISCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKL-ECDAPPIILNANLLLPHCL 1542
+ + C + G WS P C++ +C PP I N H
Sbjct: 145 FLIGSTTSRCEVQDRGVG------------WSHPLPQCEIVKCKPPPDIRNGR----HSG 188
Query: 1543 QDN-HDVGTICKYECKPGYYVA--ESAEGKVRNKLLKIQCLEGGIWEQG--SCIPVVCEP 1597
++N + G Y C P + + S V N+ + G+W +C + C
Sbjct: 189 EENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI-------GVWRPSPPTCEKITCRK 241
Query: 1598 PP-----------PVFEG----MYECTNGFSLDSQCVLNCNQEREKLP 1630
P P++ +++C GF L V++C+ + + P
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNP 289
Score = 42.0 bits (97), Expect = 0.005
Identities = 41/180 (22%), Positives = 63/180 (35%), Gaps = 31/180 (17%)
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGI 1584
C PP + A + + GT KY C PGY + S + + C G
Sbjct: 50 CGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQ--------TLTCNSDGE 101
Query: 1585 WEQGS-CIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKLPILCTK-----EGL 1638
W + CI C P + G E S SQ +C++ + ++ G+
Sbjct: 102 WVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGV 161
Query: 1639 -WTQEFKLCENLQGECPPPPSELN--------------SVEYKCEQGYGIGAVCSPLCVI 1683
W+ CE + +C PPP N SV Y C+ + + S C +
Sbjct: 162 GWSHPLPQCEIV--KCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTV 219
Score = 40.0 bits (92), Expect = 0.020
Identities = 42/210 (20%), Positives = 73/210 (34%), Gaps = 48/210 (22%)
Query: 1492 SCVPPAKLQGLSPWLTCLEDGLWSLPEVYCKLECDAPPIILNANLLLPHCLQDNHDVGTI 1551
+C+P + LTC DG W C P + N + + L G+
Sbjct: 80 TCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLS----FGSQ 135
Query: 1552 CKYECKPGYYVAESAEGKVRNKLLKIQCLEGGI-WEQG--SCIPVVCEPPPPVFEGM--- 1605
++ C G+++ S + + + G+ W C V C+PPP + G
Sbjct: 136 IEFSCSEGFFLIGSTTSRC-------EVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSG 188
Query: 1606 ------------YECTNGFSLDSQCVLNCNQEREKLPILCTKEGLWTQEFKLCENLQGEC 1653
Y C FSL ++C E E + G+W CE +
Sbjct: 189 EENFYAYGFSVTYSCDPRFSLLGHASISCTVENETI-------GVWRPSPPTCEKITCRK 241
Query: 1654 P------------PPPSELNSVEYKCEQGY 1671
P P + +++ +KC++G+
Sbjct: 242 PDVSHGEMVSGFGPIYNYKDTIVFKCQKGF 271
>gi|110611237 coagulation factor XIII B subunit precursor [Homo
sapiens]
Length = 661
Score = 47.4 bits (111), Expect = 1e-04
Identities = 61/251 (24%), Positives = 87/251 (34%), Gaps = 27/251 (10%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANF 1477
K + C G+ ++ ++E TC++ W C C PD S ++
Sbjct: 54 KLSFFCLAGYTTESG--------RQEEQTTCTTEGWSPEPRCFK-KCTKPDLSNGYISDV 104
Query: 1478 SCSEGTKFLKRCSISCVPPAKLQGLSPW--LTCLEDGLWSLPEVYCKLECDAPPIILNAN 1535
K + C K G + CL DG S P + E P + N N
Sbjct: 105 KLLY--KIQENMRYGCASGYKTTGGKDEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGN 162
Query: 1536 LLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPVVC 1595
Q V +YEC GYY +A GK K +++CL G C + C
Sbjct: 163 Y---STTQKTFKVKDKVQYECATGYY---TAGGK---KTEEVECLTYGWSLTPKCTKLKC 213
Query: 1596 EPPPPVFEGMYECTNGFSLDSQCVLNCNQEREKLP----ILCTKEGLWTQEFKLCENLQG 1651
+ G + + V E L I C G W E +CE +
Sbjct: 214 SSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFG-WYPESPVCEGRRN 272
Query: 1652 ECPPPPSELNS 1662
CPPPP +NS
Sbjct: 273 RCPPPPLPINS 283
Score = 43.5 bits (101), Expect = 0.002
Identities = 46/181 (25%), Positives = 65/181 (35%), Gaps = 59/181 (32%)
Query: 1525 CDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGI 1584
C PP+ +N+ + H H G I EC+ + + SAE I+C +G
Sbjct: 274 CPPPPLPINSKIQT-HSTTYRH--GEIVHIECELNFEIHGSAE---------IRCEDGKW 321
Query: 1585 WEQGSCIP----VVCEPPPPVFEGM---------------YECTNGFSLDSQCVLNCNQE 1625
E CI V CE PP + G Y C +G+ L + CN+
Sbjct: 322 TEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNR- 380
Query: 1626 REKLPILCTKEGLWTQEFKLCENLQGECPPPPSELN---------------SVEYKCEQG 1670
G WT + EN + C PP +N SVEY+C +
Sbjct: 381 -----------GKWTLPPECVENNE-NCKHPPVVMNGAVADGILASYATGSSVEYRCNEY 428
Query: 1671 Y 1671
Y
Sbjct: 429 Y 429
>gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]
Length = 490
Score = 47.4 bits (111), Expect = 1e-04
Identities = 43/147 (29%), Positives = 64/147 (43%), Gaps = 14/147 (9%)
Query: 1418 KCAITCQRGFALQASSGQYIRPMQKEILLTCSSGHWDQNVSCLPVDCGVPDPSLVNYANF 1477
K ITC GF ++ + + L G W+ C C P S Y N
Sbjct: 142 KLIITCHEGFKIRYPD------LHNMVSLCRDDGTWNNLPICQ--GCLRPLASSNGYVNI 193
Query: 1478 SCSEGTKFLKRCSIS--CVPPAKLQGLSPWLTCLEDGLWSLPEVYC-KLE-CDAPPIILN 1533
S + T F IS C P KL G S +L CL++ +WS C LE C PP++ +
Sbjct: 194 SELQ-TSFPVGTVISYRCFPGFKLDG-SAYLECLQNLIWSSSPPRCLALEVCPLPPMVSH 251
Query: 1534 ANLLLPHCLQDNHDVGTICKYECKPGY 1560
+ + + ++ GT+ ++ C PGY
Sbjct: 252 GDFVCHPRPCERYNHGTVVEFYCDPGY 278
Score = 45.8 bits (107), Expect = 4e-04
Identities = 54/197 (27%), Positives = 83/197 (42%), Gaps = 36/197 (18%)
Query: 1423 CQRGFALQASSGQYIRPMQKEILLTCSSGH--W--DQNVSCLPVDCGVPDPSLVNYANFS 1478
CQ GF L+ ++ K + L +G W N C+ DC +P N +
Sbjct: 85 CQDGFKLKGAT--------KRLCLKHFNGTLGWIPSDNSICVQEDCRIPQIEDAEIHNKT 136
Query: 1479 CSEGTKFLKRCSISCVPPAKLQ--GLSPWLT-CLEDGLWS-LPEVYCKLECDAPPIILNA 1534
G K + I+C K++ L ++ C +DG W+ LP C+ C P N
Sbjct: 137 YRHGEKLI----ITCHEGFKIRYPDLHNMVSLCRDDGTWNNLP--ICQ-GCLRPLASSNG 189
Query: 1535 NLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLEGGIWEQG--SCIP 1592
+ + LQ + VGT+ Y C PG+ + SA ++CL+ IW C+
Sbjct: 190 YVNISE-LQTSFPVGTVISYRCFPGFKLDGSA---------YLECLQNLIWSSSPPRCLA 239
Query: 1593 V-VCEPPPPVFEGMYEC 1608
+ VC PP V G + C
Sbjct: 240 LEVCPLPPMVSHGDFVC 256
>gi|62912468 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 47.0 bits (110), Expect = 2e-04
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 26/167 (15%)
Query: 1442 KEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
K+ L +S WD + C C PDP LVN FS S + + C L+
Sbjct: 58 KKTLFCNASKEWDNTTTECRLGHC--PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILK 114
Query: 1501 GLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPG 1559
G S CLED W+ P CK +CD P N + + +N +G+ Y C+
Sbjct: 115 G-SNRSQCLEDHTWAPPFPICKSRDCDPP-----GNPVHGYFEGNNFTLGSTISYYCEDR 168
Query: 1560 YYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPV---VCEPPPPVFE 1603
YY+ E QC++G E S +PV + E P P E
Sbjct: 169 YYLVGVQEQ---------QCVDG---EWSSALPVCKLIQEAPKPECE 203
>gi|62912466 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 47.0 bits (110), Expect = 2e-04
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 26/167 (15%)
Query: 1442 KEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
K+ L +S WD + C C PDP LVN FS S + + C L+
Sbjct: 57 KKTLFCNASKEWDNTTTECRLGHC--PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILK 113
Query: 1501 GLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPG 1559
G S CLED W+ P CK +CD P N + + +N +G+ Y C+
Sbjct: 114 G-SNRSQCLEDHTWAPPFPICKSRDCDPP-----GNPVHGYFEGNNFTLGSTISYYCEDR 167
Query: 1560 YYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPV---VCEPPPPVFE 1603
YY+ E QC++G E S +PV + E P P E
Sbjct: 168 YYLVGVQEQ---------QCVDG---EWSSALPVCKLIQEAPKPECE 202
>gi|62912464 complement component 4 binding protein, beta chain
isoform 1 precursor [Homo sapiens]
Length = 252
Score = 47.0 bits (110), Expect = 2e-04
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 26/167 (15%)
Query: 1442 KEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
K+ L +S WD + C C PDP LVN FS S + + C L+
Sbjct: 58 KKTLFCNASKEWDNTTTECRLGHC--PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILK 114
Query: 1501 GLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPG 1559
G S CLED W+ P CK +CD P N + + +N +G+ Y C+
Sbjct: 115 G-SNRSQCLEDHTWAPPFPICKSRDCDPP-----GNPVHGYFEGNNFTLGSTISYYCEDR 168
Query: 1560 YYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPV---VCEPPPPVFE 1603
YY+ E QC++G E S +PV + E P P E
Sbjct: 169 YYLVGVQEQ---------QCVDG---EWSSALPVCKLIQEAPKPECE 203
>gi|62912462 complement component 4 binding protein, beta chain
isoform 2 precursor [Homo sapiens]
Length = 251
Score = 47.0 bits (110), Expect = 2e-04
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 26/167 (15%)
Query: 1442 KEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
K+ L +S WD + C C PDP LVN FS S + + C L+
Sbjct: 57 KKTLFCNASKEWDNTTTECRLGHC--PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILK 113
Query: 1501 GLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPG 1559
G S CLED W+ P CK +CD P N + + +N +G+ Y C+
Sbjct: 114 G-SNRSQCLEDHTWAPPFPICKSRDCDPP-----GNPVHGYFEGNNFTLGSTISYYCEDR 167
Query: 1560 YYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPV---VCEPPPPVFE 1603
YY+ E QC++G E S +PV + E P P E
Sbjct: 168 YYLVGVQEQ---------QCVDG---EWSSALPVCKLIQEAPKPECE 202
>gi|4502505 complement component 4 binding protein, beta chain isoform
1 precursor [Homo sapiens]
Length = 252
Score = 47.0 bits (110), Expect = 2e-04
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 26/167 (15%)
Query: 1442 KEILLTCSSGHWDQNVS-CLPVDCGVPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQ 1500
K+ L +S WD + C C PDP LVN FS S + + C L+
Sbjct: 58 KKTLFCNASKEWDNTTTECRLGHC--PDPVLVN-GEFSSSGPVNVSDKITFMCNDHYILK 114
Query: 1501 GLSPWLTCLEDGLWSLPEVYCK-LECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPG 1559
G S CLED W+ P CK +CD P N + + +N +G+ Y C+
Sbjct: 115 G-SNRSQCLEDHTWAPPFPICKSRDCDPP-----GNPVHGYFEGNNFTLGSTISYYCEDR 168
Query: 1560 YYVAESAEGKVRNKLLKIQCLEGGIWEQGSCIPV---VCEPPPPVFE 1603
YY+ E QC++G E S +PV + E P P E
Sbjct: 169 YYLVGVQEQ---------QCVDG---EWSSALPVCKLIQEAPKPECE 203
>gi|42476320 sushi domain containing 1 [Homo sapiens]
Length = 747
Score = 47.0 bits (110), Expect = 2e-04
Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 23/137 (16%)
Query: 1458 SCLPVDCG----VPDPSLVNYANFSCSEGTKFLKRCSISCVPPAKLQGLSPWLTCLEDGL 1513
SC +DCG VPD ++ S ++ R VP + +C G
Sbjct: 173 SCTEIDCGTPPEVPDGYIIGNYTSSLGSQVRYACREGFFSVPEDTVS------SCTGLGT 226
Query: 1514 WSLPEVYC-KLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRN 1572
W P+++C ++ C PP + +A L+ H + +G + +Y C+ G+ ES GK+ +
Sbjct: 227 WESPKLHCQEINCGNPPEMRHAILVGNH----SSRLGGVARYVCQEGF---ESPGGKITS 279
Query: 1573 KLLKIQCLEGGIWEQGS 1589
C E G W + +
Sbjct: 280 -----VCTEKGTWREST 291
Score = 31.6 bits (70), Expect = 7.2
Identities = 26/134 (19%), Positives = 52/134 (38%), Gaps = 18/134 (13%)
Query: 1522 KLECDAPPIILNANLLLPHCLQDNHDVGTICKYECKPGYYVAESAEGKVRNKLLKIQCLE 1581
+++C PP + + ++ + +G+ +Y C+ G++ E V + C
Sbjct: 176 EIDCGTPPEVPDGYIIGNY----TSSLGSQVRYACREGFFSVP--EDTVSS------CTG 223
Query: 1582 GGIWEQGS--CIPVVCEPPPPVFEGMYECTNGFSLDSQCVLNCNQERE----KLPILCTK 1635
G WE C + C PP + + + L C + E K+ +CT+
Sbjct: 224 LGTWESPKLHCQEINCGNPPEMRHAILVGNHSSRLGGVARYVCQEGFESPGGKITSVCTE 283
Query: 1636 EGLWTQEFKLCENL 1649
+G W + C +
Sbjct: 284 KGTWRESTLTCTEI 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,169,425
Number of Sequences: 37866
Number of extensions: 4488362
Number of successful extensions: 11323
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 10742
Number of HSP's gapped (non-prelim): 421
length of query: 1791
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1674
effective length of database: 13,817,196
effective search space: 23129986104
effective search space used: 23129986104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.