Guide to the Human Genome
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Search of human proteins with 116008194

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116008194 myosin light chain kinase isoform 3A [Homo
sapiens]
         (1863 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]     3759   0.0  
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]      3736   0.0  
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]     3437   0.0  
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]      3413   0.0  
gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]        313   1e-84
gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]        306   9e-83
gi|110349719 titin isoform N2-A [Homo sapiens]                        295   3e-79
gi|110349717 titin isoform novex-2 [Homo sapiens]                     295   3e-79
gi|110349713 titin isoform novex-1 [Homo sapiens]                     295   3e-79
gi|110349715 titin isoform N2-B [Homo sapiens]                        295   3e-79
gi|146219832 myosin light chain kinase 3 [Homo sapiens]               236   2e-61
gi|167466233 myosin light chain kinase family, member 4 [Homo sa...   221   7e-57
gi|14993776 skeletal myosin light chain kinase [Homo sapiens]         220   1e-56
gi|89363047 death-associated protein kinase 1 [Homo sapiens]          200   9e-51
gi|4557511 death-associated protein kinase 3 [Homo sapiens]           191   6e-48
gi|14670383 death-associated kinase 2 [Homo sapiens]                  189   3e-47
gi|157785645 SPEG complex locus [Homo sapiens]                        186   2e-46
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]          185   4e-46
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]           185   4e-46
gi|118572606 hemicentin 1 [Homo sapiens]                              179   2e-44
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                   171   5e-42
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                   171   5e-42
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                   171   5e-42
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ...   158   5e-38
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s...   158   5e-38
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor...   154   6e-37
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo...   154   6e-37
gi|109150416 peroxidasin [Homo sapiens]                               152   2e-36
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...   151   7e-36
gi|4758194 serine/threonine kinase 17B [Homo sapiens]                 147   1e-34

>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
          Length = 1863

 Score = 3759 bits (9749), Expect = 0.0
 Identities = 1863/1863 (100%), Positives = 1863/1863 (100%)

Query: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60

Query: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
            SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240

Query: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
            KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300

Query: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
            QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG
Sbjct: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360

Query: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
            LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP
Sbjct: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420

Query: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
            QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR
Sbjct: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480

Query: 481  DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
            DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 481  DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540

Query: 541  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 541  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
            HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
            NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
            PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780

Query: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
            LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840

Query: 841  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
            GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 841  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900

Query: 901  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
            LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 901  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960

Query: 961  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
            GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 961  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020

Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
            GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080

Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
            HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140

Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
            TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200

Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
            MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260

Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
            VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320

Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
            AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380

Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
            DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500

Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
            KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560

Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
            ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620

Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680
            LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL
Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680

Query: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
            SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED
Sbjct: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740

Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
            VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE
Sbjct: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800

Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
            SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE
Sbjct: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860

Query: 1861 EEE 1863
            EEE
Sbjct: 1861 EEE 1863


>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
          Length = 1914

 Score = 3736 bits (9687), Expect = 0.0
 Identities = 1863/1914 (97%), Positives = 1863/1914 (97%), Gaps = 51/1914 (2%)

Query: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60

Query: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
            SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240

Query: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
            KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300

Query: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
            QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG
Sbjct: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360

Query: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
            LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP
Sbjct: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420

Query: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
            QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR
Sbjct: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480

Query: 481  DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
            DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 481  DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540

Query: 541  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 541  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
            HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
            NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
            PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780

Query: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
            LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840

Query: 841  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
            GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 841  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900

Query: 901  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
            LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 901  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960

Query: 961  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
            GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 961  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020

Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
            GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080

Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
            HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140

Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
            TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200

Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
            MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260

Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
            VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320

Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
            AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380

Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
            DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500

Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
            KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560

Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
            ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620

Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1654
            LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL                          
Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680

Query: 1655 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1689
                                     NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
Sbjct: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740

Query: 1690 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
            ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
Sbjct: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800

Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
            AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
Sbjct: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860

Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
            EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914


>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
          Length = 1794

 Score = 3437 bits (8911), Expect = 0.0
 Identities = 1739/1863 (93%), Positives = 1749/1863 (93%), Gaps = 69/1863 (3%)

Query: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60

Query: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
            SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240

Query: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
            KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300

Query: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
            QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA  
Sbjct: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358

Query: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
                                      PGLG   V+S +   R      R + FP  +   
Sbjct: 359  --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389

Query: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
             SQ+V  ++    R  + G        F E  P      S EV E+    + C       
Sbjct: 390  GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435

Query: 481  DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
                                    E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 436  ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471

Query: 541  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 472  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
            HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 532  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
            NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 592  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
            PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 652  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711

Query: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
            LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 712  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771

Query: 841  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
            GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 772  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831

Query: 901  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
            LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 832  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891

Query: 961  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
            GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 892  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951

Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
            GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 952  GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011

Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
            HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071

Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
            TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131

Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
            MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191

Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
            VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251

Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
            AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311

Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
            DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431

Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
            KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491

Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
            ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551

Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680
            LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL
Sbjct: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1611

Query: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
            SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED
Sbjct: 1612 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1671

Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
            VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE
Sbjct: 1672 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1731

Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
            SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE
Sbjct: 1732 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1791

Query: 1861 EEE 1863
            EEE
Sbjct: 1792 EEE 1794


>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
          Length = 1845

 Score = 3413 bits (8849), Expect = 0.0
 Identities = 1739/1914 (90%), Positives = 1749/1914 (91%), Gaps = 120/1914 (6%)

Query: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1    MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60

Query: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
            SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240

Query: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
            KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300

Query: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
            QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA  
Sbjct: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358

Query: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
                                      PGLG   V+S +   R      R + FP  +   
Sbjct: 359  --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389

Query: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
             SQ+V  ++    R  + G        F E  P      S EV E+    + C       
Sbjct: 390  GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435

Query: 481  DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
                                    E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 436  ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471

Query: 541  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 472  PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
            HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 532  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
            NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 592  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
            PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 652  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711

Query: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
            LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 712  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771

Query: 841  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
            GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 772  GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831

Query: 901  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
            LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 832  LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891

Query: 961  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
            GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 892  GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951

Query: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
            GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 952  GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011

Query: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
            HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071

Query: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
            TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131

Query: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
            MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191

Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
            VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251

Query: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
            AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311

Query: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
            DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431

Query: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
            KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491

Query: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
            ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551

Query: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1654
            LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL                          
Sbjct: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1611

Query: 1655 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1689
                                     NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
Sbjct: 1612 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1671

Query: 1690 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
            ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
Sbjct: 1672 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1731

Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
            AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
Sbjct: 1732 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1791

Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
            EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1792 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1845


>gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]
          Length = 154

 Score =  313 bits (802), Expect = 1e-84
 Identities = 154/154 (100%), Positives = 154/154 (100%)

Query: 1710 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1769
            MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1    MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60

Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 61   VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120

Query: 1830 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
            TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 121  TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 36/92 (39%), Positives = 51/92 (55%)

Query: 33  PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
           P F    R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I     F +D    G  SL+
Sbjct: 49  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108

Query: 93  IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
           I  V  +D  KYTC+A N  G    T EL VE
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)

Query: 602 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
           E +      +L  VA  KP   P F + + DL+V++GS      ++ G P PEV+W  + 
Sbjct: 27  ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86

Query: 661 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
             I+ES  F  +       SL I +V  +D   YTC+A NS GE    A L V+   +G
Sbjct: 87  QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)

Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
           F     E +P +     P F+  +  + V EG   RF CKI G P P+V W K +  ++ 
Sbjct: 36  FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91

Query: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
           S    +  +++G   L I  V  DD   YTC  VN  G+A+ +AEL ++ ++
Sbjct: 92  SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
           V P FS  ++D  V+EG      C + G P P + W  + Q I+ +R       E G   
Sbjct: 47  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106

Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
           L I D   +D   YTC A N+LG+ +C+A + V
Sbjct: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 36/127 (28%), Positives = 57/127 (44%), Gaps = 2/127 (1%)

Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
           T P     L S++ VS+A    +  E  +    P F    +  EV E    +F C++ G 
Sbjct: 18  TSPLNAEKLESEEDVSQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 75

Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
           P PEV WF +   +R        Y++ G+  L +      D   Y+C A N+ G+ +C+ 
Sbjct: 76  PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 135

Query: 501 TLQVERL 507
            L VE +
Sbjct: 136 ELIVETM 142



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)

Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
            E     P F + ++D+ V EG      C++   P   ++W  + ++++ ++ F I   E 
Sbjct: 43   EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
              CS+ I     +D   Y C A N  G+A C+ ++ V+     E
Sbjct: 103  GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)

Query: 690 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 749
           T     E   S  +V    +  V E     +P+F    R +    G +    C I G P 
Sbjct: 18  TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77

Query: 750 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
           P V W +D +++ +++ HF++  +ED   +L++  V      +Y     N +GE +C   
Sbjct: 78  PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136

Query: 809 LMLQ 812
           L+++
Sbjct: 137 LIVE 140



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)

Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
            K  + P   +   D +V  G +     K+ G       W K  + I+ES H +++  E+G
Sbjct: 44   KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103

Query: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
            +   I++   + CG     YT    N LG       L V
Sbjct: 104  NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139


>gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]
          Length = 153

 Score =  306 bits (785), Expect = 9e-83
 Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)

Query: 1710 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1769
            MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1    MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59

Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 60   VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119

Query: 1830 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
            TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 120  TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 36/92 (39%), Positives = 51/92 (55%)

Query: 33  PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
           P F    R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I     F +D    G  SL+
Sbjct: 48  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107

Query: 93  IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
           I  V  +D  KYTC+A N  G    T EL VE
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)

Query: 611 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
           +L  VA  KP   P F + + DL+V++GS      ++ G P PEV+W  +   I+ES  F
Sbjct: 35  FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94

Query: 670 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
             +       SL I +V  +D   YTC+A NS GE    A L V+   +G
Sbjct: 95  QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)

Query: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
           S+ +   F     E +P +     P F+  +  + V EG   RF CKI G P P+V W K
Sbjct: 28  SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83

Query: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
            +  ++ S    +  +++G   L I  V  DD   YTC  VN  G+A+ +AEL ++ ++
Sbjct: 84  DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)

Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 567
           V P FS  ++D  V+EG      C + G P P + W  + Q I+ +R       E G   
Sbjct: 46  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105

Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
           L I D   +D   YTC A N+LG+ +C+A + V
Sbjct: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 37/127 (29%), Positives = 57/127 (44%), Gaps = 3/127 (2%)

Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
           T P     L S+DV S+A    +  E  +    P F    +  EV E    +F C++ G 
Sbjct: 18  TSPLNAEKLESEDV-SQAFLEAVAEE--KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 74

Query: 441 PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
           P PEV WF +   +R        Y++ G+  L +      D   Y+C A N+ G+ +C+ 
Sbjct: 75  PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 134

Query: 501 TLQVERL 507
            L VE +
Sbjct: 135 ELIVETM 141



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)

Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1150
            E     P F + ++D+ V EG      C++   P   ++W  + ++++ ++ F I   E 
Sbjct: 42   EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
              CS+ I     +D   Y C A N  G+A C+ ++ V+     E
Sbjct: 102  GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)

Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
           ++PH   +P+F    R +    G +    C I G P P V W +D +++ +++ HF++  
Sbjct: 42  EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98

Query: 773 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
           +ED   +L++  V      +Y     N +GE +C   L+++
Sbjct: 99  DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)

Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
            K  + P   +   D +V  G +     K+ G       W K  + I+ES H +++  E+G
Sbjct: 43   KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102

Query: 1293 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1327
            +   I++   + CG     YT    N LG       L V
Sbjct: 103  NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  295 bits (755), Expect = 3e-79
 Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)

Query: 1097  APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
             AP FK++L++++V       L C+V+  P   + W   GK +     K+ I   +G    
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
             + I     +D  +Y+  A N  G    +  + V+                          
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 31020

Query: 1215  GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                             P K  +P  +        +R GE V +    +G      TW K 
Sbjct: 31021 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 31064

Query: 1275  RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
             +  I  + H +V  + + + L       ++  G Y +  +N+ G  Q  V L V D PDP
Sbjct: 31065 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 31124

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
             P G    SD+   S+ L+W   + DGGS + +Y +E   +  + W  +   R T + V +
Sbjct: 31125 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 31183

Query: 1394  LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
             L     Y+FRV A N +G S+PS+ SE T   E      +  E  D+     EV     +
Sbjct: 31184 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 31240

Query: 1454  INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
              ++ +++ + Y I E LG G+FG V R VE  ++K +  KF K     ++  +++EISI+
Sbjct: 31241 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 31299

Query: 1514  NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
             N   H  ++   ++FE    +VM+ E +SG ++FERI    FEL ERE + Y+ Q+ E +
Sbjct: 31300 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 31359

Query: 1574  EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
             +++H   I H D++PENI+   +  + IK+I+FG AR+L+   + ++LF  PE+ APEV 
Sbjct: 31360 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 31419

Query: 1634  NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
              ++ +  ATDMWS+G + Y+L                                       
Sbjct: 31420 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 31479

Query: 1655  ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
                         +R+  ++ LQHPWL +  + +  K +   + ++Y      +K  N V 
Sbjct: 31480 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 31538

Query: 1703  AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
             +  R+S    I      +S  G   + +    +E    VS   + AV EE  HVK     
Sbjct: 31539 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 31586

Query: 1763  TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
                           + CKIE Y    +V W+   + +  S  ++I Y EDG   L + D+
Sbjct: 31587 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 31631

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
                DD  Y CK VN  GE +  AEL V+ + E
Sbjct: 31632 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 31663



 Score =  217 bits (553), Expect = 7e-56
 Identities = 286/1264 (22%), Positives = 491/1264 (38%), Gaps = 198/1264 (15%)

Query: 31   EAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
            +APA F+    +  I++G     EG   G P   VTW +NG  +T   R    C I  T 
Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQR----CNITTTE 7920

Query: 90   SLVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
               I  +     ED G+Y C   N SG    + ++ +                       
Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE--------------------- 7959

Query: 147  PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
                         PP F  +L  V V  G      C++ G P+  V+W KG+  L+P+  
Sbjct: 7960 -------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTT 8006

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266
              +  +N +  L  + V+ +D G Y C   N  G+ S S  L++Q       SF R+ + 
Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE-QKLPPSFSRQLR- 8064

Query: 267  TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326
               DV++ V   +  +  +   E  + S             W  + +P           K
Sbjct: 8065 ---DVQETVGLPVVFDCAISGSEPISVS-------------WYKDGKP----------LK 8098

Query: 327  DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
            DSP    QT  L  T++    +  R             S +G+       P         
Sbjct: 8099 DSPNV--QTSFLDNTATLNIFKTDR-------------SLAGQYSCTATNP--------- 8134

Query: 387  PGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVA 446
              +GS    + ++ R I  EG+     P F+ +    +    ++  F C V+G    +V+
Sbjct: 8135 --IGS----ASSSARLILTEGKNP---PFFDIRLAPVDAVVGESADFECHVTGTQPIKVS 8185

Query: 447  WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-E 505
            W  +   +R   G  ++     S +L +LK    DSG Y+C A N  G+ SC+  L + E
Sbjct: 8186 WAKDSREIR-SGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKE 8244

Query: 506  RLAVMEVAPSFSSVLKDCAV-IEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTC 561
            RL    + PSF+  L +     EG  F L+  V G+    + W  N    QP      T 
Sbjct: 8245 RL----IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF 8300

Query: 562  EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
            +     L ++ A   D G YTC   N  G   C++ + + E              P KP 
Sbjct: 8301 KNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE--------------PKKP- 8345

Query: 622  APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
             P+F Q L+ + V +G  V ++  V G+ P  + WL  G EI+ S+   F        L 
Sbjct: 8346 -PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLE 8404

Query: 682  IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-----------DGTQPWFISKPRSV 730
            +++V   D+G Y C+A N AG   T++ +T+++             DG + +F+S+P+S+
Sbjct: 8405 LRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDG-RLFFVSEPQSI 8463

Query: 731  TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
                  +      + GDP P V W +         G   + Q  D   L ++      +G
Sbjct: 8464 RVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSG 8523

Query: 791  QYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPASCEDLCGGGVGADGGGSDRYGS 848
             Y  +  N  GE    V+L +     +    G  R       +   G G +    D    
Sbjct: 8524 LYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEE-EEIDIMEL 8582

Query: 849  LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTK 908
            L+   P   + +       D RG+L+     +Q  EE   + E+E+++ R    +K   +
Sbjct: 8583 LKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIE-RSERDEKEFEE 8641

Query: 909  TLSEDDLKEIPAEQMDFRANLQRQVKPK---TVSEEERKVHSPQQVDFRSVLAKKGTSKT 965
             +S    +    E +    +++ Q   K    V E + K++ P+      +   KGT K 
Sbjct: 8642 LVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPE----IKLSWYKGTEKL 8697

Query: 966  PVPEKVPPPKPATPDFRSVLGGKKKLPAEN----GSSSAETLNAKAVESSKPLSNAQPSG 1021
                     +P+     S+ G +  L  +N       +   +    + S+K L+  +P+ 
Sbjct: 8698 ---------EPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAK-LTVIEPAW 8747

Query: 1022 P--LKPVGNAKPAETLK-----PMGNAKP-----AETLKPMGNAKP--DENLKSASKEEL 1067
               L+ V   K  +T        + N K         LKP G  K   +  +   +  ++
Sbjct: 8748 ERHLQDV-TLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVEHKVHKLTIADV 8806

Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
            + + +    CK      T  E R E++     F +++Q++ V+E +    +C+VS D  A
Sbjct: 8807 RAEDQGQYTCKYEDL-ETSAELRIEAEPI--QFTKRIQNIVVSEHQSATFECEVSFD-DA 8862

Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAK-NDAGQAECSCQVT 1186
             + W      L  ++      +G    ++I    P+D G+Y  +A+    G+A  + ++ 
Sbjct: 8863 IVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELY 8922

Query: 1187 VDDAPASENTKAPEM-KSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP-PQIIQFP 1244
            +         K P++  SR P  ++P          ++  P  + PP  A P P ++  P
Sbjct: 8923 LTTKEIKLELKPPDIPDSRVPIPTMP----------IRAVPPEEIPPVVAPPIPLLLPTP 8972

Query: 1245 EDQK 1248
            E++K
Sbjct: 8973 EEKK 8976



 Score =  189 bits (480), Expect = 2e-47
 Identities = 207/837 (24%), Positives = 323/837 (38%), Gaps = 133/837 (15%)

Query: 26   SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
            S+ + E P F   P  +   +GA    E  ++G P   V+W+++ + + SG ++ +   +
Sbjct: 7392 SLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI---M 7448

Query: 86   RGTFSLVIHAVHEE--DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
               F   IH ++ +  D G+Y C+ATN  G+       T  GS A +             
Sbjct: 7449 SENFLTSIHILNVDAADIGEYQCKATNDVGSD------TCVGSIALK------------- 7489

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202
                            PP+F  KL  +    G+  +    I G     V W K    + +
Sbjct: 7490 ---------------APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVR 7534

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA---------------- 246
             S  + +S    +  L+   V   + G YTC + N +G     A                
Sbjct: 7535 ESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPES 7594

Query: 247  -----------ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSK 295
                       E ++ G    +  + ++ K   SD + +++   +K S L  +  A    
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKIS-FFNKVSGLKIINVAPSD- 7652

Query: 296  NCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE 355
                     S  ++   Q    ++S   S + S RT P +   +K   +  L  + V  E
Sbjct: 7653 ---------SGVYSFEVQNPVGKDSCTASLQVSDRTVPPS-FTRKLKETNGLSGSSVVME 7702

Query: 356  PRAPGLGVLSPS----GEE----RKRPAPPRPATFPTRQPGL---GSQDVVSKAANRRIP 404
             +  G   +S S    G E    RK        T       L    S D    A N    
Sbjct: 7703 CKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATN---- 7758

Query: 405  MEGQRDSAFP-------KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
            M G  + + P        F  KP   +V     V F   V G P   V+WF   + +   
Sbjct: 7759 MAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPG 7818

Query: 458  EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
            +      ED+ +  L L    T  SG Y+C  SN  G+ SC+  L ++  A       F 
Sbjct: 7819 DRCNVSLEDSVAE-LELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPA------KFV 7871

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDAL 574
              L D ++ +G+  +L+ +  GTP   +TW  NG    P Q    T     A L I  + 
Sbjct: 7872 KRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSST 7931

Query: 575  PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
             ED G Y C  ENA G+ SCSA + + E                    P F++ L  +KV
Sbjct: 7932 VEDAGQYNCYIENASGKDSCSAQILILEP-------------------PYFVKQLEPVKV 7972

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
              G   ++  Q++G P   V W     +++ +  +    R    +L   +V   D+G Y 
Sbjct: 7973 SVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYI 8032

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 754
            C+A NS GEV     LTVQE      P F  + R V  ++G  V+  CAI+G    +V W
Sbjct: 8033 CKAENSVGEVSASTFLTVQE--QKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSW 8090

Query: 755  LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             +DGK L KD+ + +    ++  TL + K     AGQY     N +G  S    L+L
Sbjct: 8091 YKDGKPL-KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146



 Score =  188 bits (478), Expect = 4e-47
 Identities = 216/961 (22%), Positives = 369/961 (38%), Gaps = 152/961 (15%)

Query: 414  PKFESKPQ-SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
            P+F  K + S+ VK+++  ++ C++ G P+ +V W+ + T ++        + D+ +  L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVA-VL 7363

Query: 473  CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
             +      DSG Y+C A NA G  S S +L+V+   +    P     LK      G D  
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK------GADVH 7417

Query: 533  LQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENAL 589
            L+C ++GTP   ++W  + + ++  +      E  +  +HI +    D G Y C A N +
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G  +C   + +               AP     P F++ LSD+  + G +V +   + G 
Sbjct: 7478 GSDTCVGSIALK--------------AP-----PRFVKKLSDISTVVGKEVQLQTTIEGA 7518

Query: 650  PPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
             P  V+W  +  EI +ES++          +L    V P + G YTC+  N AG     A
Sbjct: 7519 EPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFA 7578

Query: 709  VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 768
             L+V EP        + KP S+  + G +  + C +AG P  +  W +DGK L  D   +
Sbjct: 7579 TLSVLEPAT-----IVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDN-KY 7632

Query: 769  EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPA 826
            ++     V  L +  V P  +G Y   ++N VG+ SC  SL +   S R +P    R+  
Sbjct: 7633 KISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQV---SDRTVPPSFTRKLK 7689

Query: 827  SCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEA 886
                L G  V  +      YGS     P     W  E  G ++    K +     +T  A
Sbjct: 7690 ETNGLSGSSVVME---CKVYGS-----PPISVSWFHE--GNEISSGRKYQTTLTDNT-CA 7738

Query: 887  IRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVH 946
            +    +E+ D  D     ++T     D+                    P TV E    V 
Sbjct: 7739 LTVNMLEESDSGDY--TCIATNMAGSDECS-----------------APLTVREPPSFVQ 7779

Query: 947  SPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVL--GGKKKLPAENGSSSAETLN 1004
             P  +D   VL     + T + +  PP   +     S L  G +  +  E+  +  E  +
Sbjct: 7780 KPDPMD---VLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFD 7836

Query: 1005 AKAVES-------SKPLSNAQPSGPLKPVGNAKPAETL--------KPM-------GNAK 1042
                +S       S     A  +  L     AK  + L        KP+       G   
Sbjct: 7837 VDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPP 7896

Query: 1043 PAETLKPMG-NAKPDE--NLKSASKEELKKDVKNDV------NCKRGHAGTTDNEKRSES 1093
             + T K  G N  P +  N+ +  K  + +   + V      NC   +A   D+      
Sbjct: 7897 ISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQIL 7956

Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLC 1153
                P F ++L+ V V+ G    LQCQ++  P   + W      L+ T    +    ++ 
Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVA 8016

Query: 1154 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
            ++   +    D G Y C A+N  G+   S  +TV +                        
Sbjct: 8017 TLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE------------------------ 8052

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                                  +PP   +   D +   G  V     ++G++PI+ +W K
Sbjct: 8053 --------------------QKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYK 8092

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
              K +++S +++    +N + L I    +   G Y+    N +GS  +   L + +  +P
Sbjct: 8093 DGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNP 8152

Query: 1334 P 1334
            P
Sbjct: 8153 P 8153



 Score =  183 bits (465), Expect = 1e-45
 Identities = 200/829 (24%), Positives = 321/829 (38%), Gaps = 119/829 (14%)

Query: 24   VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
            VD       P+F    +N     GA+   E +V G     V W      I SG ++    
Sbjct: 5791 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKY---- 5846

Query: 84   GIRGTFS-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
              + TFS     L ++++   D G YTC A N +G+ +    LTV+              
Sbjct: 5847 --QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE------------- 5891

Query: 139  TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
                                 PP F  +   + V  G+   F+  I G P  +V W +G 
Sbjct: 5892 ---------------------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930

Query: 199  VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS--- 255
              L    R ++  ++ +  LE+  ++    G YTC+V N +G+AS +  L ++   +   
Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLK 5990

Query: 256  --------ANRSFVRETKATNS-----DVRKEVTNVISKES-KLDSLEAAAKSKNCSSPQ 301
                      +S + E+  T +       +K+  N+ + E   + + E     +  +S +
Sbjct: 5991 RLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTK 6050

Query: 302  RGGSPPWAANSQPQPPRE--SKLESCKDSPRTAPQ-TPVLQKTSSSITLQAARVQPEPRA 358
            R     ++   + +  R+    L S  + P    +  P+      S++LQ          
Sbjct: 6051 RDAG-QYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQC----QVAGT 6105

Query: 359  PGLGVLSPSGEERKRPAPPRPATFPTRQPGL--------GSQDVVSKA------ANRRIP 404
            P + V    G+ + RP P     F      L         S +   KA      A+ +  
Sbjct: 6106 PEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTV 6165

Query: 405  MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
               Q     P F  + +  E      V   C ++G    +V W+ +G  +R  E     +
Sbjct: 6166 FRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF 6225

Query: 465  EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
             D     L +L+     SG YSC+ASN  G  S S  L        + +P F        
Sbjct: 6226 VD-NVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTARE---PKKSPFFDIKPVSID 6281

Query: 525  VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTY 581
            VI G+    +C V G    RITW  + + I+   +   TC      L I      D G Y
Sbjct: 6282 VIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQY 6341

Query: 582  TCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-MDGSQV 640
            TC A N +G+  CSA ++V E                    P F++ L   KV   G  +
Sbjct: 6342 TCQATNDVGKDMCSAQLSVKE-------------------PPKFVKKLEASKVAKQGESI 6382

Query: 641  TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
             +  ++SG+P  +V W  N +E+ ES  ++     +   L I E   ED+G Y CEA N 
Sbjct: 6383 QLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNG 6442

Query: 701  AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 760
             G+      LTV+ P     P F  KP  V A  G  V++ C I+G P   V W++D K 
Sbjct: 6443 VGDASCSTALTVKAP-----PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQ 6497

Query: 761  LCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQV 807
            + +++  F++       +L +  ++    G+Y     N VG   CSC V
Sbjct: 6498 V-RNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSV 6545



 Score =  183 bits (464), Expect = 2e-45
 Identities = 195/836 (23%), Positives = 324/836 (38%), Gaps = 132/836 (15%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            + + E P+F+  P  L +  G    F   +RG P  +V W R  + +  G R    C I 
Sbjct: 5887 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDR----CNIY 5942

Query: 87   ---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
                   L +  +     G+YTC  +N +G    T  L     F K+             
Sbjct: 5943 FEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRL-----FVKE------------- 5984

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
                            P  F  +L    V+ G+        TG     VTW K    +  
Sbjct: 5985 ----------------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITT 6028

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA--------------------- 242
            S + ++       +LEI    + D G Y+C + N +G+                      
Sbjct: 6029 SEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPL 6088

Query: 243  ------SMSAELSIQGLDSANRSFVR-ETKATNS-DVRKEVTN-----VISKESKLDSLE 289
                  S+S +  + G      S+ + +TK   + + R   TN     V +K +  DS E
Sbjct: 6089 EAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGE 6148

Query: 290  AAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ-KTSSSITLQ 348
               K++N S         +    +  PP  S     KD  +T      L  + + S  +Q
Sbjct: 6149 YTCKAEN-SIGTASSKTVFRIQERQLPP--SFARQLKDIEQTVGLPVTLTCRLNGSAPIQ 6205

Query: 349  AARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP---- 404
                +        GVL    E  +       AT    Q  L      S +A+  +     
Sbjct: 6206 VCWYRD-------GVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASS 6258

Query: 405  ---MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461
               +  +     P F+ KP S +V   ++  F C V+G     + W  +   +R   G+ 
Sbjct: 6259 SARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIR-PGGNY 6317

Query: 462  EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521
             +     + +L +LK    DSG Y+C A+N  G+  CS  L V+        P F   L+
Sbjct: 6318 TITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKE------PPKFVKKLE 6371

Query: 522  DCAVI-EGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPE 576
               V  +G+   L+C + G+P  +++W  N   +    +Y  S   + VA L I +A  E
Sbjct: 6372 ASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINS-VALLTINEASAE 6430

Query: 577  DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
            D G Y C A N +G  SCS  +TV               AP     P+F Q  S +  + 
Sbjct: 6431 DSGDYICEAHNGVGDASCSTALTVK--------------AP-----PVFTQKPSPVGALK 6471

Query: 637  GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
            GS V +  ++SG PP EV+W+ +  +++ S+ F    +    SL I  +   D G Y C+
Sbjct: 6472 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 6531

Query: 697  AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
            A N  G       +  +EP     P F+ K    +  +G +V +   + G    +V WL+
Sbjct: 6532 ATNEVGSDTCSCSVKFKEP-----PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLK 6586

Query: 757  DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG--ECSCQVSLM 810
            D   + +++ +  +   +++ TL L   +  ++G+Y   +KN  G  ECS  ++++
Sbjct: 6587 DRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVL 6642



 Score =  176 bits (446), Expect = 2e-43
 Identities = 181/789 (22%), Positives = 290/789 (36%), Gaps = 142/789 (17%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            M +  AP        L +  G  AKF   ++  P  +  W + G+ I    +    C IR
Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIR 3505

Query: 87   GT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
             +    SL I      D G+YTC+A+N  G+   T  LTV  ++                
Sbjct: 3506 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY---------------- 3549

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
                            PP F ++   +    G+  +F C +TG P  +  W K    L P
Sbjct: 3550 ----------------PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP 3593

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
            S    +S+     +LE+  +   D GVY+C   N  G     AEL I  +D  +  F++E
Sbjct: 3594 SPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII--IDKPH--FIKE 3649

Query: 264  TKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLE 323
             +   S + K+V      E ++D               R  +  W+ + Q  PP +   +
Sbjct: 3650 LEPVQSAINKKV----HLECQVDE-------------DRKVTVTWSKDGQKLPPGKD-YK 3691

Query: 324  SCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP 383
             C +      + P+ +   S                G  V + S E          AT  
Sbjct: 3692 ICFEDKIATLEIPLAKLKDS----------------GTYVCTASNEAGSSSC---SATVT 3732

Query: 384  TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESK-PQSQEVKENQTVKFRCEVSGIPK 442
             R+P                          P F  K   S  +   ++ +  C++ G P 
Sbjct: 3733 VREP--------------------------PSFVKKVDPSYLMLPGESARLHCKLKGSPV 3766

Query: 443  PEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
             +V WF     +  +  ++ +Y       L +   +  DSG+YSC A N  G  SCS  +
Sbjct: 3767 IQVTWFKNNKEL-SESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825

Query: 503  QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RS 559
                  V++  PSF   L+   ++ G + +LQC V GT    I+W  + + I+ +   R 
Sbjct: 3826 ------VIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL 3879

Query: 560  TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSK 619
              +  +  L I      D G Y C+  N +G+  C A   + E                 
Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE----------------- 3922

Query: 620  PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
               P F++ + DL  + G  VT+   V G+ P  V W+     I+E              
Sbjct: 3923 --PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAV 3980

Query: 680  LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
            L I +V     G YTC A N AG   +   L V+EP        I +   +  + G    
Sbjct: 3981 LIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAK-----IIERAELIQVTAGDPAT 4035

Query: 740  ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
            +   +AG P     W +DG+ L   +  + +    +V  L     +   +GQY   + N 
Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPLVA-SKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNE 4094

Query: 800  VGECSCQVS 808
            VG  SC+ +
Sbjct: 4095 VGSSSCETT 4103



 Score =  172 bits (437), Expect = 2e-42
 Identities = 123/402 (30%), Positives = 180/402 (44%), Gaps = 34/402 (8%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P F  KPQSQ+V  N  V+ +  V G     + WF +   +     +  V++D  S  L 
Sbjct: 4768 PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELH-SGAARSVWKDDTSTSLE 4826

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L  A+  DSGTY C  SN  G  +   TL V+        PS   VL++     GQ    
Sbjct: 4827 LFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRN-----GQSTTF 4881

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
            +C + GTP  R++W L+G  I   +    +   G+A   I  A  E+ GTY C A N  G
Sbjct: 4882 ECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAG 4941

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
              SCS  + V E                    P F++ L  ++V+  S V +  +V+G P
Sbjct: 4942 TASCSIELKVKEP-------------------PTFIRELKPVEVVKYSDVELECEVTGTP 4982

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
            P EV WL N  EI+ S+ +    R +  +L I +  P DTG Y C   N  G       +
Sbjct: 4983 PFEVTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRV 5042

Query: 711  TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770
             ++EP     P FI K  + T  L  S      +AG P  ++ WL+D + L +D   + +
Sbjct: 5043 ALKEP-----PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVY-I 5096

Query: 771  LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
               + V TL ++ V   H+G+Y    KN  G   C   L++Q
Sbjct: 5097 SFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138



 Score =  165 bits (417), Expect = 4e-40
 Identities = 182/788 (23%), Positives = 302/788 (38%), Gaps = 136/788 (17%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            L E P+FI    N      ++A F+  V G P   +TW ++ Q +       +   +   
Sbjct: 5044 LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSV 5102

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
             +L I +V     G+YTC+A N SG  +    L V+                        
Sbjct: 5103 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE----------------------- 5139

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
                       P +   K   V V E       C + G P+ +V WLK    + PS   S
Sbjct: 5140 -----------PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFS 5188

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
            +S +N +    I  V + D G YT  V N  G +S  A L +    +   SF +  K T 
Sbjct: 5189 MSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD-QNIPPSFTK--KLTK 5245

Query: 269  SDVRKEVTNVISKESKLD-SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
             D  K + + I  E K+  SL  +A+              W  + +           C +
Sbjct: 5246 MD--KVLGSSIHMECKVSGSLPISAQ--------------WFKDGKEISTSAKYRLVCHE 5289

Query: 328  SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
               +     +  + +++ T + + V  +    G+  +           PP     P RQ 
Sbjct: 5290 RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK---------EPPSFLVKPGRQQ 5340

Query: 388  GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
             +    V  KA  +            P F+ K             F+ +V  +  P+   
Sbjct: 5341 AIPDSTVEFKAILK----------GTPPFKIK------------WFKDDVELVSGPKCFI 5378

Query: 448  FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
             LEG+                + +L L       +G Y+C  +N  G  SC+  L V   
Sbjct: 5379 GLEGS----------------TSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE- 5421

Query: 508  AVMEVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 563
                  P F   L+   +++ G    L+C + G+P  R+ W  N   +  +   R T   
Sbjct: 5422 -----PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFID 5476

Query: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 623
             VA + + +   ED G + C A+N  G  SCS  V V E           PV  S P  P
Sbjct: 5477 SVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP----------PVFSSFP--P 5524

Query: 624  IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 683
            I       ++ +  ++V++  ++SG PP EV+W  +  +++ S+ +    +    S+ I 
Sbjct: 5525 I-------VETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHIL 5577

Query: 684  EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 743
             V   D G Y C+A N  G       + ++EP     P F+SK  S+T   G+   +  +
Sbjct: 5578 NVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFVSKLNSLTVVAGEPAELQAS 5632

Query: 744  IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 803
            I G     V WL++ + + +++ +  +   E+V TL   K +P +AG+Y   +KN  G  
Sbjct: 5633 IEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMR 5692

Query: 804  SCQVSLML 811
                +LM+
Sbjct: 5693 ENMATLMV 5700



 Score =  164 bits (416), Expect = 6e-40
 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)

Query: 63    QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
             +VTW+++G+ +   G F       GT+ L I+ + E D+G+Y CE +   G  +  ++  
Sbjct: 32748 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 32807

Query: 123   VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
              +            S  K+  Q     T+  +    A E   S      P   T L    
Sbjct: 32808 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 32862

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V    + +F+ K TG P+P   W K    +    +  +SE  G   LEIH  +  D G+Y
Sbjct: 32863 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 32922

Query: 232   TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
             TC V N +G  S S +L+I+ +       V   K +       + V++E++    +  ++
Sbjct: 32923 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 32982

Query: 286   DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
                EA ++         SK   S +   S   +          +K     +  RT  +  
Sbjct: 32983 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 33042

Query: 337   VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
                 T  SI  +  R+  +    G         GV   + EE +        T   +Q  
Sbjct: 33043 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 33100

Query: 389   LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
                + +   +SK     +  +      +  S  P F S+P+SQ + E Q V F CE+SG 
Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 33160

Query: 441   PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
             P PE+ WF    P+     ++ +      + L +  A   DSG Y+  A N +GQ  CS 
Sbjct: 33161 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 33217

Query: 501   TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
             T  +  L ++E  PS   VL+        D  LQ S             + Q +Q + S 
Sbjct: 33218 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 33259

Query: 561   CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
              EA  +      A       +  ++  ++        ++S S+++ +        S   +
Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 33319

Query: 614   PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
               A  +   P      SD+ + +G  +T+    +G P PEV W   G +I  QE   FH 
Sbjct: 33320 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 33379

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             E      +L I +V  +D G YT    N  G
Sbjct: 33380 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 33410



 Score =  163 bits (413), Expect = 1e-39
 Identities = 181/791 (22%), Positives = 289/791 (36%), Gaps = 144/791 (18%)

Query: 31   EAPAFILPPRN-LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
            E P FI  P   L ++ G +  FE ++ G P+ +V+W+ +G  IT+  +  +   I G  
Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDGLA 4917

Query: 90   SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
            +  I     E+ G Y CEA N +G    ++EL V+                         
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKE------------------------ 4953

Query: 150  ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
                      PP F  +L  V V +       C++TG P  +VTWLK N  ++ S + ++
Sbjct: 4954 ----------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL 5003

Query: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269
            +++  +  L I   +  D G Y C+V N  G  S S  ++++       SF+++ + T  
Sbjct: 5004 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK----EPPSFIKKIENT-- 5057

Query: 270  DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESC 325
                  T V+   +   S  A             GSPP    W  + Q     ++   S 
Sbjct: 5058 ------TTVLKSSATFQSTVA-------------GSPPISITWLKDDQILDEDDNVYISF 5098

Query: 326  KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
             DS  T     V    S   T QA               + SG ER        A    +
Sbjct: 5099 VDSVATLQIRSVDNGHSGRYTCQAK--------------NESGVERCY------AFLLVQ 5138

Query: 386  QPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEV 445
            +P      +V KA                      +S +V E   +   C V+G P+ +V
Sbjct: 5139 EPA----QIVEKA----------------------KSVDVTEKDPMTLECVVAGTPELKV 5172

Query: 446  AWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
             W  +G  +         +E+  + +  +     +DSG Y+    N  G  SC   L   
Sbjct: 5173 KWLKDGKQIVPSRYFSMSFENNVASFR-IQSVMKQDSGQYTFKVENDFGSSSCDAYL--- 5228

Query: 506  RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCE 562
            R+    + PSF+  L     + G    ++C V G+      W  +G+ I  +   R  C 
Sbjct: 5229 RVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288

Query: 563  AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622
                 L + +   ED   YTC   N  G  +CS  +TV E                    
Sbjct: 5289 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-------------------P 5329

Query: 623  PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
            P FL      + +  S V     + G PP ++ W  +  E+           G+   L +
Sbjct: 5330 PSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNL 5389

Query: 683  QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLIS 741
              V    TG YTC   N  G      +L V EP     P F+ K   S     G S  + 
Sbjct: 5390 YSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP-----PKFVKKLEASKIVKAGDSSRLE 5444

Query: 742  CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
            C IAG P   V W R+   L   +  + +   + V  + +  +    +G +    +N  G
Sbjct: 5445 CKIAGSPEIRVVWFRNEHEL-PASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 5503

Query: 802  ECSCQVSLMLQ 812
              SC   ++++
Sbjct: 5504 STSCSTKVIVK 5514



 Score =  159 bits (402), Expect = 2e-38
 Identities = 114/408 (27%), Positives = 182/408 (44%), Gaps = 16/408 (3%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+   + Q   V+  +  +F   +SG P+P+++W+ E   +       +   D   + L 
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3297

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
            L++A   D+  Y+C A N  G  + S +L VE   V+          P+  + L+D    
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3357

Query: 527  EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
            EGQ    QC V GT + +++W    +   P ++ R T      +L I +A PED GTYT 
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416

Query: 584  LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
            +A NA+GQVS +A +++   +S         +      AP+  + +  L+V  G     T
Sbjct: 3417 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFT 3476

Query: 644  VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             ++   P     W   G EI ES+           SL I      D G YTC+A N  G 
Sbjct: 3477 CEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGS 3536

Query: 704  VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
            V   A LTV E +    P F+S+P+S+T  +G++    C + G P     W +DG AL  
Sbjct: 3537 VSCTATLTVTEAY---PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAAL-S 3592

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             + ++ +   E+   L L  +     G Y     N+ G   CQ  L++
Sbjct: 3593 PSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII 3640



 Score =  156 bits (395), Expect = 2e-37
 Identities = 172/788 (21%), Positives = 296/788 (37%), Gaps = 148/788 (18%)

Query: 29   LTEAPAFILP-PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
            +TE P F+     +  +K G +++ E ++ G PE +V W RN   + +  ++ +   I  
Sbjct: 5419 VTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDS 5477

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
               + ++ +  ED G + CEA N +G+   + ++ V+                       
Sbjct: 5478 VAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK----------------------- 5514

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                 P ++   PP   T      +K  ++    C+++G P  +V W K    L+ S + 
Sbjct: 5515 ----EPPVFSSFPPIVET------LKNAEVS-LECELSGTPPFEVVWYKDKRQLRSSKKY 5563

Query: 208  SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
             ++ KN    + I  V+  D+G Y C   N  G  +    + +                 
Sbjct: 5564 KIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKL----------------- 5606

Query: 268  NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP---PWAANSQPQPPRESKLES 324
                 KE    +SK + L  +  A +     +   G  P    W          + K E 
Sbjct: 5607 -----KEPPRFVSKLNSLTVV--AGEPAELQASIEGAQPIFVQWL---------KEKEEV 5650

Query: 325  CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384
             ++S         +    +  TLQ A+ +P      +  +   G  R+       AT   
Sbjct: 5651 IRESENIR-----ITFVENVATLQFAKAEPANAGKYICQIKNDGGMRE-----NMATLMV 5700

Query: 385  RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPE 444
             +P +    +V KA     PM                   V   +T    C+V+G P+  
Sbjct: 5701 LEPAV----IVEKAG----PM------------------TVTVGETCTLECKVAGTPELS 5734

Query: 445  VAWFLEGTPV-RRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ 503
            V W+ +G  +   Q+     Y    S  L +L    +D+GTY+    N  G+ SC+  + 
Sbjct: 5735 VEWYKDGKLLTSSQKHKFSFYNKISS--LRILSVERQDAGTYTFQVQNNVGKSSCTAVVD 5792

Query: 504  VERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW------LLNGQPIQYA 557
            V   A   V PSF+  LK+   + G   +L+C V G+    + W      +++G   Q  
Sbjct: 5793 VSDRA---VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQ-- 5847

Query: 558  RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
             +T    V  L +      D G YTC+A N  G   C A +TV E               
Sbjct: 5848 -TTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE--------------- 5891

Query: 618  SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677
                 P F++    L+V+ G  VT T  + G PP +V W     E+ + +  +     T 
Sbjct: 5892 ----PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTV 5947

Query: 678  HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
              L +  +    +G YTC   N+AG+      L V+EP       F+ +    +   G+S
Sbjct: 5948 AELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP-----AAFLKRLSDHSVEPGKS 6002

Query: 738  VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
            +++     G    +V W +DG  +   +    ++  E    L +       AGQY   ++
Sbjct: 6003 IILESTYTGTLPISVTWKKDGFNI-TTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6061

Query: 798  NRVGECSC 805
            N  G   C
Sbjct: 6062 NEAGRDVC 6069



 Score =  152 bits (384), Expect = 3e-36
 Identities = 153/659 (23%), Positives = 252/659 (38%), Gaps = 74/659 (11%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            PP+   +L  V V+ G+  RF   I+GRPQP+++W K    L    +           L 
Sbjct: 3238 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3297

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            +     +D  VYTC   N  G A+ SA LS++         V E  + + ++      +I
Sbjct: 3298 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVSPDQEMPVYPPAII 3348

Query: 280  SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVL 338
            +      + E       C          W +  +  +P R  ++   +D+ +        
Sbjct: 3349 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQ-------- 3400

Query: 339  QKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKA 398
                    L+ A   PE       V S +  +    A           P    + ++ + 
Sbjct: 3401 --------LEIAEAYPEDEGTYTFVASNAVGQVSSTA-----NLSLEAP----ESILHER 3443

Query: 399  ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE 458
              + I ME +   A P  + K +  EV      KF CE+   P     WF  G  +   +
Sbjct: 3444 IEQEIEMEMK---AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESD 3500

Query: 459  GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518
                +        L +L+ +  D G Y+C ASN  G +SC+ TL V         P+F S
Sbjct: 3501 -KCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE----AYPPTFLS 3555

Query: 519  VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI---QDALP 575
              K      G+     C+V GTPV    W  +G  +  + +   +     HI    +   
Sbjct: 3556 RPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTI 3615

Query: 576  EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
            +D G Y+C A N  G   C A + + +K                   P F++ L  ++  
Sbjct: 3616 QDRGVYSCKASNKFGADICQAELIIIDK-------------------PHFIKELEPVQSA 3656

Query: 636  DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
               +V +  QV  +    V W  +G ++   +D+         +L I     +D+GTY C
Sbjct: 3657 INKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVC 3716

Query: 696  EAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHW 754
             A N AG     A +TV+EP     P F+ K   S     G+S  + C + G P   V W
Sbjct: 3717 TASNEAGSSSCSATVTVREP-----PSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTW 3771

Query: 755  LRDGKALCK-DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             ++ K L + +T     + +E +  +   KV+   +G Y     N VG  SC   ++++
Sbjct: 3772 FKNNKELSESNTVRMYFVNSEAILDITDVKVE--DSGSYSCEAVNDVGSDSCSTEIVIK 3828



 Score =  150 bits (378), Expect = 1e-35
 Identities = 184/788 (23%), Positives = 286/788 (36%), Gaps = 141/788 (17%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
            AP F  P RN+      T + + ++ G    +V+W ++G+ I +  R+ +   + GT SL
Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRI-AFVEGTASL 4170

Query: 92   VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
             I  V   D G +TC ATN  G++  +  L V+                           
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204

Query: 152  RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
                    PP F TK G   V  G          G     + W KGN  L       +++
Sbjct: 4205 --------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITK 4256

Query: 212  KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
            +     LE++ V   D G YTC V N +G    SA L ++       +FV + + +    
Sbjct: 4257 EALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK----EPATFVEKLEPSQLLK 4312

Query: 272  RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKD 327
            + + T +  K +                    G+PP    W AN      RE K ES K 
Sbjct: 4313 KGDATQLACKVT--------------------GTPPIKITWFAND-----REIK-ESSKH 4346

Query: 328  SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
                   T VL+ T   I                     SGE                Q 
Sbjct: 4347 RMSFVESTAVLRLTDVGI-------------------EDSGE-----------YMCEAQN 4376

Query: 388  GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
              GS    S    +  P        F K E KP   EV +   V    EV+G P  E+ W
Sbjct: 4377 EAGSDHCSSIVIVKESPY-------FTK-EFKP--IEVLKEYDVMLLAEVAGTPPFEITW 4426

Query: 448  FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
            F + T + R     + +       L +LK    D+G Y C  +N  G   CS      R+
Sbjct: 4427 FKDNT-ILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS-----ARV 4480

Query: 508  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAG 564
             + E  PSF   ++  + + G     Q +++G+    +TWL +   I      R T E  
Sbjct: 4481 TLRE-PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 4539

Query: 565  VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
            VA L++     +  G Y C A+N  G   CSA ++V                  K  A I
Sbjct: 4540 VASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSV------------------KEPATI 4581

Query: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
              + +S + V  G   T+ V+ SG       W  +G E+     +      T   L I  
Sbjct: 4582 TEEAVS-IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIIS 4640

Query: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
               +D+G YT E  N  G    +A + V +      P F  K + + +  G  + + C +
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDLI--IPPSFTKKLKKMDSIKGSFIDLECIV 4698

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
            AG    ++ W +D + +     +     +   F L + +++   +G Y     N+ G   
Sbjct: 4699 AGSHPISIQWFKDDQEISASEKYKFSFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQ 4757

Query: 805  CQVSLMLQ 812
            C   L ++
Sbjct: 4758 CSGHLTVK 4765



 Score =  149 bits (375), Expect = 3e-35
 Identities = 114/402 (28%), Positives = 173/402 (43%), Gaps = 34/402 (8%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P FE  P S EV    ++ F   + G P  +V WF     +   E      ED  +  L 
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTE-LE 6892

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L + +  +SG YSC  +N  G  SC+  L V+  A      +F   L D +V  G   VL
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA------TFVKRLADFSVETGSPIVL 6946

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALPEDHGTYTCLAENAL 589
            + +  GTP   ++W+ +   I  +   C   + E    L I ++  ED+  Y+CL EN  
Sbjct: 6947 EATYTGTPPISVSWIKDEYLISQSER-CSITMTEKSTILEILESTIEDYAQYSCLIENEA 7005

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            GQ  C A V+V E                    P F++ L  ++ + G   T+  +V G 
Sbjct: 7006 GQDICEALVSVLEP-------------------PYFIEPLEHVEAVIGEPATLQCKVDGT 7046

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P   + W     +++ +  +  + +    SL I +V   D G Y+C+A NS G V + AV
Sbjct: 7047 PEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAV 7106

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            L ++       P+F  K + V  +LG  V   C I G     V W +DG  L KD  + +
Sbjct: 7107 LVIKARK--LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG-VLLKDDANLQ 7163

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
                 +V TL + +    H GQY     N +G  S    L+L
Sbjct: 7164 TSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLIL 7205



 Score =  143 bits (360), Expect = 2e-33
 Identities = 101/400 (25%), Positives = 178/400 (44%), Gaps = 35/400 (8%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P F+ KP S ++   ++  F+C V+G    ++ W  +   +R   G+ ++     +  L 
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIR-PGGNYKMTLVENTATLT 7270

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV- 532
            +LK    D+G Y+C ASN  G+ SCS  L V+        P F   L+   +++  +F  
Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE------PPRFIKKLEPSRIVKQDEFTR 7324

Query: 533  LQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
             +C + G+P  ++ W  +   IQ +   R +    VA L + +   ED G YTC A NA 
Sbjct: 7325 YECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAA 7384

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G  S S  + V E                    PIF +    ++ + G+ V +  ++ G 
Sbjct: 7385 GSASSSTSLKVKEP-------------------PIFRKKPHPIETLKGADVHLECELQGT 7425

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            PP  V W  +  E++  + +         S+ I  V   D G Y C+A N  G       
Sbjct: 7426 PPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGS 7485

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            + ++ P     P F+ K   ++  +G+ V +   I G    +V W +D   + +++ +  
Sbjct: 7486 IALKAP-----PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIW 7540

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
            +  +E++ TL   +V+P +AG+Y   +KN  G   C  +L
Sbjct: 7541 ISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATL 7580



 Score =  141 bits (356), Expect = 5e-33
 Identities = 118/449 (26%), Positives = 181/449 (40%), Gaps = 52/449 (11%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P F S+P+S      +  KF C V+G P  E  W  +G  +     +  + +    H L 
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSP-NWRISDAENKHILE 3609

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L     +D G YSC ASN  G   C    Q E + + +  P F   L+       +   L
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADIC----QAELIIIDK--PHFIKELEPVQSAINKKVHL 3663

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
            +C V       +TW  +GQ +   +      E  +A L I  A  +D GTY C A N  G
Sbjct: 3664 ECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAG 3723

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
              SCSA VTV E  S     ++  V PS    P             G    +  ++ G+P
Sbjct: 3724 SSSCSATVTVREPPS-----FVKKVDPSYLMLP-------------GESARLHCKLKGSP 3765

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
              +V W  N  E+ ES         ++  L I +V  ED+G+Y+CEA N  G       +
Sbjct: 3766 VIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEI 3825

Query: 711  TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770
             ++EP     P FI          G + L+ C ++G     + W +D K + + +  + +
Sbjct: 3826 VIKEP-----PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI-RSSKKYRL 3879

Query: 771  LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML------------------Q 812
               + +  L +        G+YE ++ N VG+C C  + +L                  Q
Sbjct: 3880 FSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQ 3939

Query: 813  NSSARALPRGREPASCEDLCGGGVGADGG 841
              + +A  RG EP S   + G  V  + G
Sbjct: 3940 TVTLQAAVRGSEPISVTWMKGQEVIREDG 3968



 Score =  140 bits (353), Expect = 1e-32
 Identities = 165/790 (20%), Positives = 277/790 (35%), Gaps = 139/790 (17%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            + + E P FI   + + + + +  + E  V G P  +VTW +N + I S  ++ L   + 
Sbjct: 4949 LKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV- 5007

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
              F+L I      D G+Y C  +N  G+   +  + ++                      
Sbjct: 5008 SVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE--------------------- 5046

Query: 147  PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
                         PP F  K+            F   + G P   +TWLK +  L     
Sbjct: 5047 -------------PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 5093

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266
            V +S  + +  L+I  V+    G YTC   N SG     A L +Q               
Sbjct: 5094 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ--------------- 5138

Query: 267  TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326
                   E   ++ K   +D  E    +  C      G+P            E K++  K
Sbjct: 5139 -------EPAQIVEKAKSVDVTEKDPMTLECVV---AGTP------------ELKVKWLK 5176

Query: 327  DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
            D  +  P         +++   + R+Q   +         SG+           TF    
Sbjct: 5177 DGKQIVPSRYFSMSFENNVA--SFRIQSVMK-------QDSGQ----------YTFKVEN 5217

Query: 387  P-GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEV 445
              G  S D   +  ++ IP         P F  K    +     ++   C+VSG      
Sbjct: 5218 DFGSSSCDAYLRVLDQNIP---------PSFTKKLTKMDKVLGSSIHMECKVSGSLPISA 5268

Query: 446  AWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
             WF +G  +        V  +  S  L +      D+  Y+C  SN  G  +CS  L V+
Sbjct: 5269 QWFKDGKEISTSAKYRLVCHER-SVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327

Query: 506  RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CE 562
                  V P     + D  V        +  ++GTP  +I W  +   +          E
Sbjct: 5328 EPPSFLVKPGRQQAIPDSTV------EFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLE 5381

Query: 563  AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622
               + L++        G YTC   N +G  SC+  + V E                    
Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE-------------------P 5422

Query: 623  PIFLQGLSDLKVMD-GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
            P F++ L   K++  G    +  +++G+P   V+W  N +E+  S+ +      +   + 
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482

Query: 682  IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
            +  +  ED+G + CEA N AG       + V+EP     P F S P  V       V + 
Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP-----PVFSSFPPIVETLKNAEVSLE 5537

Query: 742  CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
            C ++G P   V W +D + L + +  +++       ++ +  V     G+Y    +N VG
Sbjct: 5538 CELSGTPPFEVVWYKDKRQL-RSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVG 5596

Query: 802  E--CSCQVSL 809
               C C V L
Sbjct: 5597 SDTCVCTVKL 5606



 Score =  137 bits (345), Expect = 1e-31
 Identities = 113/395 (28%), Positives = 167/395 (42%), Gaps = 50/395 (12%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS---GTYSCTASN 491
            C+V+G     VAWF E T +     S   Y+   S  +C L+  + DS   G Y+C A+N
Sbjct: 5821 CKVAGSSPISVAWFHEKTKIV----SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAAN 5876

Query: 492  AQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551
              G   C   L V+        PSF    +   V+ G++      +RGTP  ++ W    
Sbjct: 5877 VAGSDECRAVLTVQE------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930

Query: 552  QPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
            + +          E  VAEL + +      G YTC+  N  GQ SC+  + V E      
Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE------ 5984

Query: 609  SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668
                       P A  FL+ LSD  V  G  + +    +G  P  V W  +G  I  SE 
Sbjct: 5985 -----------PAA--FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEK 6031

Query: 669  FHFEQRGTQHSLCIQEVF---PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             +     T    CI E+      D G Y+CE  N AG     A+++  EP     P+F++
Sbjct: 6032 CNIV---TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP-----PYFVT 6083

Query: 726  KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
            +   + A++G SV + C +AG P  TV W + G    + T  +      +V TLV  KV 
Sbjct: 6084 ELEPLEAAVGDSVSLQCQVAGTPEITVSWYK-GDTKLRPTPEYRTYFTNNVATLVFNKVN 6142

Query: 786  PWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
               +G+Y    +N +G  S +    +Q    R LP
Sbjct: 6143 INDSGEYTCKAENSIGTASSKTVFRIQE---RQLP 6174



 Score =  136 bits (343), Expect = 2e-31
 Identities = 107/403 (26%), Positives = 170/403 (42%), Gaps = 30/403 (7%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P F ++ +  E     +V  +C+V+G P+  V+W+ +G    R       Y       L 
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWY-KGDTKLRPTPEYRTYFTNNVATLV 6137

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
              K    DSG Y+C A N+ G  S     +++     ++ PSF+  LKD     G    L
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTASSKTVFRIQE---RQLPPSFARQLKDIEQTVGLPVTL 6194

Query: 534  QCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590
             C + G+   ++ W  +G  +   +  +++    VA L I        G Y+C A N LG
Sbjct: 6195 TCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLG 6254

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
              S SA +T  E K S       P    KP +         + V+ G        V+G  
Sbjct: 6255 TASSSARLTAREPKKS-------PFFDIKPVS---------IDVIAGESADFECHVTGAQ 6298

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
            P  + W  +  EI+   ++     G    L I +V   D+G YTC+A N  G+    A L
Sbjct: 6299 PMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358

Query: 711  TVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            +V+EP     P F+ K   S  A  G+S+ + C I+G P   V W R+   L  ++  + 
Sbjct: 6359 SVKEP-----PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSEL-HESWKYN 6412

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
            +     V  L + +     +G Y     N VG+ SC  +L ++
Sbjct: 6413 MSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455



 Score =  136 bits (342), Expect = 2e-31
 Identities = 119/403 (29%), Positives = 165/403 (40%), Gaps = 33/403 (8%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+F  K           V+ R  V G     V W  +   V R+  +  +        L 
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQ 6610

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L      +SG Y C   N  G   CS  L V   A +   P      +   V  G  F L
Sbjct: 6611 LGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP------EPMTVTTGNPFAL 6664

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
            +C V GTP     W  +G+ +        T    VA L I  A   D G Y+   +N++G
Sbjct: 6665 ECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVG 6724

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
            + +C+  V+VH       S+ ++P        P F++ L D+  + G+ V +  +VSG+ 
Sbjct: 6725 KSNCT--VSVHV------SDRIVP--------PSFIRKLKDVNAILGASVVLECRVSGSA 6768

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
            P  V W  +GNEI               +L +  + P DTG YTC A N AG     AVL
Sbjct: 6769 PISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVL 6828

Query: 711  TVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV 770
            TVQEP     P F   P SV    G S+  +  I G P   V W +  + L    G    
Sbjct: 6829 TVQEP-----PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELV--PGESCN 6881

Query: 771  LQNEDVFT-LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
            +  ED  T L L +VQP  +G Y  L+ N  G  SC   L ++
Sbjct: 6882 ISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924



 Score =  134 bits (336), Expect = 1e-30
 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)

Query: 396   SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
             S    +  P   +  S+ P   +  Q   V  +   KF  + +G P+P   W  +G  + 
Sbjct: 32834 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 32893

Query: 456   RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
              Q G  ++ ED G  +L + K  T DSG Y+CT  N+ G +S S  L ++          
Sbjct: 32894 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 32942

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
                 +KD    E Q    Q +   TP  +   ++  +  Q A  + E  ++E   Q+ L 
Sbjct: 32943 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 32994

Query: 576   -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
              ++  +   ++E      + S   + VHE+  K+S+ SE +   A  K  +       + 
Sbjct: 32995 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 33047

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + + +G ++ +   ++G    +V W+ NG E+  SE++ +   G+  +L I++    D G
Sbjct: 33048 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 33105

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
               TC +    G V+ Q  LT+ +      P FIS+PRS   + GQ+VL +C I+G+P P 
Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 33164

Query: 752   VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             + W ++   +   + +  + ++ +V++L ++      +G+Y I  KN  G+CS   SLM+
Sbjct: 33165 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223

Query: 812   QNSSARALPRGREPA 826
                    LP   EP+
Sbjct: 33224 -------LPLVEEPS 33231



 Score =  130 bits (327), Expect = 1e-29
 Identities = 102/386 (26%), Positives = 168/386 (43%), Gaps = 33/386 (8%)

Query: 431  VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
            V F C ++G    +V+W+ +G  + + + +++         L +L+      G Y+C+AS
Sbjct: 7133 VAFECRINGSEPLQVSWYKDGV-LLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSAS 7191

Query: 491  NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 550
            N  G  S S  L    L+  EV P F        +  G+    +C V GT   +ITW  +
Sbjct: 7192 NPLGTASSSAKLI---LSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKD 7248

Query: 551  GQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
             + I+     + T     A L +      D G YTC A N  G+ SCSA + V E     
Sbjct: 7249 NREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEP---- 7304

Query: 608  KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM-TVQVSGNPPPEVIWLHNGNEIQES 666
                           P F++ L   +++   + T    ++ G+P  +V+W  +  EIQES
Sbjct: 7305 ---------------PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQES 7349

Query: 667  EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 726
              F      +   L +  +  ED+G YTCEA N+AG   +   L V+EP     P F  K
Sbjct: 7350 SKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP-----PIFRKK 7404

Query: 727  PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQP 786
            P  +    G  V + C + G P   V W +D + L +    ++++    + ++ +  V  
Sbjct: 7405 PHPIETLKGADVHLECELQGTPPFHVSWYKDKREL-RSGKKYKIMSENFLTSIHILNVDA 7463

Query: 787  WHAGQYEILLKNRVGECSCQVSLMLQ 812
               G+Y+    N VG  +C  S+ L+
Sbjct: 7464 ADIGEYQCKATNDVGSDTCVGSIALK 7489



 Score =  129 bits (325), Expect = 2e-29
 Identities = 105/407 (25%), Positives = 168/407 (41%), Gaps = 33/407 (8%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+F SK  S  V   +  + +  + G     V W  E   V R+  +I +        L 
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQ 5669

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQV-ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
              KA   ++G Y C   N  G      TL V E   ++E A   +       V  G+   
Sbjct: 5670 FAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMT-------VTVGETCT 5722

Query: 533  LQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
            L+C V GTP   + W  +G+ +   Q  + +    ++ L I     +D GTYT   +N +
Sbjct: 5723 LECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 5782

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G+ SC+A V V ++                   P F + L +   + G+   +  +V+G+
Sbjct: 5783 GKSSCTAVVDVSDRA----------------VPPSFTRRLKNTGGVLGASCILECKVAGS 5826

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
             P  V W H   +I     +         +L +  +   D G YTC A N AG    +AV
Sbjct: 5827 SPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAV 5886

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            LTVQEP     P F+ +P  +    G++V  +  I G P   V+W R  + L K      
Sbjct: 5887 LTVQEP-----PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCN 5940

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
            +   + V  L L  +    +G+Y  ++ N  G+ SC   L ++  +A
Sbjct: 5941 IYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAA 5987



 Score =  125 bits (314), Expect = 4e-28
 Identities = 107/395 (27%), Positives = 171/395 (43%), Gaps = 37/395 (9%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKARTRDSG 483
            V+    +      +G P   V+W  +   + + E  SI + E   S  L +L++   D  
Sbjct: 6938 VETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEK--STILEILESTIEDYA 6995

Query: 484  TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
             YSC   N  GQ  C      E L  +   P F   L+    + G+   LQC V GTP  
Sbjct: 6996 QYSCLIENEAGQDIC------EALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEI 7049

Query: 544  RITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            RI+W      ++ A   +   +  VA L I      D G Y+C A+N++G V+ SA + +
Sbjct: 7050 RISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVI 7109

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
              +K        LP        P F + L D+    G  V    +++G+ P +V W  +G
Sbjct: 7110 KARK--------LP--------PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG 7153

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPED---TGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
              +++  +    Q    H++   ++   D    G Y C A N  G   + A L + E H+
Sbjct: 7154 VLLKDDANL---QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSE-HE 7209

Query: 718  GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
               P+F  KP SV  +LG+S    C + G     + W +D + + +  G++++   E+  
Sbjct: 7210 -VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREI-RPGGNYKMTLVENTA 7267

Query: 778  TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
            TL + KV    AGQY     N  G+ SC   L +Q
Sbjct: 7268 TLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302



 Score =  122 bits (306), Expect = 3e-27
 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G  + ++  I G PFP   W ++G+ + K      +  +E    LV+K+     +G Y++
Sbjct: 30151 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 30207

Query: 795   LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
             +L+N+ G+ +  + + +  S     P G  P   +D+    V       AD GG+D  G 
Sbjct: 30208 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 30263

Query: 849   LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
             +          W   +    VRG        +++ E   R     Q      L  +  V+
Sbjct: 30264 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 30321

Query: 907   TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
              KT L+  +    P E +D   +       +   +   +V +   ++ +     K    +
Sbjct: 30322 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 30380

Query: 964   KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
             KT +   +       PD       + ++ A+N    +ET  A + V    P       G 
Sbjct: 30381 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 30436

Query: 1023  LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
             L+ +  +K + TL   KP     K             D   K ++KE +K          
Sbjct: 30437 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 30496

Query: 1071  ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
                        +N+    R    T  + K   + G AP  +++++DV    G+   L CQ
Sbjct: 30497 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 30555

Query: 1121  VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
             +   P   I W   GK L  ++   +S +G   ++++     ED G+Y C+A N+ G+ E
Sbjct: 30556 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 30615

Query: 1181  CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
              S ++ +   P                                    P  P K       
Sbjct: 30616 TSSKLLLQATPQFH---------------------------------PGYPLK------- 30635

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
                 E      G ++ L     G      TW   +K +Q SE++ +EN+E+ + L +   
Sbjct: 30636 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 30691

Query: 1300  ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
              R+ H G Y + + N  G+  A +++ + DKPD P G      +  +S  +SW   + DG
Sbjct: 30692 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 30751

Query: 1360  GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GS + +Y +E  ++     W+ +++  S T+  + +L  +  Y FRV A N +G S+P +
Sbjct: 30752 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 30811

Query: 1418  ESELTTVGEKPEEP 1431
              S +  +    E+P
Sbjct: 30812 VSSVVIIKSPFEKP 30825



 Score =  121 bits (303), Expect = 7e-27
 Identities = 105/406 (25%), Positives = 179/406 (44%), Gaps = 37/406 (9%)

Query: 409  RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAG 468
            RD A P F    ++ +   N T +  C+++G     V+WF +G  +   +     + + G
Sbjct: 4109 RDIA-PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVE-G 4166

Query: 469  SHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEG 528
            +  L +++    D+G ++C A+N+ G    S  L      +++  PSF +      V+ G
Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL------IVQEPPSFVTKPGSKDVLPG 4220

Query: 529  QDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLA 585
                L+ + +G+    I W    + +    S   T EA  + L +      D GTYTC  
Sbjct: 4221 SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKV 4280

Query: 586  ENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQ 645
             N  G V CSA + V E  +     ++  + PS+            LK  D +Q  +  +
Sbjct: 4281 SNVAGGVECSANLFVKEPAT-----FVEKLEPSQL-----------LKKGDATQ--LACK 4322

Query: 646  VSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705
            V+G PP ++ W  N  EI+ES         +   L + +V  ED+G Y CEA N AG   
Sbjct: 4323 VTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDH 4382

Query: 706  TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
              +++ V+E      P+F  + + +       V++   +AG P   + W +D   L    
Sbjct: 4383 CSSIVIVKE-----SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGR 4437

Query: 766  GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809
             +   +Q+  V   +LK V    AG+Y+  + N VG   CS +V+L
Sbjct: 4438 KYKTFIQDHLVSLQILKFVAA-DAGEYQCRVTNEVGSSICSARVTL 4482



 Score =  118 bits (295), Expect = 6e-26
 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)

Query: 621  TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
            T P  + GL ++ V++G  VT+   +SG P P V W     +I+ S DF    +     L
Sbjct: 941  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000

Query: 681  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
             I+E F ED+G +TC A N AG V T   L VQ                           
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060

Query: 715  ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
                           P +   P+FI+KP       G SV+  C + G+P P V+W + G 
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120

Query: 760  ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             L   TG+ ++V  N+      LV+       AG+Y I+++N+ GE S   SL L+ +  
Sbjct: 1121 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177

Query: 817  RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
              L + ++    +      V        + G   PG+  +  +   E+E     + + K 
Sbjct: 1178 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1232

Query: 876  RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
             V  R + E+    QE     F + L K++     KT  E+ L+E   E+M    +    
Sbjct: 1233 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1288

Query: 933  VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
            V+    S  + ++ + + ++   V      S  P+P        +++   +    DF   
Sbjct: 1289 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344

Query: 982  -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
             R+ L     LP + G  +A   N K         NA  SG     P  P+G      TL
Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1396

Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
            +P+   +   +L P   ++    +  A     +         +       +    S+ + 
Sbjct: 1397 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1453

Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
               P F  K       EG+      +V   P     W  +G+ +    T  +++ ++G+ 
Sbjct: 1454 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1513

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
             S+ I  A P D G +  VA+N AG++  S  +TV+                        
Sbjct: 1514 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1550

Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
                                +  + P  ++  ++  ++ G  +E+  + TG       W+
Sbjct: 1551 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1590

Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
            K    I   ++  +++E ++  + L I +   +    YT    NK G  + + +VN+ V 
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650

Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
              +P+P      P GT  A +I +  L
Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPEL 1677



 Score =  117 bits (294), Expect = 8e-26
 Identities = 105/405 (25%), Positives = 166/405 (40%), Gaps = 38/405 (9%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED-AGSHYL 472
            P F  K +S       T  F+  + G     V W  +   +   +     +E+   S YL
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545

Query: 473  CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA-VMEVAPSFSSVLKDCAVIEGQDF 531
              ++ +    G Y C A N  G   CS  L V+  A + E A S         V +G   
Sbjct: 4546 SGIEVK--HDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSID-------VTQGDPA 4596

Query: 532  VLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
             LQ    GT      W  +GQ +    +Y  S  +  V+ L I     +D G YT   +N
Sbjct: 4597 TLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDT-VSILKIISTEKKDSGEYTFEVQN 4655

Query: 588  ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
             +G+ SC A + V         + ++P        P F + L  +  + GS + +   V+
Sbjct: 4656 DVGRSSCKARINV--------LDLIIP--------PSFTKKLKKMDSIKGSFIDLECIVA 4699

Query: 648  GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
            G+ P  + W  +  EI  SE + F        L I ++   D+GTYTC A N AG  +  
Sbjct: 4700 GSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS 4759

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
              LTV+EP     P+F+ KP+S   +    V +   + G    T+ W +D K L      
Sbjct: 4760 GHLTVKEP-----PYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAAR 4814

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              V +++   +L L   +   +G Y   L N VG  + + +L ++
Sbjct: 4815 -SVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858



 Score =  115 bits (289), Expect = 3e-25
 Identities = 104/403 (25%), Positives = 159/403 (39%), Gaps = 34/403 (8%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P F  K         QTV  +  V G     V W ++G  V R++G I++    G   L 
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFSNGVAVLI 3982

Query: 474  LLKARTRDSGTYSCTASNAQG-QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
            +   +    G Y+C A N  G Q S    +  E   ++E A           V  G    
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQ-------VTAGDPAT 4035

Query: 533  LQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
            L+ +V GTP  +  W  +G+P+  +   R + +  VA+L    A   D G YT    N +
Sbjct: 4036 LEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 4095

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G  SC    TV ++                  AP F + L ++  +      +  +++G+
Sbjct: 4096 GSSSCETTFTVLDRD----------------IAPFFTKPLRNVDSVVNGTCRLDCKIAGS 4139

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
             P  V W  +G EI  S+ +         SL I  V   D G +TC A NS G   +   
Sbjct: 4140 LPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGA 4199

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            L VQEP     P F++KP S     G +V +     G    T+ W +  K L    G   
Sbjct: 4200 LIVQEP-----PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSG-GSCY 4253

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
            + +     +L L  V+   +G Y   + N  G   C  +L ++
Sbjct: 4254 ITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296



 Score =  115 bits (288), Expect = 4e-25
 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
             + E Q +  +  ++G    +V W L G  +   E     Y  +GS     +K A  RD G
Sbjct: 33050 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 33105

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
               +C +   +G + C + L + +   +  AP+F S  +   + EGQ+ +  C + G P P
Sbjct: 33106 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 33163

Query: 544   RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              I W  N  PI  + +        V  L I++A   D G YT  A+N  GQ S +A + V
Sbjct: 33164 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223

Query: 601   HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                         LP+   +P+  + L+   D   + GS  + +VQ+S +         + 
Sbjct: 33224 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 33269

Query: 661   NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
             +      +  F     Q    +QE F E + +      N   ++ +     ++    G  
Sbjct: 33270 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 33328

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
             P   + P  ++   G+ + ++CA  G+P P V W   G+ +  ++ G F +   +D+ TL
Sbjct: 33329 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 33388

Query: 780   VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
             ++  VQ    G Y + L N  G  S  V++ +++
Sbjct: 33389 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 33422



 Score =  115 bits (287), Expect = 5e-25
 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)

Query: 163  FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
            F +++    + EG    F CK++G P P++ W K         R+   E+  M  L+   
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1343

Query: 223  VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
                             G+AS+   + +   +    +F    K           N I   
Sbjct: 1344 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1376

Query: 283  SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
             KL  +E AA           G+P +    +P     S++ S   SPR+  ++P+     
Sbjct: 1377 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1415

Query: 343  SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
                    R+ P   +P           R  PA   PA      PG   ++       R 
Sbjct: 1416 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1454

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
                       P F  KP S +  E QT +F  +V G P PE  WF +G  +        
Sbjct: 1455 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1505

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V ++ G+  L ++ A   DSG ++  A N  G+ S S  L VE +   +V P F   LK+
Sbjct: 1506 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1564

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
              + EG    ++    G P P I WL N     P +Y +   E   G A L I   + +D
Sbjct: 1565 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1624

Query: 578  HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
               YT  A N  G+    C   V V   +   + + ++P          AP         
Sbjct: 1625 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1684

Query: 618  -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
                          K   P F + L+ L++          +++  G+P   V WLH+G  
Sbjct: 1685 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
            ++ +            SL     +  D+G  TC A N  G   T A L V++        
Sbjct: 1745 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1804

Query: 715  ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
                               H+G             +P  +  P  V    G++    C +
Sbjct: 1805 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1864

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
             G P P V+W  +G+ L + +  F V + + +  L +   + +  G+ ++  +N  G   
Sbjct: 1865 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1922

Query: 805  CQVSLMLQNSS--ARALPRGREP 825
             +V L +Q        L R  EP
Sbjct: 1923 HKVKLEIQQREDFRSVLRRAPEP 1945



 Score =  113 bits (282), Expect = 2e-24
 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             +K S RK E L     +   AP     +   +V  G      + V   P  EV W HNG 
Sbjct: 32353 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 32412

Query: 662   EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
             E+QES                 D H +  GT  ++C                        
Sbjct: 32413 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 32472

Query: 683   ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
                      + VFPE T T              EA +S  EV++Q   T +      H  
Sbjct: 32473 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 32532

Query: 719   TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
             +                              ++KPRS+T   G+S   SC   G+P PTV
Sbjct: 32533 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              WLR G+ L     H +V   +   T  +  VQ    G Y ++++N  G+   + +L +Q
Sbjct: 32593 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651

Query: 813   NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
              +                        + ++  R + P                 +++   
Sbjct: 32652 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 32711

Query: 849   LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
             L    P +   +L+ E  +++          VL+ +  T     + +++    Q  +   
Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771

Query: 901   LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
                ++    L+E D    + EI  E    + NLQ   +  K++ E+  K+   ++ D + 
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831

Query: 955   --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
               S + +K   K P P    P                          P+P    T D ++
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891

Query: 984   VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
             +  GGK KL  + G                            SS+  L  KA++ ++   
Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 32951

Query: 1016  -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
              + Q +  + P   A   E +     A  +E +K M  AK  E L   + ASK    EE+
Sbjct: 32952 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 33008

Query: 1068  KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
             KK     +     H   T   + SE   T    K     + + EG++L+L+  ++     
Sbjct: 33009 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 33066

Query: 1128  TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
              + W LNG  L  ++       GS  +++I++A   D G+  C++K   G  +C   +T+
Sbjct: 33067 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126

Query: 1188  DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
                       + E+                SDA                 P  I  P  Q
Sbjct: 33127 ----------SKEL----------------SDA-----------------PAFISQPRSQ 33143

Query: 1248  KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
              +  G++V    +++G       W K    I  S ++ +  S N   L I  A     G 
Sbjct: 33144 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 33203

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+  +N  G   A  +L V+   + P+          +SL  S+   S    ++ Q  S
Sbjct: 33204 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 33263

Query: 1368  IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
                + S++ +   +   +  S + Q +    E    + + +  G S  +Q     S++  
Sbjct: 33264 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 33321

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEV 1447
              G +   PK E   SD    E +V
Sbjct: 33322 AGIRGIPPKIEALPSDISIDEGKV 33345



 Score =  112 bits (279), Expect = 4e-24
 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
            +N  I EG    F  ++ GYP P++ W+++G+ I  G R+ +D    G  SL I  V  E
Sbjct: 1298 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1357

Query: 100  DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
            D G YT  A+N  G    + +L VE   A  LG P    TL      R  +P   +R  I
Sbjct: 1358 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1415

Query: 156  WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
                                                     P F  K       EGQ  R
Sbjct: 1416 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1475

Query: 180  FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
            F  K+ GRP P+  W   G   +       V +++G Q L I      D G +T +  N 
Sbjct: 1476 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1535

Query: 239  SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
            +G++S+S  L+++ ++      FV + K  N          I + S+L+    A  + N 
Sbjct: 1536 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1584

Query: 298  SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
                      W  NS    P    + ++E  K        + V Q               
Sbjct: 1585 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1638

Query: 340  -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
              T   + ++    +PEP      ++ P G  R K  A P   P      Q      D+ 
Sbjct: 1639 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
             K   ++           P F+ K  S  +K      F C ++  G P   V W  +G P
Sbjct: 1696 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1744

Query: 454  VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
            +      + +  + G   L    A +RDSG  +C A+N  G    S TL           
Sbjct: 1745 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1803

Query: 503  -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
                       ++E L  M    + + V  D                 V+EG+    +C 
Sbjct: 1804 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1863

Query: 537  VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
            V G P P++ W LNGQ I+ ++       G+  L I D    D G     AEN  G +  
Sbjct: 1864 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1923

Query: 595  SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               + + +++  R    +L  AP  +P   +   G    +V    +   T +       E
Sbjct: 1924 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1975

Query: 654  VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
            V+ L     I      +ESE+    F++R  +            S    E + E      
Sbjct: 1976 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 2035

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
             E  +   E+  +    + E    T P F                  + +S T   G   
Sbjct: 2036 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2095

Query: 739  LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
                 + G P P   W ++G  + +    +     ++V  LV++ V    +    +   N
Sbjct: 2096 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2155

Query: 799  RVGECSCQVSLMLQ 812
              GE S    L++Q
Sbjct: 2156 IAGETSSHAFLLVQ 2169



 Score =  111 bits (278), Expect = 6e-24
 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +PP+I+  PE   ++AG+ + +   V G    TC W K   ++  S H+ V  +++ S L
Sbjct: 18898 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 18956

Query: 1296  TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
              I    ++  G Y+L  EN  G+   ++ + V+D P PP      SDI + + +LSW+  
Sbjct: 18957 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 19016

Query: 1356  SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
               DGGS + +Y +E  D +   W   LA+   TS  V  L+P  EY FRVRA N +G SE
Sbjct: 19017 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 19076

Query: 1415  PSQESELTTVGE--KPEEPKD 1433
             P    ++        P EPK+
Sbjct: 19077 PLTSPKMVAQFPFGVPSEPKN 19097



 Score =  110 bits (275), Expect = 1e-23
 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)

Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
           AP+F+  L+   V+EG     +  + G PVP ++W  +GQ I  +     + +   G A+
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
           L I      + G Y+  A N  GQ + +A + V       K+E     AP     P F+Q
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108

Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
            L  + V  GSQV + V+V+G P P V +  +G EIQ S DF   Q G  +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168

Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
           ED+GTY+  A NS G   + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194



 Score =  109 bits (272), Expect = 3e-23
 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)

Query: 30  TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
           T+AP F  P +++ + EG+TA FE  + G+P P+V+W R+GQ I++        G++ +F
Sbjct: 3   TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58

Query: 90  S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
           S     L I AV + + G+Y+ +ATNGSG    T EL V+   A                
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102

Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
                          PP F  +L  + V++G   R   ++TG P P V + +    +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147

Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
               +S++  +  L I     +D G Y+    N  G+A+ +AEL +QG            
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207

Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
           + +A  S  R+T+     +   +  ++ + E  +D   AA +     +P R   PP   +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263

Query: 312 SQPQPP 317
             P PP
Sbjct: 264 RSPTPP 269



 Score =  109 bits (272), Expect = 3e-23
 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG  +EL   VTG      TW K    +++ + + +EN    S +TI+ +++   G Y
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 13761

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              +   N  G   A V + V+DKP PPA     +D+ + S  L+W     DGGS + +Y +
Sbjct: 13762 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 13820

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
             E   + ++ W +L +T + T+F    L+P+ EY FRV A N+YG  EP Q S +T   + 
Sbjct: 13821 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 13880

Query: 1427  KPEEPKDEVEVSD 1439
              P  P   +E SD
Sbjct: 13881 DPPGPPTRLEPSD 13893



 Score =  105 bits (262), Expect = 4e-22
 Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%)

Query: 415  KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            +F    +  +V E +   F CEVS  P   V W  +   ++  +  I++ ++   H L +
Sbjct: 3059 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3116

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
               R  D+G Y+  A            +   +L V        S+ K+  VIE Q  V++
Sbjct: 3117 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3167

Query: 535  CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
              V    V    W  +G  I +      +   E  +  + I +    D G YT +A    
Sbjct: 3168 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3224

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
                            +R S  L   AP  P     LQ L  + V  G        +SG 
Sbjct: 3225 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3265

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P P++ W      +       F   G +++L + E FPED   YTCEA N  G   T A 
Sbjct: 3266 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3325

Query: 710  LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            L+V+ P     D   P +    I+  +    S GQ     C ++G       + +D K  
Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3383

Query: 762  CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             K +  F + Q ED + L + +  P   G Y  +  N VG+ S   +L L+
Sbjct: 3384 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3434



 Score =  102 bits (253), Expect = 5e-21
 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             +++ E  K RAG SV+L   ++G    T  W K  K++Q +  + VEN+ + + + I  A
Sbjct: 26876 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 26935

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              + + GCY L + N +GS  A + + ++DKP PP G      + +  +TL W   + DGG
Sbjct: 26936 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 26995

Query: 1361  SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             + +  Y +E  +++   W    + L  C  T+  +   +  +EY FRVRA+N YG  EP 
Sbjct: 26996 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 27052

Query: 1417  QESEL 1421
             +   +
Sbjct: 27053 ESDSV 27057



 Score =  101 bits (252), Expect = 6e-21
 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)

Query: 1236  MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
             +PP +   ++  E   V+AG +V     + G    T  W     +I+  EH  VE     
Sbjct: 17506 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 17565

Query: 1293  SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
             S LTI    +   G Y + V N  GS+   V+LTV+D P PP G     D+    +T+SW
Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 17625

Query: 1353  YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
                  DGGS V +Y +E  D+   TW  +++  S T   +  L    EY FRVRA N  G
Sbjct: 17626 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 17685

Query: 1412  TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
                P  +S  T    K  P  P  +  V+D  E    V +     +    ++ +Y +E R
Sbjct: 17686 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 17743

Query: 1470  LGSGKFGQV 1478
               +GK+ +V
Sbjct: 17744 EVTGKWVRV 17752



 Score =  101 bits (252), Expect = 6e-21
 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+ +M P+   + +   V AGES ++   + G    T  W+K  +++  +  +++++++
Sbjct: 22540 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 22596

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L++  A +   G Y L  +N  G R   VN+ V+D+P PP G    S + +   TL
Sbjct: 22597 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 22656

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGGS + +Y +E  +++   W  + A  ++ S  V  LL  +EY FR+ A+N 
Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 22716

Query: 1410  YGTSEPSQESELTTVGE--KPEEPK 1432
             YG  EP +   +        P+ PK
Sbjct: 22717 YGVGEPLESEPVVAKNPFVVPDAPK 22741



 Score =  101 bits (251), Expect = 8e-21
 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)

Query: 1243  FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
             F +   VRAG S+ LF    G    T  W K    +  S    +  +++ S LT+    +
Sbjct: 28363 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 28420

Query: 1303  EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
                G YTL VEN  GS+     + V+D P PP G     D+   S TL W     DGG+ 
Sbjct: 28421 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 28479

Query: 1363  VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             +  Y +E  +++ ++W+ ++  C    F V DL     Y FRV A+N YG  EP +  E 
Sbjct: 28480 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 28539

Query: 1422  TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
                 E+P  P+  D V+ S         +P+ D         +   QK SDF+ +E    
Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 28598

Query: 1472  SGKFGQVFRLVEK 1484
                   V RLVEK
Sbjct: 28599 KQLTFTVERLVEK 28611



 Score =  100 bits (250), Expect = 1e-20
 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             ++F +   ++AGE+  L   V+G  P T  W K  K+++ +  ++++ ++  + L    +
Sbjct: 21465 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 21524

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              +   G YTL   N  G  +   N+ V+D+P PP G    +++ S    LSW+    DGG
Sbjct: 21525 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 21584

Query: 1361  SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             + +  Y ++  +++   W  +A+  + T   V  LL  +EY FRV A+N YG  EP +  
Sbjct: 21585 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 21644

Query: 1420  ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
              +  V     P+ PK+ EV     D        P+ D  +  IN        Y +E R  
Sbjct: 21645 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 21694

Query: 1472  SGKFGQVFRLVEKKT 1486
               K GQ +    KKT
Sbjct: 21695 -DKAGQRWIKCNKKT 21708



 Score =  100 bits (249), Expect = 1e-20
 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V AGE +++     G      TW K    ++++  +  E++EN S LTI  A +E  G Y
Sbjct: 22159 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 22218

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + + N  G     +N+ V+DKP PP G     ++ + S+TLSW    YDGGS++ +Y +
Sbjct: 22219 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 22278

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             E  D++  TW+ + AT   T+     L    EY+FR+ A N YG S
Sbjct: 22279 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 22324



 Score =  100 bits (248), Expect = 2e-20
 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)

Query: 512  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
            V   F S +K+  ++EG      C + G P+P+I W  +G+ I    +Y     + G A 
Sbjct: 1289 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1348

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
            L I   LPED G YT  A N  G   CS  + V          Y   L PV+  +  +P 
Sbjct: 1349 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1408

Query: 624  -------------------------------------------------IFLQGLSDLKV 634
                                                             +F+      K 
Sbjct: 1409 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1468

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            ++G      ++V G P PE  W H+G +I    +     ++ GTQ SL I    P D+G 
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1527

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            +T  A N AG      +LTV+      +P F+ K ++V    G  + +     G+P P +
Sbjct: 1528 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1587

Query: 753  HWLRD 757
             WL++
Sbjct: 1588 VWLKN 1592



 Score =  100 bits (248), Expect = 2e-20
 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)

Query: 2     GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
             G+V   A++  S  +L     +V  +PL     FI P  ++ + E   AKFE  V   P+
Sbjct: 11818 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 11868

Query: 62    PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
                 W +  Q IT   RF L+  G + +  +   A  +E +  +  E  + SG       
Sbjct: 11869 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 11927

Query: 115   --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
                     + VT +      F  +L    +                       KT    F
Sbjct: 11928 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 11987

Query: 145   SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
                +++    I  E                P F  KL      E       C+I+    P
Sbjct: 11988 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 12047

Query: 191   QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
              V W K    ++PS    +      ++L +    + D+G YTC    G+ K S   ++  
Sbjct: 12048 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 12104

Query: 249   ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
                       S++ +++    F  ET+ +  D+            +     I +E K+ S
Sbjct: 12105 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 12162

Query: 288   LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
             L       NC   Q GG    AAN +       K      L   KD   TA +T      
Sbjct: 12163 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 12218

Query: 342   SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
              S         L+  +++P  +      + P  E +      R      +    G   + 
Sbjct: 12219 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 12268

Query: 396   SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
             +K       +  +      +F    + Q V+E  T    CEVS     +V WF  GT + 
Sbjct: 12269 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 12325

Query: 456   RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
             + +   E+  D     L +      D  TY+C A + +   SC+       L V+     
Sbjct: 12326 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 12375

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
             F   L D  V E +    +C +      ++ W  +G  I+  +      +  V  L I  
Sbjct: 12376 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 12434

Query: 573   ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
              L +D   Y+C    A      S  +TV E+++                  +F + L+++
Sbjct: 12435 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 12472

Query: 633   KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
             +V +   + +  +VS  P  EVIW     EI E+  +     G +  L IQ    ED G 
Sbjct: 12473 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 12531

Query: 693   YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
             Y C   +S    RT   + V E        FISKP+++    G+     C+I+ + FP V
Sbjct: 12532 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 12582

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
              W RD K L +    ++V+ +     LV+K       G Y +++
Sbjct: 12583 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 12625



 Score =  100 bits (248), Expect = 2e-20
 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
             MPP I    E  +V  G +V +  K+ G    T TW K        ++ +    H+    
Sbjct: 16116 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 16174

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
              ++   L I  +R+   G YT+   N LG+   ++ L V+ +P PP G      + +  +
Sbjct: 16175 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 16234

Query: 1349  TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
             TLSW+    DGGS + +Y IE  ++  KTW  +++  +  ++ +  LL  HEY FR+ A 
Sbjct: 16235 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 16294

Query: 1408  NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             N YG  EP        +  +PE  ++   V  + D      V   ++T+N E+   D
Sbjct: 16295 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 16343



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)

Query: 289  EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
            E  + +K    PQR  S P       +P     P E+ +++             ++KT+ 
Sbjct: 739  ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 796

Query: 344  SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
              T +   V   PR       SP     K   P             G +  ++ +A   +
Sbjct: 797  LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 842

Query: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
              E    S+  K     ++  VK ++T   R      P P+   F +     + E  +EV
Sbjct: 843  QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 898

Query: 464  YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
             ++ G   + +     R+          A+   +      VE   +    P+  S LK+ 
Sbjct: 899  KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 952

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
             VIEG+   L+C + G P P +TW      I+ +   + T ++G+A L I++A  ED G 
Sbjct: 953  TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 1012

Query: 581  YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
            +TC A N  G VS S ++ V      EK+++  +E                         
Sbjct: 1013 FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1072

Query: 615  -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
               P +P AP F+      K+++G  V    QV GNP P V W  +G  +     +   +
Sbjct: 1073 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1132

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             ++  +  L I   F +D G YT    N  GE    A L  +  ++
Sbjct: 1133 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1178



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P+ +M P+   F +   V AGE+  L   V G    T  W++  K+I+ES   +++N++ 
Sbjct: 23623 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 23679

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
              + L +  A +   G Y L   N  GS+   VN+ V+D+P PP G    + + S   +L+
Sbjct: 23680 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 23739

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
             W     DGGS +  Y +E  +++   W  +A+   + S  V  LL  +EY FR+ A+N Y
Sbjct: 23740 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 23799

Query: 1411  GTSEPSQES 1419
             G  EP + +
Sbjct: 23800 GVGEPLESA 23808



 Score = 97.8 bits (242), Expect = 9e-20
 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)

Query: 426   KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +E   VK+ C++    +  +V W+     +   E     YED G   L +      D GT
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 31638

Query: 485   YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
             Y C   N  G+ S                 C  T++      + + ++E  P F+  L +
Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 31698

Query: 523   CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
                  G++     ++   P P +TW  +GQ I+   +        + G+ +L I     +
Sbjct: 31699 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 31758

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
             D   YT +A N  G+ SC A +TV           L P        P+F + L++ +  +
Sbjct: 31759 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 31808

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
             G  V   ++VSG PPP + W  +G  +    +      G   ++L I++  PEDTG Y  
Sbjct: 31809 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 31868

Query: 696   EAWNSAGEVRTQAVLTVQ 713
              A N+AG    QA L V+
Sbjct: 31869 TATNTAGSTSCQAHLQVE 31886



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 69/251 (27%), Positives = 116/251 (46%), Gaps = 39/251 (15%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G     AS+ +   S S   +R+ +    ++P F + P ++ +  G +A FE  V G   
Sbjct: 6243 GQYSCSASNPLGTASSS---ARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQP 6299

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
             ++TW ++ + I  GG + + C +  T  L I  V + D G+YTC+ATN  G    + +L
Sbjct: 6300 MRITWSKDNKEIRPGGNYTITC-VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMGRF 180
            +V+                                   PPKF  KL    V K+G+  + 
Sbjct: 6359 SVKE----------------------------------PPKFVKKLEASKVAKQGESIQL 6384

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             CKI+G P+ +V+W + +  L  S + ++S  N + +L I+  + +D G Y C   NG G
Sbjct: 6385 ECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG 6444

Query: 241  KASMSAELSIQ 251
             AS S  L+++
Sbjct: 6445 DASCSTALTVK 6455



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G +V L     G    + +W+K    ++ESE ++   +EN   L+I  A++EH G Y
Sbjct: 27575 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 27634

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T++++N +      + +  +  P  P G     +I++ S+ LSW     +GG  +  YSI
Sbjct: 27635 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 27694

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  +++   WK + ++   T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 27695 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 27742



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)

Query: 161   PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
             P+   ++    V  GQ  RF   +  +P  +V W    V LQ S+++  +  +G+  LEI
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 32433

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
                + DD G Y  +  N  G+AS  A L + G D    +  R  +     V  E+T    
Sbjct: 32434 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 32493

Query: 279   --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
               +S   K   +EA++  +   S     +    + S  +    ++++S     ++  +  
Sbjct: 32494 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 32550

Query: 337   VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
               +K  +++   AAR+  +PR+    +    GE  +          PT    L    V+S
Sbjct: 32551 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 32602

Query: 397   KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
              +A  ++     + +   +  S   S E     V EN   K   E +  I K  V     
Sbjct: 32603 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 32660

Query: 451   GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
              +P R +     V           +K+  R  S   S   + +  +   + T +V+ L V
Sbjct: 32661 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
                 P  +  LK  A    +   L C V  + +    +TW  +G+ ++    +       
Sbjct: 32715 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771

Query: 564   GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
             G  EL I +    D G Y C      G      Q    A+ ++HEK        KS +K+
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831

Query: 610   EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
                     ++P AP       + + GL D  V   S     V+ +G P P  IW  +G  
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891

Query: 663   IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             I +   +   +      L I +    D+G YTC   NSAG V +   LT++   D
Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 32946



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG +V L   V G    T +W K    ++ +E +K+    N   L + +  ++  G Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN  GS+ A + L V+DKP PPA     + + S    LSW     DGGS + +Y +
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 19425

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             +  +++   W ++ AT   TS +V+ L+  HEY+FR+ A N YG  +P
Sbjct: 19426 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 19473



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)

Query: 5     KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
             K +    I+KTS + +  R  +    E  AF      + I EG     +  + G  +  V
Sbjct: 33018 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 33068

Query: 65    TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              W  NG  +T+   +    G+ G+  +L I      D G  TC +    G  +   +LT+
Sbjct: 33069 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126

Query: 124   EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
                          SK L D   APA  ++P                  + EGQ   F+C+
Sbjct: 33127 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 33156

Query: 184   ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
             I+G P P++ W K N+P+  S+ VS+S    +  LEI   +  D G YT    N  G+ S
Sbjct: 33157 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 33216

Query: 244   MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
              +A L +  L                 V +    V+ + S   SL+   +++S   S+ +
Sbjct: 33217 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 33259

Query: 302   RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
             +  S    ++S      E K  S      ++ Q   ++ +SSS                +
Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 33304

Query: 362   GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
             G+ + +  E                    S   + KA  R IP         PK E+ P 
Sbjct: 33305 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 33336

Query: 422   SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
                + E + +   C  +G P PEV W   G  +  QE G   +        L ++  + +
Sbjct: 33337 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 33396

Query: 481   DSGTYSCTASNAQGQLSCSWTLQVERL 507
             D G Y+ +  N  G  S +  + +  +
Sbjct: 33397 DGGLYTLSLGNEFGSDSATVNIHIRSI 33423



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)

Query: 1228  PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P T      PP + + F +   +R GE+  L G+ +G      +W K    + E +   +
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
             + +     L  + A++   G Y ++VEN  GSR+    + VVD+P PP G     ++   
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
              + +SW     DGGS + +Y IE  +     W  + +  + T+  V  LL   +Y FR+ 
Sbjct: 16928 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987

Query: 1406  AINVYGTSEPSQESELTT-----VGEKPEEP 1431
             A N+YG S+P     +       V + P++P
Sbjct: 16988 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 17018



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)

Query: 1214  LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
             +G    + + +    K P      P I     D  V  GE + +          T +W K
Sbjct: 14366 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422

Query: 1274  FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
               K+++ S+ + ++N    + L +  + +   G YT+ +ENKLGS  A +N+ V+  P P
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 14482

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
                   ASDI  SS  L+W    +DGG+ +  Y +E  ++  +T+  + +  +  S+ V+
Sbjct: 14483 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 14541

Query: 1393  DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
             DL+P+ EY FRV+A+N  G  E   E +   + + P++P D   +VEV +   +   + +
Sbjct: 14542 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 14600

Query: 1450  RTVTINTEQKVSDFYDIEERLGSGK 1474
             +    +   K+  +  I E++  G+
Sbjct: 14601 KPPLYDGGSKIMGY--IIEKIAKGE 14623



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)

Query: 506   RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
             ++A +E+ P    ++      EG      C +       ++TW    + ++ +     T 
Sbjct: 31561 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 31619

Query: 562   EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
             E GVA L+++D    D GTY C   N  G+ S  A + V               KK  R+
Sbjct: 31620 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 31679

Query: 609   SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
             ++ + L   P + T P++     +     G  V   V ++ +P P V W  +G +I+  +
Sbjct: 31680 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 31734

Query: 668   D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
             +   + FE     + L I  V  +D   YT  A N  GE   +A LTV     P D T +
Sbjct: 31735 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 31794

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
             P F     +     GQSV     ++G P PT+ W +DG+ L        + +  D + L 
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854

Query: 781   LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             ++   P   G Y +   N  G  SCQ  L ++
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886



 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)

Query: 1249  VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             ++AG+++ L    + G      +W K  K I+ S+  ++ ++   S LTI  A ++  G 
Sbjct: 20390 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+   N  G++   V +TV+D P PP G    S++ +   TL+W     DGGS ++SY 
Sbjct: 20450 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 20508

Query: 1368  IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E  +++   W    +++ +CR  +     L+  +EY FRV A+N YG  EP Q   +  
Sbjct: 20509 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 20565

Query: 1424  VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             V    P  P ++ EVS+       V   T T++ ++ V D
Sbjct: 20566 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 20598



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S+ +F  + G      TW K    I       +EN+E+ + L I    +   G +
Sbjct: 20788 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 20845

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + +EN  G +   VN+ V+D P P       +DI   S+TL W     DGGS + +Y +
Sbjct: 20846 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 20904

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++    T C   ++ V  L    EY FRV A N YG  EP++ +E     E 
Sbjct: 20905 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 20964

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
             P  P D + + D  +    + +     +   K++ +    +R GS ++  +
Sbjct: 20965 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 21014



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+  M    ++F +   V+AGE +++   + G      +W K   +I+E    ++ +++
Sbjct: 25786 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 25842

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
             N + LT+    +   G Y L ++N  G+R   VN  V+DKP PPAG    + + +   +L
Sbjct: 25843 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 25902

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             SW     DGG+ +  Y +E  ++++  W       + TS  V  LL  +EY FRV  +N 
Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 25962

Query: 1410  YGTSEP 1415
             YG  EP
Sbjct: 25963 YGVGEP 25968



 Score = 94.4 bits (233), Expect = 9e-19
 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ L   V+G  P   TW K  + I  +    ++ +E+ S L +    +   G Y
Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 29515

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN+ G + A V + V D P P        ++   S+T++W   + DGG+ V +Y +
Sbjct: 29516 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 29574

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++A + +K + T C  T + +  L+    Y FRV   N+YG  EP + S+   V E 
Sbjct: 29575 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 29634

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             P  P  ++EV D       V   TVT+  E+ + D
Sbjct: 29635 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 29661



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+A E +++     G    T  W K  + ++E+  + V +S+  + L+I  A +E  G Y
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 25465

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L V N  GS    + + V+D+P PP G     ++   S+T+SW    YDGG  + +Y +
Sbjct: 25466 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 25524

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++ + TW  ++     TS  +  L    EY+FRV A N YG S  S+ S    V E 
Sbjct: 25525 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 25582

Query: 1428  PEEP 1431
             P  P
Sbjct: 25583 PFSP 25586



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 1250  RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
             +AG  + +   + G      +W    K +K +++  H      ++E +EN S + I   +
Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882

Query: 1302  QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
             + H G Y++  +NK G + A   + V+D P PP      SDI   S  LSW     DGG 
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 15941

Query: 1362  AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
              ++ Y IE      K W ++   C ST+F V DLL + +Y FRVRA N +G   P +  +
Sbjct: 15942 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 16001

Query: 1421  LTTVGEK--PEEPKDEVEV 1437
              TT  +   P +P  ++++
Sbjct: 16002 RTTARDPIYPPDPPIKLKI 16020



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 60/220 (27%), Positives = 102/220 (46%), Gaps = 36/220 (16%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F L P ++ +  G +  F+  V G    ++TW ++ + I  GG + +   +  T +L 
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLT 7270

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            +  V + D G+YTC A+N +G    + +L V+                            
Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE--------------------------- 7303

Query: 153  PSIWGECPPKFATKLGRV-VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
                   PP+F  KL    +VK+ +  R+ CKI G P+ +V W K    +Q S++  +S 
Sbjct: 7304 -------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 7356

Query: 212  KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
             + + VLE+H ++ +D G YTC   N +G AS S  L ++
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            + P F     +L +K    A FE R+   G P   V W  +G+P+ +  R  +     G 
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1759

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
             SL     +  D G  TC ATN  G    +  L V  E S  ++   P   K L      
Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1819

Query: 147  PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
              +    ++ G       +  P        V V EG+  RF C++TG PQP+V W     
Sbjct: 1820 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1879

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             ++ S R  V   +G+  L+I      D G       N  G      +L IQ  +   RS
Sbjct: 1880 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1937

Query: 260  FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
             +R       +        +  E  K+D      ++K     +R          +     
Sbjct: 1938 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1997

Query: 319  ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
             SK +   +       T V  K+          ++             + EE+K  A   
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2057

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              T PT +P              +I +    ++  PK   + QSQ V +     FR  V 
Sbjct: 2058 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2102

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
            G P PE  W+  G  + R +     + +     L +      DS +    A N  G+ S 
Sbjct: 2103 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2162

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
               L V+   ++    +F+  L+D    E             P  ++ W  +G  +    
Sbjct: 2163 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2218

Query: 558  --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
              R   +  V  L I      D   Y+C              V V ++     ++ ++  
Sbjct: 2219 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2264

Query: 616  APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
            A  +     F++ L D++V +     +   VS    PE I   W HN  E++ +  +   
Sbjct: 2265 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2315

Query: 673  QRGTQHSLCIQEVFPEDTGTYT 694
             R  + +L +++V  ED G Y+
Sbjct: 2316 SRRGRQNLTVKDVTKEDQGEYS 2337



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
             P A++ P+   + +   V AGE+  L   + G       W K  K+++E+   M+++++ 
Sbjct: 24705 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 24761

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L +    +   G Y L + N  G++   + + V+D+P PP G    + + +    L
Sbjct: 24762 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 24821

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y IE  +++  +W +++T  ++ ++ V  LLP +EY FRV A+N 
Sbjct: 24822 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 24881

Query: 1410  YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
             YG  EP +   +T     KP  P    EVS
Sbjct: 24882 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 24911



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
             T +  TV+      T   + MP + I  P      AG  VEL   + G  P   +W    
Sbjct: 29723 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 29776

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
              +++ESE + VE     +KLTI        G YTL ++N  G+    + + ++DKP PP 
Sbjct: 29777 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 29836

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
             G     +I ++S+T+SW     DGG+ +  Y +E  D+    W  ++ +   ++F    L
Sbjct: 29837 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 29896

Query: 1395  LPDHEYKFRVRAINVYG 1411
                +EY FRV A N +G
Sbjct: 29897 TEGNEYVFRVAATNRFG 29913



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            +P+T  P  +   +N+ + EG +   E  + GYP P VTW+R    I S   F +     
Sbjct: 938  IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 995

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
            G   L+I     ED G++TC A N +G    +  L V+ S   +     V++   T   R
Sbjct: 996  GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1055

Query: 144  F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
            F  S   V T  S+  E         P F TK     + EG    F C++ G P+P V W
Sbjct: 1056 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115

Query: 195  LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             K  VPL    R  VS +++ G   L I     DD G YT +V N  G+ S SA L
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AGE V++     G  P T TW K  K +       +EN+++ S LTI    +   G Y 
Sbjct: 27284 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 27343

Query: 1310  LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             L +EN +G  + + V++ V+D P           +   ++TL W     DGGS + +Y I
Sbjct: 27344 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  D+  +TW  ++  C STSF + DL     + FRV A N  G  EP + +E     E 
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 27462

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
             P  P  ++ + D  +    + +     +    ++++  + ER G G+
Sbjct: 27463 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 27506



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+ G+ +++   ++G    T TW K    ++++  + V +S + + L+I    ++  G Y
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + V N +G + A + +  +DKPDPP G     D+ + S+TLSW    Y GG  + +Y +
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 23360

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             +  D+    W  + AT   T+  V  L    EY+FR+ A N YG S
Sbjct: 23361 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)

Query: 1248  KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
             KV+AGE V +   VTG       W K    I++          +V  SE  ++L+I  A 
Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468

Query: 1302  QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
             +E  G YT+   N+LGS    V++ V D+P PP      +DI++ S  L+W     +GGS
Sbjct: 15469 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 15527

Query: 1362  AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
              +  Y I+  D++ K   W+E+  T     + +  L+P+ +Y+FRVRA+N YG S+  + 
Sbjct: 15528 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 15587

Query: 1419  SEL 1421
              ++
Sbjct: 15588 DKV 15590



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)

Query: 1226  PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
             P P        PP++I       +Q ++ G+++ L   + G      TW K  +      
Sbjct: 17204 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 17263

Query: 1283  HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
              + V  +  GSKL I  A  E  G Y+L VEN  GS+   V + V+DKP PP      S+
Sbjct: 17264 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 17320

Query: 1343  IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
             IR  S  L+W     DGGS + +Y +E  D A+  W  L AT +  S   + L   ++Y 
Sbjct: 17321 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 17380

Query: 1402  FRVRAINVYG 1411
             FRV A N YG
Sbjct: 17381 FRVAAENQYG 17390



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)

Query: 1232  PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
             PKA    +PP+I    + +KV   RA  ++ LF  + G       W   R   +  +   
Sbjct: 21849 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 21906

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             +E++ + + L +    +   G Y L VEN  GS+ A VN+ V+D P PP       ++  
Sbjct: 21907 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 21965

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S+TL+W     DGGS +++Y +E  +S  K +  +AT C  TS+ V  L     Y FRV
Sbjct: 21966 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 22025

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A N YG   P++ +E     E+P  P
Sbjct: 22026 LAENEYGIGLPAETAESVKASERPLPP 22052



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)

Query: 1249  VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             V AG  + +   V+G  P T TW M  R   QE+    +E +   S + I   ++ H G 
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 16592

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
             Y+LL +N+ G R+  + + V+D P  P GTP  A ++ + S  L+W+    DGGS + +Y
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 16651

Query: 1367  SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
              IE  +S  + W  +  T    +  VQ L+    Y FR+ A N  G     + SE   + 
Sbjct: 16652 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 16711

Query: 1426  EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
             E    PE P+D +EV        EV   TVT+       D       Y +E RL G+ KF
Sbjct: 16712 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 16763

Query: 1476  GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
                     K T      + +     KE +     +S +N +   K   C
Sbjct: 16764 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 16805



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ LF  + G       W K   +I+++  + V +S   + L +    +   G Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 23011

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL +EN  G++ A V + V+D P PP      ++I   S++++W     DGGS +++Y +
Sbjct: 23012 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 23070

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++  + T C   S+ +  L     Y FRV A N YG   P+Q ++   V E 
Sbjct: 23071 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 23130

Query: 1428  PEEP 1431
             P+ P
Sbjct: 23131 PQPP 23134



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)

Query: 1228  PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
             P   P      +++++P+   D++ + G  V   G +  T PI       C W K  + I
Sbjct: 30118 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 30177

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
               S+   +  SE  ++L I  A +   G Y L++ENK G +   + + V+  P+ P G  
Sbjct: 30178 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 30235

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
                DI+  S+ +SW   + DGG+ +  Y +E  +     W  + +  R TS  V+ L  +
Sbjct: 30236 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 30295

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
              EY FRV A N +G S+P +  E  T       PE P +  EV D  +    + +     
Sbjct: 30296 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 30355

Query: 1455  NTEQKVSDFY 1464
             +   +V+ +Y
Sbjct: 30356 DGGSRVTGYY 30365



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)

Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
           AP F Q L  + V++GS  T    +SG P PEV W  +G  I  S            +  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
           L I  V   ++G Y+ +A N +G+  + A L V+   +   P F+ + +S+T   G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122

Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
           +   + G P P V + RDG  + + +  F++ Q  D+++L++ +  P  +G Y +   N 
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 800 VGECSCQVSLMLQ 812
           VG  +    L++Q
Sbjct: 182 VGRATSTAELLVQ 194



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)

Query: 408  QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
            Q++   P     P+   V E +T +FRC V+G P+P+V W+L G  +R+ +     Y+  
Sbjct: 1835 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1892

Query: 468  GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
            G HYL ++  ++ D+G    TA N +G +     L++++         F SVL+      
Sbjct: 1893 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1946

Query: 528  GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
             +  V     LQ  V+    P        +  L   + I + +   E+   EL  +    
Sbjct: 1947 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 2004

Query: 576  EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
             + G Y  +              E  L +       W      E+K +   E  + +   
Sbjct: 2005 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2064

Query: 619  KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            KP          AP   + +    V  GS     V+V G P PE  W  NG +I+ S+  
Sbjct: 2065 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2124

Query: 670  H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
            + +        L I++V  ED+ +   +A N AGE  + A L VQ     T   F  + +
Sbjct: 2125 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2181

Query: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
             V A    ++        +PF  V W +DG
Sbjct: 2182 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2211



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 69/286 (24%), Positives = 118/286 (41%), Gaps = 46/286 (16%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F ++L+ V V +   + L+C+V+  PP  + W  N + ++++K   L+   S+ ++ I
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 5014

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA----SENTKAPEMKSRRPKSSL--- 1210
             K  P D G Y+C+  N+ G   CS +V + + P+     ENT      S   +S++   
Sbjct: 5015 TKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGS 5074

Query: 1211 PPVLGT-------------------ESDATVKKKPAPKTPP------------------- 1232
            PP+  T                   +S AT++ +                          
Sbjct: 5075 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF 5134

Query: 1233 -KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                 P QI++  +   V   + + L   V GT  +   W+K  KQI  S +  +    N
Sbjct: 5135 LLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194

Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
             +   I +  ++  G YT  VEN  GS      L V+D+  PP+ T
Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 5240



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)

Query: 1232  PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
             PK  + P  I      +    VRAG  + LF  V G      TW K      +++ +   
Sbjct: 18597 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 18653

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             V+  +  + L I  + ++  G Y+L + N  G +   VN+ V+D P P +     SD+  
Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 18712

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S  +SW     DGGS V  Y +E  ++  KTW  +    + TSF+V +L+P +EY FRV
Sbjct: 18713 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 18772

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A+N YG   P+   +     +   EP
Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEP 18799



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)

Query: 1228  PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             P   P    P  I+  PE +          +RAG ++ L+  V G  P   TW K    +
Sbjct: 19675 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 19734

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             ++   + +++++  + L      +   G Y L +EN  G ++  + + V+D P PP    
Sbjct: 19735 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 19793

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
                +I   S  ++W     DGGS + +Y ++  D+  K+W  + T C  TSF V +L   
Sbjct: 19794 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 19853

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
               Y FRV A N YG  +P +  +     + P
Sbjct: 19854 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 19884



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)

Query: 1237  PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    + +KV   RA  ++ LF  + G       W K    +  ++  ++E + + +
Sbjct: 25104 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 25161

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L I    +   G Y L +EN  GS+ A VN+ V+D P  P       +++  S+TLSW 
Sbjct: 25162 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 25220

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DGG+ + +Y +E  ++  K +  +   C  T+F +++L     Y FRV A N YG 
Sbjct: 25221 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280

Query: 1413  SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
               P++ +E   V E P  P     V        +V   T TI  E+  SD
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 25322



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S  +     G      TW   R++ + ++ +++E   N ++L+I    +   G Y
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 24093

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L +EN  GS+ A V + V+D P PP       ++R  S  L W     DGG+ V++Y I
Sbjct: 24094 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 24152

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             +  +S  K +  +++ C  TSF V++L     Y FRV A N +G   P +  +     E 
Sbjct: 24153 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 24212

Query: 1428  PEEP 1431
             P  P
Sbjct: 24213 PSPP 24216



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             ++AGE +++   V G      +W+K  + ++++  + VE +   + L I    ++  G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+   N  G+    +++ V++KP PP G     ++ +  + +SW   +Y GG  + +Y +
Sbjct: 24383 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 24442

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  D+   TW  + AT   T+  +  L    EY+FR+ A N YG S P
Sbjct: 24443 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 24490



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 60/269 (22%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F QK   V   +G  ++LQC++S  PP  ++W  + K ++ +K   ++ +    S+ I
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 6517

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                  D G Y C A N+ G   CSC V                                
Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSV-------------------------------- 6545

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                           K   PP+ ++   D     G++VEL   V G QPI+  W+K R +
Sbjct: 6546 ---------------KFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGE 6590

Query: 1278 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDK 1330
             I+ESE+ ++   +N + L + +    + G Y   ++N  G R+    LTV      ++K
Sbjct: 6591 VIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK 6650

Query: 1331 PDP---PAGTPCASD---IRSSSLTLSWY 1353
            P+P     G P A +     +  L+  W+
Sbjct: 6651 PEPMTVTTGNPFALECVVTGTPELSAKWF 6679



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 73/292 (25%), Positives = 125/292 (42%), Gaps = 41/292 (14%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+   VA  + S  +L V+          E P  +   + + ++ G  A+F   + G P+
Sbjct: 3216 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3267

Query: 62   PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P+++W++  Q +++G +  FL D      ++L++     ED   YTCEA N  G    + 
Sbjct: 3268 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3324

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             L+VE                      P V +        PP   T L   V  EGQ  R
Sbjct: 3325 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3363

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F C+++G    +V+W   +  ++PS    +++      LEI     +D G YT +  N  
Sbjct: 3364 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3422

Query: 240  GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
            G+ S +A LS++    A  S + E      ++  +   VI +  K++ LE A
Sbjct: 3423 GQVSSTANLSLE----APESILHERIEQEIEMEMKAAPVIKR--KIEPLEVA 3468



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
           P F    QS  V E  T  F   +SG P PEV+WF +G  +       +++    G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
            +      +SG YS  A+N  GQ     T   E L   E A P+F   L+   V +G   
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121

Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
            LQ  V G P P + +  +G  IQ +   + + E  +  L I +A PED GTY+  A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
           +G+ + +A + V   E+  ++K++ ++  A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+L P +    EG TA+F+ +V G P P+  W  +GQ I +     +     GT SL+
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            I      D G++T  A N +G   ++V LTVE                       AVE  
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1551

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
                 +  P F  KL  V +KEG       + TG P P + WLK +  + P    ++ + 
Sbjct: 1552 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1607

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               G   L+I      D   YT   +N +G+ +   +++++
Sbjct: 1608 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)

Query: 1261  VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
             + G    + +W K    +     + VE+S   + L +   ++   G YT+ ++N  G+++
Sbjct: 20006 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
               +++ VV KP  P G     ++ + ++TL W     DGGS + +Y +E  DS N  W  
Sbjct: 20066 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 20125

Query: 1381  LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
              A+  + T+F V  L    EY FRV A N YG  E
Sbjct: 20126 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 20160



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)

Query: 1237  PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    FP     VRAG ++++   ++G      T  +    ++ +     E +    
Sbjct: 26473 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 26532

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              + +  +     G Y +   N  G+ +A +N+ V+D+P PP G    SDI   S+TL W 
Sbjct: 26533 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 26592

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                YDGGS V +Y +   +++   W E+ AT   T   V  L    EY+FR++A N +G 
Sbjct: 26593 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 26652

Query: 1413  SE 1414
             S+
Sbjct: 26653 SD 26654



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)

Query: 1238  PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             P I++F  +      +++GES+ +   V G      TW K   +I++  +M++ +    +
Sbjct: 27955 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 28014

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L +  A ++H G YT+  +N  GS +A++ + V D P    G    ++I    +TL W 
Sbjct: 28015 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 28074

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DG + +  Y IE  +++   W  +   C + S+    L+  +EY+FRV A+N +G 
Sbjct: 28075 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 28134

Query: 1413  SEP 1415
               P
Sbjct: 28135 GRP 28137



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)

Query: 882  HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
            H EE+  QQ   +  +++    ++S   ++E   +  PA +      + + VKP+ +   
Sbjct: 722  HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 772

Query: 939  SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
            SE   K    + +   S + K     T     V   P+ A+P F      K  +P     
Sbjct: 773  SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 829

Query: 998  SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
              A    +      K LS    +   + +  +  A T+KP      AE   L     A  
Sbjct: 830  YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 886

Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
             +  KS +  E+KK+V   +       GTT  E+R E                       
Sbjct: 887  PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 940

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            T P     L++V V EG+ + L+C +S  P  T+ W      ++++    ++ +  +  +
Sbjct: 941  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
             I +A  ED G + C A N+AG    SC   V V +    E T   E  +   K  +   
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                +D ++ ++ A    P A   P  I  P  QK+  G SV    +V G       W K
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117

Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
                +      KV  N + G  KL I     +  G YT++V NK G   A  +L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)

Query: 405  MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
            ++G++ +   K + +P         Q+V E   V+   +VS +   E  W  +G  V+  
Sbjct: 2340 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2398

Query: 458  EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
            +  + +  D  SH L +      D+G YS T       L  S + +V   +V  + P   
Sbjct: 2399 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2450

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
              LKD  VIEG   VL+C V    V  + W LN + I+     ++  +     L I    
Sbjct: 2451 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2508

Query: 575  PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
              D G Y  +    +G+V  +  ++V + K                     ++GL DL  
Sbjct: 2509 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2544

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
             +   V   V++S +   +V+W     EI+ S  +  E  G  + L +  +  +D G YT
Sbjct: 2545 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2603

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
                  AGE  T   LTV           ISKP    T +  Q  +  C +A +P     
Sbjct: 2604 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2651

Query: 754  WLRDGKAL 761
            WLRDGK L
Sbjct: 2652 WLRDGKHL 2659



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 61/234 (26%), Positives = 96/234 (41%), Gaps = 46/234 (19%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F ++L+ V  A  KK+ L+CQV  D   T+ W+ +G+ L   K   +  E  + ++ I
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 3703

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
              A  +D G Y C A N+AG + CS  VTV + P                          
Sbjct: 3704 PLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP-------------------------- 3737

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              + VKK           + P  +  P       GES  L  K+ G+  I  TW K  K+
Sbjct: 3738 --SFVKK-----------VDPSYLMLP-------GESARLHCKLKGSPVIQVTWFKNNKE 3777

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            + ES  +++    + + L I   + E  G Y+    N +GS      + + + P
Sbjct: 3778 LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)

Query: 1086  DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
             D E R++ +   AP  K   QD+ V  GK L +     + P A   W    + L T    
Sbjct: 12987 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 13046

Query: 1145  ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
               +++ S   +  +K    D+G YK V +N  G+AE    + V D P             
Sbjct: 13047 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 13091

Query: 1205  RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
                    PV   E   T   +               +    ++ +  G S ++ G V   
Sbjct: 13092 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 13128

Query: 1265  QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
             + I   TW+    + +  E       + G +     + +   G    +  +N + +R   
Sbjct: 13129 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 13188

Query: 1323  VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
                   D P PP      +D+    ++L+W    YDGG+ + +Y IE+ D  +  W    
Sbjct: 13189 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 13241

Query: 1383  TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
             T R+   S  V D++   EY FRVRA N  G  +PS  +    V +  E P   V ++  
Sbjct: 13242 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 13301

Query: 1441  DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
             D+ +  V  +      +        I ER   GK   +    +LV + T KV       K
Sbjct: 13302 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 13361

Query: 1494  FFKAYSAKEKENIRQEISIMNCL 1516
             +    SA+ K  +     I+  L
Sbjct: 13362 YLYRVSAENKAGVSDPSEILGPL 13384



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG S  +     G       W K    ++   +  V+ +++ + LTI  A +   G Y
Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 26255

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL ++N L +    + + V+D P PP       D+   S  LSW     DGG+ V++Y I
Sbjct: 26256 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 26314

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  +++ K W  +   C   S+ V +L     Y FRV   N +G   P++  E   + EK
Sbjct: 26315 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 26374

Query: 1428  PEEPK 1432
             P  P+
Sbjct: 26375 PSPPE 26379



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             E + S  SE + P +     AP F + L +L V   S  T+  +V+G+P P V W   G 
Sbjct: 30907 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 30966

Query: 662   EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
             EI  +   +  ++ +G  H L I  V  +D   Y   A N  G V   A L V+ P    
Sbjct: 30967 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 31026

Query: 720   QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
              P  +    +V A  G+ V I    +G P P + W + G+ L  + GH++V+      +L
Sbjct: 31027 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 31085

Query: 780   VLKK-VQPWHAGQYEILLKNRVG 801
             V    V+   AG Y +  KNR G
Sbjct: 31086 VFPNGVERKDAGFYVVCAKNRFG 31108



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)

Query: 23    RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
             R D+M L E P  F LP  N     G   +F   +  +PEP VTW+++GQ I  G    +
Sbjct: 31679 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 31738

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
             +  +   +G + L I++V  +D  +YT  A N  G      +LTV       L  P    
Sbjct: 31739 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 31791

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             TL                    P F   L     +EGQ   F  +++G P P + W K  
Sbjct: 31792 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832

Query: 199   VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
              PL     +  + E      L I     +D G Y     N +G  S  A L ++ L    
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892

Query: 258   RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
             + F +  +     V+K++   +     L   E+
Sbjct: 31893 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 31924



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
             V+AG+++ L   V G       W K +    +  S  +K++   + SK ++  A++   G
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272

Query: 1307  CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
              Y +   N  GS  A   + V+DKP P        D+ S   T+ W     DGG  +Q+Y
Sbjct: 18273 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 18331

Query: 1367  SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
              +E  ++    W    AT  +    V  L+  +EY FRVRA N  GT  P++   +   T
Sbjct: 18332 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 18391

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
               +KP  P D  EV+   ++E  V +     +  + ++ ++
Sbjct: 18392 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 18431



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)

Query: 622   APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
             AP   + + D+    G    ++ Q+ G P P++ W   G E+ +S  +     G  H+L 
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591

Query: 682   IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
             +     ED G YTC A N  GEV T + L +Q       P +  K +   A +G ++ + 
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 30649

Query: 742   CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
                 G P P + W   G+ L +++ +  +   E    LV+K VQ   HAG+Y++ L N  
Sbjct: 30650 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708

Query: 801   GECSCQVSLMLQN 813
             G     + + +Q+
Sbjct: 30709 GTVDAILDVEIQD 30721



 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)

Query: 416  FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            F  + Q    KE  T+  F CE S  P  +V W+ +G  V   +    ++ D   H+L +
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2233

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
            L   T D+  YSC     +   + +      +L V      F   L+D  V E     L+
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2287

Query: 535  CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
            C V    +    W  N   ++       T   G   L ++D   ED G Y+ + +     
Sbjct: 2288 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2342

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                       KK++ K +        KP     LQGLSD KV +G  V + V+VS    
Sbjct: 2343 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2384

Query: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
             E +W+ +G E+Q S+  H       H L I+++  ED G Y+        +++G V   
Sbjct: 2385 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2443

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
            +V              I+  + V    G   ++ C ++     +V W  + + + K    
Sbjct: 2444 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2490

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
             + +       LV+ +      G Y++++  RV E +C +S+
Sbjct: 2491 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2530



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             + E ++  F  E+S    P   W L+G  + R   + E+  + G  +L L K +   +G 
Sbjct: 11408 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 11465

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
                 A NA         +    L V E+   F+  LKD  V E +    +C +  T    
Sbjct: 11466 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 11514

Query: 545   ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
             + W      I+ +         + HI    D+  +D G YT   E    + S   +VT  
Sbjct: 11515 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 11572

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
               K                    F+  L D  V +G   T   ++S +    V+W  N  
Sbjct: 11573 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 11611

Query: 662   EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
             ++  S        G  H L ++EV  +D      +      E+ + A L V E      P
Sbjct: 11612 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 11663

Query: 722   WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
             +F  K    TA     + + C ++ D    V W +DG+ +      + +  +     L +
Sbjct: 11664 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 11720

Query: 782   KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
             KK      G+Y          C C       N +  A L +  +P    ++  G      
Sbjct: 11721 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 11771

Query: 838   ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
              +    D +G     W  +GQ      D E +    K  +         T + + +A   
Sbjct: 11772 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 11827

Query: 890   QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
             +    L  ++L    +    LS  D+K    ++  F   + R+  PKT     R +   Q
Sbjct: 11828 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 11877

Query: 950   QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
             ++  D R  L K GT  + V +       A   F +      +    +G    E +  K 
Sbjct: 11878 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 11931

Query: 1008  VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
             +   K ++  +    +  V  +     +K   N +   T + + + + +    S + ++L
Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 11990

Query: 1068  KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
               D  + +  +    G +   K +  +G  P F  KLQD    E  +++LQC++S    A
Sbjct: 11991 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 12046

Query: 1128  TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
              + W  +GK +K +K  ++  +G    + ++KAL  D G Y C    D G  + S ++ +
Sbjct: 12047 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 12102

Query: 1188  DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
             +D          E+K  RP  S+  V+ TE+
Sbjct: 12103 EDR---------EIKLVRPLHSV-EVMETET 12123



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PPKA +  ++    +   +RAG  + L   V G       W K  K++   E + ++ + 
Sbjct: 29043 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               +   I    +   G YTL V+N  G++   V + V+D P  P G    S +     TL
Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 29159

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y +E  +++   W  +   C + S+ V  L+ ++EY FRVRA+N 
Sbjct: 29160 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 29219

Query: 1410  YG-----TSEPSQESELTTVGEKPEEPKD 1433
             YG      SEP       T+   P  P++
Sbjct: 29220 YGPGVPVESEPIVARNSFTIPSPPGIPEE 29248



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 47/230 (20%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+F +KL+DV+   G  ++L+C+VS   P ++ W  +G  + +      S   ++C++++
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                P D G+Y CVA N AG  ECS  +TV + P+ E T                     
Sbjct: 6801 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT--------------------- 6839

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                                      P+  +V  G S+     + GT P    W K  ++
Sbjct: 6840 --------------------------PDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE 6873

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            +   E   +   +  ++L +   +    G Y+ LV N  GS     +L V
Sbjct: 6874 LVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 6923



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AG+++++   V G    T TW K  + +++++ +  E +   + L I    +   G Y 
Sbjct: 21078 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 21137

Query: 1310  LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             L   N +G     + + V D P PP G     ++ S  +T SW     DGG  + +Y +E
Sbjct: 21138 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 21197

Query: 1370  IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
             +  + + TW ELA T   T++    L    EY+FRV+A N YG
Sbjct: 21198 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 21240



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)

Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
            EED  +     ++E +  V+  F   I++  ++EG    F CK+ GYP P++ W+KD + 
Sbjct: 1272 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1330

Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I+    +Q+D+ +DG  SL I  V  +D+  YT  A N  G A C+ +L VE
Sbjct: 1331 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)

Query: 21   PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
            P +++  P  EAP      ++  + +G+ A F  RV G P+P+  W++NG  I    R  
Sbjct: 2066 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125

Query: 81   LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
                      LVI  V  ED      +A N +G       L V+   AKQL         
Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2173

Query: 141  GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
                                  F  +L  VV KE   M  F C+ T  P  +V W K  +
Sbjct: 2174 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2212

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             +    +  +     +  L I  ++  D   Y+C++V        +A+L ++G   A   
Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2268

Query: 260  FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
            FV+E +          E+  ++S E+       + +E  +  K   + +RG       + 
Sbjct: 2269 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2328

Query: 313  QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
              +   E       K  +CK   +  P   +LQ  S     +   VQ E +       GV
Sbjct: 2329 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2387

Query: 364  LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
                G+E  +P+         +   L  +D+  + A      IP  G   S      S  
Sbjct: 2388 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2446

Query: 421  QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                +K+   ++       C+VS      V W+L    + + +  ++         L + 
Sbjct: 2447 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2505

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
            +    D G Y        G++  +  L VE++ ++         L+D    E Q+ V + 
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2554

Query: 536  SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
             +  + +  + W    + I+ +   +      + +L + + + +D G YT  A    G+ 
Sbjct: 2555 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2609

Query: 593  SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
              S  +TV               A SKP        L+D  V +  +     +V+ NP  
Sbjct: 2610 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2648

Query: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +  WL +G  +  + +   E  G +  L I     +D G YT +   S    +T A L V
Sbjct: 2649 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2704

Query: 713  QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            +          I K  +++T +  Q  + +  +       V W+++G  L
Sbjct: 2705 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2747



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 59/265 (22%), Positives = 102/265 (38%), Gaps = 48/265 (18%)

Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133
            +  CK  +   +D    S +    P F +KL D+    GK++ LQ  +    P +++W  
Sbjct: 7468 EYQCKATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFK 7527

Query: 1134 N-GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
            + G+ ++ +  I +S   ++ ++   +  P + G Y C  KNDAG  EC   ++V +   
Sbjct: 7528 DKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE--- 7584

Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
                                                        P  I++ PE  KV  G
Sbjct: 7585 --------------------------------------------PATIVEKPESIKVTTG 7600

Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
            ++  L   V GT  ++  W K  K++      K+      S L I+       G Y+  V
Sbjct: 7601 DTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEV 7660

Query: 1313 ENKLGSRQAQVNLTVVDKPDPPAGT 1337
            +N +G      +L V D+  PP+ T
Sbjct: 7661 QNPVGKDSCTASLQVSDRTVPPSFT 7685



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
             P+F     ++     + V+F   ++  P+P V W+  G  ++  +   +     D G + 
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
             L +    T D   Y+  A N  G+ SC   L V          + P F  +L +    EG
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 31809

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
             Q    +  V G P P + W  +GQP+    +      G+    LHI+D LPED G Y   
Sbjct: 31810 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 31869

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEY 611
             A N  G  SC A + V E+   +K E+
Sbjct: 31870 ATNTAGSTSCQAHLQV-ERLRYKKQEF 31895



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 67/283 (23%), Positives = 111/283 (39%), Gaps = 60/283 (21%)

Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1151
            + Q   P+F ++L+DV    G  ++  C +S   P ++ W  +GK LK +  +  S   +
Sbjct: 8051 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 8110

Query: 1152 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP 1211
              +++I K      G Y C A N  G A  S ++ +     +E    P    R     L 
Sbjct: 8111 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL-----TEGKNPPFFDIR-----LA 8160

Query: 1212 PVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
            PV     DA V                             GES +    VTGTQPI  +W
Sbjct: 8161 PV-----DAVV-----------------------------GESADFECHVTGTQPIKVSW 8186

Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             K  ++I+     ++   EN + LT+L   +   G YT    N++G       L + ++ 
Sbjct: 8187 AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERL 8246

Query: 1332 DPPAGTPCASD----------------IRSSSLTLSWYGSSYD 1358
             PP+ T   S+                  S  +T++WY ++ +
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 8289



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)

Query: 1225  KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
             +P+  TPP  A+ P  I  P+       +V+ G+ + L   ++G+   T TW+K      
Sbjct: 14664 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 14721

Query: 1277  -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
                              ++QE E         + ++NS+ G S+L +  + +   G Y +
Sbjct: 14722 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 14781

Query: 1311  LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
              VEN  G  +A   ++V+D P PP       DIR +S+   W     DGGS + +Y++E 
Sbjct: 14782 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 14840

Query: 1371  WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
              D    +  W  + +T R   ++V  L+   EY FRVRA N +G   P     L  V + 
Sbjct: 14841 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 14898

Query: 1428  PEEPKD 1433
             P  P D
Sbjct: 14899 PFGPPD 14904



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)

Query: 36   ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
            I P +++ + EG  A  E +V       V W+ N + I    R  +   ++GT   LVI+
Sbjct: 2448 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2505

Query: 95   AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
              H  D G Y        G  +    L+VE                              
Sbjct: 2506 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2533

Query: 155  IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
                   K    L  +   E Q   F  +++      V W   +  ++PS++  +     
Sbjct: 2534 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2585

Query: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
            +  L +  + +DD G YT      +G+   S +L++ G  + ++    +T A + +    
Sbjct: 2586 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2640

Query: 273  KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
             EV N  SK   L   +    + N  S   G        A           K+ + K S 
Sbjct: 2641 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2700

Query: 330  RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
            +   +   ++KT  ++T+   +          P   G+     GV+  S E+        
Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2760

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              +   +   +  + V      R +    +      K   KP+     EN TV F   VS
Sbjct: 2761 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2819

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
                P V WF +   ++  +    +  +   H L L      D+G Y+       GQL C
Sbjct: 2820 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2873

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
               L VE L +       +  +K+  V E +    +C V    VP + WL NG  I+ + 
Sbjct: 2874 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2925

Query: 559  S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
                  +  + +L I +   ED   YT +  N   QVS +  VT                
Sbjct: 2926 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2967

Query: 616  APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
                   PI +   L D+   +   +T  V V+        WL NG EI+ ++      +
Sbjct: 2968 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 3019

Query: 675  GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
               HSL I+ V   D   YT      AG+  + A L V+  H      F    + +    
Sbjct: 3020 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3071

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             +  +  C ++ +P  TV W++D + L + T   ++ + + V  L++   +   AG+Y +
Sbjct: 3072 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129

Query: 795  LLKNRV 800
            +    V
Sbjct: 3130 VAGGNV 3135



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)

Query: 1228  PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
             P T   A + P   +  F +  +V     + +    TG    T TW    K ++  + +K
Sbjct: 13383 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 13442

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             ++     ++L I  + +   G YTL +EN++ +   ++++ V+ +P  P       DI  
Sbjct: 13443 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 13501

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
              S+ L+W     DGGS +  Y +E  + + KTW K +       F V DL+   EY F+V
Sbjct: 13502 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 13561

Query: 1405  RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
              A N  G  EP+   E   ++T    P+ P++
Sbjct: 13562 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 13593



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PA  ++L  V  ++   +L   +   D  + I   L     K + F + +      + ++
Sbjct: 28546 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 28605

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             E+ + +    ++  AKNDAG +E                         P+ +   V+   
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 28637

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                 +K+     T     +  Q+I        +AG    +   ++G      TW     +
Sbjct: 28638 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 28687

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
             ++E++ + +  +++ + LT+  + +   G Y L +EN  G +   V + V+ +P P  G 
Sbjct: 28688 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 28747

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
                S + + S  LSW      GG+ + +Y +E  +S    W+ + ++ + T   V  L  
Sbjct: 28748 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
               EY FRV + N +G S+P + + +  + E P  P
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 28840



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)

Query: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
            S+DVV    +      G  + A P F +KP  Q++ E  +V F C+V G PKP V W   
Sbjct: 1059 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1118

Query: 451  GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
            G P+       +   +  G   L +      D+G Y+    N  G+ S S +L +E    
Sbjct: 1119 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177

Query: 510  MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
              +  S   +L    V     FV +  V G   P   +    +  +  ++     +A+  
Sbjct: 1178 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1233

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
            + ++  + +     +   E  + ++      T  E+  +   + +  + ++ S+     F
Sbjct: 1234 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1293

Query: 626  LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
               + + ++++G  VT   ++SG P P++ W  +G  I+  E +   F Q G + SL I 
Sbjct: 1294 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1352

Query: 684  EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
             V PED G YT  A N  G       L V+       P +I             PRSV+ 
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412

Query: 733  S 733
            S
Sbjct: 1413 S 1413



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 62/218 (28%), Positives = 93/218 (42%), Gaps = 32/218 (14%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            E P FI P  ++    G  A  + +V G PE +++W++    + S   + +        S
Sbjct: 7018 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFK-NNVAS 7076

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            LVI+ V   D G+Y+C+A N  GA   +  L ++   A++L                   
Sbjct: 7077 LVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK---ARKL------------------- 7114

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
                     PP FA KL  V    G    F C+I G    QV+W K  V L+  A +  S
Sbjct: 7115 ---------PPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTS 7165

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
              + +  L+I   +Q  +G Y C   N  G AS SA+L
Sbjct: 7166 FVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P  K       V  G+ L ++  +S  P  TI WT +G  LK T  I ++    L ++SI
Sbjct: 23230 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 23289

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y     N  GQ   S ++   D P  +  K P                  
Sbjct: 23290 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 23332

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              D + +       PP      QI  +   ++                   T  W      
Sbjct: 23333 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 23376

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
             +  +  +KV   + G++             + +  EN+ G   A  +  +V      +P 
Sbjct: 23377 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 23424

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
             PP GTP A+ I   S+ + W+    +GGS V  Y +E       +W   NKT        
Sbjct: 23425 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 23478

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              T F  Q+L    EY+FRV A N+ G  + S+ SE     +  + P
Sbjct: 23479 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 23524



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 66/242 (27%), Positives = 101/242 (41%), Gaps = 22/242 (9%)

Query: 13   SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
            +  SLSV+   V S    MP+   PA I P ++    EG  A+F+ RV G  + +V+W+ 
Sbjct: 3322 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3379

Query: 69   NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
              + I    RF        T+ L I   + ED G YT  A+N  G    T  L++E    
Sbjct: 3380 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP-- 3436

Query: 129  KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
                       L +R     +E    +  +  P    K+  + V  G + +F+C+I   P
Sbjct: 3437 --------ESILHER-----IEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 3483

Query: 189  QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
              +  W K    +  S + S+     +  LEI      D G YTC   N  G  S +A L
Sbjct: 3484 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543

Query: 249  SI 250
            ++
Sbjct: 3544 TV 3545



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
             F + L+D  V E    +  CQ+S +  A + W  NG+ +K  K     ++GS+  + I+ 
Sbjct: 12825 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 12883

Query: 1160  ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
                +D   Y C  ++   +A    + + V+         +AP ++     E+   +    
Sbjct: 12884 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 12943

Query: 1207  --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
               ++++  V G +                           + K    +   + A  P+I 
Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 13003

Query: 1242  QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
                +D  V  G+ + +             W K  + +       ++ +   +   IL A+
Sbjct: 13004 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 13060

Query: 1302  QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
             +   G Y ++++NK G  +  +NL V+D P P       ++     ++L+W     DGGS
Sbjct: 13061 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 13119

Query: 1362  AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
              +  Y +E  D   KTW  LAT R+ S  F V  L     EY FRV A N  GT EP + 
Sbjct: 13120 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 13178

Query: 1419  SELTTVGEKPEEPKDEVEVSDDD 1441
                     K + P   + V+  D
Sbjct: 13179 DNPVEARSKYDVPGPPLNVTITD 13201



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)

Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
            S TG+       E L   E  V++        E P   P     ++++ V+EG +   +C
Sbjct: 905  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             I GYP P V W+++D  I  S  FQI + + G   L+I +   +D  ++TC AVN  G 
Sbjct: 965  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023

Query: 1840 ATCTAELIVETMEEGEGE 1857
             + +  L V+  EE E E
Sbjct: 1024 VSTSCYLAVQVSEEFEKE 1041



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 48/234 (20%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+F + L+   +  G   LLQC+VS   P  I W  + K ++++K   L  + SL  + I
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 3890

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                  D G Y+CV  N+ G  +C C  T                               
Sbjct: 3891 FSFNSADVGEYECVVANEVG--KCGCMAT------------------------------- 3917

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                +K+            PP  ++  +D     G++V L   V G++PI+ TWMK ++ 
Sbjct: 3918 --HLLKE------------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 3963

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            I+E   +K+  S   + L I   +    G YT L EN+ GS Q  V   +V +P
Sbjct: 3964 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS-QTSVGELIVKEP 4016



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)

Query: 1052  NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
             N++P ++LK   +E +  D +  +  +  +A G ++  + SE+         P    +  
Sbjct: 14335 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 14394

Query: 1106  DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
             D+ V EG+KL +     + P  T+ W  +GK +K +  + +  +     + + K++  D 
Sbjct: 14395 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 14454

Query: 1166  GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
             G+Y    +N  G A  S  V V   P        ++K+              SD T    
Sbjct: 14455 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 14496

Query: 1226  PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                  PP+                             G  PI   ++  R++     ++ 
Sbjct: 14497 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 14528

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
             V + EN    T+          + +   NK+G  +     N  +   P  P   P   ++
Sbjct: 14529 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 14588

Query: 1344  RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
              +    ++T++W    YDGGS +  Y IE      + WK    C        ++  + L 
Sbjct: 14589 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 14645

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
                EY+FRVRA N  G SEPS+ +  T   +  + PK      +EV   DE
Sbjct: 14646 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 14696



 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 69/308 (22%), Positives = 120/308 (38%), Gaps = 73/308 (23%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F      V   +  ++ L+C++S  PP  ++W  + + L+++K   ++ +    S+ I
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 5576

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                  D G Y C A+N+ G   C C                                  
Sbjct: 5577 LNVDTSDIGEYHCKAQNEVGSDTCVC---------------------------------- 5602

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
               TVK K           PP+ +       V AGE  EL   + G QPI   W+K +++
Sbjct: 5603 ---TVKLKE----------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649

Query: 1278 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVDK 1330
             I+ESE++++   EN + L    A   + G Y   ++N  G R+    L       +V+K
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEK 5709

Query: 1331 PDP---PAGTPCASDIR---SSSLTLSWYG-------------SSYDGGSAVQSYSIEIW 1371
              P     G  C  + +   +  L++ WY              S Y+  S+++  S+E  
Sbjct: 5710 AGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQ 5769

Query: 1372 DSANKTWK 1379
            D+   T++
Sbjct: 5770 DAGTYTFQ 5777



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 59/236 (25%), Positives = 93/236 (39%), Gaps = 29/236 (12%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            PA    LQD   +EG+    QC+VS      + W    K +K ++F  ++Q      + I
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             +A PED G Y  VA N  GQ   +  ++++                 P+S L   +  E
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLE----------------APESILHERIEQE 3447

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
             +  +K  P  K               E  +V  G   +   ++     +   W K  ++
Sbjct: 3448 IEMEMKAAPVIKRKI------------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 3495

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
            I ES+   + +S+  S L IL  +   CG YT    N+ GS      LTV +   P
Sbjct: 3496 IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             VKE Q V F CEV+     +  WF     +      I + +D   + L +  A   D   
Sbjct: 12651 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 12708

Query: 485   YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
             Y+ + +N +G+ +  +  L VE   +  V P     LKD   +E +     C V    V 
Sbjct: 12709 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 12763

Query: 544   RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              + W  NG+ + +            H   I+D    D G Y                VT 
Sbjct: 12764 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 12807

Query: 601   HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
              + KS   +E L+  AP++     F++ L D  V +      + Q+S      V W  NG
Sbjct: 12808 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 12859

Query: 661   NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
              EI+E + + FE+ G+ H L I++   +D   Y C       + +++A L V+E P +  
Sbjct: 12860 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 12915

Query: 720   QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
             +P     P+ +  + G  V+    +  D    V WLR+   + +   H +++    +  L
Sbjct: 12916 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 12968

Query: 780   VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
              +  ++P   G+Y  + K++      +++
Sbjct: 12969 QICDIKPRDQGEYRFIAKDKEARAKLELA 12997



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V+V  G  L +   +S  P   +  + +G  LK T            ++++++++  D G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
              Y+  A N +G  +    + V D P                   P V+   TE   T+K 
Sbjct: 26546 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 26591

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P PK    + +   I+       ++   S  ++ +V+ T  +  T MK  K     E+ 
Sbjct: 26592 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 26641

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
                 +EN                    + + + S    V L     P PP+ TP  +++ 
Sbjct: 26642 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 26682

Query: 1345  SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
               S+T+ W+    +GGSAV  Y +E+ D  +  W++      R+T F V  +     Y+F
Sbjct: 26683 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 26742

Query: 1403  RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             RV A N  G  +PS  SE     +  E P++ V ++D  +    + ++    +   K++ 
Sbjct: 26743 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 26801

Query: 1463  FYDIEER 1469
              Y +E R
Sbjct: 26802 -YIVERR 26807



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 87/395 (22%), Positives = 147/395 (37%), Gaps = 84/395 (21%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+F +KL+ +   +G  + L+C V+   P +I W  + + +  ++    S   +   + I
Sbjct: 4675 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 4734

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             +    D G Y C A N AG  +CS  +TV +                            
Sbjct: 4735 SQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------------------- 4766

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                               PP  ++ P+ Q V     V+L   V GT P+T  W K  K+
Sbjct: 4767 -------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE 4807

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDKP 1331
            +       V   +  + L + AA+    G Y   + N +G+  ++  L V      + KP
Sbjct: 4808 LHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 4867

Query: 1332 DP------PAGTPCASDIRSS-SLTLSWYGSSYDGG--SAVQSYSIEIWDSANKTWKELA 1382
             P         T     I  +  + +SWY    DG   +A+Q + I   D        LA
Sbjct: 4868 SPVLVLRNGQSTTFECQITGTPKIRVSWY---LDGNEITAIQKHGISFIDG-------LA 4917

Query: 1383 TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL----TTVGE-KPEE--PKDEV 1435
            T     F +     ++   +   A N  GT+  S E ++    T + E KP E     +V
Sbjct: 4918 T-----FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDV 4972

Query: 1436 EVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL 1470
            E+  +    P  +   +  N E + S  Y + +R+
Sbjct: 4973 ELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV 5007



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
             R+++ ++    +++   G+ L +   ++     + +  EN+ G      S +     T +
Sbjct: 30267 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 30326

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
             + P+PP+  P   D+  SS++LSW     DGGS V  Y IE  +++   W         +
Sbjct: 30327 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 30386

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
             T + V  L+PD EY+FR+ A N  G SE S  SE        +KP +P  E+E+
Sbjct: 30387 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 30439



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)

Query: 1228  PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
             P+ PP   +    +      ++ AG+++ +   VTG    T  W K   ++ + + + ++
Sbjct: 15098 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 15153

Query: 1288  NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
             N    S+L I  A ++  G Y +   N  GS+ A   + V D P P          R   
Sbjct: 15154 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213

Query: 1348  LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
             L L+W     DGGS +  + IE  D+   TW++      +  ++  LL   EYKFRV A 
Sbjct: 15214 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 15272

Query: 1408  NVYGTSEPSQESELTTV 1424
             N +G   P +   +  V
Sbjct: 15273 NKFGCGPPVEIGPILAV 15289



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 59/235 (25%), Positives = 95/235 (40%), Gaps = 48/235 (20%)

Query: 1098 PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            P F +KL+   VA +G+ + L+C++S  P   + W  N   L  +    +S   S+  ++
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 6423

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            I +A  ED G Y C A N  G A CS  +TV         KAP + +++P          
Sbjct: 6424 INEASAEDSGDYICEAHNGVGDASCSTALTV---------KAPPVFTQKPS--------- 6465

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                           P  A+               G  V L  +++GT P    W+K RK
Sbjct: 6466 ---------------PVGAL--------------KGSDVILQCEISGTPPFEVVWVKDRK 6496

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            Q++ S+  K+ +    + L IL       G Y     N++GS     ++   + P
Sbjct: 6497 QVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 6551



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 103/475 (21%), Positives = 169/475 (35%), Gaps = 98/475 (20%)

Query: 993  AENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKP--MGNAKPAETL--K 1048
            A NG   A    A  V++  P+   +PS    PVG  K ++ +    +    P E +  K
Sbjct: 6439 AHNGVGDASCSTALTVKAP-PVFTQKPS----PVGALKGSDVILQCEISGTPPFEVVWVK 6493

Query: 1049 PMGNAKPDENLKSASKE--------ELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAF 1100
                 +  +  K  SK          L+     + +CK  +   +D    S      P F
Sbjct: 6494 DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRF 6553

Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIEK 1159
             +KL D     G  + L+  V    P +++W  + G+ ++ ++   +S   ++ ++ +  
Sbjct: 6554 VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGS 6613

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
                + G Y C  KNDAG  ECS  +TV +                              
Sbjct: 6614 PEASNSGKYICQIKNDAGMRECSAVLTVLE------------------------------ 6643

Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
                             P +II+ PE   V  G    L   VTGT  ++  W K  +++ 
Sbjct: 6644 -----------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELS 6686

Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1339
                  +      + L I  A     G Y+  V+N +G     V++ V D+  PP+    
Sbjct: 6687 ADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRK 6746

Query: 1340 ASDIR---------------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
              D+                S+ +++ W+    DG   V     +   S N        C
Sbjct: 6747 LKDVNAILGASVVLECRVSGSAPISVGWF---QDGNEIVSGPKCQSSFSEN-------VC 6796

Query: 1385 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKP--EEPKDEVEV 1437
               + N+  L P     +   A NV G+ E    S + TV E P  E+  D VEV
Sbjct: 6797 ---TLNLSLLEPSDTGIYTCVAANVAGSDEC---SAVLTVQEPPSFEQTPDSVEV 6845



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             +D P PPA    A D   SS+TL W    YDGGSAV  Y +EI     + W  ++T    
Sbjct: 27164 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 27222

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             R+T + V +L P   Y FRV A+N  G  EP + +E     +  E P+ +++V+
Sbjct: 27223 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 27276



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 63/276 (22%), Positives = 108/276 (39%), Gaps = 48/276 (17%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGY 59
            G     AS+   K S S        + + E P FI  L P  + +K+    ++E ++ G 
Sbjct: 7280 GQYTCYASNIAGKDSCSAQ------LGVQEPPRFIKKLEPSRI-VKQDEFTRYECKIGGS 7332

Query: 60   PEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            PE +V W+++   I    +F +   +     L +H +  ED G YTCEA N +G+   + 
Sbjct: 7333 PEIKVLWYKDETEIQESSKFRMSF-VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             L V+                                   PP F  K   +   +G    
Sbjct: 7392 SLKVKE----------------------------------PPIFRKKPHPIETLKGADVH 7417

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
              C++ G P   V+W K    L+   +  +  +N +  + I  V+  D+G Y C   N  
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477

Query: 240  GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
            G  +    ++++    A   FV++    ++ V KEV
Sbjct: 7478 GSDTCVGSIALK----APPRFVKKLSDISTVVGKEV 7509



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)

Query: 1266  PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
             P T  W++  K   +    +V+   N  K             + +L EN  G  +   + 
Sbjct: 13924 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 13972

Query: 1325  --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
               + + D  DPP   G P   D+  +S+ L+W    +DGG+ ++SY IE+  +    W  
Sbjct: 13973 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 14032

Query: 1381  LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
             +A    +T   +  L+   EY FRVRA+N  G SEPS+ S+     EK  P  P   +EV
Sbjct: 14033 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 14092



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+  +VA +   ++S+SV  + V+++     P F+   +N+ IKEG+  + + R  G P 
Sbjct: 1526 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1584

Query: 62   PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P + W +N   I      +  ++ G +G  +L I +   +D   YT  A N +G      
Sbjct: 1585 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643

Query: 120  ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
            ++ VE  FA+   +  +    G       +AP +E     +G              +  P
Sbjct: 1644 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1703

Query: 162  KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             F  KL  + +K      F C++T  G P   V WL    PL+ + R+ +  + G   L+
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1763

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
                   D G+ TC   N  G    SA L ++      +S V E++
Sbjct: 1764 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1805



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 46/249 (18%)

Query: 1098 PAFKQKLQD-VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            P+F ++L + V   EG    L+ +V+   P T+ W  N   ++ T    ++ + +   + 
Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQ 8308

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            + KA   D GLY C   NDAG A C+  + +                             
Sbjct: 8309 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVI----------------------------- 8339

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                        K P K   PP   Q      V  GE V+L   V G++PI   W+K  +
Sbjct: 8340 ------------KEPKK---PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 8384

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD-PPA 1335
            +I+ S+      +   + L +    +   G Y     N  GS   +  +T+ DKP   PA
Sbjct: 8385 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPA 8444

Query: 1336 GTPCASDIR 1344
                A D R
Sbjct: 8445 TKKAAVDGR 8453



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V V  G  + L+      P  +I W  +G  LK ++F+  S+  +  ++SI+ A  E  G
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 27632

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y  +  N        C++ V   P +  T  P  K + P                    
Sbjct: 27633 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 27663

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
                           I+F E +     +SV L   V    G   ITC  ++ R+  Q +  
Sbjct: 27664 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 27705

Query: 1284  MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
             M   + +    K+  L    E+   + +  EN+ G  Q  V+  +V K     P PP G 
Sbjct: 27706 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 27762

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
             P   ++ S  ++L+W    YDGGS V  + +E  +  +  W+++ T       +    L+
Sbjct: 27763 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 27822

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
                +Y+FRV A N  G S PS  S+  T+   P +P    +  D       V   T+T+ 
Sbjct: 27823 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 27874

Query: 1456  TEQKVSD------FYDIEERLGSGKF 1475
                 + D       Y IE+R G+ ++
Sbjct: 27875 WNPPLRDGGSKIVGYSIEKRQGNERW 27900



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 51/205 (24%), Positives = 79/205 (38%), Gaps = 32/205 (15%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
            G    FE R+ G    QV+W+++G  +      L    +    +L I    +   G+Y C
Sbjct: 7130 GFPVAFECRINGSEPLQVSWYKDGVLLKDDAN-LQTSFVHNVATLQILQTDQSHIGQYNC 7188

Query: 107  EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166
             A+N  G    + +L +                                  E PP F  K
Sbjct: 7189 SASNPLGTASSSAKLILSEH-------------------------------EVPPFFDLK 7217

Query: 167  LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
               V +  G+ G F C +TG    ++TW K N  ++P     ++       L +  V + 
Sbjct: 7218 PVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKG 7277

Query: 227  DVGVYTCLVVNGSGKASMSAELSIQ 251
            D G YTC   N +GK S SA+L +Q
Sbjct: 7278 DAGQYTCYASNIAGKDSCSAQLGVQ 7302



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)

Query: 2     GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
             G+V   A + I+   L+V    +D         F +P +++ + E   A+FE  +    E
Sbjct: 11464 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 11512

Query: 62    PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
               V W +    I S  +F +    +    LVI+    +D G YT E              
Sbjct: 11513 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 11557

Query: 122   TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
              VEG            K    R     +            KF + L    VKEG+   F 
Sbjct: 11558 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 11594

Query: 182   CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
             C+++   +  V W K +  L  S  V +S +     LE+  V  DD+      V     +
Sbjct: 11595 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 11649

Query: 242   ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
              S +A+L +   D      + +  A   D       V K+V     K+            
Sbjct: 11650 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 11709

Query: 284   KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
             K D L    K K      +G      G+    AN   +  R  K+E     P    +  V
Sbjct: 11710 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 11764

Query: 338   LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
              +     I L    V  + +  G  + +    E               Q G+ + +V  +
Sbjct: 11765 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 11823

Query: 398   AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
             AAN +      +    P     P S  +V E    KF CEVS  PK    W L+GT    
Sbjct: 11824 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 11880

Query: 457   QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
              +   E+ +D   H + +  A   D   Y   A +              +L +  +   F
Sbjct: 11881 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 11931

Query: 517   SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
              + LKD    E +  V    +    + R+ W  N Q +   RS        + +QD    
Sbjct: 11932 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 11982

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
                T+  L+ +   Q+   A            SE  L V       P F   L D   ++
Sbjct: 11983 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 12031

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
               +V +  ++S    P V W  +G EI+ S++   +  G +  L +++    D G YTC+
Sbjct: 12032 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 12090

Query: 697   AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
                  G  +T   L +++     +   +    SV     ++      I+ D     +W  
Sbjct: 12091 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 12141

Query: 757   DGKALCKDTGHFEVLQNEDVFTLVL 781
              G+AL + T   E+ +   + +LVL
Sbjct: 12142 KGEALLQ-TPDCEIKEEGKIHSLVL 12165



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)

Query: 1104  LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
             L  + V  G K+ L   V+  P   I WT     LK  K I +       +V+I  +   
Sbjct: 13697 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 13756

Query: 1164  DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             D G Y   A N  G+A    +V V D P                   PP     +D T +
Sbjct: 13757 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 13798

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                    PP+     +I  +  +++    E                 W K    ++++  
Sbjct: 13799 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 13842

Query: 1284  MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
                       K T L   +E+   + +  EN  G     Q + +T   + DPP G P   
Sbjct: 13843 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 13889

Query: 1340  -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
               SDI   ++TL+W     DGGS +  Y +E  D     W        + T++ V+ L  
Sbjct: 13890 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 13949

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
               +Y+FRV A N+ G  +PS+ +E   + +  + P
Sbjct: 13950 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 13984



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
            P F++ ++ + V+EGS A F+  I G+P PEV WF+D Q I  S     QI +  DG   
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L I  V   +  +Y+ KA N  G+AT TAEL+V+
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 51/223 (22%), Positives = 89/223 (39%), Gaps = 38/223 (17%)

Query: 26   SMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
            ++ + E P+F+  + P  L +  G +A+   +++G P  QVTW +N + ++      +  
Sbjct: 3730 TVTVREPPSFVKKVDPSYLMLP-GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF 3788

Query: 84   GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
             +     L I  V  ED G Y+CEA N  G+   + E+ ++                   
Sbjct: 3789 -VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------------------ 3829

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
                            PP F   L    +  G      C+++G    +++W K    ++ 
Sbjct: 3830 ----------------PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS 3873

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
            S +  +  +  +  LEI   N  DVG Y C+V N  GK    A
Sbjct: 3874 SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA 3916



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 61/269 (22%), Positives = 98/269 (36%), Gaps = 61/269 (22%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+F+Q    V V  G  L     +   PP  + W    + L   +   +S E  +  + +
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELEL 6893

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             +  P + G Y C+  NDAG A C+  + V +                            
Sbjct: 6894 FEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP--------------------------- 6926

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              AT  K+ A                  D  V  G  + L    TGT PI+ +W+K    
Sbjct: 6927 --ATFVKRLA------------------DFSVETGSPIVLEATYTGTPPISVSWIKDEYL 6966

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------ 1331
            I +SE   +  +E  + L IL +  E    Y+ L+EN+ G    +  ++V++ P      
Sbjct: 6967 ISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPL 7026

Query: 1332 -------DPPAGTPCASDIRSSSLTLSWY 1353
                     PA   C  D  +  + +SWY
Sbjct: 7027 EHVEAVIGEPATLQCKVD-GTPEIRISWY 7054



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)

Query: 1217  ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
             ESD  V + P      P TP   A+    +     + V  G S  +   +   +  +  W
Sbjct: 23410 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 23469

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
              K  K I      K +N E G +             + +  EN +G  +A  N       
Sbjct: 23470 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 23518

Query: 1332  DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
             DP  P GTP    ++ + +TL W    YDGGS +  Y +E  D  +  W + +      T
Sbjct: 23519 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 23578

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
              F V  L  D  Y+FRV A N  G  S+PS  +   T  ++ E P        +D + V+
Sbjct: 23579 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 23638

Query: 1439  DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
               +    E D     + T + +    +IEE          F+  L+ K   ++  G++  
Sbjct: 23639 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 23698

Query: 1496  KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
             +A +    ++    + +++    P+  VQ      EK ++     +  GG      + E 
Sbjct: 23699 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 23758

Query: 1555  FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
              E       +   E +    +++   EG EY+ +            IM VNK G
Sbjct: 23759 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 23800



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
             GC   Y +  EN  G         ++   DP     P   P   D   +++T++W    +
Sbjct: 26050 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 26109

Query: 1358  DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             DGG+ +  Y++E   S +  WK  + + R T + +  L    EY FRV+++N  G S+PS
Sbjct: 26110 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 26169

Query: 1417  QESELTTVGEKPEEPKDEVE 1436
               S+     E+ EEP  +++
Sbjct: 26170 DSSDPQIAKEREEEPLFDID 26189



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)

Query: 263   ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
             E     S  ++EVT +   E + +  + A +  + S+ +     R  SP +         
Sbjct: 32229 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 32288

Query: 311   --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
                S+PQP  E + ++ + SP     TP                +  PR+P     SP  
Sbjct: 32289 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 32323

Query: 369   EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
              ER      R A F   +R   + +     K + R+  +  Q+       P+   + +S 
Sbjct: 32324 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 32383

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              V   Q  +F   V   P  EV W+  G  ++ +   I     +G   L +L   T DSG
Sbjct: 32384 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 32442

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
             TY    +N +G+ S   TL V                       G D+    S R    V
Sbjct: 32443 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 32480

Query: 543   PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
             PR  +    +   YA S+       EA  +   ++  + E   + +    +A  ++  +A
Sbjct: 32481 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 32540

Query: 597   WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
                 ++ EK ++RK +  L        A   L     + V +G     +    G P P V
Sbjct: 32541 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592

Query: 655   IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
              WL  G  +  S          + +  I  V   D G Y+    NS G+   +  LT+Q+
Sbjct: 32593 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 32652



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             L  AP   L  R+  +  G   +F   V+  P  +V W+ NG  +    +        G 
Sbjct: 32370 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 32428

Query: 89    FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
              +L I   H +D G Y               T + T G               R V  EL
Sbjct: 32429 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 32488

Query: 122   TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
             T   ++A    K+  +   S ++ +   +   ETR S+                      
Sbjct: 32489 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 32547

Query: 158   ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                           +  TK   + V EG+  RFSC   G P P VTWL+    L  SAR 
Sbjct: 32548 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 32607

Query: 208   SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
              V+        EI  V   D G Y+ +V N  GK      L+IQ      ++ V E KA 
Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 32660

Query: 268   NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
              S  R     V S E ++ S EA    K   SP+    P       P   + +  E  + 
Sbjct: 32661 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 32711

Query: 328   SPRTAP 333
              P +AP
Sbjct: 32712 LPVSAP 32717



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)

Query: 1098  PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
             P    KL  V  V  G  + L+  V   P   + WT +      T+   + +        
Sbjct: 18201 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 18260

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
              S+ KA   D G Y   A N AG       V V D P    N K  ++ S R        
Sbjct: 18261 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 18312

Query: 1214  LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                    TV   P P+      +   I++  E +++                     W  
Sbjct: 18313 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 18345

Query: 1274  FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
             +   +             G+ +T L    E+   + +  ENK+G+     +  V+ K   
Sbjct: 18346 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 18393

Query: 1331  -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
                  PDPP  T  + +     +T+ W    YDGG ++  Y +E  +  +  W  +  + 
Sbjct: 18394 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 18449

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                    VQ+LLPDHEY+FRV+A N  G  EPS  S    V + P EP
Sbjct: 18450 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 18496



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 57/219 (26%), Positives = 88/219 (40%), Gaps = 35/219 (15%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P+FI   +++    GA+   E RV G     V W ++G  I SG +           +L 
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFS-ENVCTLN 6799

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            +  +   D G YTC A N +G+ + +  LTV+                            
Sbjct: 6800 LSLLEPSDTGIYTCVAANVAGSDECSAVLTVQE--------------------------- 6832

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
                   PP F      V V  G    F+  I G P  +V W KG+  L P    ++S +
Sbjct: 6833 -------PPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLE 6885

Query: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            + +  LE+  V   + G Y+CLV N +G AS +  L ++
Sbjct: 6886 DFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ +      +V   ++L +       P AT+ W  +G+TLK T  + +S   ++ S+SI
Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 25454

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++A  ED G Y+    N AG       + V D P                   PP     
Sbjct: 25455 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 25496

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              + +         PP+     QI  +  ++K                +  + TW    + 
Sbjct: 25497 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 25540

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
             +  +  +K+     GS+             + +  EN+ G      +  VV +    P  
Sbjct: 25541 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 25588

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
             P GTP       S++ ++W     DGGS V  Y +E       +W  ANK          
Sbjct: 25589 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 25643

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
             T   V  L     Y++RV A N+ G  + S+  E       P +P  + EV++   K   
Sbjct: 25644 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 25702

Query: 1447  VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
             + +     +   K++ +      L  G++
Sbjct: 25703 LKWSKPHYDGGAKITGYIVERRELPDGRW 25731



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)

Query: 1091  SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
             S+    APAF  + +  ++ EG+ +L  C++S +P   I W  N   +  +  + +S+  
Sbjct: 33127 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 33186

Query: 1151  SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
             ++ S+ I  A   D G Y   AKN  GQ   +  + V    + P+ E             
Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 33246

Query: 1195  --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
               ++++ +M + + ++S      + + +  + K A  +    +                 
Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 33306

Query: 1236  --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
                                 +PP+I   P D  +  G+ + +    TG      TW    
Sbjct: 33307 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 33366

Query: 1276  KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             ++I  QE     +EN+++ + L I+  +++  G YTL + N+ GS  A VN+ +
Sbjct: 33367 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 45/235 (19%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            AP  K+K++ + VA G      C++ S P     W   G+ +  +    +     + S+ 
Sbjct: 3455 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 3514

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            I +    D G Y C A N+ G   C+  +TV +A                          
Sbjct: 3515 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA-------------------------- 3548

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                                PP  +  P+      G++ +    VTGT  I   W K   
Sbjct: 3549 -------------------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 3589

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +  S + ++ ++EN   L +     +  G Y+    NK G+   Q  L ++DKP
Sbjct: 3590 ALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 12/162 (7%)

Query: 1693 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1747
            KW K G  + A     I   +++A +   S     +G  T  ++ E   S  + +   L+
Sbjct: 4049 KWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 4108

Query: 1748 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
                    + P+F+K +R+++ V     R DCKI G     V WFKD + I  S  ++I 
Sbjct: 4109 R------DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIA 4162

Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            + E G  SL I  V  +D   +TC+A NS+G    +  LIV+
Sbjct: 4163 FVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 60/273 (21%), Positives = 101/273 (36%), Gaps = 63/273 (23%)

Query: 1097 APA-FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            APA F ++L D  + +GK L+L+   +  PP ++ W  NG  +  ++   ++       +
Sbjct: 7866 APAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAIL 7925

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
             I  +  ED G Y C  +N +G+  CS Q+ + +                          
Sbjct: 7926 EIPSSTVEDAGQYNCYIENASGKDSCSAQILILE-------------------------- 7959

Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
                                 PP  ++  E  KV  G+S  L  ++ GT  I  +W K  
Sbjct: 7960 ---------------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGD 7998

Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
             +++ +   K+    N + L          G Y    EN +G   A   LTV ++  PP+
Sbjct: 7999 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPS 8058

Query: 1336 ------------GTPCASDIR---SSSLTLSWY 1353
                        G P   D     S  +++SWY
Sbjct: 8059 FSRQLRDVQETVGLPVVFDCAISGSEPISVSWY 8091



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
            S +  S A L   AE  P   P F + ++ + V +GS  R   ++ G P P V +++D  
Sbjct: 86   SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142

Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I+ S  FQI  + D   SL+I++   +D   Y+  A NS+G AT TAEL+V+  EE
Sbjct: 143  EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
            P   Q+LQ V V  GK       +S  P   I W    + L T    KF+   QE +L  
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            +   +A PED  +Y C AKND G A  S  ++V+          PE+ S  P   +P   
Sbjct: 3299 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3341

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP II   +D     G+      +V+GT  +  +W   
Sbjct: 3342 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3380

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             K+I+ S   ++   E+  +L I  A  E  G YT +  N +G   +  NL++
Sbjct: 3381 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)

Query: 1104  LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
             ++ + V  G  +     +   P  T  WT +G  +KT +   +  +     ++I+  L  
Sbjct: 17517 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 17576

Query: 1164  DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             D G Y+    N AG    +  +TV D P              P   +  +  T    T+ 
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 17624

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P    P      P I    E Q  R     + +G V+                     
Sbjct: 17625 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 17655

Query: 1284  MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
                    +GS  T L       GC   + +  ENK+G      +   V K    P  P G
Sbjct: 17656 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 17708

Query: 1337  TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
              P  +DI  ++ T+SW     DGGS +  Y +E       W   NKT           F 
Sbjct: 17709 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 17763

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             V  L   + Y+FRV A N+ G S+PS  S+
Sbjct: 17764 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 17793



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + L   V   P  T+ W  +G  LK  + I ++ + +LC++ +     +D G Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
                A+N +G    + ++ V D P    + K  +M S R   S  P L   G+E    +  
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 19426

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             K     P  A                         +V+ T PIT   ++  K I+  E+ 
Sbjct: 19427 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 19459

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
                                    + +  ENK G          + K   DPP     P  
Sbjct: 19460 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 19496

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
             S+I    +T+SW   + DGGS +  Y +E  ++    W ++        +     L    
Sbjct: 19497 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 19556

Query: 1399  EYKFRVRAINVYGTSEPSQESE 1420
             EY+FRV AIN  G  +PS  S+
Sbjct: 19557 EYEFRVTAINKAGPGKPSDASK 19578



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 48/235 (20%)

Query: 1098 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            P F +K   V V   G+    +CQ++  P   + W L+G  +   +   +S    L +  
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 4920

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            I  A  E+ G Y C A+NDAG A CS ++ V + P    T   E+K              
Sbjct: 4921 ISGARVENSGTYVCEARNDAGTASCSIELKVKEPP----TFIRELK-------------- 4962

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                                P +++++ +         VEL  +VTGT P   TW+K  +
Sbjct: 4963 --------------------PVEVVKYSD---------VELECEVTGTPPFEVTWLKNNR 4993

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +I+ S+   + +  +   L I        G Y  +V N+ GS      + + + P
Sbjct: 4994 EIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP 5048



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 47/261 (18%)

Query: 1074 DVNCKRGHAGTTDNEK---RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII 1130
            +  CK  ++  T + K   R + +   P+F ++L+D+    G  + L C+++   P  + 
Sbjct: 6148 EYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVC 6207

Query: 1131 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
            W  +G  L+  + +  S   ++ ++ I +      G Y C A N  G A  S ++T    
Sbjct: 6208 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT---- 6263

Query: 1191 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
                        +R PK S                            P     P    V 
Sbjct: 6264 ------------AREPKKS----------------------------PFFDIKPVSIDVI 6283

Query: 1251 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
            AGES +    VTG QP+  TW K  K+I+   +  +    N   L IL   +   G YT 
Sbjct: 6284 AGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTC 6343

Query: 1311 LVENKLGSRQAQVNLTVVDKP 1331
               N +G       L+V + P
Sbjct: 6344 QATNDVGKDMCSAQLSVKEPP 6364



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 43/237 (18%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F  +L  V    G+    +C V+   P  + W  + + +++     +S   +   +++
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTV 8212

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             K    D G Y C A N+ G+  C+ Q+ + +                    +PP     
Sbjct: 8213 LKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER------------------LIPPSFTKR 8254

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
               TV++                           G S +L G+V G+QPIT  W K   +
Sbjct: 8255 LSETVEETE-------------------------GNSFKLEGRVAGSQPITVAWYKNNIE 8289

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
            IQ + + ++    N   L +  A     G YT  V N  GS     ++ + +   PP
Sbjct: 8290 IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 8346



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)

Query: 1083  GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
             G +D    S+ Q      ++ L D+     K L+++   S          P   ++W+  
Sbjct: 26164 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 26223

Query: 1135  GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
                L+T  ++  +   S  S++IE A   D G Y    +N    A  +  V V D P   
Sbjct: 26224 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 26279

Query: 1195  NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
                             PP   T  D T +          A +   +   PE+        
Sbjct: 26280 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 26304

Query: 1255  VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
                     G  P+    ++ R   + S+   V  + N ++L+      +    Y   V  
Sbjct: 26305 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 26353

Query: 1313  ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             EN+ G     + +  + + +KP PP      S I   S++L+W    +DGGS +  Y +E
Sbjct: 26354 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 26412

Query: 1370  IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
               +   K W + A  +ST   V  L  + EY FRV A N  G S+P +      + E+ E
Sbjct: 26413 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 26472

Query: 1430  EPKDEVE 1436
              P+ +++
Sbjct: 26473 PPEIDMK 26479



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 60/253 (23%), Positives = 98/253 (38%), Gaps = 44/253 (17%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            + + E P F+  P++  +      + +  V G     + W ++ + + SG    +     
Sbjct: 4762 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 4821

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
             T SL + A    D G Y C+ +N  G       L     F K+                
Sbjct: 4822 ST-SLELFAAKATDSGTYICQLSNDVGTATSKATL-----FVKE---------------- 4859

Query: 147  PAVETRPSIWGECPPKFATKLGRVVV-KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
                         PP+F  K   V+V + GQ   F C+ITG P+ +V+W      +    
Sbjct: 4860 -------------PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQ 4906

Query: 206  RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            +  +S  +G+   +I G   ++ G Y C   N +G AS S EL ++       +F+RE K
Sbjct: 4907 KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK----EPPTFIRELK 4962

Query: 266  ATN----SDVRKE 274
                   SDV  E
Sbjct: 4963 PVEVVKYSDVELE 4975



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 15/113 (13%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P+F   +  ++ V G +A F+C + G    +V W KD + IR    +QI Y E+ +  L 
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLT 8211

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL--------------IVETMEEGEG 1856
            +  V   D  +YTC AVN +G+ +CTA+L              + ET+EE EG
Sbjct: 8212 VLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEG 8264



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             + +  GK L +   V+  P  T +WT     L   + +++   G+   + I+ AL +D G
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 15172

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y   A N  G    + +V V D P              P   L PV+ T     +    
Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 15218

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
              P+    + +   II+  +D K+            T  QPI            E+E  K 
Sbjct: 15219 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 15254

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
             +       +T L   QE+   + ++ +NK G     ++  +  VD   PP        ++
Sbjct: 15255 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 15305

Query: 1343  IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
                S++TL W     +GGS +Q Y IE        ++ +    C +TSF V++L     Y
Sbjct: 15306 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 15365

Query: 1401  KFRVRAINVYGTSEPS 1416
             +FRV+A+N  G SEPS
Sbjct: 15366 EFRVKAVNEIGESEPS 15381



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G+   L+  VS  PP T+ W+ +GK L+ T  + +       ++  + +   D G Y   
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 21535

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A N  G A+    V V D P              P      V    S+  V     P   
Sbjct: 21536 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 21582

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I+Q  E  ++                     W     ++Q ++         
Sbjct: 21583 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 21613

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
               K+T L    E+   + ++  NK G  +   +  V+       PDPP   P  + I   
Sbjct: 21614 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 21669

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ + W     DGGS + +Y +E  D A + W +    T     + V  L   HEY+FR+
Sbjct: 21670 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 21729

Query: 1405  RAINVYGTSEPSQES 1419
              A N  G S PS  S
Sbjct: 21730 MAENAAGISAPSPTS 21744



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +L EN+ G     +   ++   ++P PP G     D+  +S++LSW    +
Sbjct: 22016 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 22074

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             DGGS +  Y +E+    +  W   AT + T   +  L+   EY FRV A N  G S+P Q
Sbjct: 22075 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 22134

Query: 1418  ES 1419
              S
Sbjct: 22135 LS 22136



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PP+  P   D    S++L+W    YDGG+ +  Y +E+ +     W  +   AT R+T
Sbjct: 29342 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 29400

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
              F V DL    +Y FRV A+NV G SE S+        E+ E P  ++E++DD +K
Sbjct: 29401 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 29454



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 54/234 (23%), Positives = 84/234 (35%), Gaps = 44/234 (18%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F +KL+DVH   G  +  +C+++   P  + W  +G  LK    +  S   ++ ++ I
Sbjct: 7116 PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 7175

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             +      G Y C A N  G A  S ++ + +                            
Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-------------------------- 7209

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                              +PP     P    +  GES      VTGT PI  TW K  ++
Sbjct: 7210 ------------------VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNRE 7251

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            I+   + K+   EN + LT+L   +   G YT    N  G       L V + P
Sbjct: 7252 IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
             +AP F    RNL ++  + A    +V G+P+P V W+R G+ I + G ++ +     G  
Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 30985

Query: 90    SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
              L+I +V ++D   Y   ATN  G+   T  L VE      L                  
Sbjct: 30986 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 31027

Query: 150   ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
                        PK    +G V    G++       +G+P P +TW KG   +  +    V
Sbjct: 31028 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 31076

Query: 210   SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
                     L   +GV + D G Y     N  G    + EL +  +    R          
Sbjct: 31077 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 31130

Query: 269   SDVRKEVTNVISKESKLD 286
             SDV ++  N+   E   D
Sbjct: 31131 SDVSRDSVNLTWTEPASD 31148



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ K       +  G+ L ++  V   P   I W  +G+ LK T  + + +  +   + I
Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 24371

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y   A N AG A  +  V V + P                   PPV    
Sbjct: 24372 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 24413

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  +         PP      QI  +  +++                   T TW     
Sbjct: 24414 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 24457

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
              +  +  +K+   + G++             + +  EN+ G      +  V+      +P
Sbjct: 24458 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 24505

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
              PP GTP  + I    + + W+    DGG+ +  Y +E  +  +  W +L     + T F
Sbjct: 24506 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 24564

Query: 1390  NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 L    EY+F+V A N+ G  +PS+ SE     +  + P
Sbjct: 24565 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 24606



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)

Query: 9     SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
             S+ + + SL  + S    +  T A   +  PR++ + EG +A+F     G P P VTW R
Sbjct: 32538 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 32596

Query: 69    NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
              GQ +++  R  +     + TF   I +V   D G Y+    N  G ++    LT++ + 
Sbjct: 32597 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 32654

Query: 127   -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
                K +  P   K+   R  +P                       ET+P+       +  
Sbjct: 32655 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
               PPK    L     KE  + + +C +        +VTW K    L+ +         +G
Sbjct: 32715 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 32772

Query: 215   MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
                L+I+ + + D G Y C +    G +  + +   Q   S +    + ++   SD +  
Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 32832

Query: 275   VTNVISK 281
              + V  K
Sbjct: 32833 ESTVTRK 32839



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 52/224 (23%), Positives = 85/224 (37%), Gaps = 33/224 (14%)

Query: 29   LTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
            + + PA I+    L  +  G  A  E  V G PE +  W+++G+P+ +  ++ +      
Sbjct: 4012 IVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFK-NN 4070

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
               L  ++    D G+YT E +N  G+       T            V+ + +   F+ P
Sbjct: 4071 VAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFT------------VLDRDIAPFFTKP 4118

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                   + G C                   R  CKI G    +V+W K    +  S R 
Sbjct: 4119 LRNVDSVVNGTC-------------------RLDCKIAGSLPMRVSWFKDGKEIAASDRY 4159

Query: 208  SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
             ++   G   LEI  V+ +D G +TC   N  G    S  L +Q
Sbjct: 4160 RIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 69/307 (22%), Positives = 116/307 (37%), Gaps = 64/307 (20%)

Query: 1054 KPDENLKS------ASKEELKKDVKND--VNCKRGHA-GTTDNEKR--SESQGTAPAFKQ 1102
            + DENL++      A+ + L+ D+ +    +C   +  GT  +  R  +     +P F  
Sbjct: 6216 RDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDI 6275

Query: 1103 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1162
            K   + V  G+    +C V+   P  I W+ + K ++      ++  G+   + I K   
Sbjct: 6276 KPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK 6335

Query: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATV 1222
             D G Y C A ND G+  CS Q++V +                                 
Sbjct: 6336 GDSGQYTCQATNDVGKDMCSAQLSVKE--------------------------------- 6362

Query: 1223 KKKPAPKTPPKAAMPPQIIQFPEDQKV-RAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
                          PP+ ++  E  KV + GES++L  K++G+  I  +W +   ++ ES
Sbjct: 6363 --------------PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 6408

Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP-----DPPAG 1336
                +    + + LTI  A  E  G Y     N +G       LTV   P       P G
Sbjct: 6409 WKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVG 6468

Query: 1337 TPCASDI 1343
                SD+
Sbjct: 6469 ALKGSDV 6475



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 7/114 (6%)

Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
            E+ +D+ +A +  +        PYF + +  +E V G  A   CK++G P+  + W+K+ 
Sbjct: 7004 EAGQDICEALVSVLEP------PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEH 7057

Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +R +  +++ + ++   SL+I+ V   D  +Y+CKA NS+G    +A L+++
Sbjct: 7058 TKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G+++ +  +V G      TW K  K +   + + +       +L I  A +   G Y
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 17979

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              +  +N  G  Q    + V+D+P P       +++   + T+SW     +GGS + ++ +
Sbjct: 17980 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 18038

Query: 1369  EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
             E      K W  +A+  +      +LL ++EY FRV A N  G   P+ E++   +    
Sbjct: 18039 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 18097

Query: 1426  -EKPEEPKD 1433
              ++P EP++
Sbjct: 18098 IDRPGEPEN 18106



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)

Query: 1215  GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
             G +S+  V + P   P  PP    PP I+    D       SV L     K TG  PIT 
Sbjct: 20161 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 20209

Query: 1270  TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               ++F  R  +      K        K+T L    E+   + ++  N  G  +  +    
Sbjct: 20210 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 20267

Query: 1328  VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
             V   DP  P G P   +I  +S+TL W    YDGG  +  Y +E  D  +K+W +     
Sbjct: 20268 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 20327

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
                 +F V DL+   +Y+FR+RA N  G  S PS+ +E     ++ E P
Sbjct: 20328 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 67/331 (20%), Positives = 125/331 (37%), Gaps = 69/331 (20%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            +P F ++ + + V +   ++L  +V+  PP  I W  +   L++ +      +  L S+ 
Sbjct: 4392 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQ 4451

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            I K +  D G Y+C   N+ G + CS +VT+ +                           
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARVTLRE--------------------------- 4484

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                                PP  I+  E      G +      + G+ PIT TW+K   
Sbjct: 4485 --------------------PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----- 1331
            +I E +++++    N + L +     +H G Y    +N  G ++    L+V +       
Sbjct: 4525 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 4584

Query: 1332 ----DPPAGTPCASDIRSS---SLTLSWY--GSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
                D   G P    ++ S    +T  W+  G     GS    Y I + D+ +   K ++
Sbjct: 4585 AVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS---KYKISVTDTVS-ILKIIS 4640

Query: 1383 TCRSTS----FNVQDLLPDHEYKFRVRAINV 1409
            T +  S    F VQ+ +     K R+  +++
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDL 4671



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 14/163 (8%)

Query: 1693 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1747
            KW K G  +       I    +++++  +S  K  +G  T        E + DV ++  +
Sbjct: 4611 KWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT-------FEVQNDVGRSSCK 4663

Query: 1748 A-VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
            A +      + P F+K ++ ++ ++GS    +C + G     + WFKDDQ I  S  ++ 
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723

Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +  D    L IS + G D   YTC A N  G   C+  L V+
Sbjct: 4724 SF-HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 53/230 (23%), Positives = 85/230 (36%), Gaps = 44/230 (19%)

Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1161
            +K + V V E   + L+C V+  P   + W  +GK +  +++  +S E ++ S  I+  +
Sbjct: 5145 EKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVM 5204

Query: 1162 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1221
             +D G Y    +ND G + C   + V D                   ++PP        T
Sbjct: 5205 KQDSGQYTFKVENDFGSSSCDAYLRVLD------------------QNIPP------SFT 5240

Query: 1222 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
             K     K                      G S+ +  KV+G+ PI+  W K  K+I  S
Sbjct: 5241 KKLTKMDKV--------------------LGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280

Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
               ++   E    L +     E    YT  V N  G       LTV + P
Sbjct: 5281 AKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPP 5330



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +  EN+ G     Q    + V + P PP G     D+  +S++LSW    +
Sbjct: 23098 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 23156

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             DGGS +  Y +E+    ++ W E A  +S    + +L    EY FRV A+N  G S+P
Sbjct: 23157 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 23214



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 87/403 (21%), Positives = 150/403 (37%), Gaps = 89/403 (22%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+ +LV   HI+   L+V             PA+    +++ +KEG T     +    P 
Sbjct: 8725 GNYRLVCGPHIASAKLTVIE-----------PAWERHLQDVTLKEGQTCTMTCQF-SVPN 8772

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
             +  W RNG+ +   GR   +   +    L I  V  ED+G+YTC+  +     + + EL
Sbjct: 8773 VKSEWFRNGRILKPQGRHKTEVEHK-VHKLTIADVRAEDQGQYTCKYED----LETSAEL 8827

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
             +E                                   P +F  ++  +VV E Q   F 
Sbjct: 8828 RIEAE---------------------------------PIQFTKRIQNIVVSEHQSATFE 8854

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV-VNGSG 240
            C+++      VTW KG   L  S + +         + IH V  DD GVY+ +  +   G
Sbjct: 8855 CEVS-FDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 8913

Query: 241  KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
            +A  +AEL +                T  +++ E+      +S++       ++      
Sbjct: 8914 EARSTAELYL----------------TTKEIKLELKPPDIPDSRVPIPTMPIRA------ 8951

Query: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
                 PP        PP    L + ++     P    ++ T  ++   A +V  +P+   
Sbjct: 8952 ----VPPEEIPPVVAPPIPLLLPTPEEK---KPPPKRIEVTKKAVKKDAKKVVAKPKE-- 9002

Query: 361  LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
               ++P  E  K+P PP     P + P +   DV SKA   +I
Sbjct: 9003 ---MTPREEIVKKPPPP-TTLIPAKAPEI--IDVSSKAEEVKI 9039



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
             S+ TV + P  K P     P   +   +  +V+  E +   G +V G      +  +  W
Sbjct: 22329 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 22387

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +K  K        K    E G +     + +   G         +G         V   P
Sbjct: 22388 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 22438

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
               P G P A  +  +S+TL W   +YDGGS +  Y +E  +     W + +      T F
Sbjct: 22439 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 22498

Query: 1390  NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
              V  L+ DH Y+FRV A N  G  SEPS+ +   T  ++ + P+
Sbjct: 22499 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 22542



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L+  +S  P  TI W  + K L+T   + +     L S+ I+ A   + G Y+  
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 26946

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G A  + +V + D P              P   +     T    T+  +P P   
Sbjct: 26947 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 26993

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I++  E  +V                     W         SEH++    E 
Sbjct: 26994 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 27023

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
                 T +    E+   + +   NK G  +   + +VV K     P PP G P  + I  +
Sbjct: 27024 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 27080

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+ W     DGGS +  Y +E  D  +  W ++   T R T   V  L  + +Y++RV
Sbjct: 27081 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140

Query: 1405  RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
              A+N  G    S+ SE     +   P  P  ++ ++D
Sbjct: 27141 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 27177



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 33/95 (34%), Positives = 48/95 (50%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P   + I+   V +GS A F  ++ G PDPE  W+K+   I  S      + ED  C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            I DV  +D A    KA+N  GE +  A L+V+  +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
             P  P   P   D   SS++L W   + DGGS ++ Y +E+ +     WK        + T
Sbjct: 15704 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 15763

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
             C     N+++L    +Y+FRV+A+N  G SEPS  +      +  EEP+  +++   D
Sbjct: 15764 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 15818



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
             + KP PP   P A D   +S+ L+W    +DGGS +  Y +E     ++ W+       +
Sbjct: 17110 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 17168

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
             C  T + V  L     YKFRV A+N  G S+P+   E   V ++ E P+
Sbjct: 17169 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 17217



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)

Query: 1006  KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
             K V +S PLS   P   L+     K + TL           L P+  G AK D  + S  
Sbjct: 18788 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 18838

Query: 1064  KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
             +EE   D   + +  +  +    G  + +K                 E++G   A +Q L
Sbjct: 18839 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 18898

Query: 1105  -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
                    + + +  GKKL ++  V   P  T  W      + T+  + + +  S   + I
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 18958

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
             +    +D G Y   A+N +G      +V V DAP                   PP  +  
Sbjct: 18959 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 19003

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
              ++DA       P     + +   I+   E   V  G+ V     VT T        +  
Sbjct: 19004 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 19054

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
             K I   E++    +EN              G    L   K+    AQ    V  +P    
Sbjct: 19055 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 19099

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
              T    D     + ++W     DGGS +  Y IE       +W  AN T       RST 
Sbjct: 19100 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 19150

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
             +    L+   EY FR+ A+N  G+S PS+ +E  T    P +P  + EV D
Sbjct: 19151 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 19200



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)

Query: 45    KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +EG   K+  ++  Y +  QVTW+   + + +  ++ +     G   L +  + + D G 
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 31638

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
             Y C+  N  G      EL V+G   +++      +T+  +      +T   +  E PP+F
Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 31692

Query: 164   ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
                L       G+  RF   IT  P+P VTW K    ++P     + +     G+  L I
Sbjct: 31693 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 31752

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             + V  DD   YT +  N  G+ S  A+L++
Sbjct: 31753 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)

Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
            D EK+ +     P FK+KL  + +        +C+++   DP   + W  +GK L+    
Sbjct: 1696 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1750

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
            + +  E   CS+    A   D G+  C A N  G    S  + V D    E +   E + 
Sbjct: 1751 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1806

Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
               +  L  +   E  A         T  K    P I+ +PE  +V  GE+     +VTG
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866

Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
                   W    + I++S+  +V   +    L I+  +    G   +  EN  G  + +V
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1925

Query: 1324 NLTVVDKPD 1332
             L +  + D
Sbjct: 1926 KLEIQQRED 1934



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 54/228 (23%), Positives = 80/228 (35%), Gaps = 35/228 (15%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            L E P F+    +L    G T   +  VRG     VTW +  + I   G+  +     G 
Sbjct: 3920 LKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGV 3978

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              L+I  V     GKYTC A N +G++    EL V+                        
Sbjct: 3979 AVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE----------------------- 4015

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
                       P K   +   + V  G        + G P+ +  W K   PL  S +  
Sbjct: 4016 -----------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4064

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256
            +S KN +  L+ +     D G YT  + N  G +S     ++   D A
Sbjct: 4065 ISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIA 4112



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 58/246 (23%), Positives = 97/246 (39%), Gaps = 46/246 (18%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            L E P+FI    +     G TA F+  ++G     VTW ++   IT       D  IR T
Sbjct: 4482 LREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE------DDNIRMT 4535

Query: 89   F-----SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
            F     SL +  +  +  GKY C+A N +G ++ +  L+V+                   
Sbjct: 4536 FENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK------------------- 4576

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
               PA  T  ++              + V +G       K +G  +    W K    L  
Sbjct: 4577 --EPATITEEAV-------------SIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTL 4621

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
             ++  +S  + + +L+I    + D G YT  V N  G++S  A +++  L     SF ++
Sbjct: 4622 GSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-IIPPSFTKK 4680

Query: 264  TKATNS 269
             K  +S
Sbjct: 4681 LKKMDS 4686



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 57/244 (23%), Positives = 86/244 (35%), Gaps = 35/244 (14%)

Query: 24   VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
            V ++ L E P F+    +L +  G  A+ +  + G     V W +  + +      +   
Sbjct: 5601 VCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRIT 5660

Query: 84   GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
             +    +L        + GKY C+  N  G R+    L V                    
Sbjct: 5661 FVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV-------------------- 5700

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
               PAV                K G + V  G+     CK+ G P+  V W K    L  
Sbjct: 5701 -LEPAV-------------IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTS 5746

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
            S +   S  N +  L I  V + D G YT  V N  GK+S +A + +    +   SF R 
Sbjct: 5747 SQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSD-RAVPPSFTRR 5805

Query: 264  TKAT 267
             K T
Sbjct: 5806 LKNT 5809



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
             KP PP   P   DI  SS+ LSW    YDGG  +Q Y +E  D +   W           
Sbjct: 22837 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 22895

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             T+  V+ LL  HEY FR+ AIN  G  E +       V EK E P  ++++
Sbjct: 22896 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 22946



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 53/248 (21%), Positives = 95/248 (38%), Gaps = 47/248 (18%)

Query: 1099 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
            AF ++L D  V  GK ++L+   +   P ++ W  +G  + T++   +      C + I 
Sbjct: 5987 AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEIL 6046

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
             +   D G Y C  +N+AG+  C   V+  +                     PP   TE 
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGALVSTLE---------------------PPYFVTEL 6085

Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
            +           P +AA+               G+SV L  +V GT  IT +W K   ++
Sbjct: 6086 E-----------PLEAAV---------------GDSVSLQCQVAGTPEITVSWYKGDTKL 6119

Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
            + +   +   + N + L          G YT   EN +G+  ++    + ++  PP+   
Sbjct: 6120 RPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFAR 6179

Query: 1339 CASDIRSS 1346
               DI  +
Sbjct: 6180 QLKDIEQT 6187



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R    I GRP P+VTW K N+ L+  A +  +E     +L I   N+ D G
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 20843

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
              +   + N +GK   S  ++++ LD+      +R T  T   V              +TN
Sbjct: 20844 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 20901

Query: 278   VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
              I ++   ++     A  K   C+    G S          A N     +P   ++    
Sbjct: 20902 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 20961

Query: 326   KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
              ++P       ++  T S+++L      P+P+  G   ++    E +R    +  T  T 
Sbjct: 20962 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 21016

Query: 386   QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
               GL               Q +   +A R  P E      +  +  P+ + +   Q++  
Sbjct: 21017 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 21076

Query: 426   -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
              K    +K    V G PKP V W  +G  + +Q   +     A S  L + +    DSG 
Sbjct: 21077 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 21135

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
             Y  TA N  G++    T+QV  +      P  F  V  D
Sbjct: 21136 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 21174



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
             AP     +KD     G+   L C + G P+P I W   G+ +  +R    + +     L 
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591

Query: 570   IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
             +     ED G YTC+A N +G+V  S             S+ LL   P   P  P+  + 
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 30638

Query: 629   LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
                +    GS + + V   G P P + W H    +Q SE+   E       L ++ V  +
Sbjct: 30639 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 30694

Query: 689   -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
                G Y  +  N  G V   A+L V+      +P   + P  + A L  S +IS
Sbjct: 30695 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 30743



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            PP   + L  V V EG+     C I+G P P VTW + +  ++ S    ++ ++G+  L 
Sbjct: 942  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            I     +D G +TC  VN +G  S S  L++Q     +  F +ET A        VT   
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1049

Query: 280  SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
            + E K  ++S +      + +  Q G   P A
Sbjct: 1050 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1081



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
             +++      + V +       TI    + H   + ++ +NK G       + +    +  
Sbjct: 16256 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
              P  P   P  S +  +S+T++W    YDGGS V  Y +E+ D+ +K WK +      A 
Sbjct: 16316 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 16374

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 S+ V  L+   +Y+FRV AIN  G    S  S+  T  +    P
Sbjct: 16375 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 16422



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             + V  G+ + +  +V   P   I WT  GK L   K + L Q+     + I++A+  D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y   AKN +G A+ S  V V D P              P  +L     T+ + T+    
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 18021

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                            + P D                G   IT   +++RK  Q+   +  
Sbjct: 18022 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 18052

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
              +         L A  E+   + +  ENK+G      ++   + +  +D+P  P     A
Sbjct: 18053 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 18110

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
              D   + + L W    YDGGS   SY +E     +  W+ +   + + T + V   + + 
Sbjct: 18111 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 18169

Query: 1399  EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
              Y+FRV+  N  G S+  +  E+  V E  ++P  ++++S
Sbjct: 18170 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 18208



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
            T+  E   +++   P F Q+LQ + V +G ++ LQ +V+  P   + +  +G  ++++  
Sbjct: 90   TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
              +SQEG L S+ I +A PED G Y   A N  G+A  + ++ V   ++ PA +      
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
              +  E +  R +  +       S ATV+             K  P+ PPK    +  PP
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269

Query: 1239 QI 1240
             I
Sbjct: 270  SI 271



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            KP F       + +EG  ARFD K+ G P PE  WF D Q I      ++   EDG  SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            II      D  ++T  A N  G ++ +  L VE +E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1551



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 36/217 (16%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            E P+F+  P +  +  G+    +   +G     + W +  + + SGG   +      + S
Sbjct: 4204 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALES-S 4262

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L ++ V   D G YTC+ +N +G  + +  L     F K+                    
Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANL-----FVKE-------------------- 4297

Query: 151  TRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
                     P  F  KL    ++K+G   + +CK+TG P  ++TW   +  ++ S++  +
Sbjct: 4298 ---------PATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRM 4348

Query: 210  SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
            S      VL +  V  +D G Y C   N +G    S+
Sbjct: 4349 SFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSS 4385



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)

Query: 1308  YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
             + ++ EN  G  +       +  +D  DPP G P   +I   ++TL W    Y GG  + 
Sbjct: 21331 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 21389

Query: 1365  SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
             SY +E  D  N  W     +      F V  L  D  Y+FRV A N  G  S PS+ S+ 
Sbjct: 21390 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 21449

Query: 1422  TTVGEKPEEPKDEVEVSDDD 1441
              T  +  E PK +V+V   D
Sbjct: 21450 ITCRDDVEAPKIKVDVKFKD 21469



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PAFK       V  G+ L +       P   + W  +   LK T  +      +   ++I
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 22207

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A  ED G Y     N AG+A  +  V V D P                   PP    +
Sbjct: 22208 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 22249

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  T         PP               K   G S+  +  V      T TW     
Sbjct: 22250 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 22291

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
                         S   ++ TI A R +  GC   + +  EN+ G S       TV   P 
Sbjct: 22292 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 22338

Query: 1332  --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
                 P GTP  +     S+ + W     DGGS V  Y +E  +  +  W +L       T
Sbjct: 22339 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 22398

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F    L    EY+FRV A N+ G  +PS+ SE   V   P +P    E          +
Sbjct: 22399 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 22457

Query: 1448  DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
              ++  T +   K++ +   ++ L  G++
Sbjct: 22458 QWKKPTYDGGSKITGYIVEKKELPEGRW 22485



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P +K  +  VH  E  K+     +   P  TI W    + L  T  + +       S+S+
Sbjct: 22547 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 22603

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A+  D G Y   AKN AG+   +  V V D P       PE          P V+   
Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 22646

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
             S  T +K      PP       II +  +++    E+  L   V     Q ++C      
Sbjct: 22647 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 22696

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
                      KV     G++ T           + ++  NK G  +   +  VV K     
Sbjct: 22697 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 22736

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
             PD P   P  + +   S+ + W   + DGGS +  Y +E  D     W            
Sbjct: 22737 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 22795

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
               V  L+ +H+Y+FRV A N  G SEPS  S
Sbjct: 22796 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 22826



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W+K  K   +    K    + G +     + +   G         +G         V   
Sbjct: 24551 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 24601

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
             P  P G P A  I  +++TL W   +YDGGS +  Y +E  D  +  W +        T 
Sbjct: 24602 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 24661

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
             F V  L+ D  Y+FRV A N  G  SEPS  S   T  ++ + P   ++
Sbjct: 24662 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 24710



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
             AQ+  TV D P    G P  S+I  +S+TL+W     DGGS +Q Y +E  +  +  W +
Sbjct: 28145 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 28200

Query: 1381  LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
             + + R    T F V  L   +EY+F V A N  G    S  S L    E   P  P   V
Sbjct: 28201 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 28260

Query: 1436  EVSDDDEKEPEVDY 1449
             +V+D  +    +++
Sbjct: 28261 KVTDTSKTTVSLEW 28274



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            ++ G +AR  CK++G P  +V WFK+++ + ES   ++ Y  +    L I+DV  +D   
Sbjct: 3749 MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-YFVNSEAILDITDVKVEDSGS 3807

Query: 1829 YTCKAVNSLGEATCTAELIVE 1849
            Y+C+AVN +G  +C+ E++++
Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIK 3828



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 49/235 (20%), Positives = 90/235 (38%), Gaps = 48/235 (20%)

Query: 1098 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            P F +KL+   + + G    L+C+++  P   ++W  N   L  +    ++   S+  + 
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            +     ED G + C A+N AG   CS +V V + P                SS PP++ T
Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVF--------------SSFPPIVET 5528

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              +A                                  V L  +++GT P    W K ++
Sbjct: 5529 LKNA---------------------------------EVSLECELSGTPPFEVVWYKDKR 5555

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            Q++ S+  K+ +    + + IL       G Y    +N++GS      + + + P
Sbjct: 5556 QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 5610



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
             P  P   P  +D   SS++L+W    YDGG+ V+ Y +E+ ++A   W    TC      
Sbjct: 25002 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 25058

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
             +   F V  L  + EY FR+ AIN  G  EP+         E+ E P+ E++
Sbjct: 25059 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 25110



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             +HV  G+ + L   ++  PP    W   G  L+ ++ + +     +  ++I +    D G
Sbjct: 29748 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 29807

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
              Y    KN  G    + +V + D P                    P+   E DAT   + 
Sbjct: 29808 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 29852

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P P+    A +   +++  +  +          G +  ++ +T +  KF +  + +E+
Sbjct: 29853 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 29902

Query: 1284  MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             +            + A  +   G Y   +++++   ++ + +     P PP  T    D+
Sbjct: 29903 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 29943

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
                 +TL+WY    DGGS V  Y +E        W   NK    +   RST      L  
Sbjct: 29944 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 29998

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
               EY+ RV AIN  G+ +PS+ S+     +      KP+ P+
Sbjct: 29999 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 30040



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            +E P   P     ++D    EG  ARF C++ G  D +V W+  D+ I+ SR F++   E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
            D    L I++   +D+  YT  A N++G+ + TA L +E  E    E  E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 41/238 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F Q L  V V+EG+ + L C V    P  I W   G+ +K +     S       + +
Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLEL 8405

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                  D G Y C A N AG               S+ TK                    
Sbjct: 8406 RDVAKADSGDYVCKASNVAG---------------SDTTK-------------------- 8430

Query: 1218 SDATVKKKPA--PKTPPKAAMPPQIIQFPEDQKVRAGE--SVELFGKVTGTQPITCTWMK 1273
            S  T+K KPA  P T  KAA+  ++    E Q +R  E  +     KV G       W K
Sbjct: 8431 SKVTIKDKPAVAPATK-KAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 8489

Query: 1274 FR-KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             + +Q+ +   + +    + +KL I    +   G Y  +  N+ G  ++ VNL V ++
Sbjct: 8490 GKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 8547



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PPA  P   D   SS++LSW   +YDGGS +  Y +E+  + +  W         + T
Sbjct: 19589 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 19647

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
              F V  L+ D +Y+FRV A+N  G S+PS
Sbjct: 19648 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 19676



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)

Query: 1325  LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
             +   ++P PP       D   SS  L+W    +DGGS +  Y +E+    +  W E    
Sbjct: 28540 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 28598

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
             +  +F V+ L+   EY+FRV+A N  G SEP +      + E   EP
Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 28645



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P    + +    K  +  +  C++ G P P++ W+  G  +  Q    ++  D  +H L 
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 30591

Query: 474   LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             ++     D G Y+C A+N  G++  S  L ++  A  +  P +    K    + G    L
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 30648

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
                  G PVP +TW    + +Q + + T E      H+  ++   + H G Y     N  
Sbjct: 30649 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708

Query: 590   GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
             G V     V + +K             P KPT PI ++ L          +  +  +S  
Sbjct: 30709 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 30745

Query: 650   PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
             PP +    W+ N      E +E  ++         + C      E+ G Y    A N+ G
Sbjct: 30746 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 30805

Query: 703   ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
                 +   +V+ ++ P +  +P    KP ++TA        SC +A  P
Sbjct: 30806 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 30847



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 28    PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
             P++  P  +   ++  +   + AKF  +  G P P   W ++G+ IT GG++ L    +G
Sbjct: 32847 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 32905

Query: 88    TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
              F L IH     D G YTC   N +G+   + +LT++
Sbjct: 32906 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 72/302 (23%), Positives = 123/302 (40%), Gaps = 31/302 (10%)

Query: 313   QPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER- 371
             +P+P  E+++++ K  P     TP+    ++ +T+     + E +AP      P G  + 
Sbjct: 11020 EPKPKPEAEVKTIKPPPVEPEPTPI----AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKG 11075

Query: 372   --KRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQ 429
               K+   P  A     +PG G +    +A     P   Q  +   KF  + +   + E++
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEA-----PFTYQLKAVPLKFVKEIKDIILTESE 11130

Query: 430   TVK----FRCEVSGIPKPEVA-WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
              V     F C VS  P   +  W  +G+ +R +        D     L ++  +  D+G 
Sbjct: 11131 FVGSSAIFECLVS--PSTAITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGE 11187

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
             Y+C       + + +  L VE L V  V     ++ ++  V++GQ   L C +       
Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCELNKER--D 11241

Query: 545   ITWLLNGQPIQYARSTCEAGVA----ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
             + W  +G+ +         GV      L I DA   D GTYT   ENA   + CS+ V V
Sbjct: 11242 VVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKV 11300

Query: 601   HE 602
              E
Sbjct: 11301 VE 11302



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
             V KP PP G P   D   SS++++W    YDGGS +  Y +EI       W+ +   A  
Sbjct: 21753 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 21811

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             ++TS+ +  L  + EYK R+ A+N  G  EP+
Sbjct: 21812 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 21843



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W K  K +     MKV   + G               Y +  EN  G  +   +   V  
Sbjct: 25633 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 25681

Query: 1331  PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
              DP  P G P  ++I   S++L W    YDGG+ +  Y +E  +  +  W +      + 
Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 25741

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
             T F V +L  D  Y+FRV A N     SEPS+ +    V +  E P+  ++V   D
Sbjct: 25742 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 25797



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 52/241 (21%), Positives = 87/241 (36%), Gaps = 54/241 (22%)

Query: 1084 TTDNEKRSESQGTA------PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGK 1136
            T  NE  S S          P+F +K+   ++   G+   L C++   P   + W  N K
Sbjct: 3717 TASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNK 3776

Query: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1196
             L  +  + +    S   + I     ED G Y C A ND G   CS ++ + +       
Sbjct: 3777 ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------- 3829

Query: 1197 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256
                                                    PP  I+  E   +  G +  
Sbjct: 3830 ----------------------------------------PPSFIKTLEPADIVRGTNAL 3849

Query: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1316
            L  +V+GT P   +W K +KQI+ S+  ++ + ++   L I +      G Y  +V N++
Sbjct: 3850 LQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEV 3909

Query: 1317 G 1317
            G
Sbjct: 3910 G 3910



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 73/351 (20%), Positives = 128/351 (36%), Gaps = 64/351 (18%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+F +K++      G     Q  +    P T+ W  +   +     I ++ E ++ S+ +
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA----------------PASENTK---A 1198
                 +  G Y C AKNDAG   CS  ++V +                 PA+   K    
Sbjct: 4546 SGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGT 4605

Query: 1199 PEMKSRRPKSSLPPVLGTESDATV------------KKKPAP-----------KTPPKAA 1235
             E+ ++  K      LG++   +V            +KK +            ++  KA 
Sbjct: 4606 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 4665

Query: 1236 M-------PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
            +       PP   +  +      G  ++L   V G+ PI+  W K  ++I  SE  K   
Sbjct: 4666 INVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF 4725

Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP---DPPAGTPCASDIR- 1344
             +N + L I        G YT    NK G  Q   +LTV + P   + P       + R 
Sbjct: 4726 HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRV 4785

Query: 1345 --------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1387
                    ++ +T+ W+  + +  S     +  +W     T  EL   ++T
Sbjct: 4786 QLKALVGGTAPMTIKWFKDNKELHSGA---ARSVWKDDTSTSLELFAAKAT 4833



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            PYF K +  ++V  G +A   C++ G P+  V W+K D  +R +  +++ +  +   +L+
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLV 8019

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             + V  +D  +Y CKA NS+GE + +  L V+
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 2/128 (1%)

Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
            ++ G  +S  N   LE+ E +    +E   E +    P   + I  LEV  G  A+F C+
Sbjct: 3420 NAVGQVSSTANLS-LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478

Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
            I+  P+    WFK  + I ES    I   +  + SL I      D  +YTCKA N  G  
Sbjct: 3479 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSV 3537

Query: 1841 TCTAELIV 1848
            +CTA L V
Sbjct: 3538 SCTATLTV 3545



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 51/237 (21%), Positives = 86/237 (36%), Gaps = 44/237 (18%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F  +L+ +  A G  + LQCQV+  P  T+ W      L+ T         ++ ++  
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 6138

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             K    D G Y C A+N                                       +GT 
Sbjct: 6139 NKVNINDSGEYTCKAENS--------------------------------------IGTA 6160

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
            S  TV +        +  +PP   +  +D +   G  V L  ++ G+ PI   W +    
Sbjct: 6161 SSKTVFR------IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVL 6214

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
            +++ E+++    +N + L IL     H G Y+    N LG+  +   LT  +    P
Sbjct: 6215 LRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP 6271



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 4/157 (2%)

Query: 1693 KWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEE 1752
            KW K G  + +  +   ++  + +SG K    +P S       E +  V +    A  + 
Sbjct: 7618 KWFKDGKELTSDNKYK-ISFFNKVSGLKIINVAP-SDSGVYSFEVQNPVGKDSCTASLQV 7675

Query: 1753 KPH-VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
                V P F++ +++   + GS+   +CK+ G P   V WF +   I   R +Q     D
Sbjct: 7676 SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TD 7734

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              C+L ++ +   D   YTC A N  G   C+A L V
Sbjct: 7735 NTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 7771



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)

Query: 1131  WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
             W     T+K TK  +    EGSL              +++  A+N  GQ++ +    ++D
Sbjct: 14130 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 14173

Query: 1190  APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
             +  +++T           +  PP      D T +       PPK      I ++  ++K 
Sbjct: 14174 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 14224

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             R G                  W+K  K      + +V +   G+++      +   G   
Sbjct: 14225 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 14265

Query: 1310  LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
                   +G       +  ++ P  P   P     +D     + ++W     +GGS +  Y
Sbjct: 14266 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 14319

Query: 1367  SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
              +E+     + W  + +   +   F V++ ++PD EY  RVRA+N  G SEPS+ SE   
Sbjct: 14320 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 14379

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
               +   +P  ++E  D    E E     V +R V + T
Sbjct: 14380 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 14417



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G+   L+  V   P  TI W    K ++ +    +        + ++ A+  D G Y
Sbjct: 23637 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 23696

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
                A N AG       V V D P              P      V G  S+    K    
Sbjct: 23697 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 23739

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              +PP       I  +  +++    E+  L   V  ++ +T                    
Sbjct: 23740 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 23775

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
               N  K+T L    E+   + ++  NK G  +   +  V+ K     P PP      ++I
Sbjct: 23776 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 23830

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
                S+T+ W     DGGS +  Y +E  D +   W +    R T     V  L  DHEY+
Sbjct: 23831 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 23890

Query: 1402  FRVRAINVYGTSEPS 1416
             FRV A N  G  EPS
Sbjct: 23891 FRVSAENAAGVGEPS 23905



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 60/273 (21%), Positives = 100/273 (36%), Gaps = 48/273 (17%)

Query: 1061 SASKEELKKDVKNDVN--CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQ 1118
            +AS E ++ D+ +  N  C+  ++  + +   +      P+F  K     V  G  + L+
Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLK 4226

Query: 1119 CQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178
                   P TI W    K L +     +++E    S+ +      D G Y C   N AG 
Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG 4286

Query: 1179 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238
             ECS  + V                             +  AT  +K  P          
Sbjct: 4287 VECSANLFV-----------------------------KEPATFVEKLEP---------- 4307

Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
                    Q ++ G++ +L  KVTGT PI  TW    ++I+ES   ++   E+ + L + 
Sbjct: 4308 -------SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360

Query: 1299 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
                E  G Y    +N+ GS      + V + P
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 4393



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V E +  +F C ++   +  V W  +G  + +     ++  D   H L +  ++  D G 
Sbjct: 11497 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 11553

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
             Y+   +  +G+ + +      RL V  +   F S L+D  V EG+     C +    +  
Sbjct: 11554 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 11603

Query: 545   ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
             + W  N   +  +R+   +   + H  +           + E  L  +S      V E  
Sbjct: 11604 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 11651

Query: 605   SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
             S+ + + L          P F   L D   ++  ++T+  +VS + P  V W  +G EI 
Sbjct: 11652 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 11702

Query: 665   ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
              S  +  +  G +  L I++   +D G Y C+     G  +T+A +TV+      +   +
Sbjct: 11703 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 11753

Query: 725   SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
              KP   V   +G++      ++    P VH  W   G+ L   +   E++++     L+L
Sbjct: 11754 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 11809

Query: 782   KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
                Q    G+      N     + +V       +   S  +   +          REP +
Sbjct: 11810 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 11869

Query: 828   CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
                L G     +  G DR+  ++ G   +    ++    ED    +    +  +HT    
Sbjct: 11870 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 11922

Query: 885   --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
               E IR + +  L  +D+  K+    V T  LS D+++      + +  N QR    ++V
Sbjct: 11923 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 11974

Query: 939   S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
             S ++E K HS   + F+  L+   TS+  V                 +  + KL    G 
Sbjct: 11975 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 12017

Query: 998   S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
                + +  +   VE  + +   + S    PV   K  + +KP  NA              
Sbjct: 12018 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 12064

Query: 1056  DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
                +K+  K+    LKK +K+D+       GT     + + +       + L  V V E 
Sbjct: 12065 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 12121

Query: 1113  KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             +    + ++S D      W L G+ L  T    + +EG + S+ +     +  G
Sbjct: 12122 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 12174



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)

Query: 1090  RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
             R E      +   K +DV V   G+  +L+  +   P   ++W+ +GK L+ T   + + 
Sbjct: 24699 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 24758

Query: 1148  QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
                   ++ ++  +  D G Y     N  G       V V D P              P 
Sbjct: 24759 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 24805

Query: 1208  SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
                  V G  ++        P     A +   II+  E  ++                  
Sbjct: 24806 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 24847

Query: 1268  TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               +W +   ++Q   +          K+T L    E+   + ++  NK G  +   +  V
Sbjct: 24848 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 24893

Query: 1328  VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
                   KP  P  TP  S I   S+ ++W     DGG+ ++ Y +E  D     W +   
Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 24953

Query: 1382  ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
              T       V  L   H Y+FRV A N  G  EPS+ S
Sbjct: 24954 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 24991



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
             EAP      +++  K G  A+   ++ G P P + W+R G+ +    ++ +    R T +
Sbjct: 30531 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 30589

Query: 91    LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
             L +    +ED G YTC ATN  G  + + +L ++ +     G P+  K  G         
Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 30640

Query: 151   TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
                                     G   R      GRP P +TW  G   LQ S  +++ 
Sbjct: 30641 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 30678

Query: 211   EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
                    L +  V  +   G Y   + N  G      ++ IQ   D      V E    N
Sbjct: 30679 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 30738

Query: 269   SDV 271
             S V
Sbjct: 30739 SAV 30741



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
             +KP  P G P  + +   S  ++W   + DGG+ +++Y +E  +     W  + T   R 
Sbjct: 30823 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 30881

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
             T F+V++L+   EY+FRV+  N+ G SE S+ SE       P  PK +V +     KE
Sbjct: 30882 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 30932



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
             P FK+ L +    EG+ +  + +VS  PP T+ W  +G+ L     I +  EG    ++ 
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854

Query: 1157  IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
             I   LPED G Y+  A N AG   C   + V+      +  K+ E   R  +  +   L 
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 31914

Query: 1215  ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
                   GTES            +A V  KPA  T   K     +I +  E++K+R
Sbjct: 31915 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 31969



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 42/230 (18%), Positives = 82/230 (35%), Gaps = 47/230 (20%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+F ++L++     G   +L+C+V+   P ++ W      + +      +   ++C++ +
Sbjct: 5800 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 5859

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                  D G Y CVA N AG  EC   +TV + P+                         
Sbjct: 5860 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPS------------------------- 5894

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                                   ++ PE  +V  G++V     + GT P    W +  ++
Sbjct: 5895 ----------------------FVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARE 5932

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            + + +   +   +  ++L +        G YT +V N  G       L V
Sbjct: 5933 LVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 5982



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 55/284 (19%), Positives = 97/284 (34%), Gaps = 65/284 (22%)

Query: 1057 ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1116
            +N+ +     L      +  C   +   +D  +   +    P+F ++ + + V  GK + 
Sbjct: 5852 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVT 5911

Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE---------DRGL 1167
                +   PP  + W    + L          +G  C++  E  + E           G 
Sbjct: 5912 FTSVIRGTPPFKVNWFRGARELV---------KGDRCNIYFEDTVAELELFNIDISQSGE 5962

Query: 1168 YKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPA 1227
            Y CV  N+AGQA C+ ++ V +                                      
Sbjct: 5963 YTCVVSNNAGQASCTTRLFVKE-------------------------------------- 5984

Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
                     P   ++   D  V  G+S+ L    TGT PI+ TW K    I  SE   + 
Sbjct: 5985 ---------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIV 6035

Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +E    L IL + +   G Y+  +EN+ G       ++ ++ P
Sbjct: 6036 TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 6079



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 49/237 (20%), Positives = 84/237 (35%), Gaps = 44/237 (18%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F + L+ V    G+   LQC+V   P   I W      L++     +  + ++ S+ I
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 7079

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             K    D G Y C A N  G    S  + +              K+R+            
Sbjct: 7080 NKVDHSDVGEYSCKADNSVGAVASSAVLVI--------------KARK------------ 7113

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                              +PP   +  +D     G  V    ++ G++P+  +W K    
Sbjct: 7114 ------------------LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVL 7155

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
            +++  +++     N + L IL   Q H G Y     N LG+  +   L + +   PP
Sbjct: 7156 LKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 7212



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
            PYF       ++VEG +  F C++ G P P V W K    +     +++ Y+ + G C L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +IS    DD  +YT    N  GE + +A L+ E
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 50/233 (21%)

Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT---KFIILSQEGSLCSVSIE 1158
            +K   + V  G+   L+C+V+  P  ++ W  +GK L ++   KF   ++  SL  +S+E
Sbjct: 5708 EKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE 5767

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
            +   +D G Y    +N+ G++ C+  V V D                             
Sbjct: 5768 R---QDAGTYTFQVQNNVGKSSCTAVVDVSD----------------------------- 5795

Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
                            A+PP   +  ++     G S  L  KV G+ PI+  W   + +I
Sbjct: 5796 ---------------RAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKI 5840

Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
                  +   S+N   L + +      G YT +  N  GS + +  LTV + P
Sbjct: 5841 VSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 5893



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 51/227 (22%), Positives = 84/227 (37%), Gaps = 41/227 (18%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            + + E P+F   P ++ +  G +  F   +RG P  +V W +  + +  G      C I 
Sbjct: 6828 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGE----SCNIS 6883

Query: 87   ---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
                   L +  V   + G Y+C  TN +G+   T  L     F K+             
Sbjct: 6884 LEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHL-----FVKE------------- 6925

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
                            P  F  +L    V+ G         TG P   V+W+K    +  
Sbjct: 6926 ----------------PATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQ 6969

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            S R S++      +LEI     +D   Y+CL+ N +G+    A +S+
Sbjct: 6970 SERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSV 7016



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + ++ EN+ G       +  V   +PP+  G    +D+  +S +L W    +DGGS V  
Sbjct: 24187 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 24246

Query: 1366  YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             Y +E+     + W  +A  +  +  V  L    EY+FRV+A N  G S+P
Sbjct: 24247 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 24296



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)

Query: 1739  EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
             ED  +A L       P    ++P F + + + E  EG +  F+ ++ G P P + W KD 
Sbjct: 31773 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832

Query: 1796  QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
             Q +    + +I ++     +L I D   +D   Y   A N+ G  +C A L VE +   +
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892

Query: 1856  GEGEEEEE 1863
              E + +EE
Sbjct: 31893 QEFKSKEE 31900



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
            P   + ++ + V  G  ARF   I G P P++ W+K++Q +  S  F+  +  DG   +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            ++ +   +D A YTC+A N  G AT +A L VE  E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 47/237 (19%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F +K+ D+    G+ + LQ  V    P ++ W    + ++    I +S    +  + I
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 3983

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                    G Y C+A+N+AG      Q +V +    E                       
Sbjct: 3984 PDVQISFGGKYTCLAENEAGS-----QTSVGELIVKE----------------------- 4015

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                               P +II+  E  +V AG+   L   V GT  +   W K  + 
Sbjct: 4016 -------------------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4056

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
            +  S+  ++    N ++L   +A     G YT  + N++GS   +   TV+D+   P
Sbjct: 4057 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 4113



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 2/93 (2%)

Query: 1758 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            P F K +   +V  +G + + +CKI G P+ +V WF++D  + ES  + + +  +    L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             I++   +D   Y C+A N +G+A+C+  L V+
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F K    +E ++G+    +C+++G P   V W+KD + +R  + ++I   E+   S+ 
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIH 7457

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I +V   D  +Y CKA N +G  TC   + ++
Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             V KP PP       D   +S+TL+W    YDGGS +  Y +EI  +  + W+ +      
Sbjct: 23917 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 23975

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
             R T F +  L    EYK RV A+N  G  E +  S   TV  KPE+  +  E+  D E
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 24029



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)

Query: 1302  QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
             QE C  Y  +L  N+ G    A+    V V +P  P G     D+  ++ T+ W     D
Sbjct: 25263 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 25322

Query: 1359  GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GGS +  Y +E+    ++ W      ++    +  L    EY FRV A+N  G S+P Q
Sbjct: 25323 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 8/160 (5%)

Query: 1693 KWQKTGNAVRAIGRLSSMAMISGLSG-RKSSTGSPTSPLNAEKLESEEDVSQ--AFLEAV 1749
            KW K G  +    R  SM+  + ++  R  S     S     K+E++   S   A+L  +
Sbjct: 5173 KWLKDGKQI-VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL 5231

Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
             +  P   P F+K +  ++ V GS+   +CK+ G       WFKD + I  S  +++   
Sbjct: 5232 DQNIP---PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288

Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            E  + SL ++++  +D A YTCK  N  G+  C+  L V+
Sbjct: 5289 E-RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            PYF   +  LE   G +    C++ G P+  V W+K D  +R +  ++  Y  +   +L+
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLV 6137

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEAT 1841
             + V  +D  +YTCKA NS+G A+
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTAS 6161



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 55/269 (20%), Positives = 96/269 (35%), Gaps = 62/269 (23%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F ++L D  V  G  ++L+   +  PP ++ W  +   +  ++   ++       + I +
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
            +  ED   Y C+ +N+AGQ  C   V+V +                              
Sbjct: 6989 STIEDYAQYSCLIENEAGQDICEALVSVLE------------------------------ 7018

Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
                             PP  I+  E  +   GE   L  KV GT  I  +W K   +++
Sbjct: 7019 -----------------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7061

Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----- 1334
             +   K++   N + L I        G Y+   +N +G+  +   L +  +  PP     
Sbjct: 7062 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARK 7121

Query: 1335 -------AGTPCASDIR---SSSLTLSWY 1353
                    G P A + R   S  L +SWY
Sbjct: 7122 LKDVHETLGFPVAFECRINGSEPLQVSWY 7150



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 2/93 (2%)

Query: 1758 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            P F K +    +V +    R++CKI G P+ +V+W+KD+  I+ES  F++ +  D    L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVL 7363

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             + ++  +D   YTC+A N+ G A+ +  L V+
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 50/225 (22%), Positives = 79/225 (35%), Gaps = 32/225 (14%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            + + E    I  P  + +  G     E  V G PE    W ++G+ +++  +  +   I 
Sbjct: 6639 LTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITF-IN 6697

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
               SL I      D+G Y+ E  N  G    TV + V                  DR   
Sbjct: 6698 KVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS-----------------DRI-- 6738

Query: 147  PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
                         PP F  KL  V    G      C+++G     V W +    +    +
Sbjct: 6739 ------------VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPK 6786

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               S    +  L +  +   D G+YTC+  N +G    SA L++Q
Sbjct: 6787 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 53/224 (23%), Positives = 87/224 (38%), Gaps = 41/224 (18%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            E   F+    +  ++ G+    E    G P   V+W ++   I+   R    C I  T  
Sbjct: 6925 EPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSER----CSITMTEK 6980

Query: 91   LVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
              I  + E   ED  +Y+C   N +G               + + + +VS          
Sbjct: 6981 STILEILESTIEDYAQYSCLIENEAG---------------QDICEALVS---------- 7015

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
             +E         PP F   L  V    G+     CK+ G P+ +++W K +  L+ +   
Sbjct: 7016 VLE---------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAY 7066

Query: 208  SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
             +  KN +  L I+ V+  DVG Y+C   N  G  + SA L I+
Sbjct: 7067 KMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + +   VS  PP T+ W +N +TL     I  +   S  S+ I+      +G+Y
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 16593

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
               +AKN+AG+ + +  V V D P    T  P +       S                   
Sbjct: 16594 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 16633

Query: 1229  KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
                       ++  F PED                G  PIT  ++  +++        V 
Sbjct: 16634 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 16667

Query: 1288  NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
              +      T+    Q     + +  EN +G      + +A V    +  P+ P       
Sbjct: 16668 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 16726

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
             ++  +++TL+W    YDGGS + +Y +E      + + ++      S  + V+ L     
Sbjct: 16727 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 16786

Query: 1400  YKFRVRAINVYGTSEPS 1416
             Y++RV A+N+ G  +PS
Sbjct: 16787 YEYRVSAVNIVGQGKPS 16803



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + ++  V   P  T+ W    + LK T+ +      +   ++I + +  D G Y   
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A+N  G+      + V D P                   PP    + D            
Sbjct: 21140 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 21170

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                 +    + F  D     G        V   Q  + TW++    +       +  +  
Sbjct: 21171 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 21219

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
              ++LT     Q     + +  +N+ G      +  +V       P PP GTP  + +   
Sbjct: 21220 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 21273

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+SW+    DGGS +  Y +E  +     W+ +  A      F    L     Y+FRV
Sbjct: 21274 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 21333

Query: 1405  RAINVYGTSEPSQESE 1420
              A N+ G S+PS+ SE
Sbjct: 21334 IAENMAGKSKPSKPSE 21349



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)

Query: 1057  ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
             E L   ++ E +   KND        A ++   K  + + TA       Q +    G   
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 28665

Query: 1116  LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
              +   +S  P   + W L    LK T  + ++      +++++ ++  D G Y    +N 
Sbjct: 28666 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 28725

Query: 1176  AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
             AG    S  V V   P              P +    V    +++ V     PK      
Sbjct: 28726 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +   I++  E                      T  W      ++ ++           K+
Sbjct: 28773 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 28802

Query: 1296  TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
             T L    E+   + +  EN+ G S+  +    + + P  P   P   +   + ++++++ 
Sbjct: 28803 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 28860

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             W    +DGGS +  Y +E  +     W  +    C   ++ V  L+   EY+FR  A+N 
Sbjct: 28861 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 28920

Query: 1410  YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
              G S+ S+ S    + + P +     EV+D
Sbjct: 28921 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 28949



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F++    +  ++GS     C+I G P  EVVW KD + +R S+ F+I   +  + SL 
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLH 6516

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
            I ++   D  +Y CKA N +G  TC+  +
Sbjct: 6517 ILNLEASDVGEYHCKATNEVGSDTCSCSV 6545



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%)

Query: 1740 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
            +VS +    V E+K  + P FS+ +RD++   G    FDC I G     V W+KD + ++
Sbjct: 8041 EVSASTFLTVQEQK--LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098

Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +S + Q  +  D   +L I         +Y+C A N +G A+ +A LI+
Sbjct: 8099 DSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
             P  P   P  +D    S +L+W    YDGG  +  Y +E     ++ W +  T    R T
Sbjct: 20672 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 20731

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F V DL    +Y FR+ AIN  G  EP+   ++  V         E E++ D E + E+
Sbjct: 20732 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 20782

Query: 1448  DYRTVTINTEQKVSDFYDIEER 1469
               RT+ +     +  F  I+ R
Sbjct: 20783 -RRTLVVRAGLSIRIFVPIKGR 20803



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)

Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
            P      +++E  E ++   A      ++K   KP        + V+EG  ARF C++ G
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866

Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
            YP P+V W+ + Q IR+S+ F++ Y  DG   L I D    D  +    A N  G     
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1924

Query: 1844 AELIVETMEE 1853
             +L ++  E+
Sbjct: 1925 VKLEIQQRED 1934



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
             GC   + ++ EN+ G  +       V   + P PP       DI  S+++L+W    +DG
Sbjct: 20934 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 20992

Query: 1360  GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             GS +  Y IE     +  W  + T +     V++L    EY F+V A+N  G S P +ES
Sbjct: 20993 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 21051

Query: 1420  ELTTVGEKPEEPK 1432
                 V E+   P+
Sbjct: 21052 RPVIVKEQTMLPE 21064



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
            AP F Q LQ V V EG     +  +S  P   + W  +G+ + T+    + +S       
Sbjct: 5    APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            ++I      + G Y   A N +GQA  + ++ V    A                      
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP  +Q  +   VR G  V L  +VTG       + + 
Sbjct: 103  ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
              +IQ S   ++    +   L I  A  E  G Y++   N +G   +   L V  + + P
Sbjct: 141  GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200

Query: 1335 A 1335
            A
Sbjct: 201  A 201



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F    + L    G AA+F C + G P  E +W KD  ++  S +++I  D +    L 
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS-DAENKHILE 3609

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +S++   D   Y+CKA N  G   C AELI+
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII 3640



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 67/319 (21%), Positives = 123/319 (38%), Gaps = 53/319 (16%)

Query: 1082 AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT 1141
            + + D   R   Q   P+F +KL  +    G  + ++C+VS   P +  W  +GK + T+
Sbjct: 5221 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280

Query: 1142 -KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
             K+ ++  E S+ S+ +     ED   Y C   N AG   CS  +TV + P S   K P 
Sbjct: 5281 AKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-PPSFLVK-PG 5337

Query: 1201 MKSRRPKSSL---------PP---------------------VLGTESDATVKKKPAPKT 1230
             +   P S++         PP                     + G+ S   +    A KT
Sbjct: 5338 RQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKT 5397

Query: 1231 PPKAAM------------------PPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTW 1271
                                    PP+ ++  E  K V+AG+S  L  K+ G+  I   W
Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457

Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +   ++  S+  ++   ++ + + +     E  G +    +N  GS      + V + P
Sbjct: 5458 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 5517

Query: 1332 DPPAGTPCASDIRSSSLTL 1350
               +  P    ++++ ++L
Sbjct: 5518 VFSSFPPIVETLKNAEVSL 5536



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 3/98 (3%)

Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
            +P   P+F      ++V+ G +A F+C + G     + W KD++ IR   ++ I     G
Sbjct: 6266 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC--VG 6323

Query: 1813 NC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            N   L I  V   D  +YTC+A N +G+  C+A+L V+
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 1754  PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
             P   P+F + +R+L V   S A   CK+ G+P P V W++  +  I +   ++I   + G
Sbjct: 30924 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 30983

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                LII+ V  DD   Y  +A N  G  + TA L VE
Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P F    R   + EG    F C+I G P PE+ WFK++  I  S +  I    +   SL 
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 33192

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I +    D  KYT KA N  G+ + TA L+V  + E
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 5/159 (3%)

Query: 1691 RRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
            R  W   GN + AI +   ++ I GL+  + S G+          E+  D   A      
Sbjct: 4892 RVSWYLDGNEITAIQK-HGISFIDGLATFQIS-GARVENSGTYVCEARNDAGTA--SCSI 4947

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            E K    P F + ++ +EVV+ S    +C++ G P  EV W K+++ IR S+ + +  D 
Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DR 5006

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                +L I+     D  +Y C   N  G  +C+  + ++
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P FS     +E ++ +    +C++ G P  EVVW+KD + +R S+ ++I   ++ + S+ 
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIH 5575

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATC 1842
            I +V   D  +Y CKA N +G  TC
Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVGSDTC 5600



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
             P PP   P  +D   SS  L W     DGGS V  Y +E  +   + W++      R T 
Sbjct: 16422 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 16479

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
               V  L     YKFRVRA+N+ G  EP + +++  + ++   P  +++ S  D
Sbjct: 16480 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 16532



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
             KP  P   P   D    +  L W     DGGS +  Y +E        W  +      R 
Sbjct: 17802 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 17861

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
              +F V  L+  +EY+FR++A N+ G  EP + +E     +    P+ E++V+  D
Sbjct: 17862 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
             TES   + K    K  P    PP++ +  +++        E  G   +TG      +  +
Sbjct: 18382 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 18439

Query: 1269  CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
               W+   K       MKV+N              +H   + +  EN++G  +  +    V
Sbjct: 18440 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 18488

Query: 1329  DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
                DP  P G P      D    S+TL W    YDGG+ +  Y +E+       S ++ W
Sbjct: 18489 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548

Query: 1379  KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             K     A      F V  L  + EY+FRV A N  G   P++  E     E  E P+ ++
Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608

Query: 1436  EVS 1438
             + S
Sbjct: 18609 DAS 18611



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
             D+  S++TL+W    YDGGS +  Y +E   +  + W ++ T + T     V  L    +
Sbjct: 29645 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 29704

Query: 1400  YKFRVRAINVYGTSEPSQESELTTV 1424
             Y FR+RA N  G SEP +     TV
Sbjct: 29705 YLFRIRAQNEKGVSEPRETVTAVTV 29729



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
             AP F   L++  V    +  L C V G P P + W   G+ I     +Y     + G  +
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I     +D   Y   A N  G VS +A + V                P+K   P  L+
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 31032

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
             G+  +  + G  V++ +  SG P P + W   G ++ ++   H++   T+    +  VFP
Sbjct: 31033 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 31088

Query: 688   -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
                  +D G Y   A N  G   +     V  V +P  G +   +S+       +  AS 
Sbjct: 31089 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 31148

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKA 760
             G S + +  +         WLR G+A
Sbjct: 31149 GGSKITNYIVEKCATTAERWLRVGQA 31174



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
             PDPP        I  +++ LSW     DGGS V  Y +E   WD   +  + W++     
Sbjct: 16012 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 16070

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
                  F V+DL+   EY+FRV+A+N  G S+PS      TVG    ++P+ P
Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 16117



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
             + G + K    + G P P + W+++ + + +     L C +  T  L    + + DR   
Sbjct: 26885 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 26940

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             G Y  +  N  G+   T+ + +        G P+  KT+         E    +W     
Sbjct: 26941 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 26992

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
                 K+   +V++ +  R    +      +        +KGN  +            +P 
Sbjct: 26993 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 27052

Query: 205   ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
                SV  KN        G+ +   +   +  VV     A   +++S   ++  D  +  +
Sbjct: 27053 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 27112

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
              +  K T  D R++VT +              + + C+    G  P        +P    
Sbjct: 27113 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 27158

Query: 321   KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
             K     D P    +  +   T SSITL  ++   +      G  V    GEE +      
Sbjct: 27159 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 27218

Query: 379   PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
                  T +       PG+     VS    A +  P+E             P+        
Sbjct: 27219 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 27278

Query: 422   -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
              S   K  + V+      G P P V W  +     +  GS   Y  E+  S  L  +   
Sbjct: 27279 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 27334

Query: 479   TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
             TR D+G Y  T  N  G+   S T+ V         ++L V  V+    ++L D  +I+G
Sbjct: 27335 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 27393

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
                ++   +      + TW +            +       + D   +    +  LAEN 
Sbjct: 27394 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 27444

Query: 589   LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
             +G                   E   PV  ++  API    + D               DG
Sbjct: 27445 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 27490

Query: 638   SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
               V     V      E  W H G  I ++ +    Q   Q  L  +     + G      
Sbjct: 27491 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 27547

Query: 698   WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
               + G +  + ++   E      P        VT  +G +V +     G P P++ WL+D
Sbjct: 27548 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 27600

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
             G  L K++      + E+  TL +K  +  H G+Y ++L N V  C   V + +      
Sbjct: 27601 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 27657

Query: 818   ALPRG 822
             + P+G
Sbjct: 27658 SKPKG 27662



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)

Query: 1308  YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + +  EN  G  S       T+   P  P GTP   D+   ++TL W     DGGS +  
Sbjct: 27829 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 27888

Query: 1366  YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
             YSIE     N+ W      +++ C+   + V  L P   Y+FR+ A N  GT S PSQ S
Sbjct: 27889 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944

Query: 1420  ELTTVGEKPEEP 1431
              +    ++   P
Sbjct: 27945 GIIMTRDENVPP 27956



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)

Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            +EAV  +   VKP F + ++++ + EGS      +  G P+P++VW K+   I   ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603

Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
            I  +   G  +L I      D A YT  A+N  G  T   ++ VE +E  E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)

Query: 388   GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
             G+ + +V  K  + R+ + G R     KF S  + Q VKE +T  F CE+S   K  V W
Sbjct: 11552 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 11606

Query: 448   FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
             F     +     ++ +  +  +H L + +    D                        +L
Sbjct: 11607 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 11656

Query: 508   AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
              V+E  P F+  L D   +E  +  L+C V    VP + W  +G+ I      S    G+
Sbjct: 11657 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 11714

Query: 566   AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
                L I+ A  +D G Y C      G     A VTV  +           +   KP    
Sbjct: 11715 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 11756

Query: 625   FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
                 L  ++V  G      +++S  P     W   G  +  S D    + G +H L +  
Sbjct: 11757 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 11811

Query: 685   VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
                  TG  + +A N+    ++ A L V+E        FI+    V           C +
Sbjct: 11812 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 11863

Query: 745   AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
             + +P  T  WL+  + +  D   FE++++    ++V+K
Sbjct: 11864 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 11899



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
             F+ KL    +  G+   L  + S  P   + W  +    L+  +  I +   +L    I 
Sbjct: 16824 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 16879

Query: 1159  KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
             KA   D G Y  V +N  G  +  CQV V D P                   PPV     
Sbjct: 16880 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 16921

Query: 1219  DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             D   K        P        I     +K   G+ V +    + +   TC   K  K +
Sbjct: 16922 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 16977

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             +  +++   ++EN                Y +       S +A+    V D PD P  T 
Sbjct: 16978 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17022

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
                D    S  ++W    +DGG  + +Y +E  ++ +K W  +        T F V DLL
Sbjct: 17023 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 17077

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
                +Y+FRV A N  G  +PS  S+     +   +P   V     D     VD
Sbjct: 17078 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 17130



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QL  PV++K L                   PP F        V  G+  +      GRP
Sbjct: 22133 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 22175

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
              P VTW K NVPL+ + RV+        +L I    ++DVG Y   + N +G+A
Sbjct: 22176 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 26/77 (33%), Positives = 44/77 (57%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V+ GQ  +    I+GRP+P +TW K  +PL+ + R++V++   +  L I   ++DD G Y
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300

Query: 232   TCLVVNGSGKASMSAEL 248
                V N  G+ + S E+
Sbjct: 23301 GITVANVVGQKTASIEI 23317



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/72 (34%), Positives = 40/72 (55%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G+  +    + GRP+P ++W+K   PL+ + RV+V E     VL I   N+DD G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382

Query: 232   TCLVVNGSGKAS 243
             T    N +G A+
Sbjct: 24383 TVTATNSAGTAT 24394



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
             P F+  + +     G   RF   I  +P+P V W+K  Q I+     + +  + D+ G  
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 31748

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              L I+ V  DDDA+YT  A N  GE +C A+L V
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 51/230 (22%), Positives = 81/230 (35%), Gaps = 35/230 (15%)

Query: 22   SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL 81
            +R++ + L   P+F    + +   +G+    E  V G     + W ++ Q I++  ++  
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723

Query: 82   DCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141
                   F L I  +   D G YTC ATN +G  Q +  LTV+                 
Sbjct: 4724 SFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------- 4766

Query: 142  DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
                              PP F  K     V      +    + G     + W K N  L
Sbjct: 4767 ------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL 4808

Query: 202  QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               A  SV + +    LE+      D G Y C + N  G A+  A L ++
Sbjct: 4809 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G   R    I GRP P+V W K +  ++ +A + V+      VL+   VN+ D G Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 23011

Query: 232   TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
             T  + N SG  + SA ++++ LD+ +                                  
Sbjct: 23012 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 23069

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
             V + +AT       VTN      K+D L+          A        P +   P   A 
Sbjct: 23070 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 23129

Query: 312   SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
               PQPP +  ++    +  +   T       S I      +Q +         R   L  
Sbjct: 23130 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 23188

Query: 364   LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
             +  +   GEE          K  + PR    P     + ++D+V +              
Sbjct: 23189 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 23229

Query: 412   AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
               P  +    S  V+  Q +K    +SG PKP + W  +G P+ +Q   I V +      
Sbjct: 23230 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 23286

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCS 499
             L + +    D G Y  T +N  GQ + S
Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTAS 23314



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E  A E    KP     ++D  V   S A+F  K  G P P  +W KD ++I +   +++
Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
               D+ G   L I      D   YTC   NS G  + + +L ++ +++ E +
Sbjct: 32901 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 32950



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            PYF+K  + +EV++        ++ G P  E+ WFKD+  +R  R ++  + +D   SL 
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQ 4451

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
            I      D  +Y C+  N +G + C+A +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARV 4480



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 53/245 (21%), Positives = 82/245 (33%), Gaps = 35/245 (14%)

Query: 24   VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
            V S+ L   P F+    ++    G   + +  + G     V W ++   I      +   
Sbjct: 7483 VGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWIS 7542

Query: 84   GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
                  +L    V   + GKYTC+  N +G ++    L+V                    
Sbjct: 7543 YSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLE------------------ 7584

Query: 144  FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
                            P     K   + V  G      C + G P+    W K    L  
Sbjct: 7585 ----------------PATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTS 7628

Query: 204  SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
              +  +S  N +  L+I  V   D GVY+  V N  GK S +A L +    +   SF R+
Sbjct: 7629 DNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSD-RTVPPSFTRK 7687

Query: 264  TKATN 268
             K TN
Sbjct: 7688 LKETN 7692



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)

Query: 1746 LEAVAEEKPHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 1804
            LE  AE +   +P  F+K I+++ V E  +A F+C++  + D  V W+K    + ES+ +
Sbjct: 8821 LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKY 8879

Query: 1805 QIDYDEDGNCS-LIISDVCGDDDAKYTCKA-VNSLGEATCTAELIVETME 1852
              ++  DG C  + I +V  DD+  Y+  A +   GEA  TAEL + T E
Sbjct: 8880 --NFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKE 8927



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 2/93 (2%)

Query: 1758 PYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            P F K +   ++V+ G ++R +CKI G P+  VVWF+++  +  S  +++ +  D    +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDSVAVI 5481

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             ++++  +D   + C+A N  G  +C+ ++IV+
Sbjct: 5482 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R      GRP P++TW +       + +V + +      L I   +++D G
Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 24091

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
              Y   + N SG  S SA ++++ LD+         K    +VRK+   ++ +   +D   
Sbjct: 24092 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 24143

Query: 290   AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
               AK KN    +R  +    AN   +  + S K+E+  +                     
Sbjct: 24144 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 24202

Query: 329   ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
                      P + P    L    +TS+S+  +        R  G  V + P G E K   
Sbjct: 24203 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 24261

Query: 376   PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
                         GL S        KA N +         +P+  +  +  P  +    + 
Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 24321

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              ++  + +K    V G P+P ++W  +G P+ +Q   + V E A S  L + +    D G
Sbjct: 24322 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 24380

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
              Y+ TA+N+ G  + + ++ V       V P  F  V  D  VI
Sbjct: 24381 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 24424



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +++K G+  R    + GRP P+VTW K  V ++    + +++  G   L +    +D  G
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027

Query: 230   VYTCLVVNGSGKASMSAELSIQ 251
             VYT    N SG A    ++ +Q
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQ 28049



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P   K ++D+    G AA+  C+I G P P++ W++  + + +SR +++  D   +   +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +++   +D+  YTC A N +GE   +++L+++
Sbjct: 30593 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 30623



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)

Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            +G A +  CK+ G P  ++ WF +D+ I+ES   ++ + E     L ++DV  +D  +Y 
Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYM 4371

Query: 1831 CKAVNSLGEATCTAELIVE 1849
            C+A N  G   C++ +IV+
Sbjct: 4372 CEAQNEAGSDHCSSIVIVK 4390



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 4/113 (3%)

Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
            S E  S +    VA ++P   P F K I +   V  S+A F   + G P   + W KDDQ
Sbjct: 5030 SNEGGSCSCSTRVALKEP---PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 5086

Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             + E  +  I +  D   +L I  V      +YTC+A N  G   C A L+V+
Sbjct: 5087 ILDEDDNVYISF-VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 48/235 (20%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F  K   V +A G+    +C V+   P  I W  + + ++      ++   +  ++++
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTV 7271

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             K    D G Y C A N AG+  CS Q+ V +                            
Sbjct: 7272 LKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE---------------------------- 7303

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRK 1276
                               PP+ I+  E  + V+  E      K+ G+  I   W K   
Sbjct: 7304 -------------------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDET 7344

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +IQES   ++   ++ + L +     E  G YT    N  GS  +  +L V + P
Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 7399



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             PT  +       + V  G  V + + ++G PPP   W   G++++ESE    E       
Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
             L I+E    DTG YT E  N  G    T  V+ + +P   T P  I +    S+T S   
Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 29855

Query: 735   ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
                 G + L    +         WL   +++ + T  F  L   + +   +     +  G
Sbjct: 29856 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 29915

Query: 791   QYEILLKNRVGECSCQVSL 809
              Y   L++ V EC   + +
Sbjct: 29916 SY---LQSEVIECRSSIRI 29931



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
            AP FI  P    + EG +  F  +V G P+P V W ++G P+T+G R+ +    + G   
Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
            LVI     +D G+YT    N  G    +  L  E  +
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F KT+   ++V G+ A   C++ G    E+ WFKD + IR S+ +++ + +     L 
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL-FSQKSLVCLE 3889

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTA 1844
            I      D  +Y C   N +G+  C A
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMA 3916



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)

Query: 1730  LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
             ++A+  +   D  Q  +  +A++   + P F        V+ G   + D    G P P V
Sbjct: 22121 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 22179

Query: 1790  VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              W KD+  ++++     +  E+ N  L I D C +D   Y  K  NS GEA  T  +IV
Sbjct: 22180 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
             K   P TP     PP+    P +       SV L     K  G   +T  +++ ++   +
Sbjct: 30315 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 30374

Query: 1281  S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
                 H K + +     +T L    E+   + ++ +N +G S  +  +  VV     DKP 
Sbjct: 30375 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 30432

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
              P      S I   S+TL W     DGG  +  Y +E   S +  WK+      +   F 
Sbjct: 30433 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 30491

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
             +  LL   EY+FRV A N  G S P     S +++LT+ GE P   K+  +V+
Sbjct: 30492 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 30543



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P F+ + ++  V+        C+V+G PKP V W+ +G  +        + E  G ++  
Sbjct: 30928 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 30987

Query: 474   LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
             ++ + T D  T Y   A+N  G +S + +L+VE  A + + P     +     + G+   
Sbjct: 30988 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 31046

Query: 533   LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
             ++    G P P ITW   GQ +       +  V         P     +D G Y   A+N
Sbjct: 31047 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 31105

Query: 588   ALG 590
               G
Sbjct: 31106 RFG 31108



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)

Query: 171   VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V +EG   ++ CKI    Q  QVTW  G   L+ S +  ++ ++G+ +L +  + + D G
Sbjct: 31578 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 31637

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
              Y C VVN  G+ S  AEL ++G+      + R T
Sbjct: 31638 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 31672



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 54/233 (23%), Positives = 82/233 (35%), Gaps = 48/233 (20%)

Query: 1100 FKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
            F +KL+   + + G    L C+V+  PP  I W  N + +K +    +S   S   + + 
Sbjct: 4301 FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
                ED G Y C A+N+AG   CS  V V ++P                           
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY-------------------------- 4394

Query: 1219 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
              T + KP                     +V     V L  +V GT P   TW K    +
Sbjct: 4395 -FTKEFKPI--------------------EVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 4433

Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +     K    ++   L IL       G Y   V N++GS      +T+ + P
Sbjct: 4434 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 4486



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)

Query: 1105  QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
             ++ H+  G  L L   +   P   + W    +   T   I ++  GS   + I  A  ED
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 17283

Query: 1165  RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
              G+Y    +N AG    S +V V D P              P+      +  +S     K
Sbjct: 17284 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 17331

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P                         G SV     V      +  W       ++  H 
Sbjct: 17332 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 17369

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
                 +E    L  +AA            EN+ G          +   DP  P G P    
Sbjct: 17370 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 17417

Query: 1342  --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
               D+  + ++L W     DGGS +  Y +E  +   + W +  T  +    V  L     
Sbjct: 17418 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 17477

Query: 1400  YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             Y+FRV+A N+ G   P     +    EK   P  E++V
Sbjct: 17478 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 17514



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L IK G + + +  V+G P P+VTW ++G  I       +   + G+ SL +     + R
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 28026

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
             G YT EA N SG+ +  +++ V+ +  K +G    +   G++ +
Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)

Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
           ++A P F  + QS  V++   V+ +  V+GIP P V ++ +G  + +     ++ ++   
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158

Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
           + L + +A   DSGTYS  A+N+ G+ + +  L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 51/244 (20%), Positives = 83/244 (34%), Gaps = 55/244 (22%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSV 1155
            AP F + L++V         L C+++   P  + W  +GK +  + ++ I   EG+  S+
Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT-ASL 4170

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
             I +    D G + C A N  G  + S  + V +                          
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204

Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
                                 PP  +  P  + V  G +V L     G+ P+T  W K  
Sbjct: 4205 ---------------------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 4243

Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVD 1329
            K++       +      S L +   +    G YT  V N  G  +   NL      T V+
Sbjct: 4244 KELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVE 4303

Query: 1330 KPDP 1333
            K +P
Sbjct: 4304 KLEP 4307



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)

Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
            + ++V E      +C + G P+ +V W KD + I  SR+F + + E+   S  I  V   
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF-ENNVASFRIQSVMKQ 5206

Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
            D  +YT K  N  G ++C A L V
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRV 5230



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
             W K  K +  + H KV     G               + +  EN  G          +  
Sbjct: 26716 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 26764

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
             +D  +PP      +DI  +S++LSW   ++DGGS +  Y +E  D  +  W +       
Sbjct: 26765 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 26823

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
              T F +  L  + +Y+FRV A N  G+ S PS+
Sbjct: 26824 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 26856



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P F + ++D+  + G++   +C++ G     V WF+D   I      Q  + E+  C+
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCT 6797

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L +S +   D   YTC A N  G   C+A L V+
Sbjct: 6798 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1816
            P F K + D+  V G   +    IEG     VVWFKD  + +RES +  I Y E+   +L
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-IATL 7550

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              S V   +  KYTC+  N  G   C A L V
Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSV 7582



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
             +  P PP   P  +D  S+++ L W   +++GG  +  Y ++        W        +
Sbjct: 15000 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 15057

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
                + V+++    +YK RV A+N  G   P  E++  TV E  E P  E++VS
Sbjct: 15058 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 15109



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P F++ +++   V G++   +CK+ G     V WF +   I     +Q  +  D  C+
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCT 5856

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L ++ +   D   YTC A N  G   C A L V+
Sbjct: 5857 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ 5890



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)

Query: 1125  PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
             PP T+ W  + K L +     +    S   ++I +    D G Y    +N  G+ + S  
Sbjct: 27299 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 27358

Query: 1184  QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
              V V D PA+      +  SR   + L  PP++   S   +  ++K+ A K         
Sbjct: 27359 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 27410

Query: 1239  QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
                                            TW     +   +    ++ SE        
Sbjct: 27411 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 27436

Query: 1299  AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
                      + +L EN++G  +       V   + PA     S  D   +S+ LSW    
Sbjct: 27437 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 27487

Query: 1357  YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             +DGGS +  Y +E      +TW      ++    V  L      +FRV A N  G S+P 
Sbjct: 27488 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 27547

Query: 1417  QESELTTVGEKPEEPKDEVEVSD 1439
                 + TV E    P  EV++SD
Sbjct: 27548 TIGPI-TVKELIITP--EVDLSD 27567



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
             SE   K+T L    E+   + ++ EN  G   A     L    +P  P G P     +D 
Sbjct: 28208 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 28265

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
               ++++L W    +DGG  +  Y IE+  +    W ++    C  T + V DL    EYK
Sbjct: 28266 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 28325

Query: 1402  FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             FRV AIN  G  +  + +      ++   P+ +++ +
Sbjct: 28326 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 28362



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F K + DL  + G        + G     V W K  + IRE    ++ +  +G   LI
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 3982

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I DV      KYTC A N  G  T   ELIV+
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4014



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%)

Query: 1742 SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 1801
            S A L   A + P   P+F++ ++D+    G    F+C+I G    +V W+KD   +++ 
Sbjct: 7103 SSAVLVIKARKLP---PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDD 7159

Query: 1802 RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
             + Q  +  +   +L I         +Y C A N LG A+ +A+LI+   E
Sbjct: 7160 ANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 55/281 (19%), Positives = 99/281 (35%), Gaps = 50/281 (17%)

Query: 1041 AKPAETLKPMGNAKPD--ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAP 1098
            AK    ++P GN K    EN  + +  ++ K       C   +    D+          P
Sbjct: 7246 AKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305

Query: 1099 AFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             F +KL+   + +  +    +C++   P   ++W  +   ++ +    +S   S+  + +
Sbjct: 7306 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 7365

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
                 ED G Y C A N AG A  S  + V +                     PP+    
Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE---------------------PPIF--- 7401

Query: 1218 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                 +KKP P    K                  G  V L  ++ GT P   +W K +++
Sbjct: 7402 -----RKKPHPIETLK------------------GADVHLECELQGTPPFHVSWYKDKRE 7438

Query: 1278 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGS 1318
            ++  +  K+ +    + + IL       G Y     N +GS
Sbjct: 7439 LRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 7479



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 718   GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
             G  P    + + VT  LG++  +SC I G P P + W R GK L + +  +++  +    
Sbjct: 30530 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 30588

Query: 778   TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             TL +   +    G Y  +  N VGE      L+LQ
Sbjct: 30589 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 1/94 (1%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P+F      +++  G +  F C + G    ++ W KD++ IR   ++++   E+   +
Sbjct: 7210 VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN-TAT 7268

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L +  V   D  +YTC A N  G+ +C+A+L V+
Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)

Query: 145   SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
             S P  E +     E P  F     L  + VK G        +TG+P+P++TW K ++ L+
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 13732

Query: 203   PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
                R+++        + I    + D G Y    VN  G+A+   E+++            
Sbjct: 13733 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 13792

Query: 253   LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
              D  N S +        D   ++TN + +    DS
Sbjct: 13793 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 13827



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
             P PP G P        S+ +SW     +GGS +  Y +E  +  +  W  ++        
Sbjct: 15599 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 15657

Query: 1385  -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
              +   FNV  LL   +Y+FR  AIN  G   PS+ S+    G+   P  P    EV D
Sbjct: 15658 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 15715



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L   V   PP  I W+     L+    + +        +  E     D G Y   
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 19767

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G+ E +  V V D P                   PPV  T  + +         P
Sbjct: 19768 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 19809

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P       II +   ++       +   K   T    C+   FR          V N E 
Sbjct: 19810 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 19852

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
             G               + +  EN+ G          V     P G      +RS   SS 
Sbjct: 19853 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 19900

Query: 1349  TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
             ++ W     DGGS +  Y ++     NK W+ +    S  ++ +DL    EY FRV A N
Sbjct: 19901 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 19959

Query: 1409  VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
               G   P   SE+T V       +D+V   D D K
Sbjct: 19960 ENGEGTP---SEITVVA------RDDVVAPDLDLK 19985



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             S +  +GQ + I   I+G P PT+ W +DG  L K T    V  + D+ TL +K+     
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 23296

Query: 789   AGQYEILLKNRVGECSCQVSLM 810
              GQY I + N VG+ +  + ++
Sbjct: 23297 GGQYGITVANVVGQKTASIEIV 23318



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             VV++     R    I GRP+P+V W K    L   A++ V+  +   +L I  V + D G
Sbjct: 25117 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 25174

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
              Y   + N SG  S +A ++++ LDS +      +RE K  +          D   ++TN
Sbjct: 25175 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 25232

Query: 278   VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
              I ++ +      A  + NC+         Q G S  +   +  +       E+ +    
Sbjct: 25233 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 25292

Query: 331   TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
             + P  P  + T   +T   A ++ E        +  G  V   +    K     +  T  
Sbjct: 25293 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 25352

Query: 384   TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
                 GL  G + V   AA         R    P      E KP  +       VK  + +
Sbjct: 25353 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 25412

Query: 432   KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
             K      G P+  V W  +G  + ++   + V        L + +A   D GTY    SN
Sbjct: 25413 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 25471

Query: 492   AQGQLSCSWTLQV 504
             + G ++   T+ V
Sbjct: 25472 SAGSITVPITIIV 25484



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F K I     + G  A F   ++G     V W KD   I E  + ++ + E+   SL 
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 4544

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +S +    D KY C+A N  G   C+A L V+
Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 40/81 (49%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + VK G        + G+P P V+W K    L+P+  + ++ +  +  LE+  VN+ D G
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 19364

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              YT    N SG  S + +L +
Sbjct: 19365 DYTITAENSSGSKSATIKLKV 19385



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)

Query: 1131  WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
             W+  GK ++ +    ++   +   ++I+ A  +D G Y   A N  G      +VTV D 
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472

Query: 1191  PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
             P                   PP     S+ + +K     TPP       I  +  +++  
Sbjct: 20473 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 20512

Query: 1251  AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
               E+  L             W    + IQ   H+  +  + G++     +   H G    
Sbjct: 20513 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 20553

Query: 1311  LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
                   G       + +VD+  P  P   P  S++  ++ T+SW     DGGS +  Y +
Sbjct: 20554 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 20608

Query: 1369  EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
             E  +  +  W        +     V  L     Y+FRV A N  G   PS+ S+   + +
Sbjct: 20609 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 20668

Query: 1427  K--PEEPKDEVEVSDDDEK 1443
                P  P     V+D  +K
Sbjct: 20669 AAYPPGPPSNPHVTDTTKK 20687



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)

Query: 12    ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
             I++T++++ P    S P+T   A  +PPR          L +K G     +  V G P P
Sbjct: 19267 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 19325

Query: 63    QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              V+W ++G  +    G +  +    R   +L + +V+ +D G YT  A N SG++  T++
Sbjct: 19326 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 19382

Query: 121   LTV 123
             L V
Sbjct: 19383 LKV 19385



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 1325  LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
             +  +D   PP     P  +D   +S++L+W     +GGS V  Y IE+       W +  
Sbjct: 30024 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 30081

Query: 1383  TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
              C +T   +++    H     EY+FRV A N  G  EP++      V E  E P  E++
Sbjct: 30082 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 30139



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
             + + PS        ++  G+D  ++  V G P P I+W+ +G+P+ Q  R   E  A   
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367

Query: 567   ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
              LHI++   +D G YT  A N+ G  + +  V V EK
Sbjct: 24368 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 24404



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QLG PV+++          +E +PS+  E P  F T      VK  +  +      GRP
Sbjct: 25380 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 25422

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             Q  V W K    L+ + RV+VS    +  L I   +++DVG Y   V N +G  S++  +
Sbjct: 25423 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 25480

Query: 249   SIQGLD 254
             +I  LD
Sbjct: 25481 TIIVLD 25486



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)

Query: 106   CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
             C  TN         ELT +  +  +    V ++   D  S P+  T P I  +   PP+ 
Sbjct: 25734 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 25789

Query: 164   ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
                +     +VVK G++ + +  I GRP P ++W K  + ++  AR  +   +   +L +
Sbjct: 25790 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 25849

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + D G Y   + N +G  S++    +
Sbjct: 25850 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)

Query: 1700  AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
             AV +  + S M   S +   KS        L++ +  +  ++  A LE  + E+      
Sbjct: 32495 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 32554

Query: 1760  FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
                T+        R + V EG +ARF C  +G P P V W +  Q +  S   Q+   + 
Sbjct: 32555 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 32613

Query: 1812  GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                +  IS V   D+  Y+    NS G+      L ++
Sbjct: 32614 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
            +++   KP+F K +  L +     A F+C++    DP +V  W  D + +  +   ++  
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +E G CSL        D    TC+A N  G    +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F K    LEV+ G    F   I G P  +V WF+  + + +     I Y ED    L 
Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELE 5951

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            + ++      +YTC   N+ G+A+CT  L V+
Sbjct: 5952 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)

Query: 1263  GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
             G  P+T  ++  ++++      KV +     + T+    Q     + +   NK G  +  
Sbjct: 13515 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573

Query: 1323  -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
                  VN+ T    PDPP       D  ++S+ L+W     DGGS ++ Y +E     + 
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 13632

Query: 1377  TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
              W         T   V  L     Y +RV+A+N  G S+PS+ +E     +  E P+  +
Sbjct: 13633 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 13692

Query: 1436  EV 1437
             +V
Sbjct: 13693 DV 13694



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)

Query: 426   KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
             K    ++    + G P P+ +W  +G   +  ++G  ++ EDA       S  + + + +
Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882

Query: 479   TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
                +G YS TA N  GQ + +  ++V       + L V ++      +       +G D 
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 15941

Query: 532   VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
                  ++G  + + T  ++G+        C  G     + D L E    +   AEN  G 
Sbjct: 15942 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 15992

Query: 592   VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                   V   ++ ++R      P+ P  P           +K+  G     TV +S  PP
Sbjct: 15993 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 16035

Query: 652   PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
                            + W   G + +     + ++   +    ++++       +  +A 
Sbjct: 16036 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 16094

Query: 699   NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
             N+AG  +  A +   +      P  I     +    G +V I   I G PFPT+ W +  
Sbjct: 16095 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 16154

Query: 757   ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
                 D K       H   L  +D  TLV+ + +    G Y I   N +G  S ++ L
Sbjct: 16155 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 16211



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)

Query: 575   PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
             P D   +  +A NA+G +S            S+ S  ++     V P     P +  GL 
Sbjct: 27920 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 27969

Query: 631   DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
                +  G  + +   V G P P V W  +G EI++  +          SL +++   +  
Sbjct: 27970 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 28026

Query: 691   GTYTCEAWNSAGEVRTQAVLTVQE 714
             G YT EA N++G  + +  + VQ+
Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQD 28050



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            ++  + P F++ ++D+E   G      C++ G    +V W++D   +R+  + Q  +  D
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VD 6227

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
               +L I         +Y+C A N LG A+ +A L
Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 47/244 (19%), Positives = 83/244 (34%), Gaps = 35/244 (14%)

Query: 26   SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
            S+   E P F+    +     G   +    V G+    V W ++   +           I
Sbjct: 6544 SVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFI 6603

Query: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
                +L + +    + GKY C+  N +G R+ +  LTV                      
Sbjct: 6604 DNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE-------------------- 6643

Query: 146  APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
                          P +   K   + V  G      C +TG P+    W K    L   +
Sbjct: 6644 --------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADS 6689

Query: 206  RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            +  ++  N +  L+I      D G+Y+  V N  GK++ +  + +        SF+R+ K
Sbjct: 6690 KHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSD-RIVPPSFIRKLK 6748

Query: 266  ATNS 269
              N+
Sbjct: 6749 DVNA 6752



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
             +++P PP     +SD   SS+ L W     DGGS +  Y IE  +     W    +    
Sbjct: 13289 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 13347

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
               ++ V  L   ++Y +RV A N  G S+PS+     T  +   EP  ++    D
Sbjct: 13348 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 13402



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)

Query: 574   LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
             +P++  T T L E A  Q    A   V+    S  S+ +  +A +  P   + +   S L
Sbjct: 19246 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 19305

Query: 633   KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
              V  G+ V +   V G P P V W  +G  ++ +E     +   Q +LC  E+F    +D
Sbjct: 19306 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 19362

Query: 690   TGTYTCEAWNSAG 702
             +G YT  A NS+G
Sbjct: 19363 SGDYTITAENSSG 19375



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 25/82 (30%), Positives = 36/82 (43%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             + KE    R    I G+P P V+W KG  PL    RVSV        L ++   + D G 
Sbjct: 19993 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 20052

Query: 231   YTCLVVNGSGKASMSAELSIQG 252
             YT  + N +G    +  + + G
Sbjct: 20053 YTITLKNVAGTKEGTISIKVVG 20074



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             LT  P+  LP     I+ G   K E  V G P P ++W ++G+P+    R  ++     T
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367

Query: 89    FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               L I   +++D GKYT  ATN +G     + + V
Sbjct: 24368 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
             NA    S    S   +    E  P +  +  +    L +  G + R    ++G P P V 
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 27991

Query: 1791  WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             WFKD   I +  + +I  D  G+ SL + D   D    YT +A N+ G A    ++ V+
Sbjct: 27992 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
             I+ G+    +  V G PEP++ W +  + +    +  L   G R T   VI      D G
Sbjct: 29059 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 29116

Query: 103   KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
             KYT    N SG + V+V + V  S     G+  VS+   ++    +S P  +    I   
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 29175

Query: 159   CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
                +  T     V+ EG+    S  +T   +      +V  +    P  P     +  +N
Sbjct: 29176 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 29235

Query: 214   GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
                +    G+ ++   G    ++     ++    E+S   +D   +  +R T+       
Sbjct: 29236 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 29295

Query: 270   -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
              D R +VT+++               + C    R  +   A NS+P     S   SC++ 
Sbjct: 29296 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 29338

Query: 328   ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
                  P +AP+  V+  T  SI+L   +   +     +G +    E+           A 
Sbjct: 29339 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 29396

Query: 377   PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
              R   F      +G +     AA   + ++G  + +    E +P                
Sbjct: 29397 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 29453

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
             ++  ++   +++    VSG P P + W  +G  +     S  + +   S+ L ++ K   
Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 29509

Query: 480   RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
              D+G Y+  A N  G+ S +  ++V         + V EV+    ++  +   I+G    
Sbjct: 29510 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 29565

Query: 533   LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
                   G PV   I          +   T +       I   +      +  L EN  G 
Sbjct: 29566 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 29619

Query: 591   --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
                   S  V V E          +P+ P+K            L+V+D ++ T+T  ++ 
Sbjct: 29620 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 29655

Query: 649   NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
               P     L++G            + GT+  + +  + P   E T T   E       +R
Sbjct: 29656 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 29710

Query: 706   TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
              Q    V EP +      +   R             ++    G+ V +   IAG P P  
Sbjct: 29711 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 29770

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              W   G  L +++    V  +  V  L +++      G+Y + LKN  G  S  + +++ 
Sbjct: 29771 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 29829

Query: 813   NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
             +               A ++    EP   +    GG    G   ++  + RPGW
Sbjct: 29830 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 29879



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
             P PP G P         + + W     DGG+ + +Y ++  +  +  W  +        T
Sbjct: 29240 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 29298

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                V  L+   +Y+FRV A+N  G SEPS+ S   +  E    P
Sbjct: 29299 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 29342



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
             V +   S  S++   ++P     +P  E    +   + + I+ GA+ +    V G P P 
Sbjct: 29420 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 29477

Query: 64    VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             +TW + G  + S  R ++D        L++  V+  D GKYT EA N SG +  TV + V
Sbjct: 29478 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)

Query: 1111  EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
             EG  +   C++ + D    + W    + L+ ++   ++ E  +  + ++     D G Y+
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 31640

Query: 1170  CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
             C   ND G+     ++ V         +  +   RR               T+KK K   
Sbjct: 31641 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 31680

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
              T      PP+      ++    GE+V     +T       TW K  ++I+  ++ K   
Sbjct: 31681 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 31740

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
              E+ +   +LTI +   +    YT++  NK G    +  LTV   P P            
Sbjct: 31741 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 31800

Query: 1335  -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
                     G     +IR S +   TL W     DG       +IEI       +      
Sbjct: 31801 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 31851

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
                + +++D LP+    +RV A N  G++      ++  +  K +E K + E     +K+
Sbjct: 31852 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 31908

Query: 1445  PEVDYRTVTI 1454
              +   R   I
Sbjct: 31909 IDKTLRMAEI 31918



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 29/217 (13%)

Query: 1651 CYILNRLDCTQCLQH------PWLMKDTKNMEAKKLSKDRMKKYMARR-----KWQKTGN 1699
            C   N+    QC  H      P+ ++  ++ +    ++ ++K  +        KW K   
Sbjct: 4747 CSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNK 4806

Query: 1700 -----AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV--AEE 1752
                 A R++ +  +   +   + + + +G+    L+        DV  A  +A    +E
Sbjct: 4807 ELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS-------NDVGTATSKATLFVKE 4859

Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
             P    +  K    L +  G +  F+C+I G P   V W+ D   I   +   I +  DG
Sbjct: 4860 PPQ---FIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDG 4915

Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +  IS    ++   Y C+A N  G A+C+ EL V+
Sbjct: 4916 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 4952



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 1756 VKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            + P F+K + + +E  EG++ + + ++ G     V W+K++  I+ + + +I + ++   
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTL 8305

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             L +     +D   YTCK  N  G A CT+ ++++
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)

Query: 388   GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
             GLG  D         IP+E Q     P  E   +  E   VK   TV+F   + G+P P 
Sbjct: 17489 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 17541

Query: 445   VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
               W  +G+ ++  E    V  D  S  L +     RD+G Y  T SNA G  + +  L V
Sbjct: 17542 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             LP      KE +  + +  ++G P P V+W +   P+ +  R  ++     T +L+++  
Sbjct: 19987 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 20045

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTVEG 125
              + D GKYT    N +G ++ T+ + V G
Sbjct: 20046 QKSDAGKYTITLKNVAGTKEGTISIKVVG 20074



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)

Query: 1717  SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
             S ++  +  P+ P      E++    E V    + A  +    +K   SK I  L  VVE
Sbjct: 32681 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 32740

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
              S  R           EV W+KD + ++E+ HFQ  Y  DG   L I+++   D  +Y C
Sbjct: 32741 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 32791

Query: 1832  K 1832
             +
Sbjct: 32792 E 32792



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L+DV+V EG K +L+C+VS     ++ W LN + +K    +    +G+   + I +    
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
            D G YK +     G+ E +C ++V+
Sbjct: 2511 DEGPYKLI----VGRVETNCNLSVE 2531



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 2/92 (2%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1816
            P F K + D   + G A      +EG+    VVW KD  + IRES + +I +  D   +L
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATL 6609

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             +      +  KY C+  N  G   C+A L V
Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%)

Query: 1748 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
            ++  ++P   P F + +  + V EG   +  C ++G     + W K  + I+ S      
Sbjct: 8336 SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS 8395

Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +   G   L + DV   D   Y CKA N  G  T  +++ ++
Sbjct: 8396 F-ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 1754  PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
             PHV+  F + + DL+V E   ARF+C++    + +V WFKD   I++ + + I   +   
Sbjct: 12372 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 12427

Query: 1814  CSLIISDVCGDDDAKYTCK 1832
               L+I+    DD+A+Y+C+
Sbjct: 12428 RILVINKCLLDDEAEYSCE 12446



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
             ++E  P +   L    +  G+   ++  V+G PVPR+TW  +G  I+   +   T   G 
Sbjct: 27957 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 28013

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
               L ++DA  +  G YT  A+NA G       V V +
Sbjct: 28014 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 28050



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            E  H++  F K I+D++V+E   A F+C++   PD  V W KDDQ ++ +   +I  ++ 
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +  L+I      D  KYT  A    G    TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F +T   +EV+ G +  F   I G P  +V WFK  + +       I   ED    L 
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISL-EDFVTELE 6892

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            + +V   +   Y+C   N  G A+CT  L V+
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)

Query: 115   RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
             RQ TV+   EG+  K     V +   G     P  ET+P    E     A +L     G 
Sbjct: 15059 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 15113

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + +  G+  R    +TGRP P   W K    L    RV +        L I    + D G
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 15172

Query: 230   VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
              Y     N  G    +A           L ++ + +  +  +        D   E+T  I
Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 15232

Query: 280   --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
                K++K+ +    +E      + +    G    +   ++ +    PP E       D  
Sbjct: 15233 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 15292

Query: 328   SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
              P T+P+     ++T S+ITL       EPR+ G   +     E++R   P         
Sbjct: 15293 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 15348

Query: 382   FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
              PT    + + D         KA N        +P+    Q D   P    +   +  + 
Sbjct: 15349 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 15408

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
             +VK  + V    +V+G+P P++ W    T + +   ++++ ++  S       L + KA 
Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468

Query: 479   TRDSGTYSCTASNAQGQL 496
               D GTY+ TASN  G +
Sbjct: 15469 REDKGTYTVTASNRLGSV 15486



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)

Query: 511   EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
             +V P+FSS     +V  GQD  ++  + G P P ITW  +G P++       T    +  
Sbjct: 23231 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 23286

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I++   +D G Y     N +GQ + S  +   +K             P  P  P+   
Sbjct: 23287 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 23333

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPP 651
              +S            ++ +S NPP
Sbjct: 23334 DVS----------AESITLSWNPP 23347



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             +  G  + + + V G P P + W+ +G  ++++   + E+  T   L I+E   +D G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382

Query: 694   TCEAWNSAG-EVRTQAVLTVQEP 715
             T  A NSAG      +V+ +++P
Sbjct: 24383 TVTATNSAGTATENLSVIVLEKP 24405



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +K G   + E  V G P P + W ++G+ +    +  +      T +LV       D G 
Sbjct: 21473 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 21531

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
             YT  ATN              G FAK +    V    G      +   V +   +    P
Sbjct: 21532 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 21578

Query: 161   P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
             P      K+   +V++ +  R +       + QVT LK    L+ +    RV    K G+
Sbjct: 21579 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 21637

Query: 216   -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
                     VL ++     D              +  C     S   S      ++  D A
Sbjct: 21638 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 21697

Query: 257   NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
              + +++  K T +D+R +V+ +    E +   +   A   +  SP            +P 
Sbjct: 21698 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 21757

Query: 316   PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
             PP   + L++ + S   A   P+    S           PE        P A GL   S 
Sbjct: 21758 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 21816

Query: 367   SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
             +          +   +     GLG   +V    KA +R +P E + D+   K  +     
Sbjct: 21817 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 21871

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
              ++   T++    + G P PEV W  +       E   +   ++ S Y  L+       D
Sbjct: 21872 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 21925

Query: 482   SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
             SG Y  T  N+ G  S    ++V       + L V EV  +  ++  D  +++G   +  
Sbjct: 21926 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 21985

Query: 535   CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
               V      R       +      + C     ++   D L E    Y   LAEN  G + 
Sbjct: 21986 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 22034

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               A      K S R      P+ P K T            +MD ++   +V +S   P  
Sbjct: 22035 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 22073

Query: 654   VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                 H+G           + +G+ + + C      E T T   +    +  V  Q    +
Sbjct: 22074 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 22129

Query: 713   QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              +P   + P  I+K             + T   G+ + +     G P P V W +D   L
Sbjct: 22130 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 22188

Query: 762   CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
              K T        E+   L +K       G Y + L N  GE
Sbjct: 22189 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 22228



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)

Query: 1228  PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
             P  PP A   P++     +   +R  E         G   I   W+  K R  I   +  
Sbjct: 28837 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 28891

Query: 1285  KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             KV   E   K+T L    E+    Y L       + +A   +   +  D P G P  +D+
Sbjct: 28892 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 28950

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
               S+++L W   +YDGGS V  Y IE   + +  +  W +          F V  L    
Sbjct: 28951 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 29010

Query: 1399  EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
              Y+FRV A N  G  S+ S+ +   T  ++   PK E++
Sbjct: 29011 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 29049



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)

Query: 656   WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
             W+ +G+ I+ES    F   G    L I +V   D G YTC       E  + A L V+E 
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210

Query: 716   HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
                   +  +    VT   GQ + +SC +  +    V W +DGK + +  G         
Sbjct: 11211 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 11265

Query: 776   VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
             +  L +       AG Y + ++N    ECS  V ++
Sbjct: 11266 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
             P  P G P   D+  S+++L W    +DGGS +  Y +E        W    T       
Sbjct: 19189 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 19248

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               +    L    +Y+FR  A      S PS+ S+  T+  +   P+ ++ V+
Sbjct: 19249 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 19300



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
             L +K G T +F   +RG P P   W  +G  I +   + ++      FS  L I      
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 17576

Query: 100   DRGKYTCEATNGSGARQVTVELTV 123
             D G+Y    +N +G++ V V LTV
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTV 17600



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 601   HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
             +EK  S   +  +PV A      P F    +   V+ G  + + V   G P P V W  +
Sbjct: 22125 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 22184

Query: 660   GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
                ++++   + E       L I++   ED G Y  +  NSAGE + T  V+ + +P   
Sbjct: 22185 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 22244

Query: 719   TQP 721
             T P
Sbjct: 22245 TGP 22247



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            + V  G     +CK+ G P+  V W+KD + +  S+  +  +  +   SL I  V   D 
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 5771

Query: 1827 AKYTCKAVNSLGEATCTA 1844
              YT +  N++G+++CTA
Sbjct: 5772 GTYTFQVQNNVGKSSCTA 5789



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 54/235 (22%), Positives = 90/235 (38%), Gaps = 42/235 (17%)

Query: 20   DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRF 79
            D S   ++ +   P F   P  +   +G+    +  + G P  +V W ++ + + +  +F
Sbjct: 6445 DASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKF 6504

Query: 80   LLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLGQPVVS 137
             +      T SL I  +   D G+Y C+ATN  GS     +V+      F K+L     S
Sbjct: 6505 KITSKHFDT-SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSD--TS 6561

Query: 138  KTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK- 196
              +GD     AVE R  + G  P                               V WLK 
Sbjct: 6562 TLIGD-----AVELRAIVEGFQP-----------------------------ISVVWLKD 6587

Query: 197  -GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             G V ++ S    +S  + +  L++      + G Y C + N +G    SA L++
Sbjct: 6588 RGEV-IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 1/82 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            ++V  G     +C + G P+    WFKD + +     ++I +    +  L I +V   D 
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 7653

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
              Y+ +  N +G+ +CTA L V
Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQV 7675



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F +    ++V+ G+   F   ++G P   V WFK    +       +   ED    L 
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELE 7833

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            + DV      +YTC   N  G+A+CT  L ++
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V+V+ G   R    + GRP P+VTW K  +      +  V   + M  L I    +DD G
Sbjct: 18616 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 18674

Query: 230   VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
              Y+  +VN +G+ ++   + +      +     S V +T          +D   +VT+ I
Sbjct: 18675 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 18734

Query: 280   SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
              ++ + D                                A        P     P  A++
Sbjct: 18735 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 18794

Query: 312   --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
               S+P PPR+ ++     +  T    P L+    K    IT      QP  R     V+ 
Sbjct: 18795 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 18854

Query: 366   ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
                        G++ K     R A   + P    G      V +A  + +P         
Sbjct: 18855 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 18899

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             PK    P+   +K  + ++    V G P P   W  +G         + V++   S  L 
Sbjct: 18900 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 18957

Query: 474   LLKARTRDSGTYSCTASNAQG 494
             +     +DSG YS TA N+ G
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 160   PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             PPK      ++ +K G+  R    + G+P P   W KG   +  S+ ++V + +   +L 
Sbjct: 18899 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 18957

Query: 220   IHGVNQDDVGVYTCLVVNGSG 240
             I  V + D G Y+    N SG
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            KP+F K +  ++         +C+++      V W KD Q +   + ++I + ED   +L
Sbjct: 3643 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATL 3701

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             I      D   Y C A N  G ++C+A + V
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)

Query: 4     VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
             VK V ++ +SK S +V P    R D  P  +   F+       ++EG       +++G P
Sbjct: 16091 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 16144

Query: 61    EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
              P +TW +       N +P+   T   + ++D     T +LVI      D G YT  A N
Sbjct: 16145 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 16200

Query: 111   GSGARQVTVELTVEG 125
               G     + L V G
Sbjct: 16201 NLGTASKEMRLNVLG 16215



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)

Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            + +KT++++EV E   A F+C++  +  P  +W K+   I  S  F+I      +  LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
             +   +D A+YT    N    AT T   I+ T    +   EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
             +EV EG+      KI+G P P + WFK      +++   + YD        D  C+L+I 
Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 16184

Query: 1820  DVCGDDDAKYTCKAVNSLGEAT 1841
                  D   YT  AVN+LG A+
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS 16206



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V+ GQ  R   ++ GRP+P +TW K    L    RV + +      L+I    + D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
              Y     N SG A  SA +++  LD       +  K TN  V KE    IS E+ LD+
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 18028



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E V E K  + P        + +  G   R +  + G P P   W K +  +  S H  +
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 18947

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              +  D +  LII DV   D   Y+  A NS G  T   +++V
Sbjct: 18948 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
             NA  + SE   S   + A  E  P    + P +  TI    V  G + + D  I G P P
Sbjct: 22517 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 22573

Query: 1788  EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
              + W K DQ +  +   +I    D   SL + D    D   Y  KA N  GE + T  + 
Sbjct: 22574 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 22632

Query: 1848  V 1848
             V
Sbjct: 22633 V 22633



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
             P PP      S +   S+TL W     DGGS +  Y IE  +  +  W  +         
Sbjct: 25983 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 26041

Query: 1391  VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             V+   L    EY++RV A N  G S PS+ S L
Sbjct: 26042 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 26074



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)

Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
            +G    F ++LQD+ V E     L+C VS   P  I   W  N   LK+  K+ I S+ G
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2319

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               +++++    ED+G Y  V                                       
Sbjct: 2320 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2339

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
              + G ++   +K KP P           I+Q   DQKV  G+ V+L  KV+  + +   
Sbjct: 2340 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2387

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
            WMK  +++Q S+ + +   +    L I    +E  G Y+  +     S   +V++  VD 
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2447

Query: 1331 PDP 1333
              P
Sbjct: 2448 ITP 2450



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)

Query: 1760  FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
             F K I+D+ + E    GS+A F+C +   P   +  W KD  +IRES +H  I   +D  
Sbjct: 11117 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174

Query: 1814  CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
               +I  DV   D  +YTC       E T TA+L+VE +
Sbjct: 11175 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)

Query: 117   VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
             +  + TV G    Q  +  V++K      S P+  T P    +          PKF    
Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 23634

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
               +VV  G+  R    + G+P P + WL+G+  ++ SAR  +   +   +L +    + D
Sbjct: 23635 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 23692

Query: 228   VGVYTCLVVNGSGKASMSAELSI 250
              G Y     N +G  S    + +
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKV 23715



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
            +KS  K +++ K + + +N +  H G   +      + T+ A          F++ ++D+
Sbjct: 3008 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3067

Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
             V E K+ + +C+VS +P  T+ W  + + L+ T  I + +E  +  + I      D G 
Sbjct: 3068 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3126

Query: 1168 YKCVAKNDAGQAE 1180
            Y  VA  +   A+
Sbjct: 3127 YTVVAGGNVSTAK 3139



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             +K G   R S  I G P P+VTW K +      AR+ V+       LEI     +D G+Y
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 17287

Query: 232   TCLVVNGSGKASMSAELSI 250
             +  V N +G  ++S ++ +
Sbjct: 17288 SLTVENPAGSKTVSVKVLV 17306



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 21/72 (29%), Positives = 34/72 (47%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++++ G   R    + GRP P++TW K NV L+    + +   +    L    VN+ D G
Sbjct: 19703 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 19762

Query: 230   VYTCLVVNGSGK 241
              Y   + N  GK
Sbjct: 19763 KYILTLENSCGK 19774



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + + + V G P P V W      +++++  +FE   T   L I E    D+G Y   
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139

Query: 697   AWNSAGEVRTQAVLTVQ 713
             A N  GEV    V+T+Q
Sbjct: 21140 ARNIVGEVGD--VITIQ 21154



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
             KD  V+  G+ F +   + G P+P I W+   Q +   AR   ++      L ++DA+  
Sbjct: 22550 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 22609

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
             D G Y   A+N  G+ S    VTV+ K   R         P  P  P+ + G++  K   
Sbjct: 22610 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 22656

Query: 634   -----VMDGSQVTMTVQVSGNPPPEVIW 656
                  + DG    +   V       ++W
Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVW 22684



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 1753  KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
             +P VKP FS       V  G   + +  I G P P + W KD   ++++    +  D   
Sbjct: 23229 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 23283

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
               +L I +   DD  +Y     N +G+ T + E++
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 23318



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 736   QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
             + + I     G P  TV+W +DG+ L K+T    V  ++ V +L +K+      G YE+ 
Sbjct: 25410 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 25468

Query: 796   LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
             + N  G  +  +++++ +      P   +  SC+ +
Sbjct: 25469 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 25504



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
             F + L+D  V EG   +L+C+VS +  A + W  NG + LK+ K+ I++ +G +  + I 
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 12344

Query: 1159  KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
                PED   Y C    DA   + SC + V
Sbjct: 12345 DCTPEDIKTYTC----DAKDFKTSCNLNV 12369



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             L E   F     N+ + E  T K    V   P  +V W++  + I   GR+ +    R  
Sbjct: 12459 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 12517

Query: 89    FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
               LVI   H ED G Y C   +     +V V                             
Sbjct: 12518 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 12548

Query: 149   VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
                      E   +F +K   + + EG+   F C I+    P V W + +  L+   +  
Sbjct: 12549 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 12598

Query: 209   VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             V      +VL +      D+G Y  +V    G A  +A L++
Sbjct: 12599 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 12636



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
             G+   +   V G P+P+I W  N   I+      +             EL I  A+ ED 
Sbjct: 15413 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 15472

Query: 579   GTYTCLAENALGQVSCSAWVTVHEKKS 605
             GTYT  A N LG V  +  V V+++ S
Sbjct: 15473 GTYTVTASNRLGSVFRNVHVEVYDRPS 15499



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/93 (27%), Positives = 39/93 (41%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P+  + ++ +  L V  G+ V     + G P P   W  +G+EI+  E +  E       
Sbjct: 17508 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 17567

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
             L I+     DTG Y     N+AG       LTV
Sbjct: 17568 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)

Query: 437   VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
             V G P P+V W   G     ++G +++ +     +L +  +   DSG YS T  N  G+ 
Sbjct: 18630 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 18687

Query: 497   SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             +    ++V         L V +V  +   V       +G   V    V      R TW  
Sbjct: 18688 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 18745

Query: 550   NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
                    +  T E      H+ + +P +   +   A N  G       V     K    S
Sbjct: 18746 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 18793

Query: 610   EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
             + L     S+P  P         + ++ +++T         PP    L +G    +    
Sbjct: 18794 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 18835

Query: 667   ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
                E+     R T++S+ ++++    TG        +   A N+ G    +    V E  
Sbjct: 18836 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 18894

Query: 717   DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
             +   P  I  P  +T   G+ + I   + G P PT  W + G+     + H  V + +  
Sbjct: 18895 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 18953

Query: 777   FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
               L++K V    +G Y +  +N  G  + ++ +++ ++     P
Sbjct: 18954 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 18997



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T   G +V +   + G P PTV W +DG  L K     ++    ++ TL L  V    +
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 19363

Query: 790   GQYEILLKNRVGECSCQVSL 809
             G Y I  +N  G  S  + L
Sbjct: 19364 GDYTITAENSSGSKSATIKL 19383



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             VV+ G   R      GRP P   W K +  L  S R  +   +    L +   N++D G 
Sbjct: 28368 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 28425

Query: 231   YTCLVVNGSGKASMSAELSI 250
             YT  V N SG  S++  + +
Sbjct: 28426 YTLTVENNSGSKSITFTVKV 28445



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
             +  LA+NA G +S  +  T      + + EY    AP K      L G  DL  +  GS 
Sbjct: 29014 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 29064

Query: 640   VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             + +   V G P P++IW     E+   E    +  G + +  I+     D+G YT    N
Sbjct: 29065 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 29124

Query: 700   SAGEVRTQAVLTVQEPHDGTQP 721
             ++G   T+AV  + +  D   P
Sbjct: 29125 ASG---TKAVSVMVKVLDSPGP 29143



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             T  D ++ P  E    + G+           V ++ G        + G+P+P++ W KG+
Sbjct: 29036 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 29085

Query: 199   VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
               L    +VS+          I   ++ D G YT  V N SG  ++S  + +  LDS
Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 29140



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
            +N+ + E  TA FE  V  +  P + W +NG  I    +F +   ++G    L+I     
Sbjct: 2889 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2945

Query: 99   EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
            ED  +YT    N   +  +TV                      E+TV  EG   K L   
Sbjct: 2946 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 3005

Query: 135  VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
            V  K+                      GD     F A    +  +++ E    +F   + 
Sbjct: 3006 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3065

Query: 169  RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             + V E +   F C+++  P   V W+K +  LQ + R+ + ++  +  L I      D 
Sbjct: 3066 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124

Query: 229  GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            G YT +    +G    +A+L ++G D   RS  +E +
Sbjct: 3125 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3157



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V + Q +   CE++   + +V W  +G  V  + G I          L +  A   D+GT
Sbjct: 11224 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 11281

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
             Y+ T  NA   L CS  ++V    V  +       ++D  V      +  C +     P 
Sbjct: 11282 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 11335

Query: 545   ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             I W      +  +P        +     L I++A+PED   Y    E         A +T
Sbjct: 11336 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 11391

Query: 600   VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
             + E    R+ E L P+               D+ + +    +   ++S    P   W   
Sbjct: 11392 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 11432

Query: 660   GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
             G  ++ S     +  G +  L + +V  +  G    +A N+     T A+LTV+E     
Sbjct: 11433 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 11484

Query: 720   QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
             +  F    + VT    +     C +  +    V W + G  + K +  F+++ +     L
Sbjct: 11485 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 11541

Query: 780   VLKKVQPWHAGQY 792
             V+   Q    G Y
Sbjct: 11542 VINDSQFDDEGVY 11554



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)

Query: 1760  FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
             F+K + ++EV E    +  C++   P  EV+W+K D+ I E+  ++I   E     L+I 
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 12522

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
             +   +D   Y C+  +S  +      EL  E + + +     EGE+ E
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)

Query: 8     ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
             A+  ISK S S  P  + +    E P   + P+    + +  G T + E  V G P P +
Sbjct: 23600 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 23657

Query: 65    TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              W R  + I    R    C I+ T     L++      D G+Y   A+N +G++   V +
Sbjct: 23658 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 23713

Query: 122   TV 123
              V
Sbjct: 23714 KV 23715



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++VK G     +    GRP P V W K +  L+  A V  ++      L I   N++D G
Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 26253

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
              YT  + N    AS++  L ++ LD+        T  T  DV KE
Sbjct: 26254 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 26292



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +K  ++++ +  V G P P V WF +G  + ++  ++E+ +  GS  L +  A     G 
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 28028

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
             Y+  A NA G       ++V+      V P
Sbjct: 28029 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 28058



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
             + P       D+ + EG      C   G P PEV W    + I  +E   F I+ + D  
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 33385

Query: 1814  CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +LII DV   D   YT    N  G  + T  + + ++
Sbjct: 33386 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 24/96 (25%), Positives = 43/96 (44%)

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
             +C P    +   ++V EG+           P P V+W K    ++ S R+++   +    
Sbjct: 14384 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 14443

Query: 218   LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
             LE+    + D G+YT  + N  G A+ S  + + GL
Sbjct: 14444 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 514   PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
             P+      D  VIEG+   +    R  PVP ++W  +G+ ++ + R T +     A L +
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 14446

Query: 571   QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
               ++  D G YT   EN LG  + S  V V
Sbjct: 14447 PKSVRADAGIYTITLENKLGSATASINVKV 14476



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)

Query: 395   VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
             VSK +    P + QR    P  + K +  EV+E   V    ++ G+P P + WF    P 
Sbjct: 16099 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 16155

Query: 455   RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
             ++ +    V  D   + L     C L   ++R  D+G Y+ TA N  G  S    L V  
Sbjct: 16156 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 16215

Query: 507   LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
                  V P  F SV  D   +       +G   +    +      R TW+ ++ +P    
Sbjct: 16216 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 16271

Query: 558   RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
                C   + +L     L      +  +A+N  G         +  +  + ++ + +P AP
Sbjct: 16272 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 16320

Query: 618   SKPT 621
              KPT
Sbjct: 16321 DKPT 16324



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)

Query: 1762  KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
             K I  L V  G+  RF   I G P P   W  D   I+   H+ ++ D   +  L I + 
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 17573

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIV 1848
                D  +Y     N+ G  T    L V
Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTV 17600



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 23/80 (28%), Positives = 36/80 (45%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G++ ++   I G P P V W +DGK L +     E+       TLV+K       
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776

Query: 790   GQYEILLKNRVGECSCQVSL 809
             GQY + L N  G  S  +++
Sbjct: 24777 GQYILKLSNVGGTKSIPITV 24796



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 26/85 (30%), Positives = 34/85 (40%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L+L   V   P   IIWT   K L   + + L   G   +  I+     D G
Sbjct: 29057 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 29116

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y    KN +G    S  V V D+P
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDSP 29141



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F K + D  V  GS    +    G P   V W KD+  I +S    I   E      I+ 
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
                +D A+Y+C   N  G+  C  E +V  +E
Sbjct: 6989 STI-EDYAQYSCLIENEAGQDIC--EALVSVLE 7018



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)

Query: 604   KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
             K SR +E +  V   + P   + ++ L+ L V  G+++ +   V+G P P++ W      
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730

Query: 663   IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
             +++ +    E    + ++ I +    DTGTY  EA N  G  R  AV+ V
Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 13778



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)

Query: 1762  KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
             K +  L V  G+       + G P+P++ W K D  +++ +   I+ +     ++ I D 
Sbjct: 13695 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 13753

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIV 1848
                D   Y  +AVN  G AT   E+ V
Sbjct: 13754 KRSDTGTYIIEAVNVCGRATAVVEVNV 13780



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
             P PP      + I  ++  L W     DGGS + +Y +E  D   K W+ +  T + T  
Sbjct: 14084 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 14142

Query: 1390  NVQDLLPDHEYKFRVRAINVYGTSE 1414
              V  L     Y FRV A N  G S+
Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSD 14167



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P  IL P  + IK G   + E  V G P P   W +    + +     +      +  L+
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 18957

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I  V  +D G Y+  A N SG     +++ V
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
             ++  +A N +G +S    L V  +A  + + P+F  +     V+ G+D  +     G P 
Sbjct: 22118 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 22176

Query: 543   PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             P +TW  +  P+ Q  R   E+    + L I+DA  ED G Y     N+ G+   +  V 
Sbjct: 22177 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 22236

Query: 600   VHEKKSSRKSEYLLPVAPSKPTAPI 624
             V +K             P  PT P+
Sbjct: 22237 VLDK-------------PGPPTGPV 22248



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 20/81 (24%), Positives = 39/81 (48%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV  G+  +    I G+P P + W+KG+  L  +AR+ +   +    L +    + D G
Sbjct: 22553 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 22612

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y     N +G+ S++  + +
Sbjct: 22613 NYILKAKNVAGERSVTVNVKV 22633



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             ++ G   K E  + G P+P +TW ++G P+    R  +   +  T +L I   H++D G+
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 23299

Query: 104   YTCEATNGSGARQVTVEL 121
             Y     N  G +  ++E+
Sbjct: 23300 YGITVANVVGQKTASIEI 23317



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             ++P          +  G   + +  + G P P + W KD + ++++    ++ +   +  
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 24368

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   DD  KYT  A NS G AT    +IV
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/74 (31%), Positives = 33/74 (44%)

Query: 639   QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
             Q+ + V   G P   V W  +G  ++E+   +     T  SL I+E   ED GTY     
Sbjct: 25411 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 25470

Query: 699   NSAGEVRTQAVLTV 712
             NSAG +     + V
Sbjct: 25471 NSAGSITVPITIIV 25484



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 711   TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
             +V EP + T P  +      PR          +    G+ + I+  IAG P P + W +D
Sbjct: 25767 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 25826

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             G  + ++    E++  ++   L +K       GQY + LKN  G  S  V+
Sbjct: 25827 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 25876



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 1760  FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
             F+K + D  V EG+ A  +C++    + +V WFK+   I +S+ ++I  D      L+I 
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 12344

Query: 1820  DVCGDDDAKYTCKA 1833
             D   +D   YTC A
Sbjct: 12345 DCTPEDIKTYTCDA 12358



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + ++ G T +   RV+G PEP +TW + G+ +    R  L   +     L I      D 
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 17976

Query: 102   GKYTCEATNGSGARQ 116
             GKY   A N SG  Q
Sbjct: 17977 GKYIISAKNSSGHAQ 17991



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V+  QT++    V G P+P++ W  EG  + R E  +++ +D     L + +A   D G 
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 17978

Query: 485   YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
             Y  +A N+ G    S  + V       + L V  V     ++  +  +  G   +    V
Sbjct: 17979 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 18038

Query: 538   RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
                           +P Q   S   + V +  I+ + L  +   +   AEN +G      
Sbjct: 18039 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 18082

Query: 597   WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
               T+  K        +L + P  +P  P       +L + D  +  + ++       G  
Sbjct: 18083 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 18130

Query: 651   PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
             P   +  H    ++ S+D+    +G+  +    +          +  +  N  GE   V+
Sbjct: 18131 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 18188

Query: 706   TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
             T+ V+  +   D  +P    K   V T   G ++ +   + G PFP V W +D  A    
Sbjct: 18189 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 18245

Query: 764   DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              +   ++    D     L K +    G+Y +   N  G
Sbjct: 18246 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 18283



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             VK    V     V G P P V+W  +GT ++  EG I++        L L     +DSG 
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 19365

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y+ TA N+ G  S +  L+V
Sbjct: 19366 YTITAENSSGSKSATIKLKV 19385



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)

Query: 490   SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             S++ G ++    +++ R+++    P F   +    V  G+ F L+  V G P+P I WL 
Sbjct: 23608 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 23661

Query: 550   NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
               + I+ + + CE       A L ++DA+  D G Y   A N  G  S    V V ++  
Sbjct: 23662 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 23718

Query: 606   SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
                        P  P  P+ + G++  K
Sbjct: 23719 -----------PGPPEGPVQVTGVTSEK 23735



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 46/201 (22%), Positives = 72/201 (35%), Gaps = 29/201 (14%)

Query: 1691 RRKWQKTGNAVRAIGRLS-----SMAMISGLSGRKSSTGS----PTSPLNAEKLESEEDV 1741
            R +W K G  ++   R S       A++      K+ +G      ++   ++  +S+  +
Sbjct: 8376 RIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 8435

Query: 1742 SQAFLEAVAEEKPHV--KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
                  A A +K  V  + +F    + + VVE + A F  K+ G P P V W K      
Sbjct: 8436 KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 8495

Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE---- 1855
                    + +     L I D    D   Y C A N  GE      L V+  ++ E    
Sbjct: 8496 NQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEG 8555

Query: 1856 --------------GEGEEEE 1862
                          G GEEEE
Sbjct: 8556 DLRAMLKKTPILKKGAGEEEE 8576



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 21/180 (11%)

Query: 7    VASSHISKTSLSVDPSRVDSMPLTEAPA------FILPPRNLCIKEGATAKFEGRVRGYP 60
            VA S  +K+ +++      + P T+  A      F+  P+++ + E  TA F  +V G P
Sbjct: 8423 VAGSDTTKSKVTIKDKPAVA-PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481

Query: 61   EPQVTWHR-NGQPITSGGR-FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
             P V W +   + +  GGR F+   G      L I    + D G Y C A N  G  +  
Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEA--KLEIRDTTKTDSGLYRCVAFNEHGEIESN 8539

Query: 119  VELTV---------EGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG 168
            V L V         EG     L + P++ K  G+      +E   ++  +   K+A   G
Sbjct: 8540 VNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYG 8599



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)

Query: 20    DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
             DP+ V    L     E P  IL     R   IK G T +    ++G P P+VTW +  + 
Sbjct: 17199 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 17258

Query: 73    ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               +  R  +D    G+   + +A H ED G Y+    N +G++ V+V++ V
Sbjct: 17259 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 17306



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
             VK   T++    V G P PEVAW    + T + R    +++   A S    L KA+  D 
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 18271

Query: 483   GTYSCTASNAQGQLSCSWTLQV 504
             G Y  TA+N  G      T+ V
Sbjct: 18272 GKYVVTATNTAGSFVAYATVNV 18293



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)

Query: 598   VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
             V V+EK  S      +P VA      P      S   V  G  + + V +SG P P + W
Sbjct: 23204 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 23263

Query: 657   LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
               +G  ++++   +        +L I+E   +D G Y     N  G+   +  ++T+ +P
Sbjct: 23264 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 23323



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
             KD  V+  G+ FVL+  +RG P+P + W  +G+ ++   AR   ++ + +  L ++D + 
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y     N  G  S    V V ++             P  P  P+ + G++
Sbjct: 24774 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 24815



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
             Q+  V+   +++      G P P   W     P        +++       L +      
Sbjct: 28365 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 28421

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y+ T  N  G  S ++T++V         +   +V    ++++ D  +++G   + 
Sbjct: 28422 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 28481

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                V      R +W       Q     C   + +++              LAE       
Sbjct: 28482 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 28521

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              SA   V+E       E   P+  ++  AP        L V+D S+ +  +         
Sbjct: 28522 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 28565

Query: 654   VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
               WL   H+G            Q+  DF  E   T Q +  ++ +  +    +  +A N 
Sbjct: 28566 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 28623

Query: 701   AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
             AG    +   +   ++EP  + T        + +T   G    I   I+G P P V W  
Sbjct: 28624 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 28683

Query: 757   DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             +   L K+T    +   +D  TL +K      +G+Y + L+N  G  +  V++++     
Sbjct: 28684 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 28742

Query: 817   RAL-PRGREPASCED-LCGGGVGADGGGSD 844
                 P      S E  +   G   DGGG++
Sbjct: 28743 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 71/346 (20%), Positives = 136/346 (39%), Gaps = 57/346 (16%)

Query: 869   VRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRAN 928
             ++ + K++V  +    E     +VE    +   G+K   K L E   K  P E++  ++ 
Sbjct: 10900 LKAIPKKKVPEKPQVPE-----KVELTPLKVPGGEKKVRKLLPER--KPEPKEEVVLKSV 10952

Query: 929   LQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTSKTPVPEKVPPP 974
             L++   + +PK   ++  KV  P           ++V+  +V  ++   K P P KVP  
Sbjct: 10953 LRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--RKIPEPTKVPEI 11010

Query: 975   KPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAET 1034
             KPA P           LPA       E   A+      P    +P+    PV    P   
Sbjct: 11011 KPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIAAPV--TVPVVG 11054

Query: 1035  LKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQ 1094
              K    A   E  KP G   P + +   +   ++ + +       G     +     + +
Sbjct: 11055 KKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLK 11111

Query: 1095  GTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKTLKTT---KFII 1145
                  F ++++D+ + E    G   + +C VS   P+T I  W  +G  ++ +   +FI 
Sbjct: 11112 AVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSNIRESPKHRFIA 11168

Query: 1146  LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
               ++  L  + ++ +   D G Y CV +    +   + ++ V++ P
Sbjct: 11169 DGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 11211



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 1737  SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
             S +D SQ  +EA+   +E K  V    PYF+  ++D   VE       C+I    D  V 
Sbjct: 11991 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 12049

Query: 1791  WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
             WFKD + I+ S++  I  D      LI+      D  +YTC
Sbjct: 12050 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 12089



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)

Query: 21    PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
             PSR    + ++   EAP   L  +    L +K G   +    V G PEP++TW +    +
Sbjct: 13672 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 13731

Query: 74    TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                 R  ++  +    ++ I      D G Y  EA N  G     VE+ V
Sbjct: 13732 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V E + +        +P P V+W  +G  V+  +  + +  D  S +L + K+   D+G 
Sbjct: 14398 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 14456

Query: 485   YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
             Y+ T  N  G  + S  ++V       + +   ++  S   +  +    +G   +L   +
Sbjct: 14457 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 14516

Query: 538   RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
                   R T++    P+    +     V     +D +P     +   A N +G       
Sbjct: 14517 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 14560

Query: 598   VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                         E   PV    P  P       D++V + +   MT+  +  PP     L
Sbjct: 14561 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 14604

Query: 658   HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
             ++G             +G +    C + + P    TYT +      E    VR +    +
Sbjct: 14605 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 14662

Query: 713   QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
              EP   T P     P          S+    G  + +  +I+G P+PT+ W++D
Sbjct: 14663 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 14716



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L I+ G      GR  G P+P+V+W ++   +    R  +      T +L        D 
Sbjct: 16828 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 16886

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             GKY     N +G+R+   ++ V      + G PV   +    F     +     W     
Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 16938

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
                +K+   ++++ ++G+            V     +   + + +VS   +    +  IH
Sbjct: 16939 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987

Query: 222   GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
               N    G+   LV +     SM A+   +  D+ ++  V E    ++        D  K
Sbjct: 16988 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 17040

Query: 274   EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
              +TN I ++ +  S   A  +K+                C    R  +        P PP
Sbjct: 17041 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 17100

Query: 318   RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
              +   +K    K SP   P+       S  +T Q  R     +  G  V     G+E  R
Sbjct: 17101 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 17160

Query: 374   PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
              A   P + P T+    G +D    K     +   G+ D A        K   +P     
Sbjct: 17161 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 17220

Query: 421   -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                  + Q +K   T++    + G+P P+V W  E       +  I+V    GS  L + 
Sbjct: 17221 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 17277

Query: 476   KARTRDSGTYSCTASNAQGQLSCS 499
              A   D G YS T  N  G  + S
Sbjct: 17278 NAAHEDGGIYSLTVENPAGSKTVS 17301



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 23/81 (28%), Positives = 34/81 (41%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VVK G   RF   I G P P   W      ++     +V   N   VL I    + D G
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 17579

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y   V N +G  +++  L++
Sbjct: 17580 EYQITVSNAAGSKTVAVHLTV 17600



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             +++ A + +     +  P  V      EAP   L     + + ++ G +A+     +G P
Sbjct: 23993 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 24052

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P++TW R     T   +  ++ G+  T  L I      D GKY  +  N SG++   V 
Sbjct: 24053 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 24109

Query: 121   LTV 123
             + V
Sbjct: 24110 VKV 24112



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L L   VS  PP  I W+  G  L +   I  ++  SL  + ++K    D G
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 29513

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y   A+N +G+   +  V V D P
Sbjct: 29514 KYTIEAENQSGKKSATVLVKVYDTP 29538



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
            P F    +SV    G +      I+G P P V W RDG+ +   T    ++  ++    L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
             +  V   ++G+Y +   N  G+ +    L+++  +A        P   + L    +   
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116

Query: 840  GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
             G   R      G P     +    DG +++  L  ++            E         
Sbjct: 117  QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 894  QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
             ++  + +G+  ST  L     +E+PA++     +   Q+     +  E+K+ +    D 
Sbjct: 175  SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231

Query: 954  RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
            RS+    +   G +   +P K PP  P  P  RS     +  K +L  +   S       
Sbjct: 232  RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287

Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
                S  P+ + +   P  PV +  PA
Sbjct: 288  ---HSPSPVRHVRAPTP-SPVRSVSPA 310



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E V  + P  KP       D+ V+EG            P P V W KD + ++ S    +
Sbjct: 14376 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 14435

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               D   +  L +      D   YT    N LG AT +  + V
Sbjct: 14436 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)

Query: 518   SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
             SV     ++ G+   +   V G PVP   W      +   R   +     +EL I+DAL 
Sbjct: 15109 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 15168

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
             +DHG Y   A N+ G    +A V V +         +L + P      + L   SD +  
Sbjct: 15169 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 15223

Query: 636   DGSQVT 641
              GS++T
Sbjct: 15224 GGSEIT 15229



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
             G  + I   I G P P   W  DGKA    KD  H        E  +N  V  +++ + +
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 15882

Query: 786   PWHAGQYEILLKNRVGE--CSCQVSLM 810
               H G+Y I  KN+ G+   +C+V +M
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVM 15909



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)

Query: 668   DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             D HFE  G    H    + +     G ++ E   S G +  +    V  P     P +  
Sbjct: 22495 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 22551

Query: 726   KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
                ++    G+S  +   I G P PT+ W++  + L  +T   E+   +   +L +K   
Sbjct: 22552 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 22607

Query: 786   PWHAGQYEILLKNRVGECSCQVSL 809
                +G Y +  KN  GE S  V++
Sbjct: 22608 RVDSGNYILKAKNVAGERSVTVNV 22631



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            ++V +G  A    K  G  +    WFKD Q +     ++I   +  +   IIS     D 
Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE-KKDS 4646

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
             +YT +  N +G ++C A + V
Sbjct: 4647 GEYTFEVQNDVGRSSCKARINV 4668



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 1/81 (1%)

Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
            + +  S   F   ++G P  ++ WFKDD  +       I   E     L +  V      
Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASKTG 5398

Query: 1828 KYTCKAVNSLGEATCTAELIV 1848
            +YTC   N +G  +CT  L+V
Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLV 5419



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + V  G  + +  +V G P P++ W   G  +   +     Q   +  L I+E    D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977

Query: 692   TYTCEAWNSAGEVRTQAVLTV 712
              Y   A NS+G  +  A++ V
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV 17998



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             SV A  G+ V +     G P PTV W +D K L  D   + +   +    L + +V    
Sbjct: 27280 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 27338

Query: 789   AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
              G+Y + ++N VGE           SS  ++     PA+C+ L
Sbjct: 27339 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 27372



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L+   +G P P I+WL +G P+   ++ R +       L I++A  E  G YT +
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 27637

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
              +NA+ +++    V             L P  PSKP  PI
Sbjct: 27638 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 27664



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            G E+  T   + PAP   P    PP ++   ++  V  GESV L   ++G    T TW +
Sbjct: 921  GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 978

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               QI+ S   ++      ++L I  A  E  G +T    N+ G+      L V
Sbjct: 979  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 614   PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
             PV  ++P  P    + +     +++M G  + +   V+G P P  +W     E+ + +  
Sbjct: 15092 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 15150

Query: 670   HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
               +  GT+  L I++   +D G Y   A NS G
Sbjct: 15151 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
             L +K G T + E  VRG P P+V W   ++   +T   R  +D     + FSL       
Sbjct: 18211 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 18268

Query: 99    EDRGKYTCEATNGSGA 114
              D GKY   ATN +G+
Sbjct: 18269 SDGGKYVVTATNTAGS 18284



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)

Query: 403   IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
             IP EG+ D+   K      +  ++   T++    V G P P++ W      +R + G ++
Sbjct: 19689 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 19741

Query: 463   VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
             +       +L        D+G Y  T  N+ G+   +  ++V         + V E++  
Sbjct: 19742 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 19801

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
              + V  +  +I+G   ++   V+     R +W         +  T E       + +   
Sbjct: 19802 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 19852

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
                  +   AEN  G         + +   +R +     V  S+   P+      DLKV 
Sbjct: 19853 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 19893

Query: 636   DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
               S+ + ++   G   P       G+ I     DF  E+   Q    SL +Q    + T 
Sbjct: 19894 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 19947

Query: 692   ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
                 T+   A N  GE  T + +TV    D   P    K        A    +  +   I
Sbjct: 19948 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 20006

Query: 745   AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
              G P P+V W +    L  DT    V  +    TL++   Q   AG+Y I LKN  G   
Sbjct: 20007 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065

Query: 805   CQVSL 809
               +S+
Sbjct: 20066 GTISI 20070



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             PAF L      +  G   K +    G P P VTWH++  P+    R   +        L 
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 22206

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
             I     ED G Y  + TN +G    T+ + V        G   + +   D  +       
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 22261

Query: 153   PSIWGECPPKF 163
                WG  PPK+
Sbjct: 22262 ---WG--PPKY 22267



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD  VV  G   R +  + G P P + W + D+ I ES   +I  + D    LI+ D   
Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 23690

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y  +A N  G
Sbjct: 23691 IDGGQYILRASNVAG 23705



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 22/83 (26%), Positives = 37/83 (44%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +  K G        I+GRP P+VTW    + L+ + RVS++       L +    + D G
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 28716

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y   + N +G  + S  + + G
Sbjct: 28717 RYFLTLENTAGVKTFSVTVVVIG 28739



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)

Query: 541   PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             PV    W+ +N +PI+  +   E GV        +P+        A NA+G         
Sbjct: 14325 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 14368

Query: 600   VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
                 + S  SE ++   P  KPT  +      D+ V++G ++++ V     P P V W  
Sbjct: 14369 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422

Query: 659   NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
             +G E++ S+    +       L + +    D G YT    N  G       V  +  P  
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 14480

Query: 718   GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
                P    K   +T S       SC +  +P       P +H++ + +   + T +  V+
Sbjct: 14481 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 14530

Query: 772   QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
               E+  +  +K + P     + +   N+VG
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 14560



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 45/198 (22%)

Query: 47    GATAKFEGRVRGYPEPQVT-WHRNGQPITSGG--RFLLDCGIRGTFSLVIHAVHEEDRGK 103
             G++A FE  V   P   +T W ++G  I      RF+ D   R    L I  V   D G+
Sbjct: 11133 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDR---KLHIIDVQLSDAGE 11187

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
             YTC    G+  +  T +L VE                                 E P +F
Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVE---------------------------------ELPVRF 11214

Query: 164   ATKLGR-VVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIH 221
                L   V V +GQ    SC++    +  V W K G + ++   R+       M+ L I+
Sbjct: 11215 VKTLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 11272

Query: 222   GVNQDDVGVYTCLVVNGS 239
               +  D G YT  V N +
Sbjct: 11273 DADDTDAGTYTVTVENAN 11290



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 620   PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
             PT  + L    D +KV  G  V +   V+G P P++ W  N   I++  D          
Sbjct: 15395 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 15454

Query: 673   QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
             +   +  L I +   ED GTYT  A N  G V
Sbjct: 15455 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 15486



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/73 (27%), Positives = 33/73 (45%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V++K G+  R    ++GRP P + W K    L+ +A++ +   +    L      + D G
Sbjct: 21471 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 21530

Query: 230   VYTCLVVNGSGKA 242
              YT    N  G A
Sbjct: 21531 AYTLTATNPGGFA 21543



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
             +AP   L P+    + +  G T   E  +RG P P V W ++G+ +  +  R  +   I+
Sbjct: 24703 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 24762

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              T +LV+      D G+Y  + +N  G + + + + V
Sbjct: 24763 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 24798



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 617   PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
             PS+ T PI ++        + D+K  D      G  + +   ++G P P + W  +G EI
Sbjct: 25771 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 25830

Query: 664   QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             +E              L +++    DTG Y     N AG
Sbjct: 25831 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 25869



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/83 (24%), Positives = 38/83 (45%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             +  G+ L ++  V   P   + W  +G  ++    + ++      S+ +  A  + RG+Y
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28029

Query: 1169  KCVAKNDAGQAECSCQVTVDDAP 1191
                AKN +G A+   +V V D P
Sbjct: 28030 TVEAKNASGSAKAEIKVKVQDTP 28052



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
             ++++ G   R    + G P P  VW K++  + + R   +  D  G  S LII D    D
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 15170

Query: 1826  DAKYTCKAVNSLGEATCTAELIV 1848
               +Y   A NS G     A + V
Sbjct: 15171 HGRYVITATNSCGSKFAAARVEV 15193



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T  +GQ++ I   + G P P + W ++GK L ++    +++Q+     L +K+      
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 17976

Query: 790   GQYEILLKNRVG 801
             G+Y I  KN  G
Sbjct: 17977 GKYIISAKNSSG 17988



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L  +V G P+P ++W  +G   +P +  +   +  +  L +     +D G YT  
Sbjct: 19310 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369

Query: 585   AENALGQVSCSAWVTVHEK 603
             AEN+ G  S +  + V +K
Sbjct: 19370 AENSSGSKSATIKLKVLDK 19388



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)

Query: 19    VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
             VDP R+   P  +          + +  G + K +  + G P P + W +  Q +++  R
Sbjct: 22538 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 22589

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
               +      T SL +      D G Y  +A N +G R VTV + V        G  V+S 
Sbjct: 22590 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 22648

Query: 139   TLGDR 143
                ++
Sbjct: 22649 VTAEK 22653



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
             V+   + +      G P PE+ W        R+EG    +V  + G +Y  L +      
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 24088

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y     N+ G  S   T++V       + LAV EV    + ++ +  +I+G   V 
Sbjct: 24089 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 24148

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                +      R           YA  + +       +++        +  +AEN  G   
Sbjct: 24149 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 24196

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                 V V    + + +E   P  P K T            + D SQ + ++       PE
Sbjct: 24197 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 24237

Query: 654   VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
                 H+G           + +GT+         +C   V    +G    +  +A+N  G+
Sbjct: 24238 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 24293

Query: 704   VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
                + +       D T QP       + +   G+ + I   + G P P + W++DG+ L 
Sbjct: 24294 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 24352

Query: 763   KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             K T    V +      L +K+      G+Y +   N  G  +  +S+++
Sbjct: 24353 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)

Query: 1740  DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
             D S +    +A+E+   +P F   S+  + L V  G++        G P P V+W K D 
Sbjct: 26167 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 26225

Query: 1797  SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
              +R   +       D   SL I +   +D  KYT    N L  A+ T  L+V+ ++
Sbjct: 26226 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 26276



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 38    PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
             P   + ++ G+  K +  + G P P+VT  R+G P+ +  RF  +       ++ +    
Sbjct: 26482 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 26540

Query: 98    EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
               D G+Y   A N SG  +  + + V        G  V+S
Sbjct: 26541 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G+S+ I   + G P P V W +DG  + K   + E+       +L ++     H G Y +
Sbjct: 27973 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 28031

Query: 795   LLKNRVGECSCQVSLMLQNSSARAL 819
               KN  G    ++ + +Q++  + +
Sbjct: 28032 EAKNASGSAKAEIKVKVQDTPGKVV 28056



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)

Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
            +  H G        + +   P      + V V EG+    +C+V+  P   + W LNG+ 
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880

Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
            ++ +K   +  +G +  + I      D G  K  A+N  G  E   ++ +       S  
Sbjct: 1881 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1939

Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
             +APE    RP+  +      + +     +P   T  K  +  +  +    +KV   ES 
Sbjct: 1940 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1995

Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
            EL  K          + IT   +K RK+ +  E +                   K   +E
Sbjct: 1996 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2055

Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
             G K+TI         L+   E    +  +    +G    A   + VV KPDP       
Sbjct: 2056 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2109

Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
                       WY +            IE  D     W E   C      ++D+  +   
Sbjct: 2110 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2147

Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
               V+AIN+ G +        Q  +L T  ++ ++     KD +   + +  EP V  + 
Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2207

Query: 1452 VTINTEQKVSDFY 1464
                 E    D Y
Sbjct: 2208 YKDGMEVHEGDKY 2220



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)

Query: 935  PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
            P+ V E + K+   Q+ DFRSVL            + P P+   P+F     GK +   +
Sbjct: 1917 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1962

Query: 995  NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
                  +T   K V   K             + + K  E  + + +     T +    A 
Sbjct: 1963 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 2013

Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
                LKS  K+E  +++      +  H     T+ EK++   E + T P FK        
Sbjct: 2014 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2073

Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
                    +++Q   V +G     + +V   P     W  NG K  ++ +      E ++
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
            C + I     ED       A N AG+
Sbjct: 2134 CELVIRDVTAEDSASIMVKAINIAGE 2159



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + +   VSG PPP V W  N NE    ++   E      S+ I+       G Y+  
Sbjct: 16539 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 16596

Query: 697   AWNSAGEVRTQAVLTV 712
             A N AGE +   ++ V
Sbjct: 16597 AKNEAGERKKTIIVDV 16612



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
             T RD+  V  G   R   +++G P+P++ W K+ +  +RE R   +D  +D     L I 
Sbjct: 17913 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 17969

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCTA 1844
             +    D  KY   A NS G A  +A
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSA 17994



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 1749  VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
             V  E+  VK    K + DL+      V  G   R +  + G P PEV W KD  +   +R
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246

Query: 1803  HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               ++  D   + S   ++     D  KY   A N+ G     A + V
Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 22/92 (23%), Positives = 40/92 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G ++ +   V G P P   W    +E+  S      +  +   L I++V  +D+G
Sbjct: 18908 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 18967

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
              Y+  A NS+G    +  + V +     QP F
Sbjct: 18968 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 18999



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             + +  G + R    I+G P PEV W K D  IR++    +        SL++ +V   D 
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 23008

Query: 1827  AKYTCKAVNSLG 1838
              KYT    NS G
Sbjct: 23009 GKYTLTLENSSG 23020



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 1758  PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
             P     +   EVV+   G++ +    I G P P + W+KDD+ ++ +    ++   D   
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 26928

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
             S++I D    +   Y  K  N++G A+ T
Sbjct: 26929 SILIKDADRLNSGCYELKLRNAMGSASAT 26957



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V  + G   +    I+G+P P + W K +  LQ +A V V     +  + I   ++ + G
Sbjct: 26882 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 26941

Query: 230   VYTCLVVNGSGKASMSAELSIQGLD 254
              Y   + N  G A  SA + +Q LD
Sbjct: 26942 CYELKLRNAMGSA--SATIRVQILD 26964



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 2/77 (2%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            ++P + + ++D+ + EG      C+    P+ +  WF++ + ++     + + +   +  
Sbjct: 8743 IEPAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVH-K 8800

Query: 1816 LIISDVCGDDDAKYTCK 1832
            L I+DV  +D  +YTCK
Sbjct: 8801 LTIADVRAEDQGQYTCK 8817



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)

Query: 143   RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
             RF A   E R  +     PK  T    +VV  G+           P+ +  W K N PL 
Sbjct: 12982 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 13041

Query: 203   PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                  + +E+   ++LE     + D G Y  ++ N  GKA     L +
Sbjct: 13042 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 13086



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
             V+EG       KI G P P +TW K   P +P  +  V   +  N + V     L I   
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 16186

Query: 224   NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
              + D G+YT   VN  G AS    L++ G
Sbjct: 16187 RRSDTGLYTITAVNNLGTASKEMRLNVLG 16215



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
             G    L   ++G P P++TW    +     AR       ++L I++A  ED G Y+   E
Sbjct: 17233 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 17292

Query: 587   NALGQVSCSAWVTVHEK 603
             N  G  + S  V V +K
Sbjct: 17293 NPAGSKTVSVKVLVLDK 17309



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
             A+N  G +S  +  T   +    K EY  P     PT          L +  G  + +  
Sbjct: 20350 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 20400

Query: 644   VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             + + G P P+  W   G +I+ S+        T   L I+    +D G YT  A N  G 
Sbjct: 20401 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 20460

Query: 704   VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
                   +TV +      P  IS   +  A+L
Sbjct: 20461 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 20491



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             V  GS + + + +SG P P+V    +G  ++ +  F+ E      ++ ++E    D G Y
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 26547

Query: 694   TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
                A NS+G  +    ++ +  P   T P  IS
Sbjct: 26548 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)

Query: 1743  QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
             +AF   + +E P ++P    T    +++    GS    D  I G P P+V W  ++  ++
Sbjct: 28631 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 28689

Query: 1800  ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             E+    I   +D   +L + D    D  +Y     N+ G  T +  ++V
Sbjct: 28690 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F K + D  + +G     +    G P   V W K+  ++  S+   I   E  +  L I 
Sbjct: 7870 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIP 7928

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
                +D  +Y C   N+ G+ +C+A++++
Sbjct: 7929 SSTVEDAGQYNCYIENASGKDSCSAQILI 7957



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 1076  NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
             NC+    G  D    N K S      P      + L+DV V  G+     C++S +    
Sbjct: 12167 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 12225

Query: 1129  IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
             + W L GK L+ +  ++   EG + ++++     ED G  +  AK+
Sbjct: 12226 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 12271



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 438   SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
             SG PKP+V+WF +   V  ++    +     +  L  +KA+  DSG Y     N+ G   
Sbjct: 16843 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 16901

Query: 498   CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
                 + V       V P SF  V KD  VI
Sbjct: 16902 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 16931



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             ++  + G++  +   + G P PT+ WLR  K + +++   E+   +    L++K      
Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 23692

Query: 789   AGQYEILLKNRVGECSCQVSL 809
              GQY +   N  G  S  V++
Sbjct: 23693 GGQYILRASNVAGSKSFPVNV 23713



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 2/92 (2%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1816
            P F   +  L VV G  A     IEG     V W K+ ++ IRES + +I + E+   +L
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATL 5668

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              +     +  KY C+  N  G     A L+V
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDD 1825
            + V  G+    +C + G P+    WFKD + +  +S+H     ++  +  +  +++   D
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM--SD 6711

Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
               Y+ +  NS+G++ CT  + V
Sbjct: 6712 KGLYSFEVKNSVGKSNCTVSVHV 6734



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)

Query: 88    TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
             T S ++  + E    ++  +A N  G  + ++ L V                + D    P
Sbjct: 15351 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 15395

Query: 148   AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
              ++ R S+ G+           + VK G+       +TG P P++ W K    ++     
Sbjct: 15396 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 15445

Query: 205   ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
                 +  VS       L I    ++D G YT    N  G    +  + +    S  R+  
Sbjct: 15446 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 15505

Query: 261   VRETKA 266
             V + KA
Sbjct: 15506 VTDIKA 15511



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G +V     I G P PT  W  DG  + K   H+ V  +     L +K       G+Y+I
Sbjct: 17525 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583

Query: 795   LLKNRVGECSCQVSL 809
              + N  G  +  V L
Sbjct: 17584 TVSNAAGSKTVAVHL 17598



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
             EAP  +L P     L IK G T       + G P P+ +W + G+ I       +     
Sbjct: 20374 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              +   + +A  + D G+YT  ATN  G +   V++TV
Sbjct: 20434 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 20469



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
             G +  ++  V G P P +TW    Q ++  +       A    L+I + +  D G Y   
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
             A N +G+V     + VH+              P  PT PI
Sbjct: 21140 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 21166



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             I+ G + +    ++G P P+V W +    I      ++D     T SLV+  V+  D GK
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 23010

Query: 104   YTCEATNGSGARQVTVELTV 123
             YT    N SG +   V + V
Sbjct: 23011 YTLTLENSSGTKSAFVTVRV 23030



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P+  LP     +K     K +   +G P+  V W ++GQ +    R  +      T SL 
Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 25453

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I    +ED G Y    +N +G+  +TV +T+
Sbjct: 25454 IKEASKEDVGTYELCVSNSAGS--ITVPITI 25482



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 1782  EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P V W KD++++     + I+ + D +  L I  V  +D  KY     N +GE
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 27352



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 1084  TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
             +T    ++  +G  P  +    D+ + EGK L + C  + +P   + W+  G+ + + + 
Sbjct: 33315 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 33374

Query: 1143  -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
                 +     L ++ I     +D GLY     N+ G    +  + +
Sbjct: 33375 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
             F + L ++ V+E   + L C+VS  P A +IW    + +  T    +  EG    + I+ 
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 12523

Query: 1160  ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
             A  ED G Y C                                 R P S         +D
Sbjct: 12524 AHLEDAGNYNC---------------------------------RLPSS--------RTD 12542

Query: 1220  ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
               VK            +  + I  P++ ++  GE  E    ++  +     W +  K ++
Sbjct: 12543 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 12592

Query: 1280  ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
               +   V        L +  A  +  G Y ++V    G+ +A  +LTV++K
Sbjct: 12593 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 12639



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 16/82 (19%), Positives = 37/82 (45%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             ++ ++ G+    + + +G+P+P+V+W K    +    R  +        LE     + D 
Sbjct: 16827 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 16886

Query: 229   GVYTCLVVNGSGKASMSAELSI 250
             G Y  +V N +G      ++++
Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV 16908



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)

Query: 619   KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
             KP   + L G+  L V  G  + +   V G P PEV W    +  ++  S     + R  
Sbjct: 18200 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 18257

Query: 677   QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                  + +    D G Y   A N+AG     A + V
Sbjct: 18258 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
             +  +A+NA G +S  +  T      + K E  LP     P      +    + V  G   
Sbjct: 23593 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 23643

Query: 641   TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              +   V G P P + WL    EI+ES     +    +  L +++    D G Y   A N 
Sbjct: 23644 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 23703

Query: 701   AG 702
             AG
Sbjct: 23704 AG 23705



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + +K G   K    + G P P ++W ++G  I    R  +      T  L +      D 
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 25857

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
             G+Y     N +G R V V   V        G   ++    ++ S     P  +    I  
Sbjct: 25858 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 25917

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
                 K  T      + EG++   SCK+T         LKGN  +            +P  
Sbjct: 25918 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 25970

Query: 206   RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
              V++   +   V      LEI  V ++ + +  C     S   S  +   I+  +  +  
Sbjct: 25971 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 26028

Query: 260   FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
             +VR  K    D+R + T +      E ++ +  AA  S     S   R   P +     P
Sbjct: 26029 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 26084

Query: 315   QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
              PP + K+ +S K +   A   P+    +          + +       + S  G E   
Sbjct: 26085 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 26144

Query: 374   PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
                   A +  R      +G+ D  S +++ +I  E + +  F       ++  VK   +
Sbjct: 26145 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 26203

Query: 431   VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
                     G P P V W    T +R +   ++  +   S  L +  A   DSG Y+ T  
Sbjct: 26204 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 26260

Query: 491   NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
             N     S +  ++V          +   V K+ AV+
Sbjct: 26261 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 26296



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V++G + R +  I G+P P   W K    +   A ++ SE +    L I   ++ D G
Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 30203

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y  ++ N  GK ++  ++ + G
Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIG 30226



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
             P  +  +R   V  G   RF   ++  P  EV W+ +   ++ES   +I Y +  G  +L
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 32431

Query: 1817  IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              I D   DD   Y     N  GEA+  A L V
Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 1760  FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
             F   + D++V E   A+F+C++   P     W K  Q I     F++  D   + S++I 
Sbjct: 11842 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 11899

Query: 1820  DVCGDDDAKYTCKA 1833
                 +D+AKY  +A
Sbjct: 11900 SAAFEDEAKYMFEA 11913



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             R+VV  G + R    ++G+P P VTW      L   A +  +  +   V  I    +   
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 16590

Query: 229   GVYTCLVVNGSGK 241
             GVY+ L  N +G+
Sbjct: 16591 GVYSLLAKNEAGE 16603



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             ++ G   +    VRG P P+VTW + G    +  G   L+D        LVI     +D 
Sbjct: 18618 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 18673

Query: 102   GKYTCEATNGSGARQVTVELTV 123
             GKY+    N +G + V V + V
Sbjct: 18674 GKYSLTLVNPAGEKAVFVNVRV 18695



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             L V  G+    D  + G P P V W KD   ++ +   ++    +  C+L +  V   D 
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363

Query: 1827  AKYTCKAVNSLGEATCTAELIV 1848
               YT  A NS G  + T +L V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 615   VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             VA     AP + L+GL DL  +  + S   + + + G P P V W    + +        
Sbjct: 19972 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 20031

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
             E      +L + +    D G YT    N AG +  T ++  V +P   T P
Sbjct: 20032 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 20082



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)

Query: 142   DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
             D + AP +   P+I          K G  +V        +  I G+P P+ +W K    +
Sbjct: 20371 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 20420

Query: 202   QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             +PS    ++      +L I    + D G YT    N  G
Sbjct: 20421 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G ++ +   I+G P P V   RDG  L K T  F      +  T+ LK+     
Sbjct: 26485 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 26543

Query: 789   AGQYEILLKNRVGECSCQVSLML 811
             AG+YEI   N  G     +++++
Sbjct: 26544 AGRYEITAANSSGTTKAFINIVV 26566



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
             V+++   ++ V+K  A   G    L+  + G P P I W  + + +Q     C      +
Sbjct: 26871 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 26927

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
             A + I+DA   + G Y     NA+G  S +  V + +K
Sbjct: 26928 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 26965



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 1/82 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            ++V  G  A  +  + G P+ +  W+KD + +  S+ ++I + ++    L        D 
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDS 4084

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
             +YT +  N +G ++C     V
Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)

Query: 437   VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
             V   P+    W   G PV   +  +   E+ G  Y             Y   A N QG  
Sbjct: 13624 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 13670

Query: 497   SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
               S  T +++ +   E    F  V  L    V  G    L  +V G P P+ITW      
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730

Query: 554   I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
             + Q  R T E     + + I D+   D GTY   A N  G+ +    V V +K
Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 13783



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 16/67 (23%), Positives = 28/67 (41%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G    +   + G P P + W+    E+  +     +      SL +++    D+G Y  +
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 22617

Query: 697   AWNSAGE 703
             A N AGE
Sbjct: 22618 AKNVAGE 22624



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)

Query: 395   VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
             +SK ++   P+  + +   P+    P+ ++   V   +T +   +V G P P + W L G
Sbjct: 23604 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 23662

Query: 452   TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
                  +    E+        L +  A   D G Y   ASN  G  S
Sbjct: 23663 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 23708



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++  AT +    ++G PEP+V W +    +T   +      +  +F+ LVI  V   D G
Sbjct: 25119 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 25174

Query: 103   KYTCEATNGSGARQVTVELTV 123
             +Y     N SG++   V + V
Sbjct: 25175 RYNLTLENNSGSKTAFVNVRV 25195



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             +KP          V      + D   +G P   V W KD Q+++E+    +   +    S
Sbjct: 25393 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 25451

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   +D   Y     NS G  T    +IV
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 47/193 (24%), Positives = 71/193 (36%), Gaps = 18/193 (9%)

Query: 1666 PWLMKDTKNMEAKKLSKDRMKKYMA-----RRKWQKTGNAVRAIGRLSSMAMISGLSG-- 1718
            P+  K  +N+++      R+   +A     R  W K G  + A  R   +A + G +   
Sbjct: 4113 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR-IAFVEGTASLE 4171

Query: 1719 --RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR 1776
              R     +      A      +D S A +  V E    V    SK     +V+ GSA  
Sbjct: 4172 IIRVDMNDAGNFTCRATNSVGSKDSSGALI--VQEPPSFVTKPGSK-----DVLPGSAVC 4224

Query: 1777 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1836
                 +G     + WFK ++ +       I   E    SL +  V   D   YTCK  N 
Sbjct: 4225 LKSTFQGSTPLTIRWFKGNKELVSGGSCYIT-KEALESSLELYLVKTSDSGTYTCKVSNV 4283

Query: 1837 LGEATCTAELIVE 1849
             G   C+A L V+
Sbjct: 4284 AGGVECSANLFVK 4296



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 5/97 (5%)

Query: 1720 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKT-IRDLE---VVEGSAA 1775
            K S    T  L  E++E  E   + F E V+  +  +      T I+D+E   V++ + A
Sbjct: 8614 KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA 8673

Query: 1776 RFDCKIE-GYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
             F+  I+  YP+ ++ W+K  + +  S  F+I  D D
Sbjct: 8674 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 8710



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 45/214 (21%), Positives = 87/214 (40%), Gaps = 40/214 (18%)

Query: 879  TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLK-EIPA----------EQMDFRA 927
            +R+  EE ++  +V ++  + ++ +K S   + E+ ++ ++PA          E+M F +
Sbjct: 9193 SRRMEEEKVQVTKVPEVS-KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251

Query: 928  NLQRQVK---PKTVSE--EERKVH---------SPQQVDFRSVLAKKGTSKTPVPEKVPP 973
            + + +V    P+   E   E K+H          P+  +     A +  +  P+P+KV P
Sbjct: 9252 HTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEP 9311

Query: 974  PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQ-PSGPLKPVGNAKPA 1032
            P P  P+       KK +P E             V   +P +  + P  P KPV   K  
Sbjct: 9312 PAPKVPEV-----PKKPVPEEK--------KPVPVPKKEPAAPPKVPEVPKKPVPEEKIP 9358

Query: 1033 ETLKPMGNAKPAETLKPMGNAKPDENLKSASKEE 1066
              +     A PA+  +       +E +   ++ E
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQRE 9392



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 25/139 (17%)

Query: 136   VSKTLGDRFSAPAVETRPSIWGECPP--------------KFATKLGRVVVKE----GQM 177
             V K       A   + RP   GE PP              KF  ++  +++ E    G  
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSS 11135

Query: 178   GRFSCKITGRPQPQVT-WLK--GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
               F C ++  P   +T W+K   N+   P  R     K+  + L I  V   D G YTC+
Sbjct: 11136 AIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKD--RKLHIIDVQLSDAGEYTCV 11191

Query: 235   VVNGSGKASMSAELSIQGL 253
             +  G+ + + +A+L ++ L
Sbjct: 11192 LRLGNKEKTSTAKLVVEEL 11210



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 1764  IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             ++D  V E     F+C++      +  WF+++++I +S  + I   +D   +L I D   
Sbjct: 12646 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 12703

Query: 1824  DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
             DD A Y     N  GE     A LIVE
Sbjct: 12704 DDQANYNVSLTNHRGENVKSAANLIVE 12730



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 411   SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
             +A PK ++  Q   V   + +         PK E  WF E  P+  +  +I+   +  S 
Sbjct: 12997 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 13053

Query: 471   YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
                +L+A+  D G Y     N  G+      L+       V  L V E      S+  + 
Sbjct: 13054 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 13112

Query: 524   AVIEGQDFVLQCSVRGTPVPRITWLL 549
              + +G   ++   V    + R TW+L
Sbjct: 13113 PLTDGGSKIIGYVVERRDIKRKTWVL 13138



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)

Query: 2     GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
             G+  L   S  +K  +S DPS +   PLT   AF+ P  +L   K+G        +    
Sbjct: 13359 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 13416

Query: 58    ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
                GYP P  TW    + + +G R  +   +     LVI      D+G YT +  N
Sbjct: 13417 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 13471



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
             G + VK G   R    + G+P P+V W K      L  S RV +  +       +    +
Sbjct: 18209 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 18268

Query: 226   DDVGVYTCLVVNGSGKASMSAELSI 250
              D G Y     N +G     A +++
Sbjct: 18269 SDGGKYVVTATNTAGSFVAYATVNV 18293



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 1761  SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
             S+  + + V  G +AR     +G P PE+ W +++    +    ++  ++  N + +  D
Sbjct: 24028 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 24083

Query: 1821  VCGDDDA-KYTCKAVNSLG 1838
              C  +DA KY  K  NS G
Sbjct: 24084 NCDRNDAGKYILKLENSSG 24102



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)

Query: 21    PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
             P  V    + E P + L  R    + +++G   +    ++G P P   W + GQ I+   
Sbjct: 30122 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 30179

Query: 78    RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
             R ++      T  LVI      D G Y     N  G + V +++ V GS
Sbjct: 30180 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 30227



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G  + I   ++G P PTV W  + + L ++     +       ++V+K  Q  H 
Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 16590

Query: 790   GQYEILLKNRVGE 802
             G Y +L KN  GE
Sbjct: 16591 GVYSLLAKNEAGE 16603



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)

Query: 537   VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             +RG PVP   W  +G  I   ++     +   + L I++ L  D G Y     NA G  +
Sbjct: 17534 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 17593

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              +  +TV +              P  PT PI         ++D +   MT  +S  PP +
Sbjct: 17594 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 17630



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
             G A R +  + G P P + W KD + +  +   +I    D + +L+  D    D   YT 
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 21534

Query: 1832  KAVNSLGEA 1840
              A N  G A
Sbjct: 21535 TATNPGGFA 21543



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)

Query: 20    DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
             +P+ V   P  E    +LPP         + + I+   T +    ++G P P+V W R+ 
Sbjct: 21841 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 21898

Query: 71    QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                   G  L    I  T S   L++  V+  D GKY     N SG++   V + V
Sbjct: 21899 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 21948



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G  + + V + G P PEV W     EI+++         T  SL +  V   D+G
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 23009

Query: 692   TYTCEAWNSAG 702
              YT    NS+G
Sbjct: 23010 KYTLTLENSSG 23020



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)

Query: 17    LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
             +++ P  V  + +T E     +P   + ++ G     E   +G P+P ++W ++G P+  
Sbjct: 27547 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 27606

Query: 76    GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                F+         +L I    +E  GKYT    N     ++ V +TV
Sbjct: 27607 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 27651



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)

Query: 1745  FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
             + E++AE    ++P     I DLE+ +          G++ R    + G P P + W K 
Sbjct: 29428 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 29482

Query: 1795  DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
              Q I  +    ID  E  +  LI+  V   D  KYT +A N  G+ + T
Sbjct: 29483 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 29529



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 3/132 (2%)

Query: 916   KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTP-VPEK-VPP 973
             KE+  E++ F   +   V+   V EEE  +H  ++      +      K P VP K VP 
Sbjct: 9901  KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960

Query: 974   PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAE 1033
              K   P  +       K+P E      E +     +  KP     P  P KPV   K   
Sbjct: 9961  EKKPVPVPKKKEAPPAKVP-EVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPV 10019

Query: 1034  TLKPMGNAKPAE 1045
              +     A PA+
Sbjct: 10020 PVPKKVEAPPAK 10031



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)

Query: 1760  FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
             F   + D  V EG  A F C++  +    VVWFK+D  +  SR   I   E     L + 
Sbjct: 11576 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 11633

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             +V  DD ++   +    + E + TA+L V
Sbjct: 11634 EVTLDDISQIKAQ----VKELSSTAQLKV 11658



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 1760  FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
             F   ++D+   E  +A F  ++  + +  V WFK+DQ +  +R   +  DE    S+   
Sbjct: 11931 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 11988

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCT 1843
             D+  DD ++   +A+    EA  T
Sbjct: 11989 DLSIDDTSQIRVEAMGMSSEAKLT 12012



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/72 (27%), Positives = 32/72 (44%)

Query: 185   TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
             TG P+P  TW  G+  L+   RV +   +    L I    + D G+YT  + N     S 
Sbjct: 13419 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478

Query: 245   SAELSIQGLDSA 256
               ++++    SA
Sbjct: 13479 EIDVNVIARPSA 13490



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 10    SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
             S IS+  ++ DP           P   L   ++ + EG         R  P P V+WH++
Sbjct: 14372 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 14423

Query: 70    GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
             G+ + +  R  +          V  +V   D G YT    N  G+   ++ + V G
Sbjct: 14424 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 14478



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
             G    L+  VRG P P + W  +       RS        A  ++  +  A   D G Y 
Sbjct: 18216 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 18275

Query: 583   CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
               A N  G     A V V +K    ++  ++ V+  + T
Sbjct: 18276 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 18314



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 40    RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
             + L ++ G T +    V+G P P++TW +    +    R  LD  I+ T F   +    V
Sbjct: 19701 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 19756

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
             ++ D GKY     N  G ++ T+ + V
Sbjct: 19757 NKYDAGKYILTLENSCGKKEYTIVVKV 19783



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             VK V     S  S S DP         E P F +     + L +K GA+       RG P
Sbjct: 26157 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 26214

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P V W +    + +  R  +D     T SL I   +  D GKYT    N   A  +T+ 
Sbjct: 26215 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 26271

Query: 121   LTV 123
             + V
Sbjct: 26272 VKV 26274



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)

Query: 517   SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
             S + K   V  G  F +    RG PVP + W    +P    R+       +    L I++
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 26246

Query: 573   ALPEDHGTYTCLAENALGQVSCSAWVTV 600
             A   D G YT   +N L   S +  V V
Sbjct: 26247 ANRNDSGKYTLTIQNVLSAASLTLVVKV 26274



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             L V  G+  TMTV   G P P V+W     +++     + +   ++ SL I+     D+G
Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 26253

Query: 692   TYTCEAWN 699
              YT    N
Sbjct: 26254 KYTLTIQN 26261



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G  KL+     +  +LSV+  ++           I   R+L   E     FE  +  +  
Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2560

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W+   + I    ++ ++   +  + L +  + ++D GKYT  A    G    + +L
Sbjct: 2561 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2615

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
            TV G          +SK L D+                            V E Q   F 
Sbjct: 2616 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2640

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C++   P  +  WL+    L  +  +        + L I     DD+G YT  V      
Sbjct: 2641 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2699

Query: 242  ASMSAE 247
            A +  E
Sbjct: 2700 AKLKVE 2705



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)

Query: 1725  SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
             S T  +++E    + ++ +  L+ +++ K  VK              PYF+  + D   V
Sbjct: 11616 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 11675

Query: 1771  EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
             E       C++    D  V WFKD + I  S  + I  D      L I      D  +Y 
Sbjct: 11676 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 11732

Query: 1831  CKAVNSLGEATCTAE 1845
             C       +A  T E
Sbjct: 11733 CDCGTDKTKANVTVE 11747



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)

Query: 442   KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
             K EV W L    V  Q    ++  +   H L +   + RD G Y   A + + +      
Sbjct: 12939 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 12995

Query: 502   LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
                     +  AP   +  +D  V  G+   +       P     W    +P+       
Sbjct: 12996 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 13047

Query: 562   EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
              A      I +A   D G Y  + +N  G+
Sbjct: 13048 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 13077



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
             + V  G+ + +   V+  P   I W+ N   + K T  + +++E      +   +SI KA
Sbjct: 15408 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 15467

Query: 1161  LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
             + ED+G Y   A N  G    +  V V D P+
Sbjct: 15468 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R+  +  G   R    I+G P P+V W K+D+        +ID    G+  L I +   +
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 17282

Query: 1825  DDAKYTCKAVNSLGEATCTAELIV 1848
             D   Y+    N  G  T + +++V
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
             +D  V++ G+   +   + G P+P I+W  +G  I+  R+  E    + H    ++D + 
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 25854

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y    +N  G  S +    V +K             P  P  P+ + GL+
Sbjct: 25855 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 25896



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++ GA+ +     +G P P   W +    ++       D     +FS L +   +  D G
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 28424

Query: 103   KYTCEATNGSGARQVTVELTV 123
             KYT    N SG++ +T  + V
Sbjct: 28425 KYTLTVENNSGSKSITFTVKV 28445



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            + D +V EG   + + K+      E VW KD Q ++ S    I  D+  +  L+I D+  
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419

Query: 1824 DDDAKYTCKAVNSLGEAT 1841
            +D   Y+   + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F K + D  V  G +   +    G     V W KD  +I  S    I   E   C L I 
Sbjct: 5988 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK-TCILEIL 6046

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            +    D  +Y+C+  N  G   C A  +V T+E
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGA--LVSTLE 6077



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 50/218 (22%), Positives = 85/218 (38%), Gaps = 16/218 (7%)

Query: 860  WLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIP 919
            W   E+ E V   + R  E  +  E  + + EV +     ++ +K+   +      K + 
Sbjct: 9495 WSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIIS------KRVE 9548

Query: 920  AEQMDFRANLQRQV--KPKTVSE-EERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKP 976
            AE  +     ++++  KPK  ++ EE       +   + V  KK  +  P  EKVPPPK 
Sbjct: 9549 AEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPK- 9607

Query: 977  ATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKP-AETL 1035
              P+       +KK+P +      E L AK  E    ++  +          A P A   
Sbjct: 9608 -VPEEPKKPVPEKKVPPK-VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVP 9665

Query: 1036 KPMGNAKPAE---TLKPMGNAKPDENLKSASKEELKKD 1070
            +    A P E    LKP    +P   +    K  +K++
Sbjct: 9666 EEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 76/338 (22%), Positives = 111/338 (32%), Gaps = 62/338 (18%)

Query: 932   QVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSK--------TPVPEKVPPPKPATPDFRS 983
             +V  K V E++  V +P++V+       +   K        TPVP+KV  P P  P  R 
Sbjct: 10034 EVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE 10093

Query: 984   VLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKP 1043
              +     LP E      E +    V   + L   +   P +     +  E L       P
Sbjct: 10094 PVPVPVALPQEEEVLFEEEI----VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP 10149

Query: 1044  AETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQK 1103
              E   P       E  +   +EE+  +VK  V                      P  K+K
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV----------------PVPAPVPEIKKK 10193

Query: 1104  LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI------ 1157
             + +  V   KK          PPA +            K IIL +E  +  V +      
Sbjct: 10194 VTEKKVVIPKK-------EEAPPAKV---PEVPKKVEEKRIILPKEEEVLPVEVTEEPEE 10243

Query: 1158  ----EKALPEDRGLYK-----------CVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202
                 E+ +PE+    +            V K    +A       V+  PA  + K PE K
Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303

Query: 1203  SRRP--KSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238
                P  K   PP    E    V +K     P K A+PP
Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKV-LVPKKEAVPP 10340



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
             G ++ +   +   P     W  +GK  K  K  +        L    +   + I +    
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884

Query: 1164  DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
               G Y   AKN AGQ   +C+V V D P
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKVMDVP 15912



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
             GS    D  + G P+P+++W K D+ +       + Y   G  +  +   C   D  KYT
Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 29119

Query: 1831  CKAVNSLG 1838
                 N+ G
Sbjct: 29120 LTVKNASG 29127



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 1765  RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
             ++LE++EG  A F C I  E +P   V W +DD+++     + +  D      L++ D  
Sbjct: 12559 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 12614

Query: 1823  GDDDAKYTCKAVNSLGEATCTAELIV 1848
               D   Y    V  +G A   A L V
Sbjct: 12615 LQDMGTY----VVMVGAARAAAHLTV 12636



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 614   PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             P+      AP  + L     L +  G    +T + SG P P+V W  +  ++ E +  H 
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867

Query: 672   EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
               + T  +L ++++  +  D+G Y     NS G
Sbjct: 16868 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 16898



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
             KD  +++ G+ F L+  V G P P + W  +G+ ++   +  E  +A+    L  +D+  
Sbjct: 21468 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 21526

Query: 576   EDHGTYTCLAENALG 590
              D G YT  A N  G
Sbjct: 21527 RDSGAYTLTATNPGG 21541



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
             G +  +   + G P+P++T   +G P++          AE   +++++++  D G Y   
Sbjct: 26491 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 26550

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
             A N+ G       + V ++             P  PT P+ +  +++  V          
Sbjct: 26551 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 26597

Query: 636   DGSQVT 641
              GSQVT
Sbjct: 26598 GGSQVT 26603



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P   + L+    +K   G+ V +   +SG P P + W  +  E+Q +     E      S
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 26929

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
             + I++    ++G Y  +  N+ G     A + VQ
Sbjct: 26930 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 26961



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             +P + + +  G   +    + G P P  +W   G  +    R  ++   +    L I   
Sbjct: 29743 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 29801

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
                D G+YT E  N +G    T+++ +
Sbjct: 29802 TIRDTGEYTLELKNVTGTTSETIKVII 29828



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            F++ ++D+   E  + A F+C+    P  +V W+KD   + E   +++  D   +  L I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2233

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +   D   Y+C  V      T TA+LIVE
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)

Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
            W K G  V+        I + S M +I  ++  K   G+ +  + A  L +   VS   +
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2445

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            + +              ++D+ V+EG+ A  +CK+       V W+ +D+ I+     Q
Sbjct: 2446 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
             ++R L +V  G   R    + G P P+V W K   D  +R+    Q+D   D    L+I 
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 18666

Query: 1820  DVCGDDDAKYTCKAVNSLGE 1839
             +   DD  KY+   VN  GE
Sbjct: 18667 NSTRDDSGKYSLTLVNPAGE 18686



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 728   RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
             R++    G S+ I   I G P P V W +D   L K+  + E   N + FT L++ +   
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 20839

Query: 787   WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
             +  G++ + ++N  G+ S  V++ + ++    L
Sbjct: 20840 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 20872



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             +D+ VV  G     +  I G P P+VVW KD + + E+             +L++ D   
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773

Query: 1824  DDDAKYTCKAVN 1835
              D  +Y  K  N
Sbjct: 24774 TDGGQYILKLSN 24785



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
             K G+    +  + G P P+VTW      +    R  +    +   +L +      D G+Y
Sbjct: 28660 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 28718

Query: 105   TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
                  N +G +  +V + V G      G   VS          + E+    WGE      
Sbjct: 28719 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 28770

Query: 165   TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
             T++   +V++ + G  + ++      R Q +VT L     ++ S RVS   + G+
Sbjct: 28771 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 28823



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 1771  EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
             E S  R    I+G P P V W K +  +       ++     N +LI+ D    D  KYT
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 20054

Query: 1831  CKAVNSLG--EATCTAELI 1847
                 N  G  E T + +++
Sbjct: 20055 ITLKNVAGTKEGTISIKVV 20073



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 19/80 (23%), Positives = 30/80 (37%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V   +T     ++ G P P+V W  +G  +      +E+        L +      D G 
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y    SN  G  S   T++V
Sbjct: 24779 YILKLSNVGGTKSIPITVKV 24798



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
             G    +   + G P P+V+W  +G E++E+     E + T  + +L +++    D G Y 
Sbjct: 24722 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780

Query: 695   CEAWNSAG 702
              +  N  G
Sbjct: 24781 LKLSNVGG 24788



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 8/91 (8%)

Query: 1158  EKALPEDRGLYKCVAKND--AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
             EK +P  +   K V + +  A   E   ++ V+     E  + PE + R P + +P VL 
Sbjct: 10447 EKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE-----EKVRVPE-EPRVPPTKVPEVLP 10500

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPED 1246
              +     KK P P      A PP++ + P++
Sbjct: 10501 PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE 10531



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)

Query: 1076  NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
             NC+   + T    K  E    A  F  K Q++ + EG+K    C +S +    + W  + 
Sbjct: 12533 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 12588

Query: 1136  KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
             KTL++     +  +G    + ++ A  +D G Y  +     G A  +  +TV
Sbjct: 12589 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 12636



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R L V  G + R    I+G P PEV W KD+ +++   + +   + +    LII +    
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 20840

Query: 1825  DDAKYTCKAVNSLGE 1839
             D  K+     N  G+
Sbjct: 20841 DTGKFVMTIENPAGK 20855



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
             L V  G  + + V + G P PEV W      L N   I+ +E F          L I E 
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 20837

Query: 686   FPEDTGTYTCEAWNSAGE 703
                DTG +     N AG+
Sbjct: 20838 NRYDTGKFVMTIENPAGK 20855



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
             G   + +  + G P P V W K DQ +++++  +++++     +++ I++    D   Y 
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 21137

Query: 1831  CKAVNSLGE 1839
               A N +GE
Sbjct: 21138 LTARNIVGE 21146



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G++  +   ++G P PT+ W +DGK L + T   E+   +    LV K      
Sbjct: 21470 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 21528

Query: 789   AGQYEILLKNRVG 801
             +G Y +   N  G
Sbjct: 21529 SGAYTLTATNPGG 21541



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD+ VV+ G   + +  I G P P + W KD   I E    +I    D +  L + D   
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 25854

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y     N  G
Sbjct: 25855 RDTGQYVLTLKNVAG 25869



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 19/71 (26%), Positives = 30/71 (42%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V V+ G   +    I+G+P P+VT  +  VPL+ + R +         + +      D G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545

Query: 230   VYTCLVVNGSG 240
              Y     N SG
Sbjct: 26546 RYEITAANSSG 26556



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
             G++ R     +G P P  VW K D ++      + D     + S +  + C  +DA KYT
Sbjct: 28372 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 28427

Query: 1831  CKAVNSLGEATCT 1843
                 N+ G  + T
Sbjct: 28428 LTVENNSGSKSIT 28440



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 525   VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
             V +G    L   ++G P P   W   GQ I + A         EL I++A   D GTY  
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 30207

Query: 584   LAENALGQ 591
             + EN  G+
Sbjct: 30208 VLENKCGK 30215


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score =  295 bits (755), Expect = 3e-79
 Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)

Query: 1097  APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
             AP FK++L++++V       L C+V+  P   + W   GK +     K+ I   +G    
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
             + I     +D  +Y+  A N  G    +  + V+                          
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24715

Query: 1215  GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                             P K  +P  +        +R GE V +    +G      TW K 
Sbjct: 24716 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24759

Query: 1275  RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
             +  I  + H +V  + + + L       ++  G Y +  +N+ G  Q  V L V D PDP
Sbjct: 24760 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24819

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
             P G    SD+   S+ L+W   + DGGS + +Y +E   +  + W  +   R T + V +
Sbjct: 24820 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24878

Query: 1394  LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
             L     Y+FRV A N +G S+PS+ SE T   E      +  E  D+     EV     +
Sbjct: 24879 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24935

Query: 1454  INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
              ++ +++ + Y I E LG G+FG V R VE  ++K +  KF K     ++  +++EISI+
Sbjct: 24936 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24994

Query: 1514  NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
             N   H  ++   ++FE    +VM+ E +SG ++FERI    FEL ERE + Y+ Q+ E +
Sbjct: 24995 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 25054

Query: 1574  EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
             +++H   I H D++PENI+   +  + IK+I+FG AR+L+   + ++LF  PE+ APEV 
Sbjct: 25055 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25114

Query: 1634  NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
              ++ +  ATDMWS+G + Y+L                                       
Sbjct: 25115 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25174

Query: 1655  ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
                         +R+  ++ LQHPWL +  + +  K +   + ++Y      +K  N V 
Sbjct: 25175 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25233

Query: 1703  AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
             +  R+S    I      +S  G   + +    +E    VS   + AV EE  HVK     
Sbjct: 25234 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25281

Query: 1763  TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
                           + CKIE Y    +V W+   + +  S  ++I Y EDG   L + D+
Sbjct: 25282 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25326

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
                DD  Y CK VN  GE +  AEL V+ + E
Sbjct: 25327 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25358



 Score =  164 bits (416), Expect = 6e-40
 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)

Query: 63    QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
             +VTW+++G+ +   G F       GT+ L I+ + E D+G+Y CE +   G  +  ++  
Sbjct: 26443 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26502

Query: 123   VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
              +            S  K+  Q     T+  +    A E   S      P   T L    
Sbjct: 26503 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26557

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V    + +F+ K TG P+P   W K    +    +  +SE  G   LEIH  +  D G+Y
Sbjct: 26558 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26617

Query: 232   TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
             TC V N +G  S S +L+I+ +       V   K +       + V++E++    +  ++
Sbjct: 26618 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26677

Query: 286   DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
                EA ++         SK   S +   S   +          +K     +  RT  +  
Sbjct: 26678 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26737

Query: 337   VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
                 T  SI  +  R+  +    G         GV   + EE +        T   +Q  
Sbjct: 26738 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26795

Query: 389   LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
                + +   +SK     +  +      +  S  P F S+P+SQ + E Q V F CE+SG 
Sbjct: 26796 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26855

Query: 441   PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
             P PE+ WF    P+     ++ +      + L +  A   DSG Y+  A N +GQ  CS 
Sbjct: 26856 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26912

Query: 501   TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
             T  +  L ++E  PS   VL+        D  LQ S             + Q +Q + S 
Sbjct: 26913 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26954

Query: 561   CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
              EA  +      A       +  ++  ++        ++S S+++ +        S   +
Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 27014

Query: 614   PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
               A  +   P      SD+ + +G  +T+    +G P PEV W   G +I  QE   FH 
Sbjct: 27015 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 27074

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             E      +L I +V  +D G YT    N  G
Sbjct: 27075 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27105



 Score =  158 bits (400), Expect = 4e-38
 Identities = 188/837 (22%), Positives = 311/837 (37%), Gaps = 176/837 (21%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+   VA  + S  +L V+          E P  +   + + ++ G  A+F   + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221

Query: 62   PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P+++W++  Q +++G +  FL D      ++L++     ED   YTCEA N  G    + 
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             L+VE                      P V +        PP   T L   V  EGQ  R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F C+++G    +V+W   +  ++PS    +++      LEI     +D G YT +  N  
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376

Query: 240  GKASMSAELS--IQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
            G+ S +A LS  +Q LD          +++  DVR+   +    +S     E+    K  
Sbjct: 3377 GQVSSTANLSLEVQALD---------RQSSGKDVRESAKSQAVADSSFTKEESKISQKEI 3427

Query: 298  SSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP- 356
             S Q G S  +                         +  V +  S S    AA VQ    
Sbjct: 3428 KSFQ-GSSYEY-------------------------EVQVFESVSQSSIHTAASVQDTQL 3461

Query: 357  -RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
                 L  ++ S E  K  A  + +T    +  L  QDV  K  +               
Sbjct: 3462 CHTASLSQIAESTELSKECA--KESTGEAPKIFLHLQDVTVKCGD--------------- 3504

Query: 416  FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                          T +F C +      +V W  EG  +   E  ++  ++    +L + 
Sbjct: 3505 --------------TAQFLCVLKDDSFIDVTWTHEGAKIEESE-RLKQSQNGNIQFLTIC 3549

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
              +  D G YSC   N  G+ + S        AV+ V  +  S+L +             
Sbjct: 3550 NVQLVDQGLYSCIVHNDCGERTTS--------AVLSVEGAPESILHE------------- 3588

Query: 536  SVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQD-ALPEDHGTYTCLAENALGQVSC 594
                    RI   +  +  +++ S   A    LH  +  L + + T   L+E+       
Sbjct: 3589 --------RIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSES------- 3633

Query: 595  SAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
                 V+  K   + E          T PIF++ +S+  +  G   T++V V G P P++
Sbjct: 3634 ----PVYPTKFDSEKE---------GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKI 3680

Query: 655  IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ- 713
             W  NG  +  S D+ F   G  HSL I     ED G YTC A N  G+    A L +  
Sbjct: 3681 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3740

Query: 714  --EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 754
              E H  T+                 P F+ + + +  + G   +    + G+P PTV W
Sbjct: 3741 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTW 3800

Query: 755  LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             ++ K LC    +  +       T ++   Q   +G Y    +N +GE +C   L++
Sbjct: 3801 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857



 Score =  134 bits (336), Expect = 1e-30
 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)

Query: 396   SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
             S    +  P   +  S+ P   +  Q   V  +   KF  + +G P+P   W  +G  + 
Sbjct: 26529 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26588

Query: 456   RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
              Q G  ++ ED G  +L + K  T DSG Y+CT  N+ G +S S  L ++          
Sbjct: 26589 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26637

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
                 +KD    E Q    Q +   TP  +   ++  +  Q A  + E  ++E   Q+ L 
Sbjct: 26638 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26689

Query: 576   -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
              ++  +   ++E      + S   + VHE+  K+S+ SE +   A  K  +       + 
Sbjct: 26690 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26742

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + + +G ++ +   ++G    +V W+ NG E+  SE++ +   G+  +L I++    D G
Sbjct: 26743 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26800

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
               TC +    G V+ Q  LT+ +      P FIS+PRS   + GQ+VL +C I+G+P P 
Sbjct: 26801 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26859

Query: 752   VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             + W ++   +   + +  + ++ +V++L ++      +G+Y I  KN  G+CS   SLM+
Sbjct: 26860 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918

Query: 812   QNSSARALPRGREPA 826
                    LP   EP+
Sbjct: 26919 -------LPLVEEPS 26926



 Score =  122 bits (306), Expect = 3e-27
 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G  + ++  I G PFP   W ++G+ + K      +  +E    LV+K+     +G Y++
Sbjct: 23846 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23902

Query: 795   LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
             +L+N+ G+ +  + + +  S     P G  P   +D+    V       AD GG+D  G 
Sbjct: 23903 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23958

Query: 849   LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
             +          W   +    VRG        +++ E   R     Q      L  +  V+
Sbjct: 23959 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 24016

Query: 907   TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
              KT L+  +    P E +D   +       +   +   +V +   ++ +     K    +
Sbjct: 24017 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24075

Query: 964   KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
             KT +   +       PD       + ++ A+N    +ET  A + V    P       G 
Sbjct: 24076 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24131

Query: 1023  LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
             L+ +  +K + TL   KP     K             D   K ++KE +K          
Sbjct: 24132 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24191

Query: 1071  ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
                        +N+    R    T  + K   + G AP  +++++DV    G+   L CQ
Sbjct: 24192 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24250

Query: 1121  VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
             +   P   I W   GK L  ++   +S +G   ++++     ED G+Y C+A N+ G+ E
Sbjct: 24251 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24310

Query: 1181  CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
              S ++ +   P                                    P  P K       
Sbjct: 24311 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24330

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
                 E      G ++ L     G      TW   +K +Q SE++ +EN+E+ + L +   
Sbjct: 24331 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24386

Query: 1300  ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
              R+ H G Y + + N  G+  A +++ + DKPD P G      +  +S  +SW   + DG
Sbjct: 24387 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24446

Query: 1360  GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GS + +Y +E  ++     W+ +++  S T+  + +L  +  Y FRV A N +G S+P +
Sbjct: 24447 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24506

Query: 1418  ESELTTVGEKPEEP 1431
              S +  +    E+P
Sbjct: 24507 VSSVVIIKSPFEKP 24520



 Score =  118 bits (295), Expect = 6e-26
 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)

Query: 621  TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
            T P  + GL ++ V++G  VT+   +SG P P V W     +I+ S DF    +     L
Sbjct: 895  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954

Query: 681  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
             I+E F ED+G +TC A N AG V T   L VQ                           
Sbjct: 955  MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014

Query: 715  ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
                           P +   P+FI+KP       G SV+  C + G+P P V+W + G 
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074

Query: 760  ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             L   TG+ ++V  N+      LV+       AG+Y I+++N+ GE S   SL L+ +  
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131

Query: 817  RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
              L + ++    +      V        + G   PG+  +  +   E+E     + + K 
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186

Query: 876  RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
             V  R + E+    QE     F + L K++     KT  E+ L+E   E+M    +    
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242

Query: 933  VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
            V+    S  + ++ + + ++   V      S  P+P        +++   +    DF   
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298

Query: 982  -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
             R+ L     LP + G  +A   N K         NA  SG     P  P+G      TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350

Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
            +P+   +   +L P   ++    +  A     +         +       +    S+ + 
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407

Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
               P F  K       EG+      +V   P     W  +G+ +    T  +++ ++G+ 
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
             S+ I  A P D G +  VA+N AG++  S  +TV+                        
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504

Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
                                +  + P  ++  ++  ++ G  +E+  + TG       W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544

Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
            K    I   ++  +++E ++  + L I +   +    YT    NK G  + + +VN+ V 
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
              +P+P      P GT  A +I +  L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631



 Score =  115 bits (288), Expect = 4e-25
 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
             + E Q +  +  ++G    +V W L G  +   E     Y  +GS     +K A  RD G
Sbjct: 26745 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26800

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
               +C +   +G + C + L + +   +  AP+F S  +   + EGQ+ +  C + G P P
Sbjct: 26801 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26858

Query: 544   RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              I W  N  PI  + +        V  L I++A   D G YT  A+N  GQ S +A + V
Sbjct: 26859 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918

Query: 601   HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                         LP+   +P+  + L+   D   + GS  + +VQ+S +         + 
Sbjct: 26919 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26964

Query: 661   NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
             +      +  F     Q    +QE F E + +      N   ++ +     ++    G  
Sbjct: 26965 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 27023

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
             P   + P  ++   G+ + ++CA  G+P P V W   G+ +  ++ G F +   +D+ TL
Sbjct: 27024 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 27083

Query: 780   VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
             ++  VQ    G Y + L N  G  S  V++ +++
Sbjct: 27084 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27117



 Score =  115 bits (287), Expect = 5e-25
 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)

Query: 163  FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
            F +++    + EG    F CK++G P P++ W K         R+   E+  M  L+   
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297

Query: 223  VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
                             G+AS+   + +   +    +F    K           N I   
Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330

Query: 283  SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
             KL  +E AA           G+P +    +P     S++ S   SPR+  ++P+     
Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369

Query: 343  SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
                    R+ P   +P           R  PA   PA      PG   ++       R 
Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
                       P F  KP S +  E QT +F  +V G P PE  WF +G  +        
Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V ++ G+  L ++ A   DSG ++  A N  G+ S S  L VE +   +V P F   LK+
Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
              + EG    ++    G P P I WL N     P +Y +   E   G A L I   + +D
Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578

Query: 578  HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
               YT  A N  G+    C   V V   +   + + ++P          AP         
Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638

Query: 618  -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
                          K   P F + L+ L++          +++  G+P   V WLH+G  
Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
            ++ +            SL     +  D+G  TC A N  G   T A L V++        
Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758

Query: 715  ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
                               H+G             +P  +  P  V    G++    C +
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
             G P P V+W  +G+ L + +  F V + + +  L +   + +  G+ ++  +N  G   
Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876

Query: 805  CQVSLMLQNSS--ARALPRGREP 825
             +V L +Q        L R  EP
Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899



 Score =  113 bits (282), Expect = 2e-24
 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             +K S RK E L     +   AP     +   +V  G      + V   P  EV W HNG 
Sbjct: 26048 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26107

Query: 662   EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
             E+QES                 D H +  GT  ++C                        
Sbjct: 26108 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26167

Query: 683   ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
                      + VFPE T T              EA +S  EV++Q   T +      H  
Sbjct: 26168 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26227

Query: 719   TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
             +                              ++KPRS+T   G+S   SC   G+P PTV
Sbjct: 26228 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              WLR G+ L     H +V   +   T  +  VQ    G Y ++++N  G+   + +L +Q
Sbjct: 26288 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346

Query: 813   NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
              +                        + ++  R + P                 +++   
Sbjct: 26347 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26406

Query: 849   LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
             L    P +   +L+ E  +++          VL+ +  T     + +++    Q  +   
Sbjct: 26407 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466

Query: 901   LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
                ++    L+E D    + EI  E    + NLQ   +  K++ E+  K+   ++ D + 
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526

Query: 955   --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
               S + +K   K P P    P                          P+P    T D ++
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586

Query: 984   VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
             +  GGK KL  + G                            SS+  L  KA++ ++   
Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26646

Query: 1016  -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
              + Q +  + P   A   E +     A  +E +K M  AK  E L   + ASK    EE+
Sbjct: 26647 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26703

Query: 1068  KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
             KK     +     H   T   + SE   T    K     + + EG++L+L+  ++     
Sbjct: 26704 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26761

Query: 1128  TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
              + W LNG  L  ++       GS  +++I++A   D G+  C++K   G  +C   +T+
Sbjct: 26762 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821

Query: 1188  DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
                       + E+                SDA                 P  I  P  Q
Sbjct: 26822 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26838

Query: 1248  KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
              +  G++V    +++G       W K    I  S ++ +  S N   L I  A     G 
Sbjct: 26839 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26898

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+  +N  G   A  +L V+   + P+          +SL  S+   S    ++ Q  S
Sbjct: 26899 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26958

Query: 1368  IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
                + S++ +   +   +  S + Q +    E    + + +  G S  +Q     S++  
Sbjct: 26959 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 27016

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEV 1447
              G +   PK E   SD    E +V
Sbjct: 27017 AGIRGIPPKIEALPSDISIDEGKV 27040



 Score =  112 bits (279), Expect = 4e-24
 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
            +N  I EG    F  ++ GYP P++ W+++G+ I  G R+ +D    G  SL I  V  E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311

Query: 100  DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
            D G YT  A+N  G    + +L VE   A  LG P    TL      R  +P   +R  I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369

Query: 156  WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
                                                     P F  K       EGQ  R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429

Query: 180  FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
            F  K+ GRP P+  W   G   +       V +++G Q L I      D G +T +  N 
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489

Query: 239  SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
            +G++S+S  L+++ ++      FV + K  N          I + S+L+    A  + N 
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538

Query: 298  SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
                      W  NS    P    + ++E  K        + V Q               
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592

Query: 340  -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
              T   + ++    +PEP      ++ P G  R K  A P   P      Q      D+ 
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
             K   ++           P F+ K  S  +K      F C ++  G P   V W  +G P
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698

Query: 454  VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
            +      + +  + G   L    A +RDSG  +C A+N  G    S TL           
Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757

Query: 503  -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
                       ++E L  M    + + V  D                 V+EG+    +C 
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817

Query: 537  VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
            V G P P++ W LNGQ I+ ++       G+  L I D    D G     AEN  G +  
Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877

Query: 595  SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               + + +++  R    +L  AP  +P   +   G    +V    +   T +       E
Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929

Query: 654  VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
            V+ L     I      +ESE+    F++R  +            S    E + E      
Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
             E  +   E+  +    + E    T P F                  + +S T   G   
Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049

Query: 739  LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
                 + G P P   W ++G  + +    +     ++V  LV++ V    +    +   N
Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109

Query: 799  RVGECSCQVSLMLQ 812
              GE S    L++Q
Sbjct: 2110 IAGETSSHAFLLVQ 2123



 Score =  111 bits (278), Expect = 6e-24
 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +PP+I+  PE   ++AG+ + +   V G    TC W K   ++  S H+ V  +++ S L
Sbjct: 12593 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12651

Query: 1296  TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
              I    ++  G Y+L  EN  G+   ++ + V+D P PP      SDI + + +LSW+  
Sbjct: 12652 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12711

Query: 1356  SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
               DGGS + +Y +E  D +   W   LA+   TS  V  L+P  EY FRVRA N +G SE
Sbjct: 12712 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12771

Query: 1415  PSQESELTTVGE--KPEEPKD 1433
             P    ++        P EPK+
Sbjct: 12772 PLTSPKMVAQFPFGVPSEPKN 12792



 Score =  110 bits (275), Expect = 1e-23
 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)

Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
           AP+F+  L+   V+EG     +  + G PVP ++W  +GQ I  +     + +   G A+
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
           L I      + G Y+  A N  GQ + +A + V       K+E     AP     P F+Q
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108

Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
            L  + V  GSQV + V+V+G P P V +  +G EIQ S DF   Q G  +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168

Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
           ED+GTY+  A NS G   + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194



 Score =  109 bits (272), Expect = 3e-23
 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)

Query: 30  TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
           T+AP F  P +++ + EG+TA FE  + G+P P+V+W R+GQ I++        G++ +F
Sbjct: 3   TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58

Query: 90  S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
           S     L I AV + + G+Y+ +ATNGSG    T EL V+   A                
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102

Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
                          PP F  +L  + V++G   R   ++TG P P V + +    +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147

Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
               +S++  +  L I     +D G Y+    N  G+A+ +AEL +QG            
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207

Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
           + +A  S  R+T+     +   +  ++ + E  +D   AA +     +P R   PP   +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263

Query: 312 SQPQPP 317
             P PP
Sbjct: 264 RSPTPP 269



 Score =  109 bits (272), Expect = 3e-23
 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)

Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
            V+AG  +EL   VTG      TW K    +++ + + +EN    S +TI+ +++   G Y
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7456

Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             +   N  G   A V + V+DKP PPA     +D+ + S  L+W     DGGS + +Y +
Sbjct: 7457 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7515

Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
            E   + ++ W +L +T + T+F    L+P+ EY FRV A N+YG  EP Q S +T   + 
Sbjct: 7516 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7575

Query: 1427 KPEEPKDEVEVSD 1439
             P  P   +E SD
Sbjct: 7576 DPPGPPTRLEPSD 7588



 Score =  105 bits (262), Expect = 4e-22
 Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%)

Query: 415  KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            +F    +  +V E +   F CEVS  P   V W  +   ++  +  I++ ++   H L +
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
               R  D+G Y+  A            +   +L V        S+ K+  VIE Q  V++
Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121

Query: 535  CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
              V    V    W  +G  I +      +   E  +  + I +    D G YT +A    
Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
                            +R S  L   AP  P     LQ L  + V  G        +SG 
Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P P++ W      +       F   G +++L + E FPED   YTCEA N  G   T A 
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 710  LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            L+V+ P     D   P +    I+  +    S GQ     C ++G       + +D K  
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337

Query: 762  CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             K +  F + Q ED + L + +  P   G Y  +  N VG+ S   +L L+
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388



 Score =  104 bits (259), Expect = 9e-22
 Identities = 102/419 (24%), Positives = 172/419 (41%), Gaps = 48/419 (11%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+   + Q   V+  +  +F   +SG P+P+++W+ E   +       +   D   + L 
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
            L++A   D+  Y+C A N  G  + S +L VE   V+          P+  + L+D    
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311

Query: 527  EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
            EGQ    QC V GT + +++W    +   P ++ R T      +L I +A PED GTYT 
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 584  LAENALGQVSCSAWVTVHEK--------KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
            +A NA+GQVS +A +++  +        K  R+S     VA S  T         ++K  
Sbjct: 3371 VASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIKSF 3430

Query: 636  DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 695
             GS     VQV  +     I  H    +Q+++          H+  + ++      +  C
Sbjct: 3431 QGSSYEYEVQVFESVSQSSI--HTAASVQDTQ--------LCHTASLSQIAESTELSKEC 3480

Query: 696  EAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL 755
             A  S GE                 P      + VT   G +    C +  D F  V W 
Sbjct: 3481 -AKESTGEA----------------PKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWT 3523

Query: 756  RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
             +G A  +++   +  QN ++  L +  VQ    G Y  ++ N  GE +    L ++ +
Sbjct: 3524 HEG-AKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGA 3581



 Score =  102 bits (253), Expect = 5e-21
 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             +++ E  K RAG SV+L   ++G    T  W K  K++Q +  + VEN+ + + + I  A
Sbjct: 20571 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20630

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              + + GCY L + N +GS  A + + ++DKP PP G      + +  +TL W   + DGG
Sbjct: 20631 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20690

Query: 1361  SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             + +  Y +E  +++   W    + L  C  T+  +   +  +EY FRVRA+N YG  EP 
Sbjct: 20691 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20747

Query: 1417  QESEL 1421
             +   +
Sbjct: 20748 ESDSV 20752



 Score =  101 bits (252), Expect = 6e-21
 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)

Query: 1236  MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
             +PP +   ++  E   V+AG +V     + G    T  W     +I+  EH  VE     
Sbjct: 11201 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11260

Query: 1293  SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
             S LTI    +   G Y + V N  GS+   V+LTV+D P PP G     D+    +T+SW
Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11320

Query: 1353  YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
                  DGGS V +Y +E  D+   TW  +++  S T   +  L    EY FRVRA N  G
Sbjct: 11321 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11380

Query: 1412  TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
                P  +S  T    K  P  P  +  V+D  E    V +     +    ++ +Y +E R
Sbjct: 11381 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11438

Query: 1470  LGSGKFGQV 1478
               +GK+ +V
Sbjct: 11439 EVTGKWVRV 11447



 Score =  101 bits (252), Expect = 6e-21
 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+ +M P+   + +   V AGES ++   + G    T  W+K  +++  +  +++++++
Sbjct: 16235 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16291

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L++  A +   G Y L  +N  G R   VN+ V+D+P PP G    S + +   TL
Sbjct: 16292 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16351

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGGS + +Y +E  +++   W  + A  ++ S  V  LL  +EY FR+ A+N 
Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16411

Query: 1410  YGTSEPSQESELTTVGE--KPEEPK 1432
             YG  EP +   +        P+ PK
Sbjct: 16412 YGVGEPLESEPVVAKNPFVVPDAPK 16436



 Score =  101 bits (251), Expect = 8e-21
 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)

Query: 1243  FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
             F +   VRAG S+ LF    G    T  W K    +  S    +  +++ S LT+    +
Sbjct: 22058 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22115

Query: 1303  EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
                G YTL VEN  GS+     + V+D P PP G     D+   S TL W     DGG+ 
Sbjct: 22116 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22174

Query: 1363  VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             +  Y +E  +++ ++W+ ++  C    F V DL     Y FRV A+N YG  EP +  E 
Sbjct: 22175 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22234

Query: 1422  TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
                 E+P  P+  D V+ S         +P+ D         +   QK SDF+ +E    
Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22293

Query: 1472  SGKFGQVFRLVEK 1484
                   V RLVEK
Sbjct: 22294 KQLTFTVERLVEK 22306



 Score =  100 bits (250), Expect = 1e-20
 Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%)

Query: 63   QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
            +V W+   + + S  +F  L D   + T++LVI  V+ ED +G+Y CEA N SG    + 
Sbjct: 4463 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4519

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
            +LTV    A     PV+ +                           K+  + V  G + +
Sbjct: 4520 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4547

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F+C+I   P  +  W K    +  S + S+     +  LEI      D G YTC   N  
Sbjct: 4548 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4607

Query: 240  GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
            G  S +A L  ++ G +   R  + E K    + ++EV   +V+ K  + +  +   K  
Sbjct: 4608 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4664

Query: 295  KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
            +    P     PP      P+P  E ++ +     R  P+   + +   +I L A   +P
Sbjct: 4665 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4718

Query: 355  EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
            +P A    +  P  E    P    P T P       ++    +AA  + P++G       
Sbjct: 4719 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4777

Query: 415  KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441
              E+     +P S   K      F  ++  +P                            
Sbjct: 4778 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4837

Query: 442  KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
             P  A   W  +G+ + R+        D     L ++  +  D+G Y+C       + + 
Sbjct: 4838 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4896

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
            +  L VE L V  V     ++ ++  V++GQ   L C +       + W  +G+ +    
Sbjct: 4897 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4950

Query: 559  STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
                 GV      L I DA   D GTYT   ENA   + CS+ V V E
Sbjct: 4951 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4997



 Score =  100 bits (250), Expect = 1e-20
 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             ++F +   ++AGE+  L   V+G  P T  W K  K+++ +  ++++ ++  + L    +
Sbjct: 15160 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15219

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              +   G YTL   N  G  +   N+ V+D+P PP G    +++ S    LSW+    DGG
Sbjct: 15220 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15279

Query: 1361  SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             + +  Y ++  +++   W  +A+  + T   V  LL  +EY FRV A+N YG  EP +  
Sbjct: 15280 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15339

Query: 1420  ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
              +  V     P+ PK+ EV     D        P+ D  +  IN        Y +E R  
Sbjct: 15340 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15389

Query: 1472  SGKFGQVFRLVEKKT 1486
               K GQ +    KKT
Sbjct: 15390 -DKAGQRWIKCNKKT 15403



 Score =  100 bits (249), Expect = 1e-20
 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V AGE +++     G      TW K    ++++  +  E++EN S LTI  A +E  G Y
Sbjct: 15854 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15913

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + + N  G     +N+ V+DKP PP G     ++ + S+TLSW    YDGGS++ +Y +
Sbjct: 15914 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15973

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             E  D++  TW+ + AT   T+     L    EY+FR+ A N YG S
Sbjct: 15974 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 16019



 Score =  100 bits (248), Expect = 2e-20
 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)

Query: 512  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
            V   F S +K+  ++EG      C + G P+P+I W  +G+ I    +Y     + G A 
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
            L I   LPED G YT  A N  G   CS  + V          Y   L PV+  +  +P 
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362

Query: 624  -------------------------------------------------IFLQGLSDLKV 634
                                                             +F+      K 
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            ++G      ++V G P PE  W H+G +I    +     ++ GTQ SL I    P D+G 
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            +T  A N AG      +LTV+      +P F+ K ++V    G  + +     G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541

Query: 753  HWLRD 757
             WL++
Sbjct: 1542 VWLKN 1546



 Score =  100 bits (248), Expect = 2e-20
 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+V   A++  S  +L     +V  +PL     FI P  ++ + E   AKFE  V   P+
Sbjct: 5513 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5563

Query: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
                W +  Q IT   RF L+  G + +  +   A  +E +  +  E  + SG       
Sbjct: 5564 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5622

Query: 115  --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
                    + VT +      F  +L    +                       KT    F
Sbjct: 5623 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5682

Query: 145  SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
               +++    I  E                P F  KL      E       C+I+    P
Sbjct: 5683 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5742

Query: 191  QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
             V W K    ++PS    +      ++L +    + D+G YTC    G+ K S   ++  
Sbjct: 5743 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5799

Query: 249  ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
                      S++ +++    F  ET+ +  D+            +     I +E K+ S
Sbjct: 5800 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5857

Query: 288  LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
            L       NC   Q GG    AAN +       K      L   KD   TA +T      
Sbjct: 5858 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5913

Query: 342  SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
             S         L+  +++P  +      + P  E +      R      +    G   + 
Sbjct: 5914 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5963

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
            +K       +  +      +F    + Q V+E  T    CEVS     +V WF  GT + 
Sbjct: 5964 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 6020

Query: 456  RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
            + +   E+  D     L +      D  TY+C A + +   SC+       L V+     
Sbjct: 6021 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 6070

Query: 516  FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
            F   L D  V E +    +C +      ++ W  +G  I+  +      +  V  L I  
Sbjct: 6071 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6129

Query: 573  ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
             L +D   Y+C    A      S  +TV E+++                  +F + L+++
Sbjct: 6130 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 6167

Query: 633  KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            +V +   + +  +VS  P  EVIW     EI E+  +     G +  L IQ    ED G 
Sbjct: 6168 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6226

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            Y C   +S    RT   + V E        FISKP+++    G+     C+I+ + FP V
Sbjct: 6227 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6277

Query: 753  HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
             W RD K L +    ++V+ +     LV+K       G Y +++
Sbjct: 6278 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6320



 Score =  100 bits (248), Expect = 2e-20
 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
             MPP I    E  +V  G +V +  K+ G    T TW K        ++ +    H+    
Sbjct: 9811  MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9869

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
              ++   L I  +R+   G YT+   N LG+   ++ L V+ +P PP G      + +  +
Sbjct: 9870  VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9929

Query: 1349  TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
             TLSW+    DGGS + +Y IE  ++  KTW  +++  +  ++ +  LL  HEY FR+ A 
Sbjct: 9930  TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9989

Query: 1408  NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             N YG  EP        +  +PE  ++   V  + D      V   ++T+N E+   D
Sbjct: 9990  NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 10038



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)

Query: 289  EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
            E  + +K    PQR  S P       +P     P E+ +++             ++KT+ 
Sbjct: 693  ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750

Query: 344  SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
              T +   V   PR       SP     K   P             G +  ++ +A   +
Sbjct: 751  LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796

Query: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
              E    S+  K     ++  VK ++T   R      P P+   F +     + E  +EV
Sbjct: 797  QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852

Query: 464  YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
             ++ G   + +     R+          A+   +      VE   +    P+  S LK+ 
Sbjct: 853  KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
             VIEG+   L+C + G P P +TW      I+ +   + T ++G+A L I++A  ED G 
Sbjct: 907  TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966

Query: 581  YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
            +TC A N  G VS S ++ V      EK+++  +E                         
Sbjct: 967  FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026

Query: 615  -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
               P +P AP F+      K+++G  V    QV GNP P V W  +G  +     +   +
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             ++  +  L I   F +D G YT    N  GE    A L  +  ++
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P+ +M P+   F +   V AGE+  L   V G    T  W++  K+I+ES   +++N++ 
Sbjct: 17318 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17374

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
              + L +  A +   G Y L   N  GS+   VN+ V+D+P PP G    + + S   +L+
Sbjct: 17375 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17434

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
             W     DGGS +  Y +E  +++   W  +A+   + S  V  LL  +EY FR+ A+N Y
Sbjct: 17435 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17494

Query: 1411  GTSEPSQES 1419
             G  EP + +
Sbjct: 17495 GVGEPLESA 17503



 Score = 97.8 bits (242), Expect = 9e-20
 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)

Query: 426   KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +E   VK+ C++    +  +V W+     +   E     YED G   L +      D GT
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25333

Query: 485   YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
             Y C   N  G+ S                 C  T++      + + ++E  P F+  L +
Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25393

Query: 523   CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
                  G++     ++   P P +TW  +GQ I+   +        + G+ +L I     +
Sbjct: 25394 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25453

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
             D   YT +A N  G+ SC A +TV           L P        P+F + L++ +  +
Sbjct: 25454 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25503

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
             G  V   ++VSG PPP + W  +G  +    +      G   ++L I++  PEDTG Y  
Sbjct: 25504 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25563

Query: 696   EAWNSAGEVRTQAVLTVQ 713
              A N+AG    QA L V+
Sbjct: 25564 TATNTAGSTSCQAHLQVE 25581



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G +V L     G    + +W+K    ++ESE ++   +EN   L+I  A++EH G Y
Sbjct: 21270 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21329

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T++++N +      + +  +  P  P G     +I++ S+ LSW     +GG  +  YSI
Sbjct: 21330 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21389

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  +++   WK + ++   T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21390 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21437



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)

Query: 161   PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
             P+   ++    V  GQ  RF   +  +P  +V W    V LQ S+++  +  +G+  LEI
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26128

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
                + DD G Y  +  N  G+AS  A L + G D    +  R  +     V  E+T    
Sbjct: 26129 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26188

Query: 279   --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
               +S   K   +EA++  +   S     +    + S  +    ++++S     ++  +  
Sbjct: 26189 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26245

Query: 337   VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
               +K  +++   AAR+  +PR+    +    GE  +          PT    L    V+S
Sbjct: 26246 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26297

Query: 397   KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
              +A  ++     + +   +  S   S E     V EN   K   E +  I K  V     
Sbjct: 26298 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26355

Query: 451   GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
              +P R +     V           +K+  R  S   S   + +  +   + T +V+ L V
Sbjct: 26356 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
                 P  +  LK  A    +   L C V  + +    +TW  +G+ ++    +       
Sbjct: 26410 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466

Query: 564   GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
             G  EL I +    D G Y C      G      Q    A+ ++HEK        KS +K+
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526

Query: 610   EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
                     ++P AP       + + GL D  V   S     V+ +G P P  IW  +G  
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586

Query: 663   IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             I +   +   +      L I +    D+G YTC   NSAG V +   LT++   D
Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26641



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG +V L   V G    T +W K    ++ +E +K+    N   L + +  ++  G Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN  GS+ A + L V+DKP PPA     + + S    LSW     DGGS + +Y +
Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13120

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             +  +++   W ++ AT   TS +V+ L+  HEY+FR+ A N YG  +P
Sbjct: 13121 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13168



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)

Query: 5     KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
             K +    I+KTS + +  R  +    E  AF      + I EG     +  + G  +  V
Sbjct: 26713 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26763

Query: 65    TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              W  NG  +T+   +    G+ G+  +L I      D G  TC +    G  +   +LT+
Sbjct: 26764 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821

Query: 124   EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
                          SK L D   APA  ++P                  + EGQ   F+C+
Sbjct: 26822 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26851

Query: 184   ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
             I+G P P++ W K N+P+  S+ VS+S    +  LEI   +  D G YT    N  G+ S
Sbjct: 26852 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26911

Query: 244   MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
              +A L +  L                 V +    V+ + S   SL+   +++S   S+ +
Sbjct: 26912 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26954

Query: 302   RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
             +  S    ++S      E K  S      ++ Q   ++ +SSS                +
Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26999

Query: 362   GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
             G+ + +  E                    S   + KA  R IP         PK E+ P 
Sbjct: 27000 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 27031

Query: 422   SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
                + E + +   C  +G P PEV W   G  +  QE G   +        L ++  + +
Sbjct: 27032 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 27091

Query: 481   DSGTYSCTASNAQGQLSCSWTLQVERL 507
             D G Y+ +  N  G  S +  + +  +
Sbjct: 27092 DGGLYTLSLGNEFGSDSATVNIHIRSI 27118



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)

Query: 1228  PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P T      PP + + F +   +R GE+  L G+ +G      +W K    + E +   +
Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
             + +     L  + A++   G Y ++VEN  GSR+    + VVD+P PP G     ++   
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
              + +SW     DGGS + +Y IE  +     W  + +  + T+  V  LL   +Y FR+ 
Sbjct: 10623 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682

Query: 1406  AINVYGTSEPSQESELTT-----VGEKPEEP 1431
             A N+YG S+P     +       V + P++P
Sbjct: 10683 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10713



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            +G    + + +    K P      P I     D  V  GE + +          T +W K
Sbjct: 8061 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
              K+++ S+ + ++N    + L +  + +   G YT+ +ENKLGS  A +N+ V+  P P
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8177

Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
                  ASDI  SS  L+W    +DGG+ +  Y +E  ++  +T+  + +  +  S+ V+
Sbjct: 8178 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8236

Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
            DL+P+ EY FRV+A+N  G  E   E +   + + P++P D   +VEV +   +   + +
Sbjct: 8237 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8295

Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
            +    +   K+  +  I E++  G+
Sbjct: 8296 KPPLYDGGSKIMGY--IIEKIAKGE 8318



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)

Query: 506   RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
             ++A +E+ P    ++      EG      C +       ++TW    + ++ +     T 
Sbjct: 25256 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25314

Query: 562   EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
             E GVA L+++D    D GTY C   N  G+ S  A + V               KK  R+
Sbjct: 25315 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25374

Query: 609   SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
             ++ + L   P + T P++     +     G  V   V ++ +P P V W  +G +I+  +
Sbjct: 25375 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25429

Query: 668   D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
             +   + FE     + L I  V  +D   YT  A N  GE   +A LTV     P D T +
Sbjct: 25430 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25489

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
             P F     +     GQSV     ++G P PT+ W +DG+ L        + +  D + L 
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549

Query: 781   LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             ++   P   G Y +   N  G  SCQ  L ++
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581



 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)

Query: 1249  VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             ++AG+++ L    + G      +W K  K I+ S+  ++ ++   S LTI  A ++  G 
Sbjct: 14085 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14144

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+   N  G++   V +TV+D P PP G    S++ +   TL+W     DGGS ++SY 
Sbjct: 14145 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14203

Query: 1368  IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E  +++   W    +++ +CR  +     L+  +EY FRV A+N YG  EP Q   +  
Sbjct: 14204 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14260

Query: 1424  VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             V    P  P ++ EVS+       V   T T++ ++ V D
Sbjct: 14261 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14293



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S+ +F  + G      TW K    I       +EN+E+ + L I    +   G +
Sbjct: 14483 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14540

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + +EN  G +   VN+ V+D P P       +DI   S+TL W     DGGS + +Y +
Sbjct: 14541 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14599

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++    T C   ++ V  L    EY FRV A N YG  EP++ +E     E 
Sbjct: 14600 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14659

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
             P  P D + + D  +    + +     +   K++ +    +R GS ++  +
Sbjct: 14660 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14709



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+  M    ++F +   V+AGE +++   + G      +W K   +I+E    ++ +++
Sbjct: 19481 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19537

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
             N + LT+    +   G Y L ++N  G+R   VN  V+DKP PPAG    + + +   +L
Sbjct: 19538 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19597

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             SW     DGG+ +  Y +E  ++++  W       + TS  V  LL  +EY FRV  +N 
Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19657

Query: 1410  YGTSEP 1415
             YG  EP
Sbjct: 19658 YGVGEP 19663



 Score = 94.4 bits (233), Expect = 9e-19
 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ L   V+G  P   TW K  + I  +    ++ +E+ S L +    +   G Y
Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23210

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN+ G + A V + V D P P        ++   S+T++W   + DGG+ V +Y +
Sbjct: 23211 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23269

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++A + +K + T C  T + +  L+    Y FRV   N+YG  EP + S+   V E 
Sbjct: 23270 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23329

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             P  P  ++EV D       V   TVT+  E+ + D
Sbjct: 23330 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23356



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+A E +++     G    T  W K  + ++E+  + V +S+  + L+I  A +E  G Y
Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19160

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L V N  GS    + + V+D+P PP G     ++   S+T+SW    YDGG  + +Y +
Sbjct: 19161 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19219

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++ + TW  ++     TS  +  L    EY+FRV A N YG S  S+ S    V E 
Sbjct: 19220 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19277

Query: 1428  PEEP 1431
             P  P
Sbjct: 19278 PFSP 19281



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
            +AG  + +   + G      +W    K +K +++  H      ++E +EN S + I   +
Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            + H G Y++  +NK G + A   + V+D P PP      SDI   S  LSW     DGG 
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9636

Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             ++ Y IE      K W ++   C ST+F V DLL + +Y FRVRA N +G   P +  +
Sbjct: 9637 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9696

Query: 1421 LTTVGEK--PEEPKDEVEV 1437
             TT  +   P +P  ++++
Sbjct: 9697 RTTARDPIYPPDPPIKLKI 9715



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            + P F     +L +K    A FE R+   G P   V W  +G+P+ +  R  +     G 
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
             SL     +  D G  TC ATN  G    +  L V  E S  ++   P   K L      
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773

Query: 147  PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
              +    ++ G       +  P        V V EG+  RF C++TG PQP+V W     
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             ++ S R  V   +G+  L+I      D G       N  G      +L IQ  +   RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891

Query: 260  FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
             +R       +        +  E  K+D      ++K     +R          +     
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951

Query: 319  ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
             SK +   +       T V  K+          ++             + EE+K  A   
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              T PT +P              +I +    ++  PK   + QSQ V +     FR  V 
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
            G P PE  W+  G  + R +     + +     L +      DS +    A N  G+ S 
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
               L V+   ++    +F+  L+D    E             P  ++ W  +G  +    
Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172

Query: 558  --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
              R   +  V  L I      D   Y+C              V V ++     ++ ++  
Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218

Query: 616  APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
            A  +     F++ L D++V +     +   VS    PE I   W HN  E++ +  +   
Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269

Query: 673  QRGTQHSLCIQEVFPEDTGTYT 694
             R  + +L +++V  ED G Y+
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
             P A++ P+   + +   V AGE+  L   + G       W K  K+++E+   M+++++ 
Sbjct: 18400 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18456

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L +    +   G Y L + N  G++   + + V+D+P PP G    + + +    L
Sbjct: 18457 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18516

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y IE  +++  +W +++T  ++ ++ V  LLP +EY FRV A+N 
Sbjct: 18517 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18576

Query: 1410  YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
             YG  EP +   +T     KP  P    EVS
Sbjct: 18577 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18606



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
             T +  TV+      T   + MP + I  P      AG  VEL   + G  P   +W    
Sbjct: 23418 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23471

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
              +++ESE + VE     +KLTI        G YTL ++N  G+    + + ++DKP PP 
Sbjct: 23472 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23531

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
             G     +I ++S+T+SW     DGG+ +  Y +E  D+    W  ++ +   ++F    L
Sbjct: 23532 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23591

Query: 1395  LPDHEYKFRVRAINVYG 1411
                +EY FRV A N +G
Sbjct: 23592 TEGNEYVFRVAATNRFG 23608



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            +P+T  P  +   +N+ + EG +   E  + GYP P VTW+R    I S   F +     
Sbjct: 892  IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
            G   L+I     ED G++TC A N +G    +  L V+ S   +     V++   T   R
Sbjct: 950  GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009

Query: 144  F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
            F  S   V T  S+  E         P F TK     + EG    F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069

Query: 195  LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             K  VPL    R  VS +++ G   L I     DD G YT +V N  G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AGE V++     G  P T TW K  K +       +EN+++ S LTI    +   G Y 
Sbjct: 20979 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 21038

Query: 1310  LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             L +EN +G  + + V++ V+D P           +   ++TL W     DGGS + +Y I
Sbjct: 21039 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  D+  +TW  ++  C STSF + DL     + FRV A N  G  EP + +E     E 
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21157

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
             P  P  ++ + D  +    + +     +    ++++  + ER G G+
Sbjct: 21158 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21201



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+ G+ +++   ++G    T TW K    ++++  + V +S + + L+I    ++  G Y
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + V N +G + A + +  +DKPDPP G     D+ + S+TLSW    Y GG  + +Y +
Sbjct: 16996 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 17055

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             +  D+    W  + AT   T+  V  L    EY+FR+ A N YG S
Sbjct: 17056 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)

Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
            KV+AGE V +   VTG       W K    I++          +V  SE  ++L+I  A 
Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            +E  G YT+   N+LGS    V++ V D+P PP      +DI++ S  L+W     +GGS
Sbjct: 9164 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9222

Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
             +  Y I+  D++ K   W+E+  T     + +  L+P+ +Y+FRVRA+N YG S+  + 
Sbjct: 9223 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9282

Query: 1419 SEL 1421
             ++
Sbjct: 9283 DKV 9285



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)

Query: 1226  PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
             P P        PP++I       +Q ++ G+++ L   + G      TW K  +      
Sbjct: 10899 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10958

Query: 1283  HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
              + V  +  GSKL I  A  E  G Y+L VEN  GS+   V + V+DKP PP      S+
Sbjct: 10959 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 11015

Query: 1343  IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
             IR  S  L+W     DGGS + +Y +E  D A+  W  L AT +  S   + L   ++Y 
Sbjct: 11016 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11075

Query: 1402  FRVRAINVYG 1411
             FRV A N YG
Sbjct: 11076 FRVAAENQYG 11085



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)

Query: 1232  PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
             PKA    +PP+I    + +KV   RA  ++ LF  + G       W   R   +  +   
Sbjct: 15544 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15601

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             +E++ + + L +    +   G Y L VEN  GS+ A VN+ V+D P PP       ++  
Sbjct: 15602 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15660

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S+TL+W     DGGS +++Y +E  +S  K +  +AT C  TS+ V  L     Y FRV
Sbjct: 15661 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15720

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A N YG   P++ +E     E+P  P
Sbjct: 15721 LAENEYGIGLPAETAESVKASERPLPP 15747



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)

Query: 1249  VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             V AG  + +   V+G  P T TW M  R   QE+    +E +   S + I   ++ H G 
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10287

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
             Y+LL +N+ G R+  + + V+D P  P GTP  A ++ + S  L+W+    DGGS + +Y
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10346

Query: 1367  SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
              IE  +S  + W  +  T    +  VQ L+    Y FR+ A N  G     + SE   + 
Sbjct: 10347 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10406

Query: 1426  EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
             E    PE P+D +EV        EV   TVT+       D       Y +E RL G+ KF
Sbjct: 10407 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10458

Query: 1476  GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
                     K T      + +     KE +     +S +N +   K   C
Sbjct: 10459 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10500



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ LF  + G       W K   +I+++  + V +S   + L +    +   G Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16706

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL +EN  G++ A V + V+D P PP      ++I   S++++W     DGGS +++Y +
Sbjct: 16707 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16765

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++  + T C   S+ +  L     Y FRV A N YG   P+Q ++   V E 
Sbjct: 16766 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16825

Query: 1428  PEEP 1431
             P+ P
Sbjct: 16826 PQPP 16829



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)

Query: 1228  PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
             P   P      +++++P+   D++ + G  V   G +  T PI       C W K  + I
Sbjct: 23813 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23872

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
               S+   +  SE  ++L I  A +   G Y L++ENK G +   + + V+  P+ P G  
Sbjct: 23873 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23930

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
                DI+  S+ +SW   + DGG+ +  Y +E  +     W  + +  R TS  V+ L  +
Sbjct: 23931 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23990

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
              EY FRV A N +G S+P +  E  T       PE P +  EV D  +    + +     
Sbjct: 23991 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 24050

Query: 1455  NTEQKVSDFY 1464
             +   +V+ +Y
Sbjct: 24051 DGGSRVTGYY 24060



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)

Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
           AP F Q L  + V++GS  T    +SG P PEV W  +G  I  S            +  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
           L I  V   ++G Y+ +A N +G+  + A L V+   +   P F+ + +S+T   G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122

Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
           +   + G P P V + RDG  + + +  F++ Q  D+++L++ +  P  +G Y +   N 
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 800 VGECSCQVSLMLQ 812
           VG  +    L++Q
Sbjct: 182 VGRATSTAELLVQ 194



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)

Query: 408  QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
            Q++   P     P+   V E +T +FRC V+G P+P+V W+L G  +R+ +     Y+  
Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846

Query: 468  GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
            G HYL ++  ++ D+G    TA N +G +     L++++         F SVL+      
Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900

Query: 528  GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
             +  V     LQ  V+    P        +  L   + I + +   E+   EL  +    
Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958

Query: 576  EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
             + G Y  +              E  L +       W      E+K +   E  + +   
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018

Query: 619  KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            KP          AP   + +    V  GS     V+V G P PE  W  NG +I+ S+  
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078

Query: 670  H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
            + +        L I++V  ED+ +   +A N AGE  + A L VQ     T   F  + +
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135

Query: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
             V A    ++        +PF  V W +DG
Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)

Query: 1232  PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
             PK  + P  I      +    VRAG  + LF  V G      TW K      +++ +   
Sbjct: 12292 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12348

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             V+  +  + L I  + ++  G Y+L + N  G +   VN+ V+D P P +     SD+  
Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12407

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S  +SW     DGGS V  Y +E  ++  KTW  +    + TSF+V +L+P +EY FRV
Sbjct: 12408 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12467

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A+N YG   P+   +     +   EP
Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEP 12494



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)

Query: 1228  PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             P   P    P  I+  PE +          +RAG ++ L+  V G  P   TW K    +
Sbjct: 13370 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13429

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             ++   + +++++  + L      +   G Y L +EN  G ++  + + V+D P PP    
Sbjct: 13430 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13488

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
                +I   S  ++W     DGGS + +Y ++  D+  K+W  + T C  TSF V +L   
Sbjct: 13489 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13548

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
               Y FRV A N YG  +P +  +     + P
Sbjct: 13549 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13579



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)

Query: 1237  PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    + +KV   RA  ++ LF  + G       W K    +  ++  ++E + + +
Sbjct: 18799 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18856

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L I    +   G Y L +EN  GS+ A VN+ V+D P  P       +++  S+TLSW 
Sbjct: 18857 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18915

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DGG+ + +Y +E  ++  K +  +   C  T+F +++L     Y FRV A N YG 
Sbjct: 18916 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975

Query: 1413  SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
               P++ +E   V E P  P     V        +V   T TI  E+  SD
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 19017



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S  +     G      TW   R++ + ++ +++E   N ++L+I    +   G Y
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17788

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L +EN  GS+ A V + V+D P PP       ++R  S  L W     DGG+ V++Y I
Sbjct: 17789 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17847

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             +  +S  K +  +++ C  TSF V++L     Y FRV A N +G   P +  +     E 
Sbjct: 17848 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17907

Query: 1428  PEEP 1431
             P  P
Sbjct: 17908 PSPP 17911



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             ++AGE +++   V G      +W+K  + ++++  + VE +   + L I    ++  G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+   N  G+    +++ V++KP PP G     ++ +  + +SW   +Y GG  + +Y +
Sbjct: 18078 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18137

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  D+   TW  + AT   T+  +  L    EY+FR+ A N YG S P
Sbjct: 18138 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18185



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
           P F    QS  V E  T  F   +SG P PEV+WF +G  +       +++    G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
            +      +SG YS  A+N  GQ     T   E L   E A P+F   L+   V +G   
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121

Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
            LQ  V G P P + +  +G  IQ +   + + E  +  L I +A PED GTY+  A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
           +G+ + +A + V   E+  ++K++ ++  A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+L P +    EG TA+F+ +V G P P+  W  +GQ I +     +     GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            I      D G++T  A N +G   ++V LTVE                       AVE  
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
                 +  P F  KL  V +KEG       + TG P P + WLK +  + P    ++ + 
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               G   L+I      D   YT   +N +G+ +   +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)

Query: 1261  VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
             + G    + +W K    +     + VE+S   + L +   ++   G YT+ ++N  G+++
Sbjct: 13701 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
               +++ VV KP  P G     ++ + ++TL W     DGGS + +Y +E  DS N  W  
Sbjct: 13761 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13820

Query: 1381  LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
              A+  + T+F V  L    EY FRV A N YG  E
Sbjct: 13821 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13855



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)

Query: 1237  PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    FP     VRAG ++++   ++G      T  +    ++ +     E +    
Sbjct: 20168 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20227

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              + +  +     G Y +   N  G+ +A +N+ V+D+P PP G    SDI   S+TL W 
Sbjct: 20228 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20287

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                YDGGS V +Y +   +++   W E+ AT   T   V  L    EY+FR++A N +G 
Sbjct: 20288 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20347

Query: 1413  SE 1414
             S+
Sbjct: 20348 SD 20349



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)

Query: 1238  PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             P I++F  +      +++GES+ +   V G      TW K   +I++  +M++ +    +
Sbjct: 21650 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21709

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L +  A ++H G YT+  +N  GS +A++ + V D P    G    ++I    +TL W 
Sbjct: 21710 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21769

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DG + +  Y IE  +++   W  +   C + S+    L+  +EY+FRV A+N +G 
Sbjct: 21770 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21829

Query: 1413  SEP 1415
               P
Sbjct: 21830 GRP 21832



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)

Query: 882  HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
            H EE+  QQ   +  +++    ++S   ++E   +  PA +      + + VKP+ +   
Sbjct: 676  HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726

Query: 939  SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
            SE   K    + +   S + K     T     V   P+ A+P F      K  +P     
Sbjct: 727  SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783

Query: 998  SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
              A    +      K LS    +   + +  +  A T+KP      AE   L     A  
Sbjct: 784  YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840

Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
             +  KS +  E+KK+V   +       GTT  E+R E                       
Sbjct: 841  PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            T P     L++V V EG+ + L+C +S  P  T+ W      ++++    ++ +  +  +
Sbjct: 895  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
             I +A  ED G + C A N+AG    SC   V V +    E T   E  +   K  +   
Sbjct: 955  MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                +D ++ ++ A    P A   P  I  P  QK+  G SV    +V G       W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071

Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
                +      KV  N + G  KL I     +  G YT++V NK G   A  +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)

Query: 405  MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
            ++G++ +   K + +P         Q+V E   V+   +VS +   E  W  +G  V+  
Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352

Query: 458  EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
            +  + +  D  SH L +      D+G YS T       L  S + +V   +V  + P   
Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
              LKD  VIEG   VL+C V    V  + W LN + I+     ++  +     L I    
Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462

Query: 575  PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
              D G Y  +    +G+V  +  ++V + K                     ++GL DL  
Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
             +   V   V++S +   +V+W     EI+ S  +  E  G  + L +  +  +D G YT
Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
                  AGE  T   LTV           ISKP    T +  Q  +  C +A +P     
Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605

Query: 754  WLRDGKAL 761
            WLRDGK L
Sbjct: 2606 WLRDGKHL 2613



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)

Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
            D E R++ +   AP  K   QD+ V  GK L +     + P A   W    + L T    
Sbjct: 6682 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6741

Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
              +++ S   +  +K    D+G YK V +N  G+AE    + V D P             
Sbjct: 6742 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6786

Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
                   PV   E   T   +               +    ++ +  G S ++ G V   
Sbjct: 6787 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6823

Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
            + I   TW+    + +  E       + G +     + +   G    +  +N + +R   
Sbjct: 6824 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6883

Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
                  D P PP      +D+    ++L+W    YDGG+ + +Y IE+ D  +  W    
Sbjct: 6884 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6936

Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            T R+   S  V D++   EY FRVRA N  G  +PS  +    V +  E P   V ++  
Sbjct: 6937 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6996

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
            D+ +  V  +      +        I ER   GK   +    +LV + T KV       K
Sbjct: 6997 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 7056

Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
            +    SA+ K  +     I+  L
Sbjct: 7057 YLYRVSAENKAGVSDPSEILGPL 7079



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG S  +     G       W K    ++   +  V+ +++ + LTI  A +   G Y
Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19950

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL ++N L +    + + V+D P PP       D+   S  LSW     DGG+ V++Y I
Sbjct: 19951 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 20009

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  +++ K W  +   C   S+ V +L     Y FRV   N +G   P++  E   + EK
Sbjct: 20010 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20069

Query: 1428  PEEPK 1432
             P  P+
Sbjct: 20070 PSPPE 20074



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             E + S  SE + P +     AP F + L +L V   S  T+  +V+G+P P V W   G 
Sbjct: 24602 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24661

Query: 662   EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
             EI  +   +  ++ +G  H L I  V  +D   Y   A N  G V   A L V+ P    
Sbjct: 24662 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24721

Query: 720   QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
              P  +    +V A  G+ V I    +G P P + W + G+ L  + GH++V+      +L
Sbjct: 24722 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24780

Query: 780   VLKK-VQPWHAGQYEILLKNRVG 801
             V    V+   AG Y +  KNR G
Sbjct: 24781 VFPNGVERKDAGFYVVCAKNRFG 24803



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)

Query: 23    RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
             R D+M L E P  F LP  N     G   +F   +  +PEP VTW+++GQ I  G    +
Sbjct: 25374 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25433

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
             +  +   +G + L I++V  +D  +YT  A N  G      +LTV       L  P    
Sbjct: 25434 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25486

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             TL                    P F   L     +EGQ   F  +++G P P + W K  
Sbjct: 25487 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527

Query: 199   VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
              PL     +  + E      L I     +D G Y     N +G  S  A L ++ L    
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587

Query: 258   RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
             + F +  +     V+K++   +     L   E+
Sbjct: 25588 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25619



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
             V+AG+++ L   V G       W K +    +  S  +K++   + SK ++  A++   G
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11967

Query: 1307  CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
              Y +   N  GS  A   + V+DKP P        D+ S   T+ W     DGG  +Q+Y
Sbjct: 11968 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 12026

Query: 1367  SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
              +E  ++    W    AT  +    V  L+  +EY FRVRA N  GT  P++   +   T
Sbjct: 12027 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12086

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
               +KP  P D  EV+   ++E  V +     +  + ++ ++
Sbjct: 12087 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12126



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)

Query: 622   APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
             AP   + + D+    G    ++ Q+ G P P++ W   G E+ +S  +     G  H+L 
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286

Query: 682   IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
             +     ED G YTC A N  GEV T + L +Q       P +  K +   A +G ++ + 
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24344

Query: 742   CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
                 G P P + W   G+ L +++ +  +   E    LV+K VQ   HAG+Y++ L N  
Sbjct: 24345 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403

Query: 801   GECSCQVSLMLQN 813
             G     + + +Q+
Sbjct: 24404 GTVDAILDVEIQD 24416



 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)

Query: 416  FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            F  + Q    KE  T+  F CE S  P  +V W+ +G  V   +    ++ D   H+L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
            L   T D+  YSC     +   + +      +L V      F   L+D  V E     L+
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241

Query: 535  CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
            C V    +    W  N   ++       T   G   L ++D   ED G Y+ + +     
Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                       KK++ K +        KP     LQGLSD KV +G  V + V+VS    
Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338

Query: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
             E +W+ +G E+Q S+  H       H L I+++  ED G Y+        +++G V   
Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
            +V              I+  + V    G   ++ C ++     +V W  + + + K    
Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
             + +       LV+ +      G Y++++  RV E +C +S+
Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            + E ++  F  E+S    P   W L+G  + R   + E+  + G  +L L K +   +G 
Sbjct: 5103 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 5160

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
                A NA         +    L V E+   F+  LKD  V E +    +C +  T    
Sbjct: 5161 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5209

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
            + W      I+ +         + HI    D+  +D G YT   E    + S   +VT  
Sbjct: 5210 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5267

Query: 602  EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
              K                    F+  L D  V +G   T   ++S +    V+W  N  
Sbjct: 5268 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5306

Query: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
            ++  S        G  H L ++EV  +D      +      E+ + A L V E      P
Sbjct: 5307 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5358

Query: 722  WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
            +F  K    TA     + + C ++ D    V W +DG+ +      + +  +     L +
Sbjct: 5359 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5415

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
            KK      G+Y          C C       N +  A L +  +P    ++  G      
Sbjct: 5416 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5466

Query: 838  ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
             +    D +G     W  +GQ      D E +    K  +         T + + +A   
Sbjct: 5467 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5522

Query: 890  QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
            +    L  ++L    +    LS  D+K    ++  F   + R+  PKT     R +   Q
Sbjct: 5523 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5572

Query: 950  QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
            ++  D R  L K GT  + V +       A   F +      +    +G    E +  K 
Sbjct: 5573 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5626

Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
            +   K ++  +    +  V  +     +K   N +   T + + + + +    S + ++L
Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5685

Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
              D  + +  +    G +   K +  +G  P F  KLQD    E  +++LQC++S    A
Sbjct: 5686 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5741

Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
             + W  +GK +K +K  ++  +G    + ++KAL  D G Y C    D G  + S ++ +
Sbjct: 5742 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5797

Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
            +D          E+K  RP  S+  V+ TE+
Sbjct: 5798 EDR---------EIKLVRPLHSV-EVMETET 5818



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PPKA +  ++    +   +RAG  + L   V G       W K  K++   E + ++ + 
Sbjct: 22738 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               +   I    +   G YTL V+N  G++   V + V+D P  P G    S +     TL
Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22854

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y +E  +++   W  +   C + S+ V  L+ ++EY FRVRA+N 
Sbjct: 22855 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22914

Query: 1410  YG-----TSEPSQESELTTVGEKPEEPKD 1433
             YG      SEP       T+   P  P++
Sbjct: 22915 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22943



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AG+++++   V G    T TW K  + +++++ +  E +   + L I    +   G Y 
Sbjct: 14773 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14832

Query: 1310  LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             L   N +G     + + V D P PP G     ++ S  +T SW     DGG  + +Y +E
Sbjct: 14833 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14892

Query: 1370  IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
             +  + + TW ELA T   T++    L    EY+FRV+A N YG
Sbjct: 14893 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14935



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)

Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
            EED  +     ++E +  V+  F   I++  ++EG    F CK+ GYP P++ W+KD + 
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284

Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I+    +Q+D+ +DG  SL I  V  +D+  YT  A N  G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)

Query: 21   PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
            P +++  P  EAP      ++  + +G+ A F  RV G P+P+  W++NG  I    R  
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079

Query: 81   LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
                      LVI  V  ED      +A N +G       L V+   AKQL         
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127

Query: 141  GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
                                  F  +L  VV KE   M  F C+ T  P  +V W K  +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             +    +  +     +  L I  ++  D   Y+C++V        +A+L ++G   A   
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222

Query: 260  FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
            FV+E +          E+  ++S E+       + +E  +  K   + +RG       + 
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282

Query: 313  QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
              +   E       K  +CK   +  P   +LQ  S     +   VQ E +       GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341

Query: 364  LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
                G+E  +P+         +   L  +D+  + A      IP  G   S      S  
Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400

Query: 421  QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                +K+   ++       C+VS      V W+L    + + +  ++         L + 
Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
            +    D G Y        G++  +  L VE++ ++         L+D    E Q+ V + 
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508

Query: 536  SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
             +  + +  + W    + I+ +   +      + +L + + + +D G YT  A    G+ 
Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563

Query: 593  SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
              S  +TV               A SKP        L+D  V +  +     +V+ NP  
Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602

Query: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +  WL +G  +  + +   E  G +  L I     +D G YT +   S    +T A L V
Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658

Query: 713  QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            +          I K  +++T +  Q  + +  +       V W+++G  L
Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
             P+F     ++     + V+F   ++  P+P V W+  G  ++  +   +     D G + 
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
             L +    T D   Y+  A N  G+ SC   L V          + P F  +L +    EG
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25504

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
             Q    +  V G P P + W  +GQP+    +      G+    LHI+D LPED G Y   
Sbjct: 25505 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25564

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEY 611
             A N  G  SC A + V E+   +K E+
Sbjct: 25565 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25590



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)

Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
            +P+  TPP  A+ P  I  P+       +V+ G+ + L   ++G+   T TW+K      
Sbjct: 8359 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8416

Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
                             ++QE E         + ++NS+ G S+L +  + +   G Y +
Sbjct: 8417 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8476

Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
             VEN  G  +A   ++V+D P PP       DIR +S+   W     DGGS + +Y++E 
Sbjct: 8477 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8535

Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             D    +  W  + +T R   ++V  L+   EY FRVRA N +G   P     L  V + 
Sbjct: 8536 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8593

Query: 1428 PEEPKD 1433
            P  P D
Sbjct: 8594 PFGPPD 8599



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)

Query: 36   ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
            I P +++ + EG  A  E +V       V W+ N + I    R  +   ++GT   LVI+
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459

Query: 95   AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
              H  D G Y        G  +    L+VE                              
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487

Query: 155  IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
                   K    L  +   E Q   F  +++      V W   +  ++PS++  +     
Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539

Query: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
            +  L +  + +DD G YT      +G+   S +L++ G  + ++    +T A + +    
Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594

Query: 273  KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
             EV N  SK   L   +    + N  S   G        A           K+ + K S 
Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654

Query: 330  RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
            +   +   ++KT  ++T+   +          P   G+     GV+  S E+        
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              +   +   +  + V      R +    +      K   KP+     EN TV F   VS
Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
                P V WF +   ++  +    +  +   H L L      D+G Y+       GQL C
Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
               L VE L +       +  +K+  V E +    +C V    VP + WL NG  I+ + 
Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879

Query: 559  S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
                  +  + +L I +   ED   YT +  N   QVS +  VT                
Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921

Query: 616  APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
                   PI +   L D+   +   +T  V V+        WL NG EI+ ++      +
Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973

Query: 675  GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
               HSL I+ V   D   YT      AG+  + A L V+  H      F    + +    
Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             +  +  C ++ +P  TV W++D + L + T   ++ + + V  L++   +   AG+Y +
Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083

Query: 795  LLKNRV 800
            +    V
Sbjct: 3084 VAGGNV 3089



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)

Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
            P T   A + P   +  F +  +V     + +    TG    T TW    K ++  + +K
Sbjct: 7078 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7137

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
            ++     ++L I  + +   G YTL +EN++ +   ++++ V+ +P  P       DI  
Sbjct: 7138 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7196

Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ L+W     DGGS +  Y +E  + + KTW K +       F V DL+   EY F+V
Sbjct: 7197 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7256

Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
             A N  G  EP+   E   ++T    P+ P++
Sbjct: 7257 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7288



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PA  ++L  V  ++   +L   +   D  + I   L     K + F + +      + ++
Sbjct: 22241 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22300

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             E+ + +    ++  AKNDAG +E                         P+ +   V+   
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22332

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                 +K+     T     +  Q+I        +AG    +   ++G      TW     +
Sbjct: 22333 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22382

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
             ++E++ + +  +++ + LT+  + +   G Y L +EN  G +   V + V+ +P P  G 
Sbjct: 22383 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22442

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
                S + + S  LSW      GG+ + +Y +E  +S    W+ + ++ + T   V  L  
Sbjct: 22443 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
               EY FRV + N +G S+P + + +  + E P  P
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22535



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)

Query: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
            S+DVV    +      G  + A P F +KP  Q++ E  +V F C+V G PKP V W   
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072

Query: 451  GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
            G P+       +   +  G   L +      D+G Y+    N  G+ S S +L +E    
Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131

Query: 510  MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
              +  S   +L    V     FV +  V G   P   +    +  +  ++     +A+  
Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
            + ++  + +     +   E  + ++      T  E+  +   + +  + ++ S+     F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247

Query: 626  LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
               + + ++++G  VT   ++SG P P++ W  +G  I+  E +   F Q G + SL I 
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306

Query: 684  EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
             V PED G YT  A N  G       L V+       P +I             PRSV+ 
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366

Query: 733  S 733
            S
Sbjct: 1367 S 1367



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P  K       V  G+ L ++  +S  P  TI WT +G  LK T  I ++    L ++SI
Sbjct: 16925 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16984

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y     N  GQ   S ++   D P  +  K P                  
Sbjct: 16985 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 17027

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              D + +       PP      QI  +   ++                   T  W      
Sbjct: 17028 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17071

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
             +  +  +KV   + G++             + +  EN+ G   A  +  +V      +P 
Sbjct: 17072 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17119

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
             PP GTP A+ I   S+ + W+    +GGS V  Y +E       +W   NKT        
Sbjct: 17120 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17173

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              T F  Q+L    EY+FRV A N+ G  + S+ SE     +  + P
Sbjct: 17174 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17219



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F + L+D  V E    +  CQ+S +  A + W  NG+ +K  K     ++GS+  + I+ 
Sbjct: 6520 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6578

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
               +D   Y C  ++   +A    + + V+         +AP ++     E+   +    
Sbjct: 6579 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6638

Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
              ++++  V G +                           + K    +   + A  P+I 
Sbjct: 6639 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6698

Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
               +D  V  G+ + +             W K  + +       ++ +   +   IL A+
Sbjct: 6699 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6755

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            +   G Y ++++NK G  +  +NL V+D P P       ++     ++L+W     DGGS
Sbjct: 6756 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6814

Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
             +  Y +E  D   KTW  LAT R+ S  F V  L     EY FRV A N  GT EP + 
Sbjct: 6815 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6873

Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
                    K + P   + V+  D
Sbjct: 6874 DNPVEARSKYDVPGPPLNVTITD 6896



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)

Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
            S TG+       E L   E  V++        E P   P     ++++ V+EG +   +C
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             I GYP P V W+++D  I  S  FQI + + G   L+I +   +D  ++TC AVN  G 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 1840 ATCTAELIVETMEEGEGE 1857
             + +  L V+  EE E E
Sbjct: 978  VSTSCYLAVQVSEEFEKE 995



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)

Query: 619  KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
            K   P+    L D    +G  V +T  ++     EV W      +   E F   Q    +
Sbjct: 4431 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4488

Query: 679  SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
            +L I +V  ED  G Y CEA N +G+  T A LTV +      P    K   +  +LG  
Sbjct: 4489 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4545

Query: 738  VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
               +C I   P     W + G+ +  ++    +  ++ + +L + + Q    G+Y     
Sbjct: 4546 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4604

Query: 798  NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
            N  G  SC  +L +         R L   R+P   E++                S+    
Sbjct: 4605 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4651

Query: 854  PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913
            P   +  +E +  E V    K+         + + + EV  +  R+   +K+   T   +
Sbjct: 4652 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4704

Query: 914  DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970
                IP    + +   + +V   KP  V  E   + +P  V    V+ KK  +K P  E 
Sbjct: 4705 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4761

Query: 971  VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027
              P  P       + G  KK P+   +   +       E      P +    + PLK V 
Sbjct: 4762 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4814

Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073
              K     +   +G++   E L     A     K   N++ + K     D K+       
Sbjct: 4815 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4874

Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124
                   +  C  + G+   T   K    +      K   ++V V +G+ L L C+++ +
Sbjct: 4875 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4934

Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183
                ++W  +GK  ++    I+    G + +++I  A   D G Y    +N A   ECS 
Sbjct: 4935 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4991

Query: 1184 QVTV 1187
             V V
Sbjct: 4992 CVKV 4995



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)

Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
            N++P ++LK   +E +  D +  +  +  +A G ++  + SE+         P    +  
Sbjct: 8030 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8089

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            D+ V EG+KL +     + P  T+ W  +GK +K +  + +  +     + + K++  D 
Sbjct: 8090 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8149

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            G+Y    +N  G A  S  V V   P        ++K+              SD T    
Sbjct: 8150 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8191

Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                 PP+                             G  PI   ++  R++     ++ 
Sbjct: 8192 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8223

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
            V + EN    T+          + +   NK+G  +     N  +   P  P   P   ++
Sbjct: 8224 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8283

Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
             +    ++T++W    YDGGS +  Y IE      + WK    C        ++  + L 
Sbjct: 8284 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8340

Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
               EY+FRVRA N  G SEPS+ +  T   +  + PK      +EV   DE
Sbjct: 8341 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8391



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            VKE Q V F CEV+     +  WF     +      I + +D   + L +  A   D   
Sbjct: 6346 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6403

Query: 485  YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
            Y+ + +N +G+ +  +  L VE   +  V P     LKD   +E +     C V    V 
Sbjct: 6404 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6458

Query: 544  RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
             + W  NG+ + +            H   I+D    D G Y                VT 
Sbjct: 6459 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6502

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
             + KS   +E L+  AP++     F++ L D  V +      + Q+S      V W  NG
Sbjct: 6503 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6554

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
             EI+E + + FE+ G+ H L I++   +D   Y C       + +++A L V+E P +  
Sbjct: 6555 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6610

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
            +P     P+ +  + G  V+    +  D    V WLR+   + +   H +++    +  L
Sbjct: 6611 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6663

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             +  ++P   G+Y  + K++      +++
Sbjct: 6664 QICDIKPRDQGEYRFIAKDKEARAKLELA 6692



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V+V  G  L +   +S  P   +  + +G  LK T            ++++++++  D G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
              Y+  A N +G  +    + V D P                   P V+   TE   T+K 
Sbjct: 20241 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20286

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P PK    + +   I+       ++   S  ++ +V+ T  +  T MK  K     E+ 
Sbjct: 20287 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20336

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
                 +EN                    + + + S    V L     P PP+ TP  +++ 
Sbjct: 20337 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20377

Query: 1345  SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
               S+T+ W+    +GGSAV  Y +E+ D  +  W++      R+T F V  +     Y+F
Sbjct: 20378 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20437

Query: 1403  RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             RV A N  G  +PS  SE     +  E P++ V ++D  +    + ++    +   K++ 
Sbjct: 20438 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20496

Query: 1463  FYDIEER 1469
              Y +E R
Sbjct: 20497 -YIVERR 20502



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 33/91 (36%), Positives = 56/91 (61%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P+F K ++ +   +G  A F+  + G P P V WFK+++ +  S ++ I ++ +G+ + I
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            ++D   +D   Y CKA N LGE+TC AEL+V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
             R+++ ++    +++   G+ L +   ++     + +  EN+ G      S +     T +
Sbjct: 23962 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 24021

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
             + P+PP+  P   D+  SS++LSW     DGGS V  Y IE  +++   W         +
Sbjct: 24022 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24081

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
             T + V  L+PD EY+FR+ A N  G SE S  SE        +KP +P  E+E+
Sbjct: 24082 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24134



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)

Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
            P+ PP   +    +      ++ AG+++ +   VTG    T  W K   ++ + + + ++
Sbjct: 8793 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8848

Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
            N    S+L I  A ++  G Y +   N  GS+ A   + V D P P          R   
Sbjct: 8849 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8908

Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
            L L+W     DGGS +  + IE  D+   TW++      +  ++  LL   EYKFRV A 
Sbjct: 8909 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8967

Query: 1408 NVYGTSEPSQESELTTV 1424
            N +G   P +   +  V
Sbjct: 8968 NKFGCGPPVEIGPILAV 8984



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             +D P PPA    A D   SS+TL W    YDGGSAV  Y +EI     + W  ++T    
Sbjct: 20859 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20917

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             R+T + V +L P   Y FRV A+N  G  EP + +E     +  E P+ +++V+
Sbjct: 20918 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20971



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)

Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
            P T  W++  K   +    +V+   N  K             + +L EN  G  +   + 
Sbjct: 7619 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7667

Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
              + + D  DPP   G P   D+  +S+ L+W    +DGG+ ++SY IE+  +    W  
Sbjct: 7668 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7727

Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
            +A    +T   +  L+   EY FRVRA+N  G SEPS+ S+     EK  P  P   +EV
Sbjct: 7728 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7787



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+  +VA +   ++S+SV  + V+++     P F+   +N+ IKEG+  + + R  G P 
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538

Query: 62   PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P + W +N   I      +  ++ G +G  +L I +   +D   YT  A N +G      
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597

Query: 120  ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
            ++ VE  FA+   +  +    G       +AP +E     +G              +  P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657

Query: 162  KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             F  KL  + +K      F C++T  G P   V WL    PL+ + R+ +  + G   L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
                   D G+ TC   N  G    SA L ++      +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)

Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
            SE +GT P F +++ +  ++ G    L   V   P   I W  NG  L  +       +G
Sbjct: 3642 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3701

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               S+ I     ED G Y C+A ND G+  CS  + +       N+K    K        
Sbjct: 3702 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3747

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
                 TE+++ V K       P    PP  ++  +  +   G        V G    T T
Sbjct: 3748 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3799

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
            W K  KQ+  S +  + ++ NGS   I+   ++E  G Y    EN LG       L V+ 
Sbjct: 3800 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3859

Query: 1330 KPDPPAGTPC 1339
            +      TPC
Sbjct: 3860 EDTDMTDTPC 3869



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V V  G  + L+      P  +I W  +G  LK ++F+  S+  +  ++SI+ A  E  G
Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21327

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y  +  N        C++ V   P +  T  P  K + P                    
Sbjct: 21328 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21358

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
                           I+F E +     +SV L   V    G   ITC  ++ R+  Q +  
Sbjct: 21359 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21400

Query: 1284  MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
             M   + +    K+  L    E+   + +  EN+ G  Q  V+  +V K     P PP G 
Sbjct: 21401 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21457

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
             P   ++ S  ++L+W    YDGGS V  + +E  +  +  W+++ T       +    L+
Sbjct: 21458 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21517

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
                +Y+FRV A N  G S PS  S+  T+   P +P    +  D       V   T+T+ 
Sbjct: 21518 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21569

Query: 1456  TEQKVSD------FYDIEERLGSGKF 1475
                 + D       Y IE+R G+ ++
Sbjct: 21570 WNPPLRDGGSKIVGYSIEKRQGNERW 21595



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+V   A + I+   L+V    +D         F +P +++ + E   A+FE  +    E
Sbjct: 5159 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5207

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W +    I S  +F +    +    LVI+    +D G YT E              
Sbjct: 5208 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5252

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
             VEG            K    R     +            KF + L    VKEG+   F 
Sbjct: 5253 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5289

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C+++   +  V W K +  L  S  V +S +     LE+  V  DD+      V     +
Sbjct: 5290 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5344

Query: 242  ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
             S +A+L +   D      + +  A   D       V K+V     K+            
Sbjct: 5345 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5404

Query: 284  KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
            K D L    K K      +G      G+    AN   +  R  K+E     P    +  V
Sbjct: 5405 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5459

Query: 338  LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
             +     I L    V  + +  G  + +    E               Q G+ + +V  +
Sbjct: 5460 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5518

Query: 398  AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
            AAN +      +    P     P S  +V E    KF CEVS  PK    W L+GT    
Sbjct: 5519 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5575

Query: 457  QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
             +   E+ +D   H + +  A   D   Y   A +              +L +  +   F
Sbjct: 5576 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5626

Query: 517  SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
             + LKD    E +  V    +    + R+ W  N Q +   RS        + +QD    
Sbjct: 5627 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5677

Query: 577  DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
               T+  L+ +   Q+   A            SE  L V       P F   L D   ++
Sbjct: 5678 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5726

Query: 637  GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
              +V +  ++S    P V W  +G EI+ S++   +  G +  L +++    D G YTC+
Sbjct: 5727 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5785

Query: 697  AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
                 G  +T   L +++     +   +    SV     ++      I+ D     +W  
Sbjct: 5786 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5836

Query: 757  DGKALCKDTGHFEVLQNEDVFTLVL 781
             G+AL + T   E+ +   + +LVL
Sbjct: 5837 KGEALLQ-TPDCEIKEEGKIHSLVL 5860



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L  + V  G K+ L   V+  P   I WT     LK  K I +       +V+I  +   
Sbjct: 7392 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7451

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y   A N  G+A    +V V D P                   PP     +D T +
Sbjct: 7452 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7493

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                   PP+     +I  +  +++    E                 W K    ++++  
Sbjct: 7494 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7537

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
                      K T L   +E+   + +  EN  G     Q + +T   + DPP G P   
Sbjct: 7538 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7584

Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
              SDI   ++TL+W     DGGS +  Y +E  D     W        + T++ V+ L  
Sbjct: 7585 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7644

Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              +Y+FRV A N+ G  +PS+ +E   + +  + P
Sbjct: 7645 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7679



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
            P F++ ++ + V+EGS A F+  I G+P PEV WF+D Q I  S     QI +  DG   
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L I  V   +  +Y+ KA N  G+AT TAEL+V+
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)

Query: 1217  ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
             ESD  V + P      P TP   A+    +     + V  G S  +   +   +  +  W
Sbjct: 17105 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17164

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
              K  K I      K +N E G +             + +  EN +G  +A  N       
Sbjct: 17165 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17213

Query: 1332  DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
             DP  P GTP    ++ + +TL W    YDGGS +  Y +E  D  +  W + +      T
Sbjct: 17214 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17273

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
              F V  L  D  Y+FRV A N  G  S+PS  +   T  ++ E P        +D + V+
Sbjct: 17274 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17333

Query: 1439  DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
               +    E D     + T + +    +IEE          F+  L+ K   ++  G++  
Sbjct: 17334 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17393

Query: 1496  KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
             +A +    ++    + +++    P+  VQ      EK ++     +  GG      + E 
Sbjct: 17394 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17453

Query: 1555  FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
              E       +   E +    +++   EG EY+ +            IM VNK G
Sbjct: 17454 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17495



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
             GC   Y +  EN  G         ++   DP     P   P   D   +++T++W    +
Sbjct: 19745 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19804

Query: 1358  DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             DGG+ +  Y++E   S +  WK  + + R T + +  L    EY FRV+++N  G S+PS
Sbjct: 19805 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19864

Query: 1417  QESELTTVGEKPEEPKDEVE 1436
               S+     E+ EEP  +++
Sbjct: 19865 DSSDPQIAKEREEEPLFDID 19884



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)

Query: 263   ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
             E     S  ++EVT +   E + +  + A +  + S+ +     R  SP +         
Sbjct: 25924 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25983

Query: 311   --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
                S+PQP  E + ++ + SP     TP                +  PR+P     SP  
Sbjct: 25984 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 26018

Query: 369   EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
              ER      R A F   +R   + +     K + R+  +  Q+       P+   + +S 
Sbjct: 26019 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 26078

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              V   Q  +F   V   P  EV W+  G  ++ +   I     +G   L +L   T DSG
Sbjct: 26079 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 26137

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
             TY    +N +G+ S   TL V                       G D+    S R    V
Sbjct: 26138 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 26175

Query: 543   PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
             PR  +    +   YA S+       EA  +   ++  + E   + +    +A  ++  +A
Sbjct: 26176 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26235

Query: 597   WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
                 ++ EK ++RK +  L        A   L     + V +G     +    G P P V
Sbjct: 26236 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287

Query: 655   IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
              WL  G  +  S          + +  I  V   D G Y+    NS G+   +  LT+Q+
Sbjct: 26288 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26347



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             L  AP   L  R+  +  G   +F   V+  P  +V W+ NG  +    +        G 
Sbjct: 26065 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26123

Query: 89    FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
              +L I   H +D G Y               T + T G               R V  EL
Sbjct: 26124 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26183

Query: 122   TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
             T   ++A    K+  +   S ++ +   +   ETR S+                      
Sbjct: 26184 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26242

Query: 158   ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                           +  TK   + V EG+  RFSC   G P P VTWL+    L  SAR 
Sbjct: 26243 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26302

Query: 208   SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
              V+        EI  V   D G Y+ +V N  GK      L+IQ      ++ V E KA 
Sbjct: 26303 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26355

Query: 268   NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
              S  R     V S E ++ S EA    K   SP+    P       P   + +  E  + 
Sbjct: 26356 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26406

Query: 328   SPRTAP 333
              P +AP
Sbjct: 26407 LPVSAP 26412



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%)

Query: 444  EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502
            EV W+ E   V   E   +  +D  ++ L + K  T D  G Y C A N  G+ + S  L
Sbjct: 4463 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4521

Query: 503  QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562
             V    V   AP     ++   V  G      C ++  P  R  W   G+ I Y    C 
Sbjct: 4522 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4576

Query: 563  AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
                  ++ L I      D G YTC A N  G VSC+A +TV      +K   LLP    
Sbjct: 4577 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4636

Query: 619  KPTAPIFLQGL 629
            +P   + L+ +
Sbjct: 4637 EPKEEVVLKSV 4647



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)

Query: 1098  PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
             P    KL  V  V  G  + L+  V   P   + WT +      T+   + +        
Sbjct: 11896 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11955

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
              S+ KA   D G Y   A N AG       V V D P    N K  ++ S R        
Sbjct: 11956 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 12007

Query: 1214  LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                    TV   P P+      +   I++  E +++                     W  
Sbjct: 12008 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 12040

Query: 1274  FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
             +   +             G+ +T L    E+   + +  ENK+G+     +  V+ K   
Sbjct: 12041 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12088

Query: 1331  -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
                  PDPP  T  + +     +T+ W    YDGG ++  Y +E  +  +  W  +  + 
Sbjct: 12089 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12144

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                    VQ+LLPDHEY+FRV+A N  G  EPS  S    V + P EP
Sbjct: 12145 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12191



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ +      +V   ++L +       P AT+ W  +G+TLK T  + +S   ++ S+SI
Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19149

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++A  ED G Y+    N AG       + V D P                   PP     
Sbjct: 19150 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19191

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              + +         PP+     QI  +  ++K                +  + TW    + 
Sbjct: 19192 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19235

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
             +  +  +K+     GS+             + +  EN+ G      +  VV +    P  
Sbjct: 19236 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19283

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
             P GTP       S++ ++W     DGGS V  Y +E       +W  ANK          
Sbjct: 19284 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19338

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
             T   V  L     Y++RV A N+ G  + S+  E       P +P  + EV++   K   
Sbjct: 19339 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19397

Query: 1447  VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
             + +     +   K++ +      L  G++
Sbjct: 19398 LKWSKPHYDGGAKITGYIVERRELPDGRW 19426



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)

Query: 1091  SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
             S+    APAF  + +  ++ EG+ +L  C++S +P   I W  N   +  +  + +S+  
Sbjct: 26822 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26881

Query: 1151  SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
             ++ S+ I  A   D G Y   AKN  GQ   +  + V    + P+ E             
Sbjct: 26882 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26941

Query: 1195  --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
               ++++ +M + + ++S      + + +  + K A  +    +                 
Sbjct: 26942 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 27001

Query: 1236  --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
                                 +PP+I   P D  +  G+ + +    TG      TW    
Sbjct: 27002 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 27061

Query: 1276  KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             ++I  QE     +EN+++ + L I+  +++  G YTL + N+ GS  A VN+ +
Sbjct: 27062 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 86/356 (24%), Positives = 138/356 (38%), Gaps = 82/356 (23%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
            P   Q+LQ V V  GK       +S  P   I W    + L T    KF+   QE +L  
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            +   +A PED  +Y C AKND G A  S  ++V+          PE+ S  P   +P   
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP II   +D     G+      +V+GT  +  +W   
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV-VDKPDP 1333
             K+I+ S   ++   E+  +L I  A  E  G YT +  N +G   +  NL++ V   D 
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDR 3394

Query: 1334 PAGTPCASDIRSSSLT--------------------LSWYGSSYDGGSAVQSYSIEIWDS 1373
             +      D+R S+ +                     S+ GSSY+       Y +++++S
Sbjct: 3395 QSS---GKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSSYE-------YEVQVFES 3444

Query: 1374 ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
             ++      +   T+ +VQD    H          +  ++E S+E    + GE P+
Sbjct: 3445 VSQ------SSIHTAASVQDTQLCHTASLS----QIAESTELSKECAKESTGEAPK 3490



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
            S +  S A L   AE  P   P F + ++ + V +GS  R   ++ G P P V +++D  
Sbjct: 86   SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142

Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I+ S  FQI  + D   SL+I++   +D   Y+  A NS+G AT TAEL+V+  EE
Sbjct: 143  EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)

Query: 1104  LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
             ++ + V  G  +     +   P  T  WT +G  +KT +   +  +     ++I+  L  
Sbjct: 11212 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11271

Query: 1164  DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             D G Y+    N AG    +  +TV D P              P   +  +  T    T+ 
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11319

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P    P      P I    E Q  R     + +G V+                     
Sbjct: 11320 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11350

Query: 1284  MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
                    +GS  T L       GC   + +  ENK+G      +   V K    P  P G
Sbjct: 11351 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11403

Query: 1337  TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
              P  +DI  ++ T+SW     DGGS +  Y +E       W   NKT           F 
Sbjct: 11404 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11458

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             V  L   + Y+FRV A N+ G S+PS  S+
Sbjct: 11459 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11488



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + L   V   P  T+ W  +G  LK  + I ++ + +LC++ +     +D G Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
                A+N +G    + ++ V D P    + K  +M S R   S  P L   G+E    +  
Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13121

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             K     P  A                         +V+ T PIT   ++  K I+  E+ 
Sbjct: 13122 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13154

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
                                    + +  ENK G          + K   DPP     P  
Sbjct: 13155 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13191

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
             S+I    +T+SW   + DGGS +  Y +E  ++    W ++        +     L    
Sbjct: 13192 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13251

Query: 1399  EYKFRVRAINVYGTSEPSQESE 1420
             EY+FRV AIN  G  +PS  S+
Sbjct: 13252 EYEFRVTAINKAGPGKPSDASK 13273



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)

Query: 1083  GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
             G +D    S+ Q      ++ L D+     K L+++   S          P   ++W+  
Sbjct: 19859 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19918

Query: 1135  GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
                L+T  ++  +   S  S++IE A   D G Y    +N    A  +  V V D P   
Sbjct: 19919 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19974

Query: 1195  NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
                             PP   T  D T +          A +   +   PE+        
Sbjct: 19975 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19999

Query: 1255  VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
                     G  P+    ++ R   + S+   V  + N ++L+      +    Y   V  
Sbjct: 20000 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 20048

Query: 1313  ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             EN+ G     + +  + + +KP PP      S I   S++L+W    +DGGS +  Y +E
Sbjct: 20049 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20107

Query: 1370  IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
               +   K W + A  +ST   V  L  + EY FRV A N  G S+P +      + E+ E
Sbjct: 20108 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20167

Query: 1430  EPKDEVE 1436
              P+ +++
Sbjct: 20168 PPEIDMK 20174



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            + +  GK L +   V+  P  T +WT     L   + +++   G+   + I+ AL +D G
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8867

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
             Y   A N  G    + +V V D P              P   L PV+ T     +    
Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8913

Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P+    + +   II+  +D K+            T  QPI            E+E  K 
Sbjct: 8914 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8949

Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
            +       +T L   QE+   + ++ +NK G     ++  +  VD   PP        ++
Sbjct: 8950 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 9000

Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
               S++TL W     +GGS +Q Y IE        ++ +    C +TSF V++L     Y
Sbjct: 9001 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 9060

Query: 1401 KFRVRAINVYGTSEPS 1416
            +FRV+A+N  G SEPS
Sbjct: 9061 EFRVKAVNEIGESEPS 9076



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G+   L+  VS  PP T+ W+ +GK L+ T  + +       ++  + +   D G Y   
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15230

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A N  G A+    V V D P              P      V    S+  V     P   
Sbjct: 15231 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15277

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I+Q  E  ++                     W     ++Q ++         
Sbjct: 15278 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15308

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
               K+T L    E+   + ++  NK G  +   +  V+       PDPP   P  + I   
Sbjct: 15309 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15364

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ + W     DGGS + +Y +E  D A + W +    T     + V  L   HEY+FR+
Sbjct: 15365 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15424

Query: 1405  RAINVYGTSEPSQES 1419
              A N  G S PS  S
Sbjct: 15425 MAENAAGISAPSPTS 15439



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +L EN+ G     +   ++   ++P PP G     D+  +S++LSW    +
Sbjct: 15711 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15769

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             DGGS +  Y +E+    +  W   AT + T   +  L+   EY FRV A N  G S+P Q
Sbjct: 15770 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15829

Query: 1418  ES 1419
              S
Sbjct: 15830 LS 15831



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PP+  P   D    S++L+W    YDGG+ +  Y +E+ +     W  +   AT R+T
Sbjct: 23037 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23095

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
              F V DL    +Y FRV A+NV G SE S+        E+ E P  ++E++DD +K
Sbjct: 23096 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23149



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
             +AP F    RNL ++  + A    +V G+P+P V W+R G+ I + G ++ +     G  
Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24680

Query: 90    SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
              L+I +V ++D   Y   ATN  G+   T  L VE      L                  
Sbjct: 24681 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24722

Query: 150   ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
                        PK    +G V    G++       +G+P P +TW KG   +  +    V
Sbjct: 24723 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24771

Query: 210   SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
                     L   +GV + D G Y     N  G    + EL +  +    R          
Sbjct: 24772 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24825

Query: 269   SDVRKEVTNVISKESKLD 286
             SDV ++  N+   E   D
Sbjct: 24826 SDVSRDSVNLTWTEPASD 24843



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ K       +  G+ L ++  V   P   I W  +G+ LK T  + + +  +   + I
Sbjct: 18007 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 18066

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y   A N AG A  +  V V + P                   PPV    
Sbjct: 18067 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18108

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  +         PP      QI  +  +++                   T TW     
Sbjct: 18109 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18152

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
              +  +  +K+   + G++             + +  EN+ G      +  V+      +P
Sbjct: 18153 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18200

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
              PP GTP  + I    + + W+    DGG+ +  Y +E  +  +  W +L     + T F
Sbjct: 18201 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18259

Query: 1390  NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 L    EY+F+V A N+ G  +PS+ SE     +  + P
Sbjct: 18260 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18301



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)

Query: 9     SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
             S+ + + SL  + S    +  T A   +  PR++ + EG +A+F     G P P VTW R
Sbjct: 26233 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26291

Query: 69    NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
              GQ +++  R  +     + TF   I +V   D G Y+    N  G ++    LT++ + 
Sbjct: 26292 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26349

Query: 127   -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
                K +  P   K+   R  +P                       ET+P+       +  
Sbjct: 26350 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
               PPK    L     KE  + + +C +        +VTW K    L+ +         +G
Sbjct: 26410 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26467

Query: 215   MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
                L+I+ + + D G Y C +    G +  + +   Q   S +    + ++   SD +  
Sbjct: 26468 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26527

Query: 275   VTNVISK 281
              + V  K
Sbjct: 26528 ESTVTRK 26534



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G+++ +  +V G      TW K  K +   + + +       +L I  A +   G Y
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11674

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              +  +N  G  Q    + V+D+P P       +++   + T+SW     +GGS + ++ +
Sbjct: 11675 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11733

Query: 1369  EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
             E      K W  +A+  +      +LL ++EY FRV A N  G   P+ E++   +    
Sbjct: 11734 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11792

Query: 1426  -EKPEEPKD 1433
              ++P EP++
Sbjct: 11793 IDRPGEPEN 11801



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)

Query: 1215  GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
             G +S+  V + P   P  PP    PP I+    D       SV L     K TG  PIT 
Sbjct: 13856 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13904

Query: 1270  TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               ++F  R  +      K        K+T L    E+   + ++  N  G  +  +    
Sbjct: 13905 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13962

Query: 1328  VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
             V   DP  P G P   +I  +S+TL W    YDGG  +  Y +E  D  +K+W +     
Sbjct: 13963 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 14022

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
                 +F V DL+   +Y+FR+RA N  G  S PS+ +E     ++ E P
Sbjct: 14023 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +  EN+ G     Q    + V + P PP G     D+  +S++LSW    +
Sbjct: 16793 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16851

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             DGGS +  Y +E+    ++ W E A  +S    + +L    EY FRV A+N  G S+P
Sbjct: 16852 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16909



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 95/427 (22%), Positives = 150/427 (35%), Gaps = 53/427 (12%)

Query: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS 1147
            E   ES G AP     LQDV V  G      C +  D    + WT  G  ++ ++ +  S
Sbjct: 3479 ECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQS 3538

Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEM 1201
            Q G++  ++I      D+GLY C+  ND G+   S  ++V+ AP S      E     EM
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEM 3598

Query: 1202 K----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPE 1245
            K                +    S +   L   S++ V   P      K    P  I+   
Sbjct: 3599 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVS 3656

Query: 1246 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHC 1305
            +  +  G+   L   V G       W      +  S   K     +   L IL  + E  
Sbjct: 3657 NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3716

Query: 1306 GCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-------- 1357
            G YT +  N  G       L +  K +    T   S +  S   L      +        
Sbjct: 3717 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3776

Query: 1358 ---DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEY 1400
                G  A+  Y++    +   TW    K+L T            S +F V D   +   
Sbjct: 3777 RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 3836

Query: 1401 KFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINT 1456
             +  +A N+ G S  + E     E T + + P + K   E  +D  + P        +++
Sbjct: 3837 LYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDS 3896

Query: 1457 EQKVSDF 1463
            EQ+++ F
Sbjct: 3897 EQEIATF 3903



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
             S+ TV + P  K P     P   +   +  +V+  E +   G +V G      +  +  W
Sbjct: 16024 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16082

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +K  K        K    E G +     + +   G         +G         V   P
Sbjct: 16083 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16133

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
               P G P A  +  +S+TL W   +YDGGS +  Y +E  +     W + +      T F
Sbjct: 16134 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16193

Query: 1390  NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
              V  L+ DH Y+FRV A N  G  SEPS+ +   T  ++ + P+
Sbjct: 16194 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16237



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L+  +S  P  TI W  + K L+T   + +     L S+ I+ A   + G Y+  
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20641

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G A  + +V + D P              P   +     T    T+  +P P   
Sbjct: 20642 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20688

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I++  E  +V                     W         SEH++    E 
Sbjct: 20689 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20718

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
                 T +    E+   + +   NK G  +   + +VV K     P PP G P  + I  +
Sbjct: 20719 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20775

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+ W     DGGS +  Y +E  D  +  W ++   T R T   V  L  + +Y++RV
Sbjct: 20776 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835

Query: 1405  RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
              A+N  G    S+ SE     +   P  P  ++ ++D
Sbjct: 20836 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20872



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 33/95 (34%), Positives = 48/95 (50%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P   + I+   V +GS A F  ++ G PDPE  W+K+   I  S      + ED  C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            I DV  +D A    KA+N  GE +  A L+V+  +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
            P  P   P   D   SS++L W   + DGGS ++ Y +E+ +     WK        + T
Sbjct: 9399 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9458

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
            C     N+++L    +Y+FRV+A+N  G SEPS  +      +  EEP+  +++   D
Sbjct: 9459 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9513



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
             + KP PP   P A D   +S+ L+W    +DGGS +  Y +E     ++ W+       +
Sbjct: 10805 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10863

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
             C  T + V  L     YKFRV A+N  G S+P+   E   V ++ E P+
Sbjct: 10864 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10912



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)

Query: 1006  KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
             K V +S PLS   P   L+     K + TL           L P+  G AK D  + S  
Sbjct: 12483 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12533

Query: 1064  KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
             +EE   D   + +  +  +    G  + +K                 E++G   A +Q L
Sbjct: 12534 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12593

Query: 1105  -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
                    + + +  GKKL ++  V   P  T  W      + T+  + + +  S   + I
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12653

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
             +    +D G Y   A+N +G      +V V DAP                   PP  +  
Sbjct: 12654 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12698

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
              ++DA       P     + +   I+   E   V  G+ V     VT T        +  
Sbjct: 12699 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12749

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
             K I   E++    +EN              G    L   K+    AQ    V  +P    
Sbjct: 12750 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12794

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
              T    D     + ++W     DGGS +  Y IE       +W  AN T       RST 
Sbjct: 12795 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12845

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
             +    L+   EY FR+ A+N  G+S PS+ +E  T    P +P  + EV D
Sbjct: 12846 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12895



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)

Query: 45    KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +EG   K+  ++  Y +  QVTW+   + + +  ++ +     G   L +  + + D G 
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25333

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
             Y C+  N  G      EL V+G   +++      +T+  +      +T   +  E PP+F
Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25387

Query: 164   ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
                L       G+  RF   IT  P+P VTW K    ++P     + +     G+  L I
Sbjct: 25388 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25447

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             + V  DD   YT +  N  G+ S  A+L++
Sbjct: 25448 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)

Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
            D EK+ +     P FK+KL  + +        +C+++   DP   + W  +GK L+    
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
            + +  E   CS+    A   D G+  C A N  G    S  + V D    E +   E + 
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760

Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
               +  L  +   E  A         T  K    P I+ +PE  +V  GE+     +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820

Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
                   W    + I++S+  +V   +    L I+  +    G   +  EN  G  + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879

Query: 1324 NLTVVDKPD 1332
             L +  + D
Sbjct: 1880 KLEIQQRED 1888



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
             KP PP   P   DI  SS+ LSW    YDGG  +Q Y +E  D +   W           
Sbjct: 16532 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16590

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             T+  V+ LL  HEY FR+ AIN  G  E +       V EK E P  ++++
Sbjct: 16591 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16641



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R    I GRP P+VTW K N+ L+  A +  +E     +L I   N+ D G
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14538

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
              +   + N +GK   S  ++++ LD+      +R T  T   V              +TN
Sbjct: 14539 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14596

Query: 278   VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
              I ++   ++     A  K   C+    G S          A N     +P   ++    
Sbjct: 14597 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14656

Query: 326   KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
              ++P       ++  T S+++L      P+P+  G   ++    E +R    +  T  T 
Sbjct: 14657 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14711

Query: 386   QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
               GL               Q +   +A R  P E      +  +  P+ + +   Q++  
Sbjct: 14712 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14771

Query: 426   -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
              K    +K    V G PKP V W  +G  + +Q   +     A S  L + +    DSG 
Sbjct: 14772 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14830

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
             Y  TA N  G++    T+QV  +      P  F  V  D
Sbjct: 14831 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14869



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
             AP     +KD     G+   L C + G P+P I W   G+ +  +R    + +     L 
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286

Query: 570   IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
             +     ED G YTC+A N +G+V  S             S+ LL   P   P  P+  + 
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24333

Query: 629   LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
                +    GS + + V   G P P + W H    +Q SE+   E       L ++ V  +
Sbjct: 24334 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24389

Query: 689   -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
                G Y  +  N  G V   A+L V+      +P   + P  + A L  S +IS
Sbjct: 24390 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24438



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            PP   + L  V V EG+     C I+G P P VTW + +  ++ S    ++ ++G+  L 
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            I     +D G +TC  VN +G  S S  L++Q     +  F +ET A        VT   
Sbjct: 956  IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003

Query: 280  SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
            + E K  ++S +      + +  Q G   P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
             +++      + V +       TI    + H   + ++ +NK G       + +    +  
Sbjct: 9951  KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
              P  P   P  S +  +S+T++W    YDGGS V  Y +E+ D+ +K WK +      A 
Sbjct: 10011 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10069

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 S+ V  L+   +Y+FRV AIN  G    S  S+  T  +    P
Sbjct: 10070 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10117



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             + V  G+ + +  +V   P   I WT  GK L   K + L Q+     + I++A+  D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y   AKN +G A+ S  V V D P              P  +L     T+ + T+    
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11716

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                            + P D                G   IT   +++RK  Q+   +  
Sbjct: 11717 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11747

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
              +         L A  E+   + +  ENK+G      ++   + +  +D+P  P     A
Sbjct: 11748 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11805

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
              D   + + L W    YDGGS   SY +E     +  W+ +   + + T + V   + + 
Sbjct: 11806 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11864

Query: 1399  EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
              Y+FRV+  N  G S+  +  E+  V E  ++P  ++++S
Sbjct: 11865 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11903



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
            T+  E   +++   P F Q+LQ + V +G ++ LQ +V+  P   + +  +G  ++++  
Sbjct: 90   TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
              +SQEG L S+ I +A PED G Y   A N  G+A  + ++ V   ++ PA +      
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
              +  E +  R +  +       S ATV+             K  P+ PPK    +  PP
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269

Query: 1239 QI 1240
             I
Sbjct: 270  SI 271



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            KP F       + +EG  ARFD K+ G P PE  WF D Q I      ++   EDG  SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            II      D  ++T  A N  G ++ +  L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)

Query: 1308  YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
             + ++ EN  G  +       +  +D  DPP G P   +I   ++TL W    Y GG  + 
Sbjct: 15026 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15084

Query: 1365  SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
             SY +E  D  N  W     +      F V  L  D  Y+FRV A N  G  S PS+ S+ 
Sbjct: 15085 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15144

Query: 1422  TTVGEKPEEPKDEVEVSDDD 1441
              T  +  E PK +V+V   D
Sbjct: 15145 ITCRDDVEAPKIKVDVKFKD 15164



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PAFK       V  G+ L +       P   + W  +   LK T  +      +   ++I
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15902

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A  ED G Y     N AG+A  +  V V D P                   PP    +
Sbjct: 15903 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15944

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  T         PP               K   G S+  +  V      T TW     
Sbjct: 15945 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15986

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
                         S   ++ TI A R +  GC   + +  EN+ G S       TV   P 
Sbjct: 15987 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 16033

Query: 1332  --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
                 P GTP  +     S+ + W     DGGS V  Y +E  +  +  W +L       T
Sbjct: 16034 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16093

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F    L    EY+FRV A N+ G  +PS+ SE   V   P +P    E          +
Sbjct: 16094 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16152

Query: 1448  DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
              ++  T +   K++ +   ++ L  G++
Sbjct: 16153 QWKKPTYDGGSKITGYIVEKKELPEGRW 16180



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P +K  +  VH  E  K+     +   P  TI W    + L  T  + +       S+S+
Sbjct: 16242 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16298

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A+  D G Y   AKN AG+   +  V V D P       PE          P V+   
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16341

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
             S  T +K      PP       II +  +++    E+  L   V     Q ++C      
Sbjct: 16342 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16391

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
                      KV     G++ T           + ++  NK G  +   +  VV K     
Sbjct: 16392 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16431

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
             PD P   P  + +   S+ + W   + DGGS +  Y +E  D     W            
Sbjct: 16432 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16490

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
               V  L+ +H+Y+FRV A N  G SEPS  S
Sbjct: 16491 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16521



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W+K  K   +    K    + G +     + +   G         +G         V   
Sbjct: 18246 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18296

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
             P  P G P A  I  +++TL W   +YDGGS +  Y +E  D  +  W +        T 
Sbjct: 18297 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18356

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
             F V  L+ D  Y+FRV A N  G  SEPS  S   T  ++ + P   ++
Sbjct: 18357 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18405



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
             AQ+  TV D P    G P  S+I  +S+TL+W     DGGS +Q Y +E  +  +  W +
Sbjct: 21840 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21895

Query: 1381  LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
             + + R    T F V  L   +EY+F V A N  G    S  S L    E   P  P   V
Sbjct: 21896 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21955

Query: 1436  EVSDDDEKEPEVDY 1449
             +V+D  +    +++
Sbjct: 21956 KVTDTSKTTVSLEW 21969



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
             P  P   P  +D   SS++L+W    YDGG+ V+ Y +E+ ++A   W    TC      
Sbjct: 18697 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18753

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
             +   F V  L  + EY FR+ AIN  G  EP+         E+ E P+ E++
Sbjct: 18754 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18805



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             +HV  G+ + L   ++  PP    W   G  L+ ++ + +     +  ++I +    D G
Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23502

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
              Y    KN  G    + +V + D P                    P+   E DAT   + 
Sbjct: 23503 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23547

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P P+    A +   +++  +  +          G +  ++ +T +  KF +  + +E+
Sbjct: 23548 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23597

Query: 1284  MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             +            + A  +   G Y   +++++   ++ + +     P PP  T    D+
Sbjct: 23598 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23638

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
                 +TL+WY    DGGS V  Y +E        W   NK    +   RST      L  
Sbjct: 23639 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23693

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
               EY+ RV AIN  G+ +PS+ S+     +      KP+ P+
Sbjct: 23694 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23735



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PPA  P   D   SS++LSW   +YDGGS +  Y +E+  + +  W         + T
Sbjct: 13284 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13342

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
              F V  L+ D +Y+FRV A+N  G S+PS
Sbjct: 13343 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13371



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)

Query: 1325  LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
             +   ++P PP       D   SS  L+W    +DGGS +  Y +E+    +  W E    
Sbjct: 22235 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22293

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
             +  +F V+ L+   EY+FRV+A N  G SEP +      + E   EP
Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22340



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P    + +    K  +  +  C++ G P P++ W+  G  +  Q    ++  D  +H L 
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24286

Query: 474   LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             ++     D G Y+C A+N  G++  S  L ++  A  +  P +    K    + G    L
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24343

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
                  G PVP +TW    + +Q + + T E      H+  ++   + H G Y     N  
Sbjct: 24344 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403

Query: 590   GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
             G V     V + +K             P KPT PI ++ L          +  +  +S  
Sbjct: 24404 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24440

Query: 650   PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
             PP +    W+ N      E +E  ++         + C      E+ G Y    A N+ G
Sbjct: 24441 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24500

Query: 703   ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
                 +   +V+ ++ P +  +P    KP ++TA        SC +A  P
Sbjct: 24501 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24542



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 28    PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
             P++  P  +   ++  +   + AKF  +  G P P   W ++G+ IT GG++ L    +G
Sbjct: 26542 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26600

Query: 88    TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
              F L IH     D G YTC   N +G+   + +LT++
Sbjct: 26601 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26637



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
             V KP PP G P   D   SS++++W    YDGGS +  Y +EI       W+ +   A  
Sbjct: 15448 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15506

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             ++TS+ +  L  + EYK R+ A+N  G  EP+
Sbjct: 15507 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15538



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W K  K +     MKV   + G               Y +  EN  G  +   +   V  
Sbjct: 19328 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19376

Query: 1331  PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
              DP  P G P  ++I   S++L W    YDGG+ +  Y +E  +  +  W +      + 
Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19436

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
             T F V +L  D  Y+FRV A N     SEPS+ +    V +  E P+  ++V   D
Sbjct: 19437 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19492



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            EK    P F K + + ++  G  A     + G P P++ WF +   +  S  ++  +D D
Sbjct: 3643 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3702

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
             + SLII     +D+ +YTC A N  G+  C+A L + +  EG  + E E
Sbjct: 3703 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3751



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 3/114 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            +E P   P     ++D    EG  ARF C++ G  D +V W+  D+ I+ SR F++   E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME-EGEGEGEEEEE 1863
            D    L I++   +D+  YT  A N++G+ + TA L +E    + +  G++  E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRE 3403



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%)

Query: 405  MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
            ++ + DS     + +P ++   E++ +    EVS         +L+ TPV +   S  V 
Sbjct: 4332 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4391

Query: 465  EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
            ++     L   + +  +S + S T   A  ++      + E   + E  P   + L D  
Sbjct: 4392 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4445

Query: 525  VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580
              EG    L  S+  T    + W    + +   +  +   +     L I     EDH G 
Sbjct: 4446 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4503

Query: 581  YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
            Y C A N  G+ + SA +TV                  K  AP+  + +  L+V  G   
Sbjct: 4504 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4546

Query: 641  TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              T ++   P     W   G EI ES+           SL I      D G YTC+A N 
Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4606

Query: 701  AGEVRTQAVLTVQEP 715
             G V   A LTV  P
Sbjct: 4607 YGSVSCTATLTVTVP 4621



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)

Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
            W     T+K TK  +    EGSL              +++  A+N  GQ++ +    ++D
Sbjct: 7825 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7868

Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
            +  +++T           +  PP      D T +       PPK      I ++  ++K 
Sbjct: 7869 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7919

Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
            R G                  W+K  K      + +V +   G+++      +   G   
Sbjct: 7920 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7960

Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
                  +G       +  ++ P  P   P     +D     + ++W     +GGS +  Y
Sbjct: 7961 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 8014

Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E+     + W  + +   +   F V++ ++PD EY  RVRA+N  G SEPS+ SE   
Sbjct: 8015 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8074

Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
              +   +P  ++E  D    E E     V +R V + T
Sbjct: 8075 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8112



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G+   L+  V   P  TI W    K ++ +    +        + ++ A+  D G Y
Sbjct: 17332 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17391

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
                A N AG       V V D P              P      V G  S+    K    
Sbjct: 17392 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17434

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              +PP       I  +  +++    E+  L   V  ++ +T                    
Sbjct: 17435 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17470

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
               N  K+T L    E+   + ++  NK G  +   +  V+ K     P PP      ++I
Sbjct: 17471 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17525

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
                S+T+ W     DGGS +  Y +E  D +   W +    R T     V  L  DHEY+
Sbjct: 17526 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17585

Query: 1402  FRVRAINVYGTSEPS 1416
             FRV A N  G  EPS
Sbjct: 17586 FRVSAENAAGVGEPS 17600



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E +  +F C ++   +  V W  +G  + +     ++  D   H L +  ++  D G 
Sbjct: 5192 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5248

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+   +  +G+ + +      RL V  +   F S L+D  V EG+     C +    +  
Sbjct: 5249 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5298

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
            + W  N   +  +R+   +   + H  +           + E  L  +S      V E  
Sbjct: 5299 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5346

Query: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
            S+ + + L          P F   L D   ++  ++T+  +VS + P  V W  +G EI 
Sbjct: 5347 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5397

Query: 665  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
             S  +  +  G +  L I++   +D G Y C+     G  +T+A +TV+      +   +
Sbjct: 5398 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5448

Query: 725  SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
             KP   V   +G++      ++    P VH  W   G+ L   +   E++++     L+L
Sbjct: 5449 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5504

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
               Q    G+      N     + +V       +   S  +   +          REP +
Sbjct: 5505 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5564

Query: 828  CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
               L G     +  G DR+  ++ G   +    ++    ED    +    +  +HT    
Sbjct: 5565 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5617

Query: 885  --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
              E IR + +  L  +D+  K+    V T  LS D+++      + +  N QR    ++V
Sbjct: 5618 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5669

Query: 939  S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
            S ++E K HS   + F+  L+   TS+  V                 +  + KL    G 
Sbjct: 5670 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5712

Query: 998  S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
               + +  +   VE  + +   + S    PV   K  + +KP  NA              
Sbjct: 5713 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5759

Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
               +K+  K+    LKK +K+D+       GT     + + +       + L  V V E 
Sbjct: 5760 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5816

Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            +    + ++S D      W L G+ L  T    + +EG + S+ +     +  G
Sbjct: 5817 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5869



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)

Query: 1090  RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
             R E      +   K +DV V   G+  +L+  +   P   ++W+ +GK L+ T   + + 
Sbjct: 18394 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18453

Query: 1148  QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
                   ++ ++  +  D G Y     N  G       V V D P              P 
Sbjct: 18454 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18500

Query: 1208  SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
                  V G  ++        P     A +   II+  E  ++                  
Sbjct: 18501 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18542

Query: 1268  TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               +W +   ++Q   +          K+T L    E+   + ++  NK G  +   +  V
Sbjct: 18543 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18588

Query: 1328  VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
                   KP  P  TP  S I   S+ ++W     DGG+ ++ Y +E  D     W +   
Sbjct: 18589 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18648

Query: 1382  ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
              T       V  L   H Y+FRV A N  G  EPS+ S
Sbjct: 18649 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18686



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
             EAP      +++  K G  A+   ++ G P P + W+R G+ +    ++ +    R T +
Sbjct: 24226 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24284

Query: 91    LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
             L +    +ED G YTC ATN  G  + + +L ++ +     G P+  K  G         
Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24335

Query: 151   TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
                                     G   R      GRP P +TW  G   LQ S  +++ 
Sbjct: 24336 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24373

Query: 211   EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
                    L +  V  +   G Y   + N  G      ++ IQ   D      V E    N
Sbjct: 24374 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24433

Query: 269   SDV 271
             S V
Sbjct: 24434 SAV 24436



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
             +KP  P G P  + +   S  ++W   + DGG+ +++Y +E  +     W  + T   R 
Sbjct: 24518 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24576

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
             T F+V++L+   EY+FRV+  N+ G SE S+ SE       P  PK +V +     KE
Sbjct: 24577 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24627



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
             P FK+ L +    EG+ +  + +VS  PP T+ W  +G+ L     I +  EG    ++ 
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549

Query: 1157  IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
             I   LPED G Y+  A N AG   C   + V+      +  K+ E   R  +  +   L 
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25609

Query: 1215  ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
                   GTES            +A V  KPA  T   K     +I +  E++K+R
Sbjct: 25610 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25664



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
            PYF       ++VEG +  F C++ G P P V W K    +     +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +IS    DD  +YT    N  GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + ++ EN+ G       +  V   +PP+  G    +D+  +S +L W    +DGGS V  
Sbjct: 17882 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17941

Query: 1366  YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             Y +E+     + W  +A  +  +  V  L    EY+FRV+A N  G S+P
Sbjct: 17942 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17991



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)

Query: 1739  EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
             ED  +A L       P    ++P F + + + E  EG +  F+ ++ G P P + W KD 
Sbjct: 25468 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527

Query: 1796  QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
             Q +    + +I ++     +L I D   +D   Y   A N+ G  +C A L VE +   +
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587

Query: 1856  GEGEEEEE 1863
              E + +EE
Sbjct: 25588 QEFKSKEE 25595



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
            P   + ++ + V  G  ARF   I G P P++ W+K++Q +  S  F+  +  DG   +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            ++ +   +D A YTC+A N  G AT +A L VE  E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             V KP PP       D   +S+TL+W    YDGGS +  Y +EI  +  + W+ +      
Sbjct: 17612 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17670

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
             R T F +  L    EYK RV A+N  G  E +  S   TV  KPE+  +  E+  D E
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17724



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)

Query: 1302  QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
             QE C  Y  +L  N+ G    A+    V V +P  P G     D+  ++ T+ W     D
Sbjct: 18958 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 19017

Query: 1359  GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GGS +  Y +E+    ++ W      ++    +  L    EY FRV A+N  G S+P Q
Sbjct: 19018 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 921  EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978
            E+MD  +  Q+ V+P T  E E K + S ++V + +V ++ K    TPV + V     + 
Sbjct: 4334 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392

Query: 979  P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033
                 S+   ++K  + + S + E    K  E+   L   +  GP+   P+ +    E  
Sbjct: 4393 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4450

Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083
                   + NAK             DE  K    +     V + VN +  H G       
Sbjct: 4451 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4509

Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138
                 T  + K +  +  AP  K+K++ + VA G      C++ S P     W   G+ +
Sbjct: 4510 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4569

Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
              +    +     + S+ I +    D G Y C A N+ G   C+  +TV   P  E    
Sbjct: 4570 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4628

Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
              +  R+P+     VL     + ++K+P    PK  PK     +    PE    +  E V
Sbjct: 4629 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4684

Query: 1256 EL 1257
            E+
Sbjct: 4685 EV 4686



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + +   VS  PP T+ W +N +TL     I  +   S  S+ I+      +G+Y
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10288

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
               +AKN+AG+ + +  V V D P    T  P +       S                   
Sbjct: 10289 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10328

Query: 1229  KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
                       ++  F PED                G  PIT  ++  +++        V 
Sbjct: 10329 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10362

Query: 1288  NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
              +      T+    Q     + +  EN +G      + +A V    +  P+ P       
Sbjct: 10363 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10421

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
             ++  +++TL+W    YDGGS + +Y +E      + + ++      S  + V+ L     
Sbjct: 10422 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10481

Query: 1400  YKFRVRAINVYGTSEPS 1416
             Y++RV A+N+ G  +PS
Sbjct: 10482 YEYRVSAVNIVGQGKPS 10498



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + ++  V   P  T+ W    + LK T+ +      +   ++I + +  D G Y   
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A+N  G+      + V D P                   PP    + D            
Sbjct: 14835 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14865

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                 +    + F  D     G        V   Q  + TW++    +       +  +  
Sbjct: 14866 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14914

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
              ++LT     Q     + +  +N+ G      +  +V       P PP GTP  + +   
Sbjct: 14915 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14968

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+SW+    DGGS +  Y +E  +     W+ +  A      F    L     Y+FRV
Sbjct: 14969 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 15028

Query: 1405  RAINVYGTSEPSQESE 1420
              A N+ G S+PS+ SE
Sbjct: 15029 IAENMAGKSKPSKPSE 15044



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)

Query: 1057  ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
             E L   ++ E +   KND        A ++   K  + + TA       Q +    G   
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22360

Query: 1116  LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
              +   +S  P   + W L    LK T  + ++      +++++ ++  D G Y    +N 
Sbjct: 22361 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22420

Query: 1176  AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
             AG    S  V V   P              P +    V    +++ V     PK      
Sbjct: 22421 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +   I++  E                      T  W      ++ ++           K+
Sbjct: 22468 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22497

Query: 1296  TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
             T L    E+   + +  EN+ G S+  +    + + P  P   P   +   + ++++++ 
Sbjct: 22498 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22555

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             W    +DGGS +  Y +E  +     W  +    C   ++ V  L+   EY+FR  A+N 
Sbjct: 22556 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22615

Query: 1410  YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
              G S+ S+ S    + + P +     EV+D
Sbjct: 22616 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22644



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
             P  P   P  +D    S +L+W    YDGG  +  Y +E     ++ W +  T    R T
Sbjct: 14367 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14426

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F V DL    +Y FR+ AIN  G  EP+   ++  V         E E++ D E + E+
Sbjct: 14427 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14477

Query: 1448  DYRTVTINTEQKVSDFYDIEER 1469
               RT+ +     +  F  I+ R
Sbjct: 14478 -RRTLVVRAGLSIRIFVPIKGR 14498



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)

Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
            P      +++E  E ++   A      ++K   KP        + V+EG  ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820

Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
            YP P+V W+ + Q IR+S+ F++ Y  DG   L I D    D  +    A N  G     
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878

Query: 1844 AELIVETMEE 1853
             +L ++  E+
Sbjct: 1879 VKLEIQQRED 1888



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
             GC   + ++ EN+ G  +       V   + P PP       DI  S+++L+W    +DG
Sbjct: 14629 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14687

Query: 1360  GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             GS +  Y IE     +  W  + T +     V++L    EY F+V A+N  G S P +ES
Sbjct: 14688 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14746

Query: 1420  ELTTVGEKPEEPK 1432
                 V E+   P+
Sbjct: 14747 RPVIVKEQTMLPE 14759



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
            AP F Q LQ V V EG     +  +S  P   + W  +G+ + T+    + +S       
Sbjct: 5    APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            ++I      + G Y   A N +GQA  + ++ V    A                      
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP  +Q  +   VR G  V L  +VTG       + + 
Sbjct: 103  ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
              +IQ S   ++    +   L I  A  E  G Y++   N +G   +   L V  + + P
Sbjct: 141  GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200

Query: 1335 A 1335
            A
Sbjct: 201  A 201



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 1754  PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
             P   P+F + +R+L V   S A   CK+ G+P P V W++  +  I +   ++I   + G
Sbjct: 24619 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24678

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                LII+ V  DD   Y  +A N  G  + TA L VE
Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P F    R   + EG    F C+I G P PE+ WFK++  I  S +  I    +   SL 
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26887

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I +    D  KYT KA N  G+ + TA L+V  + E
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
             P PP   P  +D   SS  L W     DGGS V  Y +E  +   + W++      R T 
Sbjct: 10117 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10174

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
               V  L     YKFRVRA+N+ G  EP + +++  + ++   P  +++ S  D
Sbjct: 10175 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10227



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
             KP  P   P   D    +  L W     DGGS +  Y +E        W  +      R 
Sbjct: 11497 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11556

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
              +F V  L+  +EY+FR++A N+ G  EP + +E     +    P+ E++V+  D
Sbjct: 11557 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
             TES   + K    K  P    PP++ +  +++        E  G   +TG      +  +
Sbjct: 12077 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12134

Query: 1269  CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
               W+   K       MKV+N              +H   + +  EN++G  +  +    V
Sbjct: 12135 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12183

Query: 1329  DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
                DP  P G P      D    S+TL W    YDGG+ +  Y +E+       S ++ W
Sbjct: 12184 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243

Query: 1379  KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             K     A      F V  L  + EY+FRV A N  G   P++  E     E  E P+ ++
Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303

Query: 1436  EVS 1438
             + S
Sbjct: 12304 DAS 12306



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
             D+  S++TL+W    YDGGS +  Y +E   +  + W ++ T + T     V  L    +
Sbjct: 23340 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23399

Query: 1400  YKFRVRAINVYGTSEPSQESELTTV 1424
             Y FR+RA N  G SEP +     TV
Sbjct: 23400 YLFRIRAQNEKGVSEPRETVTAVTV 23424



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
             AP F   L++  V    +  L C V G P P + W   G+ I     +Y     + G  +
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I     +D   Y   A N  G VS +A + V                P+K   P  L+
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24727

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
             G+  +  + G  V++ +  SG P P + W   G ++ ++   H++   T+    +  VFP
Sbjct: 24728 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24783

Query: 688   -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
                  +D G Y   A N  G   +     V  V +P  G +   +S+       +  AS 
Sbjct: 24784 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24843

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKA 760
             G S + +  +         WLR G+A
Sbjct: 24844 GGSKITNYIVEKCATTAERWLRVGQA 24869



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
            PDPP        I  +++ LSW     DGGS V  Y +E   WD   +  + W++     
Sbjct: 9707 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9765

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
                 F V+DL+   EY+FRV+A+N  G S+PS      TVG    ++P+ P
Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9812



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
             + G + K    + G P P + W+++ + + +     L C +  T  L    + + DR   
Sbjct: 20580 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20635

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             G Y  +  N  G+   T+ + +        G P+  KT+         E    +W     
Sbjct: 20636 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20687

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
                 K+   +V++ +  R    +      +        +KGN  +            +P 
Sbjct: 20688 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20747

Query: 205   ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
                SV  KN        G+ +   +   +  VV     A   +++S   ++  D  +  +
Sbjct: 20748 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20807

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
              +  K T  D R++VT +              + + C+    G  P        +P    
Sbjct: 20808 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20853

Query: 321   KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
             K     D P    +  +   T SSITL  ++   +      G  V    GEE +      
Sbjct: 20854 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20913

Query: 379   PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
                  T +       PG+     VS    A +  P+E             P+        
Sbjct: 20914 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20973

Query: 422   -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
              S   K  + V+      G P P V W  +     +  GS   Y  E+  S  L  +   
Sbjct: 20974 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 21029

Query: 479   TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
             TR D+G Y  T  N  G+   S T+ V         ++L V  V+    ++L D  +I+G
Sbjct: 21030 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 21088

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
                ++   +      + TW +            +       + D   +    +  LAEN 
Sbjct: 21089 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 21139

Query: 589   LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
             +G                   E   PV  ++  API    + D               DG
Sbjct: 21140 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 21185

Query: 638   SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
               V     V      E  W H G  I ++ +    Q   Q  L  +     + G      
Sbjct: 21186 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21242

Query: 698   WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
               + G +  + ++   E      P        VT  +G +V +     G P P++ WL+D
Sbjct: 21243 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21295

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
             G  L K++      + E+  TL +K  +  H G+Y ++L N V  C   V + +      
Sbjct: 21296 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21352

Query: 818   ALPRG 822
             + P+G
Sbjct: 21353 SKPKG 21357



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)

Query: 1308  YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + +  EN  G  S       T+   P  P GTP   D+   ++TL W     DGGS +  
Sbjct: 21524 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21583

Query: 1366  YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
             YSIE     N+ W      +++ C+   + V  L P   Y+FR+ A N  GT S PSQ S
Sbjct: 21584 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639

Query: 1420  ELTTVGEKPEEP 1431
              +    ++   P
Sbjct: 21640 GIIMTRDENVPP 21651



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)

Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            +EAV  +   VKP F + ++++ + EGS      +  G P+P++VW K+   I   ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557

Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
            I  +   G  +L I      D A YT  A+N  G  T   ++ VE +E  E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)

Query: 388  GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
            G+ + +V  K  + R+ + G R     KF S  + Q VKE +T  F CE+S   K  V W
Sbjct: 5247 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5301

Query: 448  FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
            F     +     ++ +  +  +H L + +    D                        +L
Sbjct: 5302 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5351

Query: 508  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
             V+E  P F+  L D   +E  +  L+C V    VP + W  +G+ I      S    G+
Sbjct: 5352 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5409

Query: 566  AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
               L I+ A  +D G Y C      G     A VTV  +           +   KP    
Sbjct: 5410 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5451

Query: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
                L  ++V  G      +++S  P     W   G  +  S D    + G +H L +  
Sbjct: 5452 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5506

Query: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
                 TG  + +A N+    ++ A L V+E        FI+    V           C +
Sbjct: 5507 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5558

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
            + +P  T  WL+  + +  D   FE++++    ++V+K
Sbjct: 5559 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5594



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
             F+ KL    +  G+   L  + S  P   + W  +    L+  +  I +   +L    I 
Sbjct: 10519 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10574

Query: 1159  KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
             KA   D G Y  V +N  G  +  CQV V D P                   PPV     
Sbjct: 10575 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10616

Query: 1219  DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             D   K        P        I     +K   G+ V +    + +   TC   K  K +
Sbjct: 10617 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10672

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             +  +++   ++EN                Y +       S +A+    V D PD P  T 
Sbjct: 10673 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10717

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
                D    S  ++W    +DGG  + +Y +E  ++ +K W  +        T F V DLL
Sbjct: 10718 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10772

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
                +Y+FRV A N  G  +PS  S+     +   +P   V     D     VD
Sbjct: 10773 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10825



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QL  PV++K L                   PP F        V  G+  +      GRP
Sbjct: 15828 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15870

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
              P VTW K NVPL+ + RV+        +L I    ++DVG Y   + N +G+A
Sbjct: 15871 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 26/77 (33%), Positives = 44/77 (57%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V+ GQ  +    I+GRP+P +TW K  +PL+ + R++V++   +  L I   ++DD G Y
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995

Query: 232   TCLVVNGSGKASMSAEL 248
                V N  G+ + S E+
Sbjct: 16996 GITVANVVGQKTASIEI 17012



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/72 (34%), Positives = 40/72 (55%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G+  +    + GRP+P ++W+K   PL+ + RV+V E     VL I   N+DD G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077

Query: 232   TCLVVNGSGKAS 243
             T    N +G A+
Sbjct: 18078 TVTATNSAGTAT 18089



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
             P F+  + +     G   RF   I  +P+P V W+K  Q I+     + +  + D+ G  
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25443

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              L I+ V  DDDA+YT  A N  GE +C A+L V
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)

Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
            +S +  + A L  V    P +K    + I  LEV  G  A+F C+I+  P+    WFK  
Sbjct: 4511 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4566

Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
            + I ES    I   +  + SL I      D  +YTCKA N  G  +CTA L V T+  GE
Sbjct: 4567 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4624



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G   R    I GRP P+V W K +  ++ +A + V+      VL+   VN+ D G Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16706

Query: 232   TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
             T  + N SG  + SA ++++ LD+ +                                  
Sbjct: 16707 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16764

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
             V + +AT       VTN      K+D L+          A        P +   P   A 
Sbjct: 16765 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16824

Query: 312   SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
               PQPP +  ++    +  +   T       S I      +Q +         R   L  
Sbjct: 16825 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16883

Query: 364   LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
             +  +   GEE          K  + PR    P     + ++D+V +              
Sbjct: 16884 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16924

Query: 412   AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
               P  +    S  V+  Q +K    +SG PKP + W  +G P+ +Q   I V +      
Sbjct: 16925 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16981

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCS 499
             L + +    D G Y  T +N  GQ + S
Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTAS 17009



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E  A E    KP     ++D  V   S A+F  K  G P P  +W KD ++I +   +++
Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
               D+ G   L I      D   YTC   NS G  + + +L ++ +++ E +
Sbjct: 26596 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26645



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R      GRP P++TW +       + +V + +      L I   +++D G
Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17786

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
              Y   + N SG  S SA ++++ LD+         K    +VRK+   ++ +   +D   
Sbjct: 17787 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17838

Query: 290   AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
               AK KN    +R  +    AN   +  + S K+E+  +                     
Sbjct: 17839 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17897

Query: 329   ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
                      P + P    L    +TS+S+  +        R  G  V + P G E K   
Sbjct: 17898 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17956

Query: 376   PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
                         GL S        KA N +         +P+  +  +  P  +    + 
Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 18016

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              ++  + +K    V G P+P ++W  +G P+ +Q   + V E A S  L + +    D G
Sbjct: 18017 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 18075

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
              Y+ TA+N+ G  + + ++ V       V P  F  V  D  VI
Sbjct: 18076 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 18119



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +++K G+  R    + GRP P+VTW K  V ++    + +++  G   L +    +D  G
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21722

Query: 230   VYTCLVVNGSGKASMSAELSIQ 251
             VYT    N SG A    ++ +Q
Sbjct: 21723 VYTVEAKNASGSAKAEIKVKVQ 21744



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P   K ++D+    G AA+  C+I G P P++ W++  + + +SR +++  D   +   +
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +++   +D+  YTC A N +GE   +++L+++
Sbjct: 24288 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24318



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             PT  +       + V  G  V + + ++G PPP   W   G++++ESE    E       
Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
             L I+E    DTG YT E  N  G    T  V+ + +P   T P  I +    S+T S   
Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23550

Query: 735   ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
                 G + L    +         WL   +++ + T  F  L   + +   +     +  G
Sbjct: 23551 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23610

Query: 791   QYEILLKNRVGECSCQVSL 809
              Y   L++ V EC   + +
Sbjct: 23611 SY---LQSEVIECRSSIRI 23626



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
            AP FI  P    + EG +  F  +V G P+P V W ++G P+T+G R+ +    + G   
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
            LVI     +D G+YT    N  G    +  L  E  +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)

Query: 1730  LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
             ++A+  +   D  Q  +  +A++   + P F        V+ G   + D    G P P V
Sbjct: 15816 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15874

Query: 1790  VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              W KD+  ++++     +  E+ N  L I D C +D   Y  K  NS GEA  T  +IV
Sbjct: 15875 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
             K   P TP     PP+    P +       SV L     K  G   +T  +++ ++   +
Sbjct: 24010 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24069

Query: 1281  S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
                 H K + +     +T L    E+   + ++ +N +G S  +  +  VV     DKP 
Sbjct: 24070 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24127

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
              P      S I   S+TL W     DGG  +  Y +E   S +  WK+      +   F 
Sbjct: 24128 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24186

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
             +  LL   EY+FRV A N  G S P     S +++LT+ GE P   K+  +V+
Sbjct: 24187 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24238



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P F+ + ++  V+        C+V+G PKP V W+ +G  +        + E  G ++  
Sbjct: 24623 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24682

Query: 474   LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
             ++ + T D  T Y   A+N  G +S + +L+VE  A + + P     +     + G+   
Sbjct: 24683 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24741

Query: 533   LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
             ++    G P P ITW   GQ +       +  V         P     +D G Y   A+N
Sbjct: 24742 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24800

Query: 588   ALG 590
               G
Sbjct: 24801 RFG 24803



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)

Query: 171   VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V +EG   ++ CKI    Q  QVTW  G   L+ S +  ++ ++G+ +L +  + + D G
Sbjct: 25273 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25332

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
              Y C VVN  G+ S  AEL ++G+      + R T
Sbjct: 25333 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25367



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)

Query: 1105  QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
             ++ H+  G  L L   +   P   + W    +   T   I ++  GS   + I  A  ED
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10978

Query: 1165  RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
              G+Y    +N AG    S +V V D P              P+      +  +S     K
Sbjct: 10979 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 11026

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P                         G SV     V      +  W       ++  H 
Sbjct: 11027 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 11064

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
                 +E    L  +AA            EN+ G          +   DP  P G P    
Sbjct: 11065 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11112

Query: 1342  --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
               D+  + ++L W     DGGS +  Y +E  +   + W +  T  +    V  L     
Sbjct: 11113 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11172

Query: 1400  YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             Y+FRV+A N+ G   P     +    EK   P  E++V
Sbjct: 11173 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11209



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L IK G + + +  V+G P P+VTW ++G  I       +   + G+ SL +     + R
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21721

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
             G YT EA N SG+ +  +++ V+ +  K +G    +   G++ +
Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)

Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
           ++A P F  + QS  V++   V+ +  V+GIP P V ++ +G  + +     ++ ++   
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158

Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
           + L + +A   DSGTYS  A+N+ G+ + +  L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
             W K  K +  + H KV     G               + +  EN  G          +  
Sbjct: 20411 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20459

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
             +D  +PP      +DI  +S++LSW   ++DGGS +  Y +E  D  +  W +       
Sbjct: 20460 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20518

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
              T F +  L  + +Y+FRV A N  G+ S PS+
Sbjct: 20519 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20551



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
            +  P PP   P  +D  S+++ L W   +++GG  +  Y ++        W        +
Sbjct: 8695 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8752

Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               + V+++    +YK RV A+N  G   P  E++  TV E  E P  E++VS
Sbjct: 8753 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8804



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)

Query: 1125  PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
             PP T+ W  + K L +     +    S   ++I +    D G Y    +N  G+ + S  
Sbjct: 20994 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 21053

Query: 1184  QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
              V V D PA+      +  SR   + L  PP++   S   +  ++K+ A K         
Sbjct: 21054 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21105

Query: 1239  QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
                                            TW     +   +    ++ SE        
Sbjct: 21106 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21131

Query: 1299  AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
                      + +L EN++G  +       V   + PA     S  D   +S+ LSW    
Sbjct: 21132 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21182

Query: 1357  YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             +DGGS +  Y +E      +TW      ++    V  L      +FRV A N  G S+P 
Sbjct: 21183 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21242

Query: 1417  QESELTTVGEKPEEPKDEVEVSD 1439
                 + TV E    P  EV++SD
Sbjct: 21243 TIGPI-TVKELIITP--EVDLSD 21262



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
             SE   K+T L    E+   + ++ EN  G   A     L    +P  P G P     +D 
Sbjct: 21903 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21960

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
               ++++L W    +DGG  +  Y IE+  +    W ++    C  T + V DL    EYK
Sbjct: 21961 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 22020

Query: 1402  FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             FRV AIN  G  +  + +      ++   P+ +++ +
Sbjct: 22021 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 22057



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 718   GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
             G  P    + + VT  LG++  +SC I G P P + W R GK L + +  +++  +    
Sbjct: 24225 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24283

Query: 778   TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             TL +   +    G Y  +  N VGE      L+LQ
Sbjct: 24284 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)

Query: 145  SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
            S P  E +     E P  F     L  + VK G        +TG+P+P++TW K ++ L+
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7427

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
               R+++        + I    + D G Y    VN  G+A+   E+++            
Sbjct: 7428 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7487

Query: 253  LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
             D  N S +        D   ++TN + +    DS
Sbjct: 7488 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7522



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
            P PP G P        S+ +SW     +GGS +  Y +E  +  +  W  ++        
Sbjct: 9294 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9352

Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
             +   FNV  LL   +Y+FR  AIN  G   PS+ S+    G+   P  P    EV D
Sbjct: 9353 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9410



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L   V   PP  I W+     L+    + +        +  E     D G Y   
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13462

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G+ E +  V V D P                   PPV  T  + +         P
Sbjct: 13463 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13504

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P       II +   ++       +   K   T    C+   FR          V N E 
Sbjct: 13505 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13547

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
             G               + +  EN+ G          V     P G      +RS   SS 
Sbjct: 13548 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13595

Query: 1349  TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
             ++ W     DGGS +  Y ++     NK W+ +    S  ++ +DL    EY FRV A N
Sbjct: 13596 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13654

Query: 1409  VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
               G   P   SE+T V       +D+V   D D K
Sbjct: 13655 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13680



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             S +  +GQ + I   I+G P PT+ W +DG  L K T    V  + D+ TL +K+     
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16991

Query: 789   AGQYEILLKNRVGECSCQVSLM 810
              GQY I + N VG+ +  + ++
Sbjct: 16992 GGQYGITVANVVGQKTASIEIV 17013



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             VV++     R    I GRP+P+V W K    L   A++ V+  +   +L I  V + D G
Sbjct: 18812 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18869

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
              Y   + N SG  S +A ++++ LDS +      +RE K  +          D   ++TN
Sbjct: 18870 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18927

Query: 278   VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
              I ++ +      A  + NC+         Q G S  +   +  +       E+ +    
Sbjct: 18928 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18987

Query: 331   TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
             + P  P  + T   +T   A ++ E        +  G  V   +    K     +  T  
Sbjct: 18988 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 19047

Query: 384   TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
                 GL  G + V   AA         R    P      E KP  +       VK  + +
Sbjct: 19048 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 19107

Query: 432   KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
             K      G P+  V W  +G  + ++   + V        L + +A   D GTY    SN
Sbjct: 19108 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19166

Query: 492   AQGQLSCSWTLQV 504
             + G ++   T+ V
Sbjct: 19167 SAGSITVPITIIV 19179



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 40/81 (49%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + VK G        + G+P P V+W K    L+P+  + ++ +  +  LE+  VN+ D G
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 13059

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              YT    N SG  S + +L +
Sbjct: 13060 DYTITAENSSGSKSATIKLKV 13080



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)

Query: 1131  WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
             W+  GK ++ +    ++   +   ++I+ A  +D G Y   A N  G      +VTV D 
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167

Query: 1191  PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
             P                   PP     S+ + +K     TPP       I  +  +++  
Sbjct: 14168 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14207

Query: 1251  AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
               E+  L             W    + IQ   H+  +  + G++     +   H G    
Sbjct: 14208 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14248

Query: 1311  LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
                   G       + +VD+  P  P   P  S++  ++ T+SW     DGGS +  Y +
Sbjct: 14249 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14303

Query: 1369  EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
             E  +  +  W        +     V  L     Y+FRV A N  G   PS+ S+   + +
Sbjct: 14304 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14363

Query: 1427  K--PEEPKDEVEVSDDDEK 1443
                P  P     V+D  +K
Sbjct: 14364 AAYPPGPPSNPHVTDTTKK 14382



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)

Query: 12    ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
             I++T++++ P    S P+T   A  +PPR          L +K G     +  V G P P
Sbjct: 12962 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 13020

Query: 63    QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              V+W ++G  +    G +  +    R   +L + +V+ +D G YT  A N SG++  T++
Sbjct: 13021 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13077

Query: 121   LTV 123
             L V
Sbjct: 13078 LKV 13080



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 1325  LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
             +  +D   PP     P  +D   +S++L+W     +GGS V  Y IE+       W +  
Sbjct: 23719 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23776

Query: 1383  TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
              C +T   +++    H     EY+FRV A N  G  EP++      V E  E P  E++
Sbjct: 23777 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23834



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
             + + PS        ++  G+D  ++  V G P P I+W+ +G+P+ Q  R   E  A   
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062

Query: 567   ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
              LHI++   +D G YT  A N+ G  + +  V V EK
Sbjct: 18063 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18099



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QLG PV+++          +E +PS+  E P  F T      VK  +  +      GRP
Sbjct: 19075 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19117

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             Q  V W K    L+ + RV+VS    +  L I   +++DVG Y   V N +G  S++  +
Sbjct: 19118 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19175

Query: 249   SIQGLD 254
             +I  LD
Sbjct: 19176 TIIVLD 19181



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)

Query: 106   CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
             C  TN         ELT +  +  +    V ++   D  S P+  T P I  +   PP+ 
Sbjct: 19429 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19484

Query: 164   ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
                +     +VVK G++ + +  I GRP P ++W K  + ++  AR  +   +   +L +
Sbjct: 19485 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19544

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + D G Y   + N +G  S++    +
Sbjct: 19545 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)

Query: 1700  AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
             AV +  + S M   S +   KS        L++ +  +  ++  A LE  + E+      
Sbjct: 26190 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26249

Query: 1760  FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
                T+        R + V EG +ARF C  +G P P V W +  Q +  S   Q+   + 
Sbjct: 26250 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26308

Query: 1812  GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                +  IS V   D+  Y+    NS G+      L ++
Sbjct: 26309 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
            +++   KP+F K +  L +     A F+C++    DP +V  W  D + +  +   ++  
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +E G CSL        D    TC+A N  G    +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)

Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
            G  P+T  ++  ++++      KV +     + T+    Q     + +   NK G  +  
Sbjct: 7210 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268

Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
                 VN+ T    PDPP       D  ++S+ L+W     DGGS ++ Y +E     + 
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7327

Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             W         T   V  L     Y +RV+A+N  G S+PS+ +E     +  E P+  +
Sbjct: 7328 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7387

Query: 1436 EV 1437
            +V
Sbjct: 7388 DV 7389



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
            K    ++    + G P P+ +W  +G   +  ++G  ++ EDA       S  + + + +
Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
               +G YS TA N  GQ + +  ++V       + L V ++      +       +G D 
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9636

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
                 ++G  + + T  ++G+        C  G     + D L E    +   AEN  G 
Sbjct: 9637 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9687

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                  V   ++ ++R      P+ P  P           +K+  G     TV +S  PP
Sbjct: 9688 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9730

Query: 652  PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
                           + W   G + +     + ++   +    ++++       +  +A 
Sbjct: 9731 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9789

Query: 699  NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
            N+AG  +  A +   +      P  I     +    G +V I   I G PFPT+ W +  
Sbjct: 9790 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9849

Query: 757  ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
                D K       H   L  +D  TLV+ + +    G Y I   N +G  S ++ L
Sbjct: 9850 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9906



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)

Query: 575   PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
             P D   +  +A NA+G +S            S+ S  ++     V P     P +  GL 
Sbjct: 21615 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21664

Query: 631   DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
                +  G  + +   V G P P V W  +G EI++  +          SL +++   +  
Sbjct: 21665 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21721

Query: 691   GTYTCEAWNSAGEVRTQAVLTVQE 714
             G YT EA N++G  + +  + VQ+
Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQD 21745



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
            +++P PP     +SD   SS+ L W     DGGS +  Y IE  +     W    +    
Sbjct: 6984 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 7042

Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
              ++ V  L   ++Y +RV A N  G S+PS+     T  +   EP  ++    D
Sbjct: 7043 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7097



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)

Query: 574   LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
             +P++  T T L E A  Q    A   V+    S  S+ +  +A +  P   + +   S L
Sbjct: 12941 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 13000

Query: 633   KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
              V  G+ V +   V G P P V W  +G  ++ +E     +   Q +LC  E+F    +D
Sbjct: 13001 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 13057

Query: 690   TGTYTCEAWNSAG 702
             +G YT  A NS+G
Sbjct: 13058 SGDYTITAENSSG 13070



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 25/82 (30%), Positives = 36/82 (43%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             + KE    R    I G+P P V+W KG  PL    RVSV        L ++   + D G 
Sbjct: 13688 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13747

Query: 231   YTCLVVNGSGKASMSAELSIQG 252
             YT  + N +G    +  + + G
Sbjct: 13748 YTITLKNVAGTKEGTISIKVVG 13769



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             LT  P+  LP     I+ G   K E  V G P P ++W ++G+P+    R  ++     T
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062

Query: 89    FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               L I   +++D GKYT  ATN +G     + + V
Sbjct: 18063 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
             NA    S    S   +    E  P +  +  +    L +  G + R    ++G P P V 
Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21686

Query: 1791  WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             WFKD   I +  + +I  D  G+ SL + D   D    YT +A N+ G A    ++ V+
Sbjct: 21687 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
             I+ G+    +  V G PEP++ W +  + +    +  L   G R T   VI      D G
Sbjct: 22754 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22811

Query: 103   KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
             KYT    N SG + V+V + V  S     G+  VS+   ++    +S P  +    I   
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22870

Query: 159   CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
                +  T     V+ EG+    S  +T   +      +V  +    P  P     +  +N
Sbjct: 22871 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22930

Query: 214   GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
                +    G+ ++   G    ++     ++    E+S   +D   +  +R T+       
Sbjct: 22931 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22990

Query: 270   -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
              D R +VT+++               + C    R  +   A NS+P     S   SC++ 
Sbjct: 22991 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 23033

Query: 328   ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
                  P +AP+  V+  T  SI+L   +   +     +G +    E+           A 
Sbjct: 23034 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23091

Query: 377   PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
              R   F      +G +     AA   + ++G  + +    E +P                
Sbjct: 23092 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 23148

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
             ++  ++   +++    VSG P P + W  +G  +     S  + +   S+ L ++ K   
Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23204

Query: 480   RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
              D+G Y+  A N  G+ S +  ++V         + V EV+    ++  +   I+G    
Sbjct: 23205 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23260

Query: 533   LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
                   G PV   I          +   T +       I   +      +  L EN  G 
Sbjct: 23261 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23314

Query: 591   --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
                   S  V V E          +P+ P+K            L+V+D ++ T+T  ++ 
Sbjct: 23315 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23350

Query: 649   NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
               P     L++G            + GT+  + +  + P   E T T   E       +R
Sbjct: 23351 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23405

Query: 706   TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
              Q    V EP +      +   R             ++    G+ V +   IAG P P  
Sbjct: 23406 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23465

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              W   G  L +++    V  +  V  L +++      G+Y + LKN  G  S  + +++ 
Sbjct: 23466 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23524

Query: 813   NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
             +               A ++    EP   +    GG    G   ++  + RPGW
Sbjct: 23525 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23574



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
             P PP G P         + + W     DGG+ + +Y ++  +  +  W  +        T
Sbjct: 22935 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22993

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                V  L+   +Y+FRV A+N  G SEPS+ S   +  E    P
Sbjct: 22994 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 23037



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
             V +   S  S++   ++P     +P  E    +   + + I+ GA+ +    V G P P 
Sbjct: 23115 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23172

Query: 64    VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             +TW + G  + S  R ++D        L++  V+  D GKYT EA N SG +  TV + V
Sbjct: 23173 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23229



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)

Query: 988  KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045
            ++++ + +GS   E +    VES   +S  + S       V         K + +A  ++
Sbjct: 4333 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392

Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105
              K   + KP E  + +S E   ++V   V  +    G    +         P     L 
Sbjct: 4393 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4442

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164
            D    EG  + L   +++     + W    K + + +     Q+ +  ++ I+K   ED 
Sbjct: 4443 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4500

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
            +G Y C A ND+G+   S ++TV                                    K
Sbjct: 4501 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4525

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
            + AP    K           E  +V  G   +   ++     +   W K  ++I ES+  
Sbjct: 4526 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4575

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             + +S+  S L IL  +   CG YT    N+ GS      LTV
Sbjct: 4576 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)

Query: 752  VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810
            V+W  + K +  D   F+ LQ+++ +TLV+ KV    H G+Y     N  G+ +    L 
Sbjct: 4464 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4522

Query: 811  LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870
            +   +A  + R  EP    ++  G +           ++R  W   G+  + E D   +R
Sbjct: 4523 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4578

Query: 871  G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917
                     +L+ +V +  ++T +A  +         L      G+K   K L E   K 
Sbjct: 4579 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4636

Query: 918  IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963
             P E++  ++ L++   + +PK   ++  KV  P           ++V+  +V  ++   
Sbjct: 4637 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4694

Query: 964  KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023
            K P P KVP  KPA P           LPA       E   A+      P    +P+   
Sbjct: 4695 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4740

Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083
             PV    P    K    A   E  KP G   P + +   +   ++ + +       G   
Sbjct: 4741 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4795

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137
              +     + +     F ++++D+ + E    G   + +C VS   P+T I  W  +G  
Sbjct: 4796 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4852

Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
            ++ +   +FI   ++  L  + ++ +   D G Y CV +    +   + ++ V++ P
Sbjct: 4853 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4906



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)

Query: 1111  EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
             EG  +   C++ + D    + W    + L+ ++   ++ E  +  + ++     D G Y+
Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25335

Query: 1170  CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
             C   ND G+     ++ V         +  +   RR               T+KK K   
Sbjct: 25336 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25375

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
              T      PP+      ++    GE+V     +T       TW K  ++I+  ++ K   
Sbjct: 25376 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25435

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
              E+ +   +LTI +   +    YT++  NK G    +  LTV   P P            
Sbjct: 25436 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25495

Query: 1335  -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
                     G     +IR S +   TL W     DG       +IEI       +      
Sbjct: 25496 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25546

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
                + +++D LP+    +RV A N  G++      ++  +  K +E K + E     +K+
Sbjct: 25547 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25603

Query: 1445  PEVDYRTVTI 1454
              +   R   I
Sbjct: 25604 IDKTLRMAEI 25613



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+   + +   +G  A FE  V G P P VTW +  + + +   + +     G+ + +
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
            ++    ED G Y C+A N  G      EL V          P  +K+  +          
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3886

Query: 145  SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
              PAVE   S       + AT +   ++K   +   + +++     +   L   +PL   
Sbjct: 3887 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3941

Query: 205  ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
               S+ E++ +          +    + C  +NGS         S  L +Q + S  ++F
Sbjct: 3942 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3990

Query: 261  VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
             +         ET+A  SD  K   + +S E +++SL         + P+ G  P     
Sbjct: 3991 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 4044

Query: 312  SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
            S  +PP  S L S  +    +P+   +  T+    +TLQ    Q
Sbjct: 4045 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4087



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)

Query: 388   GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
             GLG  D         IP+E Q     P  E   +  E   VK   TV+F   + G+P P 
Sbjct: 11184 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11236

Query: 445   VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
               W  +G+ ++  E    V  D  S  L +     RD+G Y  T SNA G  + +  L V
Sbjct: 11237 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             LP      KE +  + +  ++G P P V+W +   P+ +  R  ++     T +L+++  
Sbjct: 13682 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13740

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTVEG 125
              + D GKYT    N +G ++ T+ + V G
Sbjct: 13741 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13769



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)

Query: 1717  SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
             S ++  +  P+ P      E++    E V    + A  +    +K   SK I  L  VVE
Sbjct: 26376 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26435

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
              S  R           EV W+KD + ++E+ HFQ  Y  DG   L I+++   D  +Y C
Sbjct: 26436 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26486

Query: 1832  K 1832
             +
Sbjct: 26487 E 26487



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L+DV+V EG K +L+C+VS     ++ W LN + +K    +    +G+   + I +    
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
            D G YK +     G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            PHV+  F + + DL+V E   ARF+C++    + +V WFKD   I++ + + I   +   
Sbjct: 6067 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6122

Query: 1814 CSLIISDVCGDDDAKYTCK 1832
              L+I+    DD+A+Y+C+
Sbjct: 6123 RILVINKCLLDDEAEYSCE 6141



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
             ++E  P +   L    +  G+   ++  V+G PVPR+TW  +G  I+   +   T   G 
Sbjct: 21652 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21708

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
               L ++DA  +  G YT  A+NA G       V V +
Sbjct: 21709 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21745



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            E  H++  F K I+D++V+E   A F+C++   PD  V W KDDQ ++ +   +I  ++ 
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +  L+I      D  KYT  A    G    TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)

Query: 115  RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
            RQ TV+   EG+  K     V +   G     P  ET+P    E     A +L     G 
Sbjct: 8754 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8808

Query: 170  VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
            + +  G+  R    +TGRP P   W K    L    RV +        L I    + D G
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8867

Query: 230  VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
             Y     N  G    +A           L ++ + +  +  +        D   E+T  I
Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8927

Query: 280  --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
               K++K+ +    +E      + +    G    +   ++ +    PP E       D  
Sbjct: 8928 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8987

Query: 328  SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
             P T+P+     ++T S+ITL       EPR+ G   +     E++R   P         
Sbjct: 8988 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 9043

Query: 382  FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
             PT    + + D         KA N        +P+    Q D   P    +   +  + 
Sbjct: 9044 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 9103

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
            +VK  + V    +V+G+P P++ W    T + +   ++++ ++  S       L + KA 
Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163

Query: 479  TRDSGTYSCTASNAQGQL 496
              D GTY+ TASN  G +
Sbjct: 9164 REDKGTYTVTASNRLGSV 9181



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)

Query: 511   EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
             +V P+FSS     +V  GQD  ++  + G P P ITW  +G P++       T    +  
Sbjct: 16926 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16981

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I++   +D G Y     N +GQ + S  +   +K             P  P  P+   
Sbjct: 16982 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 17028

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPP 651
              +S            ++ +S NPP
Sbjct: 17029 DVS----------AESITLSWNPP 17042



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             +  G  + + + V G P P + W+ +G  ++++   + E+  T   L I+E   +D G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077

Query: 694   TCEAWNSAG-EVRTQAVLTVQEP 715
             T  A NSAG      +V+ +++P
Sbjct: 18078 TVTATNSAGTATENLSVIVLEKP 18100



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +K G   + E  V G P P + W ++G+ +    +  +      T +LV       D G 
Sbjct: 15168 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15226

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
             YT  ATN              G FAK +    V    G      +   V +   +    P
Sbjct: 15227 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15273

Query: 161   P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
             P      K+   +V++ +  R +       + QVT LK    L+ +    RV    K G+
Sbjct: 15274 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15332

Query: 216   -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
                     VL ++     D              +  C     S   S      ++  D A
Sbjct: 15333 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15392

Query: 257   NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
              + +++  K T +D+R +V+ +    E +   +   A   +  SP            +P 
Sbjct: 15393 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15452

Query: 316   PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
             PP   + L++ + S   A   P+    S           PE        P A GL   S 
Sbjct: 15453 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15511

Query: 367   SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
             +          +   +     GLG   +V    KA +R +P E + D+   K  +     
Sbjct: 15512 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15566

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
              ++   T++    + G P PEV W  +       E   +   ++ S Y  L+       D
Sbjct: 15567 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15620

Query: 482   SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
             SG Y  T  N+ G  S    ++V       + L V EV  +  ++  D  +++G   +  
Sbjct: 15621 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15680

Query: 535   CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
               V      R       +      + C     ++   D L E    Y   LAEN  G + 
Sbjct: 15681 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15729

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               A      K S R      P+ P K T            +MD ++   +V +S   P  
Sbjct: 15730 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15768

Query: 654   VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                 H+G           + +G+ + + C      E T T   +    +  V  Q    +
Sbjct: 15769 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15824

Query: 713   QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              +P   + P  I+K             + T   G+ + +     G P P V W +D   L
Sbjct: 15825 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15883

Query: 762   CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
              K T        E+   L +K       G Y + L N  GE
Sbjct: 15884 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15923



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)

Query: 1228  PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
             P  PP A   P++     +   +R  E         G   I   W+  K R  I   +  
Sbjct: 22532 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22586

Query: 1285  KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             KV   E   K+T L    E+    Y L       + +A   +   +  D P G P  +D+
Sbjct: 22587 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22645

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
               S+++L W   +YDGGS V  Y IE   + +  +  W +          F V  L    
Sbjct: 22646 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22705

Query: 1399  EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
              Y+FRV A N  G  S+ S+ +   T  ++   PK E++
Sbjct: 22706 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22744



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)

Query: 656  WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            W+ +G+ I+ES    F   G    L I +V   D G YTC       E  + A L V+E 
Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905

Query: 716  HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
                  +  +    VT   GQ + +SC +  +    V W +DGK + +  G         
Sbjct: 4906 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4960

Query: 776  VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
            +  L +       AG Y + ++N    ECS  V ++
Sbjct: 4961 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4996



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
             P  P G P   D+  S+++L W    +DGGS +  Y +E        W    T       
Sbjct: 12884 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12943

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               +    L    +Y+FR  A      S PS+ S+  T+  +   P+ ++ V+
Sbjct: 12944 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12995



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
             L +K G T +F   +RG P P   W  +G  I +   + ++      FS  L I      
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11271

Query: 100   DRGKYTCEATNGSGARQVTVELTV 123
             D G+Y    +N +G++ V V LTV
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTV 11295



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 601   HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
             +EK  S   +  +PV A      P F    +   V+ G  + + V   G P P V W  +
Sbjct: 15820 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15879

Query: 660   GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
                ++++   + E       L I++   ED G Y  +  NSAGE + T  V+ + +P   
Sbjct: 15880 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15939

Query: 719   TQP 721
             T P
Sbjct: 15940 TGP 15942



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V+V+ G   R    + GRP P+VTW K  +      +  V   + M  L I    +DD G
Sbjct: 12311 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12369

Query: 230   VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
              Y+  +VN +G+ ++   + +      +     S V +T          +D   +VT+ I
Sbjct: 12370 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12429

Query: 280   SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
              ++ + D                                A        P     P  A++
Sbjct: 12430 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12489

Query: 312   --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
               S+P PPR+ ++     +  T    P L+    K    IT      QP  R     V+ 
Sbjct: 12490 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12549

Query: 366   ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
                        G++ K     R A   + P    G      V +A  + +P         
Sbjct: 12550 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12594

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             PK    P+   +K  + ++    V G P P   W  +G         + V++   S  L 
Sbjct: 12595 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12652

Query: 474   LLKARTRDSGTYSCTASNAQG 494
             +     +DSG YS TA N+ G
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 160   PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             PPK      ++ +K G+  R    + G+P P   W KG   +  S+ ++V + +   +L 
Sbjct: 12594 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12652

Query: 220   IHGVNQDDVGVYTCLVVNGSG 240
             I  V + D G Y+    N SG
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)

Query: 4    VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            VK V ++ +SK S +V P    R D  P  +   F+       ++EG       +++G P
Sbjct: 9786 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9839

Query: 61   EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
             P +TW +       N +P+   T   + ++D     T +LVI      D G YT  A N
Sbjct: 9840 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9895

Query: 111  GSGARQVTVELTVEG 125
              G     + L V G
Sbjct: 9896 NLGTASKEMRLNVLG 9910



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)

Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            + +KT++++EV E   A F+C++  +  P  +W K+   I  S  F+I      +  LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
             +   +D A+YT    N    AT T   I+ T    +   EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
            +EV EG+      KI+G P P + WFK      +++   + YD        D  C+L+I 
Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9879

Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
                 D   YT  AVN+LG A+
Sbjct: 9880 QSRRSDTGLYTITAVNNLGTAS 9901



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V+ GQ  R   ++ GRP+P +TW K    L    RV + +      L+I    + D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
              Y     N SG A  SA +++  LD       +  K TN  V KE    IS E+ LD+
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11723



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E V E K  + P        + +  G   R +  + G P P   W K +  +  S H  +
Sbjct: 12583 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12642

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              +  D +  LII DV   D   Y+  A NS G  T   +++V
Sbjct: 12643 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
             NA  + SE   S   + A  E  P    + P +  TI    V  G + + D  I G P P
Sbjct: 16212 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16268

Query: 1788  EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
              + W K DQ +  +   +I    D   SL + D    D   Y  KA N  GE + T  + 
Sbjct: 16269 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16327

Query: 1848  V 1848
             V
Sbjct: 16328 V 16328



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
             P PP      S +   S+TL W     DGGS +  Y IE  +  +  W  +         
Sbjct: 19678 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19736

Query: 1391  VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             V+   L    EY++RV A N  G S PS+ S L
Sbjct: 19737 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19769



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)

Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
            +G    F ++LQD+ V E     L+C VS   P  I   W  N   LK+  K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               +++++    ED+G Y  V                                       
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
              + G ++   +K KP P           I+Q   DQKV  G+ V+L  KV+  + +   
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
            WMK  +++Q S+ + +   +    L I    +E  G Y+  +     S   +V++  VD 
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401

Query: 1331 PDP 1333
              P
Sbjct: 2402 ITP 2404



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)

Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
            F K I+D+ + E    GS+A F+C +   P   +  W KD  +IRES +H  I   +D  
Sbjct: 4812 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +I  DV   D  +YTC       E T TA+L+VE +
Sbjct: 4870 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)

Query: 117   VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
             +  + TV G    Q  +  V++K      S P+  T P    +          PKF    
Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17329

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
               +VV  G+  R    + G+P P + WL+G+  ++ SAR  +   +   +L +    + D
Sbjct: 17330 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17387

Query: 228   VGVYTCLVVNGSGKASMSAELSI 250
              G Y     N +G  S    + +
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKV 17410



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
            +KS  K +++ K + + +N +  H G   +      + T+ A          F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021

Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
             V E K+ + +C+VS +P  T+ W  + + L+ T  I + +E  +  + I      D G 
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080

Query: 1168 YKCVAKNDAGQAE 1180
            Y  VA  +   A+
Sbjct: 3081 YTVVAGGNVSTAK 3093



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             +K G   R S  I G P P+VTW K +      AR+ V+       LEI     +D G+Y
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10982

Query: 232   TCLVVNGSGKASMSAELSI 250
             +  V N +G  ++S ++ +
Sbjct: 10983 SLTVENPAGSKTVSVKVLV 11001



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 21/72 (29%), Positives = 34/72 (47%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++++ G   R    + GRP P++TW K NV L+    + +   +    L    VN+ D G
Sbjct: 13398 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13457

Query: 230   VYTCLVVNGSGK 241
              Y   + N  GK
Sbjct: 13458 KYILTLENSCGK 13469



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + + + V G P P V W      +++++  +FE   T   L I E    D+G Y   
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834

Query: 697   AWNSAGEVRTQAVLTVQ 713
             A N  GEV    V+T+Q
Sbjct: 14835 ARNIVGEVGD--VITIQ 14849



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
             KD  V+  G+ F +   + G P+P I W+   Q +   AR   ++      L ++DA+  
Sbjct: 16245 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16304

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
             D G Y   A+N  G+ S    VTV+ K   R         P  P  P+ + G++  K   
Sbjct: 16305 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16351

Query: 634   -----VMDGSQVTMTVQVSGNPPPEVIW 656
                  + DG    +   V       ++W
Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVW 16379



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 1753  KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
             +P VKP FS       V  G   + +  I G P P + W KD   ++++    +  D   
Sbjct: 16924 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16978

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
               +L I +   DD  +Y     N +G+ T + E++
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 17013



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 736   QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
             + + I     G P  TV+W +DG+ L K+T    V  ++ V +L +K+      G YE+ 
Sbjct: 19105 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19163

Query: 796   LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
             + N  G  +  +++++ +      P   +  SC+ +
Sbjct: 19164 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19199



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
            F + L+D  V EG   +L+C+VS +  A + W  NG + LK+ K+ I++ +G +  + I 
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 6039

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
               PED   Y C    DA   + SC + V
Sbjct: 6040 DCTPEDIKTYTC----DAKDFKTSCNLNV 6064



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            L E   F     N+ + E  T K    V   P  +V W++  + I   GR+ +    R  
Sbjct: 6154 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6212

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              LVI   H ED G Y C   +     +V V                             
Sbjct: 6213 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6243

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
                     E   +F +K   + + EG+   F C I+    P V W + +  L+   +  
Sbjct: 6244 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6293

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            V      +VL +      D+G Y  +V    G A  +A L++
Sbjct: 6294 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6331



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)

Query: 528  GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
            G+   +   V G P+P+I W  N   I+      +             EL I  A+ ED 
Sbjct: 9108 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9167

Query: 579  GTYTCLAENALGQVSCSAWVTVHEKKS 605
            GTYT  A N LG V  +  V V+++ S
Sbjct: 9168 GTYTVTASNRLGSVFRNVHVEVYDRPS 9194



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/93 (27%), Positives = 39/93 (41%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P+  + ++ +  L V  G+ V     + G P P   W  +G+EI+  E +  E       
Sbjct: 11203 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11262

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
             L I+     DTG Y     N+AG       LTV
Sbjct: 11263 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)

Query: 437   VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
             V G P P+V W   G     ++G +++ +     +L +  +   DSG YS T  N  G+ 
Sbjct: 12325 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12382

Query: 497   SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             +    ++V         L V +V  +   V       +G   V    V      R TW  
Sbjct: 12383 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12440

Query: 550   NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
                    +  T E      H+ + +P +   +   A N  G       V     K    S
Sbjct: 12441 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12488

Query: 610   EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
             + L     S+P  P         + ++ +++T         PP    L +G    +    
Sbjct: 12489 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12530

Query: 667   ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
                E+     R T++S+ ++++    TG        +   A N+ G    +    V E  
Sbjct: 12531 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12589

Query: 717   DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
             +   P  I  P  +T   G+ + I   + G P PT  W + G+     + H  V + +  
Sbjct: 12590 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12648

Query: 777   FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
               L++K V    +G Y +  +N  G  + ++ +++ ++     P
Sbjct: 12649 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12692



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T   G +V +   + G P PTV W +DG  L K     ++    ++ TL L  V    +
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 13058

Query: 790   GQYEILLKNRVGECSCQVSL 809
             G Y I  +N  G  S  + L
Sbjct: 13059 GDYTITAENSSGSKSATIKL 13078



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             VV+ G   R      GRP P   W K +  L  S R  +   +    L +   N++D G 
Sbjct: 22063 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22120

Query: 231   YTCLVVNGSGKASMSAELSI 250
             YT  V N SG  S++  + +
Sbjct: 22121 YTLTVENNSGSKSITFTVKV 22140



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
             +  LA+NA G +S  +  T      + + EY    AP K      L G  DL  +  GS 
Sbjct: 22709 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22759

Query: 640   VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             + +   V G P P++IW     E+   E    +  G + +  I+     D+G YT    N
Sbjct: 22760 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22819

Query: 700   SAGEVRTQAVLTVQEPHDGTQP 721
             ++G   T+AV  + +  D   P
Sbjct: 22820 ASG---TKAVSVMVKVLDSPGP 22838



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             T  D ++ P  E    + G+           V ++ G        + G+P+P++ W KG+
Sbjct: 22731 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22780

Query: 199   VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
               L    +VS+          I   ++ D G YT  V N SG  ++S  + +  LDS
Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22835



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
            +N+ + E  TA FE  V  +  P + W +NG  I    +F +   ++G    L+I     
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899

Query: 99   EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
            ED  +YT    N   +  +TV                      E+TV  EG   K L   
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959

Query: 135  VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
            V  K+                      GD     F A    +  +++ E    +F   + 
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019

Query: 169  RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             + V E +   F C+++  P   V W+K +  LQ + R+ + ++  +  L I      D 
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078

Query: 229  GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            G YT +    +G    +A+L ++G D   RS  +E +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V + Q +   CE++   + +V W  +G  V  + G I          L +  A   D+GT
Sbjct: 4919 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4976

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+ T  NA   L CS  ++V    V  +       ++D  V      +  C +     P 
Sbjct: 4977 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 5030

Query: 545  ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
            I W      +  +P        +     L I++A+PED   Y    E         A +T
Sbjct: 5031 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 5086

Query: 600  VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
            + E    R+ E L P+               D+ + +    +   ++S    P   W   
Sbjct: 5087 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 5127

Query: 660  GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
            G  ++ S     +  G +  L + +V  +  G    +A N+     T A+LTV+E     
Sbjct: 5128 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 5179

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
            +  F    + VT    +     C +  +    V W + G  + K +  F+++ +     L
Sbjct: 5180 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5236

Query: 780  VLKKVQPWHAGQY 792
            V+   Q    G Y
Sbjct: 5237 VINDSQFDDEGVY 5249



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F+K + ++EV E    +  C++   P  EV+W+K D+ I E+  ++I   E     L+I 
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6217

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
            +   +D   Y C+  +S  +      EL  E + + +     EGE+ E
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)

Query: 8     ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
             A+  ISK S S  P  + +    E P   + P+    + +  G T + E  V G P P +
Sbjct: 17295 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17352

Query: 65    TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              W R  + I    R    C I+ T     L++      D G+Y   A+N +G++   V +
Sbjct: 17353 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17408

Query: 122   TV 123
              V
Sbjct: 17409 KV 17410



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++VK G     +    GRP P V W K +  L+  A V  ++      L I   N++D G
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19948

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
              YT  + N    AS++  L ++ LD+        T  T  DV KE
Sbjct: 19949 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19987



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +K  ++++ +  V G P P V WF +G  + ++  ++E+ +  GS  L +  A     G 
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21723

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
             Y+  A NA G       ++V+      V P
Sbjct: 21724 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21753



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
             + P       D+ + EG      C   G P PEV W    + I  +E   F I+ + D  
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27080

Query: 1814  CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +LII DV   D   YT    N  G  + T  + + ++
Sbjct: 27081 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 24/96 (25%), Positives = 43/96 (44%)

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
            +C P    +   ++V EG+           P P V+W K    ++ S R+++   +    
Sbjct: 8079 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8138

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
            LE+    + D G+YT  + N  G A+ S  + + GL
Sbjct: 8139 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
            P+      D  VIEG+   +    R  PVP ++W  +G+ ++ + R T +     A L +
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8141

Query: 571  QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              ++  D G YT   EN LG  + S  V V
Sbjct: 8142 PKSVRADAGIYTITLENKLGSATASINVKV 8171



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)

Query: 395   VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
             VSK +    P + QR    P  + K +  EV+E   V    ++ G+P P + WF    P 
Sbjct: 9794  VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9850

Query: 455   RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
             ++ +    V  D   + L     C L   ++R  D+G Y+ TA N  G  S    L V  
Sbjct: 9851  KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9910

Query: 507   LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
                  V P  F SV  D   +       +G   +    +      R TW+ ++ +P    
Sbjct: 9911  RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9966

Query: 558   RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
                C   + +L     L      +  +A+N  G         +  +  + ++ + +P AP
Sbjct: 9967  -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 10015

Query: 618   SKPT 621
              KPT
Sbjct: 10016 DKPT 10019



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)

Query: 1762  KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
             K I  L V  G+  RF   I G P P   W  D   I+   H+ ++ D   +  L I + 
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11268

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIV 1848
                D  +Y     N+ G  T    L V
Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTV 11295



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 23/80 (28%), Positives = 36/80 (45%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G++ ++   I G P P V W +DGK L +     E+       TLV+K       
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471

Query: 790   GQYEILLKNRVGECSCQVSL 809
             GQY + L N  G  S  +++
Sbjct: 18472 GQYILKLSNVGGTKSIPITV 18491



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 26/85 (30%), Positives = 34/85 (40%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L+L   V   P   IIWT   K L   + + L   G   +  I+     D G
Sbjct: 22752 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22811

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y    KN +G    S  V V D+P
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDSP 22836



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)

Query: 604  KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
            K SR +E +  V   + P   + ++ L+ L V  G+++ +   V+G P P++ W      
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +++ +    E    + ++ I +    DTGTY  EA N  G  R  AV+ V
Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7473



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)

Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
            K +  L V  G+       + G P+P++ W K D  +++ +   I+ +     ++ I D 
Sbjct: 7390 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7448

Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
               D   Y  +AVN  G AT   E+ V
Sbjct: 7449 KRSDTGTYIIEAVNVCGRATAVVEVNV 7475



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
            P PP      + I  ++  L W     DGGS + +Y +E  D   K W+ +  T + T  
Sbjct: 7779 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7837

Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
             V  L     Y FRV A N  G S+
Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSD 7862



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P  IL P  + IK G   + E  V G P P   W +    + +     +      +  L+
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12652

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I  V  +D G Y+  A N SG     +++ V
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
             ++  +A N +G +S    L V  +A  + + P+F  +     V+ G+D  +     G P 
Sbjct: 15813 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15871

Query: 543   PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             P +TW  +  P+ Q  R   E+    + L I+DA  ED G Y     N+ G+   +  V 
Sbjct: 15872 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15931

Query: 600   VHEKKSSRKSEYLLPVAPSKPTAPI 624
             V +K             P  PT P+
Sbjct: 15932 VLDK-------------PGPPTGPV 15943



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 20/81 (24%), Positives = 39/81 (48%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV  G+  +    I G+P P + W+KG+  L  +AR+ +   +    L +    + D G
Sbjct: 16248 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16307

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y     N +G+ S++  + +
Sbjct: 16308 NYILKAKNVAGERSVTVNVKV 16328



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             ++ G   K E  + G P+P +TW ++G P+    R  +   +  T +L I   H++D G+
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16994

Query: 104   YTCEATNGSGARQVTVEL 121
             Y     N  G +  ++E+
Sbjct: 16995 YGITVANVVGQKTASIEI 17012



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             ++P          +  G   + +  + G P P + W KD + ++++    ++ +   +  
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 18063

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   DD  KYT  A NS G AT    +IV
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/74 (31%), Positives = 33/74 (44%)

Query: 639   QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
             Q+ + V   G P   V W  +G  ++E+   +     T  SL I+E   ED GTY     
Sbjct: 19106 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19165

Query: 699   NSAGEVRTQAVLTV 712
             NSAG +     + V
Sbjct: 19166 NSAGSITVPITIIV 19179



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 711   TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
             +V EP + T P  +      PR          +    G+ + I+  IAG P P + W +D
Sbjct: 19462 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19521

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             G  + ++    E++  ++   L +K       GQY + LKN  G  S  V+
Sbjct: 19522 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19571



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F+K + D  V EG+ A  +C++    + +V WFK+   I +S+ ++I  D      L+I 
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 6039

Query: 1820 DVCGDDDAKYTCKA 1833
            D   +D   YTC A
Sbjct: 6040 DCTPEDIKTYTCDA 6053



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + ++ G T +   RV+G PEP +TW + G+ +    R  L   +     L I      D 
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11671

Query: 102   GKYTCEATNGSGARQ 116
             GKY   A N SG  Q
Sbjct: 11672 GKYIISAKNSSGHAQ 11686



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V+  QT++    V G P+P++ W  EG  + R E  +++ +D     L + +A   D G 
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11673

Query: 485   YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
             Y  +A N+ G    S  + V       + L V  V     ++  +  +  G   +    V
Sbjct: 11674 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11733

Query: 538   RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
                           +P Q   S   + V +  I+ + L  +   +   AEN +G      
Sbjct: 11734 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11777

Query: 597   WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
               T+  K        +L + P  +P  P       +L + D  +  + ++       G  
Sbjct: 11778 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11825

Query: 651   PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
             P   +  H    ++ S+D+    +G+  +    +          +  +  N  GE   V+
Sbjct: 11826 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11883

Query: 706   TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
             T+ V+  +   D  +P    K   V T   G ++ +   + G PFP V W +D  A    
Sbjct: 11884 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11940

Query: 764   DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              +   ++    D     L K +    G+Y +   N  G
Sbjct: 11941 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11978



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             VK    V     V G P P V+W  +GT ++  EG I++        L L     +DSG 
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 13060

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y+ TA N+ G  S +  L+V
Sbjct: 13061 YTITAENSSGSKSATIKLKV 13080



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)

Query: 490   SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             S++ G ++    +++ R+++    P F   +    V  G+ F L+  V G P+P I WL 
Sbjct: 17303 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17356

Query: 550   NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
               + I+ + + CE       A L ++DA+  D G Y   A N  G  S    V V ++  
Sbjct: 17357 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17413

Query: 606   SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
                        P  P  P+ + G++  K
Sbjct: 17414 -----------PGPPEGPVQVTGVTSEK 17430



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)

Query: 20    DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
             DP+ V    L     E P  IL     R   IK G T +    ++G P P+VTW +  + 
Sbjct: 10894 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10953

Query: 73    ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               +  R  +D    G+   + +A H ED G Y+    N +G++ V+V++ V
Sbjct: 10954 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 11001



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
             VK   T++    V G P PEVAW    + T + R    +++   A S    L KA+  D 
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11966

Query: 483   GTYSCTASNAQGQLSCSWTLQV 504
             G Y  TA+N  G      T+ V
Sbjct: 11967 GKYVVTATNTAGSFVAYATVNV 11988



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)

Query: 598   VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
             V V+EK  S      +P VA      P      S   V  G  + + V +SG P P + W
Sbjct: 16899 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16958

Query: 657   LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
               +G  ++++   +        +L I+E   +D G Y     N  G+   +  ++T+ +P
Sbjct: 16959 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 17018



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
             KD  V+  G+ FVL+  +RG P+P + W  +G+ ++   AR   ++ + +  L ++D + 
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y     N  G  S    V V ++             P  P  P+ + G++
Sbjct: 18469 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18510



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
             Q+  V+   +++      G P P   W     P        +++       L +      
Sbjct: 22060 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 22116

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y+ T  N  G  S ++T++V         +   +V    ++++ D  +++G   + 
Sbjct: 22117 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 22176

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                V      R +W       Q     C   + +++              LAE       
Sbjct: 22177 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22216

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              SA   V+E       E   P+  ++  AP        L V+D S+ +  +         
Sbjct: 22217 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22260

Query: 654   VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
               WL   H+G            Q+  DF  E   T Q +  ++ +  +    +  +A N 
Sbjct: 22261 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22318

Query: 701   AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
             AG    +   +   ++EP  + T        + +T   G    I   I+G P P V W  
Sbjct: 22319 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22378

Query: 757   DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             +   L K+T    +   +D  TL +K      +G+Y + L+N  G  +  V++++     
Sbjct: 22379 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22437

Query: 817   RAL-PRGREPASCED-LCGGGVGADGGGSD 844
                 P      S E  +   G   DGGG++
Sbjct: 22438 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
            G  AKF   ++  P  +  W + G+ I    +    C IR +    SL I      D G+
Sbjct: 4543 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4598

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            YTC+A+N  G+   T  LTV        G+  V K L +R   P  E
Sbjct: 4599 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4641



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
            S +D SQ  +EA+   +E K  V    PYF+  ++D   VE       C+I    D  V 
Sbjct: 5686 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5744

Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            WFKD + I+ S++  I  D      LI+      D  +YTC
Sbjct: 5745 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5784



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)

Query: 21   PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
            PSR    + ++   EAP   L  +    L +K G   +    V G PEP++TW +    +
Sbjct: 7367 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7426

Query: 74   TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                R  ++  +    ++ I      D G Y  EA N  G     VE+ V
Sbjct: 7427 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E + +        +P P V+W  +G  V+  +  + +  D  S +L + K+   D+G 
Sbjct: 8093 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 8151

Query: 485  YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
            Y+ T  N  G  + S  ++V       + +   ++  S   +  +    +G   +L   +
Sbjct: 8152 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8211

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
                  R T++    P+    +     V     +D +P     +   A N +G       
Sbjct: 8212 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8255

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                        E   PV    P  P       D++V + +   MT+  +  PP     L
Sbjct: 8256 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8299

Query: 658  HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
            ++G             +G +    C + + P    TYT +      E    VR +    +
Sbjct: 8300 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8357

Query: 713  QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
             EP   T P     P          S+    G  + +  +I+G P+PT+ W++D
Sbjct: 8358 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8411



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L I+ G      GR  G P+P+V+W ++   +    R  +      T +L        D 
Sbjct: 10523 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10581

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             GKY     N +G+R+   ++ V      + G PV   +    F     +     W     
Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10633

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
                +K+   ++++ ++G+            V     +   + + +VS   +    +  IH
Sbjct: 10634 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682

Query: 222   GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
               N    G+   LV +     SM A+   +  D+ ++  V E    ++        D  K
Sbjct: 10683 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10735

Query: 274   EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
              +TN I ++ +  S   A  +K+                C    R  +        P PP
Sbjct: 10736 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10795

Query: 318   RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
              +   +K    K SP   P+       S  +T Q  R     +  G  V     G+E  R
Sbjct: 10796 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10855

Query: 374   PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
              A   P + P T+    G +D    K     +   G+ D A        K   +P     
Sbjct: 10856 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10915

Query: 421   -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                  + Q +K   T++    + G+P P+V W  E       +  I+V    GS  L + 
Sbjct: 10916 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10972

Query: 476   KARTRDSGTYSCTASNAQGQLSCS 499
              A   D G YS T  N  G  + S
Sbjct: 10973 NAAHEDGGIYSLTVENPAGSKTVS 10996



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 23/81 (28%), Positives = 34/81 (41%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VVK G   RF   I G P P   W      ++     +V   N   VL I    + D G
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11274

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y   V N +G  +++  L++
Sbjct: 11275 EYQITVSNAAGSKTVAVHLTV 11295



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             +++ A + +     +  P  V      EAP   L     + + ++ G +A+     +G P
Sbjct: 17688 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17747

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P++TW R     T   +  ++ G+  T  L I      D GKY  +  N SG++   V 
Sbjct: 17748 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17804

Query: 121   LTV 123
             + V
Sbjct: 17805 VKV 17807



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L L   VS  PP  I W+  G  L +   I  ++  SL  + ++K    D G
Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23208

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y   A+N +G+   +  V V D P
Sbjct: 23209 KYTIEAENQSGKKSATVLVKVYDTP 23233



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
            P F    +SV    G +      I+G P P V W RDG+ +   T    ++  ++    L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
             +  V   ++G+Y +   N  G+ +    L+++  +A        P   + L    +   
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116

Query: 840  GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
             G   R      G P     +    DG +++  L  ++            E         
Sbjct: 117  QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 894  QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
             ++  + +G+  ST  L     +E+PA++     +   Q+     +  E+K+ +    D 
Sbjct: 175  SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231

Query: 954  RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
            RS+    +   G +   +P K PP  P  P  RS     +  K +L  +   S       
Sbjct: 232  RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287

Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
                S  P+ + +   P  PV +  PA
Sbjct: 288  ---HSPSPVRHVRAPTP-SPVRSVSPA 310



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
            E V  + P  KP       D+ V+EG            P P V W KD + ++ S    +
Sbjct: 8071 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8130

Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   +  L +      D   YT    N LG AT +  + V
Sbjct: 8131 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
            SV     ++ G+   +   V G PVP   W      +   R   +     +EL I+DAL 
Sbjct: 8804 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8863

Query: 576  EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
            +DHG Y   A N+ G    +A V V +         +L + P      + L   SD +  
Sbjct: 8864 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8918

Query: 636  DGSQVT 641
             GS++T
Sbjct: 8919 GGSEIT 8924



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
            G  + I   I G P P   W  DGKA    KD  H        E  +N  V  +++ + +
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9577

Query: 786  PWHAGQYEILLKNRVGE--CSCQVSLM 810
              H G+Y I  KN+ G+   +C+V +M
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVM 9604



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)

Query: 668   DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             D HFE  G    H    + +     G ++ E   S G +  +    V  P     P +  
Sbjct: 16190 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16246

Query: 726   KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
                ++    G+S  +   I G P PT+ W++  + L  +T   E+   +   +L +K   
Sbjct: 16247 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16302

Query: 786   PWHAGQYEILLKNRVGECSCQVSL 809
                +G Y +  KN  GE S  V++
Sbjct: 16303 RVDSGNYILKAKNVAGERSVTVNV 16326



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)

Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
            A+E     P     ++D+ V  G  A+F C ++     +V W  +   I ES   ++   
Sbjct: 3481 AKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--RLKQS 3538

Query: 1810 EDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
            ++GN   L I +V   D   Y+C   N  GE T +A L VE   E
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPE 3583



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + V  G  + +  +V G P P++ W   G  +   +     Q   +  L I+E    D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672

Query: 692   TYTCEAWNSAGEVRTQAVLTV 712
              Y   A NS+G  +  A++ V
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV 11693



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             SV A  G+ V +     G P PTV W +D K L  D   + +   +    L + +V    
Sbjct: 20975 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 21033

Query: 789   AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
              G+Y + ++N VGE           SS  ++     PA+C+ L
Sbjct: 21034 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21067



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L+   +G P P I+WL +G P+   ++ R +       L I++A  E  G YT +
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21332

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
              +NA+ +++    V             L P  PSKP  PI
Sbjct: 21333 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21359



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            G E+  T   + PAP   P    PP ++   ++  V  GESV L   ++G    T TW +
Sbjct: 875  GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               QI+ S   ++      ++L I  A  E  G +T    N+ G+      L V
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 614  PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            PV  ++P  P    + +     +++M G  + +   V+G P P  +W     E+ + +  
Sbjct: 8787 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8845

Query: 670  HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
              +  GT+  L I++   +D G Y   A NS G
Sbjct: 8846 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
             L +K G T + E  VRG P P+V W   ++   +T   R  +D     + FSL       
Sbjct: 11906 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11963

Query: 99    EDRGKYTCEATNGSGA 114
              D GKY   ATN +G+
Sbjct: 11964 SDGGKYVVTATNTAGS 11979



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)

Query: 403   IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
             IP EG+ D+   K      +  ++   T++    V G P P++ W      +R + G ++
Sbjct: 13384 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13436

Query: 463   VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
             +       +L        D+G Y  T  N+ G+   +  ++V         + V E++  
Sbjct: 13437 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13496

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
              + V  +  +I+G   ++   V+     R +W         +  T E       + +   
Sbjct: 13497 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13547

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
                  +   AEN  G         + +   +R +     V  S+   P+      DLKV 
Sbjct: 13548 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13588

Query: 636   DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
               S+ + ++   G   P       G+ I     DF  E+   Q    SL +Q    + T 
Sbjct: 13589 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13642

Query: 692   ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
                 T+   A N  GE  T + +TV    D   P    K        A    +  +   I
Sbjct: 13643 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13701

Query: 745   AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
              G P P+V W +    L  DT    V  +    TL++   Q   AG+Y I LKN  G   
Sbjct: 13702 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760

Query: 805   CQVSL 809
               +S+
Sbjct: 13761 GTISI 13765



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             PAF L      +  G   K +    G P P VTWH++  P+    R   +        L 
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15901

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
             I     ED G Y  + TN +G    T+ + V        G   + +   D  +       
Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15956

Query: 153   PSIWGECPPKF 163
                WG  PPK+
Sbjct: 15957 ---WG--PPKY 15962



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD  VV  G   R +  + G P P + W + D+ I ES   +I  + D    LI+ D   
Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17385

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y  +A N  G
Sbjct: 17386 IDGGQYILRASNVAG 17400



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 22/83 (26%), Positives = 37/83 (44%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +  K G        I+GRP P+VTW    + L+ + RVS++       L +    + D G
Sbjct: 22352 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22411

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y   + N +G  + S  + + G
Sbjct: 22412 RYFLTLENTAGVKTFSVTVVVIG 22434



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)

Query: 541  PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
            PV    W+ +N +PI+  +   E GV        +P+        A NA+G         
Sbjct: 8020 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 8063

Query: 600  VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
                + S  SE ++   P  KPT  +      D+ V++G ++++ V     P P V W  
Sbjct: 8064 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117

Query: 659  NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
            +G E++ S+    +       L + +    D G YT    N  G       V  +  P  
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8175

Query: 718  GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
               P    K   +T S       SC +  +P       P +H++ + +   + T +  V+
Sbjct: 8176 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8225

Query: 772  QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              E+  +  +K + P     + +   N+VG
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8255



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 620  PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
            PT  + L    D +KV  G  V +   V+G P P++ W  N   I++  D          
Sbjct: 9090 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9149

Query: 673  QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
            +   +  L I +   ED GTYT  A N  G V
Sbjct: 9150 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9181



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/73 (27%), Positives = 33/73 (45%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V++K G+  R    ++GRP P + W K    L+ +A++ +   +    L      + D G
Sbjct: 15166 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15225

Query: 230   VYTCLVVNGSGKA 242
              YT    N  G A
Sbjct: 15226 AYTLTATNPGGFA 15238



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
             +AP   L P+    + +  G T   E  +RG P P V W ++G+ +  +  R  +   I+
Sbjct: 18398 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18457

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              T +LV+      D G+Y  + +N  G + + + + V
Sbjct: 18458 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18493



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 617   PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
             PS+ T PI ++        + D+K  D      G  + +   ++G P P + W  +G EI
Sbjct: 19466 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19525

Query: 664   QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             +E              L +++    DTG Y     N AG
Sbjct: 19526 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19564



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/83 (24%), Positives = 38/83 (45%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             +  G+ L ++  V   P   + W  +G  ++    + ++      S+ +  A  + RG+Y
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21724

Query: 1169  KCVAKNDAGQAECSCQVTVDDAP 1191
                AKN +G A+   +V V D P
Sbjct: 21725 TVEAKNASGSAKAEIKVKVQDTP 21747



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
            ++++ G   R    + G P P  VW K++  + + R   +  D  G  S LII D    D
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8865

Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
              +Y   A NS G     A + V
Sbjct: 8866 HGRYVITATNSCGSKFAAARVEV 8888



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T  +GQ++ I   + G P P + W ++GK L ++    +++Q+     L +K+      
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11671

Query: 790   GQYEILLKNRVG 801
             G+Y I  KN  G
Sbjct: 11672 GKYIISAKNSSG 11683



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L  +V G P+P ++W  +G   +P +  +   +  +  L +     +D G YT  
Sbjct: 13005 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 13064

Query: 585   AENALGQVSCSAWVTVHEK 603
             AEN+ G  S +  + V +K
Sbjct: 13065 AENSSGSKSATIKLKVLDK 13083



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)

Query: 19    VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
             VDP R+   P  +          + +  G + K +  + G P P + W +  Q +++  R
Sbjct: 16233 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16284

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
               +      T SL +      D G Y  +A N +G R VTV + V        G  V+S 
Sbjct: 16285 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16343

Query: 139   TLGDR 143
                ++
Sbjct: 16344 VTAEK 16348



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
             V+   + +      G P PE+ W        R+EG    +V  + G +Y  L +      
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17783

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y     N+ G  S   T++V       + LAV EV    + ++ +  +I+G   V 
Sbjct: 17784 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17843

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                +      R           YA  + +       +++        +  +AEN  G   
Sbjct: 17844 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17891

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                 V V    + + +E   P  P K T            + D SQ + ++       PE
Sbjct: 17892 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17932

Query: 654   VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
                 H+G           + +GT+         +C   V    +G    +  +A+N  G+
Sbjct: 17933 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17988

Query: 704   VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
                + +       D T QP       + +   G+ + I   + G P P + W++DG+ L 
Sbjct: 17989 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 18047

Query: 763   KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             K T    V +      L +K+      G+Y +   N  G  +  +S+++
Sbjct: 18048 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)

Query: 1740  DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
             D S +    +A+E+   +P F   S+  + L V  G++        G P P V+W K D 
Sbjct: 19862 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19920

Query: 1797  SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
              +R   +       D   SL I +   +D  KYT    N L  A+ T  L+V+ ++
Sbjct: 19921 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19971



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 38    PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
             P   + ++ G+  K +  + G P P+VT  R+G P+ +  RF  +       ++ +    
Sbjct: 20177 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20235

Query: 98    EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
               D G+Y   A N SG  +  + + V        G  V+S
Sbjct: 20236 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G+S+ I   + G P P V W +DG  + K   + E+       +L ++     H G Y +
Sbjct: 21668 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21726

Query: 795   LLKNRVGECSCQVSLMLQNSSARAL 819
               KN  G    ++ + +Q++  + +
Sbjct: 21727 EAKNASGSAKAEIKVKVQDTPGKVV 21751



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)

Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
            +  H G        + +   P      + V V EG+    +C+V+  P   + W LNG+ 
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834

Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
            ++ +K   +  +G +  + I      D G  K  A+N  G  E   ++ +       S  
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893

Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
             +APE    RP+  +      + +     +P   T  K  +  +  +    +KV   ES 
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949

Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
            EL  K          + IT   +K RK+ +  E +                   K   +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009

Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
             G K+TI         L+   E    +  +    +G    A   + VV KPDP       
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063

Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
                       WY +            IE  D     W E   C      ++D+  +   
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101

Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
               V+AIN+ G +        Q  +L T  ++ ++     KD +   + +  EP V  + 
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161

Query: 1452 VTINTEQKVSDFY 1464
                 E    D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)

Query: 935  PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
            P+ V E + K+   Q+ DFRSVL            + P P+   P+F     GK +   +
Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916

Query: 995  NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
                  +T   K V   K             + + K  E  + + +     T +    A 
Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967

Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
                LKS  K+E  +++      +  H     T+ EK++   E + T P FK        
Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027

Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
                    +++Q   V +G     + +V   P     W  NG K  ++ +      E ++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
            C + I     ED       A N AG+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + +   VSG PPP V W  N NE    ++   E      S+ I+       G Y+  
Sbjct: 10234 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10291

Query: 697   AWNSAGEVRTQAVLTV 712
             A N AGE +   ++ V
Sbjct: 10292 AKNEAGERKKTIIVDV 10307



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
             T RD+  V  G   R   +++G P+P++ W K+ +  +RE R   +D  +D     L I 
Sbjct: 11608 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11664

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCTA 1844
             +    D  KY   A NS G A  +A
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSA 11689



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 1749  VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
             V  E+  VK    K + DL+      V  G   R +  + G P PEV W KD  +   +R
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941

Query: 1803  HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               ++  D   + S   ++     D  KY   A N+ G     A + V
Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 22/92 (23%), Positives = 40/92 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G ++ +   V G P P   W    +E+  S      +  +   L I++V  +D+G
Sbjct: 12603 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12662

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
              Y+  A NS+G    +  + V +     QP F
Sbjct: 12663 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12694



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             + +  G + R    I+G P PEV W K D  IR++    +        SL++ +V   D 
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16703

Query: 1827  AKYTCKAVNSLG 1838
              KYT    NS G
Sbjct: 16704 GKYTLTLENSSG 16715



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 1758  PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
             P     +   EVV+   G++ +    I G P P + W+KDD+ ++ +    ++   D   
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20623

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
             S++I D    +   Y  K  N++G A+ T
Sbjct: 20624 SILIKDADRLNSGCYELKLRNAMGSASAT 20652



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V  + G   +    I+G+P P + W K +  LQ +A V V     +  + I   ++ + G
Sbjct: 20577 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20636

Query: 230   VYTCLVVNGSGKASMSAELSIQGLD 254
              Y   + N  G A  SA + +Q LD
Sbjct: 20637 CYELKLRNAMGSA--SATIRVQILD 20659



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)

Query: 143  RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
            RF A   E R  +     PK  T    +VV  G+           P+ +  W K N PL 
Sbjct: 6677 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6736

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + +E+   ++LE     + D G Y  ++ N  GKA     L +
Sbjct: 6737 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6781



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 172  VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
            V+EG       KI G P P +TW K   P +P  +  V   +  N + V     L I   
Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9881

Query: 224  NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
             + D G+YT   VN  G AS    L++ G
Sbjct: 9882 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9910



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
             G    L   ++G P P++TW    +     AR       ++L I++A  ED G Y+   E
Sbjct: 10928 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10987

Query: 587   NALGQVSCSAWVTVHEK 603
             N  G  + S  V V +K
Sbjct: 10988 NPAGSKTVSVKVLVLDK 11004



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
             A+N  G +S  +  T   +    K EY  P     PT          L +  G  + +  
Sbjct: 14045 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14095

Query: 644   VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             + + G P P+  W   G +I+ S+        T   L I+    +D G YT  A N  G 
Sbjct: 14096 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14155

Query: 704   VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
                   +TV +      P  IS   +  A+L
Sbjct: 14156 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14186



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             V  GS + + + +SG P P+V    +G  ++ +  F+ E      ++ ++E    D G Y
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20242

Query: 694   TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
                A NS+G  +    ++ +  P   T P  IS
Sbjct: 20243 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)

Query: 1743  QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
             +AF   + +E P ++P    T    +++    GS    D  I G P P+V W  ++  ++
Sbjct: 22326 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22384

Query: 1800  ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             E+    I   +D   +L + D    D  +Y     N+ G  T +  ++V
Sbjct: 22385 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
            NC+    G  D    N K S      P      + L+DV V  G+     C++S +    
Sbjct: 5862 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5920

Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
            + W L GK L+ +  ++   EG + ++++     ED G  +  AK+
Sbjct: 5921 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5966



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 438   SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
             SG PKP+V+WF +   V  ++    +     +  L  +KA+  DSG Y     N+ G   
Sbjct: 10538 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10596

Query: 498   CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
                 + V       V P SF  V KD  VI
Sbjct: 10597 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10626



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             ++  + G++  +   + G P PT+ WLR  K + +++   E+   +    L++K      
Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17387

Query: 789   AGQYEILLKNRVGECSCQVSL 809
              GQY +   N  G  S  V++
Sbjct: 17388 GGQYILRASNVAGSKSFPVNV 17408



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 161  PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
            P   T L   V +EG +   +  IT   +  V W   N  +    +    +      L I
Sbjct: 4435 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4492

Query: 221  HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
              VN +D  G Y C  +N SGK + SA+L++
Sbjct: 4493 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4523



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
            T S ++  + E    ++  +A N  G  + ++ L V                + D    P
Sbjct: 9046 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9090

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
             ++ R S+ G+           + VK G+       +TG P P++ W K    ++     
Sbjct: 9091 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9140

Query: 205  ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
                +  VS       L I    ++D G YT    N  G    +  + +    S  R+  
Sbjct: 9141 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9200

Query: 261  VRETKA 266
            V + KA
Sbjct: 9201 VTDIKA 9206



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G +V     I G P PT  W  DG  + K   H+ V  +     L +K       G+Y+I
Sbjct: 11220 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278

Query: 795   LLKNRVGECSCQVSL 809
              + N  G  +  V L
Sbjct: 11279 TVSNAAGSKTVAVHL 11293



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
             EAP  +L P     L IK G T       + G P P+ +W + G+ I       +     
Sbjct: 14069 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14128

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              +   + +A  + D G+YT  ATN  G +   V++TV
Sbjct: 14129 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14164



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
             G +  ++  V G P P +TW    Q ++  +       A    L+I + +  D G Y   
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
             A N +G+V     + VH+              P  PT PI
Sbjct: 14835 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14861



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             I+ G + +    ++G P P+V W +    I      ++D     T SLV+  V+  D GK
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16705

Query: 104   YTCEATNGSGARQVTVELTV 123
             YT    N SG +   V + V
Sbjct: 16706 YTLTLENSSGTKSAFVTVRV 16725



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P+  LP     +K     K +   +G P+  V W ++GQ +    R  +    +   SL 
Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19148

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I    +ED G Y    +N +G+  +TV +T+
Sbjct: 19149 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19177



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 1782  EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P V W KD++++     + I+ + D +  L I  V  +D  KY     N +GE
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 21047



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 1084  TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
             +T    ++  +G  P  +    D+ + EGK L + C  + +P   + W+  G+ + + + 
Sbjct: 27010 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27069

Query: 1143  -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
                 +     L ++ I     +D GLY     N+ G    +  + +
Sbjct: 27070 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F + L ++ V+E   + L C+VS  P A +IW    + +  T    +  EG    + I+ 
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6218

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
            A  ED G Y C                                 R P S         +D
Sbjct: 6219 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6237

Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
              VK            +  + I  P++ ++  GE  E    ++  +     W +  K ++
Sbjct: 6238 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6287

Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
              +   V        L +  A  +  G Y ++V    G+ +A  +LTV++K
Sbjct: 6288 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6334



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 16/82 (19%), Positives = 37/82 (45%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             ++ ++ G+    + + +G+P+P+V+W K    +    R  +        LE     + D 
Sbjct: 10522 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10581

Query: 229   GVYTCLVVNGSGKASMSAELSI 250
             G Y  +V N +G      ++++
Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV 10603



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)

Query: 619   KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
             KP   + L G+  L V  G  + +   V G P PEV W    +  ++  S     + R  
Sbjct: 11895 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11952

Query: 677   QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                  + +    D G Y   A N+AG     A + V
Sbjct: 11953 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
             +  +A+NA G +S  +  T      + K E  LP     P      +    + V  G   
Sbjct: 17288 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17338

Query: 641   TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              +   V G P P + WL    EI+ES     +    +  L +++    D G Y   A N 
Sbjct: 17339 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17398

Query: 701   AG 702
             AG
Sbjct: 17399 AG 17400



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + +K G   K    + G P P ++W ++G  I    R  +      T  L +      D 
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19552

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
             G+Y     N +G R V V   V        G   ++    ++ S     P  +    I  
Sbjct: 19553 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19612

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
                 K  T      + EG++   SCK+T         LKGN  +            +P  
Sbjct: 19613 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19665

Query: 206   RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
              V++   +   V      LEI  V ++ + +  C     S   S  +   I+  +  +  
Sbjct: 19666 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19723

Query: 260   FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
             +VR  K    D+R + T +      E ++ +  AA  S     S   R   P +     P
Sbjct: 19724 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19779

Query: 315   QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
              PP + K+ +S K +   A   P+    +          + +       + S  G E   
Sbjct: 19780 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19839

Query: 374   PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
                   A +  R      +G+ D  S +++ +I  E + +  F       ++  VK   +
Sbjct: 19840 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19898

Query: 431   VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
                     G P P V W    T +R +   ++  +   S  L +  A   DSG Y+ T  
Sbjct: 19899 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19955

Query: 491   NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
             N     S +  ++V          +   V K+ AV+
Sbjct: 19956 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19991



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V++G + R +  I G+P P   W K    +   A ++ SE +    L I   ++ D G
Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23898

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y  ++ N  GK ++  ++ + G
Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIG 23921



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
             P  +  +R   V  G   RF   ++  P  EV W+ +   ++ES   +I Y +  G  +L
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26126

Query: 1817  IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              I D   DD   Y     N  GEA+  A L V
Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   + D++V E   A+F+C++   P     W K  Q I     F++  D   + S++I 
Sbjct: 5537 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5594

Query: 1820 DVCGDDDAKYTCKA 1833
                +D+AKY  +A
Sbjct: 5595 SAAFEDEAKYMFEA 5608



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             R+VV  G + R    ++G+P P VTW      L   A +  +  +   V  I    +   
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10285

Query: 229   GVYTCLVVNGSGK 241
             GVY+ L  N +G+
Sbjct: 10286 GVYSLLAKNEAGE 10298



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             ++ G   +    VRG P P+VTW + G    +  G   L+D        LVI     +D 
Sbjct: 12313 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12368

Query: 102   GKYTCEATNGSGARQVTVELTV 123
             GKY+    N +G + V V + V
Sbjct: 12369 GKYSLTLVNPAGEKAVFVNVRV 12390



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             L V  G+    D  + G P P V W KD   ++ +   ++    +  C+L +  V   D 
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058

Query: 1827  AKYTCKAVNSLGEATCTAELIV 1848
               YT  A NS G  + T +L V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 615   VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             VA     AP + L+GL DL  +  + S   + + + G P P V W    + +        
Sbjct: 13667 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13726

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
             E      +L + +    D G YT    N AG +  T ++  V +P   T P
Sbjct: 13727 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13777



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)

Query: 142   DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
             D + AP +   P+I          K G  +V        +  I G+P P+ +W K    +
Sbjct: 14066 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14115

Query: 202   QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             +PS    ++      +L I    + D G YT    N  G
Sbjct: 14116 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G ++ +   I+G P P V   RDG  L K T  F      +  T+ LK+     
Sbjct: 20180 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20238

Query: 789   AGQYEILLKNRVGECSCQVSLML 811
             AG+YEI   N  G     +++++
Sbjct: 20239 AGRYEITAANSSGTTKAFINIVV 20261



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
             V+++   ++ V+K  A   G    L+  + G P P I W  + + +Q     C      +
Sbjct: 20566 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20622

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
             A + I+DA   + G Y     NA+G  S +  V + +K
Sbjct: 20623 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20660



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
            V   P+    W   G PV   +  +   E+ G  Y             Y   A N QG  
Sbjct: 7319 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7365

Query: 497  SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
              S  T +++ +   E    F  V  L    V  G    L  +V G P P+ITW      
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425

Query: 554  I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
            + Q  R T E     + + I D+   D GTY   A N  G+ +    V V +K
Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7478



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 16/67 (23%), Positives = 28/67 (41%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G    +   + G P P + W+    E+  +     +      SL +++    D+G Y  +
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16312

Query: 697   AWNSAGE 703
             A N AGE
Sbjct: 16313 AKNVAGE 16319



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)

Query: 395   VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
             +SK ++   P+  + +   P+    P+ ++   V   +T +   +V G P P + W L G
Sbjct: 17299 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17357

Query: 452   TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
                  +    E+        L +  A   D G Y   ASN  G  S
Sbjct: 17358 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17403



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++  AT +    ++G PEP+V W +    +T   +      +  +F+ LVI  V   D G
Sbjct: 18814 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18869

Query: 103   KYTCEATNGSGARQVTVELTV 123
             +Y     N SG++   V + V
Sbjct: 18870 RYNLTLENNSGSKTAFVNVRV 18890



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             +KP          V      + D   +G P   V W KD Q+++E+    +   +    S
Sbjct: 19088 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19146

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   +D   Y     NS G  T    +IV
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            ++D  V E     F+C++      +  WF+++++I +S  + I   +D   +L I D   
Sbjct: 6341 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6398

Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
            DD A Y     N  GE     A LIVE
Sbjct: 6399 DDQANYNVSLTNHRGENVKSAANLIVE 6425



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 411  SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
            +A PK ++  Q   V   + +         PK E  WF E  P+  +  +I+   +  S 
Sbjct: 6692 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6748

Query: 471  YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
               +L+A+  D G Y     N  G+      L+       V  L V E      S+  + 
Sbjct: 6749 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6807

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLL 549
             + +G   ++   V    + R TW+L
Sbjct: 6808 PLTDGGSKIIGYVVERRDIKRKTWVL 6833



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
            G+  L   S  +K  +S DPS +   PLT   AF+ P  +L   K+G        +    
Sbjct: 7054 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7111

Query: 58   ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
               GYP P  TW    + + +G R  +   +     LVI      D+G YT +  N
Sbjct: 7112 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7166



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
             G + VK G   R    + G+P P+V W K      L  S RV +  +       +    +
Sbjct: 11904 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11963

Query: 226   DDVGVYTCLVVNGSGKASMSAELSI 250
              D G Y     N +G     A +++
Sbjct: 11964 SDGGKYVVTATNTAGSFVAYATVNV 11988



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 1761  SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
             S+  + + V  G +AR     +G P PE+ W +++    +    ++  ++  N + +  D
Sbjct: 17723 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17778

Query: 1821  VCGDDDA-KYTCKAVNSLG 1838
              C  +DA KY  K  NS G
Sbjct: 17779 NCDRNDAGKYILKLENSSG 17797



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)

Query: 21    PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
             P  V    + E P + L  R    + +++G   +    ++G P P   W + GQ I+   
Sbjct: 23817 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23874

Query: 78    RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
             R ++      T  LVI      D G Y     N  G + V +++ V GS
Sbjct: 23875 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23922



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G  + I   ++G P PTV W  + + L ++     +       ++V+K  Q  H 
Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10285

Query: 790   GQYEILLKNRVGE 802
             G Y +L KN  GE
Sbjct: 10286 GVYSLLAKNEAGE 10298



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)

Query: 537   VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             +RG PVP   W  +G  I   ++     +   + L I++ L  D G Y     NA G  +
Sbjct: 11229 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11288

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              +  +TV +              P  PT PI         ++D +   MT  +S  PP +
Sbjct: 11289 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11325



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
             G A R +  + G P P + W KD + +  +   +I    D + +L+  D    D   YT 
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15229

Query: 1832  KAVNSLGEA 1840
              A N  G A
Sbjct: 15230 TATNPGGFA 15238



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)

Query: 20    DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
             +P+ V   P  E    +LPP         + + I+   T +    ++G P P+V W R+ 
Sbjct: 15536 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15593

Query: 71    QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                   G  L    I  T S   L++  V+  D GKY     N SG++   V + V
Sbjct: 15594 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15643



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G  + + V + G P PEV W     EI+++         T  SL +  V   D+G
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16704

Query: 692   TYTCEAWNSAG 702
              YT    NS+G
Sbjct: 16705 KYTLTLENSSG 16715



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)

Query: 17    LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
             +++ P  V  + +T E     +P   + ++ G     E   +G P+P ++W ++G P+  
Sbjct: 21242 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21301

Query: 76    GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                F+         +L I    +E  GKYT    N     ++ V +TV
Sbjct: 21302 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21346



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)

Query: 1745  FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
             + E++AE    ++P     I DLE+ +          G++ R    + G P P + W K 
Sbjct: 23123 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23177

Query: 1795  DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
              Q I  +    ID  E  +  LI+  V   D  KYT +A N  G+ + T
Sbjct: 23178 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23224



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   + D  V EG  A F C++  +    VVWFK+D  +  SR   I   E     L + 
Sbjct: 5271 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5328

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +V  DD ++   +    + E + TA+L V
Sbjct: 5329 EVTLDDISQIKAQ----VKELSSTAQLKV 5353



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   ++D+   E  +A F  ++  + +  V WFK+DQ +  +R   +  DE    S+   
Sbjct: 5626 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5683

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
            D+  DD ++   +A+    EA  T
Sbjct: 5684 DLSIDDTSQIRVEAMGMSSEAKLT 5707



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/72 (27%), Positives = 32/72 (44%)

Query: 185  TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
            TG P+P  TW  G+  L+   RV +   +    L I    + D G+YT  + N     S 
Sbjct: 7114 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173

Query: 245  SAELSIQGLDSA 256
              ++++    SA
Sbjct: 7174 EIDVNVIARPSA 7185



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 10   SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
            S IS+  ++ DP           P   L   ++ + EG         R  P P V+WH++
Sbjct: 8067 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8118

Query: 70   GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
            G+ + +  R  +          V  +V   D G YT    N  G+   ++ + V G
Sbjct: 8119 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8173



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
             G    L+  VRG P P + W  +       RS        A  ++  +  A   D G Y 
Sbjct: 11911 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11970

Query: 583   CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
               A N  G     A V V +K    ++  ++ V+  + T
Sbjct: 11971 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 12009



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 40    RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
             + L ++ G T +    V+G P P++TW +    +    R  LD  I+ T F   +    V
Sbjct: 13396 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13451

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
             ++ D GKY     N  G ++ T+ + V
Sbjct: 13452 NKYDAGKYILTLENSCGKKEYTIVVKV 13478



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             VK V     S  S S DP         E P F +     + L +K GA+       RG P
Sbjct: 19852 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19909

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P V W +    + +  R  +D     T SL I   +  D GKYT    N   A  +T+ 
Sbjct: 19910 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19966

Query: 121   LTV 123
             + V
Sbjct: 19967 VKV 19969



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)

Query: 517   SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
             S + K   V  G  F +    RG PVP + W    +P    R+       +    L I++
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19941

Query: 573   ALPEDHGTYTCLAENALGQVSCSAWVTV 600
             A   D G YT   +N L   S +  V V
Sbjct: 19942 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19969



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             L V  G+  TMTV   G P P V+W     +++     + +   ++ SL I+     D+G
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19948

Query: 692   TYTCEAWN 699
              YT    N
Sbjct: 19949 KYTLTIQN 19956



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G  KL+     +  +LSV+  ++           I   R+L   E     FE  +  +  
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W+   + I    ++ ++   +  + L +  + ++D GKYT  A    G    + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
            TV G          +SK L D+                            V E Q   F 
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C++   P  +  WL+    L  +  +        + L I     DD+G YT  V      
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653

Query: 242  ASMSAE 247
            A +  E
Sbjct: 2654 AKLKVE 2659



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)

Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
            S T  +++E    + ++ +  L+ +++ K  VK              PYF+  + D   V
Sbjct: 5311 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5370

Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            E       C++    D  V WFKD + I  S  + I  D      L I      D  +Y 
Sbjct: 5371 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5427

Query: 1831 CKAVNSLGEATCTAE 1845
            C       +A  T E
Sbjct: 5428 CDCGTDKTKANVTVE 5442



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)

Query: 442  KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
            K EV W L    V  Q    ++  +   H L +   + RD G Y   A + + +      
Sbjct: 6634 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6690

Query: 502  LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
                    +  AP   +  +D  V  G+   +       P     W    +P+       
Sbjct: 6691 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6742

Query: 562  EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
             A      I +A   D G Y  + +N  G+
Sbjct: 6743 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6772



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
            + V  G+ + +   V+  P   I W+ N   + K T  + +++E      +   +SI KA
Sbjct: 9103 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9162

Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
            + ED+G Y   A N  G    +  V V D P+
Sbjct: 9163 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9194



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R+  +  G   R    I+G P P+V W K+D+        +ID    G+  L I +   +
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10977

Query: 1825  DDAKYTCKAVNSLGEATCTAELIV 1848
             D   Y+    N  G  T + +++V
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
             +D  V++ G+   +   + G P+P I+W  +G  I+  R+  E    + H    ++D + 
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19549

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y    +N  G  S +    V +K             P  P  P+ + GL+
Sbjct: 19550 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19591



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++ GA+ +     +G P P   W +    ++       D     +FS L +   +  D G
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22119

Query: 103   KYTCEATNGSGARQVTVELTV 123
             KYT    N SG++ +T  + V
Sbjct: 22120 KYTLTVENNSGSKSITFTVKV 22140



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            + D +V EG   + + K+      E VW KD Q ++ S    I  D+  +  L+I D+  
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373

Query: 1824 DDDAKYTCKAVNSLGEAT 1841
            +D   Y+   + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
            G ++ +   +   P     W  +GK  K  K  +        L    +   + I +    
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
              G Y   AKN AGQ   +C+V V D P
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKVMDVP 9607



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
             GS    D  + G P+P+++W K D+ +       + Y   G  +  +   C   D  KYT
Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22814

Query: 1831  CKAVNSLG 1838
                 N+ G
Sbjct: 22815 LTVKNASG 22822



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
            ++LE++EG  A F C I  E +P   V W +DD+++     + +  D      L++ D  
Sbjct: 6254 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6309

Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   Y    V  +G A   A L V
Sbjct: 6310 LQDMGTY----VVMVGAARAAAHLTV 6331



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 614   PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             P+      AP  + L     L +  G    +T + SG P P+V W  +  ++ E +  H 
Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562

Query: 672   EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
               + T  +L ++++  +  D+G Y     NS G
Sbjct: 10563 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10593



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
             KD  +++ G+ F L+  V G P P + W  +G+ ++   +  E  +A+    L  +D+  
Sbjct: 15163 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15221

Query: 576   EDHGTYTCLAENALG 590
              D G YT  A N  G
Sbjct: 15222 RDSGAYTLTATNPGG 15236



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
             G +  +   + G P+P++T   +G P++          AE   +++++++  D G Y   
Sbjct: 20186 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20245

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
             A N+ G       + V ++             P  PT P+ +  +++  V          
Sbjct: 20246 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20292

Query: 636   DGSQVT 641
              GSQVT
Sbjct: 20293 GGSQVT 20298



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P   + L+    +K   G+ V +   +SG P P + W  +  E+Q +     E      S
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20624

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
             + I++    ++G Y  +  N+ G     A + VQ
Sbjct: 20625 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20656



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             +P + + +  G   +    + G P P  +W   G  +    R  ++   +    L I   
Sbjct: 23438 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23496

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
                D G+YT E  N +G    T+++ +
Sbjct: 23497 TIRDTGEYTLELKNVTGTTSETIKVII 23523



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            F++ ++D+   E  + A F+C+    P  +V W+KD   + E   +++  D   +  L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +   D   Y+C  V      T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)

Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
            W K G  V+        I + S M +I  ++  K   G+ +  + A  L +   VS   +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            + +              ++D+ V+EG+ A  +CK+       V W+ +D+ I+     Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
             ++R L +V  G   R    + G P P+V W K   D  +R+    Q+D   D    L+I 
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12361

Query: 1820  DVCGDDDAKYTCKAVNSLGE 1839
             +   DD  KY+   VN  GE
Sbjct: 12362 NSTRDDSGKYSLTLVNPAGE 12381



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 728   RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
             R++    G S+ I   I G P P V W +D   L K+  + E   N + FT L++ +   
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14534

Query: 787   WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
             +  G++ + ++N  G+ S  V++ + ++    L
Sbjct: 14535 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14567



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             +D+ VV  G     +  I G P P+VVW KD + + E+             +L++ D   
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468

Query: 1824  DDDAKYTCKAVN 1835
              D  +Y  K  N
Sbjct: 18469 TDGGQYILKLSN 18480



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
             K G+    +  + G P P+VTW      +    R  +    +   +L +      D G+Y
Sbjct: 22355 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22413

Query: 105   TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
                  N +G +  +V + V G      G   VS          + E+    WGE      
Sbjct: 22414 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22465

Query: 165   TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
             T++   +V++ + G  + ++      R Q +VT L     ++ S RVS   + G+
Sbjct: 22466 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22518



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 1771  EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
             E S  R    I+G P P V W K +  +       ++     N +LI+ D    D  KYT
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13749

Query: 1831  CKAVNSLG--EATCTAELI 1847
                 N  G  E T + +++
Sbjct: 13750 ITLKNVAGTKEGTISIKVV 13768



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 19/80 (23%), Positives = 30/80 (37%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V   +T     ++ G P P+V W  +G  +      +E+        L +      D G 
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y    SN  G  S   T++V
Sbjct: 18474 YILKLSNVGGTKSIPITVKV 18493



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
             G    +   + G P P+V+W  +G E++E+     E + T  + +L +++    D G Y 
Sbjct: 18417 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475

Query: 695   CEAWNSAG 702
              +  N  G
Sbjct: 18476 LKLSNVGG 18483



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)

Query: 1733 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1779
            E L+  E+  ++  E+  EE   VK             P     + D    EG       
Sbjct: 4397 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4456

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1838
             I      EV W+ +++ +     F+   D++   +L+I  V  +D   +Y C+A+N  G
Sbjct: 4457 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4513

Query: 1839 EATCTAELIV 1848
            +   +A+L V
Sbjct: 4514 KTATSAKLTV 4523



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)

Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
            NC+   + T    K  E    A  F  K Q++ + EG+K    C +S +    + W  + 
Sbjct: 6228 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6283

Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
            KTL++     +  +G    + ++ A  +D G Y  +     G A  +  +TV
Sbjct: 6284 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6331



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R L V  G + R    I+G P PEV W KD+ +++   + +   + +    LII +    
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14535

Query: 1825  DDAKYTCKAVNSLGE 1839
             D  K+     N  G+
Sbjct: 14536 DTGKFVMTIENPAGK 14550



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
             L V  G  + + V + G P PEV W      L N   I+ +E F          L I E 
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14532

Query: 686   FPEDTGTYTCEAWNSAGE 703
                DTG +     N AG+
Sbjct: 14533 NRYDTGKFVMTIENPAGK 14550



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
             G   + +  + G P P V W K DQ +++++  +++++     +++ I++    D   Y 
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14832

Query: 1831  CKAVNSLGE 1839
               A N +GE
Sbjct: 14833 LTARNIVGE 14841



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G++  +   ++G P PT+ W +DGK L + T   E+   +    LV K      
Sbjct: 15165 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15223

Query: 789   AGQYEILLKNRVG 801
             +G Y +   N  G
Sbjct: 15224 SGAYTLTATNPGG 15236



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD+ VV+ G   + +  I G P P + W KD   I E    +I    D +  L + D   
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19549

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y     N  G
Sbjct: 19550 RDTGQYVLTLKNVAG 19564



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 19/71 (26%), Positives = 30/71 (42%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V V+ G   +    I+G+P P+VT  +  VPL+ + R +         + +      D G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240

Query: 230   VYTCLVVNGSG 240
              Y     N SG
Sbjct: 20241 RYEITAANSSG 20251



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
             G++ R     +G P P  VW K D ++      + D     + S +  + C  +DA KYT
Sbjct: 22067 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22122

Query: 1831  CKAVNSLGEATCT 1843
                 N+ G  + T
Sbjct: 22123 LTVENNSGSKSIT 22135



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 525   VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
             V +G    L   ++G P P   W   GQ I + A         EL I++A   D GTY  
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23902

Query: 584   LAENALGQ 591
             + EN  G+
Sbjct: 23903 VLENKCGK 23910


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score =  295 bits (755), Expect = 3e-79
 Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)

Query: 1097  APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
             AP FK++L++++V       L C+V+  P   + W   GK +     K+ I   +G    
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
             + I     +D  +Y+  A N  G    +  + V+                          
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24648

Query: 1215  GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                             P K  +P  +        +R GE V +    +G      TW K 
Sbjct: 24649 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24692

Query: 1275  RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
             +  I  + H +V  + + + L       ++  G Y +  +N+ G  Q  V L V D PDP
Sbjct: 24693 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24752

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
             P G    SD+   S+ L+W   + DGGS + +Y +E   +  + W  +   R T + V +
Sbjct: 24753 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24811

Query: 1394  LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
             L     Y+FRV A N +G S+PS+ SE T   E      +  E  D+     EV     +
Sbjct: 24812 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24868

Query: 1454  INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
              ++ +++ + Y I E LG G+FG V R VE  ++K +  KF K     ++  +++EISI+
Sbjct: 24869 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24927

Query: 1514  NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
             N   H  ++   ++FE    +VM+ E +SG ++FERI    FEL ERE + Y+ Q+ E +
Sbjct: 24928 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24987

Query: 1574  EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
             +++H   I H D++PENI+   +  + IK+I+FG AR+L+   + ++LF  PE+ APEV 
Sbjct: 24988 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25047

Query: 1634  NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
              ++ +  ATDMWS+G + Y+L                                       
Sbjct: 25048 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25107

Query: 1655  ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
                         +R+  ++ LQHPWL +  + +  K +   + ++Y      +K  N V 
Sbjct: 25108 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25166

Query: 1703  AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
             +  R+S    I      +S  G   + +    +E    VS   + AV EE  HVK     
Sbjct: 25167 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25214

Query: 1763  TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
                           + CKIE Y    +V W+   + +  S  ++I Y EDG   L + D+
Sbjct: 25215 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25259

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
                DD  Y CK VN  GE +  AEL V+ + E
Sbjct: 25260 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25291



 Score =  164 bits (416), Expect = 6e-40
 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)

Query: 63    QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
             +VTW+++G+ +   G F       GT+ L I+ + E D+G+Y CE +   G  +  ++  
Sbjct: 26376 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26435

Query: 123   VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
              +            S  K+  Q     T+  +    A E   S      P   T L    
Sbjct: 26436 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26490

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V    + +F+ K TG P+P   W K    +    +  +SE  G   LEIH  +  D G+Y
Sbjct: 26491 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26550

Query: 232   TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
             TC V N +G  S S +L+I+ +       V   K +       + V++E++    +  ++
Sbjct: 26551 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26610

Query: 286   DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
                EA ++         SK   S +   S   +          +K     +  RT  +  
Sbjct: 26611 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26670

Query: 337   VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
                 T  SI  +  R+  +    G         GV   + EE +        T   +Q  
Sbjct: 26671 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26728

Query: 389   LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
                + +   +SK     +  +      +  S  P F S+P+SQ + E Q V F CE+SG 
Sbjct: 26729 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26788

Query: 441   PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
             P PE+ WF    P+     ++ +      + L +  A   DSG Y+  A N +GQ  CS 
Sbjct: 26789 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26845

Query: 501   TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
             T  +  L ++E  PS   VL+        D  LQ S             + Q +Q + S 
Sbjct: 26846 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26887

Query: 561   CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
              EA  +      A       +  ++  ++        ++S S+++ +        S   +
Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 26947

Query: 614   PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
               A  +   P      SD+ + +G  +T+    +G P PEV W   G +I  QE   FH 
Sbjct: 26948 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 27007

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             E      +L I +V  +D G YT    N  G
Sbjct: 27008 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 27038



 Score =  144 bits (364), Expect = 6e-34
 Identities = 102/320 (31%), Positives = 157/320 (49%), Gaps = 23/320 (7%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+   + Q   V+  +  +F   +SG P+P+++W+ E   +       +   D   + L 
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
            L++A   D+  Y+C A N  G  + S +L VE   V+          P+  + L+D    
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311

Query: 527  EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
            EGQ    QC V GT + +++W    +   P ++ R T      +L I +A PED GTYT 
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 584  LAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAPSKPTA---PIFLQGLSDLKV 634
            +A NA+GQVS +A +++       E  S+ +    L V+  K      P F+Q LS L+V
Sbjct: 3371 VASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFPEDTGT 692
             +G  V    +VSG P PE+ W HN   I  ++D  FHFE+      + I + + E  G 
Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490

Query: 693  YTCEAWNSAGEVRTQAVLTV 712
            Y+C+A NSAGE    A LTV
Sbjct: 3491 YSCKAANSAGEATCAATLTV 3510



 Score =  143 bits (360), Expect = 2e-33
 Identities = 126/488 (25%), Positives = 194/488 (39%), Gaps = 100/488 (20%)

Query: 421  QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEG-SIEVYEDAGSHYLCLLKART 479
            Q     E Q  +F+C VSG    +V+W+ +   ++      +  +ED  ++ L + +A  
Sbjct: 3306 QDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFED--TYQLEIAEAYP 3362

Query: 480  RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEV----------------------APSFS 517
             D GTY+  ASNA GQ+S +  L +E  +  E                        PSF 
Sbjct: 3363 EDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFI 3422

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQD 572
              L    V  G+       V G P P I W  N Q I   +          G+A + I D
Sbjct: 3423 QPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVD 3482

Query: 573  ALPEDHGTYTCLAENALGQVSCSAWVTV---------HEK-------------------- 603
            A  E  G Y+C A N+ G+ +C+A +TV         HE+                    
Sbjct: 3483 AYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAE 3542

Query: 604  ---------KSSRKSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMT 643
                     + S+ +E L      PV P+K       T PIF++ +S+  +  G   T++
Sbjct: 3543 EEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3602

Query: 644  VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
            V V G P P++ W  NG  +  S D+ F   G  HSL I     ED G YTC A N  G+
Sbjct: 3603 VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3662

Query: 704  VRTQAVLTVQ---EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCA 743
                A L +    E H  T+                 P F+ + + +  + G   +    
Sbjct: 3663 TICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYT 3722

Query: 744  IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 803
            + G+P PTV W ++ K LC    +  +       T ++   Q   +G Y    +N +GE 
Sbjct: 3723 VVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3782

Query: 804  SCQVSLML 811
            +C   L++
Sbjct: 3783 TCAAELLV 3790



 Score =  139 bits (349), Expect = 3e-32
 Identities = 149/661 (22%), Positives = 246/661 (37%), Gaps = 102/661 (15%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+   VA  + S  +L V+          E P  +   + + ++ G  A+F   + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221

Query: 62   PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P+++W++  Q +++G +  FL D      ++L++     ED   YTCEA N  G    + 
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             L+VE                      P V +        PP   T L   V  EGQ  R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F C+++G    +V+W   +  ++PS    +++      LEI     +D G YT +  N  
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376

Query: 240  GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE---------SKLDSLEA 290
            G+ S +A LS++G          E   +NS     ++    KE           L SL  
Sbjct: 3377 GQVSSTANLSLEGFSKF------EENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430

Query: 291  AAKSKNCSSPQRGGSP----PWAANSQPQPPRESKLESCKDS------------PRTAPQ 334
                      +  G P     W  N Q   P +  +   ++S               A Q
Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490

Query: 335  TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQD 393
                   S+     AA +   P+AP   +     +E +       ++F    + GL S +
Sbjct: 3491 YSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3550

Query: 394  VVSKAANRRIPM-----------EGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPK 442
            +     N  + +           + +++   P F  +  + ++           V GIPK
Sbjct: 3551 LQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPK 3610

Query: 443  PEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
            P++ WF  G  +       +   D   H L +L  +  D G Y+C ASN  G+  CS  L
Sbjct: 3611 PKIQWFFNGV-LLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYL 3669

Query: 503  QVE-----------RLAVME--------VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
            ++              AV +          P F   LK     +G   + + +V G P P
Sbjct: 3670 KINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAP 3729

Query: 544  RITWLLNGQ----PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             +TW    +     + Y       G     + D   ED G Y C AEN LG+ +C+A + 
Sbjct: 3730 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3789

Query: 600  V 600
            V
Sbjct: 3790 V 3790



 Score =  134 bits (336), Expect = 1e-30
 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)

Query: 396   SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
             S    +  P   +  S+ P   +  Q   V  +   KF  + +G P+P   W  +G  + 
Sbjct: 26462 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26521

Query: 456   RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
              Q G  ++ ED G  +L + K  T DSG Y+CT  N+ G +S S  L ++          
Sbjct: 26522 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26570

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
                 +KD    E Q    Q +   TP  +   ++  +  Q A  + E  ++E   Q+ L 
Sbjct: 26571 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26622

Query: 576   -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
              ++  +   ++E      + S   + VHE+  K+S+ SE +   A  K  +       + 
Sbjct: 26623 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26675

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + + +G ++ +   ++G    +V W+ NG E+  SE++ +   G+  +L I++    D G
Sbjct: 26676 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26733

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
               TC +    G V+ Q  LT+ +      P FIS+PRS   + GQ+VL +C I+G+P P 
Sbjct: 26734 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26792

Query: 752   VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             + W ++   +   + +  + ++ +V++L ++      +G+Y I  KN  G+CS   SLM+
Sbjct: 26793 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851

Query: 812   QNSSARALPRGREPA 826
                    LP   EP+
Sbjct: 26852 -------LPLVEEPS 26859



 Score =  122 bits (306), Expect = 3e-27
 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G  + ++  I G PFP   W ++G+ + K      +  +E    LV+K+     +G Y++
Sbjct: 23779 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23835

Query: 795   LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
             +L+N+ G+ +  + + +  S     P G  P   +D+    V       AD GG+D  G 
Sbjct: 23836 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23891

Query: 849   LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
             +          W   +    VRG        +++ E   R     Q      L  +  V+
Sbjct: 23892 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23949

Query: 907   TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
              KT L+  +    P E +D   +       +   +   +V +   ++ +     K    +
Sbjct: 23950 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24008

Query: 964   KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
             KT +   +       PD       + ++ A+N    +ET  A + V    P       G 
Sbjct: 24009 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24064

Query: 1023  LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
             L+ +  +K + TL   KP     K             D   K ++KE +K          
Sbjct: 24065 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24124

Query: 1071  ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
                        +N+    R    T  + K   + G AP  +++++DV    G+   L CQ
Sbjct: 24125 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24183

Query: 1121  VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
             +   P   I W   GK L  ++   +S +G   ++++     ED G+Y C+A N+ G+ E
Sbjct: 24184 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24243

Query: 1181  CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
              S ++ +   P                                    P  P K       
Sbjct: 24244 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24263

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
                 E      G ++ L     G      TW   +K +Q SE++ +EN+E+ + L +   
Sbjct: 24264 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24319

Query: 1300  ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
              R+ H G Y + + N  G+  A +++ + DKPD P G      +  +S  +SW   + DG
Sbjct: 24320 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24379

Query: 1360  GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GS + +Y +E  ++     W+ +++  S T+  + +L  +  Y FRV A N +G S+P +
Sbjct: 24380 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24439

Query: 1418  ESELTTVGEKPEEP 1431
              S +  +    E+P
Sbjct: 24440 VSSVVIIKSPFEKP 24453



 Score =  118 bits (295), Expect = 6e-26
 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)

Query: 621  TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
            T P  + GL ++ V++G  VT+   +SG P P V W     +I+ S DF    +     L
Sbjct: 895  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954

Query: 681  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
             I+E F ED+G +TC A N AG V T   L VQ                           
Sbjct: 955  MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014

Query: 715  ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
                           P +   P+FI+KP       G SV+  C + G+P P V+W + G 
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074

Query: 760  ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             L   TG+ ++V  N+      LV+       AG+Y I+++N+ GE S   SL L+ +  
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131

Query: 817  RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
              L + ++    +      V        + G   PG+  +  +   E+E     + + K 
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186

Query: 876  RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
             V  R + E+    QE     F + L K++     KT  E+ L+E   E+M    +    
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242

Query: 933  VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
            V+    S  + ++ + + ++   V      S  P+P        +++   +    DF   
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298

Query: 982  -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
             R+ L     LP + G  +A   N K         NA  SG     P  P+G      TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350

Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
            +P+   +   +L P   ++    +  A     +         +       +    S+ + 
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407

Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
               P F  K       EG+      +V   P     W  +G+ +    T  +++ ++G+ 
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
             S+ I  A P D G +  VA+N AG++  S  +TV+                        
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504

Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
                                +  + P  ++  ++  ++ G  +E+  + TG       W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544

Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
            K    I   ++  +++E ++  + L I +   +    YT    NK G  + + +VN+ V 
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
              +P+P      P GT  A +I +  L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631



 Score =  115 bits (288), Expect = 4e-25
 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
             + E Q +  +  ++G    +V W L G  +   E     Y  +GS     +K A  RD G
Sbjct: 26678 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26733

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
               +C +   +G + C + L + +   +  AP+F S  +   + EGQ+ +  C + G P P
Sbjct: 26734 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26791

Query: 544   RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              I W  N  PI  + +        V  L I++A   D G YT  A+N  GQ S +A + V
Sbjct: 26792 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851

Query: 601   HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                         LP+   +P+  + L+   D   + GS  + +VQ+S +         + 
Sbjct: 26852 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26897

Query: 661   NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
             +      +  F     Q    +QE F E + +      N   ++ +     ++    G  
Sbjct: 26898 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 26956

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
             P   + P  ++   G+ + ++CA  G+P P V W   G+ +  ++ G F +   +D+ TL
Sbjct: 26957 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 27016

Query: 780   VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
             ++  VQ    G Y + L N  G  S  V++ +++
Sbjct: 27017 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27050



 Score =  115 bits (287), Expect = 5e-25
 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)

Query: 163  FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
            F +++    + EG    F CK++G P P++ W K         R+   E+  M  L+   
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297

Query: 223  VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
                             G+AS+   + +   +    +F    K           N I   
Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330

Query: 283  SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
             KL  +E AA           G+P +    +P     S++ S   SPR+  ++P+     
Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369

Query: 343  SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
                    R+ P   +P           R  PA   PA      PG   ++       R 
Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
                       P F  KP S +  E QT +F  +V G P PE  WF +G  +        
Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V ++ G+  L ++ A   DSG ++  A N  G+ S S  L VE +   +V P F   LK+
Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
              + EG    ++    G P P I WL N     P +Y +   E   G A L I   + +D
Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578

Query: 578  HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
               YT  A N  G+    C   V V   +   + + ++P          AP         
Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638

Query: 618  -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
                          K   P F + L+ L++          +++  G+P   V WLH+G  
Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
            ++ +            SL     +  D+G  TC A N  G   T A L V++        
Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758

Query: 715  ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
                               H+G             +P  +  P  V    G++    C +
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
             G P P V+W  +G+ L + +  F V + + +  L +   + +  G+ ++  +N  G   
Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876

Query: 805  CQVSLMLQNSS--ARALPRGREP 825
             +V L +Q        L R  EP
Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899



 Score =  113 bits (282), Expect = 2e-24
 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             +K S RK E L     +   AP     +   +V  G      + V   P  EV W HNG 
Sbjct: 25981 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26040

Query: 662   EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
             E+QES                 D H +  GT  ++C                        
Sbjct: 26041 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26100

Query: 683   ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
                      + VFPE T T              EA +S  EV++Q   T +      H  
Sbjct: 26101 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26160

Query: 719   TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
             +                              ++KPRS+T   G+S   SC   G+P PTV
Sbjct: 26161 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              WLR G+ L     H +V   +   T  +  VQ    G Y ++++N  G+   + +L +Q
Sbjct: 26221 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279

Query: 813   NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
              +                        + ++  R + P                 +++   
Sbjct: 26280 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26339

Query: 849   LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
             L    P +   +L+ E  +++          VL+ +  T     + +++    Q  +   
Sbjct: 26340 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399

Query: 901   LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
                ++    L+E D    + EI  E    + NLQ   +  K++ E+  K+   ++ D + 
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459

Query: 955   --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
               S + +K   K P P    P                          P+P    T D ++
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519

Query: 984   VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
             +  GGK KL  + G                            SS+  L  KA++ ++   
Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26579

Query: 1016  -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
              + Q +  + P   A   E +     A  +E +K M  AK  E L   + ASK    EE+
Sbjct: 26580 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26636

Query: 1068  KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
             KK     +     H   T   + SE   T    K     + + EG++L+L+  ++     
Sbjct: 26637 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26694

Query: 1128  TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
              + W LNG  L  ++       GS  +++I++A   D G+  C++K   G  +C   +T+
Sbjct: 26695 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754

Query: 1188  DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
                       + E+                SDA                 P  I  P  Q
Sbjct: 26755 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26771

Query: 1248  KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
              +  G++V    +++G       W K    I  S ++ +  S N   L I  A     G 
Sbjct: 26772 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26831

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+  +N  G   A  +L V+   + P+          +SL  S+   S    ++ Q  S
Sbjct: 26832 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26891

Query: 1368  IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
                + S++ +   +   +  S + Q +    E    + + +  G S  +Q     S++  
Sbjct: 26892 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26949

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEV 1447
              G +   PK E   SD    E +V
Sbjct: 26950 AGIRGIPPKIEALPSDISIDEGKV 26973



 Score =  112 bits (279), Expect = 4e-24
 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
            +N  I EG    F  ++ GYP P++ W+++G+ I  G R+ +D    G  SL I  V  E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311

Query: 100  DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
            D G YT  A+N  G    + +L VE   A  LG P    TL      R  +P   +R  I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369

Query: 156  WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
                                                     P F  K       EGQ  R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429

Query: 180  FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
            F  K+ GRP P+  W   G   +       V +++G Q L I      D G +T +  N 
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489

Query: 239  SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
            +G++S+S  L+++ ++      FV + K  N          I + S+L+    A  + N 
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538

Query: 298  SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
                      W  NS    P    + ++E  K        + V Q               
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592

Query: 340  -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
              T   + ++    +PEP      ++ P G  R K  A P   P      Q      D+ 
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
             K   ++           P F+ K  S  +K      F C ++  G P   V W  +G P
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698

Query: 454  VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
            +      + +  + G   L    A +RDSG  +C A+N  G    S TL           
Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757

Query: 503  -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
                       ++E L  M    + + V  D                 V+EG+    +C 
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817

Query: 537  VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
            V G P P++ W LNGQ I+ ++       G+  L I D    D G     AEN  G +  
Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877

Query: 595  SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               + + +++  R    +L  AP  +P   +   G    +V    +   T +       E
Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929

Query: 654  VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
            V+ L     I      +ESE+    F++R  +            S    E + E      
Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
             E  +   E+  +    + E    T P F                  + +S T   G   
Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049

Query: 739  LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
                 + G P P   W ++G  + +    +     ++V  LV++ V    +    +   N
Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109

Query: 799  RVGECSCQVSLMLQ 812
              GE S    L++Q
Sbjct: 2110 IAGETSSHAFLLVQ 2123



 Score =  111 bits (278), Expect = 6e-24
 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +PP+I+  PE   ++AG+ + +   V G    TC W K   ++  S H+ V  +++ S L
Sbjct: 12526 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12584

Query: 1296  TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
              I    ++  G Y+L  EN  G+   ++ + V+D P PP      SDI + + +LSW+  
Sbjct: 12585 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12644

Query: 1356  SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
               DGGS + +Y +E  D +   W   LA+   TS  V  L+P  EY FRVRA N +G SE
Sbjct: 12645 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12704

Query: 1415  PSQESELTTVGE--KPEEPKD 1433
             P    ++        P EPK+
Sbjct: 12705 PLTSPKMVAQFPFGVPSEPKN 12725



 Score =  110 bits (275), Expect = 1e-23
 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)

Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
           AP+F+  L+   V+EG     +  + G PVP ++W  +GQ I  +     + +   G A+
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
           L I      + G Y+  A N  GQ + +A + V       K+E     AP     P F+Q
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108

Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
            L  + V  GSQV + V+V+G P P V +  +G EIQ S DF   Q G  +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168

Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
           ED+GTY+  A NS G   + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194



 Score =  109 bits (272), Expect = 3e-23
 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)

Query: 30  TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
           T+AP F  P +++ + EG+TA FE  + G+P P+V+W R+GQ I++        G++ +F
Sbjct: 3   TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58

Query: 90  S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
           S     L I AV + + G+Y+ +ATNGSG    T EL V+   A                
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102

Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
                          PP F  +L  + V++G   R   ++TG P P V + +    +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147

Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
               +S++  +  L I     +D G Y+    N  G+A+ +AEL +QG            
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207

Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
           + +A  S  R+T+     +   +  ++ + E  +D   AA +     +P R   PP   +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263

Query: 312 SQPQPP 317
             P PP
Sbjct: 264 RSPTPP 269



 Score =  109 bits (272), Expect = 3e-23
 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)

Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
            V+AG  +EL   VTG      TW K    +++ + + +EN    S +TI+ +++   G Y
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7389

Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             +   N  G   A V + V+DKP PPA     +D+ + S  L+W     DGGS + +Y +
Sbjct: 7390 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7448

Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
            E   + ++ W +L +T + T+F    L+P+ EY FRV A N+YG  EP Q S +T   + 
Sbjct: 7449 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7508

Query: 1427 KPEEPKDEVEVSD 1439
             P  P   +E SD
Sbjct: 7509 DPPGPPTRLEPSD 7521



 Score =  106 bits (264), Expect = 2e-22
 Identities = 102/414 (24%), Positives = 158/414 (38%), Gaps = 48/414 (11%)

Query: 415  KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            +F    +  +V E +   F CEVS  P   V W  +   ++  +  I++ ++   H L +
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
               R  D+G Y+  A            +   +L V        S+ K+  VIE Q  V++
Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121

Query: 535  CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
              V    V    W  +G  I +      +   E  +  + I +    D G YT +A    
Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
                            +R S  L   AP  P     LQ L  + V  G        +SG 
Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P P++ W      +       F   G +++L + E FPED   YTCEA N  G   T A 
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 710  LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            L+V+ P     D   P +    I+  +    S GQ     C ++G       + +D K  
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337

Query: 762  CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815
             K +  F + Q ED + L + +  P   G Y  +  N VG+ S   +L L+  S
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFS 3391



 Score =  102 bits (253), Expect = 5e-21
 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             +++ E  K RAG SV+L   ++G    T  W K  K++Q +  + VEN+ + + + I  A
Sbjct: 20504 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20563

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              + + GCY L + N +GS  A + + ++DKP PP G      + +  +TL W   + DGG
Sbjct: 20564 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20623

Query: 1361  SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             + +  Y +E  +++   W    + L  C  T+  +   +  +EY FRVRA+N YG  EP 
Sbjct: 20624 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20680

Query: 1417  QESEL 1421
             +   +
Sbjct: 20681 ESDSV 20685



 Score =  101 bits (252), Expect = 6e-21
 Identities = 114/459 (24%), Positives = 183/459 (39%), Gaps = 56/459 (12%)

Query: 384  TRQPGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP 441
            TR    G   VV+    +  ++ +EG RD      + + Q  E K+   V+F      + 
Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAKLFVEG-RDVRIRSIKKEVQVIE-KQRAVVEFEVNEDDV- 3129

Query: 442  KPEVAWFLEGTPVRRQEGSIEVYE-DAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
              +  W+ +G  +  Q      Y  +   H + + + R  D+G Y+  A    G+   S 
Sbjct: 3130 --DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSV 3183

Query: 501  TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--- 557
            TL V         P     L+   V  G+       + G P P+I+W    Q +      
Sbjct: 3184 TLYVNA----PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239

Query: 558  RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
            +   +     L + +A PED   YTC A+N  G  + SA ++V E       +  +PV P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMPVYP 3298

Query: 618  SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677
                 P  +  L D    +G       +VSG    +V W     +I+ S  F   Q    
Sbjct: 3299 -----PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDT 3352

Query: 678  HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ------------------------ 713
            + L I E +PED GTYT  A N+ G+V + A L+++                        
Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKK 3412

Query: 714  EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKD-TGHFEV 770
            EP  G +P FI    S+    G++V     ++G P P + W  + + +   KD   HFE 
Sbjct: 3413 EPL-GQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE- 3470

Query: 771  LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
             ++  +  +++      HAGQY     N  GE +C  +L
Sbjct: 3471 -ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATL 3508



 Score =  101 bits (252), Expect = 6e-21
 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)

Query: 1236  MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
             +PP +   ++  E   V+AG +V     + G    T  W     +I+  EH  VE     
Sbjct: 11134 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11193

Query: 1293  SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
             S LTI    +   G Y + V N  GS+   V+LTV+D P PP G     D+    +T+SW
Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11253

Query: 1353  YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
                  DGGS V +Y +E  D+   TW  +++  S T   +  L    EY FRVRA N  G
Sbjct: 11254 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11313

Query: 1412  TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
                P  +S  T    K  P  P  +  V+D  E    V +     +    ++ +Y +E R
Sbjct: 11314 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11371

Query: 1470  LGSGKFGQV 1478
               +GK+ +V
Sbjct: 11372 EVTGKWVRV 11380



 Score =  101 bits (252), Expect = 6e-21
 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+ +M P+   + +   V AGES ++   + G    T  W+K  +++  +  +++++++
Sbjct: 16168 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16224

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L++  A +   G Y L  +N  G R   VN+ V+D+P PP G    S + +   TL
Sbjct: 16225 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16284

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGGS + +Y +E  +++   W  + A  ++ S  V  LL  +EY FR+ A+N 
Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16344

Query: 1410  YGTSEPSQESELTTVGE--KPEEPK 1432
             YG  EP +   +        P+ PK
Sbjct: 16345 YGVGEPLESEPVVAKNPFVVPDAPK 16369



 Score =  101 bits (251), Expect = 8e-21
 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)

Query: 1243  FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
             F +   VRAG S+ LF    G    T  W K    +  S    +  +++ S LT+    +
Sbjct: 21991 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22048

Query: 1303  EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
                G YTL VEN  GS+     + V+D P PP G     D+   S TL W     DGG+ 
Sbjct: 22049 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22107

Query: 1363  VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             +  Y +E  +++ ++W+ ++  C    F V DL     Y FRV A+N YG  EP +  E 
Sbjct: 22108 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22167

Query: 1422  TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
                 E+P  P+  D V+ S         +P+ D         +   QK SDF+ +E    
Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22226

Query: 1472  SGKFGQVFRLVEK 1484
                   V RLVEK
Sbjct: 22227 KQLTFTVERLVEK 22239



 Score =  100 bits (250), Expect = 1e-20
 Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%)

Query: 63   QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
            +V W+   + + S  +F  L D   + T++LVI  V+ ED +G+Y CEA N SG    + 
Sbjct: 4396 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4452

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
            +LTV    A     PV+ +                           K+  + V  G + +
Sbjct: 4453 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4480

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F+C+I   P  +  W K    +  S + S+     +  LEI      D G YTC   N  
Sbjct: 4481 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4540

Query: 240  GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
            G  S +A L  ++ G +   R  + E K    + ++EV   +V+ K  + +  +   K  
Sbjct: 4541 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4597

Query: 295  KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
            +    P     PP      P+P  E ++ +     R  P+   + +   +I L A   +P
Sbjct: 4598 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4651

Query: 355  EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
            +P A    +  P  E    P    P T P       ++    +AA  + P++G       
Sbjct: 4652 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4710

Query: 415  KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441
              E+     +P S   K      F  ++  +P                            
Sbjct: 4711 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4770

Query: 442  KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
             P  A   W  +G+ + R+        D     L ++  +  D+G Y+C       + + 
Sbjct: 4771 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4829

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
            +  L VE L V  V     ++ ++  V++GQ   L C +       + W  +G+ +    
Sbjct: 4830 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4883

Query: 559  STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
                 GV      L I DA   D GTYT   ENA   + CS+ V V E
Sbjct: 4884 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4930



 Score =  100 bits (250), Expect = 1e-20
 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             ++F +   ++AGE+  L   V+G  P T  W K  K+++ +  ++++ ++  + L    +
Sbjct: 15093 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15152

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              +   G YTL   N  G  +   N+ V+D+P PP G    +++ S    LSW+    DGG
Sbjct: 15153 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15212

Query: 1361  SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             + +  Y ++  +++   W  +A+  + T   V  LL  +EY FRV A+N YG  EP +  
Sbjct: 15213 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15272

Query: 1420  ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
              +  V     P+ PK+ EV     D        P+ D  +  IN        Y +E R  
Sbjct: 15273 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15322

Query: 1472  SGKFGQVFRLVEKKT 1486
               K GQ +    KKT
Sbjct: 15323 -DKAGQRWIKCNKKT 15336



 Score =  100 bits (249), Expect = 1e-20
 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V AGE +++     G      TW K    ++++  +  E++EN S LTI  A +E  G Y
Sbjct: 15787 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15846

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + + N  G     +N+ V+DKP PP G     ++ + S+TLSW    YDGGS++ +Y +
Sbjct: 15847 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15906

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             E  D++  TW+ + AT   T+     L    EY+FR+ A N YG S
Sbjct: 15907 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15952



 Score =  100 bits (248), Expect = 2e-20
 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)

Query: 512  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
            V   F S +K+  ++EG      C + G P+P+I W  +G+ I    +Y     + G A 
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
            L I   LPED G YT  A N  G   CS  + V          Y   L PV+  +  +P 
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362

Query: 624  -------------------------------------------------IFLQGLSDLKV 634
                                                             +F+      K 
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            ++G      ++V G P PE  W H+G +I    +     ++ GTQ SL I    P D+G 
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            +T  A N AG      +LTV+      +P F+ K ++V    G  + +     G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541

Query: 753  HWLRD 757
             WL++
Sbjct: 1542 VWLKN 1546



 Score =  100 bits (248), Expect = 2e-20
 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+V   A++  S  +L     +V  +PL     FI P  ++ + E   AKFE  V   P+
Sbjct: 5446 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5496

Query: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
                W +  Q IT   RF L+  G + +  +   A  +E +  +  E  + SG       
Sbjct: 5497 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5555

Query: 115  --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
                    + VT +      F  +L    +                       KT    F
Sbjct: 5556 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5615

Query: 145  SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
               +++    I  E                P F  KL      E       C+I+    P
Sbjct: 5616 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5675

Query: 191  QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
             V W K    ++PS    +      ++L +    + D+G YTC    G+ K S   ++  
Sbjct: 5676 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5732

Query: 249  ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
                      S++ +++    F  ET+ +  D+            +     I +E K+ S
Sbjct: 5733 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5790

Query: 288  LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
            L       NC   Q GG    AAN +       K      L   KD   TA +T      
Sbjct: 5791 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5846

Query: 342  SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
             S         L+  +++P  +      + P  E +      R      +    G   + 
Sbjct: 5847 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5896

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
            +K       +  +      +F    + Q V+E  T    CEVS     +V WF  GT + 
Sbjct: 5897 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 5953

Query: 456  RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
            + +   E+  D     L +      D  TY+C A + +   SC+       L V+     
Sbjct: 5954 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 6003

Query: 516  FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
            F   L D  V E +    +C +      ++ W  +G  I+  +      +  V  L I  
Sbjct: 6004 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 6062

Query: 573  ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
             L +D   Y+C    A      S  +TV E+++                  +F + L+++
Sbjct: 6063 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 6100

Query: 633  KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            +V +   + +  +VS  P  EVIW     EI E+  +     G +  L IQ    ED G 
Sbjct: 6101 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6159

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            Y C   +S    RT   + V E        FISKP+++    G+     C+I+ + FP V
Sbjct: 6160 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6210

Query: 753  HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
             W RD K L +    ++V+ +     LV+K       G Y +++
Sbjct: 6211 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6253



 Score =  100 bits (248), Expect = 2e-20
 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)

Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
            MPP I    E  +V  G +V +  K+ G    T TW K        ++ +    H+    
Sbjct: 9744 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9802

Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
             ++   L I  +R+   G YT+   N LG+   ++ L V+ +P PP G      + +  +
Sbjct: 9803 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9862

Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
            TLSW+    DGGS + +Y IE  ++  KTW  +++  +  ++ +  LL  HEY FR+ A 
Sbjct: 9863 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9922

Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
            N YG  EP        +  +PE  ++   V  + D      V   ++T+N E+   D
Sbjct: 9923 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9971



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)

Query: 289  EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
            E  + +K    PQR  S P       +P     P E+ +++             ++KT+ 
Sbjct: 693  ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750

Query: 344  SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
              T +   V   PR       SP     K   P             G +  ++ +A   +
Sbjct: 751  LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796

Query: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
              E    S+  K     ++  VK ++T   R      P P+   F +     + E  +EV
Sbjct: 797  QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852

Query: 464  YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
             ++ G   + +     R+          A+   +      VE   +    P+  S LK+ 
Sbjct: 853  KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
             VIEG+   L+C + G P P +TW      I+ +   + T ++G+A L I++A  ED G 
Sbjct: 907  TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966

Query: 581  YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
            +TC A N  G VS S ++ V      EK+++  +E                         
Sbjct: 967  FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026

Query: 615  -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
               P +P AP F+      K+++G  V    QV GNP P V W  +G  +     +   +
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             ++  +  L I   F +D G YT    N  GE    A L  +  ++
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P+ +M P+   F +   V AGE+  L   V G    T  W++  K+I+ES   +++N++ 
Sbjct: 17251 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17307

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
              + L +  A +   G Y L   N  GS+   VN+ V+D+P PP G    + + S   +L+
Sbjct: 17308 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17367

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
             W     DGGS +  Y +E  +++   W  +A+   + S  V  LL  +EY FR+ A+N Y
Sbjct: 17368 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17427

Query: 1411  GTSEPSQES 1419
             G  EP + +
Sbjct: 17428 GVGEPLESA 17436



 Score = 97.8 bits (242), Expect = 9e-20
 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)

Query: 426   KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +E   VK+ C++    +  +V W+     +   E     YED G   L +      D GT
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25266

Query: 485   YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
             Y C   N  G+ S                 C  T++      + + ++E  P F+  L +
Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25326

Query: 523   CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
                  G++     ++   P P +TW  +GQ I+   +        + G+ +L I     +
Sbjct: 25327 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25386

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
             D   YT +A N  G+ SC A +TV           L P        P+F + L++ +  +
Sbjct: 25387 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25436

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
             G  V   ++VSG PPP + W  +G  +    +      G   ++L I++  PEDTG Y  
Sbjct: 25437 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25496

Query: 696   EAWNSAGEVRTQAVLTVQ 713
              A N+AG    QA L V+
Sbjct: 25497 TATNTAGSTSCQAHLQVE 25514



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G +V L     G    + +W+K    ++ESE ++   +EN   L+I  A++EH G Y
Sbjct: 21203 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21262

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T++++N +      + +  +  P  P G     +I++ S+ LSW     +GG  +  YSI
Sbjct: 21263 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21322

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  +++   WK + ++   T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21323 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21370



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)

Query: 161   PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
             P+   ++    V  GQ  RF   +  +P  +V W    V LQ S+++  +  +G+  LEI
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26061

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
                + DD G Y  +  N  G+AS  A L + G D    +  R  +     V  E+T    
Sbjct: 26062 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26121

Query: 279   --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
               +S   K   +EA++  +   S     +    + S  +    ++++S     ++  +  
Sbjct: 26122 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26178

Query: 337   VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
               +K  +++   AAR+  +PR+    +    GE  +          PT    L    V+S
Sbjct: 26179 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26230

Query: 397   KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
              +A  ++     + +   +  S   S E     V EN   K   E +  I K  V     
Sbjct: 26231 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26288

Query: 451   GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
              +P R +     V           +K+  R  S   S   + +  +   + T +V+ L V
Sbjct: 26289 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
                 P  +  LK  A    +   L C V  + +    +TW  +G+ ++    +       
Sbjct: 26343 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399

Query: 564   GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
             G  EL I +    D G Y C      G      Q    A+ ++HEK        KS +K+
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459

Query: 610   EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
                     ++P AP       + + GL D  V   S     V+ +G P P  IW  +G  
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519

Query: 663   IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             I +   +   +      L I +    D+G YTC   NSAG V +   LT++   D
Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26574



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG +V L   V G    T +W K    ++ +E +K+    N   L + +  ++  G Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN  GS+ A + L V+DKP PPA     + + S    LSW     DGGS + +Y +
Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13053

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             +  +++   W ++ AT   TS +V+ L+  HEY+FR+ A N YG  +P
Sbjct: 13054 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13101



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)

Query: 5     KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
             K +    I+KTS + +  R  +    E  AF      + I EG     +  + G  +  V
Sbjct: 26646 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26696

Query: 65    TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              W  NG  +T+   +    G+ G+  +L I      D G  TC +    G  +   +LT+
Sbjct: 26697 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754

Query: 124   EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
                          SK L D   APA  ++P                  + EGQ   F+C+
Sbjct: 26755 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26784

Query: 184   ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
             I+G P P++ W K N+P+  S+ VS+S    +  LEI   +  D G YT    N  G+ S
Sbjct: 26785 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26844

Query: 244   MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
              +A L +  L                 V +    V+ + S   SL+   +++S   S+ +
Sbjct: 26845 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26887

Query: 302   RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
             +  S    ++S      E K  S      ++ Q   ++ +SSS                +
Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26932

Query: 362   GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
             G+ + +  E                    S   + KA  R IP         PK E+ P 
Sbjct: 26933 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26964

Query: 422   SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
                + E + +   C  +G P PEV W   G  +  QE G   +        L ++  + +
Sbjct: 26965 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 27024

Query: 481   DSGTYSCTASNAQGQLSCSWTLQVERL 507
             D G Y+ +  N  G  S +  + +  +
Sbjct: 27025 DGGLYTLSLGNEFGSDSATVNIHIRSI 27051



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)

Query: 1228  PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P T      PP + + F +   +R GE+  L G+ +G      +W K    + E +   +
Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
             + +     L  + A++   G Y ++VEN  GSR+    + VVD+P PP G     ++   
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
              + +SW     DGGS + +Y IE  +     W  + +  + T+  V  LL   +Y FR+ 
Sbjct: 10556 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615

Query: 1406  AINVYGTSEPSQESELTT-----VGEKPEEP 1431
             A N+YG S+P     +       V + P++P
Sbjct: 10616 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10646



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            +G    + + +    K P      P I     D  V  GE + +          T +W K
Sbjct: 7994 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
              K+++ S+ + ++N    + L +  + +   G YT+ +ENKLGS  A +N+ V+  P P
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8110

Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
                  ASDI  SS  L+W    +DGG+ +  Y +E  ++  +T+  + +  +  S+ V+
Sbjct: 8111 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8169

Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
            DL+P+ EY FRV+A+N  G  E   E +   + + P++P D   +VEV +   +   + +
Sbjct: 8170 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8228

Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
            +    +   K+  +  I E++  G+
Sbjct: 8229 KPPLYDGGSKIMGY--IIEKIAKGE 8251



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)

Query: 506   RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
             ++A +E+ P    ++      EG      C +       ++TW    + ++ +     T 
Sbjct: 25189 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25247

Query: 562   EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
             E GVA L+++D    D GTY C   N  G+ S  A + V               KK  R+
Sbjct: 25248 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25307

Query: 609   SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
             ++ + L   P + T P++     +     G  V   V ++ +P P V W  +G +I+  +
Sbjct: 25308 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25362

Query: 668   D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
             +   + FE     + L I  V  +D   YT  A N  GE   +A LTV     P D T +
Sbjct: 25363 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25422

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
             P F     +     GQSV     ++G P PT+ W +DG+ L        + +  D + L 
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482

Query: 781   LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             ++   P   G Y +   N  G  SCQ  L ++
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514



 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)

Query: 1249  VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             ++AG+++ L    + G      +W K  K I+ S+  ++ ++   S LTI  A ++  G 
Sbjct: 14018 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14077

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+   N  G++   V +TV+D P PP G    S++ +   TL+W     DGGS ++SY 
Sbjct: 14078 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14136

Query: 1368  IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E  +++   W    +++ +CR  +     L+  +EY FRV A+N YG  EP Q   +  
Sbjct: 14137 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14193

Query: 1424  VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             V    P  P ++ EVS+       V   T T++ ++ V D
Sbjct: 14194 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14226



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S+ +F  + G      TW K    I       +EN+E+ + L I    +   G +
Sbjct: 14416 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14473

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + +EN  G +   VN+ V+D P P       +DI   S+TL W     DGGS + +Y +
Sbjct: 14474 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14532

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++    T C   ++ V  L    EY FRV A N YG  EP++ +E     E 
Sbjct: 14533 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14592

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
             P  P D + + D  +    + +     +   K++ +    +R GS ++  +
Sbjct: 14593 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14642



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+  M    ++F +   V+AGE +++   + G      +W K   +I+E    ++ +++
Sbjct: 19414 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19470

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
             N + LT+    +   G Y L ++N  G+R   VN  V+DKP PPAG    + + +   +L
Sbjct: 19471 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19530

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             SW     DGG+ +  Y +E  ++++  W       + TS  V  LL  +EY FRV  +N 
Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19590

Query: 1410  YGTSEP 1415
             YG  EP
Sbjct: 19591 YGVGEP 19596



 Score = 94.4 bits (233), Expect = 9e-19
 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ L   V+G  P   TW K  + I  +    ++ +E+ S L +    +   G Y
Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23143

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN+ G + A V + V D P P        ++   S+T++W   + DGG+ V +Y +
Sbjct: 23144 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23202

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++A + +K + T C  T + +  L+    Y FRV   N+YG  EP + S+   V E 
Sbjct: 23203 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23262

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             P  P  ++EV D       V   TVT+  E+ + D
Sbjct: 23263 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23289



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+A E +++     G    T  W K  + ++E+  + V +S+  + L+I  A +E  G Y
Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19093

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L V N  GS    + + V+D+P PP G     ++   S+T+SW    YDGG  + +Y +
Sbjct: 19094 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19152

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++ + TW  ++     TS  +  L    EY+FRV A N YG S  S+ S    V E 
Sbjct: 19153 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19210

Query: 1428  PEEP 1431
             P  P
Sbjct: 19211 PFSP 19214



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
            +AG  + +   + G      +W    K +K +++  H      ++E +EN S + I   +
Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            + H G Y++  +NK G + A   + V+D P PP      SDI   S  LSW     DGG 
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9569

Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             ++ Y IE      K W ++   C ST+F V DLL + +Y FRVRA N +G   P +  +
Sbjct: 9570 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9629

Query: 1421 LTTVGEK--PEEPKDEVEV 1437
             TT  +   P +P  ++++
Sbjct: 9630 RTTARDPIYPPDPPIKLKI 9648



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            + P F     +L +K    A FE R+   G P   V W  +G+P+ +  R  +     G 
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
             SL     +  D G  TC ATN  G    +  L V  E S  ++   P   K L      
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773

Query: 147  PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
              +    ++ G       +  P        V V EG+  RF C++TG PQP+V W     
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             ++ S R  V   +G+  L+I      D G       N  G      +L IQ  +   RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891

Query: 260  FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
             +R       +        +  E  K+D      ++K     +R          +     
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951

Query: 319  ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
             SK +   +       T V  K+          ++             + EE+K  A   
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              T PT +P              +I +    ++  PK   + QSQ V +     FR  V 
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
            G P PE  W+  G  + R +     + +     L +      DS +    A N  G+ S 
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
               L V+   ++    +F+  L+D    E             P  ++ W  +G  +    
Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172

Query: 558  --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
              R   +  V  L I      D   Y+C              V V ++     ++ ++  
Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218

Query: 616  APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
            A  +     F++ L D++V +     +   VS    PE I   W HN  E++ +  +   
Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269

Query: 673  QRGTQHSLCIQEVFPEDTGTYT 694
             R  + +L +++V  ED G Y+
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
             P A++ P+   + +   V AGE+  L   + G       W K  K+++E+   M+++++ 
Sbjct: 18333 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18389

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L +    +   G Y L + N  G++   + + V+D+P PP G    + + +    L
Sbjct: 18390 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18449

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y IE  +++  +W +++T  ++ ++ V  LLP +EY FRV A+N 
Sbjct: 18450 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18509

Query: 1410  YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
             YG  EP +   +T     KP  P    EVS
Sbjct: 18510 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18539



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
             T +  TV+      T   + MP + I  P      AG  VEL   + G  P   +W    
Sbjct: 23351 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23404

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
              +++ESE + VE     +KLTI        G YTL ++N  G+    + + ++DKP PP 
Sbjct: 23405 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23464

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
             G     +I ++S+T+SW     DGG+ +  Y +E  D+    W  ++ +   ++F    L
Sbjct: 23465 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23524

Query: 1395  LPDHEYKFRVRAINVYG 1411
                +EY FRV A N +G
Sbjct: 23525 TEGNEYVFRVAATNRFG 23541



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            +P+T  P  +   +N+ + EG +   E  + GYP P VTW+R    I S   F +     
Sbjct: 892  IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
            G   L+I     ED G++TC A N +G    +  L V+ S   +     V++   T   R
Sbjct: 950  GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009

Query: 144  F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
            F  S   V T  S+  E         P F TK     + EG    F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069

Query: 195  LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             K  VPL    R  VS +++ G   L I     DD G YT +V N  G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AGE V++     G  P T TW K  K +       +EN+++ S LTI    +   G Y 
Sbjct: 20912 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20971

Query: 1310  LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             L +EN +G  + + V++ V+D P           +   ++TL W     DGGS + +Y I
Sbjct: 20972 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  D+  +TW  ++  C STSF + DL     + FRV A N  G  EP + +E     E 
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21090

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
             P  P  ++ + D  +    + +     +    ++++  + ER G G+
Sbjct: 21091 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21134



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+ G+ +++   ++G    T TW K    ++++  + V +S + + L+I    ++  G Y
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + V N +G + A + +  +DKPDPP G     D+ + S+TLSW    Y GG  + +Y +
Sbjct: 16929 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16988

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             +  D+    W  + AT   T+  V  L    EY+FR+ A N YG S
Sbjct: 16989 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)

Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
            KV+AGE V +   VTG       W K    I++          +V  SE  ++L+I  A 
Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            +E  G YT+   N+LGS    V++ V D+P PP      +DI++ S  L+W     +GGS
Sbjct: 9097 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9155

Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
             +  Y I+  D++ K   W+E+  T     + +  L+P+ +Y+FRVRA+N YG S+  + 
Sbjct: 9156 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9215

Query: 1419 SEL 1421
             ++
Sbjct: 9216 DKV 9218



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)

Query: 1226  PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
             P P        PP++I       +Q ++ G+++ L   + G      TW K  +      
Sbjct: 10832 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10891

Query: 1283  HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
              + V  +  GSKL I  A  E  G Y+L VEN  GS+   V + V+DKP PP      S+
Sbjct: 10892 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10948

Query: 1343  IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
             IR  S  L+W     DGGS + +Y +E  D A+  W  L AT +  S   + L   ++Y 
Sbjct: 10949 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11008

Query: 1402  FRVRAINVYG 1411
             FRV A N YG
Sbjct: 11009 FRVAAENQYG 11018



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)

Query: 1232  PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
             PKA    +PP+I    + +KV   RA  ++ LF  + G       W   R   +  +   
Sbjct: 15477 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15534

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             +E++ + + L +    +   G Y L VEN  GS+ A VN+ V+D P PP       ++  
Sbjct: 15535 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15593

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S+TL+W     DGGS +++Y +E  +S  K +  +AT C  TS+ V  L     Y FRV
Sbjct: 15594 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15653

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A N YG   P++ +E     E+P  P
Sbjct: 15654 LAENEYGIGLPAETAESVKASERPLPP 15680



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)

Query: 1249  VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             V AG  + +   V+G  P T TW M  R   QE+    +E +   S + I   ++ H G 
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10220

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
             Y+LL +N+ G R+  + + V+D P  P GTP  A ++ + S  L+W+    DGGS + +Y
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10279

Query: 1367  SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
              IE  +S  + W  +  T    +  VQ L+    Y FR+ A N  G     + SE   + 
Sbjct: 10280 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10339

Query: 1426  EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
             E    PE P+D +EV        EV   TVT+       D       Y +E RL G+ KF
Sbjct: 10340 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10391

Query: 1476  GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
                     K T      + +     KE +     +S +N +   K   C
Sbjct: 10392 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10433



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ LF  + G       W K   +I+++  + V +S   + L +    +   G Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16639

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL +EN  G++ A V + V+D P PP      ++I   S++++W     DGGS +++Y +
Sbjct: 16640 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16698

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++  + T C   S+ +  L     Y FRV A N YG   P+Q ++   V E 
Sbjct: 16699 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16758

Query: 1428  PEEP 1431
             P+ P
Sbjct: 16759 PQPP 16762



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)

Query: 1228  PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
             P   P      +++++P+   D++ + G  V   G +  T PI       C W K  + I
Sbjct: 23746 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23805

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
               S+   +  SE  ++L I  A +   G Y L++ENK G +   + + V+  P+ P G  
Sbjct: 23806 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23863

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
                DI+  S+ +SW   + DGG+ +  Y +E  +     W  + +  R TS  V+ L  +
Sbjct: 23864 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23923

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
              EY FRV A N +G S+P +  E  T       PE P +  EV D  +    + +     
Sbjct: 23924 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23983

Query: 1455  NTEQKVSDFY 1464
             +   +V+ +Y
Sbjct: 23984 DGGSRVTGYY 23993



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)

Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
           AP F Q L  + V++GS  T    +SG P PEV W  +G  I  S            +  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
           L I  V   ++G Y+ +A N +G+  + A L V+   +   P F+ + +S+T   G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122

Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
           +   + G P P V + RDG  + + +  F++ Q  D+++L++ +  P  +G Y +   N 
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 800 VGECSCQVSLMLQ 812
           VG  +    L++Q
Sbjct: 182 VGRATSTAELLVQ 194



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)

Query: 408  QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
            Q++   P     P+   V E +T +FRC V+G P+P+V W+L G  +R+ +     Y+  
Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846

Query: 468  GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
            G HYL ++  ++ D+G    TA N +G +     L++++         F SVL+      
Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900

Query: 528  GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
             +  V     LQ  V+    P        +  L   + I + +   E+   EL  +    
Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958

Query: 576  EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
             + G Y  +              E  L +       W      E+K +   E  + +   
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018

Query: 619  KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            KP          AP   + +    V  GS     V+V G P PE  W  NG +I+ S+  
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078

Query: 670  H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
            + +        L I++V  ED+ +   +A N AGE  + A L VQ     T   F  + +
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135

Query: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
             V A    ++        +PF  V W +DG
Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)

Query: 1232  PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
             PK  + P  I      +    VRAG  + LF  V G      TW K      +++ +   
Sbjct: 12225 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12281

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             V+  +  + L I  + ++  G Y+L + N  G +   VN+ V+D P P +     SD+  
Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12340

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S  +SW     DGGS V  Y +E  ++  KTW  +    + TSF+V +L+P +EY FRV
Sbjct: 12341 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12400

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A+N YG   P+   +     +   EP
Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEP 12427



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)

Query: 1228  PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             P   P    P  I+  PE +          +RAG ++ L+  V G  P   TW K    +
Sbjct: 13303 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13362

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             ++   + +++++  + L      +   G Y L +EN  G ++  + + V+D P PP    
Sbjct: 13363 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13421

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
                +I   S  ++W     DGGS + +Y ++  D+  K+W  + T C  TSF V +L   
Sbjct: 13422 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13481

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
               Y FRV A N YG  +P +  +     + P
Sbjct: 13482 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13512



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)

Query: 1237  PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    + +KV   RA  ++ LF  + G       W K    +  ++  ++E + + +
Sbjct: 18732 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18789

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L I    +   G Y L +EN  GS+ A VN+ V+D P  P       +++  S+TLSW 
Sbjct: 18790 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18848

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DGG+ + +Y +E  ++  K +  +   C  T+F +++L     Y FRV A N YG 
Sbjct: 18849 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908

Query: 1413  SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
               P++ +E   V E P  P     V        +V   T TI  E+  SD
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18950



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S  +     G      TW   R++ + ++ +++E   N ++L+I    +   G Y
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17721

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L +EN  GS+ A V + V+D P PP       ++R  S  L W     DGG+ V++Y I
Sbjct: 17722 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17780

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             +  +S  K +  +++ C  TSF V++L     Y FRV A N +G   P +  +     E 
Sbjct: 17781 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17840

Query: 1428  PEEP 1431
             P  P
Sbjct: 17841 PSPP 17844



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             ++AGE +++   V G      +W+K  + ++++  + VE +   + L I    ++  G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+   N  G+    +++ V++KP PP G     ++ +  + +SW   +Y GG  + +Y +
Sbjct: 18011 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18070

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  D+   TW  + AT   T+  +  L    EY+FR+ A N YG S P
Sbjct: 18071 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18118



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
           P F    QS  V E  T  F   +SG P PEV+WF +G  +       +++    G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
            +      +SG YS  A+N  GQ     T   E L   E A P+F   L+   V +G   
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121

Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
            LQ  V G P P + +  +G  IQ +   + + E  +  L I +A PED GTY+  A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
           +G+ + +A + V   E+  ++K++ ++  A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+L P +    EG TA+F+ +V G P P+  W  +GQ I +     +     GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            I      D G++T  A N +G   ++V LTVE                       AVE  
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
                 +  P F  KL  V +KEG       + TG P P + WLK +  + P    ++ + 
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               G   L+I      D   YT   +N +G+ +   +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)

Query: 1261  VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
             + G    + +W K    +     + VE+S   + L +   ++   G YT+ ++N  G+++
Sbjct: 13634 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
               +++ VV KP  P G     ++ + ++TL W     DGGS + +Y +E  DS N  W  
Sbjct: 13694 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13753

Query: 1381  LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
              A+  + T+F V  L    EY FRV A N YG  E
Sbjct: 13754 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13788



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)

Query: 1237  PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    FP     VRAG ++++   ++G      T  +    ++ +     E +    
Sbjct: 20101 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20160

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              + +  +     G Y +   N  G+ +A +N+ V+D+P PP G    SDI   S+TL W 
Sbjct: 20161 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20220

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                YDGGS V +Y +   +++   W E+ AT   T   V  L    EY+FR++A N +G 
Sbjct: 20221 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20280

Query: 1413  SE 1414
             S+
Sbjct: 20281 SD 20282



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)

Query: 1238  PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             P I++F  +      +++GES+ +   V G      TW K   +I++  +M++ +    +
Sbjct: 21583 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21642

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L +  A ++H G YT+  +N  GS +A++ + V D P    G    ++I    +TL W 
Sbjct: 21643 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21702

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DG + +  Y IE  +++   W  +   C + S+    L+  +EY+FRV A+N +G 
Sbjct: 21703 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21762

Query: 1413  SEP 1415
               P
Sbjct: 21763 GRP 21765



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)

Query: 882  HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
            H EE+  QQ   +  +++    ++S   ++E   +  PA +      + + VKP+ +   
Sbjct: 676  HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726

Query: 939  SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
            SE   K    + +   S + K     T     V   P+ A+P F      K  +P     
Sbjct: 727  SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783

Query: 998  SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
              A    +      K LS    +   + +  +  A T+KP      AE   L     A  
Sbjct: 784  YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840

Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
             +  KS +  E+KK+V   +       GTT  E+R E                       
Sbjct: 841  PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            T P     L++V V EG+ + L+C +S  P  T+ W      ++++    ++ +  +  +
Sbjct: 895  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
             I +A  ED G + C A N+AG    SC   V V +    E T   E  +   K  +   
Sbjct: 955  MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                +D ++ ++ A    P A   P  I  P  QK+  G SV    +V G       W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071

Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
                +      KV  N + G  KL I     +  G YT++V NK G   A  +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)

Query: 405  MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
            ++G++ +   K + +P         Q+V E   V+   +VS +   E  W  +G  V+  
Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352

Query: 458  EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
            +  + +  D  SH L +      D+G YS T       L  S + +V   +V  + P   
Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
              LKD  VIEG   VL+C V    V  + W LN + I+     ++  +     L I    
Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462

Query: 575  PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
              D G Y  +    +G+V  +  ++V + K                     ++GL DL  
Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
             +   V   V++S +   +V+W     EI+ S  +  E  G  + L +  +  +D G YT
Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
                  AGE  T   LTV           ISKP    T +  Q  +  C +A +P     
Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605

Query: 754  WLRDGKAL 761
            WLRDGK L
Sbjct: 2606 WLRDGKHL 2613



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)

Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
            D E R++ +   AP  K   QD+ V  GK L +     + P A   W    + L T    
Sbjct: 6615 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6674

Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
              +++ S   +  +K    D+G YK V +N  G+AE    + V D P             
Sbjct: 6675 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6719

Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
                   PV   E   T   +               +    ++ +  G S ++ G V   
Sbjct: 6720 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6756

Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
            + I   TW+    + +  E       + G +     + +   G    +  +N + +R   
Sbjct: 6757 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6816

Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
                  D P PP      +D+    ++L+W    YDGG+ + +Y IE+ D  +  W    
Sbjct: 6817 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6869

Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            T R+   S  V D++   EY FRVRA N  G  +PS  +    V +  E P   V ++  
Sbjct: 6870 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6929

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
            D+ +  V  +      +        I ER   GK   +    +LV + T KV       K
Sbjct: 6930 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6989

Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
            +    SA+ K  +     I+  L
Sbjct: 6990 YLYRVSAENKAGVSDPSEILGPL 7012



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG S  +     G       W K    ++   +  V+ +++ + LTI  A +   G Y
Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19883

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL ++N L +    + + V+D P PP       D+   S  LSW     DGG+ V++Y I
Sbjct: 19884 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19942

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  +++ K W  +   C   S+ V +L     Y FRV   N +G   P++  E   + EK
Sbjct: 19943 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20002

Query: 1428  PEEPK 1432
             P  P+
Sbjct: 20003 PSPPE 20007



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             E + S  SE + P +     AP F + L +L V   S  T+  +V+G+P P V W   G 
Sbjct: 24535 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24594

Query: 662   EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
             EI  +   +  ++ +G  H L I  V  +D   Y   A N  G V   A L V+ P    
Sbjct: 24595 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24654

Query: 720   QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
              P  +    +V A  G+ V I    +G P P + W + G+ L  + GH++V+      +L
Sbjct: 24655 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24713

Query: 780   VLKK-VQPWHAGQYEILLKNRVG 801
             V    V+   AG Y +  KNR G
Sbjct: 24714 VFPNGVERKDAGFYVVCAKNRFG 24736



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)

Query: 23    RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
             R D+M L E P  F LP  N     G   +F   +  +PEP VTW+++GQ I  G    +
Sbjct: 25307 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25366

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
             +  +   +G + L I++V  +D  +YT  A N  G      +LTV       L  P    
Sbjct: 25367 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25419

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             TL                    P F   L     +EGQ   F  +++G P P + W K  
Sbjct: 25420 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460

Query: 199   VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
              PL     +  + E      L I     +D G Y     N +G  S  A L ++ L    
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520

Query: 258   RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
             + F +  +     V+K++   +     L   E+
Sbjct: 25521 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25552



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
             V+AG+++ L   V G       W K +    +  S  +K++   + SK ++  A++   G
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11900

Query: 1307  CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
              Y +   N  GS  A   + V+DKP P        D+ S   T+ W     DGG  +Q+Y
Sbjct: 11901 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11959

Query: 1367  SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
              +E  ++    W    AT  +    V  L+  +EY FRVRA N  GT  P++   +   T
Sbjct: 11960 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12019

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
               +KP  P D  EV+   ++E  V +     +  + ++ ++
Sbjct: 12020 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12059



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)

Query: 622   APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
             AP   + + D+    G    ++ Q+ G P P++ W   G E+ +S  +     G  H+L 
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219

Query: 682   IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
             +     ED G YTC A N  GEV T + L +Q       P +  K +   A +G ++ + 
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24277

Query: 742   CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
                 G P P + W   G+ L +++ +  +   E    LV+K VQ   HAG+Y++ L N  
Sbjct: 24278 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336

Query: 801   GECSCQVSLMLQN 813
             G     + + +Q+
Sbjct: 24337 GTVDAILDVEIQD 24349



 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)

Query: 416  FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            F  + Q    KE  T+  F CE S  P  +V W+ +G  V   +    ++ D   H+L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
            L   T D+  YSC     +   + +      +L V      F   L+D  V E     L+
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241

Query: 535  CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
            C V    +    W  N   ++       T   G   L ++D   ED G Y+ + +     
Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                       KK++ K +        KP     LQGLSD KV +G  V + V+VS    
Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338

Query: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
             E +W+ +G E+Q S+  H       H L I+++  ED G Y+        +++G V   
Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
            +V              I+  + V    G   ++ C ++     +V W  + + + K    
Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
             + +       LV+ +      G Y++++  RV E +C +S+
Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            + E ++  F  E+S    P   W L+G  + R   + E+  + G  +L L K +   +G 
Sbjct: 5036 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 5093

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
                A NA         +    L V E+   F+  LKD  V E +    +C +  T    
Sbjct: 5094 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5142

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
            + W      I+ +         + HI    D+  +D G YT   E    + S   +VT  
Sbjct: 5143 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5200

Query: 602  EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
              K                    F+  L D  V +G   T   ++S +    V+W  N  
Sbjct: 5201 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5239

Query: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
            ++  S        G  H L ++EV  +D      +      E+ + A L V E      P
Sbjct: 5240 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5291

Query: 722  WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
            +F  K    TA     + + C ++ D    V W +DG+ +      + +  +     L +
Sbjct: 5292 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5348

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
            KK      G+Y          C C       N +  A L +  +P    ++  G      
Sbjct: 5349 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5399

Query: 838  ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
             +    D +G     W  +GQ      D E +    K  +         T + + +A   
Sbjct: 5400 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5455

Query: 890  QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
            +    L  ++L    +    LS  D+K    ++  F   + R+  PKT     R +   Q
Sbjct: 5456 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5505

Query: 950  QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
            ++  D R  L K GT  + V +       A   F +      +    +G    E +  K 
Sbjct: 5506 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5559

Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
            +   K ++  +    +  V  +     +K   N +   T + + + + +    S + ++L
Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5618

Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
              D  + +  +    G +   K +  +G  P F  KLQD    E  +++LQC++S    A
Sbjct: 5619 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5674

Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
             + W  +GK +K +K  ++  +G    + ++KAL  D G Y C    D G  + S ++ +
Sbjct: 5675 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5730

Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
            +D          E+K  RP  S+  V+ TE+
Sbjct: 5731 EDR---------EIKLVRPLHSV-EVMETET 5751



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PPKA +  ++    +   +RAG  + L   V G       W K  K++   E + ++ + 
Sbjct: 22671 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               +   I    +   G YTL V+N  G++   V + V+D P  P G    S +     TL
Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22787

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y +E  +++   W  +   C + S+ V  L+ ++EY FRVRA+N 
Sbjct: 22788 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22847

Query: 1410  YG-----TSEPSQESELTTVGEKPEEPKD 1433
             YG      SEP       T+   P  P++
Sbjct: 22848 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22876



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AG+++++   V G    T TW K  + +++++ +  E +   + L I    +   G Y 
Sbjct: 14706 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14765

Query: 1310  LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             L   N +G     + + V D P PP G     ++ S  +T SW     DGG  + +Y +E
Sbjct: 14766 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14825

Query: 1370  IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
             +  + + TW ELA T   T++    L    EY+FRV+A N YG
Sbjct: 14826 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14868



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)

Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
            EED  +     ++E +  V+  F   I++  ++EG    F CK+ GYP P++ W+KD + 
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284

Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I+    +Q+D+ +DG  SL I  V  +D+  YT  A N  G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)

Query: 21   PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
            P +++  P  EAP      ++  + +G+ A F  RV G P+P+  W++NG  I    R  
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079

Query: 81   LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
                      LVI  V  ED      +A N +G       L V+   AKQL         
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127

Query: 141  GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
                                  F  +L  VV KE   M  F C+ T  P  +V W K  +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             +    +  +     +  L I  ++  D   Y+C++V        +A+L ++G   A   
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222

Query: 260  FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
            FV+E +          E+  ++S E+       + +E  +  K   + +RG       + 
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282

Query: 313  QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
              +   E       K  +CK   +  P   +LQ  S     +   VQ E +       GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341

Query: 364  LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
                G+E  +P+         +   L  +D+  + A      IP  G   S      S  
Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400

Query: 421  QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                +K+   ++       C+VS      V W+L    + + +  ++         L + 
Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
            +    D G Y        G++  +  L VE++ ++         L+D    E Q+ V + 
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508

Query: 536  SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
             +  + +  + W    + I+ +   +      + +L + + + +D G YT  A    G+ 
Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563

Query: 593  SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
              S  +TV               A SKP        L+D  V +  +     +V+ NP  
Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602

Query: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +  WL +G  +  + +   E  G +  L I     +D G YT +   S    +T A L V
Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658

Query: 713  QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            +          I K  +++T +  Q  + +  +       V W+++G  L
Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
             P+F     ++     + V+F   ++  P+P V W+  G  ++  +   +     D G + 
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
             L +    T D   Y+  A N  G+ SC   L V          + P F  +L +    EG
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25437

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
             Q    +  V G P P + W  +GQP+    +      G+    LHI+D LPED G Y   
Sbjct: 25438 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25497

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEY 611
             A N  G  SC A + V E+   +K E+
Sbjct: 25498 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25523



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)

Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
            +P+  TPP  A+ P  I  P+       +V+ G+ + L   ++G+   T TW+K      
Sbjct: 8292 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8349

Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
                             ++QE E         + ++NS+ G S+L +  + +   G Y +
Sbjct: 8350 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8409

Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
             VEN  G  +A   ++V+D P PP       DIR +S+   W     DGGS + +Y++E 
Sbjct: 8410 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8468

Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             D    +  W  + +T R   ++V  L+   EY FRVRA N +G   P     L  V + 
Sbjct: 8469 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8526

Query: 1428 PEEPKD 1433
            P  P D
Sbjct: 8527 PFGPPD 8532



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)

Query: 36   ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
            I P +++ + EG  A  E +V       V W+ N + I    R  +   ++GT   LVI+
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459

Query: 95   AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
              H  D G Y        G  +    L+VE                              
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487

Query: 155  IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
                   K    L  +   E Q   F  +++      V W   +  ++PS++  +     
Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539

Query: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
            +  L +  + +DD G YT      +G+   S +L++ G  + ++    +T A + +    
Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594

Query: 273  KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
             EV N  SK   L   +    + N  S   G        A           K+ + K S 
Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654

Query: 330  RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
            +   +   ++KT  ++T+   +          P   G+     GV+  S E+        
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              +   +   +  + V      R +    +      K   KP+     EN TV F   VS
Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
                P V WF +   ++  +    +  +   H L L      D+G Y+       GQL C
Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
               L VE L +       +  +K+  V E +    +C V    VP + WL NG  I+ + 
Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879

Query: 559  S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
                  +  + +L I +   ED   YT +  N   QVS +  VT                
Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921

Query: 616  APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
                   PI +   L D+   +   +T  V V+        WL NG EI+ ++      +
Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973

Query: 675  GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
               HSL I+ V   D   YT      AG+  + A L V+  H      F    + +    
Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             +  +  C ++ +P  TV W++D + L + T   ++ + + V  L++   +   AG+Y +
Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083

Query: 795  LLKNRV 800
            +    V
Sbjct: 3084 VAGGNV 3089



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)

Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
            P T   A + P   +  F +  +V     + +    TG    T TW    K ++  + +K
Sbjct: 7011 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7070

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
            ++     ++L I  + +   G YTL +EN++ +   ++++ V+ +P  P       DI  
Sbjct: 7071 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7129

Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ L+W     DGGS +  Y +E  + + KTW K +       F V DL+   EY F+V
Sbjct: 7130 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7189

Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
             A N  G  EP+   E   ++T    P+ P++
Sbjct: 7190 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7221



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PA  ++L  V  ++   +L   +   D  + I   L     K + F + +      + ++
Sbjct: 22174 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22233

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             E+ + +    ++  AKNDAG +E                         P+ +   V+   
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22265

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                 +K+     T     +  Q+I        +AG    +   ++G      TW     +
Sbjct: 22266 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22315

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
             ++E++ + +  +++ + LT+  + +   G Y L +EN  G +   V + V+ +P P  G 
Sbjct: 22316 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22375

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
                S + + S  LSW      GG+ + +Y +E  +S    W+ + ++ + T   V  L  
Sbjct: 22376 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
               EY FRV + N +G S+P + + +  + E P  P
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22468



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)

Query: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
            S+DVV    +      G  + A P F +KP  Q++ E  +V F C+V G PKP V W   
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072

Query: 451  GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
            G P+       +   +  G   L +      D+G Y+    N  G+ S S +L +E    
Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131

Query: 510  MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
              +  S   +L    V     FV +  V G   P   +    +  +  ++     +A+  
Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
            + ++  + +     +   E  + ++      T  E+  +   + +  + ++ S+     F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247

Query: 626  LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
               + + ++++G  VT   ++SG P P++ W  +G  I+  E +   F Q G + SL I 
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306

Query: 684  EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
             V PED G YT  A N  G       L V+       P +I             PRSV+ 
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366

Query: 733  S 733
            S
Sbjct: 1367 S 1367



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P  K       V  G+ L ++  +S  P  TI WT +G  LK T  I ++    L ++SI
Sbjct: 16858 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16917

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y     N  GQ   S ++   D P  +  K P                  
Sbjct: 16918 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16960

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              D + +       PP      QI  +   ++                   T  W      
Sbjct: 16961 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17004

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
             +  +  +KV   + G++             + +  EN+ G   A  +  +V      +P 
Sbjct: 17005 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17052

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
             PP GTP A+ I   S+ + W+    +GGS V  Y +E       +W   NKT        
Sbjct: 17053 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17106

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              T F  Q+L    EY+FRV A N+ G  + S+ SE     +  + P
Sbjct: 17107 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17152



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F + L+D  V E    +  CQ+S +  A + W  NG+ +K  K     ++GS+  + I+ 
Sbjct: 6453 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6511

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
               +D   Y C  ++   +A    + + V+         +AP ++     E+   +    
Sbjct: 6512 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6571

Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
              ++++  V G +                           + K    +   + A  P+I 
Sbjct: 6572 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6631

Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
               +D  V  G+ + +             W K  + +       ++ +   +   IL A+
Sbjct: 6632 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6688

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            +   G Y ++++NK G  +  +NL V+D P P       ++     ++L+W     DGGS
Sbjct: 6689 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6747

Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
             +  Y +E  D   KTW  LAT R+ S  F V  L     EY FRV A N  GT EP + 
Sbjct: 6748 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6806

Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
                    K + P   + V+  D
Sbjct: 6807 DNPVEARSKYDVPGPPLNVTITD 6829



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)

Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
            S TG+       E L   E  V++        E P   P     ++++ V+EG +   +C
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             I GYP P V W+++D  I  S  FQI + + G   L+I +   +D  ++TC AVN  G 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 1840 ATCTAELIVETMEEGEGE 1857
             + +  L V+  EE E E
Sbjct: 978  VSTSCYLAVQVSEEFEKE 995



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)

Query: 619  KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
            K   P+    L D    +G  V +T  ++     EV W      +   E F   Q    +
Sbjct: 4364 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4421

Query: 679  SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
            +L I +V  ED  G Y CEA N +G+  T A LTV +      P    K   +  +LG  
Sbjct: 4422 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4478

Query: 738  VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
               +C I   P     W + G+ +  ++    +  ++ + +L + + Q    G+Y     
Sbjct: 4479 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4537

Query: 798  NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
            N  G  SC  +L +         R L   R+P   E++                S+    
Sbjct: 4538 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4584

Query: 854  PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913
            P   +  +E +  E V    K+         + + + EV  +  R+   +K+   T   +
Sbjct: 4585 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4637

Query: 914  DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970
                IP    + +   + +V   KP  V  E   + +P  V    V+ KK  +K P  E 
Sbjct: 4638 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4694

Query: 971  VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027
              P  P       + G  KK P+   +   +       E      P +    + PLK V 
Sbjct: 4695 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4747

Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073
              K     +   +G++   E L     A     K   N++ + K     D K+       
Sbjct: 4748 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4807

Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124
                   +  C  + G+   T   K    +      K   ++V V +G+ L L C+++ +
Sbjct: 4808 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4867

Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183
                ++W  +GK  ++    I+    G + +++I  A   D G Y    +N A   ECS 
Sbjct: 4868 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4924

Query: 1184 QVTV 1187
             V V
Sbjct: 4925 CVKV 4928



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)

Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
            N++P ++LK   +E +  D +  +  +  +A G ++  + SE+         P    +  
Sbjct: 7963 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8022

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            D+ V EG+KL +     + P  T+ W  +GK +K +  + +  +     + + K++  D 
Sbjct: 8023 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8082

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            G+Y    +N  G A  S  V V   P        ++K+              SD T    
Sbjct: 8083 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8124

Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                 PP+                             G  PI   ++  R++     ++ 
Sbjct: 8125 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8156

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
            V + EN    T+          + +   NK+G  +     N  +   P  P   P   ++
Sbjct: 8157 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8216

Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
             +    ++T++W    YDGGS +  Y IE      + WK    C        ++  + L 
Sbjct: 8217 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8273

Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
               EY+FRVRA N  G SEPS+ +  T   +  + PK      +EV   DE
Sbjct: 8274 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8324



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            VKE Q V F CEV+     +  WF     +      I + +D   + L +  A   D   
Sbjct: 6279 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6336

Query: 485  YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
            Y+ + +N +G+ +  +  L VE   +  V P     LKD   +E +     C V    V 
Sbjct: 6337 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6391

Query: 544  RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
             + W  NG+ + +            H   I+D    D G Y                VT 
Sbjct: 6392 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6435

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
             + KS   +E L+  AP++     F++ L D  V +      + Q+S      V W  NG
Sbjct: 6436 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6487

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
             EI+E + + FE+ G+ H L I++   +D   Y C       + +++A L V+E P +  
Sbjct: 6488 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6543

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
            +P     P+ +  + G  V+    +  D    V WLR+   + +   H +++    +  L
Sbjct: 6544 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6596

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             +  ++P   G+Y  + K++      +++
Sbjct: 6597 QICDIKPRDQGEYRFIAKDKEARAKLELA 6625



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V+V  G  L +   +S  P   +  + +G  LK T            ++++++++  D G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
              Y+  A N +G  +    + V D P                   P V+   TE   T+K 
Sbjct: 20174 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20219

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P PK    + +   I+       ++   S  ++ +V+ T  +  T MK  K     E+ 
Sbjct: 20220 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20269

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
                 +EN                    + + + S    V L     P PP+ TP  +++ 
Sbjct: 20270 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20310

Query: 1345  SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
               S+T+ W+    +GGSAV  Y +E+ D  +  W++      R+T F V  +     Y+F
Sbjct: 20311 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20370

Query: 1403  RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             RV A N  G  +PS  SE     +  E P++ V ++D  +    + ++    +   K++ 
Sbjct: 20371 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20429

Query: 1463  FYDIEER 1469
              Y +E R
Sbjct: 20430 -YIVERR 20435



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 33/91 (36%), Positives = 56/91 (61%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P+F K ++ +   +G  A F+  + G P P V WFK+++ +  S ++ I ++ +G+ + I
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            ++D   +D   Y CKA N LGE+TC AEL+V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
             R+++ ++    +++   G+ L +   ++     + +  EN+ G      S +     T +
Sbjct: 23895 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23954

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
             + P+PP+  P   D+  SS++LSW     DGGS V  Y IE  +++   W         +
Sbjct: 23955 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24014

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
             T + V  L+PD EY+FR+ A N  G SE S  SE        +KP +P  E+E+
Sbjct: 24015 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24067



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)

Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
            P+ PP   +    +      ++ AG+++ +   VTG    T  W K   ++ + + + ++
Sbjct: 8726 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8781

Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
            N    S+L I  A ++  G Y +   N  GS+ A   + V D P P          R   
Sbjct: 8782 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8841

Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
            L L+W     DGGS +  + IE  D+   TW++      +  ++  LL   EYKFRV A 
Sbjct: 8842 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8900

Query: 1408 NVYGTSEPSQESELTTV 1424
            N +G   P +   +  V
Sbjct: 8901 NKFGCGPPVEIGPILAV 8917



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)

Query: 1700 AVRAIGRLSSMAMIS--GLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK 1757
            A  A+G++SS A +S  G S  + +T +    ++      +E + Q             K
Sbjct: 3372 ASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQ-------------K 3418

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1816
            P F + +  L V  G   RF  ++ G P PE+ WF + Q I  ++     ++E  G   +
Sbjct: 3419 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 3478

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +I D   +   +Y+CKA NS GEATC A L V
Sbjct: 3479 LIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             +D P PPA    A D   SS+TL W    YDGGSAV  Y +EI     + W  ++T    
Sbjct: 20792 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20850

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             R+T + V +L P   Y FRV A+N  G  EP + +E     +  E P+ +++V+
Sbjct: 20851 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20904



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)

Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
            P T  W++  K   +    +V+   N  K             + +L EN  G  +   + 
Sbjct: 7552 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7600

Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
              + + D  DPP   G P   D+  +S+ L+W    +DGG+ ++SY IE+  +    W  
Sbjct: 7601 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7660

Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
            +A    +T   +  L+   EY FRVRA+N  G SEPS+ S+     EK  P  P   +EV
Sbjct: 7661 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7720



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+  +VA +   ++S+SV  + V+++     P F+   +N+ IKEG+  + + R  G P 
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538

Query: 62   PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P + W +N   I      +  ++ G +G  +L I +   +D   YT  A N +G      
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597

Query: 120  ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
            ++ VE  FA+   +  +    G       +AP +E     +G              +  P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657

Query: 162  KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             F  KL  + +K      F C++T  G P   V WL    PL+ + R+ +  + G   L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
                   D G+ TC   N  G    SA L ++      +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)

Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
            SE +GT P F +++ +  ++ G    L   V   P   I W  NG  L  +       +G
Sbjct: 3575 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3634

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               S+ I     ED G Y C+A ND G+  CS  + +       N+K    K        
Sbjct: 3635 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3680

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
                 TE+++ V K       P    PP  ++  +  +   G        V G    T T
Sbjct: 3681 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3732

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
            W K  KQ+  S +  + ++ NGS   I+   ++E  G Y    EN LG       L V+ 
Sbjct: 3733 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3792

Query: 1330 KPDPPAGTPC 1339
            +      TPC
Sbjct: 3793 EDTDMTDTPC 3802



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V V  G  + L+      P  +I W  +G  LK ++F+  S+  +  ++SI+ A  E  G
Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21260

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y  +  N        C++ V   P +  T  P  K + P                    
Sbjct: 21261 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21291

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
                           I+F E +     +SV L   V    G   ITC  ++ R+  Q +  
Sbjct: 21292 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21333

Query: 1284  MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
             M   + +    K+  L    E+   + +  EN+ G  Q  V+  +V K     P PP G 
Sbjct: 21334 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21390

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
             P   ++ S  ++L+W    YDGGS V  + +E  +  +  W+++ T       +    L+
Sbjct: 21391 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21450

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
                +Y+FRV A N  G S PS  S+  T+   P +P    +  D       V   T+T+ 
Sbjct: 21451 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21502

Query: 1456  TEQKVSD------FYDIEERLGSGKF 1475
                 + D       Y IE+R G+ ++
Sbjct: 21503 WNPPLRDGGSKIVGYSIEKRQGNERW 21528



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+V   A + I+   L+V    +D         F +P +++ + E   A+FE  +    E
Sbjct: 5092 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5140

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W +    I S  +F +    +    LVI+    +D G YT E              
Sbjct: 5141 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5185

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
             VEG            K    R     +            KF + L    VKEG+   F 
Sbjct: 5186 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5222

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C+++   +  V W K +  L  S  V +S +     LE+  V  DD+      V     +
Sbjct: 5223 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5277

Query: 242  ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
             S +A+L +   D      + +  A   D       V K+V     K+            
Sbjct: 5278 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5337

Query: 284  KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
            K D L    K K      +G      G+    AN   +  R  K+E     P    +  V
Sbjct: 5338 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5392

Query: 338  LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
             +     I L    V  + +  G  + +    E               Q G+ + +V  +
Sbjct: 5393 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5451

Query: 398  AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
            AAN +      +    P     P S  +V E    KF CEVS  PK    W L+GT    
Sbjct: 5452 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5508

Query: 457  QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
             +   E+ +D   H + +  A   D   Y   A +              +L +  +   F
Sbjct: 5509 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5559

Query: 517  SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
             + LKD    E +  V    +    + R+ W  N Q +   RS        + +QD    
Sbjct: 5560 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5610

Query: 577  DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
               T+  L+ +   Q+   A            SE  L V       P F   L D   ++
Sbjct: 5611 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5659

Query: 637  GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
              +V +  ++S    P V W  +G EI+ S++   +  G +  L +++    D G YTC+
Sbjct: 5660 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5718

Query: 697  AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
                 G  +T   L +++     +   +    SV     ++      I+ D     +W  
Sbjct: 5719 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5769

Query: 757  DGKALCKDTGHFEVLQNEDVFTLVL 781
             G+AL + T   E+ +   + +LVL
Sbjct: 5770 KGEALLQ-TPDCEIKEEGKIHSLVL 5793



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L  + V  G K+ L   V+  P   I WT     LK  K I +       +V+I  +   
Sbjct: 7325 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7384

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y   A N  G+A    +V V D P                   PP     +D T +
Sbjct: 7385 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7426

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                   PP+     +I  +  +++    E                 W K    ++++  
Sbjct: 7427 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7470

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
                      K T L   +E+   + +  EN  G     Q + +T   + DPP G P   
Sbjct: 7471 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7517

Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
              SDI   ++TL+W     DGGS +  Y +E  D     W        + T++ V+ L  
Sbjct: 7518 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7577

Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              +Y+FRV A N+ G  +PS+ +E   + +  + P
Sbjct: 7578 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7612



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
            P F++ ++ + V+EGS A F+  I G+P PEV WF+D Q I  S     QI +  DG   
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L I  V   +  +Y+ KA N  G+AT TAEL+V+
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 59/236 (25%), Positives = 92/236 (38%), Gaps = 24/236 (10%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            PA    LQD   +EG+    QC+VS      + W    K +K ++F  ++Q      + I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD-APASENTKAPEMKSRRPKSSLPPVLGT 1216
             +A PED G Y  VA N  GQ   +  ++++  +   ENT   +                
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWH-------------V 3404

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                + KK+P           P  IQ     +V  GE+V    +V+G       W   ++
Sbjct: 3405 SLSVSFKKEP-------LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQ 3457

Query: 1277 QIQESEHM--KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             I  ++ +    E S   + + I+ A  EH G Y+    N  G       LTV  K
Sbjct: 3458 LILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPK 3513



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)

Query: 1217  ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
             ESD  V + P      P TP   A+    +     + V  G S  +   +   +  +  W
Sbjct: 17038 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17097

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
              K  K I      K +N E G +             + +  EN +G  +A  N       
Sbjct: 17098 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17146

Query: 1332  DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
             DP  P GTP    ++ + +TL W    YDGGS +  Y +E  D  +  W + +      T
Sbjct: 17147 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17206

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
              F V  L  D  Y+FRV A N  G  S+PS  +   T  ++ E P        +D + V+
Sbjct: 17207 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17266

Query: 1439  DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
               +    E D     + T + +    +IEE          F+  L+ K   ++  G++  
Sbjct: 17267 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17326

Query: 1496  KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
             +A +    ++    + +++    P+  VQ      EK ++     +  GG      + E 
Sbjct: 17327 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17386

Query: 1555  FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
              E       +   E +    +++   EG EY+ +            IM VNK G
Sbjct: 17387 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17428



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
             GC   Y +  EN  G         ++   DP     P   P   D   +++T++W    +
Sbjct: 19678 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19737

Query: 1358  DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             DGG+ +  Y++E   S +  WK  + + R T + +  L    EY FRV+++N  G S+PS
Sbjct: 19738 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19797

Query: 1417  QESELTTVGEKPEEPKDEVE 1436
               S+     E+ EEP  +++
Sbjct: 19798 DSSDPQIAKEREEEPLFDID 19817



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)

Query: 263   ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
             E     S  ++EVT +   E + +  + A +  + S+ +     R  SP +         
Sbjct: 25857 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25916

Query: 311   --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
                S+PQP  E + ++ + SP     TP                +  PR+P     SP  
Sbjct: 25917 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 25951

Query: 369   EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
              ER      R A F   +R   + +     K + R+  +  Q+       P+   + +S 
Sbjct: 25952 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 26011

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              V   Q  +F   V   P  EV W+  G  ++ +   I     +G   L +L   T DSG
Sbjct: 26012 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 26070

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
             TY    +N +G+ S   TL V                       G D+    S R    V
Sbjct: 26071 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 26108

Query: 543   PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
             PR  +    +   YA S+       EA  +   ++  + E   + +    +A  ++  +A
Sbjct: 26109 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26168

Query: 597   WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
                 ++ EK ++RK +  L        A   L     + V +G     +    G P P V
Sbjct: 26169 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220

Query: 655   IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
              WL  G  +  S          + +  I  V   D G Y+    NS G+   +  LT+Q+
Sbjct: 26221 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26280



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             L  AP   L  R+  +  G   +F   V+  P  +V W+ NG  +    +        G 
Sbjct: 25998 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26056

Query: 89    FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
              +L I   H +D G Y               T + T G               R V  EL
Sbjct: 26057 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26116

Query: 122   TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
             T   ++A    K+  +   S ++ +   +   ETR S+                      
Sbjct: 26117 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26175

Query: 158   ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                           +  TK   + V EG+  RFSC   G P P VTWL+    L  SAR 
Sbjct: 26176 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26235

Query: 208   SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
              V+        EI  V   D G Y+ +V N  GK      L+IQ      ++ V E KA 
Sbjct: 26236 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26288

Query: 268   NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
              S  R     V S E ++ S EA    K   SP+    P       P   + +  E  + 
Sbjct: 26289 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26339

Query: 328   SPRTAP 333
              P +AP
Sbjct: 26340 LPVSAP 26345



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%)

Query: 444  EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502
            EV W+ E   V   E   +  +D  ++ L + K  T D  G Y C A N  G+ + S  L
Sbjct: 4396 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4454

Query: 503  QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562
             V    V   AP     ++   V  G      C ++  P  R  W   G+ I Y    C 
Sbjct: 4455 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4509

Query: 563  AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
                  ++ L I      D G YTC A N  G VSC+A +TV      +K   LLP    
Sbjct: 4510 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4569

Query: 619  KPTAPIFLQGL 629
            +P   + L+ +
Sbjct: 4570 EPKEEVVLKSV 4580



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)

Query: 1098  PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
             P    KL  V  V  G  + L+  V   P   + WT +      T+   + +        
Sbjct: 11829 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11888

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
              S+ KA   D G Y   A N AG       V V D P    N K  ++ S R        
Sbjct: 11889 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11940

Query: 1214  LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                    TV   P P+      +   I++  E +++                     W  
Sbjct: 11941 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11973

Query: 1274  FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
             +   +             G+ +T L    E+   + +  ENK+G+     +  V+ K   
Sbjct: 11974 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12021

Query: 1331  -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
                  PDPP  T  + +     +T+ W    YDGG ++  Y +E  +  +  W  +  + 
Sbjct: 12022 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12077

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                    VQ+LLPDHEY+FRV+A N  G  EPS  S    V + P EP
Sbjct: 12078 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12124



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ +      +V   ++L +       P AT+ W  +G+TLK T  + +S   ++ S+SI
Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19082

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++A  ED G Y+    N AG       + V D P                   PP     
Sbjct: 19083 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19124

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              + +         PP+     QI  +  ++K                +  + TW    + 
Sbjct: 19125 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19168

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
             +  +  +K+     GS+             + +  EN+ G      +  VV +    P  
Sbjct: 19169 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19216

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
             P GTP       S++ ++W     DGGS V  Y +E       +W  ANK          
Sbjct: 19217 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19271

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
             T   V  L     Y++RV A N+ G  + S+  E       P +P  + EV++   K   
Sbjct: 19272 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19330

Query: 1447  VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
             + +     +   K++ +      L  G++
Sbjct: 19331 LKWSKPHYDGGAKITGYIVERRELPDGRW 19359



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)

Query: 1091  SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
             S+    APAF  + +  ++ EG+ +L  C++S +P   I W  N   +  +  + +S+  
Sbjct: 26755 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26814

Query: 1151  SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
             ++ S+ I  A   D G Y   AKN  GQ   +  + V    + P+ E             
Sbjct: 26815 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26874

Query: 1195  --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
               ++++ +M + + ++S      + + +  + K A  +    +                 
Sbjct: 26875 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26934

Query: 1236  --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
                                 +PP+I   P D  +  G+ + +    TG      TW    
Sbjct: 26935 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26994

Query: 1276  KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             ++I  QE     +EN+++ + L I+  +++  G YTL + N+ GS  A VN+ +
Sbjct: 26995 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
            S +  S A L   AE  P   P F + ++ + V +GS  R   ++ G P P V +++D  
Sbjct: 86   SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142

Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I+ S  FQI  + D   SL+I++   +D   Y+  A NS+G AT TAEL+V+  EE
Sbjct: 143  EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
            P   Q+LQ V V  GK       +S  P   I W    + L T    KF+   QE +L  
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            +   +A PED  +Y C AKND G A  S  ++V+          PE+ S  P   +P   
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP II   +D     G+      +V+GT  +  +W   
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             K+I+ S   ++   E+  +L I  A  E  G YT +  N +G   +  NL++
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)

Query: 1104  LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
             ++ + V  G  +     +   P  T  WT +G  +KT +   +  +     ++I+  L  
Sbjct: 11145 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11204

Query: 1164  DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             D G Y+    N AG    +  +TV D P              P   +  +  T    T+ 
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11252

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P    P      P I    E Q  R     + +G V+                     
Sbjct: 11253 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11283

Query: 1284  MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
                    +GS  T L       GC   + +  ENK+G      +   V K    P  P G
Sbjct: 11284 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11336

Query: 1337  TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
              P  +DI  ++ T+SW     DGGS +  Y +E       W   NKT           F 
Sbjct: 11337 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11391

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             V  L   + Y+FRV A N+ G S+PS  S+
Sbjct: 11392 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11421



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + L   V   P  T+ W  +G  LK  + I ++ + +LC++ +     +D G Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
                A+N +G    + ++ V D P    + K  +M S R   S  P L   G+E    +  
Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13054

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             K     P  A                         +V+ T PIT   ++  K I+  E+ 
Sbjct: 13055 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13087

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
                                    + +  ENK G          + K   DPP     P  
Sbjct: 13088 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13124

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
             S+I    +T+SW   + DGGS +  Y +E  ++    W ++        +     L    
Sbjct: 13125 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13184

Query: 1399  EYKFRVRAINVYGTSEPSQESE 1420
             EY+FRV AIN  G  +PS  S+
Sbjct: 13185 EYEFRVTAINKAGPGKPSDASK 13206



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)

Query: 1083  GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
             G +D    S+ Q      ++ L D+     K L+++   S          P   ++W+  
Sbjct: 19792 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19851

Query: 1135  GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
                L+T  ++  +   S  S++IE A   D G Y    +N    A  +  V V D P   
Sbjct: 19852 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19907

Query: 1195  NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
                             PP   T  D T +          A +   +   PE+        
Sbjct: 19908 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19932

Query: 1255  VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
                     G  P+    ++ R   + S+   V  + N ++L+      +    Y   V  
Sbjct: 19933 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19981

Query: 1313  ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             EN+ G     + +  + + +KP PP      S I   S++L+W    +DGGS +  Y +E
Sbjct: 19982 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20040

Query: 1370  IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
               +   K W + A  +ST   V  L  + EY FRV A N  G S+P +      + E+ E
Sbjct: 20041 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20100

Query: 1430  EPKDEVE 1436
              P+ +++
Sbjct: 20101 PPEIDMK 20107



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            + +  GK L +   V+  P  T +WT     L   + +++   G+   + I+ AL +D G
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8800

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
             Y   A N  G    + +V V D P              P   L PV+ T     +    
Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8846

Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P+    + +   II+  +D K+            T  QPI            E+E  K 
Sbjct: 8847 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8882

Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
            +       +T L   QE+   + ++ +NK G     ++  +  VD   PP        ++
Sbjct: 8883 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8933

Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
               S++TL W     +GGS +Q Y IE        ++ +    C +TSF V++L     Y
Sbjct: 8934 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8993

Query: 1401 KFRVRAINVYGTSEPS 1416
            +FRV+A+N  G SEPS
Sbjct: 8994 EFRVKAVNEIGESEPS 9009



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G+   L+  VS  PP T+ W+ +GK L+ T  + +       ++  + +   D G Y   
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15163

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A N  G A+    V V D P              P      V    S+  V     P   
Sbjct: 15164 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15210

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I+Q  E  ++                     W     ++Q ++         
Sbjct: 15211 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15241

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
               K+T L    E+   + ++  NK G  +   +  V+       PDPP   P  + I   
Sbjct: 15242 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15297

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ + W     DGGS + +Y +E  D A + W +    T     + V  L   HEY+FR+
Sbjct: 15298 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15357

Query: 1405  RAINVYGTSEPSQES 1419
              A N  G S PS  S
Sbjct: 15358 MAENAAGISAPSPTS 15372



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +L EN+ G     +   ++   ++P PP G     D+  +S++LSW    +
Sbjct: 15644 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15702

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             DGGS +  Y +E+    +  W   AT + T   +  L+   EY FRV A N  G S+P Q
Sbjct: 15703 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15762

Query: 1418  ES 1419
              S
Sbjct: 15763 LS 15764



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PP+  P   D    S++L+W    YDGG+ +  Y +E+ +     W  +   AT R+T
Sbjct: 22970 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23028

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
              F V DL    +Y FRV A+NV G SE S+        E+ E P  ++E++DD +K
Sbjct: 23029 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23082



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
             +AP F    RNL ++  + A    +V G+P+P V W+R G+ I + G ++ +     G  
Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24613

Query: 90    SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
              L+I +V ++D   Y   ATN  G+   T  L VE      L                  
Sbjct: 24614 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24655

Query: 150   ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
                        PK    +G V    G++       +G+P P +TW KG   +  +    V
Sbjct: 24656 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24704

Query: 210   SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
                     L   +GV + D G Y     N  G    + EL +  +    R          
Sbjct: 24705 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24758

Query: 269   SDVRKEVTNVISKESKLD 286
             SDV ++  N+   E   D
Sbjct: 24759 SDVSRDSVNLTWTEPASD 24776



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ K       +  G+ L ++  V   P   I W  +G+ LK T  + + +  +   + I
Sbjct: 17940 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17999

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y   A N AG A  +  V V + P                   PPV    
Sbjct: 18000 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18041

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  +         PP      QI  +  +++                   T TW     
Sbjct: 18042 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18085

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
              +  +  +K+   + G++             + +  EN+ G      +  V+      +P
Sbjct: 18086 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18133

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
              PP GTP  + I    + + W+    DGG+ +  Y +E  +  +  W +L     + T F
Sbjct: 18134 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18192

Query: 1390  NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 L    EY+F+V A N+ G  +PS+ SE     +  + P
Sbjct: 18193 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18234



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)

Query: 9     SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
             S+ + + SL  + S    +  T A   +  PR++ + EG +A+F     G P P VTW R
Sbjct: 26166 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26224

Query: 69    NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
              GQ +++  R  +     + TF   I +V   D G Y+    N  G ++    LT++ + 
Sbjct: 26225 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26282

Query: 127   -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
                K +  P   K+   R  +P                       ET+P+       +  
Sbjct: 26283 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
               PPK    L     KE  + + +C +        +VTW K    L+ +         +G
Sbjct: 26343 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26400

Query: 215   MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
                L+I+ + + D G Y C +    G +  + +   Q   S +    + ++   SD +  
Sbjct: 26401 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26460

Query: 275   VTNVISK 281
              + V  K
Sbjct: 26461 ESTVTRK 26467



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G+++ +  +V G      TW K  K +   + + +       +L I  A +   G Y
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11607

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              +  +N  G  Q    + V+D+P P       +++   + T+SW     +GGS + ++ +
Sbjct: 11608 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11666

Query: 1369  EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
             E      K W  +A+  +      +LL ++EY FRV A N  G   P+ E++   +    
Sbjct: 11667 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11725

Query: 1426  -EKPEEPKD 1433
              ++P EP++
Sbjct: 11726 IDRPGEPEN 11734



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)

Query: 1215  GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
             G +S+  V + P   P  PP    PP I+    D       SV L     K TG  PIT 
Sbjct: 13789 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13837

Query: 1270  TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               ++F  R  +      K        K+T L    E+   + ++  N  G  +  +    
Sbjct: 13838 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13895

Query: 1328  VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
             V   DP  P G P   +I  +S+TL W    YDGG  +  Y +E  D  +K+W +     
Sbjct: 13896 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13955

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
                 +F V DL+   +Y+FR+RA N  G  S PS+ +E     ++ E P
Sbjct: 13956 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +  EN+ G     Q    + V + P PP G     D+  +S++LSW    +
Sbjct: 16726 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16784

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             DGGS +  Y +E+    ++ W E A  +S    + +L    EY FRV A+N  G S+P
Sbjct: 16785 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16842



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
             S+ TV + P  K P     P   +   +  +V+  E +   G +V G      +  +  W
Sbjct: 15957 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16015

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +K  K        K    E G +     + +   G         +G         V   P
Sbjct: 16016 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16066

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
               P G P A  +  +S+TL W   +YDGGS +  Y +E  +     W + +      T F
Sbjct: 16067 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16126

Query: 1390  NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
              V  L+ DH Y+FRV A N  G  SEPS+ +   T  ++ + P+
Sbjct: 16127 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16170



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L+  +S  P  TI W  + K L+T   + +     L S+ I+ A   + G Y+  
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20574

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G A  + +V + D P              P   +     T    T+  +P P   
Sbjct: 20575 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20621

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I++  E  +V                     W         SEH++    E 
Sbjct: 20622 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20651

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
                 T +    E+   + +   NK G  +   + +VV K     P PP G P  + I  +
Sbjct: 20652 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20708

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+ W     DGGS +  Y +E  D  +  W ++   T R T   V  L  + +Y++RV
Sbjct: 20709 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768

Query: 1405  RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
              A+N  G    S+ SE     +   P  P  ++ ++D
Sbjct: 20769 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20805



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 33/95 (34%), Positives = 48/95 (50%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P   + I+   V +GS A F  ++ G PDPE  W+K+   I  S      + ED  C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            I DV  +D A    KA+N  GE +  A L+V+  +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
            P  P   P   D   SS++L W   + DGGS ++ Y +E+ +     WK        + T
Sbjct: 9332 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9391

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
            C     N+++L    +Y+FRV+A+N  G SEPS  +      +  EEP+  +++   D
Sbjct: 9392 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9446



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
             + KP PP   P A D   +S+ L+W    +DGGS +  Y +E     ++ W+       +
Sbjct: 10738 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10796

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
             C  T + V  L     YKFRV A+N  G S+P+   E   V ++ E P+
Sbjct: 10797 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10845



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)

Query: 1006  KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
             K V +S PLS   P   L+     K + TL           L P+  G AK D  + S  
Sbjct: 12416 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12466

Query: 1064  KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
             +EE   D   + +  +  +    G  + +K                 E++G   A +Q L
Sbjct: 12467 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12526

Query: 1105  -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
                    + + +  GKKL ++  V   P  T  W      + T+  + + +  S   + I
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12586

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
             +    +D G Y   A+N +G      +V V DAP                   PP  +  
Sbjct: 12587 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12631

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
              ++DA       P     + +   I+   E   V  G+ V     VT T        +  
Sbjct: 12632 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12682

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
             K I   E++    +EN              G    L   K+    AQ    V  +P    
Sbjct: 12683 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12727

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
              T    D     + ++W     DGGS +  Y IE       +W  AN T       RST 
Sbjct: 12728 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12778

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
             +    L+   EY FR+ A+N  G+S PS+ +E  T    P +P  + EV D
Sbjct: 12779 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12828



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)

Query: 45    KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +EG   K+  ++  Y +  QVTW+   + + +  ++ +     G   L +  + + D G 
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25266

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
             Y C+  N  G      EL V+G   +++      +T+  +      +T   +  E PP+F
Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25320

Query: 164   ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
                L       G+  RF   IT  P+P VTW K    ++P     + +     G+  L I
Sbjct: 25321 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25380

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             + V  DD   YT +  N  G+ S  A+L++
Sbjct: 25381 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)

Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
            D EK+ +     P FK+KL  + +        +C+++   DP   + W  +GK L+    
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
            + +  E   CS+    A   D G+  C A N  G    S  + V D    E +   E + 
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760

Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
               +  L  +   E  A         T  K    P I+ +PE  +V  GE+     +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820

Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
                   W    + I++S+  +V   +    L I+  +    G   +  EN  G  + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879

Query: 1324 NLTVVDKPD 1332
             L +  + D
Sbjct: 1880 KLEIQQRED 1888



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
             KP PP   P   DI  SS+ LSW    YDGG  +Q Y +E  D +   W           
Sbjct: 16465 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16523

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             T+  V+ LL  HEY FR+ AIN  G  E +       V EK E P  ++++
Sbjct: 16524 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16574



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R    I GRP P+VTW K N+ L+  A +  +E     +L I   N+ D G
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14471

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
              +   + N +GK   S  ++++ LD+      +R T  T   V              +TN
Sbjct: 14472 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14529

Query: 278   VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
              I ++   ++     A  K   C+    G S          A N     +P   ++    
Sbjct: 14530 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14589

Query: 326   KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
              ++P       ++  T S+++L      P+P+  G   ++    E +R    +  T  T 
Sbjct: 14590 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14644

Query: 386   QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
               GL               Q +   +A R  P E      +  +  P+ + +   Q++  
Sbjct: 14645 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14704

Query: 426   -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
              K    +K    V G PKP V W  +G  + +Q   +     A S  L + +    DSG 
Sbjct: 14705 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14763

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
             Y  TA N  G++    T+QV  +      P  F  V  D
Sbjct: 14764 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14802



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
             AP     +KD     G+   L C + G P+P I W   G+ +  +R    + +     L 
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219

Query: 570   IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
             +     ED G YTC+A N +G+V  S             S+ LL   P   P  P+  + 
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24266

Query: 629   LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
                +    GS + + V   G P P + W H    +Q SE+   E       L ++ V  +
Sbjct: 24267 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24322

Query: 689   -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
                G Y  +  N  G V   A+L V+      +P   + P  + A L  S +IS
Sbjct: 24323 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24371



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            PP   + L  V V EG+     C I+G P P VTW + +  ++ S    ++ ++G+  L 
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            I     +D G +TC  VN +G  S S  L++Q     +  F +ET A        VT   
Sbjct: 956  IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003

Query: 280  SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
            + E K  ++S +      + +  Q G   P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
             +++      + V +       TI    + H   + ++ +NK G       + +    +  
Sbjct: 9884  KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
              P  P   P  S +  +S+T++W    YDGGS V  Y +E+ D+ +K WK +      A 
Sbjct: 9944  VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10002

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 S+ V  L+   +Y+FRV AIN  G    S  S+  T  +    P
Sbjct: 10003 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10050



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             + V  G+ + +  +V   P   I WT  GK L   K + L Q+     + I++A+  D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y   AKN +G A+ S  V V D P              P  +L     T+ + T+    
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11649

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                            + P D                G   IT   +++RK  Q+   +  
Sbjct: 11650 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11680

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
              +         L A  E+   + +  ENK+G      ++   + +  +D+P  P     A
Sbjct: 11681 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11738

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
              D   + + L W    YDGGS   SY +E     +  W+ +   + + T + V   + + 
Sbjct: 11739 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11797

Query: 1399  EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
              Y+FRV+  N  G S+  +  E+  V E  ++P  ++++S
Sbjct: 11798 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11836



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
            T+  E   +++   P F Q+LQ + V +G ++ LQ +V+  P   + +  +G  ++++  
Sbjct: 90   TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
              +SQEG L S+ I +A PED G Y   A N  G+A  + ++ V   ++ PA +      
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
              +  E +  R +  +       S ATV+             K  P+ PPK    +  PP
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269

Query: 1239 QI 1240
             I
Sbjct: 270  SI 271



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            KP F       + +EG  ARFD K+ G P PE  WF D Q I      ++   EDG  SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            II      D  ++T  A N  G ++ +  L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)

Query: 1308  YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
             + ++ EN  G  +       +  +D  DPP G P   +I   ++TL W    Y GG  + 
Sbjct: 14959 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15017

Query: 1365  SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
             SY +E  D  N  W     +      F V  L  D  Y+FRV A N  G  S PS+ S+ 
Sbjct: 15018 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15077

Query: 1422  TTVGEKPEEPKDEVEVSDDD 1441
              T  +  E PK +V+V   D
Sbjct: 15078 ITCRDDVEAPKIKVDVKFKD 15097



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PAFK       V  G+ L +       P   + W  +   LK T  +      +   ++I
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15835

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A  ED G Y     N AG+A  +  V V D P                   PP    +
Sbjct: 15836 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15877

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  T         PP               K   G S+  +  V      T TW     
Sbjct: 15878 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15919

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
                         S   ++ TI A R +  GC   + +  EN+ G S       TV   P 
Sbjct: 15920 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15966

Query: 1332  --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
                 P GTP  +     S+ + W     DGGS V  Y +E  +  +  W +L       T
Sbjct: 15967 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16026

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F    L    EY+FRV A N+ G  +PS+ SE   V   P +P    E          +
Sbjct: 16027 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16085

Query: 1448  DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
              ++  T +   K++ +   ++ L  G++
Sbjct: 16086 QWKKPTYDGGSKITGYIVEKKELPEGRW 16113



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P +K  +  VH  E  K+     +   P  TI W    + L  T  + +       S+S+
Sbjct: 16175 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16231

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A+  D G Y   AKN AG+   +  V V D P       PE          P V+   
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16274

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
             S  T +K      PP       II +  +++    E+  L   V     Q ++C      
Sbjct: 16275 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16324

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
                      KV     G++ T           + ++  NK G  +   +  VV K     
Sbjct: 16325 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16364

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
             PD P   P  + +   S+ + W   + DGGS +  Y +E  D     W            
Sbjct: 16365 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16423

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
               V  L+ +H+Y+FRV A N  G SEPS  S
Sbjct: 16424 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16454



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W+K  K   +    K    + G +     + +   G         +G         V   
Sbjct: 18179 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18229

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
             P  P G P A  I  +++TL W   +YDGGS +  Y +E  D  +  W +        T 
Sbjct: 18230 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18289

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
             F V  L+ D  Y+FRV A N  G  SEPS  S   T  ++ + P   ++
Sbjct: 18290 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18338



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
             AQ+  TV D P    G P  S+I  +S+TL+W     DGGS +Q Y +E  +  +  W +
Sbjct: 21773 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21828

Query: 1381  LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
             + + R    T F V  L   +EY+F V A N  G    S  S L    E   P  P   V
Sbjct: 21829 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21888

Query: 1436  EVSDDDEKEPEVDY 1449
             +V+D  +    +++
Sbjct: 21889 KVTDTSKTTVSLEW 21902



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
             P  P   P  +D   SS++L+W    YDGG+ V+ Y +E+ ++A   W    TC      
Sbjct: 18630 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18686

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
             +   F V  L  + EY FR+ AIN  G  EP+         E+ E P+ E++
Sbjct: 18687 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18738



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             +HV  G+ + L   ++  PP    W   G  L+ ++ + +     +  ++I +    D G
Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23435

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
              Y    KN  G    + +V + D P                    P+   E DAT   + 
Sbjct: 23436 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23480

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P P+    A +   +++  +  +          G +  ++ +T +  KF +  + +E+
Sbjct: 23481 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23530

Query: 1284  MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             +            + A  +   G Y   +++++   ++ + +     P PP  T    D+
Sbjct: 23531 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23571

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
                 +TL+WY    DGGS V  Y +E        W   NK    +   RST      L  
Sbjct: 23572 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23626

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
               EY+ RV AIN  G+ +PS+ S+     +      KP+ P+
Sbjct: 23627 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23668



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PPA  P   D   SS++LSW   +YDGGS +  Y +E+  + +  W         + T
Sbjct: 13217 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13275

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
              F V  L+ D +Y+FRV A+N  G S+PS
Sbjct: 13276 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13304



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)

Query: 1325  LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
             +   ++P PP       D   SS  L+W    +DGGS +  Y +E+    +  W E    
Sbjct: 22168 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22226

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
             +  +F V+ L+   EY+FRV+A N  G SEP +      + E   EP
Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22273



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P    + +    K  +  +  C++ G P P++ W+  G  +  Q    ++  D  +H L 
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24219

Query: 474   LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             ++     D G Y+C A+N  G++  S  L ++  A  +  P +    K    + G    L
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24276

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
                  G PVP +TW    + +Q + + T E      H+  ++   + H G Y     N  
Sbjct: 24277 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336

Query: 590   GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
             G V     V + +K             P KPT PI ++ L          +  +  +S  
Sbjct: 24337 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24373

Query: 650   PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
             PP +    W+ N      E +E  ++         + C      E+ G Y    A N+ G
Sbjct: 24374 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24433

Query: 703   ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
                 +   +V+ ++ P +  +P    KP ++TA        SC +A  P
Sbjct: 24434 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24475



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 28    PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
             P++  P  +   ++  +   + AKF  +  G P P   W ++G+ IT GG++ L    +G
Sbjct: 26475 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26533

Query: 88    TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
              F L IH     D G YTC   N +G+   + +LT++
Sbjct: 26534 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26570



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
             V KP PP G P   D   SS++++W    YDGGS +  Y +EI       W+ +   A  
Sbjct: 15381 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15439

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             ++TS+ +  L  + EYK R+ A+N  G  EP+
Sbjct: 15440 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15471



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W K  K +     MKV   + G               Y +  EN  G  +   +   V  
Sbjct: 19261 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19309

Query: 1331  PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
              DP  P G P  ++I   S++L W    YDGG+ +  Y +E  +  +  W +      + 
Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19369

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
             T F V +L  D  Y+FRV A N     SEPS+ +    V +  E P+  ++V   D
Sbjct: 19370 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19425



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            EK    P F K + + ++  G  A     + G P P++ WF +   +  S  ++  +D D
Sbjct: 3576 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3635

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
             + SLII     +D+ +YTC A N  G+  C+A L + +  EG  + E E
Sbjct: 3636 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3684



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 2/105 (1%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            +E P   P     ++D    EG  ARF C++ G  D +V W+  D+ I+ SR F++   E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
            D    L I++   +D+  YT  A N++G+ + TA L +E   + E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFE 3394



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%)

Query: 405  MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
            ++ + DS     + +P ++   E++ +    EVS         +L+ TPV +   S  V 
Sbjct: 4265 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4324

Query: 465  EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
            ++     L   + +  +S + S T   A  ++      + E   + E  P   + L D  
Sbjct: 4325 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4378

Query: 525  VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580
              EG    L  S+  T    + W    + +   +  +   +     L I     EDH G 
Sbjct: 4379 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4436

Query: 581  YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
            Y C A N  G+ + SA +TV                  K  AP+  + +  L+V  G   
Sbjct: 4437 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4479

Query: 641  TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              T ++   P     W   G EI ES+           SL I      D G YTC+A N 
Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4539

Query: 701  AGEVRTQAVLTVQEP 715
             G V   A LTV  P
Sbjct: 4540 YGSVSCTATLTVTVP 4554



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)

Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
            W     T+K TK  +    EGSL              +++  A+N  GQ++ +    ++D
Sbjct: 7758 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7801

Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
            +  +++T           +  PP      D T +       PPK      I ++  ++K 
Sbjct: 7802 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7852

Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
            R G                  W+K  K      + +V +   G+++      +   G   
Sbjct: 7853 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7893

Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
                  +G       +  ++ P  P   P     +D     + ++W     +GGS +  Y
Sbjct: 7894 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7947

Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E+     + W  + +   +   F V++ ++PD EY  RVRA+N  G SEPS+ SE   
Sbjct: 7948 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8007

Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
              +   +P  ++E  D    E E     V +R V + T
Sbjct: 8008 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8045



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G+   L+  V   P  TI W    K ++ +    +        + ++ A+  D G Y
Sbjct: 17265 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17324

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
                A N AG       V V D P              P      V G  S+    K    
Sbjct: 17325 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17367

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              +PP       I  +  +++    E+  L   V  ++ +T                    
Sbjct: 17368 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17403

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
               N  K+T L    E+   + ++  NK G  +   +  V+ K     P PP      ++I
Sbjct: 17404 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17458

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
                S+T+ W     DGGS +  Y +E  D +   W +    R T     V  L  DHEY+
Sbjct: 17459 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17518

Query: 1402  FRVRAINVYGTSEPS 1416
             FRV A N  G  EPS
Sbjct: 17519 FRVSAENAAGVGEPS 17533



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E +  +F C ++   +  V W  +G  + +     ++  D   H L +  ++  D G 
Sbjct: 5125 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5181

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+   +  +G+ + +      RL V  +   F S L+D  V EG+     C +    +  
Sbjct: 5182 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5231

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
            + W  N   +  +R+   +   + H  +           + E  L  +S      V E  
Sbjct: 5232 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5279

Query: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
            S+ + + L          P F   L D   ++  ++T+  +VS + P  V W  +G EI 
Sbjct: 5280 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5330

Query: 665  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
             S  +  +  G +  L I++   +D G Y C+     G  +T+A +TV+      +   +
Sbjct: 5331 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5381

Query: 725  SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
             KP   V   +G++      ++    P VH  W   G+ L   +   E++++     L+L
Sbjct: 5382 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5437

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
               Q    G+      N     + +V       +   S  +   +          REP +
Sbjct: 5438 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5497

Query: 828  CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
               L G     +  G DR+  ++ G   +    ++    ED    +    +  +HT    
Sbjct: 5498 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5550

Query: 885  --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
              E IR + +  L  +D+  K+    V T  LS D+++      + +  N QR    ++V
Sbjct: 5551 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5602

Query: 939  S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
            S ++E K HS   + F+  L+   TS+  V                 +  + KL    G 
Sbjct: 5603 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5645

Query: 998  S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
               + +  +   VE  + +   + S    PV   K  + +KP  NA              
Sbjct: 5646 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5692

Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
               +K+  K+    LKK +K+D+       GT     + + +       + L  V V E 
Sbjct: 5693 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5749

Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            +    + ++S D      W L G+ L  T    + +EG + S+ +     +  G
Sbjct: 5750 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5802



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)

Query: 1090  RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
             R E      +   K +DV V   G+  +L+  +   P   ++W+ +GK L+ T   + + 
Sbjct: 18327 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18386

Query: 1148  QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
                   ++ ++  +  D G Y     N  G       V V D P              P 
Sbjct: 18387 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18433

Query: 1208  SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
                  V G  ++        P     A +   II+  E  ++                  
Sbjct: 18434 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18475

Query: 1268  TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               +W +   ++Q   +          K+T L    E+   + ++  NK G  +   +  V
Sbjct: 18476 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18521

Query: 1328  VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
                   KP  P  TP  S I   S+ ++W     DGG+ ++ Y +E  D     W +   
Sbjct: 18522 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18581

Query: 1382  ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
              T       V  L   H Y+FRV A N  G  EPS+ S
Sbjct: 18582 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18619



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
             EAP      +++  K G  A+   ++ G P P + W+R G+ +    ++ +    R T +
Sbjct: 24159 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24217

Query: 91    LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
             L +    +ED G YTC ATN  G  + + +L ++ +     G P+  K  G         
Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24268

Query: 151   TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
                                     G   R      GRP P +TW  G   LQ S  +++ 
Sbjct: 24269 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24306

Query: 211   EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
                    L +  V  +   G Y   + N  G      ++ IQ   D      V E    N
Sbjct: 24307 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24366

Query: 269   SDV 271
             S V
Sbjct: 24367 SAV 24369



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
             +KP  P G P  + +   S  ++W   + DGG+ +++Y +E  +     W  + T   R 
Sbjct: 24451 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24509

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
             T F+V++L+   EY+FRV+  N+ G SE S+ SE       P  PK +V +     KE
Sbjct: 24510 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24560



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
             P FK+ L +    EG+ +  + +VS  PP T+ W  +G+ L     I +  EG    ++ 
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482

Query: 1157  IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
             I   LPED G Y+  A N AG   C   + V+      +  K+ E   R  +  +   L 
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25542

Query: 1215  ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
                   GTES            +A V  KPA  T   K     +I +  E++K+R
Sbjct: 25543 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25597



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
            PYF       ++VEG +  F C++ G P P V W K    +     +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +IS    DD  +YT    N  GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + ++ EN+ G       +  V   +PP+  G    +D+  +S +L W    +DGGS V  
Sbjct: 17815 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17874

Query: 1366  YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             Y +E+     + W  +A  +  +  V  L    EY+FRV+A N  G S+P
Sbjct: 17875 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17924



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)

Query: 1739  EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
             ED  +A L       P    ++P F + + + E  EG +  F+ ++ G P P + W KD 
Sbjct: 25401 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460

Query: 1796  QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
             Q +    + +I ++     +L I D   +D   Y   A N+ G  +C A L VE +   +
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520

Query: 1856  GEGEEEEE 1863
              E + +EE
Sbjct: 25521 QEFKSKEE 25528



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
            P   + ++ + V  G  ARF   I G P P++ W+K++Q +  S  F+  +  DG   +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            ++ +   +D A YTC+A N  G AT +A L VE  E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 96/428 (22%), Positives = 149/428 (34%), Gaps = 56/428 (13%)

Query: 1090 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1149
            + E  G  P+F Q L  + V  G+ +    +VS  P   I W  N + +  TK ++   E
Sbjct: 3411 KKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE 3470

Query: 1150 GS--LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV-DDAPAS------ENTKAPE 1200
             S  +  + I  A  E  G Y C A N AG+A C+  +TV   AP S      E     E
Sbjct: 3471 ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEME 3530

Query: 1201 MK----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFP 1244
            MK                +    S +   L   S++ V   P      K    P  I+  
Sbjct: 3531 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEV 3588

Query: 1245 EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEH 1304
             +  +  G+   L   V G       W      +  S   K     +   L IL  + E 
Sbjct: 3589 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLED 3648

Query: 1305 CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY------- 1357
             G YT +  N  G       L +  K +    T   S +  S   L      +       
Sbjct: 3649 EGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKP 3708

Query: 1358 ----DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHE 1399
                 G  A+  Y++    +   TW    K+L T            S +F V D   +  
Sbjct: 3709 IRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDS 3768

Query: 1400 YKFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
              +  +A N+ G S  + E     E T + + P + K   E  +D  + P        ++
Sbjct: 3769 GLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALD 3828

Query: 1456 TEQKVSDF 1463
            +EQ+++ F
Sbjct: 3829 SEQEIATF 3836



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             V KP PP       D   +S+TL+W    YDGGS +  Y +EI  +  + W+ +      
Sbjct: 17545 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17603

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
             R T F +  L    EYK RV A+N  G  E +  S   TV  KPE+  +  E+  D E
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17657



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)

Query: 1302  QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
             QE C  Y  +L  N+ G    A+    V V +P  P G     D+  ++ T+ W     D
Sbjct: 18891 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18950

Query: 1359  GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GGS +  Y +E+    ++ W      ++    +  L    EY FRV A+N  G S+P Q
Sbjct: 18951 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 921  EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978
            E+MD  +  Q+ V+P T  E E K + S ++V + +V ++ K    TPV + V     + 
Sbjct: 4267 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325

Query: 979  P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033
                 S+   ++K  + + S + E    K  E+   L   +  GP+   P+ +    E  
Sbjct: 4326 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4383

Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083
                   + NAK             DE  K    +     V + VN +  H G       
Sbjct: 4384 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4442

Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138
                 T  + K +  +  AP  K+K++ + VA G      C++ S P     W   G+ +
Sbjct: 4443 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4502

Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
              +    +     + S+ I +    D G Y C A N+ G   C+  +TV   P  E    
Sbjct: 4503 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4561

Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
              +  R+P+     VL     + ++K+P    PK  PK     +    PE    +  E V
Sbjct: 4562 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4617

Query: 1256 EL 1257
            E+
Sbjct: 4618 EV 4619



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + +   VS  PP T+ W +N +TL     I  +   S  S+ I+      +G+Y
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10221

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
               +AKN+AG+ + +  V V D P    T  P +       S                   
Sbjct: 10222 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10261

Query: 1229  KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
                       ++  F PED                G  PIT  ++  +++        V 
Sbjct: 10262 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10295

Query: 1288  NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
              +      T+    Q     + +  EN +G      + +A V    +  P+ P       
Sbjct: 10296 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10354

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
             ++  +++TL+W    YDGGS + +Y +E      + + ++      S  + V+ L     
Sbjct: 10355 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10414

Query: 1400  YKFRVRAINVYGTSEPS 1416
             Y++RV A+N+ G  +PS
Sbjct: 10415 YEYRVSAVNIVGQGKPS 10431



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + ++  V   P  T+ W    + LK T+ +      +   ++I + +  D G Y   
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A+N  G+      + V D P                   PP    + D            
Sbjct: 14768 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14798

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                 +    + F  D     G        V   Q  + TW++    +       +  +  
Sbjct: 14799 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14847

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
              ++LT     Q     + +  +N+ G      +  +V       P PP GTP  + +   
Sbjct: 14848 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14901

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+SW+    DGGS +  Y +E  +     W+ +  A      F    L     Y+FRV
Sbjct: 14902 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14961

Query: 1405  RAINVYGTSEPSQESE 1420
              A N+ G S+PS+ SE
Sbjct: 14962 IAENMAGKSKPSKPSE 14977



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)

Query: 1057  ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
             E L   ++ E +   KND        A ++   K  + + TA       Q +    G   
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22293

Query: 1116  LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
              +   +S  P   + W L    LK T  + ++      +++++ ++  D G Y    +N 
Sbjct: 22294 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22353

Query: 1176  AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
             AG    S  V V   P              P +    V    +++ V     PK      
Sbjct: 22354 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +   I++  E                      T  W      ++ ++           K+
Sbjct: 22401 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22430

Query: 1296  TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
             T L    E+   + +  EN+ G S+  +    + + P  P   P   +   + ++++++ 
Sbjct: 22431 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22488

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             W    +DGGS +  Y +E  +     W  +    C   ++ V  L+   EY+FR  A+N 
Sbjct: 22489 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22548

Query: 1410  YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
              G S+ S+ S    + + P +     EV+D
Sbjct: 22549 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22577



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
             P  P   P  +D    S +L+W    YDGG  +  Y +E     ++ W +  T    R T
Sbjct: 14300 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14359

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F V DL    +Y FR+ AIN  G  EP+   ++  V         E E++ D E + E+
Sbjct: 14360 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14410

Query: 1448  DYRTVTINTEQKVSDFYDIEER 1469
               RT+ +     +  F  I+ R
Sbjct: 14411 -RRTLVVRAGLSIRIFVPIKGR 14431



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)

Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
            P      +++E  E ++   A      ++K   KP        + V+EG  ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820

Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
            YP P+V W+ + Q IR+S+ F++ Y  DG   L I D    D  +    A N  G     
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878

Query: 1844 AELIVETMEE 1853
             +L ++  E+
Sbjct: 1879 VKLEIQQRED 1888



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
             GC   + ++ EN+ G  +       V   + P PP       DI  S+++L+W    +DG
Sbjct: 14562 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14620

Query: 1360  GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             GS +  Y IE     +  W  + T +     V++L    EY F+V A+N  G S P +ES
Sbjct: 14621 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14679

Query: 1420  ELTTVGEKPEEPK 1432
                 V E+   P+
Sbjct: 14680 RPVIVKEQTMLPE 14692



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
            AP F Q LQ V V EG     +  +S  P   + W  +G+ + T+    + +S       
Sbjct: 5    APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            ++I      + G Y   A N +GQA  + ++ V    A                      
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP  +Q  +   VR G  V L  +VTG       + + 
Sbjct: 103  ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
              +IQ S   ++    +   L I  A  E  G Y++   N +G   +   L V  + + P
Sbjct: 141  GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200

Query: 1335 A 1335
            A
Sbjct: 201  A 201



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 1754  PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
             P   P+F + +R+L V   S A   CK+ G+P P V W++  +  I +   ++I   + G
Sbjct: 24552 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24611

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                LII+ V  DD   Y  +A N  G  + TA L VE
Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P F    R   + EG    F C+I G P PE+ WFK++  I  S +  I    +   SL 
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26820

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I +    D  KYT KA N  G+ + TA L+V  + E
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
             P PP   P  +D   SS  L W     DGGS V  Y +E  +   + W++      R T 
Sbjct: 10050 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10107

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
               V  L     YKFRVRA+N+ G  EP + +++  + ++   P  +++ S  D
Sbjct: 10108 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10160



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
             KP  P   P   D    +  L W     DGGS +  Y +E        W  +      R 
Sbjct: 11430 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11489

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
              +F V  L+  +EY+FR++A N+ G  EP + +E     +    P+ E++V+  D
Sbjct: 11490 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
             TES   + K    K  P    PP++ +  +++        E  G   +TG      +  +
Sbjct: 12010 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12067

Query: 1269  CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
               W+   K       MKV+N              +H   + +  EN++G  +  +    V
Sbjct: 12068 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12116

Query: 1329  DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
                DP  P G P      D    S+TL W    YDGG+ +  Y +E+       S ++ W
Sbjct: 12117 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176

Query: 1379  KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             K     A      F V  L  + EY+FRV A N  G   P++  E     E  E P+ ++
Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236

Query: 1436  EVS 1438
             + S
Sbjct: 12237 DAS 12239



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
             D+  S++TL+W    YDGGS +  Y +E   +  + W ++ T + T     V  L    +
Sbjct: 23273 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23332

Query: 1400  YKFRVRAINVYGTSEPSQESELTTV 1424
             Y FR+RA N  G SEP +     TV
Sbjct: 23333 YLFRIRAQNEKGVSEPRETVTAVTV 23357



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
             AP F   L++  V    +  L C V G P P + W   G+ I     +Y     + G  +
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I     +D   Y   A N  G VS +A + V                P+K   P  L+
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24660

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
             G+  +  + G  V++ +  SG P P + W   G ++ ++   H++   T+    +  VFP
Sbjct: 24661 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24716

Query: 688   -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
                  +D G Y   A N  G   +     V  V +P  G +   +S+       +  AS 
Sbjct: 24717 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24776

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKA 760
             G S + +  +         WLR G+A
Sbjct: 24777 GGSKITNYIVEKCATTAERWLRVGQA 24802



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
            PDPP        I  +++ LSW     DGGS V  Y +E   WD   +  + W++     
Sbjct: 9640 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9698

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
                 F V+DL+   EY+FRV+A+N  G S+PS      TVG    ++P+ P
Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9745



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
             + G + K    + G P P + W+++ + + +     L C +  T  L    + + DR   
Sbjct: 20513 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20568

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             G Y  +  N  G+   T+ + +        G P+  KT+         E    +W     
Sbjct: 20569 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20620

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
                 K+   +V++ +  R    +      +        +KGN  +            +P 
Sbjct: 20621 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20680

Query: 205   ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
                SV  KN        G+ +   +   +  VV     A   +++S   ++  D  +  +
Sbjct: 20681 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20740

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
              +  K T  D R++VT +              + + C+    G  P        +P    
Sbjct: 20741 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20786

Query: 321   KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
             K     D P    +  +   T SSITL  ++   +      G  V    GEE +      
Sbjct: 20787 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20846

Query: 379   PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
                  T +       PG+     VS    A +  P+E             P+        
Sbjct: 20847 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20906

Query: 422   -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
              S   K  + V+      G P P V W  +     +  GS   Y  E+  S  L  +   
Sbjct: 20907 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 20962

Query: 479   TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
             TR D+G Y  T  N  G+   S T+ V         ++L V  V+    ++L D  +I+G
Sbjct: 20963 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 21021

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
                ++   +      + TW +            +       + D   +    +  LAEN 
Sbjct: 21022 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 21072

Query: 589   LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
             +G                   E   PV  ++  API    + D               DG
Sbjct: 21073 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 21118

Query: 638   SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
               V     V      E  W H G  I ++ +    Q   Q  L  +     + G      
Sbjct: 21119 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21175

Query: 698   WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
               + G +  + ++   E      P        VT  +G +V +     G P P++ WL+D
Sbjct: 21176 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21228

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
             G  L K++      + E+  TL +K  +  H G+Y ++L N V  C   V + +      
Sbjct: 21229 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21285

Query: 818   ALPRG 822
             + P+G
Sbjct: 21286 SKPKG 21290



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)

Query: 1308  YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + +  EN  G  S       T+   P  P GTP   D+   ++TL W     DGGS +  
Sbjct: 21457 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21516

Query: 1366  YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
             YSIE     N+ W      +++ C+   + V  L P   Y+FR+ A N  GT S PSQ S
Sbjct: 21517 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572

Query: 1420  ELTTVGEKPEEP 1431
              +    ++   P
Sbjct: 21573 GIIMTRDENVPP 21584



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)

Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            +EAV  +   VKP F + ++++ + EGS      +  G P+P++VW K+   I   ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557

Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
            I  +   G  +L I      D A YT  A+N  G  T   ++ VE +E  E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)

Query: 388  GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
            G+ + +V  K  + R+ + G R     KF S  + Q VKE +T  F CE+S   K  V W
Sbjct: 5180 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5234

Query: 448  FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
            F     +     ++ +  +  +H L + +    D                        +L
Sbjct: 5235 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5284

Query: 508  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
             V+E  P F+  L D   +E  +  L+C V    VP + W  +G+ I      S    G+
Sbjct: 5285 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5342

Query: 566  AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
               L I+ A  +D G Y C      G     A VTV  +           +   KP    
Sbjct: 5343 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5384

Query: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
                L  ++V  G      +++S  P     W   G  +  S D    + G +H L +  
Sbjct: 5385 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5439

Query: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
                 TG  + +A N+    ++ A L V+E        FI+    V           C +
Sbjct: 5440 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5491

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
            + +P  T  WL+  + +  D   FE++++    ++V+K
Sbjct: 5492 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5527



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
             F+ KL    +  G+   L  + S  P   + W  +    L+  +  I +   +L    I 
Sbjct: 10452 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10507

Query: 1159  KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
             KA   D G Y  V +N  G  +  CQV V D P                   PPV     
Sbjct: 10508 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10549

Query: 1219  DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             D   K        P        I     +K   G+ V +    + +   TC   K  K +
Sbjct: 10550 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10605

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             +  +++   ++EN                Y +       S +A+    V D PD P  T 
Sbjct: 10606 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10650

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
                D    S  ++W    +DGG  + +Y +E  ++ +K W  +        T F V DLL
Sbjct: 10651 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10705

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
                +Y+FRV A N  G  +PS  S+     +   +P   V     D     VD
Sbjct: 10706 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10758



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QL  PV++K L                   PP F        V  G+  +      GRP
Sbjct: 15761 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15803

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
              P VTW K NVPL+ + RV+        +L I    ++DVG Y   + N +G+A
Sbjct: 15804 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 26/77 (33%), Positives = 44/77 (57%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V+ GQ  +    I+GRP+P +TW K  +PL+ + R++V++   +  L I   ++DD G Y
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928

Query: 232   TCLVVNGSGKASMSAEL 248
                V N  G+ + S E+
Sbjct: 16929 GITVANVVGQKTASIEI 16945



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/72 (34%), Positives = 40/72 (55%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G+  +    + GRP+P ++W+K   PL+ + RV+V E     VL I   N+DD G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010

Query: 232   TCLVVNGSGKAS 243
             T    N +G A+
Sbjct: 18011 TVTATNSAGTAT 18022



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
             P F+  + +     G   RF   I  +P+P V W+K  Q I+     + +  + D+ G  
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25376

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              L I+ V  DDDA+YT  A N  GE +C A+L V
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)

Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
            +S +  + A L  V    P +K    + I  LEV  G  A+F C+I+  P+    WFK  
Sbjct: 4444 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4499

Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
            + I ES    I   +  + SL I      D  +YTCKA N  G  +CTA L V T+  GE
Sbjct: 4500 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4557



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G   R    I GRP P+V W K +  ++ +A + V+      VL+   VN+ D G Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16639

Query: 232   TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
             T  + N SG  + SA ++++ LD+ +                                  
Sbjct: 16640 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16697

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
             V + +AT       VTN      K+D L+          A        P +   P   A 
Sbjct: 16698 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16757

Query: 312   SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
               PQPP +  ++    +  +   T       S I      +Q +         R   L  
Sbjct: 16758 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16816

Query: 364   LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
             +  +   GEE          K  + PR    P     + ++D+V +              
Sbjct: 16817 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16857

Query: 412   AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
               P  +    S  V+  Q +K    +SG PKP + W  +G P+ +Q   I V +      
Sbjct: 16858 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16914

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCS 499
             L + +    D G Y  T +N  GQ + S
Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTAS 16942



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E  A E    KP     ++D  V   S A+F  K  G P P  +W KD ++I +   +++
Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
               D+ G   L I      D   YTC   NS G  + + +L ++ +++ E +
Sbjct: 26529 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26578



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R      GRP P++TW +       + +V + +      L I   +++D G
Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17719

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
              Y   + N SG  S SA ++++ LD+         K    +VRK+   ++ +   +D   
Sbjct: 17720 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17771

Query: 290   AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
               AK KN    +R  +    AN   +  + S K+E+  +                     
Sbjct: 17772 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17830

Query: 329   ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
                      P + P    L    +TS+S+  +        R  G  V + P G E K   
Sbjct: 17831 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17889

Query: 376   PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
                         GL S        KA N +         +P+  +  +  P  +    + 
Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17949

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              ++  + +K    V G P+P ++W  +G P+ +Q   + V E A S  L + +    D G
Sbjct: 17950 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 18008

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
              Y+ TA+N+ G  + + ++ V       V P  F  V  D  VI
Sbjct: 18009 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 18052



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +++K G+  R    + GRP P+VTW K  V ++    + +++  G   L +    +D  G
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21655

Query: 230   VYTCLVVNGSGKASMSAELSIQ 251
             VYT    N SG A    ++ +Q
Sbjct: 21656 VYTVEAKNASGSAKAEIKVKVQ 21677



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P   K ++D+    G AA+  C+I G P P++ W++  + + +SR +++  D   +   +
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +++   +D+  YTC A N +GE   +++L+++
Sbjct: 24221 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24251



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             PT  +       + V  G  V + + ++G PPP   W   G++++ESE    E       
Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
             L I+E    DTG YT E  N  G    T  V+ + +P   T P  I +    S+T S   
Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23483

Query: 735   ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
                 G + L    +         WL   +++ + T  F  L   + +   +     +  G
Sbjct: 23484 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23543

Query: 791   QYEILLKNRVGECSCQVSL 809
              Y   L++ V EC   + +
Sbjct: 23544 SY---LQSEVIECRSSIRI 23559



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
            AP FI  P    + EG +  F  +V G P+P V W ++G P+T+G R+ +    + G   
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
            LVI     +D G+YT    N  G    +  L  E  +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)

Query: 1730  LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
             ++A+  +   D  Q  +  +A++   + P F        V+ G   + D    G P P V
Sbjct: 15749 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15807

Query: 1790  VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              W KD+  ++++     +  E+ N  L I D C +D   Y  K  NS GEA  T  +IV
Sbjct: 15808 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
             K   P TP     PP+    P +       SV L     K  G   +T  +++ ++   +
Sbjct: 23943 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24002

Query: 1281  S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
                 H K + +     +T L    E+   + ++ +N +G S  +  +  VV     DKP 
Sbjct: 24003 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24060

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
              P      S I   S+TL W     DGG  +  Y +E   S +  WK+      +   F 
Sbjct: 24061 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24119

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
             +  LL   EY+FRV A N  G S P     S +++LT+ GE P   K+  +V+
Sbjct: 24120 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24171



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P F+ + ++  V+        C+V+G PKP V W+ +G  +        + E  G ++  
Sbjct: 24556 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24615

Query: 474   LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
             ++ + T D  T Y   A+N  G +S + +L+VE  A + + P     +     + G+   
Sbjct: 24616 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24674

Query: 533   LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
             ++    G P P ITW   GQ +       +  V         P     +D G Y   A+N
Sbjct: 24675 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24733

Query: 588   ALG 590
               G
Sbjct: 24734 RFG 24736



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)

Query: 171   VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V +EG   ++ CKI    Q  QVTW  G   L+ S +  ++ ++G+ +L +  + + D G
Sbjct: 25206 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25265

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
              Y C VVN  G+ S  AEL ++G+      + R T
Sbjct: 25266 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25300



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)

Query: 1105  QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
             ++ H+  G  L L   +   P   + W    +   T   I ++  GS   + I  A  ED
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10911

Query: 1165  RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
              G+Y    +N AG    S +V V D P              P+      +  +S     K
Sbjct: 10912 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10959

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P                         G SV     V      +  W       ++  H 
Sbjct: 10960 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10997

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
                 +E    L  +AA            EN+ G          +   DP  P G P    
Sbjct: 10998 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11045

Query: 1342  --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
               D+  + ++L W     DGGS +  Y +E  +   + W +  T  +    V  L     
Sbjct: 11046 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11105

Query: 1400  YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             Y+FRV+A N+ G   P     +    EK   P  E++V
Sbjct: 11106 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11142



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L IK G + + +  V+G P P+VTW ++G  I       +   + G+ SL +     + R
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21654

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
             G YT EA N SG+ +  +++ V+ +  K +G    +   G++ +
Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)

Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
           ++A P F  + QS  V++   V+ +  V+GIP P V ++ +G  + +     ++ ++   
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158

Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
           + L + +A   DSGTYS  A+N+ G+ + +  L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
             W K  K +  + H KV     G               + +  EN  G          +  
Sbjct: 20344 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20392

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
             +D  +PP      +DI  +S++LSW   ++DGGS +  Y +E  D  +  W +       
Sbjct: 20393 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20451

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
              T F +  L  + +Y+FRV A N  G+ S PS+
Sbjct: 20452 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20484



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
            +  P PP   P  +D  S+++ L W   +++GG  +  Y ++        W        +
Sbjct: 8628 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8685

Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               + V+++    +YK RV A+N  G   P  E++  TV E  E P  E++VS
Sbjct: 8686 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8737



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)

Query: 1125  PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
             PP T+ W  + K L +     +    S   ++I +    D G Y    +N  G+ + S  
Sbjct: 20927 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20986

Query: 1184  QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
              V V D PA+      +  SR   + L  PP++   S   +  ++K+ A K         
Sbjct: 20987 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21038

Query: 1239  QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
                                            TW     +   +    ++ SE        
Sbjct: 21039 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21064

Query: 1299  AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
                      + +L EN++G  +       V   + PA     S  D   +S+ LSW    
Sbjct: 21065 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21115

Query: 1357  YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             +DGGS +  Y +E      +TW      ++    V  L      +FRV A N  G S+P 
Sbjct: 21116 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21175

Query: 1417  QESELTTVGEKPEEPKDEVEVSD 1439
                 + TV E    P  EV++SD
Sbjct: 21176 TIGPI-TVKELIITP--EVDLSD 21195



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
             SE   K+T L    E+   + ++ EN  G   A     L    +P  P G P     +D 
Sbjct: 21836 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21893

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
               ++++L W    +DGG  +  Y IE+  +    W ++    C  T + V DL    EYK
Sbjct: 21894 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21953

Query: 1402  FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             FRV AIN  G  +  + +      ++   P+ +++ +
Sbjct: 21954 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21990



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 718   GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
             G  P    + + VT  LG++  +SC I G P P + W R GK L + +  +++  +    
Sbjct: 24158 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24216

Query: 778   TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             TL +   +    G Y  +  N VGE      L+LQ
Sbjct: 24217 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)

Query: 145  SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
            S P  E +     E P  F     L  + VK G        +TG+P+P++TW K ++ L+
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7360

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
               R+++        + I    + D G Y    VN  G+A+   E+++            
Sbjct: 7361 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7420

Query: 253  LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
             D  N S +        D   ++TN + +    DS
Sbjct: 7421 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7455



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
            P PP G P        S+ +SW     +GGS +  Y +E  +  +  W  ++        
Sbjct: 9227 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9285

Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
             +   FNV  LL   +Y+FR  AIN  G   PS+ S+    G+   P  P    EV D
Sbjct: 9286 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9343



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L   V   PP  I W+     L+    + +        +  E     D G Y   
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13395

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G+ E +  V V D P                   PPV  T  + +         P
Sbjct: 13396 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13437

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P       II +   ++       +   K   T    C+   FR          V N E 
Sbjct: 13438 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13480

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
             G               + +  EN+ G          V     P G      +RS   SS 
Sbjct: 13481 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13528

Query: 1349  TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
             ++ W     DGGS +  Y ++     NK W+ +    S  ++ +DL    EY FRV A N
Sbjct: 13529 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13587

Query: 1409  VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
               G   P   SE+T V       +D+V   D D K
Sbjct: 13588 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13613



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             S +  +GQ + I   I+G P PT+ W +DG  L K T    V  + D+ TL +K+     
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16924

Query: 789   AGQYEILLKNRVGECSCQVSLM 810
              GQY I + N VG+ +  + ++
Sbjct: 16925 GGQYGITVANVVGQKTASIEIV 16946



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             VV++     R    I GRP+P+V W K    L   A++ V+  +   +L I  V + D G
Sbjct: 18745 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18802

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
              Y   + N SG  S +A ++++ LDS +      +RE K  +          D   ++TN
Sbjct: 18803 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18860

Query: 278   VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
              I ++ +      A  + NC+         Q G S  +   +  +       E+ +    
Sbjct: 18861 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18920

Query: 331   TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
             + P  P  + T   +T   A ++ E        +  G  V   +    K     +  T  
Sbjct: 18921 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18980

Query: 384   TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
                 GL  G + V   AA         R    P      E KP  +       VK  + +
Sbjct: 18981 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 19040

Query: 432   KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
             K      G P+  V W  +G  + ++   + V        L + +A   D GTY    SN
Sbjct: 19041 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 19099

Query: 492   AQGQLSCSWTLQV 504
             + G ++   T+ V
Sbjct: 19100 SAGSITVPITIIV 19112



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 40/81 (49%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + VK G        + G+P P V+W K    L+P+  + ++ +  +  LE+  VN+ D G
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12992

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              YT    N SG  S + +L +
Sbjct: 12993 DYTITAENSSGSKSATIKLKV 13013



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)

Query: 1131  WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
             W+  GK ++ +    ++   +   ++I+ A  +D G Y   A N  G      +VTV D 
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100

Query: 1191  PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
             P                   PP     S+ + +K     TPP       I  +  +++  
Sbjct: 14101 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14140

Query: 1251  AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
               E+  L             W    + IQ   H+  +  + G++     +   H G    
Sbjct: 14141 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14181

Query: 1311  LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
                   G       + +VD+  P  P   P  S++  ++ T+SW     DGGS +  Y +
Sbjct: 14182 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14236

Query: 1369  EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
             E  +  +  W        +     V  L     Y+FRV A N  G   PS+ S+   + +
Sbjct: 14237 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14296

Query: 1427  K--PEEPKDEVEVSDDDEK 1443
                P  P     V+D  +K
Sbjct: 14297 AAYPPGPPSNPHVTDTTKK 14315



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)

Query: 12    ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
             I++T++++ P    S P+T   A  +PPR          L +K G     +  V G P P
Sbjct: 12895 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12953

Query: 63    QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              V+W ++G  +    G +  +    R   +L + +V+ +D G YT  A N SG++  T++
Sbjct: 12954 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13010

Query: 121   LTV 123
             L V
Sbjct: 13011 LKV 13013



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 1325  LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
             +  +D   PP     P  +D   +S++L+W     +GGS V  Y IE+       W +  
Sbjct: 23652 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23709

Query: 1383  TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
              C +T   +++    H     EY+FRV A N  G  EP++      V E  E P  E++
Sbjct: 23710 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23767



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
             + + PS        ++  G+D  ++  V G P P I+W+ +G+P+ Q  R   E  A   
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995

Query: 567   ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
              LHI++   +D G YT  A N+ G  + +  V V EK
Sbjct: 17996 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 18032



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QLG PV+++          +E +PS+  E P  F T      VK  +  +      GRP
Sbjct: 19008 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19050

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             Q  V W K    L+ + RV+VS    +  L I   +++DVG Y   V N +G  S++  +
Sbjct: 19051 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19108

Query: 249   SIQGLD 254
             +I  LD
Sbjct: 19109 TIIVLD 19114



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)

Query: 106   CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
             C  TN         ELT +  +  +    V ++   D  S P+  T P I  +   PP+ 
Sbjct: 19362 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19417

Query: 164   ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
                +     +VVK G++ + +  I GRP P ++W K  + ++  AR  +   +   +L +
Sbjct: 19418 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19477

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + D G Y   + N +G  S++    +
Sbjct: 19478 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)

Query: 1700  AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
             AV +  + S M   S +   KS        L++ +  +  ++  A LE  + E+      
Sbjct: 26123 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26182

Query: 1760  FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
                T+        R + V EG +ARF C  +G P P V W +  Q +  S   Q+   + 
Sbjct: 26183 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26241

Query: 1812  GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                +  IS V   D+  Y+    NS G+      L ++
Sbjct: 26242 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
            +++   KP+F K +  L +     A F+C++    DP +V  W  D + +  +   ++  
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +E G CSL        D    TC+A N  G    +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)

Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
            G  P+T  ++  ++++      KV +     + T+    Q     + +   NK G  +  
Sbjct: 7143 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201

Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
                 VN+ T    PDPP       D  ++S+ L+W     DGGS ++ Y +E     + 
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7260

Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             W         T   V  L     Y +RV+A+N  G S+PS+ +E     +  E P+  +
Sbjct: 7261 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7320

Query: 1436 EV 1437
            +V
Sbjct: 7321 DV 7322



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
            K    ++    + G P P+ +W  +G   +  ++G  ++ EDA       S  + + + +
Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
               +G YS TA N  GQ + +  ++V       + L V ++      +       +G D 
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9569

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
                 ++G  + + T  ++G+        C  G     + D L E    +   AEN  G 
Sbjct: 9570 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9620

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                  V   ++ ++R      P+ P  P           +K+  G     TV +S  PP
Sbjct: 9621 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9663

Query: 652  PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
                           + W   G + +     + ++   +    ++++       +  +A 
Sbjct: 9664 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9722

Query: 699  NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
            N+AG  +  A +   +      P  I     +    G +V I   I G PFPT+ W +  
Sbjct: 9723 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9782

Query: 757  ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
                D K       H   L  +D  TLV+ + +    G Y I   N +G  S ++ L
Sbjct: 9783 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9839



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)

Query: 575   PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
             P D   +  +A NA+G +S            S+ S  ++     V P     P +  GL 
Sbjct: 21548 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21597

Query: 631   DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
                +  G  + +   V G P P V W  +G EI++  +          SL +++   +  
Sbjct: 21598 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21654

Query: 691   GTYTCEAWNSAGEVRTQAVLTVQE 714
             G YT EA N++G  + +  + VQ+
Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQD 21678



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
            +++P PP     +SD   SS+ L W     DGGS +  Y IE  +     W    +    
Sbjct: 6917 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6975

Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
              ++ V  L   ++Y +RV A N  G S+PS+     T  +   EP  ++    D
Sbjct: 6976 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7030



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)

Query: 574   LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
             +P++  T T L E A  Q    A   V+    S  S+ +  +A +  P   + +   S L
Sbjct: 12874 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12933

Query: 633   KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
              V  G+ V +   V G P P V W  +G  ++ +E     +   Q +LC  E+F    +D
Sbjct: 12934 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12990

Query: 690   TGTYTCEAWNSAG 702
             +G YT  A NS+G
Sbjct: 12991 SGDYTITAENSSG 13003



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 25/82 (30%), Positives = 36/82 (43%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             + KE    R    I G+P P V+W KG  PL    RVSV        L ++   + D G 
Sbjct: 13621 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13680

Query: 231   YTCLVVNGSGKASMSAELSIQG 252
             YT  + N +G    +  + + G
Sbjct: 13681 YTITLKNVAGTKEGTISIKVVG 13702



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             LT  P+  LP     I+ G   K E  V G P P ++W ++G+P+    R  ++     T
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995

Query: 89    FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               L I   +++D GKYT  ATN +G     + + V
Sbjct: 17996 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
             NA    S    S   +    E  P +  +  +    L +  G + R    ++G P P V 
Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21619

Query: 1791  WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             WFKD   I +  + +I  D  G+ SL + D   D    YT +A N+ G A    ++ V+
Sbjct: 21620 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
             I+ G+    +  V G PEP++ W +  + +    +  L   G R T   VI      D G
Sbjct: 22687 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22744

Query: 103   KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
             KYT    N SG + V+V + V  S     G+  VS+   ++    +S P  +    I   
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22803

Query: 159   CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
                +  T     V+ EG+    S  +T   +      +V  +    P  P     +  +N
Sbjct: 22804 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22863

Query: 214   GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
                +    G+ ++   G    ++     ++    E+S   +D   +  +R T+       
Sbjct: 22864 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22923

Query: 270   -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
              D R +VT+++               + C    R  +   A NS+P     S   SC++ 
Sbjct: 22924 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22966

Query: 328   ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
                  P +AP+  V+  T  SI+L   +   +     +G +    E+           A 
Sbjct: 22967 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23024

Query: 377   PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
              R   F      +G +     AA   + ++G  + +    E +P                
Sbjct: 23025 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 23081

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
             ++  ++   +++    VSG P P + W  +G  +     S  + +   S+ L ++ K   
Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23137

Query: 480   RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
              D+G Y+  A N  G+ S +  ++V         + V EV+    ++  +   I+G    
Sbjct: 23138 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23193

Query: 533   LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
                   G PV   I          +   T +       I   +      +  L EN  G 
Sbjct: 23194 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23247

Query: 591   --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
                   S  V V E          +P+ P+K            L+V+D ++ T+T  ++ 
Sbjct: 23248 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23283

Query: 649   NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
               P     L++G            + GT+  + +  + P   E T T   E       +R
Sbjct: 23284 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23338

Query: 706   TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
              Q    V EP +      +   R             ++    G+ V +   IAG P P  
Sbjct: 23339 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23398

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              W   G  L +++    V  +  V  L +++      G+Y + LKN  G  S  + +++ 
Sbjct: 23399 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23457

Query: 813   NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
             +               A ++    EP   +    GG    G   ++  + RPGW
Sbjct: 23458 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23507



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
             P PP G P         + + W     DGG+ + +Y ++  +  +  W  +        T
Sbjct: 22868 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22926

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                V  L+   +Y+FRV A+N  G SEPS+ S   +  E    P
Sbjct: 22927 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22970



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
             V +   S  S++   ++P     +P  E    +   + + I+ GA+ +    V G P P 
Sbjct: 23048 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23105

Query: 64    VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             +TW + G  + S  R ++D        L++  V+  D GKYT EA N SG +  TV + V
Sbjct: 23106 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23162



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)

Query: 988  KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045
            ++++ + +GS   E +    VES   +S  + S       V         K + +A  ++
Sbjct: 4266 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325

Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105
              K   + KP E  + +S E   ++V   V  +    G    +         P     L 
Sbjct: 4326 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4375

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164
            D    EG  + L   +++     + W    K + + +     Q+ +  ++ I+K   ED 
Sbjct: 4376 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4433

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
            +G Y C A ND+G+   S ++TV                                    K
Sbjct: 4434 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4458

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
            + AP    K           E  +V  G   +   ++     +   W K  ++I ES+  
Sbjct: 4459 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4508

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             + +S+  S L IL  +   CG YT    N+ GS      LTV
Sbjct: 4509 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)

Query: 752  VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810
            V+W  + K +  D   F+ LQ+++ +TLV+ KV    H G+Y     N  G+ +    L 
Sbjct: 4397 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4455

Query: 811  LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870
            +   +A  + R  EP    ++  G +           ++R  W   G+  + E D   +R
Sbjct: 4456 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4511

Query: 871  G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917
                     +L+ +V +  ++T +A  +         L      G+K   K L E   K 
Sbjct: 4512 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4569

Query: 918  IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963
             P E++  ++ L++   + +PK   ++  KV  P           ++V+  +V  ++   
Sbjct: 4570 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4627

Query: 964  KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023
            K P P KVP  KPA P           LPA       E   A+      P    +P+   
Sbjct: 4628 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4673

Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083
             PV    P    K    A   E  KP G   P + +   +   ++ + +       G   
Sbjct: 4674 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4728

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137
              +     + +     F ++++D+ + E    G   + +C VS   P+T I  W  +G  
Sbjct: 4729 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4785

Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
            ++ +   +FI   ++  L  + ++ +   D G Y CV +    +   + ++ V++ P
Sbjct: 4786 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4839



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)

Query: 1111  EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
             EG  +   C++ + D    + W    + L+ ++   ++ E  +  + ++     D G Y+
Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25268

Query: 1170  CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
             C   ND G+     ++ V         +  +   RR               T+KK K   
Sbjct: 25269 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25308

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
              T      PP+      ++    GE+V     +T       TW K  ++I+  ++ K   
Sbjct: 25309 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25368

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
              E+ +   +LTI +   +    YT++  NK G    +  LTV   P P            
Sbjct: 25369 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25428

Query: 1335  -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
                     G     +IR S +   TL W     DG       +IEI       +      
Sbjct: 25429 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25479

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
                + +++D LP+    +RV A N  G++      ++  +  K +E K + E     +K+
Sbjct: 25480 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25536

Query: 1445  PEVDYRTVTI 1454
              +   R   I
Sbjct: 25537 IDKTLRMAEI 25546



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+   + +   +G  A FE  V G P P VTW +  + + +   + +     G+ + +
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
            ++    ED G Y C+A N  G      EL V          P  +K+  +          
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3819

Query: 145  SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
              PAVE   S       + AT +   ++K   +   + +++     +   L   +PL   
Sbjct: 3820 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3874

Query: 205  ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
               S+ E++ +          +    + C  +NGS         S  L +Q + S  ++F
Sbjct: 3875 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3923

Query: 261  VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
             +         ET+A  SD  K   + +S E +++SL         + P+ G  P     
Sbjct: 3924 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3977

Query: 312  SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
            S  +PP  S L S  +    +P+   +  T+    +TLQ    Q
Sbjct: 3978 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4020



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)

Query: 388   GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
             GLG  D         IP+E Q     P  E   +  E   VK   TV+F   + G+P P 
Sbjct: 11117 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11169

Query: 445   VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
               W  +G+ ++  E    V  D  S  L +     RD+G Y  T SNA G  + +  L V
Sbjct: 11170 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             LP      KE +  + +  ++G P P V+W +   P+ +  R  ++     T +L+++  
Sbjct: 13615 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13673

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTVEG 125
              + D GKYT    N +G ++ T+ + V G
Sbjct: 13674 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13702



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)

Query: 1717  SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
             S ++  +  P+ P      E++    E V    + A  +    +K   SK I  L  VVE
Sbjct: 26309 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26368

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
              S  R           EV W+KD + ++E+ HFQ  Y  DG   L I+++   D  +Y C
Sbjct: 26369 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26419

Query: 1832  K 1832
             +
Sbjct: 26420 E 26420



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L+DV+V EG K +L+C+VS     ++ W LN + +K    +    +G+   + I +    
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
            D G YK +     G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            PHV+  F + + DL+V E   ARF+C++    + +V WFKD   I++ + + I   +   
Sbjct: 6000 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6055

Query: 1814 CSLIISDVCGDDDAKYTCK 1832
              L+I+    DD+A+Y+C+
Sbjct: 6056 RILVINKCLLDDEAEYSCE 6074



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
             ++E  P +   L    +  G+   ++  V+G PVPR+TW  +G  I+   +   T   G 
Sbjct: 21585 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21641

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
               L ++DA  +  G YT  A+NA G       V V +
Sbjct: 21642 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21678



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            E  H++  F K I+D++V+E   A F+C++   PD  V W KDDQ ++ +   +I  ++ 
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +  L+I      D  KYT  A    G    TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)

Query: 115  RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
            RQ TV+   EG+  K     V +   G     P  ET+P    E     A +L     G 
Sbjct: 8687 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8741

Query: 170  VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
            + +  G+  R    +TGRP P   W K    L    RV +        L I    + D G
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8800

Query: 230  VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
             Y     N  G    +A           L ++ + +  +  +        D   E+T  I
Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8860

Query: 280  --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
               K++K+ +    +E      + +    G    +   ++ +    PP E       D  
Sbjct: 8861 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8920

Query: 328  SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
             P T+P+     ++T S+ITL       EPR+ G   +     E++R   P         
Sbjct: 8921 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8976

Query: 382  FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
             PT    + + D         KA N        +P+    Q D   P    +   +  + 
Sbjct: 8977 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 9036

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
            +VK  + V    +V+G+P P++ W    T + +   ++++ ++  S       L + KA 
Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096

Query: 479  TRDSGTYSCTASNAQGQL 496
              D GTY+ TASN  G +
Sbjct: 9097 REDKGTYTVTASNRLGSV 9114



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)

Query: 511   EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
             +V P+FSS     +V  GQD  ++  + G P P ITW  +G P++       T    +  
Sbjct: 16859 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16914

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I++   +D G Y     N +GQ + S  +   +K             P  P  P+   
Sbjct: 16915 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 16961

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPP 651
              +S            ++ +S NPP
Sbjct: 16962 DVS----------AESITLSWNPP 16975



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             +  G  + + + V G P P + W+ +G  ++++   + E+  T   L I+E   +D G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010

Query: 694   TCEAWNSAG-EVRTQAVLTVQEP 715
             T  A NSAG      +V+ +++P
Sbjct: 18011 TVTATNSAGTATENLSVIVLEKP 18033



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +K G   + E  V G P P + W ++G+ +    +  +      T +LV       D G 
Sbjct: 15101 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15159

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
             YT  ATN              G FAK +    V    G      +   V +   +    P
Sbjct: 15160 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15206

Query: 161   P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
             P      K+   +V++ +  R +       + QVT LK    L+ +    RV    K G+
Sbjct: 15207 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15265

Query: 216   -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
                     VL ++     D              +  C     S   S      ++  D A
Sbjct: 15266 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15325

Query: 257   NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
              + +++  K T +D+R +V+ +    E +   +   A   +  SP            +P 
Sbjct: 15326 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15385

Query: 316   PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
             PP   + L++ + S   A   P+    S           PE        P A GL   S 
Sbjct: 15386 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15444

Query: 367   SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
             +          +   +     GLG   +V    KA +R +P E + D+   K  +     
Sbjct: 15445 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15499

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
              ++   T++    + G P PEV W  +       E   +   ++ S Y  L+       D
Sbjct: 15500 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15553

Query: 482   SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
             SG Y  T  N+ G  S    ++V       + L V EV  +  ++  D  +++G   +  
Sbjct: 15554 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15613

Query: 535   CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
               V      R       +      + C     ++   D L E    Y   LAEN  G + 
Sbjct: 15614 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15662

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               A      K S R      P+ P K T            +MD ++   +V +S   P  
Sbjct: 15663 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15701

Query: 654   VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                 H+G           + +G+ + + C      E T T   +    +  V  Q    +
Sbjct: 15702 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15757

Query: 713   QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              +P   + P  I+K             + T   G+ + +     G P P V W +D   L
Sbjct: 15758 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15816

Query: 762   CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
              K T        E+   L +K       G Y + L N  GE
Sbjct: 15817 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15856



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)

Query: 1228  PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
             P  PP A   P++     +   +R  E         G   I   W+  K R  I   +  
Sbjct: 22465 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22519

Query: 1285  KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             KV   E   K+T L    E+    Y L       + +A   +   +  D P G P  +D+
Sbjct: 22520 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22578

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
               S+++L W   +YDGGS V  Y IE   + +  +  W +          F V  L    
Sbjct: 22579 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22638

Query: 1399  EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
              Y+FRV A N  G  S+ S+ +   T  ++   PK E++
Sbjct: 22639 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22677



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)

Query: 656  WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            W+ +G+ I+ES    F   G    L I +V   D G YTC       E  + A L V+E 
Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838

Query: 716  HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
                  +  +    VT   GQ + +SC +  +    V W +DGK + +  G         
Sbjct: 4839 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4893

Query: 776  VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
            +  L +       AG Y + ++N    ECS  V ++
Sbjct: 4894 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4929



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
             P  P G P   D+  S+++L W    +DGGS +  Y +E        W    T       
Sbjct: 12817 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12876

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               +    L    +Y+FR  A      S PS+ S+  T+  +   P+ ++ V+
Sbjct: 12877 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12928



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
             L +K G T +F   +RG P P   W  +G  I +   + ++      FS  L I      
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11204

Query: 100   DRGKYTCEATNGSGARQVTVELTV 123
             D G+Y    +N +G++ V V LTV
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTV 11228



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 601   HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
             +EK  S   +  +PV A      P F    +   V+ G  + + V   G P P V W  +
Sbjct: 15753 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15812

Query: 660   GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
                ++++   + E       L I++   ED G Y  +  NSAGE + T  V+ + +P   
Sbjct: 15813 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15872

Query: 719   TQP 721
             T P
Sbjct: 15873 TGP 15875



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V+V+ G   R    + GRP P+VTW K  +      +  V   + M  L I    +DD G
Sbjct: 12244 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12302

Query: 230   VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
              Y+  +VN +G+ ++   + +      +     S V +T          +D   +VT+ I
Sbjct: 12303 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12362

Query: 280   SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
              ++ + D                                A        P     P  A++
Sbjct: 12363 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12422

Query: 312   --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
               S+P PPR+ ++     +  T    P L+    K    IT      QP  R     V+ 
Sbjct: 12423 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12482

Query: 366   ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
                        G++ K     R A   + P    G      V +A  + +P         
Sbjct: 12483 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12527

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             PK    P+   +K  + ++    V G P P   W  +G         + V++   S  L 
Sbjct: 12528 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12585

Query: 474   LLKARTRDSGTYSCTASNAQG 494
             +     +DSG YS TA N+ G
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 160   PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             PPK      ++ +K G+  R    + G+P P   W KG   +  S+ ++V + +   +L 
Sbjct: 12527 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12585

Query: 220   IHGVNQDDVGVYTCLVVNGSG 240
             I  V + D G Y+    N SG
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)

Query: 4    VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            VK V ++ +SK S +V P    R D  P  +   F+       ++EG       +++G P
Sbjct: 9719 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9772

Query: 61   EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
             P +TW +       N +P+   T   + ++D     T +LVI      D G YT  A N
Sbjct: 9773 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9828

Query: 111  GSGARQVTVELTVEG 125
              G     + L V G
Sbjct: 9829 NLGTASKEMRLNVLG 9843



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)

Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            + +KT++++EV E   A F+C++  +  P  +W K+   I  S  F+I      +  LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
             +   +D A+YT    N    AT T   I+ T    +   EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
            +EV EG+      KI+G P P + WFK      +++   + YD        D  C+L+I 
Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9812

Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
                 D   YT  AVN+LG A+
Sbjct: 9813 QSRRSDTGLYTITAVNNLGTAS 9834



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V+ GQ  R   ++ GRP+P +TW K    L    RV + +      L+I    + D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
              Y     N SG A  SA +++  LD       +  K TN  V KE    IS E+ LD+
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11656



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E V E K  + P        + +  G   R +  + G P P   W K +  +  S H  +
Sbjct: 12516 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12575

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              +  D +  LII DV   D   Y+  A NS G  T   +++V
Sbjct: 12576 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
             NA  + SE   S   + A  E  P    + P +  TI    V  G + + D  I G P P
Sbjct: 16145 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16201

Query: 1788  EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
              + W K DQ +  +   +I    D   SL + D    D   Y  KA N  GE + T  + 
Sbjct: 16202 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16260

Query: 1848  V 1848
             V
Sbjct: 16261 V 16261



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
             P PP      S +   S+TL W     DGGS +  Y IE  +  +  W  +         
Sbjct: 19611 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19669

Query: 1391  VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             V+   L    EY++RV A N  G S PS+ S L
Sbjct: 19670 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19702



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)

Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
            +G    F ++LQD+ V E     L+C VS   P  I   W  N   LK+  K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               +++++    ED+G Y  V                                       
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
              + G ++   +K KP P           I+Q   DQKV  G+ V+L  KV+  + +   
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
            WMK  +++Q S+ + +   +    L I    +E  G Y+  +     S   +V++  VD 
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401

Query: 1331 PDP 1333
              P
Sbjct: 2402 ITP 2404



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)

Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
            F K I+D+ + E    GS+A F+C +   P   +  W KD  +IRES +H  I   +D  
Sbjct: 4745 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +I  DV   D  +YTC       E T TA+L+VE +
Sbjct: 4803 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)

Query: 117   VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
             +  + TV G    Q  +  V++K      S P+  T P    +          PKF    
Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17262

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
               +VV  G+  R    + G+P P + WL+G+  ++ SAR  +   +   +L +    + D
Sbjct: 17263 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17320

Query: 228   VGVYTCLVVNGSGKASMSAELSI 250
              G Y     N +G  S    + +
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKV 17343



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
            +KS  K +++ K + + +N +  H G   +      + T+ A          F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021

Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
             V E K+ + +C+VS +P  T+ W  + + L+ T  I + +E  +  + I      D G 
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080

Query: 1168 YKCVAKNDAGQAE 1180
            Y  VA  +   A+
Sbjct: 3081 YTVVAGGNVSTAK 3093



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             +K G   R S  I G P P+VTW K +      AR+ V+       LEI     +D G+Y
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10915

Query: 232   TCLVVNGSGKASMSAELSI 250
             +  V N +G  ++S ++ +
Sbjct: 10916 SLTVENPAGSKTVSVKVLV 10934



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 21/72 (29%), Positives = 34/72 (47%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++++ G   R    + GRP P++TW K NV L+    + +   +    L    VN+ D G
Sbjct: 13331 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13390

Query: 230   VYTCLVVNGSGK 241
              Y   + N  GK
Sbjct: 13391 KYILTLENSCGK 13402



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + + + V G P P V W      +++++  +FE   T   L I E    D+G Y   
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767

Query: 697   AWNSAGEVRTQAVLTVQ 713
             A N  GEV    V+T+Q
Sbjct: 14768 ARNIVGEVGD--VITIQ 14782



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
             KD  V+  G+ F +   + G P+P I W+   Q +   AR   ++      L ++DA+  
Sbjct: 16178 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16237

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
             D G Y   A+N  G+ S    VTV+ K   R         P  P  P+ + G++  K   
Sbjct: 16238 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16284

Query: 634   -----VMDGSQVTMTVQVSGNPPPEVIW 656
                  + DG    +   V       ++W
Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVW 16312



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 1753  KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
             +P VKP FS       V  G   + +  I G P P + W KD   ++++    +  D   
Sbjct: 16857 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16911

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
               +L I +   DD  +Y     N +G+ T + E++
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16946



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 736   QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
             + + I     G P  TV+W +DG+ L K+T    V  ++ V +L +K+      G YE+ 
Sbjct: 19038 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19096

Query: 796   LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
             + N  G  +  +++++ +      P   +  SC+ +
Sbjct: 19097 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19132



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
            F + L+D  V EG   +L+C+VS +  A + W  NG + LK+ K+ I++ +G +  + I 
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5972

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
               PED   Y C    DA   + SC + V
Sbjct: 5973 DCTPEDIKTYTC----DAKDFKTSCNLNV 5997



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            L E   F     N+ + E  T K    V   P  +V W++  + I   GR+ +    R  
Sbjct: 6087 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6145

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              LVI   H ED G Y C   +     +V V                             
Sbjct: 6146 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6176

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
                     E   +F +K   + + EG+   F C I+    P V W + +  L+   +  
Sbjct: 6177 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6226

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            V      +VL +      D+G Y  +V    G A  +A L++
Sbjct: 6227 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6264



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)

Query: 528  GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
            G+   +   V G P+P+I W  N   I+      +             EL I  A+ ED 
Sbjct: 9041 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 9100

Query: 579  GTYTCLAENALGQVSCSAWVTVHEKKS 605
            GTYT  A N LG V  +  V V+++ S
Sbjct: 9101 GTYTVTASNRLGSVFRNVHVEVYDRPS 9127



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/93 (27%), Positives = 39/93 (41%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P+  + ++ +  L V  G+ V     + G P P   W  +G+EI+  E +  E       
Sbjct: 11136 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11195

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
             L I+     DTG Y     N+AG       LTV
Sbjct: 11196 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)

Query: 437   VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
             V G P P+V W   G     ++G +++ +     +L +  +   DSG YS T  N  G+ 
Sbjct: 12258 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12315

Query: 497   SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             +    ++V         L V +V  +   V       +G   V    V      R TW  
Sbjct: 12316 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12373

Query: 550   NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
                    +  T E      H+ + +P +   +   A N  G       V     K    S
Sbjct: 12374 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12421

Query: 610   EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
             + L     S+P  P         + ++ +++T         PP    L +G    +    
Sbjct: 12422 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12463

Query: 667   ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
                E+     R T++S+ ++++    TG        +   A N+ G    +    V E  
Sbjct: 12464 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12522

Query: 717   DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
             +   P  I  P  +T   G+ + I   + G P PT  W + G+     + H  V + +  
Sbjct: 12523 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12581

Query: 777   FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
               L++K V    +G Y +  +N  G  + ++ +++ ++     P
Sbjct: 12582 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12625



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T   G +V +   + G P PTV W +DG  L K     ++    ++ TL L  V    +
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12991

Query: 790   GQYEILLKNRVGECSCQVSL 809
             G Y I  +N  G  S  + L
Sbjct: 12992 GDYTITAENSSGSKSATIKL 13011



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             VV+ G   R      GRP P   W K +  L  S R  +   +    L +   N++D G 
Sbjct: 21996 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22053

Query: 231   YTCLVVNGSGKASMSAELSI 250
             YT  V N SG  S++  + +
Sbjct: 22054 YTLTVENNSGSKSITFTVKV 22073



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
             +  LA+NA G +S  +  T      + + EY    AP K      L G  DL  +  GS 
Sbjct: 22642 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22692

Query: 640   VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             + +   V G P P++IW     E+   E    +  G + +  I+     D+G YT    N
Sbjct: 22693 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22752

Query: 700   SAGEVRTQAVLTVQEPHDGTQP 721
             ++G   T+AV  + +  D   P
Sbjct: 22753 ASG---TKAVSVMVKVLDSPGP 22771



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             T  D ++ P  E    + G+           V ++ G        + G+P+P++ W KG+
Sbjct: 22664 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22713

Query: 199   VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
               L    +VS+          I   ++ D G YT  V N SG  ++S  + +  LDS
Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22768



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
            +N+ + E  TA FE  V  +  P + W +NG  I    +F +   ++G    L+I     
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899

Query: 99   EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
            ED  +YT    N   +  +TV                      E+TV  EG   K L   
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959

Query: 135  VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
            V  K+                      GD     F A    +  +++ E    +F   + 
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019

Query: 169  RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             + V E +   F C+++  P   V W+K +  LQ + R+ + ++  +  L I      D 
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078

Query: 229  GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            G YT +    +G    +A+L ++G D   RS  +E +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V + Q +   CE++   + +V W  +G  V  + G I          L +  A   D+GT
Sbjct: 4852 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4909

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+ T  NA   L CS  ++V    V  +       ++D  V      +  C +     P 
Sbjct: 4910 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 4963

Query: 545  ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
            I W      +  +P        +     L I++A+PED   Y    E         A +T
Sbjct: 4964 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 5019

Query: 600  VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
            + E    R+ E L P+               D+ + +    +   ++S    P   W   
Sbjct: 5020 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 5060

Query: 660  GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
            G  ++ S     +  G +  L + +V  +  G    +A N+     T A+LTV+E     
Sbjct: 5061 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 5112

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
            +  F    + VT    +     C +  +    V W + G  + K +  F+++ +     L
Sbjct: 5113 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5169

Query: 780  VLKKVQPWHAGQY 792
            V+   Q    G Y
Sbjct: 5170 VINDSQFDDEGVY 5182



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F+K + ++EV E    +  C++   P  EV+W+K D+ I E+  ++I   E     L+I 
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6150

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
            +   +D   Y C+  +S  +      EL  E + + +     EGE+ E
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)

Query: 8     ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
             A+  ISK S S  P  + +    E P   + P+    + +  G T + E  V G P P +
Sbjct: 17228 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17285

Query: 65    TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              W R  + I    R    C I+ T     L++      D G+Y   A+N +G++   V +
Sbjct: 17286 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17341

Query: 122   TV 123
              V
Sbjct: 17342 KV 17343



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++VK G     +    GRP P V W K +  L+  A V  ++      L I   N++D G
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19881

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
              YT  + N    AS++  L ++ LD+        T  T  DV KE
Sbjct: 19882 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19920



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +K  ++++ +  V G P P V WF +G  + ++  ++E+ +  GS  L +  A     G 
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21656

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
             Y+  A NA G       ++V+      V P
Sbjct: 21657 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21686



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
             + P       D+ + EG      C   G P PEV W    + I  +E   F I+ + D  
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27013

Query: 1814  CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +LII DV   D   YT    N  G  + T  + + ++
Sbjct: 27014 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 24/96 (25%), Positives = 43/96 (44%)

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
            +C P    +   ++V EG+           P P V+W K    ++ S R+++   +    
Sbjct: 8012 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8071

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
            LE+    + D G+YT  + N  G A+ S  + + GL
Sbjct: 8072 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8107



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
            P+      D  VIEG+   +    R  PVP ++W  +G+ ++ + R T +     A L +
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8074

Query: 571  QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              ++  D G YT   EN LG  + S  V V
Sbjct: 8075 PKSVRADAGIYTITLENKLGSATASINVKV 8104



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)

Query: 395  VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
            VSK +    P + QR    P  + K +  EV+E   V    ++ G+P P + WF    P 
Sbjct: 9727 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9783

Query: 455  RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
            ++ +    V  D   + L     C L   ++R  D+G Y+ TA N  G  S    L V  
Sbjct: 9784 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9843

Query: 507  LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
                 V P  F SV  D   +       +G   +    +      R TW+ ++ +P    
Sbjct: 9844 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9899

Query: 558  RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
               C   + +L     L      +  +A+N  G         +  +  + ++ + +P AP
Sbjct: 9900 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 9948

Query: 618  SKPT 621
             KPT
Sbjct: 9949 DKPT 9952



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)

Query: 1762  KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
             K I  L V  G+  RF   I G P P   W  D   I+   H+ ++ D   +  L I + 
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11201

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIV 1848
                D  +Y     N+ G  T    L V
Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTV 11228



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 23/80 (28%), Positives = 36/80 (45%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G++ ++   I G P P V W +DGK L +     E+       TLV+K       
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404

Query: 790   GQYEILLKNRVGECSCQVSL 809
             GQY + L N  G  S  +++
Sbjct: 18405 GQYILKLSNVGGTKSIPITV 18424



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 26/85 (30%), Positives = 34/85 (40%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L+L   V   P   IIWT   K L   + + L   G   +  I+     D G
Sbjct: 22685 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22744

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y    KN +G    S  V V D+P
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDSP 22769



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)

Query: 604  KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
            K SR +E +  V   + P   + ++ L+ L V  G+++ +   V+G P P++ W      
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +++ +    E    + ++ I +    DTGTY  EA N  G  R  AV+ V
Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7406



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)

Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
            K +  L V  G+       + G P+P++ W K D  +++ +   I+ +     ++ I D 
Sbjct: 7323 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7381

Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
               D   Y  +AVN  G AT   E+ V
Sbjct: 7382 KRSDTGTYIIEAVNVCGRATAVVEVNV 7408



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
            P PP      + I  ++  L W     DGGS + +Y +E  D   K W+ +  T + T  
Sbjct: 7712 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7770

Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
             V  L     Y FRV A N  G S+
Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSD 7795



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P  IL P  + IK G   + E  V G P P   W +    + +     +      +  L+
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12585

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I  V  +D G Y+  A N SG     +++ V
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
             ++  +A N +G +S    L V  +A  + + P+F  +     V+ G+D  +     G P 
Sbjct: 15746 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15804

Query: 543   PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             P +TW  +  P+ Q  R   E+    + L I+DA  ED G Y     N+ G+   +  V 
Sbjct: 15805 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15864

Query: 600   VHEKKSSRKSEYLLPVAPSKPTAPI 624
             V +K             P  PT P+
Sbjct: 15865 VLDK-------------PGPPTGPV 15876



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 20/81 (24%), Positives = 39/81 (48%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV  G+  +    I G+P P + W+KG+  L  +AR+ +   +    L +    + D G
Sbjct: 16181 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16240

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y     N +G+ S++  + +
Sbjct: 16241 NYILKAKNVAGERSVTVNVKV 16261



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             ++ G   K E  + G P+P +TW ++G P+    R  +   +  T +L I   H++D G+
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16927

Query: 104   YTCEATNGSGARQVTVEL 121
             Y     N  G +  ++E+
Sbjct: 16928 YGITVANVVGQKTASIEI 16945



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             ++P          +  G   + +  + G P P + W KD + ++++    ++ +   +  
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17996

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   DD  KYT  A NS G AT    +IV
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/74 (31%), Positives = 33/74 (44%)

Query: 639   QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
             Q+ + V   G P   V W  +G  ++E+   +     T  SL I+E   ED GTY     
Sbjct: 19039 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19098

Query: 699   NSAGEVRTQAVLTV 712
             NSAG +     + V
Sbjct: 19099 NSAGSITVPITIIV 19112



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 711   TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
             +V EP + T P  +      PR          +    G+ + I+  IAG P P + W +D
Sbjct: 19395 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19454

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             G  + ++    E++  ++   L +K       GQY + LKN  G  S  V+
Sbjct: 19455 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19504



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F+K + D  V EG+ A  +C++    + +V WFK+   I +S+ ++I  D      L+I 
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5972

Query: 1820 DVCGDDDAKYTCKA 1833
            D   +D   YTC A
Sbjct: 5973 DCTPEDIKTYTCDA 5986



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + ++ G T +   RV+G PEP +TW + G+ +    R  L   +     L I      D 
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11604

Query: 102   GKYTCEATNGSGARQ 116
             GKY   A N SG  Q
Sbjct: 11605 GKYIISAKNSSGHAQ 11619



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V+  QT++    V G P+P++ W  EG  + R E  +++ +D     L + +A   D G 
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11606

Query: 485   YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
             Y  +A N+ G    S  + V       + L V  V     ++  +  +  G   +    V
Sbjct: 11607 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11666

Query: 538   RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
                           +P Q   S   + V +  I+ + L  +   +   AEN +G      
Sbjct: 11667 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11710

Query: 597   WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
               T+  K        +L + P  +P  P       +L + D  +  + ++       G  
Sbjct: 11711 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11758

Query: 651   PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
             P   +  H    ++ S+D+    +G+  +    +          +  +  N  GE   V+
Sbjct: 11759 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11816

Query: 706   TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
             T+ V+  +   D  +P    K   V T   G ++ +   + G PFP V W +D  A    
Sbjct: 11817 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11873

Query: 764   DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              +   ++    D     L K +    G+Y +   N  G
Sbjct: 11874 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11911



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             VK    V     V G P P V+W  +GT ++  EG I++        L L     +DSG 
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 12993

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y+ TA N+ G  S +  L+V
Sbjct: 12994 YTITAENSSGSKSATIKLKV 13013



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)

Query: 490   SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             S++ G ++    +++ R+++    P F   +    V  G+ F L+  V G P+P I WL 
Sbjct: 17236 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17289

Query: 550   NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
               + I+ + + CE       A L ++DA+  D G Y   A N  G  S    V V ++  
Sbjct: 17290 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17346

Query: 606   SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
                        P  P  P+ + G++  K
Sbjct: 17347 -----------PGPPEGPVQVTGVTSEK 17363



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)

Query: 20    DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
             DP+ V    L     E P  IL     R   IK G T +    ++G P P+VTW +  + 
Sbjct: 10827 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10886

Query: 73    ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               +  R  +D    G+   + +A H ED G Y+    N +G++ V+V++ V
Sbjct: 10887 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10934



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
             VK   T++    V G P PEVAW    + T + R    +++   A S    L KA+  D 
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11899

Query: 483   GTYSCTASNAQGQLSCSWTLQV 504
             G Y  TA+N  G      T+ V
Sbjct: 11900 GKYVVTATNTAGSFVAYATVNV 11921



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)

Query: 598   VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
             V V+EK  S      +P VA      P      S   V  G  + + V +SG P P + W
Sbjct: 16832 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16891

Query: 657   LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
               +G  ++++   +        +L I+E   +D G Y     N  G+   +  ++T+ +P
Sbjct: 16892 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16951



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
             KD  V+  G+ FVL+  +RG P+P + W  +G+ ++   AR   ++ + +  L ++D + 
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y     N  G  S    V V ++             P  P  P+ + G++
Sbjct: 18402 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18443



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
             Q+  V+   +++      G P P   W     P        +++       L +      
Sbjct: 21993 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 22049

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y+ T  N  G  S ++T++V         +   +V    ++++ D  +++G   + 
Sbjct: 22050 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 22109

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                V      R +W       Q     C   + +++              LAE       
Sbjct: 22110 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22149

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              SA   V+E       E   P+  ++  AP        L V+D S+ +  +         
Sbjct: 22150 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22193

Query: 654   VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
               WL   H+G            Q+  DF  E   T Q +  ++ +  +    +  +A N 
Sbjct: 22194 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22251

Query: 701   AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
             AG    +   +   ++EP  + T        + +T   G    I   I+G P P V W  
Sbjct: 22252 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22311

Query: 757   DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             +   L K+T    +   +D  TL +K      +G+Y + L+N  G  +  V++++     
Sbjct: 22312 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22370

Query: 817   RAL-PRGREPASCED-LCGGGVGADGGGSD 844
                 P      S E  +   G   DGGG++
Sbjct: 22371 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
            G  AKF   ++  P  +  W + G+ I    +    C IR +    SL I      D G+
Sbjct: 4476 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4531

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            YTC+A+N  G+   T  LTV        G+  V K L +R   P  E
Sbjct: 4532 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4574



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
            S +D SQ  +EA+   +E K  V    PYF+  ++D   VE       C+I    D  V 
Sbjct: 5619 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5677

Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            WFKD + I+ S++  I  D      LI+      D  +YTC
Sbjct: 5678 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5717



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)

Query: 21   PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
            PSR    + ++   EAP   L  +    L +K G   +    V G PEP++TW +    +
Sbjct: 7300 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7359

Query: 74   TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                R  ++  +    ++ I      D G Y  EA N  G     VE+ V
Sbjct: 7360 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E + +        +P P V+W  +G  V+  +  + +  D  S +L + K+   D+G 
Sbjct: 8026 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 8084

Query: 485  YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
            Y+ T  N  G  + S  ++V       + +   ++  S   +  +    +G   +L   +
Sbjct: 8085 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8144

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
                  R T++    P+    +     V     +D +P     +   A N +G       
Sbjct: 8145 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8188

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                        E   PV    P  P       D++V + +   MT+  +  PP     L
Sbjct: 8189 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8232

Query: 658  HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
            ++G             +G +    C + + P    TYT +      E    VR +    +
Sbjct: 8233 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8290

Query: 713  QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
             EP   T P     P          S+    G  + +  +I+G P+PT+ W++D
Sbjct: 8291 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8344



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L I+ G      GR  G P+P+V+W ++   +    R  +      T +L        D 
Sbjct: 10456 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10514

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             GKY     N +G+R+   ++ V      + G PV   +    F     +     W     
Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10566

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
                +K+   ++++ ++G+            V     +   + + +VS   +    +  IH
Sbjct: 10567 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615

Query: 222   GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
               N    G+   LV +     SM A+   +  D+ ++  V E    ++        D  K
Sbjct: 10616 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10668

Query: 274   EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
              +TN I ++ +  S   A  +K+                C    R  +        P PP
Sbjct: 10669 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10728

Query: 318   RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
              +   +K    K SP   P+       S  +T Q  R     +  G  V     G+E  R
Sbjct: 10729 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10788

Query: 374   PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
              A   P + P T+    G +D    K     +   G+ D A        K   +P     
Sbjct: 10789 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10848

Query: 421   -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                  + Q +K   T++    + G+P P+V W  E       +  I+V    GS  L + 
Sbjct: 10849 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10905

Query: 476   KARTRDSGTYSCTASNAQGQLSCS 499
              A   D G YS T  N  G  + S
Sbjct: 10906 NAAHEDGGIYSLTVENPAGSKTVS 10929



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 23/81 (28%), Positives = 34/81 (41%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VVK G   RF   I G P P   W      ++     +V   N   VL I    + D G
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11207

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y   V N +G  +++  L++
Sbjct: 11208 EYQITVSNAAGSKTVAVHLTV 11228



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             +++ A + +     +  P  V      EAP   L     + + ++ G +A+     +G P
Sbjct: 17621 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17680

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P++TW R     T   +  ++ G+  T  L I      D GKY  +  N SG++   V 
Sbjct: 17681 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17737

Query: 121   LTV 123
             + V
Sbjct: 17738 VKV 17740



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L L   VS  PP  I W+  G  L +   I  ++  SL  + ++K    D G
Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23141

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y   A+N +G+   +  V V D P
Sbjct: 23142 KYTIEAENQSGKKSATVLVKVYDTP 23166



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
            P F    +SV    G +      I+G P P V W RDG+ +   T    ++  ++    L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
             +  V   ++G+Y +   N  G+ +    L+++  +A        P   + L    +   
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116

Query: 840  GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
             G   R      G P     +    DG +++  L  ++            E         
Sbjct: 117  QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 894  QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
             ++  + +G+  ST  L     +E+PA++     +   Q+     +  E+K+ +    D 
Sbjct: 175  SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231

Query: 954  RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
            RS+    +   G +   +P K PP  P  P  RS     +  K +L  +   S       
Sbjct: 232  RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287

Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
                S  P+ + +   P  PV +  PA
Sbjct: 288  ---HSPSPVRHVRAPTP-SPVRSVSPA 310



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
            E V  + P  KP       D+ V+EG            P P V W KD + ++ S    +
Sbjct: 8004 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8063

Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   +  L +      D   YT    N LG AT +  + V
Sbjct: 8064 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
            SV     ++ G+   +   V G PVP   W      +   R   +     +EL I+DAL 
Sbjct: 8737 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8796

Query: 576  EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
            +DHG Y   A N+ G    +A V V +         +L + P      + L   SD +  
Sbjct: 8797 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8851

Query: 636  DGSQVT 641
             GS++T
Sbjct: 8852 GGSEIT 8857



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
            G  + I   I G P P   W  DGKA    KD  H        E  +N  V  +++ + +
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9510

Query: 786  PWHAGQYEILLKNRVGE--CSCQVSLM 810
              H G+Y I  KN+ G+   +C+V +M
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVM 9537



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)

Query: 668   DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             D HFE  G    H    + +     G ++ E   S G +  +    V  P     P +  
Sbjct: 16123 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16179

Query: 726   KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
                ++    G+S  +   I G P PT+ W++  + L  +T   E+   +   +L +K   
Sbjct: 16180 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16235

Query: 786   PWHAGQYEILLKNRVGECSCQVSL 809
                +G Y +  KN  GE S  V++
Sbjct: 16236 RVDSGNYILKAKNVAGERSVTVNV 16259



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + V  G  + +  +V G P P++ W   G  +   +     Q   +  L I+E    D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605

Query: 692   TYTCEAWNSAGEVRTQAVLTV 712
              Y   A NS+G  +  A++ V
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV 11626



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             SV A  G+ V +     G P PTV W +D K L  D   + +   +    L + +V    
Sbjct: 20908 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20966

Query: 789   AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
              G+Y + ++N VGE           SS  ++     PA+C+ L
Sbjct: 20967 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21000



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L+   +G P P I+WL +G P+   ++ R +       L I++A  E  G YT +
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21265

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
              +NA+ +++    V             L P  PSKP  PI
Sbjct: 21266 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21292



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            G E+  T   + PAP   P    PP ++   ++  V  GESV L   ++G    T TW +
Sbjct: 875  GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               QI+ S   ++      ++L I  A  E  G +T    N+ G+      L V
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 614  PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            PV  ++P  P    + +     +++M G  + +   V+G P P  +W     E+ + +  
Sbjct: 8720 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8778

Query: 670  HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
              +  GT+  L I++   +D G Y   A NS G
Sbjct: 8779 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
             L +K G T + E  VRG P P+V W   ++   +T   R  +D     + FSL       
Sbjct: 11839 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11896

Query: 99    EDRGKYTCEATNGSGA 114
              D GKY   ATN +G+
Sbjct: 11897 SDGGKYVVTATNTAGS 11912



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)

Query: 403   IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
             IP EG+ D+   K      +  ++   T++    V G P P++ W      +R + G ++
Sbjct: 13317 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13369

Query: 463   VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
             +       +L        D+G Y  T  N+ G+   +  ++V         + V E++  
Sbjct: 13370 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13429

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
              + V  +  +I+G   ++   V+     R +W         +  T E       + +   
Sbjct: 13430 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13480

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
                  +   AEN  G         + +   +R +     V  S+   P+      DLKV 
Sbjct: 13481 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13521

Query: 636   DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
               S+ + ++   G   P       G+ I     DF  E+   Q    SL +Q    + T 
Sbjct: 13522 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13575

Query: 692   ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
                 T+   A N  GE  T + +TV    D   P    K        A    +  +   I
Sbjct: 13576 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13634

Query: 745   AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
              G P P+V W +    L  DT    V  +    TL++   Q   AG+Y I LKN  G   
Sbjct: 13635 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693

Query: 805   CQVSL 809
               +S+
Sbjct: 13694 GTISI 13698



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             PAF L      +  G   K +    G P P VTWH++  P+    R   +        L 
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15834

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
             I     ED G Y  + TN +G    T+ + V        G   + +   D  +       
Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15889

Query: 153   PSIWGECPPKF 163
                WG  PPK+
Sbjct: 15890 ---WG--PPKY 15895



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD  VV  G   R +  + G P P + W + D+ I ES   +I  + D    LI+ D   
Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17318

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y  +A N  G
Sbjct: 17319 IDGGQYILRASNVAG 17333



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 22/83 (26%), Positives = 37/83 (44%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +  K G        I+GRP P+VTW    + L+ + RVS++       L +    + D G
Sbjct: 22285 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22344

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y   + N +G  + S  + + G
Sbjct: 22345 RYFLTLENTAGVKTFSVTVVVIG 22367



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)

Query: 541  PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
            PV    W+ +N +PI+  +   E GV        +P+        A NA+G         
Sbjct: 7953 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7996

Query: 600  VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
                + S  SE ++   P  KPT  +      D+ V++G ++++ V     P P V W  
Sbjct: 7997 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050

Query: 659  NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
            +G E++ S+    +       L + +    D G YT    N  G       V  +  P  
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8108

Query: 718  GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
               P    K   +T S       SC +  +P       P +H++ + +   + T +  V+
Sbjct: 8109 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8158

Query: 772  QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              E+  +  +K + P     + +   N+VG
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8188



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 620  PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
            PT  + L    D +KV  G  V +   V+G P P++ W  N   I++  D          
Sbjct: 9023 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9082

Query: 673  QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
            +   +  L I +   ED GTYT  A N  G V
Sbjct: 9083 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9114



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/73 (27%), Positives = 33/73 (45%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V++K G+  R    ++GRP P + W K    L+ +A++ +   +    L      + D G
Sbjct: 15099 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15158

Query: 230   VYTCLVVNGSGKA 242
              YT    N  G A
Sbjct: 15159 AYTLTATNPGGFA 15171



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
             +AP   L P+    + +  G T   E  +RG P P V W ++G+ +  +  R  +   I+
Sbjct: 18331 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18390

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              T +LV+      D G+Y  + +N  G + + + + V
Sbjct: 18391 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18426



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 617   PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
             PS+ T PI ++        + D+K  D      G  + +   ++G P P + W  +G EI
Sbjct: 19399 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19458

Query: 664   QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             +E              L +++    DTG Y     N AG
Sbjct: 19459 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19497



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/83 (24%), Positives = 38/83 (45%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             +  G+ L ++  V   P   + W  +G  ++    + ++      S+ +  A  + RG+Y
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21657

Query: 1169  KCVAKNDAGQAECSCQVTVDDAP 1191
                AKN +G A+   +V V D P
Sbjct: 21658 TVEAKNASGSAKAEIKVKVQDTP 21680



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
            ++++ G   R    + G P P  VW K++  + + R   +  D  G  S LII D    D
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8798

Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
              +Y   A NS G     A + V
Sbjct: 8799 HGRYVITATNSCGSKFAAARVEV 8821



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T  +GQ++ I   + G P P + W ++GK L ++    +++Q+     L +K+      
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11604

Query: 790   GQYEILLKNRVG 801
             G+Y I  KN  G
Sbjct: 11605 GKYIISAKNSSG 11616



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L  +V G P+P ++W  +G   +P +  +   +  +  L +     +D G YT  
Sbjct: 12938 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12997

Query: 585   AENALGQVSCSAWVTVHEK 603
             AEN+ G  S +  + V +K
Sbjct: 12998 AENSSGSKSATIKLKVLDK 13016



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)

Query: 19    VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
             VDP R+   P  +          + +  G + K +  + G P P + W +  Q +++  R
Sbjct: 16166 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16217

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
               +      T SL +      D G Y  +A N +G R VTV + V        G  V+S 
Sbjct: 16218 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16276

Query: 139   TLGDR 143
                ++
Sbjct: 16277 VTAEK 16281



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
             V+   + +      G P PE+ W        R+EG    +V  + G +Y  L +      
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17716

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y     N+ G  S   T++V       + LAV EV    + ++ +  +I+G   V 
Sbjct: 17717 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17776

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                +      R           YA  + +       +++        +  +AEN  G   
Sbjct: 17777 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17824

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                 V V    + + +E   P  P K T            + D SQ + ++       PE
Sbjct: 17825 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17865

Query: 654   VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
                 H+G           + +GT+         +C   V    +G    +  +A+N  G+
Sbjct: 17866 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17921

Query: 704   VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
                + +       D T QP       + +   G+ + I   + G P P + W++DG+ L 
Sbjct: 17922 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 17980

Query: 763   KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             K T    V +      L +K+      G+Y +   N  G  +  +S+++
Sbjct: 17981 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)

Query: 1740  DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
             D S +    +A+E+   +P F   S+  + L V  G++        G P P V+W K D 
Sbjct: 19795 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19853

Query: 1797  SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
              +R   +       D   SL I +   +D  KYT    N L  A+ T  L+V+ ++
Sbjct: 19854 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19904



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 38    PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
             P   + ++ G+  K +  + G P P+VT  R+G P+ +  RF  +       ++ +    
Sbjct: 20110 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20168

Query: 98    EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
               D G+Y   A N SG  +  + + V        G  V+S
Sbjct: 20169 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G+S+ I   + G P P V W +DG  + K   + E+       +L ++     H G Y +
Sbjct: 21601 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21659

Query: 795   LLKNRVGECSCQVSLMLQNSSARAL 819
               KN  G    ++ + +Q++  + +
Sbjct: 21660 EAKNASGSAKAEIKVKVQDTPGKVV 21684



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)

Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
            +  H G        + +   P      + V V EG+    +C+V+  P   + W LNG+ 
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834

Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
            ++ +K   +  +G +  + I      D G  K  A+N  G  E   ++ +       S  
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893

Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
             +APE    RP+  +      + +     +P   T  K  +  +  +    +KV   ES 
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949

Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
            EL  K          + IT   +K RK+ +  E +                   K   +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009

Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
             G K+TI         L+   E    +  +    +G    A   + VV KPDP       
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063

Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
                       WY +            IE  D     W E   C      ++D+  +   
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101

Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
               V+AIN+ G +        Q  +L T  ++ ++     KD +   + +  EP V  + 
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161

Query: 1452 VTINTEQKVSDFY 1464
                 E    D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)

Query: 935  PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
            P+ V E + K+   Q+ DFRSVL            + P P+   P+F     GK +   +
Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916

Query: 995  NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
                  +T   K V   K             + + K  E  + + +     T +    A 
Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967

Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
                LKS  K+E  +++      +  H     T+ EK++   E + T P FK        
Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027

Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
                    +++Q   V +G     + +V   P     W  NG K  ++ +      E ++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
            C + I     ED       A N AG+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + +   VSG PPP V W  N NE    ++   E      S+ I+       G Y+  
Sbjct: 10167 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10224

Query: 697   AWNSAGEVRTQAVLTV 712
             A N AGE +   ++ V
Sbjct: 10225 AKNEAGERKKTIIVDV 10240



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
             T RD+  V  G   R   +++G P+P++ W K+ +  +RE R   +D  +D     L I 
Sbjct: 11541 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11597

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCTA 1844
             +    D  KY   A NS G A  +A
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSA 11622



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 1749  VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
             V  E+  VK    K + DL+      V  G   R +  + G P PEV W KD  +   +R
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874

Query: 1803  HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               ++  D   + S   ++     D  KY   A N+ G     A + V
Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 22/92 (23%), Positives = 40/92 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G ++ +   V G P P   W    +E+  S      +  +   L I++V  +D+G
Sbjct: 12536 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12595

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
              Y+  A NS+G    +  + V +     QP F
Sbjct: 12596 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12627



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             + +  G + R    I+G P PEV W K D  IR++    +        SL++ +V   D 
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16636

Query: 1827  AKYTCKAVNSLG 1838
              KYT    NS G
Sbjct: 16637 GKYTLTLENSSG 16648



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 1758  PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
             P     +   EVV+   G++ +    I G P P + W+KDD+ ++ +    ++   D   
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20556

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
             S++I D    +   Y  K  N++G A+ T
Sbjct: 20557 SILIKDADRLNSGCYELKLRNAMGSASAT 20585



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V  + G   +    I+G+P P + W K +  LQ +A V V     +  + I   ++ + G
Sbjct: 20510 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20569

Query: 230   VYTCLVVNGSGKASMSAELSIQGLD 254
              Y   + N  G A  SA + +Q LD
Sbjct: 20570 CYELKLRNAMGSA--SATIRVQILD 20592



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)

Query: 143  RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
            RF A   E R  +     PK  T    +VV  G+           P+ +  W K N PL 
Sbjct: 6610 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6669

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + +E+   ++LE     + D G Y  ++ N  GKA     L +
Sbjct: 6670 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6714



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 172  VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
            V+EG       KI G P P +TW K   P +P  +  V   +  N + V     L I   
Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9814

Query: 224  NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
             + D G+YT   VN  G AS    L++ G
Sbjct: 9815 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9843



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
             G    L   ++G P P++TW    +     AR       ++L I++A  ED G Y+   E
Sbjct: 10861 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10920

Query: 587   NALGQVSCSAWVTVHEK 603
             N  G  + S  V V +K
Sbjct: 10921 NPAGSKTVSVKVLVLDK 10937



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
             A+N  G +S  +  T   +    K EY  P     PT          L +  G  + +  
Sbjct: 13978 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14028

Query: 644   VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             + + G P P+  W   G +I+ S+        T   L I+    +D G YT  A N  G 
Sbjct: 14029 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14088

Query: 704   VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
                   +TV +      P  IS   +  A+L
Sbjct: 14089 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14119



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             V  GS + + + +SG P P+V    +G  ++ +  F+ E      ++ ++E    D G Y
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20175

Query: 694   TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
                A NS+G  +    ++ +  P   T P  IS
Sbjct: 20176 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)

Query: 1743  QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
             +AF   + +E P ++P    T    +++    GS    D  I G P P+V W  ++  ++
Sbjct: 22259 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22317

Query: 1800  ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             E+    I   +D   +L + D    D  +Y     N+ G  T +  ++V
Sbjct: 22318 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
            NC+    G  D    N K S      P      + L+DV V  G+     C++S +    
Sbjct: 5795 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5853

Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
            + W L GK L+ +  ++   EG + ++++     ED G  +  AK+
Sbjct: 5854 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5899



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 438   SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
             SG PKP+V+WF +   V  ++    +     +  L  +KA+  DSG Y     N+ G   
Sbjct: 10471 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10529

Query: 498   CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
                 + V       V P SF  V KD  VI
Sbjct: 10530 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10559



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             ++  + G++  +   + G P PT+ WLR  K + +++   E+   +    L++K      
Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17320

Query: 789   AGQYEILLKNRVGECSCQVSL 809
              GQY +   N  G  S  V++
Sbjct: 17321 GGQYILRASNVAGSKSFPVNV 17341



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 161  PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
            P   T L   V +EG +   +  IT   +  V W   N  +    +    +      L I
Sbjct: 4368 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4425

Query: 221  HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
              VN +D  G Y C  +N SGK + SA+L++
Sbjct: 4426 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4456



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
            T S ++  + E    ++  +A N  G  + ++ L V                + D    P
Sbjct: 8979 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9023

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
             ++ R S+ G+           + VK G+       +TG P P++ W K    ++     
Sbjct: 9024 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9073

Query: 205  ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
                +  VS       L I    ++D G YT    N  G    +  + +    S  R+  
Sbjct: 9074 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9133

Query: 261  VRETKA 266
            V + KA
Sbjct: 9134 VTDIKA 9139



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G +V     I G P PT  W  DG  + K   H+ V  +     L +K       G+Y+I
Sbjct: 11153 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211

Query: 795   LLKNRVGECSCQVSL 809
              + N  G  +  V L
Sbjct: 11212 TVSNAAGSKTVAVHL 11226



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
             EAP  +L P     L IK G T       + G P P+ +W + G+ I       +     
Sbjct: 14002 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14061

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              +   + +A  + D G+YT  ATN  G +   V++TV
Sbjct: 14062 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14097



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
             G +  ++  V G P P +TW    Q ++  +       A    L+I + +  D G Y   
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
             A N +G+V     + VH+              P  PT PI
Sbjct: 14768 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14794



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             I+ G + +    ++G P P+V W +    I      ++D     T SLV+  V+  D GK
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16638

Query: 104   YTCEATNGSGARQVTVELTV 123
             YT    N SG +   V + V
Sbjct: 16639 YTLTLENSSGTKSAFVTVRV 16658



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P+  LP     +K     K +   +G P+  V W ++GQ +    R  +    +   SL 
Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19081

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I    +ED G Y    +N +G+  +TV +T+
Sbjct: 19082 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19110



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 1782  EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P V W KD++++     + I+ + D +  L I  V  +D  KY     N +GE
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20980



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 1084  TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
             +T    ++  +G  P  +    D+ + EGK L + C  + +P   + W+  G+ + + + 
Sbjct: 26943 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27002

Query: 1143  -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
                 +     L ++ I     +D GLY     N+ G    +  + +
Sbjct: 27003 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F + L ++ V+E   + L C+VS  P A +IW    + +  T    +  EG    + I+ 
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6151

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
            A  ED G Y C                                 R P S         +D
Sbjct: 6152 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6170

Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
              VK            +  + I  P++ ++  GE  E    ++  +     W +  K ++
Sbjct: 6171 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6220

Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
              +   V        L +  A  +  G Y ++V    G+ +A  +LTV++K
Sbjct: 6221 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6267



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 16/82 (19%), Positives = 37/82 (45%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             ++ ++ G+    + + +G+P+P+V+W K    +    R  +        LE     + D 
Sbjct: 10455 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10514

Query: 229   GVYTCLVVNGSGKASMSAELSI 250
             G Y  +V N +G      ++++
Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV 10536



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)

Query: 619   KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
             KP   + L G+  L V  G  + +   V G P PEV W    +  ++  S     + R  
Sbjct: 11828 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11885

Query: 677   QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                  + +    D G Y   A N+AG     A + V
Sbjct: 11886 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
             +  +A+NA G +S  +  T      + K E  LP     P      +    + V  G   
Sbjct: 17221 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17271

Query: 641   TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              +   V G P P + WL    EI+ES     +    +  L +++    D G Y   A N 
Sbjct: 17272 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17331

Query: 701   AG 702
             AG
Sbjct: 17332 AG 17333



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + +K G   K    + G P P ++W ++G  I    R  +      T  L +      D 
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19485

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
             G+Y     N +G R V V   V        G   ++    ++ S     P  +    I  
Sbjct: 19486 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19545

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
                 K  T      + EG++   SCK+T         LKGN  +            +P  
Sbjct: 19546 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19598

Query: 206   RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
              V++   +   V      LEI  V ++ + +  C     S   S  +   I+  +  +  
Sbjct: 19599 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19656

Query: 260   FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
             +VR  K    D+R + T +      E ++ +  AA  S     S   R   P +     P
Sbjct: 19657 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19712

Query: 315   QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
              PP + K+ +S K +   A   P+    +          + +       + S  G E   
Sbjct: 19713 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19772

Query: 374   PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
                   A +  R      +G+ D  S +++ +I  E + +  F       ++  VK   +
Sbjct: 19773 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19831

Query: 431   VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
                     G P P V W    T +R +   ++  +   S  L +  A   DSG Y+ T  
Sbjct: 19832 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19888

Query: 491   NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
             N     S +  ++V          +   V K+ AV+
Sbjct: 19889 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19924



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V++G + R +  I G+P P   W K    +   A ++ SE +    L I   ++ D G
Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23831

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y  ++ N  GK ++  ++ + G
Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIG 23854



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
             P  +  +R   V  G   RF   ++  P  EV W+ +   ++ES   +I Y +  G  +L
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26059

Query: 1817  IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              I D   DD   Y     N  GEA+  A L V
Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   + D++V E   A+F+C++   P     W K  Q I     F++  D   + S++I 
Sbjct: 5470 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5527

Query: 1820 DVCGDDDAKYTCKA 1833
                +D+AKY  +A
Sbjct: 5528 SAAFEDEAKYMFEA 5541



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             R+VV  G + R    ++G+P P VTW      L   A +  +  +   V  I    +   
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10218

Query: 229   GVYTCLVVNGSGK 241
             GVY+ L  N +G+
Sbjct: 10219 GVYSLLAKNEAGE 10231



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             ++ G   +    VRG P P+VTW + G    +  G   L+D        LVI     +D 
Sbjct: 12246 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12301

Query: 102   GKYTCEATNGSGARQVTVELTV 123
             GKY+    N +G + V V + V
Sbjct: 12302 GKYSLTLVNPAGEKAVFVNVRV 12323



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             L V  G+    D  + G P P V W KD   ++ +   ++    +  C+L +  V   D 
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991

Query: 1827  AKYTCKAVNSLGEATCTAELIV 1848
               YT  A NS G  + T +L V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 615   VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             VA     AP + L+GL DL  +  + S   + + + G P P V W    + +        
Sbjct: 13600 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13659

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
             E      +L + +    D G YT    N AG +  T ++  V +P   T P
Sbjct: 13660 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13710



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)

Query: 142   DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
             D + AP +   P+I          K G  +V        +  I G+P P+ +W K    +
Sbjct: 13999 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14048

Query: 202   QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             +PS    ++      +L I    + D G YT    N  G
Sbjct: 14049 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G ++ +   I+G P P V   RDG  L K T  F      +  T+ LK+     
Sbjct: 20113 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20171

Query: 789   AGQYEILLKNRVGECSCQVSLML 811
             AG+YEI   N  G     +++++
Sbjct: 20172 AGRYEITAANSSGTTKAFINIVV 20194



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
             V+++   ++ V+K  A   G    L+  + G P P I W  + + +Q     C      +
Sbjct: 20499 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20555

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
             A + I+DA   + G Y     NA+G  S +  V + +K
Sbjct: 20556 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20593



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
            V   P+    W   G PV   +  +   E+ G  Y             Y   A N QG  
Sbjct: 7252 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7298

Query: 497  SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
              S  T +++ +   E    F  V  L    V  G    L  +V G P P+ITW      
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358

Query: 554  I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
            + Q  R T E     + + I D+   D GTY   A N  G+ +    V V +K
Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7411



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 16/67 (23%), Positives = 28/67 (41%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G    +   + G P P + W+    E+  +     +      SL +++    D+G Y  +
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16245

Query: 697   AWNSAGE 703
             A N AGE
Sbjct: 16246 AKNVAGE 16252



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)

Query: 395   VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
             +SK ++   P+  + +   P+    P+ ++   V   +T +   +V G P P + W L G
Sbjct: 17232 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17290

Query: 452   TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
                  +    E+        L +  A   D G Y   ASN  G  S
Sbjct: 17291 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17336



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++  AT +    ++G PEP+V W +    +T   +      +  +F+ LVI  V   D G
Sbjct: 18747 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18802

Query: 103   KYTCEATNGSGARQVTVELTV 123
             +Y     N SG++   V + V
Sbjct: 18803 RYNLTLENNSGSKTAFVNVRV 18823



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             +KP          V      + D   +G P   V W KD Q+++E+    +   +    S
Sbjct: 19021 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19079

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   +D   Y     NS G  T    +IV
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            ++D  V E     F+C++      +  WF+++++I +S  + I   +D   +L I D   
Sbjct: 6274 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6331

Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
            DD A Y     N  GE     A LIVE
Sbjct: 6332 DDQANYNVSLTNHRGENVKSAANLIVE 6358



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 411  SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
            +A PK ++  Q   V   + +         PK E  WF E  P+  +  +I+   +  S 
Sbjct: 6625 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6681

Query: 471  YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
               +L+A+  D G Y     N  G+      L+       V  L V E      S+  + 
Sbjct: 6682 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6740

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLL 549
             + +G   ++   V    + R TW+L
Sbjct: 6741 PLTDGGSKIIGYVVERRDIKRKTWVL 6766



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
            G+  L   S  +K  +S DPS +   PLT   AF+ P  +L   K+G        +    
Sbjct: 6987 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7044

Query: 58   ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
               GYP P  TW    + + +G R  +   +     LVI      D+G YT +  N
Sbjct: 7045 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7099



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
             G + VK G   R    + G+P P+V W K      L  S RV +  +       +    +
Sbjct: 11837 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11896

Query: 226   DDVGVYTCLVVNGSGKASMSAELSI 250
              D G Y     N +G     A +++
Sbjct: 11897 SDGGKYVVTATNTAGSFVAYATVNV 11921



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 1761  SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
             S+  + + V  G +AR     +G P PE+ W +++    +    ++  ++  N + +  D
Sbjct: 17656 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17711

Query: 1821  VCGDDDA-KYTCKAVNSLG 1838
              C  +DA KY  K  NS G
Sbjct: 17712 NCDRNDAGKYILKLENSSG 17730



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)

Query: 21    PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
             P  V    + E P + L  R    + +++G   +    ++G P P   W + GQ I+   
Sbjct: 23750 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23807

Query: 78    RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
             R ++      T  LVI      D G Y     N  G + V +++ V GS
Sbjct: 23808 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23855



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G  + I   ++G P PTV W  + + L ++     +       ++V+K  Q  H 
Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10218

Query: 790   GQYEILLKNRVGE 802
             G Y +L KN  GE
Sbjct: 10219 GVYSLLAKNEAGE 10231



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)

Query: 537   VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             +RG PVP   W  +G  I   ++     +   + L I++ L  D G Y     NA G  +
Sbjct: 11162 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11221

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              +  +TV +              P  PT PI         ++D +   MT  +S  PP +
Sbjct: 11222 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11258



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
             G A R +  + G P P + W KD + +  +   +I    D + +L+  D    D   YT 
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15162

Query: 1832  KAVNSLGEA 1840
              A N  G A
Sbjct: 15163 TATNPGGFA 15171



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)

Query: 20    DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
             +P+ V   P  E    +LPP         + + I+   T +    ++G P P+V W R+ 
Sbjct: 15469 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15526

Query: 71    QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                   G  L    I  T S   L++  V+  D GKY     N SG++   V + V
Sbjct: 15527 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15576



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G  + + V + G P PEV W     EI+++         T  SL +  V   D+G
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16637

Query: 692   TYTCEAWNSAG 702
              YT    NS+G
Sbjct: 16638 KYTLTLENSSG 16648



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)

Query: 17    LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
             +++ P  V  + +T E     +P   + ++ G     E   +G P+P ++W ++G P+  
Sbjct: 21175 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21234

Query: 76    GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                F+         +L I    +E  GKYT    N     ++ V +TV
Sbjct: 21235 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21279



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)

Query: 1745  FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
             + E++AE    ++P     I DLE+ +          G++ R    + G P P + W K 
Sbjct: 23056 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23110

Query: 1795  DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
              Q I  +    ID  E  +  LI+  V   D  KYT +A N  G+ + T
Sbjct: 23111 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23157



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   + D  V EG  A F C++  +    VVWFK+D  +  SR   I   E     L + 
Sbjct: 5204 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5261

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +V  DD ++   +    + E + TA+L V
Sbjct: 5262 EVTLDDISQIKAQ----VKELSSTAQLKV 5286



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   ++D+   E  +A F  ++  + +  V WFK+DQ +  +R   +  DE    S+   
Sbjct: 5559 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5616

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
            D+  DD ++   +A+    EA  T
Sbjct: 5617 DLSIDDTSQIRVEAMGMSSEAKLT 5640



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/72 (27%), Positives = 32/72 (44%)

Query: 185  TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
            TG P+P  TW  G+  L+   RV +   +    L I    + D G+YT  + N     S 
Sbjct: 7047 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106

Query: 245  SAELSIQGLDSA 256
              ++++    SA
Sbjct: 7107 EIDVNVIARPSA 7118



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 10   SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
            S IS+  ++ DP           P   L   ++ + EG         R  P P V+WH++
Sbjct: 8000 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8051

Query: 70   GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
            G+ + +  R  +          V  +V   D G YT    N  G+   ++ + V G
Sbjct: 8052 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8106



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
             G    L+  VRG P P + W  +       RS        A  ++  +  A   D G Y 
Sbjct: 11844 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11903

Query: 583   CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
               A N  G     A V V +K    ++  ++ V+  + T
Sbjct: 11904 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11942



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 40    RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
             + L ++ G T +    V+G P P++TW +    +    R  LD  I+ T F   +    V
Sbjct: 13329 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13384

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
             ++ D GKY     N  G ++ T+ + V
Sbjct: 13385 NKYDAGKYILTLENSCGKKEYTIVVKV 13411



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             VK V     S  S S DP         E P F +     + L +K GA+       RG P
Sbjct: 19785 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19842

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P V W +    + +  R  +D     T SL I   +  D GKYT    N   A  +T+ 
Sbjct: 19843 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19899

Query: 121   LTV 123
             + V
Sbjct: 19900 VKV 19902



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)

Query: 517   SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
             S + K   V  G  F +    RG PVP + W    +P    R+       +    L I++
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19874

Query: 573   ALPEDHGTYTCLAENALGQVSCSAWVTV 600
             A   D G YT   +N L   S +  V V
Sbjct: 19875 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19902



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             L V  G+  TMTV   G P P V+W     +++     + +   ++ SL I+     D+G
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19881

Query: 692   TYTCEAWN 699
              YT    N
Sbjct: 19882 KYTLTIQN 19889



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G  KL+     +  +LSV+  ++           I   R+L   E     FE  +  +  
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W+   + I    ++ ++   +  + L +  + ++D GKYT  A    G    + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
            TV G          +SK L D+                            V E Q   F 
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C++   P  +  WL+    L  +  +        + L I     DD+G YT  V      
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653

Query: 242  ASMSAE 247
            A +  E
Sbjct: 2654 AKLKVE 2659



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)

Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
            S T  +++E    + ++ +  L+ +++ K  VK              PYF+  + D   V
Sbjct: 5244 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5303

Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            E       C++    D  V WFKD + I  S  + I  D      L I      D  +Y 
Sbjct: 5304 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5360

Query: 1831 CKAVNSLGEATCTAE 1845
            C       +A  T E
Sbjct: 5361 CDCGTDKTKANVTVE 5375



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)

Query: 442  KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
            K EV W L    V  Q    ++  +   H L +   + RD G Y   A + + +      
Sbjct: 6567 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6623

Query: 502  LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
                    +  AP   +  +D  V  G+   +       P     W    +P+       
Sbjct: 6624 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6675

Query: 562  EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
             A      I +A   D G Y  + +N  G+
Sbjct: 6676 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6705



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
            + V  G+ + +   V+  P   I W+ N   + K T  + +++E      +   +SI KA
Sbjct: 9036 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9095

Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
            + ED+G Y   A N  G    +  V V D P+
Sbjct: 9096 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9127



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R+  +  G   R    I+G P P+V W K+D+        +ID    G+  L I +   +
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10910

Query: 1825  DDAKYTCKAVNSLGEATCTAELIV 1848
             D   Y+    N  G  T + +++V
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
             +D  V++ G+   +   + G P+P I+W  +G  I+  R+  E    + H    ++D + 
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19482

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y    +N  G  S +    V +K             P  P  P+ + GL+
Sbjct: 19483 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19524



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++ GA+ +     +G P P   W +    ++       D     +FS L +   +  D G
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22052

Query: 103   KYTCEATNGSGARQVTVELTV 123
             KYT    N SG++ +T  + V
Sbjct: 22053 KYTLTVENNSGSKSITFTVKV 22073



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            + D +V EG   + + K+      E VW KD Q ++ S    I  D+  +  L+I D+  
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373

Query: 1824 DDDAKYTCKAVNSLGEAT 1841
            +D   Y+   + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
            G ++ +   +   P     W  +GK  K  K  +        L    +   + I +    
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
              G Y   AKN AGQ   +C+V V D P
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKVMDVP 9540



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
             GS    D  + G P+P+++W K D+ +       + Y   G  +  +   C   D  KYT
Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22747

Query: 1831  CKAVNSLG 1838
                 N+ G
Sbjct: 22748 LTVKNASG 22755



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
            ++LE++EG  A F C I  E +P   V W +DD+++     + +  D      L++ D  
Sbjct: 6187 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6242

Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   Y    V  +G A   A L V
Sbjct: 6243 LQDMGTY----VVMVGAARAAAHLTV 6264



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 614   PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             P+      AP  + L     L +  G    +T + SG P P+V W  +  ++ E +  H 
Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495

Query: 672   EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
               + T  +L ++++  +  D+G Y     NS G
Sbjct: 10496 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10526



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
             KD  +++ G+ F L+  V G P P + W  +G+ ++   +  E  +A+    L  +D+  
Sbjct: 15096 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15154

Query: 576   EDHGTYTCLAENALG 590
              D G YT  A N  G
Sbjct: 15155 RDSGAYTLTATNPGG 15169



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
             G +  +   + G P+P++T   +G P++          AE   +++++++  D G Y   
Sbjct: 20119 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20178

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
             A N+ G       + V ++             P  PT P+ +  +++  V          
Sbjct: 20179 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20225

Query: 636   DGSQVT 641
              GSQVT
Sbjct: 20226 GGSQVT 20231



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P   + L+    +K   G+ V +   +SG P P + W  +  E+Q +     E      S
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20557

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
             + I++    ++G Y  +  N+ G     A + VQ
Sbjct: 20558 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20589



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             +P + + +  G   +    + G P P  +W   G  +    R  ++   +    L I   
Sbjct: 23371 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23429

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
                D G+YT E  N +G    T+++ +
Sbjct: 23430 TIRDTGEYTLELKNVTGTTSETIKVII 23456



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            F++ ++D+   E  + A F+C+    P  +V W+KD   + E   +++  D   +  L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +   D   Y+C  V      T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)

Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
            W K G  V+        I + S M +I  ++  K   G+ +  + A  L +   VS   +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            + +              ++D+ V+EG+ A  +CK+       V W+ +D+ I+     Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
             ++R L +V  G   R    + G P P+V W K   D  +R+    Q+D   D    L+I 
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12294

Query: 1820  DVCGDDDAKYTCKAVNSLGE 1839
             +   DD  KY+   VN  GE
Sbjct: 12295 NSTRDDSGKYSLTLVNPAGE 12314



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 728   RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
             R++    G S+ I   I G P P V W +D   L K+  + E   N + FT L++ +   
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14467

Query: 787   WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
             +  G++ + ++N  G+ S  V++ + ++    L
Sbjct: 14468 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14500



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             +D+ VV  G     +  I G P P+VVW KD + + E+             +L++ D   
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401

Query: 1824  DDDAKYTCKAVN 1835
              D  +Y  K  N
Sbjct: 18402 TDGGQYILKLSN 18413



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
             K G+    +  + G P P+VTW      +    R  +    +   +L +      D G+Y
Sbjct: 22288 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22346

Query: 105   TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
                  N +G +  +V + V G      G   VS          + E+    WGE      
Sbjct: 22347 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22398

Query: 165   TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
             T++   +V++ + G  + ++      R Q +VT L     ++ S RVS   + G+
Sbjct: 22399 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22451



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 1771  EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
             E S  R    I+G P P V W K +  +       ++     N +LI+ D    D  KYT
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13682

Query: 1831  CKAVNSLG--EATCTAELI 1847
                 N  G  E T + +++
Sbjct: 13683 ITLKNVAGTKEGTISIKVV 13701



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 19/80 (23%), Positives = 30/80 (37%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V   +T     ++ G P P+V W  +G  +      +E+        L +      D G 
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y    SN  G  S   T++V
Sbjct: 18407 YILKLSNVGGTKSIPITVKV 18426



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
             G    +   + G P P+V+W  +G E++E+     E + T  + +L +++    D G Y 
Sbjct: 18350 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408

Query: 695   CEAWNSAG 702
              +  N  G
Sbjct: 18409 LKLSNVGG 18416



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)

Query: 1733 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1779
            E L+  E+  ++  E+  EE   VK             P     + D    EG       
Sbjct: 4330 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4389

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1838
             I      EV W+ +++ +     F+   D++   +L+I  V  +D   +Y C+A+N  G
Sbjct: 4390 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4446

Query: 1839 EATCTAELIV 1848
            +   +A+L V
Sbjct: 4447 KTATSAKLTV 4456



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)

Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
            NC+   + T    K  E    A  F  K Q++ + EG+K    C +S +    + W  + 
Sbjct: 6161 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6216

Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
            KTL++     +  +G    + ++ A  +D G Y  +     G A  +  +TV
Sbjct: 6217 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6264



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R L V  G + R    I+G P PEV W KD+ +++   + +   + +    LII +    
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14468

Query: 1825  DDAKYTCKAVNSLGE 1839
             D  K+     N  G+
Sbjct: 14469 DTGKFVMTIENPAGK 14483



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
             L V  G  + + V + G P PEV W      L N   I+ +E F          L I E 
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14465

Query: 686   FPEDTGTYTCEAWNSAGE 703
                DTG +     N AG+
Sbjct: 14466 NRYDTGKFVMTIENPAGK 14483



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
             G   + +  + G P P V W K DQ +++++  +++++     +++ I++    D   Y 
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14765

Query: 1831  CKAVNSLGE 1839
               A N +GE
Sbjct: 14766 LTARNIVGE 14774



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G++  +   ++G P PT+ W +DGK L + T   E+   +    LV K      
Sbjct: 15098 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15156

Query: 789   AGQYEILLKNRVG 801
             +G Y +   N  G
Sbjct: 15157 SGAYTLTATNPGG 15169



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD+ VV+ G   + +  I G P P + W KD   I E    +I    D +  L + D   
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19482

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y     N  G
Sbjct: 19483 RDTGQYVLTLKNVAG 19497



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 19/71 (26%), Positives = 30/71 (42%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V V+ G   +    I+G+P P+VT  +  VPL+ + R +         + +      D G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173

Query: 230   VYTCLVVNGSG 240
              Y     N SG
Sbjct: 20174 RYEITAANSSG 20184



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
             G++ R     +G P P  VW K D ++      + D     + S +  + C  +DA KYT
Sbjct: 22000 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22055

Query: 1831  CKAVNSLGEATCT 1843
                 N+ G  + T
Sbjct: 22056 LTVENNSGSKSIT 22068



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 525   VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
             V +G    L   ++G P P   W   GQ I + A         EL I++A   D GTY  
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23835

Query: 584   LAENALGQ 591
             + EN  G+
Sbjct: 23836 VLENKCGK 23843


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score =  295 bits (755), Expect = 3e-79
 Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)

Query: 1097  APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1154
             AP FK++L++++V       L C+V+  P   + W   GK +     K+ I   +G    
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
             + I     +D  +Y+  A N  G    +  + V+                          
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24523

Query: 1215  GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                             P K  +P  +        +R GE V +    +G      TW K 
Sbjct: 24524 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24567

Query: 1275  RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
             +  I  + H +V  + + + L       ++  G Y +  +N+ G  Q  V L V D PDP
Sbjct: 24568 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24627

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1393
             P G    SD+   S+ L+W   + DGGS + +Y +E   +  + W  +   R T + V +
Sbjct: 24628 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24686

Query: 1394  LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1453
             L     Y+FRV A N +G S+PS+ SE T   E      +  E  D+     EV     +
Sbjct: 24687 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24743

Query: 1454  INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1513
              ++ +++ + Y I E LG G+FG V R VE  ++K +  KF K     ++  +++EISI+
Sbjct: 24744 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24802

Query: 1514  NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1573
             N   H  ++   ++FE    +VM+ E +SG ++FERI    FEL ERE + Y+ Q+ E +
Sbjct: 24803 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24862

Query: 1574  EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1633
             +++H   I H D++PENI+   +  + IK+I+FG AR+L+   + ++LF  PE+ APEV 
Sbjct: 24863 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 24922

Query: 1634  NYEPIGYATDMWSIGVICYIL--------------------------------------- 1654
              ++ +  ATDMWS+G + Y+L                                       
Sbjct: 24923 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 24982

Query: 1655  ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1702
                         +R+  ++ LQHPWL +  + +  K +   + ++Y      +K  N V 
Sbjct: 24983 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25041

Query: 1703  AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1762
             +  R+S    I      +S  G   + +    +E    VS   + AV EE  HVK     
Sbjct: 25042 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25089

Query: 1763  TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
                           + CKIE Y    +V W+   + +  S  ++I Y EDG   L + D+
Sbjct: 25090 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25134

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
                DD  Y CK VN  GE +  AEL V+ + E
Sbjct: 25135 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25166



 Score =  164 bits (416), Expect = 6e-40
 Identities = 162/691 (23%), Positives = 267/691 (38%), Gaps = 79/691 (11%)

Query: 63    QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
             +VTW+++G+ +   G F       GT+ L I+ + E D+G+Y CE +   G  +  ++  
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310

Query: 123   VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
              +            S  K+  Q     T+  +    A E   S      P   T L    
Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26365

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V    + +F+ K TG P+P   W K    +    +  +SE  G   LEIH  +  D G+Y
Sbjct: 26366 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26425

Query: 232   TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT------NSDVRKEVTNVISKESKL 285
             TC V N +G  S S +L+I+ +       V   K +       + V++E++    +  ++
Sbjct: 26426 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEI 26485

Query: 286   DSLEAAAK---------SKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
                EA ++         SK   S +   S   +          +K     +  RT  +  
Sbjct: 26486 KMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIK 26545

Query: 337   VLQKTSSSITLQAARVQPEPRAPGL--------GVLSPSGEERKRPAPPRPATFPTRQPG 388
                 T  SI  +  R+  +    G         GV   + EE +        T   +Q  
Sbjct: 26546 AF-STQMSIN-EGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26603

Query: 389   LGSQDV---VSKAANRRIPME-----GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGI 440
                + +   +SK     +  +      +  S  P F S+P+SQ + E Q V F CE+SG 
Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGE 26663

Query: 441   PKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
             P PE+ WF    P+     ++ +      + L +  A   DSG Y+  A N +GQ  CS 
Sbjct: 26664 PSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQ--CSA 26720

Query: 501   TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST 560
             T  +  L ++E  PS   VL+        D  LQ S             + Q +Q + S 
Sbjct: 26721 TASLMVLPLVE-EPSREVVLRTSG-----DTSLQGS------------FSSQSVQMSASK 26762

Query: 561   CEAGVAELHIQDALPEDHGTYTCLAENALG-------QVSCSAWVTVHEKKSSRKSEYLL 613
              EA  +      A       +  ++  ++        ++S S+++ +        S   +
Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKM 26822

Query: 614   PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHF 671
               A  +   P      SD+ + +G  +T+    +G P PEV W   G +I  QE   FH 
Sbjct: 26823 LKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHI 26882

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             E      +L I +V  +D G YT    N  G
Sbjct: 26883 ENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG 26913



 Score =  155 bits (391), Expect = 5e-37
 Identities = 124/475 (26%), Positives = 201/475 (42%), Gaps = 79/475 (16%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+   + Q   V+  +  +F   +SG P+P+++W+ E   +       +   D   + L 
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLL 3251

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-------VAPSFSSVLKDCAVI 526
            L++A   D+  Y+C A N  G  + S +L VE   V+          P+  + L+D    
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTS 3311

Query: 527  EGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTC 583
            EGQ    QC V GT + +++W    +   P ++ R T      +L I +A PED GTYT 
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 584  LAENALGQVSCSAWVTVHEKKS------------------------------------SR 607
            +A NA+GQVS +A +++   +S                                    S+
Sbjct: 3371 VASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSK 3430

Query: 608  KSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
             +E L      PV P+K       T PIF++ +S+  +  G   T++V V G P P++ W
Sbjct: 3431 INETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQW 3490

Query: 657  LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--- 713
              NG  +  S D+ F   G  HSL I     ED G YTC A N  G+    A L +    
Sbjct: 3491 FFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKG 3550

Query: 714  EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
            E H  T+                 P F+ + + +  + G   +    + G+P PTV W +
Sbjct: 3551 EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFK 3610

Query: 757  DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
            + K LC    +  +       T ++   Q   +G Y    +N +GE +C   L++
Sbjct: 3611 ENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score =  134 bits (336), Expect = 1e-30
 Identities = 111/435 (25%), Positives = 200/435 (45%), Gaps = 41/435 (9%)

Query: 396   SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
             S    +  P   +  S+ P   +  Q   V  +   KF  + +G P+P   W  +G  + 
Sbjct: 26337 STVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT 26396

Query: 456   RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
              Q G  ++ ED G  +L + K  T DSG Y+CT  N+ G +S S  L ++          
Sbjct: 26397 -QGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK---------- 26445

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
                 +KD    E Q    Q +   TP  +   ++  +  Q A  + E  ++E   Q+ L 
Sbjct: 26446 ---AIKDT---EAQKVSTQKTSEITPQKKA--VVQEEISQKALRSEEIKMSEAKSQEKLA 26497

Query: 576   -EDHGTYTCLAENALGQVSCSAWVT-VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
              ++  +   ++E      + S   + VHE+  K+S+ SE +   A  K  +       + 
Sbjct: 26498 LKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFS-------TQ 26550

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + + +G ++ +   ++G    +V W+ NG E+  SE++ +   G+  +L I++    D G
Sbjct: 26551 MSINEGQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEG 26608

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
               TC +    G V+ Q  LT+ +      P FIS+PRS   + GQ+VL +C I+G+P P 
Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSKELSDA-PAFISQPRSQNINEGQNVLFTCEISGEPSPE 26667

Query: 752   VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             + W ++   +   + +  + ++ +V++L ++      +G+Y I  KN  G+CS   SLM+
Sbjct: 26668 IEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726

Query: 812   QNSSARALPRGREPA 826
                    LP   EP+
Sbjct: 26727 -------LPLVEEPS 26734



 Score =  122 bits (306), Expect = 3e-27
 Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G  + ++  I G PFP   W ++G+ + K      +  +E    LV+K+     +G Y++
Sbjct: 23654 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23710

Query: 795   LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 848
             +L+N+ G+ +  + + +  S     P G  P   +D+    V       AD GG+D  G 
Sbjct: 23711 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23766

Query: 849   LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 906
             +          W   +    VRG        +++ E   R     Q      L  +  V+
Sbjct: 23767 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23824

Query: 907   TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 963
              KT L+  +    P E +D   +       +   +   +V +   ++ +     K    +
Sbjct: 23825 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 23883

Query: 964   KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 1022
             KT +   +       PD       + ++ A+N    +ET  A + V    P       G 
Sbjct: 23884 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 23939

Query: 1023  LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1070
             L+ +  +K + TL   KP     K             D   K ++KE +K          
Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 23999

Query: 1071  ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
                        +N+    R    T  + K   + G AP  +++++DV    G+   L CQ
Sbjct: 24000 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24058

Query: 1121  VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1180
             +   P   I W   GK L  ++   +S +G   ++++     ED G+Y C+A N+ G+ E
Sbjct: 24059 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24118

Query: 1181  CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1240
              S ++ +   P                                    P  P K       
Sbjct: 24119 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24138

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1299
                 E      G ++ L     G      TW   +K +Q SE++ +EN+E+ + L +   
Sbjct: 24139 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24194

Query: 1300  ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
              R+ H G Y + + N  G+  A +++ + DKPD P G      +  +S  +SW   + DG
Sbjct: 24195 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24254

Query: 1360  GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GS + +Y +E  ++     W+ +++  S T+  + +L  +  Y FRV A N +G S+P +
Sbjct: 24255 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24314

Query: 1418  ESELTTVGEKPEEP 1431
              S +  +    E+P
Sbjct: 24315 VSSVVIIKSPFEKP 24328



 Score =  118 bits (295), Expect = 6e-26
 Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)

Query: 621  TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
            T P  + GL ++ V++G  VT+   +SG P P V W     +I+ S DF    +     L
Sbjct: 895  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954

Query: 681  CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 714
             I+E F ED+G +TC A N AG V T   L VQ                           
Sbjct: 955  MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014

Query: 715  ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
                           P +   P+FI+KP       G SV+  C + G+P P V+W + G 
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074

Query: 760  ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             L   TG+ ++V  N+      LV+       AG+Y I+++N+ GE S   SL L+ +  
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131

Query: 817  RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 875
              L + ++    +      V        + G   PG+  +  +   E+E     + + K 
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186

Query: 876  RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 932
             V  R + E+    QE     F + L K++     KT  E+ L+E   E+M    +    
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242

Query: 933  VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 981
            V+    S  + ++ + + ++   V      S  P+P        +++   +    DF   
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298

Query: 982  -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 1035
             R+ L     LP + G  +A   N K         NA  SG     P  P+G      TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350

Query: 1036 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1095
            +P+   +   +L P   ++    +  A     +         +       +    S+ + 
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407

Query: 1096 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1152
               P F  K       EG+      +V   P     W  +G+ +    T  +++ ++G+ 
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1212
             S+ I  A P D G +  VA+N AG++  S  +TV+                        
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504

Query: 1213 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
                                +  + P  ++  ++  ++ G  +E+  + TG       W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544

Query: 1273 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1327
            K    I   ++  +++E ++  + L I +   +    YT    NK G  + + +VN+ V 
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604

Query: 1328 VDKPDP------PAGTPCASDIRSSSL 1348
              +P+P      P GT  A +I +  L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631



 Score =  115 bits (288), Expect = 4e-25
 Identities = 94/394 (23%), Positives = 168/394 (42%), Gaps = 26/394 (6%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK-ARTRDSG 483
             + E Q +  +  ++G    +V W L G  +   E     Y  +GS     +K A  RD G
Sbjct: 26553 INEGQRLVLKANIAGAT--DVKWVLNGVELTNSEEYR--YGVSGSDQTLTIKQASHRDEG 26608

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
               +C +   +G + C + L + +   +  AP+F S  +   + EGQ+ +  C + G P P
Sbjct: 26609 ILTCISKTKEGIVKCQYDLTLSK--ELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSP 26666

Query: 544   RITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              I W  N  PI  + +        V  L I++A   D G YT  A+N  GQ S +A + V
Sbjct: 26667 EIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726

Query: 601   HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                         LP+   +P+  + L+   D   + GS  + +VQ+S +         + 
Sbjct: 26727 ------------LPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMSASKQEASFSSFSS 26772

Query: 661   NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
             +      +  F     Q    +QE F E + +      N   ++ +     ++    G  
Sbjct: 26773 SSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESSTSKMLKAGIRGIP 26831

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTL 779
             P   + P  ++   G+ + ++CA  G+P P V W   G+ +  ++ G F +   +D+ TL
Sbjct: 26832 PKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTL 26891

Query: 780   VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 813
             ++  VQ    G Y + L N  G  S  V++ +++
Sbjct: 26892 IIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 26925



 Score =  115 bits (287), Expect = 5e-25
 Identities = 164/743 (22%), Positives = 263/743 (35%), Gaps = 170/743 (22%)

Query: 163  FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
            F +++    + EG    F CK++G P P++ W K         R+   E+  M  L+   
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDG------KRIKHGERYQMDFLQ--- 1297

Query: 223  VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE 282
                             G+AS+   + +   +    +F    K           N I   
Sbjct: 1298 ----------------DGRASLRIPVVLPEDEGIYTAFASNIKG----------NAICS- 1330

Query: 283  SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTS 342
             KL  +E AA           G+P +    +P     S++ S   SPR+  ++P+     
Sbjct: 1331 GKL-YVEPAAPL---------GAPTYIPTLEPV----SRIRSL--SPRSVSRSPI----- 1369

Query: 343  SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRR 402
                    R+ P   +P           R  PA   PA      PG   ++       R 
Sbjct: 1370 --------RMSPARMSPA----------RMSPARMSPARM---SPGRRLEETDESQLERL 1408

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
                       P F  KP S +  E QT +F  +V G P PE  WF +G  +        
Sbjct: 1409 YK---------PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKV 1459

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V ++ G+  L ++ A   DSG ++  A N  G+ S S  L VE +   +V P F   LK+
Sbjct: 1460 VIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE-HQVKPMFVEKLKN 1518

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPED 577
              + EG    ++    G P P I WL N     P +Y +   E   G A L I   + +D
Sbjct: 1519 VNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQD 1578

Query: 578  HGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP--------- 617
               YT  A N  G+    C   V V   +   + + ++P          AP         
Sbjct: 1579 SAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRY 1638

Query: 618  -------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNE 662
                          K   P F + L+ L++          +++  G+P   V WLH+G  
Sbjct: 1639 GQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------- 714
            ++ +            SL     +  D+G  TC A N  G   T A L V++        
Sbjct: 1699 LEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEES 1758

Query: 715  ------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCAI 744
                               H+G             +P  +  P  V    G++    C +
Sbjct: 1759 QLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRV 1818

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
             G P P V+W  +G+ L + +  F V + + +  L +   + +  G+ ++  +N  G   
Sbjct: 1819 TGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIE 1876

Query: 805  CQVSLMLQNSS--ARALPRGREP 825
             +V L +Q        L R  EP
Sbjct: 1877 HKVKLEIQQREDFRSVLRRAPEP 1899



 Score =  113 bits (282), Expect = 2e-24
 Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             +K S RK E L     +   AP     +   +V  G      + V   P  EV W HNG 
Sbjct: 25856 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 25915

Query: 662   EIQESE----------------DFHFEQRGTQHSLCI----------------------- 682
             E+QES                 D H +  GT  ++C                        
Sbjct: 25916 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 25975

Query: 683   ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 718
                      + VFPE T T              EA +S  EV++Q   T +      H  
Sbjct: 25976 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26035

Query: 719   TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 752
             +                              ++KPRS+T   G+S   SC   G+P PTV
Sbjct: 26036 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              WLR G+ L     H +V   +   T  +  VQ    G Y ++++N  G+   + +L +Q
Sbjct: 26096 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154

Query: 813   NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 848
              +                        + ++  R + P                 +++   
Sbjct: 26155 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26214

Query: 849   LRPGWPARGQGWLEEEDGEDV--------RGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
             L    P +   +L+ E  +++          VL+ +  T     + +++    Q  +   
Sbjct: 26215 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274

Query: 901   LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 954
                ++    L+E D    + EI  E    + NLQ   +  K++ E+  K+   ++ D + 
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334

Query: 955   --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 983
               S + +K   K P P    P                          P+P    T D ++
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394

Query: 984   VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 1015
             +  GGK KL  + G                            SS+  L  KA++ ++   
Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26454

Query: 1016  -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 1067
              + Q +  + P   A   E +     A  +E +K M  AK  E L   + ASK    EE+
Sbjct: 26455 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26511

Query: 1068  KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
             KK     +     H   T   + SE   T    K     + + EG++L+L+  ++     
Sbjct: 26512 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26569

Query: 1128  TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
              + W LNG  L  ++       GS  +++I++A   D G+  C++K   G  +C   +T+
Sbjct: 26570 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629

Query: 1188  DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1247
                       + E+                SDA                 P  I  P  Q
Sbjct: 26630 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26646

Query: 1248  KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
              +  G++V    +++G       W K    I  S ++ +  S N   L I  A     G 
Sbjct: 26647 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26706

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+  +N  G   A  +L V+   + P+          +SL  S+   S    ++ Q  S
Sbjct: 26707 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26766

Query: 1368  IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1423
                + S++ +   +   +  S + Q +    E    + + +  G S  +Q     S++  
Sbjct: 26767 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26824

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEV 1447
              G +   PK E   SD    E +V
Sbjct: 26825 AGIRGIPPKIEALPSDISIDEGKV 26848



 Score =  112 bits (279), Expect = 4e-24
 Identities = 200/914 (21%), Positives = 315/914 (34%), Gaps = 183/914 (20%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
            +N  I EG    F  ++ GYP P++ W+++G+ I  G R+ +D    G  SL I  V  E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311

Query: 100  DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
            D G YT  A+N  G    + +L VE   A  LG P    TL      R  +P   +R  I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369

Query: 156  WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
                                                     P F  K       EGQ  R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429

Query: 180  FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
            F  K+ GRP P+  W   G   +       V +++G Q L I      D G +T +  N 
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489

Query: 239  SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
            +G++S+S  L+++ ++      FV + K  N          I + S+L+    A  + N 
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538

Query: 298  SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
                      W  NS    P    + ++E  K        + V Q               
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592

Query: 340  -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
              T   + ++    +PEP      ++ P G  R K  A P   P      Q      D+ 
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS--GIPKPEVAWFLEGTP 453
             K   ++           P F+ K  S  +K      F C ++  G P   V W  +G P
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKP 1698

Query: 454  VRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTL----------- 502
            +      + +  + G   L    A +RDSG  +C A+N  G    S TL           
Sbjct: 1699 L-EAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757

Query: 503  -----------QVERLAVMEVAPSFSSVLKD---------------CAVIEGQDFVLQCS 536
                       ++E L  M    + + V  D                 V+EG+    +C 
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817

Query: 537  VRGTPVPRITWLLNGQPIQYAR--STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSC 594
            V G P P++ W LNGQ I+ ++       G+  L I D    D G     AEN  G +  
Sbjct: 1818 VTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEH 1877

Query: 595  SAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               + + +++  R    +L  AP  +P   +   G    +V    +   T +       E
Sbjct: 1878 KVKLEIQQREDFRS---VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETK-----E 1929

Query: 654  VIWLHNGNEI------QESEDFH--FEQRGTQ-----------HSLCIQEVFPEDTGTYT 694
            V+ L     I      +ESE+    F++R  +            S    E + E      
Sbjct: 1930 VVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTK 1989

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWF----------------ISKPRSVTASLGQSV 738
             E  +   E+  +    + E    T P F                  + +S T   G   
Sbjct: 1990 DELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDA 2049

Query: 739  LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 798
                 + G P P   W ++G  + +    +     ++V  LV++ V    +    +   N
Sbjct: 2050 HFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAIN 2109

Query: 799  RVGECSCQVSLMLQ 812
              GE S    L++Q
Sbjct: 2110 IAGETSSHAFLLVQ 2123



 Score =  111 bits (278), Expect = 6e-24
 Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +PP+I+  PE   ++AG+ + +   V G    TC W K   ++  S H+ V  +++ S L
Sbjct: 12401 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12459

Query: 1296  TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1355
              I    ++  G Y+L  EN  G+   ++ + V+D P PP      SDI + + +LSW+  
Sbjct: 12460 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12519

Query: 1356  SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
               DGGS + +Y +E  D +   W   LA+   TS  V  L+P  EY FRVRA N +G SE
Sbjct: 12520 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12579

Query: 1415  PSQESELTTVGE--KPEEPKD 1433
             P    ++        P EPK+
Sbjct: 12580 PLTSPKMVAQFPFGVPSEPKN 12600



 Score =  110 bits (275), Expect = 1e-23
 Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)

Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 567
           AP+F+  L+   V+EG     +  + G PVP ++W  +GQ I  +     + +   G A+
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 568 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
           L I      + G Y+  A N  GQ + +A + V       K+E     AP     P F+Q
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108

Query: 628 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
            L  + V  GSQV + V+V+G P P V +  +G EIQ S DF   Q G  +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168

Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQ 713
           ED+GTY+  A NS G   + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194



 Score =  109 bits (272), Expect = 3e-23
 Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)

Query: 30  TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
           T+AP F  P +++ + EG+TA FE  + G+P P+V+W R+GQ I++        G++ +F
Sbjct: 3   TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58

Query: 90  S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
           S     L I AV + + G+Y+ +ATNGSG    T EL V+   A                
Sbjct: 59  SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102

Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
                          PP F  +L  + V++G   R   ++TG P P V + +    +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147

Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
               +S++  +  L I     +D G Y+    N  G+A+ +AEL +QG            
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207

Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
           + +A  S  R+T+     +   +  ++ + E  +D   AA +     +P R   PP   +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263

Query: 312 SQPQPP 317
             P PP
Sbjct: 264 RSPTPP 269



 Score =  109 bits (272), Expect = 3e-23
 Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)

Query: 1249 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
            V+AG  +EL   VTG      TW K    +++ + + +EN    S +TI+ +++   G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264

Query: 1309 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             +   N  G   A V + V+DKP PPA     +D+ + S  L+W     DGGS + +Y +
Sbjct: 7265 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7323

Query: 1369 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1426
            E   + ++ W +L +T + T+F    L+P+ EY FRV A N+YG  EP Q S +T   + 
Sbjct: 7324 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7383

Query: 1427 KPEEPKDEVEVSD 1439
             P  P   +E SD
Sbjct: 7384 DPPGPPTRLEPSD 7396



 Score =  105 bits (262), Expect = 4e-22
 Identities = 101/411 (24%), Positives = 157/411 (38%), Gaps = 48/411 (11%)

Query: 415  KFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            +F    +  +V E +   F CEVS  P   V W  +   ++  +  I++ ++   H L +
Sbjct: 3013 EFRKHIKDIKVLEKKRAMFECEVSE-PDITVQWMKDDQELQITD-RIKIQKEKYVHRLLI 3070

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
               R  D+G Y+  A            +   +L V        S+ K+  VIE Q  V++
Sbjct: 3071 PSTRMSDAGKYTVVAGG---------NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVE 3121

Query: 535  CSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
              V    V    W  +G  I +      +   E  +  + I +    D G YT +A    
Sbjct: 3122 FEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGR-- 3178

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
                            +R S  L   AP  P     LQ L  + V  G        +SG 
Sbjct: 3179 ----------------NRSSVTLYVNAPEPPQV---LQELQPVTVQSGKPARFCAVISGR 3219

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P P++ W      +       F   G +++L + E FPED   YTCEA N  G   T A 
Sbjct: 3220 PQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSAS 3279

Query: 710  LTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            L+V+ P     D   P +    I+  +    S GQ     C ++G       + +D K  
Sbjct: 3280 LSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKK-- 3337

Query: 762  CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             K +  F + Q ED + L + +  P   G Y  +  N VG+ S   +L L+
Sbjct: 3338 IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLE 3388



 Score =  104 bits (260), Expect = 7e-22
 Identities = 104/484 (21%), Positives = 179/484 (36%), Gaps = 53/484 (10%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            PP+   +L  V V+ G+  RF   I+GRPQP+++W K    L    +           L 
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            +     +D  VYTC   N  G A+ SA LS++         V E  + + ++      +I
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVSPDQEMPVYPPAII 3302

Query: 280  SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVL 338
            +      + E       C          W +  +  +P R  ++   +D+ +        
Sbjct: 3303 TPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYP 3362

Query: 339  QKTSSSITLQAARVQPEPRAPGLGVLSPSG-------EERKRPAPPRPATF-PTRQPGLG 390
            +   +   + +  V        L + +P         +E +       ++F    + GL 
Sbjct: 3363 EDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLH 3422

Query: 391  SQDVVSKAANRRIPM-----------EGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSG 439
            S ++     N  + +           + +++   P F  +  + ++           V G
Sbjct: 3423 SAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIG 3482

Query: 440  IPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCS 499
            IPKP++ WF  G  +        V+ D   H L +L  +  D G Y+C ASN  G+  CS
Sbjct: 3483 IPKPKIQWFFNGVLLTPSADYKFVF-DGDDHSLIILFTKLEDEGEYTCMASNDYGKTICS 3541

Query: 500  WTLQVE-----------RLAVME--------VAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
              L++              AV +          P F   LK     +G   + + +V G 
Sbjct: 3542 AYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGE 3601

Query: 541  PVPRITWLLNGQ----PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
            P P +TW    +     + Y       G     + D   ED G Y C AEN LG+ +C+A
Sbjct: 3602 PAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAA 3661

Query: 597  WVTV 600
             + V
Sbjct: 3662 ELLV 3665



 Score =  102 bits (253), Expect = 5e-21
 Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             +++ E  K RAG SV+L   ++G    T  W K  K++Q +  + VEN+ + + + I  A
Sbjct: 20379 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20438

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              + + GCY L + N +GS  A + + ++DKP PP G      + +  +TL W   + DGG
Sbjct: 20439 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20498

Query: 1361  SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             + +  Y +E  +++   W    + L  C  T+  +   +  +EY FRVRA+N YG  EP 
Sbjct: 20499 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20555

Query: 1417  QESEL 1421
             +   +
Sbjct: 20556 ESDSV 20560



 Score =  101 bits (252), Expect = 6e-21
 Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)

Query: 1236  MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
             +PP +   ++  E   V+AG +V     + G    T  W     +I+  EH  VE     
Sbjct: 11009 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11068

Query: 1293  SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1352
             S LTI    +   G Y + V N  GS+   V+LTV+D P PP G     D+    +T+SW
Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11128

Query: 1353  YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1411
                  DGGS V +Y +E  D+   TW  +++  S T   +  L    EY FRVRA N  G
Sbjct: 11129 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11188

Query: 1412  TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1469
                P  +S  T    K  P  P  +  V+D  E    V +     +    ++ +Y +E R
Sbjct: 11189 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11246

Query: 1470  LGSGKFGQV 1478
               +GK+ +V
Sbjct: 11247 EVTGKWVRV 11255



 Score =  101 bits (252), Expect = 6e-21
 Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+ +M P+   + +   V AGES ++   + G    T  W+K  +++  +  +++++++
Sbjct: 16043 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16099

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L++  A +   G Y L  +N  G R   VN+ V+D+P PP G    S + +   TL
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16159

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGGS + +Y +E  +++   W  + A  ++ S  V  LL  +EY FR+ A+N 
Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16219

Query: 1410  YGTSEPSQESELTTVGE--KPEEPK 1432
             YG  EP +   +        P+ PK
Sbjct: 16220 YGVGEPLESEPVVAKNPFVVPDAPK 16244



 Score =  101 bits (251), Expect = 8e-21
 Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)

Query: 1243  FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
             F +   VRAG S+ LF    G    T  W K    +  S    +  +++ S LT+    +
Sbjct: 21866 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 21923

Query: 1303  EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1362
                G YTL VEN  GS+     + V+D P PP G     D+   S TL W     DGG+ 
Sbjct: 21924 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 21982

Query: 1363  VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             +  Y +E  +++ ++W+ ++  C    F V DL     Y FRV A+N YG  EP +  E 
Sbjct: 21983 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22042

Query: 1422  TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1471
                 E+P  P+  D V+ S         +P+ D         +   QK SDF+ +E    
Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22101

Query: 1472  SGKFGQVFRLVEK 1484
                   V RLVEK
Sbjct: 22102 KQLTFTVERLVEK 22114



 Score =  100 bits (250), Expect = 1e-20
 Identities = 133/588 (22%), Positives = 220/588 (37%), Gaps = 101/588 (17%)

Query: 63   QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
            +V W+   + + S  +F  L D   + T++LVI  V+ ED +G+Y CEA N SG    + 
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4327

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
            +LTV    A     PV+ +                           K+  + V  G + +
Sbjct: 4328 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4355

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F+C+I   P  +  W K    +  S + S+     +  LEI      D G YTC   N  
Sbjct: 4356 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415

Query: 240  GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
            G  S +A L  ++ G +   R  + E K    + ++EV   +V+ K  + +  +   K  
Sbjct: 4416 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4472

Query: 295  KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
            +    P     PP      P+P  E ++ +     R  P+   + +   +I L A   +P
Sbjct: 4473 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4526

Query: 355  EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
            +P A    +  P  E    P    P T P       ++    +AA  + P++G       
Sbjct: 4527 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4585

Query: 415  KFES-----KPQSQEVKENQTVKFRCEVSGIP---------------------------- 441
              E+     +P S   K      F  ++  +P                            
Sbjct: 4586 PIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLV 4645

Query: 442  KPEVA---WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
             P  A   W  +G+ + R+        D     L ++  +  D+G Y+C       + + 
Sbjct: 4646 SPSTAITTWMKDGSNI-RESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTS 4704

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
            +  L VE L V  V     ++ ++  V++GQ   L C +       + W  +G+ +    
Sbjct: 4705 TAKLVVEELPVRFV----KTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKP 4758

Query: 559  STCEAGV----AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
                 GV      L I DA   D GTYT   ENA   + CS+ V V E
Sbjct: 4759 GRIVPGVIGLMRALTINDADDTDAGTYTVTVENA-NNLECSSCVKVVE 4805



 Score =  100 bits (250), Expect = 1e-20
 Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)

Query: 1241  IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1300
             ++F +   ++AGE+  L   V+G  P T  W K  K+++ +  ++++ ++  + L    +
Sbjct: 14968 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15027

Query: 1301  RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1360
              +   G YTL   N  G  +   N+ V+D+P PP G    +++ S    LSW+    DGG
Sbjct: 15028 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15087

Query: 1361  SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             + +  Y ++  +++   W  +A+  + T   V  LL  +EY FRV A+N YG  EP +  
Sbjct: 15088 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15147

Query: 1420  ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1471
              +  V     P+ PK+ EV     D        P+ D  +  IN        Y +E R  
Sbjct: 15148 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15197

Query: 1472  SGKFGQVFRLVEKKT 1486
               K GQ +    KKT
Sbjct: 15198 -DKAGQRWIKCNKKT 15211



 Score =  100 bits (249), Expect = 1e-20
 Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V AGE +++     G      TW K    ++++  +  E++EN S LTI  A +E  G Y
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + + N  G     +N+ V+DKP PP G     ++ + S+TLSW    YDGGS++ +Y +
Sbjct: 15722 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15781

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             E  D++  TW+ + AT   T+     L    EY+FR+ A N YG S
Sbjct: 15782 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15827



 Score =  100 bits (248), Expect = 2e-20
 Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)

Query: 512  VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 567
            V   F S +K+  ++EG      C + G P+P+I W  +G+ I    +Y     + G A 
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 623
            L I   LPED G YT  A N  G   CS  + V          Y   L PV+  +  +P 
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362

Query: 624  -------------------------------------------------IFLQGLSDLKV 634
                                                             +F+      K 
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            ++G      ++V G P PE  W H+G +I    +     ++ GTQ SL I    P D+G 
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            +T  A N AG      +LTV+      +P F+ K ++V    G  + +     G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541

Query: 753  HWLRD 757
             WL++
Sbjct: 1542 VWLKN 1546



 Score =  100 bits (248), Expect = 2e-20
 Identities = 191/884 (21%), Positives = 315/884 (35%), Gaps = 165/884 (18%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+V   A++  S  +L     +V  +PL     FI P  ++ + E   AKFE  V   P+
Sbjct: 5321 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5371

Query: 62   PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
                W +  Q IT   RF L+  G + +  +   A  +E +  +  E  + SG       
Sbjct: 5372 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5430

Query: 115  --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
                    + VT +      F  +L    +                       KT    F
Sbjct: 5431 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5490

Query: 145  SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
               +++    I  E                P F  KL      E       C+I+    P
Sbjct: 5491 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5550

Query: 191  QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL-- 248
             V W K    ++PS    +      ++L +    + D+G YTC    G+ K S   ++  
Sbjct: 5551 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDC--GTDKTSGKLDIED 5607

Query: 249  ----------SIQGLDSANRSFVRETKATNSDVR-----------KEVTNVISKESKLDS 287
                      S++ +++    F  ET+ +  D+            +     I +E K+ S
Sbjct: 5608 REIKLVRPLHSVEVMETETARF--ETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHS 5665

Query: 288  LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK------LESCKDSPRTAPQTPVLQKT 341
            L       NC   Q GG    AAN +       K      L   KD   TA +T      
Sbjct: 5666 LVL----HNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCE 5721

Query: 342  SS------SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
             S         L+  +++P  +      + P  E +      R      +    G   + 
Sbjct: 5722 LSYEDIPVEWYLKGKKLEPSDK------VVPRSEGKVHTLTLRDV----KLEDAGEVQLT 5771

Query: 396  SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
            +K       +  +      +F    + Q V+E  T    CEVS     +V WF  GT + 
Sbjct: 5772 AKDFKTHANLFVKEPPV--EFTKPLEDQTVEEGATAVLECEVSR-ENAKVKWFKNGTEIL 5828

Query: 456  RQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPS 515
            + +   E+  D     L +      D  TY+C A + +   SC+       L V+     
Sbjct: 5829 KSK-KYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFK--TSCN-------LNVVPPHVE 5878

Query: 516  FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 572
            F   L D  V E +    +C +      ++ W  +G  I+  +      +  V  L I  
Sbjct: 5879 FLRPLTDLQVREKEMARFECELSRENA-KVKWFKDGAEIKKGKKYDIISKGAVRILVINK 5937

Query: 573  ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 632
             L +D   Y+C    A      S  +TV E+++                  +F + L+++
Sbjct: 5938 CLLDDEAEYSCEVRTA----RTSGMLTVLEEEA------------------VFTKNLANI 5975

Query: 633  KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 692
            +V +   + +  +VS  P  EVIW     EI E+  +     G +  L IQ    ED G 
Sbjct: 5976 EVSETDTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGN 6034

Query: 693  YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 752
            Y C   +S    RT   + V E        FISKP+++    G+     C+I+ + FP V
Sbjct: 6035 YNCRLPSS----RTDGKVKVHE----LAAEFISKPQNLEILEGEKAEFVCSISKESFP-V 6085

Query: 753  HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILL 796
             W RD K L +    ++V+ +     LV+K       G Y +++
Sbjct: 6086 QWKRDDKTL-ESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV 6128



 Score =  100 bits (248), Expect = 2e-20
 Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)

Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1288
            MPP I    E  +V  G +V +  K+ G    T TW K        ++ +    H+    
Sbjct: 9619 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9677

Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1348
             ++   L I  +R+   G YT+   N LG+   ++ L V+ +P PP G      + +  +
Sbjct: 9678 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9737

Query: 1349 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1407
            TLSW+    DGGS + +Y IE  ++  KTW  +++  +  ++ +  LL  HEY FR+ A 
Sbjct: 9738 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9797

Query: 1408 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
            N YG  EP        +  +PE  ++   V  + D      V   ++T+N E+   D
Sbjct: 9798 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9846



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 106/466 (22%), Positives = 176/466 (37%), Gaps = 63/466 (13%)

Query: 289  EAAAKSKNCSSPQRGGSPPWAANSQPQP-----PRESKLESCKDSPRTAPQTPVLQKTSS 343
            E  + +K    PQR  S P       +P     P E+ +++             ++KT+ 
Sbjct: 693  ERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTTDQKGMHISSQ--IKKTTD 750

Query: 344  SITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
              T +   V   PR       SP     K   P             G +  ++ +A   +
Sbjct: 751  LTTERLVHVDKRPRTA-----SPHFTVSKISVPKTEH---------GYEASIAGSAIATL 796

Query: 404  PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEV 463
              E    S+  K     ++  VK ++T   R      P P+   F +     + E  +EV
Sbjct: 797  QKELSATSSAQKITKSVKAPTVKPSET---RVRAEPTPLPQFP-FADTPDTYKSEAGVEV 852

Query: 464  YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
             ++ G   + +     R+          A+   +      VE   +    P+  S LK+ 
Sbjct: 853  KKEVG---VSITGTTVREERFEVLHGREAKVTETARVPAPVE---IPVTPPTLVSGLKNV 906

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGT 580
             VIEG+   L+C + G P P +TW      I+ +   + T ++G+A L I++A  ED G 
Sbjct: 907  TVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGR 966

Query: 581  YTCLAENALGQVSCSAWVTVH-----EKKSSRKSEYLLP--------------------- 614
            +TC A N  G VS S ++ V      EK+++  +E                         
Sbjct: 967  FTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEE 1026

Query: 615  -VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HF 671
               P +P AP F+      K+++G  V    QV GNP P V W  +G  +     +   +
Sbjct: 1027 QAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSY 1086

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             ++  +  L I   F +D G YT    N  GE    A L  +  ++
Sbjct: 1087 NKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYE 1132



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P+ +M P+   F +   V AGE+  L   V G    T  W++  K+I+ES   +++N++ 
Sbjct: 17126 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1351
              + L +  A +   G Y L   N  GS+   VN+ V+D+P PP G    + + S   +L+
Sbjct: 17183 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17242

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1410
             W     DGGS +  Y +E  +++   W  +A+   + S  V  LL  +EY FR+ A+N Y
Sbjct: 17243 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17302

Query: 1411  GTSEPSQES 1419
             G  EP + +
Sbjct: 17303 GVGEPLESA 17311



 Score = 97.8 bits (242), Expect = 9e-20
 Identities = 80/318 (25%), Positives = 131/318 (41%), Gaps = 41/318 (12%)

Query: 426   KENQTVKFRCEVSGIPKP-EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +E   VK+ C++    +  +V W+     +   E     YED G   L +      D GT
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYED-GVAILYVKDITKLDDGT 25141

Query: 485   YSCTASNAQGQLS-----------------CSWTLQ-----VERLAVMEVAPSFSSVLKD 522
             Y C   N  G+ S                 C  T++      + + ++E  P F+  L +
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYN 25201

Query: 523   CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS------TCEAGVAELHIQDALPE 576
                  G++     ++   P P +TW  +GQ I+   +        + G+ +L I     +
Sbjct: 25202 KTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTD 25261

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
             D   YT +A N  G+ SC A +TV           L P        P+F + L++ +  +
Sbjct: 25262 DDAEYTVVARNKYGEDSCKAKLTV----------TLHPPPTDSTLRPMFKRLLANAECQE 25311

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 695
             G  V   ++VSG PPP + W  +G  +    +      G   ++L I++  PEDTG Y  
Sbjct: 25312 GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRV 25371

Query: 696   EAWNSAGEVRTQAVLTVQ 713
              A N+AG    QA L V+
Sbjct: 25372 TATNTAGSTSCQAHLQVE 25389



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G +V L     G    + +W+K    ++ESE ++   +EN   L+I  A++EH G Y
Sbjct: 21078 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21137

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T++++N +      + +  +  P  P G     +I++ S+ LSW     +GG  +  YSI
Sbjct: 21138 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21197

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  +++   WK + ++   T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21198 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21245



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 134/595 (22%), Positives = 226/595 (37%), Gaps = 60/595 (10%)

Query: 161   PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
             P+   ++    V  GQ  RF   +  +P  +V W    V LQ S+++  +  +G+  LEI
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV-- 278
                + DD G Y  +  N  G+AS  A L + G D    +  R  +     V  E+T    
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 25996

Query: 279   --ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
               +S   K   +EA++  +   S     +    + S  +    ++++S     ++  +  
Sbjct: 25997 YAVSSFKKTSEMEASSSVREVKSQM---TETRESLSSYEHSASAEMKSAALEEKSLEEKS 26053

Query: 337   VLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVS 396
               +K  +++   AAR+  +PR+    +    GE  +          PT    L    V+S
Sbjct: 26054 TTRKIKTTL---AARILTKPRS----MTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLS 26105

Query: 397   KAANRRIPMEGQRDSAFPKFESKPQSQE-----VKENQTVKFRCEVS-GIPKPEVAWFLE 450
              +A  ++     + +   +  S   S E     V EN   K   E +  I K  V     
Sbjct: 26106 TSARHQVTTTKYKSTF--EISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAV 26163

Query: 451   GTPVRRQEGSIEVYEDAGSHYLCLLKARTR-DSGTYSCTASNAQGQLSCSWTLQVERLAV 509
              +P R +     V           +K+  R  S   S   + +  +   + T +V+ L V
Sbjct: 26164 TSPPRVKSPEPRVKSPEA------VKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEA 563
                 P  +  LK  A    +   L C V  + +    +TW  +G+ ++    +       
Sbjct: 26218 -SAPPKITQFLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274

Query: 564   GVAELHIQDALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKS 609
             G  EL I +    D G Y C      G      Q    A+ ++HEK        KS +K+
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334

Query: 610   EYLLPVAPSKPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
                     ++P AP       + + GL D  V   S     V+ +G P P  IW  +G  
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394

Query: 663   IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
             I +   +   +      L I +    D+G YTC   NSAG V +   LT++   D
Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG +V L   V G    T +W K    ++ +E +K+    N   L + +  ++  G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN  GS+ A + L V+DKP PPA     + + S    LSW     DGGS + +Y +
Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 12928

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             +  +++   W ++ AT   TS +V+ L+  HEY+FR+ A N YG  +P
Sbjct: 12929 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 12976



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 114/507 (22%), Positives = 189/507 (37%), Gaps = 105/507 (20%)

Query: 5     KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
             K +    I+KTS + +  R  +    E  AF      + I EG     +  + G  +  V
Sbjct: 26521 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26571

Query: 65    TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              W  NG  +T+   +    G+ G+  +L I      D G  TC +    G  +   +LT+
Sbjct: 26572 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629

Query: 124   EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
                          SK L D   APA  ++P                  + EGQ   F+C+
Sbjct: 26630 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26659

Query: 184   ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
             I+G P P++ W K N+P+  S+ VS+S    +  LEI   +  D G YT    N  G+ S
Sbjct: 26660 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26719

Query: 244   MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
              +A L +  L                 V +    V+ + S   SL+   +++S   S+ +
Sbjct: 26720 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26762

Query: 302   RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
             +  S    ++S      E K  S      ++ Q   ++ +SSS                +
Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26807

Query: 362   GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
             G+ + +  E                    S   + KA  R IP         PK E+ P 
Sbjct: 26808 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26839

Query: 422   SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYLCLLKARTR 480
                + E + +   C  +G P PEV W   G  +  QE G   +        L ++  + +
Sbjct: 26840 DISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQ 26899

Query: 481   DSGTYSCTASNAQGQLSCSWTLQVERL 507
             D G Y+ +  N  G  S +  + +  +
Sbjct: 26900 DGGLYTLSLGNEFGSDSATVNIHIRSI 26926



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)

Query: 1228  PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P T      PP + + F +   +R GE+  L G+ +G      +W K    + E +   +
Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1346
             + +     L  + A++   G Y ++VEN  GSR+    + VVD+P PP G     ++   
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1405
              + +SW     DGGS + +Y IE  +     W  + +  + T+  V  LL   +Y FR+ 
Sbjct: 10431 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490

Query: 1406  AINVYGTSEPSQESELTT-----VGEKPEEP 1431
             A N+YG S+P     +       V + P++P
Sbjct: 10491 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10521



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            +G    + + +    K P      P I     D  V  GE + +          T +W K
Sbjct: 7869 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
              K+++ S+ + ++N    + L +  + +   G YT+ +ENKLGS  A +N+ V+  P P
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 7985

Query: 1334 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1392
                  ASDI  SS  L+W    +DGG+ +  Y +E  ++  +T+  + +  +  S+ V+
Sbjct: 7986 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8044

Query: 1393 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1449
            DL+P+ EY FRV+A+N  G  E   E +   + + P++P D   +VEV +   +   + +
Sbjct: 8045 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8103

Query: 1450 RTVTINTEQKVSDFYDIEERLGSGK 1474
            +    +   K+  +  I E++  G+
Sbjct: 8104 KPPLYDGGSKIMGY--IIEKIAKGE 8126



 Score = 95.9 bits (237), Expect = 3e-19
 Identities = 85/332 (25%), Positives = 138/332 (41%), Gaps = 31/332 (9%)

Query: 506   RLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG-TPVPRITWLLNGQPIQYARS---TC 561
             ++A +E+ P    ++      EG      C +       ++TW    + ++ +     T 
Sbjct: 25064 KVASIEIGPVSGQIMHAVGE-EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITY 25122

Query: 562   EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE-------------KKSSRK 608
             E GVA L+++D    D GTY C   N  G+ S  A + V               KK  R+
Sbjct: 25123 EDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRR 25182

Query: 609   SEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
             ++ + L   P + T P++     +     G  V   V ++ +P P V W  +G +I+  +
Sbjct: 25183 TDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGD 25237

Query: 668   D---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGT-Q 720
             +   + FE     + L I  V  +D   YT  A N  GE   +A LTV     P D T +
Sbjct: 25238 NDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLR 25297

Query: 721   PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
             P F     +     GQSV     ++G P PT+ W +DG+ L        + +  D + L 
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357

Query: 781   LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             ++   P   G Y +   N  G  SCQ  L ++
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 95.5 bits (236), Expect = 4e-19
 Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)

Query: 1249  VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             ++AG+++ L    + G      +W K  K I+ S+  ++ ++   S LTI  A ++  G 
Sbjct: 13893 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 13952

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1367
             YT+   N  G++   V +TV+D P PP G    S++ +   TL+W     DGGS ++SY 
Sbjct: 13953 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14011

Query: 1368  IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E  +++   W    +++ +CR  +     L+  +EY FRV A+N YG  EP Q   +  
Sbjct: 14012 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14068

Query: 1424  VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             V    P  P ++ EVS+       V   T T++ ++ V D
Sbjct: 14069 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14101



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S+ +F  + G      TW K    I       +EN+E+ + L I    +   G +
Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14348

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + +EN  G +   VN+ V+D P P       +DI   S+TL W     DGGS + +Y +
Sbjct: 14349 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14407

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++    T C   ++ V  L    EY FRV A N YG  EP++ +E     E 
Sbjct: 14408 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14467

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1478
             P  P D + + D  +    + +     +   K++ +    +R GS ++  +
Sbjct: 14468 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14517



 Score = 94.7 bits (234), Expect = 7e-19
 Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PP+  M    ++F +   V+AGE +++   + G      +W K   +I+E    ++ +++
Sbjct: 19289 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19345

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
             N + LT+    +   G Y L ++N  G+R   VN  V+DKP PPAG    + + +   +L
Sbjct: 19346 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19405

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             SW     DGG+ +  Y +E  ++++  W       + TS  V  LL  +EY FRV  +N 
Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19465

Query: 1410  YGTSEP 1415
             YG  EP
Sbjct: 19466 YGVGEP 19471



 Score = 94.4 bits (233), Expect = 9e-19
 Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ L   V+G  P   TW K  + I  +    ++ +E+ S L +    +   G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23018

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+  EN+ G + A V + V D P P        ++   S+T++W   + DGG+ V +Y +
Sbjct: 23019 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23077

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++A + +K + T C  T + +  L+    Y FRV   N+YG  EP + S+   V E 
Sbjct: 23078 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23137

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             P  P  ++EV D       V   TVT+  E+ + D
Sbjct: 23138 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23164



 Score = 94.0 bits (232), Expect = 1e-18
 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+A E +++     G    T  W K  + ++E+  + V +S+  + L+I  A +E  G Y
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L V N  GS    + + V+D+P PP G     ++   S+T+SW    YDGG  + +Y +
Sbjct: 18969 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19027

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++ + TW  ++     TS  +  L    EY+FRV A N YG S  S+ S    V E 
Sbjct: 19028 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19085

Query: 1428  PEEP 1431
             P  P
Sbjct: 19086 PFSP 19089



 Score = 93.2 bits (230), Expect = 2e-18
 Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)

Query: 1250 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1301
            +AG  + +   + G      +W    K +K +++  H      ++E +EN S + I   +
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            + H G Y++  +NK G + A   + V+D P PP      SDI   S  LSW     DGG 
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9444

Query: 1362 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             ++ Y IE      K W ++   C ST+F V DLL + +Y FRVRA N +G   P +  +
Sbjct: 9445 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9504

Query: 1421 LTTVGEK--PEEPKDEVEV 1437
             TT  +   P +P  ++++
Sbjct: 9505 RTTARDPIYPPDPPIKLKI 9523



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 146/682 (21%), Positives = 239/682 (35%), Gaps = 63/682 (9%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            + P F     +L +K    A FE R+   G P   V W  +G+P+ +  R  +     G 
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
             SL     +  D G  TC ATN  G    +  L V  E S  ++   P   K L      
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773

Query: 147  PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
              +    ++ G       +  P        V V EG+  RF C++TG PQP+V W     
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             ++ S R  V   +G+  L+I      D G       N  G      +L IQ  +   RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891

Query: 260  FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
             +R       +        +  E  K+D      ++K     +R          +     
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951

Query: 319  ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
             SK +   +       T V  K+          ++             + EE+K  A   
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              T PT +P              +I +    ++  PK   + QSQ V +     FR  V 
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVRVV 2056

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
            G P PE  W+  G  + R +     + +     L +      DS +    A N  G+ S 
Sbjct: 2057 GKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSS 2116

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA- 557
               L V+   ++    +F+  L+D    E             P  ++ W  +G  +    
Sbjct: 2117 HAFLLVQAKQLI----TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGD 2172

Query: 558  --RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
              R   +  V  L I      D   Y+C              V V ++     ++ ++  
Sbjct: 2173 KYRMHSDRKVHFLSILTIDTSDAEDYSC--------------VLVEDENVKTTAKLIVEG 2218

Query: 616  APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI---WLHNGNEIQESEDFHFE 672
            A  +     F++ L D++V +     +   VS    PE I   W HN  E++ +  +   
Sbjct: 2219 AVVE-----FVKELQDIEVPESYSGELECIVS----PENIEGKWYHNDVELKSNGKYTIT 2269

Query: 673  QRGTQHSLCIQEVFPEDTGTYT 694
             R  + +L +++V  ED G Y+
Sbjct: 2270 SRRGRQNLTVKDVTKEDQGEYS 2291



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1290
             P A++ P+   + +   V AGE+  L   + G       W K  K+++E+   M+++++ 
Sbjct: 18208 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18264

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               + L +    +   G Y L + N  G++   + + V+D+P PP G    + + +    L
Sbjct: 18265 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18324

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y IE  +++  +W +++T  ++ ++ V  LLP +EY FRV A+N 
Sbjct: 18325 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18384

Query: 1410  YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1438
             YG  EP +   +T     KP  P    EVS
Sbjct: 18385 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18414



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
             T +  TV+      T   + MP + I  P      AG  VEL   + G  P   +W    
Sbjct: 23226 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23279

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
              +++ESE + VE     +KLTI        G YTL ++N  G+    + + ++DKP PP 
Sbjct: 23280 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23339

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1394
             G     +I ++S+T+SW     DGG+ +  Y +E  D+    W  ++ +   ++F    L
Sbjct: 23340 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23399

Query: 1395  LPDHEYKFRVRAINVYG 1411
                +EY FRV A N +G
Sbjct: 23400 TEGNEYVFRVAATNRFG 23416



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)

Query: 27   MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
            +P+T  P  +   +N+ + EG +   E  + GYP P VTW+R    I S   F +     
Sbjct: 892  IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
            G   L+I     ED G++TC A N +G    +  L V+ S   +     V++   T   R
Sbjct: 950  GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009

Query: 144  F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
            F  S   V T  S+  E         P F TK     + EG    F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069

Query: 195  LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             K  VPL    R  VS +++ G   L I     DD G YT +V N  G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AGE V++     G  P T TW K  K +       +EN+++ S LTI    +   G Y 
Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20846

Query: 1310  LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             L +EN +G  + + V++ V+D P           +   ++TL W     DGGS + +Y I
Sbjct: 20847 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  D+  +TW  ++  C STSF + DL     + FRV A N  G  EP + +E     E 
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 20965

Query: 1428  PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1474
             P  P  ++ + D  +    + +     +    ++++  + ER G G+
Sbjct: 20966 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21009



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+ G+ +++   ++G    T TW K    ++++  + V +S + + L+I    ++  G Y
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              + V N +G + A + +  +DKPDPP G     D+ + S+TLSW    Y GG  + +Y +
Sbjct: 16804 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16863

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             +  D+    W  + AT   T+  V  L    EY+FR+ A N YG S
Sbjct: 16864 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)

Query: 1248 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1301
            KV+AGE V +   VTG       W K    I++          +V  SE  ++L+I  A 
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            +E  G YT+   N+LGS    V++ V D+P PP      +DI++ S  L+W     +GGS
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9030

Query: 1362 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1418
             +  Y I+  D++ K   W+E+  T     + +  L+P+ +Y+FRVRA+N YG S+  + 
Sbjct: 9031 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9090

Query: 1419 SEL 1421
             ++
Sbjct: 9091 DKV 9093



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)

Query: 1226  PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
             P P        PP++I       +Q ++ G+++ L   + G      TW K  +      
Sbjct: 10707 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10766

Query: 1283  HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
              + V  +  GSKL I  A  E  G Y+L VEN  GS+   V + V+DKP PP      S+
Sbjct: 10767 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10823

Query: 1343  IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1401
             IR  S  L+W     DGGS + +Y +E  D A+  W  L AT +  S   + L   ++Y 
Sbjct: 10824 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 10883

Query: 1402  FRVRAINVYG 1411
             FRV A N YG
Sbjct: 10884 FRVAAENQYG 10893



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)

Query: 1232  PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
             PKA    +PP+I    + +KV   RA  ++ LF  + G       W   R   +  +   
Sbjct: 15352 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15409

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             +E++ + + L +    +   G Y L VEN  GS+ A VN+ V+D P PP       ++  
Sbjct: 15410 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15468

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S+TL+W     DGGS +++Y +E  +S  K +  +AT C  TS+ V  L     Y FRV
Sbjct: 15469 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15528

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A N YG   P++ +E     E+P  P
Sbjct: 15529 LAENEYGIGLPAETAESVKASERPLPP 15555



 Score = 90.5 bits (223), Expect = 1e-17
 Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)

Query: 1249  VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1307
             V AG  + +   V+G  P T TW M  R   QE+    +E +   S + I   ++ H G 
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10095

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
             Y+LL +N+ G R+  + + V+D P  P GTP  A ++ + S  L+W+    DGGS + +Y
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10154

Query: 1367  SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1425
              IE  +S  + W  +  T    +  VQ L+    Y FR+ A N  G     + SE   + 
Sbjct: 10155 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214

Query: 1426  EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1475
             E    PE P+D +EV        EV   TVT+       D       Y +E RL G+ KF
Sbjct: 10215 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10266

Query: 1476  GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1524
                     K T      + +     KE +     +S +N +   K   C
Sbjct: 10267 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10308



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             +RAG S+ LF  + G       W K   +I+++  + V +S   + L +    +   G Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16514

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL +EN  G++ A V + V+D P PP      ++I   S++++W     DGGS +++Y +
Sbjct: 16515 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16573

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  ++  K++  + T C   S+ +  L     Y FRV A N YG   P+Q ++   V E 
Sbjct: 16574 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16633

Query: 1428  PEEP 1431
             P+ P
Sbjct: 16634 PQPP 16637



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)

Query: 1228  PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1278
             P   P      +++++P+   D++ + G  V   G +  T PI       C W K  + I
Sbjct: 23621 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23680

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
               S+   +  SE  ++L I  A +   G Y L++ENK G +   + + V+  P+ P G  
Sbjct: 23681 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23738

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1397
                DI+  S+ +SW   + DGG+ +  Y +E  +     W  + +  R TS  V+ L  +
Sbjct: 23739 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23798

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1454
              EY FRV A N +G S+P +  E  T       PE P +  EV D  +    + +     
Sbjct: 23799 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23858

Query: 1455  NTEQKVSDFY 1464
             +   +V+ +Y
Sbjct: 23859 DGGSRVTGYY 23868



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)

Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 679
           AP F Q L  + V++GS  T    +SG P PEV W  +G  I  S            +  
Sbjct: 5   APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
           L I  V   ++G Y+ +A N +G+  + A L V+   +   P F+ + +S+T   G  V 
Sbjct: 65  LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122

Query: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
           +   + G P P V + RDG  + + +  F++ Q  D+++L++ +  P  +G Y +   N 
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 800 VGECSCQVSLMLQ 812
           VG  +    L++Q
Sbjct: 182 VGRATSTAELLVQ 194



 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 94/390 (24%), Positives = 154/390 (39%), Gaps = 52/390 (13%)

Query: 408  QRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDA 467
            Q++   P     P+   V E +T +FRC V+G P+P+V W+L G  +R+ +     Y+  
Sbjct: 1789 QKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYD-- 1846

Query: 468  GSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE 527
            G HYL ++  ++ D+G    TA N +G +     L++++         F SVL+      
Sbjct: 1847 GIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQ------REDFRSVLRRAPEPR 1900

Query: 528  GQDFV-----LQCSVRGTPVP-------RITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
             +  V     LQ  V+    P        +  L   + I + +   E+   EL  +    
Sbjct: 1901 PEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEES--EELRSKFKRR 1958

Query: 576  EDHGTYTCLA-------------ENALGQVSCSA--WVT--VHEKKSSRKSEYLLPVAPS 618
             + G Y  +              E  L +       W      E+K +   E  + +   
Sbjct: 1959 TEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTF 2018

Query: 619  KPT---------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            KP          AP   + +    V  GS     V+V G P PE  W  NG +I+ S+  
Sbjct: 2019 KPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRI 2078

Query: 670  H-FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 728
            + +        L I++V  ED+ +   +A N AGE  + A L VQ     T   F  + +
Sbjct: 2079 YWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLIT---FTQELQ 2135

Query: 729  SVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
             V A    ++        +PF  V W +DG
Sbjct: 2136 DVVAKEKDTMATFECETSEPFVKVKWYKDG 2165



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)

Query: 1232  PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1285
             PK  + P  I      +    VRAG  + LF  V G      TW K      +++ +   
Sbjct: 12100 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12156

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
             V+  +  + L I  + ++  G Y+L + N  G +   VN+ V+D P P +     SD+  
Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12215

Query: 1346  SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1404
             +S  +SW     DGGS V  Y +E  ++  KTW  +    + TSF+V +L+P +EY FRV
Sbjct: 12216 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12275

Query: 1405  RAINVYGTSEPSQESELTTVGEKPEEP 1431
              A+N YG   P+   +     +   EP
Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEP 12302



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)

Query: 1228  PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             P   P    P  I+  PE +          +RAG ++ L+  V G  P   TW K    +
Sbjct: 13178 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13237

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             ++   + +++++  + L      +   G Y L +EN  G ++  + + V+D P PP    
Sbjct: 13238 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13296

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1397
                +I   S  ++W     DGGS + +Y ++  D+  K+W  + T C  TSF V +L   
Sbjct: 13297 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13356

Query: 1398  HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1428
               Y FRV A N YG  +P +  +     + P
Sbjct: 13357 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13387



 Score = 87.8 bits (216), Expect = 9e-17
 Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)

Query: 1237  PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    + +KV   RA  ++ LF  + G       W K    +  ++  ++E + + +
Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18664

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L I    +   G Y L +EN  GS+ A VN+ V+D P  P       +++  S+TLSW 
Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18723

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DGG+ + +Y +E  ++  K +  +   C  T+F +++L     Y FRV A N YG 
Sbjct: 18724 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783

Query: 1413  SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
               P++ +E   V E P  P     V        +V   T TI  E+  SD
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18825



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VRAG S  +     G      TW   R++ + ++ +++E   N ++L+I    +   G Y
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17596

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              L +EN  GS+ A V + V+D P PP       ++R  S  L W     DGG+ V++Y I
Sbjct: 17597 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17655

Query: 1369  EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             +  +S  K +  +++ C  TSF V++L     Y FRV A N +G   P +  +     E 
Sbjct: 17656 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17715

Query: 1428  PEEP 1431
             P  P
Sbjct: 17716 PSPP 17719



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             ++AGE +++   V G      +W+K  + ++++  + VE +   + L I    ++  G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             T+   N  G+    +++ V++KP PP G     ++ +  + +SW   +Y GG  + +Y +
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 17945

Query: 1369  EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             E  D+   TW  + AT   T+  +  L    EY+FR+ A N YG S P
Sbjct: 17946 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 17993



 Score = 85.9 bits (211), Expect = 3e-16
 Identities = 67/238 (28%), Positives = 104/238 (43%), Gaps = 21/238 (8%)

Query: 19   VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG- 77
            V P++ DS      P FI    N  I  G  A     V G P+P++ W  NG  +T    
Sbjct: 3443 VYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD 3502

Query: 78   -RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVV 136
             +F+ D       SL+I     ED G+YTC A+N  G        T+  ++ K     + 
Sbjct: 3503 YKFVFD---GDDHSLIILFTKLEDEGEYTCMASNDYGK-------TICSAYLK-----IN 3547

Query: 137  SKTLGDRFS---APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT 193
            SK  G + +   +   ++   + G CPP F  +L  +   +G    F   + G P P VT
Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607

Query: 194  WLKGNVPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            W K N  L  S   + +   NG     ++   ++D G+Y C   N  G+++ +AEL +
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 64/210 (30%), Positives = 99/210 (47%), Gaps = 11/210 (5%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE-GSIEVYEDAGSHYL 472
           P F    QS  V E  T  F   +SG P PEV+WF +G  +       +++    G   L
Sbjct: 6   PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA-PSFSSVLKDCAVIEGQDF 531
            +      +SG YS  A+N  GQ     T   E L   E A P+F   L+   V +G   
Sbjct: 66  TIPAVTKANSGRYSLKATNGSGQA----TSTAELLVKAETAPPNFVQRLQSMTVRQGSQV 121

Query: 532 VLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
            LQ  V G P P + +  +G  IQ +   + + E  +  L I +A PED GTY+  A N+
Sbjct: 122 RLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181

Query: 589 LGQVSCSAWVTV--HEKKSSRKSEYLLPVA 616
           +G+ + +A + V   E+  ++K++ ++  A
Sbjct: 182 VGRATSTAELLVQGEEEVPAKKTKTIVSTA 211



 Score = 85.5 bits (210), Expect = 4e-16
 Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+L P +    EG TA+F+ +V G P P+  W  +GQ I +     +     GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            I      D G++T  A N +G   ++V LTVE                       AVE  
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
                 +  P F  KL  V +KEG       + TG P P + WLK +  + P    ++ + 
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               G   L+I      D   YT   +N +G+ +   +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 65/256 (25%), Positives = 111/256 (43%), Gaps = 35/256 (13%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+   VA  + S  +L V+          E P  +   + + ++ G  A+F   + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221

Query: 62   PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P+++W++  Q +++G +  FL D      ++L++     ED   YTCEA N  G    + 
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             L+VE                      P V +        PP   T L   V  EGQ  R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
            F C+++G    +V+W   +  ++PS    +++      LEI     +D G YT +  N  
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376

Query: 240  GKASMSAELSIQGLDS 255
            G+ S +A LS++  +S
Sbjct: 3377 GQVSSTANLSLEAPES 3392



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)

Query: 1261  VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
             + G    + +W K    +     + VE+S   + L +   ++   G YT+ ++N  G+++
Sbjct: 13509 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
               +++ VV KP  P G     ++ + ++TL W     DGGS + +Y +E  DS N  W  
Sbjct: 13569 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13628

Query: 1381  LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
              A+  + T+F V  L    EY FRV A N YG  E
Sbjct: 13629 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13663



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)

Query: 1237  PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             PP+I    FP     VRAG ++++   ++G      T  +    ++ +     E +    
Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20035

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              + +  +     G Y +   N  G+ +A +N+ V+D+P PP G    SDI   S+TL W 
Sbjct: 20036 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20095

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                YDGGS V +Y +   +++   W E+ AT   T   V  L    EY+FR++A N +G 
Sbjct: 20096 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20155

Query: 1413  SE 1414
             S+
Sbjct: 20156 SD 20157



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)

Query: 1238  PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             P I++F  +      +++GES+ +   V G      TW K   +I++  +M++ +    +
Sbjct: 21458 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21517

Query: 1294  KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1353
              L +  A ++H G YT+  +N  GS +A++ + V D P    G    ++I    +TL W 
Sbjct: 21518 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21577

Query: 1354  GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1412
                 DG + +  Y IE  +++   W  +   C + S+    L+  +EY+FRV A+N +G 
Sbjct: 21578 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21637

Query: 1413  SEP 1415
               P
Sbjct: 21638 GRP 21640



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)

Query: 882  HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 938
            H EE+  QQ   +  +++    ++S   ++E   +  PA +      + + VKP+ +   
Sbjct: 676  HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726

Query: 939  SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 997
            SE   K    + +   S + K     T     V   P+ A+P F      K  +P     
Sbjct: 727  SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783

Query: 998  SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 1055
              A    +      K LS    +   + +  +  A T+KP      AE   L     A  
Sbjct: 784  YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840

Query: 1056 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1095
             +  KS +  E+KK+V   +       GTT  E+R E                       
Sbjct: 841  PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            T P     L++V V EG+ + L+C +S  P  T+ W      ++++    ++ +  +  +
Sbjct: 895  TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1213
             I +A  ED G + C A N+AG    SC   V V +    E T   E  +   K  +   
Sbjct: 955  MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014

Query: 1214 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                +D ++ ++ A    P A   P  I  P  QK+  G SV    +V G       W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071

Query: 1274 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
                +      KV  N + G  KL I     +  G YT++V NK G   A  +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 59/368 (16%)

Query: 405  MEGQRDSAFPKFESKP-------QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQ 457
            ++G++ +   K + +P         Q+V E   V+   +VS +   E  W  +G  V+  
Sbjct: 2294 IDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPS 2352

Query: 458  EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS 517
            +  + +  D  SH L +      D+G YS T       L  S + +V   +V  + P   
Sbjct: 2353 D-RVHIVIDKQSHMLLIEDMTKEDAGNYSFTIP----ALGLSTSGRVSVYSVDVITP--- 2404

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDAL 574
              LKD  VIEG   VL+C V    V  + W LN + I+     ++  +     L I    
Sbjct: 2405 --LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTH 2462

Query: 575  PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 634
              D G Y  +    +G+V  +  ++V + K                     ++GL DL  
Sbjct: 2463 ASDEGPYKLI----VGRVETNCNLSVEKIK--------------------IIRGLRDLTC 2498

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
             +   V   V++S +   +V+W     EI+ S  +  E  G  + L +  +  +D G YT
Sbjct: 2499 TETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYT 2557

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
                  AGE  T   LTV           ISKP    T +  Q  +  C +A +P     
Sbjct: 2558 F----YAGENMTSGKLTV-------AGGAISKPLTDQTVAESQEAVFECEVA-NPDSKGE 2605

Query: 754  WLRDGKAL 761
            WLRDGK L
Sbjct: 2606 WLRDGKHL 2613



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)

Query: 1086 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1144
            D E R++ +   AP  K   QD+ V  GK L +     + P A   W    + L T    
Sbjct: 6490 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6549

Query: 1145 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1204
              +++ S   +  +K    D+G YK V +N  G+AE    + V D P             
Sbjct: 6550 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6594

Query: 1205 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1264
                   PV   E   T   +               +    ++ +  G S ++ G V   
Sbjct: 6595 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6631

Query: 1265 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1322
            + I   TW+    + +  E       + G +     + +   G    +  +N + +R   
Sbjct: 6632 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6691

Query: 1323 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
                  D P PP      +D+    ++L+W    YDGG+ + +Y IE+ D  +  W    
Sbjct: 6692 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6744

Query: 1383 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
            T R+   S  V D++   EY FRVRA N  G  +PS  +    V +  E P   V ++  
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6804

Query: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1493
            D+ +  V  +      +        I ER   GK   +    +LV + T KV       K
Sbjct: 6805 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6864

Query: 1494 FFKAYSAKEKENIRQEISIMNCL 1516
            +    SA+ K  +     I+  L
Sbjct: 6865 YLYRVSAENKAGVSDPSEILGPL 6887



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             V+AG S  +     G       W K    ++   +  V+ +++ + LTI  A +   G Y
Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19758

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
             TL ++N L +    + + V+D P PP       D+   S  LSW     DGG+ V++Y I
Sbjct: 19759 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19817

Query: 1369  EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             E  +++ K W  +   C   S+ V +L     Y FRV   N +G   P++  E   + EK
Sbjct: 19818 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 19877

Query: 1428  PEEPK 1432
             P  P+
Sbjct: 19878 PSPPE 19882



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)

Query: 602   EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
             E + S  SE + P +     AP F + L +L V   S  T+  +V+G+P P V W   G 
Sbjct: 24410 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24469

Query: 662   EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
             EI  +   +  ++ +G  H L I  V  +D   Y   A N  G V   A L V+ P    
Sbjct: 24470 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24529

Query: 720   QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
              P  +    +V A  G+ V I    +G P P + W + G+ L  + GH++V+      +L
Sbjct: 24530 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24588

Query: 780   VLKK-VQPWHAGQYEILLKNRVG 801
             V    V+   AG Y +  KNR G
Sbjct: 24589 VFPNGVERKDAGFYVVCAKNRFG 24611



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 87/338 (25%), Positives = 138/338 (40%), Gaps = 26/338 (7%)

Query: 384  TRQPGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIP 441
            TR    G   VV+    +  ++ +EG RD      + + Q  E K+   V+F      + 
Sbjct: 3073 TRMSDAGKYTVVAGGNVSTAKLFVEG-RDVRIRSIKKEVQVIE-KQRAVVEFEVNEDDV- 3129

Query: 442  KPEVAWFLEGTPVRRQEGSIEVYE-DAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSW 500
              +  W+ +G  +  Q      Y  +   H + + + R  D+G Y+  A    G+   S 
Sbjct: 3130 --DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVA----GRNRSSV 3183

Query: 501  TLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--- 557
            TL V         P     L+   V  G+       + G P P+I+W    Q +      
Sbjct: 3184 TLYVNA----PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239

Query: 558  RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
            +   +     L + +A PED   YTC A+N  G  + SA ++V E       +  +PV P
Sbjct: 3240 KFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSV-EVPEVVSPDQEMPVYP 3298

Query: 618  SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 677
                 P  +  L D    +G       +VSG    +V W     +I+ S  F   Q    
Sbjct: 3299 -----PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDT 3352

Query: 678  HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            + L I E +PED GTYT  A N+ G+V + A L+++ P
Sbjct: 3353 YQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3390



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)

Query: 23    RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
             R D+M L E P  F LP  N     G   +F   +  +PEP VTW+++GQ I  G    +
Sbjct: 25182 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25241

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
             +  +   +G + L I++V  +D  +YT  A N  G      +LTV       L  P    
Sbjct: 25242 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25294

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             TL                    P F   L     +EGQ   F  +++G P P + W K  
Sbjct: 25295 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335

Query: 199   VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
              PL     +  + E      L I     +D G Y     N +G  S  A L ++ L    
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395

Query: 258   RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
             + F +  +     V+K++   +     L   E+
Sbjct: 25396 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25427



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1306
             V+AG+++ L   V G       W K +    +  S  +K++   + SK ++  A++   G
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775

Query: 1307  CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
              Y +   N  GS  A   + V+DKP P        D+ S   T+ W     DGG  +Q+Y
Sbjct: 11776 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11834

Query: 1367  SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1423
              +E  ++    W    AT  +    V  L+  +EY FRVRA N  GT  P++   +   T
Sbjct: 11835 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 11894

Query: 1424  VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1464
               +KP  P D  EV+   ++E  V +     +  + ++ ++
Sbjct: 11895 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 11934



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)

Query: 622   APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
             AP   + + D+    G    ++ Q+ G P P++ W   G E+ +S  +     G  H+L 
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094

Query: 682   IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
             +     ED G YTC A N  GEV T + L +Q       P +  K +   A +G ++ + 
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24152

Query: 742   CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 800
                 G P P + W   G+ L +++ +  +   E    LV+K VQ   HAG+Y++ L N  
Sbjct: 24153 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211

Query: 801   GECSCQVSLMLQN 813
             G     + + +Q+
Sbjct: 24212 GTVDAILDVEIQD 24224



 Score = 81.3 bits (199), Expect = 8e-15
 Identities = 94/402 (23%), Positives = 159/402 (39%), Gaps = 55/402 (13%)

Query: 416  FESKPQSQEVKENQTVK-FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCL 474
            F  + Q    KE  T+  F CE S  P  +V W+ +G  V   +    ++ D   H+L +
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGD-KYRMHSDRKVHFLSI 2187

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
            L   T D+  YSC     +   + +      +L V      F   L+D  V E     L+
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKTTA------KLIVEGAVVEFVKELQDIEVPESYSGELE 2241

Query: 535  CSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
            C V    +    W  N   ++       T   G   L ++D   ED G Y+ + +     
Sbjct: 2242 CIVSPENIEG-KWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---- 2296

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                       KK++ K +        KP     LQGLSD KV +G  V + V+VS    
Sbjct: 2297 -----------KKTTCKLKM-------KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV 2338

Query: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQ 707
             E +W+ +G E+Q S+  H       H L I+++  ED G Y+        +++G V   
Sbjct: 2339 -EGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVY 2397

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
            +V              I+  + V    G   ++ C ++     +V W  + + + K    
Sbjct: 2398 SVDV------------ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDR 2444

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
             + +       LV+ +      G Y++++  RV E +C +S+
Sbjct: 2445 VQAIVKGTKQRLVINRTHASDEGPYKLIV-GRV-ETNCNLSV 2484



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 171/811 (21%), Positives = 301/811 (37%), Gaps = 112/811 (13%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            + E ++  F  E+S    P   W L+G  + R   + E+  + G  +L L K +   +G 
Sbjct: 4911 IYEKESASFDAEISEADIPG-QWKLKGE-LLRPSPTCEIKAEGGKRFLTLHKVKLDQAGE 4968

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
                A NA         +    L V E+   F+  LKD  V E +    +C +  T    
Sbjct: 4969 VLYQALNA---------ITTAILTVKEIELDFAVPLKDVTVPERRQARFECVL--TREAN 5017

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
            + W      I+ +         + HI    D+  +D G YT   E    + S   +VT  
Sbjct: 5018 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGI 5075

Query: 602  EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
              K                    F+  L D  V +G   T   ++S +    V+W  N  
Sbjct: 5076 RLK--------------------FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDA 5114

Query: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
            ++  S        G  H L ++EV  +D      +      E+ + A L V E      P
Sbjct: 5115 KLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KELSSTAQLKVLE----ADP 5166

Query: 722  WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
            +F  K    TA     + + C ++ D    V W +DG+ +      + +  +     L +
Sbjct: 5167 YFTVKLHDKTAVEKDEITLKCEVSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKI 5223

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG--- 837
            KK      G+Y          C C       N +  A L +  +P    ++  G      
Sbjct: 5224 KKADLKDKGEYV---------CDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFE 5274

Query: 838  ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQ 889
             +    D +G     W  +GQ      D E +    K  +         T + + +A   
Sbjct: 5275 IELSEPDVHGQ----WKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANA 5330

Query: 890  QEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQ 949
            +    L  ++L    +    LS  D+K    ++  F   + R+  PKT     R +   Q
Sbjct: 5331 KSAANLKVKEL--PLIFITPLS--DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQ 5380

Query: 950  QV--DFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKA 1007
            ++  D R  L K GT  + V +       A   F +      +    +G    E +  K 
Sbjct: 5381 EITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKF 5434

Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEEL 1067
            +   K ++  +    +  V  +     +K   N +   T + + + + +    S + ++L
Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDL 5493

Query: 1068 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1127
              D  + +  +    G +   K +  +G  P F  KLQD    E  +++LQC++S    A
Sbjct: 5494 SIDDTSQIRVEA--MGMSSEAKLTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADA 5549

Query: 1128 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
             + W  +GK +K +K  ++  +G    + ++KAL  D G Y C    D G  + S ++ +
Sbjct: 5550 PVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5605

Query: 1188 DDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
            +D          E+K  RP  S+  V+ TE+
Sbjct: 5606 EDR---------EIKLVRPLHSV-EVMETET 5626



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)

Query: 1231  PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
             PPKA +  ++    +   +RAG  + L   V G       W K  K++   E + ++ + 
Sbjct: 22546 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603

Query: 1291  NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1350
               +   I    +   G YTL V+N  G++   V + V+D P  P G    S +     TL
Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22662

Query: 1351  SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             +W     DGG+ +  Y +E  +++   W  +   C + S+ V  L+ ++EY FRVRA+N 
Sbjct: 22663 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22722

Query: 1410  YG-----TSEPSQESELTTVGEKPEEPKD 1433
             YG      SEP       T+   P  P++
Sbjct: 22723 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22751



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)

Query: 1250  RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
             +AG+++++   V G    T TW K  + +++++ +  E +   + L I    +   G Y 
Sbjct: 14581 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14640

Query: 1310  LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             L   N +G     + + V D P PP G     ++ S  +T SW     DGG  + +Y +E
Sbjct: 14641 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14700

Query: 1370  IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1411
             +  + + TW ELA T   T++    L    EY+FRV+A N YG
Sbjct: 14701 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)

Query: 1738 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1797
            EED  +     ++E +  V+  F   I++  ++EG    F CK+ GYP P++ W+KD + 
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284

Query: 1798 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I+    +Q+D+ +DG  SL I  V  +D+  YT  A N  G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 157/770 (20%), Positives = 278/770 (36%), Gaps = 117/770 (15%)

Query: 21   PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
            P +++  P  EAP      ++  + +G+ A F  RV G P+P+  W++NG  I    R  
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079

Query: 81   LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
                      LVI  V  ED      +A N +G       L V+   AKQL         
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127

Query: 141  GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE-GQMGRFSCKITGRPQPQVTWLKGNV 199
                                  F  +L  VV KE   M  F C+ T  P  +V W K  +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166

Query: 200  PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
             +    +  +     +  L I  ++  D   Y+C++V        +A+L ++G   A   
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDE-NVKTTAKLIVEG---AVVE 2222

Query: 260  FVRETK--ATNSDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
            FV+E +          E+  ++S E+       + +E  +  K   + +RG       + 
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282

Query: 313  QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA---PGLGV 363
              +   E       K  +CK   +  P   +LQ  S     +   VQ E +       GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341

Query: 364  LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR---RIPMEGQRDSAFPKFESKP 420
                G+E  +P+         +   L  +D+  + A      IP  G   S      S  
Sbjct: 2342 WMKDGQE-VQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVD 2400

Query: 421  QSQEVKENQTVK-----FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                +K+   ++       C+VS      V W+L    + + +  ++         L + 
Sbjct: 2401 VITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVIN 2459

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
            +    D G Y        G++  +  L VE++ ++         L+D    E Q+ V + 
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKIKIIR-------GLRDLTCTETQNVVFEV 2508

Query: 536  SVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
             +  + +  + W    + I+ +   +      + +L + + + +D G YT  A    G+ 
Sbjct: 2509 ELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTFYA----GEN 2563

Query: 593  SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
              S  +TV               A SKP        L+D  V +  +     +V+ NP  
Sbjct: 2564 MTSGKLTV------------AGGAISKP--------LTDQTVAESQEAVFECEVA-NPDS 2602

Query: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +  WL +G  +  + +   E  G +  L I     +D G YT +   S    +T A L V
Sbjct: 2603 KGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATS----KTSAKLKV 2658

Query: 713  QEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
            +          I K  +++T +  Q  + +  +       V W+++G  L
Sbjct: 2659 EAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVL 2701



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 10/207 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHY 471
             P+F     ++     + V+F   ++  P+P V W+  G  ++  +   +     D G + 
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV---MEVAPSFSSVLKDCAVIEG 528
             L +    T D   Y+  A N  G+ SC   L V          + P F  +L +    EG
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEG 25312

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELHIQDALPEDHGTYTCL 584
             Q    +  V G P P + W  +GQP+    +      G+    LHI+D LPED G Y   
Sbjct: 25313 QSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVT 25372

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEY 611
             A N  G  SC A + V E+   +K E+
Sbjct: 25373 ATNTAGSTSCQAHLQV-ERLRYKKQEF 25398



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)

Query: 1225 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1276
            +P+  TPP  A+ P  I  P+       +V+ G+ + L   ++G+   T TW+K      
Sbjct: 8167 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224

Query: 1277 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1310
                             ++QE E         + ++NS+ G S+L +  + +   G Y +
Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284

Query: 1311 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1370
             VEN  G  +A   ++V+D P PP       DIR +S+   W     DGGS + +Y++E 
Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8343

Query: 1371 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1427
             D    +  W  + +T R   ++V  L+   EY FRVRA N +G   P     L  V + 
Sbjct: 8344 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8401

Query: 1428 PEEPKD 1433
            P  P D
Sbjct: 8402 PFGPPD 8407



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 164/786 (20%), Positives = 281/786 (35%), Gaps = 119/786 (15%)

Query: 36   ILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIH 94
            I P +++ + EG  A  E +V       V W+ N + I    R  +   ++GT   LVI+
Sbjct: 2402 ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDR--VQAIVKGTKQRLVIN 2459

Query: 95   AVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
              H  D G Y        G  +    L+VE                              
Sbjct: 2460 RTHASDEGPYKLIV----GRVETNCNLSVEKI---------------------------- 2487

Query: 155  IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
                   K    L  +   E Q   F  +++      V W   +  ++PS++  +     
Sbjct: 2488 -------KIIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKPSSKYKIEAHGK 2539

Query: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV--R 272
            +  L +  + +DD G YT      +G+   S +L++ G  + ++    +T A + +    
Sbjct: 2540 IYKLTVLNMMKDDEGKYTFY----AGENMTSGKLTVAG-GAISKPLTDQTVAESQEAVFE 2594

Query: 273  KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPW---AANSQPQPPRESKLESCKDSP 329
             EV N  SK   L   +    + N  S   G        A           K+ + K S 
Sbjct: 2595 CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA 2654

Query: 330  RTAPQTPVLQKTSSSITLQAARVQ------PEPRAPGL-----GVLSPSGEERKRPAPPR 378
            +   +   ++KT  ++T+   +          P   G+     GV+  S E+        
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT 2714

Query: 379  PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVS 438
              +   +   +  + V      R +    +      K   KP+     EN TV F   VS
Sbjct: 2715 IYSLRIKNCAIVDESVYGFRLGR-LGASARLHVETVKIIKKPKDVTALENATVAFEVSVS 2773

Query: 439  GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSC 498
                P V WF +   ++  +    +  +   H L L      D+G Y+       GQL C
Sbjct: 2774 HDTVP-VKWFHKSVEIKPSDKH-RLVSERKVHKLMLQNISPSDAGEYTAVV----GQLEC 2827

Query: 499  SWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 558
               L VE L +       +  +K+  V E +    +C V    VP + WL NG  I+ + 
Sbjct: 2828 KAKLFVETLHI-------TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSE 2879

Query: 559  S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 615
                  +  + +L I +   ED   YT +  N   QVS +  VT                
Sbjct: 2880 KFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN--DQVSATLTVT---------------- 2921

Query: 616  APSKPTAPIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 674
                   PI +   L D+   +   +T  V V+        WL NG EI+ ++      +
Sbjct: 2922 -------PIMITSMLKDINAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTK 2973

Query: 675  GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
               HSL I+ V   D   YT      AG+  + A L V+  H      F    + +    
Sbjct: 2974 KLTHSLNIRNVHFGDAADYTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLE 3025

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             +  +  C ++ +P  TV W++D + L + T   ++ + + V  L++   +   AG+Y +
Sbjct: 3026 KKRAMFECEVS-EPDITVQWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083

Query: 795  LLKNRV 800
            +    V
Sbjct: 3084 VAGGNV 3089



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)

Query: 1228 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
            P T   A + P   +  F +  +V     + +    TG    T TW    K ++  + +K
Sbjct: 6886 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 6945

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1345
            ++     ++L I  + +   G YTL +EN++ +   ++++ V+ +P  P       DI  
Sbjct: 6946 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7004

Query: 1346 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ L+W     DGGS +  Y +E  + + KTW K +       F V DL+   EY F+V
Sbjct: 7005 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7064

Query: 1405 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1433
             A N  G  EP+   E   ++T    P+ P++
Sbjct: 7065 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7096



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PA  ++L  V  ++   +L   +   D  + I   L     K + F + +      + ++
Sbjct: 22049 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22108

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             E+ + +    ++  AKNDAG +E                         P+ +   V+   
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22140

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
                 +K+     T     +  Q+I        +AG    +   ++G      TW     +
Sbjct: 22141 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22190

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
             ++E++ + +  +++ + LT+  + +   G Y L +EN  G +   V + V+ +P P  G 
Sbjct: 22191 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22250

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1396
                S + + S  LSW      GG+ + +Y +E  +S    W+ + ++ + T   V  L  
Sbjct: 22251 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
               EY FRV + N +G S+P + + +  + E P  P
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22343



 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 85/361 (23%), Positives = 146/361 (40%), Gaps = 24/361 (6%)

Query: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
            S+DVV    +      G  + A P F +KP  Q++ E  +V F C+V G PKP V W   
Sbjct: 1013 SRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKS 1072

Query: 451  GTPVRR-QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
            G P+       +   +  G   L +      D+G Y+    N  G+ S S +L +E    
Sbjct: 1073 GVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131

Query: 510  MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 567
              +  S   +L    V     FV +  V G   P   +    +  +  ++     +A+  
Sbjct: 1132 ELLMKSQQEMLYQTQVTA---FVQEPKV-GETAPGFVYSEYEKEYEKEQALIRKKMAKDT 1187

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--KSSRKSEYLLPVAPSKPTAPIF 625
            + ++  + +     +   E  + ++      T  E+  +   + +  + ++ S+     F
Sbjct: 1188 VVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVESGF 1247

Query: 626  LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQ 683
               + + ++++G  VT   ++SG P P++ W  +G  I+  E +   F Q G + SL I 
Sbjct: 1248 DSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDG-RASLRIP 1306

Query: 684  EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS-----------KPRSVTA 732
             V PED G YT  A N  G       L V+       P +I             PRSV+ 
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366

Query: 733  S 733
            S
Sbjct: 1367 S 1367



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P  K       V  G+ L ++  +S  P  TI WT +G  LK T  I ++    L ++SI
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16792

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y     N  GQ   S ++   D P  +  K P                  
Sbjct: 16793 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16835

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              D + +       PP      QI  +   ++                   T  W      
Sbjct: 16836 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 16879

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1332
             +  +  +KV   + G++             + +  EN+ G   A  +  +V      +P 
Sbjct: 16880 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 16927

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1385
             PP GTP A+ I   S+ + W+    +GGS V  Y +E       +W   NKT        
Sbjct: 16928 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 16981

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              T F  Q+L    EY+FRV A N+ G  + S+ SE     +  + P
Sbjct: 16982 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17027



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F + L+D  V E    +  CQ+S +  A + W  NG+ +K  K     ++GS+  + I+ 
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1206
               +D   Y C  ++   +A    + + V+         +AP ++     E+   +    
Sbjct: 6387 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6446

Query: 1207 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1241
              ++++  V G +                           + K    +   + A  P+I 
Sbjct: 6447 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6506

Query: 1242 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1301
               +D  V  G+ + +             W K  + +       ++ +   +   IL A+
Sbjct: 6507 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6563

Query: 1302 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1361
            +   G Y ++++NK G  +  +NL V+D P P       ++     ++L+W     DGGS
Sbjct: 6564 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6622

Query: 1362 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1418
             +  Y +E  D   KTW  LAT R+ S  F V  L     EY FRV A N  GT EP + 
Sbjct: 6623 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6681

Query: 1419 SELTTVGEKPEEPKDEVEVSDDD 1441
                    K + P   + V+  D
Sbjct: 6682 DNPVEARSKYDVPGPPLNVTITD 6704



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)

Query: 1721 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
            S TG+       E L   E  V++        E P   P     ++++ V+EG +   +C
Sbjct: 859  SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             I GYP P V W+++D  I  S  FQI + + G   L+I +   +D  ++TC AVN  G 
Sbjct: 919  HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977

Query: 1840 ATCTAELIVETMEEGEGE 1857
             + +  L V+  EE E E
Sbjct: 978  VSTSCYLAVQVSEEFEKE 995



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)

Query: 619  KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 678
            K   P+    L D    +G  V +T  ++     EV W      +   E F   Q    +
Sbjct: 4239 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4296

Query: 679  SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 737
            +L I +V  ED  G Y CEA N +G+  T A LTV +      P    K   +  +LG  
Sbjct: 4297 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4353

Query: 738  VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
               +C I   P     W + G+ +  ++    +  ++ + +L + + Q    G+Y     
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4412

Query: 798  NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
            N  G  SC  +L +         R L   R+P   E++                S+    
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4459

Query: 854  PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 913
            P   +  +E +  E V    K+         + + + EV  +  R+   +K+   T   +
Sbjct: 4460 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4512

Query: 914  DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 970
                IP    + +   + +V   KP  V  E   + +P  V    V+ KK  +K P  E 
Sbjct: 4513 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4569

Query: 971  VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 1027
              P  P       + G  KK P+   +   +       E      P +    + PLK V 
Sbjct: 4570 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4622

Query: 1028 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1073
              K     +   +G++   E L     A     K   N++ + K     D K+       
Sbjct: 4623 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4682

Query: 1074 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1124
                   +  C  + G+   T   K    +      K   ++V V +G+ L L C+++ +
Sbjct: 4683 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4742

Query: 1125 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1183
                ++W  +GK  ++    I+    G + +++I  A   D G Y    +N A   ECS 
Sbjct: 4743 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4799

Query: 1184 QVTV 1187
             V V
Sbjct: 4800 CVKV 4803



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)

Query: 1052 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1105
            N++P ++LK   +E +  D +  +  +  +A G ++  + SE+         P    +  
Sbjct: 7838 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 7897

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            D+ V EG+KL +     + P  T+ W  +GK +K +  + +  +     + + K++  D 
Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 7957

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            G+Y    +N  G A  S  V V   P        ++K+              SD T    
Sbjct: 7958 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 7999

Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                 PP+                             G  PI   ++  R++     ++ 
Sbjct: 8000 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8031

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1343
            V + EN    T+          + +   NK+G  +     N  +   P  P   P   ++
Sbjct: 8032 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8091

Query: 1344 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1395
             +    ++T++W    YDGGS +  Y IE      + WK    C        ++  + L 
Sbjct: 8092 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8148

Query: 1396 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1442
               EY+FRVRA N  G SEPS+ +  T   +  + PK      +EV   DE
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8199



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 90/389 (23%), Positives = 159/389 (40%), Gaps = 47/389 (12%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            VKE Q V F CEV+     +  WF     +      I + +D   + L +  A   D   
Sbjct: 6154 VKEQQEVVFNCEVN-TEGAKAKWFRNEEAIFDSSKYIILQKDL-VYTLRIRDAHLDDQAN 6211

Query: 485  YSCTASNAQGQ-LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
            Y+ + +N +G+ +  +  L VE   +  V P     LKD   +E +     C V    V 
Sbjct: 6212 YNVSLTNHRGENVKSAANLIVEEEDLRIVEP-----LKDIETMEKKSVTFWCKVNRLNVT 6266

Query: 544  RITWLLNGQPIQYARSTCEAGVAELH---IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
             + W  NG+ + +            H   I+D    D G Y                VT 
Sbjct: 6267 -LKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYI---------------VTA 6310

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
             + KS   +E L+  AP++     F++ L D  V +      + Q+S      V W  NG
Sbjct: 6311 GQDKSV--AELLIIEAPTE-----FVEHLEDQTVTEFDDAVFSCQLS-REKANVKWYRNG 6362

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-PHDGT 719
             EI+E + + FE+ G+ H L I++   +D   Y C       + +++A L V+E P +  
Sbjct: 6363 REIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYAC----GVEDRKSRARLFVEEIPVEII 6418

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
            +P     P+ +  + G  V+    +  D    V WLR+   + +   H +++    +  L
Sbjct: 6419 RP-----PQDILEAPGADVVFLAELNKDKV-EVQWLRNNMVVVQGDKH-QMMSEGKIHRL 6471

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             +  ++P   G+Y  + K++      +++
Sbjct: 6472 QICDIKPRDQGEYRFIAKDKEARAKLELA 6500



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V+V  G  L +   +S  P   +  + +G  LK T            ++++++++  D G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1224
              Y+  A N +G  +    + V D P                   P V+   TE   T+K 
Sbjct: 20049 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20094

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P PK    + +   I+       ++   S  ++ +V+ T  +  T MK  K     E+ 
Sbjct: 20095 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20144

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1344
                 +EN                    + + + S    V L     P PP+ TP  +++ 
Sbjct: 20145 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20185

Query: 1345  SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1402
               S+T+ W+    +GGSAV  Y +E+ D  +  W++      R+T F V  +     Y+F
Sbjct: 20186 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20245

Query: 1403  RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1462
             RV A N  G  +PS  SE     +  E P++ V ++D  +    + ++    +   K++ 
Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20304

Query: 1463  FYDIEER 1469
              Y +E R
Sbjct: 20305 -YIVERR 20310



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 33/91 (36%), Positives = 56/91 (61%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P+F K ++ +   +G  A F+  + G P P V WFK+++ +  S ++ I ++ +G+ + I
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            ++D   +D   Y CKA N LGE+TC AEL+V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)

Query: 1275  RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1328
             R+++ ++    +++   G+ L +   ++     + +  EN+ G      S +     T +
Sbjct: 23770 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23829

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1386
             + P+PP+  P   D+  SS++LSW     DGGS V  Y IE  +++   W         +
Sbjct: 23830 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 23889

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1437
             T + V  L+PD EY+FR+ A N  G SE S  SE        +KP +P  E+E+
Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 23942



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)

Query: 1228 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
            P+ PP   +    +      ++ AG+++ +   VTG    T  W K   ++ + + + ++
Sbjct: 8601 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8656

Query: 1288 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1347
            N    S+L I  A ++  G Y +   N  GS+ A   + V D P P          R   
Sbjct: 8657 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8716

Query: 1348 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1407
            L L+W     DGGS +  + IE  D+   TW++      +  ++  LL   EYKFRV A 
Sbjct: 8717 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8775

Query: 1408 NVYGTSEPSQESELTTV 1424
            N +G   P +   +  V
Sbjct: 8776 NKFGCGPPVEIGPILAV 8792



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 74/293 (25%), Positives = 111/293 (37%), Gaps = 39/293 (13%)

Query: 13   SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
            +  SLSV+   V S    MP+   PA I P ++    EG  A+F+ RV G  + +V+W+ 
Sbjct: 3276 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3333

Query: 69   NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE---- 124
              + I    RF        T+ L I   + ED G YT  A+N  G    T  L++E    
Sbjct: 3334 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPES 3392

Query: 125  ---------------------------GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
                                       G  + +L    +++TL     +P   T+     
Sbjct: 3393 ILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKFDSEK 3452

Query: 158  E-CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
            E   P F  ++    +  G +   S  + G P+P++ W    V L PSA           
Sbjct: 3453 EGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDH 3512

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269
             L I     +D G YTC+  N  GK   SA L I      ++    E+    S
Sbjct: 3513 SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKS 3565



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             +D P PPA    A D   SS+TL W    YDGGSAV  Y +EI     + W  ++T    
Sbjct: 20667 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20725

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             R+T + V +L P   Y FRV A+N  G  EP + +E     +  E P+ +++V+
Sbjct: 20726 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20779



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)

Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1324
            P T  W++  K   +    +V+   N  K             + +L EN  G  +   + 
Sbjct: 7427 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7475

Query: 1325 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
              + + D  DPP   G P   D+  +S+ L+W    +DGG+ ++SY IE+  +    W  
Sbjct: 7476 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7535

Query: 1381 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1437
            +A    +T   +  L+   EY FRVRA+N  G SEPS+ S+     EK  P  P   +EV
Sbjct: 7536 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7595



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+  +VA +   ++S+SV  + V+++     P F+   +N+ IKEG+  + + R  G P 
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538

Query: 62   PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P + W +N   I      +  ++ G +G  +L I +   +D   YT  A N +G      
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597

Query: 120  ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
            ++ VE  FA+   +  +    G       +AP +E     +G              +  P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657

Query: 162  KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             F  KL  + +K      F C++T  G P   V WL    PL+ + R+ +  + G   L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
                   D G+ TC   N  G    SA L ++      +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)

Query: 1091 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
            SE +GT P F +++ +  ++ G    L   V   P   I W  NG  L  +       +G
Sbjct: 3450 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3509

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               S+ I     ED G Y C+A ND G+  CS  + +       N+K    K        
Sbjct: 3510 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3555

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
                 TE+++ V K       P    PP  ++  +  +   G        V G    T T
Sbjct: 3556 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1329
            W K  KQ+  S +  + ++ NGS   I+   ++E  G Y    EN LG       L V+ 
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3667

Query: 1330 KPDPPAGTPC 1339
            +      TPC
Sbjct: 3668 EDTDMTDTPC 3677



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V V  G  + L+      P  +I W  +G  LK ++F+  S+  +  ++SI+ A  E  G
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y  +  N        C++ V   P +  T  P  K + P                    
Sbjct: 21136 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21166

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1283
                           I+F E +     +SV L   V    G   ITC  ++ R+  Q +  
Sbjct: 21167 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21208

Query: 1284  MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1337
             M   + +    K+  L    E+   + +  EN+ G  Q  V+  +V K     P PP G 
Sbjct: 21209 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21265

Query: 1338  PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1395
             P   ++ S  ++L+W    YDGGS V  + +E  +  +  W+++ T       +    L+
Sbjct: 21266 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21325

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1455
                +Y+FRV A N  G S PS  S+  T+   P +P    +  D       V   T+T+ 
Sbjct: 21326 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21377

Query: 1456  TEQKVSD------FYDIEERLGSGKF 1475
                 + D       Y IE+R G+ ++
Sbjct: 21378 WNPPLRDGGSKIVGYSIEKRQGNERW 21403



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 172/805 (21%), Positives = 281/805 (34%), Gaps = 128/805 (15%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G+V   A + I+   L+V    +D         F +P +++ + E   A+FE  +    E
Sbjct: 4967 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5015

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W +    I S  +F +    +    LVI+    +D G YT E              
Sbjct: 5016 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5060

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
             VEG            K    R     +            KF + L    VKEG+   F 
Sbjct: 5061 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5097

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C+++   +  V W K +  L  S  V +S +     LE+  V  DD+      V     +
Sbjct: 5098 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQV----KE 5152

Query: 242  ASMSAELSIQGLDSANRSFVRETKATNSD-------VRKEVTNVISKES----------- 283
             S +A+L +   D      + +  A   D       V K+V     K+            
Sbjct: 5153 LSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSI 5212

Query: 284  KLDSLEAAAKSKNCSSPQRG------GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
            K D L    K K      +G      G+    AN   +  R  K+E     P    +  V
Sbjct: 5213 KADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVE-ARLIKVE----KPLYGVEVFV 5267

Query: 338  LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
             +     I L    V  + +  G  + +    E               Q G+ + +V  +
Sbjct: 5268 GETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGM-TGEVSFQ 5326

Query: 398  AANRRIPMEGQRDSAFPKFESKPQSQ-EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRR 456
            AAN +      +    P     P S  +V E    KF CEVS  PK    W L+GT    
Sbjct: 5327 AANAK-SAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPK-TFRW-LKGTQEIT 5383

Query: 457  QEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF 516
             +   E+ +D   H + +  A   D   Y   A +              +L +  +   F
Sbjct: 5384 GDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTS---------GKLIIEGIRLKF 5434

Query: 517  SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPE 576
             + LKD    E +  V    +    + R+ W  N Q +   RS        + +QD    
Sbjct: 5435 LTPLKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSMQDEGKT 5485

Query: 577  DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
               T+  L+ +   Q+   A            SE  L V       P F   L D   ++
Sbjct: 5486 HSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQDYTGVE 5534

Query: 637  GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
              +V +  ++S    P V W  +G EI+ S++   +  G +  L +++    D G YTC+
Sbjct: 5535 KDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCD 5593

Query: 697  AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
                 G  +T   L +++     +   +    SV     ++      I+ D     +W  
Sbjct: 5594 ----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI-HANWKL 5644

Query: 757  DGKALCKDTGHFEVLQNEDVFTLVL 781
             G+AL + T   E+ +   + +LVL
Sbjct: 5645 KGEALLQ-TPDCEIKEEGKIHSLVL 5668



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L  + V  G K+ L   V+  P   I WT     LK  K I +       +V+I  +   
Sbjct: 7200 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7259

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y   A N  G+A    +V V D P                   PP     +D T +
Sbjct: 7260 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7301

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                   PP+     +I  +  +++    E                 W K    ++++  
Sbjct: 7302 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7345

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1339
                      K T L   +E+   + +  EN  G     Q + +T   + DPP G P   
Sbjct: 7346 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7392

Query: 1340 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1396
              SDI   ++TL+W     DGGS +  Y +E  D     W        + T++ V+ L  
Sbjct: 7393 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7452

Query: 1397 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
              +Y+FRV A N+ G  +PS+ +E   + +  + P
Sbjct: 7453 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7487



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1815
            P F++ ++ + V+EGS A F+  I G+P PEV WF+D Q I  S     QI +  DG   
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            L I  V   +  +Y+ KA N  G+AT TAEL+V+
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)

Query: 1217  ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
             ESD  V + P      P TP   A+    +     + V  G S  +   +   +  +  W
Sbjct: 16913 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 16972

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
              K  K I      K +N E G +             + +  EN +G  +A  N       
Sbjct: 16973 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17021

Query: 1332  DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1387
             DP  P GTP    ++ + +TL W    YDGGS +  Y +E  D  +  W + +      T
Sbjct: 17022 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17081

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1438
              F V  L  D  Y+FRV A N  G  S+PS  +   T  ++ E P        +D + V+
Sbjct: 17082 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17141

Query: 1439  DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1495
               +    E D     + T + +    +IEE          F+  L+ K   ++  G++  
Sbjct: 17142 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17201

Query: 1496  KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1554
             +A +    ++    + +++    P+  VQ      EK ++     +  GG      + E 
Sbjct: 17202 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17261

Query: 1555  FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1598
              E       +   E +    +++   EG EY+ +            IM VNK G
Sbjct: 17262 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17303



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1357
             GC   Y +  EN  G         ++   DP     P   P   D   +++T++W    +
Sbjct: 19553 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19612

Query: 1358  DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             DGG+ +  Y++E   S +  WK  + + R T + +  L    EY FRV+++N  G S+PS
Sbjct: 19613 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19672

Query: 1417  QESELTTVGEKPEEPKDEVE 1436
               S+     E+ EEP  +++
Sbjct: 19673 DSSDPQIAKEREEEPLFDID 19692



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 104/480 (21%), Positives = 172/480 (35%), Gaps = 84/480 (17%)

Query: 263   ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
             E     S  ++EVT +   E + +  + A +  + S+ +     R  SP +         
Sbjct: 25732 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25791

Query: 311   --NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSG 368
                S+PQP  E + ++ + SP     TP                +  PR+P     SP  
Sbjct: 25792 LIRSRPQPAEEYEDDTERRSP-----TPE---------------RTRPRSP-----SPVS 25826

Query: 369   EERKRPAPPRPATFP--TRQPGLGSQDVVSKAANRRIPMEGQRDSAF---PKFESKPQSQ 423
              ER      R A F   +R   + +     K + R+  +  Q+       P+   + +S 
Sbjct: 25827 SERSLSRFERSARFDIFSRYESMKAALKTQKTSERKYEVLSQQPFTLDHAPRITLRMRSH 25886

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              V   Q  +F   V   P  EV W+  G  ++ +   I     +G   L +L   T DSG
Sbjct: 25887 RVPCGQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSG 25945

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR-GTPV 542
             TY    +N +G+ S   TL V                       G D+    S R    V
Sbjct: 25946 TYRAVCTNYKGEASDYATLDVT----------------------GGDYTTYASQRRDEEV 25983

Query: 543   PRITWLLNGQPIQYARST------CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
             PR  +    +   YA S+       EA  +   ++  + E   + +    +A  ++  +A
Sbjct: 25984 PRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAA 26043

Query: 597   WV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
                 ++ EK ++RK +  L        A   L     + V +G     +    G P P V
Sbjct: 26044 LEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095

Query: 655   IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
              WL  G  +  S          + +  I  V   D G Y+    NS G+   +  LT+Q+
Sbjct: 26096 TWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQK 26155



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 90/366 (24%), Positives = 127/366 (34%), Gaps = 79/366 (21%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             L  AP   L  R+  +  G   +F   V+  P  +V W+ NG  +    +        G 
Sbjct: 25873 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 25931

Query: 89    FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
              +L I   H +D G Y               T + T G               R V  EL
Sbjct: 25932 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 25991

Query: 122   TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
             T   ++A    K+  +   S ++ +   +   ETR S+                      
Sbjct: 25992 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26050

Query: 158   ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                           +  TK   + V EG+  RFSC   G P P VTWL+    L  SAR 
Sbjct: 26051 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26110

Query: 208   SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
              V+        EI  V   D G Y+ +V N  GK      L+IQ      ++ V E KA 
Sbjct: 26111 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26163

Query: 268   NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
              S  R     V S E ++ S EA    K   SP+    P       P   + +  E  + 
Sbjct: 26164 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26214

Query: 328   SPRTAP 333
              P +AP
Sbjct: 26215 LPVSAP 26220



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 55/191 (28%), Positives = 77/191 (40%), Gaps = 11/191 (5%)

Query: 444  EVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD-SGTYSCTASNAQGQLSCSWTL 502
            EV W+ E   V   E   +  +D  ++ L + K  T D  G Y C A N  G+ + S  L
Sbjct: 4271 EVNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKL 4329

Query: 503  QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE 562
             V    V   AP     ++   V  G      C ++  P  R  W   G+ I Y    C 
Sbjct: 4330 TV----VKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCS 4384

Query: 563  AG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
                  ++ L I      D G YTC A N  G VSC+A +TV      +K   LLP    
Sbjct: 4385 IRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPERKP 4444

Query: 619  KPTAPIFLQGL 629
            +P   + L+ +
Sbjct: 4445 EPKEEVVLKSV 4455



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)

Query: 1098  PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
             P    KL  V  V  G  + L+  V   P   + WT +      T+   + +        
Sbjct: 11704 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11763

Query: 1155  VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1213
              S+ KA   D G Y   A N AG       V V D P    N K  ++ S R        
Sbjct: 11764 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11815

Query: 1214  LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
                    TV   P P+      +   I++  E +++                     W  
Sbjct: 11816 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11848

Query: 1274  FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1330
             +   +             G+ +T L    E+   + +  ENK+G+     +  V+ K   
Sbjct: 11849 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 11896

Query: 1331  -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
                  PDPP  T  + +     +T+ W    YDGG ++  Y +E  +  +  W  +  + 
Sbjct: 11897 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 11952

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                    VQ+LLPDHEY+FRV+A N  G  EPS  S    V + P EP
Sbjct: 11953 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 11999



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ +      +V   ++L +       P AT+ W  +G+TLK T  + +S   ++ S+SI
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 18957

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++A  ED G Y+    N AG       + V D P                   PP     
Sbjct: 18958 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 18999

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1277
              + +         PP+     QI  +  ++K                +  + TW    + 
Sbjct: 19000 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19043

Query: 1278  IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1333
             +  +  +K+     GS+             + +  EN+ G      +  VV +    P  
Sbjct: 19044 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19091

Query: 1334  PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1386
             P GTP       S++ ++W     DGGS V  Y +E       +W  ANK          
Sbjct: 19092 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19146

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1446
             T   V  L     Y++RV A N+ G  + S+  E       P +P  + EV++   K   
Sbjct: 19147 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19205

Query: 1447  VDYRTVTINTEQKVSDFYDIEERLGSGKF 1475
             + +     +   K++ +      L  G++
Sbjct: 19206 LKWSKPHYDGGAKITGYIVERRELPDGRW 19234



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)

Query: 1091  SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1150
             S+    APAF  + +  ++ EG+ +L  C++S +P   I W  N   +  +  + +S+  
Sbjct: 26630 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26689

Query: 1151  SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1194
             ++ S+ I  A   D G Y   AKN  GQ   +  + V    + P+ E             
Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26749

Query: 1195  --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1235
               ++++ +M + + ++S      + + +  + K A  +    +                 
Sbjct: 26750 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809

Query: 1236  --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
                                 +PP+I   P D  +  G+ + +    TG      TW    
Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869

Query: 1276  KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             ++I  QE     +EN+++ + L I+  +++  G YTL + N+ GS  A VN+ +
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)

Query: 1737 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
            S +  S A L   AE  P   P F + ++ + V +GS  R   ++ G P P V +++D  
Sbjct: 86   SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142

Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I+ S  FQI  + D   SL+I++   +D   Y+  A NS+G AT TAEL+V+  EE
Sbjct: 143  EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1154
            P   Q+LQ V V  GK       +S  P   I W    + L T    KF+   QE +L  
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            +   +A PED  +Y C AKND G A  S  ++V+          PE+ S  P   +P   
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP II   +D     G+      +V+GT  +  +W   
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             K+I+ S   ++   E+  +L I  A  E  G YT +  N +G   +  NL++
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)

Query: 1104  LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
             ++ + V  G  +     +   P  T  WT +G  +KT +   +  +     ++I+  L  
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11079

Query: 1164  DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             D G Y+    N AG    +  +TV D P              P   +  +  T    T+ 
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11127

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P    P      P I    E Q  R     + +G V+                     
Sbjct: 11128 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11158

Query: 1284  MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1336
                    +GS  T L       GC   + +  ENK+G      +   V K    P  P G
Sbjct: 11159 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11211

Query: 1337  TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1390
              P  +DI  ++ T+SW     DGGS +  Y +E       W   NKT           F 
Sbjct: 11212 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11266

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
             V  L   + Y+FRV A N+ G S+PS  S+
Sbjct: 11267 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11296



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + L   V   P  T+ W  +G  LK  + I ++ + +LC++ +     +D G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1224
                A+N +G    + ++ V D P    + K  +M S R   S  P L   G+E    +  
Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 12929

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             K     P  A                         +V+ T PIT   ++  K I+  E+ 
Sbjct: 12930 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 12962

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1340
                                    + +  ENK G          + K   DPP     P  
Sbjct: 12963 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 12999

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
             S+I    +T+SW   + DGGS +  Y +E  ++    W ++        +     L    
Sbjct: 13000 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13059

Query: 1399  EYKFRVRAINVYGTSEPSQESE 1420
             EY+FRV AIN  G  +PS  S+
Sbjct: 13060 EYEFRVTAINKAGPGKPSDASK 13081



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)

Query: 1083  GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1134
             G +D    S+ Q      ++ L D+     K L+++   S          P   ++W+  
Sbjct: 19667 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19726

Query: 1135  GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
                L+T  ++  +   S  S++IE A   D G Y    +N    A  +  V V D P   
Sbjct: 19727 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19782

Query: 1195  NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1254
                             PP   T  D T +          A +   +   PE+        
Sbjct: 19783 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19807

Query: 1255  VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1312
                     G  P+    ++ R   + S+   V  + N ++L+      +    Y   V  
Sbjct: 19808 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19856

Query: 1313  ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1369
             EN+ G     + +  + + +KP PP      S I   S++L+W    +DGGS +  Y +E
Sbjct: 19857 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 19915

Query: 1370  IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1429
               +   K W + A  +ST   V  L  + EY FRV A N  G S+P +      + E+ E
Sbjct: 19916 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 19975

Query: 1430  EPKDEVE 1436
              P+ +++
Sbjct: 19976 PPEIDMK 19982



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            + +  GK L +   V+  P  T +WT     L   + +++   G+   + I+ AL +D G
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8675

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
             Y   A N  G    + +V V D P              P   L PV+ T     +    
Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8721

Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
             P+    + +   II+  +D K+            T  QPI            E+E  K 
Sbjct: 8722 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8757

Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1342
            +       +T L   QE+   + ++ +NK G     ++  +  VD   PP        ++
Sbjct: 8758 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8808

Query: 1343 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1400
               S++TL W     +GGS +Q Y IE        ++ +    C +TSF V++L     Y
Sbjct: 8809 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8868

Query: 1401 KFRVRAINVYGTSEPS 1416
            +FRV+A+N  G SEPS
Sbjct: 8869 EFRVKAVNEIGESEPS 8884



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G+   L+  VS  PP T+ W+ +GK L+ T  + +       ++  + +   D G Y   
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A N  G A+    V V D P              P      V    S+  V     P   
Sbjct: 15039 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15085

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I+Q  E  ++                     W     ++Q ++         
Sbjct: 15086 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15116

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1346
               K+T L    E+   + ++  NK G  +   +  V+       PDPP   P  + I   
Sbjct: 15117 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15172

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+ + W     DGGS + +Y +E  D A + W +    T     + V  L   HEY+FR+
Sbjct: 15173 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15232

Query: 1405  RAINVYGTSEPSQES 1419
              A N  G S PS  S
Sbjct: 15233 MAENAAGISAPSPTS 15247



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +L EN+ G     +   ++   ++P PP G     D+  +S++LSW    +
Sbjct: 15519 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15577

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             DGGS +  Y +E+    +  W   AT + T   +  L+   EY FRV A N  G S+P Q
Sbjct: 15578 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15637

Query: 1418  ES 1419
              S
Sbjct: 15638 LS 15639



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PP+  P   D    S++L+W    YDGG+ +  Y +E+ +     W  +   AT R+T
Sbjct: 22845 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 22903

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
              F V DL    +Y FRV A+NV G SE S+        E+ E P  ++E++DD +K
Sbjct: 22904 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 22957



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
             +AP F    RNL ++  + A    +V G+P+P V W+R G+ I + G ++ +     G  
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488

Query: 90    SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
              L+I +V ++D   Y   ATN  G+   T  L VE      L                  
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24530

Query: 150   ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
                        PK    +G V    G++       +G+P P +TW KG   +  +    V
Sbjct: 24531 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24579

Query: 210   SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
                     L   +GV + D G Y     N  G    + EL +  +    R          
Sbjct: 24580 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24633

Query: 269   SDVRKEVTNVISKESKLD 286
             SDV ++  N+   E   D
Sbjct: 24634 SDVSRDSVNLTWTEPASD 24651



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P+ K       +  G+ L ++  V   P   I W  +G+ LK T  + + +  +   + I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             ++   +D G Y   A N AG A  +  V V + P                   PPV    
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 17916

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  +         PP      QI  +  +++                   T TW     
Sbjct: 17917 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 17960

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1331
              +  +  +K+   + G++             + +  EN+ G      +  V+      +P
Sbjct: 17961 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18008

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1389
              PP GTP  + I    + + W+    DGG+ +  Y +E  +  +  W +L     + T F
Sbjct: 18009 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18067

Query: 1390  NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                 L    EY+F+V A N+ G  +PS+ SE     +  + P
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18109



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)

Query: 9     SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
             S+ + + SL  + S    +  T A   +  PR++ + EG +A+F     G P P VTW R
Sbjct: 26041 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099

Query: 69    NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
              GQ +++  R  +     + TF   I +V   D G Y+    N  G ++    LT++ + 
Sbjct: 26100 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157

Query: 127   -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
                K +  P   K+   R  +P                       ET+P+       +  
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
               PPK    L     KE  + + +C +        +VTW K    L+ +         +G
Sbjct: 26218 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26275

Query: 215   MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
                L+I+ + + D G Y C +    G +  + +   Q   S +    + ++   SD +  
Sbjct: 26276 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26335

Query: 275   VTNVISK 281
              + V  K
Sbjct: 26336 ESTVTRK 26342



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)

Query: 1249  VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1308
             VR G+++ +  +V G      TW K  K +   + + +       +L I  A +   G Y
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11482

Query: 1309  TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
              +  +N  G  Q    + V+D+P P       +++   + T+SW     +GGS + ++ +
Sbjct: 11483 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11541

Query: 1369  EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1425
             E      K W  +A+  +      +LL ++EY FRV A N  G   P+ E++   +    
Sbjct: 11542 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11600

Query: 1426  -EKPEEPKD 1433
              ++P EP++
Sbjct: 11601 IDRPGEPEN 11609



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)

Query: 1215  GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1269
             G +S+  V + P   P  PP    PP I+    D       SV L     K TG  PIT 
Sbjct: 13664 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13712

Query: 1270  TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               ++F  R  +      K        K+T L    E+   + ++  N  G  +  +    
Sbjct: 13713 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13770

Query: 1328  VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1383
             V   DP  P G P   +I  +S+TL W    YDGG  +  Y +E  D  +K+W +     
Sbjct: 13771 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13830

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1431
                 +F V DL+   +Y+FR+RA N  G  S PS+ +E     ++ E P
Sbjct: 13831 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)

Query: 1302  QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1357
             QE C  Y  +  EN+ G     Q    + V + P PP G     D+  +S++LSW    +
Sbjct: 16601 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16659

Query: 1358  DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             DGGS +  Y +E+    ++ W E A  +S    + +L    EY FRV A+N  G S+P
Sbjct: 16660 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16717



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1271
             S+ TV + P  K P     P   +   +  +V+  E +   G +V G      +  +  W
Sbjct: 15832 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 15890

Query: 1272  MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +K  K        K    E G +     + +   G         +G         V   P
Sbjct: 15891 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 15941

Query: 1332  DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1389
               P G P A  +  +S+TL W   +YDGGS +  Y +E  +     W + +      T F
Sbjct: 15942 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16001

Query: 1390  NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1432
              V  L+ DH Y+FRV A N  G  SEPS+ +   T  ++ + P+
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16045



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L+  +S  P  TI W  + K L+T   + +     L S+ I+ A   + G Y+  
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20449

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G A  + +V + D P              P   +     T    T+  +P P   
Sbjct: 20450 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20496

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
               A +   I++  E  +V                     W         SEH++    E 
Sbjct: 20497 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20526

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
                 T +    E+   + +   NK G  +   + +VV K     P PP G P  + I  +
Sbjct: 20527 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20583

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+ W     DGGS +  Y +E  D  +  W ++   T R T   V  L  + +Y++RV
Sbjct: 20584 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643

Query: 1405  RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1439
              A+N  G    S+ SE     +   P  P  ++ ++D
Sbjct: 20644 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20680



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 33/95 (34%), Positives = 48/95 (50%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P   + I+   V +GS A F  ++ G PDPE  W+K+   I  S      + ED  C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            I DV  +D A    KA+N  GE +  A L+V+  +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1383
            P  P   P   D   SS++L W   + DGGS ++ Y +E+ +     WK        + T
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9266

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
            C     N+++L    +Y+FRV+A+N  G SEPS  +      +  EEP+  +++   D
Sbjct: 9267 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9321



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1383
             + KP PP   P A D   +S+ L+W    +DGGS +  Y +E     ++ W+       +
Sbjct: 10613 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10671

Query: 1384  CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1432
             C  T + V  L     YKFRV A+N  G S+P+   E   V ++ E P+
Sbjct: 10672 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10720



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)

Query: 1006  KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 1063
             K V +S PLS   P   L+     K + TL           L P+  G AK D  + S  
Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12341

Query: 1064  KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1104
             +EE   D   + +  +  +    G  + +K                 E++G   A +Q L
Sbjct: 12342 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12401

Query: 1105  -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
                    + + +  GKKL ++  V   P  T  W      + T+  + + +  S   + I
Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12461

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1215
             +    +D G Y   A+N +G      +V V DAP                   PP  +  
Sbjct: 12462 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12506

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
              ++DA       P     + +   I+   E   V  G+ V     VT T        +  
Sbjct: 12507 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12557

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1335
             K I   E++    +EN              G    L   K+    AQ    V  +P    
Sbjct: 12558 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12602

Query: 1336  GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1388
              T    D     + ++W     DGGS +  Y IE       +W  AN T       RST 
Sbjct: 12603 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12653

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
             +    L+   EY FR+ A+N  G+S PS+ +E  T    P +P  + EV D
Sbjct: 12654 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12703



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)

Query: 45    KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +EG   K+  ++  Y +  QVTW+   + + +  ++ +     G   L +  + + D G 
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25141

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
             Y C+  N  G      EL V+G   +++      +T+  +      +T   +  E PP+F
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25195

Query: 164   ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
                L       G+  RF   IT  P+P VTW K    ++P     + +     G+  L I
Sbjct: 25196 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25255

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             + V  DD   YT +  N  G+ S  A+L++
Sbjct: 25256 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)

Query: 1086 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1143
            D EK+ +     P FK+KL  + +        +C+++   DP   + W  +GK L+    
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1203
            + +  E   CS+    A   D G+  C A N  G    S  + V D    E +   E + 
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760

Query: 1204 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1263
               +  L  +   E  A         T  K    P I+ +PE  +V  GE+     +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820

Query: 1264 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1323
                   W    + I++S+  +V   +    L I+  +    G   +  EN  G  + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879

Query: 1324 NLTVVDKPD 1332
             L +  + D
Sbjct: 1880 KLEIQQRED 1888



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1386
             KP PP   P   DI  SS+ LSW    YDGG  +Q Y +E  D +   W           
Sbjct: 16340 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16398

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             T+  V+ LL  HEY FR+ AIN  G  E +       V EK E P  ++++
Sbjct: 16399 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16449



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/399 (23%), Positives = 152/399 (38%), Gaps = 56/399 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R    I GRP P+VTW K N+ L+  A +  +E     +L I   N+ D G
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14346

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
              +   + N +GK   S  ++++ LD+      +R T  T   V              +TN
Sbjct: 14347 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14404

Query: 278   VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
              I ++   ++     A  K   C+    G S          A N     +P   ++    
Sbjct: 14405 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14464

Query: 326   KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
              ++P       ++  T S+++L      P+P+  G   ++    E +R    +  T  T 
Sbjct: 14465 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQ-WTHITT 14519

Query: 386   QPGLGS-------------QDVVSKAANRRIPMEG-----QRDSAFPKFESKPQSQEV-- 425
               GL               Q +   +A R  P E      +  +  P+ + +   Q++  
Sbjct: 14520 VKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVI 14579

Query: 426   -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
              K    +K    V G PKP V W  +G  + +Q   +     A S  L + +    DSG 
Sbjct: 14580 AKAGDNIKVEIPVLGRPKPTVTW-KKGDQILKQTQRVNFETTATSTILNINECVRSDSGP 14638

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKD 522
             Y  TA N  G++    T+QV  +      P  F  V  D
Sbjct: 14639 YPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSD 14677



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 569
             AP     +KD     G+   L C + G P+P I W   G+ +  +R    + +     L 
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094

Query: 570   IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 628
             +     ED G YTC+A N +G+V  S             S+ LL   P   P  P+  + 
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24141

Query: 629   LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
                +    GS + + V   G P P + W H    +Q SE+   E       L ++ V  +
Sbjct: 24142 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24197

Query: 689   -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
                G Y  +  N  G V   A+L V+      +P   + P  + A L  S +IS
Sbjct: 24198 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24246



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            PP   + L  V V EG+     C I+G P P VTW + +  ++ S    ++ ++G+  L 
Sbjct: 896  PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            I     +D G +TC  VN +G  S S  L++Q     +  F +ET A        VT   
Sbjct: 956  IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003

Query: 280  SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
            + E K  ++S +      + +  Q G   P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1329
            +++      + V +       TI    + H   + ++ +NK G       + +    +  
Sbjct: 9759 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818

Query: 1330 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1383
             P  P   P  S +  +S+T++W    YDGGS V  Y +E+ D+ +K WK +      A 
Sbjct: 9819 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 9877

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                S+ V  L+   +Y+FRV AIN  G    S  S+  T  +    P
Sbjct: 9878 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 9925



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             + V  G+ + +  +V   P   I WT  GK L   K + L Q+     + I++A+  D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
              Y   AKN +G A+ S  V V D P              P  +L     T+ + T+    
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11524

Query: 1227  APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                            + P D                G   IT   +++RK  Q+   +  
Sbjct: 11525 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11555

Query: 1287  ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1340
              +         L A  E+   + +  ENK+G      ++   + +  +D+P  P     A
Sbjct: 11556 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11613

Query: 1341  SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1398
              D   + + L W    YDGGS   SY +E     +  W+ +   + + T + V   + + 
Sbjct: 11614 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11672

Query: 1399  EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
              Y+FRV+  N  G S+  +  E+  V E  ++P  ++++S
Sbjct: 11673 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11711



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1143
            T+  E   +++   P F Q+LQ + V +G ++ LQ +V+  P   + +  +G  ++++  
Sbjct: 90   TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149

Query: 1144 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1194
              +SQEG L S+ I +A PED G Y   A N  G+A  + ++ V   ++ PA +      
Sbjct: 150  FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209

Query: 1195 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1238
              +  E +  R +  +       S ATV+             K  P+ PPK    +  PP
Sbjct: 210  TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269

Query: 1239 QI 1240
             I
Sbjct: 270  SI 271



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 35/96 (36%), Positives = 46/96 (47%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            KP F       + +EG  ARFD K+ G P PE  WF D Q I      ++   EDG  SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            II      D  ++T  A N  G ++ +  L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)

Query: 1308  YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1364
             + ++ EN  G  +       +  +D  DPP G P   +I   ++TL W    Y GG  + 
Sbjct: 14834 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 14892

Query: 1365  SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1421
             SY +E  D  N  W     +      F V  L  D  Y+FRV A N  G  S PS+ S+ 
Sbjct: 14893 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 14952

Query: 1422  TTVGEKPEEPKDEVEVSDDD 1441
              T  +  E PK +V+V   D
Sbjct: 14953 ITCRDDVEAPKIKVDVKFKD 14972



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             PAFK       V  G+ L +       P   + W  +   LK T  +      +   ++I
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15710

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A  ED G Y     N AG+A  +  V V D P                   PP    +
Sbjct: 15711 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15752

Query: 1218  SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
              D  T         PP               K   G S+  +  V      T TW     
Sbjct: 15753 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15794

Query: 1277  QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1331
                         S   ++ TI A R +  GC   + +  EN+ G S       TV   P 
Sbjct: 15795 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15841

Query: 1332  --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1387
                 P GTP  +     S+ + W     DGGS V  Y +E  +  +  W +L       T
Sbjct: 15842 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 15901

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F    L    EY+FRV A N+ G  +PS+ SE   V   P +P    E          +
Sbjct: 15902 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 15960

Query: 1448  DYRTVTINTEQKVSDFYDIEERLGSGKF 1475
              ++  T +   K++ +   ++ L  G++
Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRW 15988



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
             P +K  +  VH  E  K+     +   P  TI W    + L  T  + +       S+S+
Sbjct: 16050 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16106

Query: 1158  EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1217
             + A+  D G Y   AKN AG+   +  V V D P       PE          P V+   
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16149

Query: 1218  SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1275
             S  T +K      PP       II +  +++    E+  L   V     Q ++C      
Sbjct: 16150 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16199

Query: 1276  KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1330
                      KV     G++ T           + ++  NK G  +   +  VV K     
Sbjct: 16200 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16239

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1388
             PD P   P  + +   S+ + W   + DGGS +  Y +E  D     W            
Sbjct: 16240 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16298

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
               V  L+ +H+Y+FRV A N  G SEPS  S
Sbjct: 16299 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16329



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W+K  K   +    K    + G +     + +   G         +G         V   
Sbjct: 18054 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18104

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1388
             P  P G P A  I  +++TL W   +YDGGS +  Y +E  D  +  W +        T 
Sbjct: 18105 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18164

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
             F V  L+ D  Y+FRV A N  G  SEPS  S   T  ++ + P   ++
Sbjct: 18165 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18213



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)

Query: 1321  AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
             AQ+  TV D P    G P  S+I  +S+TL+W     DGGS +Q Y +E  +  +  W +
Sbjct: 21648 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21703

Query: 1381  LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1435
             + + R    T F V  L   +EY+F V A N  G    S  S L    E   P  P   V
Sbjct: 21704 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21763

Query: 1436  EVSDDDEKEPEVDY 1449
             +V+D  +    +++
Sbjct: 21764 KVTDTSKTTVSLEW 21777



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
             P  P   P  +D   SS++L+W    YDGG+ V+ Y +E+ ++A   W    TC      
Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18561

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
             +   F V  L  + EY FR+ AIN  G  EP+         E+ E P+ E++
Sbjct: 18562 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18613



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             +HV  G+ + L   ++  PP    W   G  L+ ++ + +     +  ++I +    D G
Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23310

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1223
              Y    KN  G    + +V + D P                    P+   E DAT   + 
Sbjct: 23311 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23355

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
              +P P+    A +   +++  +  +          G +  ++ +T +  KF +  + +E+
Sbjct: 23356 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23405

Query: 1284  MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             +            + A  +   G Y   +++++   ++ + +     P PP  T    D+
Sbjct: 23406 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23446

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1396
                 +TL+WY    DGGS V  Y +E        W   NK    +   RST      L  
Sbjct: 23447 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23501

Query: 1397  DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1432
               EY+ RV AIN  G+ +PS+ S+     +      KP+ P+
Sbjct: 23502 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23543



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            +E P   P     ++D    EG  ARF C++ G  D +V W+  D+ I+ SR F++   E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
            D    L I++   +D+  YT  A N++G+ + TA L +E  E    E  E+E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1387
             P PPA  P   D   SS++LSW   +YDGGS +  Y +E+  + +  W         + T
Sbjct: 13092 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13150

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
              F V  L+ D +Y+FRV A+N  G S+PS
Sbjct: 13151 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)

Query: 1325  LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
             +   ++P PP       D   SS  L+W    +DGGS +  Y +E+    +  W E    
Sbjct: 22043 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22101

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
             +  +F V+ L+   EY+FRV+A N  G SEP +      + E   EP
Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22148



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 76/349 (21%), Positives = 134/349 (38%), Gaps = 48/349 (13%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P    + +    K  +  +  C++ G P P++ W+  G  +  Q    ++  D  +H L 
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELI-QSRKYKMSSDGRTHTLT 24094

Query: 474   LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             ++     D G Y+C A+N  G++  S  L ++  A  +  P +    K    + G    L
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ--ATPQFHPGYPLKEKYYGAV-GSTLRL 24151

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHI--QDALPEDH-GTYTCLAENAL 589
                  G PVP +TW    + +Q + + T E      H+  ++   + H G Y     N  
Sbjct: 24152 HVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211

Query: 590   GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
             G V     V + +K             P KPT PI ++ L          +  +  +S  
Sbjct: 24212 GTVDAILDVEIQDK-------------PDKPTGPIVIEAL----------LKNSAVISWK 24248

Query: 650   PPPE--VIWLHN----GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY-TCEAWNSAG 702
             PP +    W+ N      E +E  ++         + C      E+ G Y    A N+ G
Sbjct: 24249 PPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFG 24308

Query: 703   ---EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 748
                 +   +V+ ++ P +  +P    KP ++TA        SC +A  P
Sbjct: 24309 ISDPLEVSSVVIIKSPFE--KPGAPGKP-TITAVTKD----SCVVAWKP 24350



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 28    PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
             P++  P  +   ++  +   + AKF  +  G P P   W ++G+ IT GG++ L    +G
Sbjct: 26350 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26408

Query: 88    TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
              F L IH     D G YTC   N +G+   + +LT++
Sbjct: 26409 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1384
             V KP PP G P   D   SS++++W    YDGGS +  Y +EI       W+ +   A  
Sbjct: 15256 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15314

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             ++TS+ +  L  + EYK R+ A+N  G  EP+
Sbjct: 15315 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15346



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
             W K  K +     MKV   + G               Y +  EN  G  +   +   V  
Sbjct: 19136 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19184

Query: 1331  PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1386
              DP  P G P  ++I   S++L W    YDGG+ +  Y +E  +  +  W +      + 
Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19244

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
             T F V +L  D  Y+FRV A N     SEPS+ +    V +  E P+  ++V   D
Sbjct: 19245 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19300



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            EK    P F K + + ++  G  A     + G P P++ WF +   +  S  ++  +D D
Sbjct: 3451 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3510

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
             + SLII     +D+ +YTC A N  G+  C+A L + +  EG  + E E
Sbjct: 3511 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3559



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 117/315 (37%), Gaps = 29/315 (9%)

Query: 405  MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
            ++ + DS     + +P ++   E++ +    EVS         +L+ TPV +   S  V 
Sbjct: 4140 LQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVS 4199

Query: 465  EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA 524
            ++     L   + +  +S + S T   A  ++      + E   + E  P   + L D  
Sbjct: 4200 DEKQDESLKPSEEK-EESSSESGTEEVATVKIQ-----EAEGGLIKEDGPMIHTPLVDTV 4253

Query: 525  VIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDH-GT 580
              EG    L  S+  T    + W    + +   +  +   +     L I     EDH G 
Sbjct: 4254 SEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGE 4311

Query: 581  YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
            Y C A N  G+ + SA +TV                  K  AP+  + +  L+V  G   
Sbjct: 4312 YVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIEPLEVALGHLA 4354

Query: 641  TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              T ++   P     W   G EI ES+           SL I      D G YTC+A N 
Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNE 4414

Query: 701  AGEVRTQAVLTVQEP 715
             G V   A LTV  P
Sbjct: 4415 YGSVSCTATLTVTVP 4429



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)

Query: 1131 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1189
            W     T+K TK  +    EGSL              +++  A+N  GQ++ +    ++D
Sbjct: 7633 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7676

Query: 1190 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1249
            +  +++T           +  PP      D T +       PPK      I ++  ++K 
Sbjct: 7677 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7727

Query: 1250 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
            R G                  W+K  K      + +V +   G+++      +   G   
Sbjct: 7728 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7768

Query: 1310 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1366
                  +G       +  ++ P  P   P     +D     + ++W     +GGS +  Y
Sbjct: 7769 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7822

Query: 1367 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1423
             +E+     + W  + +   +   F V++ ++PD EY  RVRA+N  G SEPS+ SE   
Sbjct: 7823 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 7882

Query: 1424 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1456
              +   +P  ++E  D    E E     V +R V + T
Sbjct: 7883 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 7920



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G+   L+  V   P  TI W    K ++ +    +        + ++ A+  D G Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
                A N AG       V V D P              P      V G  S+    K    
Sbjct: 17200 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17242

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              +PP       I  +  +++    E+  L   V  ++ +T                    
Sbjct: 17243 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17278

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1343
               N  K+T L    E+   + ++  NK G  +   +  V+ K     P PP      ++I
Sbjct: 17279 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17333

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1401
                S+T+ W     DGGS +  Y +E  D +   W +    R T     V  L  DHEY+
Sbjct: 17334 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17393

Query: 1402  FRVRAINVYGTSEPS 1416
             FRV A N  G  EPS
Sbjct: 17394 FRVSAENAAGVGEPS 17408



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 155/774 (20%), Positives = 290/774 (37%), Gaps = 128/774 (16%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E +  +F C ++   +  V W  +G  + +     ++  D   H L +  ++  D G 
Sbjct: 5000 VPERRQARFECVLTR--EANVIWS-KGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV 5056

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+   +  +G+ + +      RL V  +   F S L+D  V EG+     C +    +  
Sbjct: 5057 YT---AEVEGKKTSA------RLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKM-H 5106

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
            + W  N   +  +R+   +   + H  +           + E  L  +S      V E  
Sbjct: 5107 VVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQVKELS 5154

Query: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
            S+ + + L          P F   L D   ++  ++T+  +VS + P  V W  +G EI 
Sbjct: 5155 STAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKDGEEIV 5205

Query: 665  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
             S  +  +  G +  L I++   +D G Y C+     G  +T+A +TV+      +   +
Sbjct: 5206 PSPKYSIKADGLRRILKIKKADLKDKGEYVCD----CGTDKTKANVTVE-----ARLIKV 5256

Query: 725  SKP-RSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNEDVFTLVL 781
             KP   V   +G++      ++    P VH  W   G+ L   +   E++++     L+L
Sbjct: 5257 EKPLYGVEVFVGETAHFEIELSE---PDVHGQWKLKGQPLTA-SPDCEIIEDGKKHILIL 5312

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR---------GREPAS 827
               Q    G+      N     + +V       +   S  +   +          REP +
Sbjct: 5313 HNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKT 5372

Query: 828  CEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTE--- 884
               L G     +  G DR+  ++ G   +    ++    ED    +    +  +HT    
Sbjct: 5373 FRWLKG---TQEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED--KHTSGKL 5425

Query: 885  --EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV 938
              E IR + +  L  +D+  K+    V T  LS D+++      + +  N QR    ++V
Sbjct: 5426 IIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQRLHTTRSV 5477

Query: 939  S-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGS 997
            S ++E K HS   + F+  L+   TS+  V                 +  + KL    G 
Sbjct: 5478 SMQDEGKTHS---ITFKD-LSIDDTSQIRVE-------------AMGMSSEAKLTVLEGD 5520

Query: 998  S--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKP 1055
               + +  +   VE  + +   + S    PV   K  + +KP  NA              
Sbjct: 5521 PYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------------- 5567

Query: 1056 DENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEG 1112
               +K+  K+    LKK +K+D+       GT     + + +       + L  V V E 
Sbjct: 5568 ---IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMET 5624

Query: 1113 KKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            +    + ++S D      W L G+ L  T    + +EG + S+ +     +  G
Sbjct: 5625 ETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTG 5677



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)

Query: 1090  RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1147
             R E      +   K +DV V   G+  +L+  +   P   ++W+ +GK L+ T   + + 
Sbjct: 18202 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18261

Query: 1148  QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
                   ++ ++  +  D G Y     N  G       V V D P              P 
Sbjct: 18262 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18308

Query: 1208  SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
                  V G  ++        P     A +   II+  E  ++                  
Sbjct: 18309 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18350

Query: 1268  TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               +W +   ++Q   +          K+T L    E+   + ++  NK G  +   +  V
Sbjct: 18351 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18396

Query: 1328  VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1381
                   KP  P  TP  S I   S+ ++W     DGG+ ++ Y +E  D     W +   
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18456

Query: 1382  ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
              T       V  L   H Y+FRV A N  G  EPS+ S
Sbjct: 18457 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)

Query: 31    EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
             EAP      +++  K G  A+   ++ G P P + W+R G+ +    ++ +    R T +
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24092

Query: 91    LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
             L +    +ED G YTC ATN  G  + + +L ++ +     G P+  K  G         
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24143

Query: 151   TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
                                     G   R      GRP P +TW  G   LQ S  +++ 
Sbjct: 24144 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24181

Query: 211   EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
                    L +  V  +   G Y   + N  G      ++ IQ   D      V E    N
Sbjct: 24182 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24241

Query: 269   SDV 271
             S V
Sbjct: 24242 SAV 24244



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)

Query: 1329  DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1386
             +KP  P G P  + +   S  ++W   + DGG+ +++Y +E  +     W  + T   R 
Sbjct: 24326 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24384

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
             T F+V++L+   EY+FRV+  N+ G SE S+ SE       P  PK +V +     KE
Sbjct: 24385 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24435



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)

Query: 1098  PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1156
             P FK+ L +    EG+ +  + +VS  PP T+ W  +G+ L     I +  EG    ++ 
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357

Query: 1157  IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1214
             I   LPED G Y+  A N AG   C   + V+      +  K+ E   R  +  +   L 
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25417

Query: 1215  ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1250
                   GTES            +A V  KPA  T   K     +I +  E++K+R
Sbjct: 25418 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25472



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1816
            PYF       ++VEG +  F C++ G P P V W K    +     +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +IS    DD  +YT    N  GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)

Query: 1308  YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + ++ EN+ G       +  V   +PP+  G    +D+  +S +L W    +DGGS V  
Sbjct: 17690 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17749

Query: 1366  YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
             Y +E+     + W  +A  +  +  V  L    EY+FRV+A N  G S+P
Sbjct: 17750 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17799



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)

Query: 1739  EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
             ED  +A L       P    ++P F + + + E  EG +  F+ ++ G P P + W KD 
Sbjct: 25276 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335

Query: 1796  QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
             Q +    + +I ++     +L I D   +D   Y   A N+ G  +C A L VE +   +
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395

Query: 1856  GEGEEEEE 1863
              E + +EE
Sbjct: 25396 QEFKSKEE 25403



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1816
            P   + ++ + V  G  ARF   I G P P++ W+K++Q +  S  F+  +  DG   +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
            ++ +   +D A YTC+A N  G AT +A L VE  E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1384
             V KP PP       D   +S+TL+W    YDGGS +  Y +EI  +  + W+ +      
Sbjct: 17420 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17478

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1442
             R T F +  L    EYK RV A+N  G  E +  S   TV  KPE+  +  E+  D E
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17532



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)

Query: 1302  QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1358
             QE C  Y  +L  N+ G    A+    V V +P  P G     D+  ++ T+ W     D
Sbjct: 18766 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18825

Query: 1359  GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1417
             GGS +  Y +E+    ++ W      ++    +  L    EY FRV A+N  G S+P Q
Sbjct: 18826 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 92/417 (22%), Positives = 146/417 (35%), Gaps = 55/417 (13%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            PA    LQD   +EG+    QC+VS      + W    K +K ++F  ++Q      + I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEMK--------- 1202
             +A PED G Y  VA N  GQ   +  +++ +AP S      E     EMK         
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEMEMKEFSSSFLSA 3416

Query: 1203 -------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
                   +    S +   L   S++ V   P      K    P  I+   +  +  G+  
Sbjct: 3417 EEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVSNADISMGDVA 3474

Query: 1256 ELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENK 1315
             L   V G       W      +  S   K     +   L IL  + E  G YT +  N 
Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3534

Query: 1316 LGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-----------DGGSAVQ 1364
             G       L +  K +    T   S +  S   L      +            G  A+ 
Sbjct: 3535 YGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIF 3594

Query: 1365 SYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEYKFRVRAINVY 1410
             Y++    +   TW    K+L T            S +F V D   +    +  +A N+ 
Sbjct: 3595 EYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 3654

Query: 1411 GTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDF 1463
            G S  + E     E T + + P + K   E  +D  + P        +++EQ+++ F
Sbjct: 3655 GESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATF 3711



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)

Query: 921  EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 978
            E+MD  +  Q+ V+P T  E E K + S ++V + +V ++ K    TPV + V     + 
Sbjct: 4142 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200

Query: 979  P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 1033
                 S+   ++K  + + S + E    K  E+   L   +  GP+   P+ +    E  
Sbjct: 4201 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4258

Query: 1034 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1083
                   + NAK             DE  K    +     V + VN +  H G       
Sbjct: 4259 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4317

Query: 1084 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1138
                 T  + K +  +  AP  K+K++ + VA G      C++ S P     W   G+ +
Sbjct: 4318 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4377

Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
              +    +     + S+ I +    D G Y C A N+ G   C+  +TV   P  E    
Sbjct: 4378 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4436

Query: 1199 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
              +  R+P+     VL     + ++K+P    PK  PK     +    PE    +  E V
Sbjct: 4437 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4492

Query: 1256 EL 1257
            E+
Sbjct: 4493 EV 4494



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             V  G  + +   VS  PP T+ W +N +TL     I  +   S  S+ I+      +G+Y
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10096

Query: 1169  KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
               +AKN+AG+ + +  V V D P    T  P +       S                   
Sbjct: 10097 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10136

Query: 1229  KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1287
                       ++  F PED                G  PIT  ++  +++        V 
Sbjct: 10137 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10170

Query: 1288  NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1341
              +      T+    Q     + +  EN +G      + +A V    +  P+ P       
Sbjct: 10171 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10229

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1399
             ++  +++TL+W    YDGGS + +Y +E      + + ++      S  + V+ L     
Sbjct: 10230 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10289

Query: 1400  YKFRVRAINVYGTSEPS 1416
             Y++RV A+N+ G  +PS
Sbjct: 10290 YEYRVSAVNIVGQGKPS 10306



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + ++  V   P  T+ W    + LK T+ +      +   ++I + +  D G Y   
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
             A+N  G+      + V D P                   PP    + D            
Sbjct: 14643 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14673

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                 +    + F  D     G        V   Q  + TW++    +       +  +  
Sbjct: 14674 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14722

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1346
              ++LT     Q     + +  +N+ G      +  +V       P PP GTP  + +   
Sbjct: 14723 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14776

Query: 1347  SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1404
             S+T+SW+    DGGS +  Y +E  +     W+ +  A      F    L     Y+FRV
Sbjct: 14777 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14836

Query: 1405  RAINVYGTSEPSQESE 1420
              A N+ G S+PS+ SE
Sbjct: 14837 IAENMAGKSKPSKPSE 14852



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)

Query: 1057  ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1115
             E L   ++ E +   KND        A ++   K  + + TA       Q +    G   
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22168

Query: 1116  LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
              +   +S  P   + W L    LK T  + ++      +++++ ++  D G Y    +N 
Sbjct: 22169 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228

Query: 1176  AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1235
             AG    S  V V   P              P +    V    +++ V     PK      
Sbjct: 22229 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275

Query: 1236  MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
             +   I++  E                      T  W      ++ ++           K+
Sbjct: 22276 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22305

Query: 1296  TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1351
             T L    E+   + +  EN+ G S+  +    + + P  P   P   +   + ++++++ 
Sbjct: 22306 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22363

Query: 1352  WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1409
             W    +DGGS +  Y +E  +     W  +    C   ++ V  L+   EY+FR  A+N 
Sbjct: 22364 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423

Query: 1410  YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
              G S+ S+ S    + + P +     EV+D
Sbjct: 22424 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22452



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1387
             P  P   P  +D    S +L+W    YDGG  +  Y +E     ++ W +  T    R T
Sbjct: 14175 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14234

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1447
              F V DL    +Y FR+ AIN  G  EP+   ++  V         E E++ D E + E+
Sbjct: 14235 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14285

Query: 1448  DYRTVTINTEQKVSDFYDIEER 1469
               RT+ +     +  F  I+ R
Sbjct: 14286 -RRTLVVRAGLSIRIFVPIKGR 14306



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)

Query: 1726 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1783
            P      +++E  E ++   A      ++K   KP        + V+EG  ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820

Query: 1784 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
            YP P+V W+ + Q IR+S+ F++ Y  DG   L I D    D  +    A N  G     
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878

Query: 1844 AELIVETMEE 1853
             +L ++  E+
Sbjct: 1879 VKLEIQQRED 1888



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)

Query: 1306  GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1359
             GC   + ++ EN+ G  +       V   + P PP       DI  S+++L+W    +DG
Sbjct: 14437 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14495

Query: 1360  GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1419
             GS +  Y IE     +  W  + T +     V++L    EY F+V A+N  G S P +ES
Sbjct: 14496 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14554

Query: 1420  ELTTVGEKPEEPK 1432
                 V E+   P+
Sbjct: 14555 RPVIVKEQTMLPE 14567



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
            AP F Q LQ V V EG     +  +S  P   + W  +G+ + T+    + +S       
Sbjct: 5    APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            ++I      + G Y   A N +GQA  + ++ V    A                      
Sbjct: 65   LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1274
                                  PP  +Q  +   VR G  V L  +VTG       + + 
Sbjct: 103  ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140

Query: 1275 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
              +IQ S   ++    +   L I  A  E  G Y++   N +G   +   L V  + + P
Sbjct: 141  GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200

Query: 1335 A 1335
            A
Sbjct: 201  A 201



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)

Query: 1754  PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1812
             P   P+F + +R+L V   S A   CK+ G+P P V W++  +  I +   ++I   + G
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                LII+ V  DD   Y  +A N  G  + TA L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P F    R   + EG    F C+I G P PE+ WFK++  I  S +  I    +   SL 
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26695

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
             I +    D  KYT KA N  G+ + TA L+V  + E
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1388
             P PP   P  +D   SS  L W     DGGS V  Y +E  +   + W++      R T 
Sbjct: 9925  PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 9982

Query: 1389  FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
               V  L     YKFRVRA+N+ G  EP + +++  + ++   P  +++ S  D
Sbjct: 9983  LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10035



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1330  KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1386
             KP  P   P   D    +  L W     DGGS +  Y +E        W  +      R 
Sbjct: 11305 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11364

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1441
              +F V  L+  +EY+FR++A N+ G  EP + +E     +    P+ E++V+  D
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)

Query: 1216  TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1268
             TES   + K    K  P    PP++ +  +++        E  G   +TG      +  +
Sbjct: 11885 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 11942

Query: 1269  CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
               W+   K       MKV+N              +H   + +  EN++G  +  +    V
Sbjct: 11943 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991

Query: 1329  DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1378
                DP  P G P      D    S+TL W    YDGG+ +  Y +E+       S ++ W
Sbjct: 11992 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051

Query: 1379  KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             K     A      F V  L  + EY+FRV A N  G   P++  E     E  E P+ ++
Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111

Query: 1436  EVS 1438
             + S
Sbjct: 12112 DAS 12114



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 1342  DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1399
             D+  S++TL+W    YDGGS +  Y +E   +  + W ++ T + T     V  L    +
Sbjct: 23148 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23207

Query: 1400  YKFRVRAINVYGTSEPSQESELTTV 1424
             Y FR+RA N  G SEP +     TV
Sbjct: 23208 YLFRIRAQNEKGVSEPRETVTAVTV 23232



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)

Query: 513   APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 567
             AP F   L++  V    +  L C V G P P + W   G+ I     +Y     + G  +
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I     +D   Y   A N  G VS +A + V                P+K   P  L+
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24535

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 687
             G+  +  + G  V++ +  SG P P + W   G ++ ++   H++   T+    +  VFP
Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24591

Query: 688   -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 734
                  +D G Y   A N  G   +     V  V +P  G +   +S+       +  AS 
Sbjct: 24592 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24651

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKA 760
             G S + +  +         WLR G+A
Sbjct: 24652 GGSKITNYIVEKCATTAERWLRVGQA 24677



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1383
            PDPP        I  +++ LSW     DGGS V  Y +E   WD   +  + W++     
Sbjct: 9515 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9573

Query: 1384 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1431
                 F V+DL+   EY+FRV+A+N  G S+PS      TVG    ++P+ P
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9620



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 163/845 (19%), Positives = 282/845 (33%), Gaps = 134/845 (15%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR--- 101
             + G + K    + G P P + W+++ + + +     L C +  T  L    + + DR   
Sbjct: 20388 RAGTSVKLRAGISGKPAPTIEWYKDDKELQTNA---LVC-VENTTDLASILIKDADRLNS 20443

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             G Y  +  N  G+   T+ + +        G P+  KT+         E    +W     
Sbjct: 20444 GCYELKLRNAMGSASATIRVQILDKPGPP-GGPIEFKTV-------TAEKITLLWRPPAD 20495

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQ-----VTWLKGNVPL------------QPS 204
                 K+   +V++ +  R    +      +        +KGN  +            +P 
Sbjct: 20496 DGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPL 20555

Query: 205   ARVSVSEKNGMQVLEIHGVNQ-DDVGVYTCLVVNGSGKASMSAELS---IQGLDSANRSF 260
                SV  KN        G+ +   +   +  VV     A   +++S   ++  D  +  +
Sbjct: 20556 ESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGW 20615

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
              +  K T  D R++VT +              + + C+    G  P        +P    
Sbjct: 20616 FKVLKETIRDTRQKVTGLTENSDY--------QYRVCAVNAAGQGP------FSEPSEFY 20661

Query: 321   KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--PRAPGLGVLSPSGEERKRPAPPR 378
             K     D P    +  +   T SSITL  ++   +      G  V    GEE +      
Sbjct: 20662 KAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVST 20721

Query: 379   PATFPTRQ-------PGLGSQDVVS--KAANRRIPMEGQRDSAFPKFESKPQ-------- 421
                  T +       PG+     VS    A +  P+E             P+        
Sbjct: 20722 KGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALR 20781

Query: 422   -SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY--EDAGSHYLCLLKAR 478
              S   K  + V+      G P P V W  +     +  GS   Y  E+  S  L  +   
Sbjct: 20782 TSVIAKAGEDVQVLIPFKGRPPPTVTWRKD----EKNLGSDARYSIENTDSSSLLTIPQV 20837

Query: 479   TR-DSGTYSCTASNAQGQLSCSWTLQV---------ERLAVMEVAPSFSSVLKDCAVIEG 528
             TR D+G Y  T  N  G+   S T+ V         ++L V  V+    ++L D  +I+G
Sbjct: 20838 TRNDTGKYILTIENGVGEPKSS-TVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG 20896

Query: 529   QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
                ++   +      + TW +            +       + D   +    +  LAEN 
Sbjct: 20897 GSPIINYVIEKRDATKRTWSVVSH---------KCSSTSFKLIDLSEKTPFFFRVLAENE 20947

Query: 589   LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV-----------MDG 637
             +G                   E   PV  ++  API    + D               DG
Sbjct: 20948 IG--------------IGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDG 20993

Query: 638   SQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 697
               V     V      E  W H G  I ++ +    Q   Q  L  +     + G      
Sbjct: 20994 GSVITEYVVERKGKGEQTWSHAG--ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV- 21050

Query: 698   WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
               + G +  + ++   E      P        VT  +G +V +     G P P++ WL+D
Sbjct: 21051 --TIGPITVKELIITPEVDLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKD 21103

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSAR 817
             G  L K++      + E+  TL +K  +  H G+Y ++L N V  C   V + +      
Sbjct: 21104 GLPL-KESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAV--CRIAVPITVITLGPP 21160

Query: 818   ALPRG 822
             + P+G
Sbjct: 21161 SKPKG 21165



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)

Query: 1308  YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1365
             + +  EN  G  S       T+   P  P GTP   D+   ++TL W     DGGS +  
Sbjct: 21332 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21391

Query: 1366  YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1419
             YSIE     N+ W      +++ C+   + V  L P   Y+FR+ A N  GT S PSQ S
Sbjct: 21392 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447

Query: 1420  ELTTVGEKPEEP 1431
              +    ++   P
Sbjct: 21448 GIIMTRDENVPP 21459



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)

Query: 1746 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            +EAV  +   VKP F + ++++ + EGS      +  G P+P++VW K+   I   ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557

Query: 1806 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
            I  +   G  +L I      D A YT  A+N  G  T   ++ VE +E  E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 90/398 (22%), Positives = 150/398 (37%), Gaps = 53/398 (13%)

Query: 388  GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAW 447
            G+ + +V  K  + R+ + G R     KF S  + Q VKE +T  F CE+S   K  V W
Sbjct: 5055 GVYTAEVEGKKTSARLFVTGIR----LKFMSPLEDQTVKEGETATFVCELSH-EKMHVVW 5109

Query: 448  FLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERL 507
            F     +     ++ +  +  +H L + +    D                        +L
Sbjct: 5110 FKNDAKLHTSR-TVLISSEGKTHKLEMKEVTLDDISQIKAQVKELS---------STAQL 5159

Query: 508  AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYARSTCEAGV 565
             V+E  P F+  L D   +E  +  L+C V    VP + W  +G+ I      S    G+
Sbjct: 5160 KVLEADPYFTVKLHDKTAVEKDEITLKCEV-SKDVP-VKWFKDGEEIVPSPKYSIKADGL 5217

Query: 566  AE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
               L I+ A  +D G Y C      G     A VTV  +           +   KP    
Sbjct: 5218 RRILKIKKADLKDKGEYVC----DCGTDKTKANVTVEARL----------IKVEKP---- 5259

Query: 625  FLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQE 684
                L  ++V  G      +++S  P     W   G  +  S D    + G +H L +  
Sbjct: 5260 ----LYGVEVFVGETAHFEIELS-EPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHN 5314

Query: 685  VFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAI 744
                 TG  + +A N+    ++ A L V+E        FI+    V           C +
Sbjct: 5315 CQLGMTGEVSFQAANA----KSAANLKVKE----LPLIFITPLSDVKVFEKDEAKFECEV 5366

Query: 745  AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 782
            + +P  T  WL+  + +  D   FE++++    ++V+K
Sbjct: 5367 SREP-KTFRWLKGTQEITGD-DRFELIKDGTKHSMVIK 5402



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)

Query: 1100  FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1158
             F+ KL    +  G+   L  + S  P   + W  +    L+  +  I +   +L    I 
Sbjct: 10327 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10382

Query: 1159  KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1218
             KA   D G Y  V +N  G  +  CQV V D P                   PPV     
Sbjct: 10383 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10424

Query: 1219  DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
             D   K        P        I     +K   G+ V +    + +   TC   K  K +
Sbjct: 10425 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10480

Query: 1279  QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1338
             +  +++   ++EN                Y +       S +A+    V D PD P  T 
Sbjct: 10481 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10525

Query: 1339  CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1395
                D    S  ++W    +DGG  + +Y +E  ++ +K W  +        T F V DLL
Sbjct: 10526 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10580

Query: 1396  PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1448
                +Y+FRV A N  G  +PS  S+     +   +P   V     D     VD
Sbjct: 10581 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10633



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QL  PV++K L                   PP F        V  G+  +      GRP
Sbjct: 15636 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15678

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
              P VTW K NVPL+ + RV+        +L I    ++DVG Y   + N +G+A
Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 26/77 (33%), Positives = 44/77 (57%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             V+ GQ  +    I+GRP+P +TW K  +PL+ + R++V++   +  L I   ++DD G Y
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803

Query: 232   TCLVVNGSGKASMSAEL 248
                V N  G+ + S E+
Sbjct: 16804 GITVANVVGQKTASIEI 16820



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 25/72 (34%), Positives = 40/72 (55%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G+  +    + GRP+P ++W+K   PL+ + RV+V E     VL I   N+DD G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885

Query: 232   TCLVVNGSGKAS 243
             T    N +G A+
Sbjct: 17886 TVTATNSAGTAT 17897



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1814
             P F+  + +     G   RF   I  +P+P V W+K  Q I+     + +  + D+ G  
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              L I+ V  DDDA+YT  A N  GE +C A+L V
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)

Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
            +S +  + A L  V    P +K    + I  LEV  G  A+F C+I+  P+    WFK  
Sbjct: 4319 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4374

Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
            + I ES    I   +  + SL I      D  +YTCKA N  G  +CTA L V T+  GE
Sbjct: 4375 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4432



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 84/388 (21%), Positives = 136/388 (35%), Gaps = 87/388 (22%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             ++ G   R    I GRP P+V W K +  ++ +A + V+      VL+   VN+ D G Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16514

Query: 232   TCLVVNGSGKASMSAELSIQGLDSAN-------------------------------RSF 260
             T  + N SG  + SA ++++ LD+ +                                  
Sbjct: 16515 TLTLENSSG--TKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYI 16572

Query: 261   VRETKATNSDVRKEVTNVISKESKLDSLE---------AAAKSKNCSSPQRGGSPPWAAN 311
             V + +AT       VTN      K+D L+          A        P +   P   A 
Sbjct: 16573 VEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 16632

Query: 312   SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGV 363
               PQPP +  ++    +  +   T       S I      +Q +         R   L  
Sbjct: 16633 V-PQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQA 16691

Query: 364   LSPS---GEE---------RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS 411
             +  +   GEE          K  + PR    P     + ++D+V +              
Sbjct: 16692 VITNLTQGEEYLFRVVAVNEKGRSDPRSLAVP-----IVAKDLVIE-------------- 16732

Query: 412   AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
               P  +    S  V+  Q +K    +SG PKP + W  +G P+ +Q   I V +      
Sbjct: 16733 --PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTT 16789

Query: 472   LCLLKARTRDSGTYSCTASNAQGQLSCS 499
             L + +    D G Y  T +N  GQ + S
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTAS 16817



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E  A E    KP     ++D  V   S A+F  K  G P P  +W KD ++I +   +++
Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
               D+ G   L I      D   YTC   NS G  + + +L ++ +++ E +
Sbjct: 26404 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 89/404 (22%), Positives = 153/404 (37%), Gaps = 60/404 (14%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV+ G   R      GRP P++TW +       + +V + +      L I   +++D G
Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17594

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
              Y   + N SG  S SA ++++ LD+         K    +VRK+   ++ +   +D   
Sbjct: 17595 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17646

Query: 290   AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDS-------------------- 328
               AK KN    +R  +    AN   +  + S K+E+  +                     
Sbjct: 17647 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17705

Query: 329   ---------PRTAPQTPVL---QKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKRPA 375
                      P + P    L    +TS+S+  +        R  G  V + P G E K   
Sbjct: 17706 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSI 17764

Query: 376   PPRPATFPTRQPGLGSQDVVS---KAANRR---------IPMEGQRDSAFPKFESKPQSQ 423
                         GL S        KA N +         +P+  +  +  P  +    + 
Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17824

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
              ++  + +K    V G P+P ++W  +G P+ +Q   + V E A S  L + +    D G
Sbjct: 17825 SIQAGEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFG 17883

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
              Y+ TA+N+ G  + + ++ V       V P  F  V  D  VI
Sbjct: 17884 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 17927



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/82 (29%), Positives = 41/82 (50%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +++K G+  R    + GRP P+VTW K  V ++    + +++  G   L +    +D  G
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530

Query: 230   VYTCLVVNGSGKASMSAELSIQ 251
             VYT    N SG A    ++ +Q
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
             P   K ++D+    G AA+  C+I G P P++ W++  + + +SR +++  D   +   +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095

Query: 1818  ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +++   +D+  YTC A N +GE   +++L+++
Sbjct: 24096 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24126



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             PT  +       + V  G  V + + ++G PPP   W   G++++ESE    E       
Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 734
             L I+E    DTG YT E  N  G    T  V+ + +P   T P  I +    S+T S   
Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23358

Query: 735   ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 790
                 G + L    +         WL   +++ + T  F  L   + +   +     +  G
Sbjct: 23359 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23418

Query: 791   QYEILLKNRVGECSCQVSL 809
              Y   L++ V EC   + +
Sbjct: 23419 SY---LQSEVIECRSSIRI 23434



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
            AP FI  P    + EG +  F  +V G P+P V W ++G P+T+G R+ +    + G   
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
            LVI     +D G+YT    N  G    +  L  E  +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)

Query: 1730  LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1789
             ++A+  +   D  Q  +  +A++   + P F        V+ G   + D    G P P V
Sbjct: 15624 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15682

Query: 1790  VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              W KD+  ++++     +  E+ N  L I D C +D   Y  K  NS GEA  T  +IV
Sbjct: 15683 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)

Query: 1224  KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1280
             K   P TP     PP+    P +       SV L     K  G   +T  +++ ++   +
Sbjct: 23818 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 23877

Query: 1281  S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1332
                 H K + +     +T L    E+   + ++ +N +G S  +  +  VV     DKP 
Sbjct: 23878 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 23935

Query: 1333  PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1390
              P      S I   S+TL W     DGG  +  Y +E   S +  WK+      +   F 
Sbjct: 23936 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 23994

Query: 1391  VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1438
             +  LL   EY+FRV A N  G S P     S +++LT+ GE P   K+  +V+
Sbjct: 23995 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24046



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 8/183 (4%)

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             P F+ + ++  V+        C+V+G PKP V W+ +G  +        + E  G ++  
Sbjct: 24431 PHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQL 24490

Query: 474   LLKARTRDSGT-YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
             ++ + T D  T Y   A+N  G +S + +L+VE  A + + P     +     + G+   
Sbjct: 24491 IIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL-PKTLEGMGAVHALRGEVVS 24549

Query: 533   LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP-----EDHGTYTCLAEN 587
             ++    G P P ITW   GQ +       +  V         P     +D G Y   A+N
Sbjct: 24550 IKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKN 24608

Query: 588   ALG 590
               G
Sbjct: 24609 RFG 24611



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)

Query: 171   VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V +EG   ++ CKI    Q  QVTW  G   L+ S +  ++ ++G+ +L +  + + D G
Sbjct: 25081 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25140

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
              Y C VVN  G+ S  AEL ++G+      + R T
Sbjct: 25141 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25175



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)

Query: 1105  QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
             ++ H+  G  L L   +   P   + W    +   T   I ++  GS   + I  A  ED
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10786

Query: 1165  RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
              G+Y    +N AG    S +V V D P              P+      +  +S     K
Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10834

Query: 1225  KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
             +P                         G SV     V      +  W       ++  H 
Sbjct: 10835 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10872

Query: 1285  KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1341
                 +E    L  +AA            EN+ G          +   DP  P G P    
Sbjct: 10873 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 10920

Query: 1342  --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1399
               D+  + ++L W     DGGS +  Y +E  +   + W +  T  +    V  L     
Sbjct: 10921 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 10980

Query: 1400  YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1437
             Y+FRV+A N+ G   P     +    EK   P  E++V
Sbjct: 10981 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11017



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L IK G + + +  V+G P P+VTW ++G  I       +   + G+ SL +     + R
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21529

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
             G YT EA N SG+ +  +++ V+ +  K +G    +   G++ +
Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 27/96 (28%), Positives = 53/96 (55%), Gaps = 1/96 (1%)

Query: 410 DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGS 469
           ++A P F  + QS  V++   V+ +  V+GIP P V ++ +G  + +     ++ ++   
Sbjct: 100 ETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDL 158

Query: 470 HYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE 505
           + L + +A   DSGTYS  A+N+ G+ + +  L V+
Sbjct: 159 YSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)

Query: 1271  WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1327
             W K  K +  + H KV     G               + +  EN  G          +  
Sbjct: 20219 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20267

Query: 1328  VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
             +D  +PP      +DI  +S++LSW   ++DGGS +  Y +E  D  +  W +       
Sbjct: 20268 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20326

Query: 1386  STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1417
              T F +  L  + +Y+FRV A N  G+ S PS+
Sbjct: 20327 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20359



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1385
            +  P PP   P  +D  S+++ L W   +++GG  +  Y ++        W        +
Sbjct: 8503 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8560

Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               + V+++    +YK RV A+N  G   P  E++  TV E  E P  E++VS
Sbjct: 8561 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8612



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)

Query: 1125  PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1183
             PP T+ W  + K L +     +    S   ++I +    D G Y    +N  G+ + S  
Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20861

Query: 1184  QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1238
              V V D PA+      +  SR   + L  PP++   S   +  ++K+ A K         
Sbjct: 20862 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 20913

Query: 1239  QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1298
                                            TW     +   +    ++ SE        
Sbjct: 20914 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 20939

Query: 1299  AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1356
                      + +L EN++G  +       V   + PA     S  D   +S+ LSW    
Sbjct: 20940 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 20990

Query: 1357  YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1416
             +DGGS +  Y +E      +TW      ++    V  L      +FRV A N  G S+P 
Sbjct: 20991 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21050

Query: 1417  QESELTTVGEKPEEPKDEVEVSD 1439
                 + TV E    P  EV++SD
Sbjct: 21051 TIGPI-TVKELIITP--EVDLSD 21070



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)

Query: 1289  SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1343
             SE   K+T L    E+   + ++ EN  G   A     L    +P  P G P     +D 
Sbjct: 21711 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21768

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1401
               ++++L W    +DGG  +  Y IE+  +    W ++    C  T + V DL    EYK
Sbjct: 21769 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21828

Query: 1402  FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
             FRV AIN  G  +  + +      ++   P+ +++ +
Sbjct: 21829 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21865



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 718   GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
             G  P    + + VT  LG++  +SC I G P P + W R GK L + +  +++  +    
Sbjct: 24033 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24091

Query: 778   TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             TL +   +    G Y  +  N VGE      L+LQ
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)

Query: 145  SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
            S P  E +     E P  F     L  + VK G        +TG+P+P++TW K ++ L+
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
               R+++        + I    + D G Y    VN  G+A+   E+++            
Sbjct: 7236 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7295

Query: 253  LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
             D  N S +        D   ++TN + +    DS
Sbjct: 7296 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7330



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1384
            P PP G P        S+ +SW     +GGS +  Y +E  +  +  W  ++        
Sbjct: 9102 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9160

Query: 1385 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1439
             +   FNV  LL   +Y+FR  AIN  G   PS+ S+    G+   P  P    EV D
Sbjct: 9161 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9218



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)

Query: 1112  GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
             G  + L   V   PP  I W+     L+    + +        +  E     D G Y   
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13270

Query: 1172  AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
              +N  G+ E +  V V D P                   PPV  T  + +         P
Sbjct: 13271 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13312

Query: 1232  PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
             P       II +   ++       +   K   T    C+   FR          V N E 
Sbjct: 13313 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13355

Query: 1292  GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1348
             G               + +  EN+ G          V     P G      +RS   SS 
Sbjct: 13356 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13403

Query: 1349  TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1408
             ++ W     DGGS +  Y ++     NK W+ +    S  ++ +DL    EY FRV A N
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13462

Query: 1409  VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1443
               G   P   SE+T V       +D+V   D D K
Sbjct: 13463 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13488



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             S +  +GQ + I   I+G P PT+ W +DG  L K T    V  + D+ TL +K+     
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16799

Query: 789   AGQYEILLKNRVGECSCQVSLM 810
              GQY I + N VG+ +  + ++
Sbjct: 16800 GGQYGITVANVVGQKTASIEIV 16821



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 83/373 (22%), Positives = 138/373 (36%), Gaps = 43/373 (11%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             VV++     R    I GRP+P+V W K    L   A++ V+  +   +L I  V + D G
Sbjct: 18620 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18677

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
              Y   + N SG  S +A ++++ LDS +      +RE K  +          D   ++TN
Sbjct: 18678 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18735

Query: 278   VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
              I ++ +      A  + NC+         Q G S  +   +  +       E+ +    
Sbjct: 18736 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18795

Query: 331   TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
             + P  P  + T   +T   A ++ E        +  G  V   +    K     +  T  
Sbjct: 18796 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18855

Query: 384   TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFP----KFESKPQSQ------EVKENQTV 431
                 GL  G + V   AA         R    P      E KP  +       VK  + +
Sbjct: 18856 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQL 18915

Query: 432   KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
             K      G P+  V W  +G  + ++   + V        L + +A   D GTY    SN
Sbjct: 18916 KIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSN 18974

Query: 492   AQGQLSCSWTLQV 504
             + G ++   T+ V
Sbjct: 18975 SAGSITVPITIIV 18987



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 24/81 (29%), Positives = 40/81 (49%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + VK G        + G+P P V+W K    L+P+  + ++ +  +  LE+  VN+ D G
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              YT    N SG  S + +L +
Sbjct: 12868 DYTITAENSSGSKSATIKLKV 12888



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)

Query: 1131  WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
             W+  GK ++ +    ++   +   ++I+ A  +D G Y   A N  G      +VTV D 
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975

Query: 1191  PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1250
             P                   PP     S+ + +K     TPP       I  +  +++  
Sbjct: 13976 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14015

Query: 1251  AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1310
               E+  L             W    + IQ   H+  +  + G++     +   H G    
Sbjct: 14016 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14056

Query: 1311  LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1368
                   G       + +VD+  P  P   P  S++  ++ T+SW     DGGS +  Y +
Sbjct: 14057 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14111

Query: 1369  EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1426
             E  +  +  W        +     V  L     Y+FRV A N  G   PS+ S+   + +
Sbjct: 14112 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14171

Query: 1427  K--PEEPKDEVEVSDDDEK 1443
                P  P     V+D  +K
Sbjct: 14172 AAYPPGPPSNPHVTDTTKK 14190



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)

Query: 12    ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
             I++T++++ P    S P+T   A  +PPR          L +K G     +  V G P P
Sbjct: 12770 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12828

Query: 63    QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              V+W ++G  +    G +  +    R   +L + +V+ +D G YT  A N SG++  T++
Sbjct: 12829 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885

Query: 121   LTV 123
             L V
Sbjct: 12886 LKV 12888



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)

Query: 1325  LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1382
             +  +D   PP     P  +D   +S++L+W     +GGS V  Y IE+       W +  
Sbjct: 23527 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23584

Query: 1383  TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1436
              C +T   +++    H     EY+FRV A N  G  EP++      V E  E P  E++
Sbjct: 23585 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23642



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 3/97 (3%)

Query: 510   MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVA 566
             + + PS        ++  G+D  ++  V G P P I+W+ +G+P+ Q  R   E  A   
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870

Query: 567   ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
              LHI++   +D G YT  A N+ G  + +  V V EK
Sbjct: 17871 VLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEK 17907



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)

Query: 129   KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             +QLG PV+++          +E +PS+  E P  F T      VK  +  +      GRP
Sbjct: 18883 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 18925

Query: 189   QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
             Q  V W K    L+ + RV+VS    +  L I   +++DVG Y   V N +G  S++  +
Sbjct: 18926 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 18983

Query: 249   SIQGLD 254
             +I  LD
Sbjct: 18984 TIIVLD 18989



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)

Query: 106   CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
             C  TN         ELT +  +  +    V ++   D  S P+  T P I  +   PP+ 
Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19292

Query: 164   ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
                +     +VVK G++ + +  I GRP P ++W K  + ++  AR  +   +   +L +
Sbjct: 19293 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19352

Query: 221   HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + D G Y   + N +G  S++    +
Sbjct: 19353 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)

Query: 1700  AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1759
             AV +  + S M   S +   KS        L++ +  +  ++  A LE  + E+      
Sbjct: 25998 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26057

Query: 1760  FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
                T+        R + V EG +ARF C  +G P P V W +  Q +  S   Q+   + 
Sbjct: 26058 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26116

Query: 1812  GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                +  IS V   D+  Y+    NS G+      L ++
Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1808
            +++   KP+F K +  L +     A F+C++    DP +V  W  D + +  +   ++  
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +E G CSL        D    TC+A N  G    +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)

Query: 1263 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1322
            G  P+T  ++  ++++      KV +     + T+    Q     + +   NK G  +  
Sbjct: 7018 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076

Query: 1323 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
                 VN+ T    PDPP       D  ++S+ L+W     DGGS ++ Y +E     + 
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7135

Query: 1377 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1435
             W         T   V  L     Y +RV+A+N  G S+PS+ +E     +  E P+  +
Sbjct: 7136 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7195

Query: 1436 EV 1437
            +V
Sbjct: 7196 DV 7197



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 82/417 (19%), Positives = 152/417 (36%), Gaps = 61/417 (14%)

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRR-QEGSIEVYEDA------GSHYLCLLKAR 478
            K    ++    + G P P+ +W  +G   +  ++G  ++ EDA       S  + + + +
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDF 531
               +G YS TA N  GQ + +  ++V       + L V ++      +       +G D 
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGD- 9444

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
                 ++G  + + T  ++G+        C  G     + D L E    +   AEN  G 
Sbjct: 9445 ----RIKGYVIEKRT--IDGKAWTKVNPDC--GSTTFVVPDLLSEQQYFFRVRAENRFG- 9495

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
                  V   ++ ++R      P+ P  P           +K+  G     TV +S  PP
Sbjct: 9496 --IGPPVETIQRTTARD-----PIYPPDPP----------IKLKIGLITKNTVHLSWKPP 9538

Query: 652  PE-------------VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
                           + W   G + +     + ++   +    ++++       +  +A 
Sbjct: 9539 KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCN-KRDVEELQFTVEDLVEGGEYEFRVKAV 9597

Query: 699  NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-- 756
            N+AG  +  A +   +      P  I     +    G +V I   I G PFPT+ W +  
Sbjct: 9598 NAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAP 9657

Query: 757  ----DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
                D K       H   L  +D  TLV+ + +    G Y I   N +G  S ++ L
Sbjct: 9658 PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRL 9714



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)

Query: 575   PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 630
             P D   +  +A NA+G +S            S+ S  ++     V P     P +  GL 
Sbjct: 21423 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21472

Query: 631   DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
                +  G  + +   V G P P V W  +G EI++  +          SL +++   +  
Sbjct: 21473 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21529

Query: 691   GTYTCEAWNSAGEVRTQAVLTVQE 714
             G YT EA N++G  + +  + VQ+
Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQD 21553



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1385
            +++P PP     +SD   SS+ L W     DGGS +  Y IE  +     W    +    
Sbjct: 6792 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6850

Query: 1386 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
              ++ V  L   ++Y +RV A N  G S+PS+     T  +   EP  ++    D
Sbjct: 6851 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 6905



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)

Query: 574   LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 632
             +P++  T T L E A  Q    A   V+    S  S+ +  +A +  P   + +   S L
Sbjct: 12749 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12808

Query: 633   KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 689
              V  G+ V +   V G P P V W  +G  ++ +E     +   Q +LC  E+F    +D
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12865

Query: 690   TGTYTCEAWNSAG 702
             +G YT  A NS+G
Sbjct: 12866 SGDYTITAENSSG 12878



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 25/82 (30%), Positives = 36/82 (43%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             + KE    R    I G+P P V+W KG  PL    RVSV        L ++   + D G 
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555

Query: 231   YTCLVVNGSGKASMSAELSIQG 252
             YT  + N +G    +  + + G
Sbjct: 13556 YTITLKNVAGTKEGTISIKVVG 13577



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)

Query: 29    LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
             LT  P+  LP     I+ G   K E  V G P P ++W ++G+P+    R  ++     T
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870

Query: 89    FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               L I   +++D GKYT  ATN +G     + + V
Sbjct: 17871 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
             NA    S    S   +    E  P +  +  +    L +  G + R    ++G P P V 
Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21494

Query: 1791  WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             WFKD   I +  + +I  D  G+ SL + D   D    YT +A N+ G A    ++ V+
Sbjct: 21495 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 173/894 (19%), Positives = 314/894 (35%), Gaps = 157/894 (17%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
             I+ G+    +  V G PEP++ W +  + +    +  L   G R T   VI      D G
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22619

Query: 103   KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
             KYT    N SG + V+V + V  S     G+  VS+   ++    +S P  +    I   
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22678

Query: 159   CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
                +  T     V+ EG+    S  +T   +      +V  +    P  P     +  +N
Sbjct: 22679 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22738

Query: 214   GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
                +    G+ ++   G    ++     ++    E+S   +D   +  +R T+       
Sbjct: 22739 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22798

Query: 270   -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
              D R +VT+++               + C    R  +   A NS+P     S   SC++ 
Sbjct: 22799 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22841

Query: 328   ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
                  P +AP+  V+  T  SI+L   +   +     +G +    E+           A 
Sbjct: 22842 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 22899

Query: 377   PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP---------------- 420
              R   F      +G +     AA   + ++G  + +    E +P                
Sbjct: 22900 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSEYSESIAEIEPVERIEIPDLELADDLK 22956

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL-KART 479
             ++  ++   +++    VSG P P + W  +G  +     S  + +   S+ L ++ K   
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL----ASRAIIDTTESYSLLIVDKVNR 23012

Query: 480   RDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
              D+G Y+  A N  G+ S +  ++V         + V EV+    ++  +   I+G    
Sbjct: 23013 YDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDG---- 23068

Query: 533   LQCSVRGTPVPR-ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG- 590
                   G PV   I          +   T +       I   +      +  L EN  G 
Sbjct: 23069 ------GAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGI 23122

Query: 591   --QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
                   S  V V E          +P+ P+K            L+V+D ++ T+T  ++ 
Sbjct: 23123 GEPCETSDAVLVSE----------VPLVPAK------------LEVVDVTKSTVT--LAW 23158

Query: 649   NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---EDTGTYTCEAWNSAGEVR 705
               P     L++G            + GT+  + +  + P   E T T   E       +R
Sbjct: 23159 EKP-----LYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIR 23213

Query: 706   TQAVLTVQEPHDGTQPWFISKPR-------------SVTASLGQSVLISCAIAGDPFPTV 752
              Q    V EP +      +   R             ++    G+ V +   IAG P P  
Sbjct: 23214 AQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAA 23273

Query: 753   HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              W   G  L +++    V  +  V  L +++      G+Y + LKN  G  S  + +++ 
Sbjct: 23274 SWFFAGSKL-RESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIIL 23332

Query: 813   NS-------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 853
             +               A ++    EP   +    GG    G   ++  + RPGW
Sbjct: 23333 DKPGPPTGPIKIDEIDATSITISWEPPELD----GGAPLSGYVVEQRDAHRPGW 23382



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1387
             P PP G P         + + W     DGG+ + +Y ++  +  +  W  +        T
Sbjct: 22743 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22801

Query: 1388  SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1431
                V  L+   +Y+FRV A+N  G SEPS+ S   +  E    P
Sbjct: 22802 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22845



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
             V +   S  S++   ++P     +P  E    +   + + I+ GA+ +    V G P P 
Sbjct: 22923 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 22980

Query: 64    VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             +TW + G  + S  R ++D        L++  V+  D GKYT EA N SG +  TV + V
Sbjct: 22981 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23037



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)

Query: 988  KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 1045
            ++++ + +GS   E +    VES   +S  + S       V         K + +A  ++
Sbjct: 4141 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200

Query: 1046 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1105
              K   + KP E  + +S E   ++V   V  +    G    +         P     L 
Sbjct: 4201 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4250

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1164
            D    EG  + L   +++     + W    K + + +     Q+ +  ++ I+K   ED 
Sbjct: 4251 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4308

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
            +G Y C A ND+G+   S ++TV                                    K
Sbjct: 4309 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4333

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
            + AP    K           E  +V  G   +   ++     +   W K  ++I ES+  
Sbjct: 4334 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4383

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             + +S+  S L IL  +   CG YT    N+ GS      LTV
Sbjct: 4384 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)

Query: 752  VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 810
            V+W  + K +  D   F+ LQ+++ +TLV+ KV    H G+Y     N  G+ +    L 
Sbjct: 4272 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4330

Query: 811  LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 870
            +   +A  + R  EP    ++  G +           ++R  W   G+  + E D   +R
Sbjct: 4331 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4386

Query: 871  G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 917
                     +L+ +V +  ++T +A  +         L      G+K   K L E   K 
Sbjct: 4387 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4444

Query: 918  IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 963
             P E++  ++ L++   + +PK   ++  KV  P           ++V+  +V  ++   
Sbjct: 4445 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4502

Query: 964  KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 1023
            K P P KVP  KPA P           LPA       E   A+      P    +P+   
Sbjct: 4503 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4548

Query: 1024 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1083
             PV    P    K    A   E  KP G   P + +   +   ++ + +       G   
Sbjct: 4549 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4603

Query: 1084 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1137
              +     + +     F ++++D+ + E    G   + +C VS   P+T I  W  +G  
Sbjct: 4604 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4660

Query: 1138 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
            ++ +   +FI   ++  L  + ++ +   D G Y CV +    +   + ++ V++ P
Sbjct: 4661 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4714



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)

Query: 1111  EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
             EG  +   C++ + D    + W    + L+ ++   ++ E  +  + ++     D G Y+
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143

Query: 1170  CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1228
             C   ND G+     ++ V         +  +   RR               T+KK K   
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25183

Query: 1229  KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1285
              T      PP+      ++    GE+V     +T       TW K  ++I+  ++ K   
Sbjct: 25184 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25243

Query: 1286  VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1334
              E+ +   +LTI +   +    YT++  NK G    +  LTV   P P            
Sbjct: 25244 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25303

Query: 1335  -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1384
                     G     +IR S +   TL W     DG       +IEI       +      
Sbjct: 25304 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25354

Query: 1385  RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1444
                + +++D LP+    +RV A N  G++      ++  +  K +E K + E     +K+
Sbjct: 25355 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25411

Query: 1445  PEVDYRTVTI 1454
              +   R   I
Sbjct: 25412 IDKTLRMAEI 25421



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F+   + +   +G  A FE  V G P P VTW +  + + +   + +     G+ + +
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
            ++    ED G Y C+A N  G      EL V          P  +K+  +          
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3694

Query: 145  SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
              PAVE   S       + AT +   ++K   +   + +++     +   L   +PL   
Sbjct: 3695 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3749

Query: 205  ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
               S+ E++ +          +    + C  +NGS         S  L +Q + S  ++F
Sbjct: 3750 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3798

Query: 261  VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
             +         ET+A  SD  K   + +S E +++SL         + P+ G  P     
Sbjct: 3799 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3852

Query: 312  SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
            S  +PP  S L S  +    +P+   +  T+    +TLQ    Q
Sbjct: 3853 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 3895



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 37/120 (30%), Positives = 50/120 (41%), Gaps = 11/120 (9%)

Query: 388   GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPE 444
             GLG  D         IP+E Q     P  E   +  E   VK   TV+F   + G+P P 
Sbjct: 10992 GLGLPDTT-------IPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPT 11044

Query: 445   VAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV 504
               W  +G+ ++  E    V  D  S  L +     RD+G Y  T SNA G  + +  L V
Sbjct: 11045 AKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             LP      KE +  + +  ++G P P V+W +   P+ +  R  ++     T +L+++  
Sbjct: 13490 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13548

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTVEG 125
              + D GKYT    N +G ++ T+ + V G
Sbjct: 13549 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13577



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)

Query: 1717  SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1771
             S ++  +  P+ P      E++    E V    + A  +    +K   SK I  L  VVE
Sbjct: 26184 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26243

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
              S  R           EV W+KD + ++E+ HFQ  Y  DG   L I+++   D  +Y C
Sbjct: 26244 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26294

Query: 1832  K 1832
             +
Sbjct: 26295 E 26295



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L+DV+V EG K +L+C+VS     ++ W LN + +K    +    +G+   + I +    
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD 1188
            D G YK +     G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            PHV+  F + + DL+V E   ARF+C++    + +V WFKD   I++ + + I   +   
Sbjct: 5875 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 5930

Query: 1814 CSLIISDVCGDDDAKYTCK 1832
              L+I+    DD+A+Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 565
             ++E  P +   L    +  G+   ++  V+G PVPR+TW  +G  I+   +   T   G 
Sbjct: 21460 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21516

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 602
               L ++DA  +  G YT  A+NA G       V V +
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)

Query: 1752 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1811
            E  H++  F K I+D++V+E   A F+C++   PD  V W KDDQ ++ +   +I  ++ 
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             +  L+I      D  KYT  A    G    TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 97/438 (22%), Positives = 161/438 (36%), Gaps = 66/438 (15%)

Query: 115  RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
            RQ TV+   EG+  K     V +   G     P  ET+P    E     A +L     G 
Sbjct: 8562 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8616

Query: 170  VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
            + +  G+  R    +TGRP P   W K    L    RV +        L I    + D G
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8675

Query: 230  VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
             Y     N  G    +A           L ++ + +  +  +        D   E+T  I
Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8735

Query: 280  --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
               K++K+ +    +E      + +    G    +   ++ +    PP E       D  
Sbjct: 8736 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8795

Query: 328  SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
             P T+P+     ++T S+ITL       EPR+ G   +     E++R   P         
Sbjct: 8796 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8851

Query: 382  FPTRQPGLGSQDVVS------KAANR------RIPMEG--QRDSAFP----KFESKPQSQ 423
             PT    + + D         KA N        +P+    Q D   P    +   +  + 
Sbjct: 8852 CPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTI 8911

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH-----YLCLLKAR 478
            +VK  + V    +V+G+P P++ W    T + +   ++++ ++  S       L + KA 
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971

Query: 479  TRDSGTYSCTASNAQGQL 496
              D GTY+ TASN  G +
Sbjct: 8972 REDKGTYTVTASNRLGSV 8989



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 30/144 (20%)

Query: 511   EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAE 567
             +V P+FSS     +V  GQD  ++  + G P P ITW  +G P++       T    +  
Sbjct: 16734 DVKPAFSSY----SVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTT 16789

Query: 568   LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 627
             L I++   +D G Y     N +GQ + S  +   +K             P  P  P+   
Sbjct: 16790 LSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFD 16836

Query: 628   GLSDLKVMDGSQVTMTVQVSGNPP 651
              +S            ++ +S NPP
Sbjct: 16837 DVS----------AESITLSWNPP 16850



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             +  G  + + + V G P P + W+ +G  ++++   + E+  T   L I+E   +D G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885

Query: 694   TCEAWNSAG-EVRTQAVLTVQEP 715
             T  A NSAG      +V+ +++P
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKP 17908



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 168/821 (20%), Positives = 276/821 (33%), Gaps = 127/821 (15%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             +K G   + E  V G P P + W ++G+ +    +  +      T +LV       D G 
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15034

Query: 104   YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG---DRFSAPAVETRPSIWGECP 160
             YT  ATN              G FAK +    V    G      +   V +   +    P
Sbjct: 15035 YTLTATN-------------PGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFP 15081

Query: 161   P--KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA---RVSVSEKNGM 215
             P      K+   +V++ +  R +       + QVT LK    L+ +    RV    K G+
Sbjct: 15082 PLDDGGAKIDHYIVQKRETSRLAWTNVA-SEVQVTKLKVTKLLKGNEYIFRVMAVNKYGV 15140

Query: 216   -------QVLEIHGVNQDDV------------GVYTCLVVNGSGKASMSAELSIQGLDSA 256
                     VL ++     D              +  C     S   S      ++  D A
Sbjct: 15141 GEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKA 15200

Query: 257   NRSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
              + +++  K T +D+R +V+ +    E +   +   A   +  SP            +P 
Sbjct: 15201 GQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPG 15260

Query: 316   PPRESK-LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE--------PRAPGLGVLSP 366
             PP   + L++ + S   A   P+    S           PE        P A GL   S 
Sbjct: 15261 PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPA-GLKATSY 15319

Query: 367   SGEERKRPAPPRPATFPTRQPGLGSQDVV---SKAANRRIPMEGQRDSAFPKFESKPQSQ 423
             +          +   +     GLG   +V    KA +R +P E + D+   K  +     
Sbjct: 15320 TITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVT----- 15374

Query: 424   EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR--D 481
              ++   T++    + G P PEV W  +       E   +   ++ S Y  L+       D
Sbjct: 15375 -IRACCTLRLFVPIKGRPAPEVKWARD-----HGESLDKASIESTSSYTLLIVGNVNRFD 15428

Query: 482   SGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
             SG Y  T  N+ G  S    ++V       + L V EV  +  ++  D  +++G   +  
Sbjct: 15429 SGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKN 15488

Query: 535   CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTY-TCLAENALGQVS 593
               V      R       +      + C     ++   D L E    Y   LAEN  G + 
Sbjct: 15489 YIVEKRESTR-------KAYSTVATNCHKTSWKV---DQLQEGCSYYFRVLAENEYG-IG 15537

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               A      K S R      P+ P K T            +MD ++   +V +S   P  
Sbjct: 15538 LPAETAESVKASER------PLPPGKIT------------LMDVTR--NSVSLSWEKPE- 15576

Query: 654   VIWLHNGNEIQESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                 H+G           + +G+ + + C      E T T   +    +  V  Q    +
Sbjct: 15577 ----HDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGI 15632

Query: 713   QEPHDGTQPWFISKP-----------RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              +P   + P  I+K             + T   G+ + +     G P P V W +D   L
Sbjct: 15633 SDPRQLSVP-VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPL 15691

Query: 762   CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
              K T        E+   L +K       G Y + L N  GE
Sbjct: 15692 -KQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGE 15731



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)

Query: 1228  PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1284
             P  PP A   P++     +   +R  E         G   I   W+  K R  I   +  
Sbjct: 22340 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22394

Query: 1285  KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             KV   E   K+T L    E+    Y L       + +A   +   +  D P G P  +D+
Sbjct: 22395 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22453

Query: 1344  RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1398
               S+++L W   +YDGGS V  Y IE   + +  +  W +          F V  L    
Sbjct: 22454 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22513

Query: 1399  EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1436
              Y+FRV A N  G  S+ S+ +   T  ++   PK E++
Sbjct: 22514 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22552



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)

Query: 656  WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            W+ +G+ I+ES    F   G    L I +V   D G YTC       E  + A L V+E 
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713

Query: 716  HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
                  +  +    VT   GQ + +SC +  +    V W +DGK + +  G         
Sbjct: 4714 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 4768

Query: 776  VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 810
            +  L +       AG Y + ++N    ECS  V ++
Sbjct: 4769 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 4804



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1386
             P  P G P   D+  S+++L W    +DGGS +  Y +E        W    T       
Sbjct: 12692 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12751

Query: 1387  TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1438
               +    L    +Y+FR  A      S PS+ S+  T+  +   P+ ++ V+
Sbjct: 12752 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12803



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
             L +K G T +F   +RG P P   W  +G  I +   + ++      FS  L I      
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11079

Query: 100   DRGKYTCEATNGSGARQVTVELTV 123
             D G+Y    +N +G++ V V LTV
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)

Query: 601   HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
             +EK  S   +  +PV A      P F    +   V+ G  + + V   G P P V W  +
Sbjct: 15628 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15687

Query: 660   GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 718
                ++++   + E       L I++   ED G Y  +  NSAGE + T  V+ + +P   
Sbjct: 15688 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15747

Query: 719   TQP 721
             T P
Sbjct: 15748 TGP 15750



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 81/381 (21%), Positives = 132/381 (34%), Gaps = 74/381 (19%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V+V+ G   R    + GRP P+VTW K  +      +  V   + M  L I    +DD G
Sbjct: 12119 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12177

Query: 230   VYTCLVVNGSGKASMSAELSIQG----LDSANRSFVRETKA------TNSDVRKEVTNVI 279
              Y+  +VN +G+ ++   + +      +     S V +T          +D   +VT+ I
Sbjct: 12178 KYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYI 12237

Query: 280   SKESKLDSLE----------------------------AAAKSKNCSSPQRGGSPPWAAN 311
              ++ + D                                A        P     P  A++
Sbjct: 12238 VEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 12297

Query: 312   --SQPQPPRESKLESCKDSPRTAPQTPVLQ----KTSSSITLQAARVQPEPRAPGLGVLS 365
               S+P PPR+ ++     +  T    P L+    K    IT      QP  R     V+ 
Sbjct: 12298 PLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVK 12357

Query: 366   ---------PSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF 413
                        G++ K     R A   + P    G      V +A  + +P         
Sbjct: 12358 DLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEG------VYEAKEQLLP--------- 12402

Query: 414   PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
             PK    P+   +K  + ++    V G P P   W  +G         + V++   S  L 
Sbjct: 12403 PKI-LMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSSSILI 12460

Query: 474   LLKARTRDSGTYSCTASNAQG 494
             +     +DSG YS TA N+ G
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 160   PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
             PPK      ++ +K G+  R    + G+P P   W KG   +  S+ ++V + +   +L 
Sbjct: 12402 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12460

Query: 220   IHGVNQDDVGVYTCLVVNGSG 240
             I  V + D G Y+    N SG
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)

Query: 4    VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
            VK V ++ +SK S +V P    R D  P  +   F+       ++EG       +++G P
Sbjct: 9594 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9647

Query: 61   EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
             P +TW +       N +P+   T   + ++D     T +LVI      D G YT  A N
Sbjct: 9648 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9703

Query: 111  GSGARQVTVELTVEG 125
              G     + L V G
Sbjct: 9704 NLGTASKEMRLNVLG 9718



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)

Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            + +KT++++EV E   A F+C++  +  P  +W K+   I  S  F+I      +  LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
             +   +D A+YT    N    AT T   I+ T    +   EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1819
            +EV EG+      KI+G P P + WFK      +++   + YD        D  C+L+I 
Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9687

Query: 1820 DVCGDDDAKYTCKAVNSLGEAT 1841
                 D   YT  AVN+LG A+
Sbjct: 9688 QSRRSDTGLYTITAVNNLGTAS 9709



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V+ GQ  R   ++ GRP+P +TW K    L    RV + +      L+I    + D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
              Y     N SG A  SA +++  LD       +  K TN  V KE    IS E+ LD+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11531



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)

Query: 1747  EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
             E V E K  + P        + +  G   R +  + G P P   W K +  +  S H  +
Sbjct: 12391 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450

Query: 1807  DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              +  D +  LII DV   D   Y+  A NS G  T   +++V
Sbjct: 12451 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 1731  NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1787
             NA  + SE   S   + A  E  P    + P +  TI    V  G + + D  I G P P
Sbjct: 16020 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16076

Query: 1788  EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
              + W K DQ +  +   +I    D   SL + D    D   Y  KA N  GE + T  + 
Sbjct: 16077 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135

Query: 1848  V 1848
             V
Sbjct: 16136 V 16136



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1331  PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1390
             P PP      S +   S+TL W     DGGS +  Y IE  +  +  W  +         
Sbjct: 19486 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19544

Query: 1391  VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1421
             V+   L    EY++RV A N  G S PS+ S L
Sbjct: 19545 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19577



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)

Query: 1094 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1150
            +G    F ++LQD+ V E     L+C VS   P  I   W  N   LK+  K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
               +++++    ED+G Y  V                                       
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293

Query: 1211 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1270
              + G ++   +K KP P           I+Q   DQKV  G+ V+L  KV+  + +   
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341

Query: 1271 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
            WMK  +++Q S+ + +   +    L I    +E  G Y+  +     S   +V++  VD 
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401

Query: 1331 PDP 1333
              P
Sbjct: 2402 ITP 2404



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)

Query: 1760 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1813
            F K I+D+ + E    GS+A F+C +   P   +  W KD  +IRES +H  I   +D  
Sbjct: 4620 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +I  DV   D  +YTC       E T TA+L+VE +
Sbjct: 4678 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)

Query: 117   VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
             +  + TV G    Q  +  V++K      S P+  T P    +          PKF    
Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17137

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
               +VV  G+  R    + G+P P + WL+G+  ++ SAR  +   +   +L +    + D
Sbjct: 17138 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17195

Query: 228   VGVYTCLVVNGSGKASMSAELSI 250
              G Y     N +G  S    + +
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKV 17218



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)

Query: 1059 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1107
            +KS  K +++ K + + +N +  H G   +      + T+ A          F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021

Query: 1108 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1167
             V E K+ + +C+VS +P  T+ W  + + L+ T  I + +E  +  + I      D G 
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080

Query: 1168 YKCVAKNDAGQAE 1180
            Y  VA  +   A+
Sbjct: 3081 YTVVAGGNVSTAK 3093



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 172   VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
             +K G   R S  I G P P+VTW K +      AR+ V+       LEI     +D G+Y
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10790

Query: 232   TCLVVNGSGKASMSAELSI 250
             +  V N +G  ++S ++ +
Sbjct: 10791 SLTVENPAGSKTVSVKVLV 10809



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 21/72 (29%), Positives = 34/72 (47%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++++ G   R    + GRP P++TW K NV L+    + +   +    L    VN+ D G
Sbjct: 13206 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13265

Query: 230   VYTCLVVNGSGK 241
              Y   + N  GK
Sbjct: 13266 KYILTLENSCGK 13277



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + + + V G P P V W      +++++  +FE   T   L I E    D+G Y   
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642

Query: 697   AWNSAGEVRTQAVLTVQ 713
             A N  GEV    V+T+Q
Sbjct: 14643 ARNIVGEVGD--VITIQ 14657



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 576
             KD  V+  G+ F +   + G P+P I W+   Q +   AR   ++      L ++DA+  
Sbjct: 16053 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16112

Query: 577   DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 633
             D G Y   A+N  G+ S    VTV+ K   R         P  P  P+ + G++  K   
Sbjct: 16113 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16159

Query: 634   -----VMDGSQVTMTVQVSGNPPPEVIW 656
                  + DG    +   V       ++W
Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVW 16187



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)

Query: 1753  KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
             +P VKP FS       V  G   + +  I G P P + W KD   ++++    +  D   
Sbjct: 16732 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16786

Query: 1813  NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1847
               +L I +   DD  +Y     N +G+ T + E++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16821



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)

Query: 736   QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 795
             + + I     G P  TV+W +DG+ L K+T    V  ++ V +L +K+      G YE+ 
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 18971

Query: 796   LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
             + N  G  +  +++++ +      P   +  SC+ +
Sbjct: 18972 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19007



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1158
            F + L+D  V EG   +L+C+VS +  A + W  NG + LK+ K+ I++ +G +  + I 
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5847

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
               PED   Y C    DA   + SC + V
Sbjct: 5848 DCTPEDIKTYTC----DAKDFKTSCNLNV 5872



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            L E   F     N+ + E  T K    V   P  +V W++  + I   GR+ +    R  
Sbjct: 5962 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6020

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              LVI   H ED G Y C   +     +V V                             
Sbjct: 6021 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6051

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
                     E   +F +K   + + EG+   F C I+    P V W + +  L+   +  
Sbjct: 6052 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6101

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            V      +VL +      D+G Y  +V    G A  +A L++
Sbjct: 6102 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6139



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 27/87 (31%), Positives = 38/87 (43%), Gaps = 9/87 (10%)

Query: 528  GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA---------GVAELHIQDALPEDH 578
            G+   +   V G P+P+I W  N   I+      +             EL I  A+ ED 
Sbjct: 8916 GEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDK 8975

Query: 579  GTYTCLAENALGQVSCSAWVTVHEKKS 605
            GTYT  A N LG V  +  V V+++ S
Sbjct: 8976 GTYTVTASNRLGSVFRNVHVEVYDRPS 9002



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/93 (27%), Positives = 39/93 (41%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P+  + ++ +  L V  G+ V     + G P P   W  +G+EI+  E +  E       
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11070

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
             L I+     DTG Y     N+AG       LTV
Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 80/404 (19%), Positives = 147/404 (36%), Gaps = 56/404 (13%)

Query: 437   VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
             V G P P+V W   G     ++G +++ +     +L +  +   DSG YS T  N  G+ 
Sbjct: 12133 VRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMA--FLVIPNSTRDDSGKYSLTLVNPAGEK 12190

Query: 497   SCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             +    ++V         L V +V  +   V       +G   V    V      R TW  
Sbjct: 12191 AVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW-- 12248

Query: 550   NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
                    +  T E      H+ + +P +   +   A N  G       V     K    S
Sbjct: 12249 -------STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLAS 12296

Query: 610   EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES--- 666
             + L     S+P  P         + ++ +++T         PP    L +G    +    
Sbjct: 12297 DPL-----SEPDPP---------RKLEVTEMTKNSATLAWLPP----LRDGGAKIDGYIT 12338

Query: 667   ---EDFHFEQRGTQHSLCIQEVFPEDTGT-------YTCEAWNSAGEVRTQAVLTVQEPH 716
                E+     R T++S+ ++++    TG        +   A N+ G    +    V E  
Sbjct: 12339 SYREEEQPADRWTEYSV-VKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAK 12397

Query: 717   DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
             +   P  I  P  +T   G+ + I   + G P PT  W + G+     + H  V + +  
Sbjct: 12398 EQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-KKGEDEVVTSSHLAVHKADSS 12456

Query: 777   FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
               L++K V    +G Y +  +N  G  + ++ +++ ++     P
Sbjct: 12457 SILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQP 12500



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T   G +V +   + G P PTV W +DG  L K     ++    ++ TL L  V    +
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866

Query: 790   GQYEILLKNRVGECSCQVSL 809
             G Y I  +N  G  S  + L
Sbjct: 12867 GDYTITAENSSGSKSATIKL 12886



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)

Query: 171   VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             VV+ G   R      GRP P   W K +  L  S R  +   +    L +   N++D G 
Sbjct: 21871 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 21928

Query: 231   YTCLVVNGSGKASMSAELSI 250
             YT  V N SG  S++  + +
Sbjct: 21929 YTLTVENNSGSKSITFTVKV 21948



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 639
             +  LA+NA G +S  +  T      + + EY    AP K      L G  DL  +  GS 
Sbjct: 22517 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22567

Query: 640   VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             + +   V G P P++IW     E+   E    +  G + +  I+     D+G YT    N
Sbjct: 22568 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22627

Query: 700   SAGEVRTQAVLTVQEPHDGTQP 721
             ++G   T+AV  + +  D   P
Sbjct: 22628 ASG---TKAVSVMVKVLDSPGP 22646



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)

Query: 139   TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             T  D ++ P  E    + G+           V ++ G        + G+P+P++ W KG+
Sbjct: 22539 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22588

Query: 199   VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
               L    +VS+          I   ++ D G YT  V N SG  ++S  + +  LDS
Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22643



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 63/277 (22%), Positives = 106/277 (38%), Gaps = 59/277 (21%)

Query: 40   RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
            +N+ + E  TA FE  V  +  P + W +NG  I    +F +   ++G    L+I     
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899

Query: 99   EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
            ED  +YT    N   +  +TV                      E+TV  EG   K L   
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959

Query: 135  VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
            V  K+                      GD     F A    +  +++ E    +F   + 
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019

Query: 169  RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             + V E +   F C+++  P   V W+K +  LQ + R+ + ++  +  L I      D 
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078

Query: 229  GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            G YT +    +G    +A+L ++G D   RS  +E +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRSIKKEVQ 3111



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 78/373 (20%), Positives = 136/373 (36%), Gaps = 47/373 (12%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V + Q +   CE++   + +V W  +G  V  + G I          L +  A   D+GT
Sbjct: 4727 VVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGT 4784

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+ T  NA   L CS  ++V    V  +       ++D  V      +  C +     P 
Sbjct: 4785 YTVTVENA-NNLECSSCVKV----VEVIRDWLVKPIRDQHVKPKGTAIFACDI-AKDTPN 4838

Query: 545  ITWL-----LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
            I W      +  +P        +     L I++A+PED   Y    E         A +T
Sbjct: 4839 IKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK----RYPAKLT 4894

Query: 600  VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
            + E    R+ E L P+               D+ + +    +   ++S    P   W   
Sbjct: 4895 LGE----REVELLKPI--------------EDVTIYEKESASFDAEISEADIPGQ-WKLK 4935

Query: 660  GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
            G  ++ S     +  G +  L + +V  +  G    +A N+     T A+LTV+E     
Sbjct: 4936 GELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAI----TTAILTVKE----I 4987

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
            +  F    + VT    +     C +  +    V W + G  + K +  F+++ +     L
Sbjct: 4988 ELDFAVPLKDVTVPERRQARFECVLTRE--ANVIWSK-GPDIIKSSDKFDIIADGKKHIL 5044

Query: 780  VLKKVQPWHAGQY 792
            V+   Q    G Y
Sbjct: 5045 VINDSQFDDEGVY 5057



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F+K + ++EV E    +  C++   P  EV+W+K D+ I E+  ++I   E     L+I 
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6025

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1862
            +   +D   Y C+  +S  +      EL  E + + +     EGE+ E
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)

Query: 8     ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
             A+  ISK S S  P  + +    E P   + P+    + +  G T + E  V G P P +
Sbjct: 17103 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17160

Query: 65    TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              W R  + I    R    C I+ T     L++      D G+Y   A+N +G++   V +
Sbjct: 17161 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17216

Query: 122   TV 123
              V
Sbjct: 17217 KV 17218



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             ++VK G     +    GRP P V W K +  L+  A V  ++      L I   N++D G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19756

Query: 230   VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
              YT  + N    AS++  L ++ LD+        T  T  DV KE
Sbjct: 19757 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19795



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 1/90 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +K  ++++ +  V G P P V WF +G  + ++  ++E+ +  GS  L +  A     G 
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGV 21531

Query: 485   YSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
             Y+  A NA G       ++V+      V P
Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQDTPGKVVGP 21561



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1813
             + P       D+ + EG      C   G P PEV W    + I  +E   F I+ + D  
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 26888

Query: 1814  CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
              +LII DV   D   YT    N  G  + T  + + ++
Sbjct: 26889 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 24/96 (25%), Positives = 43/96 (44%)

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
            +C P    +   ++V EG+           P P V+W K    ++ S R+++   +    
Sbjct: 7887 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 7946

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
            LE+    + D G+YT  + N  G A+ S  + + GL
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)

Query: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 570
            P+      D  VIEG+   +    R  PVP ++W  +G+ ++ + R T +     A L +
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949

Query: 571  QDALPEDHGTYTCLAENALGQVSCSAWVTV 600
              ++  D G YT   EN LG  + S  V V
Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 57/244 (23%), Positives = 94/244 (38%), Gaps = 35/244 (14%)

Query: 395  VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV 454
            VSK +    P + QR    P  + K +  EV+E   V    ++ G+P P + WF    P 
Sbjct: 9602 VSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNIVAKIKGVPFPTLTWF--KAPP 9658

Query: 455  RRQEGSIEVYEDAGSHYL-----CLL---KARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
            ++ +    V  D   + L     C L   ++R  D+G Y+ TA N  G  S    L V  
Sbjct: 9659 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLG 9718

Query: 507  LAVMEVAP-SFSSVLKDCAVI-------EGQDFVLQCSVRGTPVPRITWL-LNGQPIQYA 557
                 V P  F SV  D   +       +G   +    +      R TW+ ++ +P    
Sbjct: 9719 RPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP---- 9774

Query: 558  RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAP 617
               C   + +L     L      +  +A+N  G         +  +  + ++ + +P AP
Sbjct: 9775 -KECTYTIPKL-----LEGHEYVFRIMAQNKYG-----IGEPLDSEPETARNLFSVPGAP 9823

Query: 618  SKPT 621
             KPT
Sbjct: 9824 DKPT 9827



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)

Query: 1762  KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
             K I  L V  G+  RF   I G P P   W  D   I+   H+ ++ D   +  L I + 
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076

Query: 1822  CGDDDAKYTCKAVNSLGEATCTAELIV 1848
                D  +Y     N+ G  T    L V
Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTV 11103



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 23/80 (28%), Positives = 36/80 (45%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G++ ++   I G P P V W +DGK L +     E+       TLV+K       
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279

Query: 790   GQYEILLKNRVGECSCQVSL 809
             GQY + L N  G  S  +++
Sbjct: 18280 GQYILKLSNVGGTKSIPITV 18299



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 26/85 (30%), Positives = 34/85 (40%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L+L   V   P   IIWT   K L   + + L   G   +  I+     D G
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y    KN +G    S  V V D+P
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDSP 22644



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)

Query: 604  KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
            K SR +E +  V   + P   + ++ L+ L V  G+++ +   V+G P P++ W      
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233

Query: 663  IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +++ +    E    + ++ I +    DTGTY  EA N  G  R  AV+ V
Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7281



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)

Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
            K +  L V  G+       + G P+P++ W K D  +++ +   I+ +     ++ I D 
Sbjct: 7198 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7256

Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIV 1848
               D   Y  +AVN  G AT   E+ V
Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)

Query: 1331 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1389
            P PP      + I  ++  L W     DGGS + +Y +E  D   K W+ +  T + T  
Sbjct: 7587 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7645

Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSE 1414
             V  L     Y FRV A N  G S+
Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSD 7670



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P  IL P  + IK G   + E  V G P P   W +    + +     +      +  L+
Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12460

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I  V  +D G Y+  A N SG     +++ V
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 38/145 (26%), Positives = 62/145 (42%), Gaps = 18/145 (12%)

Query: 484   TYSCTASNAQGQLSCSWTLQVERLAV-MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
             ++  +A N +G +S    L V  +A  + + P+F  +     V+ G+D  +     G P 
Sbjct: 15621 SFRVSAQNEKG-ISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPT 15679

Query: 543   PRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
             P +TW  +  P+ Q  R   E+    + L I+DA  ED G Y     N+ G+   +  V 
Sbjct: 15680 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVI 15739

Query: 600   VHEKKSSRKSEYLLPVAPSKPTAPI 624
             V +K             P  PT P+
Sbjct: 15740 VLDK-------------PGPPTGPV 15751



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 20/81 (24%), Positives = 39/81 (48%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VV  G+  +    I G+P P + W+KG+  L  +AR+ +   +    L +    + D G
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y     N +G+ S++  + +
Sbjct: 16116 NYILKAKNVAGERSVTVNVKV 16136



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             ++ G   K E  + G P+P +TW ++G P+    R  +   +  T +L I   H++D G+
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16802

Query: 104   YTCEATNGSGARQVTVEL 121
             Y     N  G +  ++E+
Sbjct: 16803 YGITVANVVGQKTASIEI 16820



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             ++P          +  G   + +  + G P P + W KD + ++++    ++ +   +  
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17871

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   DD  KYT  A NS G AT    +IV
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/74 (31%), Positives = 33/74 (44%)

Query: 639   QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
             Q+ + V   G P   V W  +G  ++E+   +     T  SL I+E   ED GTY     
Sbjct: 18914 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 18973

Query: 699   NSAGEVRTQAVLTV 712
             NSAG +     + V
Sbjct: 18974 NSAGSITVPITIIV 18987



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)

Query: 711   TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 757
             +V EP + T P  +      PR          +    G+ + I+  IAG P P + W +D
Sbjct: 19270 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19329

Query: 758   GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 808
             G  + ++    E++  ++   L +K       GQY + LKN  G  S  V+
Sbjct: 19330 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19379



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F+K + D  V EG+ A  +C++    + +V WFK+   I +S+ ++I  D      L+I 
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5847

Query: 1820 DVCGDDDAKYTCKA 1833
            D   +D   YTC A
Sbjct: 5848 DCTPEDIKTYTCDA 5861



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + ++ G T +   RV+G PEP +TW + G+ +    R  L   +     L I      D 
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11479

Query: 102   GKYTCEATNGSGARQ 116
             GKY   A N SG  Q
Sbjct: 11480 GKYIISAKNSSGHAQ 11494



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 55/398 (13%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V+  QT++    V G P+P++ W  EG  + R E  +++ +D     L + +A   D G 
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVR-EKRVDLIQDLPRVELQIKEAVRADHGK 11481

Query: 485   YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
             Y  +A N+ G    S  + V       + L V  V     ++  +  +  G   +    V
Sbjct: 11482 YIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIV 11541

Query: 538   RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ-DALPEDHGTYTCLAENALGQVSCSA 596
                           +P Q   S   + V +  I+ + L  +   +   AEN +G      
Sbjct: 11542 E-----------YRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVG-----V 11585

Query: 597   WVTVHEKKSSRKSEYLLPVAP-SKPTAPIFLQGLSDLKVMDGSQVTMTVQ-----VSGNP 650
               T+  K        +L + P  +P  P       +L + D  +  + ++       G  
Sbjct: 11586 GPTIETKTP------ILAINPIDRPGEP------ENLHIADKGKTFVYLKWRRPDYDGGS 11633

Query: 651   PPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGE---VR 705
             P   +  H    ++ S+D+    +G+  +    +          +  +  N  GE   V+
Sbjct: 11634 PN--LSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVK 11691

Query: 706   TQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CK 763
             T+ V+  +   D  +P    K   V T   G ++ +   + G PFP V W +D  A    
Sbjct: 11692 TEEVVVKE---DLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLT 11748

Query: 764   DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              +   ++    D     L K +    G+Y +   N  G
Sbjct: 11749 RSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAG 11786



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             VK    V     V G P P V+W  +GT ++  EG I++        L L     +DSG 
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEG-IKMAMQRNLCTLELFSVNRKDSGD 12868

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y+ TA N+ G  S +  L+V
Sbjct: 12869 YTITAENSSGSKSATIKLKV 12888



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 37/148 (25%), Positives = 64/148 (43%), Gaps = 24/148 (16%)

Query: 490   SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             S++ G ++    +++ R+++    P F   +    V  G+ F L+  V G P+P I WL 
Sbjct: 17111 SDSTGPITAKDEVELPRISM---DPKFRDTI---VVNAGETFRLEADVHGKPLPTIEWLR 17164

Query: 550   NGQPIQYARSTCEAG----VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
               + I+ + + CE       A L ++DA+  D G Y   A N  G  S    V V ++  
Sbjct: 17165 GDKEIEES-ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-- 17221

Query: 606   SRKSEYLLPVAPSKPTAPIFLQGLSDLK 633
                        P  P  P+ + G++  K
Sbjct: 17222 -----------PGPPEGPVQVTGVTSEK 17238



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)

Query: 20    DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
             DP+ V    L     E P  IL     R   IK G T +    ++G P P+VTW +  + 
Sbjct: 10702 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10761

Query: 73    ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
               +  R  +D    G+   + +A H ED G Y+    N +G++ V+V++ V
Sbjct: 10762 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10809



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 3/82 (3%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWF--LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
             VK   T++    V G P PEVAW    + T + R    +++   A S    L KA+  D 
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP-RVKIDTRADSSKFSLTKAKRSDG 11774

Query: 483   GTYSCTASNAQGQLSCSWTLQV 504
             G Y  TA+N  G      T+ V
Sbjct: 11775 GKYVVTATNTAGSFVAYATVNV 11796



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)

Query: 598   VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
             V V+EK  S      +P VA      P      S   V  G  + + V +SG P P + W
Sbjct: 16707 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16766

Query: 657   LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 715
               +G  ++++   +        +L I+E   +D G Y     N  G+   +  ++T+ +P
Sbjct: 16767 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16826



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 575
             KD  V+  G+ FVL+  +RG P+P + W  +G+ ++   AR   ++ + +  L ++D + 
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y     N  G  S    V V ++             P  P  P+ + G++
Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18318



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 87/450 (19%), Positives = 159/450 (35%), Gaps = 68/450 (15%)

Query: 421   QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
             Q+  V+   +++      G P P   W     P        +++       L +      
Sbjct: 21868 QTHVVRAGASIRLFIAYQGRPTPTAVW---SKPDSNLSLRADIHTTDSFSTLTVENCNRN 21924

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y+ T  N  G  S ++T++V         +   +V    ++++ D  +++G   + 
Sbjct: 21925 DAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPLLDGGARIH 21984

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                V      R +W       Q     C   + +++              LAE       
Sbjct: 21985 HYVVEKREASRRSW-------QVISEKCTRQIFKVND-------------LAEGVPYYFR 22024

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              SA   V+E       E   P+  ++  AP        L V+D S+ +  +         
Sbjct: 22025 VSA---VNEYGVGEPYEMPEPIVATEQPAPP-----RRLDVVDTSKSSAVLA-------- 22068

Query: 654   VIWL---HNGNEI---------QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNS 700
               WL   H+G            Q+  DF  E   T Q +  ++ +  +    +  +A N 
Sbjct: 22069 --WLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKND 22126

Query: 701   AGEVRTQAVLT---VQEPH-DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
             AG    +   +   ++EP  + T        + +T   G    I   I+G P P V W  
Sbjct: 22127 AGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKL 22186

Query: 757   DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             +   L K+T    +   +D  TL +K      +G+Y + L+N  G  +  V++++     
Sbjct: 22187 EEMRL-KETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPG 22245

Query: 817   RAL-PRGREPASCED-LCGGGVGADGGGSD 844
                 P      S E  +   G   DGGG++
Sbjct: 22246 PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
            G  AKF   ++  P  +  W + G+ I    +    C IR +    SL I      D G+
Sbjct: 4351 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4406

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            YTC+A+N  G+   T  LTV        G+  V K L +R   P  E
Sbjct: 4407 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4449



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)

Query: 1737 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1790
            S +D SQ  +EA+   +E K  V    PYF+  ++D   VE       C+I    D  V 
Sbjct: 5494 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5552

Query: 1791 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            WFKD + I+ S++  I  D      LI+      D  +YTC
Sbjct: 5553 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5592



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)

Query: 21   PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
            PSR    + ++   EAP   L  +    L +K G   +    V G PEP++TW +    +
Sbjct: 7175 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7234

Query: 74   TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                R  ++  +    ++ I      D G Y  EA N  G     VE+ V
Sbjct: 7235 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 68/354 (19%), Positives = 126/354 (35%), Gaps = 56/354 (15%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E + +        +P P V+W  +G  V+  +  + +  D  S +L + K+   D+G 
Sbjct: 7901 VIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD-RLTMKNDHISAHLEVPKSVRADAGI 7959

Query: 485  YSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
            Y+ T  N  G  + S  ++V       + +   ++  S   +  +    +G   +L   +
Sbjct: 7960 YTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVL 8019

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
                  R T++    P+    +     V     +D +P     +   A N +G       
Sbjct: 8020 ERREAGRRTYI----PVMSGENKLSWTV-----KDLIPNGEYFFRVKAVNKVG------- 8063

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                        E   PV    P  P       D++V + +   MT+  +  PP     L
Sbjct: 8064 -------GGEYIELKNPVIAQDPKQPP--DPPVDVEVHNPTAEAMTI--TWKPP-----L 8107

Query: 658  HNGNEIQESEDFHFEQRGTQH-SLCIQEVFPEDTGTYTCEAWNSAGE----VRTQAVLTV 712
            ++G             +G +    C + + P    TYT +      E    VR +    +
Sbjct: 8108 YDGGSKIMGYIIEKIAKGEERWKRCNEHLVP--ILTYTAKGLEEGKEYQFRVRAENAAGI 8165

Query: 713  QEPHDGTQPWFISKP---------RSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
             EP   T P     P          S+    G  + +  +I+G P+PT+ W++D
Sbjct: 8166 SEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKD 8219



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 105/504 (20%), Positives = 176/504 (34%), Gaps = 76/504 (15%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             L I+ G      GR  G P+P+V+W ++   +    R  +      T +L        D 
Sbjct: 10331 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10389

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
             GKY     N +G+R+   ++ V      + G PV   +    F     +     W     
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV----VDRPGPPVGPVS----FDEVTKDYMVISWKPPLD 10441

Query: 162   KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIH 221
                +K+   ++++ ++G+            V     +   + + +VS   +    +  IH
Sbjct: 10442 DGGSKITNYIIEKKEVGK-----------DVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490

Query: 222   GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVRK 273
               N    G+   LV +     SM A+   +  D+ ++  V E    ++        D  K
Sbjct: 10491 AENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGK 10543

Query: 274   EVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQPP 317
              +TN I ++ +  S   A  +K+                C    R  +        P PP
Sbjct: 10544 PITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPP 10603

Query: 318   RE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERKR 373
              +   +K    K SP   P+       S  +T Q  R     +  G  V     G+E  R
Sbjct: 10604 SKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWR 10663

Query: 374   PAPPRPATFP-TRQPGLGSQD-VVSKAANRRIPMEGQRDSA------FPKFESKP----- 420
              A   P + P T+    G +D    K     +   G+ D A        K   +P     
Sbjct: 10664 RANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELIL 10723

Query: 421   -----QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
                  + Q +K   T++    + G+P P+V W  E       +  I+V    GS  L + 
Sbjct: 10724 DANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDA-PTKARIDV-TPVGSK-LEIR 10780

Query: 476   KARTRDSGTYSCTASNAQGQLSCS 499
              A   D G YS T  N  G  + S
Sbjct: 10781 NAAHEDGGIYSLTVENPAGSKTVS 10804



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 23/81 (28%), Positives = 34/81 (41%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +VVK G   RF   I G P P   W      ++     +V   N   VL I    + D G
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11082

Query: 230   VYTCLVVNGSGKASMSAELSI 250
              Y   V N +G  +++  L++
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTV 11103



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             +++ A + +     +  P  V      EAP   L     + + ++ G +A+     +G P
Sbjct: 17496 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17555

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P++TW R     T   +  ++ G+  T  L I      D GKY  +  N SG++   V 
Sbjct: 17556 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17612

Query: 121   LTV 123
             + V
Sbjct: 17613 VKV 17615



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 1107  VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
             V +  G  L L   VS  PP  I W+  G  L +   I  ++  SL  + ++K    D G
Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23016

Query: 1167  LYKCVAKNDAGQAECSCQVTVDDAP 1191
              Y   A+N +G+   +  V V D P
Sbjct: 23017 KYTIEAENQSGKKSATVLVKVYDTP 23041



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 779
            P F    +SV    G +      I+G P P V W RDG+ +   T    ++  ++    L
Sbjct: 6    PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
             +  V   ++G+Y +   N  G+ +    L+++  +A        P   + L    +   
Sbjct: 66   TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116

Query: 840  GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 893
             G   R      G P     +    DG +++  L  ++            E         
Sbjct: 117  QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 894  QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 953
             ++  + +G+  ST  L     +E+PA++     +   Q+     +  E+K+ +    D 
Sbjct: 175  SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231

Query: 954  RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 1005
            RS+    +   G +   +P K PP  P  P  RS     +  K +L  +   S       
Sbjct: 232  RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287

Query: 1006 KAVESSKPLSNAQPSGPLKPVGNAKPA 1032
                S  P+ + +   P  PV +  PA
Sbjct: 288  ---HSPSPVRHVRAPTP-SPVRSVSPA 310



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1806
            E V  + P  KP       D+ V+EG            P P V W KD + ++ S    +
Sbjct: 7879 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 7938

Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   +  L +      D   YT    N LG AT +  + V
Sbjct: 7939 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)

Query: 518  SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 575
            SV     ++ G+   +   V G PVP   W      +   R   +     +EL I+DAL 
Sbjct: 8612 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8671

Query: 576  EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
            +DHG Y   A N+ G    +A V V +         +L + P      + L   SD +  
Sbjct: 8672 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8726

Query: 636  DGSQVT 641
             GS++T
Sbjct: 8727 GGSEIT 8732



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)

Query: 735  GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 785
            G  + I   I G P P   W  DGKA    KD  H        E  +N  V  +++ + +
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9385

Query: 786  PWHAGQYEILLKNRVGE--CSCQVSLM 810
              H G+Y I  KN+ G+   +C+V +M
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVM 9412



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)

Query: 668   DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             D HFE  G    H    + +     G ++ E   S G +  +    V  P     P +  
Sbjct: 15998 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16054

Query: 726   KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
                ++    G+S  +   I G P PT+ W++  + L  +T   E+   +   +L +K   
Sbjct: 16055 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16110

Query: 786   PWHAGQYEILLKNRVGECSCQVSL 809
                +G Y +  KN  GE S  V++
Sbjct: 16111 RVDSGNYILKAKNVAGERSVTVNV 16134



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + V  G  + +  +V G P P++ W   G  +   +     Q   +  L I+E    D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480

Query: 692   TYTCEAWNSAGEVRTQAVLTV 712
              Y   A NS+G  +  A++ V
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV 11501



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             SV A  G+ V +     G P PTV W +D K L  D   + +   +    L + +V    
Sbjct: 20783 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20841

Query: 789   AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 831
              G+Y + ++N VGE           SS  ++     PA+C+ L
Sbjct: 20842 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 20875



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L+   +G P P I+WL +G P+   ++ R +       L I++A  E  G YT +
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
              +NA+ +++    V             L P  PSKP  PI
Sbjct: 21141 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21167



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)

Query: 1215 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
            G E+  T   + PAP   P    PP ++   ++  V  GESV L   ++G    T TW +
Sbjct: 875  GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               QI+ S   ++      ++L I  A  E  G +T    N+ G+      L V
Sbjct: 933  EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 614  PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            PV  ++P  P    + +     +++M G  + +   V+G P P  +W     E+ + +  
Sbjct: 8595 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8653

Query: 670  HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
              +  GT+  L I++   +D G Y   A NS G
Sbjct: 8654 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8686



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
             L +K G T + E  VRG P P+V W   ++   +T   R  +D     + FSL       
Sbjct: 11714 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11771

Query: 99    EDRGKYTCEATNGSGA 114
              D GKY   ATN +G+
Sbjct: 11772 SDGGKYVVTATNTAGS 11787



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 91/425 (21%), Positives = 154/425 (36%), Gaps = 61/425 (14%)

Query: 403   IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
             IP EG+ D+   K      +  ++   T++    V G P P++ W      +R + G ++
Sbjct: 13192 IPPEGELDADLRK------TLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LD 13244

Query: 463   VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPS 515
             +       +L        D+G Y  T  N+ G+   +  ++V         + V E++  
Sbjct: 13245 IKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKD 13304

Query: 516   FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALP 575
              + V  +  +I+G   ++   V+     R +W         +  T E       + +   
Sbjct: 13305 SAYVTWEPPIIDGGSPIINYVVQKRDAERKSW---------STVTTECSKTSFRVANLEE 13355

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 635
                  +   AEN  G         + +   +R +     V  S+   P+      DLKV 
Sbjct: 13356 GKSYFFRVFAENEYG---------IGDPGETRDA-----VKASQTPGPVV-----DLKVR 13396

Query: 636   DGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQH---SLCIQEVFPEDTG 691
               S+ + ++   G   P       G+ I     DF  E+   Q    SL +Q    + T 
Sbjct: 13397 SVSKSSCSI---GWKKPHS---DGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTE 13450

Query: 692   ----TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAI 744
                 T+   A N  GE  T + +TV    D   P    K        A    +  +   I
Sbjct: 13451 GKEYTFRVSAENENGE-GTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13509

Query: 745   AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 804
              G P P+V W +    L  DT    V  +    TL++   Q   AG+Y I LKN  G   
Sbjct: 13510 KGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568

Query: 805   CQVSL 809
               +S+
Sbjct: 13569 GTISI 13573



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             PAF L      +  G   K +    G P P VTWH++  P+    R   +        L 
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15709

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
             I     ED G Y  + TN +G    T+ + V        G   + +   D  +       
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15764

Query: 153   PSIWGECPPKF 163
                WG  PPK+
Sbjct: 15765 ---WG--PPKY 15770



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD  VV  G   R +  + G P P + W + D+ I ES   +I  + D    LI+ D   
Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17193

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y  +A N  G
Sbjct: 17194 IDGGQYILRASNVAG 17208



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 22/83 (26%), Positives = 37/83 (44%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             +  K G        I+GRP P+VTW    + L+ + RVS++       L +    + D G
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y   + N +G  + S  + + G
Sbjct: 22220 RYFLTLENTAGVKTFSVTVVVIG 22242



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)

Query: 541  PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
            PV    W+ +N +PI+  +   E GV        +P+        A NA+G         
Sbjct: 7828 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7871

Query: 600  VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
                + S  SE ++   P  KPT  +      D+ V++G ++++ V     P P V W  
Sbjct: 7872 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925

Query: 659  NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 717
            +G E++ S+    +       L + +    D G YT    N  G       V  +  P  
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 7983

Query: 718  GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 771
               P    K   +T S       SC +  +P       P +H++ + +   + T +  V+
Sbjct: 7984 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8033

Query: 772  QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
              E+  +  +K + P     + +   N+VG
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8063



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 620  PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 672
            PT  + L    D +KV  G  V +   V+G P P++ W  N   I++  D          
Sbjct: 8898 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 8957

Query: 673  QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
            +   +  L I +   ED GTYT  A N  G V
Sbjct: 8958 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 8989



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/73 (27%), Positives = 33/73 (45%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V++K G+  R    ++GRP P + W K    L+ +A++ +   +    L      + D G
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033

Query: 230   VYTCLVVNGSGKA 242
              YT    N  G A
Sbjct: 15034 AYTLTATNPGGFA 15046



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
             +AP   L P+    + +  G T   E  +RG P P V W ++G+ +  +  R  +   I+
Sbjct: 18206 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18265

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              T +LV+      D G+Y  + +N  G + + + + V
Sbjct: 18266 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 617   PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 663
             PS+ T PI ++        + D+K  D      G  + +   ++G P P + W  +G EI
Sbjct: 19274 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19333

Query: 664   QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
             +E              L +++    DTG Y     N AG
Sbjct: 19334 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19372



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 20/83 (24%), Positives = 38/83 (45%)

Query: 1109  VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
             +  G+ L ++  V   P   + W  +G  ++    + ++      S+ +  A  + RG+Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532

Query: 1169  KCVAKNDAGQAECSCQVTVDDAP 1191
                AKN +G A+   +V V D P
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTP 21555



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1825
            ++++ G   R    + G P P  VW K++  + + R   +  D  G  S LII D    D
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8673

Query: 1826 DAKYTCKAVNSLGEATCTAELIV 1848
              +Y   A NS G     A + V
Sbjct: 8674 HGRYVITATNSCGSKFAAARVEV 8696



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +T  +GQ++ I   + G P P + W ++GK L ++    +++Q+     L +K+      
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11479

Query: 790   GQYEILLKNRVG 801
             G+Y I  KN  G
Sbjct: 11480 GKYIISAKNSSG 11491



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             G +  L  +V G P+P ++W  +G   +P +  +   +  +  L +     +D G YT  
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872

Query: 585   AENALGQVSCSAWVTVHEK 603
             AEN+ G  S +  + V +K
Sbjct: 12873 AENSSGSKSATIKLKVLDK 12891



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)

Query: 19    VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
             VDP R+   P  +          + +  G + K +  + G P P + W +  Q +++  R
Sbjct: 16041 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16092

Query: 79    FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
               +      T SL +      D G Y  +A N +G R VTV + V        G  V+S 
Sbjct: 16093 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16151

Query: 139   TLGDR 143
                ++
Sbjct: 16152 VTAEK 16156



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 81/409 (19%), Positives = 147/409 (35%), Gaps = 65/409 (15%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI--EVYEDAGSHY--LCLLKARTR 480
             V+   + +      G P PE+ W        R+EG    +V  + G +Y  L +      
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITW-------SREEGEFTDKVQIEKGVNYTQLSIDNCDRN 17591

Query: 481   DSGTYSCTASNAQGQLSCSWTLQV-------ERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
             D+G Y     N+ G  S   T++V       + LAV EV    + ++ +  +I+G   V 
Sbjct: 17592 DAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVK 17651

Query: 534   QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
                +      R           YA  + +       +++        +  +AEN  G   
Sbjct: 17652 NYVIDKRESTRKA---------YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG--- 17699

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                 V V    + + +E   P  P K T            + D SQ + ++       PE
Sbjct: 17700 --VGVPVETVDAVKAAEP--PSPPGKVT------------LTDVSQTSASLMWE---KPE 17740

Query: 654   VIWLHNGNEIQESEDFHFEQRGTQH-------SLCIQEVFPEDTGT---YTCEAWNSAGE 703
                 H+G           + +GT+         +C   V    +G    +  +A+N  G+
Sbjct: 17741 ----HDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGK 17796

Query: 704   VRTQAVLTVQEPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
                + +       D T QP       + +   G+ + I   + G P P + W++DG+ L 
Sbjct: 17797 SDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPL- 17855

Query: 763   KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             K T    V +      L +K+      G+Y +   N  G  +  +S+++
Sbjct: 17856 KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)

Query: 1740  DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
             D S +    +A+E+   +P F   S+  + L V  G++        G P P V+W K D 
Sbjct: 19670 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19728

Query: 1797  SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1852
              +R   +       D   SL I +   +D  KYT    N L  A+ T  L+V+ ++
Sbjct: 19729 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19779



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)

Query: 38    PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
             P   + ++ G+  K +  + G P P+VT  R+G P+ +  RF  +       ++ +    
Sbjct: 19985 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20043

Query: 98    EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
               D G+Y   A N SG  +  + + V        G  V+S
Sbjct: 20044 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G+S+ I   + G P P V W +DG  + K   + E+       +L ++     H G Y +
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21534

Query: 795   LLKNRVGECSCQVSLMLQNSSARAL 819
               KN  G    ++ + +Q++  + +
Sbjct: 21535 EAKNASGSAKAEIKVKVQDTPGKVV 21559



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)

Query: 1078 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
            +  H G        + +   P      + V V EG+    +C+V+  P   + W LNG+ 
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834

Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1195
            ++ +K   +  +G +  + I      D G  K  A+N  G  E   ++ +       S  
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893

Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
             +APE    RP+  +      + +     +P   T  K  +  +  +    +KV   ES 
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949

Query: 1256 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1290
            EL  K          + IT   +K RK+ +  E +                   K   +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009

Query: 1291 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1340
             G K+TI         L+   E    +  +    +G    A   + VV KPDP       
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063

Query: 1341 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1400
                       WY +            IE  D     W E   C      ++D+  +   
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101

Query: 1401 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1451
               V+AIN+ G +        Q  +L T  ++ ++     KD +   + +  EP V  + 
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161

Query: 1452 VTINTEQKVSDFY 1464
                 E    D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 57/266 (21%), Positives = 95/266 (35%), Gaps = 45/266 (16%)

Query: 935  PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAE 994
            P+ V E + K+   Q+ DFRSVL            + P P+   P+F     GK +   +
Sbjct: 1871 PEGVIEHKVKLEIQQREDFRSVL-----------RRAPEPR---PEFHVHEPGKLQFEVQ 1916

Query: 995  NGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAK 1054
                  +T   K V   K             + + K  E  + + +     T +    A 
Sbjct: 1917 KVDRPVDTTETKEVVKLKRAER---------ITHEKVPEESEELRSKFKRRTEEGYYEAI 1967

Query: 1055 PDENLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQGTAPAFK-------- 1101
                LKS  K+E  +++      +  H     T+ EK++   E + T P FK        
Sbjct: 1968 TAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELSP 2027

Query: 1102 --------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSL 1152
                    +++Q   V +G     + +V   P     W  NG K  ++ +      E ++
Sbjct: 2028 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2087

Query: 1153 CSVSIEKALPEDRGLYKCVAKNDAGQ 1178
            C + I     ED       A N AG+
Sbjct: 2088 CELVIRDVTAEDSASIMVKAINIAGE 2113



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G  + +   VSG PPP V W  N NE    ++   E      S+ I+       G Y+  
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10099

Query: 697   AWNSAGEVRTQAVLTV 712
             A N AGE +   ++ V
Sbjct: 10100 AKNEAGERKKTIIVDV 10115



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1819
             T RD+  V  G   R   +++G P+P++ W K+ +  +RE R   +D  +D     L I 
Sbjct: 11416 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11472

Query: 1820  DVCGDDDAKYTCKAVNSLGEATCTA 1844
             +    D  KY   A NS G A  +A
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSA 11497



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)

Query: 1749  VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
             V  E+  VK    K + DL+      V  G   R +  + G P PEV W KD  +   +R
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749

Query: 1803  HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               ++  D   + S   ++     D  KY   A N+ G     A + V
Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 22/92 (23%), Positives = 40/92 (43%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G ++ +   V G P P   W    +E+  S      +  +   L I++V  +D+G
Sbjct: 12411 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12470

Query: 692   TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 723
              Y+  A NS+G    +  + V +     QP F
Sbjct: 12471 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             + +  G + R    I+G P PEV W K D  IR++    +        SL++ +V   D 
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16511

Query: 1827  AKYTCKAVNSLG 1838
              KYT    NS G
Sbjct: 16512 GKYTLTLENSSG 16523



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 1758  PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
             P     +   EVV+   G++ +    I G P P + W+KDD+ ++ +    ++   D   
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20431

Query: 1815  SLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
             S++I D    +   Y  K  N++G A+ T
Sbjct: 20432 SILIKDADRLNSGCYELKLRNAMGSASAT 20460



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V  + G   +    I+G+P P + W K +  LQ +A V V     +  + I   ++ + G
Sbjct: 20385 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20444

Query: 230   VYTCLVVNGSGKASMSAELSIQGLD 254
              Y   + N  G A  SA + +Q LD
Sbjct: 20445 CYELKLRNAMGSA--SATIRVQILD 20467



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)

Query: 143  RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
            RF A   E R  +     PK  T    +VV  G+           P+ +  W K N PL 
Sbjct: 6485 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6544

Query: 203  PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 + +E+   ++LE     + D G Y  ++ N  GKA     L +
Sbjct: 6545 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6589



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)

Query: 172  VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
            V+EG       KI G P P +TW K   P +P  +  V   +  N + V     L I   
Sbjct: 9631 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9689

Query: 224  NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
             + D G+YT   VN  G AS    L++ G
Sbjct: 9690 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9718



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAE 586
             G    L   ++G P P++TW    +     AR       ++L I++A  ED G Y+   E
Sbjct: 10736 GDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVE 10795

Query: 587   NALGQVSCSAWVTVHEK 603
             N  G  + S  V V +K
Sbjct: 10796 NPAGSKTVSVKVLVLDK 10812



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 643
             A+N  G +S  +  T   +    K EY  P     PT          L +  G  + +  
Sbjct: 13853 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 13903

Query: 644   VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             + + G P P+  W   G +I+ S+        T   L I+    +D G YT  A N  G 
Sbjct: 13904 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 13963

Query: 704   VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 734
                   +TV +      P  IS   +  A+L
Sbjct: 13964 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 13994



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 634   VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 693
             V  GS + + + +SG P P+V    +G  ++ +  F+ E      ++ ++E    D G Y
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050

Query: 694   TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 725
                A NS+G  +    ++ +  P   T P  IS
Sbjct: 20051 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)

Query: 1743  QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
             +AF   + +E P ++P    T    +++    GS    D  I G P P+V W  ++  ++
Sbjct: 22134 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22192

Query: 1800  ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             E+    I   +D   +L + D    D  +Y     N+ G  T +  ++V
Sbjct: 22193 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)

Query: 1076 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1128
            NC+    G  D    N K S      P      + L+DV V  G+     C++S +    
Sbjct: 5670 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5728

Query: 1129 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
            + W L GK L+ +  ++   EG + ++++     ED G  +  AK+
Sbjct: 5729 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5774



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 438   SGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
             SG PKP+V+WF +   V  ++    +     +  L  +KA+  DSG Y     N+ G   
Sbjct: 10346 SGKPKPKVSWFKDEADV-LEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRK 10404

Query: 498   CSWTLQVERLAVMEVAP-SFSSVLKDCAVI 526
                 + V       V P SF  V KD  VI
Sbjct: 10405 GFCQVNVVDRPGPPVGPVSFDEVTKDYMVI 10434



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             ++  + G++  +   + G P PT+ WLR  K + +++   E+   +    L++K      
Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17195

Query: 789   AGQYEILLKNRVGECSCQVSL 809
              GQY +   N  G  S  V++
Sbjct: 17196 GGQYILRASNVAGSKSFPVNV 17216



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)

Query: 161  PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
            P   T L   V +EG +   +  IT   +  V W   N  +    +    +      L I
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300

Query: 221  HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
              VN +D  G Y C  +N SGK + SA+L++
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
            T S ++  + E    ++  +A N  G  + ++ L V                + D    P
Sbjct: 8854 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 8898

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
             ++ R S+ G+           + VK G+       +TG P P++ W K    ++     
Sbjct: 8899 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 8948

Query: 205  ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
                +  VS       L I    ++D G YT    N  G    +  + +    S  R+  
Sbjct: 8949 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9008

Query: 261  VRETKA 266
            V + KA
Sbjct: 9009 VTDIKA 9014



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)

Query: 735   GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 794
             G +V     I G P PT  W  DG  + K   H+ V  +     L +K       G+Y+I
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086

Query: 795   LLKNRVGECSCQVSL 809
              + N  G  +  V L
Sbjct: 11087 TVSNAAGSKTVAVHL 11101



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)

Query: 31    EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
             EAP  +L P     L IK G T       + G P P+ +W + G+ I       +     
Sbjct: 13877 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 13936

Query: 87    GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
              +   + +A  + D G+YT  ATN  G +   V++TV
Sbjct: 13937 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 13972



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 16/100 (16%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEAGVAELHIQDALPEDHGTYTCL 584
             G +  ++  V G P P +TW    Q ++  +       A    L+I + +  D G Y   
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 624
             A N +G+V     + VH+              P  PT PI
Sbjct: 14643 ARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14669



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
             I+ G + +    ++G P P+V W +    I      ++D     T SLV+  V+  D GK
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16513

Query: 104   YTCEATNGSGARQVTVELTV 123
             YT    N SG +   V + V
Sbjct: 16514 YTLTLENSSGTKSAFVTVRV 16533



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)

Query: 33    PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
             P+  LP     +K     K +   +G P+  V W ++GQ +    R  +      T SL 
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 18956

Query: 93    IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
             I    +ED G Y    +N +G+  +TV +T+
Sbjct: 18957 IKEASKEDVGTYELCVSNSAGS--ITVPITI 18985



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)

Query: 1782  EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P V W KD++++     + I+ + D +  L I  V  +D  KY     N +GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 1084  TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1142
             +T    ++  +G  P  +    D+ + EGK L + C  + +P   + W+  G+ + + + 
Sbjct: 26818 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 26877

Query: 1143  -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
                 +     L ++ I     +D GLY     N+ G    +  + +
Sbjct: 26878 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F + L ++ V+E   + L C+VS  P A +IW    + +  T    +  EG    + I+ 
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6026

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1219
            A  ED G Y C                                 R P S         +D
Sbjct: 6027 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6045

Query: 1220 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1279
              VK            +  + I  P++ ++  GE  E    ++  +     W +  K ++
Sbjct: 6046 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6095

Query: 1280 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1330
              +   V        L +  A  +  G Y ++V    G+ +A  +LTV++K
Sbjct: 6096 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6142



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 16/82 (19%), Positives = 37/82 (45%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             ++ ++ G+    + + +G+P+P+V+W K    +    R  +        LE     + D 
Sbjct: 10330 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10389

Query: 229   GVYTCLVVNGSGKASMSAELSI 250
             G Y  +V N +G      ++++
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV 10411



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)

Query: 619   KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 676
             KP   + L G+  L V  G  + +   V G P PEV W    +  ++  S     + R  
Sbjct: 11703 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11760

Query: 677   QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                  + +    D G Y   A N+AG     A + V
Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)

Query: 581   YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 640
             +  +A+NA G +S  +  T      + K E  LP     P      +    + V  G   
Sbjct: 17096 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17146

Query: 641   TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 700
              +   V G P P + WL    EI+ES     +    +  L +++    D G Y   A N 
Sbjct: 17147 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17206

Query: 701   AG 702
             AG
Sbjct: 17207 AG 17208



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 104/516 (20%), Positives = 179/516 (34%), Gaps = 49/516 (9%)

Query: 42    LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             + +K G   K    + G P P ++W ++G  I    R  +      T  L +      D 
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19360

Query: 102   GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
             G+Y     N +G R V V   V        G   ++    ++ S     P  +    I  
Sbjct: 19361 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19420

Query: 158   ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL------------QPSA 205
                 K  T      + EG++   SCK+T         LKGN  +            +P  
Sbjct: 19421 YIVEKRETSHLAWTICEGELQMTSCKVT-------KLLKGNEYIFRVTGVNKYGVGEPLE 19473

Query: 206   RVSVSEKNGMQV------LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
              V++   +   V      LEI  V ++ + +  C     S   S  +   I+  +  +  
Sbjct: 19474 SVAIKALDPFTVPSPPTSLEITSVTKESMTL--CWSRPESDGGSEISGYIIERREKNSLR 19531

Query: 260   FVRETKATNSDVRKEVTNV---ISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQP 314
             +VR  K    D+R + T +      E ++ +  AA  S     S   R   P +     P
Sbjct: 19532 WVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFL----P 19587

Query: 315   QPPRESKL-ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
              PP + K+ +S K +   A   P+    +          + +       + S  G E   
Sbjct: 19588 SPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTI 19647

Query: 374   PAPPRPATFPTRQPG---LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
                   A +  R      +G+ D  S +++ +I  E + +  F       ++  VK   +
Sbjct: 19648 SGLTTGAEYVFRVKSVNKVGASD-PSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGAS 19706

Query: 431   VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
                     G P P V W    T +R +   ++  +   S  L +  A   DSG Y+ T  
Sbjct: 19707 FTMTVPFRGRPVPNVLWSKPDTDLRTR-AYVDTTDSRTS--LTIENANRNDSGKYTLTIQ 19763

Query: 491   NAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
             N     S +  ++V          +   V K+ AV+
Sbjct: 19764 NVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVL 19799



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             + V++G + R +  I G+P P   W K    +   A ++ SE +    L I   ++ D G
Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23706

Query: 230   VYTCLVVNGSGKASMSAELSIQG 252
              Y  ++ N  GK ++  ++ + G
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIG 23729



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 1758  PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1816
             P  +  +R   V  G   RF   ++  P  EV W+ +   ++ES   +I Y +  G  +L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 25934

Query: 1817  IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
              I D   DD   Y     N  GEA+  A L V
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   + D++V E   A+F+C++   P     W K  Q I     F++  D   + S++I 
Sbjct: 5345 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5402

Query: 1820 DVCGDDDAKYTCKA 1833
                +D+AKY  +A
Sbjct: 5403 SAAFEDEAKYMFEA 5416



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)

Query: 169   RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
             R+VV  G + R    ++G+P P VTW      L   A +  +  +   V  I    +   
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10093

Query: 229   GVYTCLVVNGSGK 241
             GVY+ L  N +G+
Sbjct: 10094 GVYSLLAKNEAGE 10106



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
             ++ G   +    VRG P P+VTW + G    +  G   L+D        LVI     +D 
Sbjct: 12121 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12176

Query: 102   GKYTCEATNGSGARQVTVELTV 123
             GKY+    N +G + V V + V
Sbjct: 12177 GKYSLTLVNPAGEKAVFVNVRV 12198



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)

Query: 1767  LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
             L V  G+    D  + G P P V W KD   ++ +   ++    +  C+L +  V   D 
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866

Query: 1827  AKYTCKAVNSLGEATCTAELIV 1848
               YT  A NS G  + T +L V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)

Query: 615   VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             VA     AP + L+GL DL  +  + S   + + + G P P V W    + +        
Sbjct: 13475 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13534

Query: 672   EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 721
             E      +L + +    D G YT    N AG +  T ++  V +P   T P
Sbjct: 13535 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13585



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)

Query: 142   DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
             D + AP +   P+I          K G  +V        +  I G+P P+ +W K    +
Sbjct: 13874 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 13923

Query: 202   QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             +PS    ++      +L I    + D G YT    N  G
Sbjct: 13924 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G ++ +   I+G P P V   RDG  L K T  F      +  T+ LK+     
Sbjct: 19988 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20046

Query: 789   AGQYEILLKNRVGECSCQVSLML 811
             AG+YEI   N  G     +++++
Sbjct: 20047 AGRYEITAANSSGTTKAFINIVV 20069



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 509   VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGV 565
             V+++   ++ V+K  A   G    L+  + G P P I W  + + +Q     C      +
Sbjct: 20374 VIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDL 20430

Query: 566   AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
             A + I+DA   + G Y     NA+G  S +  V + +K
Sbjct: 20431 ASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20468



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 19/173 (10%)

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
            V   P+    W   G PV   +  +   E+ G  Y             Y   A N QG  
Sbjct: 7127 VERCPRGSDKWVACGEPVAETKMEVTGLEE-GKWY------------AYRVKALNRQGAS 7173

Query: 497  SCSW-TLQVERLAVMEVAPSFSSV--LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
              S  T +++ +   E    F  V  L    V  G    L  +V G P P+ITW      
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233

Query: 554  I-QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
            + Q  R T E     + + I D+   D GTY   A N  G+ +    V V +K
Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDK 7286



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 16/67 (23%), Positives = 28/67 (41%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
             G    +   + G P P + W+    E+  +     +      SL +++    D+G Y  +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120

Query: 697   AWNSAGE 703
             A N AGE
Sbjct: 16121 AKNVAGE 16127



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 4/106 (3%)

Query: 395   VSKAANRRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEVSGIPKPEVAWFLEG 451
             +SK ++   P+  + +   P+    P+ ++   V   +T +   +V G P P + W L G
Sbjct: 17107 ISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEW-LRG 17165

Query: 452   TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLS 497
                  +    E+        L +  A   D G Y   ASN  G  S
Sbjct: 17166 DKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKS 17211



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++  AT +    ++G PEP+V W +    +T   +      +  +F+ LVI  V   D G
Sbjct: 18622 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18677

Query: 103   KYTCEATNGSGARQVTVELTV 123
             +Y     N SG++   V + V
Sbjct: 18678 RYNLTLENNSGSKTAFVNVRV 18698



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)

Query: 1756  VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
             +KP          V      + D   +G P   V W KD Q+++E+    +   +    S
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 18954

Query: 1816  LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             L I +   +D   Y     NS G  T    +IV
Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            ++D  V E     F+C++      +  WF+++++I +S  + I   +D   +L I D   
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6206

Query: 1824 DDDAKYTCKAVNSLGE-ATCTAELIVE 1849
            DD A Y     N  GE     A LIVE
Sbjct: 6207 DDQANYNVSLTNHRGENVKSAANLIVE 6233



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 411  SAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH 470
            +A PK ++  Q   V   + +         PK E  WF E  P+  +  +I+   +  S 
Sbjct: 6500 AAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTK--TIDTTAEQTS- 6556

Query: 471  YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQ-------VERLAVMEVAPSFSSVLKDC 523
               +L+A+  D G Y     N  G+      L+       V  L V E      S+  + 
Sbjct: 6557 -FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEE 6615

Query: 524  AVIEGQDFVLQCSVRGTPVPRITWLL 549
             + +G   ++   V    + R TW+L
Sbjct: 6616 PLTDGGSKIIGYVVERRDIKRKTWVL 6641



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
            G+  L   S  +K  +S DPS +   PLT   AF+ P  +L   K+G        +    
Sbjct: 6862 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 6919

Query: 58   ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
               GYP P  TW    + + +G R  +   +     LVI      D+G YT +  N
Sbjct: 6920 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 6974



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)

Query: 168   GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
             G + VK G   R    + G+P P+V W K      L  S RV +  +       +    +
Sbjct: 11712 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11771

Query: 226   DDVGVYTCLVVNGSGKASMSAELSI 250
              D G Y     N +G     A +++
Sbjct: 11772 SDGGKYVVTATNTAGSFVAYATVNV 11796



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)

Query: 1761  SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
             S+  + + V  G +AR     +G P PE+ W +++    +    ++  ++  N + +  D
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17586

Query: 1821  VCGDDDA-KYTCKAVNSLG 1838
              C  +DA KY  K  NS G
Sbjct: 17587 NCDRNDAGKYILKLENSSG 17605



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)

Query: 21    PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
             P  V    + E P + L  R    + +++G   +    ++G P P   W + GQ I+   
Sbjct: 23625 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23682

Query: 78    RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
             R ++      T  LVI      D G Y     N  G + V +++ V GS
Sbjct: 23683 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23730



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 730   VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             +    G  + I   ++G P PTV W  + + L ++     +       ++V+K  Q  H 
Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10093

Query: 790   GQYEILLKNRVGE 802
             G Y +L KN  GE
Sbjct: 10094 GVYSLLAKNEAGE 10106



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 26/120 (21%)

Query: 537   VRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             +RG PVP   W  +G  I   ++     +   + L I++ L  D G Y     NA G  +
Sbjct: 11037 IRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKT 11096

Query: 594   CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
              +  +TV +              P  PT PI         ++D +   MT  +S  PP +
Sbjct: 11097 VAVHLTVLD-------------VPGPPTGPI--------NILDVTPEHMT--ISWQPPKD 11133



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
             G A R +  + G P P + W KD + +  +   +I    D + +L+  D    D   YT 
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15037

Query: 1832  KAVNSLGEA 1840
              A N  G A
Sbjct: 15038 TATNPGGFA 15046



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)

Query: 20    DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
             +P+ V   P  E    +LPP         + + I+   T +    ++G P P+V W R+ 
Sbjct: 15344 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15401

Query: 71    QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                   G  L    I  T S   L++  V+  D GKY     N SG++   V + V
Sbjct: 15402 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15451



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             + +  G  + + V + G P PEV W     EI+++         T  SL +  V   D+G
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16512

Query: 692   TYTCEAWNSAG 702
              YT    NS+G
Sbjct: 16513 KYTLTLENSSG 16523



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)

Query: 17    LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
             +++ P  V  + +T E     +P   + ++ G     E   +G P+P ++W ++G P+  
Sbjct: 21050 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21109

Query: 76    GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
                F+         +L I    +E  GKYT    N     ++ V +TV
Sbjct: 21110 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21154



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)

Query: 1745  FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1794
             + E++AE    ++P     I DLE+ +          G++ R    + G P P + W K 
Sbjct: 22931 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 22985

Query: 1795  DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1843
              Q I  +    ID  E  +  LI+  V   D  KYT +A N  G+ + T
Sbjct: 22986 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23032



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   + D  V EG  A F C++  +    VVWFK+D  +  SR   I   E     L + 
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5136

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +V  DD ++   +    + E + TA+L V
Sbjct: 5137 EVTLDDISQIKAQ----VKELSSTAQLKV 5161



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F   ++D+   E  +A F  ++  + +  V WFK+DQ +  +R   +  DE    S+   
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5491

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
            D+  DD ++   +A+    EA  T
Sbjct: 5492 DLSIDDTSQIRVEAMGMSSEAKLT 5515



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/72 (27%), Positives = 32/72 (44%)

Query: 185  TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
            TG P+P  TW  G+  L+   RV +   +    L I    + D G+YT  + N     S 
Sbjct: 6922 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981

Query: 245  SAELSIQGLDSA 256
              ++++    SA
Sbjct: 6982 EIDVNVIARPSA 6993



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)

Query: 10   SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
            S IS+  ++ DP           P   L   ++ + EG         R  P P V+WH++
Sbjct: 7875 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 7926

Query: 70   GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
            G+ + +  R  +          V  +V   D G YT    N  G+   ++ + V G
Sbjct: 7927 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 7981



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 582
             G    L+  VRG P P + W  +       RS        A  ++  +  A   D G Y 
Sbjct: 11719 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11778

Query: 583   CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
               A N  G     A V V +K    ++  ++ V+  + T
Sbjct: 11779 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11817



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)

Query: 40    RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
             + L ++ G T +    V+G P P++TW +    +    R  LD  I+ T F   +    V
Sbjct: 13204 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13259

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
             ++ D GKY     N  G ++ T+ + V
Sbjct: 13260 NKYDAGKYILTLENSCGKKEYTIVVKV 13286



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)

Query: 4     VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
             VK V     S  S S DP         E P F +     + L +K GA+       RG P
Sbjct: 19660 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19717

Query: 61    EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
              P V W +    + +  R  +D     T SL I   +  D GKYT    N   A  +T+ 
Sbjct: 19718 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19774

Query: 121   LTV 123
             + V
Sbjct: 19775 VKV 19777



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)

Query: 517   SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 572
             S + K   V  G  F +    RG PVP + W    +P    R+       +    L I++
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19749

Query: 573   ALPEDHGTYTCLAENALGQVSCSAWVTV 600
             A   D G YT   +N L   S +  V V
Sbjct: 19750 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19777



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
             L V  G+  TMTV   G P P V+W     +++     + +   ++ SL I+     D+G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19756

Query: 692   TYTCEAWN 699
              YT    N
Sbjct: 19757 KYTLTIQN 19764



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            G  KL+     +  +LSV+  ++           I   R+L   E     FE  +  +  
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
              V W+   + I    ++ ++   +  + L +  + ++D GKYT  A    G    + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569

Query: 122  TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
            TV G          +SK L D+                            V E Q   F 
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594

Query: 182  CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
            C++   P  +  WL+    L  +  +        + L I     DD+G YT  V      
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653

Query: 242  ASMSAE 247
            A +  E
Sbjct: 2654 AKLKVE 2659



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)

Query: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1770
            S T  +++E    + ++ +  L+ +++ K  VK              PYF+  + D   V
Sbjct: 5119 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5178

Query: 1771 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            E       C++    D  V WFKD + I  S  + I  D      L I      D  +Y 
Sbjct: 5179 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5235

Query: 1831 CKAVNSLGEATCTAE 1845
            C       +A  T E
Sbjct: 5236 CDCGTDKTKANVTVE 5250



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 30/150 (20%), Positives = 49/150 (32%), Gaps = 11/150 (7%)

Query: 442  KPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWT 501
            K EV W L    V  Q    ++  +   H L +   + RD G Y   A + + +      
Sbjct: 6442 KVEVQW-LRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLE-- 6498

Query: 502  LQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC 561
                    +  AP   +  +D  V  G+   +       P     W    +P+       
Sbjct: 6499 --------LAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT 6550

Query: 562  EAGVAELHIQDALPEDHGTYTCLAENALGQ 591
             A      I +A   D G Y  + +N  G+
Sbjct: 6551 TAEQTSFRILEAKKGDKGRYKIVLQNKHGK 6580



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1160
            + V  G+ + +   V+  P   I W+ N   + K T  + +++E      +   +SI KA
Sbjct: 8911 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 8970

Query: 1161 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
            + ED+G Y   A N  G    +  V V D P+
Sbjct: 8971 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9002



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R+  +  G   R    I+G P P+V W K+D+        +ID    G+  L I +   +
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10785

Query: 1825  DDAKYTCKAVNSLGEATCTAELIV 1848
             D   Y+    N  G  T + +++V
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 575
             +D  V++ G+   +   + G P+P I+W  +G  I+  R+  E    + H    ++D + 
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19357

Query: 576   EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
              D G Y    +N  G  S +    V +K             P  P  P+ + GL+
Sbjct: 19358 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19399



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 44    IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
             ++ GA+ +     +G P P   W +    ++       D     +FS L +   +  D G
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 21927

Query: 103   KYTCEATNGSGARQVTVELTV 123
             KYT    N SG++ +T  + V
Sbjct: 21928 KYTLTVENNSGSKSITFTVKV 21948



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            + D +V EG   + + K+      E VW KD Q ++ S    I  D+  +  L+I D+  
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373

Query: 1824 DDDAKYTCKAVNSLGEAT 1841
            +D   Y+   + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1163
            G ++ +   +   P     W  +GK  K  K  +        L    +   + I +    
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
              G Y   AKN AGQ   +C+V V D P
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKVMDVP 9415



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1830
             GS    D  + G P+P+++W K D+ +       + Y   G  +  +   C   D  KYT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22622

Query: 1831  CKAVNSLG 1838
                 N+ G
Sbjct: 22623 LTVKNASG 22630



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)

Query: 1765 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
            ++LE++EG  A F C I  E +P   V W +DD+++     + +  D      L++ D  
Sbjct: 6062 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6117

Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   Y    V  +G A   A L V
Sbjct: 6118 LQDMGTY----VVMVGAARAAAHLTV 6139



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 614   PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 671
             P+      AP  + L     L +  G    +T + SG P P+V W  +  ++ E +  H 
Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370

Query: 672   EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 702
               + T  +L ++++  +  D+G Y     NS G
Sbjct: 10371 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)

Query: 521   KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 575
             KD  +++ G+ F L+  V G P P + W  +G+ ++   +  E  +A+    L  +D+  
Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15029

Query: 576   EDHGTYTCLAENALG 590
              D G YT  A N  G
Sbjct: 15030 RDSGAYTLTATNPGG 15044



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)

Query: 528   GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 584
             G +  +   + G P+P++T   +G P++          AE   +++++++  D G Y   
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20053

Query: 585   AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 635
             A N+ G       + V ++             P  PT P+ +  +++  V          
Sbjct: 20054 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20100

Query: 636   DGSQVT 641
              GSQVT
Sbjct: 20101 GGSQVT 20106



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 620   PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 679
             P   + L+    +K   G+ V +   +SG P P + W  +  E+Q +     E      S
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432

Query: 680   LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
             + I++    ++G Y  +  N+ G     A + VQ
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20464



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)

Query: 37    LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
             +P + + +  G   +    + G P P  +W   G  +    R  ++   +    L I   
Sbjct: 23246 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23304

Query: 97    HEEDRGKYTCEATNGSGARQVTVELTV 123
                D G+YT E  N +G    T+++ +
Sbjct: 23305 TIRDTGEYTLELKNVTGTTSETIKVII 23331



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)

Query: 1760 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            F++ ++D+   E  + A F+C+    P  +V W+KD   + E   +++  D   +  L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +   D   Y+C  V      T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)

Query: 1694 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1746
            W K G  V+        I + S M +I  ++  K   G+ +  + A  L +   VS   +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399

Query: 1747 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            + +              ++D+ V+EG+ A  +CK+       V W+ +D+ I+     Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)

Query: 1763  TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1819
             ++R L +V  G   R    + G P P+V W K   D  +R+    Q+D   D    L+I 
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12169

Query: 1820  DVCGDDDAKYTCKAVNSLGE 1839
             +   DD  KY+   VN  GE
Sbjct: 12170 NSTRDDSGKYSLTLVNPAGE 12189



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 728   RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 786
             R++    G S+ I   I G P P V W +D   L K+  + E   N + FT L++ +   
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14342

Query: 787   WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 819
             +  G++ + ++N  G+ S  V++ + ++    L
Sbjct: 14343 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14375



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             +D+ VV  G     +  I G P P+VVW KD + + E+             +L++ D   
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276

Query: 1824  DDDAKYTCKAVN 1835
              D  +Y  K  N
Sbjct: 18277 TDGGQYILKLSN 18288



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)

Query: 45    KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
             K G+    +  + G P P+VTW      +    R  +    +   +L +      D G+Y
Sbjct: 22163 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22221

Query: 105   TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
                  N +G +  +V + V G      G   VS          + E+    WGE      
Sbjct: 22222 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22273

Query: 165   TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
             T++   +V++ + G  + ++      R Q +VT L     ++ S RVS   + G+
Sbjct: 22274 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22326



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)

Query: 1771  EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
             E S  R    I+G P P V W K +  +       ++     N +LI+ D    D  KYT
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13557

Query: 1831  CKAVNSLG--EATCTAELI 1847
                 N  G  E T + +++
Sbjct: 13558 ITLKNVAGTKEGTISIKVV 13576



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 19/80 (23%), Positives = 30/80 (37%)

Query: 425   VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             V   +T     ++ G P P+V W  +G  +      +E+        L +      D G 
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281

Query: 485   YSCTASNAQGQLSCSWTLQV 504
             Y    SN  G  S   T++V
Sbjct: 18282 YILKLSNVGGTKSIPITVKV 18301



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 637   GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 694
             G    +   + G P P+V+W  +G E++E+     E + T  + +L +++    D G Y 
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283

Query: 695   CEAWNSAG 702
              +  N  G
Sbjct: 18284 LKLSNVGG 18291



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)

Query: 1733 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1779
            E L+  E+  ++  E+  EE   VK             P     + D    EG       
Sbjct: 4205 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4264

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1838
             I      EV W+ +++ +     F+   D++   +L+I  V  +D   +Y C+A+N  G
Sbjct: 4265 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4321

Query: 1839 EATCTAELIV 1848
            +   +A+L V
Sbjct: 4322 KTATSAKLTV 4331



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)

Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
            NC+   + T    K  E    A  F  K Q++ + EG+K    C +S +    + W  + 
Sbjct: 6036 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6091

Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
            KTL++     +  +G    + ++ A  +D G Y  +     G A  +  +TV
Sbjct: 6092 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6139



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 1765  RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1824
             R L V  G + R    I+G P PEV W KD+ +++   + +   + +    LII +    
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14343

Query: 1825  DDAKYTCKAVNSLGE 1839
             D  K+     N  G+
Sbjct: 14344 DTGKFVMTIENPAGK 14358



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)

Query: 632   LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
             L V  G  + + V + G P PEV W      L N   I+ +E F          L I E 
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14340

Query: 686   FPEDTGTYTCEAWNSAGE 703
                DTG +     N AG+
Sbjct: 14341 NRYDTGKFVMTIENPAGK 14358



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1830
             G   + +  + G P P V W K DQ +++++  +++++     +++ I++    D   Y 
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14640

Query: 1831  CKAVNSLGE 1839
               A N +GE
Sbjct: 14641 LTARNIVGE 14649



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 729   SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 788
             +V    G++  +   ++G P PT+ W +DGK L + T   E+   +    LV K      
Sbjct: 14973 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15031

Query: 789   AGQYEILLKNRVG 801
             +G Y +   N  G
Sbjct: 15032 SGAYTLTATNPGG 15044



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)

Query: 1765  RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
             RD+ VV+ G   + +  I G P P + W KD   I E    +I    D +  L + D   
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19357

Query: 1824  DDDAKYTCKAVNSLG 1838
              D  +Y     N  G
Sbjct: 19358 RDTGQYVLTLKNVAG 19372



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 19/71 (26%), Positives = 30/71 (42%)

Query: 170   VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             V V+ G   +    I+G+P P+VT  +  VPL+ + R +         + +      D G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048

Query: 230   VYTCLVVNGSG 240
              Y     N SG
Sbjct: 20049 RYEITAANSSG 20059



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 1772  GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1830
             G++ R     +G P P  VW K D ++      + D     + S +  + C  +DA KYT
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 21930

Query: 1831  CKAVNSLGEATCT 1843
                 N+ G  + T
Sbjct: 21931 LTVENNSGSKSIT 21943



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 525   VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 583
             V +G    L   ++G P P   W   GQ I + A         EL I++A   D GTY  
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23710

Query: 584   LAENALGQ 591
             + EN  G+
Sbjct: 23711 VLENKCGK 23718


>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
          Length = 819

 Score =  236 bits (601), Expect = 2e-61
 Identities = 149/364 (40%), Positives = 195/364 (53%), Gaps = 72/364 (19%)

Query: 1411 GTSEPSQES------ELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF 1463
            G  EP Q+           V   P   +    V DD    P   ++R V++  E  +S  
Sbjct: 454  GNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVK-ETSISAG 512

Query: 1464 YDI--EERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKL 1521
            Y++   E LG G+FGQV R  EK T    A K  K  SAK++E+++ EI+IMN L H  L
Sbjct: 513  YEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNL 572

Query: 1522 VQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGI 1581
            +Q  DAFE K +  +V+E V GGELF+RI DE + LTE + + + RQI EGV Y+H+  I
Sbjct: 573  IQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYI 632

Query: 1582 VHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYA 1641
            +HLDLKPENI+CVN+TG +IK+IDFGLARR +    LKV FGTPEF+APEV+NYE + + 
Sbjct: 633  LHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFP 692

Query: 1642 TDMWSIGVICYIL------------------------------------------NRL-- 1657
            TDMWS+GVI Y+L                                          +RL  
Sbjct: 693  TDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLV 752

Query: 1658 -------DCTQCLQHPWLMKDTKNMEAK-KLSKDRMK------KYMARRKWQKTGNAVRA 1703
                     TQCL+H WL     N+ AK   SK R+K      KY+A+RKW+K    V A
Sbjct: 753  KEKSCRMSATQCLKHEWL----NNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTA 808

Query: 1704 IGRL 1707
              RL
Sbjct: 809  ANRL 812


>gi|167466233 myosin light chain kinase family, member 4 [Homo
            sapiens]
          Length = 388

 Score =  221 bits (562), Expect = 7e-57
 Identities = 122/287 (42%), Positives = 175/287 (60%), Gaps = 15/287 (5%)

Query: 1448 DYRTVTINTEQKVSDFYDIE--ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN 1505
            D+R VT   +  V+ FY +   E LG G+FGQV +  E  T    A K  K    K+KE 
Sbjct: 89   DHRIVTAK-QGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEE 147

Query: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565
            ++ EIS+MN L H  L+Q  DAFE K +IV+V+E V GGELF+RIIDE + LTE + I +
Sbjct: 148  VKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILF 207

Query: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 1625
            M+QI EG+ ++H+  I+HLDLKPENI+CVN+   +IK+IDFGLARR +    LKV FGTP
Sbjct: 208  MKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTP 267

Query: 1626 EFVAPEVINYEPIGYATDMWSIGVICYIL-----------NRLDCTQCLQHPWLMKDTKN 1674
            EF+APEV+NY+ + + TDMWS+GVI Y+L           +       L   W ++D + 
Sbjct: 268  EFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEF 327

Query: 1675 MEAKKLSKDRMKKYMARRK-WQKTGNAVRAIGRLSSMAMISGLSGRK 1720
             +  + +K+ + K + + K W+ + +       LS   + S L+ +K
Sbjct: 328  QDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQK 374


>gi|14993776 skeletal myosin light chain kinase [Homo sapiens]
          Length = 596

 Score =  220 bits (560), Expect = 1e-56
 Identities = 132/358 (36%), Positives = 186/358 (51%), Gaps = 56/358 (15%)

Query: 1415 PSQESELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF-YDIEERLGS 1472
            PS++SE+          +D  ++ DD    P    +R V + T    S+F  + +E LG 
Sbjct: 234  PSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELRTGNVSSEFSMNSKEALGG 293

Query: 1473 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1532
            GKFG V   +EK T    A K  K  + K+KE +  EI +MN L+H  L+Q   A E   
Sbjct: 294  GKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPH 353

Query: 1533 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1592
             IV+ +E + GGELFERI+DED+ LTE + + ++RQI +G+ ++HK  ++HLDLKPENI+
Sbjct: 354  EIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENIL 413

Query: 1593 CVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652
            CVN TG  +K+IDFGLARR      LKV FGTPEF++PEV+NY+ I   TDMWS+GVI Y
Sbjct: 414  CVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITY 473

Query: 1653 IL---------------------------------------------------NRLDCTQ 1661
            +L                                                    R++  Q
Sbjct: 474  MLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQ 533

Query: 1662 CLQHPW---LMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGL 1716
            CL HPW   L +  K    +  S+  +KKY+ +R+W+K   AV A  R   ++    L
Sbjct: 534  CLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGAL 591


>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
          Length = 1430

 Score =  200 bits (509), Expect = 9e-51
 Identities = 122/364 (33%), Positives = 188/364 (51%), Gaps = 72/364 (19%)

Query: 1452 VTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE------KEN 1505
            +T+  ++ V D+YD  E LGSG+F  V +  EK T   +A KF K    K       +E+
Sbjct: 1    MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED 60

Query: 1506 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1565
            I +E+SI+  + HP ++   + +E K +++++LE+V+GGELF+ + +++  LTE E  ++
Sbjct: 61   IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE-SLTEEEATEF 119

Query: 1566 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFG 1623
            ++QI  GV Y+H   I H DLKPENIM +++     RIK+IDFGLA +++     K +FG
Sbjct: 120  LKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFG 179

Query: 1624 TPEFVAPEVINYEPIGYATDMWSIGVICYIL----------------------------- 1654
            TPEFVAPE++NYEP+G   DMWSIGVI YIL                             
Sbjct: 180  TPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDE 239

Query: 1655 ----------------------NRLDCTQCLQHPWLM-KDTKNMEAKKLS---KDRMKKY 1688
                                   R+     LQHPW+  KDT+   ++K S    ++ KK+
Sbjct: 240  YFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKF 299

Query: 1689 MARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1748
             AR+KW+++   +    RLS     S LS    S       L+    E +  V +A + A
Sbjct: 300  AARKKWKQSVRLISLCQRLSR----SFLSRSNMSVARSDDTLD----EEDSFVMKAIIHA 351

Query: 1749 VAEE 1752
            + ++
Sbjct: 352  INDD 355


>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
          Length = 454

 Score =  191 bits (485), Expect = 6e-48
 Identities = 95/206 (46%), Positives = 138/206 (66%), Gaps = 9/206 (4%)

Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFK------AYSAKEKENIRQEI 1510
            ++ V D Y++ E LGSG+F  V +  +K T K +A KF K      +     +E I +E+
Sbjct: 6    QEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREV 65

Query: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570
            +I+  + HP ++   D FE K ++V++LE+VSGGELF+ + +++  LTE E  ++++QI 
Sbjct: 66   NILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKE-SLTEDEATQFLKQIL 124

Query: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFGTPEFV 1628
            +GV Y+H + I H DLKPENIM ++K     RIKLIDFG+A ++E     K +FGTPEFV
Sbjct: 125  DGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFV 184

Query: 1629 APEVINYEPIGYATDMWSIGVICYIL 1654
            APE++NYEP+G   DMWSIGVI YIL
Sbjct: 185  APEIVNYEPLGLEADMWSIGVITYIL 210


>gi|14670383 death-associated kinase 2 [Homo sapiens]
          Length = 370

 Score =  189 bits (479), Expect = 3e-47
 Identities = 97/206 (47%), Positives = 136/206 (66%), Gaps = 9/206 (4%)

Query: 1457 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK------EKENIRQEI 1510
            +QKV DFYDI E LGSG+F  V +  EK T   +A KF K   ++       +E I +E+
Sbjct: 16   QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75

Query: 1511 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1570
            SI+  + H  ++   D +E + ++V++LE+VSGGELF+ +  ++  L+E E   +++QI 
Sbjct: 76   SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQIL 134

Query: 1571 EGVEYIHKQGIVHLDLKPENIMCVNKTGT--RIKLIDFGLARRLENAGSLKVLFGTPEFV 1628
            +GV Y+H + I H DLKPENIM ++K      IKLIDFGLA  +E+    K +FGTPEFV
Sbjct: 135  DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194

Query: 1629 APEVINYEPIGYATDMWSIGVICYIL 1654
            APE++NYEP+G   DMWSIGVI YIL
Sbjct: 195  APEIVNYEPLGLEADMWSIGVITYIL 220


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score =  186 bits (471), Expect = 2e-46
 Identities = 141/480 (29%), Positives = 206/480 (42%), Gaps = 69/480 (14%)

Query: 364  LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423
            LSP  EE   P    P T PT +P        S + NRR    G +  A P F+     Q
Sbjct: 831  LSPP-EEFPEPGETWPRT-PTMKP--------SPSQNRRSSDTGSK--APPTFKVSLMDQ 878

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
             V+E Q V     V G PKP V+W     PVR  +       + G   L +L A   D+G
Sbjct: 879  SVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAG 938

Query: 484  TYSCTASNAQGQLSCSWTLQV----ERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
             Y+C A N  G   C   L+V    E  ++  +AP     L+D  V  G+  + +C V G
Sbjct: 939  FYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAP-----LQDVDVGAGEMALFECLVAG 993

Query: 540  TPVPRITWLLNGQPIQYARSTC----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCS 595
                 + WL  G+ +Q A   C    +    +L +     +D G YTC    A  +++CS
Sbjct: 994  PTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCS 1053

Query: 596  AWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVI 655
            A +TV                PS   AP+F + L D++V++G       ++SG PPP V 
Sbjct: 1054 ARLTVR---------------PS--LAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVT 1096

Query: 656  WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            W H G  ++ESE+    Q G  HSL I  V  ED G Y   A N+ G+    A L V+EP
Sbjct: 1097 WTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEP 1156

Query: 716  HDGTQ--------------------------PWFISKPRSVTASLGQSVLISCAIAGDPF 749
                                           P F+   + +   L +  ++ C + G P+
Sbjct: 1157 RTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPY 1216

Query: 750  PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
            PT+ W  +G  + + +    + Q  DV  LV   V P HAG Y+ ++ N++G+ +C   L
Sbjct: 1217 PTISWFHNGHRI-QSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL 1275



 Score =  167 bits (422), Expect = 1e-40
 Identities = 167/632 (26%), Positives = 245/632 (38%), Gaps = 82/632 (12%)

Query: 161  PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
            P F   L  VVV  G      C IT  P PQV+W K    L+   R+ +  +     L +
Sbjct: 722  PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLL 781

Query: 221  HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
                  D G Y     N  G+A+ +A L+++               + S     +T   S
Sbjct: 782  REARAADAGSYMATATNELGQATCAASLTVR------------PGGSTSPFSSPIT---S 826

Query: 281  KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340
             E  L   E          P+ G + P     +P P +  +     D+   AP T  +  
Sbjct: 827  DEEYLSPPE--------EFPEPGETWPRTPTMKPSPSQNRR---SSDTGSKAPPTFKVSL 875

Query: 341  TSSSI-----TLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG------- 388
               S+      + + RVQ EP+ P +  L       ++P  P    F     G       
Sbjct: 876  MDQSVREGQDVIMSIRVQGEPK-PVVSWL-----RNRQPVRPDQRRFAEEAEGGLCRLRI 929

Query: 389  LGSQD-----VVSKAANR--------RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC 435
            L ++         KA N         R+ +    +S      +  Q  +V   +   F C
Sbjct: 930  LAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFEC 989

Query: 436  EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495
             V+G    EV W   G  ++      +++ D     L L      DSG Y+C  S A+ +
Sbjct: 990  LVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDE 1049

Query: 496  LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 555
            L+CS  L V       +AP F+ +L+D  V+EG+     C + GTP P +TW   G P++
Sbjct: 1050 LTCSARLTVRP----SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPME 1105

Query: 556  YA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-----SR 607
             +   R   + G+  LHI     ED G Y   A N  GQ  CSA + V E ++     S 
Sbjct: 1106 ESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSS 1165

Query: 608  KSEYLLPVAPSKP--------TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
            K E + P  P +P        + P FL+ L DL+V    +  +  QV+G P P + W HN
Sbjct: 1166 KLEKM-PSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHN 1224

Query: 660  GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE----P 715
            G+ IQ S+D    Q    H L    V P+  G Y     N  G+    A L V +    P
Sbjct: 1225 GHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGP 1284

Query: 716  HDGTQPWFISKPRSVTASLGQSVLISCAIAGD 747
             DG         R VT +      +  AI  D
Sbjct: 1285 PDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPD 1316



 Score =  146 bits (368), Expect = 2e-34
 Identities = 153/593 (25%), Positives = 229/593 (38%), Gaps = 106/593 (17%)

Query: 295  KNCSSPQRGGSPPWAAN---SQPQPPRESKLESCKDSPRTAP-QTPVLQKTSSSITLQAA 350
            + C SP     PP AA+   ++ + P   K E    + R  P  TP L+  +   TL+  
Sbjct: 605  QECRSPV----PPPAADPPEARTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKN 660

Query: 351  RVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQDVVSKAANRRIPMEGQR 409
            R  PE             E+R R  P     + P  + G  SQ    +A      +E   
Sbjct: 661  RAGPE------------AEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPELESSD 708

Query: 410  DSAF---------PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS 460
            DS           P FE   Q+  V     V  +C ++  P P+V+W  +G+ +R  EG 
Sbjct: 709  DSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALR-SEGR 767

Query: 461  IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE--------------- 505
            + +  +   H L L +AR  D+G+Y  TA+N  GQ +C+ +L V                
Sbjct: 768  LLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSD 827

Query: 506  ------------------RLAVMEVAPS---------------FSSVLKDCAVIEGQDFV 532
                              R   M+ +PS               F   L D +V EGQD +
Sbjct: 828  EEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVI 887

Query: 533  LQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENA 588
            +   V+G P P ++WL N QP++  +       E G+  L I  A   D G YTC A N 
Sbjct: 888  MSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNE 947

Query: 589  LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
             G   C A + V     SR    L P              L D+ V  G        V+G
Sbjct: 948  YGARQCEARLEVRAHPESRSLAVLAP--------------LQDVDVGAGEMALFECLVAG 993

Query: 649  NPPPEVIWLHNGNEIQESE---DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVR 705
                EV WL  G  +Q +      HF+  G +  L +  V  +D+G YTC+   +  E+ 
Sbjct: 994  PTDVEVDWLCRGRLLQPALLKCKMHFD--GRKCKLLLTSVHEDDSGVYTCKLSTAKDELT 1051

Query: 706  TQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
              A LTV+       P F      V    G++    C I+G P P V W   G  + +++
Sbjct: 1052 CSARLTVR---PSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPM-EES 1107

Query: 766  GHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818
             +  + Q+  + +L +  V     G Y +   N  G+  C   L ++     A
Sbjct: 1108 ENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAA 1160



 Score =  144 bits (364), Expect = 6e-34
 Identities = 98/356 (27%), Positives = 168/356 (47%), Gaps = 58/356 (16%)

Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1517
            +++SDFYDI + +G G F  + R+VE+ +   +A KF  +  AK K + R+E  ++  L 
Sbjct: 1595 RRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPS-QAKPKASARREARLLARLQ 1653

Query: 1518 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1577
            H  ++   +AFE +  +V+V E+ +  EL ERI  +   + E E   YMRQ+ EG+ Y+H
Sbjct: 1654 HDCVLYFHEAFERRRGLVIVTELCTE-ELLERIARKP-TVCESEIRAYMRQVLEGIHYLH 1711

Query: 1578 KQGIVHLDLKPENIMCVNKTG--TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
            +  ++HLD+KPEN++  +      ++++ DFG A+ L         +GTPEFVAPE++N 
Sbjct: 1712 QSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQ 1771

Query: 1636 EPIGYATDMWSIGVICY------------------------------------------- 1652
             P+   TD+W +GV+ +                                           
Sbjct: 1772 SPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGF 1831

Query: 1653 -----ILNRLDCT--QCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIG 1705
                 + +RL  T  + L+HPW     K  E   +S D +K +++RR+WQ++  + +   
Sbjct: 1832 LIKVLVQDRLRPTAEETLEHPWFKTQAKGAE---VSTDHLKLFLSRRRWQRSQISYKCHL 1888

Query: 1706 RLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFS 1761
             L  +  +      +     P  P  +  L S  D  +  LE +      ++P FS
Sbjct: 1889 VLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFS 1944



 Score =  124 bits (312), Expect = 7e-28
 Identities = 177/805 (21%), Positives = 286/805 (35%), Gaps = 119/805 (14%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
            P F +   +  ++EG       RV+G P+P V+W RN QP+    R   +    G   L 
Sbjct: 869  PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928

Query: 93   IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
            I A    D G YTC+A N  GARQ    L V             S++L            
Sbjct: 929  ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAH--------PESRSLA----------- 969

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
                          L  V V  G+M  F C + G    +V WL     LQP+        
Sbjct: 970  ----------VLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHF 1019

Query: 213  NGMQV-LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
            +G +  L +  V++DD GVYTC +     + + SA L+++   S    F R  +      
Sbjct: 1020 DGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVR--PSLAPLFTRLLE------ 1071

Query: 272  RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKD 327
                         ++ LE  A   +C      G+PP    W     P    E+       
Sbjct: 1072 ------------DVEVLEGRAARFDCKI---SGTPPPVVTWTHFGCPMEESENLR----- 1111

Query: 328  SPRTAPQTPVLQKTSSSITLQAARVQPEPRAP-GLGVLSPSGE---------ERKRPAPP 377
                      L++     +L  A V  E      +  ++  G+         E  R A  
Sbjct: 1112 ----------LRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAAS 1161

Query: 378  RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDS-AFPKFESKPQSQEVKENQTVKFRCE 436
             P++   + P +  +           P +G+ +  + P F    Q  EV   +     C+
Sbjct: 1162 GPSSKLEKMPSIPEE-----------PEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQ 1210

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGS-IEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495
            V+G+P P ++WF  G  ++  +   +  Y D   H L       + +G Y    +N  G+
Sbjct: 1211 VTGLPYPTISWFHNGHRIQSSDDRRMTQYRDV--HRLVFPAVGPQHAGVYKSVIANKLGK 1268

Query: 496  LSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 555
             +C        L V +V P           + G+   L  +    P   +   ++   + 
Sbjct: 1269 AAC-----YAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWN----PPRSLDMAIDPDSLT 1319

Query: 556  YARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE--YL 612
            Y       G  +   +   L E     T L +         +       K S  SE   L
Sbjct: 1320 YTVQHQVLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQL 1379

Query: 613  LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
            L   P+   AP  L     + V++G   ++TV  + +   +V+W      + E+    +E
Sbjct: 1380 LEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYE 1438

Query: 673  QR---GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
                   Q+ L I  V   D G  TC A N  G       L + E      P F S    
Sbjct: 1439 LSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-----PRFESIMED 1493

Query: 730  VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
            V    G++   +  + G P P + W +D + L  ++ H   +  E+  +LV+        
Sbjct: 1494 VEVGAGETARFAVVVEGKPLPDIMWYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQDG 1552

Query: 790  GQYEILLKNRVGECSCQVSLMLQNS 814
            G Y    +N  GE SC+  L + ++
Sbjct: 1553 GVYTCTAQNLAGEVSCKAELAVHSA 1577



 Score =  120 bits (301), Expect = 1e-26
 Identities = 141/591 (23%), Positives = 211/591 (35%), Gaps = 81/591 (13%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
            AP F     ++ + EG  A+F+ ++ G P P VTW   G P+       L     G  SL
Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GGLHSL 1121

Query: 92   VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
             I  V  ED G Y   A N  G    + +L VE       G    S  L    S P    
Sbjct: 1122 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP---SSKLEKMPSIPEEPE 1178

Query: 152  RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
            +  +     P F   L  + V   +     C++TG P P ++W      +Q S    +++
Sbjct: 1179 QGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQ 1238

Query: 212  KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
               +  L    V     GVY  ++ N  GKA+  A L           +V +      D 
Sbjct: 1239 YRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHL-----------YVTDVVPGPPDG 1287

Query: 272  RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRT 331
              +V  V  +   L                      W       PPR   +    DS   
Sbjct: 1288 APQVVAVTGRMVTLT---------------------W------NPPRSLDMAIDPDSLTY 1320

Query: 332  APQTPVLQKTSSSITLQAARVQPEPRAPGLG--------VLSPSGEERKRPAPPRPATFP 383
              Q  VL     +  +   R +P   A GL         VLS + +   +P+PP      
Sbjct: 1321 TVQHQVLGSDQWTALVTGLR-EPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPP------ 1373

Query: 384  TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKP 443
                   S+ V       ++   G      P    KP    V E Q        + +   
Sbjct: 1374 -------SEPV-------QLLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFNHVEAQ 1419

Query: 444  EVAWFLEGTPVRRQEGSIEVYEDAGSHY-LCLLKARTRDSGTYSCTASNAQGQLSCSWTL 502
             V     G  +  + G  E+ +     Y L + +   RD G  +CTA N  G  +CS TL
Sbjct: 1420 VVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTL 1479

Query: 503  QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARS 559
            ++        AP F S+++D  V  G+       V G P+P I W  +   +    +   
Sbjct: 1480 ELAE------APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSF 1533

Query: 560  TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
              E     L +     +D G YTC A+N  G+VSC A + VH  +++ + E
Sbjct: 1534 VYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVE 1584



 Score =  117 bits (293), Expect = 1e-25
 Identities = 91/331 (27%), Positives = 147/331 (44%), Gaps = 25/331 (7%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            AP F + L+DV V EG+     C++S  PP  + WT  G  ++ ++ + L Q+G L S+ 
Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLH 1122

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            I     ED GLY   A N  GQA CS Q+ V++         P   +  P S L      
Sbjct: 1123 IAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE---------PRTAASGPSSKL------ 1167

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
            E   ++ ++P      + ++ P  ++  +D +V   +   L  +VTG    T +W     
Sbjct: 1168 EKMPSIPEEPEQGELERLSI-PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGH 1226

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD-KPDPPA 1335
            +IQ S+  ++    +  +L   A   +H G Y  ++ NKLG      +L V D  P PP 
Sbjct: 1227 RIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPD 1286

Query: 1336 GTPCASDIRSSSLTLSW-----YGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSF 1389
            G P    +    +TL+W        + D  S   +Y+++     +  W  L T  R   +
Sbjct: 1287 GAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSL--TYTVQHQVLGSDQWTALVTGLREPGW 1344

Query: 1390 NVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1420
                L    ++ FRV +  V  +S+PS  SE
Sbjct: 1345 AATGLRKGVQHIFRVLSTTVKSSSKPSPPSE 1375



 Score =  112 bits (281), Expect = 3e-24
 Identities = 76/245 (31%), Positives = 123/245 (50%), Gaps = 13/245 (5%)

Query: 1415 PSQESELTTVGEKPEEPKDEVEVS--DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGS 1472
            P    E T V  +   P  EV  S        P  +  T+     QK   F + + R   
Sbjct: 2918 PEPPPEPTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKAR--- 2974

Query: 1473 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1532
            G+FG V    E  T + +  K    Y+A+ K  + QE  ++  LHH +++   +A+    
Sbjct: 2975 GRFGVVRACRENATGRTFVAKIVP-YAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPR 3033

Query: 1533 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1592
             +V++ E     EL   + D  F  +E +   YM Q+ +G++Y+H   ++HLD+KP+N++
Sbjct: 3034 YLVLIAESCGNRELLCGLSDR-FRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLL 3092

Query: 1593 CVNKTGTRIKLIDFGLARRLENAGSLKVL---FGTPEFVAPEVINYEPIGYATDMWSIGV 1649
                    +K++DFG A+   N  +L+ L    GT EF+APE++  EPIG ATD+W  GV
Sbjct: 3093 LAPDNA--LKIVDFGSAQPY-NPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGV 3149

Query: 1650 ICYIL 1654
            + YI+
Sbjct: 3150 LTYIM 3154



 Score =  111 bits (277), Expect = 8e-24
 Identities = 110/463 (23%), Positives = 180/463 (38%), Gaps = 52/463 (11%)

Query: 916  KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPK 975
            +E+       RA LQR   P+   E             R+V        +P   + P  +
Sbjct: 508  EELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDE 567

Query: 976  PATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETL 1035
            P  P  R   G  +  P E         +   +  S+ +   +   P  P  +   A T 
Sbjct: 568  PGRPRSRGPAGRTE--PGEGPQQEVRRRDQFPLTRSRAIQECRSPVP-PPAADPPEARTK 624

Query: 1036 KPMGNAK--PAETLKPM--------GNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTT 1085
             P G  +  PA+ ++ +        G A P    K+ +  E +K ++     + G  G  
Sbjct: 625  APPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPE-EDGPWGPW 683

Query: 1086 DNE-KRSESQGT-------------------------APAFKQKLQDVHVAEGKKLLLQC 1119
            D    RS+ +G                          AP F+  LQ+V VA G  +LL+C
Sbjct: 684  DRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743

Query: 1120 QVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1179
             ++++PP  + W  +G  L++   ++L  EG   ++ + +A   D G Y   A N+ GQA
Sbjct: 744  IITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQA 803

Query: 1180 ECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPK------ 1233
             C+  +TV    ++    +P        S  PP    E   T  + P  K  P       
Sbjct: 804  TCAASLTVRPGGSTSPFSSPITSDEEYLS--PPEEFPEPGETWPRTPTMKPSPSQNRRSS 861

Query: 1234 ---AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1290
               +  PP       DQ VR G+ V +  +V G      +W++ R+ ++  +    E +E
Sbjct: 862  DTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAE 921

Query: 1291 NG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
             G  +L ILAA +   G YT    N+ G+RQ +  L V   P+
Sbjct: 922  GGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964



 Score =  107 bits (266), Expect = 1e-22
 Identities = 95/352 (26%), Positives = 140/352 (39%), Gaps = 47/352 (13%)

Query: 513  APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH--- 569
            AP F   L++  V  G D +L+C +   P P+++W  +G  ++           E H   
Sbjct: 721  APVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLL 780

Query: 570  IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS--------SRKSEYLLP------- 614
            +++A   D G+Y   A N LGQ +C+A +TV    S        +   EYL P       
Sbjct: 781  LREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEP 840

Query: 615  --VAPSKPT------------------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 654
                P  PT                   P F   L D  V +G  V M+++V G P P V
Sbjct: 841  GETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVV 900

Query: 655  IWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
             WL N   ++ +   F  E  G    L I      D G YTC+A N  G  + +A L V+
Sbjct: 901  SWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVR 960

Query: 714  EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK----ALCKDTGHFE 769
               +      ++  + V    G+  L  C +AG     V WL  G+    AL K   HF+
Sbjct: 961  AHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFD 1020

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
              + +    L+L  V    +G Y   L     E +C   L ++ S A    R
Sbjct: 1021 GRKCK----LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTR 1068



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 74/244 (30%), Positives = 103/244 (42%), Gaps = 26/244 (10%)

Query: 31  EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTF 89
           EAP F +P +N+ +  GA    +  +   P PQV+WH++G  + S GR LL   G R T 
Sbjct: 720 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHT- 778

Query: 90  SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSK----TLGDRF 144
            L++      D G Y   ATN  G       LTV  G        P+ S     +  + F
Sbjct: 779 -LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEF 837

Query: 145 SAPAVETRP----------------SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
             P  ET P                    + PP F   L    V+EGQ    S ++ G P
Sbjct: 838 PEPG-ETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEP 896

Query: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
           +P V+WL+   P++P  R    E + G+  L I    + D G YTC  VN  G     A 
Sbjct: 897 KPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEAR 956

Query: 248 LSIQ 251
           L ++
Sbjct: 957 LEVR 960



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 65/231 (28%), Positives = 100/231 (43%), Gaps = 38/231 (16%)

Query: 24   VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
            V + P + + A + P +++ +  G  A FE  V G  + +V W   G+ +      LL C
Sbjct: 959  VRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA---LLKC 1015

Query: 84   GIR---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
             +        L++ +VHE+D G YTC+ +        +  LTV                 
Sbjct: 1016 KMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV----------------- 1058

Query: 141  GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200
                       RPS+     P F   L  V V EG+  RF CKI+G P P VTW     P
Sbjct: 1059 -----------RPSL----APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCP 1103

Query: 201  LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            ++ S  + + +  G+  L I  V  +D G+Y    VN  G+A  SA+L ++
Sbjct: 1104 MEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F   + D+EV  G  ARF   +EG P P+++W+KD+  + ES H    Y+E+  CSL+
Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN-ECSLV 1543

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1862
            +      D   YTC A N  GE +C AEL V   +T  E EG GE+E+
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED 1591



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 1/97 (1%)

Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
            +P + P F++ + D+EV+EG AARFDCKI G P P V W      + ES + ++  D  G
Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GG 1117

Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              SL I+ V  +D+  Y   AVN+ G+A C+A+L VE
Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 59/230 (25%), Positives = 85/230 (36%), Gaps = 37/230 (16%)

Query: 29   LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH--RNGQPITSGGRFLLDCGIR 86
            L EAPA +  P  + + EG  A        + E QV W   R        G + L     
Sbjct: 1386 LEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDD 1444

Query: 87   GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
              + L I  V   D G  TC A N  G +  +V L +  +                    
Sbjct: 1445 DQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------------------- 1484

Query: 147  PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
                          P+F + +  V V  G+  RF+  + G+P P + W K  V L  S+ 
Sbjct: 1485 --------------PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSH 1530

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256
            VS   +     L +      D GVYTC   N +G+ S  AEL++    +A
Sbjct: 1531 VSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTA 1580



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 47/165 (28%), Positives = 71/165 (43%), Gaps = 18/165 (10%)

Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ--PIQYARSTCEAGVAELHI 570
           AP F   LK+ AV  G D  L+  V GTP P + W  +GQ  P      +C      L +
Sbjct: 42  APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC------LWL 95

Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
           +    +D G Y+C+A+N  G+ SC A +TV E   S  +E    ++  + T  + L+   
Sbjct: 96  RRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAED--DISDVQGTQRLELRDDG 153

Query: 631 DLKVMDGSQVTMT--------VQVSGNPPPEVIWLHNGNEIQESE 667
                 G   T+           V+G    +V W  +G  + E E
Sbjct: 154 AFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQE 198



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 52/252 (20%), Positives = 87/252 (34%), Gaps = 47/252 (18%)

Query: 1088 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF-IIL 1146
            E R+  +  + A    LQDV V  G+  L +C V+      + W   G+ L+       +
Sbjct: 958  EVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKM 1017

Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
              +G  C + +     +D G+Y C       +  CS ++TV                   
Sbjct: 1018 HFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV------------------- 1058

Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
                                      + ++ P   +  ED +V  G +     K++GT P
Sbjct: 1059 --------------------------RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPP 1092

Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1326
               TW  F   ++ESE++++        L I     E  G Y +   N  G       L 
Sbjct: 1093 PVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL- 1151

Query: 1327 VVDKPDPPAGTP 1338
             V++P   A  P
Sbjct: 1152 YVEEPRTAASGP 1163



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%)

Query: 1720 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1779
            K     PTSP    +LES +D   +     A E+P   P F   ++++ V  G+     C
Sbjct: 693  KGRRARPTSP----ELESSDDSYVS-----AGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743

Query: 1780 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             I   P P+V W KD  ++R      +  + + + +L++ +    D   Y   A N LG+
Sbjct: 744  IITANPPPQVSWHKDGSALRSEGRLLLRAEGERH-TLLLREARAADAGSYMATATNELGQ 802

Query: 1840 ATCTAELIV 1848
            ATC A L V
Sbjct: 803  ATCAASLTV 811



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 13/228 (5%)

Query: 972  PPPKPATPDFRSVLG--GKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 1029
            PPP+ +     S L   G+  L AE    +     A+A ++   ++ A        +G A
Sbjct: 749  PPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATAT-----NELGQA 803

Query: 1030 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1089
              A +L      +P  +  P  +    +    +  EE  +  +            + N +
Sbjct: 804  TCAASL----TVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRR 859

Query: 1090 RSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
             S++   AP  FK  L D  V EG+ +++  +V  +P   + W  N + ++  +     +
Sbjct: 860  SSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEE 919

Query: 1149 -EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
             EG LC + I  A   D G Y C A N+ G  +C  ++ V   P S +
Sbjct: 920  AEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRS 967



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 32/96 (33%), Positives = 42/96 (43%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F  ++ D  V EG       +++G P P V W ++ Q +R  +    +  E G C L 
Sbjct: 869  PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
            I      D   YTCKAVN  G   C A L V    E
Sbjct: 929  ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 7/96 (7%)

Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
           AP+FL+ L +  V  GS V + V VSG P P + W  +G  +                L 
Sbjct: 42  APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAP-------EPSCLW 94

Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
           ++    +D G Y+C A N  G    +AVLTV E  D
Sbjct: 95  LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGD 130



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 41/188 (21%), Positives = 74/188 (39%), Gaps = 4/188 (2%)

Query: 343  SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA---TFPTRQPGLGSQDVVSKAA 399
            + +  QA    P   + G    + SG      +  R     + P +  GL   ++ +   
Sbjct: 2509 NQLAAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQ 2568

Query: 400  NRRIPMEGQRDSAFPK-FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQE 458
                    + +S FP  F  K + Q + E +     C  +  P P ++W  +   +R + 
Sbjct: 2569 EELGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEP 2628

Query: 459  GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518
              I V    G   L + +A  R +G Y C+A+N  G ++ S T+ V R+      P    
Sbjct: 2629 SVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQ 2688

Query: 519  VLKDCAVI 526
              +D A++
Sbjct: 2689 TYQDTALV 2696



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 51/178 (28%), Positives = 79/178 (44%), Gaps = 14/178 (7%)

Query: 1017 AQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSASKEELKKDVKND 1074
            A  +G   P   +  +E     G++ P E+   +  G ++P ++ K  S   L   V+ +
Sbjct: 2512 AAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKD-KGLSPPNLSASVQEE 2570

Query: 1075 VNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN 1134
            +    GH        RSES    P F  KL+D  + EG+   L C  ++ P   I W  +
Sbjct: 2571 L----GHQYV-----RSESD-FPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKD 2620

Query: 1135 GKTLKTT-KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
             K+L++    II+S +     +SI +A     GLY+C A N  G    SC V V   P
Sbjct: 2621 KKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 55/209 (26%), Positives = 80/209 (38%), Gaps = 45/209 (21%)

Query: 368 GEERKRPAPPRPATFPTR-QPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVK 426
           GE+    APP P   P R + G G    V+ A               P F    ++  V 
Sbjct: 9   GEDAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGA-------------PVFLRPLKNAAVC 55

Query: 427 ENQTVKFRCEVSGIPKPEVAWFLEGT--PVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
               V+ R  VSG P+P + WF +G   P    E S           L L +   +D+G 
Sbjct: 56  AGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC----------LWLRRCGAQDAGV 105

Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIE------------GQDFV 532
           YSC A N +G+ SC   L V  +   E A    S ++    +E            G D +
Sbjct: 106 YSCMAQNERGRASCEAVLTVLEVGDSETAEDDISDVQGTQRLELRDDGAFSTPTGGSDTL 165

Query: 533 L-------QCSVRGTPVPRITWLLNGQPI 554
           +         SV GT   +++W  +GQ +
Sbjct: 166 VGTSLDTPPTSVTGTSEEQVSWWGSGQTV 194



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 26/94 (27%), Positives = 43/94 (45%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            AP F+  ++DV V  G+       V   P   I+W  +   L  +  +    E + CS+ 
Sbjct: 1484 APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLV 1543

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1190
            +     +D G+Y C A+N AG+  C  ++ V  A
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%)

Query: 1699 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES-EEDVSQAFLEAVAEEKPHVK 1757
            +AV   G+    A +     R +++G P+S L  EK+ S  E+  Q  LE ++       
Sbjct: 1137 SAVNTHGQAHCSAQLYVEEPRTAASG-PSSKL--EKMPSIPEEPEQGELERLSI------ 1187

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F + ++DLEV     A  +C++ G P P + WF +   I+ S   ++    D +  L+
Sbjct: 1188 PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLV 1246

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
               V       Y     N LG+A C A L V  +  G  +G
Sbjct: 1247 FPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDG 1287



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 26/85 (30%), Positives = 43/85 (50%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            ++D++V  G  A F+C + G  D EV W    + ++ +      + +   C L+++ V  
Sbjct: 974  LQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 1033

Query: 1824 DDDAKYTCKAVNSLGEATCTAELIV 1848
            DD   YTCK   +  E TC+A L V
Sbjct: 1034 DDSGVYTCKLSTAKDELTCSARLTV 1058



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 7/124 (5%)

Query: 129  KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
            K L  P +S ++ +      V +      + PP F  KL   V+ EG+     C     P
Sbjct: 2556 KGLSPPNLSASVQEELGHQYVRSE----SDFPPVFHIKLKDQVLLEGEAATLLCLPAACP 2611

Query: 189  QPQVTWLKGNVPL--QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
             P ++W+K    L  +PS  + VS K+G Q+L I    +   G+Y C   N  G  + S 
Sbjct: 2612 APHISWMKDKKSLRSEPSV-IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670

Query: 247  ELSI 250
             +++
Sbjct: 2671 TVAV 2674



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 12/106 (11%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F + +++  V  GS  R    + G P P + WF+D Q +            + +C  +
Sbjct: 43   PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA-------PEPSCLWL 95

Query: 1818 ISDVCGDDDA-KYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
                CG  DA  Y+C A N  G A+C A L V  +E G+ E  E++
Sbjct: 96   RR--CGAQDAGVYSCMAQNERGRASCEAVLTV--LEVGDSETAEDD 137



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%)

Query: 514  PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS----TCEAGVAELH 569
            P F   LKD  ++EG+   L C     P P I+W+ + + ++   S    +C+ G   L 
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643

Query: 570  IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            I  A     G Y C A N LG ++ S  V V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 7/101 (6%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            AP F + L++  V  G  + L+  VS  P  ++ W  +G+ L        + E S   + 
Sbjct: 42   APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAP-----APEPSC--LW 94

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1197
            + +   +D G+Y C+A+N+ G+A C   +TV +   SE  +
Sbjct: 95   LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAE 135



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 5/103 (4%)

Query: 26   SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR--FLLDC 83
            ++ L EAP F     ++ +  G TA+F   V G P P + W+++   +T      F+ + 
Sbjct: 1478 TLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE- 1536

Query: 84   GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
                  SLV+ +   +D G YTC A N +G      EL V  +
Sbjct: 1537 --ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 28/91 (30%), Positives = 38/91 (41%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F   ++D  ++EG AA   C     P P + W KD +S+R      I   +DG   L 
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            I          Y C A N LG  T +  + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 8/92 (8%)

Query: 32  APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
           AP F+ P +N  +  G+  +    V G P+P + W R+GQ        LL         L
Sbjct: 42  APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQ--------LLPAPAPEPSCL 93

Query: 92  VIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
            +     +D G Y+C A N  G       LTV
Sbjct: 94  WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 60/258 (23%), Positives = 101/258 (39%), Gaps = 21/258 (8%)

Query: 1176 AGQAECSCQVTVDDAPASENTKAP-EMKSR---------RPKSSLPPVLGTESDATVKKK 1225
            AG    S +    +A A+  + AP E +SR         + K   PP L     A+V+++
Sbjct: 2515 AGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLS----ASVQEE 2570

Query: 1226 PAPK-TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
               +    ++  PP      +DQ +  GE+  L            +WMK +K ++    +
Sbjct: 2571 LGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSV 2630

Query: 1285 KVENSENGSKL-TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             + + ++G +L +I  A + H G Y     N LGS  +   + V   P   A        
Sbjct: 2631 IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTY 2690

Query: 1344 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKF 1402
            + ++L L   G S     A  +Y++E        W  +++      +NV  L      +F
Sbjct: 2691 QDTALVLWKPGDS----RAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRF 2746

Query: 1403 RVRAINVYGTSEPSQESE 1420
            RV   N  G    S  SE
Sbjct: 2747 RVACANRAGQGPFSNSSE 2764



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 26/93 (27%), Positives = 36/93 (38%)

Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294
            A  P+     ED +V AGE+      V G       W K    + ES H+     EN   
Sbjct: 1482 AEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS 1541

Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            L +L+   +  G YT   +N  G    +  L V
Sbjct: 1542 LVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1574



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 9/91 (9%)

Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLE 219
           P F   L    V  G   R    ++G PQP + W + G +   P+   S         L 
Sbjct: 43  PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC--------LW 94

Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
           +      D GVY+C+  N  G+AS  A L++
Sbjct: 95  LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 8/89 (8%)

Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
           P F+   ++     G  V +   ++G P P++ W RDG+ L             +   L 
Sbjct: 43  PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA--------PEPSCLW 94

Query: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSL 809
           L++     AG Y  + +N  G  SC+  L
Sbjct: 95  LRRCGAQDAGVYSCMAQNERGRASCEAVL 123



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
            P F  K +      G++  + C  A  P P + W++D K+L  +     V   +    L 
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643

Query: 781  LKKVQPWHAGQYEILLKNRVGE--CSCQVSL 809
            + +    HAG YE    N +G    SC V++
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 30/141 (21%), Positives = 54/141 (38%), Gaps = 20/141 (14%)

Query: 1219 DATVKKKPAPKTPPKAAM-------------PPQIIQFPEDQKVRAGESVELFGKVTGTQ 1265
            DA  +  P+P  PPK A               P  ++  ++  V AG  V L   V+GT 
Sbjct: 11   DAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTP 70

Query: 1266 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1325
              +  W +  + +          +   S L +     +  G Y+ + +N+ G    +  L
Sbjct: 71   QPSLRWFRDGQLLPAP-------APEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVL 123

Query: 1326 TVVDKPDPPAGTPCASDIRSS 1346
            TV++  D        SD++ +
Sbjct: 124  TVLEVGDSETAEDDISDVQGT 144



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 13/101 (12%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH--FQIDYDEDGNCSLIISDVCGDDD 1826
            VVEG  A        + + +VVW     ++ E+R   +++   +D    L I  V   D 
Sbjct: 1401 VVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDM 1459

Query: 1827 AKYTCKAVNSLGEATCTA----------ELIVETMEEGEGE 1857
               TC A N  G  TC+           E I+E +E G GE
Sbjct: 1460 GALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE 1500



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 1/91 (1%)

Query: 623  PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 681
            P+F   L D  +++G   T+    +  P P + W+ +   ++ E        +  +  L 
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643

Query: 682  IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            I        G Y C A N  G + +   + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score =  185 bits (469), Expect = 4e-46
 Identities = 156/588 (26%), Positives = 244/588 (41%), Gaps = 98/588 (16%)

Query: 1194 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1245
            ENT   E    R+PK  L   +  +   + ++       P  +M    P  IQ   PE  
Sbjct: 2415 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 2474

Query: 1246 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1296
                D     G++V L  KV G    T TW    + I ++++      V + ++G   L 
Sbjct: 2475 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 2534

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356
            I     +  G YT +  N  G+      + V   P  P   P A +   +S+ L W   S
Sbjct: 2535 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 2593

Query: 1357 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
              G   +  Y++E  +  ++ W++ +A+   T   ++DL P   Y+FRV A N +G S P
Sbjct: 2594 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 2653

Query: 1416 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1473
            S+ SE   +                    PE D      TI+ ++     Y     +G G
Sbjct: 2654 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 2693

Query: 1474 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1533
            +F  V + + K TRK  A KF      K+KE    E +++  L HP+ +   D +E   +
Sbjct: 2694 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 2752

Query: 1534 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1593
             +++LE++  G L + +++ D EL E +   Y+R I E ++Y+H   + HLD+KPEN++ 
Sbjct: 2753 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 2811

Query: 1594 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652
              +    R+KLID   A ++     +  L G PEF APEVI   P+   TD+WSIGV+ Y
Sbjct: 2812 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 2871

Query: 1653 IL---------------------------------------------------NRLDCTQ 1661
            ++                                                    R     
Sbjct: 2872 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 2931

Query: 1662 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1709
            CLQHPWL     +     L   R+  ++ RRK Q   N VR I  + S
Sbjct: 2932 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 2976



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%)

Query: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 560
            + EVAP F   L D   + G   +LQC V G P P ITW    Q I         Y  S+
Sbjct: 2466 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 2525

Query: 561  CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620
            C++G   L I + +P+D G YTC+A N  G  S SA V V            +P AP++P
Sbjct: 2526 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 2575

Query: 621  TA 622
             A
Sbjct: 2576 IA 2577



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208
            P+   E  P+F   L  V    G      CK+ GRP+P +TW   +  +      SA  +
Sbjct: 2463 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 2522

Query: 209  VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266
            VS   +G   L+I  +   D G+YTC+  N  G  S SA + +QG+ +A NR   +E   
Sbjct: 2523 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 2582

Query: 267  TNSDVR 272
            T+  +R
Sbjct: 2583 TSVILR 2588



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%)

Query: 998  SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 1056
            S  E +   AV         QP+    P      P   L P+  A  AE+    G+ K  
Sbjct: 2343 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 2400

Query: 1057 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1093
                 L+   + E++   KN         D+   +     T++ + SE            
Sbjct: 2401 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 2460

Query: 1094 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1142
                  Q  AP F   L DV    G  ++LQC+V   P  TI W    + +  T      
Sbjct: 2461 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 2520

Query: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202
            + + S +    ++ I   +P+D G+Y C+A ND G    S  V V   PA+ N    + +
Sbjct: 2521 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 2580

Query: 1203 S 1203
            S
Sbjct: 2581 S 2581



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%)

Query: 598  VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
            V+V E  SS +SE           +L     +  AP FL  L D+  + G  V +  +V 
Sbjct: 2436 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 2495

Query: 648  GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 702
            G P P + W      I ++++       +     + +L I  + P+D+G YTC A N  G
Sbjct: 2496 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 2555

Query: 703  EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 757
               T A + VQ  P    +P  I++ RS T+     L  S   +C I+G    TV +  +
Sbjct: 2556 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 2610

Query: 758  GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
            G  + + +    V    D + LV++ + P    Q+ +   N  G
Sbjct: 2611 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 2649



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87
            AP F++P  ++    G T   + +V G P+P +TW    Q I     S   + +     G
Sbjct: 2470 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 2529

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
              +L I  +  +D G YTC ATN  G    +  + V+G
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 2567



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1811
            V P F   + D+  + G      CK+ G P P + W   DQ+I ++ +    Y     + 
Sbjct: 2469 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 2528

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            G  +L I ++   D   YTC A N  G  + +A + V+
Sbjct: 2529 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 2566



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 430  TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYE----DAGSHYLCLLKARTRDSGTY 485
            TV  +C+V G PKP + W      +   + S   Y     D+G   L +     +DSG Y
Sbjct: 2487 TVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIY 2546

Query: 486  SCTASNAQGQLSCSWTLQVE 505
            +C A+N  G  S S T++V+
Sbjct: 2547 TCIATNDHGTTSTSATVKVQ 2566



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 775
            P F+     VT  LG +V++ C + G P PT+ W    + +  DT +          +  
Sbjct: 2471 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 2529

Query: 776  VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
              TL +  + P  +G Y  +  N  G  S   ++ +Q   A
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 2570


>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
          Length = 1289

 Score =  185 bits (469), Expect = 4e-46
 Identities = 156/588 (26%), Positives = 244/588 (41%), Gaps = 98/588 (16%)

Query: 1194 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1245
            ENT   E    R+PK  L   +  +   + ++       P  +M    P  IQ   PE  
Sbjct: 718  ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 777

Query: 1246 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1296
                D     G++V L  KV G    T TW    + I ++++      V + ++G   L 
Sbjct: 778  VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 837

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356
            I     +  G YT +  N  G+      + V   P  P   P A +   +S+ L W   S
Sbjct: 838  ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 896

Query: 1357 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1415
              G   +  Y++E  +  ++ W++ +A+   T   ++DL P   Y+FRV A N +G S P
Sbjct: 897  STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 956

Query: 1416 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1473
            S+ SE   +                    PE D      TI+ ++     Y     +G G
Sbjct: 957  SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 996

Query: 1474 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1533
            +F  V + + K TRK  A KF      K+KE    E +++  L HP+ +   D +E   +
Sbjct: 997  RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 1055

Query: 1534 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1593
             +++LE++  G L + +++ D EL E +   Y+R I E ++Y+H   + HLD+KPEN++ 
Sbjct: 1056 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 1114

Query: 1594 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1652
              +    R+KLID   A ++     +  L G PEF APEVI   P+   TD+WSIGV+ Y
Sbjct: 1115 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 1174

Query: 1653 IL---------------------------------------------------NRLDCTQ 1661
            ++                                                    R     
Sbjct: 1175 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 1234

Query: 1662 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1709
            CLQHPWL     +     L   R+  ++ RRK Q   N VR I  + S
Sbjct: 1235 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 1279



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%)

Query: 509 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 560
           + EVAP F   L D   + G   +LQC V G P P ITW    Q I         Y  S+
Sbjct: 769 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 828

Query: 561 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 620
           C++G   L I + +P+D G YTC+A N  G  S SA V V            +P AP++P
Sbjct: 829 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 878

Query: 621 TA 622
            A
Sbjct: 879 IA 880



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)

Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208
           P+   E  P+F   L  V    G      CK+ GRP+P +TW   +  +      SA  +
Sbjct: 766 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 825

Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266
           VS   +G   L+I  +   D G+YTC+  N  G  S SA + +QG+ +A NR   +E   
Sbjct: 826 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 885

Query: 267 TNSDVR 272
           T+  +R
Sbjct: 886 TSVILR 891



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%)

Query: 998  SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 1056
            S  E +   AV         QP+    P      P   L P+  A  AE+    G+ K  
Sbjct: 646  SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 703

Query: 1057 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1093
                 L+   + E++   KN         D+   +     T++ + SE            
Sbjct: 704  CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 763

Query: 1094 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1142
                  Q  AP F   L DV    G  ++LQC+V   P  TI W    + +  T      
Sbjct: 764  LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 823

Query: 1143 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1202
            + + S +    ++ I   +P+D G+Y C+A ND G    S  V V   PA+ N    + +
Sbjct: 824  YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 883

Query: 1203 S 1203
            S
Sbjct: 884  S 884



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%)

Query: 598 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
           V+V E  SS +SE           +L     +  AP FL  L D+  + G  V +  +V 
Sbjct: 739 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 798

Query: 648 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 702
           G P P + W      I ++++       +     + +L I  + P+D+G YTC A N  G
Sbjct: 799 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 858

Query: 703 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 757
              T A + VQ  P    +P  I++ RS T+     L  S   +C I+G    TV +  +
Sbjct: 859 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 913

Query: 758 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
           G  + + +    V    D + LV++ + P    Q+ +   N  G
Sbjct: 914 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 952



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)

Query: 32  APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87
           AP F++P  ++    G T   + +V G P+P +TW    Q I     S   + +     G
Sbjct: 773 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 832

Query: 88  TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
             +L I  +  +D G YTC ATN  G    +  + V+G
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 870



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1811
            V P F   + D+  + G      CK+ G P P + W   DQ+I ++ +    Y     + 
Sbjct: 772  VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 831

Query: 1812 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            G  +L I ++   D   YTC A N  G  + +A + V+
Sbjct: 832  GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 869



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 26/80 (32%), Positives = 39/80 (48%), Gaps = 4/80 (5%)

Query: 430 TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYE----DAGSHYLCLLKARTRDSGTY 485
           TV  +C+V G PKP + W      +   + S   Y     D+G   L +     +DSG Y
Sbjct: 790 TVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIY 849

Query: 486 SCTASNAQGQLSCSWTLQVE 505
           +C A+N  G  S S T++V+
Sbjct: 850 TCIATNDHGTTSTSATVKVQ 869



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%)

Query: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 775
           P F+     VT  LG +V++ C + G P PT+ W    + +  DT +          +  
Sbjct: 774 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 832

Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 816
             TL +  + P  +G Y  +  N  G  S   ++ +Q   A
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 873


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score =  179 bits (454), Expect = 2e-44
 Identities = 185/766 (24%), Positives = 292/766 (38%), Gaps = 155/766 (20%)

Query: 53   EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
            E R  G P PQ+ W +NG P+       L     G    ++ A    D   YTC A+N +
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSSHIRLLAA--GQVIRIVRA-QVSDVAVYTCVASNRA 3419

Query: 113  GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG--RV 170
            G       L V   FA                               PP     +G   +
Sbjct: 3420 GVDNKHYNLQV---FA-------------------------------PPNMDNSMGTEEI 3445

Query: 171  VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             V +G     +C   G P P + WL+   PL   A ++VS  +GM VL++     +D G 
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST-HGM-VLQLLKAETEDSGK 3503

Query: 231  YTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
            YTC+  N +G+ S    L +          +       S+  +E++ +++   +L  +  
Sbjct: 3504 YTCIASNEAGEVSKHFILKV----------LEPPHINGSEEHEEISVIVNNPLELTCI-- 3551

Query: 291  AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
                               A+  P P    K+   KD  R  PQT  +Q       L+ +
Sbjct: 3552 -------------------ASGIPAP----KMTWMKDG-RPLPQTDQVQTLGGGEVLRIS 3587

Query: 351  RVQPEPRAPGLGVLS-PSGEERKRPAPPRPATFPTR---QPGLGSQDVVSKAANRRIPME 406
              Q E       + S P+G++ K         +  R    P +   D             
Sbjct: 3588 TAQVEDTGRYTCLASSPAGDDDKE--------YLVRVHVPPNIAGTD------------- 3626

Query: 407  GQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYED 466
                        +P+   V  N+ V   C+   +P P + W   G    R + +  V   
Sbjct: 3627 ------------EPRDITVLRNRQVTLECKSDAVPPPVITWLRNG---ERLQATPRVRIL 3671

Query: 467  AGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI 526
            +G  YL +  A   D+  Y+C ASN  G+ +  + L V       V P+     +   ++
Sbjct: 3672 SGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVN------VPPNIKGGPQSLVIL 3725

Query: 527  EGQDFVLQCSVRGTPVPRITWLLNGQPI--QYAR-STCEAGVAELHIQDALPEDHGTYTC 583
              +  VL+C   G P PRITW  +G  +   +AR S  E G   LHIQ A   D G Y C
Sbjct: 3726 LNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF--LHIQSAHVTDTGRYLC 3783

Query: 584  LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
            +A NA G                R+ +  + V PS    P      +++ V+   Q T+ 
Sbjct: 3784 MATNAAGT-------------DRRRIDLQVHVPPSIAPGP------TNMTVIVNVQTTLA 3824

Query: 644  VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             + +G P P + W  NG+ +   ++ +  +  +  SL I     +DT TY C   N AG+
Sbjct: 3825 CEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTNGAGD 3884

Query: 704  VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
             +    LTVQ P     P    +P     +     +I+C  +G PFP++HW ++G  L  
Sbjct: 3885 DKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLP 3939

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
                + +L +  +  L     Q  HAG+Y  + +N  G     V+L
Sbjct: 3940 RGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHRHVTL 3982



 Score =  152 bits (385), Expect = 2e-36
 Identities = 185/803 (23%), Positives = 298/803 (37%), Gaps = 129/803 (16%)

Query: 60   PEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            P P +TW ++G P+       +         L I     +D G+YTCEATN +G  +   
Sbjct: 2131 PPPTLTWLKDGHPLLKKPGLSIS---ENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNY 2187

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             + +                             P+I G      + +L ++ V EG +  
Sbjct: 2188 NVNIW--------------------------VPPNIGG------SDELTQLTVIEGNLIS 2215

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
              C+ +G P P + W K   P+   +   V   +G + L+I    + D  +Y+C+  N +
Sbjct: 2216 LLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVA 2275

Query: 240  GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKS----- 294
            G A     L +         ++R T  TNS      T +I    K  SLE   +      
Sbjct: 2276 GTAKKEYNLQV---------YIRPT-ITNSG--SHPTEIIVTRGKSISLECEVQGIPPPT 2323

Query: 295  ---------------------------KNCSSPQRGGSPPWAANSQPQPPRESKLE---- 323
                                       KN      G     A N      ++  L     
Sbjct: 2324 VTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAP 2383

Query: 324  -SCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLG---VLSPSGEERKRPAPPRP 379
             S   + R+     V++K S S+T +A+ + P P          +S S   R        
Sbjct: 2384 PSIIGNHRSPENISVVEKNSVSLTCEASGI-PLPSITWFKDGWPVSLSNSVRILSGGRML 2442

Query: 380  ATFPTRQPGLGSQD-VVSKAANRRIPMEGQRDSAFPKF--ESKPQSQEVKENQTVKFRCE 436
                T     G    VV  AA     + G      P    E+  +  +VKE Q+V   CE
Sbjct: 2443 RLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCE 2502

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
            V+G P PE+ W  +G P++  E    +   +G  +L +   +   +G Y+C AS+  G  
Sbjct: 2503 VTGNPVPEITWHKDGQPLQEDEAHHII---SGGRFLQITNVQVPHTGRYTCLASSPAGHK 2559

Query: 497  SCSWTLQVERLAVMEVAPSFSSV-----LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551
            S S++L V       V+P+ + V      +D  VI      L C     P   ITW  +G
Sbjct: 2560 SRSFSLNV------FVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDG 2613

Query: 552  QPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
             P++  R+     G   L I +A  ++ G Y+C+A N  G++     V V+      K +
Sbjct: 2614 TPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGD 2673

Query: 611  YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 670
               P    K           ++K+   + +T+  +    P   + W  +G  ++  +  +
Sbjct: 2674 LWGPGLSPK-----------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVN 2722

Query: 671  FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS----- 725
                G  H+L I+E    DTG YTC A N AGE      + +Q P    + W I      
Sbjct: 2723 IAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDT 2780

Query: 726  --KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
                 +    +   + + C     P PT+ W +DG  L   T   +VL       L + +
Sbjct: 2781 GRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPL---TSSDKVLILPGGRVLQIPR 2837

Query: 784  VQPWHAGQYEILLKNRVGECSCQ 806
             +   AG+Y  +  N  GE S Q
Sbjct: 2838 AKVEDAGRYTCVAVNEAGEDSLQ 2860



 Score =  152 bits (383), Expect = 4e-36
 Identities = 185/775 (23%), Positives = 275/775 (35%), Gaps = 135/775 (17%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGRFLLDCGIRGTFSL 91
            P FI  P ++ ++ G+       V+GYPEP + W R +  PI S    +       T +L
Sbjct: 793  PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 92   VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
             I  +   D+G Y CEA N  G  Q    +TV G                    AP +  
Sbjct: 853  FILNLWASDKGTYICEAENQFGKIQSETTVTVTG------------------LVAPLIGI 894

Query: 152  RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI-TGRPQPQVTWLKGNVPLQPSARVSVS 210
             PS+                V EGQ     C +  G P P+  W+K +  L  +  ++V 
Sbjct: 895  SPSVAN--------------VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR 940

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
                   L I  V   D G YTC+  N +G  + +  + +  L +               
Sbjct: 941  SDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHG----------- 986

Query: 271  VRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR 330
                       +  L ++E    +  C            A+  P+P              
Sbjct: 987  -----------QQILSTIEGIPVTLPCK-----------ASGNPKP-------------- 1010

Query: 331  TAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390
                + +  K    I+  +A+         L V+SP GEE             T   G  
Sbjct: 1011 ----SVIWSKKGELISTSSAKFSAGADG-SLYVVSPGGEESGEYV-----CTATNTAGYA 1060

Query: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
             + V      R      QR  +    + KP    V   + V   CEV  +P P + W  E
Sbjct: 1061 KRKVQLTVYVRPRVFGDQRGLS----QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE 1116

Query: 451  GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
             T +         +  +GS  + + + RT DSG Y C A+N  G ++ +  L V      
Sbjct: 1117 -TQLISPFSPRHTFLPSGS--MKITETRTSDSGMYLCVATNIAGNVTQAVKLNVH----- 1168

Query: 511  EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAELH 569
             V P      K   V  GQ   + C+ +GTP+P ITW   G  +              L 
Sbjct: 1169 -VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS 1227

Query: 570  IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 629
            I  A P D G YTC+A N  G       + V E  +    E         P    F + +
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLE--------PPYNTTFQERV 1279

Query: 630  SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHFEQRGTQHSLCIQEVFPE 688
            ++       ++       G P P + WLHNG E+   E      + GT   L I  V P 
Sbjct: 1280 AN------QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT--LLVIASVTPY 1331

Query: 689  DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR--SVTASLGQSVLISCAIAG 746
            D G Y C A N AG    +  L V  P     P    K +  +V+  L Q   + C + G
Sbjct: 1332 DNGEYICVAVNEAGTTERKYNLKVHVP-----PVIKDKEQVTNVSVLLNQLTNLFCEVEG 1386

Query: 747  DPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
             P P + W +D   +  ++   + + N  +  L L +  P  AG+Y     N  G
Sbjct: 1387 TPSPIIMWYKDNVQV-TESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAG 1438



 Score =  149 bits (376), Expect = 2e-35
 Identities = 189/804 (23%), Positives = 285/804 (35%), Gaps = 137/804 (17%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            PR++ +        E +    P P +TW RNG+ + +  R  +  G R    L I+    
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGR---YLQINNADL 3684

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
             D   YTC A+N +G       LTV                             P+I G 
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILTVN--------------------------VPPNIKGG 3718

Query: 159  CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS-ARVSVSEKNGMQV 217
             P      L +  V E       C   G P P++TW K    L  + AR S+ E NG   
Sbjct: 3719 -PQSLVILLNKSTVLE-------CIAEGVPTPRITWRKDGAVLAGNHARYSILE-NGF-- 3767

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ-------------------------- 251
            L I   +  D G Y C+  N +G      +L +                           
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEA 3827

Query: 252  -GLDSANRSFVRETKATNSDVRKEVTNVISKESKL---DSLEAAAKSKNCSSPQRGGSPP 307
             G+   + ++ +     N D  +    ++S  S +    S++  A +  C+     G   
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTA-TYECTVTNGAGDDK 3886

Query: 308  WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAAR-----VQPEPRAPGLG 362
               +   Q P  S  +   D   T     V+  T+S +   +       ++  PR  G  
Sbjct: 3887 RTVDLTVQVP-PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR 3945

Query: 363  VLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK----AANRRIPMEGQRDSAFPKFES 418
            +LS    E             T+    G    V++    +A+R + +        P  + 
Sbjct: 3946 ILSSGAIE----------ILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP---PVIQP 3992

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            +P    V  N  +   CE +G P P + W  EG  V     +  V    G   L + +A 
Sbjct: 3993 QPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAV 4049

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
              D+GTY C A N  G       L V+      V P  S  LK+  +   +   L C   
Sbjct: 4050 REDAGTYMCVAQNPAGTALGKIKLNVQ------VPPVISPHLKEYVIAVDKPITLSCEAD 4103

Query: 539  GTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWV 598
            G P P ITW  +G+ I  +          L I    P D G YTC+A N  G  S S  +
Sbjct: 4104 GLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163

Query: 599  TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
            TVH     R +E                       V + SQ  +     G P P + W  
Sbjct: 4164 TVHVPPRIRSTE-------------------GHYTVNENSQAILPCVADGIPTPAINWKK 4204

Query: 659  NGNEIQE-SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
            +   +      +  E  G    L ++ V  ED+G YTC A N+AGE      LTV     
Sbjct: 4205 DNVLLANLLGKYTAEPYG---ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVH---- 4257

Query: 718  GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 777
               P F   P  V+ + G+ + +SC   G P P + W  +   +     HF+ +      
Sbjct: 4258 -VLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII---PAHFDSVNGHS-- 4311

Query: 778  TLVLKKVQPWHAGQYEILLKNRVG 801
             LV+++V    +G Y    +N VG
Sbjct: 4312 ELVIERVSKEDSGTYVCTAENSVG 4335



 Score =  149 bits (375), Expect = 3e-35
 Identities = 119/423 (28%), Positives = 179/423 (42%), Gaps = 42/423 (9%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+  S      V EN      C   GIP P + W  +   +    G     E  G   L 
Sbjct: 4169 PRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTA-EPYGE--LI 4225

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L      DSG Y+C A+NA G+ + + +L V       V P+F+ +  D ++ +G+   L
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVH------VLPTFTELPGDVSLNKGEQLRL 4279

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             C   G P+P++TW  N   I  A      G +EL I+    ED GTY C AEN++G V 
Sbjct: 4280 SCKATGIPLPKLTWTFNNNIIP-AHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVK 4338

Query: 594  CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
               +V V E     K +Y     PS    P+            G    +  +V G+P P 
Sbjct: 4339 AIGFVYVKEPPVF-KGDY-----PSNWIEPL------------GGNAILNCEVKGDPTPT 4380

Query: 654  VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
            + W   G +I+ S   H  ++    SL I     ED G YTC A N AG V     LT+Q
Sbjct: 4381 IQWNRKGVDIEIS---HRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437

Query: 714  EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN 773
             P     P    +P     + G  ++++C   G+P PT+ W R G ++  D     VL N
Sbjct: 4438 SP-----PIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWD-DRVNVLSN 4491

Query: 774  EDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCG 833
                +L +   Q     ++E + +N +G    +V +++Q        +     +C   CG
Sbjct: 4492 N---SLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHG--GFSQWSAWRACSVTCG 4546

Query: 834  GGV 836
             G+
Sbjct: 4547 KGI 4549



 Score =  144 bits (364), Expect = 6e-34
 Identities = 110/403 (27%), Positives = 171/403 (42%), Gaps = 41/403 (10%)

Query: 414  PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSH- 470
            P  ++   ++E+   +  +    C   G P P +AW  +G P+      ++ +    +H 
Sbjct: 3434 PNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPL-----GLDAHLTVSTHG 3488

Query: 471  -YLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ 529
              L LLKA T DSG Y+C ASN  G++S  + L+V    +     + S   ++ +VI   
Sbjct: 3489 MVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKV----LEPPHINGSEEHEEISVIVNN 3544

Query: 530  DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENA 588
               L C   G P P++TW+ +G+P+         G  E L I  A  ED G YTCLA + 
Sbjct: 3545 PLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSP 3604

Query: 589  LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
             G       V VH           +P   +    P       D+ V+   QVT+  +   
Sbjct: 3605 AGDDDKEYLVRVH-----------VPPNIAGTDEP------RDITVLRNRQVTLECKSDA 3647

Query: 649  NPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
             PPP + WL NG  +Q +        G    L I      DT  YTC A N AG+   + 
Sbjct: 3648 VPPPVITWLRNGERLQATPRVRILSGG--RYLQINNADLGDTANYTCVASNIAGKTTREF 3705

Query: 709  VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 768
            +LTV  P     P     P+S+   L +S ++ C   G P P + W +DG  L  +   +
Sbjct: 3706 ILTVNVP-----PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARY 3760

Query: 769  EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             +L+N     L ++       G+Y  +  N  G    ++ L +
Sbjct: 3761 SILENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800



 Score =  139 bits (351), Expect = 2e-32
 Identities = 106/390 (27%), Positives = 171/390 (43%), Gaps = 43/390 (11%)

Query: 420  PQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479
            P    V  N+ V   C+V G P P++ WF +G P+   + ++E+ +      L L  AR 
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--QVLHLKNARR 1517

Query: 480  RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS--SVLKDCAVIEGQDFVLQCSV 537
             D G Y CT SNA G+ +    L +       + PS    +V  D +V+      L+C  
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIY------IPPSIKGGNVTTDISVLINSLIKLECET 1571

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSA 596
            RG P+P ITW  +GQPI  +         + LHI  A   D  TYTC   N  G      
Sbjct: 1572 RGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTA---- 1627

Query: 597  WVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
                  +KS     Y+ P+       P+      + +V+    +T+  + +GNP P + W
Sbjct: 1628 ------EKSFHVDVYVPPMIEGNLATPL------NKQVVIAHSLTLECKAAGNPSPILTW 1675

Query: 657  LHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            L +G  ++ +++   E  G +   +  QE+   D G Y C A + AGE   +  + V  P
Sbjct: 1676 LKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYICVATSVAGEKEIKYEVDVLVP 1732

Query: 716  ---HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
                 G +  +          +   + + C + G P PT+ WL+DG+ + +  G F++L 
Sbjct: 1733 PAIEGGDETSYF------IVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDG-FKILL 1785

Query: 773  NEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
            N     LV+ + Q  + G Y  +  N  G+
Sbjct: 1786 NGR--KLVIAQAQVSNTGLYRCMAANTAGD 1813



 Score =  137 bits (345), Expect = 1e-31
 Identities = 105/389 (26%), Positives = 162/389 (41%), Gaps = 31/389 (7%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P          V  N  V+  CE  GIP P + W  +G+PV      ++V   +G   L 
Sbjct: 2012 PSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVL--SGGRILA 2069

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L  A+  D+G Y+C A NA G+      L+V       V P+     ++ +V+  Q   L
Sbjct: 2070 LTSAQISDTGRYTCVAVNAAGEKQRDIDLRV------YVPPNIMGEEQNVSVLISQAVEL 2123

Query: 534  QCSVRGTPVPRITWLLNGQP-IQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
             C     P P +TWL +G P ++    +     + L I+DA  +D G YTC A N  G+ 
Sbjct: 2124 LCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKT 2183

Query: 593  SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
              +  V +    +   S+                  L+ L V++G+ +++  + SG PPP
Sbjct: 2184 EKNYNVNIWVPPNIGGSD-----------------ELTQLTVIEGNLISLLCESSGIPPP 2226

Query: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
             +IW   G+ +                L I      D   Y+C A N AG  + +  L V
Sbjct: 2227 NLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286

Query: 713  QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
                  T     S P  +  + G+S+ + C + G P PTV W++DG  L K  G  E+L 
Sbjct: 2287 YIRPTITNSG--SHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKG-VEILD 2343

Query: 773  NEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
               +  L LK +     G+Y  +  N  G
Sbjct: 2344 EGHI--LQLKNIHVSDTGRYVCVAVNVAG 2370



 Score =  136 bits (342), Expect = 2e-31
 Identities = 110/392 (28%), Positives = 165/392 (42%), Gaps = 42/392 (10%)

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            K ++  V  N  +   CEVSG P P+++W     P++    ++ V    G   L +++A+
Sbjct: 2970 KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIV---PGGRTLQIIRAK 3026

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSF----SSVLKDCAVIEGQDFVLQ 534
              D G Y+C A N  G+    ++L V       V PS     S  L    V EG    L+
Sbjct: 3027 VSDGGEYTCIAINQAGESKKKFSLTVY------VPPSIKDHDSESLSVVNVREGTSVSLE 3080

Query: 535  CSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCLAENALGQ 591
            C     P P ITW  NG+ I    ST    +A+   LHI+ A   D G Y C A N  G+
Sbjct: 3081 CESNAVPPPVITWYKNGRMI--TESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGR 3138

Query: 592  VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 651
               +  + V+           +P +   P   + ++ +S+        VT+T   +G PP
Sbjct: 3139 DDKNFHLNVY-----------VPPSIEGPEREVIVETISN-------PVTLTCDATGIPP 3180

Query: 652  PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT 711
            P + WL N   I+ S+            L I      D+G YTC A N  G+ +    L+
Sbjct: 3181 PTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS 3240

Query: 712  VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK-DTGHFEV 770
            +Q P           P  V+  LG++V + C   G P P + WL+DGK +   +T    V
Sbjct: 3241 IQVPPSVAG---AEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRV 3297

Query: 771  LQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
              N    TL +        G+Y  +  N  GE
Sbjct: 3298 SANGS--TLNIYGALTSDTGKYTCVATNPAGE 3327



 Score =  135 bits (341), Expect = 3e-31
 Identities = 154/637 (24%), Positives = 236/637 (37%), Gaps = 78/637 (12%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQV 217
            PP        V V  G+    +C I       +TW + +  V L   AR+          
Sbjct: 519  PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--- 575

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-----NRSFVRETK------A 266
            LE+  V  +D G Y C+V +  G ++ S  L++Q          N+SF   ++      A
Sbjct: 576  LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSA 635

Query: 267  TNSDVRKEVTNV-----ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
            T     K    V     +       + +     KN +    G     A+NS     + S 
Sbjct: 636  TGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695

Query: 322  LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
            L    ++P+       L      IT+   +          G+  P  +  K     RP+T
Sbjct: 696  LRYI-EAPKLMVVQSELLVALGDITVMECKTS--------GIPPPQVKWFKGDLELRPST 746

Query: 382  FPTRQPGLG------SQD--------VVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKE 427
            F    P LG      +QD        V    A R          + P F  +P    ++ 
Sbjct: 747  FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEI 806

Query: 428  NQTVKFRCEVSGIPKPEVAWF-LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYS 486
               V   C V G P+P + W  L+  P+  +  S+       +  L +L     D GTY 
Sbjct: 807  GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866

Query: 487  CTASNAQGQLSCSWTLQVERLA--VMEVAPSFSSVLKDCAVIEGQDFVLQCSV-RGTPVP 543
            C A N  G++    T+ V  L   ++ ++PS ++V      IEGQ   L C++  G P+P
Sbjct: 867  CEAENQFGKIQSETTVTVTGLVAPLIGISPSVANV------IEGQQLTLPCTLLAGNPIP 920

Query: 544  RITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
               W+ N   +             LHI+    +D G YTC+A N  G  + +  V VH  
Sbjct: 921  ERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-- 978

Query: 604  KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
                               P    G   L  ++G  VT+  + SGNP P VIW   G  I
Sbjct: 979  -----------------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELI 1021

Query: 664  QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPHDGTQPW 722
              S        G   SL +     E++G Y C A N+AG  + +  LTV   P       
Sbjct: 1022 STSSAKF--SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQR 1079

Query: 723  FIS--KPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 757
             +S  KP  ++   G+ V + C +   P P + W ++
Sbjct: 1080 GLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE 1116



 Score =  135 bits (341), Expect = 3e-31
 Identities = 108/404 (26%), Positives = 173/404 (42%), Gaps = 38/404 (9%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            PK +  P+  +V+  Q V   C   G P P + W   G+ +   +G   V    G+  L 
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML-VDGEHHVSNPDGT--LS 1227

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME-VAPSFSSVLKDCAVIEGQDFV 532
            + +A   D+G Y+C A+N  G      TL V+    +E + P +++  ++   +  Q   
Sbjct: 1228 IDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQER--VANQRIE 1285

Query: 533  LQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
              C  +GTP P I WL NG+ +   +   S  E G   L I    P D+G Y C+A N  
Sbjct: 1286 FPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEA 1344

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G       + VH          + PV   K       + ++++ V+      +  +V G 
Sbjct: 1345 GTTERKYNLKVH----------VPPVIKDK-------EQVTNVSVLLNQLTNLFCEVEGT 1387

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P P ++W  +  ++ ES        G    L +    PED G Y+C+A N AG  +    
Sbjct: 1388 PSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRATPEDAGRYSCKAINIAGTSQKYFN 1445

Query: 710  LTVQEPHDGTQPWFISK--PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
            + V  P     P  I    P  V+  L + V + C + G PFP +HW +DGK L     +
Sbjct: 1446 IDVLVP-----PTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPN 1500

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             E+L    V  L LK  +    G+Y+  + N  G+ +  + L +
Sbjct: 1501 VELLDRGQV--LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score =  125 bits (314), Expect = 4e-28
 Identities = 101/388 (26%), Positives = 156/388 (40%), Gaps = 38/388 (9%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V  N  ++  C V+G P P + W  +G  +  ++G   +        L + +A+  ++G 
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGL 1802

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSF-SSVLKDCAVIEGQDFVLQCSVRGTPVP 543
            Y C A+N  G     + + V       V P+  SS L +  V++ +   LQC   G P P
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVH------VPPTIKSSGLSERVVVKYKPVALQCIANGIPNP 1856

Query: 544  RITWLLNGQPIQYARST--CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 601
             ITWL + QP+  A+     ++    L I   L ED G YTC+A NA G+      + VH
Sbjct: 1857 SITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVH 1916

Query: 602  EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 661
            E  S   +  +L                 +  V+  + V +  + +GNP P + W  +  
Sbjct: 1917 EPPSLEDAGKML-----------------NETVLVSNPVQLECKAAGNPVPVITWYKDNR 1959

Query: 662  EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
             +  S    F  RG    + I+     D G Y C A NSAG       L V        P
Sbjct: 1960 LLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGATELFYSLQVH-----VAP 2012

Query: 722  WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
                    V   +   V + C   G P P++ WL+DG  +   +   +VL    +  L L
Sbjct: 2013 SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRI--LAL 2070

Query: 782  KKVQPWHAGQYEILLKNRVGECSCQVSL 809
               Q    G+Y  +  N  GE    + L
Sbjct: 2071 TSAQISDTGRYTCVAVNAAGEKQRDIDL 2098



 Score =  119 bits (298), Expect = 3e-26
 Identities = 97/386 (25%), Positives = 155/386 (40%), Gaps = 34/386 (8%)

Query: 420  PQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479
            P    V   + V+  C  +GIP P + W  +G P+   E    +   A    L +  A T
Sbjct: 3253 PSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETE-RIRVSANGSTLNIYGALT 3311

Query: 480  RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 539
             D+G Y+C A+N  G+    + L V    V           +    +      ++C   G
Sbjct: 3312 SDTGKYTCVATNPAGEEDRIFNLNVY---VTPTIRGNKDEAEKLMTLVDTSINIECRATG 3368

Query: 540  TPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQVSCSAWV 598
            TP P+I WL NG P+  +         + + I  A   D   YTC+A N  G        
Sbjct: 3369 TPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG-------- 3420

Query: 599  TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 658
                     K   L   AP      +   G  ++ V+ GS  +M     G P P + WL 
Sbjct: 3421 ------VDNKHYNLQVFAPPNMDNSM---GTEEITVLKGSSTSMACITDGTPAPSMAWLR 3471

Query: 659  NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH-- 716
            +G  +    D H         L + +   ED+G YTC A N AGEV    +L V EP   
Sbjct: 3472 DGQPL--GLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHI 3529

Query: 717  DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
            +G++     +   ++  +   + ++C  +G P P + W++DG+ L   T   + L   +V
Sbjct: 3530 NGSE-----EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL-PQTDQVQTLGGGEV 3583

Query: 777  FTLVLKKVQPWHAGQYEILLKNRVGE 802
              +   +V+    G+Y  L  +  G+
Sbjct: 3584 LRISTAQVE--DTGRYTCLASSPAGD 3607



 Score =  119 bits (297), Expect = 4e-26
 Identities = 108/402 (26%), Positives = 156/402 (38%), Gaps = 48/402 (11%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P     P +  V  N      CE +GIPKP + W   G  +   +     Y    S  L 
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQ-NSYRLLSSGSLV 3862

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            ++     D+ TY CT +N  G    +  L V      +V PS +    D  V +    V+
Sbjct: 3863 IISPSVDDTATYECTVTNGAGDDKRTVDLTV------QVPPSIADEPTDFLVTKHAPAVI 3916

Query: 534  QCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDH-GTYTCLAENAL 589
             C+  G P P I W  NG    P         +G  E+    A   +H G YTC+A NA 
Sbjct: 3917 TCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEIL---ATQLNHAGRYTCVARNAA 3973

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G       + VHE           PV   +P         S+L V+  + + +  + +G 
Sbjct: 3974 GSAHRHVTLHVHEP----------PVIQPQP---------SELHVILNNPILLPCEATGT 4014

Query: 650  PPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
            P P + W   G  +  S   H      G Q S  ++    ED GTY C A N AG    +
Sbjct: 4015 PSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVR----EDAGTYMCVAQNPAGTALGK 4070

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
              L VQ P     P      +    ++ + + +SC   G P P + W +DG+A+ +    
Sbjct: 4071 IKLNVQVP-----PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQ 4125

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
              VL +    +L +  VQP  AG Y  +  N  G  S    L
Sbjct: 4126 -RVLSSG---SLQIAFVQPGDAGHYTCMAANVAGSSSTSTKL 4163



 Score =  118 bits (296), Expect = 5e-26
 Identities = 102/407 (25%), Positives = 169/407 (41%), Gaps = 54/407 (13%)

Query: 420  PQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKART 479
            P+  ++K N T+   CE   IP   ++W+ +G P++  +    V   A  H L + +A+ 
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD---HVNIAANGHTLQIKEAQI 2737

Query: 480  RDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVI------EGQDFV- 532
             D+G Y+C ASN  G+    + + ++      V PSF  + +   ++      E +D + 
Sbjct: 2738 SDTGRYTCVASNIAGEDELDFDVNIQ------VPPSFQKLWEIGNMLDTGRNGEAKDVII 2791

Query: 533  -----LQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAE 586
                 L C     P P +TW  +G P+  + +     G   L I  A  ED G YTC+A 
Sbjct: 2792 NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAV 2851

Query: 587  NALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK----VMDGSQVTM 642
            N  G+ S    V V           L+P        PI     SDL     V+      +
Sbjct: 2852 NEAGEDSLQYDVRV-----------LVP--------PIIKGANSDLPEEVTVLVNKSALI 2892

Query: 643  TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
                SG+P P   W  +G  + E +   F   G    +   ++   D G Y C A N+AG
Sbjct: 2893 ECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI--TDIGRYVCVAENTAG 2950

Query: 703  EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
              +    L V  P     P    K  ++T  +   + ++C ++G P P + WL++ + + 
Sbjct: 2951 SAKKYFNLNVHVPPSVIGP----KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIK 3006

Query: 763  KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
             +T    V       TL + + +    G+Y  +  N+ GE   + SL
Sbjct: 3007 LNTNTLIVPGGR---TLQIIRAKVSDGGEYTCIAINQAGESKKKFSL 3050



 Score =  115 bits (288), Expect = 4e-25
 Identities = 99/390 (25%), Positives = 160/390 (41%), Gaps = 23/390 (5%)

Query: 417  ESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLK 476
            +  P+   V  N      CE    P   + WF +GTP+   E +  +    G   L +L 
Sbjct: 2579 DGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPL---ESNRNIRILPGGRTLQILN 2635

Query: 477  ARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVL--KDCAVIEGQDFVLQ 534
            A+  ++G YSC A+N  G++   + ++V    ++     +   L  K+  +       L+
Sbjct: 2636 AQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLE 2695

Query: 535  CSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
            C     P   ++W  +GQP++        A    L I++A   D G YTC+A N  G+  
Sbjct: 2696 CEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDE 2755

Query: 594  CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                V +    S +K   L  +     T     +      V+  + +++  + +  PPP 
Sbjct: 2756 LDFDVNIQVPPSFQK---LWEIGNMLDTG----RNGEAKDVIINNPISLYCETNAAPPPT 2808

Query: 654  VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
            + W  +G+ +  S+       G    L I     ED G YTC A N AGE   Q  + V 
Sbjct: 2809 LTWYKDGHPLTSSDKVLILPGG--RVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL 2866

Query: 714  EPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
             P    G        P  VT  + +S LI C  +G P P   W +DG+ L +D  H + L
Sbjct: 2867 VPPIIKGANS---DLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLED-DHHKFL 2922

Query: 772  QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
             N  +  L +   Q    G+Y  + +N  G
Sbjct: 2923 SNGRI--LQILNTQITDIGRYVCVAENTAG 2950



 Score =  114 bits (285), Expect = 9e-25
 Identities = 100/394 (25%), Positives = 163/394 (41%), Gaps = 44/394 (11%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
           PK    P++Q       V   C  +G PKP++AW +    +    GS   Y       L 
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFI---VGS-HRYRMTSDGTLF 667

Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
           +  A  +D+G Y C ASN+ G    + TL+         AP    V  +  V  G   V+
Sbjct: 668 IKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIE------APKLMVVQSELLVALGDITVM 721

Query: 534 QCSVRGTPVPRITWL---LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALG 590
           +C   G P P++ W    L  +P  +       G+  L IQ+    D G YTC+A N  G
Sbjct: 722 ECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL--LKIQETQDLDAGDYTCVAINEAG 779

Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
           + +    + V                    + P+F+Q  +D+ +  GS VT+   V G P
Sbjct: 780 RATGKITLDV-------------------GSPPVFIQEPADVSMEIGSNVTLPCYVQGYP 820

Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQH--SLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
            P + W    N    S  F           +L I  ++  D GTY CEA N  G+++++ 
Sbjct: 821 EPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSET 880

Query: 709 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA-IAGDPFPTVHWLRDGKALCKDTGH 767
            +TV        P     P       GQ + + C  +AG+P P   W+++   L ++   
Sbjct: 881 TVTVT---GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP-- 935

Query: 768 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
           +  ++++   +L +++VQ    G+Y  +  N  G
Sbjct: 936 YITVRSDG--SLHIERVQLQDGGEYTCVASNVAG 967



 Score =  112 bits (280), Expect = 3e-24
 Identities = 89/351 (25%), Positives = 147/351 (41%), Gaps = 39/351 (11%)

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            K  ++ V  +  V+  C+ +G P P + W+ +    R   GS  +        + +  A+
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDN---RLLSGSTSMTFLNRGQIIDIESAQ 1982

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
              D+G Y C A N+ G     ++LQV       VAPS S      AV+      L+C  R
Sbjct: 1983 ISDAGIYKCVAINSAGATELFYSLQVH------VAPSISGSNNMVAVVVNNPVRLECEAR 2036

Query: 539  GTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
            G P P +TWL +G P+    +  +  +G   L +  A   D G YTC+A NA G      
Sbjct: 2037 GIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG------ 2090

Query: 597  WVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 656
                 EK+        +P        P  +    ++ V+    V +  Q    PPP + W
Sbjct: 2091 -----EKQRDIDLRVYVP--------PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTW 2137

Query: 657  LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
            L +G+ + +       +   +  L I++   +DTG YTCEA N AG+      + +  P 
Sbjct: 2138 LKDGHPLLKKPGLSISE--NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP 2195

Query: 717  D--GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
            +  G+      +   +T   G  + + C  +G P P + W + G  +  D+
Sbjct: 2196 NIGGS-----DELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDS 2241



 Score =  107 bits (267), Expect = 1e-22
 Identities = 81/337 (24%), Positives = 134/337 (39%), Gaps = 35/337 (10%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P F   P    + + + ++  C+ +GIP P++ W      +     S+      G   L 
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVN-----GHSELV 4314

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            + +    DSGTY CTA N+ G +     + V+   V +          +     G + +L
Sbjct: 4315 IERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFK-----GDYPSNWIEPLGGNAIL 4369

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             C V+G P P I W   G  I+ +    + G   L I   + ED G YTC+A N  G V 
Sbjct: 4370 NCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVE 4429

Query: 594  CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
             S  +T+             P+   +P   +         +  G ++ +  Q +G P P 
Sbjct: 4430 RSMSLTLQSP----------PIITLEPVETV---------INAGGKIILNCQATGEPQPT 4470

Query: 654  VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
            + W   G+ I   +  +     + +SL I +   EDT  + C A N  G V  +  + VQ
Sbjct: 4471 ITWSRQGHSISWDDRVNVL---SNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527

Query: 714  EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 750
              H G   W  S  R+ + + G+ +     +   P P
Sbjct: 4528 -VHGGFSQW--SAWRACSVTCGKGIQKRSRLCNQPLP 4561



 Score =  104 bits (260), Expect = 7e-22
 Identities = 100/384 (26%), Positives = 159/384 (41%), Gaps = 49/384 (12%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C+ SGIP P+V WF     +R    S  +  D     L + + +  D+G Y+C A N  G
Sbjct: 723  CKTSGIPPPQVKWFKGDLELRP---STFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG 779

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL-LNGQP 553
            + +   TL V    V    P+      D ++  G +  L C V+G P P I W  L+  P
Sbjct: 780  RATGKITLDVGSPPVFIQEPA------DVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMP 833

Query: 554  IQYARSTCEAGVAELH-----IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
            I ++R    + +++L      I +    D GTY C AEN  G++     VTV        
Sbjct: 834  I-FSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV-------- 884

Query: 609  SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV-SGNPPPEVIWLHNGNEIQESE 667
                     +   AP+     S   V++G Q+T+   + +GNP PE  W+ N   + ++ 
Sbjct: 885  ---------TGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNP 935

Query: 668  DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
                   G+ H   I+ V  +D G YTC A N AG       + V        P      
Sbjct: 936  YITVRSDGSLH---IERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-----VLPTIQHGQ 987

Query: 728  RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
            + ++   G  V + C  +G+P P+V W + G+ +   +  F    +  ++      V P 
Sbjct: 988  QILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYV-----VSPG 1042

Query: 788  --HAGQYEILLKNRVGECSCQVSL 809
               +G+Y     N  G    +V L
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQL 1066



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 82/353 (23%), Positives = 138/353 (39%), Gaps = 38/353 (10%)

Query: 459 GSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSS 518
           G  +  +++ S  L + K    D G Y C A ++ G      T + +    +   P    
Sbjct: 471 GVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAG------TGRAQTFFDVSEPPPVIQ 524

Query: 519 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA--ELHIQDALPE 576
           V  +  V  G+  VL C +       +TW  N + ++ A       +A   L ++     
Sbjct: 525 VPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFN 584

Query: 577 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
           D G Y C+  +  G  + S ++TV E              P K T     Q  +      
Sbjct: 585 DAGEYHCMVSSEGGSSAASVFLTVQE--------------PPKVTVMPKNQSFT-----G 625

Query: 637 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
           GS+V++    +G P P++ W  N   I  S  +     GT   L I+   P+D G Y C 
Sbjct: 626 GSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDAGIYGCL 682

Query: 697 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 756
           A NSAG  +  + L   E      P  +     +  +LG   ++ C  +G P P V W +
Sbjct: 683 ASNSAGTDKQNSTLRYIE-----APKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK 737

Query: 757 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
               L   T    ++ +  +  L +++ Q   AG Y  +  N  G  + +++L
Sbjct: 738 GDLELRPST---FLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITL 787



 Score = 74.7 bits (182), Expect = 8e-13
 Identities = 67/274 (24%), Positives = 120/274 (43%), Gaps = 44/274 (16%)

Query: 37   LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
            L P+ + IK   T   E      P   ++W+++GQP+ S     ++    G  +L I   
Sbjct: 2679 LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANG-HTLQIKEA 2735

Query: 97   HEEDRGKYTCEATNGSGARQVT--VELTVEGSFAK--QLGQPVVSKTLGDRFSAPAVETR 152
               D G+YTC A+N +G  ++   V + V  SF K  ++G  + +   G+          
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE---------- 2785

Query: 153  PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
                            + V+    +  + C+    P P +TW K   PL  S +V +   
Sbjct: 2786 ---------------AKDVIINNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILP- 2828

Query: 213  NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVR 272
             G +VL+I     +D G YTC+ VN +G+ S+  ++ +              K  NSD+ 
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV--------LVPPIIKGANSDLP 2879

Query: 273  KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP 306
            +EVT +++K + ++ L + + +   +S Q+ G P
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPR-NSWQKDGQP 2912



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 58/218 (26%), Positives = 86/218 (39%), Gaps = 38/218 (17%)

Query: 58   GYPEPQVTWHRNGQPI-TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
            G P P +TW ++ QP+ T+ G   +    R    L I     ED G+YTC ATN +G  Q
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGR---VLQIAKTLLEDAGRYTCVATNAAGETQ 1908

Query: 117  VTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ 176
              ++L V                       P++E             A K+    V    
Sbjct: 1909 QHIQLHVH--------------------EPPSLED------------AGKMLNETVLVSN 1936

Query: 177  MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
              +  CK  G P P +TW K N  L  S   S++  N  Q+++I      D G+Y C+ +
Sbjct: 1937 PVQLECKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQIIDIESAQISDAGIYKCVAI 1994

Query: 237  NGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
            N +G   +   L +    S + S        N+ VR E
Sbjct: 1995 NSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLE 2032



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 63/242 (26%), Positives = 95/242 (39%), Gaps = 49/242 (20%)

Query: 1102 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1161
            + L  V+V EG  + L+C+ ++ PP  I W  NG+ +  +  + +  +G +  + I+KA 
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAE 3121

Query: 1162 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1221
              D G Y C A N AG+         DD     N   P           P + G E +  
Sbjct: 3122 VSDTGQYVCRAINVAGR---------DDKNFHLNVYVP-----------PSIEGPEREVI 3161

Query: 1222 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
            V+    P                          V L    TG  P T  W+K  K+I+ S
Sbjct: 3162 VETISNP--------------------------VTLTCDATGIPPPTIAWLKNHKRIENS 3195

Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS 1341
            + ++V     GSKL I  ++    G YT +  N  G  Q    L+ +  P   AG    S
Sbjct: 3196 DSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS-IQVPPSVAGAEIPS 3254

Query: 1342 DI 1343
            D+
Sbjct: 3255 DV 3256



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 57/212 (26%), Positives = 84/212 (39%), Gaps = 37/212 (17%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P N+ + E  +        G P P +TW ++G P++      +  G R    L +     
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTM 2449

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
            ED G+YTC   N +G  +    L+V                             P I GE
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVL--------------------------VPPHIVGE 2483

Query: 159  CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
                    L  V VKE Q    +C++TG P P++TW K   PLQ      +   +G + L
Sbjct: 2484 ------NTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII--SGGRFL 2535

Query: 219  EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            +I  V     G YTCL  + +G  S S  L++
Sbjct: 2536 QITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 58/213 (27%), Positives = 88/213 (41%), Gaps = 38/213 (17%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP-ITSGGRFLLDCGIRGTFSLVIHAVH 97
            P  + +  G +   E  V+G P P VTW ++G P I + G  +LD G      L +  +H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG----HILQLKNIH 2354

Query: 98   EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
              D G+Y C A N +G      +L+V                      AP     PSI G
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVH---------------------AP-----PSIIG 2388

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
                        + V E      +C+ +G P P +TW K   P+  S  V +   +G ++
Sbjct: 2389 N-----HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRM 2441

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            L +     +D G YTC+V N +G+      LS+
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV 2474



 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 57/202 (28%), Positives = 81/202 (40%), Gaps = 34/202 (16%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P ++ +  G   +      G P P + W ++G+PI SG    +     G+ +L I+    
Sbjct: 3253 PSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS-TLNIYGALT 3311

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
             D GKYTC ATN +G                            DR     V   P+I G 
Sbjct: 3312 SDTGKYTCVATNPAGEE--------------------------DRIFNLNVYVTPTIRGN 3345

Query: 159  CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
                 A KL  +V          C+ TG P PQ+ WLK  +PL  S+ + +      QV+
Sbjct: 3346 --KDEAEKLMTLV---DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAG--QVI 3398

Query: 219  EIHGVNQDDVGVYTCLVVNGSG 240
             I      DV VYTC+  N +G
Sbjct: 3399 RIVRAQVSDVAVYTCVASNRAG 3420



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 53/200 (26%), Positives = 77/200 (38%), Gaps = 38/200 (19%)

Query: 51   KFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
            + E   RG P P +TW ++G P++S    L    + G   L + +    D G+YTC A N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPVSSFSNGLQV--LSGGRILALTSAQISDTGRYTCVAVN 2087

Query: 111  GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
             +G +Q  ++L V                                    PP    +   V
Sbjct: 2088 AAGEKQRDIDLRVY----------------------------------VPPNIMGEEQNV 2113

Query: 171  VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
             V   Q     C+    P P +TWLK   PL     +S+SE     VL+I      D G 
Sbjct: 2114 SVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENR--SVLKIEDAQVQDTGR 2171

Query: 231  YTCLVVNGSGKASMSAELSI 250
            YTC   N +GK   +  ++I
Sbjct: 2172 YTCEATNVAGKTEKNYNVNI 2191



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 59/251 (23%), Positives = 98/251 (39%), Gaps = 46/251 (18%)

Query: 27  MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
           + + E P   + P+N     G+         GYP+P++ W  N   I    R+ +     
Sbjct: 606 LTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSD-- 663

Query: 87  GTFSLVIHAVHEEDRGKYTCEATNGSGA-RQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
           GT  L I     +D G Y C A+N +G  +Q +    +E                     
Sbjct: 664 GT--LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEA-------------------- 701

Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
                          PK       ++V  G +    CK +G P PQV W KG++ L+PS 
Sbjct: 702 ---------------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746

Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
            + +    G+  L+I      D G YTC+ +N +G+A+    L +     +   F++E  
Sbjct: 747 FLIIDPLLGL--LKIQETQDLDAGDYTCVAINEAGRATGKITLDV----GSPPVFIQEPA 800

Query: 266 ATNSDVRKEVT 276
             + ++   VT
Sbjct: 801 DVSMEIGSNVT 811



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 58/201 (28%), Positives = 86/201 (42%), Gaps = 38/201 (18%)

Query: 51   KFEGRVRGYPEPQVTWHRNGQPITSGGRFL-LDCGIRGTFSLVIHAVHEEDRGKYTCEAT 109
            K E   RG P P +TW+++GQPI S  + L +D   +G + L I      D   YTC   
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYID---KGQY-LHIPRAQVSDSATYTCHVA 1621

Query: 110  NGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGR 169
            N +G        T E SF   +  P                  P I G      AT L +
Sbjct: 1622 NVAG--------TAEKSFHVDVYVP------------------PMIEGN----LATPLNK 1651

Query: 170  VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
             VV    +    CK  G P P +TWLK  VP++ +  + +  + G + LEI    + D G
Sbjct: 1652 QVVIAHSL-TLECKAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRG 1708

Query: 230  VYTCLVVNGSGKASMSAELSI 250
             Y C+  + +G+  +  E+ +
Sbjct: 1709 QYICVATSVAGEKEIKYEVDV 1729



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 56/226 (24%), Positives = 89/226 (39%), Gaps = 41/226 (18%)

Query: 26   SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
            S+ +   P F   P ++ + +G   +   +  G P P++TW  N   I +         +
Sbjct: 4253 SLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFD-----SV 4307

Query: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
             G   LVI  V +ED G Y C A N  G             F K +G   V +       
Sbjct: 4308 NGHSELVIERVSKEDSGTYVCTAENSVG-------------FVKAIGFVYVKEP------ 4348

Query: 146  APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
                   P   G+ P  +   LG   +        +C++ G P P + W +  V ++ S 
Sbjct: 4349 -------PVFKGDYPSNWIEPLGGNAI-------LNCEVKGDPTPTIQWNRKGVDIEISH 4394

Query: 206  RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            R+    + G   L I+G   +D G YTC+  N +G    S  L++Q
Sbjct: 4395 RI---RQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQ 4437



 Score = 64.7 bits (156), Expect = 8e-10
 Identities = 50/213 (23%), Positives = 78/213 (36%), Gaps = 41/213 (19%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P N     G  A     V+G P P + W+R G  I    R        G  SL I+    
Sbjct: 4356 PSNWIEPLGGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQ----LGNGSLAIYGTVN 4411

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
            ED G YTC ATN +G  + ++ LT++                                  
Sbjct: 4412 EDAGDYTCVATNEAGVVERSMSLTLQS--------------------------------- 4438

Query: 159  CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
             PP    +    V+  G     +C+ TG PQP +TW +    +    RV+V   N + + 
Sbjct: 4439 -PPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIA 4497

Query: 219  EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            +     ++D   + C+  N  G   +   + +Q
Sbjct: 4498 D---AQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 56/237 (23%), Positives = 89/237 (37%), Gaps = 40/237 (16%)

Query: 33   PAFILPPR--NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            P  ++ P+  NL +           V G+P P ++W +N QPI      L+   + G  +
Sbjct: 2963 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRT 3019

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L I      D G+YTC A N +G  +    LTV                    +  P+++
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV--------------------YVPPSIK 3059

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
               S            L  V V+EG      C+    P P +TW K    +  S  V + 
Sbjct: 3060 DHDS----------ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL 3109

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRET 264
                 Q+L I      D G Y C  +N +G+   +  L++     ++   R  + ET
Sbjct: 3110 ADG--QMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVET 3164



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 73/322 (22%), Positives = 118/322 (36%), Gaps = 63/322 (19%)

Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133
            +  C   +   T+N+  S      P  +   Q +   EG  + L C+ S +P  ++IW+ 
Sbjct: 957  EYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016

Query: 1134 NGKTLKTTKF-IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV----- 1187
             G+ + T+        +GSL  VS      E+ G Y C A N AG A+   Q+TV     
Sbjct: 1017 KGELISTSSAKFSAGADGSLYVVS---PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPR 1073

Query: 1188 ---------DDAPASENTKAPEMKSR--RPKSSLPPVLGTESDATVKKKPAPKTP--PKA 1234
                      D P   +  A E  +     KS  PP++    +  +    +P+    P  
Sbjct: 1074 VFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG 1133

Query: 1235 AM----------------------------------PPQIIQFPEDQKVRAGESVELFGK 1260
            +M                                  PP+I + P+  KV+ G+ V++   
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCN 1193

Query: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
              GT     TW K    +       V N +    L+I  A     G YT +  N  G+ +
Sbjct: 1194 AQGTPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDE 1251

Query: 1321 AQVNLTVVDKP-----DPPAGT 1337
             ++ L V + P     +PP  T
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNT 1273



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 38/211 (18%)

Query: 42   LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEE 99
            L + EG          G P P + W + G P+   S GR  +  G R    L I    + 
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR---QLQISIAEKS 2262

Query: 100  DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC 159
            D   Y+C A+N +G  +    L V            +  T+ +  S P            
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQV-----------YIRPTITNSGSHPT----------- 2300

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
                      ++V  G+     C++ G P P VTW+K   PL  +  V + ++    +L+
Sbjct: 2301 ---------EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG--HILQ 2349

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            +  ++  D G Y C+ VN +G      +LS+
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 53/208 (25%), Positives = 74/208 (35%), Gaps = 36/208 (17%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
            ++EG +   E      P P +TW++NG+ IT      +   +     L I      D G+
Sbjct: 3071 VREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEI---LADGQMLHIKKAEVSDTGQ 3127

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y C A N +G       L V                             PSI G      
Sbjct: 3128 YVCRAINVAGRDDKNFHLNVY--------------------------VPPSIEGPEREVI 3161

Query: 164  ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
               +   V         +C  TG P P + WLK +  ++ S  + V   +G   L+I   
Sbjct: 3162 VETISNPVT-------LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARS 3214

Query: 224  NQDDVGVYTCLVVNGSGKASMSAELSIQ 251
               D G YTC+  N  GKA     LSIQ
Sbjct: 3215 QHSDSGNYTCIASNMEGKAQKYYFLSIQ 3242



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 48/216 (22%), Positives = 84/216 (38%), Gaps = 44/216 (20%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSG--GRFLLDCGIRGTFSLVIHA- 95
            P  + +        E +V+G P P + W ++G+P+  G     LLD G       V+H  
Sbjct: 1460 PNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG------QVLHLK 1513

Query: 96   -VHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS 154
                 D+G+Y C  +N +G +   ++LT+                    +  P+++    
Sbjct: 1514 NARRNDKGRYQCTVSNAAGKQAKDIKLTI--------------------YIPPSIK---- 1549

Query: 155  IWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNG 214
              G      +  +  ++       +  C+  G P P +TW K   P+  S++    +K  
Sbjct: 1550 -GGNVTTDISVLINSLI-------KLECETRGLPMPAITWYKDGQPIMSSSQALYIDKG- 1600

Query: 215  MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             Q L I      D   YTC V N +G A  S  + +
Sbjct: 1601 -QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 62/258 (24%), Positives = 91/258 (35%), Gaps = 57/258 (22%)

Query: 7    VASSHISKT---------SLSVDPSRVDSMPLTEAPAFILP-PRNLCIKEGATAKFEGRV 56
            + S+H++ T         +   D  R+D       P  I P P N+ +            
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQ--VHVPPSIAPGPTNMTVIVNVQTTLACEA 3827

Query: 57   RGYPEPQVTWHRNGQPIT----SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
             G P+P + W +NG  +          LL  G     SLVI +   +D   Y C  TNG+
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSG-----SLVIISPSVDDTATYECTVTNGA 3882

Query: 113  GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVV 172
            G  + TV+LT                          V+  PSI  E      TK    V+
Sbjct: 3883 GDDKRTVDLT--------------------------VQVPPSIADEPTDFLVTKHAPAVI 3916

Query: 173  KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYT 232
                    +C  +G P P + W K  + L P         +G   +EI     +  G YT
Sbjct: 3917 --------TCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYT 3966

Query: 233  CLVVNGSGKASMSAELSI 250
            C+  N +G A     L +
Sbjct: 3967 CVARNAAGSAHRHVTLHV 3984



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 38/296 (12%)

Query: 515 SFSSVLKDCAVIEGQD----FVLQ-----CSVRGTPVPRITWLLNGQPIQYARSTCEAGV 565
           SFSS++ D   +   +    + LQ     CSV       ++++ NG  +   +   E+  
Sbjct: 422 SFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESAS 481

Query: 566 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 625
             L I      D G Y C+A ++ G      +  V E                    P  
Sbjct: 482 VNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP-------------------PPV 522

Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEV 685
           +Q  +++ V  G +  +T  +       + W  N  +++ +E           SL ++ V
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLELKSV 581

Query: 686 FPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA 745
              D G Y C   +  G       LTVQEP     P     P++ + + G  V I C+  
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFLTVQEP-----PKVTVMPKNQSFTGGSEVSIMCSAT 636

Query: 746 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
           G P P + W  +   +    G        D  TL +K   P  AG Y  L  N  G
Sbjct: 637 GYPKPKIAWTVNDMFI---VGSHRYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 47/193 (24%), Positives = 80/193 (41%), Gaps = 31/193 (16%)

Query: 59   YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
            YP   +TW ++G P+ S     +   + G  +L I    E++ G+Y+C ATN +G     
Sbjct: 2602 YPPATITWFKDGTPLESNRNIRI---LPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658

Query: 119  VELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMG 178
             E+ V                       P +  +  +WG   P  + K   V +K     
Sbjct: 2659 YEVKVY---------------------IPPIINKGDLWG---PGLSPK--EVKIKVNNTL 2692

Query: 179  RFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
               C+    P   ++W K   PL+    V+++  NG   L+I      D G YTC+  N 
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAA-NG-HTLQIKEAQISDTGRYTCVASNI 2750

Query: 239  SGKASMSAELSIQ 251
            +G+  +  +++IQ
Sbjct: 2751 AGEDELDFDVNIQ 2763



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 52/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)

Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176
            L C  +  PP TI W  N K ++ +  + +        + I ++   D G Y C+A N  
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230

Query: 1177 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAM 1236
            G+A+    +++   P+                    V G E                   
Sbjct: 3231 GKAQKYYFLSIQVPPS--------------------VAGAE------------------- 3251

Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
                   P D  V  GE+VEL     G       W+K  K I   E  ++  S NGS L 
Sbjct: 3252 ------IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLN 3305

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            I  A     G YT +  N  G      NL V   P
Sbjct: 3306 IYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 65/241 (26%), Positives = 91/241 (37%), Gaps = 65/241 (26%)

Query: 7    VASSHISKTSLSVD-PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVT 65
            VA S  + T L+V  P R+ S   TE         +  + E + A       G P P + 
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS---TEG--------HYTVNENSQAILPCVADGIPTPAIN 4201

Query: 66   WHRNGQPITSGGRFLLDCGIRGTFS------LVIHAVHEEDRGKYTCEATNGSGARQVTV 119
            W ++          +L   + G ++      L++  V  ED G YTC A N +G    TV
Sbjct: 4202 WKKDN---------VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTV 4252

Query: 120  ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
             LTV                                     P F    G V + +G+  R
Sbjct: 4253 SLTV----------------------------------HVLPTFTELPGDVSLNKGEQLR 4278

Query: 180  FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
             SCK TG P P++TW   N  + P+   SV   NG   L I  V+++D G Y C   N  
Sbjct: 4279 LSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVIERVSKEDSGTYVCTAENSV 4334

Query: 240  G 240
            G
Sbjct: 4335 G 4335



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 41/222 (18%)

Query: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
            V G P P + W ++GQ I     F +    R    LVI      + G Y C A N +G  
Sbjct: 1758 VTGSPPPTIMWLKDGQLIDERDGFKILLNGR---KLVIAQAQVSNTGLYRCMAANTAGDH 1814

Query: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
            +   E+TV                             P+I      K +    RVVVK  
Sbjct: 1815 KKEFEVTVH--------------------------VPPTI------KSSGLSERVVVKYK 1842

Query: 176  QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
             +    C   G P P +TWLK + P+  +A+ ++  ++  +VL+I     +D G YTC+ 
Sbjct: 1843 PVA-LQCIANGIPNPSITWLKDDQPVN-TAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVA 1900

Query: 236  VNGSGKASMSAELSIQ---GLDSANRSFVRETKATNSDVRKE 274
             N +G+     +L +     L+ A +  + ET   ++ V+ E
Sbjct: 1901 TNAAGETQQHIQLHVHEPPSLEDAGK-MLNETVLVSNPVQLE 1941



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 49/218 (22%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P N  +    +   E +  G P P +TW ++G P+ +     ++ G +    L I +  E
Sbjct: 1648 PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK---KLEIMSAQE 1704

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
             DRG+Y C AT+ +G +++  E+                    D    PA+E        
Sbjct: 1705 IDRGQYICVATSVAGEKEIKYEV--------------------DVLVPPAIEG------- 1737

Query: 159  CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV- 217
                   +    +V    +    C +TG P P + WLK            + E++G ++ 
Sbjct: 1738 -----GDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG--------QLIDERDGFKIL 1784

Query: 218  -----LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                 L I      + G+Y C+  N +G      E+++
Sbjct: 1785 LNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 56/260 (21%), Positives = 88/260 (33%), Gaps = 53/260 (20%)

Query: 58   GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
            G P P + W +N + I +     +   + G   L I      D G YTC A+N  G  Q 
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRI-LSGGSKLQIARSQHSDSGNYTCIASNMEGKAQ- 3234

Query: 118  TVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG-ECPPKFATKLGRVVVKEGQ 176
                                     ++   +++  PS+ G E P   +  LG  V     
Sbjct: 3235 -------------------------KYYFLSIQVPPSVAGAEIPSDVSVLLGENV----- 3264

Query: 177  MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
                 C   G P P + WLK   P+       +        L I+G    D G YTC+  
Sbjct: 3265 --ELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVAT 3322

Query: 237  NGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
            N +G+      L++         +V  T   N D  +++  ++       S+    ++  
Sbjct: 3323 NPAGEEDRIFNLNV---------YVTPTIRGNKDEAEKLMTLVD-----TSINIECRATG 3368

Query: 297  CSSPQRGGSPPWAANSQPQP 316
               PQ      W  N  P P
Sbjct: 3369 TPPPQIN----WLKNGLPLP 3384



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 56/244 (22%), Positives = 94/244 (38%), Gaps = 48/244 (19%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG--RFLLDCGIRGTFSLVIHAV 96
            P  + +    +A  E    G P P+ +W ++GQP+      +FL +  I     L I   
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI-----LQILNT 2933

Query: 97   HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
               D G+Y C A N +G+ +    L V                             PS+ 
Sbjct: 2934 QITDIGRYVCVAENTAGSAKKYFNLNVH--------------------------VPPSVI 2967

Query: 157  GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
            G        K   + V        +C+++G P P ++WLK   P++ +    +    G +
Sbjct: 2968 GP-------KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGR 3018

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL------SIQGLDSANRSFVRETKATNSD 270
             L+I      D G YTC+ +N +G++     L      SI+  DS + S V   + T+  
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVS 3078

Query: 271  VRKE 274
            +  E
Sbjct: 3079 LECE 3082



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 38/200 (19%)

Query: 51   KFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
            + E +  G P P +TW+++ + + SG   +     RG   + I +    D G Y C A N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNR-LLSGSTSMTFLN-RGQI-IDIESAQISDAGIYKCVAIN 1995

Query: 111  GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
             +GA ++                          F +  V   PSI G      +  +  V
Sbjct: 1996 SAGATEL--------------------------FYSLQVHVAPSISG------SNNMVAV 2023

Query: 171  VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
            VV      R  C+  G P P +TWLK   P+  S    +   +G ++L +      D G 
Sbjct: 2024 VVNNPV--RLECEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGR 2080

Query: 231  YTCLVVNGSGKASMSAELSI 250
            YTC+ VN +G+     +L +
Sbjct: 2081 YTCVAVNAAGEKQRDIDLRV 2100



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 52/226 (23%), Positives = 85/226 (37%), Gaps = 48/226 (21%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            ++ V  GK + L+C+V   PP T+ W  +G  L   K + +  EG +  + ++     D 
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSDT 2358

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            G Y CVA N AG  +    ++V  AP                   P ++G          
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSV-HAP-------------------PSIIGNH-------- 2390

Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                            + PE+  V    SV L  + +G    + TW K    +  S  ++
Sbjct: 2391 ----------------RSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVR 2434

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +     G  L ++    E  G YT +V N  G  +    L+V+  P
Sbjct: 2435 I--LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 60/275 (21%), Positives = 100/275 (36%), Gaps = 49/275 (17%)

Query: 1103 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1162
            K+ +  V     + L+C+ + +P   I W  + + L  +  +     G +  + IE A  
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQI 1983

Query: 1163 EDRGLYKCVAKNDAGQAECSCQVTVDDAPA---------------------SENTKAPE- 1200
             D G+YKCVA N AG  E    + V  AP+                     +    AP  
Sbjct: 1984 SDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSL 2043

Query: 1201 --MKSRRPKSSLPPVLGTESDATVKKKPAPKTPP---------------------KAAMP 1237
              +K   P SS    L   S   +    + +                        +  +P
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103

Query: 1238 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
            P I+   ++  V   ++VEL  +     P T TW+K    + +   + +  SEN S L I
Sbjct: 2104 PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI--SENRSVLKI 2161

Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
              A+ +  G YT    N  G  +   N+ +   P+
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPN 2196



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 52/212 (24%), Positives = 82/212 (38%), Gaps = 49/212 (23%)

Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176
            L C+ ++ PP T+ W  +G  L ++  +++   G +  + I +A  ED G Y CVA N+A
Sbjct: 2797 LYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEA 2854

Query: 1177 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL-GTESDATVKKKPAPKTPPKAA 1235
            G+      V V                      +PP++ G  SD                
Sbjct: 2855 GEDSLQYDVRV---------------------LVPPIIKGANSD---------------- 2877

Query: 1236 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1295
                    PE+  V   +S  +    +G+     +W K  + + E +H K     NG  L
Sbjct: 2878 -------LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRIL 2928

Query: 1296 TILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             IL  +    G Y  + EN  GS +   NL V
Sbjct: 2929 QILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960



 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 53/213 (24%), Positives = 79/213 (37%), Gaps = 49/213 (23%)

Query: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
            L L+C+ + +P   + W  +G  +K    I +   G    + I  A   DRG Y CVA +
Sbjct: 1659 LTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATS 1716

Query: 1175 DAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKA 1234
             AG+ E   +V V   PA E                    G E+   +            
Sbjct: 1717 VAGEKEIKYEVDVLVPPAIEG-------------------GDETSYFI------------ 1745

Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294
                          V     +EL   VTG+ P T  W+K  + I E +  K+    NG K
Sbjct: 1746 --------------VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKI--LLNGRK 1789

Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            L I  A+  + G Y  +  N  G  + +  +TV
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 48/196 (24%), Positives = 77/196 (39%), Gaps = 38/196 (19%)

Query: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
            V G P P + W+++   +T          +     L +     ED G+Y+C+A N +G  
Sbjct: 1384 VEGTPSPIIMWYKDNVQVTESSTIQT---VNNGKILKLFRATPEDAGRYSCKAINIAGTS 1440

Query: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
            Q    + V       L  P +   +G  F               P + +  L R V  E 
Sbjct: 1441 QKYFNIDV-------LVPPTI---IGTNF---------------PNEVSVVLNRDVALE- 1474

Query: 176  QMGRFSCKITGRPQPQVTWLKGNVPL-QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
                  C++ G P P + W K   PL      V + ++   QVL +    ++D G Y C 
Sbjct: 1475 ------CQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRG--QVLHLKNARRNDKGRYQCT 1526

Query: 235  VVNGSGKASMSAELSI 250
            V N +GK +   +L+I
Sbjct: 1527 VSNAAGKQAKDIKLTI 1542



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 51/227 (22%), Positives = 88/227 (38%), Gaps = 39/227 (17%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            ++V +     L L+C+  + P A++ W  +G+ LK+   + ++  G   ++ I++A   D
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISD 2739

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
             G Y CVA N AG+ E    V +   P+ +               +  +L T  +     
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPSFQKL-----------WEIGNMLDTGRNG---- 2784

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
                                E + V     + L+ +     P T TW K    +  S+  
Sbjct: 2785 --------------------EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSD-- 2822

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            KV     G  L I  A+ E  G YT +  N+ G    Q ++ V+  P
Sbjct: 2823 KVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 81/391 (20%), Positives = 145/391 (37%), Gaps = 68/391 (17%)

Query: 1029 AKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNE 1088
            AK  + + P     P  T  P G+ K  E   S S   L         C   +      +
Sbjct: 1114 AKETQLISPFS---PRHTFLPSGSMKITETRTSDSGMYL---------CVATNIAGNVTQ 1161

Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILS 1147
                +    P  ++  + + V  G+++ + C     P   I W+  G T+    +  + +
Sbjct: 1162 AVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221

Query: 1148 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1207
             +G+L   SI++A P D G+Y CVA N AG  E    + V + P  E+ + P        
Sbjct: 1222 PDGTL---SIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP-------- 1270

Query: 1208 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1267
                       + T +++ A           Q I+FP   K              GT   
Sbjct: 1271 ----------YNTTFQERVA----------NQRIEFPCPAK--------------GTPKP 1296

Query: 1268 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            T  W+   +++   E   +   E+G+ L I +      G Y  +  N+ G+ + + NL  
Sbjct: 1297 TIKWLHNGRELTGRE-PGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNL-- 1353

Query: 1328 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1387
              K   P        + + S+ L+   + +       S  I +W   N    E +T ++ 
Sbjct: 1354 --KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPS-PIIMWYKDNVQVTESSTIQTV 1410

Query: 1388 S----FNVQDLLPDHEYKFRVRAINVYGTSE 1414
            +      +    P+   ++  +AIN+ GTS+
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 41/201 (20%)

Query: 42   LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV--HEE 99
            + + +G++        G P P + W R+GQP+       +      T  +V+  +    E
Sbjct: 3445 ITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVS-----THGMVLQLLKAETE 3499

Query: 100  DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC 159
            D GKYTC A+N +G         V   F  ++ +P                  P I G  
Sbjct: 3500 DSGKYTCIASNEAG--------EVSKHFILKVLEP------------------PHING-- 3531

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
                + +   + V        +C  +G P P++TW+K   PL  + +V      G +VL 
Sbjct: 3532 ----SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQT--LGGGEVLR 3585

Query: 220  IHGVNQDDVGVYTCLVVNGSG 240
            I     +D G YTCL  + +G
Sbjct: 3586 ISTAQVEDTGRYTCLASSPAG 3606



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 58/250 (23%), Positives = 95/250 (38%), Gaps = 52/250 (20%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSLCSVSIEKALPE 1163
            DV V  G+ + L C  +  P   I W  +GK + +  T+ I +S  GS  +++I  AL  
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTS 3312

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y CVA N AG+ +    + V                       P + G + +A   
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNV--------------------YVTPTIRGNKDEA--- 3349

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                                 E        S+ +  + TGT P    W+K    +  S H
Sbjct: 3350 ---------------------EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSH 3388

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPAGTPCAS 1341
            +++  +  G  + I+ A+      YT +  N+ G      NL V   P  D   GT   +
Sbjct: 3389 IRLLAA--GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446

Query: 1342 DIRSSSLTLS 1351
             ++ SS +++
Sbjct: 3447 VLKGSSTSMA 3456



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 50/227 (22%), Positives = 89/227 (39%), Gaps = 43/227 (18%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            +DV V       L C+  S PPATI W  +G  L++ + I +   G   ++ I  A  ++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILNAQEDN 2640

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
             G Y CVA N+AG+                      +K    K  +PP++  + D     
Sbjct: 2641 AGRYSCVATNEAGEM---------------------IKHYEVKVYIPPII-NKGDLW--- 2675

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
               P   PK            + K++   ++ L  +       + +W K  + ++  +H+
Sbjct: 2676 --GPGLSPK------------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHV 2721

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +  + NG  L I  A+    G YT +  N  G  +   ++ +   P
Sbjct: 2722 NI--AANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 55/232 (23%), Positives = 79/232 (34%), Gaps = 56/232 (24%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCSV 1155
            P  + +  ++HV     +LL C+ +  P   I W   G  + T+     +L   G    +
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG----L 4043

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1215
             I +A+ ED G Y CVA+N AG A    ++ V   P      +P +K        P  L 
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI----SPHLKEYVIAVDKPITLS 4099

Query: 1216 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1275
             E+D                                           G  P   TW K  
Sbjct: 4100 CEAD-------------------------------------------GLPPPDITWHKDG 4116

Query: 1276 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            + I ES   +V +S     L I   +    G YT +  N  GS      LTV
Sbjct: 4117 RAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 62/279 (22%), Positives = 99/279 (35%), Gaps = 54/279 (19%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P     L++  +A  K + L C+    PP  I W  +G+ +  +    +   GSL    +
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFV 4138

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP------ 1211
            +   P D G Y C+A N AG +  S ++TV   P   +T+     +   ++ LP      
Sbjct: 4139 Q---PGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI 4195

Query: 1212 --PVLGTESD--------------------------------ATVKKKPAPKTPPKAAMP 1237
              P +  + D                                  V    A +     ++ 
Sbjct: 4196 PTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT 4255

Query: 1238 ----PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG- 1292
                P   + P D  +  GE + L  K TG      TW  F   I  +      +S NG 
Sbjct: 4256 VHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW-TFNNNIIPAHF----DSVNGH 4310

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            S+L I    +E  G Y    EN +G  +A +    V +P
Sbjct: 4311 SELVIERVSKEDSGTYVCTAENSVGFVKA-IGFVYVKEP 4348



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 63/278 (22%), Positives = 97/278 (34%), Gaps = 53/278 (19%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
            C   ++  TD +  +     AP       ++ VA G   +++C+ S  PP  + W     
Sbjct: 681  CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740

Query: 1137 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1196
             L+ + F+I+  +  L  + I++    D G Y CVA N+AG+A  + ++T+D        
Sbjct: 741  ELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGRA--TGKITLD-------- 788

Query: 1197 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256
                                                    PP  IQ P D  +  G +V 
Sbjct: 789  -------------------------------------VGSPPVFIQEPADVSMEIGSNVT 811

Query: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE--NGSKLTILAARQEHCGCYTLLVEN 1314
            L   V G    T  W +       S    V +        L IL       G Y    EN
Sbjct: 812  LPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAEN 871

Query: 1315 KLGSRQAQVNLTVVDKPDPPAG--TPCASDIRSSSLTL 1350
            + G  Q++  +TV     P  G     A+ I    LTL
Sbjct: 872  QFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTL 909



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 9/135 (6%)

Query: 679 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 738
           +L I +V   D G Y C A +SAG  R Q    V EP     P  I  P +VT + G+  
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP-----PPVIQVPNNVTVTPGERA 537

Query: 739 LISCAIAGDPFPTVHWLR-DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 797
           +++C I       + W R D      +      L N    +L LK V+   AG+Y  ++ 
Sbjct: 538 VLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVS 594

Query: 798 NRVGECSCQVSLMLQ 812
           +  G  +  V L +Q
Sbjct: 595 SEGGSSAASVFLTVQ 609



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 51/218 (23%), Positives = 78/218 (35%), Gaps = 51/218 (23%)

Query: 1115 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1174
            L L C V+  PP TI+W  +G+ +       +   G    + I +A   + GLY+C+A N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGR--KLVIAQAQVSNTGLYRCMAAN 1809

Query: 1175 DAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKA 1234
             AG  +   +VTV   P  +++                  G      VK KP        
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSS------------------GLSERVVVKYKPVALQCIAN 1851

Query: 1235 AMP-PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
             +P P I    +DQ V   +                             ++K+++S  G 
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQG----------------------------NLKIQSS--GR 1881

Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             L I     E  G YT +  N  G  Q  + L V + P
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 3/107 (2%)

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            P +K + S+++  + V EG++   +C+    P P + W+K+ + I ES H +I  D    
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ-- 3113

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
              L I      D  +Y C+A+N  G       L V      EG   E
Sbjct: 3114 -MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPERE 3159



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 53/216 (24%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G   +L C+V  DP  TI W   G  ++ +  I     GSL   +I   + ED G Y CV
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYTCV 4420

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A N+AG  E S  +T+                       PP++  E              
Sbjct: 4421 ATNEAGVVERSMSLTLQS---------------------PPIITLE-------------- 4445

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                        P +  + AG  + L  + TG    T TW +    I   + + V ++  
Sbjct: 4446 ------------PVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN-- 4491

Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             + L I  A++E    +  +  N +GS   +V + V
Sbjct: 4492 -NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 46/215 (21%), Positives = 77/215 (35%), Gaps = 51/215 (23%)

Query: 1117 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1176
            + C V S  P T+ +  NG TL   +++   +E +  ++ I K    D G Y+C+A + A
Sbjct: 449  IPCSVDSLLPFTLSFVRNGVTLGVDQYL---KESASVNLDIAKVTLSDEGFYECIAVSSA 505

Query: 1177 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAM 1236
            G         V +                                               
Sbjct: 506  GTGRAQTFFDVSE----------------------------------------------- 518

Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
            PP +IQ P +  V  GE   L   +        TW +  + ++ +E  ++    N S L 
Sbjct: 519  PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LE 577

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            + + +    G Y  +V ++ GS  A V LTV + P
Sbjct: 578  LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 51/229 (22%), Positives = 82/229 (35%), Gaps = 53/229 (23%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            +++ V E   + L C+ S  P  +I W  +G  +  +  + +   G +  + + +   ED
Sbjct: 2394 ENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMED 2451

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
             G Y CV +N AG+      ++V                                     
Sbjct: 2452 AGQYTCVVRNAAGEERKIFGLSV------------------------------------- 2474

Query: 1225 KPAPKTPPKAAMPPQII--QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
                       +PP I+     ED KV+  +SV L  +VTG      TW K  + +QE E
Sbjct: 2475 ----------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524

Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
               +     G  L I   +  H G YT L  +  G +    +L V   P
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSP 2571



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 5/84 (5%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            HV P F++   D+ + +G   R  CK  G P P++ W  ++  I    HF      +G+ 
Sbjct: 4257 HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII--PAHFD---SVNGHS 4311

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
             L+I  V  +D   Y C A NS+G
Sbjct: 4312 ELVIERVSKEDSGTYVCTAENSVG 4335



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 46/214 (21%), Positives = 78/214 (36%), Gaps = 46/214 (21%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L+DV V E + + L C+V+ +P   I W  +G+ L+  +   +   G    + I      
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVP 2543

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
              G Y C+A + AG    S  + V  +P                     + G  SD    
Sbjct: 2544 HTGRYTCLASSPAGHKSRSFSLNVFVSPT--------------------IAGVGSDGN-- 2581

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                                PED  V       L  +     P T TW K    ++ + +
Sbjct: 2582 --------------------PEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317
            +++     G  L IL A++++ G Y+ +  N+ G
Sbjct: 2622 IRI--LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 53/249 (21%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            +++ V +G    + C     P  ++ W  +G+ L     + +S  G +  + + KA  ED
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMV--LQLLKAETED 3500

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
             G Y C+A N+AG                E +K   +K   P    P + G+E       
Sbjct: 3501 SGKYTCIASNEAG----------------EVSKHFILKVLEP----PHINGSEEH----- 3535

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
                                E+  V     +EL    +G      TWMK  + + +++  
Sbjct: 3536 --------------------EEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD-- 3573

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI- 1343
            +V+    G  L I  A+ E  G YT L  +  G    +  L  V  P   AGT    DI 
Sbjct: 3574 QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY-LVRVHVPPNIAGTDEPRDIT 3632

Query: 1344 --RSSSLTL 1350
              R+  +TL
Sbjct: 3633 VLRNRQVTL 3641



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 3/94 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            HV P      + L  +EG      CK  G P P V+W K  + I  S      +    + 
Sbjct: 978  HVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS---SAKFSAGADG 1034

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            SL +    G++  +Y C A N+ G A    +L V
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 3/97 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            HV P    T     V E S A   C  +G P P + W KD+  +    +    Y  +   
Sbjct: 4166 HVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL---ANLLGKYTAEPYG 4222

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
             LI+ +V  +D   YTC A N+ GE T T  L V  +
Sbjct: 4223 ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVL 4259



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 61/259 (23%), Positives = 88/259 (33%), Gaps = 55/259 (21%)

Query: 1082 AGTTDNEKRSESQGTAPAFKQKLQ--DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1139
            AGTT+  K +      P  K K Q  +V V   +   L C+V   P   I+W  +   + 
Sbjct: 1344 AGTTER-KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVT 1402

Query: 1140 TTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1199
             +  I     G +  + + +A PED G Y C A N AG ++    + V            
Sbjct: 1403 ESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV------------ 1448

Query: 1200 EMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQII--QFPEDQKVRAGESVEL 1257
                                                +PP II   FP +  V     V L
Sbjct: 1449 -----------------------------------LVPPTIIGTNFPNEVSVVLNRDVAL 1473

Query: 1258 FGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1317
              +V GT      W K  K +   +   VE  + G  L +  AR+   G Y   V N  G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532

Query: 1318 SRQAQVNLTVVDKPDPPAG 1336
             +   + LT+   P    G
Sbjct: 1533 KQAKDIKLTIYIPPSIKGG 1551



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGN 1813
            HV P  S +   + VV  +  R +C+  G P P + W KD   +   S   Q+     G 
Sbjct: 2009 HVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQV---LSGG 2065

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGE 1839
              L ++     D  +YTC AVN+ GE
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGE 2091



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 12/142 (8%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            GD   VA++       S+      S+ L   P   L P    I  G       +  G P+
Sbjct: 4415 GDYTCVATNEAGVVERSM------SLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQ 4468

Query: 62   PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTV 119
            P +TW R G  I+   R      +    SL I    +ED  ++ C A N  GS   +V V
Sbjct: 4469 PTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524

Query: 120  ELTVEGSFAKQLGQPVVSKTLG 141
             + V G F++       S T G
Sbjct: 4525 IVQVHGGFSQWSAWRACSVTCG 4546



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 5/118 (4%)

Query: 1082 AGTTDNEKRSESQGTA---PAFKQK-LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1137
            A  T  + + E + T    P  K   L +  V + K + LQC  +  P  +I W  + + 
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866

Query: 1138 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
            + T +  +  Q      + I K L ED G Y CVA N AG+ +   Q+ V + P+ E+
Sbjct: 1867 VNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLED 1923



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            ++ V++GS+    C  +G P P + W +D Q +    H  +         L +     +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV---STHGMVLQLLKAETED 3500

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
              KYTC A N  GE   +   I++ +E     G EE E
Sbjct: 3501 SGKYTCIASNEAGEV--SKHFILKVLEPPHINGSEEHE 3536



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 10/155 (6%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            WQK G  V   GR  ++    GL   ++      + +   +  +   + +  L       
Sbjct: 4021 WQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV----- 4075

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
              V P  S  +++  +         C+ +G P P++ W KD ++I ES   ++      +
Sbjct: 4076 -QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV----LSS 4130

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             SL I+ V   D   YTC A N  G ++ + +L V
Sbjct: 4131 GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            +L V  G     +CK  G P P+V WFK D  +R S    ID        L I +    D
Sbjct: 710  ELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQETQDLD 766

Query: 1826 DAKYTCKAVNSLGEAT 1841
               YTC A+N  G AT
Sbjct: 767  AGDYTCVAINEAGRAT 782



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 5/88 (5%)

Query: 1753 KPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            K HV P     + + ++ V+        C++EG P P ++W+KD+  + ES   Q     
Sbjct: 1354 KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ---TV 1410

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            +    L +     +D  +Y+CKA+N  G
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAG 1438



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 5/107 (4%)

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            PH+      T+ D++V E  +    C++ G P PE+ W KD Q ++E     I     G 
Sbjct: 2478 PHIVG--ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHI---ISGG 2532

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
              L I++V      +YTC A +  G  + +  L V       G G +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSD 2579



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 3/106 (2%)

Query: 1755 HVKPYF-SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            HV P   S  + +  VV+       C   G P+P + W KDDQ +  ++   +     G 
Sbjct: 1823 HVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGR 1881

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
              L I+    +D  +YTC A N+ GE     +L V      E  G+
Sbjct: 1882 V-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGK 1926



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 1/98 (1%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            D+ V+ G      C   G P P + W KD + I      +I    +G+ +L I      D
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSD 3313

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
              KYTC A N  GE      L V       G  +E E+
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 45/226 (19%), Positives = 82/226 (36%), Gaps = 48/226 (21%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            D+ V     + L+C+    P   I W  +G+ + ++   +   +G    + I +A   D 
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDS 1613

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
              Y C   N AG AE S  V V   P  E   A                           
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLAT-------------------------- 1647

Query: 1226 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                              P +++V    S+ L  K  G      TW+K    ++ +++++
Sbjct: 1648 ------------------PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR 1689

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +E    G KL I++A++   G Y  +  +  G ++ +  + V+  P
Sbjct: 1690 IE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP 1733



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            +D+ V   +++ L+C+  + PP  I W  NG+ L+ T  + +   G    + I  A   D
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGD 3686

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAP 1191
               Y CVA N AG+      +TV+  P
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPP 3713



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            D+ V+  S  + +C+  G P P + W+KD Q I  S   Q  Y + G   L I      D
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSD 1612

Query: 1826 DAKYTCKAVNSLG--EATCTAELIVETMEEG 1854
             A YTC   N  G  E +   ++ V  M EG
Sbjct: 1613 SATYTCHVANVAGTAEKSFHVDVYVPPMIEG 1643



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 4/87 (4%)

Query: 1755 HVKP-YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            HV P        +L VV  +     C++ G+P P++ W K++Q I+ + +  I     G 
Sbjct: 2961 HVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGG 3017

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEA 1840
             +L I      D  +YTC A+N  GE+
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGES 3044



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 20/153 (13%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-EDVSQAFLEAVAEE 1752
            W+K G+ V       SM  +  LSG     G       AEK ++       + +   A++
Sbjct: 2230 WKKKGSPVLT----DSMGRVRILSG-----GRQLQISIAEKSDAALYSCVASNVAGTAKK 2280

Query: 1753 KPHVKPYFSKTIR-------DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1805
            + +++ Y   TI        ++ V  G +   +C+++G P P V W KD   + +++  +
Sbjct: 2281 EYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340

Query: 1806 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            I    D    L + ++   D  +Y C AVN  G
Sbjct: 2341 I---LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-DYDEDGNCSL 1816
            P F +   D+ +  GS     C ++GYP+P + W + D     SR F +    +    +L
Sbjct: 793  PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852

Query: 1817 IISDVCGDDDAKYTCKAVNSLGE 1839
             I ++   D   Y C+A N  G+
Sbjct: 853  FILNLWASDKGTYICEAENQFGK 875



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            D+ V+  S     C+   YP   + WFKD   +  +R+ +I     G  +L I +   D+
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI---LPGGRTLQILNAQEDN 2640

Query: 1826 DAKYTCKAVNSLGE 1839
              +Y+C A N  GE
Sbjct: 2641 AGRYSCVATNEAGE 2654



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            ++ VVE ++    C+  G P P + WFKD   +  S   +I     G   L +     +D
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMED 2451

Query: 1826 DAKYTCKAVNSLGE 1839
              +YTC   N+ GE
Sbjct: 2452 AGQYTCVVRNAAGE 2465



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 5/89 (5%)

Query: 1755 HVKPYFSKTI--RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
            HV P  + T   RD+ V+       +CK +  P P + W ++ + ++ +   +I     G
Sbjct: 3617 HVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRI---LSG 3673

Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEAT 1841
               L I++    D A YTC A N  G+ T
Sbjct: 3674 GRYLQINNADLGDTANYTCVASNIAGKTT 3702



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 1/95 (1%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            HV P  +    ++ V+        C+  G P P + W K+   +   ++ Q  Y    + 
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQN-QNSYRLLSSG 3859

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            SL+I     DD A Y C   N  G+   T +L V+
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)

Query: 1108 HVAEGKKLLLQCQV-SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            +V EG++L L C + + +P     W  N   L    +I +  +GSL    IE+   +D G
Sbjct: 900  NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSL---HIERVQLQDGG 956

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
             Y CVA N AG    +  V V   P  ++
Sbjct: 957  EYTCVASNVAGTNNKTTSVVVHVLPTIQH 985



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 16/150 (10%)

Query: 1694 WQKTGNAVRAIGR----LSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1749
            W K G+ V +       LS   +++  S + S TG  T        E + D+        
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-------- 2096

Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1809
             + + +V P      +++ V+   A    C+ +  P P + W KD   + +     I   
Sbjct: 2097 -DLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI--- 2152

Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +    L I D    D  +YTC+A N  G+
Sbjct: 2153 SENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182



 Score = 39.7 bits (91), Expect = 0.028
 Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 3/93 (3%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+  +    DC + G P P ++W KD Q I E   F+I  +      L+I+     +   
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGL 1802

Query: 1829 YTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1861
            Y C A N+ G+     E+ V      +  G  E
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSE 1835



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 50/227 (22%), Positives = 81/227 (35%), Gaps = 50/227 (22%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            ++V V   K  L++C  S  P     W  +G+ L           G +  + I      D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI--LQILNTQITD 2937

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1224
             G Y CVA+N AG A+    +         N   P           P V+G +S      
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNL---------NVHVP-----------PSVIGPKS------ 2971

Query: 1225 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1284
                                E+  V     + L  +V+G  P   +W+K  + I+ + + 
Sbjct: 2972 --------------------ENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNT 3011

Query: 1285 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             +     G  L I+ A+    G YT +  N+ G  + + +LTV   P
Sbjct: 3012 LI--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 6/100 (6%)

Query: 1740 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1799
            +VS+ F+  V E  PH+    S+   ++ V+  +     C   G P P++ W KD + + 
Sbjct: 3514 EVSKHFILKVLEP-PHING--SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP 3570

Query: 1800 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
            ++   Q      G   L IS    +D  +YTC A +  G+
Sbjct: 3571 QTDQVQ---TLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 10/123 (8%)

Query: 1744 AFLEAVAEEKPHVKPYFSKTIR-------DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1796
            A +   AE+  HV  Y    I        + +VV   +   +CK  G P P + W KD  
Sbjct: 1621 ANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGV 1680

Query: 1797 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1856
             ++ + + +I   E G   L I      D  +Y C A +  GE     E+ V      EG
Sbjct: 1681 PVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEG 1737

Query: 1857 EGE 1859
              E
Sbjct: 1738 GDE 1740



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 85/475 (17%), Positives = 153/475 (32%), Gaps = 91/475 (19%)

Query: 877  VETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVK-- 934
            V+T      ++R   +  +DFR    +K +                +DF+  + R V+  
Sbjct: 299  VKTSSSGRHSVRITGLSTIDFRAGFSRKPT----------------LDFKKTVSRPVQGI 342

Query: 935  PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPA-----TPDFRSVLGGKK 989
            P  V      + +P ++D   +L+  G+S   +P K  P +         DF  V   + 
Sbjct: 343  PTYVLLNTSGISTPARIDLLELLSISGSSLKTIPVKYYPHRKPYGIWNISDF--VPPNEA 400

Query: 990  KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 1049
                  G    + L  +   SS   S+  P  P   +    P   L+P       ++L P
Sbjct: 401  FFLKVTGYDKDDYLFQRV--SSVSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLP 458

Query: 1050 MG--------NAKPDENLKSASKEELK--KDVKND---VNCKRGHAGTTDNEKRSESQGT 1096
                          D+ LK ++   L   K   +D     C    +  T   +       
Sbjct: 459  FTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
             P   Q   +V V  G++ +L C + S     + W  N + ++  +   +    +L S+ 
Sbjct: 519  PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLE 577

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            ++     D G Y C+  ++ G +  S  +TV +                           
Sbjct: 578  LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQE--------------------------- 610

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                                PP++   P++Q    G  V +    TG       W     
Sbjct: 611  --------------------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDM 650

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             I  S   ++ +      L I  A  +  G Y  L  N  G+ +    L  ++ P
Sbjct: 651  FIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            ++P ++ T +  E V      F C  +G P P + W  + + +   R   I   EDG   
Sbjct: 1267 LEPPYNTTFQ--ERVANQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTL- 1322

Query: 1816 LIISDVCGDDDAKYTCKAVNSLG 1838
            L+I+ V   D+ +Y C AVN  G
Sbjct: 1323 LVIASVTPYDNGEYICVAVNEAG 1345



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            G  A  +C+++G P P + W +    I  S   +    + GN SL I     +D   YTC
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTC 4419

Query: 1832 KAVNSLGEATCTAELIVET 1850
             A N  G    +  L +++
Sbjct: 4420 VATNEAGVVERSMSLTLQS 4438



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 8/104 (7%)

Query: 1735 LESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD 1794
            + SE   S A +    +E P V    +   ++     GS     C   GYP P++ W  +
Sbjct: 593  VSSEGGSSAASVFLTVQEPPKV----TVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN 648

Query: 1795 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            D  I  S  +++  D     +L I +    D   Y C A NS G
Sbjct: 649  DMFIVGSHRYRMTSDG----TLFIKNAAPKDAGIYGCLASNSAG 688



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 57/271 (21%), Positives = 90/271 (33%), Gaps = 60/271 (22%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
            C   +A  TD  +        P+      ++ V    +  L C+ +  P  +I W  NG 
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGH 3842

Query: 1137 TLKT----TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
             L        + +LS  GSL  +S      +D   Y+C   N AG  + +  +TV     
Sbjct: 3843 LLNVDQNQNSYRLLS-SGSLVIIS---PSVDDTATYECTVTNGAGDDKRTVDLTV----- 3893

Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
                             +PP +  E    +  K AP      A     + FP     + G
Sbjct: 3894 ----------------QVPPSIADEPTDFLVTKHAPAVITCTASG---VPFPSIHWTKNG 3934

Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
              + L  +  G + +                       +   + ILA +  H G YT + 
Sbjct: 3935 --IRLLPRGDGYRIL-----------------------SSGAIEILATQLNHAGRYTCVA 3969

Query: 1313 ENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1343
             N  GS    V L V    +PP   P  S++
Sbjct: 3970 RNAAGSAHRHVTLHV---HEPPVIQPQPSEL 3997



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 11/97 (11%)

Query: 1751 EEKPHVKPYFSK--------TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1802
            E K ++ P  +K        + +++++   +    +C+    P   + W+KD Q ++   
Sbjct: 2660 EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD 2719

Query: 1803 HFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
            H  I        +L I +    D  +YTC A N  GE
Sbjct: 2720 HVNI---AANGHTLQIKEAQISDTGRYTCVASNIAGE 2753



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 6/89 (6%)

Query: 1763 TIRDLEVVEGSAARF--DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
            T+  +E V  +  +   +C+  G P P + W +   SI       +      N SL I+D
Sbjct: 4443 TLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL----SNNSLYIAD 4498

Query: 1821 VCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
               +D +++ C A N +G       +IV+
Sbjct: 4499 AQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            HV P   +  + L+V  G      C  +G P P + W K   ++       +  + DG  
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDG-- 1224

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
            +L I      D   YTC A N  G
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAG 1248



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 5/84 (5%)

Query: 1769 VVEGSAARFDCKI-EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
            V+EG      C +  G P PE  W K+   + ++ +  +  D     SL I  V   D  
Sbjct: 901  VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG----SLHIERVQLQDGG 956

Query: 1828 KYTCKAVNSLGEATCTAELIVETM 1851
            +YTC A N  G    T  ++V  +
Sbjct: 957  EYTCVASNVAGTNNKTTSVVVHVL 980



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 7/85 (8%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR--ESRHFQIDYDEDGNCSLIISDVCG 1823
            ++ V+ G      C+++  P P + W K+ Q I     RH  +      + S+ I++   
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP-----SGSMKITETRT 1142

Query: 1824 DDDAKYTCKAVNSLGEATCTAELIV 1848
             D   Y C A N  G  T   +L V
Sbjct: 1143 SDSGMYLCVATNIAGNVTQAVKLNV 1167



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1813
            P +K   S    ++ V+   +A  +C   G P P   W KD Q + E  H +  +  +G 
Sbjct: 2869 PIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHK--FLSNGR 2926

Query: 1814 CSLIISDVCGDDDAKYTCKAVNSLGEA 1840
               I++     D  +Y C A N+ G A
Sbjct: 2927 ILQILNTQI-TDIGRYVCVAENTAGSA 2952



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)

Query: 1732 AEKLESEEDVSQAFLEAVAEEKP-HVKPYFSKTIRDLE---VVE--GSAARFDCKIEGYP 1785
            AE  ++ + V +A   A  ++K  H+  Y   +I   E   +VE   +     C   G P
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIP 3179

Query: 1786 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
             P + W K+ + I  S   ++     G   L I+     D   YTC A N  G+A
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRI-LSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 1/80 (1%)

Query: 1761 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1820
            S  +  L V+EG+     C+  G P P ++W K    +      ++     G   L IS 
Sbjct: 2200 SDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR-QLQISI 2258

Query: 1821 VCGDDDAKYTCKAVNSLGEA 1840
                D A Y+C A N  G A
Sbjct: 2259 AEKSDAALYSCVASNVAGTA 2278



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 3/72 (4%)

Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
            +V+  +     C+    P P + W+KD   +  S    I     G   L I     +D  
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI---LPGGRVLQIPRAKVEDAG 2844

Query: 1828 KYTCKAVNSLGE 1839
            +YTC AVN  GE
Sbjct: 2845 RYTCVAVNEAGE 2856



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 3/84 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            +V P      + L ++   +   +C  EG P P + W KD  ++    H +    E+G  
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDG-AVLAGNHARYSILENG-- 3766

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
             L I      D  +Y C A N+ G
Sbjct: 3767 FLHIQSAHVTDTGRYLCMATNAAG 3790



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 3/95 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            H  P       +L V+  +     C+  G P P + W K+  ++  S          G  
Sbjct: 3985 HEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-- 4042

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             L IS    +D   Y C A N  G A    +L V+
Sbjct: 4043 -LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 16/90 (17%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-------I 1818
            ++ VV       +C+++G P P++ WFKD + +         +  D N  L+       +
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPL---------FLGDPNVELLDRGQVLHL 1512

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             +   +D  +Y C   N+ G+     +L +
Sbjct: 1513 KNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 3/70 (4%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+  +  + +CK  G P P + W+KD++ +  S    + +   G   + I      D   
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNRGQI-IDIESAQISDAGI 1988

Query: 1829 YTCKAVNSLG 1838
            Y C A+NS G
Sbjct: 1989 YKCVAINSAG 1998


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score =  171 bits (434), Expect = 5e-42
 Identities = 181/790 (22%), Positives = 294/790 (37%), Gaps = 114/790 (14%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P  L +  GA  +     +G P+P +TWH++GQ +T      L+   R T  L +     
Sbjct: 2311 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR-----LENNSRATRVLRVR---- 2361

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
             D G YTC A + +GA                     + K+   R  AP     P+I G 
Sbjct: 2362 -DAGLYTCLAESPAGA---------------------IEKSFRVRVQAP-----PNIVGP 2394

Query: 159  CPPKFATKL--GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
              P+F   L  G++V++        C +   P P++TW +  + LQ  A     E+   +
Sbjct: 2395 RGPRFVVGLAPGQLVLE--------CSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--R 2444

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-----------SANRSFVRETK 265
             L++  ++  D G Y+C   N +G  S++  + I  +            S N++ +   +
Sbjct: 2445 FLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQ 2504

Query: 266  ATNSDV-----RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
            A          RK+   +  +  + + L   +        Q  G     A++     R+ 
Sbjct: 2505 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQG 2564

Query: 321  KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR--------APGLGVLSPSGEERK 372
            +     + P  AP    L  T+ +  L        P+           L      G  R 
Sbjct: 2565 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2624

Query: 373  RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
             P+     T P  Q     + VVS        +        P          V     V 
Sbjct: 2625 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVV 2684

Query: 433  FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
              C  +GIP P V+W   G  +  +      Y  + S  L + +A    +G Y+C+A N+
Sbjct: 2685 LTCHSTGIPAPTVSWSKAGAQLGARGSG---YRVSPSGALEIGQALPIHAGRYTCSARNS 2741

Query: 493  QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
             G       L V+   V++  PS    + +      ++ +L C   G P P ITW   G 
Sbjct: 2742 AGVAHKHVFLTVQASPVVKPLPSVVRAVAE------EEVLLPCEASGIPRPTITWQKEGL 2795

Query: 553  PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 612
             +    ST      +L I  A PED G Y C+A+N+ G       + V            
Sbjct: 2796 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ----------- 2844

Query: 613  LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHF 671
                      P+   GL DL   +GS   +  +  G+P P + W  +G  +  +E  F  
Sbjct: 2845 --------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI 2896

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 731
            +  G    L ++ +  +D GTYTC A N+ G  R +  LT+        P F + P   +
Sbjct: 2897 QPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRS 2948

Query: 732  ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791
              LG  + + CA  G P P + W  + + + +      V + +   TL    V    +G 
Sbjct: 2949 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSEQDGGSTLQRAAVSREDSGT 3003

Query: 792  YEILLKNRVG 801
            Y    +NRVG
Sbjct: 3004 YVCWAENRVG 3013



 Score =  169 bits (429), Expect = 2e-41
 Identities = 197/775 (25%), Positives = 290/775 (37%), Gaps = 145/775 (18%)

Query: 45   KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
            K  +T   E      P P + W+++GQP+T   R  +   +     L I      D G+Y
Sbjct: 1461 KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQV---LGEGRLLQIQPTQVSDSGRY 1517

Query: 105  TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
             C ATN +G       + ++         P + + +GD  +A  + +R     E      
Sbjct: 1518 LCVATNVAGEDDQDFNVLIQ--------VPPMFQKVGDFSAAFEILSRE----EEARGGV 1565

Query: 165  TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
            T+   +V  E       C     P P +TW + + PL     VSV +  G +VL+I  V 
Sbjct: 1566 TEYREIV--ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ--GGRVLQIPLVR 1621

Query: 225  QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESK 284
             ++ G Y+C   N  G+  +  EL            V        D  + V  V    S 
Sbjct: 1622 AENAGRYSCKASNEVGEDWLHYEL-----------LVLTPPVILGDTEELVEEVTVNASS 1670

Query: 285  LDSLEAAAKSKNCSSPQRGGSPP---WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
              SL+          P  G   P   W  N  P  P                 +P LQ  
Sbjct: 1671 TVSLQC---------PALGNPVPTISWLQNGLPFSP-----------------SPRLQVL 1704

Query: 342  SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR 401
                 LQ +  +    A  + V        ++    R    P R  GL  + V +     
Sbjct: 1705 EDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLR-VQVPPRIAGLDLEQVTAIL--- 1760

Query: 402  RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461
                                      N +V   C+V   P PEV W+ +   +   E   
Sbjct: 1761 --------------------------NSSVSLPCDVHAHPNPEVTWYKDSQALSLGE--- 1791

Query: 462  EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521
            EV+   G+H L L +AR  DSG Y+C A NA G+       ++ +L+V+ V P+F    +
Sbjct: 1792 EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR-----DQKLVQLSVL-VPPAFRQAPR 1845

Query: 522  ---DCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPE 576
               D  ++  G   VL C     P P +TW  +GQP+  A R+    G   L IQ+A   
Sbjct: 1846 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 1905

Query: 577  DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
            D G Y+C   N  G+   +  +TV            +P     P      Q       + 
Sbjct: 1906 DKGLYSCKVSNVAGEAVRTFTLTVQ-----------VPPTFENPKTETVSQ-------VA 1947

Query: 637  GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
            GS + +T  VSG P P V WL +   ++ S       RG +  L +  + P   GTYTC 
Sbjct: 1948 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCV 2005

Query: 697  AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL--------GQSVLISCAIAGDP 748
            A N+  E R   V+ V           +  PR  ++ +        GQ V + C   G P
Sbjct: 2006 AENTQAEARKDFVVAV-----------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP 2054

Query: 749  FPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
             P V WL+DG  L +D G H       D  +LVLK ++   AG Y  +  N  GE
Sbjct: 2055 PPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRASDAGAYTCVAHNPAGE 2107



 Score =  148 bits (373), Expect = 6e-35
 Identities = 110/380 (28%), Positives = 175/380 (46%), Gaps = 44/380 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C+  G P+P + W  +G PV   EG   +     S  L +     +D+GTY+CTA NA G
Sbjct: 2868 CKARGSPEPNITWDKDGQPVSGAEGKFTIQP---SGELLVKNLEGQDAGTYTCTAENAVG 2924

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
            +      L +       V P F+++  D ++  G    L+C+ RG+P PRI W +N +P+
Sbjct: 2925 RARRRVHLTIL------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV 2978

Query: 555  QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
                S  + G + L       ED GTY C AEN +G+    ++V V E            
Sbjct: 2979 TEGVSEQDGG-STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE------------ 3025

Query: 615  VAPSKPTAPIFLQG--LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
                   AP+ LQG   S L    G  + +   V G+P P++ W+ +G  ++ S   H  
Sbjct: 3026 -------APV-LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL 3077

Query: 673  QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 732
            Q G   SL I     +D G Y C A N  G  +   +L +Q     + P F  +P+ +T 
Sbjct: 3078 QNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-----SAPVFQVEPQDMTV 3129

Query: 733  SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
              G  V + C   G+P PT+ WL+ G+ L + +     L +    +L L+ V+   AG Y
Sbjct: 3130 RSGDDVALRCQATGEPTPTIEWLQAGQPL-RASRRLRTLPDG---SLWLENVETGDAGTY 3185

Query: 793  EILLKNRVGECSCQVSLMLQ 812
            + +  N +G  + +  L+++
Sbjct: 3186 DCVAHNLLGSATARAFLVVR 3205



 Score =  145 bits (366), Expect = 4e-34
 Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 44/405 (10%)

Query: 412  AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            A P  +  P        + V   CE SGIP+P + W  EG  V     +    +      
Sbjct: 2755 ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST----QVLPGGQ 2810

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L +  A   D+G Y C A N+ G       L      V++V P   + L D +  EG   
Sbjct: 2811 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRL------VVQVPPVIENGLPDLSTTEGSHA 2864

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA-ELHIQDALPEDHGTYTCLAENALG 590
             L C  RG+P P ITW  +GQP+  A        + EL +++   +D GTYTC AENA+G
Sbjct: 2865 FLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2924

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
            +      +T+           +LPV  + P          D  +  G ++ +     G+P
Sbjct: 2925 RARRRVHLTI----------LVLPVFTTLP---------GDRSLRLGDRLWLRCAARGSP 2965

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
             P + W  N   + E      EQ G   +L    V  ED+GTY C A N  G  RTQAV 
Sbjct: 2966 TPRIGWTVNDRPVTEGVS---EQDGGS-TLQRAAVSREDSGTYVCWAENRVG--RTQAVS 3019

Query: 711  TVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
             V   H    P    +  S +   +G S+ + C + GDP P +HW++DG  L + +    
Sbjct: 3020 FV---HVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-RGSHLRH 3075

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
             LQN    +L + + +   AG+Y+ L +N +G     V L+LQ++
Sbjct: 3076 QLQNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 3117



 Score =  138 bits (347), Expect = 6e-32
 Identities = 185/745 (24%), Positives = 273/745 (36%), Gaps = 117/745 (15%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCG---IRG 87
            E PA    P NL +     A       G P+P V W ++GQ +     F L  G   +  
Sbjct: 2571 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD----FRLQQGAYRLLP 2626

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
            + +L++ A   +D  ++ C  +N  G      ++TV                        
Sbjct: 2627 SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----------------------- 2663

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                 P+I  +      T +  VV+        +C  TG P P V+W K    L   AR 
Sbjct: 2664 ---VPPTIADDQTDFTVTMMAPVVL--------TCHSTGIPAPTVSWSKAGAQL--GARG 2710

Query: 208  SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------LDSANRSFV 261
            S    +    LEI        G YTC   N +G A     L++Q       L S  R+  
Sbjct: 2711 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 2770

Query: 262  RETKATNSDV----------RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
             E      +           +KE  NV +  S         +  + S    G     A N
Sbjct: 2771 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 2830

Query: 312  SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA--ARVQPEPR------------ 357
            S      +++L   +  P      P L  T  S       AR  PEP             
Sbjct: 2831 SAGSAMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 2889

Query: 358  APGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFE 417
            A G   + PSGE   +    + A   T      +++ V +A  RR+ +        P F 
Sbjct: 2890 AEGKFTIQPSGELLVKNLEGQDAGTYT----CTAENAVGRA-RRRVHLT---ILVLPVFT 2941

Query: 418  SKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKA 477
            + P  + ++    +  RC   G P P + W +   PV   EG   V E  G   L     
Sbjct: 2942 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EG---VSEQDGGSTLQRAAV 2996

Query: 478  RTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
               DSGTY C A N  G+      + V+   V++   +FS +++      G    L C V
Sbjct: 2997 SREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ-GEAFSYLVEPV----GGSIQLDCVV 3051

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
            RG PVP I W+ +G P++ +    +     L I     +D G Y CLAEN +G       
Sbjct: 3052 RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA----- 3106

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                      K   +L +     +AP+F     D+ V  G  V +  Q +G P P + WL
Sbjct: 3107 ----------KKVVILVL----QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 3152

Query: 658  HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPH 716
              G  ++ S        G   SL ++ V   D GTY C A N  G    +A L V+ EP 
Sbjct: 3153 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209

Query: 717  D--GTQPWFISKPRSVTASLGQSVL 739
               G+    I+  +   A+L  SV+
Sbjct: 3210 GSWGSMTGVINGRKFGVATLNTSVM 3234



 Score =  134 bits (337), Expect = 8e-31
 Identities = 186/829 (22%), Positives = 286/829 (34%), Gaps = 196/829 (23%)

Query: 58   GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
            G P P + W +NG+P        +    +GT +L I  V  +  G + C+ATN +G    
Sbjct: 524  GSPVPTIQWLQNGRPAEELAG--VQVASQGT-TLHIDHVELDHSGLFACQATNEAGTAGA 580

Query: 118  TVELTVEGSFAK-----QLGQ----------------PVVSKTLGDRFSAPAVE---TRP 153
             VE++V G +A       +GQ                P V +  G     P VE   +  
Sbjct: 581  EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPG 640

Query: 154  SIWGE-----------------------------------------------CPPKFATK 166
            S+WGE                                                PP     
Sbjct: 641  SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPG 700

Query: 167  LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
                 V E       C  +G P P V+W KG+ P+     V+VS     +VL I      
Sbjct: 701  PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLS 758

Query: 227  DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLD 286
            D G Y C+  N +G   +   L +                          NV  + +   
Sbjct: 759  DAGSYRCVASNVAGSTELRYGLRV--------------------------NVPPRITLPP 792

Query: 287  SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSS-- 344
            SL           P    +P     +    P  + +     +P +   TP LQ       
Sbjct: 793  SL---------PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV 843

Query: 345  ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG--LGSQDVVSKAANRR 402
            +TL +AR     R   + V S  GE+R      +        P   LG +  VS  AN  
Sbjct: 844  LTLASARASDSGRYSCVAV-SAVGEDR------QDVVLQVHMPPSILGEELNVSVVANES 896

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
            + +E Q  +                            +P P ++W+ +G P+  + G   
Sbjct: 897  VALECQSHA----------------------------MPPPVLSWWKDGRPLEPRPG--- 925

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V+  A    L + +A   D+G Y+C A N  G+    + L V    V  +  S +  ++ 
Sbjct: 926  VHLSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVR- 984

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHG 579
                EG    L C  RG P P+I+W  +GQP+    +  +   A    L++  A     G
Sbjct: 985  ----EGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 1040

Query: 580  TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
            TYTC   N +G  S    + VH           +P   + P  P      + + V+    
Sbjct: 1041 TYTCECSNVVGNSSQDLQLEVH-----------VPPQIAGPREP-----PTQVSVVQDGV 1084

Query: 640  VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             T+    +G PPP V W  +G  +        + +G   SL ++      TG Y+C A N
Sbjct: 1085 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG--QSLHVERAQAAHTGRYSCVAEN 1142

Query: 700  SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
             AG    +  L+V  P +      +    ++TA+L   + + C   G P P + W R   
Sbjct: 1143 LAGRAERKFELSVLVPPELIGD--LDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR--- 1197

Query: 760  ALCKDTGHFEVLQNEDVFTLV------LKKVQPWHAGQYEILLKNRVGE 802
                  G   V   ED + L       + + Q   +G Y  L  N  GE
Sbjct: 1198 ------GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 1240



 Score =  128 bits (322), Expect = 5e-29
 Identities = 110/377 (29%), Positives = 156/377 (41%), Gaps = 44/377 (11%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V     V+  CE  G+P P V+W  +G P+  Q       E   S  L L      DSGT
Sbjct: 2227 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS-----LEQGPS--LQLEAVGAGDSGT 2279

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            YSC A +  G+    + L V     +E     S    + ++  G    L C  +GTP P 
Sbjct: 2280 YSCVAVSEAGEARRHFQLTVMEPPHIED----SGQPTELSLTPGAPMELLCDAQGTPQPN 2335

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
            ITW  +GQ +    +   A    L ++DA     G YTCLAE+  G +  S  V V    
Sbjct: 2336 ITWHKDGQALTRLENNSRA-TRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRVQA-- 2387

Query: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
                     P     P  P F+ GL+        Q+ +   V   P P++ W  +G  +Q
Sbjct: 2388 ---------PPNIVGPRGPRFVVGLAP------GQLVLECSVEAEPAPKITWHRDGIVLQ 2432

Query: 665  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
            E     F +RG    L +Q +   D+G Y+C A N+AG       + +      T P   
Sbjct: 2433 EDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-----TVPTIR 2485

Query: 725  SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784
            S P +V  S+ Q+ L+ C   G P P V W +D   L   +  FE+L      +L ++ V
Sbjct: 2486 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPV 2542

Query: 785  QPWHAGQYEILLKNRVG 801
                AG Y  L  N  G
Sbjct: 2543 LAQDAGHYLCLASNSAG 2559



 Score =  128 bits (321), Expect = 6e-29
 Identities = 116/443 (26%), Positives = 177/443 (39%), Gaps = 43/443 (9%)

Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
           V+ +C  SG+P P+V W  +  PV      ++V ED     L +  +   D G Y C A 
Sbjct: 235 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG--QVLRITGSHVGDEGRYQCVAF 292

Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
           +  GQ +  + L+V         P+   S+   + AV+E     L C  RG P P ITW 
Sbjct: 293 SPAGQQARDFQLRVH------APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 346

Query: 549 LNGQPIQYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
            +G  +  +       G  +L +  A   D G YTC A NA+G            +K++R
Sbjct: 347 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA----------EKATR 396

Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
              Y+ P        P  +      K + G  V +     G+P P + W H G  + ES 
Sbjct: 397 LDVYVPPTIEGAGGRPYVV------KAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN 450

Query: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
           +   E  G+   L ++      +G Y+C A + AGE   Q  + VQ P    Q       
Sbjct: 451 ESRLETDGSV--LRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVP---PQLLVAEGL 505

Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
             VT  +GQ + + C  +G P PT+ WL++G+   +  G     Q     TL +  V+  
Sbjct: 506 GQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT---TLHIDHVELD 562

Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARA---LPRGREPASCEDLCGGGVGAD----- 839
           H+G +     N  G    +V + +    A     +P G+     E         D     
Sbjct: 563 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 622

Query: 840 GGGSDRYGSLRPGWPARGQGWLE 862
           G G+     L  GW + G  W E
Sbjct: 623 GWGAHPKPPLVEGWCSPGSLWGE 645



 Score =  126 bits (316), Expect = 2e-28
 Identities = 105/399 (26%), Positives = 166/399 (41%), Gaps = 47/399 (11%)

Query: 413  FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
            FP  ES   +  V+E       CE  G+P P+++W  +G P+  +   ++ +  A    L
Sbjct: 973  FPLRES--HTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVSAVGRLL 1029

Query: 473  CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE---RLAVMEVAPSFSSVLKDCAVIEGQ 529
             L +A+    GTY+C  SN  G  S    L+V    ++A     P+  SV++D       
Sbjct: 1030 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVA---- 1085

Query: 530  DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV------AELHIQDALPEDHGTYTC 583
               L+C+  G P P +TW  +GQP+       E G+        LH++ A     G Y+C
Sbjct: 1086 --TLECNATGKPPPTVTWERDGQPV-----GAELGLQLQNQGQSLHVERAQAAHTGRYSC 1138

Query: 584  LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
            +AEN  G             ++ RK E  + V P        L  L+++     S +T+ 
Sbjct: 1139 VAENLAG-------------RAERKFELSVLVPPELIGD---LDPLTNITAALHSPLTLL 1182

Query: 644  VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             +  G PPP + W      +   ED +    G    L + +   +D+G Y+C A N AGE
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWM--LKMTQTQEQDSGLYSCLASNEAGE 1240

Query: 704  VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
             R    + V  P              +    GQ+  + C + G P P + W +DG+ L +
Sbjct: 1241 ARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLAR 1297

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
               H     + D   L + +     AG Y  +  N VGE
Sbjct: 1298 GDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGE 1333



 Score =  124 bits (311), Expect = 9e-28
 Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 53/433 (12%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P  E  P ++ V EN +V   C  SG+P P+V+WF    PV    G   V        L 
Sbjct: 695  PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTVSVDGRVLR 751

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            + +A+  D+G+Y C ASN  G     + L+V     + + PS         V+      L
Sbjct: 752  IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPG-----PVLVNTPVRL 806

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
             C+  G P P + WL +G P+  A +       G   L +  A   D G Y+C+A +A+G
Sbjct: 807  TCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVG 866

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
            +      + VH                     P  L    ++ V+    V +  Q    P
Sbjct: 867  EDRQDVVLQVH-------------------MPPSILGEELNVSVVANESVALECQSHAMP 907

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
            PP + W  +G  ++     H      +  L +      D G YTCEA N AG        
Sbjct: 908  PPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGR------- 958

Query: 711  TVQEPHDGTQPWF-----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
               E H     W      + +  ++T   G    +SC   G PFP + W +DG+ L    
Sbjct: 959  --SEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL---P 1013

Query: 766  GHFEVLQNEDVF--TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR 823
            G    LQ+       L L + Q    G Y     N VG  S  + L +      A P  R
Sbjct: 1014 GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP--R 1071

Query: 824  EPASCEDLCGGGV 836
            EP +   +   GV
Sbjct: 1072 EPPTQVSVVQDGV 1084



 Score =  119 bits (298), Expect = 3e-26
 Identities = 109/396 (27%), Positives = 163/396 (41%), Gaps = 40/396 (10%)

Query: 423  QEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
            +E+ EN      C+ + IP P++ W+ E  P+   +   EV    G   L +   R  ++
Sbjct: 1569 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD---EVSVLQGGRVLQIPLVRAENA 1625

Query: 483  GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
            G YSC ASN  G+    + L V  L    +      ++++  V       LQC   G PV
Sbjct: 1626 GRYSCKASNEVGEDWLHYELLV--LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPV 1683

Query: 543  PRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            P I+WL NG P   +      E G   L +  A   D  +Y C+AEN  G          
Sbjct: 1684 PTISWLQNGLPFSPSPRLQVLEDGQV-LQVSTAEVADAASYMCVAENQAG---------- 1732

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                    +E L  +    P     L  L  +  +  S V++   V  +P PEV W  + 
Sbjct: 1733 -------SAEKLFTLRVQVPPRIAGLD-LEQVTAILNSSVSLPCDVHAHPNPEVTWYKDS 1784

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
              +   E+  F   GT H+L +      D+G YTCEA N+AG  +    L+V  P     
Sbjct: 1785 QALSLGEEV-FLLPGT-HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP----- 1837

Query: 721  PWFISKPR----SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
            P F   PR    +V   +G   ++SC     P PTV W +DG+ L       + L+    
Sbjct: 1838 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVL-AQRTQALRGGQ- 1895

Query: 777  FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              L +++ Q    G Y   + N  GE     +L +Q
Sbjct: 1896 -RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 1930



 Score =  119 bits (297), Expect = 4e-26
 Identities = 99/385 (25%), Positives = 157/385 (40%), Gaps = 45/385 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C V   P P++ W  +G  +  QE +   + + G  +L L    T DSG YSCTA NA G
Sbjct: 2412 CSVEAEPAPKITWHRDGIVL--QEDAHTQFPERG-RFLQLQALSTADSGDYSCTARNAAG 2468

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
              S ++ +++  +  +   P   +V  +      Q  +L C   G P P ++W  +  P+
Sbjct: 2469 STSVAFRVEIHTVPTIRSGPPAVNVSVN------QTALLPCQADGVPAPLVSWRKDRVPL 2522

Query: 555  QYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
                   E      L IQ  L +D G Y CLA N+ G              S R+   L 
Sbjct: 2523 DPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG--------------SDRQGRDLR 2568

Query: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
             + P     P      S+L +   +   +  + SG+P P V+W  +G ++    DF  +Q
Sbjct: 2569 VLEP-----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQ 2619

Query: 674  RGTQ----HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
               +    ++L +    P+D+  + C   N  GE      +TV  P     P        
Sbjct: 2620 GAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVP-----PTIADDQTD 2674

Query: 730  VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             T ++   V+++C   G P PTV W + G  L      + V  +     L + +  P HA
Sbjct: 2675 FTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHA 2731

Query: 790  GQYEILLKNRVGECSCQVSLMLQNS 814
            G+Y    +N  G     V L +Q S
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQAS 2756



 Score =  118 bits (296), Expect = 5e-26
 Identities = 106/388 (27%), Positives = 155/388 (39%), Gaps = 48/388 (12%)

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            +P    +     ++  C+  G P+P + W  +G  + R E +                 R
Sbjct: 2310 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR----------VLR 2359

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
             RD+G Y+C A +  G +  S+ ++V+    + V P     +   A   GQ  VL+CSV 
Sbjct: 2360 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLA--PGQ-LVLECSVE 2415

Query: 539  GTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
              P P+ITW  +G  +Q  A +        L +Q     D G Y+C A NA G  S +  
Sbjct: 2416 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 2475

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
            V +H                   T P    G   + V       +  Q  G P P V W 
Sbjct: 2476 VEIH-------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWR 2516

Query: 658  HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
             +   +   S  F     G   SL IQ V  +D G Y C A NSAG  R    L V EP 
Sbjct: 2517 KDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP- 2572

Query: 717  DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKDTGHFEVLQNE 774
                P     P ++T +     L+ C  +G P P V W +DG+ L      G + +L + 
Sbjct: 2573 ----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2628

Query: 775  DVFTLVLKKVQPWHAGQYEILLKNRVGE 802
                L+L    P  + Q+E ++ N VGE
Sbjct: 2629 ---ALLLTAPGPQDSAQFECVVSNEVGE 2653



 Score =  117 bits (293), Expect = 1e-25
 Identities = 108/407 (26%), Positives = 169/407 (41%), Gaps = 39/407 (9%)

Query: 414  PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            P  E++   + +K  + QT    C V+G P+P++ WF +G P+ R +     +       
Sbjct: 1253 PSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVL 1309

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L +L+A    +G YSC A+NA G+ +  + L V  LA   +  +  S  ++  V      
Sbjct: 1310 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNPI 1368

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
             L C     P P ITW+ +G P + +R+     G   L I +A  ED G YTC+  N LG
Sbjct: 1369 SLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1428

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
                       E   +   E L+P + SK   P+   G+ ++K    S +T+  +    P
Sbjct: 1429 -----------EAVKNYHVEVLIPPSISKDD-PLGEVGVKEVKTKVNSTLTLECESWAVP 1476

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE------V 704
            PP + W  +G  +  S     +  G    L IQ     D+G Y C A N AGE      V
Sbjct: 1477 PPTIRWYKDGQPVTPSS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV 1534

Query: 705  RTQAVLTVQEPHDGTQPW-FISKPRSVTASL--------GQSVLISCAIAGDPFPTVHWL 755
              Q     Q+  D +  +  +S+       +             + C     P P + W 
Sbjct: 1535 LIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWY 1594

Query: 756  RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
            R+ + L        VLQ   V  + L + +  +AG+Y     N VGE
Sbjct: 1595 REDQPLSAG-DEVSVLQGGRVLQIPLVRAE--NAGRYSCKASNEVGE 1638



 Score =  117 bits (292), Expect = 1e-25
 Identities = 105/406 (25%), Positives = 158/406 (38%), Gaps = 50/406 (12%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P   S P +  V  NQT    C+  G+P P V+W  +  P+  +    E+  +     L 
Sbjct: 2482 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS---LR 2538

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            +     +D+G Y C ASN+ G       L+V  L    +APS S++     +      +L
Sbjct: 2539 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRV--LEPPAIAPSPSNL----TLTAHTPALL 2592

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDAL------PEDHGTYTCLAEN 587
             C   G+P P + W  +GQ + +     + G   L   +AL      P+D   + C+  N
Sbjct: 2593 PCEASGSPKPLVVWWKDGQKLDF---RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2649

Query: 588  ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
             +G+      VTVH                     P      +D  V   + V +T   +
Sbjct: 2650 EVGEAHRLYQVTVH-------------------VPPTIADDQTDFTVTMMAPVVLTCHST 2690

Query: 648  GNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
            G P P V W   G ++      +     G   +L I +  P   G YTC A NSAG    
Sbjct: 2691 GIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAGVAHK 2747

Query: 707  QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766
               LTVQ       P     P  V A   + VL+ C  +G P PT+ W ++G  +     
Sbjct: 2748 HVFLTVQ-----ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 2802

Query: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              +VL       L +    P  AG Y  + KN  G    +  L++Q
Sbjct: 2803 -TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2844



 Score =  115 bits (289), Expect = 3e-25
 Identities = 92/379 (24%), Positives = 158/379 (41%), Gaps = 42/379 (11%)

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
            +  + V   C V G P   V+W  +G P+   + ++        H L + K +  D+G +
Sbjct: 2135 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL---HGSGHTLRISKVQLADAGIF 2191

Query: 486  SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 545
            +C A++  G    ++TLQV+   V+E          D  V+ G    L C  RG P+P +
Sbjct: 2192 TCVAASPAGVADRNFTLQVQVPPVLEPV----EFQNDVVVVRGSLVELPCEARGVPLPLV 2247

Query: 546  TWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
            +W+ +G+P+     + E G   L ++     D GTY+C+A +  G+      +TV E   
Sbjct: 2248 SWMKDGEPL--LSQSLEQG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2304

Query: 606  SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
               S         +PT         +L +  G+ + +     G P P + W  +G  +  
Sbjct: 2305 IEDS--------GQPT---------ELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 2347

Query: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             E+         +S   + +   D G YTC A + AG +     + VQ P +   P    
Sbjct: 2348 LEN---------NSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP---R 2395

Query: 726  KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
             PR V       +++ C++  +P P + W RDG  L +D  H +  +      L L+ + 
Sbjct: 2396 GPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRF--LQLQALS 2452

Query: 786  PWHAGQYEILLKNRVGECS 804
               +G Y    +N  G  S
Sbjct: 2453 TADSGDYSCTARNAAGSTS 2471



 Score =  114 bits (285), Expect = 9e-25
 Identities = 105/389 (26%), Positives = 167/389 (42%), Gaps = 45/389 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            CE  GIP P + WF    PV   E   + Y  AG   L + + + +DSG YSC ASN  G
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPGE---DTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1239

Query: 495  QLSCSWTLQVERLAVMEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
            +   +++++V       V PS  +  + +   V++GQ   L C+V G P P++TW  +G+
Sbjct: 1240 EARRNFSVEV------LVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGR 1293

Query: 553  PIQY--ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
            P+    A      GV  L +  A     G Y+C+A NA+G           EK    +  
Sbjct: 1294 PLARGDAHHISPDGVL-LQVLQANLSSAGHYSCIAANAVG-----------EKTKHFQLS 1341

Query: 611  YLLPVAPSKPTAPIFLQGLSD-----LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
             LL        AP  L G  D     + V   + +++  +    P P + W+ +G   + 
Sbjct: 1342 VLL--------APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEA 1393

Query: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPH-DGTQPWF 723
            S +      GT H L I     ED G YTC   N  GE V+   V  +  P      P  
Sbjct: 1394 SRNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLG 1451

Query: 724  ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
                + V   +  ++ + C     P PT+ W +DG+ +   +   +VL    +  L ++ 
Sbjct: 1452 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPV-TPSSRLQVLGEGRL--LQIQP 1508

Query: 784  VQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             Q   +G+Y  +  N  GE     ++++Q
Sbjct: 1509 TQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1537



 Score =  110 bits (274), Expect = 2e-23
 Identities = 78/289 (26%), Positives = 125/289 (43%), Gaps = 26/289 (8%)

Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
           V E+  V+  CE  G+P P + WF +G  +     S +V    G   L L +A++ D+G 
Sbjct: 323 VMEDHLVQLLCEARGVPTPNITWFKDGALLPT---STKVVYTRGGRQLQLGRAQSSDAGV 379

Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
           Y+C ASNA G    +  L V     +E A     V+K    + G+   L+C  RG P P 
Sbjct: 380 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVK---AVAGRPVALECVARGHPSPT 436

Query: 545 ITWLLNGQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
           ++W   G P+  +  S  E   + L ++       G Y+C+A +  G+      V V   
Sbjct: 437 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV- 495

Query: 604 KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
                           P   +  +GL  +  + G  + +  Q SG+P P + WL NG   
Sbjct: 496 ----------------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 539

Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
           +E        +GT  +L I  V  + +G + C+A N AG    +  ++V
Sbjct: 540 EELAGVQVASQGT--TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 586



 Score =  106 bits (264), Expect = 2e-22
 Identities = 121/509 (23%), Positives = 192/509 (37%), Gaps = 60/509 (11%)

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
            + K N T+   CE   +P P + W+ +G PV      ++V  +     L +   +  DSG
Sbjct: 1459 KTKVNSTLTLECESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEG--RLLQIQPTQVSDSG 1515

Query: 484  TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA--------------VIEGQ 529
             Y C A+N  G+    + + ++   + +    FS+  +  +              ++E  
Sbjct: 1516 RYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 1575

Query: 530  DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
               L C     P P +TW    QP+      +   G   L I     E+ G Y+C A N 
Sbjct: 1576 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNE 1635

Query: 589  LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL----QGLSDLKVMDGSQVTMTV 644
            +G+     W+            Y L V     T P+ L    + + ++ V   S V++  
Sbjct: 1636 VGE----DWL-----------HYELLVL----TPPVILGDTEELVEEVTVNASSTVSLQC 1676

Query: 645  QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
               GNP P + WL NG     S      + G    +   EV   D  +Y C A N AG  
Sbjct: 1677 PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV--ADAASYMCVAENQAGSA 1734

Query: 705  RTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
                 L VQ P     P         VTA L  SV + C +   P P V W +D +AL  
Sbjct: 1735 EKLFTLRVQVP-----PRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL 1789

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL-MLQNSSARALPRG 822
                 EV       TL L + +   +G Y     N  G     V L +L   + R  PRG
Sbjct: 1790 GE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRG 1846

Query: 823  REPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH 882
             + A    +  G        +D        W   GQ  +  +  + +RG  +  ++  Q 
Sbjct: 1847 PQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 1904

Query: 883  TEEAIRQQEVEQLDFRDLLGKKVSTKTLS 911
            +++ +   +V      ++ G+ V T TL+
Sbjct: 1905 SDKGLYSCKVS-----NVAGEAVRTFTLT 1928



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 107/408 (26%), Positives = 149/408 (36%), Gaps = 33/408 (8%)

Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
           +P   +    + V   C   G P P ++W  EG PV   E +    E  GS  L L    
Sbjct: 411 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVA--ESNESRLETDGS-VLRLESPG 467

Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
              SG YSC AS+  G+    ++++V+    + VA     V      I GQ   L C   
Sbjct: 468 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQAS 523

Query: 539 GTPVPRITWLLNGQPIQYARSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
           G+PVP I WL NG+P +       A     LHI     +  G + C A N  G       
Sbjct: 524 GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE 583

Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPI-----FLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
           V+VH +            AP     PI       +  S         V         PP 
Sbjct: 584 VSVHGE-----------WAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPL 632

Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
              W   G+   E              L I++V   D G YTC A N AGE + +  L V
Sbjct: 633 VEGWCSPGSLWGEPTGIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV 691

Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
             P    +P  ++K     A    SV + C  +G P P V W +  + +    G   V  
Sbjct: 692 LVP-PNIEPGPVNKAVLENA----SVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTV 743

Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
           + D   L +++ Q   AG Y  +  N  G    +  L +       LP
Sbjct: 744 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP 791



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 100/383 (26%), Positives = 142/383 (37%), Gaps = 33/383 (8%)

Query: 435 CEVSGIPKPEVAWFL--EGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
           C   G PKP+V W       P+  Q G + V E+     L L      DSG Y C A+N 
Sbjct: 24  CGTHGTPKPQVTWRKGPSSEPLHGQPG-VAVLEEGS---LFLASVSPADSGDYECQATNE 79

Query: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAV--IEGQDFVLQCSVRGTPVPRITWL-- 548
            G  S    L      V+ V PS     +   V  + GQ   L+C   G PVP I WL  
Sbjct: 80  VGSTSRRAKL------VVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKD 133

Query: 549 --LNGQPIQYARSTCEAGVAELHIQDALPEDHGT-YTCLAENALGQVSCSAWVTVHEKKS 605
             L G P+ +A    + G  ++     L E     +  +     G+    A  +   K  
Sbjct: 134 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAP 193

Query: 606 -----SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD--GSQVTMTVQVSGNPPPEVIWLH 658
                +   ++  P A S P  P  L   +  +V+   G+ V +    SG P P+V W  
Sbjct: 194 WXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTK 253

Query: 659 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 718
           +   +      H + +     L I      D G Y C A++ AG+      L V  P   
Sbjct: 254 DRQPVLPGGP-HLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAP--- 309

Query: 719 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 778
              W  ++   V       V + C   G P P + W +DG  L   T   +V+       
Sbjct: 310 PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST---KVVYTRGGRQ 366

Query: 779 LVLKKVQPWHAGQYEILLKNRVG 801
           L L + Q   AG Y     N VG
Sbjct: 367 LQLGRAQSSDAGVYTCKASNAVG 389



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 95/414 (22%), Positives = 150/414 (36%), Gaps = 61/414 (14%)

Query: 429 QTVKFRCEVSGIPKPEVAWF----LEGTPVR----------RQEGSIEVYEDAGS-HYLC 473
           Q++   C+ +G P PE+ W     L G P+            Q G   + ++  S H+  
Sbjct: 112 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPR 171

Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFS-----SVL-----KDC 523
           +   R+   G      +    Q    W   +          +FS     SVL     ++ 
Sbjct: 172 IQPGRSGRRG----AQAGGSAQTKAPWXAGLAGFEQFPTPHAFSPPAPPSVLGAGAAQEV 227

Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTY 581
             + G D  LQC   G P P++ W  + QP+         +     L I  +   D G Y
Sbjct: 228 LGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRY 287

Query: 582 TCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG---LSDLKVMDGS 638
            C+A +  GQ +    + VH                    AP  + G     ++ VM+  
Sbjct: 288 QCVAFSPAGQQARDFQLRVH--------------------APPTIWGSNETGEVAVMEDH 327

Query: 639 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 698
            V +  +  G P P + W  +G  +  S    + + G Q  L +      D G YTC+A 
Sbjct: 328 LVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQ--LQLGRAQSSDAGVYTCKAS 385

Query: 699 NSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDG 758
           N+ G       L V  P   T      +P  V A  G+ V + C   G P PT+ W  +G
Sbjct: 386 NAVGAAEKATRLDVYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEG 443

Query: 759 KALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             + +     E     D   L L+      +G Y  +  +  GE   Q S+ +Q
Sbjct: 444 LPVAESN---ESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 494



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 60/394 (15%)

Query: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
           Q ++  C+ SG P P + W   G P     G     +    H   +       SG ++C 
Sbjct: 514 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH---IDHVELDHSGLFACQ 570

Query: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSV---LKDCAVIEGQDFVLQCS--------- 536
           A+N  G        +VE     E AP    V              F   C          
Sbjct: 571 ATNEAGTAGA----EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGA 626

Query: 537 ------VRGTPVPRITW-LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
                 V G   P   W    G P+ Y+          L I+     D G YTC A N  
Sbjct: 627 HPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP------PLQIEKVDLRDEGIYTCAATNLA 680

Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
           G+             S R+    + V P+    P+      +  V++ + VT+    SG 
Sbjct: 681 GE-------------SKREVALKVLVPPNIEPGPV------NKAVLENASVTLECLASGV 721

Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
           PPP+V W      +           G    L I++    D G+Y C A N AG    +  
Sbjct: 722 PPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 779

Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC-KDTGHF 768
           L V  P   T P  +  P  V       V ++C   G P PT+ WL+DG  +    T   
Sbjct: 780 LRVNVPPRITLPPSLPGPVLVNT----PVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGL 835

Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
           +V     V TL   +     +G+Y  +  + VGE
Sbjct: 836 QVFPGGRVLTLASARAS--DSGRYSCVAVSAVGE 867



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 59/214 (27%), Positives = 86/214 (40%), Gaps = 42/214 (19%)

Query: 33   PAFILPPRN----LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            PAF   PR     + ++ G  A         PEP VTW+++GQP+    R      +RG 
Sbjct: 1838 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQR---TQALRGG 1894

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              L I      D+G Y+C+ +N +G    T  LTV+               +   F  P 
Sbjct: 1895 QRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ---------------VPPTFENPK 1939

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
             ET   + G   P   T                C ++G P P VTWLK  +P++ SA   
Sbjct: 1940 TETVSQVAGS--PLVLT----------------CDVSGVPAPTVTWLKDRMPVESSAVHG 1981

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
            V  + G   L++  +     G YTC+  N   +A
Sbjct: 1982 VVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEA 2013



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 59/207 (28%), Positives = 83/207 (40%), Gaps = 42/207 (20%)

Query: 47  GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL---DCGIRGTFSLVIHAVHEEDRGK 103
           GA  + +    G P PQV W ++ QP+  GG  L    D  +     L I   H  D G+
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV-----LRITGSHVGDEGR 286

Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
           Y C A + +G +    +L V                      AP     P+IWG      
Sbjct: 287 YQCVAFSPAGQQARDFQLRVH---------------------AP-----PTIWG------ 314

Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
           + + G V V E  + +  C+  G P P +TW K    L  S +V V  + G Q L++   
Sbjct: 315 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGGRQ-LQLGRA 372

Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSI 250
              D GVYTC   N  G A  +  L +
Sbjct: 373 QSSDAGVYTCKASNAVGAAEKATRLDV 399



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 35/220 (15%)

Query: 32   APAFIL-PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            AP F L     L ++EG         RG P P+++W ++GQP+   G  L      G   
Sbjct: 970  APVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL- 1028

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L +        G YTCE +N  G     ++L                           V 
Sbjct: 1029 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQL--------------------------EVH 1062

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
              P I G   P         VV++G +    C  TG+P P VTW +   P+   A + + 
Sbjct: 1063 VPPQIAGPREPPTQVS----VVQDG-VATLECNATGKPPPTVTWERDGQPV--GAELGLQ 1115

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             +N  Q L +        G Y+C+  N +G+A    ELS+
Sbjct: 1116 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1155



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 48/246 (19%)

Query: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
            A + + +T  +V    V   P+ +  AF      L    G + + +  VRG P P + W 
Sbjct: 3008 AENRVGRTQ-AVSFVHVKEAPVLQGEAFSY----LVEPVGGSIQLDCVVRGDPVPDIHWI 3062

Query: 68   RNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
            ++G P+     R  L  G     SL IH    +D G+Y C A N  G  +  V L ++  
Sbjct: 3063 KDGLPLRGSHLRHQLQNG-----SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-- 3115

Query: 127  FAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
                              SAP  +  P                + V+ G      C+ TG
Sbjct: 3116 ------------------SAPVFQVEPQ--------------DMTVRSGDDVALRCQATG 3143

Query: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
             P P + WL+   PL+ S R+          L +  V   D G Y C+  N  G A+  A
Sbjct: 3144 EPTPTIEWLQAGQPLRASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSATARA 3200

Query: 247  ELSIQG 252
             L ++G
Sbjct: 3201 FLVVRG 3206



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 57/238 (23%), Positives = 91/238 (38%), Gaps = 52/238 (21%)

Query: 16   SLSVDPSRVDSM-PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
            S+ V P  +  + PLT   A +  P  L  +            G P P + W R  +P++
Sbjct: 1154 SVLVPPELIGDLDPLTNITAALHSPLTLLCE----------AMGIPPPAIRWFRGEEPVS 1203

Query: 75   SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLG 132
             G    L   + G + L +    E+D G Y+C A+N  G   R  +VE+ V  S   +  
Sbjct: 1204 PGEDTYL---LAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDL 1260

Query: 133  QPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192
            + V+                                   V +GQ     C +TG PQP++
Sbjct: 1261 EEVIK----------------------------------VLDGQTAHLMCNVTGHPQPKL 1286

Query: 193  TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            TW K   PL       +S      +L++   N    G Y+C+  N  G+ +   +LS+
Sbjct: 1287 TWFKDGRPLARGDAHHISPDG--VLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1342



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 46/214 (21%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG----RFLLDCGIRGTFSLVIHAVHEE 99
            + EG   + +    G P P V W ++G P+        RF LD G     SLV+  +   
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-----SLVLKGLRAS 2092

Query: 100  DRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
            D G YTC A N +G  AR  TV + V                             P+I  
Sbjct: 2093 DAGAYTCVAHNPAGEDARLHTVNVLVP----------------------------PTI-- 2122

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
                + A   G +V + G++    C + G P   V+WLK  +PL  S R  +        
Sbjct: 2123 ---KQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HT 2177

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            L I  V   D G++TC+  + +G A  +  L +Q
Sbjct: 2178 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2211



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 56/236 (23%), Positives = 89/236 (37%), Gaps = 36/236 (15%)

Query: 15  TSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
           T+L+ +  R  ++ +   P     P N  + E A+   E    G P P V+W +  QP++
Sbjct: 677 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVS 736

Query: 75  SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
           S     +    R    L I      D G Y C A+N +G+ ++   L V           
Sbjct: 737 SWMGVTVSVDGR---VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN---------- 783

Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
                       P +   PS+ G  P    T +           R +C  TG P P + W
Sbjct: 784 ----------VPPRITLPPSLPG--PVLVNTPV-----------RLTCNATGAPSPTLMW 820

Query: 195 LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
           LK   P+ P+    +    G +VL +      D G Y+C+ V+  G+      L +
Sbjct: 821 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 40/197 (20%)

Query: 59   YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQ 116
            +P P +TW ++G P  +     L   + GT  L I    +ED G+YTC  TN  G   + 
Sbjct: 1377 FPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1433

Query: 117  VTVELTVEGSFAKQ--LGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE 174
              VE+ +  S +K   LG+  V +                          TK+   +  E
Sbjct: 1434 YHVEVLIPPSISKDDPLGEVGVKEV------------------------KTKVNSTLTLE 1469

Query: 175  GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
                   C+    P P + W K   P+ PS+R+ V  +   ++L+I      D G Y C+
Sbjct: 1470 -------CESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG--RLLQIQPTQVSDSGRYLCV 1520

Query: 235  VVNGSGKASMSAELSIQ 251
              N +G+      + IQ
Sbjct: 1521 ATNVAGEDDQDFNVLIQ 1537



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 36/213 (16%)

Query: 38   PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
            PP  + + +   A  E    G P P VTW R+GQP+  G    L    +G  SL +    
Sbjct: 1073 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQ-SLHVERAQ 1129

Query: 98   EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
                G+Y+C A N +G  +   EL                          +V   P + G
Sbjct: 1130 AAHTGRYSCVAENLAGRAERKFEL--------------------------SVLVPPELIG 1163

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
            +  P     L  +           C+  G P P + W +G  P+ P     +    G  +
Sbjct: 1164 DLDP-----LTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA--GGWM 1216

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            L++    + D G+Y+CL  N +G+A  +  + +
Sbjct: 1217 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1249



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 34/199 (17%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
            + +G TA     V G+P+P++TW ++G+P+  G    +     G    V+ A +    G 
Sbjct: 1266 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD--GVLLQVLQA-NLSSAGH 1322

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y+C A N  G +    +L+V       L  P +   LG    +   E             
Sbjct: 1323 YSCIAANAVGEKTKHFQLSV-------LLAPTI---LGGAEDSADEE------------- 1359

Query: 164  ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
                  V V         C+    P P +TW+K   P + S  + +    G   L+I   
Sbjct: 1360 ------VTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNA 1411

Query: 224  NQDDVGVYTCLVVNGSGKA 242
             ++D G YTC+V N  G+A
Sbjct: 1412 QKEDAGQYTCVVTNELGEA 1430



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 44/224 (19%)

Query: 31   EAPAFILPPRNLCIKEGATAK---FEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
            +AP  I+ PR      G        E  V   P P++TWHR+G  +            RG
Sbjct: 2386 QAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFP--ERG 2443

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
             F L + A+   D G Y+C A N +G+  V   + +                     + P
Sbjct: 2444 RF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH--------------------TVP 2482

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SAR 206
             + + P                V V   Q     C+  G P P V+W K  VPL P S R
Sbjct: 2483 TIRSGPP--------------AVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR 2528

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
              +  +     L I  V   D G Y CL  N +G      +L +
Sbjct: 2529 FEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 2569



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 51/279 (18%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            +P  K     V     +++LL C+ S  P  TI W   G  + T     +   G L    
Sbjct: 2756 SPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL---R 2812

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP----- 1211
            I  A PED G Y C+AKN AG A    ++ V   P  EN       +    + LP     
Sbjct: 2813 IAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG 2872

Query: 1212 -------------PVLGTESDATVKK--------------------------KPAPKTPP 1232
                         PV G E   T++                           +   +   
Sbjct: 2873 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 2932

Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
               + P     P D+ +R G+ + L     G+      W    + + E     V   + G
Sbjct: 2933 TILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG 2988

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            S L   A  +E  G Y    EN++G  QA   + V + P
Sbjct: 2989 STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 3027



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 41/195 (21%)

Query: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
            VRG P   V+W ++G P+    R LL        +L I  V   D G +TC A + +G  
Sbjct: 2146 VRGSPPIHVSWLKDGLPLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGV- 2201

Query: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
                    + +F  Q+  P            P +E         P +F      VVV  G
Sbjct: 2202 -------ADRNFTLQVQVP------------PVLE---------PVEFQND---VVVVRG 2230

Query: 176  QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
             +    C+  G P P V+W+K   PL     +S S + G   L++  V   D G Y+C+ 
Sbjct: 2231 SLVELPCEARGVPLPLVSWMKDGEPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVA 2284

Query: 236  VNGSGKASMSAELSI 250
            V+ +G+A    +L++
Sbjct: 2285 VSEAGEARRHFQLTV 2299



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 48/201 (23%)

Query: 57  RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
           RG P P +TW ++G  + +  + +     RG   L +      D G YTC+A+N  GA +
Sbjct: 336 RGVPTPNITWFKDGALLPTSTKVVYT---RGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 392

Query: 117 VTVEL------TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
               L      T+EG+     G+P V K +                           GR 
Sbjct: 393 KATRLDVYVPPTIEGAG----GRPYVVKAVA--------------------------GRP 422

Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
           V  E       C   G P P ++W    +P+  S   S  E +G  VL +    +   G+
Sbjct: 423 VALE-------CVARGHPSPTLSWHHEGLPVAESNE-SRLETDG-SVLRLESPGEASSGL 473

Query: 231 YTCLVVNGSGKASMSAELSIQ 251
           Y+C+  + +G+A +   + +Q
Sbjct: 474 YSCVASSPAGEAVLQYSVEVQ 494



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 61/259 (23%), Positives = 96/259 (37%), Gaps = 54/259 (20%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQD----VHVAEGKKLLLQCQVSSDPPATIIWT 1132
            C+  +A   D +    S    PAF+Q  +     V V  G K +L C+  + P  T+ W 
Sbjct: 1817 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1876

Query: 1133 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
             +G+ L   +     + G    + I++A   D+GLY C   N AG+A  +  +TV   P 
Sbjct: 1877 KDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPT 1934

Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
             EN K                  TE+ + V                            AG
Sbjct: 1935 FENPK------------------TETVSQV----------------------------AG 1948

Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
              + L   V+G    T TW+K R  ++ S    V +   G +L +   +    G YT + 
Sbjct: 1949 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVA 2006

Query: 1313 ENKLGSRQAQVNLTVVDKP 1331
            EN     +    + V+  P
Sbjct: 2007 ENTQAEARKDFVVAVLVAP 2025



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 40/138 (28%), Positives = 61/138 (44%), Gaps = 13/138 (9%)

Query: 626 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT----QHSLC 681
           ++GL D+ +  G +        G P P+V W    +    SE  H  Q G     + SL 
Sbjct: 7   IKGLGDVALTVGLEAG-GCGTHGTPKPQVTWRKGPS----SEPLH-GQPGVAVLEEGSLF 60

Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
           +  V P D+G Y C+A N  G    +A L V  P    +     +  +V+   GQS+ + 
Sbjct: 61  LASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIRED---GRKANVSGMAGQSLTLE 117

Query: 742 CAIAGDPFPTVHWLRDGK 759
           C   G P P + WL+D +
Sbjct: 118 CDANGFPVPEIVWLKDAQ 135



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 60/255 (23%), Positives = 92/255 (36%), Gaps = 54/255 (21%)

Query: 2   GDVKLVASSHISKTSLSVD-----PSRVDSMPLTEAPAFI-LPPRNLCIKEGATAKFEGR 55
           G  + VAS+    T L        P R+   P    P  +  P R  C   GA       
Sbjct: 761 GSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA------- 813

Query: 56  VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
               P P + W ++G P++  G   L     G   L + +    D G+Y+C A +  G  
Sbjct: 814 ----PSPTLMWLKDGNPVSPAGTPGLQV-FPGGRVLTLASARASDSGRYSCVAVSAVGED 868

Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
           +  V L V                             PSI GE       +L   VV   
Sbjct: 869 RQDVVLQVH--------------------------MPPSILGE-------ELNVSVVANE 895

Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
            +    C+    P P ++W K   PL+P   V +S    +  L++   +  D G YTC  
Sbjct: 896 SVA-LECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEA 952

Query: 236 VNGSGKASMSAELSI 250
           +N +G++     L++
Sbjct: 953 LNQAGRSEKHYNLNV 967



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
            +  G+ T      + E+ +D   A L A     P ++   S   R+  V+EG   R DC+
Sbjct: 1997 AQAGTYTCVAENTQAEARKDFVVAVLVA-----PRIRS--SGVAREHHVLEGQEVRLDCE 2049

Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P+V W KD   + +     + +  DG  SL++  +   D   YTC A N  GE
Sbjct: 2050 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLRASDAGAYTCVAHNPAGE 2107



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            +AP F+ + QD+ V  G  + L+CQ + +P  TI W   G+ L+ ++ +    +GSL   
Sbjct: 3116 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLE 3175

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
            ++E     D G Y CVA N  G A     + V   P
Sbjct: 3176 NVETG---DAGTYDCVAHNLLGSATARAFLVVRGEP 3208



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 62/282 (21%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L  V    G+ L L CQ S  P  TI W  NG+  +    + ++ +G+  ++ I+    +
Sbjct: 505  LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT--TLHIDHVELD 562

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD--------DAPASENTKAPEMKSRRPKSSLPP--- 1212
              GL+ C A N+AG A    +V+V         + P  +     E  S  P +  PP   
Sbjct: 563  HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 622

Query: 1213 ----------VLGTESDATVKKKP-----APKTPP------------------------- 1232
                      V G  S  ++  +P     A   PP                         
Sbjct: 623  GWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE 682

Query: 1233 -------KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                   K  +PP I   P ++ V    SV L    +G  P   +W K  + +  S  M 
Sbjct: 683  SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMG 740

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            V  S +G  L I  A+    G Y  +  N  GS + +  L V
Sbjct: 741  VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 782



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 53/285 (18%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            V V +     L+C  +  PP T+ W  +G+ +     + L  +G   S+ +E+A     G
Sbjct: 1077 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTG 1134

Query: 1167 LYKCVAKNDAGQAECSCQVTV--------DDAPASENTKA----------------PEMK 1202
             Y CVA+N AG+AE   +++V        D  P +  T A                P ++
Sbjct: 1135 RYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1194

Query: 1203 SRRPKSSLPPVLGT---------------ESDATVKKKPAPKTPPKA--------AMPPQ 1239
              R +  + P   T               E D+ +    A     +A         +PP 
Sbjct: 1195 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1254

Query: 1240 I--IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
            I      E  KV  G++  L   VTG      TW K  + +   +   +  S +G  L +
Sbjct: 1255 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHI--SPDGVLLQV 1312

Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
            L A     G Y+ +  N +G +     L+V+  P    G   ++D
Sbjct: 1313 LQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1357



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P     + DL   EGS A   CK  G P+P + W KD Q +  +   +  +    +  
Sbjct: 2845 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA---EGKFTIQPSGE 2901

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            L++ ++ G D   YTC A N++G A     L +
Sbjct: 2902 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2934



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 41/233 (17%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            +++V       L L+C+  + PP TI W  +G+ +  +  + +  EG L  + I+     
Sbjct: 1455 VKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVS 1512

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP----ASENTKAPEMKSRRPKSSLPPVLGTESD 1219
            D G Y CVA N AG+ +    V +   P      + + A E+ SR  ++       TE  
Sbjct: 1513 DSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV---TEYR 1569

Query: 1220 ATVKKKPA-PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
              V+  PA       A  PP +  + EDQ + AG+ V +                     
Sbjct: 1570 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVL-------------------- 1609

Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
                       + G  L I   R E+ G Y+    N++G       L V+  P
Sbjct: 1610 -----------QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP 1651



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 56/256 (21%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            + V +G+   L C V+  P   + W  +G+ L       +S +G L  V   +A     G
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL--QANLSSAG 1321

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
             Y C+A N  G+     Q++V  AP                     +LG   D+      
Sbjct: 1322 HYSCIAANAVGEKTKHFQLSVLLAPT--------------------ILGGAEDSA----- 1356

Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                              E+  V     + L  +         TWMK     + S ++++
Sbjct: 1357 -----------------DEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL 1399

Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----DPPAGTPCASD 1342
                +G  L IL A++E  G YT +V N+LG      ++ V+  P    D P G     +
Sbjct: 1400 LPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKE 1457

Query: 1343 IR---SSSLTL---SW 1352
            ++   +S+LTL   SW
Sbjct: 1458 VKTKVNSTLTLECESW 1473



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 43/208 (20%), Positives = 71/208 (34%), Gaps = 40/208 (19%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
            +   +T   +    G P P ++W +NG P +   R  +   +     L +      D   
Sbjct: 1666 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV---LEDGQVLQVSTAEVADAAS 1722

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y C A N +G+ +    L V                                  + PP+ 
Sbjct: 1723 YMCVAENQAGSAEKLFTLRV----------------------------------QVPPRI 1748

Query: 164  A-TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
            A   L +V           C +   P P+VTW K +  L     V +    G   L++  
Sbjct: 1749 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLP--GTHTLQLGR 1806

Query: 223  VNQDDVGVYTCLVVNGSGKASMSAELSI 250
                D G+YTC  +N +G+     +LS+
Sbjct: 1807 ARLSDSGMYTCEALNAAGRDQKLVQLSV 1834



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 52/234 (22%), Positives = 83/234 (35%), Gaps = 69/234 (29%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G  + L C V  DP   I W  +G  L+ +      Q GSL   +I +   +D G Y+C+
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSL---TIHRTERDDAGRYQCL 3098

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A+N+ G A+    + +  AP  +                                     
Sbjct: 3099 AENEMGVAKKVVILVLQSAPVFQVE----------------------------------- 3123

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK------ 1285
                        P+D  VR+G+ V L  + TG    T  W++  + ++ S  ++      
Sbjct: 3124 ------------PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS 3171

Query: 1286 --VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
              +EN E G             G Y  +  N LGS  A+  L V  +P    G+
Sbjct: 3172 LWLENVETGD-----------AGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS 3214



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 48/219 (21%)

Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
            V E   + L+C  S  PP  + W    + + +   + +S +G +  + IE+A   D G Y
Sbjct: 706  VLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSY 763

Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
            +CVA N AG  E    + V+                                        
Sbjct: 764  RCVASNVAGSTELRYGLRVN---------------------------------------- 783

Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              PP+  +PP +        V     V L    TG    T  W+K    +  +    ++ 
Sbjct: 784  -VPPRITLPPSL-----PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 837

Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               G  LT+ +AR    G Y+ +  + +G  +  V L V
Sbjct: 838  FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 49/220 (22%), Positives = 83/220 (37%), Gaps = 53/220 (24%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G+ + + C V   PP  + W  +G  L  ++  +L   GS  ++ I K    D G++ CV
Sbjct: 2137 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--HGSGHTLRISKVQLADAGIFTCV 2194

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A + AG A+ +  + V                      +PPVL                 
Sbjct: 2195 AASPAGVADRNFTLQV---------------------QVPPVL----------------- 2216

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                   + ++F  D  V  G  VEL  +  G      +WMK      + E +  ++ E 
Sbjct: 2217 -------EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK------DGEPLLSQSLEQ 2263

Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            G  L + A      G Y+ +  ++ G  +    LTV++ P
Sbjct: 2264 GPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPP 2303



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 21/228 (9%)

Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAE---------TLKPMGNAKPDEN 1058
            V    P +   P GP   VG A     L+    A+PA           L+   + +  E 
Sbjct: 2383 VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER 2442

Query: 1059 LKSASKEELKKDVKNDVNCK-RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLL 1117
             +    + L      D +C  R  AG+T    R E   T P  +     V+V+  +  LL
Sbjct: 2443 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-TVPTIRSGPPAVNVSVNQTALL 2501

Query: 1118 QCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
             CQ    P   + W  +   L  ++ +F IL  EGSL    I+  L +D G Y C+A N 
Sbjct: 2502 PCQADGVPAPLVSWRKDRVPLDPRSPRFEILP-EGSL---RIQPVLAQDAGHYLCLASNS 2557

Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            AG       + V + PA     AP   +    +  P +L  E+  + K
Sbjct: 2558 AGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGSPK 2601



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F    +D+ V  G      C+  G P P + W +  Q +R SR  +   D     SL 
Sbjct: 3118 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----SLW 3173

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 1854
            + +V   D   Y C A N LG AT  A L+V    +G
Sbjct: 3174 LENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG 3210



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
            E+VE + A   C     P P++ W+++DQ +       +     G   L I  V  ++  
Sbjct: 1570 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV---LQGGRVLQIPLVRAENAG 1626

Query: 1828 KYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
            +Y+CKA N +GE     EL+V T     G+ EE
Sbjct: 1627 RYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 1659



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 60/271 (22%), Positives = 108/271 (39%), Gaps = 53/271 (19%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V E   + L C+    P   I W  +G  L T+  ++ ++ G    + + +A   D 
Sbjct: 320  EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDA 377

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENT--------------KAPEMKSR-RPKSSL 1210
            G+Y C A N  G AE + ++ V   P  E                 A E  +R  P  +L
Sbjct: 378  GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL 437

Query: 1211 P------PVLGT-----ESDATVKKKPAP------------KTPPKAA---------MPP 1238
                   PV  +     E+D +V +  +P             +P   A         +PP
Sbjct: 438  SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 497

Query: 1239 QIIQFPEDQKVR--AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
            Q++      +V    G+ +EL  + +G+   T  W++  +  +E   ++V  +  G+ L 
Sbjct: 498  QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQV--ASQGTTLH 555

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            I     +H G +     N+ G+  A+V ++V
Sbjct: 556  IDHVELDHSGLFACQATNEAGTAGAEVEVSV 586



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            DV V  G  + L C+    P   + W  +G+ L +       ++G   S+ +E     D 
Sbjct: 2224 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL----EQGP--SLQLEAVGAGDS 2277

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
            G Y CVA ++AG+A    Q+TV + P  E++  P   S  P
Sbjct: 2278 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTP 2318



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            ++ V+E    +  C+  G P P + WFKD   +  S   ++ Y   G   L +      D
Sbjct: 320  EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST--KVVYTRGGR-QLQLGRAQSSD 376

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
               YTCKA N++G A     L V      EG G
Sbjct: 377  AGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 409



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 2/86 (2%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V   + + L+CQ  + PP  + W  +G+ L+    + LS + +L  + +++A   D 
Sbjct: 888  NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDA 945

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP 1191
            G Y C A N AG++E    + V  AP
Sbjct: 946  GHYTCEALNQAGRSEKHYNLNVWVAP 971



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            ++V++G  A   C + G+P P++ WFKD + +       I  D      L +        
Sbjct: 1264 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQANLSSA 1320

Query: 1827 AKYTCKAVNSLGEAT---CTAELIVETMEEGEGEGEEEE 1862
              Y+C A N++GE T     + L+  T+  G  +  +EE
Sbjct: 1321 GHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 1359



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
            ++ +++V V     + LQC    +P  TI W  NG     +  + + ++G +  VS  + 
Sbjct: 1658 EELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1717

Query: 1161 LPEDRGLYKCVAKNDAGQAE 1180
               D   Y CVA+N AG AE
Sbjct: 1718 --ADAASYMCVAENQAGSAE 1735



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 7/97 (7%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            D+ VV GS     C+  G P P V W KD + +       +    +   SL +  V   D
Sbjct: 2224 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL-------LSQSLEQGPSLQLEAVGAGD 2276

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
               Y+C AV+  GEA    +L V      E  G+  E
Sbjct: 2277 SGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTE 2313



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 77/363 (21%), Positives = 129/363 (35%), Gaps = 71/363 (19%)

Query: 987  GKKKLPAENGSSSAETLNA-----KAVESS---KPLSNAQPSGPLKPV-GNAKPAETLKP 1037
            G+ +L +++G  + E LNA     K V+ S    P     P GP   V         L  
Sbjct: 1805 GRARL-SDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 1863

Query: 1038 MGNAKPAETL------KPMGNAKPDENLKSASKEELKKDVKND---VNCKRGHAGTTDNE 1088
              +A P  T+      +P+  A+  + L+   + E+++   +D    +CK  +       
Sbjct: 1864 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR 1923

Query: 1089 KRSESQGTAPAFKQ-KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI-IL 1146
              + +    P F+  K + V    G  L+L C VS  P  T+ W  +   ++++    ++
Sbjct: 1924 TFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV 1983

Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
            S+ G L    + +  P   G Y CVA+N   +A     V V  AP             R 
Sbjct: 1984 SRGGRL---QLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP-------------RI 2027

Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
            +SS                                    +  V  G+ V L  +  G  P
Sbjct: 2028 RSS--------------------------------GVAREHHVLEGQEVRLDCEADGQPP 2055

Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVN 1324
                W+K    + +     +    +G  L +   R    G YT +  N  G  +R   VN
Sbjct: 2056 PDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVN 2115

Query: 1325 LTV 1327
            + V
Sbjct: 2116 VLV 2118



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES--RHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            G + + DC + G P P++ W KD   +R S  RH      +  N SL I     DD  +Y
Sbjct: 3042 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH------QLQNGSLTIHRTERDDAGRY 3095

Query: 1830 TCKAVNSLGEATCTAELIVET 1850
             C A N +G A     L++++
Sbjct: 3096 QCLAENEMGVAKKVVILVLQS 3116



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+   +P P + W KD      SR+ Q+     G   L I +   +D  +YTC   N LG
Sbjct: 1372 CEALAFPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELG 1428

Query: 1839 EA 1840
            EA
Sbjct: 1429 EA 1430



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            G  A   C+ +  P+P V W+KD Q +  ++  Q      G   L I +    D   Y+C
Sbjct: 1856 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA---LRGGQRLEIQEAQVSDKGLYSC 1912

Query: 1832 KAVNSLGEATCTAELIVE 1849
            K  N  GEA  T  L V+
Sbjct: 1913 KVSNVAGEAVRTFTLTVQ 1930



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)

Query: 1766 DLEVVEG---SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
            DLE V     S+    C +  +P+PEV W+KD Q++         +   G  +L +    
Sbjct: 1752 DLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGTHTLQLGRAR 1808

Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   YTC+A+N+ G      +L V
Sbjct: 1809 LSDSGMYTCEALNAAGRDQKLVQLSV 1834



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 53/243 (21%)

Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
            +  E++G    +++      + E     L C  ++ PP  + W    + L     + + Q
Sbjct: 1557 REEEARGGVTEYRE------IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1610

Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
             G +  + + +A  E+ G Y C A N+ G+     ++ V                     
Sbjct: 1611 GGRVLQIPLVRA--ENAGRYSCKASNEVGEDWLHYELLV--------------------- 1647

Query: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268
              PPV+  +++  V                      E+  V A  +V L     G    T
Sbjct: 1648 LTPPVILGDTEELV----------------------EEVTVNASSTVSLQCPALGNPVPT 1685

Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
             +W++       S  ++V   E+G  L +  A       Y  + EN+ GS +    L V 
Sbjct: 1686 ISWLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 1743

Query: 1329 DKP 1331
              P
Sbjct: 1744 VPP 1746



 Score = 40.0 bits (92), Expect = 0.021
 Identities = 26/71 (36%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 182 CKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
           C   G P+PQVTW KG  + PL     V+V E+     L +  V+  D G Y C   N  
Sbjct: 24  CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS---LFLASVSPADSGDYECQATNEV 80

Query: 240 GKASMSAELSI 250
           G  S  A+L +
Sbjct: 81  GSTSRRAKLVV 91



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
            C   ++  +D + R       PA      ++ +      LL C+ S  P   ++W  +G+
Sbjct: 2552 CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQ 2611

Query: 1137 TLKTTKFIILSQEGSLCSVSIEKAL-----PEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
             L         Q+G+   +     L     P+D   ++CV  N+ G+A    QVTV   P
Sbjct: 2612 KLD-----FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPP 2666



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/278 (23%), Positives = 93/278 (33%), Gaps = 49/278 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVS 1156
            P       D  V     ++L C  +  P  T+ W+  G  L        +S  G+L    
Sbjct: 2666 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL---E 2722

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP------------ASENTKAPEMKSR 1204
            I +ALP   G Y C A+N AG A     +TV  +P            A E    P   S 
Sbjct: 2723 IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG 2782

Query: 1205 RP-------KSSLPPVLGTESDA--------------------TVKKKPA----PKTPPK 1233
             P       K  L    G  +                       + K  A     KT   
Sbjct: 2783 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLV 2842

Query: 1234 AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
              +PP I     D     G    L  K  G+     TW K  + +  +E  K     +G 
Sbjct: 2843 VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEG-KFTIQPSG- 2900

Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +L +     +  G YT   EN +G  + +V+LT++  P
Sbjct: 2901 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 2938



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 15/157 (9%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            ++V V     + L C+  + P   I W  +G   + ++ I L        + I  A  ED
Sbjct: 1358 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKED 1415

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA-SENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             G Y CV  N+ G+A  +  V V   P+ S++    E+  +  K+ +   L  E ++   
Sbjct: 1416 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESW-- 1473

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
                      A  PP I  + + Q V     +++ G+
Sbjct: 1474 ----------AVPPPTIRWYKDGQPVTPSSRLQVLGE 1500



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 6/72 (8%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQ--IDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1836
            C   G P P+V W K   S  E  H Q  +   E+G  SL ++ V   D   Y C+A N 
Sbjct: 24   CGTHGTPKPQVTWRKGPSS--EPLHGQPGVAVLEEG--SLFLASVSPADSGDYECQATNE 79

Query: 1837 LGEATCTAELIV 1848
            +G  +  A+L+V
Sbjct: 80   VGSTSRRAKLVV 91



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 45/250 (18%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            GD    A +    TS++    RV+   +   P     P  + +    TA    +  G P 
Sbjct: 2457 GDYSCTARNAAGSTSVAF---RVE---IHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA 2510

Query: 62   PQVTWHRNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            P V+W ++  P+     RF     I    SL I  V  +D G Y C A+N +G+ +   +
Sbjct: 2511 PLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 2566

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            L V                       PA+   PS               + +        
Sbjct: 2567 LRV--------------------LEPPAIAPSPS--------------NLTLTAHTPALL 2592

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             C+ +G P+P V W K    L    +           L +      D   + C+V N  G
Sbjct: 2593 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 2652

Query: 241  KASMSAELSI 250
            +A    ++++
Sbjct: 2653 EAHRLYQVTV 2662



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P  + +  +L +   + A   C+  G P P VVW+KD Q + + R  Q  Y    + +L+
Sbjct: 2573 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL-DFRLQQGAYRLLPSNALL 2631

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEA 1840
            ++     D A++ C   N +GEA
Sbjct: 2632 LTAPGPQDSAQFECVVSNEVGEA 2654



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 13/132 (9%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F     D  +  G +L L+C     P   I WT+N + +       +S++    ++  
Sbjct: 2938 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 2993

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT- 1216
                 ED G Y C A+N  G+ +    V V +AP  +      +        + PV G+ 
Sbjct: 2994 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYL--------VEPVGGSI 3045

Query: 1217 ESDATVKKKPAP 1228
            + D  V+  P P
Sbjct: 3046 QLDCVVRGDPVP 3057



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 37/146 (25%), Positives = 54/146 (36%), Gaps = 48/146 (32%)

Query: 58  GYPEPQVTWHR-------NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
           G P+PQVTW +       +GQP    G  +L+ G     SL + +V   D G Y C+ATN
Sbjct: 28  GTPKPQVTWRKGPSSEPLHGQP----GVAVLEEG-----SLFLASVSPADSGDYECQATN 78

Query: 111 GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
             G+     +L V                    +  P++            +   +   V
Sbjct: 79  EVGSTSRRAKLVV--------------------YVPPSI------------REDGRKANV 106

Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLK 196
               GQ     C   G P P++ WLK
Sbjct: 107 SGMAGQSLTLECDANGFPVPEIVWLK 132



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 8/149 (5%)

Query: 1694 WQKTG---NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
            W K G    A R I  L     +  L+ +K   G  T  +  E  E+ ++     L   +
Sbjct: 1384 WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 1443

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
              K    P     +++++    S    +C+    P P + W+KD Q +  S   Q+  + 
Sbjct: 1444 ISKDD--PLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE- 1500

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
                 L I      D  +Y C A N  GE
Sbjct: 1501 --GRLLQIQPTQVSDSGRYLCVATNVAGE 1527



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 8/105 (7%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K G        L S ++  G S +  + G+  S   +    SE   ++   +    E 
Sbjct: 2249 WMKDGEP------LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 2302

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1798
            PH++     T  +L +  G+     C  +G P P + W KD Q++
Sbjct: 2303 PHIEDSGQPT--ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL 2345



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 4/92 (4%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            G+     C   G P P+V W KD Q +     H Q+   EDG    I     G D+ +Y 
Sbjct: 232  GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV--QEDGQVLRITGSHVG-DEGRYQ 288

Query: 1831 CKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
            C A +  G+     +L V       G  E  E
Sbjct: 289  CVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 320



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            + VV+   A  +C   G P P V W +D Q +      Q+   ++   SL +        
Sbjct: 1077 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQL---QNQGQSLHVERAQAAHT 1133

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
             +Y+C A N  G A    EL V
Sbjct: 1134 GRYSCVAENLAGRAERKFELSV 1155



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1778 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1837
            +C +E  P P++ W +D   ++E  H Q  + E G   L +  +   D   Y+C A N+ 
Sbjct: 2411 ECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGR-FLQLQALSTADSGDYSCTARNAA 2467

Query: 1838 GEATCTAELIVETM 1851
            G  +    + + T+
Sbjct: 2468 GSTSVAFRVEIHTV 2481



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P F+    D  +  G      C   G P P + W  +D+ + E        ++DG  +
Sbjct: 2936 VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGST 2990

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
            L  + V  +D   Y C A N +G     + + V+     +GE
Sbjct: 2991 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 3032



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+  +  R  C   G P P ++W KD   +  +    +     G   L ++     D  +
Sbjct: 798  VLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-LTLASARASDSGR 856

Query: 1829 YTCKAVNSLGE 1839
            Y+C AV+++GE
Sbjct: 857  YSCVAVSAVGE 867



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 19/153 (12%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K GN V            +G  G +   G     L + +       S   + AV E++
Sbjct: 820  WLKDGNPVSP----------AGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 869

Query: 1754 P------HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
                   H+ P       ++ VV   +   +C+    P P + W+KD + +       + 
Sbjct: 870  QDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS 929

Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
             D+     L +      D   YTC+A+N  G +
Sbjct: 930  ADK---ALLQVDRADVWDAGHYTCEALNQAGRS 959



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 1236 MPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
            +PPQI    + P    V       L    TG  P T TW +  + +     ++++N   G
Sbjct: 1063 VPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQ--G 1120

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
              L +  A+  H G Y+ + EN  G  + +  L+V+  P+
Sbjct: 1121 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPE 1160



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 15/124 (12%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            ++ +  G  + L C     P   I W  +G+ L  T+    S+   +  V        D 
Sbjct: 2313 ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--TRLENNSRATRVLRV-------RDA 2363

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            GLY C+A++ AG  E S +V V   P     + P          L  VL    + +V+ +
Sbjct: 2364 GLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL--VL----ECSVEAE 2417

Query: 1226 PAPK 1229
            PAPK
Sbjct: 2418 PAPK 2421



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+E ++   +C   G P P+V WFK  Q +  S    +    DG   L I      D   
Sbjct: 706  VLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRV-LRIEQAQLSDAGS 762

Query: 1829 YTCKAVNSLG 1838
            Y C A N  G
Sbjct: 763  YRCVASNVAG 772



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 59/265 (22%), Positives = 90/265 (33%), Gaps = 65/265 (24%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPE 1163
            Q+V    G  + LQC  S  P   + WT + +  L     + + ++G +  ++       
Sbjct: 225  QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--G 282

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y+CVA + AGQ     Q+ V  AP                   P + G+     V 
Sbjct: 283  DEGRYQCVAFSPAGQQARDFQLRV-HAP-------------------PTIWGSNETGEV- 321

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                      A M   ++Q              L  +  G      TW K    +  S  
Sbjct: 322  ----------AVMEDHLVQ--------------LLCEARGVPTPNITWFKDGALLPTS-- 355

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------------ 1331
             KV  +  G +L +  A+    G YT    N +G+ +    L V   P            
Sbjct: 356  TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV 415

Query: 1332 DPPAGTPCASDIRS---SSLTLSWY 1353
               AG P A +  +    S TLSW+
Sbjct: 416  KAVAGRPVALECVARGHPSPTLSWH 440



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+  G P P + WF+ ++ +      +  Y   G   L ++     D   Y+C A N  G
Sbjct: 1183 CEAMGIPPPAIRWFRGEEPVSPG---EDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1239

Query: 1839 EATCTAELIVETMEEGEGEGEEEEE 1863
            EA       VE +     E E+ EE
Sbjct: 1240 EA--RRNFSVEVLVPPSIENEDLEE 1262



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 11/27 (40%), Positives = 16/27 (59%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSI 1798
            G +   +C   G+P PE+VW KD Q +
Sbjct: 111  GQSLTLECDANGFPVPEIVWLKDAQLV 137



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            H  P        + V     A   C+ +G P P V W KD   + + R  + +   +G  
Sbjct: 2479 HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL-DPRSPRFEILPEG-- 2535

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
            SL I  V   D   Y C A NS G
Sbjct: 2536 SLRIQPVLAQDAGHYLCLASNSAG 2559



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 12/101 (11%)

Query: 1751 EEKPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY 1808
            +  P VKP  S  + + + EV+        C+  G P P + W K+  ++      Q+  
Sbjct: 2754 QASPVVKPLPSVVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVL- 2806

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                   L I+    +D   Y C A NS G A     L+V+
Sbjct: 2807 ---PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2844



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%)

Query: 1719 RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 1778
            R  S G  +S L +    +     +A L+   E +   +   ++ +  +  + G      
Sbjct: 462  RLESPGEASSGLYS--CVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELP 519

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+  G P P + W ++ +   E    Q+        +L I  V  D    + C+A N  G
Sbjct: 520  CQASGSPVPTIQWLQNGRPAEELAGVQV---ASQGTTLHIDHVELDHSGLFACQATNEAG 576

Query: 1839 EATCTAELIV 1848
             A    E+ V
Sbjct: 577  TAGAEVEVSV 586



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 3/71 (4%)

Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            V GS     C + G P P V W KD   +  S    +     G   L +S +       Y
Sbjct: 1946 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTY 2002

Query: 1830 TCKAVNSLGEA 1840
            TC A N+  EA
Sbjct: 2003 TCVAENTQAEA 2013



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-D 1825
            ++ V G     +C   G+P P + W  +   + ES   +++ D     S++  +  G+  
Sbjct: 415  VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG----SVLRLESPGEAS 470

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEE---GEGEGE 1859
               Y+C A +  GEA     + V+   +    EG G+
Sbjct: 471  SGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ 507



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 1/93 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            L V EG      C+  G P P++ W KD Q +       + +       L +       +
Sbjct: 981  LTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQE 1039

Query: 1827 AKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
              YTC+  N +G ++   +L V    +  G  E
Sbjct: 1040 GTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 1072


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score =  171 bits (434), Expect = 5e-42
 Identities = 181/790 (22%), Positives = 294/790 (37%), Gaps = 114/790 (14%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P  L +  GA  +     +G P+P +TWH++GQ +T      L+   R T  L +     
Sbjct: 3502 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR-----LENNSRATRVLRVR---- 3552

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
             D G YTC A + +GA                     + K+   R  AP     P+I G 
Sbjct: 3553 -DAGLYTCLAESPAGA---------------------IEKSFRVRVQAP-----PNIVGP 3585

Query: 159  CPPKFATKL--GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
              P+F   L  G++V++        C +   P P++TW +  + LQ  A     E+   +
Sbjct: 3586 RGPRFVVGLAPGQLVLE--------CSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--R 3635

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-----------SANRSFVRETK 265
             L++  ++  D G Y+C   N +G  S++  + I  +            S N++ +   +
Sbjct: 3636 FLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQ 3695

Query: 266  ATNSDV-----RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
            A          RK+   +  +  + + L   +        Q  G     A++     R+ 
Sbjct: 3696 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQG 3755

Query: 321  KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR--------APGLGVLSPSGEERK 372
            +     + P  AP    L  T+ +  L        P+           L      G  R 
Sbjct: 3756 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 3815

Query: 373  RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
             P+     T P  Q     + VVS        +        P          V     V 
Sbjct: 3816 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVV 3875

Query: 433  FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
              C  +GIP P V+W   G  +  +      Y  + S  L + +A    +G Y+C+A N+
Sbjct: 3876 LTCHSTGIPAPTVSWSKAGAQLGARGSG---YRVSPSGALEIGQALPIHAGRYTCSARNS 3932

Query: 493  QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
             G       L V+   V++  PS    + +      ++ +L C   G P P ITW   G 
Sbjct: 3933 AGVAHKHVFLTVQASPVVKPLPSVVRAVAE------EEVLLPCEASGIPRPTITWQKEGL 3986

Query: 553  PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 612
             +    ST      +L I  A PED G Y C+A+N+ G       + V            
Sbjct: 3987 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ----------- 4035

Query: 613  LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHF 671
                      P+   GL DL   +GS   +  +  G+P P + W  +G  +  +E  F  
Sbjct: 4036 --------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI 4087

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 731
            +  G    L ++ +  +D GTYTC A N+ G  R +  LT+        P F + P   +
Sbjct: 4088 QPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRS 4139

Query: 732  ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791
              LG  + + CA  G P P + W  + + + +      V + +   TL    V    +G 
Sbjct: 4140 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSEQDGGSTLQRAAVSREDSGT 4194

Query: 792  YEILLKNRVG 801
            Y    +NRVG
Sbjct: 4195 YVCWAENRVG 4204



 Score =  169 bits (429), Expect = 2e-41
 Identities = 197/775 (25%), Positives = 290/775 (37%), Gaps = 145/775 (18%)

Query: 45   KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
            K  +T   E      P P + W+++GQP+T   R  +   +     L I      D G+Y
Sbjct: 2652 KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQV---LGEGRLLQIQPTQVSDSGRY 2708

Query: 105  TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
             C ATN +G       + ++         P + + +GD  +A  + +R     E      
Sbjct: 2709 LCVATNVAGEDDQDFNVLIQ--------VPPMFQKVGDFSAAFEILSRE----EEARGGV 2756

Query: 165  TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
            T+   +V  E       C     P P +TW + + PL     VSV +  G +VL+I  V 
Sbjct: 2757 TEYREIV--ENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ--GGRVLQIPLVR 2812

Query: 225  QDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESK 284
             ++ G Y+C   N  G+  +  EL            V        D  + V  V    S 
Sbjct: 2813 AENAGRYSCKASNEVGEDWLHYEL-----------LVLTPPVILGDTEELVEEVTVNASS 2861

Query: 285  LDSLEAAAKSKNCSSPQRGGSPP---WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
              SL+          P  G   P   W  N  P  P                 +P LQ  
Sbjct: 2862 TVSLQC---------PALGNPVPTISWLQNGLPFSP-----------------SPRLQVL 2895

Query: 342  SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANR 401
                 LQ +  +    A  + V        ++    R    P R  GL  + V +     
Sbjct: 2896 EDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLR-VQVPPRIAGLDLEQVTAIL--- 2951

Query: 402  RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSI 461
                                      N +V   C+V   P PEV W+ +   +   E   
Sbjct: 2952 --------------------------NSSVSLPCDVHAHPNPEVTWYKDSQALSLGE--- 2982

Query: 462  EVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLK 521
            EV+   G+H L L +AR  DSG Y+C A NA G+       ++ +L+V+ V P+F    +
Sbjct: 2983 EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR-----DQKLVQLSVL-VPPAFRQAPR 3036

Query: 522  ---DCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPE 576
               D  ++  G   VL C     P P +TW  +GQP+  A R+    G   L IQ+A   
Sbjct: 3037 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS 3096

Query: 577  DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
            D G Y+C   N  G+   +  +TV            +P     P      Q       + 
Sbjct: 3097 DKGLYSCKVSNVAGEAVRTFTLTVQ-----------VPPTFENPKTETVSQ-------VA 3138

Query: 637  GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 696
            GS + +T  VSG P P V WL +   ++ S       RG +  L +  + P   GTYTC 
Sbjct: 3139 GSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGR--LQLSRLQPAQAGTYTCV 3196

Query: 697  AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL--------GQSVLISCAIAGDP 748
            A N+  E R   V+ V           +  PR  ++ +        GQ V + C   G P
Sbjct: 3197 AENTQAEARKDFVVAV-----------LVAPRIRSSGVAREHHVLEGQEVRLDCEADGQP 3245

Query: 749  FPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
             P V WL+DG  L +D G H       D  +LVLK ++   AG Y  +  N  GE
Sbjct: 3246 PPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVLKGLRASDAGAYTCVAHNPAGE 3298



 Score =  148 bits (374), Expect = 4e-35
 Identities = 204/819 (24%), Positives = 292/819 (35%), Gaps = 167/819 (20%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            EAP   +   +    +G   K      GYP P ++W R  Q +    R  +D   +GT  
Sbjct: 606  EAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDA--QGT-- 661

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L+I  V  ED G Y+C+ATN  G  Q TV L                             
Sbjct: 662  LIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD------------------------- 696

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
                     PP  +     V+V  G+     C+ +G P P+V W +G + +  +   S S
Sbjct: 697  ---------PPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSS 747

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
             K     L I    + D G YTC  VN  G AS   +L++                  ++
Sbjct: 748  GK-----LRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQL------------TE 790

Query: 271  VRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR 330
            + ++VT  + + + L +  A  +     + +RG   P             +L + + S  
Sbjct: 791  LPRDVTVELGRSALL-ACRATGRPPPTVTWRRGDGQPLGL----------RLGAGRGSRS 839

Query: 331  TAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390
              P + VL   S         V PE +AP +                             
Sbjct: 840  RQPDSGVLFFES---------VAPEDQAPYV---------------------------CE 863

Query: 391  SQDVVSKA-ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEV-SGIPKPEVAWF 448
            +++V  K  A  R+ + G    A P+  S   +  V E Q V   C V +G P PE  W 
Sbjct: 864  ARNVFGKVQAEARLIVTGH---APPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWL 920

Query: 449  LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLA 508
             +G P+    GS       GS  L L +A    +G YSC A+N  G    S    VE   
Sbjct: 921  KDGRPL--PPGSRHSIRADGS--LHLDRALQEHAGRYSCVATNTAG----SQHRDVE--L 970

Query: 509  VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV-AE 567
            V++V P            EG    L C   G P P ITW      +              
Sbjct: 971  VVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGT 1030

Query: 568  LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK--SEY-LLP---------- 614
            L I     +D G Y C A N +G  S    ++V+    S+    EY LLP          
Sbjct: 1031 LLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQ 1090

Query: 615  --------VAPSKPTA-------------PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                       S P               P    G   LKV+ G  + +     GNP P+
Sbjct: 1091 VGDSGHYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQ 1150

Query: 654  VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
            + W  +G  +Q         RG Q S+    +   D G Y CEA NSAG    +  L V 
Sbjct: 1151 LSWSKDGVVLQG--------RGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVL 1202

Query: 714  EPHDGTQPWFISKPRSVTASL-GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
            EP      W   +   +   + G++  + C   G P P V W R G +     G   V  
Sbjct: 1203 EP----PHWGADETSGLLERVAGENASLPCPARGTPKPQVTW-RKGPSSEPLHGQPGVAV 1257

Query: 773  NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 811
             E+  +L L  V P  +G YE    N VG  S +  L++
Sbjct: 1258 LEE-GSLFLASVSPADSGDYECQATNEVGSTSRRAKLVV 1295



 Score =  148 bits (373), Expect = 6e-35
 Identities = 110/380 (28%), Positives = 175/380 (46%), Gaps = 44/380 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C+  G P+P + W  +G PV   EG   +     S  L +     +D+GTY+CTA NA G
Sbjct: 4059 CKARGSPEPNITWDKDGQPVSGAEGKFTIQP---SGELLVKNLEGQDAGTYTCTAENAVG 4115

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
            +      L +       V P F+++  D ++  G    L+C+ RG+P PRI W +N +P+
Sbjct: 4116 RARRRVHLTIL------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV 4169

Query: 555  QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
                S  + G + L       ED GTY C AEN +G+    ++V V E            
Sbjct: 4170 TEGVSEQDGG-STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE------------ 4216

Query: 615  VAPSKPTAPIFLQG--LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
                   AP+ LQG   S L    G  + +   V G+P P++ W+ +G  ++ S   H  
Sbjct: 4217 -------APV-LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL 4268

Query: 673  QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 732
            Q G   SL I     +D G Y C A N  G  +   +L +Q     + P F  +P+ +T 
Sbjct: 4269 QNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-----SAPVFQVEPQDMTV 4320

Query: 733  SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
              G  V + C   G+P PT+ WL+ G+ L + +     L +    +L L+ V+   AG Y
Sbjct: 4321 RSGDDVALRCQATGEPTPTIEWLQAGQPL-RASRRLRTLPDG---SLWLENVETGDAGTY 4376

Query: 793  EILLKNRVGECSCQVSLMLQ 812
            + +  N +G  + +  L+++
Sbjct: 4377 DCVAHNLLGSATARAFLVVR 4396



 Score =  145 bits (366), Expect = 4e-34
 Identities = 120/405 (29%), Positives = 178/405 (43%), Gaps = 44/405 (10%)

Query: 412  AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            A P  +  P        + V   CE SGIP+P + W  EG  V     +    +      
Sbjct: 3946 ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST----QVLPGGQ 4001

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L +  A   D+G Y C A N+ G       L      V++V P   + L D +  EG   
Sbjct: 4002 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRL------VVQVPPVIENGLPDLSTTEGSHA 4055

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA-ELHIQDALPEDHGTYTCLAENALG 590
             L C  RG+P P ITW  +GQP+  A        + EL +++   +D GTYTC AENA+G
Sbjct: 4056 FLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 4115

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
            +      +T+           +LPV  + P          D  +  G ++ +     G+P
Sbjct: 4116 RARRRVHLTI----------LVLPVFTTLP---------GDRSLRLGDRLWLRCAARGSP 4156

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
             P + W  N   + E      EQ G   +L    V  ED+GTY C A N  G  RTQAV 
Sbjct: 4157 TPRIGWTVNDRPVTEGVS---EQDGGS-TLQRAAVSREDSGTYVCWAENRVG--RTQAVS 4210

Query: 711  TVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
             V   H    P    +  S +   +G S+ + C + GDP P +HW++DG  L + +    
Sbjct: 4211 FV---HVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-RGSHLRH 4266

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
             LQN    +L + + +   AG+Y+ L +N +G     V L+LQ++
Sbjct: 4267 QLQNG---SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 4308



 Score =  138 bits (347), Expect = 6e-32
 Identities = 185/745 (24%), Positives = 273/745 (36%), Gaps = 117/745 (15%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCG---IRG 87
            E PA    P NL +     A       G P+P V W ++GQ +     F L  G   +  
Sbjct: 3762 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD----FRLQQGAYRLLP 3817

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
            + +L++ A   +D  ++ C  +N  G      ++TV                        
Sbjct: 3818 SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----------------------- 3854

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                 P+I  +      T +  VV+        +C  TG P P V+W K    L   AR 
Sbjct: 3855 ---VPPTIADDQTDFTVTMMAPVVL--------TCHSTGIPAPTVSWSKAGAQL--GARG 3901

Query: 208  SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------LDSANRSFV 261
            S    +    LEI        G YTC   N +G A     L++Q       L S  R+  
Sbjct: 3902 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 3961

Query: 262  RETKATNSDV----------RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
             E      +           +KE  NV +  S         +  + S    G     A N
Sbjct: 3962 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 4021

Query: 312  SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA--ARVQPEPR------------ 357
            S      +++L   +  P      P L  T  S       AR  PEP             
Sbjct: 4022 SAGSAMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 4080

Query: 358  APGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFE 417
            A G   + PSGE   +    + A   T      +++ V +A  RR+ +        P F 
Sbjct: 4081 AEGKFTIQPSGELLVKNLEGQDAGTYT----CTAENAVGRA-RRRVHLT---ILVLPVFT 4132

Query: 418  SKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKA 477
            + P  + ++    +  RC   G P P + W +   PV   EG   V E  G   L     
Sbjct: 4133 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EG---VSEQDGGSTLQRAAV 4187

Query: 478  RTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
               DSGTY C A N  G+      + V+   V++   +FS +++      G    L C V
Sbjct: 4188 SREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ-GEAFSYLVEPV----GGSIQLDCVV 4242

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
            RG PVP I W+ +G P++ +    +     L I     +D G Y CLAEN +G       
Sbjct: 4243 RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVA----- 4297

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                      K   +L +     +AP+F     D+ V  G  V +  Q +G P P + WL
Sbjct: 4298 ----------KKVVILVL----QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 4343

Query: 658  HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPH 716
              G  ++ S        G   SL ++ V   D GTY C A N  G    +A L V+ EP 
Sbjct: 4344 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400

Query: 717  D--GTQPWFISKPRSVTASLGQSVL 739
               G+    I+  +   A+L  SV+
Sbjct: 4401 GSWGSMTGVINGRKFGVATLNTSVM 4425



 Score =  134 bits (336), Expect = 1e-30
 Identities = 186/829 (22%), Positives = 285/829 (34%), Gaps = 196/829 (23%)

Query: 58   GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
            G P P + W +NG+P        +    +GT +L I  V  +  G + C+ATN +G    
Sbjct: 1715 GSPVPTIQWLQNGRPAEELAG--VQVASQGT-TLHIDHVELDHSGLFACQATNEAGTAGA 1771

Query: 118  TVELTVEGSFAK-----QLGQ----------------PVVSKTLGDRFSAPAVE---TRP 153
             VE++V G +A       +GQ                P V +  G     P VE   +  
Sbjct: 1772 EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPG 1831

Query: 154  SIWGE-----------------------------------------------CPPKFATK 166
            S+WGE                                                PP     
Sbjct: 1832 SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPG 1891

Query: 167  LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
                 V E       C  +G P P V+W KG+ P+     V+VS     +VL I      
Sbjct: 1892 PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLS 1949

Query: 227  DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLD 286
            D G Y C+  N +G   +   L +                          NV  + +   
Sbjct: 1950 DAGSYRCVASNVAGSTELRYGLRV--------------------------NVPPRITLPP 1983

Query: 287  SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSS-- 344
            SL           P    +P     +    P  + +     +P +   TP LQ       
Sbjct: 1984 SL---------PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV 2034

Query: 345  ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG--LGSQDVVSKAANRR 402
            +TL +AR     R   + V S  GE+R      +        P   LG +  VS  AN  
Sbjct: 2035 LTLASARASDSGRYSCVAV-SAVGEDR------QDVVLQVHMPPSILGEELNVSVVANES 2087

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
            + +E Q  +                            +P P ++W+ +G P+  + G   
Sbjct: 2088 VALECQSHA----------------------------MPPPVLSWWKDGRPLEPRPG--- 2116

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V+  A    L + +A   D+G Y+C A N  G     + L V    V  +  S +  ++ 
Sbjct: 2117 VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVR- 2175

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHG 579
                EG    L C  RG P P+I+W  +GQP+    +  +   A    L++  A     G
Sbjct: 2176 ----EGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 2231

Query: 580  TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
            TYTC   N +G  S    + VH           +P   + P  P      + + V+    
Sbjct: 2232 TYTCECSNVVGNSSQDLQLEVH-----------VPPQIAGPREP-----PTQVSVVQDGV 2275

Query: 640  VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             T+    +G PPP V W  +G  +        + +G   SL ++      TG Y+C A N
Sbjct: 2276 ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG--QSLHVERAQAAHTGRYSCVAEN 2333

Query: 700  SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
             AG    +  L+V  P +      +    ++TA+L   + + C   G P P + W R   
Sbjct: 2334 LAGRAERKFELSVLVPPELIGD--LDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR--- 2388

Query: 760  ALCKDTGHFEVLQNEDVFTLV------LKKVQPWHAGQYEILLKNRVGE 802
                  G   V   ED + L       + + Q   +G Y  L  N  GE
Sbjct: 2389 ------GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 2431



 Score =  132 bits (331), Expect = 4e-30
 Identities = 130/463 (28%), Positives = 178/463 (38%), Gaps = 55/463 (11%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P+      SQ   +   VK  C  SG P P ++W  E   +  QE S  ++ DA    L 
Sbjct: 608  PQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQAL--QEDS-RIHVDA-QGTLI 663

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            +      D+G YSC A+N  G    + TL           PS S+V     V  G++ VL
Sbjct: 664  IQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD------PPSVSAVNAVVLVAVGEEAVL 717

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVS 593
             C   G P PR+ W   G  +  A     +G  +L I  A   D GTYTC A N LG  S
Sbjct: 718  VCEASGVPPPRVIWYRGGLEMILAPEGSSSG--KLRIPAAQERDAGTYTCRAVNELGDAS 775

Query: 594  CSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPE 653
                + V                     AP   +   D+ V  G    +  + +G PPP 
Sbjct: 776  AEIQLAVGH-------------------APQLTELPRDVTVELGRSALLACRATGRPPPT 816

Query: 654  VIWLH-NGNEIQESEDFHFEQRGTQHS---LCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            V W   +G  +          R  Q     L  + V PED   Y CEA N  G+V+ +A 
Sbjct: 817  VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEAR 876

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISC-AIAGDPFPTVHWLRDGKALCKDTGHF 768
            L V        P   S   +V    GQ V + C  +AG P P  HWL+DG+ L   + H 
Sbjct: 877  LIVT---GHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHS 933

Query: 769  EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASC 828
                     +L L +    HAG+Y  +  N  G     V L++Q      +P    P + 
Sbjct: 934  IRADG----SLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ------VPPRIHPTAT 983

Query: 829  EDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRG 871
              +   GV A          +  G PA    W +E +    RG
Sbjct: 984  HHITNEGVPAS------LPCVASGVPAPTITWTKETNALTSRG 1020



 Score =  128 bits (322), Expect = 5e-29
 Identities = 110/377 (29%), Positives = 156/377 (41%), Gaps = 44/377 (11%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V     V+  CE  G+P P V+W  +G P+  Q       E   S  L L      DSGT
Sbjct: 3418 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS-----LEQGPS--LQLEAVGAGDSGT 3470

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            YSC A +  G+    + L V     +E     S    + ++  G    L C  +GTP P 
Sbjct: 3471 YSCVAVSEAGEARRHFQLTVMEPPHIED----SGQPTELSLTPGAPMELLCDAQGTPQPN 3526

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
            ITW  +GQ +    +   A    L ++DA     G YTCLAE+  G +  S  V V    
Sbjct: 3527 ITWHKDGQALTRLENNSRA-TRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRVQA-- 3578

Query: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
                     P     P  P F+ GL+        Q+ +   V   P P++ W  +G  +Q
Sbjct: 3579 ---------PPNIVGPRGPRFVVGLAP------GQLVLECSVEAEPAPKITWHRDGIVLQ 3623

Query: 665  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
            E     F +RG    L +Q +   D+G Y+C A N+AG       + +      T P   
Sbjct: 3624 EDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-----TVPTIR 3676

Query: 725  SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784
            S P +V  S+ Q+ L+ C   G P P V W +D   L   +  FE+L      +L ++ V
Sbjct: 3677 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPV 3733

Query: 785  QPWHAGQYEILLKNRVG 801
                AG Y  L  N  G
Sbjct: 3734 LAQDAGHYLCLASNSAG 3750



 Score =  128 bits (321), Expect = 6e-29
 Identities = 116/443 (26%), Positives = 177/443 (39%), Gaps = 43/443 (9%)

Query: 431  VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
            V+ +C  SG+P P+V W  +  PV      ++V ED     L +  +   D G Y C A 
Sbjct: 1426 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG--QVLRITGSHVGDEGRYQCVAF 1483

Query: 491  NAQGQLSCSWTLQVERLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
            +  GQ +  + L+V         P+   S+   + AV+E     L C  RG P P ITW 
Sbjct: 1484 SPAGQQARDFQLRVH------APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 1537

Query: 549  LNGQPIQYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
             +G  +  +       G  +L +  A   D G YTC A NA+G            +K++R
Sbjct: 1538 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA----------EKATR 1587

Query: 608  KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
               Y+ P        P  +      K + G  V +     G+P P + W H G  + ES 
Sbjct: 1588 LDVYVPPTIEGAGGRPYVV------KAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN 1641

Query: 668  DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
            +   E  G+   L ++      +G Y+C A + AGE   Q  + VQ P    Q       
Sbjct: 1642 ESRLETDGSV--LRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVP---PQLLVAEGL 1696

Query: 728  RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
              VT  +GQ + + C  +G P PT+ WL++G+   +  G     Q     TL +  V+  
Sbjct: 1697 GQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT---TLHIDHVELD 1753

Query: 788  HAGQYEILLKNRVGECSCQVSLMLQNSSARA---LPRGREPASCEDLCGGGVGAD----- 839
            H+G +     N  G    +V + +    A     +P G+     E         D     
Sbjct: 1754 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 1813

Query: 840  GGGSDRYGSLRPGWPARGQGWLE 862
            G G+     L  GW + G  W E
Sbjct: 1814 GWGAHPKPPLVEGWCSPGSLWGE 1836



 Score =  126 bits (316), Expect = 2e-28
 Identities = 105/399 (26%), Positives = 166/399 (41%), Gaps = 47/399 (11%)

Query: 413  FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
            FP  ES   +  V+E       CE  G+P P+++W  +G P+  +   ++ +  A    L
Sbjct: 2164 FPLRES--HTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVSAVGRLL 2220

Query: 473  CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE---RLAVMEVAPSFSSVLKDCAVIEGQ 529
             L +A+    GTY+C  SN  G  S    L+V    ++A     P+  SV++D       
Sbjct: 2221 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVA---- 2276

Query: 530  DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV------AELHIQDALPEDHGTYTC 583
               L+C+  G P P +TW  +GQP+       E G+        LH++ A     G Y+C
Sbjct: 2277 --TLECNATGKPPPTVTWERDGQPV-----GAELGLQLQNQGQSLHVERAQAAHTGRYSC 2329

Query: 584  LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
            +AEN  G             ++ RK E  + V P        L  L+++     S +T+ 
Sbjct: 2330 VAENLAG-------------RAERKFELSVLVPPELIGD---LDPLTNITAALHSPLTLL 2373

Query: 644  VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             +  G PPP + W      +   ED +    G    L + +   +D+G Y+C A N AGE
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWM--LKMTQTQEQDSGLYSCLASNEAGE 2431

Query: 704  VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
             R    + V  P              +    GQ+  + C + G P P + W +DG+ L +
Sbjct: 2432 ARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLAR 2488

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
               H     + D   L + +     AG Y  +  N VGE
Sbjct: 2489 GDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGE 2524



 Score =  124 bits (311), Expect = 9e-28
 Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 53/433 (12%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P  E  P ++ V EN +V   C  SG+P P+V+WF    PV    G   V        L 
Sbjct: 1886 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTVSVDGRVLR 1942

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            + +A+  D+G+Y C ASN  G     + L+V     + + PS         V+      L
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPG-----PVLVNTPVRL 1997

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
             C+  G P P + WL +G P+  A +       G   L +  A   D G Y+C+A +A+G
Sbjct: 1998 TCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVG 2057

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
            +      + VH                     P  L    ++ V+    V +  Q    P
Sbjct: 2058 EDRQDVVLQVH-------------------MPPSILGEELNVSVVANESVALECQSHAMP 2098

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
            PP + W  +G  ++     H      +  L +      D G YTCEA N AG        
Sbjct: 2099 PPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGH------- 2149

Query: 711  TVQEPHDGTQPWF-----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
               E H     W      + +  ++T   G    +SC   G PFP + W +DG+ L    
Sbjct: 2150 --SEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL---P 2204

Query: 766  GHFEVLQNEDVF--TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR 823
            G    LQ+       L L + Q    G Y     N VG  S  + L +      A P  R
Sbjct: 2205 GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP--R 2262

Query: 824  EPASCEDLCGGGV 836
            EP +   +   GV
Sbjct: 2263 EPPTQVSVVQDGV 2275



 Score =  119 bits (298), Expect = 3e-26
 Identities = 109/396 (27%), Positives = 163/396 (41%), Gaps = 40/396 (10%)

Query: 423  QEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
            +E+ EN      C+ + IP P++ W+ E  P+   +   EV    G   L +   R  ++
Sbjct: 2760 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD---EVSVLQGGRVLQIPLVRAENA 2816

Query: 483  GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
            G YSC ASN  G+    + L V  L    +      ++++  V       LQC   G PV
Sbjct: 2817 GRYSCKASNEVGEDWLHYELLV--LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPV 2874

Query: 543  PRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            P I+WL NG P   +      E G   L +  A   D  +Y C+AEN  G          
Sbjct: 2875 PTISWLQNGLPFSPSPRLQVLEDGQV-LQVSTAEVADAASYMCVAENQAG---------- 2923

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                    +E L  +    P     L  L  +  +  S V++   V  +P PEV W  + 
Sbjct: 2924 -------SAEKLFTLRVQVPPRIAGLD-LEQVTAILNSSVSLPCDVHAHPNPEVTWYKDS 2975

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
              +   E+  F   GT H+L +      D+G YTCEA N+AG  +    L+V  P     
Sbjct: 2976 QALSLGEEV-FLLPGT-HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP----- 3028

Query: 721  PWFISKPR----SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
            P F   PR    +V   +G   ++SC     P PTV W +DG+ L       + L+    
Sbjct: 3029 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVL-AQRTQALRGGQ- 3086

Query: 777  FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              L +++ Q    G Y   + N  GE     +L +Q
Sbjct: 3087 -RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 3121



 Score =  119 bits (297), Expect = 4e-26
 Identities = 99/385 (25%), Positives = 157/385 (40%), Gaps = 45/385 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C V   P P++ W  +G  +  QE +   + + G  +L L    T DSG YSCTA NA G
Sbjct: 3603 CSVEAEPAPKITWHRDGIVL--QEDAHTQFPERG-RFLQLQALSTADSGDYSCTARNAAG 3659

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
              S ++ +++  +  +   P   +V  +      Q  +L C   G P P ++W  +  P+
Sbjct: 3660 STSVAFRVEIHTVPTIRSGPPAVNVSVN------QTALLPCQADGVPAPLVSWRKDRVPL 3713

Query: 555  QYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
                   E      L IQ  L +D G Y CLA N+ G              S R+   L 
Sbjct: 3714 DPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG--------------SDRQGRDLR 3759

Query: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
             + P     P      S+L +   +   +  + SG+P P V+W  +G ++    DF  +Q
Sbjct: 3760 VLEP-----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQ 3810

Query: 674  RGTQ----HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
               +    ++L +    P+D+  + C   N  GE      +TV  P     P        
Sbjct: 3811 GAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVP-----PTIADDQTD 3865

Query: 730  VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             T ++   V+++C   G P PTV W + G  L      + V  +     L + +  P HA
Sbjct: 3866 FTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHA 3922

Query: 790  GQYEILLKNRVGECSCQVSLMLQNS 814
            G+Y    +N  G     V L +Q S
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQAS 3947



 Score =  118 bits (296), Expect = 5e-26
 Identities = 106/390 (27%), Positives = 145/390 (37%), Gaps = 41/390 (10%)

Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
           V   +T    C V G     + W  +   +    G +    D       ++     D G 
Sbjct: 528 VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPT---DGGR 584

Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
           Y C ASNA G    S  L V        AP  S         +G +  + CS  G P P 
Sbjct: 585 YQCVASNANGVTRASVWLLVRE------APQVSIHTSSQHFSQGVEVKVSCSASGYPTPH 638

Query: 545 ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
           I+W    Q +Q            L IQ   PED G Y+C A N +G  +    VT++   
Sbjct: 639 ISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVG--TDQETVTLY--- 693

Query: 605 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
                 Y  P + S   A +         V  G +  +  + SG PPP VIW   G E+ 
Sbjct: 694 ------YTDPPSVSAVNAVVL--------VAVGEEAVLVCEASGVPPPRVIWYRGGLEMI 739

Query: 665 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
            + +       +   L I      D GTYTC A N  G+   +  L V     G  P   
Sbjct: 740 LAPE-----GSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV-----GHAPQLT 789

Query: 725 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLR-DGK--ALCKDTGHFEVLQNEDVFTLVL 781
             PR VT  LG+S L++C   G P PTV W R DG+   L    G     +  D   L  
Sbjct: 790 ELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFF 849

Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLML 811
           + V P     Y    +N  G+   +  L++
Sbjct: 850 ESVAPEDQAPYVCEARNVFGKVQAEARLIV 879



 Score =  118 bits (296), Expect = 5e-26
 Identities = 106/388 (27%), Positives = 155/388 (39%), Gaps = 48/388 (12%)

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            +P    +     ++  C+  G P+P + W  +G  + R E +                 R
Sbjct: 3501 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR----------VLR 3550

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
             RD+G Y+C A +  G +  S+ ++V+    + V P     +   A   GQ  VL+CSV 
Sbjct: 3551 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLA--PGQ-LVLECSVE 3606

Query: 539  GTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
              P P+ITW  +G  +Q  A +        L +Q     D G Y+C A NA G  S +  
Sbjct: 3607 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 3666

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
            V +H                   T P    G   + V       +  Q  G P P V W 
Sbjct: 3667 VEIH-------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWR 3707

Query: 658  HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
             +   +   S  F     G   SL IQ V  +D G Y C A NSAG  R    L V EP 
Sbjct: 3708 KDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP- 3763

Query: 717  DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKDTGHFEVLQNE 774
                P     P ++T +     L+ C  +G P P V W +DG+ L      G + +L + 
Sbjct: 3764 ----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 3819

Query: 775  DVFTLVLKKVQPWHAGQYEILLKNRVGE 802
                L+L    P  + Q+E ++ N VGE
Sbjct: 3820 ---ALLLTAPGPQDSAQFECVVSNEVGE 3844



 Score =  117 bits (293), Expect = 1e-25
 Identities = 108/407 (26%), Positives = 169/407 (41%), Gaps = 39/407 (9%)

Query: 414  PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            P  E++   + +K  + QT    C V+G P+P++ WF +G P+ R +     +       
Sbjct: 2444 PSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVL 2500

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L +L+A    +G YSC A+NA G+ +  + L V  LA   +  +  S  ++  V      
Sbjct: 2501 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNPI 2559

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
             L C     P P ITW+ +G P + +R+     G   L I +A  ED G YTC+  N LG
Sbjct: 2560 SLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 2619

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
                       E   +   E L+P + SK   P+   G+ ++K    S +T+  +    P
Sbjct: 2620 -----------EAVKNYHVEVLIPPSISKDD-PLGEVGVKEVKTKVNSTLTLECESWAVP 2667

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE------V 704
            PP + W  +G  +  S     +  G    L IQ     D+G Y C A N AGE      V
Sbjct: 2668 PPTIRWYKDGQPVTPSS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV 2725

Query: 705  RTQAVLTVQEPHDGTQPW-FISKPRSVTASL--------GQSVLISCAIAGDPFPTVHWL 755
              Q     Q+  D +  +  +S+       +             + C     P P + W 
Sbjct: 2726 LIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWY 2785

Query: 756  RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
            R+ + L        VLQ   V  + L + +  +AG+Y     N VGE
Sbjct: 2786 REDQPLSAG-DEVSVLQGGRVLQIPLVRAE--NAGRYSCKASNEVGE 2829



 Score =  117 bits (292), Expect = 1e-25
 Identities = 105/406 (25%), Positives = 158/406 (38%), Gaps = 50/406 (12%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P   S P +  V  NQT    C+  G+P P V+W  +  P+  +    E+  +     L 
Sbjct: 3673 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS---LR 3729

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            +     +D+G Y C ASN+ G       L+V  L    +APS S++     +      +L
Sbjct: 3730 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRV--LEPPAIAPSPSNL----TLTAHTPALL 3783

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDAL------PEDHGTYTCLAEN 587
             C   G+P P + W  +GQ + +     + G   L   +AL      P+D   + C+  N
Sbjct: 3784 PCEASGSPKPLVVWWKDGQKLDF---RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 3840

Query: 588  ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
             +G+      VTVH                     P      +D  V   + V +T   +
Sbjct: 3841 EVGEAHRLYQVTVH-------------------VPPTIADDQTDFTVTMMAPVVLTCHST 3881

Query: 648  GNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
            G P P V W   G ++      +     G   +L I +  P   G YTC A NSAG    
Sbjct: 3882 GIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAGVAHK 3938

Query: 707  QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766
               LTVQ       P     P  V A   + VL+ C  +G P PT+ W ++G  +     
Sbjct: 3939 HVFLTVQ-----ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 3993

Query: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              +VL       L +    P  AG Y  + KN  G    +  L++Q
Sbjct: 3994 -TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 4035



 Score =  115 bits (289), Expect = 3e-25
 Identities = 92/379 (24%), Positives = 158/379 (41%), Gaps = 42/379 (11%)

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
            +  + V   C V G P   V+W  +G P+   + ++        H L + K +  D+G +
Sbjct: 3326 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL---HGSGHTLRISKVQLADAGIF 3382

Query: 486  SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 545
            +C A++  G    ++TLQV+   V+E          D  V+ G    L C  RG P+P +
Sbjct: 3383 TCVAASPAGVADRNFTLQVQVPPVLEPV----EFQNDVVVVRGSLVELPCEARGVPLPLV 3438

Query: 546  TWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
            +W+ +G+P+     + E G   L ++     D GTY+C+A +  G+      +TV E   
Sbjct: 3439 SWMKDGEPL--LSQSLEQG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 3495

Query: 606  SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
               S         +PT         +L +  G+ + +     G P P + W  +G  +  
Sbjct: 3496 IEDS--------GQPT---------ELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 3538

Query: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             E+         +S   + +   D G YTC A + AG +     + VQ P +   P    
Sbjct: 3539 LEN---------NSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP---R 3586

Query: 726  KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
             PR V       +++ C++  +P P + W RDG  L +D  H +  +      L L+ + 
Sbjct: 3587 GPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRF--LQLQALS 3643

Query: 786  PWHAGQYEILLKNRVGECS 804
               +G Y    +N  G  S
Sbjct: 3644 TADSGDYSCTARNAAGSTS 3662



 Score =  114 bits (285), Expect = 9e-25
 Identities = 105/389 (26%), Positives = 167/389 (42%), Gaps = 45/389 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            CE  GIP P + WF    PV   E   + Y  AG   L + + + +DSG YSC ASN  G
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPGE---DTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 2430

Query: 495  QLSCSWTLQVERLAVMEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
            +   +++++V       V PS  +  + +   V++GQ   L C+V G P P++TW  +G+
Sbjct: 2431 EARRNFSVEV------LVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGR 2484

Query: 553  PIQY--ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
            P+    A      GV  L +  A     G Y+C+A NA+G           EK    +  
Sbjct: 2485 PLARGDAHHISPDGVL-LQVLQANLSSAGHYSCIAANAVG-----------EKTKHFQLS 2532

Query: 611  YLLPVAPSKPTAPIFLQGLSD-----LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
             LL        AP  L G  D     + V   + +++  +    P P + W+ +G   + 
Sbjct: 2533 VLL--------APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEA 2584

Query: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPH-DGTQPWF 723
            S +      GT H L I     ED G YTC   N  GE V+   V  +  P      P  
Sbjct: 2585 SRNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLG 2642

Query: 724  ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
                + V   +  ++ + C     P PT+ W +DG+ +   +   +VL    +  L ++ 
Sbjct: 2643 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPV-TPSSRLQVLGEGRL--LQIQP 2699

Query: 784  VQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             Q   +G+Y  +  N  GE     ++++Q
Sbjct: 2700 TQVSDSGRYLCVATNVAGEDDQDFNVLIQ 2728



 Score =  110 bits (274), Expect = 2e-23
 Identities = 90/360 (25%), Positives = 142/360 (39%), Gaps = 41/360 (11%)

Query: 464 YEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDC 523
           ++++G+    +L+A   + GTY CTA +  G      T + +   V+   P       + 
Sbjct: 473 FQESGNSSWEILRASKAEEGTYECTAVSRAG------TGRAKAQIVVTDPPPQLVPAPNV 526

Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYT 582
            V  G+  VL C V G     +TW+ + + +  +     +     L I   +P D G Y 
Sbjct: 527 TVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLSLEISGIIPTDGGRYQ 586

Query: 583 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTM 642
           C+A NA G    S W+ V E                   AP      S      G +V +
Sbjct: 587 CVASNANGVTRASVWLLVRE-------------------APQVSIHTSSQHFSQGVEVKV 627

Query: 643 TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 702
           +   SG P P + W      +QE    H + +GT   L IQ V PED G Y+C+A N  G
Sbjct: 628 SCSASGYPTPHISWSRESQALQEDSRIHVDAQGT---LIIQGVAPEDAGNYSCQATNEVG 684

Query: 703 EVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC 762
             +    L   +P     P   +    V  ++G+  ++ C  +G P P V W R G  + 
Sbjct: 685 TDQETVTLYYTDP-----PSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM- 738

Query: 763 KDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS-SARALPR 821
                    +      L +   Q   AG Y     N +G+ S ++ L + ++     LPR
Sbjct: 739 -----ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPR 793



 Score =  110 bits (274), Expect = 2e-23
 Identities = 78/289 (26%), Positives = 125/289 (43%), Gaps = 26/289 (8%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V E+  V+  CE  G+P P + WF +G  +     S +V    G   L L +A++ D+G 
Sbjct: 1514 VMEDHLVQLLCEARGVPTPNITWFKDGALLPT---STKVVYTRGGRQLQLGRAQSSDAGV 1570

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            Y+C ASNA G    +  L V     +E A     V+K    + G+   L+C  RG P P 
Sbjct: 1571 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVK---AVAGRPVALECVARGHPSPT 1627

Query: 545  ITWLLNGQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
            ++W   G P+  +  S  E   + L ++       G Y+C+A +  G+      V V   
Sbjct: 1628 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV- 1686

Query: 604  KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
                            P   +  +GL  +  + G  + +  Q SG+P P + WL NG   
Sbjct: 1687 ----------------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 1730

Query: 664  QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
            +E        +GT  +L I  V  + +G + C+A N AG    +  ++V
Sbjct: 1731 EELAGVQVASQGT--TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777



 Score =  106 bits (264), Expect = 2e-22
 Identities = 121/509 (23%), Positives = 192/509 (37%), Gaps = 60/509 (11%)

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
            + K N T+   CE   +P P + W+ +G PV      ++V  +     L +   +  DSG
Sbjct: 2650 KTKVNSTLTLECESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEG--RLLQIQPTQVSDSG 2706

Query: 484  TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA--------------VIEGQ 529
             Y C A+N  G+    + + ++   + +    FS+  +  +              ++E  
Sbjct: 2707 RYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENN 2766

Query: 530  DFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
               L C     P P +TW    QP+      +   G   L I     E+ G Y+C A N 
Sbjct: 2767 PAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNE 2826

Query: 589  LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL----QGLSDLKVMDGSQVTMTV 644
            +G+     W+            Y L V     T P+ L    + + ++ V   S V++  
Sbjct: 2827 VGE----DWL-----------HYELLVL----TPPVILGDTEELVEEVTVNASSTVSLQC 2867

Query: 645  QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 704
               GNP P + WL NG     S      + G    +   EV   D  +Y C A N AG  
Sbjct: 2868 PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV--ADAASYMCVAENQAGSA 2925

Query: 705  RTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
                 L VQ P     P         VTA L  SV + C +   P P V W +D +AL  
Sbjct: 2926 EKLFTLRVQVP-----PRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSL 2980

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL-MLQNSSARALPRG 822
                 EV       TL L + +   +G Y     N  G     V L +L   + R  PRG
Sbjct: 2981 GE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRG 3037

Query: 823  REPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH 882
             + A    +  G        +D        W   GQ  +  +  + +RG  +  ++  Q 
Sbjct: 3038 PQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQV 3095

Query: 883  TEEAIRQQEVEQLDFRDLLGKKVSTKTLS 911
            +++ +   +V      ++ G+ V T TL+
Sbjct: 3096 SDKGLYSCKVS-----NVAGEAVRTFTLT 3119



 Score =  105 bits (263), Expect = 3e-22
 Identities = 172/797 (21%), Positives = 286/797 (35%), Gaps = 153/797 (19%)

Query: 97   HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
            H ++ G  + E    S A + T E T             VS+    R  A  V T P   
Sbjct: 472  HFQESGNSSWEILRASKAEEGTYECTA------------VSRAGTGRAKAQIVVTDP--- 516

Query: 157  GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
               PP+       V V  G+    SC++ G     +TW++ +  + P++   V++   + 
Sbjct: 517  ---PPQLVPA-PNVTVSPGETAVLSCRVLGEAPYNLTWVR-DWRVLPASTGRVAQLADLS 571

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ-----GLDSANRSFVR--ETKATNS 269
             LEI G+   D G Y C+  N +G    S  L ++      + ++++ F +  E K + S
Sbjct: 572  -LEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCS 630

Query: 270  DVRKEVTNV--------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
                   ++        + ++S++             +P+  G+    A ++    +E+ 
Sbjct: 631  ASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETV 690

Query: 322  LESCKDSPRTAPQTPVLQKT--SSSITLQAARVQPEPRA----PGLG-VLSPSGEERKRP 374
                 D P  +    V+       ++ +  A   P PR      GL  +L+P G    + 
Sbjct: 691  TLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKL 750

Query: 375  APPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFR 434
              P       R  G  +   V++  +    ++     A P+    P+   V+  ++    
Sbjct: 751  RIP---AAQERDAGTYTCRAVNELGDASAEIQLAVGHA-PQLTELPRDVTVELGRSALLA 806

Query: 435  CEVSGIPKPEVAWFL-EGTPVRRQ----EGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489
            C  +G P P V W   +G P+  +     GS     D+G   L        D   Y C A
Sbjct: 807  CRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG--VLFFESVAPEDQAPYVCEA 864

Query: 490  SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV-RGTPVPRITWL 548
             N  G++     L V   A  ++A S  +V     V+EGQ   L C V  G P+P   WL
Sbjct: 865  RNVFGKVQAEARLIVTGHAPPQIASSAPTV----RVLEGQPVSLPCIVLAGRPLPERHWL 920

Query: 549  LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
             +G+P+             LH+  AL E  G Y+C+A N  G                R 
Sbjct: 921  KDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG-------------SQHRD 967

Query: 609  SEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI-QES 666
             E ++ V P   PTA   +         +G   ++    SG P P + W    N +    
Sbjct: 968  VELVVQVPPRIHPTATHHITN-------EGVPASLPCVASGVPAPTITWTKETNALTSRG 1020

Query: 667  EDFHFEQRGT-------------------------------------------------- 676
              ++  + GT                                                  
Sbjct: 1021 PHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLP 1080

Query: 677  QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQ 736
              SL + +V   D+G Y C A N AG    + VL VQ P     P     PR +   +G+
Sbjct: 1081 SGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVP-----PQVQPGPRVLKVLVGE 1135

Query: 737  SVLISCAIAGDPFPTVHWLRDGKAL----CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
            ++ ++C   G+P P + W +DG  L     + + HF  ++  D             AG+Y
Sbjct: 1136 ALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRTSD-------------AGRY 1182

Query: 793  EILLKNRVGECSCQVSL 809
                 N  G  + +V L
Sbjct: 1183 RCEASNSAGVDAWEVEL 1199



 Score =  103 bits (256), Expect = 2e-21
 Identities = 99/411 (24%), Positives = 165/411 (40%), Gaps = 64/411 (15%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPV--RRQEGSIEVYEDAGSHY 471
            P+ +  P+  +V   + +   C   G P+P+++W  +G  +  R  +GS+        H+
Sbjct: 1120 PQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSV--------HF 1171

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
              +   RT D+G Y C ASN+ G    +W +++  L         +S L +   + G++ 
Sbjct: 1172 AAI---RTSDAGRYRCEASNSAG--VDAWEVELRVLEPPHWGADETSGLLE--RVAGENA 1224

Query: 532  VLQCSVRGTPVPRITWL-------LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 584
             L C  RGTP P++TW        L+GQP     +  E G   L +    P D G Y C 
Sbjct: 1225 SLPCPARGTPKPQVTWRKGPSSEPLHGQP---GVAVLEEG--SLFLASVSPADSGDYECQ 1279

Query: 585  AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTV 644
            A N +G  S  A + V+   S R+                     +++  M G  +T+  
Sbjct: 1280 ATNEVGSTSRRAKLVVYVPPSIRED-----------------GRKANVSGMAGQSLTLEC 1322

Query: 645  QVSGNPPPEVIWLHNGNEI-------QESEDFHFEQRGTQ------HSLCIQEVFPEDTG 691
              +G P PE++WL +   +           D  + Q G         SL    +   D+G
Sbjct: 1323 DANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSG 1382

Query: 692  TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
             Y+C A N AG  +    L V  P            + V    G  V + C  +G P P 
Sbjct: 1383 LYSCRAENQAGTAQRDFHLLVLTP---PSVLGAGAAQEVLGLAGADVELQCWTSGVPTPQ 1439

Query: 752  VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
            V W +D + +     H +V ++  V  +    V     G+Y+ +  +  G+
Sbjct: 1440 VEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--GDEGRYQCVAFSPAGQ 1488



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 100/403 (24%), Positives = 152/403 (37%), Gaps = 52/403 (12%)

Query: 429  QTVKFRCEVSGIPKPEVAWF----LEGTPVR----------RQEGSIEVYEDAGSHYLCL 474
            Q++   C+ +G P PE+ W     L G P+            Q G   + ++  S  L  
Sbjct: 1316 QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS--LHF 1373

Query: 475  LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
             + +  DSG YSC A N  G     + L V     +  A +   VL     + G D  LQ
Sbjct: 1374 PRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLG----LAGADVELQ 1429

Query: 535  CSVRGTPVPRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
            C   G P P++ W  + QP+         +     L I  +   D G Y C+A +  GQ 
Sbjct: 1430 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 1489

Query: 593  SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG---LSDLKVMDGSQVTMTVQVSGN 649
            +    + VH                    AP  + G     ++ VM+   V +  +  G 
Sbjct: 1490 ARDFQLRVH--------------------APPTIWGSNETGEVAVMEDHLVQLLCEARGV 1529

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            P P + W  +G  +  S    + + G Q  L +      D G YTC+A N+ G       
Sbjct: 1530 PTPNITWFKDGALLPTSTKVVYTRGGRQ--LQLGRAQSSDAGVYTCKASNAVGAAEKATR 1587

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            L V  P   T      +P  V A  G+ V + C   G P PT+ W  +G  + +     E
Sbjct: 1588 LDVYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN---E 1642

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
                 D   L L+      +G Y  +  +  GE   Q S+ +Q
Sbjct: 1643 SRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 1685



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 107/408 (26%), Positives = 149/408 (36%), Gaps = 33/408 (8%)

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            +P   +    + V   C   G P P ++W  EG PV   E +    E  GS  L L    
Sbjct: 1602 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVA--ESNESRLETDGS-VLRLESPG 1658

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
               SG YSC AS+  G+    ++++V+    + VA     V      I GQ   L C   
Sbjct: 1659 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQAS 1714

Query: 539  GTPVPRITWLLNGQPIQYARSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
            G+PVP I WL NG+P +       A     LHI     +  G + C A N  G       
Sbjct: 1715 GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE 1774

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPI-----FLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
            V+VH +            AP     PI       +  S         V         PP 
Sbjct: 1775 VSVHGE-----------WAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPL 1823

Query: 653  EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
               W   G+   E              L I++V   D G YTC A N AGE + +  L V
Sbjct: 1824 VEGWCSPGSLWGEPTGIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV 1882

Query: 713  QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
              P    +P  ++K     A    SV + C  +G P P V W +  + +    G   V  
Sbjct: 1883 LVP-PNIEPGPVNKAVLENA----SVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTV 1934

Query: 773  NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
            + D   L +++ Q   AG Y  +  N  G    +  L +       LP
Sbjct: 1935 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP 1982



 Score = 91.3 bits (225), Expect = 8e-18
 Identities = 90/313 (28%), Positives = 127/313 (40%), Gaps = 43/313 (13%)

Query: 454  VRRQEGSIEVYEDAG---SHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
            V R   S  V+E+ G   S  L L + +  DSG Y CTASN  G  S  + L V+    +
Sbjct: 1063 VNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQV 1122

Query: 511  EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570
            +  P    VLK   V+ G+   L C   G P P+++W  +G  +Q          A +  
Sbjct: 1123 QPGPR---VLK---VLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRT 1176

Query: 571  QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
             DA     G Y C A N+ G     AW            E  L V            GL 
Sbjct: 1177 SDA-----GRYRCEASNSAG---VDAW------------EVELRVLEPPHWGADETSGL- 1215

Query: 631  DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT----QHSLCIQEVF 686
             L+ + G   ++     G P P+V W    +    SE  H  Q G     + SL +  V 
Sbjct: 1216 -LERVAGENASLPCPARGTPKPQVTWRKGPS----SEPLH-GQPGVAVLEEGSLFLASVS 1269

Query: 687  PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG 746
            P D+G Y C+A N  G    +A L V  P    +     +  +V+   GQS+ + C   G
Sbjct: 1270 PADSGDYECQATNEVGSTSRRAKLVVYVPPSIRED---GRKANVSGMAGQSLTLECDANG 1326

Query: 747  DPFPTVHWLRDGK 759
             P P + WL+D +
Sbjct: 1327 FPVPEIVWLKDAQ 1339



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 68/238 (28%), Positives = 93/238 (39%), Gaps = 43/238 (18%)

Query: 20  DPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGR 78
           D S    + +  AP     PR++ ++ G +A    R  G P P VTW R +GQP+  G R
Sbjct: 773 DASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPL--GLR 830

Query: 79  FLLDCGIRG----TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
                G R     +  L   +V  ED+  Y CEA N  G  Q                  
Sbjct: 831 LGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ------------------ 872

Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSC-KITGRPQPQVT 193
                          E R  + G  PP+ A+    V V EGQ     C  + GRP P+  
Sbjct: 873 --------------AEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERH 918

Query: 194 WLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
           WLK   PL P +R S+        L +    Q+  G Y+C+  N +G      EL +Q
Sbjct: 919 WLKDGRPLPPGSRHSIRADGS---LHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 973



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 60/394 (15%)

Query: 429  QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
            Q ++  C+ SG P P + W   G P     G     +    H   +       SG ++C 
Sbjct: 1705 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH---IDHVELDHSGLFACQ 1761

Query: 489  ASNAQGQLSCSWTLQVERLAVMEVAPSFSSV---LKDCAVIEGQDFVLQCS--------- 536
            A+N  G        +VE     E AP    V              F   C          
Sbjct: 1762 ATNEAGTAGA----EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGA 1817

Query: 537  ------VRGTPVPRITW-LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
                  V G   P   W    G P+ Y+          L I+     D G YTC A N  
Sbjct: 1818 HPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP------PLQIEKVDLRDEGIYTCAATNLA 1871

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
            G+             S R+    + V P+    P+      +  V++ + VT+    SG 
Sbjct: 1872 GE-------------SKREVALKVLVPPNIEPGPV------NKAVLENASVTLECLASGV 1912

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
            PPP+V W      +           G    L I++    D G+Y C A N AG    +  
Sbjct: 1913 PPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 1970

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC-KDTGHF 768
            L V  P   T P  +  P  V       V ++C   G P PT+ WL+DG  +    T   
Sbjct: 1971 LRVNVPPRITLPPSLPGPVLVNT----PVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGL 2026

Query: 769  EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
            +V     V TL   +     +G+Y  +  + VGE
Sbjct: 2027 QVFPGGRVLTLASARAS--DSGRYSCVAVSAVGE 2058



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 59/214 (27%), Positives = 86/214 (40%), Gaps = 42/214 (19%)

Query: 33   PAFILPPRN----LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
            PAF   PR     + ++ G  A         PEP VTW+++GQP+    R      +RG 
Sbjct: 3029 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQR---TQALRGG 3085

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              L I      D+G Y+C+ +N +G    T  LTV+               +   F  P 
Sbjct: 3086 QRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ---------------VPPTFENPK 3130

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
             ET   + G   P   T                C ++G P P VTWLK  +P++ SA   
Sbjct: 3131 TETVSQVAGS--PLVLT----------------CDVSGVPAPTVTWLKDRMPVESSAVHG 3172

Query: 209  VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
            V  + G   L++  +     G YTC+  N   +A
Sbjct: 3173 VVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEA 3204



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 59/207 (28%), Positives = 83/207 (40%), Gaps = 42/207 (20%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL---DCGIRGTFSLVIHAVHEEDRGK 103
            GA  + +    G P PQV W ++ QP+  GG  L    D  +     L I   H  D G+
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV-----LRITGSHVGDEGR 1477

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y C A + +G +    +L V                      AP     P+IWG      
Sbjct: 1478 YQCVAFSPAGQQARDFQLRVH---------------------AP-----PTIWG------ 1505

Query: 164  ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
            + + G V V E  + +  C+  G P P +TW K    L  S +V V  + G Q L++   
Sbjct: 1506 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGGRQ-LQLGRA 1563

Query: 224  NQDDVGVYTCLVVNGSGKASMSAELSI 250
               D GVYTC   N  G A  +  L +
Sbjct: 1564 QSSDAGVYTCKASNAVGAAEKATRLDV 1590



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 35/220 (15%)

Query: 32   APAFIL-PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            AP F L     L ++EG         RG P P+++W ++GQP+   G  L      G   
Sbjct: 2161 APVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL- 2219

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L +        G YTCE +N  G     ++L                           V 
Sbjct: 2220 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQL--------------------------EVH 2253

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
              P I G   P         VV++G +    C  TG+P P VTW +   P+   A + + 
Sbjct: 2254 VPPQIAGPREPPTQVS----VVQDG-VATLECNATGKPPPTVTWERDGQPV--GAELGLQ 2306

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             +N  Q L +        G Y+C+  N +G+A    ELS+
Sbjct: 2307 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 2346



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 62/246 (25%), Positives = 93/246 (37%), Gaps = 48/246 (19%)

Query: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
            A + + +T  +V    V   P+ +  AF      L    G + + +  VRG P P + W 
Sbjct: 4199 AENRVGRTQ-AVSFVHVKEAPVLQGEAFSY----LVEPVGGSIQLDCVVRGDPVPDIHWI 4253

Query: 68   RNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
            ++G P+     R  L  G     SL IH    +D G+Y C A N  G  +  V L ++  
Sbjct: 4254 KDGLPLRGSHLRHQLQNG-----SLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQ-- 4306

Query: 127  FAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
                              SAP  +  P                + V+ G      C+ TG
Sbjct: 4307 ------------------SAPVFQVEPQ--------------DMTVRSGDDVALRCQATG 4334

Query: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
             P P + WL+   PL+ S R+          L +  V   D G Y C+  N  G A+  A
Sbjct: 4335 EPTPTIEWLQAGQPLRASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSATARA 4391

Query: 247  ELSIQG 252
             L ++G
Sbjct: 4392 FLVVRG 4397



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 57/238 (23%), Positives = 91/238 (38%), Gaps = 52/238 (21%)

Query: 16   SLSVDPSRVDSM-PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
            S+ V P  +  + PLT   A +  P  L  +            G P P + W R  +P++
Sbjct: 2345 SVLVPPELIGDLDPLTNITAALHSPLTLLCE----------AMGIPPPAIRWFRGEEPVS 2394

Query: 75   SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLG 132
             G    L   + G + L +    E+D G Y+C A+N  G   R  +VE+ V  S   +  
Sbjct: 2395 PGEDTYL---LAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDL 2451

Query: 133  QPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192
            + V+                                   V +GQ     C +TG PQP++
Sbjct: 2452 EEVIK----------------------------------VLDGQTAHLMCNVTGHPQPKL 2477

Query: 193  TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            TW K   PL       +S      +L++   N    G Y+C+  N  G+ +   +LS+
Sbjct: 2478 TWFKDGRPLARGDAHHISPDG--VLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 2533



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 46/214 (21%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG----RFLLDCGIRGTFSLVIHAVHEE 99
            + EG   + +    G P P V W ++G P+        RF LD G     SLV+  +   
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-----SLVLKGLRAS 3283

Query: 100  DRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
            D G YTC A N +G  AR  TV + V                             P+I  
Sbjct: 3284 DAGAYTCVAHNPAGEDARLHTVNVLVP----------------------------PTI-- 3313

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
                + A   G +V + G++    C + G P   V+WLK  +PL  S R  +        
Sbjct: 3314 ---KQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HT 3368

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            L I  V   D G++TC+  + +G A  +  L +Q
Sbjct: 3369 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 3402



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 56/236 (23%), Positives = 89/236 (37%), Gaps = 36/236 (15%)

Query: 15   TSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
            T+L+ +  R  ++ +   P     P N  + E A+   E    G P P V+W +  QP++
Sbjct: 1868 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVS 1927

Query: 75   SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
            S     +    R    L I      D G Y C A+N +G+ ++   L V           
Sbjct: 1928 SWMGVTVSVDGR---VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN---------- 1974

Query: 135  VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
                        P +   PS+ G  P    T +           R +C  TG P P + W
Sbjct: 1975 ----------VPPRITLPPSLPG--PVLVNTPV-----------RLTCNATGAPSPTLMW 2011

Query: 195  LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            LK   P+ P+    +    G +VL +      D G Y+C+ V+  G+      L +
Sbjct: 2012 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 2067



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 50/197 (25%), Positives = 79/197 (40%), Gaps = 40/197 (20%)

Query: 59   YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQ 116
            +P P +TW ++G P  +     L   + GT  L I    +ED G+YTC  TN  G   + 
Sbjct: 2568 FPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 2624

Query: 117  VTVELTVEGSFAKQ--LGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKE 174
              VE+ +  S +K   LG+  V +                          TK+   +  E
Sbjct: 2625 YHVEVLIPPSISKDDPLGEVGVKEV------------------------KTKVNSTLTLE 2660

Query: 175  GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
                   C+    P P + W K   P+ PS+R+ V  +   ++L+I      D G Y C+
Sbjct: 2661 -------CESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG--RLLQIQPTQVSDSGRYLCV 2711

Query: 235  VVNGSGKASMSAELSIQ 251
              N +G+      + IQ
Sbjct: 2712 ATNVAGEDDQDFNVLIQ 2728



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 36/213 (16%)

Query: 38   PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
            PP  + + +   A  E    G P P VTW R+GQP+  G    L    +G  SL +    
Sbjct: 2264 PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQ-SLHVERAQ 2320

Query: 98   EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
                G+Y+C A N +G  +   EL                          +V   P + G
Sbjct: 2321 AAHTGRYSCVAENLAGRAERKFEL--------------------------SVLVPPELIG 2354

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
            +  P     L  +           C+  G P P + W +G  P+ P     +    G  +
Sbjct: 2355 DLDP-----LTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA--GGWM 2407

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            L++    + D G+Y+CL  N +G+A  +  + +
Sbjct: 2408 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 2440



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 54/213 (25%), Positives = 85/213 (39%), Gaps = 42/213 (19%)

Query: 29  LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIRG 87
           +T+ P  ++P  N+ +  G TA    RV G     +TW R+ + +  S GR      +  
Sbjct: 513 VTDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADL-- 570

Query: 88  TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
             SL I  +   D G+Y C A+N +G  + +V L V  +       P VS     +  + 
Sbjct: 571 --SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREA-------PQVSIHTSSQHFSQ 621

Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
            VE +                            SC  +G P P ++W + +  LQ  +R+
Sbjct: 622 GVEVK---------------------------VSCSASGYPTPHISWSRESQALQEDSRI 654

Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
            V  +     L I GV  +D G Y+C   N  G
Sbjct: 655 HVDAQG---TLIIQGVAPEDAGNYSCQATNEVG 684



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 34/199 (17%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
            + +G TA     V G+P+P++TW ++G+P+  G    +     G    V+ A +    G 
Sbjct: 2457 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD--GVLLQVLQA-NLSSAGH 2513

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y+C A N  G +    +L+V       L  P +   LG    +   E             
Sbjct: 2514 YSCIAANAVGEKTKHFQLSV-------LLAPTI---LGGAEDSADEE------------- 2550

Query: 164  ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
                  V V         C+    P P +TW+K   P + S  + +    G   L+I   
Sbjct: 2551 ------VTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNA 2602

Query: 224  NQDDVGVYTCLVVNGSGKA 242
             ++D G YTC+V N  G+A
Sbjct: 2603 QKEDAGQYTCVVTNELGEA 2621



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 44/224 (19%)

Query: 31   EAPAFILPPRNLCIKEGATAK---FEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
            +AP  I+ PR      G        E  V   P P++TWHR+G  +            RG
Sbjct: 3577 QAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFP--ERG 3634

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
             F L + A+   D G Y+C A N +G+  V   + +                     + P
Sbjct: 3635 RF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH--------------------TVP 3673

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SAR 206
             + + P                V V   Q     C+  G P P V+W K  VPL P S R
Sbjct: 3674 TIRSGPP--------------AVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR 3719

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
              +  +     L I  V   D G Y CL  N +G      +L +
Sbjct: 3720 FEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 3760



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 9/153 (5%)

Query: 662 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQP 721
           E +  E+ HF++ G   S  I      + GTY C A + AG  R +A + V +P     P
Sbjct: 464 EARLGEERHFQESGNS-SWEILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDP----PP 518

Query: 722 WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 781
             +  P +VT S G++ ++SC + G+    + W+RD + L   TG    L +    +L +
Sbjct: 519 QLVPAP-NVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD---LSLEI 574

Query: 782 KKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
             + P   G+Y+ +  N  G     V L+++ +
Sbjct: 575 SGIIPTDGGRYQCVASNANGVTRASVWLLVREA 607



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 61/228 (26%), Positives = 82/228 (35%), Gaps = 46/228 (20%)

Query: 30  TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
           T+ P+       + +  G  A       G P P+V W+R G         +L      + 
Sbjct: 695 TDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGL------EMILAPEGSSSG 748

Query: 90  SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
            L I A  E D G YTC A N  G     ++L V                          
Sbjct: 749 KLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV-------------------------- 782

Query: 150 ETRPSIWGECPPKFATKLGR-VVVKEGQMGRFSCKITGRPQPQVTWLKGN-VPL---QPS 204
                  G  P    T+L R V V+ G+    +C+ TGRP P VTW +G+  PL     +
Sbjct: 783 -------GHAPQ--LTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGA 833

Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252
            R S S +    VL    V  +D   Y C   N  GK    A L + G
Sbjct: 834 GRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTG 881



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 51/279 (18%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            +P  K     V     +++LL C+ S  P  TI W   G  + T     +   G L    
Sbjct: 3947 SPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL---R 4003

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP----- 1211
            I  A PED G Y C+AKN AG A    ++ V   P  EN       +    + LP     
Sbjct: 4004 IAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG 4063

Query: 1212 -------------PVLGTESDATVKK--------------------------KPAPKTPP 1232
                         PV G E   T++                           +   +   
Sbjct: 4064 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 4123

Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
               + P     P D+ +R G+ + L     G+      W    + + E     V   + G
Sbjct: 4124 TILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG 4179

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            S L   A  +E  G Y    EN++G  QA   + V + P
Sbjct: 4180 STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 4218



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 41/195 (21%)

Query: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
            VRG P   V+W ++G P+    R LL        +L I  V   D G +TC A + +G  
Sbjct: 3337 VRGSPPIHVSWLKDGLPLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGV- 3392

Query: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
                    + +F  Q+  P            P +E         P +F      VVV  G
Sbjct: 3393 -------ADRNFTLQVQVP------------PVLE---------PVEFQND---VVVVRG 3421

Query: 176  QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
             +    C+  G P P V+W+K   PL     +S S + G   L++  V   D G Y+C+ 
Sbjct: 3422 SLVELPCEARGVPLPLVSWMKDGEPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVA 3475

Query: 236  VNGSGKASMSAELSI 250
            V+ +G+A    +L++
Sbjct: 3476 VSEAGEARRHFQLTV 3490



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 48/201 (23%)

Query: 57   RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
            RG P P +TW ++G  + +  + +     RG   L +      D G YTC+A+N  GA +
Sbjct: 1527 RGVPTPNITWFKDGALLPTSTKVVYT---RGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 1583

Query: 117  VTVEL------TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
                L      T+EG+     G+P V K +                           GR 
Sbjct: 1584 KATRLDVYVPPTIEGAG----GRPYVVKAVA--------------------------GRP 1613

Query: 171  VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
            V  E       C   G P P ++W    +P+  S   S  E +G  VL +    +   G+
Sbjct: 1614 VALE-------CVARGHPSPTLSWHHEGLPVAESNE-SRLETDG-SVLRLESPGEASSGL 1664

Query: 231  YTCLVVNGSGKASMSAELSIQ 251
            Y+C+  + +G+A +   + +Q
Sbjct: 1665 YSCVASSPAGEAVLQYSVEVQ 1685



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 53/220 (24%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPI----------------TSGGRFLLDCGIRGTFS 90
            G +   E    G+P P++ W ++ Q +                  GG  LLD G     S
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ----S 1370

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L    + E D G Y+C A N +G  Q    L                           V 
Sbjct: 1371 LHFPRIQEGDSGLYSCRAENQAGTAQRDFHL--------------------------LVL 1404

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
            T PS+ G      A     V+   G      C  +G P PQV W K   P+ P       
Sbjct: 1405 TPPSVLG------AGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV 1458

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            +++G QVL I G +  D G Y C+  + +G+ +   +L +
Sbjct: 1459 QEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV 1497



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 61/259 (23%), Positives = 96/259 (37%), Gaps = 54/259 (20%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQD----VHVAEGKKLLLQCQVSSDPPATIIWT 1132
            C+  +A   D +    S    PAF+Q  +     V V  G K +L C+  + P  T+ W 
Sbjct: 3008 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 3067

Query: 1133 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
             +G+ L   +     + G    + I++A   D+GLY C   N AG+A  +  +TV   P 
Sbjct: 3068 KDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPT 3125

Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
             EN K                  TE+ + V                            AG
Sbjct: 3126 FENPK------------------TETVSQV----------------------------AG 3139

Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
              + L   V+G    T TW+K R  ++ S    V +   G +L +   +    G YT + 
Sbjct: 3140 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVA 3197

Query: 1313 ENKLGSRQAQVNLTVVDKP 1331
            EN     +    + V+  P
Sbjct: 3198 ENTQAEARKDFVVAVLVAP 3216



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 85/345 (24%), Positives = 123/345 (35%), Gaps = 83/345 (24%)

Query: 1076 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1135
            +C+  +   TD E  +      P+       V VA G++ +L C+ S  PP  +IW   G
Sbjct: 676  SCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGG 735

Query: 1136 KTLKTTKFIILSQEGSLCS-VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--- 1191
              +      IL+ EGS    + I  A   D G Y C A N+ G A    Q+ V  AP   
Sbjct: 736  LEM------ILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLT 789

Query: 1192 ----------------ASENTKAPE----------------------MKSRRPKSSLPPV 1213
                            A   T  P                        +SR+P S    V
Sbjct: 790  ELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSG---V 846

Query: 1214 LGTESDATVKKKP--------APKTPPKAAM------PPQIIQFPEDQKVRAGESVELFG 1259
            L  ES A   + P          K   +A +      PPQI       +V  G+ V L  
Sbjct: 847  LFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPC 906

Query: 1260 KVTGTQPI-TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGS 1318
             V   +P+    W+K  + +       +    +GS L +  A QEH G Y+ +  N  GS
Sbjct: 907  IVLAGRPLPERHWLKDGRPLPPGSRHSIR--ADGS-LHLDRALQEHAGRYSCVATNTAGS 963

Query: 1319 RQAQVNLTV-------------VDKPDPPAGTPC-ASDIRSSSLT 1349
            +   V L V             +     PA  PC AS + + ++T
Sbjct: 964  QHRDVELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTIT 1008



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
            +  G+ T      + E+ +D   A L A     P ++   S   R+  V+EG   R DC+
Sbjct: 3188 AQAGTYTCVAENTQAEARKDFVVAVLVA-----PRIRS--SGVAREHHVLEGQEVRLDCE 3240

Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P+V W KD   + +     + +  DG  SL++  +   D   YTC A N  GE
Sbjct: 3241 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLRASDAGAYTCVAHNPAGE 3298



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            +AP F+ + QD+ V  G  + L+CQ + +P  TI W   G+ L+ ++ +    +GSL   
Sbjct: 4307 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLE 4366

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
            ++E     D G Y CVA N  G A     + V   P
Sbjct: 4367 NVETG---DAGTYDCVAHNLLGSATARAFLVVRGEP 4399



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 62/282 (21%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L  V    G+ L L CQ S  P  TI W  NG+  +    + ++ +G+  ++ I+    +
Sbjct: 1696 LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT--TLHIDHVELD 1753

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD--------DAPASENTKAPEMKSRRPKSSLPP--- 1212
              GL+ C A N+AG A    +V+V         + P  +     E  S  P +  PP   
Sbjct: 1754 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 1813

Query: 1213 ----------VLGTESDATVKKKP-----APKTPP------------------------- 1232
                      V G  S  ++  +P     A   PP                         
Sbjct: 1814 GWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE 1873

Query: 1233 -------KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                   K  +PP I   P ++ V    SV L    +G  P   +W K  + +  S  M 
Sbjct: 1874 SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMG 1931

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            V  S +G  L I  A+    G Y  +  N  GS + +  L V
Sbjct: 1932 VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 1973



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 53/285 (18%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            V V +     L+C  +  PP T+ W  +G+ +     + L  +G   S+ +E+A     G
Sbjct: 2268 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTG 2325

Query: 1167 LYKCVAKNDAGQAECSCQVTV--------DDAPASENTKA----------------PEMK 1202
             Y CVA+N AG+AE   +++V        D  P +  T A                P ++
Sbjct: 2326 RYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 2385

Query: 1203 SRRPKSSLPPVLGT---------------ESDATVKKKPAPKTPPKA--------AMPPQ 1239
              R +  + P   T               E D+ +    A     +A         +PP 
Sbjct: 2386 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 2445

Query: 1240 I--IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
            I      E  KV  G++  L   VTG      TW K  + +   +   +  S +G  L +
Sbjct: 2446 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHI--SPDGVLLQV 2503

Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
            L A     G Y+ +  N +G +     L+V+  P    G   ++D
Sbjct: 2504 LQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 2548



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 54/255 (21%)

Query: 2    GDVKLVASSHISKTSLSVD-----PSRVDSMPLTEAPAFI-LPPRNLCIKEGATAKFEGR 55
            G  + VAS+    T L        P R+   P    P  +  P R  C   GA       
Sbjct: 1952 GSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA------- 2004

Query: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
                P P + W ++G P++  G   L     G   L + +    D G+Y+C A +  G  
Sbjct: 2005 ----PSPTLMWLKDGNPVSPAGTPGLQV-FPGGRVLTLASARASDSGRYSCVAVSAVGED 2059

Query: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
            +  V L V                             PSI GE       +L   VV   
Sbjct: 2060 RQDVVLQVH--------------------------MPPSILGE-------ELNVSVVANE 2086

Query: 176  QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
             +    C+    P P ++W K   PL+P   V +S    +  L++   +  D G YTC  
Sbjct: 2087 SVA-LECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEA 2143

Query: 236  VNGSGKASMSAELSI 250
            +N +G +     L++
Sbjct: 2144 LNQAGHSEKHYNLNV 2158



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P     + DL   EGS A   CK  G P+P + W KD Q +  +   +  +    +  
Sbjct: 4036 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA---EGKFTIQPSGE 4092

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            L++ ++ G D   YTC A N++G A     L +
Sbjct: 4093 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 55/233 (23%), Positives = 89/233 (38%), Gaps = 41/233 (17%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            +++V       L L+C+  + PP TI W  +G+ +  +  + +  EG L  + I+     
Sbjct: 2646 VKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQIQPTQVS 2703

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAP----ASENTKAPEMKSRRPKSSLPPVLGTESD 1219
            D G Y CVA N AG+ +    V +   P      + + A E+ SR  ++       TE  
Sbjct: 2704 DSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV---TEYR 2760

Query: 1220 ATVKKKPA-PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1278
              V+  PA       A  PP +  + EDQ + AG+ V +                     
Sbjct: 2761 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVL-------------------- 2800

Query: 1279 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
                       + G  L I   R E+ G Y+    N++G       L V+  P
Sbjct: 2801 -----------QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP 2842



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 59/256 (23%), Positives = 96/256 (37%), Gaps = 56/256 (21%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            + V +G+   L C V+  P   + W  +G+ L       +S +G L  V   +A     G
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL--QANLSSAG 2512

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
             Y C+A N  G+     Q++V  AP                     +LG   D+      
Sbjct: 2513 HYSCIAANAVGEKTKHFQLSVLLAPT--------------------ILGGAEDSA----- 2547

Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                              E+  V     + L  +         TWMK     + S ++++
Sbjct: 2548 -----------------DEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL 2590

Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----DPPAGTPCASD 1342
                +G  L IL A++E  G YT +V N+LG      ++ V+  P    D P G     +
Sbjct: 2591 LPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKE 2648

Query: 1343 IR---SSSLTL---SW 1352
            ++   +S+LTL   SW
Sbjct: 2649 VKTKVNSTLTLECESW 2664



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 43/208 (20%), Positives = 71/208 (34%), Gaps = 40/208 (19%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
            +   +T   +    G P P ++W +NG P +   R  +   +     L +      D   
Sbjct: 2857 VNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQV---LEDGQVLQVSTAEVADAAS 2913

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y C A N +G+ +    L V                                  + PP+ 
Sbjct: 2914 YMCVAENQAGSAEKLFTLRV----------------------------------QVPPRI 2939

Query: 164  A-TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
            A   L +V           C +   P P+VTW K +  L     V +    G   L++  
Sbjct: 2940 AGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLP--GTHTLQLGR 2997

Query: 223  VNQDDVGVYTCLVVNGSGKASMSAELSI 250
                D G+YTC  +N +G+     +LS+
Sbjct: 2998 ARLSDSGMYTCEALNAAGRDQKLVQLSV 3025



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 52/234 (22%), Positives = 83/234 (35%), Gaps = 69/234 (29%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G  + L C V  DP   I W  +G  L+ +      Q GSL   +I +   +D G Y+C+
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSL---TIHRTERDDAGRYQCL 4289

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A+N+ G A+    + +  AP  +                                     
Sbjct: 4290 AENEMGVAKKVVILVLQSAPVFQVE----------------------------------- 4314

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK------ 1285
                        P+D  VR+G+ V L  + TG    T  W++  + ++ S  ++      
Sbjct: 4315 ------------PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS 4362

Query: 1286 --VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
              +EN E G             G Y  +  N LGS  A+  L V  +P    G+
Sbjct: 4363 LWLENVETGD-----------AGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS 4405



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 60/269 (22%), Positives = 98/269 (36%), Gaps = 50/269 (18%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V+ G+  +L C+V  + P  + W  + + L  +   + +Q   L S+ I   +P D 
Sbjct: 525  NVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRV-AQLADL-SLEISGIIPTDG 582

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP---------------------ASENTKAPEMKSR 1204
            G Y+CVA N  G    S  + V +AP                     ++     P +   
Sbjct: 583  GRYQCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWS 642

Query: 1205 RPKSSLPPVLGTESDA---TVKKKPAPKTPPKAAM-------------------PPQIIQ 1242
            R   +L        DA    + +  AP+     +                    PP +  
Sbjct: 643  RESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSA 702

Query: 1243 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1302
                  V  GE   L  + +G  P    W +   ++     +  E S +G KL I AA++
Sbjct: 703  VNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEM----ILAPEGSSSG-KLRIPAAQE 757

Query: 1303 EHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
               G YT    N+LG   A++ L V   P
Sbjct: 758  RDAGTYTCRAVNELGDASAEIQLAVGHAP 786



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 26/98 (26%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
            V++A +  +  E P V  + S         +G   +  C   GYP P + W ++ Q+++E
Sbjct: 595  VTRASVWLLVREAPQVSIHTSSQ----HFSQGVEVKVSCSASGYPTPHISWSRESQALQE 650

Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
                 +    D   +LII  V  +D   Y+C+A N +G
Sbjct: 651  DSRIHV----DAQGTLIIQGVAPEDAGNYSCQATNEVG 684



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 48/218 (22%), Positives = 78/218 (35%), Gaps = 44/218 (20%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            AP         H ++G ++ + C  S  P   I W+   + L+    I +  +G+L    
Sbjct: 607  APQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLI--- 663

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK-------SS 1209
            I+   PED G Y C A N+ G  + +  +   D P+     A  + +   +       S 
Sbjct: 664  IQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASG 723

Query: 1210 LPP------------VLGTESDATVKKK-PAPKTPPKAAM-------------------- 1236
            +PP            +L  E  ++ K + PA +                           
Sbjct: 724  VPPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVG 783

Query: 1237 -PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1273
              PQ+ + P D  V  G S  L  + TG  P T TW +
Sbjct: 784  HAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRR 821



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 48/219 (21%)

Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
            V E   + L+C  S  PP  + W    + + +   + +S +G +  + IE+A   D G Y
Sbjct: 1897 VLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSY 1954

Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
            +CVA N AG  E    + V+                                        
Sbjct: 1955 RCVASNVAGSTELRYGLRVN---------------------------------------- 1974

Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              PP+  +PP +        V     V L    TG    T  W+K    +  +    ++ 
Sbjct: 1975 -VPPRITLPPSL-----PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 2028

Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               G  LT+ +AR    G Y+ +  + +G  +  V L V
Sbjct: 2029 FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 2067



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 49/220 (22%), Positives = 83/220 (37%), Gaps = 53/220 (24%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G+ + + C V   PP  + W  +G  L  ++  +L   GS  ++ I K    D G++ CV
Sbjct: 3328 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--HGSGHTLRISKVQLADAGIFTCV 3385

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A + AG A+ +  + V                      +PPVL                 
Sbjct: 3386 AASPAGVADRNFTLQV---------------------QVPPVL----------------- 3407

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                   + ++F  D  V  G  VEL  +  G      +WMK      + E +  ++ E 
Sbjct: 3408 -------EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK------DGEPLLSQSLEQ 3454

Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            G  L + A      G Y+ +  ++ G  +    LTV++ P
Sbjct: 3455 GPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPP 3494



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 21/228 (9%)

Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAE---------TLKPMGNAKPDEN 1058
            V    P +   P GP   VG A     L+    A+PA           L+   + +  E 
Sbjct: 3574 VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER 3633

Query: 1059 LKSASKEELKKDVKNDVNCK-RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLL 1117
             +    + L      D +C  R  AG+T    R E   T P  +     V+V+  +  LL
Sbjct: 3634 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-TVPTIRSGPPAVNVSVNQTALL 3692

Query: 1118 QCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
             CQ    P   + W  +   L  ++ +F IL  EGSL    I+  L +D G Y C+A N 
Sbjct: 3693 PCQADGVPAPLVSWRKDRVPLDPRSPRFEILP-EGSL---RIQPVLAQDAGHYLCLASNS 3748

Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            AG       + V + PA     AP   +    +  P +L  E+  + K
Sbjct: 3749 AGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGSPK 3792



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F    +D+ V  G      C+  G P P + W +  Q +R SR  +   D     SL 
Sbjct: 4309 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----SLW 4364

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 1854
            + +V   D   Y C A N LG AT  A L+V    +G
Sbjct: 4365 LENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG 4401



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
            E+VE + A   C     P P++ W+++DQ +       +     G   L I  V  ++  
Sbjct: 2761 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV---LQGGRVLQIPLVRAENAG 2817

Query: 1828 KYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
            +Y+CKA N +GE     EL+V T     G+ EE
Sbjct: 2818 RYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 2850



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 30/84 (35%), Positives = 40/84 (47%), Gaps = 6/84 (7%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ--IDYDEDGNCSLIISDVCGD 1824
            LE V G  A   C   G P P+V W K   S  E  H Q  +   E+G  SL ++ V   
Sbjct: 1216 LERVAGENASLPCPARGTPKPQVTWRKGPSS--EPLHGQPGVAVLEEG--SLFLASVSPA 1271

Query: 1825 DDAKYTCKAVNSLGEATCTAELIV 1848
            D   Y C+A N +G  +  A+L+V
Sbjct: 1272 DSGDYECQATNEVGSTSRRAKLVV 1295



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 60/271 (22%), Positives = 108/271 (39%), Gaps = 53/271 (19%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V E   + L C+    P   I W  +G  L T+  ++ ++ G    + + +A   D 
Sbjct: 1511 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDA 1568

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENT--------------KAPEMKSR-RPKSSL 1210
            G+Y C A N  G AE + ++ V   P  E                 A E  +R  P  +L
Sbjct: 1569 GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL 1628

Query: 1211 P------PVLGT-----ESDATVKKKPAP------------KTPPKAA---------MPP 1238
                   PV  +     E+D +V +  +P             +P   A         +PP
Sbjct: 1629 SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 1688

Query: 1239 QIIQFPEDQKVR--AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
            Q++      +V    G+ +EL  + +G+   T  W++  +  +E   ++V  +  G+ L 
Sbjct: 1689 QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQV--ASQGTTLH 1746

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            I     +H G +     N+ G+  A+V ++V
Sbjct: 1747 IDHVELDHSGLFACQATNEAGTAGAEVEVSV 1777



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            DV V  G  + L C+    P   + W  +G+ L +       ++G   S+ +E     D 
Sbjct: 3415 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL----EQGP--SLQLEAVGAGDS 3468

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
            G Y CVA ++AG+A    Q+TV + P  E++  P   S  P
Sbjct: 3469 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTP 3509



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            ++ V+E    +  C+  G P P + WFKD   +  S   ++ Y   G   L +      D
Sbjct: 1511 EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST--KVVYTRGGR-QLQLGRAQSSD 1567

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
               YTCKA N++G A     L V      EG G
Sbjct: 1568 AGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 1600



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            ++V++G  A   C + G+P P++ WFKD + +       I  D      L +        
Sbjct: 2455 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQANLSSA 2511

Query: 1827 AKYTCKAVNSLGEAT---CTAELIVETMEEGEGEGEEEE 1862
              Y+C A N++GE T     + L+  T+  G  +  +EE
Sbjct: 2512 GHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 2550



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V   + + L+CQ  + PP  + W  +G+ L+    + LS + +L  + +++A   D 
Sbjct: 2079 NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDA 2136

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP 1191
            G Y C A N AG +E    + V  AP
Sbjct: 2137 GHYTCEALNQAGHSEKHYNLNVWVAP 2162



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
            ++ +++V V     + LQC    +P  TI W  NG     +  + + ++G +  VS  + 
Sbjct: 2849 EELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 2908

Query: 1161 LPEDRGLYKCVAKNDAGQAE 1180
               D   Y CVA+N AG AE
Sbjct: 2909 --ADAASYMCVAENQAGSAE 2926



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 7/97 (7%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            D+ VV GS     C+  G P P V W KD + +       +    +   SL +  V   D
Sbjct: 3415 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL-------LSQSLEQGPSLQLEAVGAGD 3467

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
               Y+C AV+  GEA    +L V      E  G+  E
Sbjct: 3468 SGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTE 3504



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 54/230 (23%), Positives = 83/230 (36%), Gaps = 22/230 (9%)

Query: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVSIEKALPEDRGLYK 1169
            EG    L C  S  P  TI WT     L +      +S+EG+L    I +   +D G Y 
Sbjct: 989  EGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLL---IAQPSAQDAGAYV 1045

Query: 1170 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPK 1229
            C A N  G +    +++V+    S+     E     P  SL        D+   +  A  
Sbjct: 1046 CTATNTVGFSSQEMRLSVNRLALSKYVW--EEYGLLPSGSLRLAQVQVGDSGHYECTASN 1103

Query: 1230 TPPKAA--------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1281
                A+        +PPQ+   P   KV  GE+++L     G      +W K        
Sbjct: 1104 PAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSK-------- 1155

Query: 1282 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            + + ++       +   A R    G Y     N  G    +V L V++ P
Sbjct: 1156 DGVVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPP 1205



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 41/171 (23%), Positives = 68/171 (39%), Gaps = 26/171 (15%)

Query: 1689 MARRKWQKTG--------NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
            +  R W K G        +++RA G L     +   +GR S   + T+           D
Sbjct: 914  LPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAG------SQHRD 967

Query: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
            V     E V +  P + P  +  I +    EG  A   C   G P P + W K+  ++  
Sbjct: 968  V-----ELVVQVPPRIHPTATHHITN----EGVPASLPCVASGVPAPTITWTKETNAL-T 1017

Query: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
            SR    +  ++G  +L+I+     D   Y C A N++G ++    L V  +
Sbjct: 1018 SRGPHYNVSKEG--TLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNRL 1066



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 77/363 (21%), Positives = 129/363 (35%), Gaps = 71/363 (19%)

Query: 987  GKKKLPAENGSSSAETLNA-----KAVESS---KPLSNAQPSGPLKPV-GNAKPAETLKP 1037
            G+ +L +++G  + E LNA     K V+ S    P     P GP   V         L  
Sbjct: 2996 GRARL-SDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 3054

Query: 1038 MGNAKPAETL------KPMGNAKPDENLKSASKEELKKDVKND---VNCKRGHAGTTDNE 1088
              +A P  T+      +P+  A+  + L+   + E+++   +D    +CK  +       
Sbjct: 3055 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR 3114

Query: 1089 KRSESQGTAPAFKQ-KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI-IL 1146
              + +    P F+  K + V    G  L+L C VS  P  T+ W  +   ++++    ++
Sbjct: 3115 TFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV 3174

Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
            S+ G L    + +  P   G Y CVA+N   +A     V V  AP             R 
Sbjct: 3175 SRGGRL---QLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP-------------RI 3218

Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
            +SS                                    +  V  G+ V L  +  G  P
Sbjct: 3219 RSS--------------------------------GVAREHHVLEGQEVRLDCEADGQPP 3246

Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVN 1324
                W+K    + +     +    +G  L +   R    G YT +  N  G  +R   VN
Sbjct: 3247 PDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVN 3306

Query: 1325 LTV 1327
            + V
Sbjct: 3307 VLV 3309



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES--RHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            G + + DC + G P P++ W KD   +R S  RH      +  N SL I     DD  +Y
Sbjct: 4233 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH------QLQNGSLTIHRTERDDAGRY 4286

Query: 1830 TCKAVNSLGEATCTAELIVET 1850
             C A N +G A     L++++
Sbjct: 4287 QCLAENEMGVAKKVVILVLQS 4307



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 31/99 (31%), Positives = 42/99 (42%), Gaps = 13/99 (13%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD--------QSIRESRHFQIDYD 1809
            P  ++  RD+ V  G +A   C+  G P P V W + D         + R SR  Q D  
Sbjct: 786  PQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPD-- 843

Query: 1810 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               +  L    V  +D A Y C+A N  G+    A LIV
Sbjct: 844  ---SGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 879



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+   +P P + W KD      SR+ Q+     G   L I +   +D  +YTC   N LG
Sbjct: 2563 CEALAFPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELG 2619

Query: 1839 EA 1840
            EA
Sbjct: 2620 EA 2621



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            G  A   C+ +  P+P V W+KD Q +  ++  Q      G   L I +    D   Y+C
Sbjct: 3047 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA---LRGGQRLEIQEAQVSDKGLYSC 3103

Query: 1832 KAVNSLGEATCTAELIVE 1849
            K  N  GEA  T  L V+
Sbjct: 3104 KVSNVAGEAVRTFTLTVQ 3121



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)

Query: 1766 DLEVVEG---SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
            DLE V     S+    C +  +P+PEV W+KD Q++         +   G  +L +    
Sbjct: 2943 DLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGTHTLQLGRAR 2999

Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   YTC+A+N+ G      +L V
Sbjct: 3000 LSDSGMYTCEALNAAGRDQKLVQLSV 3025



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 53/243 (21%)

Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
            +  E++G    +++      + E     L C  ++ PP  + W    + L     + + Q
Sbjct: 2748 REEEARGGVTEYRE------IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 2801

Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
             G +  + + +A  E+ G Y C A N+ G+     ++ V                     
Sbjct: 2802 GGRVLQIPLVRA--ENAGRYSCKASNEVGEDWLHYELLV--------------------- 2838

Query: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268
              PPV+  +++  V                      E+  V A  +V L     G    T
Sbjct: 2839 LTPPVILGDTEELV----------------------EEVTVNASSTVSLQCPALGNPVPT 2876

Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
             +W++       S  ++V   E+G  L +  A       Y  + EN+ GS +    L V 
Sbjct: 2877 ISWLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 2934

Query: 1329 DKP 1331
              P
Sbjct: 2935 VPP 2937



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
            C   ++  +D + R       PA      ++ +      LL C+ S  P   ++W  +G+
Sbjct: 3743 CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQ 3802

Query: 1137 TLKTTKFIILSQEGSLCSVSIEKAL-----PEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
             L         Q+G+   +     L     P+D   ++CV  N+ G+A    QVTV   P
Sbjct: 3803 KLD-----FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPP 3857



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/278 (23%), Positives = 93/278 (33%), Gaps = 49/278 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVS 1156
            P       D  V     ++L C  +  P  T+ W+  G  L        +S  G+L    
Sbjct: 3857 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL---E 3913

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP------------ASENTKAPEMKSR 1204
            I +ALP   G Y C A+N AG A     +TV  +P            A E    P   S 
Sbjct: 3914 IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG 3973

Query: 1205 RP-------KSSLPPVLGTESDA--------------------TVKKKPA----PKTPPK 1233
             P       K  L    G  +                       + K  A     KT   
Sbjct: 3974 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLV 4033

Query: 1234 AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
              +PP I     D     G    L  K  G+     TW K  + +  +E  K     +G 
Sbjct: 4034 VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEG-KFTIQPSG- 4091

Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +L +     +  G YT   EN +G  + +V+LT++  P
Sbjct: 4092 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 4129



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCGDDD 1826
            V  G  A   C+  G P P V+W++           ++    +G+ S  L I      D 
Sbjct: 709  VAVGEEAVLVCEASGVPPPRVIWYRGG--------LEMILAPEGSSSGKLRIPAAQERDA 760

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
              YTC+AVN LG+A+   +L V
Sbjct: 761  GTYTCRAVNELGDASAEIQLAV 782



 Score = 38.5 bits (88), Expect = 0.062
 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 15/157 (9%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            ++V V     + L C+  + P   I W  +G   + ++ I L        + I  A  ED
Sbjct: 2549 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKED 2606

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA-SENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             G Y CV  N+ G+A  +  V V   P+ S++    E+  +  K+ +   L  E ++   
Sbjct: 2607 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESW-- 2664

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
                      A  PP I  + + Q V     +++ G+
Sbjct: 2665 ----------AVPPPTIRWYKDGQPVTPSSRLQVLGE 2691



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 12/103 (11%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIR-----ESRHFQIDYDE-------DGNCSLIIS 1819
            G +   +C   G+P PE+VW KD Q +          + + + +       D   SL   
Sbjct: 1315 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 1374

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
             +   D   Y+C+A N  G A     L+V T     G G  +E
Sbjct: 1375 RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQE 1417



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 33/132 (25%), Positives = 50/132 (37%), Gaps = 12/132 (9%)

Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
            V  G+ L L C    +P   + W+ +G        ++L   G   SV        D G Y
Sbjct: 1131 VLVGEALDLNCVAEGNPEPQLSWSKDG--------VVLQGRGPQGSVHFAAIRTSDAGRY 1182

Query: 1169 KCVAKNDAGQAECSCQVTVDDAP--ASENTKAPEMKSRRPKSSLP-PVLGTESDATVKKK 1225
            +C A N AG      ++ V + P   ++ T     +     +SLP P  GT       +K
Sbjct: 1183 RCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRK 1242

Query: 1226 PAPKTPPKAAMP 1237
              P + P    P
Sbjct: 1243 -GPSSEPLHGQP 1253



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 45/250 (18%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            GD    A +    TS++    RV+   +   P     P  + +    TA    +  G P 
Sbjct: 3648 GDYSCTARNAAGSTSVAF---RVE---IHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA 3701

Query: 62   PQVTWHRNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            P V+W ++  P+     RF     I    SL I  V  +D G Y C A+N +G+ +   +
Sbjct: 3702 PLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 3757

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            L V                       PA+   PS               + +        
Sbjct: 3758 LRV--------------------LEPPAIAPSPS--------------NLTLTAHTPALL 3783

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             C+ +G P+P V W K    L    +           L +      D   + C+V N  G
Sbjct: 3784 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 3843

Query: 241  KASMSAELSI 250
            +A    ++++
Sbjct: 3844 EAHRLYQVTV 3853



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P  + +  +L +   + A   C+  G P P VVW+KD Q + + R  Q  Y    + +L+
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL-DFRLQQGAYRLLPSNALL 3822

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEA 1840
            ++     D A++ C   N +GEA
Sbjct: 3823 LTAPGPQDSAQFECVVSNEVGEA 3845



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 32/132 (24%), Positives = 53/132 (40%), Gaps = 13/132 (9%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F     D  +  G +L L+C     P   I WT+N + +       +S++    ++  
Sbjct: 4129 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 4184

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT- 1216
                 ED G Y C A+N  G+ +    V V +AP  +      +        + PV G+ 
Sbjct: 4185 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYL--------VEPVGGSI 4236

Query: 1217 ESDATVKKKPAP 1228
            + D  V+  P P
Sbjct: 4237 QLDCVVRGDPVP 4248



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 26/93 (27%), Positives = 39/93 (41%), Gaps = 9/93 (9%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P      R L+V+ G A   +C  EG P+P++ W KD   ++               S
Sbjct: 1118 VPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQ---------GRGPQGS 1168

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            +  + +   D  +Y C+A NS G      EL V
Sbjct: 1169 VHFAAIRTSDAGRYRCEASNSAGVDAWEVELRV 1201



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 8/149 (5%)

Query: 1694 WQKTG---NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
            W K G    A R I  L     +  L+ +K   G  T  +  E  E+ ++     L   +
Sbjct: 2575 WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 2634

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
              K    P     +++++    S    +C+    P P + W+KD Q +  S   Q+  + 
Sbjct: 2635 ISKDD--PLGEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE- 2691

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
                 L I      D  +Y C A N  GE
Sbjct: 2692 --GRLLQIQPTQVSDSGRYLCVATNVAGE 2718



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 8/105 (7%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K G        L S ++  G S +  + G+  S   +    SE   ++   +    E 
Sbjct: 3440 WMKDGEP------LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 3493

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1798
            PH++     T  +L +  G+     C  +G P P + W KD Q++
Sbjct: 3494 PHIEDSGQPT--ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL 3536



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 4/92 (4%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            G+     C   G P P+V W KD Q +     H Q+   EDG    I     G D+ +Y 
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV--QEDGQVLRITGSHVG-DEGRYQ 1479

Query: 1831 CKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
            C A +  G+     +L V       G  E  E
Sbjct: 1480 CVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 1511



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            + VV+   A  +C   G P P V W +D Q +      Q+   ++   SL +        
Sbjct: 2268 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQL---QNQGQSLHVERAQAAHT 2324

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
             +Y+C A N  G A    EL V
Sbjct: 2325 GRYSCVAENLAGRAERKFELSV 2346



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1778 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1837
            +C +E  P P++ W +D   ++E  H Q  + E G   L +  +   D   Y+C A N+ 
Sbjct: 3602 ECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGR-FLQLQALSTADSGDYSCTARNAA 3658

Query: 1838 GEATCTAELIVETM 1851
            G  +    + + T+
Sbjct: 3659 GSTSVAFRVEIHTV 3672



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P F+    D  +  G      C   G P P + W  +D+ + E        ++DG  +
Sbjct: 4127 VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGST 4181

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
            L  + V  +D   Y C A N +G     + + V+     +GE
Sbjct: 4182 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 4223



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+  +  R  C   G P P ++W KD   +  +    +     G   L ++     D  +
Sbjct: 1989 VLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-LTLASARASDSGR 2047

Query: 1829 YTCKAVNSLGE 1839
            Y+C AV+++GE
Sbjct: 2048 YSCVAVSAVGE 2058



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 19/153 (12%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K GN V            +G  G +   G     L + +       S   + AV E++
Sbjct: 2011 WLKDGNPVSP----------AGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 2060

Query: 1754 P------HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
                   H+ P       ++ VV   +   +C+    P P + W+KD + +       + 
Sbjct: 2061 QDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS 2120

Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
             D+     L +      D   YTC+A+N  G +
Sbjct: 2121 ADK---ALLQVDRADVWDAGHYTCEALNQAGHS 2150



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 1236 MPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
            +PPQI    + P    V       L    TG  P T TW +  + +     ++++N   G
Sbjct: 2254 VPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQ--G 2311

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
              L +  A+  H G Y+ + EN  G  + +  L+V+  P+
Sbjct: 2312 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPE 2351



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 15/124 (12%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            ++ +  G  + L C     P   I W  +G+ L  T+    S+   +  V        D 
Sbjct: 3504 ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--TRLENNSRATRVLRV-------RDA 3554

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            GLY C+A++ AG  E S +V V   P     + P          L  VL    + +V+ +
Sbjct: 3555 GLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL--VL----ECSVEAE 3608

Query: 1226 PAPK 1229
            PAPK
Sbjct: 3609 PAPK 3612



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+E ++   +C   G P P+V WFK  Q +  S    +    DG   L I      D   
Sbjct: 1897 VLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRV-LRIEQAQLSDAGS 1953

Query: 1829 YTCKAVNSLG 1838
            Y C A N  G
Sbjct: 1954 YRCVASNVAG 1963



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 59/265 (22%), Positives = 90/265 (33%), Gaps = 65/265 (24%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPE 1163
            Q+V    G  + LQC  S  P   + WT + +  L     + + ++G +  ++       
Sbjct: 1416 QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--G 1473

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y+CVA + AGQ     Q+ V  AP                   P + G+     V 
Sbjct: 1474 DEGRYQCVAFSPAGQQARDFQLRV-HAP-------------------PTIWGSNETGEV- 1512

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                      A M   ++Q              L  +  G      TW K    +  S  
Sbjct: 1513 ----------AVMEDHLVQ--------------LLCEARGVPTPNITWFKDGALLPTS-- 1546

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------------ 1331
             KV  +  G +L +  A+    G YT    N +G+ +    L V   P            
Sbjct: 1547 TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV 1606

Query: 1332 DPPAGTPCASDIRS---SSLTLSWY 1353
               AG P A +  +    S TLSW+
Sbjct: 1607 KAVAGRPVALECVARGHPSPTLSWH 1631



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+  G P P + WF+ ++ +      +  Y   G   L ++     D   Y+C A N  G
Sbjct: 2374 CEAMGIPPPAIRWFRGEEPVSPG---EDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 2430

Query: 1839 EATCTAELIVETMEEGEGEGEEEEE 1863
            EA       VE +     E E+ EE
Sbjct: 2431 EA--RRNFSVEVLVPPSIENEDLEE 2453



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            H  P        + V     A   C+ +G P P V W KD   + + R  + +   +G  
Sbjct: 3670 HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL-DPRSPRFEILPEG-- 3726

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
            SL I  V   D   Y C A NS G
Sbjct: 3727 SLRIQPVLAQDAGHYLCLASNSAG 3750



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 12/101 (11%)

Query: 1751 EEKPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY 1808
            +  P VKP  S  + + + EV+        C+  G P P + W K+  ++      Q+  
Sbjct: 3945 QASPVVKPLPSVVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVL- 3997

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                   L I+    +D   Y C A NS G A     L+V+
Sbjct: 3998 ---PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 4035



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTL--NGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1169
            G+   L C     P   + W    + + L     + + +EGSL   S+    P D G Y+
Sbjct: 1221 GENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVS---PADSGDYE 1277

Query: 1170 CVAKNDAGQAECSCQVTVDDAPA 1192
            C A N+ G      ++ V   P+
Sbjct: 1278 CQATNEVGSTSRRAKLVVYVPPS 1300



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%)

Query: 1719 RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 1778
            R  S G  +S L +    +     +A L+   E +   +   ++ +  +  + G      
Sbjct: 1653 RLESPGEASSGLYS--CVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELP 1710

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+  G P P + W ++ +   E    Q+        +L I  V  D    + C+A N  G
Sbjct: 1711 CQASGSPVPTIQWLQNGRPAEELAGVQV---ASQGTTLHIDHVELDHSGLFACQATNEAG 1767

Query: 1839 EATCTAELIV 1848
             A    E+ V
Sbjct: 1768 TAGAEVEVSV 1777



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 3/71 (4%)

Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            V GS     C + G P P V W KD   +  S    +     G   L +S +       Y
Sbjct: 3137 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTY 3193

Query: 1830 TCKAVNSLGEA 1840
            TC A N+  EA
Sbjct: 3194 TCVAENTQAEA 3204



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 23/85 (27%), Positives = 33/85 (38%), Gaps = 3/85 (3%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            +H    + LL+ C V S  P  +        L   +     QE    S  I +A   + G
Sbjct: 436  IHGYLHQPLLVSCSVHSALPFRLQLRRGEARLGEERHF---QESGNSSWEILRASKAEEG 492

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAP 1191
             Y+C A + AG      Q+ V D P
Sbjct: 493  TYECTAVSRAGTGRAKAQIVVTDPP 517



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-D 1825
            ++ V G     +C   G+P P + W  +   + ES   +++ D     S++  +  G+  
Sbjct: 1606 VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG----SVLRLESPGEAS 1661

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEE---GEGEGE 1859
               Y+C A +  GEA     + V+   +    EG G+
Sbjct: 1662 SGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ 1698



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 1/93 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            L V EG      C+  G P P++ W KD Q +       + +       L +       +
Sbjct: 2172 LTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQE 2230

Query: 1827 AKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
              YTC+  N +G ++   +L V    +  G  E
Sbjct: 2231 GTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 2263


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score =  171 bits (434), Expect = 5e-42
 Identities = 181/790 (22%), Positives = 294/790 (37%), Gaps = 114/790 (14%)

Query: 39   PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
            P  L +  GA  +     +G P+P +TWH++GQ +T      L+   R T  L +     
Sbjct: 2220 PTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR-----LENNSRATRVLRVR---- 2270

Query: 99   EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
             D G YTC A + +GA                     + K+   R  AP     P+I G 
Sbjct: 2271 -DAGLYTCLAESPAGA---------------------IEKSFRVRVQAP-----PNIVGP 2303

Query: 159  CPPKFATKL--GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
              P+F   L  G++V++        C +   P P++TW +  + LQ  A     E+   +
Sbjct: 2304 RGPRFVVGLAPGQLVLE--------CSVEAEPAPKITWHRDGIVLQEDAHTQFPERG--R 2353

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-----------SANRSFVRETK 265
             L++  ++  D G Y+C   N +G  S++  + I  +            S N++ +   +
Sbjct: 2354 FLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQ 2413

Query: 266  ATNSDV-----RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES 320
            A          RK+   +  +  + + L   +        Q  G     A++     R+ 
Sbjct: 2414 ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQG 2473

Query: 321  KLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR--------APGLGVLSPSGEERK 372
            +     + P  AP    L  T+ +  L        P+           L      G  R 
Sbjct: 2474 RDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRL 2533

Query: 373  RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
             P+     T P  Q     + VVS        +        P          V     V 
Sbjct: 2534 LPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVV 2593

Query: 433  FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
              C  +GIP P V+W   G  +  +      Y  + S  L + +A    +G Y+C+A N+
Sbjct: 2594 LTCHSTGIPAPTVSWSKAGAQLGARGSG---YRVSPSGALEIGQALPIHAGRYTCSARNS 2650

Query: 493  QGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
             G       L V+   V++  PS    + +      ++ +L C   G P P ITW   G 
Sbjct: 2651 AGVAHKHVFLTVQASPVVKPLPSVVRAVAE------EEVLLPCEASGIPRPTITWQKEGL 2704

Query: 553  PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 612
             +    ST      +L I  A PED G Y C+A+N+ G       + V            
Sbjct: 2705 NVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ----------- 2753

Query: 613  LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHF 671
                      P+   GL DL   +GS   +  +  G+P P + W  +G  +  +E  F  
Sbjct: 2754 --------VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTI 2805

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 731
            +  G    L ++ +  +D GTYTC A N+ G  R +  LT+        P F + P   +
Sbjct: 2806 QPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRS 2857

Query: 732  ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 791
              LG  + + CA  G P P + W  + + + +      V + +   TL    V    +G 
Sbjct: 2858 LRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG-----VSEQDGGSTLQRAAVSREDSGT 2912

Query: 792  YEILLKNRVG 801
            Y    +NRVG
Sbjct: 2913 YVCWAENRVG 2922



 Score =  170 bits (430), Expect = 1e-41
 Identities = 202/801 (25%), Positives = 298/801 (37%), Gaps = 150/801 (18%)

Query: 19   VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
            + PS     PL E        + +  K  +T   E      P P + W+++GQP+T   R
Sbjct: 1349 IPPSISKDDPLAEVGV-----KEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSR 1403

Query: 79   FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
              +   +     L I      D G+Y C ATN +G       + ++         P + +
Sbjct: 1404 LQV---LGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQ--------VPPMFQ 1452

Query: 139  TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
             +GD  +A  + +R     E      T+   +V  E       C     P P +TW + +
Sbjct: 1453 KVGDFSAAFEILSRE----EEARGGVTEYREIV--ENNPAYLYCDTNAIPPPDLTWYRED 1506

Query: 199  VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258
             PL     VSV +  G +VL+I  V  ++ G Y+C   N  G+  +  EL          
Sbjct: 1507 QPLSAGDEVSVLQ--GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYEL---------- 1554

Query: 259  SFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP---WAANSQPQ 315
              V        D  + V  V    S   SL+          P  G   P   W  N  P 
Sbjct: 1555 -LVLTPPVILGDTEELVEEVTVNASSTVSLQC---------PALGNPVPTISWLQNGLPF 1604

Query: 316  PPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375
             P                 +P LQ       LQ +  +    A  + V        ++  
Sbjct: 1605 SP-----------------SPRLQVLEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLF 1647

Query: 376  PPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC 435
              R    P R  GL  + V +                               N +V   C
Sbjct: 1648 TLR-VQVPPRIAGLDLEQVTAIL-----------------------------NSSVSLPC 1677

Query: 436  EVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQ 495
            +V   P PEV W+ +   +   E   EV+   G+H L L +AR  DSG Y+C A NA G+
Sbjct: 1678 DVHAHPNPEVTWYKDSQALSLGE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGR 1734

Query: 496  LSCSWTLQVERLAVMEVAPSFSSVLK---DCAVIE-GQDFVLQCSVRGTPVPRITWLLNG 551
                   ++ +L+V+ V P+F    +   D  ++  G   VL C     P P +TW  +G
Sbjct: 1735 -----DQKLVQLSVL-VPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDG 1788

Query: 552  QPIQYA-RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
            QP+  A R+    G   L IQ+A   D G Y+C   N  G+   +  +TV          
Sbjct: 1789 QPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ--------- 1839

Query: 611  YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 670
              +P     P      Q       + GS + +T  VSG P P V WL +   ++ S    
Sbjct: 1840 --VPPTFENPKTETVSQ-------VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHG 1890

Query: 671  FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV 730
               RG +  L +  + P   GTYTC A N+  E R   V+ V           +  PR  
Sbjct: 1891 VVSRGGR--LQLSRLQPAQAGTYTCVAENTQAEARKDFVVAV-----------LVAPRIR 1937

Query: 731  TASL--------GQSVLISCAIAGDPFPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVL 781
            ++ +        GQ V + C   G P P V WL+DG  L +D G H       D  +LVL
Sbjct: 1938 SSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYL--DGGSLVL 1995

Query: 782  KKVQPWHAGQYEILLKNRVGE 802
            K ++   AG Y  +  N  GE
Sbjct: 1996 KGLRASDAGAYTCVAHNPAGE 2016



 Score =  148 bits (374), Expect = 4e-35
 Identities = 110/380 (28%), Positives = 176/380 (46%), Gaps = 44/380 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C+  G P+P + W  +G PV   EG   +     S  L +     +D+GTY+CTA NA G
Sbjct: 2777 CKARGSPEPNITWDKDGQPVSGAEGKFTIQP---SGELLVKNLEGQDAGTYTCTAENAVG 2833

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
            +      L +       V P F+++  D ++  G    L+C+ RG+P PRI W +N +P+
Sbjct: 2834 RARRRVHLTIL------VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPV 2887

Query: 555  QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP 614
                S  + G + L       ED GTY C AEN +G+    ++V V E            
Sbjct: 2888 TEGVSEQDGG-STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKE------------ 2934

Query: 615  VAPSKPTAPIFLQG--LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 672
                   AP+ LQG   S L    G  + +   V G+P P++ W+ +G  ++ S   H  
Sbjct: 2935 -------APV-LQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQL 2986

Query: 673  QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 732
            Q G   SL I+    +D G Y C A N  G  +   +L +Q     + P F  +P+ +T 
Sbjct: 2987 QNG---SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQ-----SAPVFQVEPQDMTV 3038

Query: 733  SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
              G  V + C   G+P PT+ WL+ G+ L + +     L +    +L L+ V+   AG Y
Sbjct: 3039 RSGDDVALRCQATGEPTPTIEWLQAGQPL-RASRRLRTLPDG---SLWLENVETGDAGTY 3094

Query: 793  EILLKNRVGECSCQVSLMLQ 812
            + +  N +G  + +  L+++
Sbjct: 3095 DCVAHNLLGSATARAFLVVR 3114



 Score =  146 bits (369), Expect = 2e-34
 Identities = 120/405 (29%), Positives = 179/405 (44%), Gaps = 44/405 (10%)

Query: 412  AFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            A P  +  P        + V   CE SGIP+P + W  EG  V     +    +      
Sbjct: 2664 ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVST----QVLPGGQ 2719

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L +  A   D+G Y C A N+ G       L      V++V P   + L D +  EG   
Sbjct: 2720 LRIAHASPEDAGNYLCIAKNSAGSAMGKTRL------VVQVPPVIENGLPDLSTTEGSHA 2773

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA-ELHIQDALPEDHGTYTCLAENALG 590
             L C  RG+P P ITW  +GQP+  A        + EL +++   +D GTYTC AENA+G
Sbjct: 2774 FLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVG 2833

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
            +      +T+           +LPV  + P          D  +  G ++ +     G+P
Sbjct: 2834 RARRRVHLTI----------LVLPVFTTLP---------GDRSLRLGDRLWLRCAARGSP 2874

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
             P + W  N   + E      EQ G   +L    V  ED+GTY C A N  G  RTQAV 
Sbjct: 2875 TPRIGWTVNDRPVTEGVS---EQDGGS-TLQRAAVSREDSGTYVCWAENRVG--RTQAVS 2928

Query: 711  TVQEPHDGTQPWFISKPRS-VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
             V   H    P    +  S +   +G S+ + C + GDP P +HW++DG  L + +    
Sbjct: 2929 FV---HVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPL-RGSHLRH 2984

Query: 770  VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNS 814
             LQN    +L +++ +   AG+Y+ L +N +G     V L+LQ++
Sbjct: 2985 QLQNG---SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSA 3026



 Score =  138 bits (348), Expect = 4e-32
 Identities = 185/745 (24%), Positives = 274/745 (36%), Gaps = 117/745 (15%)

Query: 31   EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCG---IRG 87
            E PA    P NL +     A       G P+P V W ++GQ +     F L  G   +  
Sbjct: 2480 EPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLD----FRLQQGAYRLLP 2535

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
            + +L++ A   +D  ++ C  +N  G      ++TV                        
Sbjct: 2536 SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH----------------------- 2572

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
                 P+I  +      T +  VV+        +C  TG P P V+W K    L   AR 
Sbjct: 2573 ---VPPTIADDQTDFTVTMMAPVVL--------TCHSTGIPAPTVSWSKAGAQL--GARG 2619

Query: 208  SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------LDSANRSFV 261
            S    +    LEI        G YTC   N +G A     L++Q       L S  R+  
Sbjct: 2620 SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVA 2679

Query: 262  RETKATNSDV----------RKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
             E      +           +KE  NV +  S         +  + S    G     A N
Sbjct: 2680 EEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKN 2739

Query: 312  SQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA--ARVQPEPR------------ 357
            S      +++L   +  P      P L  T  S       AR  PEP             
Sbjct: 2740 SAGSAMGKTRLV-VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 2798

Query: 358  APGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFE 417
            A G   + PSGE   +    + A   T      +++ V +A  RR+ +        P F 
Sbjct: 2799 AEGKFTIQPSGELLVKNLEGQDAGTYT----CTAENAVGRA-RRRVHLT---ILVLPVFT 2850

Query: 418  SKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKA 477
            + P  + ++    +  RC   G P P + W +   PV   EG   V E  G   L     
Sbjct: 2851 TLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVT--EG---VSEQDGGSTLQRAAV 2905

Query: 478  RTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSV 537
               DSGTY C A N  G+      + V+   V++   +FS +++      G    L C V
Sbjct: 2906 SREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQ-GEAFSYLVEPV----GGSIQLDCVV 2960

Query: 538  RGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
            RG PVP I W+ +G P++ +    +     L I+    +D G Y CLAEN +G       
Sbjct: 2961 RGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRYQCLAENEMGVA----- 3015

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
                      K   +L +     +AP+F     D+ V  G  V +  Q +G P P + WL
Sbjct: 3016 ----------KKVVILVL----QSAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWL 3061

Query: 658  HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPH 716
              G  ++ S        G   SL ++ V   D GTY C A N  G    +A L V+ EP 
Sbjct: 3062 QAGQPLRASRRLRTLPDG---SLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118

Query: 717  D--GTQPWFISKPRSVTASLGQSVL 739
               G+    I+  +   A+L  SV+
Sbjct: 3119 GSWGSMTGVINGRKFGVATLNTSVM 3143



 Score =  133 bits (335), Expect = 1e-30
 Identities = 186/829 (22%), Positives = 285/829 (34%), Gaps = 196/829 (23%)

Query: 58   GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
            G P P + W +NG+P        +    +GT +L I  V  +  G + C+ATN +G    
Sbjct: 433  GSPVPTIQWLQNGRPAEELAG--VQVASQGT-TLHIDHVELDHSGLFACQATNEAGTAGA 489

Query: 118  TVELTVEGSFAK-----QLGQ----------------PVVSKTLGDRFSAPAVE---TRP 153
             VE++V G +A       +GQ                P V +  G     P VE   +  
Sbjct: 490  EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPG 549

Query: 154  SIWGE-----------------------------------------------CPPKFATK 166
            S+WGE                                                PP     
Sbjct: 550  SLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPG 609

Query: 167  LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
                 V E       C  +G P P V+W KG+ P+     V+VS     +VL I      
Sbjct: 610  PVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLS 667

Query: 227  DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLD 286
            D G Y C+  N +G   +   L +                          NV  + +   
Sbjct: 668  DAGSYRCVASNVAGSTELRYGLRV--------------------------NVPPRITLPP 701

Query: 287  SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSS-- 344
            SL           P    +P     +    P  + +     +P +   TP LQ       
Sbjct: 702  SL---------PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV 752

Query: 345  ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPG--LGSQDVVSKAANRR 402
            +TL +AR     R   + V S  GE+R      +        P   LG +  VS  AN  
Sbjct: 753  LTLASARASDSGRYSCVAV-SAVGEDR------QDVVLQVHMPPSILGEELNVSVVANES 805

Query: 403  IPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIE 462
            + +E Q  +                            +P P ++W+ +G P+  + G   
Sbjct: 806  VALECQSHA----------------------------MPPPVLSWWKDGRPLEPRPG--- 834

Query: 463  VYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKD 522
            V+  A    L + +A   D+G Y+C A N  G     + L V    V  +  S +  ++ 
Sbjct: 835  VHLSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVR- 893

Query: 523  CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHG 579
                EG    L C  RG P P+I+W  +GQP+    +  +   A    L++  A     G
Sbjct: 894  ----EGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 949

Query: 580  TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 639
            TYTC   N +G  S    + VH           +P   + P  P      + + V+    
Sbjct: 950  TYTCECSNVVGNSSQDLQLEVH-----------VPPQIAGPREP-----PTQVSVVQDGV 993

Query: 640  VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 699
             T+    +G PPP V W  +G  +        + +G   SL ++      TG Y+C A N
Sbjct: 994  ATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQG--QSLHVERAQAAHTGRYSCVAEN 1051

Query: 700  SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 759
             AG    +  L+V  P +      +    ++TA+L   + + C   G P P + W R   
Sbjct: 1052 LAGRAERKFELSVLVPPELIGD--LDPLTNITAALHSPLTLLCEAMGIPPPAIRWFR--- 1106

Query: 760  ALCKDTGHFEVLQNEDVFTLV------LKKVQPWHAGQYEILLKNRVGE 802
                  G   V   ED + L       + + Q   +G Y  L  N  GE
Sbjct: 1107 ------GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGE 1149



 Score =  128 bits (322), Expect = 5e-29
 Identities = 110/377 (29%), Positives = 156/377 (41%), Gaps = 44/377 (11%)

Query: 425  VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
            V     V+  CE  G+P P V+W  +G P+  Q       E   S  L L      DSGT
Sbjct: 2136 VVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQS-----LEQGPS--LQLEAVGAGDSGT 2188

Query: 485  YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
            YSC A +  G+    + L V     +E     S    + ++  G    L C  +GTP P 
Sbjct: 2189 YSCVAVSEAGEARRHFQLTVMEPPHIED----SGQPTELSLTPGAPMELLCDAQGTPQPN 2244

Query: 545  ITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 604
            ITW  +GQ +    +   A    L ++DA     G YTCLAE+  G +  S  V V    
Sbjct: 2245 ITWHKDGQALTRLENNSRA-TRVLRVRDA-----GLYTCLAESPAGAIEKSFRVRVQA-- 2296

Query: 605  SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 664
                     P     P  P F+ GL+        Q+ +   V   P P++ W  +G  +Q
Sbjct: 2297 ---------PPNIVGPRGPRFVVGLAP------GQLVLECSVEAEPAPKITWHRDGIVLQ 2341

Query: 665  ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 724
            E     F +RG    L +Q +   D+G Y+C A N+AG       + +      T P   
Sbjct: 2342 EDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-----TVPTIR 2394

Query: 725  SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 784
            S P +V  S+ Q+ L+ C   G P P V W +D   L   +  FE+L      +L ++ V
Sbjct: 2395 SGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPV 2451

Query: 785  QPWHAGQYEILLKNRVG 801
                AG Y  L  N  G
Sbjct: 2452 LAQDAGHYLCLASNSAG 2468



 Score =  128 bits (321), Expect = 6e-29
 Identities = 116/443 (26%), Positives = 177/443 (39%), Gaps = 43/443 (9%)

Query: 431 VKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTAS 490
           V+ +C  SG+P P+V W  +  PV      ++V ED     L +  +   D G Y C A 
Sbjct: 144 VELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDG--QVLRITGSHVGDEGRYQCVAF 201

Query: 491 NAQGQLSCSWTLQVERLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 548
           +  GQ +  + L+V         P+   S+   + AV+E     L C  RG P P ITW 
Sbjct: 202 SPAGQQARDFQLRVH------APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWF 255

Query: 549 LNGQPIQYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSR 607
            +G  +  +       G  +L +  A   D G YTC A NA+G            +K++R
Sbjct: 256 KDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAA----------EKATR 305

Query: 608 KSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE 667
              Y+ P        P  +      K + G  V +     G+P P + W H G  + ES 
Sbjct: 306 LDVYVPPTIEGAGGRPYVV------KAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN 359

Query: 668 DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 727
           +   E  G+   L ++      +G Y+C A + AGE   Q  + VQ P    Q       
Sbjct: 360 ESRLETDGSV--LRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVP---PQLLVAEGL 414

Query: 728 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 787
             VT  +GQ + + C  +G P PT+ WL++G+   +  G     Q     TL +  V+  
Sbjct: 415 GQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT---TLHIDHVELD 471

Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARA---LPRGREPASCEDLCGGGVGAD----- 839
           H+G +     N  G    +V + +    A     +P G+     E         D     
Sbjct: 472 HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 531

Query: 840 GGGSDRYGSLRPGWPARGQGWLE 862
           G G+     L  GW + G  W E
Sbjct: 532 GWGAHPKPPLVEGWCSPGSLWGE 554



 Score =  127 bits (318), Expect = 1e-28
 Identities = 105/399 (26%), Positives = 167/399 (41%), Gaps = 47/399 (11%)

Query: 413  FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
            FP  ES   +  V+E    +  CE  G+P P+++W  +G P+  +   ++ +  A    L
Sbjct: 882  FPLRES--HTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVSAVGRLL 938

Query: 473  CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE---RLAVMEVAPSFSSVLKDCAVIEGQ 529
             L +A+    GTY+C  SN  G  S    L+V    ++A     P+  SV++D       
Sbjct: 939  YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVVQDGVA---- 994

Query: 530  DFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV------AELHIQDALPEDHGTYTC 583
               L+C+  G P P +TW  +GQP+       E G+        LH++ A     G Y+C
Sbjct: 995  --TLECNATGKPPPTVTWERDGQPV-----GAELGLQLQNQGQSLHVERAQAAHTGRYSC 1047

Query: 584  LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 643
            +AEN  G             ++ RK E  + V P        L  L+++     S +T+ 
Sbjct: 1048 VAENLAG-------------RAERKFELSVLVPPELIGD---LDPLTNITAALHSPLTLL 1091

Query: 644  VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 703
             +  G PPP + W      +   ED +    G    L + +   +D+G Y+C A N AGE
Sbjct: 1092 CEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWM--LKMTQTQEQDSGLYSCLASNEAGE 1149

Query: 704  VRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 763
             R    + V  P              +    GQ+  + C + G P P + W +DG+ L +
Sbjct: 1150 ARRNFSVEVLVPPSIENE---DLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLAR 1206

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
               H     + D   L + +     AG Y  +  N VGE
Sbjct: 1207 GDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGE 1242



 Score =  124 bits (311), Expect = 9e-28
 Identities = 113/433 (26%), Positives = 165/433 (38%), Gaps = 53/433 (12%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
           P  E  P ++ V EN +V   C  SG+P P+V+WF    PV    G   V        L 
Sbjct: 604 PNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTVSVDGRVLR 660

Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
           + +A+  D+G+Y C ASN  G     + L+V     + + PS         V+      L
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPG-----PVLVNTPVRL 715

Query: 534 QCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
            C+  G P P + WL +G P+  A +       G   L +  A   D G Y+C+A +A+G
Sbjct: 716 TCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVG 775

Query: 591 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
           +      + VH                     P  L    ++ V+    V +  Q    P
Sbjct: 776 EDRQDVVLQVH-------------------MPPSILGEELNVSVVANESVALECQSHAMP 816

Query: 651 PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVL 710
           PP + W  +G  ++     H      +  L +      D G YTCEA N AG        
Sbjct: 817 PPVLSWWKDGRPLEPRPGVHLS--ADKALLQVDRADVWDAGHYTCEALNQAGH------- 867

Query: 711 TVQEPHDGTQPWF-----ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 765
              E H     W      + +  ++T   G    +SC   G PFP + W +DG+ L    
Sbjct: 868 --SEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPL---P 922

Query: 766 GHFEVLQNEDVF--TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR 823
           G    LQ+       L L + Q    G Y     N VG  S  + L +      A P  R
Sbjct: 923 GEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGP--R 980

Query: 824 EPASCEDLCGGGV 836
           EP +   +   GV
Sbjct: 981 EPPTQVSVVQDGV 993



 Score =  119 bits (298), Expect = 3e-26
 Identities = 109/396 (27%), Positives = 163/396 (41%), Gaps = 40/396 (10%)

Query: 423  QEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDS 482
            +E+ EN      C+ + IP P++ W+ E  P+   +   EV    G   L +   R  ++
Sbjct: 1478 REIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGD---EVSVLQGGRVLQIPLVRAENA 1534

Query: 483  GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
            G YSC ASN  G+    + L V  L    +      ++++  V       LQC   G PV
Sbjct: 1535 GRYSCKASNEVGEDWLHYELLV--LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPV 1592

Query: 543  PRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
            P I+WL NG P   +      E G   L +  A   D  +Y C+AEN  G          
Sbjct: 1593 PTISWLQNGLPFSPSPRLQVLEDGQV-LQVSTAEVADAASYMCVAENQAG---------- 1641

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                    +E L  +    P     L  L  +  +  S V++   V  +P PEV W  + 
Sbjct: 1642 -------SAEKLFTLRVQVPPRIAGLD-LEQVTAILNSSVSLPCDVHAHPNPEVTWYKDS 1693

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
              +   E+  F   GT H+L +      D+G YTCEA N+AG  +    L+V  P     
Sbjct: 1694 QALSLGEEV-FLLPGT-HTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVP----- 1746

Query: 721  PWFISKPR----SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 776
            P F   PR    +V   +G   ++SC     P PTV W +DG+ L       + L+    
Sbjct: 1747 PAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVL-AQRTQALRGGQ- 1804

Query: 777  FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              L +++ Q    G Y   + N  GE     +L +Q
Sbjct: 1805 -RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQ 1839



 Score =  119 bits (297), Expect = 4e-26
 Identities = 99/385 (25%), Positives = 157/385 (40%), Gaps = 45/385 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            C V   P P++ W  +G  +  QE +   + + G  +L L    T DSG YSCTA NA G
Sbjct: 2321 CSVEAEPAPKITWHRDGIVL--QEDAHTQFPERG-RFLQLQALSTADSGDYSCTARNAAG 2377

Query: 495  QLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 554
              S ++ +++  +  +   P   +V  +      Q  +L C   G P P ++W  +  P+
Sbjct: 2378 STSVAFRVEIHTVPTIRSGPPAVNVSVN------QTALLPCQADGVPAPLVSWRKDRVPL 2431

Query: 555  QYARSTCEA-GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
                   E      L IQ  L +D G Y CLA N+ G              S R+   L 
Sbjct: 2432 DPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG--------------SDRQGRDLR 2477

Query: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
             + P     P      S+L +   +   +  + SG+P P V+W  +G ++    DF  +Q
Sbjct: 2478 VLEP-----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL----DFRLQQ 2528

Query: 674  RGTQ----HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
               +    ++L +    P+D+  + C   N  GE      +TV  P     P        
Sbjct: 2529 GAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVP-----PTIADDQTD 2583

Query: 730  VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
             T ++   V+++C   G P PTV W + G  L      + V  +     L + +  P HA
Sbjct: 2584 FTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHA 2640

Query: 790  GQYEILLKNRVGECSCQVSLMLQNS 814
            G+Y    +N  G     V L +Q S
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQAS 2665



 Score =  118 bits (296), Expect = 5e-26
 Identities = 106/388 (27%), Positives = 155/388 (39%), Gaps = 48/388 (12%)

Query: 419  KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
            +P    +     ++  C+  G P+P + W  +G  + R E +                 R
Sbjct: 2219 QPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR----------VLR 2268

Query: 479  TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
             RD+G Y+C A +  G +  S+ ++V+    + V P     +   A   GQ  VL+CSV 
Sbjct: 2269 VRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLA--PGQ-LVLECSVE 2324

Query: 539  GTPVPRITWLLNGQPIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
              P P+ITW  +G  +Q  A +        L +Q     D G Y+C A NA G  S +  
Sbjct: 2325 AEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFR 2384

Query: 598  VTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 657
            V +H                   T P    G   + V       +  Q  G P P V W 
Sbjct: 2385 VEIH-------------------TVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWR 2425

Query: 658  HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
             +   +   S  F     G   SL IQ V  +D G Y C A NSAG  R    L V EP 
Sbjct: 2426 KDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEP- 2481

Query: 717  DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL--CKDTGHFEVLQNE 774
                P     P ++T +     L+ C  +G P P V W +DG+ L      G + +L + 
Sbjct: 2482 ----PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN 2537

Query: 775  DVFTLVLKKVQPWHAGQYEILLKNRVGE 802
                L+L    P  + Q+E ++ N VGE
Sbjct: 2538 ---ALLLTAPGPQDSAQFECVVSNEVGE 2562



 Score =  117 bits (294), Expect = 8e-26
 Identities = 108/407 (26%), Positives = 169/407 (41%), Gaps = 39/407 (9%)

Query: 414  PKFESKPQSQEVK--ENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            P  E++   + +K  + QT    C V+G P+P++ WF +G P+ R +     +       
Sbjct: 1162 PSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAH---HISPDGVL 1218

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L +L+A    +G YSC A+NA G+ +  + L V  LA   +  +  S  ++  V      
Sbjct: 1219 LQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV-LLAPTILGGAEDSADEEVTVTVNNPI 1277

Query: 532  VLQCSVRGTPVPRITWLLNGQPIQYARS-TCEAGVAELHIQDALPEDHGTYTCLAENALG 590
             L C     P P ITW+ +G P + +R+     G   L I +A  ED G YTC+  N LG
Sbjct: 1278 SLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELG 1337

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
                       E   +   E L+P + SK   P+   G+ ++K    S +T+  +    P
Sbjct: 1338 -----------EAVKNYHVEVLIPPSISKDD-PLAEVGVKEVKTKVNSTLTLECESWAVP 1385

Query: 651  PPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE------V 704
            PP + W  +G  +  S     +  G    L IQ     D+G Y C A N AGE      V
Sbjct: 1386 PPTIRWYKDGQPVTPSS--RLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQDFNV 1443

Query: 705  RTQAVLTVQEPHDGTQPW-FISKPRSVTASL--------GQSVLISCAIAGDPFPTVHWL 755
              Q     Q+  D +  +  +S+       +             + C     P P + W 
Sbjct: 1444 LIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWY 1503

Query: 756  RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
            R+ + L        VLQ   V  + L + +  +AG+Y     N VGE
Sbjct: 1504 REDQPLSAG-DEVSVLQGGRVLQIPLVRAE--NAGRYSCKASNEVGE 1547



 Score =  117 bits (292), Expect = 1e-25
 Identities = 105/406 (25%), Positives = 158/406 (38%), Gaps = 50/406 (12%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P   S P +  V  NQT    C+  G+P P V+W  +  P+  +    E+  +     L 
Sbjct: 2391 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGS---LR 2447

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            +     +D+G Y C ASN+ G       L+V  L    +APS S++     +      +L
Sbjct: 2448 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRV--LEPPAIAPSPSNL----TLTAHTPALL 2501

Query: 534  QCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDAL------PEDHGTYTCLAEN 587
             C   G+P P + W  +GQ + +     + G   L   +AL      P+D   + C+  N
Sbjct: 2502 PCEASGSPKPLVVWWKDGQKLDF---RLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSN 2558

Query: 588  ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
             +G+      VTVH                     P      +D  V   + V +T   +
Sbjct: 2559 EVGEAHRLYQVTVH-------------------VPPTIADDQTDFTVTMMAPVVLTCHST 2599

Query: 648  GNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 706
            G P P V W   G ++      +     G   +L I +  P   G YTC A NSAG    
Sbjct: 2600 GIPAPTVSWSKAGAQLGARGSGYRVSPSG---ALEIGQALPIHAGRYTCSARNSAGVAHK 2656

Query: 707  QAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG 766
               LTVQ       P     P  V A   + VL+ C  +G P PT+ W ++G  +     
Sbjct: 2657 HVFLTVQ-----ASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVS 2711

Query: 767  HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
              +VL       L +    P  AG Y  + KN  G    +  L++Q
Sbjct: 2712 -TQVLPGGQ---LRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2753



 Score =  115 bits (289), Expect = 3e-25
 Identities = 92/379 (24%), Positives = 158/379 (41%), Gaps = 42/379 (11%)

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
            +  + V   C V G P   V+W  +G P+   + ++        H L + K +  D+G +
Sbjct: 2044 RPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL---HGSGHTLRISKVQLADAGIF 2100

Query: 486  SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 545
            +C A++  G    ++TLQV+   V+E          D  V+ G    L C  RG P+P +
Sbjct: 2101 TCVAASPAGVADRNFTLQVQVPPVLEPV----EFQNDVVVVRGSLVELPCEARGVPLPLV 2156

Query: 546  TWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 605
            +W+ +G+P+     + E G   L ++     D GTY+C+A +  G+      +TV E   
Sbjct: 2157 SWMKDGEPL--LSQSLEQG-PSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPPH 2213

Query: 606  SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
               S         +PT         +L +  G+ + +     G P P + W  +G  +  
Sbjct: 2214 IEDS--------GQPT---------ELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 2256

Query: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 725
             E+         +S   + +   D G YTC A + AG +     + VQ P +   P    
Sbjct: 2257 LEN---------NSRATRVLRVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGP---R 2304

Query: 726  KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
             PR V       +++ C++  +P P + W RDG  L +D  H +  +      L L+ + 
Sbjct: 2305 GPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED-AHTQFPERGRF--LQLQALS 2361

Query: 786  PWHAGQYEILLKNRVGECS 804
               +G Y    +N  G  S
Sbjct: 2362 TADSGDYSCTARNAAGSTS 2380



 Score =  114 bits (286), Expect = 7e-25
 Identities = 105/389 (26%), Positives = 167/389 (42%), Gaps = 45/389 (11%)

Query: 435  CEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQG 494
            CE  GIP P + WF    PV   E   + Y  AG   L + + + +DSG YSC ASN  G
Sbjct: 1092 CEAMGIPPPAIRWFRGEEPVSPGE---DTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1148

Query: 495  QLSCSWTLQVERLAVMEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 552
            +   +++++V       V PS  +  + +   V++GQ   L C+V G P P++TW  +G+
Sbjct: 1149 EARRNFSVEV------LVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGR 1202

Query: 553  PIQY--ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
            P+    A      GV  L +  A     G Y+C+A NA+G           EK    +  
Sbjct: 1203 PLARGDAHHISPDGVL-LQVLQANLSSAGHYSCIAANAVG-----------EKTKHFQLS 1250

Query: 611  YLLPVAPSKPTAPIFLQGLSD-----LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 665
             LL        AP  L G  D     + V   + +++  +    P P + W+ +G   + 
Sbjct: 1251 VLL--------APTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEA 1302

Query: 666  SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPH-DGTQPWF 723
            S +      GT H L I     ED G YTC   N  GE V+   V  +  P      P  
Sbjct: 1303 SRNIQL-LPGT-HGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLA 1360

Query: 724  ISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 783
                + V   +  ++ + C     P PT+ W +DG+ +   +   +VL    +  L ++ 
Sbjct: 1361 EVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPV-TPSSRLQVLGEGRL--LQIQP 1417

Query: 784  VQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
             Q   +G+Y  +  N  GE     ++++Q
Sbjct: 1418 TQVSDSGRYLCVATNVAGEDDQDFNVLIQ 1446



 Score =  110 bits (274), Expect = 2e-23
 Identities = 78/289 (26%), Positives = 125/289 (43%), Gaps = 26/289 (8%)

Query: 425 VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
           V E+  V+  CE  G+P P + WF +G  +     S +V    G   L L +A++ D+G 
Sbjct: 232 VMEDHLVQLLCEARGVPTPNITWFKDGALLPT---STKVVYTRGGRQLQLGRAQSSDAGV 288

Query: 485 YSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 544
           Y+C ASNA G    +  L V     +E A     V+K    + G+   L+C  RG P P 
Sbjct: 289 YTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVK---AVAGRPVALECVARGHPSPT 345

Query: 545 ITWLLNGQPIQYAR-STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 603
           ++W   G P+  +  S  E   + L ++       G Y+C+A +  G+      V V   
Sbjct: 346 LSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQV- 404

Query: 604 KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI 663
                           P   +  +GL  +  + G  + +  Q SG+P P + WL NG   
Sbjct: 405 ----------------PPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPA 448

Query: 664 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
           +E        +GT  +L I  V  + +G + C+A N AG    +  ++V
Sbjct: 449 EELAGVQVASQGT--TLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV 495



 Score =  106 bits (265), Expect = 2e-22
 Identities = 123/519 (23%), Positives = 195/519 (37%), Gaps = 60/519 (11%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P  E   +  + K N T+   CE   +P P + W+ +G PV      ++V  +     L 
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEG--RLLQ 1414

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCA--------- 524
            +   +  DSG Y C A+N  G+    + + ++   + +    FS+  +  +         
Sbjct: 1415 IQPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV 1474

Query: 525  -----VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAGVAELHIQDALPEDH 578
                 ++E     L C     P P +TW    QP+      +   G   L I     E+ 
Sbjct: 1475 TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENA 1534

Query: 579  GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL----QGLSDLKV 634
            G Y+C A N +G+     W+            Y L V     T P+ L    + + ++ V
Sbjct: 1535 GRYSCKASNEVGE----DWL-----------HYELLVL----TPPVILGDTEELVEEVTV 1575

Query: 635  MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 694
               S V++     GNP P + WL NG     S      + G    +   EV   D  +Y 
Sbjct: 1576 NASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV--ADAASYM 1633

Query: 695  CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVH 753
            C A N AG       L VQ P     P         VTA L  SV + C +   P P V 
Sbjct: 1634 CVAENQAGSAEKLFTLRVQVP-----PRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVT 1688

Query: 754  WLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL-MLQ 812
            W +D +AL       EV       TL L + +   +G Y     N  G     V L +L 
Sbjct: 1689 WYKDSQALSLGE---EVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLV 1745

Query: 813  NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGV 872
              + R  PRG + A    +  G        +D        W   GQ  +  +  + +RG 
Sbjct: 1746 PPAFRQAPRGPQDAVLVRV--GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGG 1803

Query: 873  LKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLS 911
             +  ++  Q +++ +   +V      ++ G+ V T TL+
Sbjct: 1804 QRLEIQEAQVSDKGLYSCKVS-----NVAGEAVRTFTLT 1837



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 100/403 (24%), Positives = 152/403 (37%), Gaps = 52/403 (12%)

Query: 429 QTVKFRCEVSGIPKPEVAWF----LEGTPVR----------RQEGSIEVYEDAGSHYLCL 474
           Q++   C+ +G P PE+ W     L G P+            Q G   + ++  S  L  
Sbjct: 34  QSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS--LHF 91

Query: 475 LKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQ 534
            + +  DSG YSC A N  G     + L V     +  A +   VL     + G D  LQ
Sbjct: 92  PRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLG----LAGADVELQ 147

Query: 535 CSVRGTPVPRITWLLNGQPIQYA--RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQV 592
           C   G P P++ W  + QP+         +     L I  +   D G Y C+A +  GQ 
Sbjct: 148 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHVGDEGRYQCVAFSPAGQQ 207

Query: 593 SCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG---LSDLKVMDGSQVTMTVQVSGN 649
           +    + VH                    AP  + G     ++ VM+   V +  +  G 
Sbjct: 208 ARDFQLRVH--------------------APPTIWGSNETGEVAVMEDHLVQLLCEARGV 247

Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
           P P + W  +G  +  S    + + G Q  L +      D G YTC+A N+ G       
Sbjct: 248 PTPNITWFKDGALLPTSTKVVYTRGGRQ--LQLGRAQSSDAGVYTCKASNAVGAAEKATR 305

Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
           L V  P   T      +P  V A  G+ V + C   G P PT+ W  +G  + +     E
Sbjct: 306 LDVYVP--PTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESN---E 360

Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
                D   L L+      +G Y  +  +  GE   Q S+ +Q
Sbjct: 361 SRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 403



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 107/408 (26%), Positives = 149/408 (36%), Gaps = 33/408 (8%)

Query: 419 KPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKAR 478
           +P   +    + V   C   G P P ++W  EG PV   E +    E  GS  L L    
Sbjct: 320 RPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVA--ESNESRLETDGS-VLRLESPG 376

Query: 479 TRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVR 538
              SG YSC AS+  G+    ++++V+    + VA     V      I GQ   L C   
Sbjct: 377 EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQV----TTIVGQPLELPCQAS 432

Query: 539 GTPVPRITWLLNGQPIQYARSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAW 597
           G+PVP I WL NG+P +       A     LHI     +  G + C A N  G       
Sbjct: 433 GSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVE 492

Query: 598 VTVHEKKSSRKSEYLLPVAPSKPTAPI-----FLQGLSDLKVMDGSQVTMTVQVSGNPPP 652
           V+VH +            AP     PI       +  S         V         PP 
Sbjct: 493 VSVHGE-----------WAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGAHPKPPL 541

Query: 653 EVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
              W   G+   E              L I++V   D G YTC A N AGE + +  L V
Sbjct: 542 VEGWCSPGSLWGEPTGIPVAY-SLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKV 600

Query: 713 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 772
             P    +P  ++K     A    SV + C  +G P P V W +  + +    G   V  
Sbjct: 601 LVP-PNIEPGPVNKAVLENA----SVTLECLASGVPPPDVSWFKGHQPVSSWMG---VTV 652

Query: 773 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 820
           + D   L +++ Q   AG Y  +  N  G    +  L +       LP
Sbjct: 653 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLP 700



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 95/394 (24%), Positives = 136/394 (34%), Gaps = 60/394 (15%)

Query: 429 QTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCT 488
           Q ++  C+ SG P P + W   G P     G     +    H   +       SG ++C 
Sbjct: 423 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLH---IDHVELDHSGLFACQ 479

Query: 489 ASNAQGQLSCSWTLQVERLAVMEVAPSFSSV---LKDCAVIEGQDFVLQCS--------- 536
           A+N  G        +VE     E AP    V              F   C          
Sbjct: 480 ATNEAGTAGA----EVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGWGA 535

Query: 537 ------VRGTPVPRITW-LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
                 V G   P   W    G P+ Y+          L I+     D G YTC A N  
Sbjct: 536 HPKPPLVEGWCSPGSLWGEPTGIPVAYSLPP------PLQIEKVDLRDEGIYTCAATNLA 589

Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
           G+             S R+    + V P+    P+      +  V++ + VT+    SG 
Sbjct: 590 GE-------------SKREVALKVLVPPNIEPGPV------NKAVLENASVTLECLASGV 630

Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
           PPP+V W      +           G    L I++    D G+Y C A N AG    +  
Sbjct: 631 PPPDVSWFKGHQPVSSWMGVTVSVDG--RVLRIEQAQLSDAGSYRCVASNVAGSTELRYG 688

Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALC-KDTGHF 768
           L V  P   T P  +  P  V       V ++C   G P PT+ WL+DG  +    T   
Sbjct: 689 LRVNVPPRITLPPSLPGPVLVNT----PVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGL 744

Query: 769 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 802
           +V     V TL   +     +G+Y  +  + VGE
Sbjct: 745 QVFPGGRVLTLASARAS--DSGRYSCVAVSAVGE 776



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 74/290 (25%), Positives = 105/290 (36%), Gaps = 40/290 (13%)

Query: 528 GQDFVLQCSVRGTPVPRITWL----LNGQPIQYARSTCEAGVAE------------LHIQ 571
           GQ   L+C   G PVP I WL    L G P+ +A    + G  +            LH  
Sbjct: 33  GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92

Query: 572 DALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSD 631
                D G Y+C AEN  G              ++++  +LL + P         Q +  
Sbjct: 93  RIQEGDSGLYSCRAENQAG--------------TAQRDFHLLVLTPPSVLGAGAAQEVLG 138

Query: 632 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 691
           L    G+ V +    SG P P+V W  +   +      H + +     L I      D G
Sbjct: 139 LA---GADVELQCWTSGVPTPQVEWTKDRQPVLPGGP-HLQVQEDGQVLRITGSHVGDEG 194

Query: 692 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPT 751
            Y C A++ AG+      L V  P      W  ++   V       V + C   G P P 
Sbjct: 195 RYQCVAFSPAGQQARDFQLRVHAP---PTIWGSNETGEVAVMEDHLVQLLCEARGVPTPN 251

Query: 752 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
           + W +DG  L   T   +V+       L L + Q   AG Y     N VG
Sbjct: 252 ITWFKDGALLPTST---KVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVG 298



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 59/207 (28%), Positives = 83/207 (40%), Gaps = 42/207 (20%)

Query: 47  GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL---DCGIRGTFSLVIHAVHEEDRGK 103
           GA  + +    G P PQV W ++ QP+  GG  L    D  +     L I   H  D G+
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV-----LRITGSHVGDEGR 195

Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
           Y C A + +G +    +L V                      AP     P+IWG      
Sbjct: 196 YQCVAFSPAGQQARDFQLRVH---------------------AP-----PTIWG------ 223

Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
           + + G V V E  + +  C+  G P P +TW K    L  S +V V  + G Q L++   
Sbjct: 224 SNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKV-VYTRGGRQ-LQLGRA 281

Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSI 250
              D GVYTC   N  G A  +  L +
Sbjct: 282 QSSDAGVYTCKASNAVGAAEKATRLDV 308



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 57/220 (25%), Positives = 85/220 (38%), Gaps = 35/220 (15%)

Query: 32   APAFIL-PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
            AP F L     L ++EG   +     RG P P+++W ++GQP+   G  L      G   
Sbjct: 879  APVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL- 937

Query: 91   LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
            L +        G YTCE +N  G     ++L                           V 
Sbjct: 938  LYLGQAQLAQEGTYTCECSNVVGNSSQDLQL--------------------------EVH 971

Query: 151  TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
              P I G   P         VV++G +    C  TG+P P VTW +   P+   A + + 
Sbjct: 972  VPPQIAGPREPPTQVS----VVQDG-VATLECNATGKPPPTVTWERDGQPV--GAELGLQ 1024

Query: 211  EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
             +N  Q L +        G Y+C+  N +G+A    ELS+
Sbjct: 1025 LQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSV 1064



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 57/238 (23%), Positives = 91/238 (38%), Gaps = 52/238 (21%)

Query: 16   SLSVDPSRVDSM-PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
            S+ V P  +  + PLT   A +  P  L  +            G P P + W R  +P++
Sbjct: 1063 SVLVPPELIGDLDPLTNITAALHSPLTLLCE----------AMGIPPPAIRWFRGEEPVS 1112

Query: 75   SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTVELTVEGSFAKQLG 132
             G    L   + G + L +    E+D G Y+C A+N  G   R  +VE+ V  S   +  
Sbjct: 1113 PGEDTYL---LAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDL 1169

Query: 133  QPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQV 192
            + V+                                   V +GQ     C +TG PQP++
Sbjct: 1170 EEVIK----------------------------------VLDGQTAHLMCNVTGHPQPKL 1195

Query: 193  TWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            TW K   PL       +S      +L++   N    G Y+C+  N  G+ +   +LS+
Sbjct: 1196 TWFKDGRPLARGDAHHISPDG--VLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSV 1251



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 58/214 (27%), Positives = 85/214 (39%), Gaps = 46/214 (21%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG----RFLLDCGIRGTFSLVIHAVHEE 99
            + EG   + +    G P P V W ++G P+        RF LD G     SLV+  +   
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-----SLVLKGLRAS 2001

Query: 100  DRGKYTCEATNGSG--ARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
            D G YTC A N +G  AR  TV + V                             P+I  
Sbjct: 2002 DAGAYTCVAHNPAGEDARLHTVNVLVP----------------------------PTI-- 2031

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
                + A   G +V + G++    C + G P   V+WLK  +PL  S R  +        
Sbjct: 2032 ---KQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG--HT 2086

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
            L I  V   D G++TC+  + +G A  +  L +Q
Sbjct: 2087 LRISKVQLADAGIFTCVAASPAGVADRNFTLQVQ 2120



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 56/236 (23%), Positives = 89/236 (37%), Gaps = 36/236 (15%)

Query: 15  TSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT 74
           T+L+ +  R  ++ +   P     P N  + E A+   E    G P P V+W +  QP++
Sbjct: 586 TNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPVS 645

Query: 75  SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQP 134
           S     +    R    L I      D G Y C A+N +G+ ++   L V           
Sbjct: 646 SWMGVTVSVDGR---VLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVN---------- 692

Query: 135 VVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
                       P +   PS+ G  P    T +           R +C  TG P P + W
Sbjct: 693 ----------VPPRITLPPSLPG--PVLVNTPV-----------RLTCNATGAPSPTLMW 729

Query: 195 LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
           LK   P+ P+    +    G +VL +      D G Y+C+ V+  G+      L +
Sbjct: 730 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 785



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 61/246 (24%), Positives = 92/246 (37%), Gaps = 48/246 (19%)

Query: 8    ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
            A + + +T  +V    V   P+ +  AF      L    G + + +  VRG P P + W 
Sbjct: 2917 AENRVGRTQ-AVSFVHVKEAPVLQGEAFSY----LVEPVGGSIQLDCVVRGDPVPDIHWI 2971

Query: 68   RNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
            ++G P+     R  L  G     SL I     +D G+Y C A N  G  +  V L ++  
Sbjct: 2972 KDGLPLRGSHLRHQLQNG-----SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQ-- 3024

Query: 127  FAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
                              SAP  +  P                + V+ G      C+ TG
Sbjct: 3025 ------------------SAPVFQVEPQ--------------DMTVRSGDDVALRCQATG 3052

Query: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
             P P + WL+   PL+ S R+          L +  V   D G Y C+  N  G A+  A
Sbjct: 3053 EPTPTIEWLQAGQPLRASRRLRTLPDGS---LWLENVETGDAGTYDCVAHNLLGSATARA 3109

Query: 247  ELSIQG 252
             L ++G
Sbjct: 3110 FLVVRG 3115



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 50/213 (23%), Positives = 81/213 (38%), Gaps = 36/213 (16%)

Query: 38   PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
            PP  + + +   A  E    G P P VTW R+GQP+  G    L    +G  SL +    
Sbjct: 982  PPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPV--GAELGLQLQNQGQ-SLHVERAQ 1038

Query: 98   EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
                G+Y+C A N +G  +   EL                          +V   P + G
Sbjct: 1039 AAHTGRYSCVAENLAGRAERKFEL--------------------------SVLVPPELIG 1072

Query: 158  ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
            +  P     L  +           C+  G P P + W +G  P+ P     +    G  +
Sbjct: 1073 DLDP-----LTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLA--GGWM 1125

Query: 218  LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
            L++    + D G+Y+CL  N +G+A  +  + +
Sbjct: 1126 LKMTQTQEQDSGLYSCLASNEAGEARRNFSVEV 1158



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 49/195 (25%), Positives = 79/195 (40%), Gaps = 36/195 (18%)

Query: 59   YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQ 116
            +P P +TW ++G P  +     L   + GT  L I    +ED G+YTC  TN  G   + 
Sbjct: 1286 FPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKN 1342

Query: 117  VTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ 176
              VE+ +  S +K            D  +   V+           +  TK+   +  E  
Sbjct: 1343 YHVEVLIPPSISKD-----------DPLAEVGVK-----------EVKTKVNSTLTLE-- 1378

Query: 177  MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
                 C+    P P + W K   P+ PS+R+ V  +   ++L+I      D G Y C+  
Sbjct: 1379 -----CESWAVPPPTIRWYKDGQPVTPSSRLQVLGEG--RLLQIQPTQVSDSGRYLCVAT 1431

Query: 237  NGSGKASMSAELSIQ 251
            N +G+      + IQ
Sbjct: 1432 NVAGEDDQDFNVLIQ 1446



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 50/199 (25%), Positives = 80/199 (40%), Gaps = 34/199 (17%)

Query: 44   IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
            + +G TA     V G+P+P++TW ++G+P+  G    +     G    V+ A +    G 
Sbjct: 1175 VLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD--GVLLQVLQA-NLSSAGH 1231

Query: 104  YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
            Y+C A N  G +    +L+V       L  P +   LG    +   E             
Sbjct: 1232 YSCIAANAVGEKTKHFQLSV-------LLAPTI---LGGAEDSADEE------------- 1268

Query: 164  ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGV 223
                  V V         C+    P P +TW+K   P + S  + +    G   L+I   
Sbjct: 1269 ------VTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNA 1320

Query: 224  NQDDVGVYTCLVVNGSGKA 242
             ++D G YTC+V N  G+A
Sbjct: 1321 QKEDAGQYTCVVTNELGEA 1339



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 57/224 (25%), Positives = 80/224 (35%), Gaps = 44/224 (19%)

Query: 31   EAPAFILPPRNLCIKEGATAK---FEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
            +AP  I+ PR      G        E  V   P P++TWHR+G  +            RG
Sbjct: 2295 QAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFP--ERG 2352

Query: 88   TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
             F L + A+   D G Y+C A N +G+  V   + +                     + P
Sbjct: 2353 RF-LQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH--------------------TVP 2391

Query: 148  AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SAR 206
             + + P                V V   Q     C+  G P P V+W K  VPL P S R
Sbjct: 2392 TIRSGPP--------------AVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPR 2437

Query: 207  VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
              +  +     L I  V   D G Y CL  N +G      +L +
Sbjct: 2438 FEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV 2478



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 64/279 (22%), Positives = 94/279 (33%), Gaps = 51/279 (18%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            +P  K     V     +++LL C+ S  P  TI W   G  + T     +   G L    
Sbjct: 2665 SPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQL---R 2721

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP----- 1211
            I  A PED G Y C+AKN AG A    ++ V   P  EN       +    + LP     
Sbjct: 2722 IAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARG 2781

Query: 1212 -------------PVLGTESDATVKK--------------------------KPAPKTPP 1232
                         PV G E   T++                           +   +   
Sbjct: 2782 SPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHL 2841

Query: 1233 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
               + P     P D+ +R G+ + L     G+      W    + + E     V   + G
Sbjct: 2842 TILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGG 2897

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            S L   A  +E  G Y    EN++G  QA   + V + P
Sbjct: 2898 STLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAP 2936



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 41/195 (21%)

Query: 56   VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
            VRG P   V+W ++G P+    R LL        +L I  V   D G +TC A + +G  
Sbjct: 2055 VRGSPPIHVSWLKDGLPLPLSQRTLLH---GSGHTLRISKVQLADAGIFTCVAASPAGV- 2110

Query: 116  QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
                    + +F  Q+  P            P +E         P +F      VVV  G
Sbjct: 2111 -------ADRNFTLQVQVP------------PVLE---------PVEFQND---VVVVRG 2139

Query: 176  QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
             +    C+  G P P V+W+K   PL     +S S + G   L++  V   D G Y+C+ 
Sbjct: 2140 SLVELPCEARGVPLPLVSWMKDGEPL-----LSQSLEQGPS-LQLEAVGAGDSGTYSCVA 2193

Query: 236  VNGSGKASMSAELSI 250
            V+ +G+A    +L++
Sbjct: 2194 VSEAGEARRHFQLTV 2208



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 49/201 (24%), Positives = 80/201 (39%), Gaps = 48/201 (23%)

Query: 57  RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
           RG P P +TW ++G  + +  + +     RG   L +      D G YTC+A+N  GA +
Sbjct: 245 RGVPTPNITWFKDGALLPTSTKVVYT---RGGRQLQLGRAQSSDAGVYTCKASNAVGAAE 301

Query: 117 VTVEL------TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
               L      T+EG+     G+P V K +                           GR 
Sbjct: 302 KATRLDVYVPPTIEGAG----GRPYVVKAVA--------------------------GRP 331

Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
           V  E       C   G P P ++W    +P+  S   S  E +G  VL +    +   G+
Sbjct: 332 VALE-------CVARGHPSPTLSWHHEGLPVAESNE-SRLETDG-SVLRLESPGEASSGL 382

Query: 231 YTCLVVNGSGKASMSAELSIQ 251
           Y+C+  + +G+A +   + +Q
Sbjct: 383 YSCVASSPAGEAVLQYSVEVQ 403



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 55/220 (25%), Positives = 80/220 (36%), Gaps = 53/220 (24%)

Query: 47  GATAKFEGRVRGYPEPQVTWHRNGQPI----------------TSGGRFLLDCGIRGTFS 90
           G +   E    G+P P++ W ++ Q +                  GG  LLD G     S
Sbjct: 33  GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQ----S 88

Query: 91  LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
           L    + E D G Y+C A N +G  Q    L                           V 
Sbjct: 89  LHFPRIQEGDSGLYSCRAENQAGTAQRDFHL--------------------------LVL 122

Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
           T PS+ G      A     V+   G      C  +G P PQV W K   P+ P       
Sbjct: 123 TPPSVLG------AGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV 176

Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
           +++G QVL I G +  D G Y C+  + +G+ +   +L +
Sbjct: 177 QEDG-QVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV 215



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 61/259 (23%), Positives = 96/259 (37%), Gaps = 54/259 (20%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQD----VHVAEGKKLLLQCQVSSDPPATIIWT 1132
            C+  +A   D +    S    PAF+Q  +     V V  G K +L C+  + P  T+ W 
Sbjct: 1726 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1785

Query: 1133 LNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
             +G+ L   +     + G    + I++A   D+GLY C   N AG+A  +  +TV   P 
Sbjct: 1786 KDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPT 1843

Query: 1193 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1252
             EN K                  TE+ + V                            AG
Sbjct: 1844 FENPK------------------TETVSQV----------------------------AG 1857

Query: 1253 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1312
              + L   V+G    T TW+K R  ++ S    V +   G +L +   +    G YT + 
Sbjct: 1858 SPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVS--RGGRLQLSRLQPAQAGTYTCVA 1915

Query: 1313 ENKLGSRQAQVNLTVVDKP 1331
            EN     +    + V+  P
Sbjct: 1916 ENTQAEARKDFVVAVLVAP 1934



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 8/119 (6%)

Query: 1721 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1780
            +  G+ T      + E+ +D   A L A     P ++   S   R+  V+EG   R DC+
Sbjct: 1906 AQAGTYTCVAENTQAEARKDFVVAVLVA-----PRIRS--SGVAREHHVLEGQEVRLDCE 1958

Query: 1781 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
             +G P P+V W KD   + +     + +  DG  SL++  +   D   YTC A N  GE
Sbjct: 1959 ADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGG-SLVLKGLRASDAGAYTCVAHNPAGE 2016



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 3/96 (3%)

Query: 1096 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1155
            +AP F+ + QD+ V  G  + L+CQ + +P  TI W   G+ L+ ++ +    +GSL   
Sbjct: 3025 SAPVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLE 3084

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
            ++E     D G Y CVA N  G A     + V   P
Sbjct: 3085 NVETG---DAGTYDCVAHNLLGSATARAFLVVRGEP 3117



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 67/282 (23%), Positives = 101/282 (35%), Gaps = 62/282 (21%)

Query: 1104 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1163
            L  V    G+ L L CQ S  P  TI W  NG+  +    + ++ +G+  ++ I+    +
Sbjct: 414  LGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGT--TLHIDHVELD 471

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVD--------DAPASENTKAPEMKSRRPKSSLPP--- 1212
              GL+ C A N+AG A    +V+V         + P  +     E  S  P +  PP   
Sbjct: 472  HSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHR 531

Query: 1213 ----------VLGTESDATVKKKP-----APKTPP------------------------- 1232
                      V G  S  ++  +P     A   PP                         
Sbjct: 532  GWGAHPKPPLVEGWCSPGSLWGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGE 591

Query: 1233 -------KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1285
                   K  +PP I   P ++ V    SV L    +G  P   +W K  + +  S  M 
Sbjct: 592  SKREVALKVLVPPNIEPGPVNKAVLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMG 649

Query: 1286 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            V  S +G  L I  A+    G Y  +  N  GS + +  L V
Sbjct: 650  VTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRV 691



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 65/285 (22%), Positives = 107/285 (37%), Gaps = 53/285 (18%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            V V +     L+C  +  PP T+ W  +G+ +     + L  +G   S+ +E+A     G
Sbjct: 986  VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTG 1043

Query: 1167 LYKCVAKNDAGQAECSCQVTV--------DDAPASENTKA----------------PEMK 1202
             Y CVA+N AG+AE   +++V        D  P +  T A                P ++
Sbjct: 1044 RYSCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIR 1103

Query: 1203 SRRPKSSLPPVLGT---------------ESDATVKKKPAPKTPPKA--------AMPPQ 1239
              R +  + P   T               E D+ +    A     +A         +PP 
Sbjct: 1104 WFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPS 1163

Query: 1240 I--IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1297
            I      E  KV  G++  L   VTG      TW K  + +   +   +  S +G  L +
Sbjct: 1164 IENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHI--SPDGVLLQV 1221

Query: 1298 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1342
            L A     G Y+ +  N +G +     L+V+  P    G   ++D
Sbjct: 1222 LQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSAD 1266



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 54/255 (21%)

Query: 2   GDVKLVASSHISKTSLSVD-----PSRVDSMPLTEAPAFI-LPPRNLCIKEGATAKFEGR 55
           G  + VAS+    T L        P R+   P    P  +  P R  C   GA       
Sbjct: 670 GSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNATGA------- 722

Query: 56  VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
               P P + W ++G P++  G   L     G   L + +    D G+Y+C A +  G  
Sbjct: 723 ----PSPTLMWLKDGNPVSPAGTPGLQV-FPGGRVLTLASARASDSGRYSCVAVSAVGED 777

Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
           +  V L V                             PSI GE       +L   VV   
Sbjct: 778 RQDVVLQVH--------------------------MPPSILGE-------ELNVSVVANE 804

Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
            +    C+    P P ++W K   PL+P   V +S    +  L++   +  D G YTC  
Sbjct: 805 SVA-LECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDAGHYTCEA 861

Query: 236 VNGSGKASMSAELSI 250
           +N +G +     L++
Sbjct: 862 LNQAGHSEKHYNLNV 876



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 3/93 (3%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P     + DL   EGS A   CK  G P+P + W KD Q +  +   +  +    +  
Sbjct: 2754 VPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGA---EGKFTIQPSGE 2810

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
            L++ ++ G D   YTC A N++G A     L +
Sbjct: 2811 LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2843



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 56/239 (23%), Positives = 91/239 (38%), Gaps = 41/239 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P  +  +++V       L L+C+  + PP TI W  +G+ +  +  + +  EG L  + I
Sbjct: 1358 PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRL--LQI 1415

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP----ASENTKAPEMKSRRPKSSLPPV 1213
            +     D G Y CVA N AG+ +    V +   P      + + A E+ SR  ++     
Sbjct: 1416 QPTQVSDSGRYLCVATNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGV- 1474

Query: 1214 LGTESDATVKKKPA-PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
              TE    V+  PA       A  PP +  + EDQ + AG+ V +               
Sbjct: 1475 --TEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVL-------------- 1518

Query: 1273 KFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
                             + G  L I   R E+ G Y+    N++G       L V+  P
Sbjct: 1519 -----------------QGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP 1560



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 52/234 (22%), Positives = 83/234 (35%), Gaps = 69/234 (29%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G  + L C V  DP   I W  +G  L+ +      Q GSL   +I +   +D G Y+C+
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSL---TIRRTERDDAGRYQCL 3007

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A+N+ G A+    + +  AP  +                                     
Sbjct: 3008 AENEMGVAKKVVILVLQSAPVFQVE----------------------------------- 3032

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK------ 1285
                        P+D  VR+G+ V L  + TG    T  W++  + ++ S  ++      
Sbjct: 3033 ------------PQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGS 3080

Query: 1286 --VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1337
              +EN E G             G Y  +  N LGS  A+  L V  +P    G+
Sbjct: 3081 LWLENVETGD-----------AGTYDCVAHNLLGSATARAFLVVRGEPQGSWGS 3123



 Score = 48.9 bits (115), Expect = 5e-05
 Identities = 47/219 (21%), Positives = 77/219 (35%), Gaps = 48/219 (21%)

Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1168
            V E   + L+C  S  PP  + W    + + +   + +S +G +  + IE+A   D G Y
Sbjct: 615  VLENASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRV--LRIEQAQLSDAGSY 672

Query: 1169 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1228
            +CVA N AG  E    + V+                                        
Sbjct: 673  RCVASNVAGSTELRYGLRVN---------------------------------------- 692

Query: 1229 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1288
              PP+  +PP +        V     V L    TG    T  W+K    +  +    ++ 
Sbjct: 693  -VPPRITLPPSL-----PGPVLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQV 746

Query: 1289 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
               G  LT+ +AR    G Y+ +  + +G  +  V L V
Sbjct: 747  FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 785



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 49/220 (22%), Positives = 83/220 (37%), Gaps = 53/220 (24%)

Query: 1112 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1171
            G+ + + C V   PP  + W  +G  L  ++  +L   GS  ++ I K    D G++ CV
Sbjct: 2046 GELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLL--HGSGHTLRISKVQLADAGIFTCV 2103

Query: 1172 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1231
            A + AG A+ +  + V                      +PPVL                 
Sbjct: 2104 AASPAGVADRNFTLQV---------------------QVPPVL----------------- 2125

Query: 1232 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1291
                   + ++F  D  V  G  VEL  +  G      +WMK      + E +  ++ E 
Sbjct: 2126 -------EPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMK------DGEPLLSQSLEQ 2172

Query: 1292 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            G  L + A      G Y+ +  ++ G  +    LTV++ P
Sbjct: 2173 GPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEPP 2212



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 18/181 (9%)

Query: 635 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI-------QESEDFHFEQRGTQ------HSLC 681
           M G  +T+    +G P PE++WL +   +           D  + Q G         SL 
Sbjct: 31  MAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLH 90

Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
              +   D+G Y+C A N AG  +    L V  P            + V    G  V + 
Sbjct: 91  FPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTP---PSVLGAGAAQEVLGLAGADVELQ 147

Query: 742 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 801
           C  +G P P V W +D + +     H +V ++  V  +    V     G+Y+ +  +  G
Sbjct: 148 CWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--GDEGRYQCVAFSPAG 205

Query: 802 E 802
           +
Sbjct: 206 Q 206



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 52/234 (22%), Positives = 84/234 (35%), Gaps = 46/234 (19%)

Query: 1107 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1166
            + V +G+   L C V+  P   + W  +G+ L       +S +G L  V   +A     G
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVL--QANLSSAG 1230

Query: 1167 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1226
             Y C+A N  G+     Q++V  AP                     +LG   D+      
Sbjct: 1231 HYSCIAANAVGEKTKHFQLSVLLAPT--------------------ILGGAEDSA----- 1265

Query: 1227 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1286
                              E+  V     + L  +         TWMK     + S ++++
Sbjct: 1266 -----------------DEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQL 1308

Query: 1287 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCA 1340
                +G  L IL A++E  G YT +V N+LG      ++ V+  P      P A
Sbjct: 1309 LPGTHG--LQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLA 1360



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 60/228 (26%), Positives = 89/228 (39%), Gaps = 21/228 (9%)

Query: 1008 VESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAE---------TLKPMGNAKPDEN 1058
            V    P +   P GP   VG A     L+    A+PA           L+   + +  E 
Sbjct: 2292 VRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER 2351

Query: 1059 LKSASKEELKKDVKNDVNCK-RGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLL 1117
             +    + L      D +C  R  AG+T    R E   T P  +     V+V+  +  LL
Sbjct: 2352 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIH-TVPTIRSGPPAVNVSVNQTALL 2410

Query: 1118 QCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1175
             CQ    P   + W  +   L  ++ +F IL  EGSL    I+  L +D G Y C+A N 
Sbjct: 2411 PCQADGVPAPLVSWRKDRVPLDPRSPRFEILP-EGSL---RIQPVLAQDAGHYLCLASNS 2466

Query: 1176 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            AG       + V + PA     AP   +    +  P +L  E+  + K
Sbjct: 2467 AGSDRQGRDLRVLEPPAI----APSPSNLTLTAHTPALLPCEASGSPK 2510



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F    +D+ V  G      C+  G P P + W +  Q +R SR  +   D     SL 
Sbjct: 3027 PVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG----SLW 3082

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 1854
            + +V   D   Y C A N LG AT  A L+V    +G
Sbjct: 3083 LENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQG 3119



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 3/93 (3%)

Query: 1768 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1827
            E+VE + A   C     P P++ W+++DQ +       +     G   L I  V  ++  
Sbjct: 1479 EIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSV---LQGGRVLQIPLVRAENAG 1535

Query: 1828 KYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
            +Y+CKA N +GE     EL+V T     G+ EE
Sbjct: 1536 RYSCKASNEVGEDWLHYELLVLTPPVILGDTEE 1568



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 60/271 (22%), Positives = 108/271 (39%), Gaps = 53/271 (19%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V E   + L C+    P   I W  +G  L T+  ++ ++ G    + + +A   D 
Sbjct: 229  EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGR--QLQLGRAQSSDA 286

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENT--------------KAPEMKSR-RPKSSL 1210
            G+Y C A N  G AE + ++ V   P  E                 A E  +R  P  +L
Sbjct: 287  GVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTL 346

Query: 1211 P------PVLGT-----ESDATVKKKPAP------------KTPPKAA---------MPP 1238
                   PV  +     E+D +V +  +P             +P   A         +PP
Sbjct: 347  SWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQVPP 406

Query: 1239 QIIQFPEDQKVR--AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
            Q++      +V    G+ +EL  + +G+   T  W++  +  +E   ++V  +  G+ L 
Sbjct: 407  QLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQWLQNGRPAEELAGVQV--ASQGTTLH 464

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
            I     +H G +     N+ G+  A+V ++V
Sbjct: 465  IDHVELDHSGLFACQATNEAGTAGAEVEVSV 495



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 6/101 (5%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            DV V  G  + L C+    P   + W  +G+ L +       ++G   S+ +E     D 
Sbjct: 2133 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL----EQGP--SLQLEAVGAGDS 2186

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
            G Y CVA ++AG+A    Q+TV + P  E++  P   S  P
Sbjct: 2187 GTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTP 2227



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 28/93 (30%), Positives = 40/93 (43%), Gaps = 3/93 (3%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            ++ V+E    +  C+  G P P + WFKD   +  S   ++ Y   G   L +      D
Sbjct: 229  EVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTST--KVVYTRGGR-QLQLGRAQSSD 285

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1858
               YTCKA N++G A     L V      EG G
Sbjct: 286  AGVYTCKASNAVGAAEKATRLDVYVPPTIEGAG 318



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 6/99 (6%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            ++V++G  A   C + G+P P++ WFKD + +       I  D      L +        
Sbjct: 1173 IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPD---GVLLQVLQANLSSA 1229

Query: 1827 AKYTCKAVNSLGEAT---CTAELIVETMEEGEGEGEEEE 1862
              Y+C A N++GE T     + L+  T+  G  +  +EE
Sbjct: 1230 GHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEE 1268



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            +V V   + + L+CQ  + PP  + W  +G+ L+    + LS + +L  + +++A   D 
Sbjct: 797  NVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKAL--LQVDRADVWDA 854

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAP 1191
            G Y C A N AG +E    + V  AP
Sbjct: 855  GHYTCEALNQAGHSEKHYNLNVWVAP 880



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 24/80 (30%), Positives = 39/80 (48%), Gaps = 2/80 (2%)

Query: 1101 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKA 1160
            ++ +++V V     + LQC    +P  TI W  NG     +  + + ++G +  VS  + 
Sbjct: 1567 EELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEV 1626

Query: 1161 LPEDRGLYKCVAKNDAGQAE 1180
               D   Y CVA+N AG AE
Sbjct: 1627 --ADAASYMCVAENQAGSAE 1644



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 7/97 (7%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1825
            D+ VV GS     C+  G P P V W KD + +       +    +   SL +  V   D
Sbjct: 2133 DVVVVRGSLVELPCEARGVPLPLVSWMKDGEPL-------LSQSLEQGPSLQLEAVGAGD 2185

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
               Y+C AV+  GEA    +L V      E  G+  E
Sbjct: 2186 SGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTE 2222



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 77/363 (21%), Positives = 129/363 (35%), Gaps = 71/363 (19%)

Query: 987  GKKKLPAENGSSSAETLNA-----KAVESS---KPLSNAQPSGPLKPV-GNAKPAETLKP 1037
            G+ +L +++G  + E LNA     K V+ S    P     P GP   V         L  
Sbjct: 1714 GRARL-SDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSC 1772

Query: 1038 MGNAKPAETL------KPMGNAKPDENLKSASKEELKKDVKND---VNCKRGHAGTTDNE 1088
              +A P  T+      +P+  A+  + L+   + E+++   +D    +CK  +       
Sbjct: 1773 ETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVR 1832

Query: 1089 KRSESQGTAPAFKQ-KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI-IL 1146
              + +    P F+  K + V    G  L+L C VS  P  T+ W  +   ++++    ++
Sbjct: 1833 TFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVV 1892

Query: 1147 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1206
            S+ G L    + +  P   G Y CVA+N   +A     V V  AP             R 
Sbjct: 1893 SRGGRL---QLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP-------------RI 1936

Query: 1207 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1266
            +SS                                    +  V  G+ V L  +  G  P
Sbjct: 1937 RSS--------------------------------GVAREHHVLEGQEVRLDCEADGQPP 1964

Query: 1267 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVN 1324
                W+K    + +     +    +G  L +   R    G YT +  N  G  +R   VN
Sbjct: 1965 PDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVN 2024

Query: 1325 LTV 1327
            + V
Sbjct: 2025 VLV 2027



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRES--RHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            G + + DC + G P P++ W KD   +R S  RH      +  N SL I     DD  +Y
Sbjct: 2951 GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH------QLQNGSLTIRRTERDDAGRY 3004

Query: 1830 TCKAVNSLGEATCTAELIVET 1850
             C A N +G A     L++++
Sbjct: 3005 QCLAENEMGVAKKVVILVLQS 3025



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+   +P P + W KD      SR+ Q+     G   L I +   +D  +YTC   N LG
Sbjct: 1281 CEALAFPSPNITWMKDGAPFEASRNIQL---LPGTHGLQILNAQKEDAGQYTCVVTNELG 1337

Query: 1839 EA 1840
            EA
Sbjct: 1338 EA 1339



 Score = 41.6 bits (96), Expect = 0.007
 Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1831
            G  A   C+ +  P+P V W+KD Q +  ++  Q      G   L I +    D   Y+C
Sbjct: 1765 GDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQA---LRGGQRLEIQEAQVSDKGLYSC 1821

Query: 1832 KAVNSLGEATCTAELIVE 1849
            K  N  GEA  T  L V+
Sbjct: 1822 KVSNVAGEAVRTFTLTVQ 1839



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 6/86 (6%)

Query: 1766 DLEVVEG---SAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1822
            DLE V     S+    C +  +P+PEV W+KD Q++         +   G  +L +    
Sbjct: 1661 DLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEV---FLLPGTHTLQLGRAR 1717

Query: 1823 GDDDAKYTCKAVNSLGEATCTAELIV 1848
              D   YTC+A+N+ G      +L V
Sbjct: 1718 LSDSGMYTCEALNAAGRDQKLVQLSV 1743



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 46/243 (18%), Positives = 84/243 (34%), Gaps = 53/243 (21%)

Query: 1089 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1148
            +  E++G    +++      + E     L C  ++ PP  + W    + L     + + Q
Sbjct: 1466 REEEARGGVTEYRE------IVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQ 1519

Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKS 1208
             G +  + + +A  E+ G Y C A N+ G+     ++ V                     
Sbjct: 1520 GGRVLQIPLVRA--ENAGRYSCKASNEVGEDWLHYELLV--------------------- 1556

Query: 1209 SLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPIT 1268
              PPV+  +++  V                      E+  V A  +V L     G    T
Sbjct: 1557 LTPPVILGDTEELV----------------------EEVTVNASSTVSLQCPALGNPVPT 1594

Query: 1269 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1328
             +W++       S  ++V   E+G  L +  A       Y  + EN+ GS +    L V 
Sbjct: 1595 ISWLQNGLPFSPSPRLQV--LEDGQVLQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQ 1652

Query: 1329 DKP 1331
              P
Sbjct: 1653 VPP 1655



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)

Query: 1077 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1136
            C   ++  +D + R       PA      ++ +      LL C+ S  P   ++W  +G+
Sbjct: 2461 CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQ 2520

Query: 1137 TLKTTKFIILSQEGSLCSVSIEKAL-----PEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
             L         Q+G+   +     L     P+D   ++CV  N+ G+A    QVTV   P
Sbjct: 2521 KLD-----FRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPP 2575



 Score = 39.3 bits (90), Expect = 0.036
 Identities = 65/278 (23%), Positives = 93/278 (33%), Gaps = 49/278 (17%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSVS 1156
            P       D  V     ++L C  +  P  T+ W+  G  L        +S  G+L    
Sbjct: 2575 PTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL---E 2631

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP------------ASENTKAPEMKSR 1204
            I +ALP   G Y C A+N AG A     +TV  +P            A E    P   S 
Sbjct: 2632 IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASG 2691

Query: 1205 RP-------KSSLPPVLGTESDA--------------------TVKKKPA----PKTPPK 1233
             P       K  L    G  +                       + K  A     KT   
Sbjct: 2692 IPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLV 2751

Query: 1234 AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1293
              +PP I     D     G    L  K  G+     TW K  + +  +E  K     +G 
Sbjct: 2752 VQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEG-KFTIQPSG- 2809

Query: 1294 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            +L +     +  G YT   EN +G  + +V+LT++  P
Sbjct: 2810 ELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLP 2847



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 36/157 (22%), Positives = 64/157 (40%), Gaps = 15/157 (9%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1164
            ++V V     + L C+  + P   I W  +G   + ++ I L        + I  A  ED
Sbjct: 1267 EEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLP--GTHGLQILNAQKED 1324

Query: 1165 RGLYKCVAKNDAGQAECSCQVTVDDAPA-SENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
             G Y CV  N+ G+A  +  V V   P+ S++    E+  +  K+ +   L  E ++   
Sbjct: 1325 AGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESW-- 1382

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
                      A  PP I  + + Q V     +++ G+
Sbjct: 1383 ----------AVPPPTIRWYKDGQPVTPSSRLQVLGE 1409



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 27/103 (26%), Positives = 41/103 (39%), Gaps = 12/103 (11%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIR-----ESRHFQIDYDE-------DGNCSLIIS 1819
            G +   +C   G+P PE+VW KD Q +          + + + +       D   SL   
Sbjct: 33   GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFP 92

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
             +   D   Y+C+A N  G A     L+V T     G G  +E
Sbjct: 93   RIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQE 135



 Score = 38.1 bits (87), Expect = 0.081
 Identities = 51/235 (21%), Positives = 84/235 (35%), Gaps = 55/235 (23%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F     D  +  G +L L+C     P   I WT+N + +       +S++    ++  
Sbjct: 2847 PVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQR 2902

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT- 1216
                 ED G Y C A+N  G+ +    V V +AP  +      +        + PV G+ 
Sbjct: 2903 AAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSYL--------VEPVGGSI 2954

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
            + D  V+  P P                                          W+K   
Sbjct: 2955 QLDCVVRGDPVP---------------------------------------DIHWIKDGL 2975

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
             ++ S H++    +NGS LTI    ++  G Y  L EN++G  +  V L +   P
Sbjct: 2976 PLRGS-HLR-HQLQNGS-LTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQSAP 3027



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 52/250 (20%), Positives = 85/250 (34%), Gaps = 45/250 (18%)

Query: 2    GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
            GD    A +    TS++    RV+   +   P     P  + +    TA    +  G P 
Sbjct: 2366 GDYSCTARNAAGSTSVAF---RVE---IHTVPTIRSGPPAVNVSVNQTALLPCQADGVPA 2419

Query: 62   PQVTWHRNGQPITSGG-RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            P V+W ++  P+     RF     I    SL I  V  +D G Y C A+N +G+ +   +
Sbjct: 2420 PLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRD 2475

Query: 121  LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
            L V                       PA+   PS               + +        
Sbjct: 2476 LRV--------------------LEPPAIAPSPS--------------NLTLTAHTPALL 2501

Query: 181  SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
             C+ +G P+P V W K    L    +           L +      D   + C+V N  G
Sbjct: 2502 PCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVG 2561

Query: 241  KASMSAELSI 250
            +A    ++++
Sbjct: 2562 EAHRLYQVTV 2571



 Score = 37.7 bits (86), Expect = 0.11
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 1/83 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P  + +  +L +   + A   C+  G P P VVW+KD Q + + R  Q  Y    + +L+
Sbjct: 2482 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKL-DFRLQQGAYRLLPSNALL 2540

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEA 1840
            ++     D A++ C   N +GEA
Sbjct: 2541 LTAPGPQDSAQFECVVSNEVGEA 2563



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 35/149 (23%), Positives = 56/149 (37%), Gaps = 8/149 (5%)

Query: 1694 WQKTG---NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1750
            W K G    A R I  L     +  L+ +K   G  T  +  E  E+ ++     L   +
Sbjct: 1293 WMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPS 1352

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
              K    P     +++++    S    +C+    P P + W+KD Q +  S   Q+  + 
Sbjct: 1353 ISKDD--PLAEVGVKEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGE- 1409

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
                 L I      D  +Y C A N  GE
Sbjct: 1410 --GRLLQIQPTQVSDSGRYLCVATNVAGE 1436



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 8/105 (7%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K G        L S ++  G S +  + G+  S   +    SE   ++   +    E 
Sbjct: 2158 WMKDGEP------LLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVMEP 2211

Query: 1754 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI 1798
            PH++     T  +L +  G+     C  +G P P + W KD Q++
Sbjct: 2212 PHIEDSGQPT--ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL 2254



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 4/92 (4%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1830
            G+     C   G P P+V W KD Q +     H Q+   EDG    I     G D+ +Y 
Sbjct: 141  GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV--QEDGQVLRITGSHVG-DEGRYQ 197

Query: 1831 CKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1862
            C A +  G+     +L V       G  E  E
Sbjct: 198  CVAFSPAGQQARDFQLRVHAPPTIWGSNETGE 229



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 3/82 (3%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            + VV+   A  +C   G P P V W +D Q +      Q+   ++   SL +        
Sbjct: 986  VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQL---QNQGQSLHVERAQAAHT 1042

Query: 1827 AKYTCKAVNSLGEATCTAELIV 1848
             +Y+C A N  G A    EL V
Sbjct: 1043 GRYSCVAENLAGRAERKFELSV 1064



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 19/74 (25%), Positives = 35/74 (47%), Gaps = 3/74 (4%)

Query: 1778 DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSL 1837
            +C +E  P P++ W +D   ++E  H Q  + E G   L +  +   D   Y+C A N+ 
Sbjct: 2320 ECSVEAEPAPKITWHRDGIVLQEDAHTQ--FPERGR-FLQLQALSTADSGDYSCTARNAA 2376

Query: 1838 GEATCTAELIVETM 1851
            G  +    + + T+
Sbjct: 2377 GSTSVAFRVEIHTV 2390



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 5/102 (4%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1815
            V P F+    D  +  G      C   G P P + W  +D+ + E        ++DG  +
Sbjct: 2845 VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS-----EQDGGST 2899

Query: 1816 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1857
            L  + V  +D   Y C A N +G     + + V+     +GE
Sbjct: 2900 LQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGE 2941



 Score = 36.2 bits (82), Expect = 0.31
 Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 1/71 (1%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+  +  R  C   G P P ++W KD   +  +    +     G   L ++     D  +
Sbjct: 707  VLVNTPVRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRV-LTLASARASDSGR 765

Query: 1829 YTCKAVNSLGE 1839
            Y+C AV+++GE
Sbjct: 766  YSCVAVSAVGE 776



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 32/153 (20%), Positives = 55/153 (35%), Gaps = 19/153 (12%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K GN V            +G  G +   G     L + +       S   + AV E++
Sbjct: 729  WLKDGNPVSP----------AGTPGLQVFPGGRVLTLASARASDSGRYSCVAVSAVGEDR 778

Query: 1754 P------HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
                   H+ P       ++ VV   +   +C+    P P + W+KD + +       + 
Sbjct: 779  QDVVLQVHMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLS 838

Query: 1808 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
             D+     L +      D   YTC+A+N  G +
Sbjct: 839  ADK---ALLQVDRADVWDAGHYTCEALNQAGHS 868



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 5/100 (5%)

Query: 1236 MPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1292
            +PPQI    + P    V       L    TG  P T TW +  + +     ++++N   G
Sbjct: 972  VPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQ--G 1029

Query: 1293 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1332
              L +  A+  H G Y+ + EN  G  + +  L+V+  P+
Sbjct: 1030 QSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPE 1069



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 33/124 (26%), Positives = 51/124 (41%), Gaps = 15/124 (12%)

Query: 1106 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1165
            ++ +  G  + L C     P   I W  +G+ L  T+    S+   +  V        D 
Sbjct: 2222 ELSLTPGAPMELLCDAQGTPQPNITWHKDGQAL--TRLENNSRATRVLRV-------RDA 2272

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1225
            GLY C+A++ AG  E S +V V   P     + P          L  VL    + +V+ +
Sbjct: 2273 GLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQL--VL----ECSVEAE 2326

Query: 1226 PAPK 1229
            PAPK
Sbjct: 2327 PAPK 2330



 Score = 34.7 bits (78), Expect = 0.89
 Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 3/70 (4%)

Query: 1769 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1828
            V+E ++   +C   G P P+V WFK  Q +  S    +    DG   L I      D   
Sbjct: 615  VLENASVTLECLASGVPPPDVSWFKGHQPV--SSWMGVTVSVDGRV-LRIEQAQLSDAGS 671

Query: 1829 YTCKAVNSLG 1838
            Y C A N  G
Sbjct: 672  YRCVASNVAG 681



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 59/265 (22%), Positives = 90/265 (33%), Gaps = 65/265 (24%)

Query: 1105 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPE 1163
            Q+V    G  + LQC  S  P   + WT + +  L     + + ++G +  ++       
Sbjct: 134  QEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSHV--G 191

Query: 1164 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1223
            D G Y+CVA + AGQ     Q+ V  AP                   P + G+     V 
Sbjct: 192  DEGRYQCVAFSPAGQQARDFQLRV-HAP-------------------PTIWGSNETGEV- 230

Query: 1224 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1283
                      A M   ++Q              L  +  G      TW K    +  S  
Sbjct: 231  ----------AVMEDHLVQ--------------LLCEARGVPTPNITWFKDGALLPTS-- 264

Query: 1284 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------------ 1331
             KV  +  G +L +  A+    G YT    N +G+ +    L V   P            
Sbjct: 265  TKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVV 324

Query: 1332 DPPAGTPCASDIRS---SSLTLSWY 1353
               AG P A +  +    S TLSW+
Sbjct: 325  KAVAGRPVALECVARGHPSPTLSWH 349



 Score = 33.5 bits (75), Expect = 2.0
 Identities = 23/93 (24%), Positives = 37/93 (39%), Gaps = 1/93 (1%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1826
            L V EG   R  C+  G P P++ W KD Q +       + +       L +       +
Sbjct: 890  LTVREGHPTRLSCECRGVPFPKISWRKDGQPL-PGEGAGLQHVSAVGRLLYLGQAQLAQE 948

Query: 1827 AKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1859
              YTC+  N +G ++   +L V    +  G  E
Sbjct: 949  GTYTCECSNVVGNSSQDLQLEVHVPPQIAGPRE 981



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 5/85 (5%)

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+  G P P + WF+ ++ +      +  Y   G   L ++     D   Y+C A N  G
Sbjct: 1092 CEAMGIPPPAIRWFRGEEPVSPG---EDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAG 1148

Query: 1839 EATCTAELIVETMEEGEGEGEEEEE 1863
            EA       VE +     E E+ EE
Sbjct: 1149 EA--RRNFSVEVLVPPSIENEDLEE 1171



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 3/84 (3%)

Query: 1755 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1814
            H  P        + V     A   C+ +G P P V W KD   + + R  + +   +G  
Sbjct: 2388 HTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPL-DPRSPRFEILPEG-- 2444

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLG 1838
            SL I  V   D   Y C A NS G
Sbjct: 2445 SLRIQPVLAQDAGHYLCLASNSAG 2468



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/101 (25%), Positives = 41/101 (40%), Gaps = 12/101 (11%)

Query: 1751 EEKPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY 1808
            +  P VKP  S  + + + EV+        C+  G P P + W K+  ++      Q+  
Sbjct: 2663 QASPVVKPLPSVVRAVAEEEVL------LPCEASGIPRPTITWQKEGLNVATGVSTQVL- 2715

Query: 1809 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
                   L I+    +D   Y C A NS G A     L+V+
Sbjct: 2716 ---PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2753



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 27/130 (20%), Positives = 49/130 (37%), Gaps = 5/130 (3%)

Query: 1719 RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFD 1778
            R  S G  +S L +    +     +A L+   E +   +   ++ +  +  + G      
Sbjct: 371  RLESPGEASSGLYS--CVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQVTTIVGQPLELP 428

Query: 1779 CKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1838
            C+  G P P + W ++ +   E    Q+        +L I  V  D    + C+A N  G
Sbjct: 429  CQASGSPVPTIQWLQNGRPAEELAGVQV---ASQGTTLHIDHVELDHSGLFACQATNEAG 485

Query: 1839 EATCTAELIV 1848
             A    E+ V
Sbjct: 486  TAGAEVEVSV 495



 Score = 31.6 bits (70), Expect = 7.6
 Identities = 22/71 (30%), Positives = 28/71 (39%), Gaps = 3/71 (4%)

Query: 1770 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1829
            V GS     C + G P P V W KD   +  S    +     G   L +S +       Y
Sbjct: 1855 VAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGV-VSRGGR--LQLSRLQPAQAGTY 1911

Query: 1830 TCKAVNSLGEA 1840
            TC A N+  EA
Sbjct: 1912 TCVAENTQAEA 1922



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 1767 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD-D 1825
            ++ V G     +C   G+P P + W  +   + ES   +++ D     S++  +  G+  
Sbjct: 324  VKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDG----SVLRLESPGEAS 379

Query: 1826 DAKYTCKAVNSLGEATCTAELIVETMEE---GEGEGE 1859
               Y+C A +  GEA     + V+   +    EG G+
Sbjct: 380  SGLYSCVASSPAGEAVLQYSVEVQVPPQLLVAEGLGQ 416


>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
            sapiens]
          Length = 473

 Score =  158 bits (399), Expect = 5e-38
 Identities = 99/324 (30%), Positives = 156/324 (48%), Gaps = 56/324 (17%)

Query: 1460 VSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHP 1519
            +SDF+++E  LG G    V+R  +K T+K +A K  K     +K+ +R EI ++  L HP
Sbjct: 42   LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK--KTVDKKIVRTEIGVLLRLSHP 99

Query: 1520 KLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQ 1579
             +++  + FE    I +VLE+V+GGELF+RI+++ +  +ER+    ++QI E V Y+H+ 
Sbjct: 100  NIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY-YSERDAADAVKQILEAVAYLHEN 158

Query: 1580 GIVHLDLKPENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI 1638
            GIVH DLKPEN++         +K+ DFGL++ +E+   +K + GTP + APE++     
Sbjct: 159  GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218

Query: 1639 GYATDMWSIGVICYIL-------------------------------------------- 1654
            G   DMWS+G+I YIL                                            
Sbjct: 219  GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278

Query: 1655 --------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGR 1706
                     RL   Q LQHPW+     N      ++ +++++ ARRK +    AV A  R
Sbjct: 279  KLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 338

Query: 1707 LSSMAMISGLSGRKSSTGSPTSPL 1730
            L S +   G            SP+
Sbjct: 339  LGSASSSHGSIQESHKASRDPSPI 362


>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
            sapiens]
          Length = 370

 Score =  158 bits (399), Expect = 5e-38
 Identities = 93/316 (29%), Positives = 158/316 (50%), Gaps = 55/316 (17%)

Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKE-NIRQEISIMNCL 1516
            + + D YD  + LG+G F +V    +K+T+K+ A K     + + KE ++  EI++++ +
Sbjct: 14   EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKI 73

Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576
             HP +V   D +E   ++ +++++VSGGELF+RI+++ F  TER+  + + Q+ + V+Y+
Sbjct: 74   KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGF-YTERDASRLIFQVLDAVKYL 132

Query: 1577 HKQGIVHLDLKPENIMCVN-KTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
            H  GIVH DLKPEN++  +    ++I + DFGL++  +    L    GTP +VAPEV+  
Sbjct: 133  HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQ 192

Query: 1636 EPIGYATDMWSIGVICYIL----------------------------------------- 1654
            +P   A D WSIGVI YIL                                         
Sbjct: 193  KPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252

Query: 1655 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1703
                       R  C Q LQHPW+  DT  +    +   +++KK  A+ KW++  NA   
Sbjct: 253  IRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAV 312

Query: 1704 IGRLSSMAMISGLSGR 1719
            +  +  + + +   G+
Sbjct: 313  VRHMRKLQLGTSQEGQ 328


>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
            [Homo sapiens]
          Length = 357

 Score =  154 bits (390), Expect = 6e-37
 Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 55/325 (16%)

Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516
            + +   ++ +E LG+G F +V    EK T K++A K     + K KE+ I  EI+++  +
Sbjct: 17   EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76

Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576
             H  +V   D +E   ++ +V+++VSGGELF+RI+++ F  TE++    +RQ+ + V Y+
Sbjct: 77   KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135

Query: 1577 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
            H+ GIVH DLKPEN++  ++   ++I + DFGL++       +    GTP +VAPEV+  
Sbjct: 136  HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195

Query: 1636 EPIGYATDMWSIGVICYIL----------------------------------------- 1654
            +P   A D WSIGVI YIL                                         
Sbjct: 196  KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255

Query: 1655 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1703
                       R  C Q  +HPW+  DT  N    +    +++K  A+ KW++  NA   
Sbjct: 256  IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315

Query: 1704 IGRLSSMAMISGLSGRKSSTGSPTS 1728
            +  +  + + S L    +S  S  S
Sbjct: 316  VRHMRKLHLGSSLDSSNASVSSSLS 340


>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2
            [Homo sapiens]
          Length = 385

 Score =  154 bits (390), Expect = 6e-37
 Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 55/325 (16%)

Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1516
            + +   ++ +E LG+G F +V    EK T K++A K     + K KE+ I  EI+++  +
Sbjct: 17   EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76

Query: 1517 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1576
             H  +V   D +E   ++ +V+++VSGGELF+RI+++ F  TE++    +RQ+ + V Y+
Sbjct: 77   KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135

Query: 1577 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1635
            H+ GIVH DLKPEN++  ++   ++I + DFGL++       +    GTP +VAPEV+  
Sbjct: 136  HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195

Query: 1636 EPIGYATDMWSIGVICYIL----------------------------------------- 1654
            +P   A D WSIGVI YIL                                         
Sbjct: 196  KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255

Query: 1655 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1703
                       R  C Q  +HPW+  DT  N    +    +++K  A+ KW++  NA   
Sbjct: 256  IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315

Query: 1704 IGRLSSMAMISGLSGRKSSTGSPTS 1728
            +  +  + + S L    +S  S  S
Sbjct: 316  VRHMRKLHLGSSLDSSNASVSSSLS 340


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score =  152 bits (385), Expect = 2e-36
 Identities = 114/400 (28%), Positives = 172/400 (43%), Gaps = 40/400 (10%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
           P+  S+PQ  +V    TV F C   G PKPE+ W      +  +  S     D G+  L 
Sbjct: 246 PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGT--LM 303

Query: 474 LLKARTRDSGTYSCTASNAQGQLSCSWTLQVE-RLAVMEVAPSFSSVLKDCAVIEGQDFV 532
           +   +  D G Y C A N  G++    T +V  R       P+F    ++  V+ G+   
Sbjct: 304 IQNTQETDQGIYQCMAKNVAGEVK---TQEVTLRYFGSPARPTFVIQPQNTEVLVGESVT 360

Query: 533 LQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENAL 589
           L+CS  G P PRI+W    +   P+    +   +G   L+IQ+ +  D G Y C A N +
Sbjct: 361 LECSATGHPPPRISWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEYACSATNNI 418

Query: 590 GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
             V  +A++ V                      P F     D  V++G  V    +  GN
Sbjct: 419 DSVHATAFIIVQ-------------------ALPQFTVTPQDRVVIEGQTVDFQCEAKGN 459

Query: 650 PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
           PPP + W   G+++           GT   L I  V   D G Y C+A N  G  +  A 
Sbjct: 460 PPPVIAWTKGGSQLSVDRRHLVLSSGT---LRISGVALHDQGQYECQAVNIIGSQKVVAH 516

Query: 710 LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
           LTVQ       P F S P   T  +G +V + C+  G+P P + W +DG  +  ++G F 
Sbjct: 517 LTVQ---PRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQV-TESGKFH 572

Query: 770 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
           +  + + F L +  V P  AG+YE + +N +G  S  + L
Sbjct: 573 I--SPEGF-LTINDVGPADAGRYECVARNTIGSASVSMVL 609



 Score =  123 bits (308), Expect = 2e-27
 Identities = 85/325 (26%), Positives = 130/325 (40%), Gaps = 29/325 (8%)

Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
           +++V  +   + + +      A P F  +PQ+ EV   ++V   C  +G P P ++W   
Sbjct: 319 AKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRG 378

Query: 451 GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
                  +  + +    G +   +++    DSG Y+C+A+N    +  +  + V+ L   
Sbjct: 379 DRTPLPVDPRVNITPSGGLYIQNVVQG---DSGEYACSATNNIDSVHATAFIIVQAL--- 432

Query: 511 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570
              P F+   +D  VIEGQ    QC  +G P P I W   G  +   R         L I
Sbjct: 433 ---PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRI 489

Query: 571 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
                 D G Y C A N +G     A +TV  +                   P+F    S
Sbjct: 490 SGVALHDQGQYECQAVNIIGSQKVVAHLTVQPR-----------------VTPVFASIPS 532

Query: 631 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
           D  V  G+ V +     G P P + W  +G ++ ES  FH    G    L I +V P D 
Sbjct: 533 DTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG---FLTINDVGPADA 589

Query: 691 GTYTCEAWNSAGEVRTQAVLTVQEP 715
           G Y C A N+ G      VL+V  P
Sbjct: 590 GRYECVARNTIGSASVSMVLSVNVP 614



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 82/279 (29%), Positives = 117/279 (41%), Gaps = 27/279 (9%)

Query: 344 SITLQ-AARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK----- 397
           S+TL+ +A   P PR     +    G+    P  PR    P+   GL  Q+VV       
Sbjct: 358 SVTLECSATGHPPPR-----ISWTRGDRTPLPVDPRVNITPSG--GLYIQNVVQGDSGEY 410

Query: 398 AANRRIPMEGQRDSAF------PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEG 451
           A +    ++    +AF      P+F   PQ + V E QTV F+CE  G P P +AW   G
Sbjct: 411 ACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 470

Query: 452 TPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME 511
           + +      + +     S  L +      D G Y C A N  G       L V+      
Sbjct: 471 SQLSVDRRHLVL----SSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQP----R 522

Query: 512 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQ 571
           V P F+S+  D  V  G +  L CS +G P P ITW  +G  +  +     +    L I 
Sbjct: 523 VTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTIN 582

Query: 572 DALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
           D  P D G Y C+A N +G  S S  ++V+    SR  +
Sbjct: 583 DVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGD 621



 Score = 82.4 bits (202), Expect = 4e-15
 Identities = 60/218 (27%), Positives = 93/218 (42%), Gaps = 39/218 (17%)

Query: 33  PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
           P F + P++  + EG T  F+   +G P P + W + G  ++   R L    +  + +L 
Sbjct: 433 PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHL----VLSSGTLR 488

Query: 93  IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
           I  V   D+G+Y C+A N  G+++V   LTV         QP V+               
Sbjct: 489 ISGVALHDQGQYECQAVNIIGSQKVVAHLTV---------QPRVT--------------- 524

Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
                   P FA+      V+ G   +  C   G P+P +TW K  V +  S +  +S +
Sbjct: 525 --------PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPE 576

Query: 213 NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
                L I+ V   D G Y C+  N  G AS+S  LS+
Sbjct: 577 G---FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 611



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 62/227 (27%), Positives = 90/227 (39%), Gaps = 42/227 (18%)

Query: 31  EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI---TSGGRFLLDCGIRG 87
           E P     P++  +  G T  F  R  G P+P++ W RN   +   T     LLD G   
Sbjct: 244 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG--- 300

Query: 88  TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
             +L+I    E D+G Y C A N +G  + T E+T+                    F +P
Sbjct: 301 --TLMIQNTQETDQGIYQCMAKNVAGEVK-TQEVTLR------------------YFGSP 339

Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN-VPLQPSAR 206
           A            P F  +     V  G+     C  TG P P+++W +G+  PL    R
Sbjct: 340 A-----------RPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPR 388

Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
           V+++   G   L I  V Q D G Y C   N       +A + +Q L
Sbjct: 389 VNITPSGG---LYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQAL 432



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 4/108 (3%)

Query: 33  PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
           P F   P +  ++ GA  +     +G PEP +TW+++G  +T  G+F     I     L 
Sbjct: 525 PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKF----HISPEGFLT 580

Query: 93  IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
           I+ V   D G+Y C A N  G+  V++ L+V      + G P V+ ++
Sbjct: 581 INDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSI 628



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 4/96 (4%)

Query: 1753 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
            +P V P F+    D  V  G+  +  C  +G P+P + W KD   + ES  F I  +   
Sbjct: 520  QPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEG-- 577

Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
               L I+DV   D  +Y C A N++G A+ +  L V
Sbjct: 578  --FLTINDVGPADAGRYECVARNTIGSASVSMVLSV 611



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 67/291 (23%), Positives = 104/291 (35%), Gaps = 66/291 (22%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK--TLKTTKFIILSQEGSLCSV 1155
            P    + QD  V  G  +   C+   +P   IIW  N    ++KT   + L  +G+L   
Sbjct: 246  PRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTL--- 302

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD--DAPA-------SENTKAPEMKSRRP 1206
             I+     D+G+Y+C+AKN AG+ +   +VT+    +PA        +NT+    +S   
Sbjct: 303  MIQNTQETDQGIYQCMAKNVAGEVKTQ-EVTLRYFGSPARPTFVIQPQNTEVLVGESVTL 361

Query: 1207 KSSL-----PPVLGTESDATVKKKPAPKTPPKAAMP------------------------ 1237
            + S      P +  T  D T    P P  P     P                        
Sbjct: 362  ECSATGHPPPRISWTRGDRT----PLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 417

Query: 1238 ---------------PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1282
                           PQ    P+D+ V  G++V+   +  G  P    W K   Q+    
Sbjct: 418  IDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDR 477

Query: 1283 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
               V +S     L I        G Y     N +GS++   +LTV  +  P
Sbjct: 478  RHLVLSS---GTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 525



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 6/93 (6%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1816
            P F+ T +D  V+EG    F C+ +G P P + W K    +  + RH  +      + +L
Sbjct: 433  PQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVL-----SSGTL 487

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
             IS V   D  +Y C+AVN +G     A L V+
Sbjct: 488  RISGVALHDQGQYECQAVNIIGSQKVVAHLTVQ 520



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 2/89 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            EE    +P  +   +D +V  G+   F C+ EG P PE++W +++  +      +++  +
Sbjct: 239  EELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLD 298

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGE 1839
            DG  +L+I +    D   Y C A N  GE
Sbjct: 299  DG--TLMIQNTQETDQGIYQCMAKNVAGE 325



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 30/98 (30%), Positives = 42/98 (42%), Gaps = 3/98 (3%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P F     D  V  G  + L C    +P   I W  +G  +  +    +S EG L   +I
Sbjct: 525  PVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFL---TI 581

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
                P D G Y+CVA+N  G A  S  ++V+    S N
Sbjct: 582  NDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRN 619



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 35/114 (30%), Positives = 54/114 (47%), Gaps = 4/114 (3%)

Query: 705 RTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD 764
           R+ A +T +E +   +P   S+P+    + G +V  +C   G+P P + WLR+   L   
Sbjct: 231 RSVATITPEELNC-ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMK 289

Query: 765 TGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ-VSLMLQNSSAR 817
           T     L   D  TL+++  Q    G Y+ + KN  GE   Q V+L    S AR
Sbjct: 290 TD--SRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPAR 341



 Score = 44.7 bits (104), Expect = 9e-04
 Identities = 65/296 (21%), Positives = 100/296 (33%), Gaps = 56/296 (18%)

Query: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT-L 1138
            G   T +   R       P F  + Q+  V  G+ + L+C  +  PP  I WT   +T L
Sbjct: 324  GEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPL 383

Query: 1139 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1198
                 + ++  G L    I+  +  D G Y C A N+      +  + V   P  + T  
Sbjct: 384  PVDPRVNITPSGGL---YIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALP--QFTVT 438

Query: 1199 PEMK----------SRRPKSSLPPVL-----GTE----------SDATVK---------- 1223
            P+ +              K + PPV+     G++          S  T++          
Sbjct: 439  PQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQG 498

Query: 1224 ------------KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1271
                        +K       +  + P     P D  V  G +V+L     G      TW
Sbjct: 499  QYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITW 558

Query: 1272 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
             K   Q+ ES   K   S  G  LTI        G Y  +  N +GS    + L+V
Sbjct: 559  NKDGVQVTESG--KFHISPEGF-LTINDVGPADAGRYECVARNTIGSASVSMVLSV 611



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 11/101 (10%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS- 1815
            +P F    ++ EV+ G +   +C   G+P P + W + D++        +  D   N + 
Sbjct: 341  RPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRT-------PLPVDPRVNITP 393

Query: 1816 ---LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1853
               L I +V   D  +Y C A N++     TA +IV+ + +
Sbjct: 394  SGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQ 434


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score =  151 bits (381), Expect = 7e-36
 Identities = 88/298 (29%), Positives = 148/298 (49%), Gaps = 53/298 (17%)

Query: 1458 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1517
            +K+  FY+++E +G G FG V R+  K  + + A KF    S    +  R+   I+  L 
Sbjct: 6462 RKLHSFYEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRER-DILAALS 6520

Query: 1518 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1577
            HP +   +D FE +  ++++LE+ S  EL +R+  +   +TE E   Y++Q+ EG+ Y+H
Sbjct: 6521 HPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGV-VTEAEVKVYIQQLVEGLHYLH 6579

Query: 1578 KQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEP 1637
              G++HLD+KP NI+ V+     IK+ DFG A+ +  A      +G+PEFV+PE+I   P
Sbjct: 6580 SHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNP 6639

Query: 1638 IGYATDMWSIGVICY-----------------ILNRLD---------------------- 1658
            +  A+D+W++GVI Y                 +LN L+                      
Sbjct: 6640 VSEASDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIK 6699

Query: 1659 ------------CTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAI 1704
                          QCL HPW +K     EA  ++  ++K  +AR +WQ++  + ++I
Sbjct: 6700 ATLQRAPQARPSAAQCLSHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSI 6757



 Score =  143 bits (361), Expect = 1e-33
 Identities = 156/641 (24%), Positives = 245/641 (38%), Gaps = 96/641 (14%)

Query: 129  KQLGQPVVSKTLGDRFSA-PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGR 187
            K LG P + K      +A    + R  +  +  P F+   G    + G   R  C +  +
Sbjct: 4865 KDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASK 4924

Query: 188  PQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
               +  WLK  V L       + +  +G   L I G+++ D G YTC V N  G+ + SA
Sbjct: 4925 ADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984

Query: 247  ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP 306
             + + G +S   S    +     D  +     + +  +  S    +  +   S   G + 
Sbjct: 4985 CVVVSGSESEAES---SSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAE 5041

Query: 307  P-----WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
            P     W    + +     + E+  ++ +   +   +  T   I ++   V+  PR   +
Sbjct: 5042 PEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFATLG-IGVEIKLVEQGPRRVEM 5100

Query: 362  GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
             +       ++ PAP  P   P   P L + D                  A P F ++ Q
Sbjct: 5101 CI------SKETPAPVVP---PEPLPSLLTSD------------------AAPVFLTELQ 5133

Query: 422  SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481
            +QEV++   V F C V+G P P V WF +G  +   +  +   +  G H L +      D
Sbjct: 5134 NQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPAD 5193

Query: 482  SGTYSCTASNAQGQLSCSWTLQVERLAV--------MEVAPSFSSV-------------- 519
             G Y C A N+ G  S    L+V+  +          E +  FS+               
Sbjct: 5194 MGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTEST 5253

Query: 520  ------------LKDCAVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQ---YARSTCEA 563
                        L+D  V  G      Q  V+G P PR+ W  +GQP+    + R T + 
Sbjct: 5254 TDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKK 5313

Query: 564  GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAP 617
             +  L I     ED G Y     NA+G    SA + V       EK +S   E L+P   
Sbjct: 5314 ILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVP--- 5370

Query: 618  SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI------QESEDFHF 671
                 P  L+  +  KV  GS +T +V+V G P P V WL    E        ++  +  
Sbjct: 5371 -----PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTV 5425

Query: 672  EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 712
                 QHSL + +V  +  GTYTC A N+AG+    A L V
Sbjct: 5426 ASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466



 Score =  119 bits (298), Expect = 3e-26
 Identities = 106/376 (28%), Positives = 142/376 (37%), Gaps = 61/376 (16%)

Query: 414 PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGS-IEVYEDAGSHYL 472
           P F  +P S  V+E     FRC V G P+P V+W  +G  +   +G  + V E   +  L
Sbjct: 110 PHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASAL 169

Query: 473 CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV----------------------- 509
            +  AR RD GTY   A N  G  S +  L V+  A                        
Sbjct: 170 RIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREA 229

Query: 510 --MEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 565
              E AP+   S+  + C V EG+   L C V G P P   W  +GQ +   R       
Sbjct: 230 MRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYED 289

Query: 566 AE----LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 621
           A+    L I      D G YTC A N +GQ   S  V V E                 P 
Sbjct: 290 AQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVRE-----------------PA 332

Query: 622 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 681
            P F + L DL+V +    T   +V   P  E  W      +  S  +  E+ GT+  L 
Sbjct: 333 VP-FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLT 390

Query: 682 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
           ++ V  +D   Y CE    +   RT A L VQ             PR     +G + +  
Sbjct: 391 VRNVSADDDAVYICETPEGS---RTVAELAVQ------GNLLRKLPRKTAVRVGDTAMF- 440

Query: 742 CAIAGDPFPTVHWLRD 757
           C     P   VHWLR+
Sbjct: 441 CVELAVPVGPVHWLRN 456



 Score =  119 bits (297), Expect = 4e-26
 Identities = 93/337 (27%), Positives = 143/337 (42%), Gaps = 32/337 (9%)

Query: 405 MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVY 464
           M+  + S  P+F ++P++  V   +     C++ G P P+V+W  +  PV        + 
Sbjct: 1   MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPV-AAGARFRLA 59

Query: 465 EDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVE-RLAVMEVAPSFSSVLKDC 523
           +D   + L +L     DSG Y C A NA G+   +  LQV+   A  E AP F       
Sbjct: 60  QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSI 119

Query: 524 AVIEGQDFVLQCSVRGTPVPRITWLLN----GQPIQYARSTCEAGVAE-LHIQDALPEDH 578
            V EG +   +C V G+P P ++W  +    G+P        E G A  L I+ A P D 
Sbjct: 120 RVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDG 179

Query: 579 GTYTCLAENALGQVSCSAWVTVHEKKSS------------------RKSEYLLPVAPSKP 620
           GTY   AEN LG  S +A + V    +                   R+       AP+ P
Sbjct: 180 GTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASP 239

Query: 621 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 680
            +     G     V +G    ++  V+G P PE +W  +G  + E    H      Q + 
Sbjct: 240 PS----TGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR-HVVYEDAQENF 294

Query: 681 CIQEVF--PEDTGTYTCEAWNSAGEVRTQAVLTVQEP 715
            ++ +F    D G YTC A N  G+  +  ++ V+EP
Sbjct: 295 VLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREP 331



 Score =  117 bits (294), Expect = 8e-26
 Identities = 123/460 (26%), Positives = 197/460 (42%), Gaps = 54/460 (11%)

Query: 1215 GTESDATVKKKPAPKTPPKAAMP-----PQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1269
            G E +   +KKP   +   + +      P  ++   D+ V  G+SV L  +V+       
Sbjct: 7435 GLEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQA 7494

Query: 1270 TWMKFRKQIQESEHMKVENS-ENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT-V 1327
            TW K    ++ S  + +  + +N   LTIL    E  G YT  V N LG+    V  T V
Sbjct: 7495 TWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGT----VTTTGV 7550

Query: 1328 VDKPDPPAGTPCAS--DIRSSSLTLSWYG-SSYDGGSAVQSYSIEIWDSANKTWKELAT- 1383
            + K + P+ +PC    ++ +  + L W    SY   + +   S+E       +W  LA+ 
Sbjct: 7551 LRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLE-----GGSWTTLASD 7605

Query: 1384 ----CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1439
                C  TS     L     Y FR   ++  G    S  SE   +G  P     E E S 
Sbjct: 7606 IFDCCYLTS----KLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG-PSHLASEEE-SQ 7659

Query: 1440 DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYS 1499
                +P    +T    T+            +  G+F  V +  EK + +  A K    Y 
Sbjct: 7660 GRSAQPLPSTKTFAFQTQ------------IQRGRFSVVRQCWEKASGRALAAKIIP-YH 7706

Query: 1500 AKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTE 1559
             K+K  + +E   +  L HP L Q   A+    ++V++LE+ SG EL    + E    +E
Sbjct: 7707 PKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLP-CLAERASYSE 7765

Query: 1560 RECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLK 1619
             E   Y+ Q+    +Y+H Q I+HLDL+ EN++        +K++D G A+ L      K
Sbjct: 7766 SEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEY--NLLKVVDLGNAQSLSQE---K 7820

Query: 1620 VLFGTP-----EFVAPEVINYEPIGYATDMWSIGVICYIL 1654
            VL         E +APE++  +     TD+W+IGV  +I+
Sbjct: 7821 VLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIM 7860



 Score =  117 bits (292), Expect = 1e-25
 Identities = 287/1336 (21%), Positives = 478/1336 (35%), Gaps = 229/1336 (17%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            P KF   L      EG      C+++      V W KG   L+   R  + ++     L+
Sbjct: 3449 PAKFTEGLRNEEAVEGATAMLWCELS--KVAPVEWRKGPENLRDGDRYILRQEGTRCELQ 3506

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            I G+   D G Y C+     G+   SA L+I+ L +    F+ + K  N + R+  T V+
Sbjct: 3507 ICGLAMADAGEYLCVC----GQERTSATLTIRALPAR---FIEDVK--NQEAREGATAVL 3557

Query: 280  SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVL- 338
              E  L+S  A  + +  S   R G          +   + +  +  D   T   + V  
Sbjct: 3558 QCE--LNSA-APVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMAD---TGEYSCVCG 3611

Query: 339  -QKTSSSITLQAARVQ------PEPRAPG--------LGVLSP----SGEERKRPAPPRP 379
             ++TS+ +T++A  ++       E    G        L  ++P     G E  R      
Sbjct: 3612 QERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPVEWWKGHETLRDGDRHS 3671

Query: 380  ATFPTRQPGLGSQDVVSKAANRRIPMEG-QRDSAFPKFESKP-------QSQEVKENQTV 431
                  +  L  + +V++ A   + M G +R SA     + P       +++E  E  T 
Sbjct: 3672 LRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPSKFIEGLRNEEATEGDTA 3731

Query: 432  KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL------CLLKAR---TRDS 482
               CE+S           +  PV  ++G  E   D   H L      C L+ R     D+
Sbjct: 3732 TLWCELS-----------KAAPVEWRKGH-ETLRDGDRHSLRQDGSRCELQIRGLAVVDA 3779

Query: 483  GTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPV 542
            G YSC      GQ   S TL V  L        F   +K+    EG   VLQC +  +  
Sbjct: 3780 GEYSCVC----GQERTSATLTVRALPAR-----FIEDVKNQEAREGATAVLQCEL--SKA 3828

Query: 543  PRITWLLNGQPIQYAR--STCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 599
              + W    + ++     S  + G   EL I      D G Y+C+     GQ   SA +T
Sbjct: 3829 APVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLT 3884

Query: 600  VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
            V               AP     P+F + L  L+  +GS  T+  ++S  P   V+W   
Sbjct: 3885 VR--------------APQ----PVFREPLQSLQAEEGSTATLQCELS-EPTATVVWSKG 3925

Query: 660  GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 719
            G ++Q +       +G    L +Q++  EDTG YTC    + G   T A LTV       
Sbjct: 3926 GLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTC----TCGSQATSATLTV----TAA 3977

Query: 720  QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 779
               F+ + +      G +  + C ++     +V W R G         ++++Q+     L
Sbjct: 3978 PVRFLRELQHQEVDEGGTAHLCCELS-RAGASVEW-RKGSLQLFPCAKYQMVQDGAAAEL 4035

Query: 780  VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 839
            +++ V+   AG Y     +     S  V +       R     +E      LC     A+
Sbjct: 4036 LVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAE 4095

Query: 840  GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR-----------QHTEEAIR 888
             G   ++  L+ G         E       R +L  ++E +           Q T  ++R
Sbjct: 4096 SGAVVQW--LKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYACVTGGQKTAASLR 4153

Query: 889  QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSP 948
              E E    R L+  +V+              E ++F   + R     T  +   +    
Sbjct: 4154 VTEPEVTIVRGLVDAEVTAD------------EDVEFSCEVSR--AGATGVQWCLQGLPL 4199

Query: 949  QQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAV 1008
            Q  +   V  + G   T   + V P    T  F   LG        + SS+  T+ A  V
Sbjct: 4200 QSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFH--LG-------NHASSAQLTVRAPEV 4250

Query: 1009 ESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDEN-LKSASKEE- 1066
               +PL + Q       +   + A     +  A   E    +G      N +   + E+ 
Sbjct: 4251 TILEPLQDVQ-------LSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQG 4303

Query: 1067 ------LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1120
                  L K    D      H GT  +E + +        +  L++V   EG + L +CQ
Sbjct: 4304 TLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVR-GLENVEALEGGEALFECQ 4362

Query: 1121 VSSDPPATIIWTLNGKTLKTTK--FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1178
            +S    A   W L+ + + T++   ++  + G    + ++   P+D              
Sbjct: 4363 LSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQD-------------- 4408

Query: 1179 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1238
               SC+VT                       L   + T +  TV+               
Sbjct: 4409 ---SCRVTF----------------------LAGDMVTSAFLTVR-----------GWRL 4432

Query: 1239 QIIQFPEDQKVRAGESVELFGKVTGTQPI-TCTWMKFRKQIQ-ESEHMKVENSENGSKLT 1296
            +I++  ++  VRAG        ++   P+   +W      +Q +     V    +   L 
Sbjct: 4433 EILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALL 4492

Query: 1297 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1356
            + +A+  H G  T    + +    A   LTV+  PDPP      +   S ++TLSW    
Sbjct: 4493 LRSAQPHHAGEVTFACRDAV----ASARLTVLGLPDPPEDAEVVAR-SSHTVTLSWAAPM 4547

Query: 1357 YDGGSAVQSYSIEIWDSANKTWK---ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
             DGG  +  Y +E+ + A   W+   EL         V  L P   Y+FRV A+   G  
Sbjct: 4548 SDGGGGLCGYRVEVKEGATGQWRLCHELVP--GPECVVDGLAPGETYRFRVAAVGPVGAG 4605

Query: 1414 EPSQESELTTVGEKPE 1429
            EP    +   + E P+
Sbjct: 4606 EPVHLPQTVRLAEPPK 4621



 Score =  117 bits (292), Expect = 1e-25
 Identities = 117/500 (23%), Positives = 199/500 (39%), Gaps = 81/500 (16%)

Query: 26   SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
            ++P+   P F     +   + G T K   RV G P+P ++W+++G+ +      +L    
Sbjct: 6007 ALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDP 6066

Query: 86   RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
             G+ +L++ ++   D G+Y C A + +G                         TLG    
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGN----------------------CSTLG---- 6100

Query: 146  APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
                     I  + PP+F  K+      EG+  +F+C I G P PQ+ W K    L    
Sbjct: 6101 --------KILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGN 6152

Query: 206  RV-SVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG--LDSANRSFV 261
            +  ++SE ++G+ VL I   +++D+G+Y C +VN  G A  SAEL IQ   L +  +   
Sbjct: 6153 KFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212

Query: 262  RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
             +  A   D   E  +           E  +  K    P+  G            P    
Sbjct: 6213 EQLVAAVEDTTLERAD----------QEVTSVLKRLLGPKAPG------------PSTGD 6250

Query: 322  LESCKDSPRTAPQTPVLQKTSSSITLQAARVQP--EPRAPGLGVLSPSGEERKRPAPPRP 379
            L      PR A   P LQ+T S   +      P   PR P   +     +E +  A  + 
Sbjct: 6251 LTGPGPCPRGA---PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAIARAQE 6307

Query: 380  ATFPTRQ-----PGLGSQDVVSKAANRRIPMEGQRDSAFPKFE---SKPQSQEV------ 425
             T P R      PG G+ +++    +  +    QR   +   +   ++P S +V      
Sbjct: 6308 WTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIEDVQ 6367

Query: 426  -KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGT 484
             +   T +F   + G P+P V W+ +   +      +   ++  ++ L L    ++D+G 
Sbjct: 6368 AQTGGTAQFEAIIEGDPQPSVTWYKDSVQL-VDSTRLSQQQEGTTYSLVLRHVASKDAGV 6426

Query: 485  YSCTASNAQGQLSCSWTLQV 504
            Y+C A N  GQ+ C   L V
Sbjct: 6427 YTCLAQNTGGQVLCKAELLV 6446



 Score =  117 bits (292), Expect = 1e-25
 Identities = 118/442 (26%), Positives = 176/442 (39%), Gaps = 53/442 (11%)

Query: 414  PKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLC 473
            P FE +      +  +TVK  C V+G PKP ++W+ +G  V+     I + +  GS  L 
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 474  LLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVL 533
            L      DSG Y C A++A G  +CS   ++    +++V P F + ++    +EG+D   
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAG--NCSTLGKI----LVQVPPRFVNKVRASPFVEGEDAQF 6127

Query: 534  QCSVRGTPVPRITWLLNGQPIQYAR-----STCEAGVAELHIQDALPEDHGTYTCLAENA 588
             C++ G P P+I W  +G  +         S   +G+  L I+ A  ED G Y C   N 
Sbjct: 6128 TCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187

Query: 589  LGQVSCSAWVTVH----------------------------EKKSSRKSEYLLPVAPSKP 620
            LG    SA + +                             ++ +S     L P AP   
Sbjct: 6188 LGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLGPKAPGPS 6247

Query: 621  TAPIFLQGL----SDLKVMDGSQ--VTMTVQVSGNPP--PEVIWLHNGNEIQESEDFHFE 672
            T  +   G     +      GSQ  VT T +    PP  P+ + LH G E QE E     
Sbjct: 6248 TGDLTGPGPCPRGAPALQETGSQPPVTGTSEAPAVPPRVPQPL-LHEGPE-QEPEAIARA 6305

Query: 673  QRGTQHSLCIQEVFP-EDTGTYTCEAWNSAGEVRTQAVLTVQ--EPHDGTQPWFISKPRS 729
            Q  T         +P   TG    +  +      TQ   T Q  + H    P        
Sbjct: 6306 QEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTARPPSMQVTIED 6365

Query: 730  VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 789
            V A  G +      I GDP P+V W +D   L  D+      Q    ++LVL+ V    A
Sbjct: 6366 VQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLV-DSTRLSQQQEGTTYSLVLRHVASKDA 6424

Query: 790  GQYEILLKNRVGECSCQVSLML 811
            G Y  L +N  G+  C+  L++
Sbjct: 6425 GVYTCLAQNTGGQVLCKAELLV 6446



 Score =  112 bits (279), Expect = 4e-24
 Identities = 106/409 (25%), Positives = 170/409 (41%), Gaps = 51/409 (12%)

Query: 424  EVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
            +V+E  +  FRC +S      V WFL+ TP+   E +    +  G H L L +   +DSG
Sbjct: 3015 DVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSG 3074

Query: 484  TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
            T    A + +   +         L V E    FS  L D  + EG+D  L C      +P
Sbjct: 3075 TIYFEAGDQRASAA---------LRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIP 3125

Query: 544  RITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
             + W  +G+ ++     + + E   A+L I  A  +D G Y C A    G    S+ V V
Sbjct: 3126 -VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSSIVRV 3180

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
            H +          PV         F + L DL+V++G   T+   +S    P V W +  
Sbjct: 3181 HAR----------PVR--------FQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGN 3221

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
            N ++  + +   Q G    L ++ + P+D+G Y+C    S G+  T A LTV        
Sbjct: 3222 NVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTV----TALP 3273

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
              FI K R+  A+ G +  + C ++      V W R G    +D   + + Q+  +  L 
Sbjct: 3274 AQFIGKLRNKEATEGATATLRCELS--KAAPVEW-RKGSETLRDGDRYCLRQDGAMCELQ 3330

Query: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCE 829
            ++ +    A +Y  +     GE     SL ++   A  + R R   S E
Sbjct: 3331 IRGLAMVDAAEYSCV----CGEERTSASLTIRPMPAHFIGRLRHQESIE 3375



 Score =  112 bits (279), Expect = 4e-24
 Identities = 90/346 (26%), Positives = 141/346 (40%), Gaps = 43/346 (12%)

Query: 507  LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCE 562
            L   + AP F + L++  V +G      C V G P+P + W  +G+ ++    Y  +  +
Sbjct: 5119 LLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQ 5178

Query: 563  AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH-------------EKKSSRKS 609
             G  +L I   +P D G Y CLAEN++G  S  A + V              E  S   +
Sbjct: 5179 QGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSA 5238

Query: 610  EYLLPVAPSKPTA--------PIFLQGLSDLKVMDGSQVT-MTVQVSGNPPPEVIWLHNG 660
            +  L     + T         P  ++ L DL+V  G+++    ++V G P P + W  +G
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
              +  S       +   H+L I  V  ED+G Y     N+ G   + A L V+ P +  +
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEE 5358

Query: 721  ------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA-----LCK 763
                        P  + +        G S+  S  + G P PTVHWLR+        +  
Sbjct: 5359 KPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418

Query: 764  DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
            DT  + V  +    +LVL  V   H G Y  +  N  G+  C  SL
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASL 5464



 Score =  104 bits (259), Expect = 9e-22
 Identities = 133/567 (23%), Positives = 214/567 (37%), Gaps = 80/567 (14%)

Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
           P+F T+    VV  G+    SC+I G P PQV+W K   P+   AR  +++   +  L I
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
             +   D G Y C   N  G+A  +  L +                  +   ++  + + 
Sbjct: 70  LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA---------------EAACAEQAPHFLL 114

Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340
           + + +   E +  +  C   + GGSP  A +      R  +     D PR   +      
Sbjct: 115 RPTSIRVREGSEATFRC---RVGGSPRPAVSWSKDGRRLGE----PDGPRVRVEE---LG 164

Query: 341 TSSSITLQAARVQPEPRAPG---LGVLSPSGEERKRPA--PPRPATFPTRQPGLGSQDVV 395
            +S++ ++AAR    PR  G   +   +P G      A      A     +PG  +  ++
Sbjct: 165 EASALRIRAAR----PRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALL 220

Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR 455
           +    RR  M  +   A P   +  ++  V E +  +  C V+G PKPE  W  +G  V 
Sbjct: 221 AHLQRRREAMRAEGAPASPP-STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVT 279

Query: 456 RQEGSIEVYEDAGSHY-LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAP 514
                + VYEDA  ++ L +L  +  D G Y+CTASN  GQ     T     + V E A 
Sbjct: 280 EGRRHV-VYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQ-----TYSSVLVVVREPAV 333

Query: 515 SFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE------L 568
            F   L+D  V E +     C V   P     W      +    ++ + G+ E      L
Sbjct: 334 PFKKRLQDLEVREKESATFLCEV-PQPSTEAAWFKEETRLW---ASAKYGIEEEGTERRL 389

Query: 569 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 628
            +++   +D   Y C        V+  A      +K  RK+                   
Sbjct: 390 TVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTA------------------ 431

Query: 629 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 688
              ++V D +   + + V   P   V WL N  E+           GT+H+L I +   E
Sbjct: 432 ---VRVGDTAMFCVELAVPVGP---VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485

Query: 689 DTGTYTCEAWNSAGEVRTQAVLTVQEP 715
           D G    +    AG+ +T     V  P
Sbjct: 486 DVG----QVAFMAGDCQTSTQFCVSAP 508



 Score =  103 bits (256), Expect = 2e-21
 Identities = 84/337 (24%), Positives = 132/337 (39%), Gaps = 53/337 (15%)

Query: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELH 569
           AP F +  K   V  G+D  L C + G P P+++W  + QP+      R   +  +  L 
Sbjct: 9   APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68

Query: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 629
           I D    D G Y C A NA+G+   +  + V  +            A     AP FL   
Sbjct: 69  ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE------------AACAEQAPHFLLRP 116

Query: 630 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFP 687
           + ++V +GS+ T   +V G+P P V W  +G  + E +      E+ G   +L I+   P
Sbjct: 117 TSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARP 176

Query: 688 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL------------- 734
            D GTY   A N  G     A L V      T     S+P + TA+L             
Sbjct: 177 RDGGTYEVRAENPLGAASAAAALVVDSDAADT----ASRPGTSTAALLAHLQRRREAMRA 232

Query: 735 -------------------GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 775
                              G+   +SC + G+P P   W +DG+ + +   H      ++
Sbjct: 233 EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQE 292

Query: 776 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 812
            F L +   +    G Y     N VG+    V ++++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329



 Score =  100 bits (249), Expect = 1e-20
 Identities = 189/808 (23%), Positives = 308/808 (38%), Gaps = 116/808 (14%)

Query: 29   LTEAP-AFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
            +TE P +F  P +++   E      E  +   P   V W ++G  + +G    +    +G
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAI--AAQG 2217

Query: 88   TF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD-RFS 145
               SL I+     D+G Y C+A +     Q +  + V+G     + + V+++  G+ +F 
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRVLAEDAGEIQFV 2273

Query: 146  APAVETRPSIW-GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
            A   E+R  +   E P      L   +  E   G   C+++ R   QV W KG+  LQP 
Sbjct: 2274 AENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPG 2332

Query: 205  ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
             +  +      + L I  V+ +D   YTC     +G    SA+  ++      +S     
Sbjct: 2333 PKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVE-----EQSITIVR 2383

Query: 265  KATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324
               +  V +        E+ + S+         +  Q GG+       +    R     +
Sbjct: 2384 GLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGNV--GLEQEGTVHRLMLRRT 2441

Query: 325  CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSP-SGEERK--------RPA 375
            C  S  T P    + K+ SS  L  + +      P    L P +G E +        RPA
Sbjct: 2442 C--STMTGPVHFTVGKSRSSARLVVSDIPVVLTRP----LEPKTGRELQSVVLSCDFRPA 2495

Query: 376  PPRPATFPTRQPGLGSQ----DVVSKAANRRI----PMEG-----QRDSAFPKFESKPQS 422
            P     +    P   S+     +  + A  RI    P +      Q  SA    E   ++
Sbjct: 2496 PKAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEA 2555

Query: 423  QEV-----------KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHY 471
            +EV            E     F CE+S     EV W L G P+   +   E+      H 
Sbjct: 2556 REVTVTGPLQDAEATEEGWASFSCELSH-EDEEVEWSLNGMPL-YNDSFHEISHKGRRHT 2613

Query: 472  LCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDF 531
            L L   +  D+G    ++     ++S S  L+V    V+     F   L D +  E    
Sbjct: 2614 LVLKSIQRADAGIVRASSL----KVSTSARLEVRVKPVV-----FLKALDDLSAEERGTL 2664

Query: 532  VLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENA 588
             LQC V   P   + W  +G    P         AG   L + D  PED G YTC     
Sbjct: 2665 ALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----H 2719

Query: 589  LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSG 648
            +G     A V VH+          L V  +K         L  ++V++G   +    +S 
Sbjct: 2720 VGSEETRARVRVHD----------LHVGITK--------RLKTMEVLEGESCSFECVLSH 2761

Query: 649  NPPPE-VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
                +  +W   G  +  S  F   ++G ++ L ++E  P D G    E   S   + ++
Sbjct: 2762 ESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG----EVVFSVRGLTSK 2817

Query: 708  AVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAI--AGDPFPTVHWLRDGKALCKD 764
            A L V+E     +P  I KP      + G+ V + C +  AG P   VHWL+D KA+ K 
Sbjct: 2818 ASLIVRE-----RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP---VHWLKDRKAIRK- 2868

Query: 765  TGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
            +  ++V+    +  LV++      AG+Y
Sbjct: 2869 SQKYDVVCEGTMAMLVIRGASLKDAGEY 2896



 Score =  100 bits (248), Expect = 2e-20
 Identities = 166/761 (21%), Positives = 281/761 (36%), Gaps = 124/761 (16%)

Query: 37   LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
            L  R +  + GA A     V    + +VTW+++G+ ++S  +  ++  +  T  LV+   
Sbjct: 1355 LAHRKVQAEAGAIATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEA-VGCTRRLVVQQA 1412

Query: 97   HEEDRGKYTCEATNGSGARQVTVELTVEGS---FAKQLGQPVVSKTLGDRFSAPAVETRP 153
             + D G+Y+CEA    G ++++  L V      FAK+  QPV  +               
Sbjct: 1413 CQADTGEYSCEA----GGQRLSFSLDVAEPKVVFAKE--QPVHRE--------------- 1451

Query: 154  SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
                            V  + G     SC++  + Q +V W K    L  S++V +    
Sbjct: 1452 ----------------VQAQAGASTTLSCEVA-QAQTEVMWYKDGKKLSFSSKVRMEAVG 1494

Query: 214  GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRETKA---T 267
              + L +    Q   G Y+C     +G   +S  L +   + + +  +   RE +A   T
Sbjct: 1495 CTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGT 1550

Query: 268  NSDVRKEVTNV------------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQ 315
            ++ +  EV               +S  SK+  +EA   ++     + G +     + +  
Sbjct: 1551 SATLSCEVAQAQTEVTWYKDGKKLSSSSKV-RMEAVGCTRRLVVQEAGQADAGEYSCKAG 1609

Query: 316  PPR--------ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPS 367
              R        E K+   K+ P    +       S++++ + A+ Q E      G    S
Sbjct: 1610 DQRLSFHLHVAEPKVVFAKEQPAHR-EVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668

Query: 368  GEERKRPAPPRPATFPTRQPGLGSQDVVS-KAANRRIPMEGQRDSAFPKFESKPQSQE-- 424
              + +  A         +Q G       S +A  +R+          P+   +P  +E  
Sbjct: 1669 SSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERPCRREPL 1728

Query: 425  -VKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG 483
             VKE++ +     ++      V W  +G  +RR +   E      +H L +  A+  DS 
Sbjct: 1729 VVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRH-ETASQGDTHTLTVHGAQVLDSA 1787

Query: 484  TYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVP 543
             YSC    A+GQ    + +QVE     EVA  F  +L+      G    L C +      
Sbjct: 1788 IYSCRVG-AEGQ---DFPVQVE-----EVAAKFCRLLEPVCGELGGTVTLACEL-SPACA 1837

Query: 544  RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
             + W      ++  +      E  V  L +     ED G Y C                 
Sbjct: 1838 EVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEYVC----------------- 1880

Query: 601  HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
                 SR       +  S P    F+ GLS +   +G + T    VS +    V+W  +G
Sbjct: 1881 ----ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDG 1935

Query: 661  NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
              +Q SE F   Q G  HSL I ++  ED G  T EA  ++    + A L V+E      
Sbjct: 1936 ALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGAS----SSAALRVRE----AP 1987

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              F  K    T     SV +   +   P+P + W R+  AL
Sbjct: 1988 VLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATAL 2027



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 189/859 (22%), Positives = 303/859 (35%), Gaps = 167/859 (19%)

Query: 60   PEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
            P P++ W RN   +  G    +   G R    LV+H V   DRG + CE  +     ++T
Sbjct: 2014 PWPELRWTRNATALAPGKNVEIHAEGAR--HRLVLHNVGFADRGFFGCETPDDKTQAKLT 2071

Query: 119  VELT-----------------------------VEGSFAKQ-------------LGQPVV 136
            VE+                              V+GS+ +              +  P+ 
Sbjct: 2072 VEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMH 2131

Query: 137  SKTLGDR---------FSAPAVETRPS-IWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
            + TL            F A  V T    +  E P  F+  L  VV  E +     C+++ 
Sbjct: 2132 TLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELS- 2190

Query: 187  RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
            RP   V WLK  V L+    ++++ +   + L I+     D GVY C     +  A  SA
Sbjct: 2191 RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSA 2246

Query: 247  ELSIQGL------------DSANRSFVRETKATNSDVRKE---VTNVISKESKLDSLEAA 291
             + +QG             D+    FV E   + + +R +   VT V     K+ ++E  
Sbjct: 2247 SVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKI-AMEKH 2305

Query: 292  AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSP-RTAPQTPVLQKTSSSITLQAA 350
                 C   +      W   SQ   P   K E   D   R    + V  +   + T  A 
Sbjct: 2306 RGVLECQVSRASAQVRWFKGSQELQPGP-KYELVSDGLYRKLIISDVHAEDEDTYTCDAG 2364

Query: 351  RVQPEPR--APGLGVLSPSGEERKRPAPPRPATF------PTRQP--------------- 387
             V+   +       +    G +      P PA F      P+ +P               
Sbjct: 2365 DVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGN 2424

Query: 388  -GLGSQDVVSKAANRRI--PMEG--------QRDSA------FPKFESKPQSQEV-KENQ 429
             GL  +  V +   RR    M G         R SA       P   ++P   +  +E Q
Sbjct: 2425 VGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQ 2484

Query: 430  TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489
            +V   C+    PK  V W+ + TP+   E   ++  +     L +L+    D+G Y C A
Sbjct: 2485 SVVLSCDFRPAPKA-VQWYKDDTPLSPSE-KFKMSLEGQMAELRILRLMPADAGVYRCQA 2542

Query: 490  SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
             +A      S  + VE   V    P     L+D    E       C +       + W L
Sbjct: 2543 GSAHS----STEVTVEAREVTVTGP-----LQDAEATEEGWASFSCELSHED-EEVEWSL 2592

Query: 550  NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
            NG P+ Y  S  E           L         +   +  +VS SA + V  K      
Sbjct: 2593 NGMPL-YNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSLKVSTSARLEVRVK------ 2645

Query: 610  EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
                PV        +FL+ L DL   +   + +  +VS +P   V+W  +G ++  S+ +
Sbjct: 2646 ----PV--------VFLKALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKY 2692

Query: 670  HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 729
             F        L + +V PED G YTC      G   T+A + V + H G       + ++
Sbjct: 2693 DFLHTAGTRGLVVHDVSPEDAGLYTCH----VGSEETRARVRVHDLHVG----ITKRLKT 2744

Query: 730  VTASLGQSVLISCAI----AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 785
            +    G+S    C +    A DP     W   GK +   +  F+  +    + LV+++  
Sbjct: 2745 MEVLEGESCSFECVLSHESASDP---AMWTVGGKTV-GSSSRFQATRQGRKYILVVREAA 2800

Query: 786  PWHAGQYEILLKNRVGECS 804
            P  AG+    ++    + S
Sbjct: 2801 PSDAGEVVFSVRGLTSKAS 2819



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 67/245 (27%), Positives = 112/245 (45%), Gaps = 10/245 (4%)

Query: 19   VDPSRVDSMPLTEA-PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
            V P  + S+  ++A P F+   +N  +++G    F+  V G P P V W ++G+ +    
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170

Query: 78   RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
             ++++   +G   L+I AV   D G Y C A N  G      EL V+ + +        +
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLT-STDYDTAADA 5229

Query: 138  KTLGDRFSAPA-VETRPSIWGECP------PKFATKLGRVVVKEG-QMGRFSCKITGRPQ 189
                  FSA   + +R     E        P+   +L  + V  G ++ +F  K+ G P 
Sbjct: 5230 TESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPA 5289

Query: 190  PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
            P++ W K   PL  SA + +++K  +  LEI  V ++D G Y   + N  G A  SA L 
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349

Query: 250  IQGLD 254
            ++G D
Sbjct: 5350 VRGPD 5354



 Score = 91.7 bits (226), Expect = 6e-18
 Identities = 59/214 (27%), Positives = 91/214 (42%), Gaps = 15/214 (7%)

Query: 617 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 676
           P    AP FL       V  G   T++ Q+ GNP P+V W  +   +     F   Q G 
Sbjct: 4   PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD 63

Query: 677 QHSLCIQEVFPEDTGTYTCEAWNSAGE--------VRTQAVLTVQEPHDGTQPWFISKPR 728
            + L I ++   D+G Y C A N+ GE        V  +A    Q PH      F+ +P 
Sbjct: 64  LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH------FLLRPT 117

Query: 729 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPW 787
           S+    G      C + G P P V W +DG+ L +  G    V +  +   L ++  +P 
Sbjct: 118 SIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR 177

Query: 788 HAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 821
             G YE+  +N +G  S   +L++ + +A    R
Sbjct: 178 DGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 103/412 (25%), Positives = 150/412 (36%), Gaps = 37/412 (8%)

Query: 118  TVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPS---IWGECPPKFATKLGRVVVKE 174
            T+ + VE    +Q G   V   +     AP V   P    +  +  P F T+L    V++
Sbjct: 5081 TLGIGVEIKLVEQ-GPRRVEMCISKETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQD 5139

Query: 175  GQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTC 233
            G    F C +TG+P P V W K    L+      ++E + G   L I  V   D+GVY C
Sbjct: 5140 GYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRC 5199

Query: 234  LVVNGSGKASMSAELSIQ--------GLDSANRSFVRETKATNSDVRKEVTNVISKESKL 285
            L  N  G +S  AEL +           D+   S     +   S   +E T   + E +L
Sbjct: 5200 LAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSREQEGTESTTDEGQL 5259

Query: 286  DSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDS-PRTAPQTPVLQKTSSS 344
              +    +    +   R           P P    +L   KD  P TA     +      
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAP----RLYWFKDGQPLTASAHIRMTDKKIL 5315

Query: 345  ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP 404
             TL+   V  E        +S +       A    A    R P    +   S    + +P
Sbjct: 5316 HTLEIISVTREDSGQYAAYISNA-----MGAAYSSARLLVRGPDEPEEKPASDVHEQLVP 5370

Query: 405  MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTP-----VRRQEG 459
                     P+   +   ++VK+  ++ F  +V G P P V W  E        +     
Sbjct: 5371 ---------PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTP 5421

Query: 460  SIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVME 511
               V   A  H L LL    +  GTY+C ASNA GQ  CS +L V  L  +E
Sbjct: 5422 GYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 67/233 (28%), Positives = 102/233 (43%), Gaps = 31/233 (13%)

Query: 31   EAPAFILPPRNLCIKEGAT-AKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRGT 88
            + P  +   R+L +  G   AKF+ +V+GYP P++ W ++GQP+T+     + D  I  T
Sbjct: 5258 QLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHT 5317

Query: 89   FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
              ++  +V  ED G+Y    +N  GA   +  L V G    +                PA
Sbjct: 5318 LEII--SVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE--------------EKPA 5361

Query: 149  VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV--------P 200
             +    +    PP+   +     VK+G    FS K+ GRP P V WL+           P
Sbjct: 5362 SDVHEQL---VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418

Query: 201  LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
              P   V+ S +    VL    V +   G YTC+  N +G+A  SA L + GL
Sbjct: 5419 DTPGYTVASSAQQHSLVL--LDVGRQHQGTYTCIASNAAGQALCSASLHVSGL 5469



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 163/756 (21%), Positives = 268/756 (35%), Gaps = 126/756 (16%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
            G  A+FE          V W+++G  +   G   L   +     LV   V  +D G Y+C
Sbjct: 812  GGPAQFECET-SEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870

Query: 107  EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166
                 S              F  ++ +P V       F+   +  R              
Sbjct: 871  RVGEDSV------------DFRLRVSEPKVV------FAKEQLARR-------------- 898

Query: 167  LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
              ++  + G     SC++  + Q +VTW K    L  S++V +      + L +    Q 
Sbjct: 899  --KLQAEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQA 955

Query: 227  DVGVYTCLVVNGSGKASMSAELSIQ------GLDSANRSFVRETKATNSDVRKEVTNVIS 280
            D G Y+C     +G   +S  L ++        D    S V+     ++ +  EV    +
Sbjct: 956  DAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT 1011

Query: 281  -----KESKL--DSLEAAAKSKNCSS----PQRGGSPPWAANSQPQPPRES-KLESCKDS 328
                 K+ K    SL+   ++K C       Q G +     + + +  R S +L   +  
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPK 1071

Query: 329  PRTAPQTPVLQKT------SSSITLQAARVQPEPR--APGLGVLSPSGEERKRPAPPRPA 380
               A +  V  +       S+ ++ + A+ Q E      G  + S S    +     R  
Sbjct: 1072 MMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRL 1131

Query: 381  TFPTRQPGLGSQDVVS-KAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
              P  Q G       S +A  +R+       +    F K +S     + +   T    CE
Sbjct: 1132 VLP--QAGKADAGEYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCE 1189

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
            V+  P+ EV W+ +G  +      + +     +  L + +    D+G YSC A   +   
Sbjct: 1190 VAQ-PQTEVTWYKDGKKLS-SSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSF 1247

Query: 497  SCSWTLQVERLAVMEVAPSFSS---VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 553
                     +L + E    F+    V  +     G    L C V       +TW  +G+ 
Sbjct: 1248 ---------QLHITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKK 1297

Query: 554  IQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 610
            +  +   R      + +L +Q A   D G YTC A                     ++  
Sbjct: 1298 LSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEA-------------------GGQRLS 1338

Query: 611  YLLPVAPSKPTAPIFLQGLSDLKVMD--GSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668
            + L V  S+P A    + L+  KV    G+  T++ +V+     EV W  +G ++  S  
Sbjct: 1339 FHLDV--SEPKAVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSK 1395

Query: 669  FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFIS 725
               E  G    L +Q+    DTG Y+CE    AG  R    L V EP       QP    
Sbjct: 1396 VRMEAVGCTRRLVVQQACQADTGEYSCE----AGGQRLSFSLDVAEPKVVFAKEQP---- 1447

Query: 726  KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              R V A  G S  +SC +A      V W +DGK L
Sbjct: 1448 VHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKKL 1482



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 32/239 (13%)

Query: 24  VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
           +D    + AP F+  P+   +  G  A    ++ G P PQV+W ++ QP+ +G RF L  
Sbjct: 1   MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL-A 59

Query: 84  GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
                + L I  +   D G+Y C A N  G     V L V+   A               
Sbjct: 60  QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA--------------- 104

Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202
                         E  P F  +   + V+EG    F C++ G P+P V+W K    L +
Sbjct: 105 ------------CAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGE 152

Query: 203 PSA-RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI--QGLDSANR 258
           P   RV V E      L I      D G Y     N  G AS +A L +     D+A+R
Sbjct: 153 PDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 166/799 (20%), Positives = 279/799 (34%), Gaps = 143/799 (17%)

Query: 42   LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE--E 99
            +C KE  +A     VR  P   +   RN +  T G    L C +     +     HE   
Sbjct: 3697 MCGKERTSAMLT--VRAMPSKFIEGLRN-EEATEGDTATLWCELSKAAPVEWRKGHETLR 3753

Query: 100  DRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
            D  +++          Q+     V+ G ++   GQ   S TL  R               
Sbjct: 3754 DGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVR--------------A 3799

Query: 159  CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
             P +F   +     +EG      C+++      V W KG+  L+   R S+ +      L
Sbjct: 3800 LPARFIEDVKNQEAREGATAVLQCELS--KAAPVEWRKGSETLRGGDRYSLRQDGTRCEL 3857

Query: 219  EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV 278
            +IHG++  D G Y+C+     G+   SA L++              +A     R+ + ++
Sbjct: 3858 QIHGLSVADTGEYSCV----CGQERTSATLTV--------------RAPQPVFREPLQSL 3899

Query: 279  ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESC----------KDS 328
             ++E    +L+        +     G     AN +    RE +L+ C          ++ 
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGR----REPRLQGCTAELVLQDLQRED 3955

Query: 329  PRTAPQTPVLQKTSSSITLQAARV------QPEPRAPG--------LGVLSPSGEERKRP 374
                  T   Q TS+++T+ AA V      Q +    G        L     S E RK  
Sbjct: 3956 TGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGS 4015

Query: 375  APPRP-ATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAF-----------------PKF 416
                P A +   Q G  ++ +V     R +  E   D                    PKF
Sbjct: 4016 LQLFPCAKYQMVQDGAAAELLV-----RGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKF 4070

Query: 417  ESKPQSQEVKENQTVKFRCEVSGIPKPEVA-WFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
            +++ QS E +     +  C++S      V  W  EG  +       E+     +  L + 
Sbjct: 4071 KTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGP-KYEMRSQGATRELLIH 4129

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
            +   +D+G Y+C     +   S         L V E   +    L D  V   +D    C
Sbjct: 4130 QLEAKDTGEYACVTGGQKTAAS---------LRVTEPEVTIVRGLVDAEVTADEDVEFSC 4180

Query: 536  SVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-----LHIQDALPEDHGTYTCLAENALG 590
             V       + W L G P+Q +    E  V +     L ++   PED GT +      LG
Sbjct: 4181 EVSRAGATGVQWCLQGLPLQ-SNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSF----HLG 4235

Query: 591  QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNP 650
              + SA +TV   + +                   L+ L D+++ +G   +   ++S   
Sbjct: 4236 NHASSAQLTVRAPEVT------------------ILEPLQDVQLSEGQDASFQCRLSRAS 4277

Query: 651  PPEVIWLHNGNEIQESE--DFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 708
              E  W   G  +Q +E  D   EQ GT H L + +V  ED GT +      + E + + 
Sbjct: 4278 GQEARWALGGVPLQANEMNDITVEQ-GTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKV 4336

Query: 709  VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGH 767
                       +   +    +V A  G   L  C ++        WL D + +   +   
Sbjct: 4337 T---------AKNTVVRGLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAE 4387

Query: 768  FEVLQNEDVFTLVLKKVQP 786
                +N     L+LK ++P
Sbjct: 4388 VVFFENGLRHLLLLKNLRP 4406



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 9/199 (4%)

Query: 623  PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 681
            P F + L+D     G  V +  +V+G P P + W  +G  +Q +      E      +L 
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 682  IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 741
            +  +   D+G Y C A ++AG   T   + VQ P     P F++K R+     G+    +
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128

Query: 742  CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ--NEDVFTLVLKKVQPWHAGQYEILLKNR 799
            C I G P+P + W +DG AL      F+ L      +  LV++       G YE  L NR
Sbjct: 6129 CTIEGAPYPQIRWYKDG-ALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187

Query: 800  VGECSCQVSLMLQNSSARA 818
            +G       L +Q+   +A
Sbjct: 6188 LGSARASAELRIQSPMLQA 6206



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 156/687 (22%), Positives = 265/687 (38%), Gaps = 117/687 (17%)

Query: 61   EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
            + +V W+++G+ ++   +  ++  +  T  LV+    +   G+Y+CEA    G+++++  
Sbjct: 1470 QTEVMWYKDGKKLSFSSKVRMEA-VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFH 1524

Query: 121  LTV---EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQM 177
            L V   +  FAK+  QP   +                               V  + G  
Sbjct: 1525 LHVAEPKAVFAKE--QPASRE-------------------------------VQAEAGTS 1551

Query: 178  GRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
               SC++  + Q +VTW K    L  S++V +      + L +    Q D G Y+C    
Sbjct: 1552 ATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA-- 1608

Query: 238  GSGKASMSAELSIQGL-----DSANRSFVRETKAT---NSDVRKEVTNV--------ISK 281
            G  + S    ++   +       A+R    E  A+   + +V +  T V        +S 
Sbjct: 1609 GDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668

Query: 282  ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES------KLESCKDSPRTAPQT 335
             SK+  +EA   ++     Q G +     + +    R S      +LE  + S R   + 
Sbjct: 1669 SSKV-RVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEP-QISERPCRRE 1726

Query: 336  PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGL-GSQDV 394
            P++ K    I L A    P   A  +  L    E R+       +   T    + G+Q +
Sbjct: 1727 PLVVKEHEDIILTATLATPS--AATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVL 1784

Query: 395  VSKAANRRIPMEGQR-----DSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFL 449
             S   + R+  EGQ      +    KF    +    +   TV   CE+S     EV W  
Sbjct: 1785 DSAIYSCRVGAEGQDFPVQVEEVAAKFCRLLEPVCGELGGTVTLACELSPACA-EVVWRC 1843

Query: 450  EGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAV 509
              T +R  +   ++  +     L +L  R  D+G Y C + +     S   T+ V R+  
Sbjct: 1844 GNTQLRVGK-RFQMVAEGPVRSLTVLGLRAEDAGEYVCESRD--DHTSAQLTVSVPRVV- 1899

Query: 510  MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAE 567
                  F S L      EG +   QC V  + V  + W  +G  +Q +   +  ++G + 
Sbjct: 1900 -----KFMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASH 1953

Query: 568  -LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 626
             L I D + ED G  T  AE A    S SA + V E           PV        +F 
Sbjct: 1954 SLTISDLVLEDAGQITVEAEGA----SSSAALRVREA----------PV--------LFK 1991

Query: 627  QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 686
            + L    V + S VT+ V+++  P PE+ W  N   +   ++      G +H L +  V 
Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050

Query: 687  PEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
              D G + CE      + +TQA LTV+
Sbjct: 2051 FADRGFFGCE----TPDDKTQAKLTVE 2073



 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 13/250 (5%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS--QEGSLCS 1154
            AP F  +LQ+  V +G  +   C V+  P  ++ W  +GK L+     +++  Q+G    
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG-HQ 5183

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            + I   +P D G+Y+C+A+N  G +    ++ VD      +T A   +S    S+   + 
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243

Query: 1215 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTGTQPITCTWMK 1273
              E + T       ++       PQ+++   D +V  G  +  F  KV G       W K
Sbjct: 5244 SREQEGT-------ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296

Query: 1274 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1333
              + +  S H+++ + +    L I++  +E  G Y   + N +G+  +   L +V  PD 
Sbjct: 5297 DGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPDE 5355

Query: 1334 PAGTPCASDI 1343
            P   P ASD+
Sbjct: 5356 PEEKP-ASDV 5364



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 153/756 (20%), Positives = 264/756 (34%), Gaps = 107/756 (14%)

Query: 37   LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
            L  R L  + GA+A     V    + +VTW+++G+ ++S  +  ++     T  LV+   
Sbjct: 895  LARRKLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEA-TGCTRRLVVQQA 952

Query: 97   HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
             + D G+Y+CEA    G ++++  L V+        +P V                    
Sbjct: 953  GQADAGEYSCEA----GGQRLSFHLDVK--------EPKVVFA----------------- 983

Query: 157  GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
                 K       V  + G     SC++  + Q +V W K    L  S +V V  K   +
Sbjct: 984  -----KDQVAHSEVQAEAGASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRR 1037

Query: 217  VLEIHGVNQDDVGVYTCLVVN---------GSGKASMSAELSIQGLDSANRSFVRETKAT 267
             L +    + D G Y+C                K   + E S+     A           
Sbjct: 1038 RLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCE 1097

Query: 268  NSDVRKEVT-----NVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-K 321
             +  + EVT       +S  SK+  +E    ++    PQ G +     + +    R S  
Sbjct: 1098 VAQAQTEVTWYKDGKKLSSSSKV-GMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSFH 1156

Query: 322  LESCKDSPRTAPQTPVLQK------TSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA 375
            L   +     A +  V  +      T++ ++ + A+ Q E      G    S  + +   
Sbjct: 1157 LHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEV 1216

Query: 376  PPRPATFPTRQPGLGSQDVVS-KAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTV 431
                     +Q G       S +A  +R+  +    +  + F K +        +   + 
Sbjct: 1217 KGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRTEAGASA 1276

Query: 432  KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
               CEV+   + EV W+ +G  +      + +        L + +A   D+G Y+C A  
Sbjct: 1277 TLSCEVAQ-AQTEVTWYKDGKKL-SSSSKVRIEAAGCMRQLVVQQAGQADAGEYTCEAGG 1334

Query: 492  AQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 551
               +LS    +   +    +   +   V  +   I      L C V       +TW  +G
Sbjct: 1335 Q--RLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIA----TLSCEVAQAQT-EVTWYKDG 1387

Query: 552  QPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 608
            + +  +   R         L +Q A   D G Y+C A                     ++
Sbjct: 1388 KKLSSSSKVRMEAVGCTRRLVVQQACQADTGEYSCEA-------------------GGQR 1428

Query: 609  SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 668
              + L VA  K           +++   G+  T++ +V+     EV+W  +G ++  S  
Sbjct: 1429 LSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKKLSFSSK 1487

Query: 669  FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFIS 725
               E  G    L +Q+      G Y+CE    AG  R    L V EP       QP    
Sbjct: 1488 VRMEAVGCTRRLVVQQAGQAVAGEYSCE----AGSQRLSFHLHVAEPKAVFAKEQP---- 1539

Query: 726  KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
              R V A  G S  +SC +A      V W +DGK L
Sbjct: 1540 ASREVQAEAGTSATLSCEVA-QAQTEVTWYKDGKKL 1574



 Score = 78.2 bits (191), Expect = 7e-14
 Identities = 172/822 (20%), Positives = 308/822 (37%), Gaps = 150/822 (18%)

Query: 60   PEPQ-VTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQV 117
            P P+ V W+++  P++   +F +   + G  + L I  +   D G Y C+A +   + +V
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMS--LEGQMAELRILRLMPADAGVYRCQAGSAHSSTEV 2551

Query: 118  TVE---LTVEG-------------SFAKQL------------GQPVVSKTLGD------- 142
            TVE   +TV G             SF+ +L            G P+ + +  +       
Sbjct: 2552 TVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611

Query: 143  ----------------RFSAPAVETRPSIWGECPPK-FATKLGRVVVKEGQMGRFSCKIT 185
                            R S+  V T   +     P  F   L  +  +E       C+++
Sbjct: 2612 HTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS 2671

Query: 186  GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245
              P+  V W K  V L PS +       G + L +H V+ +D G+YTC V    G     
Sbjct: 2672 D-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHV----GSEETR 2726

Query: 246  AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-- 303
            A + +  L              +  + K +  +   E +  S E     ++ S P     
Sbjct: 2727 ARVRVHDL--------------HVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTV 2772

Query: 304  GSPPWAANSQPQPPRESK---LESCKDSPRTAPQTPV----LQKTSSSITLQ--AARVQP 354
            G     ++S+ Q  R+ +   L   + +P  A +       L   +S I  +  AA ++P
Sbjct: 2773 GGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKP 2832

Query: 355  ---EPRAPGLGV-----LSPSGEE----RKRPAPPRPATFPTRQPGLGSQDVVSKAANR- 401
               +  APG  V     LS +G      + R A  +   +     G  +  V+  A+ + 
Sbjct: 2833 LEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKD 2892

Query: 402  ----RIPMEGQRDSAFPKFESKPQ-------SQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
                   +E  + +A    E K         + +V+E  T  F C+    P   V W  +
Sbjct: 2893 AGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEH-PAATVTW-RK 2950

Query: 451  GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
            G    R  G  +  ++  +  L +      DS TY+C    AQ +      +Q  R+ ++
Sbjct: 2951 GLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQAQSRAQL--LVQGRRVHII 3008

Query: 511  EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 570
            E        L+D  V EG     +C +       + W L+  P+            EL+ 
Sbjct: 3009 ED-------LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLH---------ANELNE 3052

Query: 571  QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 630
             DA P   G Y  L    L Q++     T++ +   +++   L V   KP+  +F + L+
Sbjct: 3053 IDAQP---GGYHVL---TLRQLALKDSGTIYFEAGDQRASAALRVT-EKPS--VFSRELT 3103

Query: 631  DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 690
            D  + +G  +T+  + S    P V W  +G  ++ S        G +  L I     +D+
Sbjct: 3104 DATITEGEDLTLVCETSTCDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDS 3162

Query: 691  GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 750
            G Y CE    AG   + +++ V          F    + +    G +  + C ++    P
Sbjct: 3163 GRYKCE----AGGACSSSIVRVH----ARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP 3214

Query: 751  TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 792
             V W   G  + +    + + Q   +  LV++ ++P  +G+Y
Sbjct: 3215 -VKWCY-GNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 65/234 (27%), Positives = 97/234 (41%), Gaps = 43/234 (18%)

Query: 23  RVDSMPLTEAPAFILPP----RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
           R ++M    APA   PP    R   + EG  A+    V G P+P+  W ++GQ +T G R
Sbjct: 226 RREAMRAEGAPAS--PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283

Query: 79  FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
            ++    +  F L I    + DRG YTC A+N  G    +V + V               
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR-------------- 329

Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
                   PAV             F  +L  + V+E +   F C++  +P  +  W K  
Sbjct: 330 -------EPAVP------------FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEE 369

Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252
             L  SA+  + E+   + L +  V+ DD  VY C    GS      AEL++QG
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTV---AELAVQG 420



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 156/751 (20%), Positives = 273/751 (36%), Gaps = 117/751 (15%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYT 105
            GA+A     V    + +V W+++G+ ++S  +  ++  G R    LV+    + D G Y+
Sbjct: 997  GASATLSCEV-AQAQTEVMWYKDGKKLSSSLKVHVEAKGCRRR--LVVQQAGKTDAGDYS 1053

Query: 106  CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFAT 165
            CEA                                G R S     T P +      K  +
Sbjct: 1054 CEAR-------------------------------GQRVSFRLHITEPKMMFA---KEQS 1079

Query: 166  KLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQ 225
                V  + G     SC++  + Q +VTW K    L  S++V +  K   + L +    +
Sbjct: 1080 VHNEVQAEAGASAMLSCEVA-QAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGK 1138

Query: 226  DDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRETKAT-------NSDVRKEV 275
             D G Y+C     +G   +S  L I   +G+ +  +S   E +A        + +V +  
Sbjct: 1139 ADAGEYSC----EAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQ 1194

Query: 276  TNV--------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCK 326
            T V        +S  SK+  +E    ++     Q G +     + +    R S +L   +
Sbjct: 1195 TEVTWYKDGKKLSSSSKV-RMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITE 1253

Query: 327  DSPRTAPQTPVLQKT------SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA 380
                 A +  V  +       S++++ + A+ Q E      G    S  + +  A     
Sbjct: 1254 PKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMR 1313

Query: 381  TFPTRQPGLGSQ-DVVSKAANRRIPME---GQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
                +Q G     +   +A  +R+       +  + F K +   +  + +        CE
Sbjct: 1314 QLVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCE 1373

Query: 437  VSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQL 496
            V+   + EV W+ +G  +      + +     +  L + +A   D+G YSC A   +  L
Sbjct: 1374 VAQA-QTEVTWYKDGKKLS-SSSKVRMEAVGCTRRLVVQQACQADTGEYSCEAGGQR--L 1429

Query: 497  SCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY 556
            S S  +   ++   +  P    V ++     G    L C V       + W  +G+ + +
Sbjct: 1430 SFSLDVAEPKVVFAKEQP----VHREVQAQAGASTTLSCEVAQAQT-EVMWYKDGKKLSF 1484

Query: 557  ARSTCEAGVA---ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 613
            +       V     L +Q A     G Y+C A                    S++  + L
Sbjct: 1485 SSKVRMEAVGCTRRLVVQQAGQAVAGEYSCEA-------------------GSQRLSFHL 1525

Query: 614  PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 673
             VA  K           +++   G+  T++ +V+     EV W  +G ++  S     E 
Sbjct: 1526 HVAEPKAVFAKEQPASREVQAEAGTSATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEA 1584

Query: 674  RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSV 730
             G    L +QE    D G Y+C+    AG+ R    L V EP       QP      R V
Sbjct: 1585 VGCTRRLVVQEAGQADAGEYSCK----AGDQRLSFHLHVAEPKVVFAKEQP----AHREV 1636

Query: 731  TASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
             A  G S  +SC +A      V W +DGK L
Sbjct: 1637 QAEAGASATLSCEVA-QAQTEVTWYKDGKKL 1666



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 161/754 (21%), Positives = 264/754 (35%), Gaps = 184/754 (24%)

Query: 33   PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG-TFSL 91
            P F  P ++L  +EG+TA  +  +   P   V W + G  + + GR   +  ++G T  L
Sbjct: 3890 PVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGR--REPRLQGCTAEL 3946

Query: 92   VIHAVHEEDRGKYTCEATNGSGARQVTVELTV---------------------------- 123
            V+  +  ED G+YTC  T GS A   T+ +T                             
Sbjct: 3947 VLQDLQREDTGEYTC--TCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSR 4004

Query: 124  ------------------------EGSFAKQLGQPVVSKTLGD-RFSAPAVETRPSIWGE 158
                                    +G+ A+ L + V  +  GD        ++  S+   
Sbjct: 4005 AGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVR 4064

Query: 159  CP-PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT-WLKGNVPLQPSARVSVSEKNGMQ 216
             P PKF T+L  +  + G + R  C+++      V  WLK  V L    +  +  +   +
Sbjct: 4065 VPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATR 4124

Query: 217  VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVT 276
             L IH +   D G Y C  V G  K + S               +R T+   + VR  V 
Sbjct: 4125 ELLIHQLEAKDTGEYAC--VTGGQKTAAS---------------LRVTEPEVTIVRGLVD 4167

Query: 277  NVISKESKLDSLEAAAKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKD----SPRT 331
              ++ +  ++         +C   + G +   W     P    E    + +D    + R 
Sbjct: 4168 AEVTADEDVEF--------SCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRIHTLRL 4219

Query: 332  APQTPVLQKT-SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG 390
               TP    T S  +   A+  Q   RAP + +L P                        
Sbjct: 4220 KGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEP------------------------ 4255

Query: 391  SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLE 450
             QDV           EGQ D++F    S+   QE         R  + G+P         
Sbjct: 4256 LQDVQLS--------EGQ-DASFQCRLSRASGQEA--------RWALGGVP--------- 4289

Query: 451  GTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVM 510
               ++  E +    E    H L L K    D+GT S          +CS   Q++  A  
Sbjct: 4290 ---LQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVG------TCSSEAQLKVTAKN 4340

Query: 511  EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST----CEAGVA 566
             V       L++   +EG + + +C +    V   TWLL+ +P+  + +      E G+ 
Sbjct: 4341 TVVRG----LENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLR 4396

Query: 567  E-LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 625
              L +++  P+D    T LA    G +  SA++TV   +                     
Sbjct: 4397 HLLLLKNLRPQDSCRVTFLA----GDMVTSAFLTVRGWRLE------------------I 4434

Query: 626  LQGLSDLKVMDGSQVTMTVQVS-GNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLCIQ 683
            L+ L +  V  G+Q   T  +S   P  E  W  NG  +Q +  D+     G+ H+L ++
Sbjct: 4435 LEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLR 4494

Query: 684  EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 717
               P   G  T    ++    R   +     P D
Sbjct: 4495 SAQPHHAGEVTFACRDAVASARLTVLGLPDPPED 4528



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 107/500 (21%), Positives = 181/500 (36%), Gaps = 101/500 (20%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR-VSVSEKNGMQVL 218
            PP F  +L     + G+  + +C++TG P+P ++W K    +Q     + + + +G   L
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 219  EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT----NSDVRKE 274
             +  +   D G Y C   + +G  S   ++ +Q        FV + +A+      D +  
Sbjct: 6073 ILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ----VPPRFVNKVRASPFVEGEDAQFT 6128

Query: 275  VT---------------NVISKESKLDSLE------------AAAKSK----NCSSPQRG 303
             T                +++  +K  +L             AA+K       C    R 
Sbjct: 6129 CTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRL 6188

Query: 304  GSPPWAANSQPQPPRESKLESC-KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLG 362
            GS   +A  + Q P     E C ++    A +   L++    +T    R+   P+APG  
Sbjct: 6189 GSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERADQEVTSVLKRLLG-PKAPG-- 6245

Query: 363  VLSPSGEERKRPAP-PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
               PS  +   P P PR A  P  Q       V   +    +P    +       E +P+
Sbjct: 6246 ---PSTGDLTGPGPCPRGA--PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPE 6300

Query: 422  SQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRD 481
            +    +  TV  R E +  P                 G+ E+  D  SH   +++  T+ 
Sbjct: 6301 AIARAQEWTVPIRMEGAAWPGA---------------GTGELLWDVHSH---VVRETTQR 6342

Query: 482  SGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 541
            + TY    ++                      PS    ++D     G     +  + G P
Sbjct: 6343 TYTYQAIDTHTARP------------------PSMQVTIEDVQAQTGGTAQFEAIIEGDP 6384

Query: 542  VPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 596
             P +TW  +   +Q   ST      E     L ++    +D G YTCLA+N  GQV C A
Sbjct: 6385 QPSVTWYKDS--VQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKA 6442

Query: 597  WVTV--------HEKKSSRK 608
             + V         EK+S R+
Sbjct: 6443 ELLVLGGDNEPDSEKQSHRR 6462



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 36/92 (39%), Positives = 51/92 (55%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F   +++ EV +G    FDC + G P P V WFKD + + E  H+ I+ D+ G   LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I+ V   D   Y C A NS+G ++  AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)

Query: 1751 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1810
            E K    P FS T  D E   G A R +C +    D    W KD   + + RH  ID   
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950

Query: 1811 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1862
            DG CSL+I+ +   D   YTC+  N  G+ T +A ++V   E+  E    GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 138/635 (21%), Positives = 245/635 (38%), Gaps = 100/635 (15%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            P +F  KL      EG      C+++      V W KG+  L+   R  + +   M  L+
Sbjct: 3273 PAQFIGKLRNKEATEGATATLRCELS--KAAPVEWRKGSETLRDGDRYCLRQDGAMCELQ 3330

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
            I G+   D   Y+C+     G+   SA L+I+ + +    F+   +   S +      + 
Sbjct: 3331 IRGLAMVDAAEYSCV----CGEERTSASLTIRPMPA---HFIGRLRHQES-IEGATATLR 3382

Query: 280  SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVL- 338
             + SK   +E     ++     R        +S  Q     +L+ C  +   A +   + 
Sbjct: 3383 CELSKAAPVEWRKGRESLRDGDR--------HSLRQDGAVCELQICGLAVADAGEYSCVC 3434

Query: 339  --QKTSSSITLQA------ARVQPEPRAPG--------LGVLSPSGEERKRPAPPRPA-T 381
              ++TS+++T++A        ++ E    G        L  ++P  E RK P   R    
Sbjct: 3435 GEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPV-EWRKGPENLRDGDR 3493

Query: 382  FPTRQPGLGSQ----DVVSKAANRRIPMEGQ-RDSAFPKFESKPQS--QEVKENQ----- 429
            +  RQ G   +     +    A   + + GQ R SA     + P    ++VK  +     
Sbjct: 3494 YILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPARFIEDVKNQEAREGA 3553

Query: 430  TVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTA 489
            T   +CE++     E   + +G+   R      + +D     L +      D+G YSC  
Sbjct: 3554 TAVLQCELNSAAPVE---WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVC 3610

Query: 490  SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
                GQ   S  L V  L +      F+  L++    EG   VL+C +  + +  + W  
Sbjct: 3611 ----GQERTSAMLTVRALPI-----KFTEGLRNEEATEGATAVLRCEL--SKMAPVEWWK 3659

Query: 550  NGQPIQYA--RSTCEAGV-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 606
              + ++     S  + G   EL I+  + ED G Y C+     G+   SA +TV      
Sbjct: 3660 GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMC----GKERTSAMLTVR----- 3710

Query: 607  RKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQES 666
                      PSK     F++GL + +  +G   T+  ++S   P E  W      +++ 
Sbjct: 3711 --------AMPSK-----FIEGLRNEEATEGDTATLWCELSKAAPVE--WRKGHETLRDG 3755

Query: 667  EDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 726
            +     Q G++  L I+ +   D G Y+C      G+ RT A LTV+         FI  
Sbjct: 3756 DRHSLRQDGSRCELQIRGLAVVDAGEYSC----VCGQERTSATLTVR----ALPARFIED 3807

Query: 727  PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 761
             ++  A  G + ++ C ++      V W +  + L
Sbjct: 3808 VKNQEAREGATAVLQCELS--KAAPVEWRKGSETL 3840



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 60/243 (24%), Positives = 96/243 (39%), Gaps = 22/243 (9%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1154
            AP F  +   + V EG +   +C+V   P   + W+ +G+ L       + + + G   +
Sbjct: 109  APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168

Query: 1155 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1214
            + I  A P D G Y+  A+N  G A  +  + VD   A          + RP +S   +L
Sbjct: 169  LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD--------TASRPGTSTAALL 220

Query: 1215 G--TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1272
                     ++ + AP +PP                V  G+   L   VTG       W 
Sbjct: 221  AHLQRRREAMRAEGAPASPPSTG--------TRTCTVTEGKHARLSCYVTGEPKPETVWK 272

Query: 1273 KFRKQIQES-EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1331
            K  + + E   H+  E+++    L IL  +Q   G YT    N +G   + V L VV +P
Sbjct: 273  KDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREP 331

Query: 1332 DPP 1334
              P
Sbjct: 332  AVP 334



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 62/229 (27%), Positives = 82/229 (35%), Gaps = 25/229 (10%)

Query: 432  KFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASN 491
            KF+ +V G P P + WF +G P+      I + +    H L ++     DSG Y+   SN
Sbjct: 5279 KFQLKVKGYPAPRLYWFKDGQPL-TASAHIRMTDKKILHTLEIISVTREDSGQYAAYISN 5337

Query: 492  AQGQLSCSWTLQVERLAVME-----------VAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
            A G    S  L V      E           V P          V +G        V G 
Sbjct: 5338 AMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGR 5397

Query: 541  PVPRITWLLN---------GQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQ 591
            PVP + WL           G           A    L + D   +  GTYTC+A NA GQ
Sbjct: 5398 PVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQ 5457

Query: 592  VSCSAWVTV----HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 636
              CSA + V      ++  +  E L+       T  I  QGL      D
Sbjct: 5458 ALCSASLHVSGLPKVEEQEKVKEALISTFLQGTTQAISAQGLETASFAD 5506



 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 13/151 (8%)

Query: 114  ARQVTVELTVEGSFAKQLG---------QPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
            A++ TV + +EG+     G           VV +T    ++  A++T  +     PP   
Sbjct: 6305 AQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTAR----PPSMQ 6360

Query: 165  TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
              +  V  + G   +F   I G PQP VTW K +V L  S R+S  ++     L +  V 
Sbjct: 6361 VTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVA 6420

Query: 225  QDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
              D GVYTCL  N  G+    AEL + G D+
Sbjct: 6421 SKDAGVYTCLAQNTGGQVLCKAELLVLGGDN 6451



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P    TI D++   G  A+F+  IEG P P V W+KD   + +S        E    SL+
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLV 6415

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
            +  V   D   YTC A N+ G+  C AEL+V     G+ E + E++
Sbjct: 6416 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV---LGGDNEPDSEKQ 6458



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 25/92 (27%), Positives = 49/92 (53%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F + + D     G   +  C++ G P P + W+KD ++++   H  +  D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +  + G D  +Y C A ++ G  +   +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)

Query: 1756 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 1814
            V P F   +R    VEG  A+F C IEG P P++ W+KD   +     FQ +     G  
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165

Query: 1815 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1850
             L+I     +D   Y C+ VN LG A  +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 75/376 (19%), Positives = 137/376 (36%), Gaps = 38/376 (10%)

Query: 413  FPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYL 472
            F K +   +  + +   +    CEV+   + EV W+ +G  +      + +     +  L
Sbjct: 1442 FAKEQPVHREVQAQAGASTTLSCEVAQA-QTEVMWYKDGKKLSFSS-KVRMEAVGCTRRL 1499

Query: 473  CLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFV 532
             + +A    +G YSC A + +  LS    +   +    +  P+   V  +     G    
Sbjct: 1500 VVQQAGQAVAGEYSCEAGSQR--LSFHLHVAEPKAVFAKEQPASREVQAEA----GTSAT 1553

Query: 533  LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA---ELHIQDALPEDHGTYTCLAENAL 589
            L C V       +TW  +G+ +  +       V     L +Q+A   D G Y+C      
Sbjct: 1554 LSCEVAQAQT-EVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSC------ 1606

Query: 590  GQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGN 649
                         K   ++  + L VA  K           +++   G+  T++ +V+  
Sbjct: 1607 -------------KAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVA-Q 1652

Query: 650  PPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAV 709
               EV W  +G ++  S     E  G    L +Q+    D G Y+CEA       R    
Sbjct: 1653 AQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLH-- 1710

Query: 710  LTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 769
            +   EP    +P    +   +     + ++++  +A     TV WL+DG  + +   H E
Sbjct: 1711 VAELEPQISERP---CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRH-E 1766

Query: 770  VLQNEDVFTLVLKKVQ 785
                 D  TL +   Q
Sbjct: 1767 TASQGDTHTLTVHGAQ 1782



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 86/385 (22%), Positives = 152/385 (39%), Gaps = 62/385 (16%)

Query: 416  FESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLL 475
            F  + + QE  E  T   RCE+S     E   + +G    R      + +D     L + 
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAPVE---WRKGRESLRDGDRHSLRQDGAVCELQIC 3420

Query: 476  KARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQC 535
                 D+G YSC      G+   S TL V+ L        F+  L++   +EG   +L C
Sbjct: 3421 GLAVADAGEYSCVC----GEERTSATLTVKALPA-----KFTEGLRNEEAVEGATAMLWC 3471

Query: 536  SVRGTPVPRITW------LLNGQP--IQYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 587
             +  + V  + W      L +G    ++   + CE  +  L + DA     G Y C+   
Sbjct: 3472 EL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADA-----GEYLCVC-- 3522

Query: 588  ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 647
              GQ   SA +T+            LP          F++ + + +  +G+   +  +++
Sbjct: 3523 --GQERTSATLTIRA----------LPAR--------FIEDVKNQEAREGATAVLQCELN 3562

Query: 648  GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 707
               P E  W      +++ + +   Q GT+  L I+ +   DTG Y+C      G+ RT 
Sbjct: 3563 SAAPVE--WRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSC----VCGQERTS 3616

Query: 708  AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGH 767
            A+LTV+         F    R+  A+ G + ++ C ++      V W + G    +D   
Sbjct: 3617 AMLTVR----ALPIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWK-GHETLRDGDR 3669

Query: 768  FEVLQNEDVFTLVLKKVQPWHAGQY 792
              + Q+     L ++ +    AG+Y
Sbjct: 3670 HSLRQDGARCELQIRGLVAEDAGEY 3694



 Score = 61.2 bits (147), Expect = 9e-09
 Identities = 82/341 (24%), Positives = 117/341 (34%), Gaps = 35/341 (10%)

Query: 503  QVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR---- 558
            +V +    +  P FS    D     G    L+C V      R  WL +G  +   R    
Sbjct: 4887 KVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHI 4946

Query: 559  STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 618
                 G   L I      D G YTC   N  GQV+ SA V V   +S  +S     +  +
Sbjct: 4947 DQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDDA 5006

Query: 619  KPTAPIFLQGL----SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF---HF 671
               A   L  L    S  +V D        +    P     W       +E E F    F
Sbjct: 5007 FRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW----QTYREDEHFICIRF 5062

Query: 672  EQ--RGTQHSLCIQEVFPE----------DTGTYTCEAWNSAGEVRTQAVLTVQEP---- 715
            E      Q     QE+F            + G    E   S     T A +   EP    
Sbjct: 5063 EALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISK---ETPAPVVPPEPLPSL 5119

Query: 716  -HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNE 774
                  P F+++ ++     G  V   C + G P P+V W +DGK L +D  +      +
Sbjct: 5120 LTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQ 5179

Query: 775  DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 815
                L++  V P   G Y  L +N +G  S +  L +  +S
Sbjct: 5180 GGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTS 5220



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 56/262 (21%), Positives = 103/262 (39%), Gaps = 39/262 (14%)

Query: 1079 RGHAGTTDNE--KRSESQGTAPAFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNG 1135
            +G+  + + E  + +  +G  P   ++L+D+ VA G +L   Q +V   P   + W  +G
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298

Query: 1136 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1195
            + L  +  I ++ +  L ++ I     ED G Y     N  G A  S ++ V        
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV-------- 5350

Query: 1196 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1255
             + P+    +P S +   L                     +PP++++    +KV+ G S+
Sbjct: 5351 -RGPDEPEEKPASDVHEQL---------------------VPPRMLERFTPKKVKKGSSI 5388

Query: 1256 ELFGKVTGTQPITCTWMKFRKQI------QESEHMKVENSENGSKLTILAARQEHCGCYT 1309
                KV G    T  W++   +        ++    V +S     L +L   ++H G YT
Sbjct: 5389 TFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYT 5448

Query: 1310 LLVENKLGSRQAQVNLTVVDKP 1331
             +  N  G      +L V   P
Sbjct: 5449 CIASNAAGQALCSASLHVSGLP 5470



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 58/247 (23%), Positives = 88/247 (35%), Gaps = 42/247 (17%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            AP F  + +   V+ GK   L CQ+  +P   + W  + + +       L+Q+G L  ++
Sbjct: 9    APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            I      D G Y C A+N  G+A  +  + VD   A                        
Sbjct: 69   ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAAC----------------------- 105

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
                             A   P  +  P   +VR G       +V G+     +W K  +
Sbjct: 106  -----------------AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGR 148

Query: 1277 QIQESE--HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
            ++ E +   ++VE     S L I AAR    G Y +  EN LG+  A   L V       
Sbjct: 149  RLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADT 208

Query: 1335 AGTPCAS 1341
            A  P  S
Sbjct: 209  ASRPGTS 215



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 78/327 (23%), Positives = 132/327 (40%), Gaps = 49/327 (14%)

Query: 394  VVSKAANRRIPMEGQRDSAFPK-------FESKPQSQEVKENQTVKFRCEVSGIPKPEVA 446
            V+  A    +  EG   SA  +       F+ K + Q V+E  +V    E++  P PE+ 
Sbjct: 1961 VLEDAGQITVEAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTR-PWPELR 2019

Query: 447  WFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVER 506
            W    T +   + ++E++ +   H L L      D G + C   + + Q     T+++ +
Sbjct: 2020 WTRNATALAPGK-NVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQ--AKLTVEMRQ 2076

Query: 507  LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 566
            + ++    +  +  +  A +E Q  +    V G      +W  +G   Q    TC   V 
Sbjct: 2077 VRLVRGLQAVEAREQGTATMEVQ--LSHADVDG------SWTRDGLRFQQG-PTCHLAVR 2127

Query: 567  ----ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 622
                 L +    PED G     AE     V  SA + V E          LPV+ S+P  
Sbjct: 2128 GPMHTLTLSGLRPEDSGLMVFKAEG----VHTSARLVVTE----------LPVSFSRP-- 2171

Query: 623  PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 682
                  L D+   +  +VT+  ++S  P  +V WL +G E++  +      +G   SL I
Sbjct: 2172 ------LQDVVTTEKEKVTLECELS-RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTI 2224

Query: 683  QEVFPEDTGTYTCEAWN--SAGEVRTQ 707
                  D G Y C+A +  S+  V+ Q
Sbjct: 2225 YRCEFADQGVYVCDAHDAQSSASVKVQ 2251



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)

Query: 1758 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            P   + +RDL+V  G+  A+F  K++GYP P + WFKD Q +  S H ++  D+    +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
             I  V  +D  +Y     N++G A  +A L+V   +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 1/107 (0%)

Query: 712 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 771
           + +P     P F+++P++   S+G+   +SC I G+P P V W +D + +      F + 
Sbjct: 1   MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAG-ARFRLA 59

Query: 772 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818
           Q+ D++ L +  +    +GQY    +N +GE    V L +   +A A
Sbjct: 60  QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACA 106



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 1/89 (1%)

Query: 161  PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLE 219
            P F  +L    V  GQ    +C+++ +P  Q TW K   PL+ S+RV +S      Q+L 
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
            I  V  +D+GVYTC V N  G  + +  L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 9/150 (6%)

Query: 1699 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP 1758
            N + A    +++ + S  +   S  G+ T+ L A      E +        AE  P   P
Sbjct: 188  NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMR-------AEGAPASPP 240

Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
              S   R   V EG  AR  C + G P PE VW KD Q + E R   +  D   N  L I
Sbjct: 241  --STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
                  D   YTC A N +G+   +  ++V
Sbjct: 299  LFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 80/295 (27%), Positives = 113/295 (38%), Gaps = 57/295 (19%)

Query: 1067 LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPP 1126
            LK   + D    R  +       R E +     F + L D+   E   L LQC+VS DP 
Sbjct: 2616 LKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS-DPE 2674

Query: 1127 ATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV 1185
            A ++W  +G  L  + K+  L   G+   V +    PED GLY C      G  E   +V
Sbjct: 2675 AHVVWRKDGVQLGPSDKYDFLHTAGTRGLV-VHDVSPEDAGLYTC----HVGSEETRARV 2729

Query: 1186 TVDDAPASENTKAPEMKSRRPKS-SLPPVLGTESDA------------------------ 1220
             V D       +   M+    +S S   VL  ES +                        
Sbjct: 2730 RVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQG 2789

Query: 1221 ----TVKKKPAPK-----------TPPKAAM-----PPQIIQFPEDQKVRAGESVELFGK 1260
                 V ++ AP               KA++     P  II+  EDQ V  GE VEL  +
Sbjct: 2790 RKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE 2849

Query: 1261 VT--GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1313
            ++  GT P+   W+K RK I++S+   V      + L I  A  +  G YT  VE
Sbjct: 2850 LSRAGT-PV--HWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 1/113 (0%)

Query: 603  KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 662
            +K    + + L    S   AP FL+ LSD  V+ G  VT+  QVS  P  +  W  +G  
Sbjct: 7443 RKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAP 7502

Query: 663  IQESEDFHFEQRGTQHS-LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 714
            ++ S              L I  V  ED G YTC   N+ G V T  VL   E
Sbjct: 7503 LESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAE 7555



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 4/98 (4%)

Query: 513  APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----L 568
            AP+F   L D  V+ GQ   L C V   P  + TW  +G P++ +     +   +    L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521

Query: 569  HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 606
             I   + ED G YTC   NALG V+ +  +   E+ SS
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSS 7559



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)

Query: 1748 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1807
            A AE+ PH    F      + V EGS A F C++ G P P V W KD + + E    ++ 
Sbjct: 104  ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159

Query: 1808 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1850
             +E G  S L I      D   Y  +A N LG A+  A L+V++
Sbjct: 160  VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203



 Score = 52.0 bits (123), Expect = 5e-06
 Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F    +   V  G  A   C+I G P P+V W KD Q +     F++  D D    L 
Sbjct: 10   PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            I D+   D  +Y C+A N++GEA     L V+
Sbjct: 69   ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100



 Score = 51.6 bits (122), Expect = 7e-06
 Identities = 74/357 (20%), Positives = 127/357 (35%), Gaps = 59/357 (16%)

Query: 1109 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIIL---SQEGSLCSVSIEKALPEDR 1165
            V EGK   L C V+ +P    +W  +G+ +   +  ++   +QE  +  +   K    DR
Sbjct: 249  VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ--SDR 306

Query: 1166 GLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV---------- 1213
            GLY C A N  GQ   S  V V +   P  +  +  E++ +   + L  V          
Sbjct: 307  GLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWF 366

Query: 1214 ----------------LGTESDATVKKKPA-------------PKTPPKAAMPPQII-QF 1243
                             GTE   TV+   A              +T  + A+   ++ + 
Sbjct: 367  KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKL 426

Query: 1244 PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQE 1303
            P    VR G++  +F            W++ ++++     + +        LTI     E
Sbjct: 427  PRKTAVRVGDTA-MFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485

Query: 1304 HCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSLTLSWYGSSY-DG 1359
              G    +     G  Q      V     PP   P    +++   SS+ LSW    + + 
Sbjct: 486  DVGQVAFMA----GDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGER 541

Query: 1360 GSAVQSYSIEIWDSANKTW---KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1413
               +  Y +E       TW    E     +    V D+  +  ++FRV A+N +G S
Sbjct: 542  PVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS 598



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 1/79 (1%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
            G TA+FE  + G P+P VTW+++   +    R L       T+SLV+  V  +D G YTC
Sbjct: 6371 GGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTR-LSQQQEGTTYSLVLRHVASKDAGVYTC 6429

Query: 107  EATNGSGARQVTVELTVEG 125
             A N  G      EL V G
Sbjct: 6430 LAQNTGGQVLCKAELLVLG 6448



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
            P+ +  ++DV    G     +  +  DP  ++ W  +   L  +  +   QEG+  S+ +
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 6416

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE 1194
                 +D G+Y C+A+N  GQ  C  ++ V   D+ P SE
Sbjct: 6417 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSE 6456



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 7/93 (7%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
            F ++L D  + EG+ L L C+ S+ D P  + WT +GKTL+ +    LS EG    + I 
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGHRAQLLIT 3155

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
             A  +D G YKC    +AG A  S  V V   P
Sbjct: 3156 GATLQDSGRYKC----EAGGACSSSIVRVHARP 3184



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 73/332 (21%), Positives = 116/332 (34%), Gaps = 24/332 (7%)

Query: 191  QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS---GKASMSAE 247
            +V W KG   +QP  R  V  +   Q+L I G   +D G Y C +  GS     A+    
Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSICPAAATFQVA 4712

Query: 248  LSIQGLDSANRSFVRETKATNSDVR-----KEVTNVISKESKLDSLEAAAKSKNCSS--P 300
            LS   +D A +  +    A   D+            +S+E  LDS+    +    S   P
Sbjct: 4713 LSPASVDEAPQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDGRSQRLP 4772

Query: 301  QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITL--QAARVQPEPRA 358
            Q         +       E       D   T+        T S +T   +A R    P A
Sbjct: 4773 QEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLA 4832

Query: 359  PGLGV-LSPSGEERKRPAP---PRPATFPTRQPGLGSQDVVSKAANRRIPMEG------Q 408
              +G   +PS + +++  P    RP         LG   +   A   +   +G       
Sbjct: 4833 SKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMDKAAVKIQAAFKGYKVRKEM 4892

Query: 409  RDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVR-RQEGSIEVYEDA 467
            +    P F       E +    ++  C V+        W  +G  +   +   I+   D 
Sbjct: 4893 KQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGD- 4951

Query: 468  GSHYLCLLKARTRDSGTYSCTASNAQGQLSCS 499
            G+  L +      D+G Y+C  SN  GQ++ S
Sbjct: 4952 GTCSLLITGLDRADAGCYTCQVSNKFGQVTHS 4983



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 16/125 (12%)

Query: 1092 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE-G 1150
            +S   AP F ++L D  V  G+ + L CQVS+ P A   W+ +G  L+++  +++S    
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516

Query: 1151 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1210
            +   ++I   + ED G+Y C               +V +A  +  T     K+ RP SS 
Sbjct: 7517 NFQLLTILVVVAEDLGVYTC---------------SVSNALGTVTTTGVLRKAERPSSSP 7561

Query: 1211 PPVLG 1215
             P +G
Sbjct: 7562 CPDIG 7566



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 40/182 (21%), Positives = 65/182 (35%), Gaps = 26/182 (14%)

Query: 366  PSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEV 425
            P G E++ P   +P     R  GL S D                    P F  +   + V
Sbjct: 7433 PEGLEKEGPPRKKPGLASFRLSGLKSWDRA------------------PTFLRELSDETV 7474

Query: 426  KENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTY 485
               Q+V   C+VS  P  +  W  +G P+      +          L +L     D G Y
Sbjct: 7475 VLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVY 7534

Query: 486  SCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQ--------DFVLQCSV 537
            +C+ SNA G ++ +  L+          P    V  D  ++  +         +++QCS+
Sbjct: 7535 TCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSL 7594

Query: 538  RG 539
             G
Sbjct: 7595 EG 7596



 Score = 48.1 bits (113), Expect = 8e-05
 Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F K ++DLEV E  +A F C++   P  E  WFK++  +  S  + I+ +E     L + 
Sbjct: 335  FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 1849
            +V  DDDA Y C+       +   AEL V+
Sbjct: 393  NVSADDDAVYICETPEG---SRTVAELAVQ 419



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)

Query: 1751 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 1803
            EEKP        V P   +     +V +GS+  F  K+EG P P V W +++    E   
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413

Query: 1804 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1855
              I  D  G          SL++ DV       YTC A N+ G+A C+A L V  + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473

Query: 1856 GEGEEEE 1862
             + + +E
Sbjct: 5474 EQEKVKE 5480



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 26/87 (29%), Positives = 38/87 (43%)

Query: 32   APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
            AP F+    +  +  G +     +V   P  Q TW ++G P+ S  R L+   ++    L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521

Query: 92   VIHAVHEEDRGKYTCEATNGSGARQVT 118
             I  V  ED G YTC  +N  G    T
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 5/89 (5%)

Query: 1099 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1158
            +F + LQDV   E +K+ L+C++S  P   + W  +G  L+  K + ++ +G+  S++I 
Sbjct: 2167 SFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225

Query: 1159 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
            +    D+G+Y C    DA  A+ S  V V
Sbjct: 2226 RCEFADQGVYVC----DAHDAQSSASVKV 2250



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 54/236 (22%), Positives = 86/236 (36%), Gaps = 16/236 (6%)

Query: 1020 SGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKR 1079
            + PL     A  A ++KP    +P   ++P       ++L   S +      K  V  + 
Sbjct: 4828 TSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMD------KAAVKIQA 4881

Query: 1080 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1139
               G    ++  + +G  P F     D     G  L L+C V+S       W  +G  L 
Sbjct: 4882 AFKGYKVRKEMKQQEG--PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT 4939

Query: 1140 TTKFIILSQEG-SLCSVSIEKALPEDRGLYKCVAKNDAGQ-AECSCQVTVDDAPASENTK 1197
              +   + Q G   CS+ I      D G Y C   N  GQ    +C V       +E++ 
Sbjct: 4940 DGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSS 4999

Query: 1198 APEMKS--RRPKSSLPPVLGTESDATVKKK----PAPKTPPKAAMPPQIIQFPEDQ 1247
              E+    RR    L  +  T+S A V  +     A + P +   P     + ED+
Sbjct: 5000 GGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDE 5055



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 53/231 (22%), Positives = 87/231 (37%), Gaps = 46/231 (19%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1156
            P F+++L D     G+ + L C+V+  P   I W  +GK ++     I++      C++ 
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1216
            ++     D G Y C A + AG      ++ V   P   N      K R    + P V G 
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVN------KVR----ASPFVEGE 6123

Query: 1217 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1276
            ++  T   + AP         PQI  + +   +  G                    KF+ 
Sbjct: 6124 DAQFTCTIEGAPY--------PQIRWYKDGALLTTGN-------------------KFQT 6156

Query: 1277 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1327
              +    + V        L I AA +E  G Y   + N+LGS +A   L +
Sbjct: 6157 LSEPRSGLLV--------LVIRAASKEDLGLYECELVNRLGSARASAELRI 6199



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F++ L+D+ V EG    L+C +SS   A + W      L+      L QEG++  + +  
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSS-VAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRN 3245

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
              P+D G Y C      G    S  +TV   PA
Sbjct: 3246 LRPQDSGRYSC----SFGDQTTSATLTVTALPA 3274



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 63/266 (23%), Positives = 98/266 (36%), Gaps = 24/266 (9%)

Query: 433  FRCEVS-GIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSG--TYSCTA 489
            F C +S  +P  E +W++ G  V+  +    V  D   H L L  A+   +G  T++C  
Sbjct: 4451 FTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRD 4510

Query: 490  SNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 549
            + A  +L+          A +    S +  L   A +      L C  R         + 
Sbjct: 4511 AVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGL-CGYR-------VEVK 4562

Query: 550  NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 609
             G   Q+          E  +    P +   +   A   +G     A   VH  ++ R +
Sbjct: 4563 EGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVGPVG-----AGEPVHLPQTVRLA 4617

Query: 610  EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 669
            E   PV P +P+AP         +V  G  V++ ++V      EVIW      IQ    F
Sbjct: 4618 EPPKPVPP-QPSAP------ESRQVAAGEDVSLELEVVAEAG-EVIWHKGMERIQPGGRF 4669

Query: 670  HFEQRGTQHSLCIQEVFPEDTGTYTC 695
                +G Q  L I+    ED G Y C
Sbjct: 4670 EVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%)

Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
           V   P +    PP  A +   V+ +  +  +   +++ +    VTWLK    L P  +  
Sbjct: 697 VRAAPGLTANKPPAAAAR--EVLARLHEEAQLLAELSDQAAA-VTWLKDGRTLSPGPKYE 753

Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
           V    G +VL +  V +DD G+Y C+   G     ++ +LS+QGL
Sbjct: 754 VQASAGRRVLLVRDVARDDAGLYECVSRGG----RIAYQLSVQGL 794



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 5/138 (3%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGS-LCSV 1155
            P F  K++     EG+     C +   P   I W  +G  L T  KF  LS+  S L  +
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167

Query: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV 1213
             I  A  ED GLY+C   N  G A  S ++ +      A E     ++ +    ++L   
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERA 6227

Query: 1214 LGTESDATVKKKPAPKTP 1231
               E  + +K+   PK P
Sbjct: 6228 -DQEVTSVLKRLLGPKAP 6244



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 26/89 (29%), Positives = 35/89 (39%)

Query: 1758 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1817
            P F + + D  VV G +    C++   P  +  W KD   +  S    I         L 
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522

Query: 1818 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1846
            I  V  +D   YTC   N+LG  T T  L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%)

Query: 1694 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1753
            W K G  +R   R        G   +   TG+        K E+    S + +       
Sbjct: 3128 WTKDGKTLRGSARCQLSH--EGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRV----- 3180

Query: 1754 PHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1812
             H +P  F + ++DLEV+EG AA   C +     P V W   +  +R    + +   E  
Sbjct: 3181 -HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGA 3237

Query: 1813 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1851
               L++ ++   D  +Y+C    S G+ T +A L V  +
Sbjct: 3238 MLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F  KL++    EG    L+C++S   P  + W    +TL+      L Q+G++C + I  
Sbjct: 3276 FIGKLRNKEATEGATATLRCELSKAAP--VEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
                D   Y CV     G+   S  +T+   PA
Sbjct: 3334 LAMVDAAEYSCV----CGEERTSASLTIRPMPA 3362



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 39/155 (25%), Positives = 62/155 (40%), Gaps = 17/155 (10%)

Query: 1049 PMGNAKPDENLKSASKEELKKD-------VKNDVNCKRGHAGTTDNEKRSESQGTAPA-- 1099
            P+   K  E+L+   +  L++D       +        G       E+R+ +  T  A  
Sbjct: 3390 PVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALP 3449

Query: 1100 --FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1157
              F + L++    EG   +L C++S   P  + W    + L+     IL QEG+ C + I
Sbjct: 3450 AKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRDGDRYILRQEGTRCELQI 3507

Query: 1158 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
                  D G Y CV     GQ   S  +T+   PA
Sbjct: 3508 CGLAMADAGEYLCV----CGQERTSATLTIRALPA 3538



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 44/204 (21%), Positives = 71/204 (34%), Gaps = 40/204 (19%)

Query: 45   KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
            +EG  A F+  V    +  V W R+G  +    +F +      + SL I  +  ED G+ 
Sbjct: 1911 EEGGEATFQCVVSP-SDVAVVWFRDGALLQPSEKFAISQS-GASHSLTISDLVLEDAGQI 1968

Query: 105  TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
            T EA   S +  + V                                      E P  F 
Sbjct: 1969 TVEAEGASSSAALRVR-------------------------------------EAPVLFK 1991

Query: 165  TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
             KL    V+E        ++T RP P++ W +    L P   V +  +     L +H V 
Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050

Query: 225  QDDVGVYTCLVVNGSGKASMSAEL 248
              D G + C   +   +A ++ E+
Sbjct: 2051 FADRGFFGCETPDDKTQAKLTVEM 2074



 Score = 40.4 bits (93), Expect = 0.016
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 5/108 (4%)

Query: 160  PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
            P +F   L  + V EG      C ++    P V W  GN  L+P  + S+ ++  M  L 
Sbjct: 3184 PVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSLRQEGAMLELV 3242

Query: 220  IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
            +  +   D G Y+C      G  + SA L++  L +     +R  +AT
Sbjct: 3243 VRNLRPQDSGRYSC----SFGDQTTSATLTVTALPAQFIGKLRNKEAT 3286



 Score = 38.9 bits (89), Expect = 0.047
 Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 5/78 (6%)

Query: 1111 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1170
            E + ++L C     P A + W  +   L  ++   +S EG +  + I + +P D G+Y+C
Sbjct: 2482 ELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC 2540

Query: 1171 VAKNDAGQAECSCQVTVD 1188
                 AG A  S +VTV+
Sbjct: 2541 ----QAGSAHSSTEVTVE 2554



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 46/236 (19%), Positives = 84/236 (35%), Gaps = 49/236 (20%)

Query: 1074 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1133
            + +C+ G    + +   +E +G     +    +V    G   +L C+V+  P   + W  
Sbjct: 1143 EYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQ-PQTEVTWYK 1201

Query: 1134 NGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS 1193
            +GK L ++  + +  +G    + +++    D G Y C    +AG    S Q+ +      
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSC----EAGGQRVSFQLHI------ 1251

Query: 1194 ENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGE 1253
                                                T PKA    + +   E  +  AG 
Sbjct: 1252 ------------------------------------TEPKAVFAKEQLVHNE-VRTEAGA 1274

Query: 1254 SVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1309
            S  L  +V   Q    TW K  K++  S  +++E +    +L +  A Q   G YT
Sbjct: 1275 SATLSCEVAQAQ-TEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYT 1329



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 56/248 (22%), Positives = 89/248 (35%), Gaps = 47/248 (18%)

Query: 20   DPSRVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
            D +   ++ +T  PA FI   RN    EGATA    R        V W +  + +  G R
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATL--RCELSKAAPVEWRKGSETLRDGDR 3317

Query: 79   FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
            + L         L I  +   D  +Y+C      G  + +  LT+               
Sbjct: 3318 YCLRQD-GAMCELQIRGLAMVDAAEYSCVC----GEERTSASLTI--------------- 3357

Query: 139  TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
                         RP      P  F  +L      EG      C+++      V W KG 
Sbjct: 3358 -------------RPM-----PAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRKGR 3397

Query: 199  VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258
              L+   R S+ +   +  L+I G+   D G Y+C+     G+   SA L+++ L +   
Sbjct: 3398 ESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCV----CGEERTSATLTVKALPAKFT 3453

Query: 259  SFVRETKA 266
              +R  +A
Sbjct: 3454 EGLRNEEA 3461



 Score = 37.4 bits (85), Expect = 0.14
 Identities = 37/137 (27%), Positives = 55/137 (40%), Gaps = 21/137 (15%)

Query: 295  KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
            K  S+PQ G SP  A    P PP      SCK++P   P +P L +  +           
Sbjct: 7038 KQGSAPQEGCSPHPAV--APCPPGSFPPGSCKEAP-LVPSSPFLGQPQA----------- 7083

Query: 355  EPRAPGLGVLSPSGEERKRPA----PPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
             P AP     SP  + +  P     P RP   P   PG  SQ   S+ ++ R+       
Sbjct: 7084 -PPAPAKA--SPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGT 7140

Query: 411  SAFPKFESKPQSQEVKE 427
               P  +++  +QE ++
Sbjct: 7141 EPGPSLDAEGWTQEAED 7157



 Score = 37.0 bits (84), Expect = 0.18
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)

Query: 1757 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1816
            +P F + ++ L+  EGS A   C++   P   VVW K    ++ +   +    +     L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946

Query: 1817 IISDVCGDDDAKYTCKAVNSLGEATCT 1843
            ++ D+  +D  +YTC   +    AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)

Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
            + +RD   +E      +C++      +V WFK  Q ++    +++  D      LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351

Query: 1822 CGDDDAKYTCKAVNSLGEATCTAELIVE 1849
              +D+  YTC A    G+   +A+  VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F  +L+     EG    L+C++S   P  + W    ++L+      L Q+G++C + I  
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRDGDRHSLRQDGAVCELQICG 3421

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1192
                D G Y CV     G+   S  +TV   PA
Sbjct: 3422 LAVADAGEYSCV----CGEERTSATLTVKALPA 3450



 Score = 36.6 bits (83), Expect = 0.23
 Identities = 23/80 (28%), Positives = 36/80 (45%)

Query: 47   GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
            G   + E  V    + +  W ++G  +T G    +D    GT SL+I  +   D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971

Query: 107  EATNGSGARQVTVELTVEGS 126
            + +N  G    +  + V GS
Sbjct: 4972 QVSNKFGQVTHSACVVVSGS 4991



 Score = 35.8 bits (81), Expect = 0.40
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            F   L  V   EG +   QC VS    A ++W  +G  L+ ++   +SQ G+  S++I  
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISD 1959

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1191
             + ED G     A+     A  S  + V +AP
Sbjct: 1960 LVLEDAGQITVEAEG----ASSSAALRVREAP 1987



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%)

Query: 1246 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEH 1304
            D + + G+++ L   V     +   W+K   ++ +  H  ++   +G+  L I    +  
Sbjct: 4906 DTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRAD 4965

Query: 1305 CGCYTLLVENKLG 1317
             GCYT  V NK G
Sbjct: 4966 AGCYTCQVSNKFG 4978



 Score = 35.4 bits (80), Expect = 0.52
 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 20/125 (16%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF--EVLQNEDVFT 778
            P F+ +    T  LGQSV ++C ++  P     W +DG  L   +       L+N  + T
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522

Query: 779  LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN-SSARALPRGREPAS--CEDLCGGG 835
            ++             +++   +G  +C VS  L   ++   L +   P+S  C D+  G 
Sbjct: 7523 IL-------------VVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDI--GE 7567

Query: 836  VGADG 840
            V ADG
Sbjct: 7568 VYADG 7572



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)

Query: 1736 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1795
            ES +D + A L       P V  + S  +  +   EG  A F C +    D  VVWF+D 
Sbjct: 1881 ESRDDHTSAQLTVSV---PRVVKFMSG-LSTVVAEEGGEATFQCVVSP-SDVAVVWFRDG 1935

Query: 1796 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1840
              ++ S  F I      + SL ISD+  +D  + T +A  +   A
Sbjct: 1936 ALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSA 1979



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 1100 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1159
            FK+KL+   V E   + L+ +++   P  + WT N   L   K + +  EG+   + +  
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELTRPWPE-LRWTRNATALAPGKNVEIHAEGARHRLVLHN 2048

Query: 1160 ALPEDRGLYKCVAKNDAGQAECSCQV 1185
                DRG + C   +D  QA+ + ++
Sbjct: 2049 VGFADRGFFGCETPDDKTQAKLTVEM 2074



 Score = 35.0 bits (79), Expect = 0.68
 Identities = 22/100 (22%), Positives = 39/100 (39%)

Query: 1235 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1294
            A PP +    ED + + G + +    + G    + TW K   Q+ +S  +  +       
Sbjct: 6354 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 6413

Query: 1295 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1334
            L +     +  G YT L +N  G    +  L V+   + P
Sbjct: 6414 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP 6453



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)

Query: 1759 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1818
            +F   +R  E +EG+ A   C++      E  W K  +S+R+     +  D    C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419

Query: 1819 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1863
              +   D  +Y+C      GE   +A L V+ +     EG   EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 1750 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 1806
            A+ K   K    + + ++E +EG  A F+C++     PEV    W  DD+ +  S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388

Query: 1807 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1848
             + E+G   L++       D   +C+     G+   +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427



 Score = 34.3 bits (77), Expect = 1.2
 Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 12/106 (11%)

Query: 1098 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-------KTTKFIILS--Q 1148
            P   ++     V +G  +    +V   P  T+ W               T  + + S  Q
Sbjct: 5371 PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQ 5430

Query: 1149 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1194
            + SL  + + +   + +G Y C+A N AGQA CS  + V   P  E
Sbjct: 5431 QHSLVLLDVGR---QHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473



 Score = 33.9 bits (76), Expect = 1.5
 Identities = 20/98 (20%), Positives = 39/98 (39%)

Query: 721  PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
            P F        A +G ++ + C +A        WL+DG  L     H      +   +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957

Query: 781  LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 818
            +  +    AG Y   + N+ G+ +    +++  S + A
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEA 4995



 Score = 33.1 bits (74), Expect = 2.6
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1156
            A  F + L+ V    G  + L C++S    A ++W      L+  K   +  EG + S++
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLT 1866

Query: 1157 IEKALPEDRGLYKCVAKNDAGQAECSCQV 1185
            +     ED G Y C +++D   A+ +  V
Sbjct: 1867 VLGLRAEDAGEYVCESRDDHTSAQLTVSV 1895



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)

Query: 1766 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 1823
            +++   G+ A   C++   P  EV W+KD + +  S   ++   E   C+  L++  V  
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230

Query: 1824 DDDAKYTCKA 1833
             D  +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 63   QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
            +V WH+  + I  GGRF +    R    LVI     ED+G+Y C    GS
Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQM-LVIKGFTAEDQGEYHCGLAQGS 4701



 Score = 32.7 bits (73), Expect = 3.4
 Identities = 20/62 (32%), Positives = 28/62 (45%)

Query: 1237 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1296
            PP   +   D     GE+V+L  +VTGT     +W K  K +Q   H  +    +GS   
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072

Query: 1297 IL 1298
            IL
Sbjct: 6073 IL 6074



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)

Query: 1762 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1821
            K + D  V  G      C++     P V W KD ++IR+S+ + +   E     L+I   
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888

Query: 1822 CGDDDAKYTCKAVNSLGEATCTAE 1845
               D  +YTC+   S   A+   E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912



 Score = 32.3 bits (72), Expect = 4.4
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)

Query: 1760 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1819
            F++ +R+ E VEG+ A   C++      E  W K  +++R+   + I   E   C L I 
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508

Query: 1820 DVCGDDDAKYTCKAVNSLGEATCT 1843
             +   D  +Y C        AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 45/163 (27%), Positives = 61/163 (37%), Gaps = 25/163 (15%)

Query: 654 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 713
           V WL +G  +     +  +    +  L +++V  +D G Y C   +  G +  Q  L+VQ
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAYQ--LSVQ 792

Query: 714 EPHDGTQPWFISKPRS---VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF-E 769
                    F+ K  +   V A  G      C    +    VHW +DG  L    GH  E
Sbjct: 793 -----GLARFLHKDMAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMEL----GHSGE 842

Query: 770 VLQNEDVFT---LVLKKVQPWHAGQYEILLKNRVGECSCQVSL 809
               EDV T   LV   V     G Y      RVGE S    L
Sbjct: 843 RFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRL 881



 Score = 32.0 bits (71), Expect = 5.8
 Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)

Query: 1764 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1823
            + D++V EGS+A F C+I       V WF D   +  +   +ID    G   L +  +  
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070

Query: 1824 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 1855
             D      +A +    A           + EL   T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 1772 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 1829
            G++A   C++      EV W+KD + +  S   +I   E   C   L++      D  +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328

Query: 1830 TCKA 1833
            TC+A
Sbjct: 1329 TCEA 1332



 Score = 31.2 bits (69), Expect = 9.9
 Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 1765 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 1822
            R+++   G++A   C++      EV W+KD + +  S   ++   E   C+  L++    
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689

Query: 1823 GDDDAKYTCKA 1833
              D  +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700


>gi|4758194 serine/threonine kinase 17B [Homo sapiens]
          Length = 372

 Score =  147 bits (370), Expect = 1e-34
 Identities = 77/204 (37%), Positives = 131/204 (64%), Gaps = 8/204 (3%)

Query: 1458 QKVSDFYDIEER-LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMN 1514
            +  ++FY +  + LG GKF  V + + K T + +A KF K     +  +  I  EI+++ 
Sbjct: 26   ENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLE 85

Query: 1515 CLHH-PKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL-TERECIKYMRQISEG 1572
                 P+++   + +E  + I+++LE  +GGE+F   + E  E+ +E + I+ ++QI EG
Sbjct: 86   LAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEG 145

Query: 1573 VEYIHKQGIVHLDLKPENIMC--VNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAP 1630
            V Y+H+  IVHLDLKP+NI+   +   G  IK++DFG++R++ +A  L+ + GTPE++AP
Sbjct: 146  VYYLHQNNIVHLDLKPQNILLSSIYPLGD-IKIVDFGMSRKIGHACELREIMGTPEYLAP 204

Query: 1631 EVINYEPIGYATDMWSIGVICYIL 1654
            E++NY+PI  ATDMW+IG+I Y+L
Sbjct: 205  EILNYDPITTATDMWNIGIIAYML 228


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,012,692
Number of Sequences: 37866
Number of extensions: 4204427
Number of successful extensions: 39123
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 814
Number of HSP's successfully gapped in prelim test: 759
Number of HSP's that attempted gapping in prelim test: 16248
Number of HSP's gapped (non-prelim): 13638
length of query: 1863
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1746
effective length of database: 13,817,196
effective search space: 24124824216
effective search space used: 24124824216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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