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Search of human proteins with 116008190
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116008190 myosin light chain kinase isoform 3B [Homo
sapiens]
(1794 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 3618 0.0
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 3594 0.0
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 3437 0.0
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 3413 0.0
gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens] 313 1e-84
gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens] 306 9e-83
gi|110349719 titin isoform N2-A [Homo sapiens] 295 3e-79
gi|110349717 titin isoform novex-2 [Homo sapiens] 295 3e-79
gi|110349713 titin isoform novex-1 [Homo sapiens] 295 3e-79
gi|110349715 titin isoform N2-B [Homo sapiens] 295 3e-79
gi|146219832 myosin light chain kinase 3 [Homo sapiens] 236 2e-61
gi|167466233 myosin light chain kinase family, member 4 [Homo sa... 221 6e-57
gi|14993776 skeletal myosin light chain kinase [Homo sapiens] 220 1e-56
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 200 9e-51
gi|93102361 palladin [Homo sapiens] 193 1e-48
gi|4557511 death-associated protein kinase 3 [Homo sapiens] 191 5e-48
gi|14670383 death-associated kinase 2 [Homo sapiens] 189 3e-47
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 185 4e-46
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 185 4e-46
gi|157785645 SPEG complex locus [Homo sapiens] 166 1e-40
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 158 5e-38
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 158 5e-38
gi|118572606 hemicentin 1 [Homo sapiens] 155 3e-37
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 154 6e-37
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 154 6e-37
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 151 6e-36
gi|4758194 serine/threonine kinase 17B [Homo sapiens] 147 1e-34
gi|109255245 serine/threonine kinase 17a [Homo sapiens] 147 1e-34
gi|27901803 protein serine kinase H1 [Homo sapiens] 144 1e-33
gi|153792294 myopalladin [Homo sapiens] 141 5e-33
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 3618 bits (9382), Expect = 0.0
Identities = 1794/1794 (100%), Positives = 1794/1794 (100%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP
Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
Query: 421 QSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 480
QSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL
Sbjct: 421 QSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 480
Query: 481 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 540
NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS
Sbjct: 481 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 540
Query: 541 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF
Sbjct: 541 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
Query: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 660
HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS
Sbjct: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 660
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA
Sbjct: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
Query: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSL 780
GQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSL
Sbjct: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSL 780
Query: 781 RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKT 840
RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKT
Sbjct: 781 RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKT 840
Query: 841 LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPE 900
LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPE
Sbjct: 841 LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPE 900
Query: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA
Sbjct: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK
Sbjct: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
Query: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS
Sbjct: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
Query: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200
LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC
Sbjct: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200
Query: 1201 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD
Sbjct: 1201 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSF 1320
KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSF
Sbjct: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSF 1320
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDY 1380
NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDY
Sbjct: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDY 1380
Query: 1381 RTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQE 1440
RTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQE
Sbjct: 1381 RTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQE 1440
Query: 1441 ISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQI 1500
ISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQI
Sbjct: 1441 ISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQI 1500
Query: 1501 SEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA 1560
SEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA
Sbjct: 1501 SEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA 1560
Query: 1561 PEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1620
PEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
Sbjct: 1561 PEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1620
Query: 1621 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
Sbjct: 1621 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680
Query: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
Sbjct: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740
Query: 1741 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1741 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 3594 bits (9320), Expect = 0.0
Identities = 1794/1845 (97%), Positives = 1794/1845 (97%), Gaps = 51/1845 (2%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP
Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
Query: 421 QSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 480
QSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL
Sbjct: 421 QSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLL 480
Query: 481 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 540
NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS
Sbjct: 481 NGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 540
Query: 541 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF
Sbjct: 541 EYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
Query: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 660
HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS
Sbjct: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRS 660
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA
Sbjct: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
Query: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSL 780
GQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSL
Sbjct: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSL 780
Query: 781 RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKT 840
RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKT
Sbjct: 781 RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKT 840
Query: 841 LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPE 900
LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPE
Sbjct: 841 LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPE 900
Query: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA
Sbjct: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK
Sbjct: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE
Sbjct: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
Query: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS
Sbjct: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
Query: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200
LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC
Sbjct: 1141 LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200
Query: 1201 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD
Sbjct: 1201 TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSF 1320
KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSF
Sbjct: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSF 1320
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDY 1380
NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDY
Sbjct: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDY 1380
Query: 1381 RTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQE 1440
RTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQE
Sbjct: 1381 RTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQE 1440
Query: 1441 ISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQI 1500
ISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQI
Sbjct: 1441 ISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQI 1500
Query: 1501 SEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA 1560
SEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA
Sbjct: 1501 SEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVA 1560
Query: 1561 PEVINYEPIGYATDMWSIGVICYIL----------------------------------- 1585
PEVINYEPIGYATDMWSIGVICYIL
Sbjct: 1561 PEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEIS 1620
Query: 1586 ----------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTG 1629
NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTG
Sbjct: 1621 DDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTG 1680
Query: 1630 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP 1689
NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP
Sbjct: 1681 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP 1740
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII
Sbjct: 1741 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1800
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1801 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1845
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 3437 bits (8911), Expect = 0.0
Identities = 1739/1863 (93%), Positives = 1749/1863 (93%), Gaps = 69/1863 (3%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
Query: 359 --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389
PGLG V+S + R R + FP +
Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
Query: 390 GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435
SQ+V ++ R + G F E P S EV E+ + C
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 436 ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471
E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
Query: 472 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Query: 532 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
Query: 592 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
Query: 772 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
Query: 832 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
Query: 892 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951
GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
Query: 952 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
Query: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071
HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
Query: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
Query: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
Query: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
Query: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
Query: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
Query: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
Query: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1611
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL
Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILNRLDCTQCLQHPWLMKDTKNMEAKKL 1680
Query: 1612 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1671
SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED
Sbjct: 1681 SKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEED 1740
Query: 1672 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1731
VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE
Sbjct: 1741 VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 1800
Query: 1732 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1791
SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE
Sbjct: 1801 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1860
Query: 1792 EEE 1794
EEE
Sbjct: 1861 EEE 1863
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 3413 bits (8849), Expect = 0.0
Identities = 1739/1914 (90%), Positives = 1749/1914 (91%), Gaps = 120/1914 (6%)
Query: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP
Sbjct: 1 MGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE
Sbjct: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF
Sbjct: 121 LTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRF 180
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG
Sbjct: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP
Sbjct: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA-- 358
QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRA
Sbjct: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
Query: 359 --------------------------PGLG---VLSPSGEERKRPAPPRPATFPTRQPGL 389
PGLG V+S + R R + FP +
Sbjct: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
Query: 390 GSQDVV-SKAANRRIPMEGQRDSAFPKF-ESKPQ-----SQEVKENQTVKFRC------- 435
SQ+V ++ R + G F E P S EV E+ + C
Sbjct: 421 QSQEVKENQTVKFRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTR 480
Query: 436 ------------------------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 471
E LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT
Sbjct: 481 DSGTYSCTASNAQGQLSCSWTLQVERLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGT 540
Query: 472 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV
Sbjct: 541 PVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Query: 532 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG
Sbjct: 601 HEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 660
Query: 592 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 651
NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ
Sbjct: 661 NEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQ 720
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 771
LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADG 840
Query: 772 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL
Sbjct: 841 GGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDL 900
Query: 832 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 891
LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK
Sbjct: 901 LGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKK 960
Query: 892 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 951
GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS
Sbjct: 961 GTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPS 1020
Query: 952 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1011
GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG
Sbjct: 1021 GPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRG 1080
Query: 1012 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1071
HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT
Sbjct: 1081 HAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT 1140
Query: 1072 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131
TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE
Sbjct: 1141 TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1200
Query: 1132 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1191
MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK
Sbjct: 1201 MKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGK 1260
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ
Sbjct: 1261 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1320
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE
Sbjct: 1321 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1380
Query: 1312 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD
Sbjct: 1381 LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1440
Query: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1431
DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA
Sbjct: 1441 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSA 1500
Query: 1432 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1491
KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER
Sbjct: 1501 KEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTER 1560
Query: 1492 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1551
ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV
Sbjct: 1561 ECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKV 1620
Query: 1552 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL-------------------------- 1585
LFGTPEFVAPEVINYEPIGYATDMWSIGVICYIL
Sbjct: 1621 LFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDF 1680
Query: 1586 -------------------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1620
NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM
Sbjct: 1681 DDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYM 1740
Query: 1621 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680
ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV
Sbjct: 1741 ARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1800
Query: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740
AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD
Sbjct: 1801 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1860
Query: 1741 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 1861 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1914
>gi|16950625 myosin light chain kinase isoform 8 [Homo sapiens]
Length = 154
Score = 313 bits (802), Expect = 1e-84
Identities = 154/154 (100%), Positives = 154/154 (100%)
Query: 1641 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1700
MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 60
Query: 1701 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1760
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 61 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 120
Query: 1761 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 121 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 154
Score = 71.6 bits (174), Expect = 6e-12
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 49 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 108
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
I V +D KYTC+A N G T EL VE
Sbjct: 109 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 140
Score = 68.6 bits (166), Expect = 5e-11
Identities = 40/119 (33%), Positives = 58/119 (48%), Gaps = 2/119 (1%)
Query: 533 EKKSSRKSEYLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNG 591
E + +L VA KP P F + + DL+V++GS ++ G P PEV+W +
Sbjct: 27 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 86
Query: 592 NEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
I+ES F + SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 87 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 145
Score = 62.0 bits (149), Expect = 5e-09
Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 5/112 (4%)
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
F E +P + P F+ + + V EG RF CKI G P P+V W K + ++
Sbjct: 36 FLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE 91
Query: 204 SARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 92 SRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 143
Score = 60.5 bits (145), Expect = 1e-08
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 498
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 47 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 106
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 107 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 139
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1081
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 43 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 102
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 103 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 146
Score = 45.4 bits (106), Expect = 5e-04
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 2/124 (1%)
Query: 621 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
T E S +V + V E +P+F R + G + C I G P
Sbjct: 18 TSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPD 77
Query: 681 PTVHWLRDGKALCKDTGHFEVLQNED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
P V W +D +++ +++ HF++ +ED +L++ V +Y N +GE +C
Sbjct: 78 PEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAE 136
Query: 740 LMLQ 743
L+++
Sbjct: 137 LIVE 140
Score = 32.7 bits (73), Expect = 3.3
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 1164 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 44 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 103
Query: 1224 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1258
+ I++ + CG YT N LG L V
Sbjct: 104 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 139
>gi|16950623 myosin light chain kinase isoform 7 [Homo sapiens]
Length = 153
Score = 306 bits (785), Expect = 9e-83
Identities = 153/154 (99%), Positives = 153/154 (99%), Gaps = 1/154 (0%)
Query: 1641 MAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 1700
MAMISGLSGRKSSTGSPTSPLNAEKLESE DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV
Sbjct: 1 MAMISGLSGRKSSTGSPTSPLNAEKLESE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEV 59
Query: 1701 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 1760
VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY
Sbjct: 60 VEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKY 119
Query: 1761 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE
Sbjct: 120 TCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 153
Score = 71.6 bits (174), Expect = 6e-12
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F R+L + EG+ A+F+ ++ GYP+P+V W ++ Q I F +D G SL+
Sbjct: 48 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 107
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
I V +D KYTC+A N G T EL VE
Sbjct: 108 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 67.8 bits (164), Expect = 9e-11
Identities = 39/110 (35%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 542 YLLPVAPSKP-TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
+L VA KP P F + + DL+V++GS ++ G P PEV+W + I+ES F
Sbjct: 35 FLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 94
Query: 601 HFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
+ SL I +V +D YTC+A NS GE A L V+ +G
Sbjct: 95 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEG 144
Score = 63.5 bits (153), Expect = 2e-09
Identities = 37/119 (31%), Positives = 59/119 (49%), Gaps = 5/119 (4%)
Query: 137 SKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK 196
S+ + F E +P + P F+ + + V EG RF CKI G P P+V W K
Sbjct: 28 SEDVSQAFLEAVAEEKPHV----KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFK 83
Query: 197 GNVPLQPSARVSVS-EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD 254
+ ++ S + +++G L I V DD YTC VN G+A+ +AEL ++ ++
Sbjct: 84 DDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 142
Score = 60.5 bits (145), Expect = 1e-08
Identities = 32/93 (34%), Positives = 46/93 (49%), Gaps = 4/93 (4%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR----STCEAGVAE 498
V P FS ++D V+EG C + G P P + W + Q I+ +R E G
Sbjct: 46 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 105
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
L I D +D YTC A N+LG+ +C+A + V
Sbjct: 106 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 138
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Query: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK-FIILSQEG 1081
E P F + ++D+ V EG C++ P ++W + ++++ ++ F I E
Sbjct: 42 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 101
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
CS+ I +D Y C A N G+A C+ ++ V+ E
Sbjct: 102 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 145
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 644 QEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ 703
++PH +P+F R + G + C I G P P V W +D +++ +++ HF++
Sbjct: 42 EKPH--VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDY 98
Query: 704 NED-VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
+ED +L++ V +Y N +GE +C L+++
Sbjct: 99 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 139
Score = 32.7 bits (73), Expect = 3.3
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 7/99 (7%)
Query: 1164 KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
K + P + D +V G + K+ G W K + I+ES H +++ E+G
Sbjct: 43 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 102
Query: 1224 SKLTILAARQEHCG----CYTLLVENKLGSRQAQVNLTV 1258
+ I++ + CG YT N LG L V
Sbjct: 103 NCSLIIS---DVCGDDDAKYTCKAVNSLGEATCTAELIV 138
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1085
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ I +D +Y+ A N G + + V+
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 31020
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
P K +P + +R GE V + +G TW K
Sbjct: 31021 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 31064
Query: 1206 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 31065 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 31124
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1324
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 31125 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 31183
Query: 1325 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1384
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 31184 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 31240
Query: 1385 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1444
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 31241 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 31299
Query: 1445 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1504
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 31300 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 31359
Query: 1505 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1564
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 31360 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 31419
Query: 1565 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1585
++ + ATDMWS+G + Y+L
Sbjct: 31420 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 31479
Query: 1586 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1633
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 31480 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 31538
Query: 1634 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1693
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 31539 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 31586
Query: 1694 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 31587 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 31631
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
DD Y CK VN GE + AEL V+ + E
Sbjct: 31632 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 31663
Score = 179 bits (455), Expect = 2e-44
Identities = 269/1226 (21%), Positives = 462/1226 (37%), Gaps = 191/1226 (15%)
Query: 31 EAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
+APA F+ + I++G EG G P VTW +NG +T R C I T
Sbjct: 7865 KAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQR----CNITTTE 7920
Query: 90 SLVIHAVHE---EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
I + ED G+Y C N SG + ++ +
Sbjct: 7921 KSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILE--------------------- 7959
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
PP F +L V V G C++ G P+ V+W KG+ L+P+
Sbjct: 7960 -------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTT 8006
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKA 266
+ +N + L + V+ +D G Y C N G+ S S L++Q SF R+ +
Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE-QKLPPSFSRQLR- 8064
Query: 267 TNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326
DV++ V + + + E + S W + +P + S
Sbjct: 8065 ---DVQETVGLPVVFDCAISGSEPISVS-------------WYKDGKPLKDSPNVQTSFL 8108
Query: 327 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGE----ERKRP-------A 375
D+ T + KT S+ Q + P +G S S E K P A
Sbjct: 8109 DNTATLN----IFKTDRSLAGQYSCTATNP----IGSASSSARLILTEGKNPPFFDIRLA 8160
Query: 376 PP-----RPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
P A F G V +R I G+ ++ + + +V + +
Sbjct: 8161 PVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDS 8220
Query: 431 VKFRCEGLAVMEVA----------------PSFSSVLKDCAV-IEGQDFVLQCSVRGTPV 473
++ C AV EV PSF+ L + EG F L+ V G+
Sbjct: 8221 GQYTC--YAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQP 8278
Query: 474 PRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
+ W N QP T + L ++ A D G YTC N G C++ +
Sbjct: 8279 ITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIV 8338
Query: 531 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
+ E P KP P+F Q L+ + V +G V ++ V G+ P + WL
Sbjct: 8339 IKE--------------PKKP--PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKA 8382
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH--- 647
G EI+ S+ F L +++V D+G Y C+A N AG T++ +T+++
Sbjct: 8383 GREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVA 8442
Query: 648 --------DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF 699
DG + +F+S+P+S+ + + GDP P V W + G
Sbjct: 8443 PATKKAAVDG-RLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRV 8501
Query: 700 EVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRG--REPA 757
+ Q D L ++ +G Y + N GE V+L + + G R
Sbjct: 8502 FIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEGDLRAML 8561
Query: 758 SCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEA 817
+ G G + D L+ P + + D RG+L+ +Q EE
Sbjct: 8562 KKTPILKKGAGEE-EEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEE 8620
Query: 818 IRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPK---TVSEEER 874
+ E+E+++ R +K + +S + E + +++ Q K V E +
Sbjct: 8621 THRLEIEEIE-RSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDI 8679
Query: 875 KVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAEN----GSSS 930
K++ P+ + KGT K +P+ S+ G + L +N +
Sbjct: 8680 KINYPE----IKLSWYKGTEKL---------EPSDKFEISIDGDRHTLRVKNCQLKDQGN 8726
Query: 931 AETLNAKAVESSKPLSNAQPSGP--LKPVGNAKPAETLK-----PMGNAKP-----AETL 978
+ + S+K L+ +P+ L+ V K +T + N K L
Sbjct: 8727 YRLVCGPHIASAK-LTVIEPAWERHLQDV-TLKEGQTCTMTCQFSVPNVKSEWFRNGRIL 8784
Query: 979 KPMGNAKP--DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
KP G K + + + +++ + + CK T E R E++ F +++Q
Sbjct: 8785 KPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDL-ETSAELRIEAEPI--QFTKRIQ 8841
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
++ V+E + +C+VS D A + W L ++ +G ++I P+D
Sbjct: 8842 NIVVSEHQSATFECEVSFD-DAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDE 8900
Query: 1097 GLYKCVAK-NDAGQAECSCQVTVDDAPASENTKAPEM-KSRRPKSSLPPVLGTESDATVK 1154
G+Y +A+ G+A + ++ + K P++ SR P ++P ++
Sbjct: 8901 GVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMP----------IR 8950
Query: 1155 KKPAPKTPPKAAMP-PQIIQFPEDQK 1179
P + PP A P P ++ PE++K
Sbjct: 8951 AVPPEEIPPVVAPPIPLLLPTPEEKK 8976
Score = 175 bits (444), Expect = 3e-43
Identities = 200/781 (25%), Positives = 316/781 (40%), Gaps = 138/781 (17%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G AS+ + S S +R+ + ++P F + P ++ + G +A FE V G
Sbjct: 6243 GQYSCSASNPLGTASSS---ARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQP 6299
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
++TW ++ + I GG + + C + T L I V + D G+YTC+ATN G + +L
Sbjct: 6300 MRITWSKDNKEIRPGGNYTITC-VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQL 6358
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-GRVVVKEGQMGRF 180
+V+ PPKF KL V K+G+ +
Sbjct: 6359 SVKE----------------------------------PPKFVKKLEASKVAKQGESIQL 6384
Query: 181 SCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN--G 238
CKI+G P+ +V+W + + L S + ++S N + +L I+ + +D G Y C N G
Sbjct: 6385 ECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVG 6444
Query: 239 SGKASMSAELSIQGLDSANRSFVRETKATNSDV-------------------RKEVTNVI 279
S + + + + S V K SDV RK+V N
Sbjct: 6445 DASCSTALTVKAPPVFTQKPSPVGALKG--SDVILQCEISGTPPFEVVWVKDRKQVRN-- 6500
Query: 280 SKESKLDS--LEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPV 337
SK+ K+ S + + N + G A N E ++C S +
Sbjct: 6501 SKKFKITSKHFDTSLHILNLEASDVGEYHCKATN-------EVGSDTCSCSVKFKEPPRF 6553
Query: 338 LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSK 397
++K S + TL V+ G +S + + +V+ +
Sbjct: 6554 VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRG-------------------EVIRE 6594
Query: 398 AANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE--GLAVMEVAPSFSSVLKDCA 455
+ N RI +F + Q + + + K+ C+ A M + +VL+
Sbjct: 6595 SENTRI--------SFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPAR 6646
Query: 456 VIE---------GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQD 503
+IE G F L+C V GTP W +G+ + T VA L I
Sbjct: 6647 IIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPC 6706
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 563
A D G Y+ +N++G+ +C+ V+VH S+ ++P P F++ L D+
Sbjct: 6707 AEMSDKGLYSFEVKNSVGKSNCT--VSVHV------SDRIVP--------PSFIRKLKDV 6750
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
+ G+ V + +VSG+ P V W +GNEI +L + + P DTG
Sbjct: 6751 NAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGI 6810
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
YTC A N AG AVLTVQEP P F P SV G S+ + I G P V
Sbjct: 6811 YTCVAANVAGSDECSAVLTVQEP-----PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKV 6865
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 742
W + + L G + ED T L L +VQP +G Y L+ N G SC L +
Sbjct: 6866 KWFKGSRELVP--GESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 6923
Query: 743 Q 743
+
Sbjct: 6924 K 6924
Score = 166 bits (420), Expect = 2e-40
Identities = 161/707 (22%), Positives = 277/707 (39%), Gaps = 57/707 (8%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 32748 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 32807
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 32808 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 32862
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 32863 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 32922
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
TC V N +G S S +L+I+ + V K S++ + V+ +E + A
Sbjct: 32923 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQK--TSEITPQKKAVVQEEIS----QKA 32976
Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK--TSSSITLQA 349
+S+ + A + S E K S T+ + ++ + T +S +
Sbjct: 32977 LRSEEIKMSEAKSQEKLALKEEASKVLIS--EEVKKSAATSLEKSIVHEEITKTSQASEE 33034
Query: 350 ARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT---FPTRQPGLGSQD-----VVSKAANR 401
R E +A + G+ A AT + L + + V
Sbjct: 33035 VRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTL 33094
Query: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQD 461
I RD SK + VK + E + AP+F S + + EGQ+
Sbjct: 33095 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE----LSDAPAFISQPRSQNINEGQN 33150
Query: 462 FVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAEN 518
+ C + G P P I W N PI + + V L I++A D G YT A+N
Sbjct: 33151 VLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 33210
Query: 519 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
GQ S +A S +LP+ +P+ + L+ D + GS + +VQ+S
Sbjct: 33211 FRGQCSATA------------SLMVLPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMS 33256
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 638
+ + + + F Q +QE F E + + N ++ +
Sbjct: 33257 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESS 33315
Query: 639 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTG 697
++ G P + P ++ G+ + ++CA G+P P V W G+ + ++ G
Sbjct: 33316 TSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQG 33375
Query: 698 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 744
F + +D+ TL++ VQ G Y + L N G S V++ +++
Sbjct: 33376 RFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 33422
Score = 153 bits (387), Expect = 1e-36
Identities = 166/748 (22%), Positives = 293/748 (39%), Gaps = 111/748 (14%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P+F++ P +T +F+ ++G P ++ W ++ + SG + + G+
Sbjct: 5324 LTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFI--GLE 5381
Query: 87 GTFSLV-IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G+ S + +++V G+YTC TN G+ T L V
Sbjct: 5382 GSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTE-------------------- 5421
Query: 146 APAVETRPSIWGECPPKFATKL-GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PPKF KL +VK G R CKI G P+ +V W + L S
Sbjct: 5422 --------------PPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPAS 5467
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
+ ++ + + V++++ ++ +D G + C N +G T
Sbjct: 5468 DKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGS----------------------T 5505
Query: 265 KATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAA-----NSQPQPPRE 319
+ + KE S +++L+ A S C + G+PP+ Q + ++
Sbjct: 5506 SCSTKVIVKEPPVFSSFPPIVETLKNAEVSLEC---ELSGTPPFEVVWYKDKRQLRSSKK 5562
Query: 320 SKLES-----------CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR-APGLGVLSP- 366
K+ S S + S + +++ PR L L+
Sbjct: 5563 YKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVV 5622
Query: 367 SGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP-MEGQRDSAFPKFESKPQSQ-- 423
+GE + A A Q ++V+ ++ N RI +E F K E +
Sbjct: 5623 AGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYI 5682
Query: 424 -EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 482
++K + ++ L V+E A V G+ L+C V GTP + W +G
Sbjct: 5683 CQIKNDGGMRENMATLMVLEPAVIVEKA-GPMTVTVGETCTLECKVAGTPELSVEWYKDG 5741
Query: 483 QPI---QYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 539
+ + Q + + ++ L I +D GTYT +N +G+ SC+A V V ++
Sbjct: 5742 KLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRA---- 5797
Query: 540 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
P F + L + + G+ + +V+G+ P V W H +I
Sbjct: 5798 ------------VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAK 5845
Query: 600 FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 659
+ +L + + D G YTC A N AG +AVLTVQEP P F+ +P
Sbjct: 5846 YQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEP-----PSFVKEPE 5900
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+ G++V + I G P V+W R + L K + + V L L +
Sbjct: 5901 PLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKG-DRCNIYFEDTVAELELFNIDISQ 5959
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNSSA 747
+G+Y ++ N G+ SC L ++ +A
Sbjct: 5960 SGEYTCVVSNNAGQASCTTRLFVKEPAA 5987
Score = 152 bits (385), Expect = 2e-36
Identities = 165/737 (22%), Positives = 270/737 (36%), Gaps = 107/737 (14%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
M + AP L + G AKF ++ P + W + G+ I + C IR
Sbjct: 3450 MEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIR 3505
Query: 87 GT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ SL I D G+YTC+A+N G+ T LTV ++
Sbjct: 3506 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAY---------------- 3549
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PP F ++ + G+ +F C +TG P + W K L P
Sbjct: 3550 ----------------PPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP 3593
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
S +S+ +LE+ + D GVY+C N G AEL I +D + F++E
Sbjct: 3594 SPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII--IDKPH--FIKE 3649
Query: 264 TKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLE 323
+ S + K+V E ++D R + W+ + Q PP + +
Sbjct: 3650 LEPVQSAINKKV----HLECQVDE-------------DRKVTVTWSKDGQKLPPGKD-YK 3691
Query: 324 SCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVL---SPSGEERKRPA----P 376
C + + P+ + S + A + + V PS ++ P+ P
Sbjct: 3692 ICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLP 3751
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
A + G V N+ + F E+ +VK + + CE
Sbjct: 3752 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCE 3811
Query: 437 GL-----------AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI 485
+ V++ PSF L+ ++ G + +LQC V GT I+W + + I
Sbjct: 3812 AVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQI 3871
Query: 486 QYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY 542
+ + R + + L I D G Y C+ N +G+ C A + E
Sbjct: 3872 RSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKE--------- 3922
Query: 543 LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
P F++ + DL + G VT+ V G+ P V W+ I+E
Sbjct: 3923 ----------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKM 3972
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
L I +V G YTC A N AG + L V+EP I + +
Sbjct: 3973 SFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAK-----IIERAELIQ 4027
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
+ G + +AG P W +DG+ L + + + +V L + +GQ
Sbjct: 4028 VTAGDPATLEYTVAGTPELKPKWYKDGRPLVA-SKKYRISFKNNVAQLKFYSAELHDSGQ 4086
Query: 723 YEILLKNRVGECSCQVS 739
Y + N VG SC+ +
Sbjct: 4087 YTFEISNEVGSSSCETT 4103
Score = 152 bits (385), Expect = 2e-36
Identities = 171/747 (22%), Positives = 288/747 (38%), Gaps = 123/747 (16%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E P+FI N ++A F+ V G P +TW ++ Q + + +
Sbjct: 5044 LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISF-VDSV 5102
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
+L I +V G+YTC+A N SG + L V+
Sbjct: 5103 ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQE----------------------- 5139
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
P + K V V E C + G P+ +V WLK + PS S
Sbjct: 5140 -----------PAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFS 5188
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLD-SANRSFVRETKAT 267
+S +N + I V + D G YT V N G S S + ++ LD + SF + K T
Sbjct: 5189 MSFENNVASFRIQSVMKQDSGQYTFKVENDFG--SSSCDAYLRVLDQNIPPSFTK--KLT 5244
Query: 268 NSDVRKEVTNVISKESKLD-SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCK 326
D K + + I E K+ SL +A+ W + + C
Sbjct: 5245 KMD--KVLGSSIHMECKVSGSLPISAQ--------------WFKDGKEISTSAKYRLVCH 5288
Query: 327 DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
+ + + + +++ T + + V + G+ + PP P RQ
Sbjct: 5289 ERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE---------PPSFLVKPGRQ 5339
Query: 387 PGLGSQDVVSKAANRRIP----------------------MEGQRDSAFPKFESKPQSQE 424
+ V KA + P +EG ++F S S+
Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGS--TSFLNLYSVDASKT 5397
Query: 425 VK-----ENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITW 478
+ N C + ++ P F L+ +++ G L+C + G+P R+ W
Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457
Query: 479 LLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 535
N + + R T VA + + + ED G + C A+N G SCS V V E
Sbjct: 5458 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP- 5516
Query: 536 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 595
PV S P PI ++ + ++V++ ++SG PP EV+W + +++
Sbjct: 5517 ---------PVFSSFP--PI-------VETLKNAEVSLECELSGTPPFEVVWYKDKRQLR 5558
Query: 596 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 655
S+ + + S+ I V D G Y C+A N G + ++EP P F+
Sbjct: 5559 SSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP-----PRFV 5613
Query: 656 SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKV 715
SK S+T G+ + +I G V WL++ + + +++ + + E+V TL K
Sbjct: 5614 SKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKA 5673
Query: 716 QPWHAGQYEILLKNRVGECSCQVSLML 742
+P +AG+Y +KN G +LM+
Sbjct: 5674 EPANAGKYICQIKNDGGMRENMATLMV 5700
Score = 151 bits (382), Expect = 5e-36
Identities = 188/860 (21%), Positives = 318/860 (36%), Gaps = 144/860 (16%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHI 501
P F ++G D L+C ++GTP ++W + + ++ + E + +HI
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHI 7458
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+ D G Y C A N +G +C + + AP P F++ LS
Sbjct: 7459 LNVDAADIGEYQCKATNDVGSDTCVGSIALK--------------AP-----PRFVKKLS 7499
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI-QESEDFHFEQRGTQHSLCIQEVFPED 620
D+ + G +V + + G P V+W + EI +ES++ +L V P +
Sbjct: 7500 DISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPAN 7559
Query: 621 TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
G YTC+ N AG A L+V EP + KP S+ + G + + C +AG P
Sbjct: 7560 AGKYTCQIKNDAGMQECFATLSVLEP-----ATIVEKPESIKVTTGDTCTLECTVAGTPE 7614
Query: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 740
+ W +DGK L D +++ V L + V P +G Y ++N VG+ SC SL
Sbjct: 7615 LSTKWFKDGKELTSD-NKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASL 7673
Query: 741 MLQNSSARALPRG--REPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGE 798
+ S R +P R+ L G V + YGS P W E G
Sbjct: 7674 QV---SDRTVPPSFTRKLKETNGLSGSSVVME---CKVYGS-----PPISVSWFHE--GN 7720
Query: 799 DVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRA 858
++ K + +T A+ +E+ D D ++T D+
Sbjct: 7721 EISSGRKYQTTLTDNT-CALTVNMLEESDSGDY--TCIATNMAGSDECS----------- 7766
Query: 859 NLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVL-- 916
P TV E V P +D VL + T + + PP + S L
Sbjct: 7767 ------APLTVREPPSFVQKPDPMD---VLTGTNVTFTSIVKGTPPFSVSWFKGSSELVP 7817
Query: 917 GGKKKLPAENGSSSAETLNAKAVES-------SKPLSNAQPSGPLKPVGNAKPAETL--- 966
G + + E+ + E + +S S A + L AK + L
Sbjct: 7818 GDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDY 7877
Query: 967 -----KPM-------GNAKPAETLKPMG-NAKPDE--NLKSASKEELKKDVKNDV----- 1006
KP+ G + T K G N P + N+ + K + + + V
Sbjct: 7878 SIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQ 7937
Query: 1007 -NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN 1065
NC +A D+ P F ++L+ V V+ G LQCQ++ P + W
Sbjct: 7938 YNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKG 7997
Query: 1066 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
L+ T + ++ ++ + D G Y C A+N G+ S +TV +
Sbjct: 7998 DTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE----- 8052
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1185
+PP + D + G
Sbjct: 8053 ---------------------------------------QKLPPSFSRQLRDVQETVGLP 8073
Query: 1186 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVEN 1245
V ++G++PI+ +W K K +++S +++ +N + L I + G Y+ N
Sbjct: 8074 VVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATN 8133
Query: 1246 KLGSRQAQVNLTVVDKPDPP 1265
+GS + L + + +PP
Sbjct: 8134 PIGSASSSARLILTEGKNPP 8153
Score = 147 bits (371), Expect = 9e-35
Identities = 189/781 (24%), Positives = 307/781 (39%), Gaps = 107/781 (13%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2889 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2945
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2946 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 3005
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 3006 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3065
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3066 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3124
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSL 288
G YT + +G +A+L ++G D RS ++KEV VI K+ +
Sbjct: 3125 GKYTVV----AGGNVSTAKLFVEGRDVRIRS-----------IKKEV-QVIEKQRAVVEF 3168
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR----TAPQTPVLQKTSSS 344
E + + G + + + E ++ S T V + SS
Sbjct: 3169 EVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSS 3228
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG---SQDVVSKAANR 401
+TL +P P+ L L P + +PA QP + + ++S
Sbjct: 3229 VTLYVNAPEP-PQV--LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3285
Query: 402 RIPMEGQRDS-----AFPKFESKPQSQEVKENQTVKFRCEGLAVM--EVA---------- 444
+ +GQ + AFP+ ++ + E K + V L+V EV
Sbjct: 3286 KFLHDGQEYTLLLIEAFPE-DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3344
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHI 501
P+ + L+D EGQ QC V GT + +++W + P ++ R T +L I
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+A PED GTYT +A NA+GQVS +A +++ +S + AP+ + +
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIE 3463
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
L+V G T ++ P W G EI ES+ SL I D
Sbjct: 3464 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 3523
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 681
G YTC+A N G V A LTV E + P F+S+P+S+T +G++ C + G P
Sbjct: 3524 GEYTCKASNEYGSVSCTATLTVTEAY---PPTFLSRPKSLTTFVGKAAKFICTVTGTPVI 3580
Query: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLM 741
W +DG AL + ++ + E+ L L + G Y N+ G CQ L+
Sbjct: 3581 ETIWQKDGAAL-SPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELI 3639
Query: 742 L 742
+
Sbjct: 3640 I 3640
Score = 144 bits (364), Expect = 6e-34
Identities = 165/767 (21%), Positives = 287/767 (37%), Gaps = 115/767 (14%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGY 59
G AS+ K S S + + E P FI L P + +K+ ++E ++ G
Sbjct: 7280 GQYTCYASNIAGKDSCSAQ------LGVQEPPRFIKKLEPSRI-VKQDEFTRYECKIGGS 7332
Query: 60 PEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
PE +V W+++ I +F + + L +H + ED G YTCEA N +G+ +
Sbjct: 7333 PEIKVLWYKDETEIQESSKFRMSF-VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L V+ PP F K + +G
Sbjct: 7392 SLKVKE----------------------------------PPIFRKKPHPIETLKGADVH 7417
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
C++ G P V+W K L+ + + +N + + I V+ D+G Y C N
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV-----------TNVISKESKLDSL 288
G + ++++ A FV++ ++ V KEV +V+ + K + +
Sbjct: 7478 GSDTCVGSIALK----APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIV 7533
Query: 289 EAA-----AKSKNCSSPQRGGSPPWAANSQP-QPPRESKLESCKDSPRTAPQTPVLQKTS 342
+ + S+N ++ Q P A Q ++ ++ C + +++K
Sbjct: 7534 RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE 7593
Query: 343 SSITLQAARVQPEPRAPGLGVLS----PSGEERKRPAPPRPATFPTRQPGLGSQDVVSKA 398
S E G LS G+E + + F +K
Sbjct: 7594 SIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFF-------------NKV 7640
Query: 399 ANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE 458
+ +I DS FE Q+ K++ T + ++ V PSF+ LK+ +
Sbjct: 7641 SGLKIINVAPSDSGVYSFE--VQNPVGKDSCTASLQ---VSDRTVPPSFTRKLKETNGLS 7695
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYAR---STCEAGVAELHIQDALPEDHGTYTCL 515
G V++C V G+P ++W G I R +T L + D G YTC+
Sbjct: 7696 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 7755
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTV 575
A N G CSA +TV E P F+Q + V+ G+ VT T
Sbjct: 7756 ATNMAGSDECSAPLTVRE-------------------PPSFVQKPDPMDVLTGTNVTFTS 7796
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
V G PP V W +E+ + + + L + +V +G YTC N AG+
Sbjct: 7797 IVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKA 7856
Query: 636 RTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD 695
L ++ P F+ + + G+ +++ G P +V W ++G +
Sbjct: 7857 SCTTHLYIKAPAK-----FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINV-TP 7910
Query: 696 TGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 742
+ + E L + AGQY ++N G+ SC +++
Sbjct: 7911 SQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILI 7957
Score = 144 bits (362), Expect = 1e-33
Identities = 170/745 (22%), Positives = 277/745 (37%), Gaps = 109/745 (14%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E I P + + G E V G PE W ++G+ +++ + + I
Sbjct: 6639 LTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITF-IN 6697
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
SL I D+G Y+ E N G TV + V DR
Sbjct: 6698 KVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVS-----------------DRI-- 6738
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
PP F KL V G C+++G V W + + +
Sbjct: 6739 ------------VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPK 6786
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ--------------- 251
S + L + + D G+YTC+ N +G SA L++Q
Sbjct: 6787 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 6846
Query: 252 -GLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAA 310
G+ S +R T K ++ ES SLE Q
Sbjct: 6847 PGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQ--------- 6897
Query: 311 NSQPQPPRESKLESC---KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPS 367
P ES SC D+ + T + K ++ + A E +P + + +
Sbjct: 6898 ------PLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYT 6951
Query: 368 GEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQR---DSAFPKFESKPQSQE 424
G T P + + ++S++ I M + + E Q
Sbjct: 6952 G------------TPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSC 6999
Query: 425 VKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 484
+ EN+ + CE L + P F L+ + G+ LQC V GTP RI+W
Sbjct: 7000 LIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTK 7059
Query: 485 IQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 541
++ A + + VA L I D G Y+C A+N++G V+ SA + + +K
Sbjct: 7060 LRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK------ 7113
Query: 542 YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 601
LP P F + L D+ G V +++G+ P +V W +G +++ +
Sbjct: 7114 --LP--------PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANL- 7162
Query: 602 FEQRGTQHSLCIQEVFPED---TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 658
Q H++ ++ D G Y C A N G + A L + E H+ P+F KP
Sbjct: 7163 --QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSE-HE-VPPFFDLKP 7218
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 718
SV +LG+S C + G + W +D + + + G++++ E+ TL + KV
Sbjct: 7219 VSVDLALGESGTFKCHVTGTAPIKITWAKDNREI-RPGGNYKMTLVENTATLTVLKVGKG 7277
Query: 719 HAGQYEILLKNRVGECSCQVSLMLQ 743
AGQY N G+ SC L +Q
Sbjct: 7278 DAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 142 bits (357), Expect = 4e-33
Identities = 161/731 (22%), Positives = 269/731 (36%), Gaps = 95/731 (12%)
Query: 29 LTEAPAFILPPRNLC-IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+ + PA I+ L + G A E V G PE + W+++G+P+ + ++ +
Sbjct: 4012 IVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFK-NN 4070
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
L ++ D G+YT E +N G+ TV + + + F+ P
Sbjct: 4071 VAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTV------------LDRDIAPFFTKP 4118
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ G C R CKI G +V+W K + S R
Sbjct: 4119 LRNVDSVVNGTC-------------------RLDCKIAGSLPMRVSWFKDGKEIAASDRY 4159
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
++ G LEI V+ +D G +TC N G S L +Q SFV TK
Sbjct: 4160 RIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ----EPPSFV--TKPG 4213
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
+ DV + V K + S + + G + + E L D
Sbjct: 4214 SKDVLPG-SAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSD 4272
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPA----------PP 377
S T + + + A EP A + L PS +K A PP
Sbjct: 4273 S---GTYTCKVSNVAGGVECSANLFVKEP-ATFVEKLEPSQLLKKGDATQLACKVTGTPP 4328
Query: 378 RPATF-----PTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
T+ ++ V A R+ G DS E+ +N+
Sbjct: 4329 IKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEA--------QNEAGS 4380
Query: 433 FRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR--- 489
C + +++ +P F+ K V++ D +L V GTP ITW + ++ R
Sbjct: 4381 DHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK 4440
Query: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
+ + + L I + D G Y C N +G CSA VT+ E
Sbjct: 4441 TFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREP--------------- 4485
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
P F++ + + G + G+ P V WL + +EI E ++
Sbjct: 4486 ----PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVA 4541
Query: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
SL + + + G Y C+A N AG R A+L+V+EP T+ + S+ + G
Sbjct: 4542 SLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITE-----EAVSIDVTQGDPA 4596
Query: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
+ +G T W +DG+ L + +++ + V L + + +G+Y ++N
Sbjct: 4597 TLQVKFSGTKEITAKWFKDGQELTLGS-KYKISVTDTVSILKIISTEKKDSGEYTFEVQN 4655
Query: 730 RVGECSCQVSL 740
VG SC+ +
Sbjct: 4656 DVGRSSCKARI 4666
Score = 142 bits (357), Expect = 4e-33
Identities = 169/741 (22%), Positives = 270/741 (36%), Gaps = 113/741 (15%)
Query: 31 EAPAFILPPRN-LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
E P FI P L ++ G + FE ++ G P+ +V+W+ +G IT+ + + I G
Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDGLA 4917
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
+ I E+ G Y CEA N +G ++EL V+
Sbjct: 4918 TFQISGARVENSGTYVCEARNDAGTASCSIELKVKE------------------------ 4953
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PP F +L V V + C++TG P +VTWLK N ++ S + ++
Sbjct: 4954 ----------PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTL 5003
Query: 210 SEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS 269
+++ + L I + D G Y C+V N G S S ++++ SF+++ + T
Sbjct: 5004 TDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK----EPPSFIKKIENT-- 5057
Query: 270 DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESC 325
T V+ + S A GSPP W + Q ++ S
Sbjct: 5058 ------TTVLKSSATFQSTVA-------------GSPPISITWLKDDQILDEDDNVYISF 5098
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG-LGVLSPSGEERKRPA----PPRPA 380
DS T V S T QA R L V P+ K + P
Sbjct: 5099 VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPM 5158
Query: 381 TFPTRQPGLGS------QDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVK-----ENQ 429
T G +D +R M + + A + +S + + EN
Sbjct: 5159 TLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVEND 5218
Query: 430 TVKFRCEG-LAVME--VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 486
C+ L V++ + PSF+ L + G ++C V G+ W +G+ I
Sbjct: 5219 FGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIS 5278
Query: 487 YA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 543
+ R C L + + ED YTC N G +CS +TV E
Sbjct: 5279 TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP--------- 5329
Query: 544 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 603
P FL + + S V + G PP ++ W + E+
Sbjct: 5330 ----------PSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIG 5379
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVT 662
G+ L + V TG YTC N G +L V EP P F+ K S
Sbjct: 5380 LEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP-----PKFVKKLEASKI 5434
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
G S + C IAG P V W R+ L + + + + V + + + +G
Sbjct: 5435 VKAGDSSRLECKIAGSPEIRVVWFRNEHEL-PASDKYRMTFIDSVAVIQMNNLSTEDSGD 5493
Query: 723 YEILLKNRVGECSCQVSLMLQ 743
+ +N G SC ++++
Sbjct: 5494 FICEAQNPAGSTSCSTKVIVK 5514
Score = 140 bits (353), Expect = 1e-32
Identities = 170/749 (22%), Positives = 289/749 (38%), Gaps = 113/749 (15%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
VD P+F +N GA+ E +V G V W I SG ++
Sbjct: 5791 VDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKY---- 5846
Query: 84 GIRGTFS-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ TFS L ++++ D G YTC A N +G+ + LTV+
Sbjct: 5847 --QTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE------------- 5891
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
PP F + + V G+ F+ I G P +V W +G
Sbjct: 5892 ---------------------PPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGA 5930
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS--- 255
L R ++ ++ + LE+ ++ G YTC+V N +G+AS + L ++ +
Sbjct: 5931 RELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPAAFLK 5990
Query: 256 --------ANRSFVRETKATNS-----DVRKEVTNVISKES-KLDSLEAAAKSKNCSSPQ 301
+S + E+ T + +K+ N+ + E + + E + +S +
Sbjct: 5991 RLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTK 6050
Query: 302 RGGSPPWAANSQPQPPRE--SKLESCKDSPRTAPQ-TPVLQKTSSSITLQAARVQPEPRA 358
R ++ + + R+ L S + P + P+ S++LQ
Sbjct: 6051 RDAG-QYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQC----QVAGT 6105
Query: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFES 418
P + V G+ + RP P F + +V + N+ DS ++
Sbjct: 6106 PEITVSWYKGDTKLRPTPEYRTYF--------TNNVATLVFNK----VNINDSG--EYTC 6151
Query: 419 KPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW 478
K ++ + FR + ++ PSF+ LKD G L C + G+ ++ W
Sbjct: 6152 KAENSIGTASSKTVFR---IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCW 6208
Query: 479 LLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKK 535
+G + + +++ VA L I G Y+C A N LG S SA +T E K
Sbjct: 6209 YRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPK 6268
Query: 536 SSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ 595
S P KP + + V+ G V+G P + W + EI+
Sbjct: 6269 KS-------PFFDIKPVS---------IDVIAGESADFECHVTGAQPMRITWSKDNKEIR 6312
Query: 596 ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFI 655
++ G L I +V D+G YTC+A N G+ A L+V+EP P F+
Sbjct: 6313 PGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP-----PKFV 6367
Query: 656 SK-PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKK 714
K S A G+S+ + C I+G P V W R+ L ++ + + V L + +
Sbjct: 6368 KKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSEL-HESWKYNMSFINSVALLTINE 6426
Query: 715 VQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
+G Y N VG+ SC +L ++
Sbjct: 6427 ASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 132 bits (332), Expect = 3e-30
Identities = 163/739 (22%), Positives = 269/739 (36%), Gaps = 99/739 (13%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
S+ E P F+ + G + V G+ V W ++ + I
Sbjct: 6544 SVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFI 6603
Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
+L + + + GKY C+ N +G R+ + LTV
Sbjct: 6604 DNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE-------------------- 6643
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
P + K + V G C +TG P+ W K L +
Sbjct: 6644 --------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADS 6689
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
+ ++ N + L+I D G+Y+ V N GK++ + + + SF+R+ K
Sbjct: 6690 KHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDR-IVPPSFIRKLK 6748
Query: 266 ATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGG---SPPWAANSQPQPPRESKL 322
+V ++ L+ + + + Q G S P +S + L
Sbjct: 6749 --------DVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800
Query: 323 ESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA-- 380
+ S T T V + S A EP PS E+ P
Sbjct: 6801 SLLEPSD-TGIYTCVAANVAGSDECSAVLTVQEP---------PSFEQTPDSVEVLPGMS 6850
Query: 381 -TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC---- 435
TF + G V +R + + + F ++ + EV+ ++ + C
Sbjct: 6851 LTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTN 6910
Query: 436 --------EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY 487
L V E A +F L D +V G VL+ + GTP ++W+ + I
Sbjct: 6911 DAGSASCTTHLFVKEPA-TFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQ 6969
Query: 488 ARSTCEAGVAE----LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 543
+ C + E L I ++ ED+ Y+CL EN GQ C A V+V E
Sbjct: 6970 SER-CSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEP--------- 7019
Query: 544 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 603
P F++ L ++ + G T+ +V G P + W +++ + + +
Sbjct: 7020 ----------PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQ 7069
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTA 663
+ SL I +V D G Y+C+A NS G V + AVL ++ P+F K + V
Sbjct: 7070 FKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK--LPPFFARKLKDVHE 7127
Query: 664 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
+LG V C I G V W +DG L KD + + +V TL + + H GQY
Sbjct: 7128 TLGFPVAFECRINGSEPLQVSWYKDG-VLLKDDANLQTSFVHNVATLQILQTDQSHIGQY 7186
Query: 724 EILLKNRVGECSCQVSLML 742
N +G S L+L
Sbjct: 7187 NCSASNPLGTASSSAKLIL 7205
Score = 132 bits (332), Expect = 3e-30
Identities = 94/321 (29%), Positives = 141/321 (43%), Gaps = 25/321 (7%)
Query: 425 VKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG-- 482
+ N+ K C ++ F L D ++ +G+ +L+ + GTP +TW NG
Sbjct: 7848 IVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGIN 7907
Query: 483 -QPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 541
P Q T A L I + ED G Y C ENA G+ SCSA + + E
Sbjct: 7908 VTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP------- 7960
Query: 542 YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 601
P F++ L +KV G ++ Q++G P V W +++ + +
Sbjct: 7961 ------------PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYK 8008
Query: 602 FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV 661
R +L +V D+G Y C+A NS GEV LTVQE P F + R V
Sbjct: 8009 MHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQE--QKLPPSFSRQLRDV 8066
Query: 662 TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 721
++G V+ CAI+G +V W +DGK L KD+ + + ++ TL + K AG
Sbjct: 8067 QETVGLPVVFDCAISGSEPISVSWYKDGKPL-KDSPNVQTSFLDNTATLNIFKTDRSLAG 8125
Query: 722 QYEILLKNRVGECSCQVSLML 742
QY N +G S L+L
Sbjct: 8126 QYSCTATNPIGSASSSARLIL 8146
Score = 124 bits (312), Expect = 6e-28
Identities = 156/754 (20%), Positives = 274/754 (36%), Gaps = 130/754 (17%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
S+ + E P F P + +GA E ++G P V+W+++ + + SG ++ + +
Sbjct: 7392 SLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI---M 7448
Query: 86 RGTFSLVIHAVHEE--DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
F IH ++ + D G+Y C+ATN G+ T GS A +
Sbjct: 7449 SENFLTSIHILNVDAADIGEYQCKATNDVGSD------TCVGSIALK------------- 7489
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202
PP+F KL + G+ + I G V W K + +
Sbjct: 7490 ---------------APPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVR 7534
Query: 203 PSARVSVSEKNGMQVLEIHGVN-----------QDDVGVYTCLV---------------- 235
S + +S + L+ V ++D G+ C
Sbjct: 7535 ESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPES 7594
Query: 236 VNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSK 295
+ + + + E ++ G + + ++ K SD + +++ +K S L + A
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKIS-FFNKVSGLKIINVAPSD- 7652
Query: 296 NCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPE 355
S ++ Q ++S S + S RT P + +K + L + V E
Sbjct: 7653 ---------SGVYSFEVQNPVGKDSCTASLQVSDRTVPPS-FTRKLKETNGLSGSSVVME 7702
Query: 356 PRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
+ G +PP ++ + +S + + +
Sbjct: 7703 CKVYG--------------SPPISVSW------FHEGNEISSGRKYQTTLTDNTCALTVN 7742
Query: 416 FESKPQSQE---VKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTP 472
+ S + + N C + PSF V+ G + V+GTP
Sbjct: 7743 MLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTP 7802
Query: 473 VPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWV 529
++W P + E VAEL + D G YTC+ N G+ SC+
Sbjct: 7803 PFSVSWFKGSSELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTT-- 7860
Query: 530 TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 589
+L AP+K F++ L+D + G + + +G PP V W
Sbjct: 7861 ------------HLYIKAPAK-----FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKK 7903
Query: 590 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDG 649
NG + S+ + L I ED G Y C N++G+ A + + EP
Sbjct: 7904 NGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP--- 7960
Query: 650 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 709
P+F+ + V S+G S + C +AG P V W + G + T +++ +V T
Sbjct: 7961 --PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYK-GDTKLRPTTTYKMHFRNNVAT 8017
Query: 710 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
LV +V +G+Y +N VGE S L +Q
Sbjct: 8018 LVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 30151 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 30207
Query: 726 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 779
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 30208 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 30263
Query: 780 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 837
+ W + VRG +++ E R Q L + V+
Sbjct: 30264 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 30321
Query: 838 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 894
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 30322 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 30380
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 953
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 30381 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 30436
Query: 954 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1001
L+ + +K + TL KP K D K ++KE +K
Sbjct: 30437 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 30496
Query: 1002 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 30497 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 30555
Query: 1052 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1111
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 30556 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 30615
Query: 1112 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
S ++ + P P P K
Sbjct: 30616 TSSKLLLQATPQFH---------------------------------PGYPLK------- 30635
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1230
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 30636 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 30691
Query: 1231 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 30692 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 30751
Query: 1291 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 30752 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 30811
Query: 1349 ESELTTVGEKPEEP 1362
S + + E+P
Sbjct: 30812 VSSVVIIKSPFEKP 30825
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000
Query: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 645
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 646 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Query: 691 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1121 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1177
Query: 748 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 806
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1178 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1232
Query: 807 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 863
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1233 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1288
Query: 864 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 912
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1289 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1344
Query: 913 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 966
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1345 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1396
Query: 967 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1026
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1397 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1453
Query: 1027 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1083
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1454 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1513
Query: 1084 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1143
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1514 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1550
Query: 1144 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1203
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1551 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1590
Query: 1204 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1258
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1591 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1650
Query: 1259 VDKPDP------PAGTPCASDIRSSSL 1279
+P+P P GT A +I + L
Sbjct: 1651 FAEPEPERKLIIPRGTYRAKEIAAPEL 1677
Score = 114 bits (284), Expect = 1e-24
Identities = 89/323 (27%), Positives = 136/323 (42%), Gaps = 37/323 (11%)
Query: 435 CEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARST 491
C + ++ PSF + V+ G++ +RGTP ++ W + +
Sbjct: 5883 CRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIY 5942
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 551
E VAEL + + G YTC+ N GQ SC+ + V E P A
Sbjct: 5943 FEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE-----------PAA---- 5987
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
FL+ LSD V G + + +G P V W +G I SE + T
Sbjct: 5988 ----FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIV---TTEKT 6040
Query: 612 CIQEVF---PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 668
CI E+ D G Y+CE N AG A+++ EP P+F+++ + A++G S
Sbjct: 6041 CILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEP-----PYFVTELEPLEAAVGDS 6095
Query: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 728
V + C +AG P TV W + G + T + +V TLV KV +G+Y +
Sbjct: 6096 VSLQCQVAGTPEITVSWYK-GDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAE 6154
Query: 729 NRVGECSCQVSLMLQNSSARALP 751
N +G S + +Q R LP
Sbjct: 6155 NSIGTASSKTVFRIQE---RQLP 6174
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 32353 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 32412
Query: 593 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 613
E+QES D H + GT ++C
Sbjct: 32413 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 32472
Query: 614 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 649
+ VFPE T T EA +S EV++Q T + H
Sbjct: 32473 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 32532
Query: 650 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 32533 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 32592
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 32593 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Query: 744 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 779
+ + ++ R + P +++
Sbjct: 32652 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 32711
Query: 780 LRPGWPARGQGWLEEEDGEDVR--------GVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771
Query: 832 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 885
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831
Query: 886 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 914
S + +K K P P P P+P T D ++
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 32891
Query: 915 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 946
+ GGK KL + G SS+ L KA++ ++
Sbjct: 32892 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 32951
Query: 947 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 998
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 32952 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 33008
Query: 999 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 33009 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 33066
Query: 1059 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 33067 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126
Query: 1119 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178
+ E+ SDA P I P Q
Sbjct: 33127 ----------SKEL----------------SDA-----------------PAFISQPRSQ 33143
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 33144 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 33203
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 33204 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 33263
Query: 1299 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1354
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 33264 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 33321
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEV 1378
G + PK E SD E +V
Sbjct: 33322 AGIRGIPPKIEALPSDISIDEGKV 33345
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 18898 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 18956
Query: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1286
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 18957 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 19016
Query: 1287 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 19017 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 19076
Query: 1346 PSQESELTTVGE--KPEEPKD 1364
P ++ P EPK+
Sbjct: 19077 PLTSPKMVAQFPFGVPSEPKN 19097
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 498
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQ 644
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 110 bits (275), Expect = 1e-23
Identities = 90/359 (25%), Positives = 143/359 (39%), Gaps = 45/359 (12%)
Query: 435 CEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---T 491
C+ ++ P F L+ + L+C V +TW +GQ + +
Sbjct: 3634 CQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKIC 3693
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 551
E +A L I A +D GTY C A N G SCSA VTV E S ++ V PS
Sbjct: 3694 FEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPS-----FVKKVDPSYL 3748
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
P G + ++ G+P +V W N E+ ES ++ L
Sbjct: 3749 MLP-------------GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAIL 3795
Query: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLI 671
I +V ED+G+Y+CEA N G + ++EP P FI G + L+
Sbjct: 3796 DITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP-----PSFIKTLEPADIVRGTNALL 3850
Query: 672 SCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 731
C ++G + W +D K + + + + + + + L + G+YE ++ N V
Sbjct: 3851 QCEVSGTGPFEISWFKDKKQI-RSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEV 3909
Query: 732 GECSCQVSLML------------------QNSSARALPRGREPASCEDLCGGGVGADGG 772
G+C C + +L Q + +A RG EP S + G V + G
Sbjct: 3910 GKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDG 3968
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 13702 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 13761
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 13762 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 13820
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1357
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 13821 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 13880
Query: 1358 KPEEPKDEVEVSD 1370
P P +E SD
Sbjct: 13881 DPPGPPTRLEPSD 13893
Score = 108 bits (270), Expect = 5e-23
Identities = 83/310 (26%), Positives = 133/310 (42%), Gaps = 29/310 (9%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 494
L+ EV P F + G+ +C V GT +ITW + + I+ + T
Sbjct: 7205 LSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVE 7264
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
A L + D G YTC A N G+ SCSA + V E P
Sbjct: 7265 NTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEP-------------------P 7305
Query: 555 IFLQGLSDLKVMDGSQVTM-TVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
F++ L +++ + T ++ G+P +V+W + EIQES F + L +
Sbjct: 7306 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 7365
Query: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 673
+ ED+G YTCEA N+AG + L V+EP P F KP + G V + C
Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP-----PIFRKKPHPIETLKGADVHLEC 7420
Query: 674 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
+ G P V W +D + L + ++++ + ++ + V G+Y+ N VG
Sbjct: 7421 ELQGTPPFHVSWYKDKREL-RSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 7479
Query: 734 CSCQVSLMLQ 743
+C S+ L+
Sbjct: 7480 DTCVGSIALK 7489
Score = 107 bits (266), Expect = 1e-22
Identities = 159/700 (22%), Positives = 240/700 (34%), Gaps = 154/700 (22%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1298 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1357
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1358 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1415
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1416 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1475
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1476 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1535
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1536 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1584
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1585 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1638
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1639 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1695
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
K ++ P F+ K S +K F C +
Sbjct: 1696 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPI--------------- 1729
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512
G P + WL +G+P++ A R E G L A D G
Sbjct: 1730 --------------GDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGII 1775
Query: 513 TCLAENALGQVSCSAWVTVHEKKSSRKSEYL------------------------LPVAP 548
TC A N G SA + V ++KS + L +
Sbjct: 1776 TCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQ 1835
Query: 549 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 608
+ P + ++V++G +V+G P P+V W NG I++S+ F G
Sbjct: 1836 KEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI- 1894
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
H L I + DTG A N G + + L +Q+ D
Sbjct: 1895 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1934
Score = 105 bits (261), Expect = 5e-22
Identities = 82/329 (24%), Positives = 136/329 (41%), Gaps = 32/329 (9%)
Query: 427 ENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ 486
+N C +++ P FSS ++ + L+C + GTP + W + + ++
Sbjct: 5499 QNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLR 5558
Query: 487 YARSTCEAGV---AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 543
++ A +HI + D G Y C A+N +G +C V + E
Sbjct: 5559 SSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE---------- 5608
Query: 544 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE-IQESEDFHF 602
P F+ L+ L V+ G + + G P V WL E I+ESE+
Sbjct: 5609 ---------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRI 5659
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
+L + P + G Y C+ N G A L V EP + K +T
Sbjct: 5660 TFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEP-----AVIVEKAGPMT 5714
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
++G++ + C +AG P +V W +DGK L H N+ + +L + V+ AG
Sbjct: 5715 VTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNK-ISSLRILSVERQDAGT 5773
Query: 723 YEILLKNRVGECSCQVSLMLQNSSARALP 751
Y ++N VG+ SC + + S RA+P
Sbjct: 5774 YTFQVQNNVGKSSCTA---VVDVSDRAVP 5799
Score = 102 bits (253), Expect = 4e-21
Identities = 81/314 (25%), Positives = 133/314 (42%), Gaps = 27/314 (8%)
Query: 434 RCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYAR 489
RC L ++ + + V +G LQ GT W +GQ + +Y
Sbjct: 4568 RCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKI 4627
Query: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
S + V+ L I +D G YT +N +G+ SC A + V + ++P
Sbjct: 4628 SVTDT-VSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINV--------LDLIIP---- 4674
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
P F + L + + GS + + V+G+ P + W + EI SE + F
Sbjct: 4675 ----PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTA 4730
Query: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
L I ++ D+GTYTC A N AG + LTV+EP P+F+ KP+S + V
Sbjct: 4731 FLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP-----PYFVEKPQSQDVNPNTRV 4785
Query: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
+ + G T+ W +D K L V +++ +L L + +G Y L N
Sbjct: 4786 QLKALVGGTAPMTIKWFKDNKELHSGAAR-SVWKDDTSTSLELFAAKATDSGTYICQLSN 4844
Query: 730 RVGECSCQVSLMLQ 743
VG + + +L ++
Sbjct: 4845 DVGTATSKATLFVK 4858
Score = 102 bits (253), Expect = 4e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 26876 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 26935
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 26936 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 26995
Query: 1292 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 26996 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 27052
Query: 1348 QESEL 1352
+ +
Sbjct: 27053 ESDSV 27057
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1167 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 17506 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 17565
Query: 1224 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1283
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 17566 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 17625
Query: 1284 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1342
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 17626 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 17685
Query: 1343 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1400
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 17686 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 17743
Query: 1401 LGSGKFGQV 1409
+GK+ +V
Sbjct: 17744 EVTGKWVRV 17752
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 22540 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 22596
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 22597 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 22656
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 22716
Query: 1341 YGTSEPSQESELTTVGE--KPEEPK 1363
YG EP + + P+ PK
Sbjct: 22717 YGVGEPLESEPVVAKNPFVVPDAPK 22741
Score = 101 bits (251), Expect = 7e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1174 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1233
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 28363 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 28420
Query: 1234 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1293
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 28421 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 28479
Query: 1294 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1352
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 28480 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 28539
Query: 1353 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1402
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 28598
Query: 1403 SGKFGQVFRLVEK 1415
V RLVEK
Sbjct: 28599 KQLTFTVERLVEK 28611
Score = 100 bits (250), Expect = 1e-20
Identities = 82/305 (26%), Positives = 118/305 (38%), Gaps = 29/305 (9%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAEL 499
+ PSF+ LK I+G L+C V G+ I W + Q I + + A L
Sbjct: 4673 IPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFL 4732
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I D GTYTC A N G CS +TV E P F++
Sbjct: 4733 EISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP-------------------PYFVEK 4773
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
V ++V + V G P + W + E+ + T SL +
Sbjct: 4774 PQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKAT 4833
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV-TASLGQSVLISCAIAGD 678
D+GTY C+ N G ++A L V+EP P FI KP V GQS C I G
Sbjct: 4834 DSGTYICQLSNDVGTATSKATLFVKEP-----PQFIKKPSPVLVLRNGQSTTFECQITGT 4888
Query: 679 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738
P V W DG + H + + + T + + ++G Y +N G SC +
Sbjct: 4889 PKIRVSWYLDGNEITAIQKH-GISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSI 4947
Query: 739 SLMLQ 743
L ++
Sbjct: 4948 ELKVK 4952
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 21465 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 21524
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 21525 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 21584
Query: 1292 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 21585 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 21644
Query: 1351 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1402
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 21645 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 21694
Query: 1403 SGKFGQVFRLVEKKT 1417
K GQ + KKT
Sbjct: 21695 -DKAGQRWIKCNKKT 21708
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 22159 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 22218
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 22219 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 22278
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 22279 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 22324
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1289 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1348
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 554
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1349 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1408
Query: 555 -------------------------------------------------IFLQGLSDLKV 565
+F+ K
Sbjct: 1409 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1468
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1527
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1528 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1587
Query: 684 HWLRD 688
WL++
Sbjct: 1588 VWLKN 1592
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1219
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 16116 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 16174
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1279
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 16175 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 16234
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1338
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 16235 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 16294
Query: 1339 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 16295 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 16343
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 23623 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 23679
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1282
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 23680 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 23739
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1341
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 23740 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 23799
Query: 1342 GTSEPSQES 1350
G EP + +
Sbjct: 23800 GVGEPLESA 23808
Score = 99.0 bits (245), Expect = 4e-20
Identities = 98/385 (25%), Positives = 150/385 (38%), Gaps = 54/385 (14%)
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
R SP + + P E E+ A L TSS A ++ +AP
Sbjct: 810 RTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSS-----AQKITKSVKAP-- 862
Query: 362 GVLSPSGEERKRPAPPRPATFP------TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
+ PS E R R P FP T + G + V K I R+ F
Sbjct: 863 -TVKPS-ETRVRAEPTPLPQFPFADTPDTYKSEAGVE--VKKEVGVSITGTTVREERFEV 918
Query: 416 FESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 475
+ E K +T + + + P+ S LK+ VIEG+ L+C + G P P
Sbjct: 919 LHGR----EAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 973
Query: 476 ITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
+TW I+ + + T ++G+A L I++A ED G +TC A N G VS S ++ V
Sbjct: 974 VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Query: 533 -----EKKSSRKSEYLLP----------------------VAPSKPTAPIFLQGLSDLKV 565
EK+++ +E P +P AP F+ K+
Sbjct: 1034 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKL 1093
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQRGTQHSLCIQEVFPEDTGT 623
++G V QV GNP P V W +G + + + ++ + L I F +D G
Sbjct: 1094 VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1153
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHD 648
YT N GE A L + ++
Sbjct: 1154 YTIVVRNKHGETSASASLLEEADYE 1178
Score = 97.4 bits (241), Expect = 1e-19
Identities = 76/307 (24%), Positives = 121/307 (39%), Gaps = 28/307 (9%)
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAG----V 496
M+ AP ++ V G C ++ P R W G+ I Y C +
Sbjct: 3452 MKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI-YESDKCSIRSSKYI 3510
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 556
+ L I D G YTC A N G VSC+A +TV E P F
Sbjct: 3511 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTE-----------------AYPPTF 3553
Query: 557 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
L L G V+G P E IW +G + S ++ +H L + +
Sbjct: 3554 LSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNL 3613
Query: 617 FPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA 676
+D G Y+C+A N G QA L + + +P FI + V +++ + V + C +
Sbjct: 3614 TIQDRGVYSCKASNKFGADICQAELIIID-----KPHFIKELEPVQSAINKKVHLECQVD 3668
Query: 677 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 736
D TV W +DG+ L +++ + + TL + + +G Y N G SC
Sbjct: 3669 EDRKVTVTWSKDGQKL-PPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSC 3727
Query: 737 QVSLMLQ 743
++ ++
Sbjct: 3728 SATVTVR 3734
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 27575 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 27634
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 27635 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 27694
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 27695 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 27742
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 19425
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 19426 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 19473
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1159 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1277
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1336
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 16928 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 16987
Query: 1337 AINVYGTSEPSQESELTT-----VGEKPEEP 1362
A N+YG S+P + V + P++P
Sbjct: 16988 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 17018
Score = 95.9 bits (237), Expect = 3e-19
Identities = 158/697 (22%), Positives = 252/697 (36%), Gaps = 128/697 (18%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2066 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2125
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2126 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2173
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ-MGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2174 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2212
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN-VKTTAKLIVEG---AVVE 2268
Query: 260 FVRETKATN--SDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2269 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2328
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAP---GLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2329 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2387
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423
G+E QP V+ K ++ + + ++ A
Sbjct: 2388 WMKDGQEV--------------QPSDRVHIVIDKQSHMLLIEDMTKEDA----------- 2422
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFS----SVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 479
N + GL+ +S + LKD VIEG VL+C V V + W
Sbjct: 2423 ---GNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWY 2479
Query: 480 LNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
LN + I+ ++ + L I D G Y + +G+V + ++V + K
Sbjct: 2480 LNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLI----VGRVETNCNLSVEKIK- 2534
Query: 537 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
++GL DL + V V++S + +V+W EI+
Sbjct: 2535 -------------------IIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKP 2574
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
S + E G + L + + +D G YT AGE T LTV IS
Sbjct: 2575 SSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAGENMTSGKLTV-------AGGAIS 2623
Query: 657 KP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
KP T + Q + C +A +P WLRDGK L
Sbjct: 2624 KPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHL 2659
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+G + + + K P P I D V GE + + T +W K
Sbjct: 14366 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 14482
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1323
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 14483 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 14541
Query: 1324 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1380
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 14542 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 14600
Query: 1381 RTVTINTEQKVSDFYDIEERLGSGK 1405
+ + K+ + I E++ G+
Sbjct: 14601 KPPLYDGGSKIMGY--IIEKIAKGE 14623
Score = 95.9 bits (237), Expect = 3e-19
Identities = 64/229 (27%), Positives = 117/229 (51%), Gaps = 20/229 (8%)
Query: 531 VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 588
VHE+ K+S+ SE + A K + + + + +G ++ + ++G +V W+
Sbjct: 33021 VHEEITKTSQASEEVRTHAEIKAFS-------TQMSINEGQRLVLKANIAG--ATDVKWV 33071
Query: 589 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
NG E+ SE++ + G+ +L I++ D G TC + G V+ Q LT+ +
Sbjct: 33072 LNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS 33131
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
P FIS+PRS + GQ+VL +C I+G+P P + W ++ + + + + ++ +V+
Sbjct: 33132 DA-PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVY 33189
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757
+L ++ +G+Y I KN G+CS SLM+ LP EP+
Sbjct: 33190 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-------LPLVEEPS 33231
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1180 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 20390 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 20450 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 20508
Query: 1299 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 20509 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 20565
Query: 1355 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 20566 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 20598
Score = 95.5 bits (236), Expect = 4e-19
Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 29/293 (9%)
Query: 475 RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++TW + ++ + T E GVA L+++D D GTY C N G+ S A + V
Sbjct: 31599 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Query: 532 HE-------------KKSSRKSEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 577
KK R+++ + L P + T P++ + G V V +
Sbjct: 31659 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTI 31713
Query: 578 SGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ +P P V W +G +I+ ++ + FE + L I V +D YT A N GE
Sbjct: 31714 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 31773
Query: 635 VRTQAVLTVQ---EPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
+A LTV P D T +P F + GQSV ++G P PT+ W +DG+
Sbjct: 31774 DSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 31833
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
L + + D + L ++ P G Y + N G SCQ L ++
Sbjct: 31834 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 20788 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 20845
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 20846 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 20904
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 20905 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 20964
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1409
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 20965 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 21014
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 25786 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 25842
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 25843 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 25902
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 25903 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 25962
Query: 1341 YGTSEP 1346
YG EP
Sbjct: 25963 YGVGEP 25968
Score = 94.7 bits (234), Expect = 7e-19
Identities = 131/586 (22%), Positives = 204/586 (34%), Gaps = 111/586 (18%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 32433
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN----------------------- 257
+ DD G Y + N G+AS A L + G D
Sbjct: 32434 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 32493
Query: 258 --------------RSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQR 302
S VRE K+ ++ R+ +++ S +++ S KS S R
Sbjct: 32494 YAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTR 32553
Query: 303 GGSPPWAANSQPQPPR------ESKLESCKDSPRTAPQTPVLQK--------------TS 342
AA +P ES SC P L+K T
Sbjct: 32554 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 32613
Query: 343 SSITLQAARVQPEPRAPGLGVLSPS-GEE--------RKRPAPPRPATFPTR----QPGL 389
T + + VQ V+ S G++ +K + T P R +P +
Sbjct: 32614 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRV 32673
Query: 390 GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSS 449
S + V + P E A E+KP E ++ V P +
Sbjct: 32674 KSPEAVKSPKRVKSP-EPSHPKAVSPTETKPTPTEKVQHLPVS----------APPKITQ 32722
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEAGVAELHIQD 503
LK A + L C V + + +TW +G+ ++ + G EL I +
Sbjct: 32723 FLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINN 32780
Query: 504 ALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKSEYLLPVAPS 549
D G Y C G Q A+ ++HEK KS +K+ +
Sbjct: 32781 LTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT 32840
Query: 550 KPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
+P AP + + GL D V S V+ +G P P IW +G I + +
Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
+ L I + D+G YTC NSAG V + LT++ D
Sbjct: 32901 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 32946
Score = 94.4 bits (233), Expect = 9e-19
Identities = 76/291 (26%), Positives = 118/291 (40%), Gaps = 25/291 (8%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512
V G L+ +V GTP + W +G+P+ + R + + VA+L A D G Y
Sbjct: 4028 VTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQY 4087
Query: 513 TCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVT 572
T N +G SC TV ++ AP F + L ++ +
Sbjct: 4088 TFEISNEVGSSSCETTFTVLDRD----------------IAPFFTKPLRNVDSVVNGTCR 4131
Query: 573 MTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSA 632
+ +++G+ P V W +G EI S+ + SL I V D G +TC A NS
Sbjct: 4132 LDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSV 4191
Query: 633 GEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
G + L VQEP P F++KP S G +V + G T+ W + K L
Sbjct: 4192 GSKDSSGALIVQEP-----PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKEL 4246
Query: 693 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
G + + +L L V+ +G Y + N G C +L ++
Sbjct: 4247 VSG-GSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 29458 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 29515
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 29516 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 29574
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 29575 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 29634
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P P ++EV D V TVT+ E+ + D
Sbjct: 29635 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 29661
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 25465
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 25466 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 25524
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 25525 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 25582
Query: 1359 PEEP 1362
P P
Sbjct: 25583 PFSP 25586
Score = 93.2 bits (230), Expect = 2e-18
Identities = 77/338 (22%), Positives = 134/338 (39%), Gaps = 25/338 (7%)
Query: 423 QEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNG 482
Q + N+ C ++ PSF +++ + Q +V G+P ITWL +
Sbjct: 5026 QCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDD 5085
Query: 483 QPIQYARSTCEA---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 539
Q + + + VA L I+ G YTC A+N G C A++ V E
Sbjct: 5086 QILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQ--- 5142
Query: 540 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
++ + V + +T+ V+G P +V WL +G +I S
Sbjct: 5143 ----------------IVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRY 5186
Query: 600 FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 659
F S IQ V +D+G YT + N G A L V + P F K
Sbjct: 5187 FSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD--QNIPPSFTKKLT 5244
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+ LG S+ + C ++G + W +DGK + + + ++ +E +L + ++
Sbjct: 5245 KMDKVLGSSIHMECKVSGSLPISAQWFKDGKEI-STSAKYRLVCHERSVSLEVNNLELED 5303
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757
Y + N G+ +C L ++ + + GR+ A
Sbjct: 5304 TANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQA 5341
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1181 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1232
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 15823 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 15882
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 15941
Query: 1293 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 15942 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 16001
Query: 1352 LTTVGEK--PEEPKDEVEV 1368
TT + P +P ++++
Sbjct: 16002 RTTARDPIYPPDPPIKLKI 16020
Score = 92.8 bits (229), Expect = 3e-18
Identities = 60/220 (27%), Positives = 102/220 (46%), Gaps = 36/220 (16%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F L P ++ + G + F+ V G ++TW ++ + I GG + + + T +L
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTL-VENTATLT 7270
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
+ V + D G+YTC A+N +G + +L V+
Sbjct: 7271 VLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE--------------------------- 7303
Query: 153 PSIWGECPPKFATKLGRV-VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSE 211
PP+F KL +VK+ + R+ CKI G P+ +V W K +Q S++ +S
Sbjct: 7304 -------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 7356
Query: 212 KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ + VLE+H ++ +D G YTC N +G AS S L ++
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 92.4 bits (228), Expect = 3e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1221
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 24705 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 24761
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 24762 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 24821
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 24822 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 24881
Query: 1341 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1369
YG EP + +T KP P EVS
Sbjct: 24882 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 24911
Score = 92.4 bits (228), Expect = 3e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 29723 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 29776
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 29777 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 29836
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1325
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 29837 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 29896
Query: 1326 LPDHEYKFRVRAINVYG 1342
+EY FRV A N +G
Sbjct: 29897 TEGNEYVFRVAATNRFG 29913
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 938 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 995
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 996 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1055
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1056 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1115
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1116 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 92.0 bits (227), Expect = 5e-18
Identities = 80/308 (25%), Positives = 119/308 (38%), Gaps = 37/308 (12%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQD 503
S+ K+ VIE Q V++ V V W +G I + + E + + I +
Sbjct: 3151 SIKKEVQVIEKQRAVVEFEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISE 3209
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 563
D G YT +A +R S L AP P LQ L +
Sbjct: 3210 TRQSDAGEYTFVAGR------------------NRSSVTLYVNAPEPPQV---LQELQPV 3248
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
V G +SG P P++ W + F G +++L + E FPED
Sbjct: 3249 TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3308
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAI 675
YTCEA N G T A L+V+ P D P + I+ + S GQ C +
Sbjct: 3309 YTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV 3368
Query: 676 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 735
+G + +D K K + F + Q ED + L + + P G Y + N VG+ S
Sbjct: 3369 SGTDLKVSWYSKDKK--IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVS 3426
Query: 736 CQVSLMLQ 743
+L L+
Sbjct: 3427 STANLSLE 3434
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 27284 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 27343
Query: 1241 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 27344 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 27462
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1405
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 27463 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 27506
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 23360
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 23361 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1232
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 15409 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 15468
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 15469 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 15527
Query: 1293 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1349
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 15528 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 15587
Query: 1350 SEL 1352
++
Sbjct: 15588 DKV 15590
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1157 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1213
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 17204 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 17263
Query: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1273
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 17264 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 17320
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1332
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 17321 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 17380
Query: 1333 FRVRAINVYG 1342
FRV A N YG
Sbjct: 17381 FRVAAENQYG 17390
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1163 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 21849 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 21906
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 21907 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 21965
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 21966 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 22025
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A N YG P++ +E E+P P
Sbjct: 22026 LAENEYGIGLPAETAESVKASERPLPP 22052
Score = 90.5 bits (223), Expect = 1e-17
Identities = 78/322 (24%), Positives = 129/322 (40%), Gaps = 25/322 (7%)
Query: 425 VKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 484
V N+ K C +++ P+F + D + GQ LQ +VRG+ +TW+ +
Sbjct: 3904 VVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 3963
Query: 485 IQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 541
I+ + + GVA L I D G YTCLAEN G + + V E
Sbjct: 3964 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE-------- 4015
Query: 542 YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 601
P+K ++ ++V G T+ V+G P + W +G + S+ +
Sbjct: 4016 ------PAK-----IIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYR 4064
Query: 602 FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSV 661
+ L D+G YT E N G + TV + P+F R+V
Sbjct: 4065 ISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD--RDIAPFFTKPLRNV 4122
Query: 662 TASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 721
+ + + + C IAG V W +DGK + + + + E +L + +V AG
Sbjct: 4123 DSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAA-SDRYRIAFVEGTASLEIIRVDMNDAG 4181
Query: 722 QYEILLKNRVGECSCQVSLMLQ 743
+ N VG +L++Q
Sbjct: 4182 NFTCRATNSVGSKDSSGALIVQ 4203
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1180 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 16592
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 16651
Query: 1298 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 16652 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 16711
Query: 1357 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1406
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 16712 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 16763
Query: 1407 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1455
K T + + KE + +S +N + K C
Sbjct: 16764 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 16805
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 23011
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 23012 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 23070
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 23071 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 23130
Query: 1359 PEEP 1362
P+ P
Sbjct: 23131 PQPP 23134
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1159 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1209
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 30118 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 30177
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 30178 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 30235
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1328
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 30236 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 30295
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1385
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 30296 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 30355
Query: 1386 NTEQKVSDFY 1395
+ +V+ +Y
Sbjct: 30356 DGGSRVTGYY 30365
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 610
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 731 VGECSCQVSLMLQ 743
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.4 bits (220), Expect = 3e-17
Identities = 60/221 (27%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS 490
+K R + + ++E P F+ L + G++ ++ P P +TW +GQ I+ +
Sbjct: 31676 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 31735
Query: 491 ------TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 544
+ G+ +L I +D YT +A N G+ SC A +TV L
Sbjct: 31736 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV----------TLH 31785
Query: 545 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604
P P+F + L++ + +G V ++VSG PPP + W +G + +
Sbjct: 31786 PPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH 31845
Query: 605 RGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
G ++L I++ PEDTG Y A N+AG QA L V+
Sbjct: 31846 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886
Score = 88.2 bits (217), Expect = 7e-17
Identities = 75/304 (24%), Positives = 124/304 (40%), Gaps = 31/304 (10%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI--- 501
P+F S K G+ C+V GTPV W +G + + + + HI
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILEL 3610
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+ +D G Y+C A N G C A + + +K P F++ L
Sbjct: 3611 SNLTIQDRGVYSCKASNKFGADICQAELIIIDK-------------------PHFIKELE 3651
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
++ +V + QV + V W +G ++ +D+ +L I +D+
Sbjct: 3652 PVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDS 3711
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK-PRSVTASLGQSVLISCAIAGDPF 680
GTY C A N AG A +TV+EP P F+ K S G+S + C + G P
Sbjct: 3712 GTYVCTASNEAGSSSCSATVTVREP-----PSFVKKVDPSYLMLPGESARLHCKLKGSPV 3766
Query: 681 PTVHWLRDGKALCK-DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
V W ++ K L + +T + +E + + KV+ +G Y N VG SC
Sbjct: 3767 IQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVE--DSGSYSCEAVNDVGSDSCSTE 3824
Query: 740 LMLQ 743
++++
Sbjct: 3825 IVIK 3828
Score = 87.8 bits (216), Expect = 9e-17
Identities = 144/684 (21%), Positives = 237/684 (34%), Gaps = 121/684 (17%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIH 221
F +++ + EG F CK++G P P++ W K ++ R + ++G L I
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISK 281
V +D G+YT N G A S +L ++ T S +R +S+
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1412
Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
+ A S SP R + + + ES+LE R VL+
Sbjct: 1413 SP--IRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLE------RLYKPVFVLKPV 1464
Query: 342 S-SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAAN 400
S + Q AR + K P P TF Q +V+ +
Sbjct: 1465 SFKCLEGQTARF-----------------DLKVVGRPMPETFWFHD----GQQIVNDYTH 1503
Query: 401 RRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEGLAVME-----VAPSFSSVLK 452
+ + E S + S E V +N+ + + +E V P F LK
Sbjct: 1504 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLK 1563
Query: 453 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPE 507
+ + EG ++ G P P I WL N P +Y + E G A L I + +
Sbjct: 1564 NVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQ 1623
Query: 508 DHGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP-------- 548
D YT A N G+ C V V + + + ++P AP
Sbjct: 1624 DSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLR 1683
Query: 549 --------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGN 592
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1684 YGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGK 1743
Query: 593 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE------- 645
++ + SL + D+G TC A N G T A L V++
Sbjct: 1744 PLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1803
Query: 646 -------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCA 674
H+G +P + P V G++ C
Sbjct: 1804 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1863
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
+ G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1864 VTGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVI 1921
Query: 735 SCQVSLMLQNSS--ARALPRGREP 756
+V L +Q L R EP
Sbjct: 1922 EHKVKLEIQQREDFRSVLRRAPEP 1945
Score = 87.8 bits (216), Expect = 9e-17
Identities = 69/286 (24%), Positives = 118/286 (41%), Gaps = 46/286 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F ++L+ V V + + L+C+V+ PP + W N + ++++K L+ S+ ++ I
Sbjct: 4955 PTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLHI 5014
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA----SENTKAPEMKSRRPKSSL--- 1141
K P D G Y+C+ N+ G CS +V + + P+ ENT S +S++
Sbjct: 5015 TKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGS 5074
Query: 1142 PPVLGT-------------------ESDATVKKKPAPKTPP------------------- 1163
PP+ T +S AT++ +
Sbjct: 5075 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF 5134
Query: 1164 -KAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P QI++ + V + + L V GT + W+K KQI S + + N
Sbjct: 5135 LLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENN 5194
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1268
+ I + ++ G YT VEN GS L V+D+ PP+ T
Sbjct: 5195 VASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFT 5240
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1163 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1216
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 18597 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 18653
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 18712
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 18713 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 18772
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A+N YG P+ + + EP
Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEP 18799
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 19675 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 19734
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 19735 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 19793
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1328
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 19794 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 19853
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1359
Y FRV A N YG +P + + + P
Sbjct: 19854 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 19884
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1168 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 25104 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 25161
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 25162 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 25220
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 25221 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Query: 1344 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P++ +E V E P P V +V T TI E+ SD
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 25322
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 24036 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 24093
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 24094 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 24152
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 24153 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 24212
Query: 1359 PEEP 1362
P P
Sbjct: 24213 PSPP 24216
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 24383 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 24442
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 24443 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 24490
Score = 86.7 bits (213), Expect = 2e-16
Identities = 66/269 (24%), Positives = 109/269 (40%), Gaps = 60/269 (22%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F QK V +G ++LQC++S PP ++W + K ++ +K ++ + S+ I
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 6517
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
D G Y C A N+ G CSC V
Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSV-------------------------------- 6545
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
K PP+ ++ D G++VEL V G QPI+ W+K R +
Sbjct: 6546 ---------------KFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGE 6590
Query: 1209 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDK 1261
I+ESE+ ++ +N + L + + + G Y ++N G R+ LTV ++K
Sbjct: 6591 VIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEK 6650
Query: 1262 PDP---PAGTPCASD---IRSSSLTLSWY 1284
P+P G P A + + L+ W+
Sbjct: 6651 PEPMTVTTGNPFALECVVTGTPELSAKWF 6679
Score = 85.9 bits (211), Expect = 3e-16
Identities = 73/292 (25%), Positives = 125/292 (42%), Gaps = 41/292 (14%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3216 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3267
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3268 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3324
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3325 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3363
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3364 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3422
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
G+ S +A LS++ A S + E ++ + VI + K++ LE A
Sbjct: 3423 GQVSSTANLSLE----APESILHERIEQEIEMEMKAAPVIKR--KIEPLEVA 3468
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1551
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1552 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1607
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1608 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648
Score = 85.1 bits (209), Expect = 6e-16
Identities = 178/820 (21%), Positives = 302/820 (36%), Gaps = 113/820 (13%)
Query: 367 SGEERKRPAPP--RPATFPTRQPGLGSQDVVSKAANRR-IPMEGQRDSAFPKFESKPQSQ 423
SG+ PA P P PT +P + + ++ +R I M R S ++
Sbjct: 1376 SGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPA 1435
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
+ + ++ E P F +EGQ V G P+P W +GQ
Sbjct: 1436 RMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQ 1495
Query: 484 PI--QYARSTC--EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 539
I Y E G L I A P D G +T +A+N G+ S S +TV + K
Sbjct: 1496 QIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1555
Query: 540 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
P+F++ L ++ + +GS++ M V+ +GNP P+++WL N + I +
Sbjct: 1556 --------------PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1601
Query: 600 FHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 657
GT + +L I +D+ YT A N AG T+ + V+ +P
Sbjct: 1602 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEP----- 1656
Query: 658 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF------TLV 711
R + G + IA +H LR G+ ++ ++ + + F +L
Sbjct: 1657 ERKLIIPRG--TYRAKEIAAPELEPLH-LRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR 1713
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR---EPASCEDLCGGGVG 768
LK+ P H +E L +G+ + V + A R R E C G
Sbjct: 1714 LKRFGPAH---FECRL-TPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1769
Query: 769 ADGG-----GSDRYGSLRPGWP--ARGQGWLEEED--GEDVRGVLKRRVETRQHTEEAIR 819
D G +++YG+ + + L EE E +G+ + R E A+
Sbjct: 1770 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALT 1829
Query: 820 QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKT--------VSE 871
+Q + K+ L + ++ + E FR + +PK + +
Sbjct: 1830 GVTTDQKE------KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRK 1883
Query: 872 EER------KVHSPQQVDFRS--VLAKKGTSKTP---VPEKVPPPKPATPDFRSVLGGKK 920
+R +H VD +S K T++ P + KV DFRSVL
Sbjct: 1884 SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1943
Query: 921 KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 980
+ E L + + +P+ + K V K AE + + +E L+
Sbjct: 1944 EPRPEFHVHEPGKLQFEVQKVDRPVDTTE----TKEVVKLKRAERITHEKVPEESEELRS 1999
Query: 981 MGNAKPDE---------NLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQG 1026
+ +E LKS K+E +++ + H T+ EK++ E +
Sbjct: 2000 KFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKI 2059
Query: 1027 TAPAFK----------------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTL 1069
T P FK +++Q V +G + +V P W NG K
Sbjct: 2060 TIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE 2119
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
++ + E ++C + I ED A N AG+
Sbjct: 2120 RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2159
Score = 84.7 bits (208), Expect = 7e-16
Identities = 150/724 (20%), Positives = 239/724 (33%), Gaps = 89/724 (12%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1759
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1760 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1819
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1820 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1879
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1880 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1937
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1938 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1997
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2057
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438
T PT +P +I + ++ PK + QSQ V + FR
Sbjct: 2058 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVR-- 2100
Query: 439 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC----EA 494
V G P P W NG I+ + E
Sbjct: 2101 -----------------------------VVGKPDPECEWYKNGVKIERSDRIYWYWPED 2131
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
V EL I+D ED + A N G+ S A++ V K+
Sbjct: 2132 NVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ-----------------LI 2174
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F Q L D+ + + + P +V W +G E+ E + + H L I
Sbjct: 2175 TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSIL 2234
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ D Y+C V+T A L V +G F+ + + + S + C
Sbjct: 2235 TIDTSDAEDYSCVLVEDE-NVKTTAKLIV----EGAVVEFVKELQDIEVPESYSGELECI 2289
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ + W + L K G + + L +K V G+Y ++ + C
Sbjct: 2290 VSPENIEG-KWYHNDVEL-KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2347
Query: 735 SCQV 738
++
Sbjct: 2348 KLKM 2351
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 20006 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 20066 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 20125
Query: 1312 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
A+ + T+F V L EY FRV A N YG E
Sbjct: 20126 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 20160
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1168 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 26473 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 26532
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 26533 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 26592
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 26593 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 26652
Query: 1344 SE 1345
S+
Sbjct: 26653 SD 26654
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1169 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 27955 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 28014
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 28015 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 28074
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 28075 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 28134
Query: 1344 SEP 1346
P
Sbjct: 28135 GRP 28137
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 813 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 869
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 722 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 772
Query: 870 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 928
SE K + + S + K T V P+ A+P F K +P
Sbjct: 773 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 829
Query: 929 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 986
A + K LS + + + + A T+KP AE L A
Sbjct: 830 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 886
Query: 987 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1026
+ KS + E+KK+V + GTT E+R E
Sbjct: 887 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 940
Query: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1086
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 941 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 1000
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 1001 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1060
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1061 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1117
Query: 1205 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1118 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 82.4 bits (202), Expect = 4e-15
Identities = 61/234 (26%), Positives = 96/234 (41%), Gaps = 46/234 (19%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F ++L+ V A KK+ L+CQV D T+ W+ +G+ L K + E + ++ I
Sbjct: 3644 PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEI 3703
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
A +D G Y C A N+AG + CS VTV + P
Sbjct: 3704 PLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP-------------------------- 3737
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+ VKK + P + P GES L K+ G+ I TW K K+
Sbjct: 3738 --SFVKK-----------VDPSYLMLP-------GESARLHCKLKGSPVIQVTWFKNNKE 3777
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ ES +++ + + L I + E G Y+ N +GS + + + P
Sbjct: 3778 LSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPP 3831
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1017 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 12987 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 13046
Query: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 13047 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 13091
Query: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
PV E T + + ++ + G S ++ G V
Sbjct: 13092 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 13128
Query: 1196 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1253
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 13129 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 13188
Query: 1254 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 13189 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 13241
Query: 1314 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 13242 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 13301
Query: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1424
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 13302 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 13361
Query: 1425 FFKAYSAKEKENIRQEISIMNCL 1447
+ SA+ K + I+ L
Sbjct: 13362 YLYRVSAENKAGVSDPSEILGPL 13384
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 26198 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 26255
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 26256 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 26314
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 26315 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 26374
Query: 1359 PEEPK 1363
P P+
Sbjct: 26375 PSPPE 26379
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 30907 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 30966
Query: 593 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 650
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 30967 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 31026
Query: 651 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 710
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 31027 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 31085
Query: 711 VLKK-VQPWHAGQYEILLKNRVG 732
V V+ AG Y + KNR G
Sbjct: 31086 VFPNGVERKDAGFYVVCAKNRFG 31108
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 31679 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 31738
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 31739 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 31791
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 31792 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 31893 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 31924
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1237
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272
Query: 1238 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 18273 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 18331
Query: 1298 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1354
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 18332 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 18391
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1395
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 18392 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 18431
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 30649
Query: 673 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 731
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 30650 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 30708
Query: 732 GECSCQVSLMLQN 744
G + + +Q+
Sbjct: 30709 GTVDAILDVEIQD 30721
Score = 81.6 bits (200), Expect = 6e-15
Identities = 75/315 (23%), Positives = 116/315 (36%), Gaps = 74/315 (23%)
Query: 12 ISKTSLSVDPSRVD---SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
ISKT + + D S L++APAFI PR+ I EG F + G P P++ W +
Sbjct: 33110 ISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 33169
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL------- 121
N PI+ + R +SL I D GKYT +A N G T L
Sbjct: 33170 NNLPISISSNVSISRS-RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228
Query: 122 --------------TVEGSFAKQLGQPVVSKTLGD---------------RFSAPAVETR 152
+++GSF+ Q Q SK +F++ + ++
Sbjct: 33229 EPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSM 33288
Query: 153 PSIWGE--------------------------------CPPKFATKLGRVVVKEGQMGRF 180
S+ PPK + + EG++
Sbjct: 33289 SSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTV 33348
Query: 181 SCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
+C TG P P+VTW G + Q R + + + L I V + D G+YT + N
Sbjct: 33349 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 33408
Query: 239 SGKASMSAELSIQGL 253
G S + + I+ +
Sbjct: 33409 FGSDSATVNIHIRSI 33423
Score = 81.3 bits (199), Expect = 8e-15
Identities = 123/536 (22%), Positives = 192/536 (35%), Gaps = 142/536 (26%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 33018 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 33068
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 33069 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 33126
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 33127 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 33156
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 33157 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 33216
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 33217 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 33259
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 33260 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 33304
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 33305 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 33336
Query: 422 SQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481
+ E + V+ VA C+ G P P +TW
Sbjct: 33337 DISIDEGK----------VLTVA---------------------CAFTGEPTPEVTWSCG 33365
Query: 482 GQPI---QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
G+ I + R E + L I D +D G YT N G S SA V +H
Sbjct: 33366 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG--SDSATVNIH 33419
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 29043 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 29159
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 29160 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 29219
Query: 1341 YG-----TSEPSQESELTTVGEKPEEPKD 1364
YG SEP T+ P P++
Sbjct: 29220 YGPGVPVESEPIVARNSFTIPSPPGIPEE 29248
Score = 80.1 bits (196), Expect = 2e-14
Identities = 170/794 (21%), Positives = 285/794 (35%), Gaps = 143/794 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 11818 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 11868
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 11869 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 11927
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 11928 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 11987
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 11988 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 12047
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V W K ++PS + ++L + + D+G YTC G S +L I
Sbjct: 12048 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 12102
Query: 251 QGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAA 310
+ +R + +V + T E D + A K K + Q
Sbjct: 12103 E-----DREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQ--------- 12148
Query: 311 NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEE 370
+ E K+ S QT + ++++ +A ++ +PR +G+L P +
Sbjct: 12149 TPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVK-SSAHLRVKPRV--IGLLRPLKDV 12205
Query: 371 RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
ATF L +D+ + + +E D P+ E K + +++
Sbjct: 12206 TVTAG--ETATFDCE---LSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRD--- 12256
Query: 431 VKFRCEG--------------LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 476
VK G L V E F+ L+D V EG VL+C V ++
Sbjct: 12257 VKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKV 12315
Query: 477 TWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
W NG I ++ + V +L I D PED TYTC A++ + SC+ V
Sbjct: 12316 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 12370
Query: 534 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
P FL+ L+DL+V + ++S +V W +G E
Sbjct: 12371 -----------------PPHVEFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAE 12412
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPW 653
I++ + + +G L I + +D Y+CE + RT +LTV E +
Sbjct: 12413 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLE----EEAV 12464
Query: 654 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 713
F ++ S ++ + C ++ P V W + + + +TG +E+L LV++
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEII-ETGRYEILTEGRKRILVIQ 12522
Query: 714 KVQPWHAGQYEILL 727
AG Y L
Sbjct: 12523 NAHLEDAGNYNCRL 12536
Score = 80.1 bits (196), Expect = 2e-14
Identities = 181/813 (22%), Positives = 280/813 (34%), Gaps = 141/813 (17%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 32370 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 32428
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 32429 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 32488
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 32489 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 32547
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 32548 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 32607
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 32660
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 32661 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 32711
Query: 328 SPRTAPQ--TPVLQ-KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAP-----PRP 379
P +AP T L+ + S I V+ G++ K
Sbjct: 32712 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 32771
Query: 380 ATFPTRQPGLGSQDV---------VSKAANRRIPMEGQRDSAFPKFESK----PQSQEVK 426
T+ + L D + + GQ + + SK +S +
Sbjct: 32772 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 32831
Query: 427 ENQTVKFRCEGLAVMEVA--PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRIT--WLLNG 482
TV + E A ++ P + L+D V D V + +V+ T PR T W +G
Sbjct: 32832 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTV--SSDSVAKFAVKATGEPRPTAIWTKDG 32889
Query: 483 QPI----QYARSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 537
+ I +Y S + G E+H D D G YTC +N+ G VS S +T+ K +
Sbjct: 32890 KAITQGGKYKLSEDKGGFFLEIHKTDT--SDSGLYTCTVKNSAGSVSSSCKLTIKAIKDT 32947
Query: 538 RKSEY-LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
+ + P +Q K + ++ M+ ++ +++
Sbjct: 32948 EAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS---EAKSQEKLALKEEASKVLI 33004
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
SE+ ++ SL V E T T ++ EVRT A + S
Sbjct: 33005 SEEV---KKSAATSLEKSIVHEEITKTS-----QASEEVRTHAEIKA-----------FS 33045
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
S+ GQ +++ IAG V W+ +G L + + D TL +K+
Sbjct: 33046 TQMSINE--GQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQ-TLTIKQAS 33100
Query: 717 PWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 749
G + K + G CQ L L + A
Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDA 33133
Score = 79.7 bits (195), Expect = 2e-14
Identities = 54/230 (23%), Positives = 92/230 (40%), Gaps = 47/230 (20%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+F +KL+DV+ G ++L+C+VS P ++ W +G + + S ++C++++
Sbjct: 6741 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 6800
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
P D G+Y CVA N AG ECS +TV + P+ E T
Sbjct: 6801 SLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQT--------------------- 6839
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
P+ +V G S+ + GT P W K ++
Sbjct: 6840 --------------------------PDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE 6873
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ E + + ++L + + G Y+ LV N GS +L V
Sbjct: 6874 LVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFV 6923
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 21078 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 21137
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 21138 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 21197
Query: 1301 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1342
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 21198 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 21240
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1669 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1728
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1272 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1330
Query: 1729 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1331 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1382
Score = 79.0 bits (193), Expect = 4e-14
Identities = 148/719 (20%), Positives = 276/719 (38%), Gaps = 111/719 (15%)
Query: 35 FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVI 93
F+ P +L ++E A+FE + +V W ++G I G ++ D +G LVI
Sbjct: 12376 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVI 12432
Query: 94 HAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRP 153
+ +D +Y+CE + +TV L E F K L VS+T
Sbjct: 12433 NKCLLDDEAEYSCEVRTARTSGMLTV-LEEEAVFTKNLANIEVSET-------------- 12477
Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
+ C+++ +P +V W KG+ + + R + +
Sbjct: 12478 ----------------------DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEG 12514
Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNG--SGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
++L I + +D G Y C + + GK + EL+ + + + E +
Sbjct: 12515 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAEFISKPQNLEILEGE------ 12567
Query: 272 RKEVTNVISKES-----KLD--SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324
+ E ISKES K D +LE+ K + ++ A Q + +
Sbjct: 12568 KAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGA 12627
Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384
R A V++K + L+ RV+ + ++ G + K A F +
Sbjct: 12628 A----RAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKW-FRNEEAIFDS 12682
Query: 385 RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVA 444
+ + +D+V R ++ Q + + + + + VK + E L ++E
Sbjct: 12683 SKYIILQKDLVYTLRIRDAHLDDQAN--YNVSLTNHRGENVKSAANLIVEEEDLRIVEP- 12739
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---I 501
LKD +E + C V V + W NG+ + + H I
Sbjct: 12740 ------LKDIETMEKKSVTFWCKVNRLNVT-LKWTKNGEEVPFDNRVSYRVDKYKHMLTI 12792
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+D D G Y VT + KS +E L+ AP++ F++ L
Sbjct: 12793 KDCGFPDEGEYI---------------VTAGQDKSV--AELLIIEAPTE-----FVEHLE 12830
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D V + + Q+S V W NG EI+E + + FE+ G+ H L I++ +D
Sbjct: 12831 DQTVTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDE 12889
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE-PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Y C + +++A L V+E P + +P P+ + + G V+ + D
Sbjct: 12890 CEYAC----GVEDRKSRARLFVEEIPVEIIRP-----PQDILEAPGADVVFLAELNKDKV 12940
Query: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
V WLR+ + + H +++ + L + ++P G+Y + K++ +++
Sbjct: 12941 -EVQWLRNNMVVVQGDKH-QMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELA 12997
Score = 78.6 bits (192), Expect = 5e-14
Identities = 67/283 (23%), Positives = 111/283 (39%), Gaps = 60/283 (21%)
Query: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGS 1082
+ Q P+F ++L+DV G ++ C +S P ++ W +GK LK + + S +
Sbjct: 8051 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 8110
Query: 1083 LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP 1142
+++I K G Y C A N G A S ++ + +E P R L
Sbjct: 8111 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL-----TEGKNPPFFDIR-----LA 8160
Query: 1143 PVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1202
PV DA V GES + VTGTQPI +W
Sbjct: 8161 PV-----DAVV-----------------------------GESADFECHVTGTQPIKVSW 8186
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
K ++I+ ++ EN + LT+L + G YT N++G L + ++
Sbjct: 8187 AKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERL 8246
Query: 1263 DPPAGTPCASD----------------IRSSSLTLSWYGSSYD 1289
PP+ T S+ S +T++WY ++ +
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIE 8289
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1156 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1207
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 14664 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 14721
Query: 1208 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1241
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 14722 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 14781
Query: 1242 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1301
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 14782 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 14840
Query: 1302 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 14841 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 14898
Query: 1359 PEEPKD 1364
P P D
Sbjct: 14899 PFGPPD 14904
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1159 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 13383 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 13442
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 13443 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 13501
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1335
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 13502 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 13561
Query: 1336 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1364
A N G EP+ E ++T P+ P++
Sbjct: 13562 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 13593
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 28546 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 28605
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 28637
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+K+ T + Q+I +AG + ++G TW +
Sbjct: 28638 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 28687
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1268
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 28688 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 28747
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1327
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 28748 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
EY FRV + N +G S+P + + + + E P P
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 28840
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 23230 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 23289
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y N GQ S ++ D P + K P
Sbjct: 23290 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 23332
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
D + + PP QI + ++ T W
Sbjct: 23333 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 23376
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1263
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 23377 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 23424
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1316
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 23425 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 23478
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 23479 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 23524
Score = 76.6 bits (187), Expect = 2e-13
Identities = 66/242 (27%), Positives = 101/242 (41%), Gaps = 22/242 (9%)
Query: 13 SKTSLSVDPSRVDS----MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
+ SLSV+ V S MP+ PA I P ++ EG A+F+ RV G + +V+W+
Sbjct: 3322 TSASLSVEVPEVVSPDQEMPVYP-PAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYS 3379
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFA 128
+ I RF T+ L I + ED G YT A+N G T L++E
Sbjct: 3380 KDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP-- 3436
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
L +R +E + + P K+ + V G + +F+C+I P
Sbjct: 3437 --------ESILHER-----IEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAP 3483
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
+ W K + S + S+ + LEI D G YTC N G S +A L
Sbjct: 3484 NVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATL 3543
Query: 249 SI 250
++
Sbjct: 3544 TV 3545
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 12825 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 12883
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1137
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 12884 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 12943
Query: 1138 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1172
++++ V G + + K + + A P+I
Sbjct: 12944 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 13003
Query: 1173 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1232
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 13004 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 13060
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 13061 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 13119
Query: 1293 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1349
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 13120 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 13178
Query: 1350 SELTTVGEKPEEPKDEVEVSDDD 1372
K + P + V+ D
Sbjct: 13179 DNPVEARSKYDVPGPPLNVTITD 13201
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1652 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1710
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 905 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 964
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 965 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 1023
Query: 1771 ATCTAELIVETMEEGEGE 1788
+ + L V+ EE E E
Sbjct: 1024 VSTSCYLAVQVSEEFEKE 1041
Score = 76.3 bits (186), Expect = 3e-13
Identities = 62/234 (26%), Positives = 97/234 (41%), Gaps = 48/234 (20%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+F + L+ + G LLQC+VS P I W + K ++++K L + SL + I
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEI 3890
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
D G Y+CV N+ G +C C T
Sbjct: 3891 FSFNSADVGEYECVVANEVG--KCGCMAT------------------------------- 3917
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+K+ PP ++ +D G++V L V G++PI+ TWMK ++
Sbjct: 3918 --HLLKE------------PPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEV 3963
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
I+E +K+ S + L I + G YT L EN+ GS Q V +V +P
Sbjct: 3964 IREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGS-QTSVGELIVKEP 4016
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 983 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1036
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 14335 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 14394
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 14395 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 14454
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1156
G+Y +N G A S V V P ++K+ SD T
Sbjct: 14455 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 14496
Query: 1157 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PP+ G PI ++ R++ ++
Sbjct: 14497 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 14528
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1274
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 14529 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 14588
Query: 1275 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1326
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 14589 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 14645
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1373
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 14646 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 14696
Score = 75.1 bits (183), Expect = 6e-13
Identities = 68/321 (21%), Positives = 116/321 (36%), Gaps = 53/321 (16%)
Query: 998 LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPP 1057
L + D C+ +A + + S P F++K + +G + L+C++ PP
Sbjct: 7368 LSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPP 7427
Query: 1058 ATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAEC----- 1112
+ W + + L++ K + E L S+ I D G Y+C A ND G C
Sbjct: 7428 FHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIA 7487
Query: 1113 ----------------------SCQVTVDDAPA-----------------------SENT 1127
Q T++ A SEN
Sbjct: 7488 LKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENI 7547
Query: 1128 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1187
+ P ++ ++DA +++ A + P I++ PE KV G++
Sbjct: 7548 ATLQFSRVEPANAGKYTCQIKNDAGMQECFATLS---VLEPATIVEKPESIKVTTGDTCT 7604
Query: 1188 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1247
L V GT ++ W K K++ K+ S L I+ G Y+ V+N +
Sbjct: 7605 LECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPV 7664
Query: 1248 GSRQAQVNLTVVDKPDPPAGT 1268
G +L V D+ PP+ T
Sbjct: 7665 GKDSCTASLQVSDRTVPPSFT 7685
Score = 74.7 bits (182), Expect = 7e-13
Identities = 69/308 (22%), Positives = 120/308 (38%), Gaps = 73/308 (23%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F V + ++ L+C++S PP ++W + + L+++K ++ + S+ I
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHI 5576
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
D G Y C A+N+ G C C
Sbjct: 5577 LNVDTSDIGEYHCKAQNEVGSDTCVC---------------------------------- 5602
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
TVK K PP+ + V AGE EL + G QPI W+K +++
Sbjct: 5603 ---TVKLKE----------PPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEE 5649
Query: 1209 -IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVDK 1261
I+ESE++++ EN + L A + G Y ++N G R+ L +V+K
Sbjct: 5650 VIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEK 5709
Query: 1262 PDP---PAGTPCASDIR---SSSLTLSWYG-------------SSYDGGSAVQSYSIEIW 1302
P G C + + + L++ WY S Y+ S+++ S+E
Sbjct: 5710 AGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQ 5769
Query: 1303 DSANKTWK 1310
D+ T++
Sbjct: 5770 DAGTYTFQ 5777
Score = 74.3 bits (181), Expect = 1e-12
Identities = 59/236 (25%), Positives = 93/236 (39%), Gaps = 29/236 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA LQD +EG+ QC+VS + W K +K ++F ++Q + I
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+A PED G Y VA N GQ + ++++ P+S L + E
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLE----------------APESILHERIEQE 3447
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+ +K P K E +V G + ++ + W K ++
Sbjct: 3448 IEMEMKAAPVIKRKI------------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGRE 3495
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
I ES+ + +S+ S L IL + CG YT N+ GS LTV + P
Sbjct: 3496 IYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1155
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 26546 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 26591
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 26592 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 26641
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1275
+EN + + + S V L P PP+ TP +++
Sbjct: 26642 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 26682
Query: 1276 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1333
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 26683 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 26742
Query: 1334 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 26743 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 26801
Query: 1394 FYDIEER 1400
Y +E R
Sbjct: 26802 -YIVERR 26807
Score = 73.2 bits (178), Expect = 2e-12
Identities = 87/395 (22%), Positives = 147/395 (37%), Gaps = 84/395 (21%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+F +KL+ + +G + L+C V+ P +I W + + + ++ S + + I
Sbjct: 4675 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 4734
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ D G Y C A N AG +CS +TV +
Sbjct: 4735 SQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------------------- 4766
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
PP ++ P+ Q V V+L V GT P+T W K K+
Sbjct: 4767 -------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE 4807
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV------VDKP 1262
+ V + + L + AA+ G Y + N +G+ ++ L V + KP
Sbjct: 4808 LHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKP 4867
Query: 1263 DP------PAGTPCASDIRSS-SLTLSWYGSSYDGG--SAVQSYSIEIWDSANKTWKELA 1313
P T I + + +SWY DG +A+Q + I D LA
Sbjct: 4868 SPVLVLRNGQSTTFECQITGTPKIRVSWY---LDGNEITAIQKHGISFIDG-------LA 4917
Query: 1314 TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL----TTVGE-KPEE--PKDEV 1366
T F + ++ + A N GT+ S E ++ T + E KP E +V
Sbjct: 4918 T-----FQISGARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDV 4972
Query: 1367 EVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERL 1401
E+ + P + + N E + S Y + +R+
Sbjct: 4973 ELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV 5007
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1259
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 30267 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 30326
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1317
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 30327 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 30386
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1368
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 30387 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 30439
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 15098 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 15153
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1278
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 15154 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 15213
Query: 1279 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1338
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 15214 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 15272
Query: 1339 NVYGTSEPSQESELTTV 1355
N +G P + + V
Sbjct: 15273 NKFGCGPPVEIGPILAV 15289
Score = 72.0 bits (175), Expect = 5e-12
Identities = 59/235 (25%), Positives = 95/235 (40%), Gaps = 48/235 (20%)
Query: 1029 PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
P F +KL+ VA +G+ + L+C++S P + W N L + +S S+ ++
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLT 6423
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
I +A ED G Y C A N G A CS +TV KAP + +++P
Sbjct: 6424 INEASAEDSGDYICEAHNGVGDASCSTALTV---------KAPPVFTQKPS--------- 6465
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
P A+ G V L +++GT P W+K RK
Sbjct: 6466 ---------------PVGAL--------------KGSDVILQCEISGTPPFEVVWVKDRK 6496
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
Q++ S+ K+ + + L IL G Y N++GS ++ + P
Sbjct: 6497 QVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPP 6551
Score = 72.0 bits (175), Expect = 5e-12
Identities = 103/475 (21%), Positives = 169/475 (35%), Gaps = 98/475 (20%)
Query: 924 AENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKP--MGNAKPAETL--K 979
A NG A A V++ P+ +PS PVG K ++ + + P E + K
Sbjct: 6439 AHNGVGDASCSTALTVKAP-PVFTQKPS----PVGALKGSDVILQCEISGTPPFEVVWVK 6493
Query: 980 PMGNAKPDENLKSASKE--------ELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAF 1031
+ + K SK L+ + +CK + +D S P F
Sbjct: 6494 DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRF 6553
Query: 1032 KQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIEK 1090
+KL D G + L+ V P +++W + G+ ++ ++ +S ++ ++ +
Sbjct: 6554 VKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGS 6613
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1150
+ G Y C KNDAG ECS +TV +
Sbjct: 6614 PEASNSGKYICQIKNDAGMRECSAVLTVLE------------------------------ 6643
Query: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
P +II+ PE V G L VTGT ++ W K +++
Sbjct: 6644 -----------------PARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELS 6686
Query: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPC 1270
+ + L I A G Y+ V+N +G V++ V D+ PP+
Sbjct: 6687 ADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRK 6746
Query: 1271 ASDIR---------------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
D+ S+ +++ W+ DG V + S N C
Sbjct: 6747 LKDVNAILGASVVLECRVSGSAPISVGWF---QDGNEIVSGPKCQSSFSEN-------VC 6796
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKP--EEPKDEVEV 1368
+ N+ L P + A NV G+ E S + TV E P E+ D VEV
Sbjct: 6797 ---TLNLSLLEPSDTGIYTCVAANVAGSDEC---SAVLTVQEPPSFEQTPDSVEV 6845
Score = 71.6 bits (174), Expect = 6e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 27164 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 27222
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 27223 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 27276
Score = 71.2 bits (173), Expect = 8e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1255
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 13924 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 13972
Query: 1256 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 13973 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 14032
Query: 1312 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1368
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 14033 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 14092
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1526 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1584
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1585 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1643
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1644 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1703
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1704 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1763
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1764 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1805
Score = 70.9 bits (172), Expect = 1e-11
Identities = 60/249 (24%), Positives = 94/249 (37%), Gaps = 46/249 (18%)
Query: 1029 PAFKQKLQD-VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
P+F ++L + V EG L+ +V+ P T+ W N ++ T ++ + + +
Sbjct: 8249 PSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQ 8308
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
+ KA D GLY C NDAG A C+ + +
Sbjct: 8309 VRKAGMNDAGLYTCKVSNDAGSALCTSSIVI----------------------------- 8339
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
K P K PP Q V GE V+L V G++PI W+K +
Sbjct: 8340 ------------KEPKK---PPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGR 8384
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD-PPA 1266
+I+ S+ + + L + + G Y N GS + +T+ DKP PA
Sbjct: 8385 EIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAPA 8444
Query: 1267 GTPCASDIR 1275
A D R
Sbjct: 8445 TKKAAVDGR 8453
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 27632
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y + N C++ V P + T P K + P
Sbjct: 27633 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 27663
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1214
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 27664 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 27705
Query: 1215 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1268
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 27706 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 27762
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1326
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 27763 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 27822
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1386
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 27823 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 27874
Query: 1387 TEQKVSD------FYDIEERLGSGKF 1406
+ D Y IE+R G+ ++
Sbjct: 27875 WNPPLRDGGSKIVGYSIEKRQGNERW 27900
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 13697 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 13756
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y A N G+A +V V D P PP +D T +
Sbjct: 13757 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 13798
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
PP+ +I + +++ E W K ++++
Sbjct: 13799 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 13842
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1270
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 13843 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 13889
Query: 1271 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1327
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 13890 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 13949
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 13950 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 13984
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1746
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.7 bits (169), Expect = 2e-11
Identities = 51/223 (22%), Positives = 89/223 (39%), Gaps = 38/223 (17%)
Query: 26 SMPLTEAPAFI--LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
++ + E P+F+ + P L + G +A+ +++G P QVTW +N + ++ +
Sbjct: 3730 TVTVREPPSFVKKVDPSYLMLP-GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYF 3788
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ L I V ED G Y+CEA N G+ + E+ ++
Sbjct: 3789 -VNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------------------ 3829
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PP F L + G C+++G +++W K ++
Sbjct: 3830 ----------------PPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS 3873
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
S + + + + LEI N DVG Y C+V N GK A
Sbjct: 3874 SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMA 3916
Score = 69.3 bits (168), Expect = 3e-11
Identities = 61/269 (22%), Positives = 98/269 (36%), Gaps = 61/269 (22%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+F+Q V V G L + PP + W + L + +S E + + +
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELEL 6893
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ P + G Y C+ NDAG A C+ + V +
Sbjct: 6894 FEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP--------------------------- 6926
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
AT K+ A D V G + L TGT PI+ +W+K
Sbjct: 6927 --ATFVKRLA------------------DFSVETGSPIVLEATYTGTPPISVSWIKDEYL 6966
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP------ 1262
I +SE + +E + L IL + E Y+ L+EN+ G + ++V++ P
Sbjct: 6967 ISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPL 7026
Query: 1263 -------DPPAGTPCASDIRSSSLTLSWY 1284
PA C D + + +SWY
Sbjct: 7027 EHVEAVIGEPATLQCKVD-GTPEIRISWY 7054
Score = 69.3 bits (168), Expect = 3e-11
Identities = 153/729 (20%), Positives = 270/729 (37%), Gaps = 101/729 (13%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 497
L V E+ F+ LKD V E + +C + T + W I+ +
Sbjct: 11479 LTVKEIELDFAVPLKDVTVPERRQARFECVL--TREANVIWSKGPDIIKSSDKFDIIADG 11536
Query: 498 ELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
+ HI D+ +D G YT E + S +VT K
Sbjct: 11537 KKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGIRLK------------------- 11575
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F+ L D V +G T ++S + V+W N ++ S G H L ++
Sbjct: 11576 -FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMK 11633
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
EV +D + E+ + A L V E P+F K TA + + C
Sbjct: 11634 EVTLDDISQIKAQV----KELSSTAQLKVLE----ADPYFTVKLHDKTAVEKDEITLKCE 11685
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ D V W +DG+ + + + + L +KK G+Y C
Sbjct: 11686 VSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYV---------C 11733
Query: 735 SCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG---ADGGGSDRYGSLRPGWPARGQG 790
C N + A L + +P ++ G + D +G W +GQ
Sbjct: 11734 DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ----WKLKGQP 11789
Query: 791 WLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLS 842
D E + K + T + + +A + L ++L + LS
Sbjct: 11790 LTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKEL--PLIFITPLS 11847
Query: 843 EDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQV--DFRSVLAKKGTSKTPVPE 900
D+K ++ F + R+ PKT R + Q++ D R L K GT + V +
Sbjct: 11848 --DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQEITGDDRFELIKDGTKHSMVIK 11899
Query: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
A F + + +G E + K + K ++ + + V +
Sbjct: 11900 SAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS 11953
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
+K N + T + + + + + S + ++L D + + + G + K
Sbjct: 11954 HDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDLSIDDTSQIRVEA--MGMSSEAK 12010
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
+ +G P F KLQD E +++LQC++S A + W +GK +K +K ++ +
Sbjct: 12011 LTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVIKAD 12068
Query: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
G + ++KAL D G Y C D G + S ++ ++D E+K RP S
Sbjct: 12069 GKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR---------EIKLVRPLHS 12115
Query: 1141 LPPVLGTES 1149
+ V+ TE+
Sbjct: 12116 V-EVMETET 12123
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1148 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1202
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 23410 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 23469
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
K K I K +N E G + + + EN +G +A N
Sbjct: 23470 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 23518
Query: 1263 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1318
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 23519 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 23578
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1369
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 23579 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 23638
Query: 1370 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1426
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 23639 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 23698
Query: 1427 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1485
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 23699 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 23758
Query: 1486 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1529
E + E + +++ EG EY+ + IM VNK G
Sbjct: 23759 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 23800
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1288
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 26050 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 26109
Query: 1289 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 26110 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 26169
Query: 1348 QESELTTVGEKPEEPKDEVE 1367
S+ E+ EEP +++
Sbjct: 26170 DSSDPQIAKEREEEPLFDID 26189
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 18201 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 18260
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1144
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 18261 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 18312
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
TV P P+ + I++ E +++ W
Sbjct: 18313 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 18345
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1261
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 18346 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 18393
Query: 1262 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 18394 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 18449
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 18450 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 18496
Score = 68.6 bits (166), Expect = 5e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 25454
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++A ED G Y+ N AG + V D P PP
Sbjct: 25455 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 25496
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+ + PP+ QI + ++K + + TW +
Sbjct: 25497 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 25540
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1264
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 25541 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 25588
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1317
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 25589 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 25643
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1377
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 25644 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 25702
Query: 1378 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1406
+ + + K++ + L G++
Sbjct: 25703 LKWSKPHYDGGAKITGYIVERRELPDGRW 25731
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 33127 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 33186
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1125
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 33187 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 33246
Query: 1126 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1166
++++ +M + + ++S + + + + K A + +
Sbjct: 33247 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 33306
Query: 1167 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
+PP+I P D + G+ + + TG TW
Sbjct: 33307 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 33366
Query: 1207 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 33367 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 68.2 bits (165), Expect = 7e-11
Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 45/235 (19%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
AP K+K++ + VA G C++ S P W G+ + + + + S+
Sbjct: 3455 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 3514
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
I + D G Y C A N+ G C+ +TV +A
Sbjct: 3515 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEA-------------------------- 3548
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
PP + P+ G++ + VTGT I W K
Sbjct: 3549 -------------------YPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGA 3589
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ S + ++ ++EN L + + G Y+ NK G+ Q L ++DKP
Sbjct: 3590 ALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKP 3644
Score = 68.2 bits (165), Expect = 7e-11
Identities = 48/162 (29%), Positives = 76/162 (46%), Gaps = 12/162 (7%)
Query: 1624 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1678
KW K G + A I +++A + S +G T ++ E S + + L+
Sbjct: 4049 KWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLD 4108
Query: 1679 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1738
+ P+F+K +R+++ V R DCKI G V WFKD + I S ++I
Sbjct: 4109 R------DIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIA 4162
Query: 1739 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ E G SL I V +D +TC+A NS+G + LIV+
Sbjct: 4163 FVE-GTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQ 4203
Score = 68.2 bits (165), Expect = 7e-11
Identities = 60/273 (21%), Positives = 101/273 (36%), Gaps = 63/273 (23%)
Query: 1028 APA-FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1086
APA F ++L D + +GK L+L+ + PP ++ W NG + ++ ++ +
Sbjct: 7866 APAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAIL 7925
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1146
I + ED G Y C +N +G+ CS Q+ + +
Sbjct: 7926 EIPSSTVEDAGQYNCYIENASGKDSCSAQILILE-------------------------- 7959
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
PP ++ E KV G+S L ++ GT I +W K
Sbjct: 7960 ---------------------PPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGD 7998
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
+++ + K+ N + L G Y EN +G A LTV ++ PP+
Sbjct: 7999 TKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPS 8058
Query: 1267 ------------GTPCASDIR---SSSLTLSWY 1284
G P D S +++SWY
Sbjct: 8059 FSRQLRDVQETVGLPVVFDCAISGSEPISVSWY 8091
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1668 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1085
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3298
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3299 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3341
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP II +D G+ +V+GT + +W
Sbjct: 3342 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3380
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
K+I+ S ++ E+ +L I A E G YT + N +G + NL++
Sbjct: 3381 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3433
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 17517 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 17576
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 17624
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P P I E Q R + +G V+
Sbjct: 17625 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 17655
Query: 1215 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1267
+GS T L GC + + ENK+G + V K P P G
Sbjct: 17656 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 17708
Query: 1268 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1321
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 17709 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 17763
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
V L + Y+FRV A N+ G S+PS S+
Sbjct: 17764 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 17793
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 19307 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 19366
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1155
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 19367 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 19426
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
K P A +V+ T PIT ++ K I+ E+
Sbjct: 19427 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 19459
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1271
+ + ENK G + K DPP P
Sbjct: 19460 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 19496
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 19497 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 19556
Query: 1330 EYKFRVRAINVYGTSEPSQESE 1351
EY+FRV AIN G +PS S+
Sbjct: 19557 EYEFRVTAINKAGPGKPSDASK 19578
Score = 66.6 bits (161), Expect = 2e-10
Identities = 56/235 (23%), Positives = 93/235 (39%), Gaps = 48/235 (20%)
Query: 1029 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
P F +K V V G+ +CQ++ P + W L+G + + +S L +
Sbjct: 4861 PQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQ 4920
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
I A E+ G Y C A+NDAG A CS ++ V + P T E+K
Sbjct: 4921 ISGARVENSGTYVCEARNDAGTASCSIELKVKEPP----TFIRELK-------------- 4962
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
P +++++ + VEL +VTGT P TW+K +
Sbjct: 4963 --------------------PVEVVKYSD---------VELECEVTGTPPFEVTWLKNNR 4993
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+I+ S+ + + + L I G Y +V N+ GS + + + P
Sbjct: 4994 EIRSSKKYTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPP 5048
Score = 66.6 bits (161), Expect = 2e-10
Identities = 60/261 (22%), Positives = 98/261 (37%), Gaps = 47/261 (18%)
Query: 1005 DVNCKRGHAGTTDNEK---RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII 1061
+ CK ++ T + K R + + P+F ++L+D+ G + L C+++ P +
Sbjct: 6148 EYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVC 6207
Query: 1062 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
W +G L+ + + S ++ ++ I + G Y C A N G A S ++T
Sbjct: 6208 WYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLT---- 6263
Query: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
+R PK S P P V
Sbjct: 6264 ------------AREPKKS----------------------------PFFDIKPVSIDVI 6283
Query: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1241
AGES + VTG QP+ TW K K+I+ + + N L IL + G YT
Sbjct: 6284 AGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTC 6343
Query: 1242 LVENKLGSRQAQVNLTVVDKP 1262
N +G L+V + P
Sbjct: 6344 QATNDVGKDMCSAQLSVKEPP 6364
Score = 66.6 bits (161), Expect = 2e-10
Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 43/237 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F +L V G+ +C V+ P + W + + +++ +S + +++
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTV 8212
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
K D G Y C A N+ G+ C+ Q+ + + +PP
Sbjct: 8213 LKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKER------------------LIPPSFTKR 8254
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
TV++ G S +L G+V G+QPIT W K +
Sbjct: 8255 LSETVEETE-------------------------GNSFKLEGRVAGSQPITVAWYKNNIE 8289
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
IQ + + ++ N L + A G YT V N GS ++ + + PP
Sbjct: 8290 IQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPP 8346
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1014 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1065
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 26164 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 26223
Query: 1066 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 26224 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 26279
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1185
PP T D T + A + + PE+
Sbjct: 26280 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 26304
Query: 1186 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1243
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 26305 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 26353
Query: 1244 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 26354 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 26412
Query: 1301 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1360
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 26413 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 26472
Query: 1361 EPKDEVE 1367
P+ +++
Sbjct: 26473 PPEIDMK 26479
Score = 66.2 bits (160), Expect = 3e-10
Identities = 60/253 (23%), Positives = 98/253 (38%), Gaps = 44/253 (17%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P F+ P++ + + + V G + W ++ + + SG +
Sbjct: 4762 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDT 4821
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
T SL + A D G Y C+ +N G L F K+
Sbjct: 4822 ST-SLELFAAKATDSGTYICQLSNDVGTATSKATL-----FVKE---------------- 4859
Query: 147 PAVETRPSIWGECPPKFATKLGRVVV-KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
PP+F K V+V + GQ F C+ITG P+ +V+W +
Sbjct: 4860 -------------PPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQ 4906
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
+ +S +G+ +I G ++ G Y C N +G AS S EL ++ +F+RE K
Sbjct: 4907 KHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVK----EPPTFIRELK 4962
Query: 266 ATN----SDVRKE 274
SDV E
Sbjct: 4963 PVEVVKYSDVELE 4975
Score = 65.9 bits (159), Expect = 3e-10
Identities = 38/113 (33%), Positives = 58/113 (51%), Gaps = 15/113 (13%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P+F + ++ V G +A F+C + G +V W KD + IR +QI Y E+ + L
Sbjct: 8153 PFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLEN-SAHLT 8211
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAEL--------------IVETMEEGEG 1787
+ V D +YTC AVN +G+ +CTA+L + ET+EE EG
Sbjct: 8212 VLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEG 8264
Score = 65.9 bits (159), Expect = 3e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 15172
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y A N G + +V V D P P L PV+ T +
Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 15218
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 15219 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 15254
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1273
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 15255 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 15305
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1331
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 15306 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 15365
Query: 1332 KFRVRAINVYGTSEPS 1347
+FRV+A+N G SEPS
Sbjct: 15366 EFRVKAVNEIGESEPS 15381
Score = 65.9 bits (159), Expect = 3e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 21535
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A N G A+ V V D P P V S+ V P
Sbjct: 21536 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 21582
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I+Q E ++ W ++Q ++
Sbjct: 21583 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 21613
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1277
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 21614 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 21669
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 21670 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 21729
Query: 1336 RAINVYGTSEPSQES 1350
A N G S PS S
Sbjct: 21730 MAENAAGISAPSPTS 21744
Score = 65.9 bits (159), Expect = 3e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 22016 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 22074
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 22075 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 22134
Query: 1349 ES 1350
S
Sbjct: 22135 LS 22136
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 29342 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 29400
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 29401 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 29454
Score = 65.5 bits (158), Expect = 5e-10
Identities = 54/234 (23%), Positives = 84/234 (35%), Gaps = 44/234 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F +KL+DVH G + +C+++ P + W +G LK + S ++ ++ I
Sbjct: 7116 PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQI 7175
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ G Y C A N G A S ++ + +
Sbjct: 7176 LQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE-------------------------- 7209
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+PP P + GES VTGT PI TW K ++
Sbjct: 7210 ------------------VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNRE 7251
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
I+ + K+ EN + LT+L + G YT N G L V + P
Sbjct: 7252 IRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305
Score = 65.5 bits (158), Expect = 5e-10
Identities = 84/382 (21%), Positives = 154/382 (40%), Gaps = 28/382 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 24034 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 24091
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 24092 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 24143
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDSPRTAPQTPVLQKTSSSI--- 345
AK KN +R + AN + + S K+E+ + + + +
Sbjct: 24144 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 24202
Query: 346 TLQAARVQPEPRAPGLGVLSPSG--------EERKRPAPPRPATFPTRQPGLGSQ--DVV 395
T+ A + P PG L+ E+ + R + G++ +V
Sbjct: 24203 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 24262
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
+++ + G +F K +++ K + V + + PS +
Sbjct: 24263 AESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS 24322
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALPEDHGTY 512
+ G+D ++ V G P P I+W+ +G+P+ Q R E A LHI++ +D G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382
Query: 513 TCLAENALGQVSCSAWVTVHEK 534
T A N+ G + + V V EK
Sbjct: 24383 TVTATNSAGTATENLSVIVLEK 24404
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 30926 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 30985
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 30986 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 31027
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 31028 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 31076
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 31077 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 31130
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 31131 SDVSRDSVNLTWTEPASD 31148
Score = 65.1 bits (157), Expect = 6e-10
Identities = 53/220 (24%), Positives = 83/220 (37%), Gaps = 32/220 (14%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ E P F+ + + G +A + ++ G PE V+W++ + + +
Sbjct: 7957 ILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFR-NNV 8015
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
+LV + V D G+Y C+A N G + LTV+
Sbjct: 8016 ATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQ---------------------- 8053
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
+ PP F+ +L V G F C I+G V+W K PL+ S V
Sbjct: 8054 ---------KLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQ 8104
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
S + L I ++ G Y+C N G AS SA L
Sbjct: 8105 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 24312 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 24371
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y A N AG A + V V + P PPV
Sbjct: 24372 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 24413
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D + PP QI + +++ T TW
Sbjct: 24414 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 24457
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1262
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 24458 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 24505
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1320
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 24506 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 24564
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 24565 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 24606
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 32538 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 32596
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 32597 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 32654
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 32655 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 32715 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 32772
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 32773 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 32832
Query: 275 VTNVISK 281
+ V K
Sbjct: 32833 ESTVTRK 32839
Score = 64.3 bits (155), Expect = 1e-09
Identities = 69/307 (22%), Positives = 116/307 (37%), Gaps = 64/307 (20%)
Query: 985 KPDENLKS------ASKEELKKDVKND--VNCKRGHA-GTTDNEKR--SESQGTAPAFKQ 1033
+ DENL++ A+ + L+ D+ + +C + GT + R + +P F
Sbjct: 6216 RDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDI 6275
Query: 1034 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1093
K + V G+ +C V+ P I W+ + K ++ ++ G+ + I K
Sbjct: 6276 KPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGK 6335
Query: 1094 EDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATV 1153
D G Y C A ND G+ CS Q++V +
Sbjct: 6336 GDSGQYTCQATNDVGKDMCSAQLSVKE--------------------------------- 6362
Query: 1154 KKKPAPKTPPKAAMPPQIIQFPEDQKV-RAGESVELFGKVTGTQPITCTWMKFRKQIQES 1212
PP+ ++ E KV + GES++L K++G+ I +W + ++ ES
Sbjct: 6363 --------------PPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHES 6408
Query: 1213 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP-----DPPAG 1267
+ + + LTI A E G Y N +G LTV P P G
Sbjct: 6409 WKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVG 6468
Query: 1268 TPCASDI 1274
SD+
Sbjct: 6469 ALKGSDV 6475
Score = 64.3 bits (155), Expect = 1e-09
Identities = 31/114 (27%), Positives = 63/114 (55%), Gaps = 7/114 (6%)
Query: 1667 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
E+ +D+ +A + + PYF + + +E V G A CK++G P+ + W+K+
Sbjct: 7004 EAGQDICEALVSVLEP------PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEH 7057
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+R + +++ + ++ SL+I+ V D +Y+CKA NS+G +A L+++
Sbjct: 7058 TKLRSAPAYKMQF-KNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 17920 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 17979
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 17980 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 18038
Query: 1300 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1356
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 18039 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 18097
Query: 1357 -EKPEEPKD 1364
++P EP++
Sbjct: 18098 IDRPGEPEN 18106
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1146 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1200
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 20161 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 20209
Query: 1201 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++F R + K K+T L E+ + ++ N G + +
Sbjct: 20210 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 20267
Query: 1259 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 20268 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 20327
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1362
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 20328 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376
Score = 63.9 bits (154), Expect = 1e-09
Identities = 67/331 (20%), Positives = 125/331 (37%), Gaps = 69/331 (20%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
+P F ++ + + V + ++L +V+ PP I W + L++ + + L S+
Sbjct: 4392 SPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQ 4451
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
I K + D G Y+C N+ G + CS +VT+ +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARVTLRE--------------------------- 4484
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
PP I+ E G + + G+ PIT TW+K
Sbjct: 4485 --------------------PPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSD 4524
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP----- 1262
+I E +++++ N + L + +H G Y +N G ++ L+V +
Sbjct: 4525 EITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEE 4584
Query: 1263 ----DPPAGTPCASDIRSS---SLTLSWY--GSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
D G P ++ S +T W+ G GS Y I + D+ + K ++
Sbjct: 4585 AVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS---KYKISVTDTVS-ILKIIS 4640
Query: 1314 TCRSTS----FNVQDLLPDHEYKFRVRAINV 1340
T + S F VQ+ + K R+ +++
Sbjct: 4641 TEKKDSGEYTFEVQNDVGRSSCKARINVLDL 4671
Score = 63.9 bits (154), Expect = 1e-09
Identities = 43/163 (26%), Positives = 73/163 (44%), Gaps = 14/163 (8%)
Query: 1624 KWQKTGNAVRA-----IGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLE 1678
KW K G + I +++++ +S K +G T E + DV ++ +
Sbjct: 4611 KWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT-------FEVQNDVGRSSCK 4663
Query: 1679 A-VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
A + + P F+K ++ ++ ++GS +C + G + WFKDDQ I S ++
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ D L IS + G D YTC A N G C+ L V+
Sbjct: 4724 SF-HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 63.9 bits (154), Expect = 1e-09
Identities = 53/230 (23%), Positives = 85/230 (36%), Gaps = 44/230 (19%)
Query: 1033 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1092
+K + V V E + L+C V+ P + W +GK + +++ +S E ++ S I+ +
Sbjct: 5145 EKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVM 5204
Query: 1093 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1152
+D G Y +ND G + C + V D ++PP T
Sbjct: 5205 KQDSGQYTFKVENDFGSSSCDAYLRVLD------------------QNIPP------SFT 5240
Query: 1153 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1212
K K G S+ + KV+G+ PI+ W K K+I S
Sbjct: 5241 KKLTKMDKV--------------------LGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280
Query: 1213 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
++ E L + E YT V N G LTV + P
Sbjct: 5281 AKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPP 5330
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 23098 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 23156
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 23157 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 23214
Score = 63.5 bits (153), Expect = 2e-09
Identities = 87/403 (21%), Positives = 150/403 (37%), Gaps = 89/403 (22%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +LV HI+ L+V PA+ +++ +KEG T + P
Sbjct: 8725 GNYRLVCGPHIASAKLTVIE-----------PAWERHLQDVTLKEGQTCTMTCQF-SVPN 8772
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
+ W RNG+ + GR + + L I V ED+G+YTC+ + + + EL
Sbjct: 8773 VKSEWFRNGRILKPQGRHKTEVEHK-VHKLTIADVRAEDQGQYTCKYED----LETSAEL 8827
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
+E P +F ++ +VV E Q F
Sbjct: 8828 RIEAE---------------------------------PIQFTKRIQNIVVSEHQSATFE 8854
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV-VNGSG 240
C+++ VTW KG L S + + + IH V DD GVY+ + + G
Sbjct: 8855 CEVS-FDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 8913
Query: 241 KASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSP 300
+A +AEL + T +++ E+ +S++ ++
Sbjct: 8914 EARSTAELYL----------------TTKEIKLELKPPDIPDSRVPIPTMPIRA------ 8951
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
PP PP L + ++ P ++ T ++ A +V +P+
Sbjct: 8952 ----VPPEEIPPVVAPPIPLLLPTPEEK---KPPPKRIEVTKKAVKKDAKKVVAKPKE-- 9002
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRI 403
++P E K+P PP P + P + DV SKA +I
Sbjct: 9003 ---MTPREEIVKKPPPP-TTLIPAKAPEI--IDVSSKAEEVKI 9039
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1202
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 22329 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 22387
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+K K K E G + + + G +G V P
Sbjct: 22388 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 22438
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1320
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 22439 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 22498
Query: 1321 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1363
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 22499 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 22542
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 26946
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G A + +V + D P P + T T+ +P P
Sbjct: 26947 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 26993
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I++ E +V W SEH++ E
Sbjct: 26994 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 27023
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 27024 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 27080
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 27081 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140
Query: 1336 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1370
A+N G S+ SE + P P ++ ++D
Sbjct: 27141 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 27177
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2078 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2137
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2138 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2172
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1314
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 15704 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 15763
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 15764 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 15818
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1314
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 17110 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 17168
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1363
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 17169 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 17217
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 994
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 18788 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 18838
Query: 995 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1035
+EE D + + + + G + +K E++G A +Q L
Sbjct: 18839 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 18898
Query: 1036 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 18958
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1146
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 18959 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 19003
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
++DA P + + I+ E V G+ V VT T +
Sbjct: 19004 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 19054
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
K I E++ +EN G L K+ AQ V +P
Sbjct: 19055 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 19099
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1319
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 19100 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 19150
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 19151 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 19200
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 31638
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 31639 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 31692
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 31693 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 31752
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 31753 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1017 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1074
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1696 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1750
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1134
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1751 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1806
Query: 1135 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1194
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866
Query: 1195 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1254
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1925
Query: 1255 NLTVVDKPD 1263
L + + D
Sbjct: 1926 KLEIQQRED 1934
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/246 (23%), Positives = 97/246 (39%), Gaps = 46/246 (18%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E P+FI + G TA F+ ++G VTW ++ IT D IR T
Sbjct: 4482 LREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITE------DDNIRMT 4535
Query: 89 F-----SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
F SL + + + GKY C+A N +G ++ + L+V+
Sbjct: 4536 FENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK------------------- 4576
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PA T ++ + V +G K +G + W K L
Sbjct: 4577 --EPATITEEAV-------------SIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTL 4621
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
++ +S + + +L+I + D G YT V N G++S A +++ L SF ++
Sbjct: 4622 GSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKARINVLDL-IIPPSFTKK 4680
Query: 264 TKATNS 269
K +S
Sbjct: 4681 LKKMDS 4686
Score = 62.8 bits (151), Expect = 3e-09
Identities = 51/225 (22%), Positives = 83/225 (36%), Gaps = 35/225 (15%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P FI + + + + + + E V G P +VTW +N + I S ++ L +
Sbjct: 4949 LKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRV- 5007
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
F+L I D G+Y C +N G+ + + ++
Sbjct: 5008 SVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE--------------------- 5046
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
PP F K+ F + G P +TWLK + L
Sbjct: 5047 -------------PPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 5093
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
V +S + + L+I V+ G YTC N SG A L +Q
Sbjct: 5094 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 62.8 bits (151), Expect = 3e-09
Identities = 57/244 (23%), Positives = 86/244 (35%), Gaps = 35/244 (14%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
V ++ L E P F+ +L + G A+ + + G V W + + + +
Sbjct: 5601 VCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRIT 5660
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ +L + GKY C+ N G R+ L V
Sbjct: 5661 FVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV-------------------- 5700
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP 203
PAV K G + V G+ CK+ G P+ V W K L
Sbjct: 5701 -LEPAV-------------IVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTS 5746
Query: 204 SARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRE 263
S + S N + L I V + D G YT V N GK+S +A + + + SF R
Sbjct: 5747 SQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSD-RAVPPSFTRR 5805
Query: 264 TKAT 267
K T
Sbjct: 5806 LKNT 5809
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1317
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 22837 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 22895
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 22896 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 22946
Score = 62.4 bits (150), Expect = 4e-09
Identities = 53/248 (21%), Positives = 95/248 (38%), Gaps = 47/248 (18%)
Query: 1030 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1089
AF ++L D V GK ++L+ + P ++ W +G + T++ + C + I
Sbjct: 5987 AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEIL 6046
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
+ D G Y C +N+AG+ C V+ + PP TE
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGALVSTLE---------------------PPYFVTEL 6085
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
+ P +AA+ G+SV L +V GT IT +W K ++
Sbjct: 6086 E-----------PLEAAV---------------GDSVSLQCQVAGTPEITVSWYKGDTKL 6119
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
+ + + + N + L G YT EN +G+ ++ + ++ PP+
Sbjct: 6120 RPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFAR 6179
Query: 1270 CASDIRSS 1277
DI +
Sbjct: 6180 QLKDIEQT 6187
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 500
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 30532 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 30591
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 559
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 30592 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 30638
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 30639 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 30694
Query: 620 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 30695 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 30743
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1049
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1050 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1081
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1260
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 16256 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1314
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 16316 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 16374
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 16375 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 16422
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 18021
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
+ P D G IT +++RK Q+ +
Sbjct: 18022 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 18052
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1271
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 18053 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 18110
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 18111 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 18169
Query: 1330 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 18170 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 18208
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1074
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1125
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1169
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1170 QI 1171
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1456 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1515
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
II D ++T A N G ++ + L VE +E
Sbjct: 1516 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1551
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/433 (21%), Positives = 165/433 (38%), Gaps = 47/433 (10%)
Query: 314 PQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKR 373
P+P E ++ + R P+ + + +I L A +P+P A + P E
Sbjct: 10983 PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT 11042
Query: 374 PAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFES-----KPQSQEVKEN 428
P P T P ++ +AA + P++G E+ +P S K
Sbjct: 11043 PIAA-PVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP 11101
Query: 429 QTVKFRCEGLAVMEVAPSFSSVLKDCAVIE----GQDFVLQCSVRGTPVPRIT-WLLNGQ 483
F + + V F +KD + E G + +C V +P IT W+ +G
Sbjct: 11102 DEAPFTYQ---LKAVPLKFVKEIKDIILTESEFVGSSAIFECLV--SPSTAITTWMKDGS 11156
Query: 484 PIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKS 540
I+ + R + +LHI D D G YTC+ + + +A + V E
Sbjct: 11157 NIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEE------- 11209
Query: 541 EYLLPVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
LPV F++ L ++ V+ G + ++ ++ N +V+W +G + E
Sbjct: 11210 ---LPVR--------FVKTLEEEVTVVKGQPLYLSCEL--NKERDVVWRKDGKIVVEKPG 11256
Query: 600 FHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP 658
G +L I + D GTYT N+ + V V+ D W +
Sbjct: 11257 RIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRD----WLVKPI 11312
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGHFEVLQNEDVFTLVLKKVQP 717
R + + +C IA D P + W + + + E+L++ + L +K P
Sbjct: 11313 RDQHVKPKGTAIFACDIAKDT-PNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMP 11371
Query: 718 WHAGQYEILLKNR 730
+Y + ++ +
Sbjct: 11372 EDIAEYAVEIEGK 11384
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1239 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1295
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 21331 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 21389
Query: 1296 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1352
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 21390 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 21449
Query: 1353 TTVGEKPEEPKDEVEVSDDD 1372
T + E PK +V+V D
Sbjct: 21450 ITCRDDVEAPKIKVDVKFKD 21469
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 22207
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 22208 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 22249
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D T PP K G S+ + V T TW
Sbjct: 22250 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 22291
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1262
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 22292 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 22338
Query: 1263 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1318
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 22339 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 22398
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 22399 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 22457
Query: 1379 DYRTVTINTEQKVSDFYDIEERLGSGKF 1406
++ T + K++ + ++ L G++
Sbjct: 22458 QWKKPTYDGGSKITGYIVEKKELPEGRW 22485
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 22547 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 22603
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 22646
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1206
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 22647 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 22696
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1261
KV G++ T + ++ NK G + + VV K
Sbjct: 22697 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 22736
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1319
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 22737 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 22795
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 22796 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 22826
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W+K K + K + G + + + G +G V
Sbjct: 24551 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 24601
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1319
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 24602 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 24661
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 24662 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 24710
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 28145 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 28200
Query: 1312 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1366
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 28201 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 28260
Query: 1367 EVSDDDEKEPEVDY 1380
+V+D + +++
Sbjct: 28261 KVTDTSKTTVSLEW 28274
Score = 61.2 bits (147), Expect = 9e-09
Identities = 27/81 (33%), Positives = 51/81 (62%), Gaps = 1/81 (1%)
Query: 1700 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1759
++ G +AR CK++G P +V WFK+++ + ES ++ Y + L I+DV +D
Sbjct: 3749 MLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRM-YFVNSEAILDITDVKVEDSGS 3807
Query: 1760 YTCKAVNSLGEATCTAELIVE 1780
Y+C+AVN +G +C+ E++++
Sbjct: 3808 YSCEAVNDVGSDSCSTEIVIK 3828
Score = 61.2 bits (147), Expect = 9e-09
Identities = 49/235 (20%), Positives = 90/235 (38%), Gaps = 48/235 (20%)
Query: 1029 PAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
P F +KL+ + + G L+C+++ P ++W N L + ++ S+ +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQ 5482
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
+ ED G + C A+N AG CS +V V + P SS PP++ T
Sbjct: 5483 MNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVF--------------SSFPPIVET 5528
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
+A V L +++GT P W K ++
Sbjct: 5529 LKNA---------------------------------EVSLECELSGTPPFEVVWYKDKR 5555
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
Q++ S+ K+ + + + IL G Y +N++GS + + + P
Sbjct: 5556 QLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPP 5610
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 25002 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 25058
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 25059 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 25110
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 29748 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 29807
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1154
Y KN G + +V + D P P+ E DAT +
Sbjct: 29808 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 29852
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 29853 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 29902
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 29903 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 29943
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1327
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 29944 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 29998
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1363
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 29999 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 30040
Score = 60.8 bits (146), Expect = 1e-08
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3338 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3396
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3397 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3447
Score = 60.5 bits (145), Expect = 1e-08
Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 41/238 (17%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F Q L V V+EG+ + L C V P I W G+ +K + S + +
Sbjct: 8346 PVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLEL 8405
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
D G Y C A N AG S+ TK
Sbjct: 8406 RDVAKADSGDYVCKASNVAG---------------SDTTK-------------------- 8430
Query: 1149 SDATVKKKPA--PKTPPKAAMPPQIIQFPEDQKVRAGE--SVELFGKVTGTQPITCTWMK 1204
S T+K KPA P T KAA+ ++ E Q +R E + KV G W K
Sbjct: 8431 SKVTIKDKPAVAPATK-KAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTK 8489
Query: 1205 FR-KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
+ +Q+ + + + + +KL I + G Y + N+ G ++ VNL V ++
Sbjct: 8490 GKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDER 8547
Score = 60.5 bits (145), Expect = 1e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 19589 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 19647
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 19648 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 19676
Score = 60.5 bits (145), Expect = 1e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1256 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 28540 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 28598
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 28645
Score = 60.5 bits (145), Expect = 1e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 32847 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 32905
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 32906 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1315
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 21753 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 21811
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 21812 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 21843
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W K K + MKV + G Y + EN G + + V
Sbjct: 25633 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 25681
Query: 1262 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1317
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 25741
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 25742 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 25797
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/318 (23%), Positives = 124/318 (38%), Gaps = 51/318 (16%)
Query: 430 TVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 489
T K EG V F L+D V E L+C V + W N ++
Sbjct: 2257 TAKLIVEGAVV-----EFVKELQDIEVPESYSGELECIVSPENIEG-KWYHNDVELKSNG 2310
Query: 490 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 546
T G L ++D ED G Y+ + + KK++ K +
Sbjct: 2311 KYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---------------KKTTCKLKM---- 2351
Query: 547 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG 606
KP LQGLSD KV +G V + V+VS E +W+ +G E+Q S+ H
Sbjct: 2352 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV-EGVWMKDGQEVQPSDRVHIVIDK 2407
Query: 607 TQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
H L I+++ ED G Y+ +++G V +V I+ + V
Sbjct: 2408 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV------------ITPLKDVN 2455
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
G ++ C ++ +V W + + + K + + LV+ + G
Sbjct: 2456 VIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGP 2514
Query: 723 YEILLKNRVGECSCQVSL 740
Y++++ RV E +C +S+
Sbjct: 2515 YKLIV-GRV-ETNCNLSV 2530
Score = 59.7 bits (143), Expect = 2e-08
Identities = 52/241 (21%), Positives = 87/241 (36%), Gaps = 54/241 (22%)
Query: 1015 TTDNEKRSESQGTA------PAFKQKLQDVHVA-EGKKLLLQCQVSSDPPATIIWTLNGK 1067
T NE S S P+F +K+ ++ G+ L C++ P + W N K
Sbjct: 3717 TASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNK 3776
Query: 1068 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1127
L + + + S + I ED G Y C A ND G CS ++ + +
Sbjct: 3777 ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKE------- 3829
Query: 1128 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1187
PP I+ E + G +
Sbjct: 3830 ----------------------------------------PPSFIKTLEPADIVRGTNAL 3849
Query: 1188 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1247
L +V+GT P +W K +KQI+ S+ ++ + ++ L I + G Y +V N++
Sbjct: 3850 LQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEV 3909
Query: 1248 G 1248
G
Sbjct: 3910 G 3910
Score = 59.3 bits (142), Expect = 3e-08
Identities = 73/351 (20%), Positives = 128/351 (36%), Gaps = 64/351 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+F +K++ G Q + P T+ W + + I ++ E ++ S+ +
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYL 4545
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA----------------PASENTK---A 1129
+ G Y C AKNDAG CS ++V + PA+ K
Sbjct: 4546 SGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQGDPATLQVKFSGT 4605
Query: 1130 PEMKSRRPKSSLPPVLGTESDATV------------KKKPAP-----------KTPPKAA 1166
E+ ++ K LG++ +V +KK + ++ KA
Sbjct: 4606 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVGRSSCKAR 4665
Query: 1167 M-------PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1219
+ PP + + G ++L V G+ PI+ W K ++I SE K
Sbjct: 4666 INVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSF 4725
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP---DPPAGTPCASDIR- 1275
+N + L I G YT NK G Q +LTV + P + P + R
Sbjct: 4726 HDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRV 4785
Query: 1276 --------SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1318
++ +T+ W+ + + S + +W T EL ++T
Sbjct: 4786 QLKALVGGTAPMTIKWFKDNKELHSGA---ARSVWKDDTSTSLELFAAKAT 4833
Score = 59.3 bits (142), Expect = 3e-08
Identities = 28/92 (30%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
PYF K + ++V G +A C++ G P+ V W+K D +R + +++ + + +L+
Sbjct: 7961 PYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHF-RNNVATLV 8019
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ V +D +Y CKA NS+GE + + L V+
Sbjct: 8020 FNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 58.9 bits (141), Expect = 4e-08
Identities = 42/128 (32%), Positives = 59/128 (46%), Gaps = 2/128 (1%)
Query: 1652 SSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCK 1711
++ G +S N LE+ E + +E E + P + I LEV G A+F C+
Sbjct: 3420 NAVGQVSSTANLS-LEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCE 3478
Query: 1712 IEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1771
I+ P+ WFK + I ES I + + SL I D +YTCKA N G
Sbjct: 3479 IQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSV 3537
Query: 1772 TCTAELIV 1779
+CTA L V
Sbjct: 3538 SCTATLTV 3545
Score = 58.9 bits (141), Expect = 4e-08
Identities = 51/237 (21%), Positives = 86/237 (36%), Gaps = 44/237 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F +L+ + A G + LQCQV+ P T+ W L+ T ++ ++
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVF 6138
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
K D G Y C A+N +GT
Sbjct: 6139 NKVNINDSGEYTCKAENS--------------------------------------IGTA 6160
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
S TV + + +PP + +D + G V L ++ G+ PI W +
Sbjct: 6161 SSKTVFR------IQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVL 6214
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+++ E+++ +N + L IL H G Y+ N LG+ + LT + P
Sbjct: 6215 LRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSP 6271
Score = 58.9 bits (141), Expect = 4e-08
Identities = 41/157 (26%), Positives = 68/157 (43%), Gaps = 4/157 (2%)
Query: 1624 KWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEE 1683
KW K G + + + ++ + +SG K +P S E + V + A +
Sbjct: 7618 KWFKDGKELTSDNKYK-ISFFNKVSGLKIINVAP-SDSGVYSFEVQNPVGKDSCTASLQV 7675
Query: 1684 KPH-VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
V P F++ +++ + GS+ +CK+ G P V WF + I R +Q D
Sbjct: 7676 SDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTL-TD 7734
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
C+L ++ + D YTC A N G C+A L V
Sbjct: 7735 NTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTV 7771
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1062 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 14130 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 14173
Query: 1121 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1180
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 14174 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 14224
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
R G W+K K + +V + G+++ + G
Sbjct: 14225 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 14265
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 14266 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 14319
Query: 1298 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 14320 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 14379
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1387
+ +P ++E D E E V +R V + T
Sbjct: 14380 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 14417
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 23637 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 23696
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
A N AG V V D P P V G S+ K
Sbjct: 23697 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 23739
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1219
+PP I + +++ E+ L V ++ +T
Sbjct: 23740 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 23775
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1274
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 23776 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 23830
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1332
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 23831 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 23890
Query: 1333 FRVRAINVYGTSEPS 1347
FRV A N G EPS
Sbjct: 23891 FRVSAENAAGVGEPS 23905
Score = 58.5 bits (140), Expect = 6e-08
Identities = 60/273 (21%), Positives = 100/273 (36%), Gaps = 48/273 (17%)
Query: 992 SASKEELKKDVKNDVN--CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQ 1049
+AS E ++ D+ + N C+ ++ + + + P+F K V G + L+
Sbjct: 4167 TASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLK 4226
Query: 1050 CQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
P TI W K L + +++E S+ + D G Y C N AG
Sbjct: 4227 STFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGG 4286
Query: 1110 AECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1169
ECS + V + AT +K P
Sbjct: 4287 VECSANLFV-----------------------------KEPATFVEKLEP---------- 4307
Query: 1170 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1229
Q ++ G++ +L KVTGT PI TW ++I+ES ++ E+ + L +
Sbjct: 4308 -------SQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360
Query: 1230 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
E G Y +N+ GS + V + P
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESP 4393
Score = 58.5 bits (140), Expect = 6e-08
Identities = 63/295 (21%), Positives = 120/295 (40%), Gaps = 37/295 (12%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEA 494
L V+E P F+ L+D +E + +LQC + P + W +G+ I+ +++ +
Sbjct: 12011 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADG 12069
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
L ++ AL D G YTC G S + + +++
Sbjct: 12070 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDREIK----------------- 12108
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
++ L ++VM+ ++S + W G + ++ D ++ G HSL +
Sbjct: 12109 -LVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIKEEGKIHSLVLH 12166
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ TG +A N V++ A L V+ G + + VT + G++ C
Sbjct: 12167 NCRLDQTGGVDFQAAN----VKSSAHLRVKPRVIG----LLRPLKDVTVTAGETATFDCE 12218
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
++ + P V W GK L + + V TL L+ V+ AG+ ++ K+
Sbjct: 12219 LSYEDIP-VEWYLKGKKL-EPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 12271
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1021 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1078
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 24699 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 24758
Query: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138
++ ++ + D G Y N G V V D P P
Sbjct: 24759 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 24805
Query: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1198
V G ++ P A + II+ E ++
Sbjct: 24806 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 24847
Query: 1199 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 24848 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 24893
Query: 1259 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1312
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 24894 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 24953
Query: 1313 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
T V L H Y+FRV A N G EPS+ S
Sbjct: 24954 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 24991
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 30531 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 30589
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 30590 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 30640
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 30641 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 30678
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 30679 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 30738
Query: 269 SDV 271
S V
Sbjct: 30739 SAV 30741
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1317
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 30823 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 30881
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 30882 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 30932
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1087
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1145
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 31914
Query: 1146 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1181
GTES +A V KPA T K +I + E++K+R
Sbjct: 31915 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 31969
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/230 (18%), Positives = 82/230 (35%), Gaps = 47/230 (20%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+F ++L++ G +L+C+V+ P ++ W + + + ++C++ +
Sbjct: 5800 PSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL 5859
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
D G Y CVA N AG EC +TV + P+
Sbjct: 5860 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPS------------------------- 5894
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
++ PE +V G++V + GT P W + ++
Sbjct: 5895 ----------------------FVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARE 5932
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ + + + + ++L + G YT +V N G L V
Sbjct: 5933 LVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFV 5982
Score = 58.2 bits (139), Expect = 7e-08
Identities = 55/284 (19%), Positives = 97/284 (34%), Gaps = 65/284 (22%)
Query: 988 ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLL 1047
+N+ + L + C + +D + + P+F ++ + + V GK +
Sbjct: 5852 DNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVT 5911
Query: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE---------DRGL 1098
+ PP + W + L +G C++ E + E G
Sbjct: 5912 FTSVIRGTPPFKVNWFRGARELV---------KGDRCNIYFEDTVAELELFNIDISQSGE 5962
Query: 1099 YKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPA 1158
Y CV N+AGQA C+ ++ V +
Sbjct: 5963 YTCVVSNNAGQASCTTRLFVKE-------------------------------------- 5984
Query: 1159 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
P ++ D V G+S+ L TGT PI+ TW K I SE +
Sbjct: 5985 ---------PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIV 6035
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+E L IL + + G Y+ +EN+ G ++ ++ P
Sbjct: 6036 TTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPP 6079
Score = 58.2 bits (139), Expect = 7e-08
Identities = 49/237 (20%), Positives = 84/237 (35%), Gaps = 44/237 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F + L+ V G+ LQC+V P I W L++ + + ++ S+ I
Sbjct: 7020 PYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVI 7079
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
K D G Y C A N G S + + K+R+
Sbjct: 7080 NKVDHSDVGEYSCKADNSVGAVASSAVLVI--------------KARK------------ 7113
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+PP + +D G V ++ G++P+ +W K
Sbjct: 7114 ------------------LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVL 7155
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+++ +++ N + L IL Q H G Y N LG+ + L + + PP
Sbjct: 7156 LKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPP 7212
Score = 57.8 bits (138), Expect = 9e-08
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1747
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+IS DD +YT N GE + +A L+ E
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1174
Score = 57.8 bits (138), Expect = 9e-08
Identities = 52/233 (22%), Positives = 90/233 (38%), Gaps = 50/233 (21%)
Query: 1033 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT---KFIILSQEGSLCSVSIE 1089
+K + V G+ L+C+V+ P ++ W +GK L ++ KF ++ SL +S+E
Sbjct: 5708 EKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVE 5767
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
+ +D G Y +N+ G++ C+ V V D
Sbjct: 5768 R---QDAGTYTFQVQNNVGKSSCTAVVDVSD----------------------------- 5795
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
A+PP + ++ G S L KV G+ PI+ W + +I
Sbjct: 5796 ---------------RAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKI 5840
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ S+N L + + G YT + N GS + + LTV + P
Sbjct: 5841 VSGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPP 5893
Score = 57.8 bits (138), Expect = 9e-08
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 24187 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 24246
Query: 1297 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 24247 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 24296
Score = 57.8 bits (138), Expect = 9e-08
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1670 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 31773 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 31832
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 31833 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 31892
Query: 1787 GEGEEEEE 1794
E + +EE
Sbjct: 31893 QEFKSKEE 31900
Score = 57.4 bits (137), Expect = 1e-07
Identities = 65/290 (22%), Positives = 112/290 (38%), Gaps = 42/290 (14%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAEL 499
A LK+ V E QD V + V + W+ NG ++ YA S + + L
Sbjct: 2706 AVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV-KGTIYSL 2764
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ D Y LG++ SA + V K +K +
Sbjct: 2765 RIKNCAIVDESVYGF----RLGRLGASARLHVETVKIIKKPK------------------ 2802
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
D+ ++ + V V VS + P V W H EI+ S+ H L +Q + P
Sbjct: 2803 --DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPS 2859
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679
D G YT G++ +A L V+ H I P + TAS C ++
Sbjct: 2860 DAGEYTA----VVGQLECKAKLFVETLHITKTMKNIEVPETKTAS------FECEVSHFN 2909
Query: 680 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
P++ WL++G + + + F+++ + L++ + +Y + N
Sbjct: 2910 VPSM-WLKNGVEI-EMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2957
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1747
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3239 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3296
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332
Score = 57.4 bits (137), Expect = 1e-07
Identities = 50/237 (21%), Positives = 87/237 (36%), Gaps = 47/237 (19%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F +K+ D+ G+ + LQ V P ++ W + ++ I +S + + I
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLII 3983
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
G Y C+A+N+AG Q +V + E
Sbjct: 3984 PDVQISFGGKYTCLAENEAGS-----QTSVGELIVKE----------------------- 4015
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
P +II+ E +V AG+ L V GT + W K +
Sbjct: 4016 -------------------PAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKDGRP 4056
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+ S+ ++ N ++L +A G YT + N++GS + TV+D+ P
Sbjct: 4057 LVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP 4113
Score = 57.4 bits (137), Expect = 1e-07
Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 2/93 (2%)
Query: 1689 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
P F K + +V +G + + +CKI G P+ +V WF++D + ES + + + + L
Sbjct: 6364 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF-INSVALL 6422
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I++ +D Y C+A N +G+A+C+ L V+
Sbjct: 6423 TINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 57.4 bits (137), Expect = 1e-07
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F K +E ++G+ +C+++G P V W+KD + +R + ++I E+ S+
Sbjct: 7399 PIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKI-MSENFLTSIH 7457
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I +V D +Y CKA N +G TC + ++
Sbjct: 7458 ILNVDAADIGEYQCKATNDVGSDTCVGSIALK 7489
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 23917 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 23975
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1373
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 24029
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1233 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1289
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 25263 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 25322
Query: 1290 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 25323 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381
Score = 57.0 bits (136), Expect = 2e-07
Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 8/160 (5%)
Query: 1624 KWQKTGNAVRAIGRLSSMAMISGLSG-RKSSTGSPTSPLNAEKLESEEDVSQ--AFLEAV 1680
KW K G + R SM+ + ++ R S S K+E++ S A+L +
Sbjct: 5173 KWLKDGKQI-VPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVL 5231
Query: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740
+ P P F+K + ++ V GS+ +CK+ G WFKD + I S +++
Sbjct: 5232 DQNIP---PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCH 5288
Query: 1741 EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
E + SL ++++ +D A YTCK N G+ C+ L V+
Sbjct: 5289 E-RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVK 5327
Score = 57.0 bits (136), Expect = 2e-07
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
PYF + LE G + C++ G P+ V W+K D +R + ++ Y + +L+
Sbjct: 6079 PYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYR-TYFTNNVATLV 6137
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEAT 1772
+ V +D +YTCKA NS+G A+
Sbjct: 6138 FNKVNINDSGEYTCKAENSIGTAS 6161
Score = 57.0 bits (136), Expect = 2e-07
Identities = 55/269 (20%), Positives = 96/269 (35%), Gaps = 62/269 (23%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F ++L D V G ++L+ + PP ++ W + + ++ ++ + I +
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1150
+ ED Y C+ +N+AGQ C V+V +
Sbjct: 6989 STIEDYAQYSCLIENEAGQDICEALVSVLE------------------------------ 7018
Query: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
PP I+ E + GE L KV GT I +W K +++
Sbjct: 7019 -----------------PPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7061
Query: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----- 1265
+ K++ N + L I G Y+ +N +G+ + L + + PP
Sbjct: 7062 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARK 7121
Query: 1266 -------AGTPCASDIR---SSSLTLSWY 1284
G P A + R S L +SWY
Sbjct: 7122 LKDVHETLGFPVAFECRINGSEPLQVSWY 7150
Score = 57.0 bits (136), Expect = 2e-07
Identities = 30/93 (32%), Positives = 53/93 (56%), Gaps = 2/93 (2%)
Query: 1689 PYFSKTIRDLEVV-EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
P F K + +V + R++CKI G P+ +V+W+KD+ I+ES F++ + D L
Sbjct: 7305 PRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF-VDSVAVL 7363
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ ++ +D YTC+A N+ G A+ + L V+
Sbjct: 7364 EMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVK 7396
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 16536 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 16593
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
+AKN+AG+ + + V V D P T P + S
Sbjct: 16594 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 16633
Query: 1160 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
++ F PED G PIT ++ +++ V
Sbjct: 16634 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 16667
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1272
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 16668 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 16726
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1330
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 16727 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 16786
Query: 1331 YKFRVRAINVYGTSEPS 1347
Y++RV A+N+ G +PS
Sbjct: 16787 YEYRVSAVNIVGQGKPS 16803
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A+N G+ + V D P PP + D
Sbjct: 21140 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 21170
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
+ + F D G V Q + TW++ + + +
Sbjct: 21171 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 21219
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 21220 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 21273
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 21274 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 21333
Query: 1336 RAINVYGTSEPSQESE 1351
A N+ G S+PS+ SE
Sbjct: 21334 IAENMAGKSKPSKPSE 21349
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 988 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1046
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 28606 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 28665
Query: 1047 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1106
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 28666 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 28725
Query: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
AG S V V P P + V +++ V PK
Sbjct: 28726 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 28772
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+ I++ E T W ++ ++ K+
Sbjct: 28773 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 28802
Query: 1227 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1282
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 28803 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 28860
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 28861 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 28920
Query: 1341 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
G S+ S+ S + + P + EV+D
Sbjct: 28921 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 28949
Score = 56.2 bits (134), Expect = 3e-07
Identities = 44/209 (21%), Positives = 76/209 (36%), Gaps = 34/209 (16%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV-IHAVHEEDRG 102
+ +G A + + G E W ++GQ +T G ++ + + T S++ I + ++D G
Sbjct: 4590 VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKIS--VTDTVSILKIISTEKKDSG 4647
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPK 162
+YT E N G + V PP
Sbjct: 4648 EYTFEVQNDVGRSSCKARINVLDLII-------------------------------PPS 4676
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
F KL ++ +G C + G + W K + + S + S + LEI
Sbjct: 4677 FTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQ 4736
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ D G YTC N +G S L+++
Sbjct: 4737 LEGTDSGTYTCSATNKAGHNQCSGHLTVK 4765
Score = 56.2 bits (134), Expect = 3e-07
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F++ + ++GS C+I G P EVVW KD + +R S+ F+I + + SL
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKIT-SKHFDTSLH 6516
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1777
I ++ D +Y CKA N +G TC+ +
Sbjct: 6517 ILNLEASDVGEYHCKATNEVGSDTCSCSV 6545
Score = 56.2 bits (134), Expect = 3e-07
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 1671 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
+VS + V E+K + P FS+ +RD++ G FDC I G V W+KD + ++
Sbjct: 8041 EVSASTFLTVQEQK--LPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLK 8098
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+S + Q + D +L I +Y+C A N +G A+ +A LI+
Sbjct: 8099 DSPNVQTSF-LDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLIL 8146
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1318
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 20672 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 20731
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 20732 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 20782
Query: 1379 DYRTVTINTEQKVSDFYDIEER 1400
RT+ + + F I+ R
Sbjct: 20783 -RRTLVVRAGLSIRIFVPIKGR 20803
Score = 56.2 bits (134), Expect = 3e-07
Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELH 500
P F +L + EGQ + V G P P + W +GQP+ + G+ LH
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 31854
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY 542
I+D LPED G Y A N G SC A + V E+ +K E+
Sbjct: 31855 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-ERLRYKKQEF 31895
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1657 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1714
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1807 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1866
Query: 1715 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1867 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1924
Query: 1775 AELIVETMEE 1784
+L ++ E+
Sbjct: 1925 VKLEIQQRED 1934
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 20934 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 20992
Query: 1291 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 20993 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 21051
Query: 1351 ELTTVGEKPEEPK 1363
V E+ P+
Sbjct: 21052 RPVIVKEQTMLPE 21064
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1266 A 1266
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 31/91 (34%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + L G AA+F C + G P E +W KD ++ S +++I D + L
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRIS-DAENKHILE 3609
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+S++ D Y+CKA N G C AELI+
Sbjct: 3610 LSNLTIQDRGVYSCKASNKFGADICQAELII 3640
Score = 55.5 bits (132), Expect = 5e-07
Identities = 67/319 (21%), Positives = 123/319 (38%), Gaps = 53/319 (16%)
Query: 1013 AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT 1072
+ + D R Q P+F +KL + G + ++C+VS P + W +GK + T+
Sbjct: 5221 SSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTS 5280
Query: 1073 -KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPE 1131
K+ ++ E S+ S+ + ED Y C N AG CS +TV + P S K P
Sbjct: 5281 AKYRLVCHERSV-SLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKE-PPSFLVK-PG 5337
Query: 1132 MKSRRPKSSL---------PP---------------------VLGTESDATVKKKPAPKT 1161
+ P S++ PP + G+ S + A KT
Sbjct: 5338 RQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKT 5397
Query: 1162 PPKAAM------------------PPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTW 1202
PP+ ++ E K V+AG+S L K+ G+ I W
Sbjct: 5398 GQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVW 5457
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ ++ S+ ++ ++ + + + E G + +N GS + V + P
Sbjct: 5458 FRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPP 5517
Query: 1263 DPPAGTPCASDIRSSSLTL 1281
+ P ++++ ++L
Sbjct: 5518 VFSSFPPIVETLKNAEVSL 5536
Score = 55.5 bits (132), Expect = 5e-07
Identities = 31/98 (31%), Positives = 51/98 (52%), Gaps = 3/98 (3%)
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
+P P+F ++V+ G +A F+C + G + W KD++ IR ++ I G
Sbjct: 6266 EPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC--VG 6323
Query: 1744 NC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
N L I V D +YTC+A N +G+ C+A+L V+
Sbjct: 6324 NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVK 6361
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1743
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 30924 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 30983
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
LII+ V DD Y +A N G + TA L VE
Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 33192
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I + D KYT KA N G+ + TA L+V + E
Sbjct: 33193 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 33228
Score = 55.1 bits (131), Expect = 6e-07
Identities = 41/159 (25%), Positives = 71/159 (44%), Gaps = 5/159 (3%)
Query: 1622 RRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVA 1681
R W GN + AI + ++ I GL+ + S G+ E+ D A
Sbjct: 4892 RVSWYLDGNEITAIQK-HGISFIDGLATFQIS-GARVENSGTYVCEARNDAGTA--SCSI 4947
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
E K P F + ++ +EVV+ S +C++ G P EV W K+++ IR S+ + + D
Sbjct: 4948 ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLT-DR 5006
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+L I+ D +Y C N G +C+ + ++
Sbjct: 5007 VSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALK 5045
Score = 55.1 bits (131), Expect = 6e-07
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P FS +E ++ + +C++ G P EVVW+KD + +R S+ ++I ++ + S+
Sbjct: 5517 PVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKI-ASKNFHTSIH 5575
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATC 1773
I +V D +Y CKA N +G TC
Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVGSDTC 5600
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1319
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 16422 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 16479
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 16480 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 16532
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1317
KP P P D + L W DGGS + Y +E W + R
Sbjct: 17802 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 17861
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 17862 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1199
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 18382 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 18439
Query: 1200 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
W+ K MKV+N +H + + EN++G + + V
Sbjct: 18440 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 18488
Query: 1260 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1309
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 18489 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 18548
Query: 1310 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 18549 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608
Query: 1367 EVS 1369
+ S
Sbjct: 18609 DAS 18611
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1330
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 29645 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 29704
Query: 1331 YKFRVRAINVYGTSEPSQESELTTV 1355
Y FR+RA N G SEP + TV
Sbjct: 29705 YLFRIRAQNEKGVSEPRETVTAVTV 29729
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 498
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 30927 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 30986
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 30987 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 31032
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 31033 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 31088
Query: 619 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 665
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 31089 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 31148
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA 691
G S + + + WLR G+A
Sbjct: 31149 GGSKITNYIVEKCATTAERWLRVGQA 31174
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1314
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 16012 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 16070
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1362
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 16071 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 16117
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1239 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 27829 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 27888
Query: 1297 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1350
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 27889 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944
Query: 1351 ELTTVGEKPEEP 1362
+ ++ P
Sbjct: 27945 GIIMTRDENVPP 27956
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1677 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1547 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1603
Query: 1737 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1604 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1659
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1089
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 16824 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 16879
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
KA D G Y V +N G + CQV V D P PPV
Sbjct: 16880 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 16921
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
D K P I +K G+ V + + + TC K K +
Sbjct: 16922 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 16977
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 16978 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 17022
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1326
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 17023 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 17077
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1379
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 17078 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 17130
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 22133 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 22175
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 22176 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 23301 GITVANVVGQKTASIEI 23317
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1745
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 31748
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 31749 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 53.9 bits (128), Expect = 1e-06
Identities = 51/230 (22%), Positives = 81/230 (35%), Gaps = 35/230 (15%)
Query: 22 SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL 81
+R++ + L P+F + + +G+ E V G + W ++ Q I++ ++
Sbjct: 4664 ARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKF 4723
Query: 82 DCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141
F L I + D G YTC ATN +G Q + LTV+
Sbjct: 4724 SFHDNTAF-LEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKE---------------- 4766
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
PP F K V + + G + W K N L
Sbjct: 4767 ------------------PPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL 4808
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
A SV + + LE+ D G Y C + N G A+ A L ++
Sbjct: 4809 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVK 4858
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 32841 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 32900
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1788
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 32901 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 32950
Score = 53.5 bits (127), Expect = 2e-06
Identities = 66/288 (22%), Positives = 114/288 (39%), Gaps = 41/288 (14%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDA 504
+ +K+ V E + +C V VP + WL NG I+ + + + +L I +
Sbjct: 2885 TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNT 2943
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG-LSDL 563
ED YT + N QVS + VT PI + L D+
Sbjct: 2944 STEDSAEYTFVCGN--DQVSATLTVT-----------------------PIMITSMLKDI 2978
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
+ +T V V+ WL NG EI+ ++ + HSL I+ V D
Sbjct: 2979 NAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAAD 3037
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
YT AG+ + A L V+ H F + + + + C ++ +P TV
Sbjct: 3038 YTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLEKKRAMFECEVS-EPDITV 3088
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 731
W++D + L + T ++ + + V L++ + AG+Y ++ V
Sbjct: 3089 QWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3135
Score = 53.5 bits (127), Expect = 2e-06
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
PYF+K + +EV++ ++ G P E+ WFKD+ +R R ++ + +D SL
Sbjct: 4393 PYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYK-TFIQDHLVSLQ 4451
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1777
I D +Y C+ N +G + C+A +
Sbjct: 4452 ILKFVAADAGEYQCRVTNEVGSSICSARV 4480
Score = 53.5 bits (127), Expect = 2e-06
Identities = 37/110 (33%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 1677 LEAVAEEKPHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHF 1735
LE AE + +P F+K I+++ V E +A F+C++ + D V W+K + ES+ +
Sbjct: 8821 LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEV-SFDDAIVTWYKGPTELTESQKY 8879
Query: 1736 QIDYDEDGNCS-LIISDVCGDDDAKYTCKA-VNSLGEATCTAELIVETME 1783
++ DG C + I +V DD+ Y+ A + GEA TAEL + T E
Sbjct: 8880 --NFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKE 8927
Score = 53.1 bits (126), Expect = 2e-06
Identities = 25/93 (26%), Positives = 54/93 (58%), Gaps = 2/93 (2%)
Query: 1689 PYFSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
P F K + ++V+ G ++R +CKI G P+ VVWF+++ + S +++ + D +
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTF-IDSVAVI 5481
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
++++ +D + C+A N G +C+ ++IV+
Sbjct: 5482 QMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514
Score = 53.1 bits (126), Expect = 2e-06
Identities = 95/436 (21%), Positives = 157/436 (36%), Gaps = 67/436 (15%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 23011
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
T + N SG + SA ++++ LD+ + N V + + +S + L+
Sbjct: 23012 TLTLENSSG--TKSAFVTVRVLDT-------PSPPVNLKVTEITKDSVSITWEPPLLDGG 23062
Query: 292 AKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
+K KN +R + +AA K++ ++ + V + I L A
Sbjct: 23063 SKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEG--CSYYFRVTAENEYGIGLPAQ 23120
Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
P A V P G+ + +P D SK + M+ +
Sbjct: 23121 TADPIKVAE---VPQPPGKITVDDVTRNSVSLSWTKP---EHDGGSKIIQYIVEMQAKHS 23174
Query: 411 SAFPKFESKPQSQEVKENQT----VKFRC-----------EGLAVMEVA------PSFSS 449
+ + Q V N T FR LAV VA P
Sbjct: 23175 EKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKP 23234
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALP 506
+V GQD ++ + G P P ITW +G P++ T + L I++
Sbjct: 23235 AFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHK 23294
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+D G Y N +GQ + S + +K P P P+ +S
Sbjct: 23295 DDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFDDVS----- 23336
Query: 567 DGSQVTMTVQVSGNPP 582
++ +S NPP
Sbjct: 23337 -----AESITLSWNPP 23347
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQ 28049
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 30533 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 30592
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+++ +D+ YTC A N +GE +++L+++
Sbjct: 30593 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 52.8 bits (125), Expect = 3e-06
Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
+G A + CK+ G P ++ WF +D+ I+ES ++ + E L ++DV +D +Y
Sbjct: 4313 KGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVE-STAVLRLTDVGIEDSGEYM 4371
Query: 1762 CKAVNSLGEATCTAELIVE 1780
C+A N G C++ +IV+
Sbjct: 4372 CEAQNEAGSDHCSSIVIVK 4390
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 4/113 (3%)
Query: 1668 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
S E S + VA ++P P F K I + V S+A F + G P + W KDDQ
Sbjct: 5030 SNEGGSCSCSTRVALKEP---PSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQ 5086
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ E + I + D +L I V +YTC+A N G C A L+V+
Sbjct: 5087 ILDEDDNVYISF-VDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138
Score = 52.8 bits (125), Expect = 3e-06
Identities = 50/235 (21%), Positives = 84/235 (35%), Gaps = 48/235 (20%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P F K V +A G+ +C V+ P I W + + ++ ++ + ++++
Sbjct: 7212 PFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTV 7271
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
K D G Y C A N AG+ CS Q+ V +
Sbjct: 7272 LKVGKGDAGQYTCYASNIAGKDSCSAQLGVQE---------------------------- 7303
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRK 1207
PP+ I+ E + V+ E K+ G+ I W K
Sbjct: 7304 -------------------PPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDET 7344
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+IQES ++ ++ + L + E G YT N GS + +L V + P
Sbjct: 7345 EIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPP 7399
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 665
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 29855
Query: 666 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 721
G + L + WL +++ + T F L + + + + G
Sbjct: 29856 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 29915
Query: 722 QYEILLKNRVGECSCQVSL 740
Y L++ V EC + +
Sbjct: 29916 SY---LQSEVIECRSSIRI 29931
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1081 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1140
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1141 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1177
Score = 52.4 bits (124), Expect = 4e-06
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F KT+ ++V G+ A C++ G E+ WFKD + IR S+ +++ + + L
Sbjct: 3831 PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRL-FSQKSLVCLE 3889
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTA 1775
I D +Y C N +G+ C A
Sbjct: 3890 IFSFNSADVGEYECVVANEVGKCGCMA 3916
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1661 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1720
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 22121 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 22179
Query: 1721 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 22180 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 22237
Score = 52.4 bits (124), Expect = 4e-06
Identities = 94/441 (21%), Positives = 159/441 (36%), Gaps = 63/441 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V ++ G R ++GRP P +TW K + L A + +E + +++ VN+ D G
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAG 29513
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVRKE---------VTNVI 279
YT N SGK S + + + S V+E + + E V N I
Sbjct: 29514 KYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYI 29573
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSP------------PWAANSQPQPPRESKLESCKD 327
++ + + CS S P +P S +
Sbjct: 29574 VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 29633
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
P + V+ T S++TL +P G L+ E + R T +P
Sbjct: 29634 VPLVPAKLEVVDVTKSTVTL----AWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 29689
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSF 447
+ V S EG++ + +++ E +E T + L V+
Sbjct: 29690 TVLEHTVTSL-------NEGEQYLFRIRAQNEKGVSEPRETVTA-VTVQDLRVLPTIDLS 29741
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCE--AGVAELHIQDA 504
+ K V G+ L + G P P +W G ++ + R T E VA+L I++
Sbjct: 29742 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 29801
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
D G YT +N G S + V + +K P PT PI +
Sbjct: 29802 TIRDTGEYTLELKNVTGTTSETIKVIILDK-------------PGPPTGPI------KID 29842
Query: 565 VMDGSQVTMTVQVSGNPPPEV 585
+D + +T++ + PPE+
Sbjct: 29843 EIDATSITISWE-----PPEL 29858
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1211
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 30315 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 30374
Query: 1212 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1263
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 30375 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 30432
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1321
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 30433 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 30491
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1369
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 30492 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 30543
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 31578 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 31637
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 31638 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 31672
Score = 52.0 bits (123), Expect = 5e-06
Identities = 54/233 (23%), Positives = 82/233 (35%), Gaps = 48/233 (20%)
Query: 1031 FKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1089
F +KL+ + + G L C+V+ PP I W N + +K + +S S + +
Sbjct: 4301 FVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT 4360
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
ED G Y C A+N+AG CS V V ++P
Sbjct: 4361 DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPY-------------------------- 4394
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
T + KP +V V L +V GT P TW K +
Sbjct: 4395 -FTKEFKPI--------------------EVLKEYDVMLLAEVAGTPPFEITWFKDNTIL 4433
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ K ++ L IL G Y V N++GS +T+ + P
Sbjct: 4434 RSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPP 4486
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 17283
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 17284 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 17331
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P G SV V + W ++ H
Sbjct: 17332 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 17369
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1272
+E L +AA EN+ G + DP P G P
Sbjct: 17370 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 17417
Query: 1273 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 17418 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 17477
Query: 1331 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
Y+FRV+A N+ G P + EK P E++V
Sbjct: 17478 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 17514
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 27968 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 28026
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070
Score = 51.6 bits (122), Expect = 7e-06
Identities = 51/244 (20%), Positives = 83/244 (34%), Gaps = 55/244 (22%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILSQEGSLCSV 1086
AP F + L++V L C+++ P + W +GK + + ++ I EG+ S+
Sbjct: 4112 APFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGT-ASL 4170
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1146
I + D G + C A N G + S + V +
Sbjct: 4171 EIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQE-------------------------- 4204
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
PP + P + V G +V L G+ P+T W K
Sbjct: 4205 ---------------------PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN 4243
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL------TVVD 1260
K++ + S L + + G YT V N G + NL T V+
Sbjct: 4244 KELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVE 4303
Query: 1261 KPDP 1264
K +P
Sbjct: 4304 KLEP 4307
Score = 51.6 bits (122), Expect = 7e-06
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
+ ++V E +C + G P+ +V W KD + I SR+F + + E+ S I V
Sbjct: 5148 KSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSF-ENNVASFRIQSVMKQ 5206
Query: 1756 DDAKYTCKAVNSLGEATCTAELIV 1779
D +YT K N G ++C A L V
Sbjct: 5207 DSGQYTFKVENDFGSSSCDAYLRV 5230
Score = 51.6 bits (122), Expect = 7e-06
Identities = 90/418 (21%), Positives = 158/418 (37%), Gaps = 69/418 (16%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 20843
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 20844 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 20901
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 20902 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 20961
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T
Sbjct: 20962 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV 21017
Query: 386 QPGLGSQDVVSKAANR-----RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAV 440
+ G + VV ++ + P+ ES+P + + QT+ L
Sbjct: 21018 K---GLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRP---VIVKEQTM------LPE 21064
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVA 497
+++ + ++ A G + ++ V G P P +TW Q + Q A
Sbjct: 21065 LDLRGIYQKLVIAKA---GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 21121
Query: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
L+I + + D G Y A N +G+V + VH+ P PT PI
Sbjct: 21122 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD-------------IPGPPTGPI 21166
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1258
W K K + + H KV G + + EN G +
Sbjct: 26716 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 26764
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 26765 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 26823
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1348
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 26824 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 26856
Score = 51.2 bits (121), Expect = 9e-06
Identities = 55/198 (27%), Positives = 76/198 (38%), Gaps = 39/198 (19%)
Query: 452 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPED 508
KD +E + SV VP + W +P R E V +L +Q+ P D
Sbjct: 2802 KDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSD 2860
Query: 509 HGTYTCLAENALGQVSCSAWV---TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 565
G YT + +GQ+ C A + T+H K+ + E P TA
Sbjct: 2861 AGEYTAV----VGQLECKAKLFVETLHITKTMKNIE-----VPETKTA------------ 2899
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 625
+ +VS P + WL NG EI+ SE F +G H L I ED+ YT
Sbjct: 2900 ------SFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYT 2952
Query: 626 CEAWNSAGEVRTQAVLTV 643
N + A LTV
Sbjct: 2953 FVCGND----QVSATLTV 2966
Score = 51.2 bits (121), Expect = 9e-06
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
V P F + ++D+ + G++ +C++ G V WF+D I Q + E+ C+
Sbjct: 6739 VPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSEN-VCT 6797
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L +S + D YTC A N G C+A L V+
Sbjct: 6798 LNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQ 6831
Score = 51.2 bits (121), Expect = 9e-06
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1747
P F K + D+ V G + IEG VVWFKD + +RES + I Y E+ +L
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-IATL 7550
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
S V + KYTC+ N G C A L V
Sbjct: 7551 QFSRVEPANAGKYTCQIKNDAGMQECFATLSV 7582
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1316
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 15000 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 15057
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 15058 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 15109
Score = 50.8 bits (120), Expect = 1e-05
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
V P F++ +++ V G++ +CK+ G V WF + I +Q + D C+
Sbjct: 5798 VPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTF-SDNVCT 5856
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L ++ + D YTC A N G C A L V+
Sbjct: 5857 LQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQ 5890
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1056 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1114
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 27299 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 27358
Query: 1115 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1169
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 27359 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 27410
Query: 1170 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1229
TW + + ++ SE
Sbjct: 27411 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 27436
Query: 1230 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1287
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 27437 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 27487
Query: 1288 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 27488 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 27547
Query: 1348 QESELTTVGEKPEEPKDEVEVSD 1370
+ TV E P EV++SD
Sbjct: 27548 TIGPI-TVKELIITP--EVDLSD 27567
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1274
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 28208 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 28265
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1332
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 28266 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 28325
Query: 1333 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
FRV AIN G + + + ++ P+ +++ +
Sbjct: 28326 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 28362
Score = 50.4 bits (119), Expect = 2e-05
Identities = 31/92 (33%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F K + DL + G + G V W K + IRE ++ + +G LI
Sbjct: 3924 PTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFS-NGVAVLI 3982
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I DV KYTC A N G T ELIV+
Sbjct: 3983 IPDVQISFGGKYTCLAENEAGSQTSVGELIVK 4014
Score = 50.4 bits (119), Expect = 2e-05
Identities = 31/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 1673 SQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRES 1732
S A L A + P P+F++ ++D+ G F+C+I G +V W+KD +++
Sbjct: 7103 SSAVLVIKARKLP---PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDD 7159
Query: 1733 RHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+ Q + + +L I +Y C A N LG A+ +A+LI+ E
Sbjct: 7160 ANLQTSFVHN-VATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Score = 50.1 bits (118), Expect = 2e-05
Identities = 55/281 (19%), Positives = 99/281 (35%), Gaps = 50/281 (17%)
Query: 972 AKPAETLKPMGNAKPD--ENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAP 1029
AK ++P GN K EN + + ++ K C + D+ P
Sbjct: 7246 AKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPP 7305
Query: 1030 AFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
F +KL+ + + + +C++ P ++W + ++ + +S S+ + +
Sbjct: 7306 RFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM 7365
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
ED G Y C A N AG A S + V + PP+
Sbjct: 7366 HNLSVEDSGDYTCEAHNAAGSASSSTSLKVKE---------------------PPIF--- 7401
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+KKP P K G V L ++ GT P +W K +++
Sbjct: 7402 -----RKKPHPIETLK------------------GADVHLECELQGTPPFHVSWYKDKRE 7438
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGS 1249
++ + K+ + + + IL G Y N +GS
Sbjct: 7439 LRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 7479
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 30530 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 30588
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
TL + + G Y + N VGE L+LQ
Sbjct: 30589 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 30623
Score = 49.7 bits (117), Expect = 3e-05
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 1/94 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
V P+F +++ G + F C + G ++ W KD++ IR ++++ E+ +
Sbjct: 7210 VPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVEN-TAT 7268
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L + V D +YTC A N G+ +C+A+L V+
Sbjct: 7269 LTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQ 7302
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 13732
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 13733 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 13792
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 13793 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 13827
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 15599 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 15657
Query: 1316 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1370
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 15658 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 15715
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 19767
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G+ E + V V D P PPV T + + P
Sbjct: 19768 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 19809
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P II + ++ + K T C+ FR V N E
Sbjct: 19810 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 19852
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1279
G + + EN+ G V P G +RS SS
Sbjct: 19853 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 19900
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1339
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 19901 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 19959
Query: 1340 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
G P SE+T V +D+V D D K
Sbjct: 19960 ENGEGTP---SEITVVA------RDDVVAPDLDLK 19985
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 23296
Query: 720 AGQYEILLKNRVGECSCQVSLM 741
GQY I + N VG+ + + ++
Sbjct: 23297 GGQYGITVANVVGQKTASIEIV 23318
Score = 49.3 bits (116), Expect = 3e-05
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F K I + G A F ++G V W KD I E + ++ + E+ SL
Sbjct: 4486 PSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTF-ENNVASLY 4544
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+S + D KY C+A N G C+A L V+
Sbjct: 4545 LSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 19364
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 19365 DYTITAENSSGSKSATIKLKV 19385
Score = 48.9 bits (115), Expect = 4e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1062 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472
Query: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
P PP S+ + +K TPP I + +++
Sbjct: 20473 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 20512
Query: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1241
E+ L W + IQ H+ + + G++ + H G
Sbjct: 20513 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 20553
Query: 1242 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 20554 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 20608
Query: 1300 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1357
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 20609 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 20668
Query: 1358 K--PEEPKDEVEVSDDDEK 1374
P P V+D +K
Sbjct: 20669 AAYPPGPPSNPHVTDTTKK 20687
Score = 48.5 bits (114), Expect = 6e-05
Identities = 92/445 (20%), Positives = 156/445 (35%), Gaps = 76/445 (17%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 17287
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANR----SFVRET------KATNSDVRKEVTNVISK 281
+ V N +G ++S ++ + R S +R+ K D +TN + +
Sbjct: 17288 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 17347
Query: 282 ESKLDS-----LEAAAKSKN--CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQ 334
+ S L A +K K+ G + ++ Q R +E+ K P
Sbjct: 17348 RRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPL 17407
Query: 335 TPV--------LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
P + + ++L + + +P G L EE
Sbjct: 17408 HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEE---------------- 17451
Query: 387 PGLGSQDVV--SKAANRRIPMEGQRDSAFPKFESKPQS--QEVKENQTVKFRCEGLAVME 442
G+QD + N + G + +F K ++ + T+ C+ V
Sbjct: 17452 ---GTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPP 17508
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAEL 499
+++ V G +RG PVP W +G I ++ + + L
Sbjct: 17509 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVL 17568
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ L D G Y NA G + + +TV + P PT PI
Sbjct: 17569 TIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD-------------VPGPPTGPI---- 17611
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPE 584
++D + MT +S PP +
Sbjct: 17612 ----NILDVTPEHMT--ISWQPPKD 17630
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 19267 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 19325
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 19326 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 19382
Query: 121 LTV 123
L V
Sbjct: 19383 LKV 19385
Score = 48.5 bits (114), Expect = 6e-05
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+ K G+ + GRP P VTW K L AR S+ + +L I V ++D G
Sbjct: 27281 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 27340
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDS 255
Y + NG G+ S+ +S++ LD+
Sbjct: 27341 KYILTIENGVGEPK-SSTVSVKVLDT 27365
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1256 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 30024 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 30081
Query: 1314 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 30082 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 30139
Score = 48.1 bits (113), Expect = 7e-05
Identities = 88/408 (21%), Positives = 158/408 (38%), Gaps = 69/408 (16%)
Query: 179 RFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
R I GRP P+V W + + + + S+ + +L + VN+ D G Y V N
Sbjct: 21879 RLFVPIKGRPAPEVKWARDHG--ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS 21936
Query: 239 SGKASMSAELSIQGLDSANRSF---VRETKATNS---------DVRKEVTNVISKESKLD 286
SG S SA ++++ LD+ V+E T+ D ++ N I ++ +
Sbjct: 21937 SG--SKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 21994
Query: 287 SLEAAAKSKNCSSP-------QRGGSPPWAANSQPQP----PRESKLESCKDSPRTAP-- 333
+ + NC Q G S + ++ + P E+ ES K S R P
Sbjct: 21995 RKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETA-ESVKASERPLPPG 22053
Query: 334 QTPVLQKTSSSITLQAARVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLG 390
+ ++ T +S++L + + + + LG + G ++ T T GL
Sbjct: 22054 KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATIT-GL- 22111
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSV 450
+ + + R+ + ++ + P+ S P + + + P+F +
Sbjct: 22112 ---IQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---------------LVIPPAFKLL 22153
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPE 507
V+ G+D + G P P +TW + P+ Q R E+ + L I+DA E
Sbjct: 22154 FNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 22213
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
D G Y N+ G+ + V V +K P PT P+
Sbjct: 22214 DVGHYVVKLTNSAGEAIETLNVIVLDK-------------PGPPTGPV 22248
Score = 48.1 bits (113), Expect = 7e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 25380 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 25422
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 25423 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 25480
Query: 249 SIQGLD 254
+I LD
Sbjct: 25481 TIIVLD 25486
Score = 48.1 bits (113), Expect = 7e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 25734 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 25789
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 25790 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 25849
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 25850 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1631 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1690
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 32495 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 32554
Query: 1691 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 32555 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 32613
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ IS V D+ Y+ NS G+ L ++
Sbjct: 32614 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651
Score = 47.8 bits (112), Expect = 1e-04
Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 14/132 (10%)
Query: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FE 603
++ S+ F + + ++++G VT ++SG P P++ W +G I+ E + F
Sbjct: 1283 ISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFL 1342
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS------- 656
Q G + SL I V PED G YT A N G L V+ P +I
Sbjct: 1343 QDG-RASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSR 1401
Query: 657 ----KPRSVTAS 664
PRSV+ S
Sbjct: 1402 IRSLSPRSVSRS 1413
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1739
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1696 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1754
Query: 1740 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+E G CSL D TC+A N G +A LIV+
Sbjct: 1755 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1795
Score = 47.8 bits (112), Expect = 1e-04
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F K LEV+ G F I G P +V WF+ + + + I Y ED L
Sbjct: 5893 PSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNI-YFEDTVAELE 5951
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ ++ +YTC N+ G+A+CT L V+
Sbjct: 5952 LFNIDISQSGEYTCVVSNNAGQASCTTRLFVK 5983
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1194 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1253
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 13515 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Query: 1254 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1307
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 13632
Query: 1308 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 13633 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 13692
Query: 1367 EV 1368
+V
Sbjct: 13693 DV 13694
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
VT +G +V + G P P++ WL+DG L K++ + E+ TL +K + H
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPL-KESEFVRFSKTENKITLSIKNAKKEHG 27631
Query: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRG 753
G+Y ++L N V C V + + + P+G
Sbjct: 27632 GKYTVILDNAV--CRIAVPITVITLGPPSKPKG 27662
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 506 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 561
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 27920 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 27969
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 27970 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 28026
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE 645
G YT EA N++G + + + VQ+
Sbjct: 28027 GVYTVEAKNASGSAKAEIKVKVQD 28050
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/95 (25%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
++ + P F++ ++D+E G C++ G +V W++D +R+ + Q + D
Sbjct: 6169 QERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSF-VD 6227
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1777
+L I +Y+C A N LG A+ +A L
Sbjct: 6228 NVATLKILQTDLSHSGQYSCSASNPLGTASSSARL 6262
Score = 47.4 bits (111), Expect = 1e-04
Identities = 117/571 (20%), Positives = 206/571 (36%), Gaps = 81/571 (14%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
E P F KL E C+++ V W K + PS + S+ ++
Sbjct: 11660 EADPYFTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI 11717
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS---ANRSFVRET-----KATNS 269
L+I + D G Y C KA+++ E + ++ FV ET + +
Sbjct: 11718 LKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEP 11777
Query: 270 DVR---KEVTNVISKESKLDSLEAAAKS----KNCSSPQRGGSPPWAANSQPQPPRESK- 321
DV K ++ + +E K NC G AAN++ + K
Sbjct: 11778 DVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKE 11837
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
L +P + V +K + + +R +P+ G +G++R
Sbjct: 11838 LPLIFITPLS--DVKVFEKDEAKFECEVSR-EPKTFRWLKGTQEITGDDR---------- 11884
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
F + G V+ AA D A FE++ ++ + K EG+ +
Sbjct: 11885 FELIKDGTKHSMVIKSAA--------FEDEAKYMFEAE------DKHTSGKLIIEGIRLK 11930
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 501
+ P LKD E + V + + R+ W N Q + RS + +
Sbjct: 11931 FLTP-----LKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSM 11976
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
QD T+ L+ + Q+ A SE L V P F L
Sbjct: 11977 QDEGKTHSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQ 12025
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D ++ +V + ++S P V W +G EI+ S++ + G + L +++ D
Sbjct: 12026 DYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDI 12084
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 681
G YTC+ G +T L +++ + + SV ++ I+ D
Sbjct: 12085 GQYTCD----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI- 12135
Query: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 712
+W G+AL + T E+ + + +LVL
Sbjct: 12136 HANWKLKGEALLQ-TPDCEIKEEGKIHSLVL 12165
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 13289 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 13347
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 13348 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 13402
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 563
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 19246 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 19305
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 620
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 19306 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 19362
Query: 621 TGTYTCEAWNSAG 633
+G YT A NS+G
Sbjct: 19363 SGDYTITAENSSG 19375
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 19993 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 20052
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 20053 YTITLKNVAGTKEGTISIKVVG 20074
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 24367
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 24368 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 27991
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 27992 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1318
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 29240 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 29298
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 29299 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 29342
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 29420 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 29477
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 29478 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Score = 47.0 bits (110), Expect = 2e-04
Identities = 104/465 (22%), Positives = 165/465 (35%), Gaps = 67/465 (14%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 15059 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 15113
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 15172
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 15173 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 15232
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 15233 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 15292
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 15293 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 15348
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
PT + + D + R+ + + P Q+ + T+K R
Sbjct: 15349 CPTTSFLVENLDE-HQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL------ 15401
Query: 442 EVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA------ 494
SV D ++ G+ + V G P+P+I W N I+ +
Sbjct: 15402 -------SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 15454
Query: 495 ---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
EL I A+ ED GTYT A N LG V + V V+++ S
Sbjct: 15455 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499
Score = 47.0 bits (110), Expect = 2e-04
Identities = 109/532 (20%), Positives = 188/532 (35%), Gaps = 89/532 (16%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 16828 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 16886
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V +G + D + +P +
Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM---VISWKPPL-----D 16938
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEI 220
+K+ ++++ ++G+ W+ + + + +VS + + I
Sbjct: 16939 DGGSKITNYIIEKKEVGKD------------VWMPVTSASAKTTCKVSKLLEGKDYIFRI 16986
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVR 272
H N G+ LV + SM A+ + D+ ++ V E ++ D
Sbjct: 16987 HAENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 17039
Query: 273 KEVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQP 316
K +TN I ++ + S A +K+ C R + P P
Sbjct: 17040 KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSP 17099
Query: 317 PRE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERK 372
P + +K K SP P+ S +T Q R + G V G+E
Sbjct: 17100 PSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW 17159
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKF---------ESKPQSQ 423
R A P + P + + G RD KF ES P
Sbjct: 17160 RRANHTPESCP----------------ETKYKVTGLRDGQTYKFRVLAVNAAGESDPA-- 17201
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
V E VK R E ++ A ++ ++ + G L ++G P P++TW +
Sbjct: 17202 HVPEPVLVKDRLEPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDR 17257
Query: 484 PIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
AR ++L I++A ED G Y+ EN G + S V V +K
Sbjct: 17258 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 17309
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1042 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1100
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 31581 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 31640
Query: 1101 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1159
C ND G+ ++ V + + RR T+KK K
Sbjct: 31641 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 31680
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1216
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 31681 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 31740
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1265
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 31741 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 31800
Query: 1266 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
G +IR S + TL W DG +IEI +
Sbjct: 31801 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 31851
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 31852 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 31908
Query: 1376 PEVDYRTVTI 1385
+ R I
Sbjct: 31909 IDKTLRMAEI 31918
Score = 46.6 bits (109), Expect = 2e-04
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 29/217 (13%)
Query: 1582 CYILNRLDCTQCLQH------PWLMKDTKNMEAKKLSKDRMKKYMARR-----KWQKTGN 1630
C N+ QC H P+ ++ ++ + ++ ++K + KW K
Sbjct: 4747 CSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNK 4806
Query: 1631 -----AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV--AEE 1683
A R++ + + + + + + +G+ L+ DV A +A +E
Sbjct: 4807 ELHSGAARSVWKDDTSTSLELFAAKATDSGTYICQLS-------NDVGTATSKATLFVKE 4859
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
P + K L + G + F+C+I G P V W+ D I + I + DG
Sbjct: 4860 PPQ---FIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISF-IDG 4915
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ IS ++ Y C+A N G A+C+ EL V+
Sbjct: 4916 LATFQISGARVENSGTYVCEARNDAGTASCSIELKVK 4952
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/95 (24%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Query: 1687 VKPYFSKTIRD-LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
+ P F+K + + +E EG++ + + ++ G V W+K++ I+ + + +I + ++
Sbjct: 8247 IPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITF-KNNTL 8305
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L + +D YTCK N G A CT+ ++++
Sbjct: 8306 VLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIK 8340
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 19987 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 20045
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 20046 QKSDAGKYTITLKNVAGTKEGTISIKVVG 20074
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1648 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1702
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 32681 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 32740
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 32741 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 32791
Query: 1763 K 1763
+
Sbjct: 32792 E 32792
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2451 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2510
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVD 1119
D G YK + G+ E +C ++V+
Sbjct: 2511 DEGPYKLI----VGRVETNCNLSVE 2531
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 2/92 (2%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1747
P F K + D + G A +EG+ VVW KD + IRES + +I + D +L
Sbjct: 6551 PRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISF-IDNIATL 6609
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ + KY C+ N G C+A L V
Sbjct: 6610 QLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641
Score = 45.8 bits (107), Expect = 4e-04
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 1679 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1738
++ ++P P F + + + V EG + C ++G + W K + I+ S
Sbjct: 8336 SIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFS 8395
Query: 1739 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ G L + DV D Y CKA N G T +++ ++
Sbjct: 8396 F-ASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 12372 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 12427
Query: 1745 CSLIISDVCGDDDAKYTCK 1763
L+I+ DD+A+Y+C+
Sbjct: 12428 RILVINKCLLDDEAEYSCE 12446
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 496
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 27957 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 28013
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
L ++DA + G YT A+NA G V V +
Sbjct: 28014 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 28050
Score = 45.8 bits (107), Expect = 4e-04
Identities = 88/439 (20%), Positives = 162/439 (36%), Gaps = 71/439 (16%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 32229 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 32288
Query: 311 --NSQPQPPRESKLESCKDSP---RTAPQTP--VLQKTSSSITLQAARVQPEPRAPGLGV 363
S+PQP E + ++ + SP RT P++P V + S S ++AR R +
Sbjct: 32289 LIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKA 32348
Query: 364 L---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
+ E + +P T + + + + R+P GQ +SKP
Sbjct: 32349 ALKTQKTSERKYEVLSQQPFTLDH------APRITLRMRSHRVPC-GQNTRFILNVQSKP 32401
Query: 421 QSQ--------EVKENQTVKF-RCEGLAVME--------------VAPSFSSVLKDCAVI 457
++ E++E+ + + G+ +E V ++ D A +
Sbjct: 32402 TAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 32461
Query: 458 E--GQDFVLQCSVR-GTPVPRITWLLNGQPIQYARST------CEAGVAELHIQDALPED 508
+ G D+ S R VPR + + YA S+ EA + ++ + E
Sbjct: 32462 DVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTET 32521
Query: 509 HGTYTCLAENALGQVSCSAWV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+ + +A ++ +A ++ EK ++RK + L A L + V
Sbjct: 32522 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVY 32573
Query: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 626
+G + G P P V WL G + S + + I V D G Y+
Sbjct: 32574 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 32633
Query: 627 EAWNSAGEVRTQAVLTVQE 645
NS G+ + LT+Q+
Sbjct: 32634 VVENSEGKQEAEFTLTIQK 32652
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3054 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3110
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ L+I D KYT A G TA+L VE
Sbjct: 3111 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3143
Score = 45.4 bits (106), Expect = 5e-04
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F +T +EV+ G + F I G P +V WFK + + I ED L
Sbjct: 6834 PSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISL-EDFVTELE 6892
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ +V + Y+C N G A+CT L V+
Sbjct: 6893 LFEVQPLESGDYSCLVTNDAGSASCTTHLFVK 6924
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 24323 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 24382
Query: 625 TCEAWNSAG-EVRTQAVLTVQEP 646
T A NSAG +V+ +++P
Sbjct: 24383 TVTATNSAGTATENLSVIVLEKP 24405
Score = 45.1 bits (105), Expect = 6e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1159 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1215
P PP A P++ + +R E G I W+ K R I +
Sbjct: 28837 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 28891
Query: 1216 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 28892 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 28950
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1329
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 28951 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 29010
Query: 1330 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 29011 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 29049
Score = 44.7 bits (104), Expect = 8e-04
Identities = 41/156 (26%), Positives = 64/156 (41%), Gaps = 6/156 (3%)
Query: 587 WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 646
W+ +G+ I+ES F G L I +V D G YTC E + A L V+E
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Query: 647 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 706
+ + VT GQ + +SC + + V W +DGK + + G
Sbjct: 11211 ---PVRFVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWRKDGKIVVEKPGRIVPGVIGL 11265
Query: 707 VFTLVLKKVQPWHAGQYEILLKNRVG-ECSCQVSLM 741
+ L + AG Y + ++N ECS V ++
Sbjct: 11266 MRALTINDADDTDAGTYTVTVENANNLECSSCVKVV 11301
Score = 44.7 bits (104), Expect = 8e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1317
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 19189 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 19248
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 19249 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 19300
Score = 44.7 bits (104), Expect = 8e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN-EDVFTLVLKKVQPWHAGQYE 724
G SV + I+G P PT+ W +D K L T ++N D+ ++++K ++G YE
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYE 26944
Query: 725 ILLKNRVGECSCQVSLML 742
+ L+N +G S + + +
Sbjct: 26945 LKLRNAMGSASATIRVQI 26962
Score = 44.3 bits (103), Expect = 0.001
Identities = 183/961 (19%), Positives = 338/961 (35%), Gaps = 154/961 (16%)
Query: 180 FSCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
F+C I + P + W KG +P +P+ + + L+I +D+ Y +
Sbjct: 11325 FACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 11383
Query: 238 GSGKASMS-AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
A ++ E ++ L + E ++ + D + I + KL E S
Sbjct: 11384 KRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD-IPGQWKLKG-ELLRPSPT 11441
Query: 297 CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP 356
C GG + L ++ TA T + ++ L+ V
Sbjct: 11442 CEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERR 11501
Query: 357 RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQR------D 410
+A VL+ P D++ + I +G++ D
Sbjct: 11502 QARFECVLTREANVIWSKGP----------------DIIKSSDKFDIIADGKKHILVIND 11545
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 470
S F + + EV+ +T L V + F S L+D V EG+ C +
Sbjct: 11546 SQFD--DEGVYTAEVEGKKT----SARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSH 11599
Query: 471 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
+ + W N + +R+ + + H + + E L +S
Sbjct: 11600 EKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQ 11646
Query: 531 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
V E S+ + + L P F L D ++ ++T+ +VS + P V W +
Sbjct: 11647 VKELSSTAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKD 11697
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN--SAGEVRTQA-VLTVQEPH 647
G EI S + + G + L I++ +D G Y C+ + V +A ++ V++P
Sbjct: 11698 GEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPL 11757
Query: 648 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNE 705
G + F+ + L + P VH W G+ L E++++
Sbjct: 11758 YGVEV-FVGETAHFEIELSE-------------PDVHGQWKLKGQPLTASPD-CEIIEDG 11802
Query: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR-------- 752
L+L Q G+ N + +V + S + +
Sbjct: 11803 KKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECE 11862
Query: 753 -GREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR 811
REP + L G + G DR+ ++ G + ++ ED + +
Sbjct: 11863 VSREPKTFRWLKGT---QEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED-- 11915
Query: 812 QHTE-----EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQR 862
+HT E IR + + L +D+ K+ V T LS D+++ + + N QR
Sbjct: 11916 KHTSGKLIIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQR 11967
Query: 863 QVKPKTVS-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKK 921
++VS ++E K HS + F+ L+ TS+ V + + K
Sbjct: 11968 LHTTRSVSMQDEGKTHS---ITFKD-LSIDDTSQIRVEAMG-------------MSSEAK 12010
Query: 922 LPAENGSS--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLK 979
L G + + + VE + + + S PV K + +KP NA
Sbjct: 12011 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------ 12064
Query: 980 PMGNAKPDENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
+K+ K+ LKK +K+D+ GT + + + + L
Sbjct: 12065 ----------IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLH 12114
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
V V E + + ++S D W L G+ L T + +EG + S+ + +
Sbjct: 12115 SVEVMETETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQT 12173
Query: 1097 G 1097
G
Sbjct: 12174 G 12174
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 17576
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 17577 DTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 532 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 22125 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 22184
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 649
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 22185 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 22244
Query: 650 TQP 652
T P
Sbjct: 22245 TGP 22247
Score = 44.3 bits (103), Expect = 0.001
Identities = 81/396 (20%), Positives = 141/396 (35%), Gaps = 56/396 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 25117 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 25174
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 25175 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 25232
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 25233 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 25292
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 25293 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 25352
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
GL G + V AA R P + E+K + + F +
Sbjct: 25353 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVI---ARDIEIKPSVELPFHTFNVKAR 25409
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAE 498
E + +G P + W +GQ ++ + V
Sbjct: 25410 E------------------QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS 25451
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
L I++A ED GTY N+ G ++ + V ++
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 25487
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 1/78 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
+ V G +CK+ G P+ V W+KD + + S+ + + + SL I V D
Sbjct: 5713 MTVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSF-YNKISSLRILSVERQDA 5771
Query: 1758 AKYTCKAVNSLGEATCTA 1775
YT + N++G+++CTA
Sbjct: 5772 GTYTFQVQNNVGKSSCTA 5789
Score = 43.9 bits (102), Expect = 0.001
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
++V G +C + G P+ WFKD + + ++I + + L I +V D
Sbjct: 7595 IKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVS-GLKIINVAPSDS 7653
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
Y+ + N +G+ +CTA L V
Sbjct: 7654 GVYSFEVQNPVGKDSCTASLQV 7675
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + ++V+ G+ F ++G P V WFK + + ED L
Sbjct: 7775 PSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSL-EDSVAELE 7833
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ DV +YTC N G+A+CT L ++
Sbjct: 7834 LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 18899 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 18957
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSG 18978
Score = 43.9 bits (102), Expect = 0.001
Identities = 112/518 (21%), Positives = 191/518 (36%), Gaps = 68/518 (13%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 29059 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 29116
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 29175
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 29176 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 29235
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 29236 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 29295
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 29296 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 29338
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 29339 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 29396
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
R F +G + AA + ++G + S+ + E + V+ R E
Sbjct: 29397 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSE----------YSESIAEIEPVE-RIE 29442
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 496
+ +E+A + K + G L SV G P P ITW G +
Sbjct: 29443 -IPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES 29498
Query: 497 AELHIQDALPE-DHGTYTCLAENALGQVSCSAWVTVHE 533
L I D + D G YT AEN G+ S + V V++
Sbjct: 29499 YSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD 29536
Score = 43.5 bits (101), Expect = 0.002
Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 1/92 (1%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
KP+F K + ++ +C+++ V W KD Q + + ++I + ED +L
Sbjct: 3643 KPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICF-EDKIATL 3701
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
I D Y C A N G ++C+A + V
Sbjct: 3702 EIPLAKLKDSGTYVCTASNEAGSSSCSATVTV 3733
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 16091 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 16144
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 16145 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 16200
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 16201 NLGTASKEMRLNVLG 16215
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2883 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2940
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2941 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2984
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1750
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 16126 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 16184
Query: 1751 DVCGDDDAKYTCKAVNSLGEAT 1772
D YT AVN+LG A+
Sbjct: 16185 QSRRSDTGLYTITAVNNLGTAS 16206
Score = 43.1 bits (100), Expect = 0.002
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 18028
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 18947
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 18948 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1718
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 22517 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 22573
Query: 1719 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 22574 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 22632
Query: 1779 V 1779
V
Sbjct: 22633 V 22633
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1321
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 25983 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 26041
Query: 1322 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1352
V+ L EY++RV A N G S PS+ S L
Sbjct: 26042 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 26074
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1025 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1081
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2319
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
+++++ ED+G Y V
Sbjct: 2320 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2339
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2340 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2387
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2447
Query: 1262 PDP 1264
P
Sbjct: 2448 ITP 2450
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1691 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1744
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 11117 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 11174
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+I DV D +YTC E T TA+L+VE +
Sbjct: 11175 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 23576 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 23634
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 23635 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 23692
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKV 23715
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 990 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1038
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 3008 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3067
Query: 1039 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1098
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3068 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3126
Query: 1099 YKCVAKNDAGQAE 1111
Y VA + A+
Sbjct: 3127 YTVVAGGNVSTAK 3139
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 19703 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 19762
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 19763 KYILTLENSCGK 19774
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 21139
Query: 628 AWNSAGEVRTQAVLTVQ 644
A N GEV V+T+Q
Sbjct: 21140 ARNIVGEVGD--VITIQ 21154
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 507
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 22550 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 22609
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 564
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 22610 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 22656
Query: 565 -----VMDGSQVTMTVQVSGNPPPEVIW 587
+ DG + V ++W
Sbjct: 22657 AWKPPLQDGGSDIINYIVERRETSRLVW 22684
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 23229 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 23283
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+L I + DD +Y N +G+ T + E++
Sbjct: 23284 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 23318
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 25410 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 25468
Query: 727 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
+ N G + +++++ + P + SC+ +
Sbjct: 25469 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 25504
Score = 42.4 bits (98), Expect = 0.004
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 520 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK----VMDGSQVTMTV 575
+GQ V+ K S SE + + P + L+ DLK + G+ + + V
Sbjct: 29409 MGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMV 29468
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
VSG PPP + W G I + + + L + +V D G YT EA N +G+
Sbjct: 29469 SVSGRPPPVITWSKQG--IDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 29526
Query: 636 RTQAVLTVQE 645
++ V +
Sbjct: 29527 SATVLVKVYD 29536
Score = 42.0 bits (97), Expect = 0.005
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1089
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 12344
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
PED Y C DA + SC + V
Sbjct: 12345 DCTPEDIKTYTC----DAKDFKTSCNLNV 12369
Score = 42.0 bits (97), Expect = 0.005
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 12459 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 12517
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 12518 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 12548
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 12549 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 12598
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 12599 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 12636
Score = 42.0 bits (97), Expect = 0.005
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 17508 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 17567
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
L I+ DTG Y N+AG LTV
Sbjct: 17568 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 19363
Query: 721 GQYEILLKNRVGECSCQVSL 740
G Y I +N G S + L
Sbjct: 19364 GDYTITAENSSGSKSATIKL 19383
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 28368 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 28425
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 28426 YTLTVENNSGSKSITFTVKV 28445
Score = 42.0 bits (97), Expect = 0.005
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 570
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 29014 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 29064
Query: 571 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 630
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 29065 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 29124
Query: 631 SAGEVRTQAVLTVQEPHDGTQP 652
++G T+AV + + D P
Sbjct: 29125 ASG---TKAVSVMVKVLDSPGP 29143
Score = 42.0 bits (97), Expect = 0.005
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 29036 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 29085
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 29140
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 12522
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1793
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 12523 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 12570
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 23600 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 23657
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 23658 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 23713
Query: 122 TV 123
V
Sbjct: 23714 KV 23715
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 26253
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 26254 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 26292
Score = 41.6 bits (96), Expect = 0.007
Identities = 34/133 (25%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
TCE Q +E V K L PV T+G + T + P
Sbjct: 27517 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV---TIGPITVKELIITPEVDLSDIPG--- 27570
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
+V V+ G G+P+P ++WLK +PL+ S V S+ L I
Sbjct: 27571 ---AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAK 27627
Query: 225 QDDVGVYTCLVVN 237
++ G YT ++ N
Sbjct: 27628 KEHGGKYTVILDN 27640
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1744
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 33327 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 33385
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+LII DV D YT N G + T + + ++
Sbjct: 33386 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 33423
Score = 41.2 bits (95), Expect = 0.009
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 14384 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 14443
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 14444 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 14479
Score = 41.2 bits (95), Expect = 0.009
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 501
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 14387 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 14446
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++ D G YT EN LG + S V V
Sbjct: 14447 PKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 41.2 bits (95), Expect = 0.009
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 17573
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D +Y N+ G T L V
Sbjct: 17574 LRRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 24776
Query: 721 GQYEILLKNRVGECSCQVSL 740
GQY + L N G S +++
Sbjct: 24777 GQYILKLSNVGGTKSIPITV 24796
Score = 41.2 bits (95), Expect = 0.009
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 29057 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 29116
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y KN +G S V V D+P
Sbjct: 29117 KYTLTVKNASGTKAVSVMVKVLDSP 29141
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 3/93 (3%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F K + D V GS + G P V W KD+ I +S I E I+
Sbjct: 6929 FVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILE 6988
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+D A+Y+C N G+ C E +V +E
Sbjct: 6989 STI-EDYAQYSCLIENEAGQDIC--EALVSVLE 7018
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 535 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 13730
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 13731 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 13778
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 13695 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 13753
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y +AVN G AT E+ V
Sbjct: 13754 KRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1320
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 14084 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 14142
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSE 1345
V L Y FRV A N G S+
Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSD 14167
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 18899 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 18957
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 18958 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 22553 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 22612
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 22613 NYILKAKNVAGERSVTVNVKV 22633
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 23241 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 23299
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 23300 YGITVANVVGQKTASIEI 23317
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 24368
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + DD KYT A NS G AT +IV
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 25411 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 25470
Query: 630 NSAGEVRTQAVLTV 643
NSAG + + V
Sbjct: 25471 NSAGSITVPITIIV 25484
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 642 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 688
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 25767 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 25826
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 25827 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 25876
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 12287 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 12344
Query: 1751 DVCGDDDAKYTCKA 1764
D +D YTC A
Sbjct: 12345 DCTPEDIKTYTCDA 12358
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 17976
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 17977 GKYIISAKNSSGHAQ 17991
Score = 40.4 bits (93), Expect = 0.016
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCL 515
GQ + V+G P P ITW G+ + + + EL I++A+ DHG Y
Sbjct: 17923 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 17982
Query: 516 AENALGQVSCSAWVTVHEK 534
A+N+ G SA V V ++
Sbjct: 17983 AKNSSGHAQGSAIVNVLDR 18001
Score = 40.0 bits (92), Expect = 0.020
Identities = 46/201 (22%), Positives = 72/201 (35%), Gaps = 29/201 (14%)
Query: 1622 RRKWQKTGNAVRAIGRLS-----SMAMISGLSGRKSSTGS----PTSPLNAEKLESEEDV 1672
R +W K G ++ R S A++ K+ +G ++ ++ +S+ +
Sbjct: 8376 RIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTI 8435
Query: 1673 SQAFLEAVAEEKPHV--KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
A A +K V + +F + + VVE + A F K+ G P P V W K
Sbjct: 8436 KDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQL 8495
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE---- 1786
+ + L I D D Y C A N GE L V+ ++ E
Sbjct: 8496 NQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKIEG 8555
Query: 1787 --------------GEGEEEE 1793
G GEEEE
Sbjct: 8556 DLRAMLKKTPILKKGAGEEEE 8576
Score = 40.0 bits (92), Expect = 0.020
Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 21/180 (11%)
Query: 7 VASSHISKTSLSVDPSRVDSMPLTEAPA------FILPPRNLCIKEGATAKFEGRVRGYP 60
VA S +K+ +++ + P T+ A F+ P+++ + E TA F +V G P
Sbjct: 8423 VAGSDTTKSKVTIKDKPAVA-PATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481
Query: 61 EPQVTWHR-NGQPITSGGR-FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
P V W + + + GGR F+ G L I + D G Y C A N G +
Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEA--KLEIRDTTKTDSGLYRCVAFNEHGEIESN 8539
Query: 119 VELTV---------EGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG 168
V L V EG L + P++ K G+ +E ++ + K+A G
Sbjct: 8540 VNLQVDERKKQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYG 8599
Score = 40.0 bits (92), Expect = 0.020
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 17199 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 17258
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 17259 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 529 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 587
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 23204 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 23263
Query: 588 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 646
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 23264 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 23323
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 506
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y N G S V V ++ P P P+ + G++
Sbjct: 24774 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 24815
Score = 40.0 bits (92), Expect = 0.020
Identities = 20/73 (27%), Positives = 29/73 (39%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G V + + G PPP V W + + + E + L I +V DTG Y
Sbjct: 27286 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 27345
Query: 628 AWNSAGEVRTQAV 640
N GE ++ V
Sbjct: 27346 IENGVGEPKSSTV 27358
Score = 39.7 bits (91), Expect = 0.027
Identities = 71/346 (20%), Positives = 136/346 (39%), Gaps = 57/346 (16%)
Query: 800 VRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRAN 859
++ + K++V + E +VE + G+K K L E K P E++ ++
Sbjct: 10900 LKAIPKKKVPEKPQVPE-----KVELTPLKVPGGEKKVRKLLPER--KPEPKEEVVLKSV 10952
Query: 860 LQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTSKTPVPEKVPPP 905
L++ + +PK ++ KV P ++V+ +V ++ K P P KVP
Sbjct: 10953 LRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--RKIPEPTKVPEI 11010
Query: 906 KPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAET 965
KPA P LPA E A+ P +P+ PV P
Sbjct: 11011 KPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIAAPV--TVPVVG 11054
Query: 966 LKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQ 1025
K A E KP G P + + + ++ + + G + + +
Sbjct: 11055 KKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLK 11111
Query: 1026 GTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKTLKTT---KFII 1076
F ++++D+ + E G + +C VS P+T I W +G ++ + +FI
Sbjct: 11112 AVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSNIRESPKHRFIA 11168
Query: 1077 LSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 11169 DGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 11211
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1668 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 11991 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 12049
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 12050 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 12089
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 13672 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 13731
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 13732 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 39.7 bits (91), Expect = 0.027
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 17520 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 17579
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 17580 EYQITVSNAAGSKTVAVHLTV 17600
Score = 39.7 bits (91), Expect = 0.027
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 19/124 (15%)
Query: 446 SFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAG----VAELH 500
S +D V+ G+ F L+ V G P+P I WL + I+ + + CE A L
Sbjct: 23626 SMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES-ARCEIKNTDFKALLI 23684
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
++DA+ D G Y A N G S V V ++ P P P+ + G+
Sbjct: 23685 VKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-------------PGPPEGPVQVTGV 23731
Query: 561 SDLK 564
+ K
Sbjct: 23732 TSEK 23735
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 23993 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 24052
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 24053 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 24109
Query: 121 LTV 123
+ V
Sbjct: 24110 VKV 24112
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 29513
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y A+N +G+ + V V D P
Sbjct: 29514 KYTIEAENQSGKKSATVLVKVYDTP 29538
Score = 39.3 bits (90), Expect = 0.035
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 710
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 711 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 770
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 771 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 824
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 825 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 884
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 885 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 936
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPA 963
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 14376 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 14435
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
D + L + D YT N LG AT + + V
Sbjct: 14436 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 14476
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 506
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 15109 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 15168
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 15169 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 15223
Query: 567 DGSQVT 572
GS++T
Sbjct: 15224 GGSEIT 15229
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 716
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 15882
Query: 717 PWHAGQYEILLKNRVGE--CSCQVSLM 741
H G+Y I KN+ G+ +C+V +M
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVM 15909
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 599 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 22495 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 22551
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 22552 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 22607
Query: 717 PWHAGQYEILLKNRVGECSCQVSL 740
+G Y + KN GE S V++
Sbjct: 22608 RVDSGNYILKAKNVAGERSVTVNV 22631
Score = 38.9 bits (89), Expect = 0.045
Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
++V +G A K G + WFKD Q + ++I + + IIS D
Sbjct: 4588 IDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTE-KKDS 4646
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
+YT + N +G ++C A + V
Sbjct: 4647 GEYTFEVQNDVGRSSCKARINV 4668
Score = 38.9 bits (89), Expect = 0.045
Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 1/81 (1%)
Query: 1699 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1758
+ + S F ++G P ++ WFKDD + I E L + V
Sbjct: 5340 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGL-EGSTSFLNLYSVDASKTG 5398
Query: 1759 KYTCKAVNSLGEATCTAELIV 1779
+YTC N +G +CT L+V
Sbjct: 5399 QYTCHVTNDVGSDSCTTMLLV 5419
Score = 38.9 bits (89), Expect = 0.045
Identities = 56/243 (23%), Positives = 87/243 (35%), Gaps = 50/243 (20%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 11464 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 11512
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 11513 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 11557
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 11558 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 11594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V S
Sbjct: 11595 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSST 11653
Query: 242 ASM 244
A +
Sbjct: 11654 AQL 11656
Score = 38.9 bits (89), Expect = 0.045
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
FA L V V E + RF C +T + V W KG ++ S + + +L I+
Sbjct: 11488 FAVPLKDVTVPERRQARFECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVIND 11545
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
DD GVYT V GK + SA L + G+
Sbjct: 11546 SQFDDEGVYTAEV---EGKKT-SARLFVTGI 11572
Score = 38.9 bits (89), Expect = 0.045
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 17977
Query: 623 TYTCEAWNSAGEVRTQAVLTV 643
Y A NS+G + A++ V
Sbjct: 17978 KYIISAKNSSGHAQGSAIVNV 17998
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 1/124 (0%)
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 687
A N+ G + V E + P I P +T G+ + I + G P PT W +
Sbjct: 18875 ARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-K 18933
Query: 688 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
G+ + H V + + L++K V +G Y + +N G + ++ +++ ++
Sbjct: 18934 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 18993
Query: 748 RALP 751
P
Sbjct: 18994 PPQP 18997
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 27280 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 27338
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 27339 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 27372
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 27578 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 27637
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
+NA+ +++ V L P PSKP PI
Sbjct: 27638 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 27664
Score = 38.5 bits (88), Expect = 0.059
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1146 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 921 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 978
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 979 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 38.5 bits (88), Expect = 0.059
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 545 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 15092 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 15150
Query: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+ GT+ L I++ +D G Y A NS G
Sbjct: 15151 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 15183
Score = 38.5 bits (88), Expect = 0.059
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 18211 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 18268
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 18269 SDGGKYVVTATNTAGS 18284
Score = 38.5 bits (88), Expect = 0.059
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 22148 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 22206
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 22261
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 22262 ---WG--PPKY 22267
Score = 38.5 bits (88), Expect = 0.059
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 23632 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 23690
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y +A N G
Sbjct: 23691 IDGGQYILRASNVAG 23705
Score = 38.5 bits (88), Expect = 0.059
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 28657 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 28716
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 28717 RYFLTLENTAGVKTFSVTVVVIG 28739
Score = 38.1 bits (87), Expect = 0.078
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 472 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 14325 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 14368
Query: 531 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 589
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 14369 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 14422
Query: 590 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 648
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 14423 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 14480
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 702
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 14481 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 14530
Query: 703 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
E+ + +K + P + + N+VG
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 14560
Score = 37.7 bits (86), Expect = 0.10
Identities = 51/198 (25%), Positives = 74/198 (37%), Gaps = 45/198 (22%)
Query: 47 GATAKFEGRVRGYPEPQVT-WHRNGQPITSGG--RFLLDCGIRGTFSLVIHAVHEEDRGK 103
G++A FE V P +T W ++G I RF+ D R L I V D G+
Sbjct: 11133 GSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDR---KLHIIDVQLSDAGE 11187
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
YTC G+ + T +L VE E P +F
Sbjct: 11188 YTCVLRLGNKEKTSTAKLVVE---------------------------------ELPVRF 11214
Query: 164 ATKLGR-VVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEIH 221
L V V +GQ SC++ + V W K G + ++ R+ M+ L I+
Sbjct: 11215 VKTLEEEVTVVKGQPLYLSCELN--KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTIN 11272
Query: 222 GVNQDDVGVYTCLVVNGS 239
+ D G YT V N +
Sbjct: 11273 DADDTDAGTYTVTVENAN 11290
Score = 37.7 bits (86), Expect = 0.10
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 551 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 603
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 15395 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 15454
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
+ + L I + ED GTYT A N G V
Sbjct: 15455 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 15486
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 21471 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 21530
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 21531 AYTLTATNPGGFA 21543
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 24703 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 24762
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 24763 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 24798
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 548 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 594
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 25771 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 25830
Query: 595 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+E L +++ DTG Y N AG
Sbjct: 25831 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 25869
Score = 37.7 bits (86), Expect = 0.10
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 562 DLKVMDGSQVTMTV--------QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
DL + G+QVT+ + G P P + WL +G ++ESE F + + +L I
Sbjct: 27564 DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSI 27623
Query: 614 QEVFPEDTGTYT 625
+ E G YT
Sbjct: 27624 KNAKKEHGGKYT 27635
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 27970 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 28029
Query: 1100 KCVAKNDAGQAECSCQVTVDDAP 1122
AKN +G A+ +V V D P
Sbjct: 28030 TVEAKNASGSAKAEIKVKVQDTP 28052
Score = 37.7 bits (86), Expect = 0.10
Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 8/188 (4%)
Query: 595 QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT---VQEPH-DG 649
Q+ DF E T Q + ++ + + + +A N AG + + ++EP +
Sbjct: 28586 QKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 28645
Query: 650 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 709
T + +T G I I+G P P V W + L K+T + +D T
Sbjct: 28646 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTT 28704
Query: 710 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARAL-PRGREPASCED-LCGGGV 767
L +K +G+Y + L+N G + V++++ P S E + G
Sbjct: 28705 LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGE 28764
Query: 768 GADGGGSD 775
DGGG++
Sbjct: 28765 PKDGGGTE 28772
Score = 37.7 bits (86), Expect = 0.10
Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
GS T+ V +SG P P+V W ++E++ + +L +++ D+G Y
Sbjct: 28662 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 28721
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
N+AG V+T +V V G ++ P V++ +S ++S
Sbjct: 28722 LENTAG-VKTFSVTVVVIGRPGP----VTGPIEVSSVSAESCVLS 28761
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1756
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 15170
Query: 1757 DAKYTCKAVNSLGEATCTAELIV 1779
+Y A NS G A + V
Sbjct: 15171 HGRYVITATNSCGSKFAAARVEV 15193
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 6/123 (4%)
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ +A N+AG + A + + P I + G +V I I G PFPT+
Sbjct: 16089 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 16148
Query: 684 HWLR------DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 737
W + D K H L +D TLV+ + + G Y I N +G S +
Sbjct: 16149 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 16208
Query: 738 VSL 740
+ L
Sbjct: 16209 MRL 16211
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 17976
Query: 721 GQYEILLKNRVG 732
G+Y I KN G
Sbjct: 17977 GKYIISAKNSSG 17988
Score = 37.4 bits (85), Expect = 0.13
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 19310 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369
Query: 516 AENALGQVSCSAWVTVHEK 534
AEN+ G S + + V +K
Sbjct: 19370 AENSSGSKSATIKLKVLDK 19388
Score = 37.4 bits (85), Expect = 0.13
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 22538 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 22589
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 22590 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 22648
Query: 139 TLGDR 143
++
Sbjct: 22649 VTAEK 22653
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1671 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 26167 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 26225
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 26226 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 26276
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 26482 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 26540
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 26541 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 27973 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 28031
Query: 726 LLKNRVGECSCQVSLMLQNSSARAL 750
KN G ++ + +Q++ + +
Sbjct: 28032 EAKNASGSAKAEIKVKVQDTPGKVV 28056
Score = 37.0 bits (84), Expect = 0.17
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1009 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1068
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1821 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1880
Query: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1126
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1881 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1939
Query: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1940 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1995
Query: 1187 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1221
EL K + IT +K RK+ + E + K +E
Sbjct: 1996 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2055
Query: 1222 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1271
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2056 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2109
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1331
WY + IE D W E C ++D+ +
Sbjct: 2110 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2147
Query: 1332 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1382
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2148 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2207
Query: 1383 VTINTEQKVSDFY 1395
E D Y
Sbjct: 2208 YKDGMEVHEGDKY 2220
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 16539 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 16596
Query: 628 AWNSAGEVRTQAVLTV 643
A N AGE + ++ V
Sbjct: 16597 AKNEAGERKKTIIVDV 16612
Score = 37.0 bits (84), Expect = 0.17
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1750
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 17913 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 17969
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA 1775
+ D KY A NS G A +A
Sbjct: 17970 EAVRADHGKYIISAKNSSGHAQGSA 17994
Score = 37.0 bits (84), Expect = 0.17
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1680 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1733
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 18187 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 18246
Query: 1734 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++ D + S ++ D KY A N+ G A + V
Sbjct: 18247 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 37.0 bits (84), Expect = 0.17
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 18908 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 18967
Query: 623 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 654
Y+ A NS+G + + V + QP F
Sbjct: 18968 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 18999
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 23008
Query: 1758 AKYTCKAVNSLG 1769
KYT NS G
Sbjct: 23009 GKYTLTLENSSG 23020
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1689 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 26928
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
S++I D + Y K N++G A+ T
Sbjct: 26929 SILIKDADRLNSGCYELKLRNAMGSASAT 26957
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 26882 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 26941
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 26942 CYELKLRNAMGSA--SATIRVQILD 26964
Score = 36.6 bits (83), Expect = 0.23
Identities = 17/77 (22%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
++P + + ++D+ + EG C+ P+ + WF++ + ++ + + + +
Sbjct: 8743 IEPAWERHLQDVTLKEGQTCTMTCQFS-VPNVKSEWFRNGRILKPQGRHKTEVEHKVH-K 8800
Query: 1747 LIISDVCGDDDAKYTCK 1763
L I+DV +D +YTCK
Sbjct: 8801 LTIADVRAEDQGQYTCK 8817
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 12982 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 13041
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 13042 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 13086
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 16186
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 16187 RRSDTGLYTITAVNNLGTASKEMRLNVLG 16215
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 18616 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 18674
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y+ +VN +G+ ++ + +
Sbjct: 18675 KYSLTLVNPAGEKAVFVNVRV 18695
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 574
A+N G +S + T + K EY P PT L + G + +
Sbjct: 20350 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 20400
Query: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 20401 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 20460
Query: 635 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
+TV + P IS + A+L
Sbjct: 20461 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 20491
Score = 36.6 bits (83), Expect = 0.23
Identities = 18/66 (27%), Positives = 29/66 (43%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + VSG PPP + W +G E++ + + +L ++ D+G YT
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 21535
Query: 628 AWNSAG 633
A N G
Sbjct: 21536 ATNPGG 21541
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 26488 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 26547
Query: 625 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 656
A NS+G + ++ + P T P IS
Sbjct: 26548 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 26580
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1674 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 28631 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 28689
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 28690 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 28737
Score = 36.2 bits (82), Expect = 0.29
Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 1/89 (1%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F K + D + +G + G P V W K+ ++ S+ I E + L I
Sbjct: 7870 FVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEK-SAILEIP 7928
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+D +Y C N+ G+ +C+A++++
Sbjct: 7929 SSTVEDAGQYNCYIENASGKDSCSAQILI 7957
Score = 36.2 bits (82), Expect = 0.29
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1007 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 12167 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 12225
Query: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 12226 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 12271
Score = 36.2 bits (82), Expect = 0.29
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 23634 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 23692
Query: 720 AGQYEILLKNRVGECSCQVSL 740
GQY + N G S V++
Sbjct: 23693 GGQYILRASNVAGSKSFPVNV 23713
Score = 36.2 bits (82), Expect = 0.29
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 718
++VT G S+ + +++G P P + W + G L + E L++ KV +
Sbjct: 29454 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 29510
Query: 719 HAGQYEILLKNRVGECSCQV 738
AG+Y I +N+ G+ S V
Sbjct: 29511 DAGKYTIEAENQSGKKSATV 29530
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD-DQSIRESRHFQIDYDEDGNCSL 1747
P F + L VV G A IEG V W K+ ++ IRES + +I + E+ +L
Sbjct: 5610 PRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVEN-VATL 5668
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ + KY C+ N G A L+V
Sbjct: 5669 QFAKAEPANAGKYICQIKNDGGMRENMATLMV 5700
Score = 35.8 bits (81), Expect = 0.38
Identities = 19/83 (22%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNCSLIISDVCGDD 1756
+ V G+ +C + G P+ WFKD + + +S+H ++ + + +++ D
Sbjct: 6654 MTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEM--SD 6711
Query: 1757 DAKYTCKAVNSLGEATCTAELIV 1779
Y+ + NS+G++ CT + V
Sbjct: 6712 KGLYSFEVKNSVGKSNCTVSVHV 6734
Score = 35.8 bits (81), Expect = 0.38
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 15351 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 15395
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 15396 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 15445
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 15446 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 15505
Query: 261 VRETKA 266
V + KA
Sbjct: 15506 VTDIKA 15511
Score = 35.8 bits (81), Expect = 0.38
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 17525 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 17583
Query: 726 LLKNRVGECSCQVSL 740
+ N G + V L
Sbjct: 17584 TVSNAAGSKTVAVHL 17598
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 20374 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 20434 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 20469
Score = 35.8 bits (81), Expect = 0.38
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 22954 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 23010
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 23011 YTLTLENSSGTKSAFVTVRV 23030
Score = 35.8 bits (81), Expect = 0.38
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + T SL
Sbjct: 25395 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 25453
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 25454 IKEASKEDVGTYELCVSNSAGS--ITVPITI 25482
Score = 35.8 bits (81), Expect = 0.38
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1713 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 27352
Score = 35.8 bits (81), Expect = 0.38
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1073
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 33315 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 33374
Query: 1074 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ L ++ I +D GLY N+ G + + +
Sbjct: 33375 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 35.4 bits (80), Expect = 0.50
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 12465 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 12523
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1150
A ED G Y C R P S +D
Sbjct: 12524 AHLEDAGNYNC---------------------------------RLPSS--------RTD 12542
Query: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 12543 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 12592
Query: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 12593 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 12639
Score = 35.4 bits (80), Expect = 0.50
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 16827 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 16886
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 16887 GKYCVVVENSTGSRKGFCQVNV 16908
Score = 35.4 bits (80), Expect = 0.50
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 607
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 18200 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 18257
Query: 608 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+ + D G Y A N+AG A + V
Sbjct: 18258 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 35.4 bits (80), Expect = 0.50
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 571
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 23593 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 23643
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 23644 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 23703
Query: 632 AG 633
AG
Sbjct: 23704 AG 23705
Score = 35.4 bits (80), Expect = 0.50
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---E 493
G V+++ ++ V+K A G L+ + G P P I W + + +Q C
Sbjct: 26868 GGPVIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENT 26924
Query: 494 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
+A + I+DA + G Y NA+G S + V + +K
Sbjct: 26925 TDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 26965
Score = 35.4 bits (80), Expect = 0.50
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 30146 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 30203
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 30204 TYDLVLENKCGKKAVYIKVRVIG 30226
Score = 35.4 bits (80), Expect = 0.50
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1747
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 32374 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 32431
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
I D DD Y N GEA+ A L V
Sbjct: 32432 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 11842 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 11899
Query: 1751 DVCGDDDAKYTCKA 1764
+D+AKY +A
Sbjct: 11900 SAAFEDEAKYMFEA 11913
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 16590
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 16591 GVYSLLAKNEAGE 16603
Score = 35.0 bits (79), Expect = 0.66
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 18618 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 18673
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 18674 GKYSLTLVNPAGEKAVFVNVRV 18695
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 19305 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 19363
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
YT A NS G + T +L V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385
Score = 35.0 bits (79), Expect = 0.66
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 546 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 19972 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 20031
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 652
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 20032 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 20082
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 20371 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 20420
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 20421 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 20459
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 26485 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 26543
Query: 720 AGQYEILLKNRVGECSCQVSLML 742
AG+YEI N G +++++
Sbjct: 26544 AGRYEITAANSSGTTKAFINIVV 26566
Score = 34.7 bits (78), Expect = 0.86
Identities = 18/82 (21%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
++V G A + + G P+ + W+KD + + S+ ++I + ++ L D
Sbjct: 4026 IQVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISF-KNNVAQLKFYSAELHDS 4084
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
+YT + N +G ++C V
Sbjct: 4085 GQYTFEISNEVGSSSCETTFTV 4106
Score = 34.7 bits (78), Expect = 0.86
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 623 TYTCEAWNSAGE----VRTQAVLTVQEPHDGTQPWFISKP---------RSVTASLGQSV 669
TYT + E VR + + EP T P P S+ G +
Sbjct: 14638 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEI 14697
Query: 670 LISCAIAGDPFPTVHWLRD 688
+ +I+G P+PT+ W++D
Sbjct: 14698 ALDASISGSPYPTITWIKD 14716
Score = 34.7 bits (78), Expect = 0.86
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 22558 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 22617
Query: 628 AWNSAGE 634
A N AGE
Sbjct: 22618 AKNVAGE 22624
Score = 34.7 bits (78), Expect = 0.86
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 25119 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 25174
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 25175 RYNLTLENNSGSKTAFVNVRV 25195
Score = 34.7 bits (78), Expect = 0.86
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 25393 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 25451
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + +D Y NS G T +IV
Sbjct: 25452 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484
Score = 34.3 bits (77), Expect = 1.1
Identities = 47/193 (24%), Positives = 71/193 (36%), Gaps = 18/193 (9%)
Query: 1597 PWLMKDTKNMEAKKLSKDRMKKYMA-----RRKWQKTGNAVRAIGRLSSMAMISGLSG-- 1649
P+ K +N+++ R+ +A R W K G + A R +A + G +
Sbjct: 4113 PFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYR-IAFVEGTASLE 4171
Query: 1650 --RKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR 1707
R + A +D S A + V E V SK +V+ GSA
Sbjct: 4172 IIRVDMNDAGNFTCRATNSVGSKDSSGALI--VQEPPSFVTKPGSK-----DVLPGSAVC 4224
Query: 1708 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1767
+G + WFK ++ + I E SL + V D YTCK N
Sbjct: 4225 LKSTFQGSTPLTIRWFKGNKELVSGGSCYIT-KEALESSLELYLVKTSDSGTYTCKVSNV 4283
Query: 1768 LGEATCTAELIVE 1780
G C+A L V+
Sbjct: 4284 AGGVECSANLFVK 4296
Score = 34.3 bits (77), Expect = 1.1
Identities = 27/97 (27%), Positives = 47/97 (48%), Gaps = 5/97 (5%)
Query: 1651 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKT-IRDLE---VVEGSAA 1706
K S T L E++E E + F E V+ + + T I+D+E V++ + A
Sbjct: 8614 KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA 8673
Query: 1707 RFDCKIE-GYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
F+ I+ YP+ ++ W+K + + S F+I D D
Sbjct: 8674 VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGD 8710
Score = 34.3 bits (77), Expect = 1.1
Identities = 45/214 (21%), Positives = 87/214 (40%), Gaps = 40/214 (18%)
Query: 810 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLK-EIPA----------EQMDFRA 858
+R+ EE ++ +V ++ + ++ +K S + E+ ++ ++PA E+M F +
Sbjct: 9193 SRRMEEEKVQVTKVPEVS-KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFAS 9251
Query: 859 NLQRQVK---PKTVSE--EERKVH---------SPQQVDFRSVLAKKGTSKTPVPEKVPP 904
+ + +V P+ E E K+H P+ + A + + P+P+KV P
Sbjct: 9252 HTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEP 9311
Query: 905 PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQ-PSGPLKPVGNAKPA 963
P P P+ KK +P E V +P + + P P KPV K
Sbjct: 9312 PAPKVPEV-----PKKPVPEEK--------KPVPVPKKEPAAPPKVPEVPKKPVPEEKIP 9358
Query: 964 ETLKPMGNAKPAETLKPMGNAKPDENLKSASKEE 997
+ A PA+ + +E + ++ E
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQRE 9392
Score = 34.3 bits (77), Expect = 1.1
Identities = 35/139 (25%), Positives = 57/139 (41%), Gaps = 25/139 (17%)
Query: 136 VSKTLGDRFSAPAVETRPSIWGECPP--------------KFATKLGRVVVKE----GQM 177
V K A + RP GE PP KF ++ +++ E G
Sbjct: 11076 VPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSS 11135
Query: 178 GRFSCKITGRPQPQVT-WLK--GNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCL 234
F C ++ P +T W+K N+ P R K+ + L I V D G YTC+
Sbjct: 11136 AIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKD--RKLHIIDVQLSDAGEYTCV 11191
Query: 235 VVNGSGKASMSAELSIQGL 253
+ G+ + + +A+L ++ L
Sbjct: 11192 LRLGNKEKTSTAKLVVEEL 11210
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 12646 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 12703
Query: 1755 DDDAKYTCKAVNSLGE-ATCTAELIVE 1780
DD A Y N GE A LIVE
Sbjct: 12704 DDQANYNVSLTNHRGENVKSAANLIVE 12730
Score = 34.3 bits (77), Expect = 1.1
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 13359 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 13416
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 13417 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 13471
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 18209 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 18268
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 18269 SDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1692 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1751
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 24028 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 24083
Query: 1752 VCGDDDA-KYTCKAVNSLG 1769
C +DA KY K NS G
Sbjct: 24084 NCDRNDAGKYILKLENSSG 24102
Score = 34.3 bits (77), Expect = 1.1
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 30122 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 30179
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 30180 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 30227
Score = 33.9 bits (76), Expect = 1.5
Identities = 51/246 (20%), Positives = 95/246 (38%), Gaps = 41/246 (16%)
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPE 507
L+D E Q+ V + + + + + W + I+ + + + +L + + + +
Sbjct: 2539 LRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKD 2597
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 567
D G YT A G+ S +TV A SKP L+D V +
Sbjct: 2598 DEGKYTFYA----GENMTSGKLTVAGG------------AISKP--------LTDQTVAE 2633
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
+ +V+ NP + WL +G + + + E G + L I +D G YT +
Sbjct: 2634 SQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYK 2692
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWL 686
S +T A L V+ I K +++T + Q + + + V W+
Sbjct: 2693 VATS----KTSAKLKVEAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWI 2741
Query: 687 RDGKAL 692
++G L
Sbjct: 2742 KNGVVL 2747
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 16590
Query: 721 GQYEILLKNRVGE 733
G Y +L KN GE
Sbjct: 16591 GVYSLLAKNEAGE 16603
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 21476 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 21534
Query: 1763 KAVNSLGEA 1771
A N G A
Sbjct: 21535 TATNPGGFA 21543
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 21841 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 21898
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 21899 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 21948
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 22952 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 23009
Query: 623 TYTCEAWNSAG 633
YT NS+G
Sbjct: 23010 KYTLTLENSSG 23020
Score = 33.9 bits (76), Expect = 1.5
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+ + I + G P P + W++DG+ L K T V + L +K+ G+Y +
Sbjct: 24326 GEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 24384
Query: 726 LLKNRVGECSCQVSLML 742
N G + +S+++
Sbjct: 24385 TATNSAGTATENLSVIV 24401
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 27547 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 27606
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 27607 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 27651
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCL 515
G F + + G P P++TW L ++ T L ++D++ D G Y
Sbjct: 28662 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 28721
Query: 516 AENALGQVSCSAWVTV 531
EN G + S V V
Sbjct: 28722 LENTAGVKTFSVTVVV 28737
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1676 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1725
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 29428 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 29482
Query: 1726 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 29483 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 29529
Score = 33.5 bits (75), Expect = 1.9
Identities = 34/132 (25%), Positives = 49/132 (37%), Gaps = 3/132 (2%)
Query: 847 KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTP-VPEK-VPP 904
KE+ E++ F + V+ V EEE +H ++ + K P VP K VP
Sbjct: 9901 KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960
Query: 905 PKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAE 964
K P + K+P E E + + KP P P KPV K
Sbjct: 9961 EKKPVPVPKKKEAPPAKVP-EVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPV 10019
Query: 965 TLKPMGNAKPAE 976
+ A PA+
Sbjct: 10020 PVPKKVEAPPAK 10031
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 11576 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 11633
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+V DD ++ + + E + TA+L V
Sbjct: 11634 EVTLDDISQIKAQ----VKELSSTAQLKV 11658
Score = 33.5 bits (75), Expect = 1.9
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 11931 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 11988
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCT 1774
D+ DD ++ +A+ EA T
Sbjct: 11989 DLSIDDTSQIRVEAMGMSSEAKLT 12012
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 13419 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 13478
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 13479 EIDVNVIARPSA 13490
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 14372 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 14423
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 14424 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 14478
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 513
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 18216 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 18275
Query: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
A N G A V V +K ++ ++ V+ + T
Sbjct: 18276 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 18314
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 19701 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 19756
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 19757 NKYDAGKYILTLENSCGKKEYTIVVKV 19783
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 21473 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 21531
Query: 104 YTCEATNGSG 113
YT ATN G
Sbjct: 21532 YTLTATNPGG 21541
Score = 33.5 bits (75), Expect = 1.9
Identities = 33/148 (22%), Positives = 53/148 (35%), Gaps = 5/148 (3%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 25799 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 25857
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 25858 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 25917
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKIT 185
K T + EG++ SCK+T
Sbjct: 25918 YIVEKRETSHLAWTICEGELQMTSCKVT 25945
Score = 33.5 bits (75), Expect = 1.9
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 26157 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 26214
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 26215 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 26271
Query: 121 LTV 123
+ V
Sbjct: 26272 VKV 26274
Score = 33.5 bits (75), Expect = 1.9
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 503
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 26246
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTV 531
A D G YT +N L S + V V
Sbjct: 26247 ANRNDSGKYTLTIQNVLSAASLTLVVKV 26274
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 26196 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 26253
Query: 623 TYTCEAWN 630
YT N
Sbjct: 26254 KYTLTIQN 26261
Score = 33.1 bits (74), Expect = 2.5
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2513 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2560
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2561 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2615
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2616 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2640
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2641 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2699
Query: 242 ASMSAE 247
A + E
Sbjct: 2700 AKLKVE 2705
Score = 33.1 bits (74), Expect = 2.5
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1656 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1701
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 11616 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 11675
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 11676 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 11732
Query: 1762 CKAVNSLGEATCTAE 1776
C +A T E
Sbjct: 11733 CDCGTDKTKANVTVE 11747
Score = 33.1 bits (74), Expect = 2.5
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1091
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 15408 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 15467
Query: 1092 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
+ ED+G Y A N G + V V D P+
Sbjct: 15468 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499
Score = 33.1 bits (74), Expect = 2.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 17226 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 17282
Query: 1756 DDAKYTCKAVNSLGEATCTAELIV 1779
D Y+ N G T + +++V
Sbjct: 17283 DGGIYSLTVENPAGSKTVSVKVLV 17306
Score = 33.1 bits (74), Expect = 2.5
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 506
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 25854
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 25855 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 25896
Score = 33.1 bits (74), Expect = 2.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG 113
+G P P VTW ++ + + S R+ ++ + L I V D GKY NG G
Sbjct: 27296 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVG 27351
Score = 33.1 bits (74), Expect = 2.5
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 28369 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 28424
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 28425 KYTLTVENNSGSKSITFTVKV 28445
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2362 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2419
Query: 1755 DDDAKYTCKAVNSLGEAT 1772
+D Y+ + +LG +T
Sbjct: 2420 EDAGNYSF-TIPALGLST 2436
Score = 32.7 bits (73), Expect = 3.3
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F K + D V G + + G V W KD +I S I E C L I
Sbjct: 5988 FLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEK-TCILEIL 6046
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+ D +Y+C+ N G C A +V T+E
Sbjct: 6047 NSTKRDAGQYSCEIENEAGRDVCGA--LVSTLE 6077
Score = 32.7 bits (73), Expect = 3.3
Identities = 50/218 (22%), Positives = 85/218 (38%), Gaps = 16/218 (7%)
Query: 791 WLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIP 850
W E+ E V + R E + E + + EV + ++ +K+ + K +
Sbjct: 9495 WSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIIS------KRVE 9548
Query: 851 AEQMDFRANLQRQV--KPKTVSE-EERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKP 907
AE + ++++ KPK ++ EE + + V KK + P EKVPPPK
Sbjct: 9549 AEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPK- 9607
Query: 908 ATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKP-AETL 966
P+ +KK+P + E L AK E ++ + A P A
Sbjct: 9608 -VPEEPKKPVPEKKVPPK-VIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVP 9665
Query: 967 KPMGNAKPAE---TLKPMGNAKPDENLKSASKEELKKD 1001
+ A P E LKP +P + K +K++
Sbjct: 9666 EEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEE 9703
Score = 32.7 bits (73), Expect = 3.3
Identities = 76/338 (22%), Positives = 111/338 (32%), Gaps = 62/338 (18%)
Query: 863 QVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSK--------TPVPEKVPPPKPATPDFRS 914
+V K V E++ V +P++V+ + K TPVP+KV P P P R
Sbjct: 10034 EVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKRE 10093
Query: 915 VLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKP 974
+ LP E E + V + L + P + + E L P
Sbjct: 10094 PVPVPVALPQEEEVLFEEEI----VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPP 10149
Query: 975 AETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQK 1034
E P E + +EE+ +VK V P K+K
Sbjct: 10150 EEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKV----------------PVPAPVPEIKKK 10193
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI------ 1088
+ + V KK PPA + K IIL +E + V +
Sbjct: 10194 VTEKKVVIPKK-------EEAPPAKV---PEVPKKVEEKRIILPKEEEVLPVEVTEEPEE 10243
Query: 1089 ----EKALPEDRGLYK-----------CVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1133
E+ +PE+ + V K +A V+ PA + K PE K
Sbjct: 10244 EPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303
Query: 1134 SRRP--KSSLPPVLGTESDATVKKKPAPKTPPKAAMPP 1169
P K PP E V +K P K A+PP
Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKV-LVPKKEAVPP 10340
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1094
G ++ + + P W +GK K K + L + + I +
Sbjct: 15825 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 15884
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
G Y AKN AGQ +C+V V D P
Sbjct: 15885 HTGKYSITAKNKAGQKTANCRVKVMDVP 15912
Score = 32.7 bits (73), Expect = 3.3
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1761
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 29062 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 29119
Query: 1762 CKAVNSLG 1769
N+ G
Sbjct: 29120 LTVKNASG 29127
Score = 32.3 bits (72), Expect = 4.3
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1696 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1753
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 12559 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 12614
Query: 1754 GDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y V +G A A L V
Sbjct: 12615 LQDMGTY----VVMVGAARAAAHLTV 12636
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 545 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 16808 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 16867
Query: 603 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 633
+ T +L ++++ + D+G Y NS G
Sbjct: 16868 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 16898
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
I G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 20006 IKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 20064
Query: 735 SCQVSL 740
+S+
Sbjct: 20065 EGTISI 20070
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 506
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 21468 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 21526
Query: 507 EDHGTYTCLAENALG 521
D G YT A N G
Sbjct: 21527 RDSGAYTLTATNPGG 21541
Score = 32.3 bits (72), Expect = 4.3
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 515
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 26491 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 26550
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 566
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 26551 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 26597
Query: 567 DGSQVT 572
GSQVT
Sbjct: 26598 GGSQVT 26603
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 26929
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
+ I++ ++G Y + N+ G A + VQ
Sbjct: 26930 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 26961
Score = 32.3 bits (72), Expect = 4.3
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 29743 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 29801
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 29802 TIRDTGEYTLELKNVTGTTSETIKVII 29828
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1691 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2233
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ D Y+C V T TA+LIVE
Sbjct: 2234 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2263
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1625 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1677
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2388 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2445
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2446 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2492
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1750
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 18666
Query: 1751 DVCGDDDAKYTCKAVNSLGE 1770
+ DD KY+ VN GE
Sbjct: 18667 NSTRDDSGKYSLTLVNPAGE 18686
Score = 32.0 bits (71), Expect = 5.6
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 717
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 20839
Query: 718 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 750
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 20840 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 20872
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 24773
Query: 1755 DDDAKYTCKAVN 1766
D +Y K N
Sbjct: 24774 TDGGQYILKLSN 24785
Score = 32.0 bits (71), Expect = 5.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 28660 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 28718
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 28719 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 28770
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 28771 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 28823
Score = 31.6 bits (70), Expect = 7.3
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 20054
Query: 1762 CKAVNSLG--EATCTAELI 1778
N G E T + +++
Sbjct: 20055 ITLKNVAGTKEGTISIKVV 20073
Score = 31.6 bits (70), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAE--LHIQDALPEDHGTYTC 514
E +F L+ ++G P P ++W P+ R + E+ L + D D G YT
Sbjct: 19996 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 20055
Query: 515 LAENALG 521
+N G
Sbjct: 20056 TLKNVAG 20062
Score = 31.6 bits (70), Expect = 7.3
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 625
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 24722 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 24780
Query: 626 CEAWNSAG 633
+ N G
Sbjct: 24781 LKLSNVGG 24788
Score = 31.2 bits (69), Expect = 9.5
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 1089 EKALPEDRGLYKCVAKND--AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1146
EK +P + K V + + A E ++ V+ E + PE + R P + +P VL
Sbjct: 10447 EKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE-----EKVRVPE-EPRVPPTKVPEVLP 10500
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPED 1177
+ KK P P A PP++ + P++
Sbjct: 10501 PKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE 10531
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1007 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1066
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 12533 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 12588
Query: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 12589 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 12636
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALP 506
+L V G L +V G P P+ITW + Q R T E + + I D+
Sbjct: 13696 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 13755
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEK 534
D GTY A N G+ + V V +K
Sbjct: 13756 SDTGTYIIEAVNVCGRATAVVEVNVLDK 13783
Score = 31.2 bits (69), Expect = 9.5
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 10/79 (12%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLL-------NGQPIQYARSTCEAGVAE---LHIQDAL 505
V EG + + ++G P P +TW N +P+ Y + V + L I +
Sbjct: 16128 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 16187
Query: 506 PEDHGTYTCLAENALGQVS 524
D G YT A N LG S
Sbjct: 16188 RSDTGLYTITAVNNLGTAS 16206
Score = 31.2 bits (69), Expect = 9.5
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 20784 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 20840
Query: 1756 DDAKYTCKAVNSLGE 1770
D K+ N G+
Sbjct: 20841 DTGKFVMTIENPAGK 20855
Score = 31.2 bits (69), Expect = 9.5
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 20786 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 20837
Query: 617 FPEDTGTYTCEAWNSAGE 634
DTG + N AG+
Sbjct: 20838 NRYDTGKFVMTIENPAGK 20855
Score = 31.2 bits (69), Expect = 9.5
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1761
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 21137
Query: 1762 CKAVNSLGE 1770
A N +GE
Sbjct: 21138 LTARNIVGE 21146
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 21470 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 21528
Query: 720 AGQYEILLKNRVG 732
+G Y + N G
Sbjct: 21529 SGAYTLTATNPGG 21541
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 25796 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 25854
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y N G
Sbjct: 25855 RDTGQYVLTLKNVAG 25869
Score = 31.2 bits (69), Expect = 9.5
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 26486 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 26545
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 26546 RYEITAANSSG 26556
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1761
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 28372 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 28427
Query: 1762 CKAVNSLGEATCT 1774
N+ G + T
Sbjct: 28428 LTVENNSGSKSIT 28440
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 514
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 30148 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 30207
Query: 515 LAENALGQ 522
+ EN G+
Sbjct: 30208 VLENKCGK 30215
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1085
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ I +D +Y+ A N G + + V+
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24715
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
P K +P + +R GE V + +G TW K
Sbjct: 24716 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24759
Query: 1206 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 24760 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24819
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1324
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 24820 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24878
Query: 1325 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1384
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 24879 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24935
Query: 1385 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1444
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 24936 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24994
Query: 1445 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1504
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 24995 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 25054
Query: 1505 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1564
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 25055 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25114
Query: 1565 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1585
++ + ATDMWS+G + Y+L
Sbjct: 25115 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25174
Query: 1586 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1633
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 25175 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25233
Query: 1634 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1693
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 25234 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25281
Query: 1694 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 25282 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25326
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
DD Y CK VN GE + AEL V+ + E
Sbjct: 25327 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25358
Score = 166 bits (420), Expect = 2e-40
Identities = 161/707 (22%), Positives = 277/707 (39%), Gaps = 57/707 (8%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 26443 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26502
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 26503 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26557
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 26558 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26617
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
TC V N +G S S +L+I+ + V K S++ + V+ +E + A
Sbjct: 26618 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQK--TSEITPQKKAVVQEEIS----QKA 26671
Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK--TSSSITLQA 349
+S+ + A + S E K S T+ + ++ + T +S +
Sbjct: 26672 LRSEEIKMSEAKSQEKLALKEEASKVLIS--EEVKKSAATSLEKSIVHEEITKTSQASEE 26729
Query: 350 ARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT---FPTRQPGLGSQD-----VVSKAANR 401
R E +A + G+ A AT + L + + V
Sbjct: 26730 VRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTL 26789
Query: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQD 461
I RD SK + VK + E + AP+F S + + EGQ+
Sbjct: 26790 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE----LSDAPAFISQPRSQNINEGQN 26845
Query: 462 FVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAEN 518
+ C + G P P I W N PI + + V L I++A D G YT A+N
Sbjct: 26846 VLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 26905
Query: 519 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
GQ S +A S +LP+ +P+ + L+ D + GS + +VQ+S
Sbjct: 26906 FRGQCSATA------------SLMVLPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMS 26951
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 638
+ + + + F Q +QE F E + + N ++ +
Sbjct: 26952 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESS 27010
Query: 639 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTG 697
++ G P + P ++ G+ + ++CA G+P P V W G+ + ++ G
Sbjct: 27011 TSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQG 27070
Query: 698 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 744
F + +D+ TL++ VQ G Y + L N G S V++ +++
Sbjct: 27071 RFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27117
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 23846 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23902
Query: 726 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 779
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 23903 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23958
Query: 780 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 837
+ W + VRG +++ E R Q L + V+
Sbjct: 23959 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 24016
Query: 838 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 894
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 24017 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24075
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 953
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 24076 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24131
Query: 954 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1001
L+ + +K + TL KP K D K ++KE +K
Sbjct: 24132 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24191
Query: 1002 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 24192 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24250
Query: 1052 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1111
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 24251 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24310
Query: 1112 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
S ++ + P P P K
Sbjct: 24311 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24330
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1230
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 24331 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24386
Query: 1231 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 24387 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24446
Query: 1291 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 24447 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24506
Query: 1349 ESELTTVGEKPEEP 1362
S + + E+P
Sbjct: 24507 VSSVVIIKSPFEKP 24520
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 645
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 646 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 691 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 748 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 806
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 807 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 863
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242
Query: 864 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 912
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 913 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 966
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350
Query: 967 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1026
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407
Query: 1027 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1083
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467
Query: 1084 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1143
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504
Query: 1144 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1203
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544
Query: 1204 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1258
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604
Query: 1259 VDKPDP------PAGTPCASDIRSSSL 1279
+P+P P GT A +I + L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631
Score = 118 bits (295), Expect = 6e-26
Identities = 146/697 (20%), Positives = 242/697 (34%), Gaps = 145/697 (20%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP+ +L V V+ G+ RF I+GRPQP+++W K L + L
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
+ +D VYTC N G A+ T++ + EV V+
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVAT-----------------------TSASLSVEVPEVV 3288
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ 339
S + ++ A + + G P A Q + S + + +
Sbjct: 3289 SPDQEMPVYPPAIITPLQDTVTSEGQP---ARFQCRVSGTDLKVSWYSKDKKIKPSRFFR 3345
Query: 340 KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAA 399
T T Q + P G S + + A L Q K
Sbjct: 3346 MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSST---ANLSLEVQALDRQSS-GKDV 3401
Query: 400 NRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFR------------------------- 434
+ DS+F K ESK +E+K Q +
Sbjct: 3402 RESAKSQAVADSSFTKEESKISQKEIKSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQL 3461
Query: 435 CEGLAVMEVAPSFSSVLKDCA----------VIEGQDFVLQCS--------VRGTPVPRI 476
C ++ ++A S + + K+CA + QD ++C ++ +
Sbjct: 3462 CHTASLSQIAES-TELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDV 3520
Query: 477 TWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH- 532
TW G I+ + + + + L I + D G Y+C+ N G+ + SA ++V
Sbjct: 3521 TWTHEGAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEG 3580
Query: 533 ----------------------------EKKSSRKSEYLL-------------PVAPSK- 550
E++ +E L PV P+K
Sbjct: 3581 APESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVYPTKF 3640
Query: 551 -----PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
T PIF++ +S+ + G T++V V G P P++ W NG + S D+ F
Sbjct: 3641 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3700
Query: 606 GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ---EPHDGTQ----------- 651
G HSL I ED G YTC A N G+ A L + E H T+
Sbjct: 3701 GDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEK 3760
Query: 652 ------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNE 705
P F+ + + + + G + + G+P PTV W ++ K LC + +
Sbjct: 3761 LGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPN 3820
Query: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 742
T ++ Q +G Y +N +GE +C L++
Sbjct: 3821 GSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 26048 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26107
Query: 593 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 613
E+QES D H + GT ++C
Sbjct: 26108 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26167
Query: 614 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 649
+ VFPE T T EA +S EV++Q T + H
Sbjct: 26168 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26227
Query: 650 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 26228 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26287
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 26288 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346
Query: 744 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 779
+ + ++ R + P +++
Sbjct: 26347 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26406
Query: 780 LRPGWPARGQGWLEEEDGEDVR--------GVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 26407 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466
Query: 832 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 885
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526
Query: 886 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 914
S + +K K P P P P+P T D ++
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26586
Query: 915 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 946
+ GGK KL + G SS+ L KA++ ++
Sbjct: 26587 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26646
Query: 947 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 998
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 26647 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26703
Query: 999 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 26704 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26761
Query: 1059 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 26762 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821
Query: 1119 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178
+ E+ SDA P I P Q
Sbjct: 26822 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26838
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 26839 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26898
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 26899 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26958
Query: 1299 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1354
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 26959 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 27016
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEV 1378
G + PK E SD E +V
Sbjct: 27017 AGIRGIPPKIEALPSDISIDEGKV 27040
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 12593 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12651
Query: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1286
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 12652 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12711
Query: 1287 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 12712 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12771
Query: 1346 PSQESELTTVGE--KPEEPKD 1364
P ++ P EPK+
Sbjct: 12772 PLTSPKMVAQFPFGVPSEPKN 12792
Score = 110 bits (276), Expect = 9e-24
Identities = 154/692 (22%), Positives = 268/692 (38%), Gaps = 99/692 (14%)
Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
+V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG +
Sbjct: 4463 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4519
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+LTV A PV+ + K+ + V G + +
Sbjct: 4520 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4547
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F+C+I P + W K + S + S+ + LEI D G YTC N
Sbjct: 4548 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4607
Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
G S +A L ++ G + R + E K + ++EV +V+ K + + + K
Sbjct: 4608 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4664
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
+ P PP P+P E ++ + R P+ + + +I L A +P
Sbjct: 4665 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4718
Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
+P A + P E P P T P ++ +AA + P++G
Sbjct: 4719 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4777
Query: 415 KFES-----KPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE----GQDFVLQ 465
E+ +P S K F + + V F +KD + E G + +
Sbjct: 4778 PIEAERRKLRPGSGGEKPPDEAPFTYQ---LKAVPLKFVKEIKDIILTESEFVGSSAIFE 4834
Query: 466 CSVRGTPVPRI-TWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALG 521
C V +P I TW+ +G I+ + R + +LHI D D G YTC+
Sbjct: 4835 CLV--SPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 4892
Query: 522 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGN 580
+ + +A + V E LPV F++ L ++ V+ G + ++ ++ N
Sbjct: 4893 EKTSTAKLVVEE----------LPVR--------FVKTLEEEVTVVKGQPLYLSCEL--N 4932
Query: 581 PPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 639
+V+W +G + E G +L I + D GTYT N+ +
Sbjct: 4933 KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSC 4992
Query: 640 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGH 698
V V+ D W + R + + +C IA D P + W + + +
Sbjct: 4993 VKVVEVIRD----WLVKPIRDQHVKPKGTAIFACDIAKDT-PNIKWFKGYDEIPAEPNDK 5047
Query: 699 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
E+L++ + L +K P +Y + ++ +
Sbjct: 5048 TEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 5079
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 498
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQ 644
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 7397 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7456
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 7457 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7515
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1357
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 7516 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7575
Query: 1358 KPEEPKDEVEVSD 1370
P P +E SD
Sbjct: 7576 DPPGPPTRLEPSD 7588
Score = 107 bits (266), Expect = 1e-22
Identities = 159/700 (22%), Positives = 240/700 (34%), Gaps = 154/700 (22%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
K ++ P F+ K S +K F C +
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPI--------------- 1683
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512
G P + WL +G+P++ A R E G L A D G
Sbjct: 1684 --------------GDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGII 1729
Query: 513 TCLAENALGQVSCSAWVTVHEKKSSRKSEYL------------------------LPVAP 548
TC A N G SA + V ++KS + L +
Sbjct: 1730 TCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQ 1789
Query: 549 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 608
+ P + ++V++G +V+G P P+V W NG I++S+ F G
Sbjct: 1790 KEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI- 1848
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
H L I + DTG A N G + + L +Q+ D
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 102 bits (253), Expect = 4e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 20571 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20630
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 20631 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20690
Query: 1292 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 20691 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20747
Query: 1348 QESEL 1352
+ +
Sbjct: 20748 ESDSV 20752
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1167 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 11201 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11260
Query: 1224 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1283
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 11261 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11320
Query: 1284 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1342
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 11321 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11380
Query: 1343 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1400
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 11381 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11438
Query: 1401 LGSGKFGQV 1409
+GK+ +V
Sbjct: 11439 EVTGKWVRV 11447
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 16235 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16291
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 16292 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16351
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16411
Query: 1341 YGTSEPSQESELTTVGE--KPEEPK 1363
YG EP + + P+ PK
Sbjct: 16412 YGVGEPLESEPVVAKNPFVVPDAPK 16436
Score = 101 bits (251), Expect = 7e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1174 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1233
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 22058 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22115
Query: 1234 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1293
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 22116 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22174
Query: 1294 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1352
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 22175 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22234
Query: 1353 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1402
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22293
Query: 1403 SGKFGQVFRLVEK 1415
V RLVEK
Sbjct: 22294 KQLTFTVERLVEK 22306
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 15160 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15219
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 15220 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15279
Query: 1292 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 15280 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15339
Query: 1351 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1402
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 15340 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15389
Query: 1403 SGKFGQVFRLVEKKT 1417
K GQ + KKT
Sbjct: 15390 -DKAGQRWIKCNKKT 15403
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 15854 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15913
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 15914 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15973
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 15974 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 16019
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 554
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362
Query: 555 -------------------------------------------------IFLQGLSDLKV 565
+F+ K
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 684 HWLRD 688
WL++
Sbjct: 1542 VWLKN 1546
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1219
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 9811 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9869
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1279
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 9870 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9929
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1338
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 9930 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9989
Query: 1339 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 9990 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 10038
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 17318 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17374
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1282
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 17375 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17434
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1341
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 17435 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17494
Query: 1342 GTSEPSQES 1350
G EP + +
Sbjct: 17495 GVGEPLESA 17503
Score = 99.0 bits (245), Expect = 4e-20
Identities = 98/385 (25%), Positives = 150/385 (38%), Gaps = 54/385 (14%)
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
R SP + + P E E+ A L TSS A ++ +AP
Sbjct: 764 RTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSS-----AQKITKSVKAP-- 816
Query: 362 GVLSPSGEERKRPAPPRPATFP------TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
+ PS E R R P FP T + G + V K I R+ F
Sbjct: 817 -TVKPS-ETRVRAEPTPLPQFPFADTPDTYKSEAGVE--VKKEVGVSITGTTVREERFEV 872
Query: 416 FESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 475
+ E K +T + + + P+ S LK+ VIEG+ L+C + G P P
Sbjct: 873 LHGR----EAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 927
Query: 476 ITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
+TW I+ + + T ++G+A L I++A ED G +TC A N G VS S ++ V
Sbjct: 928 VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Query: 533 -----EKKSSRKSEYLLP----------------------VAPSKPTAPIFLQGLSDLKV 565
EK+++ +E P +P AP F+ K+
Sbjct: 988 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKL 1047
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQRGTQHSLCIQEVFPEDTGT 623
++G V QV GNP P V W +G + + + ++ + L I F +D G
Sbjct: 1048 VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHD 648
YT N GE A L + ++
Sbjct: 1108 YTIVVRNKHGETSASASLLEEADYE 1132
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 21270 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21329
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 21330 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21389
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21390 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21437
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13120
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 13121 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13168
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1159 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1277
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1336
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 10623 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10682
Query: 1337 AINVYGTSEPSQESELTT-----VGEKPEEP 1362
A N+YG S+P + V + P++P
Sbjct: 10683 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10713
Score = 95.9 bits (237), Expect = 3e-19
Identities = 158/697 (22%), Positives = 252/697 (36%), Gaps = 128/697 (18%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ-MGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN-VKTTAKLIVEG---AVVE 2222
Query: 260 FVRETKATN--SDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAP---GLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423
G+E QP V+ K ++ + + ++ A
Sbjct: 2342 WMKDGQEV--------------QPSDRVHIVIDKQSHMLLIEDMTKEDA----------- 2376
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFS----SVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 479
N + GL+ +S + LKD VIEG VL+C V V + W
Sbjct: 2377 ---GNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWY 2433
Query: 480 LNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
LN + I+ ++ + L I D G Y + +G+V + ++V + K
Sbjct: 2434 LNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLI----VGRVETNCNLSVEKIK- 2488
Query: 537 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
++GL DL + V V++S + +V+W EI+
Sbjct: 2489 -------------------IIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKP 2528
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
S + E G + L + + +D G YT AGE T LTV IS
Sbjct: 2529 SSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAGENMTSGKLTV-------AGGAIS 2577
Query: 657 KP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
KP T + Q + C +A +P WLRDGK L
Sbjct: 2578 KPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHL 2613
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+G + + + K P P I D V GE + + T +W K
Sbjct: 8061 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8177
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1323
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 8178 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8236
Query: 1324 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1380
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 8237 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8295
Query: 1381 RTVTINTEQKVSDFYDIEERLGSGK 1405
+ + K+ + I E++ G+
Sbjct: 8296 KPPLYDGGSKIMGY--IIEKIAKGE 8318
Score = 95.9 bits (237), Expect = 3e-19
Identities = 64/229 (27%), Positives = 117/229 (51%), Gaps = 20/229 (8%)
Query: 531 VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 588
VHE+ K+S+ SE + A K + + + + +G ++ + ++G +V W+
Sbjct: 26716 VHEEITKTSQASEEVRTHAEIKAFS-------TQMSINEGQRLVLKANIAG--ATDVKWV 26766
Query: 589 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
NG E+ SE++ + G+ +L I++ D G TC + G V+ Q LT+ +
Sbjct: 26767 LNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS 26826
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
P FIS+PRS + GQ+VL +C I+G+P P + W ++ + + + + ++ +V+
Sbjct: 26827 DA-PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVY 26884
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757
+L ++ +G+Y I KN G+CS SLM+ LP EP+
Sbjct: 26885 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-------LPLVEEPS 26926
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1180 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 14085 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14144
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 14145 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14203
Query: 1299 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 14204 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14260
Query: 1355 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 14261 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14293
Score = 95.5 bits (236), Expect = 4e-19
Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 29/293 (9%)
Query: 475 RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++TW + ++ + T E GVA L+++D D GTY C N G+ S A + V
Sbjct: 25294 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Query: 532 HE-------------KKSSRKSEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 577
KK R+++ + L P + T P++ + G V V +
Sbjct: 25354 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTI 25408
Query: 578 SGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ +P P V W +G +I+ ++ + FE + L I V +D YT A N GE
Sbjct: 25409 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25468
Query: 635 VRTQAVLTVQ---EPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
+A LTV P D T +P F + GQSV ++G P PT+ W +DG+
Sbjct: 25469 DSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 25528
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
L + + D + L ++ P G Y + N G SCQ L ++
Sbjct: 25529 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 14483 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14540
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 14541 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14599
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 14600 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14659
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1409
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 14660 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14709
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 19481 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19537
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 19538 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19597
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 19598 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19657
Query: 1341 YGTSEP 1346
YG EP
Sbjct: 19658 YGVGEP 19663
Score = 94.7 bits (234), Expect = 7e-19
Identities = 131/586 (22%), Positives = 204/586 (34%), Gaps = 111/586 (18%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26128
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN----------------------- 257
+ DD G Y + N G+AS A L + G D
Sbjct: 26129 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26188
Query: 258 --------------RSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQR 302
S VRE K+ ++ R+ +++ S +++ S KS S R
Sbjct: 26189 YAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTR 26248
Query: 303 GGSPPWAANSQPQPPR------ESKLESCKDSPRTAPQTPVLQK--------------TS 342
AA +P ES SC P L+K T
Sbjct: 26249 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 26308
Query: 343 SSITLQAARVQPEPRAPGLGVLSPS-GEE--------RKRPAPPRPATFPTR----QPGL 389
T + + VQ V+ S G++ +K + T P R +P +
Sbjct: 26309 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRV 26368
Query: 390 GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSS 449
S + V + P E A E+KP E ++ V P +
Sbjct: 26369 KSPEAVKSPKRVKSP-EPSHPKAVSPTETKPTPTEKVQHLPVS----------APPKITQ 26417
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEAGVAELHIQD 503
LK A + L C V + + +TW +G+ ++ + G EL I +
Sbjct: 26418 FLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINN 26475
Query: 504 ALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKSEYLLPVAPS 549
D G Y C G Q A+ ++HEK KS +K+ +
Sbjct: 26476 LTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT 26535
Query: 550 KPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
+P AP + + GL D V S V+ +G P P IW +G I + +
Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
+ L I + D+G YTC NSAG V + LT++ D
Sbjct: 26596 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26641
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 23153 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23210
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 23211 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23269
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 23270 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23329
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P P ++EV D V TVT+ E+ + D
Sbjct: 23330 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23356
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 19101 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19160
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 19161 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19219
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 19220 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19277
Query: 1359 PEEP 1362
P P
Sbjct: 19278 PFSP 19281
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1181 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1232
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 9518 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9577
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9636
Query: 1293 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 9637 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9696
Query: 1352 LTTVGEK--PEEPKDEVEV 1368
TT + P +P ++++
Sbjct: 9697 RTTARDPIYPPDPPIKLKI 9715
Score = 92.4 bits (228), Expect = 3e-18
Identities = 177/792 (22%), Positives = 297/792 (37%), Gaps = 139/792 (17%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSL 288
G YT + +G +A+L ++G D RS ++KEV VI K+ +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRS-----------IKKEV-QVIEKQRAVVEF 3122
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR----TAPQTPVLQKTSSS 344
E + + G + + + E ++ S T V + SS
Sbjct: 3123 EVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSS 3182
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG---SQDVVSKAANR 401
+TL +P P+ L L P + +PA QP + + ++S
Sbjct: 3183 VTLYVNAPEP-PQV--LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239
Query: 402 RIPMEGQRDS-----AFPKFESKPQSQEVKENQTVKFRCEGLAVM--EVA---------- 444
+ +GQ + AFP+ ++ + E K + V L+V EV
Sbjct: 3240 KFLHDGQEYTLLLIEAFPE-DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3298
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHI 501
P+ + L+D EGQ QC V GT + +++W + P ++ R T +L I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEK--------KSSRKSEYLLPVAPSKPTA 553
+A PED GTYT +A NA+GQVS +A +++ + K R+S VA S T
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTK 3417
Query: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
++K GS VQV + I H +Q+++ H+ +
Sbjct: 3418 EESKISQKEIKSFQGSSYEYEVQVFESVSQSSI--HTAASVQDTQ--------LCHTASL 3467
Query: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 673
++ + C A S GE P + VT G + C
Sbjct: 3468 SQIAESTELSKEC-AKESTGEA----------------PKIFLHLQDVTVKCGDTAQFLC 3510
Query: 674 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
+ D F V W +G A +++ + QN ++ L + VQ G Y ++ N GE
Sbjct: 3511 VLKDDSFIDVTWTHEG-AKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGE 3569
Query: 734 CSCQVSLMLQNS 745
+ L ++ +
Sbjct: 3570 RTTSAVLSVEGA 3581
Score = 92.4 bits (228), Expect = 3e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1221
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 18400 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18456
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 18457 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18516
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 18517 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18576
Query: 1341 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1369
YG EP + +T KP P EVS
Sbjct: 18577 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18606
Score = 92.4 bits (228), Expect = 3e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 23418 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23471
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 23472 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23531
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1325
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 23532 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23591
Query: 1326 LPDHEYKFRVRAINVYG 1342
+EY FRV A N +G
Sbjct: 23592 TEGNEYVFRVAATNRFG 23608
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 20979 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 21038
Query: 1241 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 21039 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21157
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1405
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 21158 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21201
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 16996 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 17055
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 17056 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1232
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 9104 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9163
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 9164 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9222
Query: 1293 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1349
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 9223 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9282
Query: 1350 SEL 1352
++
Sbjct: 9283 DKV 9285
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1157 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1213
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 10899 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10958
Query: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1273
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 10959 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 11015
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1332
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 11016 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11075
Query: 1333 FRVRAINVYG 1342
FRV A N YG
Sbjct: 11076 FRVAAENQYG 11085
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1163 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 15544 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15601
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 15602 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15660
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 15661 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15720
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A N YG P++ +E E+P P
Sbjct: 15721 LAENEYGIGLPAETAESVKASERPLPP 15747
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1180 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10287
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10346
Query: 1298 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 10347 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10406
Query: 1357 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1406
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 10407 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10458
Query: 1407 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1455
K T + + KE + +S +N + K C
Sbjct: 10459 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10500
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16706
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 16707 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16765
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 16766 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16825
Query: 1359 PEEP 1362
P+ P
Sbjct: 16826 PQPP 16829
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1159 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1209
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 23813 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23872
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 23873 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23930
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1328
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 23931 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23990
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1385
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 23991 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 24050
Query: 1386 NTEQKVSDFY 1395
+ +V+ +Y
Sbjct: 24051 DGGSRVTGYY 24060
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 610
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 731 VGECSCQVSLMLQ 743
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.4 bits (220), Expect = 3e-17
Identities = 60/221 (27%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS 490
+K R + + ++E P F+ L + G++ ++ P P +TW +GQ I+ +
Sbjct: 25371 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 25430
Query: 491 ------TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 544
+ G+ +L I +D YT +A N G+ SC A +TV L
Sbjct: 25431 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV----------TLH 25480
Query: 545 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604
P P+F + L++ + +G V ++VSG PPP + W +G + +
Sbjct: 25481 PPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH 25540
Query: 605 RGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
G ++L I++ PEDTG Y A N+AG QA L V+
Sbjct: 25541 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581
Score = 87.8 bits (216), Expect = 9e-17
Identities = 144/684 (21%), Positives = 237/684 (34%), Gaps = 121/684 (17%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIH 221
F +++ + EG F CK++G P P++ W K ++ R + ++G L I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISK 281
V +D G+YT N G A S +L ++ T S +R +S+
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
+ A S SP R + + + ES+LE R VL+
Sbjct: 1367 SP--IRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLE------RLYKPVFVLKPV 1418
Query: 342 S-SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAAN 400
S + Q AR + K P P TF Q +V+ +
Sbjct: 1419 SFKCLEGQTARF-----------------DLKVVGRPMPETFWFHD----GQQIVNDYTH 1457
Query: 401 RRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEGLAVME-----VAPSFSSVLK 452
+ + E S + S E V +N+ + + +E V P F LK
Sbjct: 1458 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLK 1517
Query: 453 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPE 507
+ + EG ++ G P P I WL N P +Y + E G A L I + +
Sbjct: 1518 NVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQ 1577
Query: 508 DHGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP-------- 548
D YT A N G+ C V V + + + ++P AP
Sbjct: 1578 DSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLR 1637
Query: 549 --------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGN 592
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1638 YGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGK 1697
Query: 593 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE------- 645
++ + SL + D+G TC A N G T A L V++
Sbjct: 1698 PLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757
Query: 646 -------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCA 674
H+G +P + P V G++ C
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
+ G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1818 VTGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVI 1875
Query: 735 SCQVSLMLQNSS--ARALPRGREP 756
+V L +Q L R EP
Sbjct: 1876 EHKVKLEIQQREDFRSVLRRAPEP 1899
Score = 87.8 bits (216), Expect = 9e-17
Identities = 74/292 (25%), Positives = 123/292 (42%), Gaps = 42/292 (14%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376
Query: 240 GKASMSAELS--IQGLDSAN-----RSFVRETKATNSDVRKEVTNVISKESK 284
G+ S +A LS +Q LD + R + +S KE + + KE K
Sbjct: 3377 GQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKISQKEIK 3428
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1163 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1216
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 12292 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12348
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12407
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 12408 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12467
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A+N YG P+ + + EP
Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEP 12494
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 13370 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13429
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 13430 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13488
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1328
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 13489 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13548
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1359
Y FRV A N YG +P + + + P
Sbjct: 13549 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13579
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1168 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 18799 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18856
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 18857 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18915
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 18916 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Query: 1344 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P++ +E V E P P V +V T TI E+ SD
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 19017
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 17731 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17788
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 17789 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17847
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 17848 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17907
Query: 1359 PEEP 1362
P P
Sbjct: 17908 PSPP 17911
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 18078 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18137
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 18138 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18185
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/238 (28%), Positives = 104/238 (43%), Gaps = 21/238 (8%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG- 77
V P++ DS P FI N I G A V G P+P++ W NG +T
Sbjct: 3635 VYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD 3694
Query: 78 -RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVV 136
+F+ D SL+I ED G+YTC A+N G T+ ++ K +
Sbjct: 3695 YKFVFD---GDDHSLIILFTKLEDEGEYTCMASNDYGK-------TICSAYLK-----IN 3739
Query: 137 SKTLGDRFS---APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT 193
SK G + + + ++ + G CPP F +L + +G F + G P P VT
Sbjct: 3740 SKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3799
Query: 194 WLKGNVPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
W K N L S + + NG ++ ++D G+Y C N G+++ +AEL +
Sbjct: 3800 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 85.1 bits (209), Expect = 6e-16
Identities = 178/820 (21%), Positives = 302/820 (36%), Gaps = 113/820 (13%)
Query: 367 SGEERKRPAPP--RPATFPTRQPGLGSQDVVSKAANRR-IPMEGQRDSAFPKFESKPQSQ 423
SG+ PA P P PT +P + + ++ +R I M R S ++
Sbjct: 1330 SGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPA 1389
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
+ + ++ E P F +EGQ V G P+P W +GQ
Sbjct: 1390 RMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQ 1449
Query: 484 PI--QYARSTC--EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 539
I Y E G L I A P D G +T +A+N G+ S S +TV + K
Sbjct: 1450 QIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1509
Query: 540 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
P+F++ L ++ + +GS++ M V+ +GNP P+++WL N + I +
Sbjct: 1510 --------------PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1555
Query: 600 FHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 657
GT + +L I +D+ YT A N AG T+ + V+ +P
Sbjct: 1556 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEP----- 1610
Query: 658 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF------TLV 711
R + G + IA +H LR G+ ++ ++ + + F +L
Sbjct: 1611 ERKLIIPRG--TYRAKEIAAPELEPLH-LRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR 1667
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR---EPASCEDLCGGGVG 768
LK+ P H +E L +G+ + V + A R R E C G
Sbjct: 1668 LKRFGPAH---FECRL-TPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1723
Query: 769 ADGG-----GSDRYGSLRPGWP--ARGQGWLEEED--GEDVRGVLKRRVETRQHTEEAIR 819
D G +++YG+ + + L EE E +G+ + R E A+
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALT 1783
Query: 820 QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKT--------VSE 871
+Q + K+ L + ++ + E FR + +PK + +
Sbjct: 1784 GVTTDQKE------KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRK 1837
Query: 872 EER------KVHSPQQVDFRS--VLAKKGTSKTP---VPEKVPPPKPATPDFRSVLGGKK 920
+R +H VD +S K T++ P + KV DFRSVL
Sbjct: 1838 SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1897
Query: 921 KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 980
+ E L + + +P+ + K V K AE + + +E L+
Sbjct: 1898 EPRPEFHVHEPGKLQFEVQKVDRPVDTTE----TKEVVKLKRAERITHEKVPEESEELRS 1953
Query: 981 MGNAKPDE---------NLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQG 1026
+ +E LKS K+E +++ + H T+ EK++ E +
Sbjct: 1954 KFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKI 2013
Query: 1027 TAPAFK----------------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTL 1069
T P FK +++Q V +G + +V P W NG K
Sbjct: 2014 TIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE 2073
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
++ + E ++C + I ED A N AG+
Sbjct: 2074 RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2113
Score = 84.7 bits (208), Expect = 7e-16
Identities = 150/724 (20%), Positives = 239/724 (33%), Gaps = 89/724 (12%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438
T PT +P +I + ++ PK + QSQ V + FR
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVR-- 2054
Query: 439 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC----EA 494
V G P P W NG I+ + E
Sbjct: 2055 -----------------------------VVGKPDPECEWYKNGVKIERSDRIYWYWPED 2085
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
V EL I+D ED + A N G+ S A++ V K+
Sbjct: 2086 NVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ-----------------LI 2128
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F Q L D+ + + + P +V W +G E+ E + + H L I
Sbjct: 2129 TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSIL 2188
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ D Y+C V+T A L V +G F+ + + + S + C
Sbjct: 2189 TIDTSDAEDYSCVLVEDE-NVKTTAKLIV----EGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ + W + L K G + + L +K V G+Y ++ + C
Sbjct: 2244 VSPENIEG-KWYHNDVEL-KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2301
Query: 735 SCQV 738
++
Sbjct: 2302 KLKM 2305
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 13701 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 13761 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13820
Query: 1312 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
A+ + T+F V L EY FRV A N YG E
Sbjct: 13821 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13855
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1168 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 20168 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20227
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 20228 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20287
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 20288 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20347
Query: 1344 SE 1345
S+
Sbjct: 20348 SD 20349
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1169 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 21650 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21709
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 21710 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21769
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 21770 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21829
Query: 1344 SEP 1346
P
Sbjct: 21830 GRP 21832
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 813 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 869
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726
Query: 870 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 928
SE K + + S + K T V P+ A+P F K +P
Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783
Query: 929 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 986
A + K LS + + + + A T+KP AE L A
Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840
Query: 987 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1026
+ KS + E+KK+V + GTT E+R E
Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894
Query: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1086
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071
Query: 1205 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1017 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 6682 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6741
Query: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 6742 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6786
Query: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
PV E T + + ++ + G S ++ G V
Sbjct: 6787 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6823
Query: 1196 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1253
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 6824 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6883
Query: 1254 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 6884 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6936
Query: 1314 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 6937 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6996
Query: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1424
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 6997 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 7056
Query: 1425 FFKAYSAKEKENIRQEISIMNCL 1447
+ SA+ K + I+ L
Sbjct: 7057 YLYRVSAENKAGVSDPSEILGPL 7079
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 19893 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19950
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 19951 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 20009
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 20010 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20069
Query: 1359 PEEPK 1363
P P+
Sbjct: 20070 PSPPE 20074
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 24602 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24661
Query: 593 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 650
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 24662 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24721
Query: 651 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 710
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 24722 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24780
Query: 711 VLKK-VQPWHAGQYEILLKNRVG 732
V V+ AG Y + KNR G
Sbjct: 24781 VFPNGVERKDAGFYVVCAKNRFG 24803
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 25374 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25433
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 25434 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25486
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 25487 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 25588 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25619
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1237
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11967
Query: 1238 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 11968 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 12026
Query: 1298 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1354
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 12027 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12086
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1395
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 12087 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12126
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24344
Query: 673 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 731
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 24345 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24403
Query: 732 GECSCQVSLMLQN 744
G + + +Q+
Sbjct: 24404 GTVDAILDVEIQD 24416
Score = 81.6 bits (200), Expect = 6e-15
Identities = 75/315 (23%), Positives = 116/315 (36%), Gaps = 74/315 (23%)
Query: 12 ISKTSLSVDPSRVD---SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
ISKT + + D S L++APAFI PR+ I EG F + G P P++ W +
Sbjct: 26805 ISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 26864
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL------- 121
N PI+ + R +SL I D GKYT +A N G T L
Sbjct: 26865 NNLPISISSNVSISRS-RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923
Query: 122 --------------TVEGSFAKQLGQPVVSKTLGD---------------RFSAPAVETR 152
+++GSF+ Q Q SK +F++ + ++
Sbjct: 26924 EPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSM 26983
Query: 153 PSIWGE--------------------------------CPPKFATKLGRVVVKEGQMGRF 180
S+ PPK + + EG++
Sbjct: 26984 SSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTV 27043
Query: 181 SCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
+C TG P P+VTW G + Q R + + + L I V + D G+YT + N
Sbjct: 27044 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 27103
Query: 239 SGKASMSAELSIQGL 253
G S + + I+ +
Sbjct: 27104 FGSDSATVNIHIRSI 27118
Score = 81.3 bits (199), Expect = 8e-15
Identities = 123/536 (22%), Positives = 192/536 (35%), Gaps = 142/536 (26%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 26713 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26763
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 26764 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26821
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 26822 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26851
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 26852 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26911
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 26912 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26954
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 26955 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26999
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 27000 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 27031
Query: 422 SQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481
+ E + V+ VA C+ G P P +TW
Sbjct: 27032 DISIDEGK----------VLTVA---------------------CAFTGEPTPEVTWSCG 27060
Query: 482 GQPI---QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
G+ I + R E + L I D +D G YT N G S SA V +H
Sbjct: 27061 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG--SDSATVNIH 27114
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 22738 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22854
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 22855 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22914
Query: 1341 YG-----TSEPSQESELTTVGEKPEEPKD 1364
YG SEP T+ P P++
Sbjct: 22915 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22943
Score = 80.1 bits (196), Expect = 2e-14
Identities = 170/794 (21%), Positives = 285/794 (35%), Gaps = 143/794 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 5513 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5563
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 5564 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5622
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 5623 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5682
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 5683 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5742
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V W K ++PS + ++L + + D+G YTC G S +L I
Sbjct: 5743 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5797
Query: 251 QGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAA 310
+ +R + +V + T E D + A K K + Q
Sbjct: 5798 E-----DREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQ--------- 5843
Query: 311 NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEE 370
+ E K+ S QT + ++++ +A ++ +PR +G+L P +
Sbjct: 5844 TPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVK-SSAHLRVKPRV--IGLLRPLKDV 5900
Query: 371 RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
ATF L +D+ + + +E D P+ E K + +++
Sbjct: 5901 TVTAG--ETATFDCE---LSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRD--- 5951
Query: 431 VKFRCEG--------------LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 476
VK G L V E F+ L+D V EG VL+C V ++
Sbjct: 5952 VKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKV 6010
Query: 477 TWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
W NG I ++ + V +L I D PED TYTC A++ + SC+ V
Sbjct: 6011 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 6065
Query: 534 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
P FL+ L+DL+V + ++S +V W +G E
Sbjct: 6066 -----------------PPHVEFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAE 6107
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPW 653
I++ + + +G L I + +D Y+CE + RT +LTV E +
Sbjct: 6108 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLE----EEAV 6159
Query: 654 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 713
F ++ S ++ + C ++ P V W + + + +TG +E+L LV++
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEII-ETGRYEILTEGRKRILVIQ 6217
Query: 714 KVQPWHAGQYEILL 727
AG Y L
Sbjct: 6218 NAHLEDAGNYNCRL 6231
Score = 80.1 bits (196), Expect = 2e-14
Identities = 181/813 (22%), Positives = 280/813 (34%), Gaps = 141/813 (17%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 26065 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26123
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 26124 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26183
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 26184 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26242
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 26243 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26302
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 26303 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26355
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 26356 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26406
Query: 328 SPRTAPQ--TPVLQ-KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAP-----PRP 379
P +AP T L+ + S I V+ G++ K
Sbjct: 26407 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26466
Query: 380 ATFPTRQPGLGSQDV---------VSKAANRRIPMEGQRDSAFPKFESK----PQSQEVK 426
T+ + L D + + GQ + + SK +S +
Sbjct: 26467 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26526
Query: 427 ENQTVKFRCEGLAVMEVA--PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRIT--WLLNG 482
TV + E A ++ P + L+D V D V + +V+ T PR T W +G
Sbjct: 26527 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTV--SSDSVAKFAVKATGEPRPTAIWTKDG 26584
Query: 483 QPI----QYARSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 537
+ I +Y S + G E+H D D G YTC +N+ G VS S +T+ K +
Sbjct: 26585 KAITQGGKYKLSEDKGGFFLEIHKTDT--SDSGLYTCTVKNSAGSVSSSCKLTIKAIKDT 26642
Query: 538 RKSEY-LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
+ + P +Q K + ++ M+ ++ +++
Sbjct: 26643 EAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS---EAKSQEKLALKEEASKVLI 26699
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
SE+ ++ SL V E T T ++ EVRT A + S
Sbjct: 26700 SEEV---KKSAATSLEKSIVHEEITKTS-----QASEEVRTHAEIKA-----------FS 26740
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
S+ GQ +++ IAG V W+ +G L + + D TL +K+
Sbjct: 26741 TQMSINE--GQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQ-TLTIKQAS 26795
Query: 717 PWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 749
G + K + G CQ L L + A
Sbjct: 26796 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDA 26828
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 14773 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14832
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 14833 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14892
Query: 1301 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1342
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 14893 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14935
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1669 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1728
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 1729 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 79.0 bits (193), Expect = 4e-14
Identities = 148/719 (20%), Positives = 276/719 (38%), Gaps = 111/719 (15%)
Query: 35 FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVI 93
F+ P +L ++E A+FE + +V W ++G I G ++ D +G LVI
Sbjct: 6071 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVI 6127
Query: 94 HAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRP 153
+ +D +Y+CE + +TV L E F K L VS+T
Sbjct: 6128 NKCLLDDEAEYSCEVRTARTSGMLTV-LEEEAVFTKNLANIEVSET-------------- 6172
Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
+ C+++ +P +V W KG+ + + R + +
Sbjct: 6173 ----------------------DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEG 6209
Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNG--SGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
++L I + +D G Y C + + GK + EL+ + + + E +
Sbjct: 6210 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAEFISKPQNLEILEGE------ 6262
Query: 272 RKEVTNVISKES-----KLD--SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324
+ E ISKES K D +LE+ K + ++ A Q + +
Sbjct: 6263 KAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGA 6322
Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384
R A V++K + L+ RV+ + ++ G + K A F +
Sbjct: 6323 A----RAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKW-FRNEEAIFDS 6377
Query: 385 RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVA 444
+ + +D+V R ++ Q + + + + + VK + E L ++E
Sbjct: 6378 SKYIILQKDLVYTLRIRDAHLDDQAN--YNVSLTNHRGENVKSAANLIVEEEDLRIVEP- 6434
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---I 501
LKD +E + C V V + W NG+ + + H I
Sbjct: 6435 ------LKDIETMEKKSVTFWCKVNRLNVT-LKWTKNGEEVPFDNRVSYRVDKYKHMLTI 6487
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+D D G Y VT + KS +E L+ AP++ F++ L
Sbjct: 6488 KDCGFPDEGEYI---------------VTAGQDKSV--AELLIIEAPTE-----FVEHLE 6525
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D V + + Q+S V W NG EI+E + + FE+ G+ H L I++ +D
Sbjct: 6526 DQTVTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDE 6584
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE-PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Y C + +++A L V+E P + +P P+ + + G V+ + D
Sbjct: 6585 CEYAC----GVEDRKSRARLFVEEIPVEIIRP-----PQDILEAPGADVVFLAELNKDKV 6635
Query: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
V WLR+ + + H +++ + L + ++P G+Y + K++ +++
Sbjct: 6636 -EVQWLRNNMVVVQGDKH-QMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELA 6692
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1156 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1207
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 8359 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8416
Query: 1208 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1241
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 8417 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8476
Query: 1242 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1301
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 8477 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8535
Query: 1302 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 8536 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8593
Query: 1359 PEEPKD 1364
P P D
Sbjct: 8594 PFGPPD 8599
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1159 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 7078 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7137
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 7138 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7196
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1335
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 7197 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7256
Query: 1336 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1364
A N G EP+ E ++T P+ P++
Sbjct: 7257 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7288
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 22241 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22300
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22332
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+K+ T + Q+I +AG + ++G TW +
Sbjct: 22333 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22382
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1268
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 22383 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22442
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1327
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 22443 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
EY FRV + N +G S+P + + + + E P P
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22535
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 16925 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16984
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y N GQ S ++ D P + K P
Sbjct: 16985 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 17027
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
D + + PP QI + ++ T W
Sbjct: 17028 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17071
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1263
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 17072 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17119
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1316
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 17120 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17173
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 17174 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17219
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 6520 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6578
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1137
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 6579 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6638
Query: 1138 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1172
++++ V G + + K + + A P+I
Sbjct: 6639 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6698
Query: 1173 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1232
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 6699 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6755
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 6756 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6814
Query: 1293 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1349
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 6815 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6873
Query: 1350 SELTTVGEKPEEPKDEVEVSDDD 1372
K + P + V+ D
Sbjct: 6874 DNPVEARSKYDVPGPPLNVTITD 6896
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1652 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1710
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 1771 ATCTAELIVETMEEGEGE 1788
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
K P+ L D +G V +T ++ EV W + E F Q +
Sbjct: 4431 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4488
Query: 610 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 668
+L I +V ED G Y CEA N +G+ T A LTV + P K + +LG
Sbjct: 4489 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4545
Query: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 728
+C I P W + G+ + ++ + ++ + +L + + Q G+Y
Sbjct: 4546 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4604
Query: 729 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 784
N G SC +L + R L R+P E++ S+
Sbjct: 4605 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4651
Query: 785 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 844
P + +E + E V K+ + + + EV + R+ +K+ T +
Sbjct: 4652 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4704
Query: 845 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 901
IP + + + +V KP V E + +P V V+ KK +K P E
Sbjct: 4705 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4761
Query: 902 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 958
P P + G KK P+ + + E P + + PLK V
Sbjct: 4762 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4814
Query: 959 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1004
K + +G++ E L A K N++ + K D K+
Sbjct: 4815 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4874
Query: 1005 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1055
+ C + G+ T K + K ++V V +G+ L L C+++ +
Sbjct: 4875 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4934
Query: 1056 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1114
++W +GK ++ I+ G + +++I A D G Y +N A ECS
Sbjct: 4935 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4991
Query: 1115 QVTV 1118
V V
Sbjct: 4992 CVKV 4995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 983 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1036
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 8030 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8089
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 8090 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8149
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1156
G+Y +N G A S V V P ++K+ SD T
Sbjct: 8150 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8191
Query: 1157 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PP+ G PI ++ R++ ++
Sbjct: 8192 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8223
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1274
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 8224 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8283
Query: 1275 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1326
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 8284 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8340
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1373
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 8341 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8391
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1155
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 20241 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20286
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 20287 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20336
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1275
+EN + + + S V L P PP+ TP +++
Sbjct: 20337 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20377
Query: 1276 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1333
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 20378 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20437
Query: 1334 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 20438 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20496
Query: 1394 FYDIEER 1400
Y +E R
Sbjct: 20497 -YIVERR 20502
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLV 3857
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1259
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 23962 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 24021
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1317
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 24022 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24081
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1368
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 24082 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24134
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 8793 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8848
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1278
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 8849 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8908
Query: 1279 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1338
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 8909 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8967
Query: 1339 NVYGTSEPSQESELTTV 1355
N +G P + + V
Sbjct: 8968 NKFGCGPPVEIGPILAV 8984
Score = 71.6 bits (174), Expect = 6e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 20859 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20917
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 20918 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20971
Score = 71.2 bits (173), Expect = 8e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1255
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 7619 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7667
Query: 1256 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 7668 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7727
Query: 1312 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1368
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 7728 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7787
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
SE +GT P F +++ + ++ G L V P I W NG L + +G
Sbjct: 3642 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3701
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
S+ I ED G Y C+A ND G+ CS + + N+K K
Sbjct: 3702 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3747
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
TE+++ V K P PP ++ + + G V G T T
Sbjct: 3748 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3799
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+
Sbjct: 3800 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3859
Query: 1261 KPDPPAGTPC 1270
+ TPC
Sbjct: 3860 EDTDMTDTPC 3869
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21327
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y + N C++ V P + T P K + P
Sbjct: 21328 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21358
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1214
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 21359 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21400
Query: 1215 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1268
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 21401 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21457
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1326
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 21458 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21517
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1386
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 21518 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21569
Query: 1387 TEQKVSD------FYDIEERLGSGKF 1406
+ D Y IE+R G+ ++
Sbjct: 21570 WNPPLRDGGSKIVGYSIEKRQGNERW 21595
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 7392 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7451
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y A N G+A +V V D P PP +D T +
Sbjct: 7452 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7493
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
PP+ +I + +++ E W K ++++
Sbjct: 7494 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7537
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1270
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 7538 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7584
Query: 1271 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1327
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 7585 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7644
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 7645 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7679
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1746
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.3 bits (168), Expect = 3e-11
Identities = 153/729 (20%), Positives = 270/729 (37%), Gaps = 101/729 (13%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 497
L V E+ F+ LKD V E + +C + T + W I+ +
Sbjct: 5174 LTVKEIELDFAVPLKDVTVPERRQARFECVL--TREANVIWSKGPDIIKSSDKFDIIADG 5231
Query: 498 ELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
+ HI D+ +D G YT E + S +VT K
Sbjct: 5232 KKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGIRLK------------------- 5270
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F+ L D V +G T ++S + V+W N ++ S G H L ++
Sbjct: 5271 -FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMK 5328
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
EV +D + E+ + A L V E P+F K TA + + C
Sbjct: 5329 EVTLDDISQIKAQV----KELSSTAQLKVLE----ADPYFTVKLHDKTAVEKDEITLKCE 5380
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ D V W +DG+ + + + + L +KK G+Y C
Sbjct: 5381 VSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYV---------C 5428
Query: 735 SCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG---ADGGGSDRYGSLRPGWPARGQG 790
C N + A L + +P ++ G + D +G W +GQ
Sbjct: 5429 DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ----WKLKGQP 5484
Query: 791 WLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLS 842
D E + K + T + + +A + L ++L + LS
Sbjct: 5485 LTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKEL--PLIFITPLS 5542
Query: 843 EDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQV--DFRSVLAKKGTSKTPVPE 900
D+K ++ F + R+ PKT R + Q++ D R L K GT + V +
Sbjct: 5543 --DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQEITGDDRFELIKDGTKHSMVIK 5594
Query: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
A F + + +G E + K + K ++ + + V +
Sbjct: 5595 SAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS 5648
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
+K N + T + + + + + S + ++L D + + + G + K
Sbjct: 5649 HDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDLSIDDTSQIRVEA--MGMSSEAK 5705
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
+ +G P F KLQD E +++LQC++S A + W +GK +K +K ++ +
Sbjct: 5706 LTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVIKAD 5763
Query: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
G + ++KAL D G Y C D G + S ++ ++D E+K RP S
Sbjct: 5764 GKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR---------EIKLVRPLHS 5810
Query: 1141 LPPVLGTES 1149
+ V+ TE+
Sbjct: 5811 V-EVMETET 5818
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1148 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1202
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 17105 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17164
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
K K I K +N E G + + + EN +G +A N
Sbjct: 17165 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17213
Query: 1263 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1318
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 17214 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17273
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1369
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 17274 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17333
Query: 1370 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1426
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 17334 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17393
Query: 1427 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1485
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 17394 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17453
Query: 1486 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1529
E + E + +++ EG EY+ + IM VNK G
Sbjct: 17454 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17495
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1288
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 19745 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19804
Query: 1289 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 19805 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19864
Query: 1348 QESELTTVGEKPEEPKDEVE 1367
S+ E+ EEP +++
Sbjct: 19865 DSSDPQIAKEREEEPLFDID 19884
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 11896 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11955
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1144
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 11956 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 12007
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
TV P P+ + I++ E +++ W
Sbjct: 12008 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 12040
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1261
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 12041 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12088
Query: 1262 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 12089 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12144
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 12145 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12191
Score = 68.6 bits (166), Expect = 5e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19149
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++A ED G Y+ N AG + V D P PP
Sbjct: 19150 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19191
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+ + PP+ QI + ++K + + TW +
Sbjct: 19192 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19235
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1264
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 19236 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19283
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1317
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 19284 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19338
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1377
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 19339 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19397
Query: 1378 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1406
+ + + K++ + L G++
Sbjct: 19398 LKWSKPHYDGGAKITGYIVERRELPDGRW 19426
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 26822 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26881
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1125
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 26882 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26941
Query: 1126 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1166
++++ +M + + ++S + + + + K A + +
Sbjct: 26942 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 27001
Query: 1167 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
+PP+I P D + G+ + + TG TW
Sbjct: 27002 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 27061
Query: 1207 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 27062 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 68.2 bits (165), Expect = 7e-11
Identities = 86/356 (24%), Positives = 138/356 (38%), Gaps = 82/356 (23%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1085
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP II +D G+ +V+GT + +W
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV-VDKPDP 1264
K+I+ S ++ E+ +L I A E G YT + N +G + NL++ V D
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDR 3394
Query: 1265 PAGTPCASDIRSSSLT--------------------LSWYGSSYDGGSAVQSYSIEIWDS 1304
+ D+R S+ + S+ GSSY+ Y +++++S
Sbjct: 3395 QSS---GKDVRESAKSQAVADSSFTKEESKISQKEIKSFQGSSYE-------YEVQVFES 3444
Query: 1305 ANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1360
++ + T+ +VQD H + ++E S+E + GE P+
Sbjct: 3445 VSQ------SSIHTAASVQDTQLCHTASLS----QIAESTELSKECAKESTGEAPK 3490
Score = 67.8 bits (164), Expect = 9e-11
Identities = 72/265 (27%), Positives = 99/265 (37%), Gaps = 26/265 (9%)
Query: 389 LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE--VKENQTVKFR-CEGLAVMEVAP 445
L + V A+ + E Q +S P E + S E +E TVK + EG + E P
Sbjct: 4376 LDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGP 4435
Query: 446 SFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQ 502
+ L D EG L S+ T + W + + + + + L I
Sbjct: 4436 MIHTPLVDTVSEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVID 4493
Query: 503 DALPEDH-GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
EDH G Y C A N G+ + SA +TV K AP+ + +
Sbjct: 4494 KVNTEDHQGEYVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIE 4536
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
L+V G T ++ P W G EI ES+ SL I D
Sbjct: 4537 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 4596
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEP 646
G YTC+A N G V A LTV P
Sbjct: 4597 GEYTCKASNEYGSVSCTATLTVTVP 4621
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1668 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 11212 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11271
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11319
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P P I E Q R + +G V+
Sbjct: 11320 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11350
Query: 1215 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1267
+GS T L GC + + ENK+G + V K P P G
Sbjct: 11351 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11403
Query: 1268 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1321
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 11404 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11458
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
V L + Y+FRV A N+ G S+PS S+
Sbjct: 11459 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11488
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 13002 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 13061
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1155
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 13062 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13121
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
K P A +V+ T PIT ++ K I+ E+
Sbjct: 13122 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13154
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1271
+ + ENK G + K DPP P
Sbjct: 13155 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13191
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 13192 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13251
Query: 1330 EYKFRVRAINVYGTSEPSQESE 1351
EY+FRV AIN G +PS S+
Sbjct: 13252 EYEFRVTAINKAGPGKPSDASK 13273
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1014 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1065
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 19859 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19918
Query: 1066 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 19919 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19974
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1185
PP T D T + A + + PE+
Sbjct: 19975 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19999
Query: 1186 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1243
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 20000 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 20048
Query: 1244 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 20049 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20107
Query: 1301 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1360
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 20108 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20167
Query: 1361 EPKDEVE 1367
P+ +++
Sbjct: 20168 PPEIDMK 20174
Score = 65.9 bits (159), Expect = 3e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8867
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y A N G + +V V D P P L PV+ T +
Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8913
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 8914 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8949
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1273
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 8950 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 9000
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1331
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 9001 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 9060
Query: 1332 KFRVRAINVYGTSEPS 1347
+FRV+A+N G SEPS
Sbjct: 9061 EFRVKAVNEIGESEPS 9076
Score = 65.9 bits (159), Expect = 3e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15230
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A N G A+ V V D P P V S+ V P
Sbjct: 15231 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15277
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I+Q E ++ W ++Q ++
Sbjct: 15278 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15308
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1277
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 15309 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15364
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 15365 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15424
Query: 1336 RAINVYGTSEPSQES 1350
A N G S PS S
Sbjct: 15425 MAENAAGISAPSPTS 15439
Score = 65.9 bits (159), Expect = 3e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 15711 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15769
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 15770 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15829
Query: 1349 ES 1350
S
Sbjct: 15830 LS 15831
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 23037 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23095
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 23096 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23149
Score = 65.5 bits (158), Expect = 5e-10
Identities = 84/382 (21%), Positives = 154/382 (40%), Gaps = 28/382 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 17729 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17786
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 17787 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17838
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDSPRTAPQTPVLQKTSSSI--- 345
AK KN +R + AN + + S K+E+ + + + +
Sbjct: 17839 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17897
Query: 346 TLQAARVQPEPRAPGLGVLSPSG--------EERKRPAPPRPATFPTRQPGLGSQ--DVV 395
T+ A + P PG L+ E+ + R + G++ +V
Sbjct: 17898 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17957
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
+++ + G +F K +++ K + V + + PS +
Sbjct: 17958 AESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS 18017
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALPEDHGTY 512
+ G+D ++ V G P P I+W+ +G+P+ Q R E A LHI++ +D G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077
Query: 513 TCLAENALGQVSCSAWVTVHEK 534
T A N+ G + + V V EK
Sbjct: 18078 TVTATNSAGTATENLSVIVLEK 18099
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 24621 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24680
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 24681 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24722
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 24723 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24771
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 24772 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24825
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 24826 SDVSRDSVNLTWTEPASD 24843
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 18007 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 18066
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y A N AG A + V V + P PPV
Sbjct: 18067 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18108
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D + PP QI + +++ T TW
Sbjct: 18109 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18152
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1262
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 18153 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18200
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1320
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 18201 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18259
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 18260 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18301
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 26233 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26291
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 26292 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26349
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 26350 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26409
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 26410 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26467
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 26468 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26527
Query: 275 VTNVISK 281
+ V K
Sbjct: 26528 ESTVTRK 26534
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 11615 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11674
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 11675 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11733
Query: 1300 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1356
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 11734 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11792
Query: 1357 -EKPEEPKD 1364
++P EP++
Sbjct: 11793 IDRPGEPEN 11801
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1146 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1200
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 13856 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13904
Query: 1201 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++F R + K K+T L E+ + ++ N G + +
Sbjct: 13905 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13962
Query: 1259 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 13963 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 14022
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1362
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 14023 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 16793 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16851
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 16852 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16909
Score = 63.5 bits (153), Expect = 2e-09
Identities = 95/427 (22%), Positives = 150/427 (35%), Gaps = 53/427 (12%)
Query: 1019 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS 1078
E ES G AP LQDV V G C + D + WT G ++ ++ + S
Sbjct: 3479 ECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQS 3538
Query: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEM 1132
Q G++ ++I D+GLY C+ ND G+ S ++V+ AP S E EM
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESILHERIEQEIEMEM 3598
Query: 1133 K----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPE 1176
K + S + L S++ V P K P I+
Sbjct: 3599 KEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVS 3656
Query: 1177 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHC 1236
+ + G+ L V G W + S K + L IL + E
Sbjct: 3657 NADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDE 3716
Query: 1237 GCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-------- 1288
G YT + N G L + K + T S + S L +
Sbjct: 3717 GEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPI 3776
Query: 1289 ---DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEY 1331
G A+ Y++ + TW K+L T S +F V D +
Sbjct: 3777 RCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSG 3836
Query: 1332 KFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINT 1387
+ +A N+ G S + E E T + + P + K E +D + P +++
Sbjct: 3837 LYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDS 3896
Query: 1388 EQKVSDF 1394
EQ+++ F
Sbjct: 3897 EQEIATF 3903
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1202
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 16024 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16082
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+K K K E G + + + G +G V P
Sbjct: 16083 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16133
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1320
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 16134 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16193
Query: 1321 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1363
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 16194 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16237
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20641
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G A + +V + D P P + T T+ +P P
Sbjct: 20642 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20688
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I++ E +V W SEH++ E
Sbjct: 20689 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20718
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 20719 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20775
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1335
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 20776 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835
Query: 1336 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1370
A+N G S+ SE + P P ++ ++D
Sbjct: 20836 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20872
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 63.2 bits (152), Expect = 2e-09
Identities = 71/301 (23%), Positives = 112/301 (37%), Gaps = 35/301 (11%)
Query: 3 DVKLVASSHISKTSLSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
D +L ++ +S+ + S + S+ + T EAP L +++ +K G TA+F ++
Sbjct: 3458 DTQLCHTASLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSF 3517
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
VTW G I R F L I V D+G Y+C N G R + L
Sbjct: 3518 IDVTWTHEGAKIEESERLKQSQNGNIQF-LTICNVQLVDQGLYSCIVHNDCGERTTSAVL 3576
Query: 122 TVEGS--------------------------------FAKQLGQPVVSKTLGDRFSAPAV 149
+VEG+ + +L +++TL +P
Sbjct: 3577 SVEGAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPVY 3636
Query: 150 ETRPSIWGE-CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
T+ E P F ++ + G + S + G P+P++ W V L PSA
Sbjct: 3637 PTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYK 3696
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L I +D G YTC+ N GK SA L I ++ E+
Sbjct: 3697 FVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAK 3756
Query: 269 S 269
S
Sbjct: 3757 S 3757
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1314
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 9399 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9458
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 9459 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9513
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1314
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 10805 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10863
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1363
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 10864 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10912
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 994
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 12483 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12533
Query: 995 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1035
+EE D + + + + G + +K E++G A +Q L
Sbjct: 12534 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12593
Query: 1036 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12653
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1146
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 12654 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12698
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
++DA P + + I+ E V G+ V VT T +
Sbjct: 12699 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12749
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
K I E++ +EN G L K+ AQ V +P
Sbjct: 12750 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12794
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1319
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 12795 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12845
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 12846 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12895
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25333
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 25334 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25387
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 25388 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25447
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 25448 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1017 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1074
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1134
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760
Query: 1135 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1194
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1195 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1254
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 1255 NLTVVDKPD 1263
L + + D
Sbjct: 1880 KLEIQQRED 1888
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1317
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 16532 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16590
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 16591 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16641
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 500
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 24227 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24286
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 559
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 24287 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24333
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 24334 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24389
Query: 620 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 24390 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24438
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1260
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 9951 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1314
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 10011 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10069
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 10070 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10117
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11716
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
+ P D G IT +++RK Q+ +
Sbjct: 11717 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11747
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1271
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 11748 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11805
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 11806 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11864
Query: 1330 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 11865 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11903
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1074
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1125
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1169
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1170 QI 1171
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1239 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1295
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 15026 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15084
Query: 1296 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1352
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 15085 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15144
Query: 1353 TTVGEKPEEPKDEVEVSDDD 1372
T + E PK +V+V D
Sbjct: 15145 ITCRDDVEAPKIKVDVKFKD 15164
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15902
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 15903 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15944
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D T PP K G S+ + V T TW
Sbjct: 15945 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15986
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1262
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 15987 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 16033
Query: 1263 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1318
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 16034 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16093
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 16094 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16152
Query: 1379 DYRTVTINTEQKVSDFYDIEERLGSGKF 1406
++ T + K++ + ++ L G++
Sbjct: 16153 QWKKPTYDGGSKITGYIVEKKELPEGRW 16180
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 16242 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16298
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16341
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1206
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 16342 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16391
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1261
KV G++ T + ++ NK G + + VV K
Sbjct: 16392 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16431
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1319
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 16432 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16490
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 16491 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16521
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W+K K + K + G + + + G +G V
Sbjct: 18246 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18296
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1319
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 18297 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18356
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 18357 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18405
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 21840 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21895
Query: 1312 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1366
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 21896 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21955
Query: 1367 EVSDDDEKEPEVDY 1380
+V+D + +++
Sbjct: 21956 KVTDTSKTTVSLEW 21969
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 18697 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18753
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 18754 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18805
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 23443 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23502
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1154
Y KN G + +V + D P P+ E DAT +
Sbjct: 23503 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23547
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 23548 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23597
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 23598 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23638
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1327
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 23639 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23693
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1363
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 23694 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23735
Score = 60.5 bits (145), Expect = 1e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 13284 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13342
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 13343 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13371
Score = 60.5 bits (145), Expect = 1e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1256 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 22235 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22293
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22340
Score = 60.5 bits (145), Expect = 1e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 26542 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26600
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 26601 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26637
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1315
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 15448 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15506
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 15507 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15538
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W K K + MKV + G Y + EN G + + V
Sbjct: 19328 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19376
Query: 1262 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1317
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19436
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 19437 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19492
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/318 (23%), Positives = 124/318 (38%), Gaps = 51/318 (16%)
Query: 430 TVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 489
T K EG V F L+D V E L+C V + W N ++
Sbjct: 2211 TAKLIVEGAVV-----EFVKELQDIEVPESYSGELECIVSPENIEG-KWYHNDVELKSNG 2264
Query: 490 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 546
T G L ++D ED G Y+ + + KK++ K +
Sbjct: 2265 KYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---------------KKTTCKLKM---- 2305
Query: 547 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG 606
KP LQGLSD KV +G V + V+VS E +W+ +G E+Q S+ H
Sbjct: 2306 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV-EGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 607 TQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
H L I+++ ED G Y+ +++G V +V I+ + V
Sbjct: 2362 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV------------ITPLKDVN 2409
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
G ++ C ++ +V W + + + K + + LV+ + G
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGP 2468
Query: 723 YEILLKNRVGECSCQVSL 740
Y++++ RV E +C +S+
Sbjct: 2469 YKLIV-GRV-ETNCNLSV 2484
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3643 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3702
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3703 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3751
Score = 58.9 bits (141), Expect = 4e-08
Identities = 35/114 (30%), Positives = 59/114 (51%), Gaps = 3/114 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME-EGEGEGEEEEE 1794
D L I++ +D+ YT A N++G+ + TA L +E + + G++ E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGKDVRE 3403
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1062 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 7825 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7868
Query: 1121 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1180
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 7869 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7919
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
R G W+K K + +V + G+++ + G
Sbjct: 7920 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7960
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 7961 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 8014
Query: 1298 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 8015 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8074
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1387
+ +P ++E D E E V +R V + T
Sbjct: 8075 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8112
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 17332 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17391
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
A N AG V V D P P V G S+ K
Sbjct: 17392 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17434
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1219
+PP I + +++ E+ L V ++ +T
Sbjct: 17435 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17470
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1274
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 17471 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17525
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1332
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 17526 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17585
Query: 1333 FRVRAINVYGTSEPS 1347
FRV A N G EPS
Sbjct: 17586 FRVSAENAAGVGEPS 17600
Score = 58.5 bits (140), Expect = 6e-08
Identities = 63/295 (21%), Positives = 120/295 (40%), Gaps = 37/295 (12%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEA 494
L V+E P F+ L+D +E + +LQC + P + W +G+ I+ +++ +
Sbjct: 5706 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADG 5764
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
L ++ AL D G YTC G S + + +++
Sbjct: 5765 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDREIK----------------- 5803
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
++ L ++VM+ ++S + W G + ++ D ++ G HSL +
Sbjct: 5804 -LVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIKEEGKIHSLVLH 5861
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ TG +A N V++ A L V+ G + + VT + G++ C
Sbjct: 5862 NCRLDQTGGVDFQAAN----VKSSAHLRVKPRVIG----LLRPLKDVTVTAGETATFDCE 5913
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
++ + P V W GK L + + V TL L+ V+ AG+ ++ K+
Sbjct: 5914 LSYEDIP-VEWYLKGKKL-EPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5966
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1021 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1078
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 18394 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18453
Query: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138
++ ++ + D G Y N G V V D P P
Sbjct: 18454 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18500
Query: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1198
V G ++ P A + II+ E ++
Sbjct: 18501 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18542
Query: 1199 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 18543 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18588
Query: 1259 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1312
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 18589 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18648
Query: 1313 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
T V L H Y+FRV A N G EPS+ S
Sbjct: 18649 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18686
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 24226 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24284
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 24285 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24335
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 24336 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24373
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 24374 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24433
Query: 269 SDV 271
S V
Sbjct: 24434 SAV 24436
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1317
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 24518 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24576
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 24577 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24627
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1087
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1145
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25609
Query: 1146 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1181
GTES +A V KPA T K +I + E++K+R
Sbjct: 25610 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25664
Score = 57.8 bits (138), Expect = 9e-08
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1747
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 9e-08
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 17882 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17941
Query: 1297 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 17942 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17991
Score = 57.8 bits (138), Expect = 9e-08
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1670 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25468 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25527
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25528 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25587
Query: 1787 GEGEEEEE 1794
E + +EE
Sbjct: 25588 QEFKSKEE 25595
Score = 57.4 bits (137), Expect = 1e-07
Identities = 65/290 (22%), Positives = 112/290 (38%), Gaps = 42/290 (14%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAEL 499
A LK+ V E QD V + V + W+ NG ++ YA S + + L
Sbjct: 2660 AVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV-KGTIYSL 2718
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ D Y LG++ SA + V K +K +
Sbjct: 2719 RIKNCAIVDESVYGF----RLGRLGASARLHVETVKIIKKPK------------------ 2756
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
D+ ++ + V V VS + P V W H EI+ S+ H L +Q + P
Sbjct: 2757 --DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPS 2813
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679
D G YT G++ +A L V+ H I P + TAS C ++
Sbjct: 2814 DAGEYTA----VVGQLECKAKLFVETLHITKTMKNIEVPETKTAS------FECEVSHFN 2863
Query: 680 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
P++ WL++G + + + F+++ + L++ + +Y + N
Sbjct: 2864 VPSM-WLKNGVEI-EMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2911
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1747
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 17612 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17670
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1373
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17724
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1233 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1289
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 18958 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 19017
Query: 1290 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 19018 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)
Query: 852 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 909
E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V +
Sbjct: 4334 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392
Query: 910 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 964
S+ ++K + + S + E K E+ L + GP+ P+ + E
Sbjct: 4393 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4450
Query: 965 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1014
+ NAK DE K + V + VN + H G
Sbjct: 4451 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4509
Query: 1015 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1069
T + K + + AP K+K++ + VA G C++ S P W G+ +
Sbjct: 4510 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4569
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1129
+ + + S+ I + D G Y C A N+ G C+ +TV P E
Sbjct: 4570 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4628
Query: 1130 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+ R+P+ VL + ++K+P PK PK + PE + E V
Sbjct: 4629 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4684
Query: 1187 EL 1188
E+
Sbjct: 4685 EV 4686
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 10231 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10288
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
+AKN+AG+ + + V V D P T P + S
Sbjct: 10289 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10328
Query: 1160 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
++ F PED G PIT ++ +++ V
Sbjct: 10329 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10362
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1272
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 10363 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10421
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1330
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 10422 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10481
Query: 1331 YKFRVRAINVYGTSEPS 1347
Y++RV A+N+ G +PS
Sbjct: 10482 YEYRVSAVNIVGQGKPS 10498
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A+N G+ + V D P PP + D
Sbjct: 14835 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14865
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
+ + F D G V Q + TW++ + + +
Sbjct: 14866 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14914
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 14915 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14968
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 14969 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 15028
Query: 1336 RAINVYGTSEPSQESE 1351
A N+ G S+PS+ SE
Sbjct: 15029 IAENMAGKSKPSKPSE 15044
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 988 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1046
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 22301 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22360
Query: 1047 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1106
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 22361 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22420
Query: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
AG S V V P P + V +++ V PK
Sbjct: 22421 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22467
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+ I++ E T W ++ ++ K+
Sbjct: 22468 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22497
Query: 1227 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1282
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 22498 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22555
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 22556 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22615
Query: 1341 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
G S+ S+ S + + P + EV+D
Sbjct: 22616 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22644
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1318
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 14367 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14426
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 14427 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14477
Query: 1379 DYRTVTINTEQKVSDFYDIEER 1400
RT+ + + F I+ R
Sbjct: 14478 -RRTLVVRAGLSIRIFVPIKGR 14498
Score = 56.2 bits (134), Expect = 3e-07
Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELH 500
P F +L + EGQ + V G P P + W +GQP+ + G+ LH
Sbjct: 25490 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25549
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY 542
I+D LPED G Y A N G SC A + V E+ +K E+
Sbjct: 25550 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-ERLRYKKQEF 25590
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1657 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1714
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1715 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 1775 AELIVETMEE 1784
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 14629 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14687
Query: 1291 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 14688 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14746
Query: 1351 ELTTVGEKPEEPK 1363
V E+ P+
Sbjct: 14747 RPVIVKEQTMLPE 14759
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1266 A 1266
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1743
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24619 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24678
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
LII+ V DD Y +A N G + TA L VE
Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26887
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26888 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26923
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1319
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 10117 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10174
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 10175 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10227
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1317
KP P P D + L W DGGS + Y +E W + R
Sbjct: 11497 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11556
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 11557 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1199
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 12077 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12134
Query: 1200 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
W+ K MKV+N +H + + EN++G + + V
Sbjct: 12135 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12183
Query: 1260 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1309
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 12184 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12243
Query: 1310 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 12244 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303
Query: 1367 EVS 1369
+ S
Sbjct: 12304 DAS 12306
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1330
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 23340 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23399
Query: 1331 YKFRVRAINVYGTSEPSQESELTTV 1355
Y FR+RA N G SEP + TV
Sbjct: 23400 YLFRIRAQNEKGVSEPRETVTAVTV 23424
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 498
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 24622 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24681
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 24682 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24727
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 24728 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24783
Query: 619 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 665
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 24784 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24843
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA 691
G S + + + WLR G+A
Sbjct: 24844 GGSKITNYIVEKCATTAERWLRVGQA 24869
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1314
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 9707 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9765
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1362
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 9766 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9812
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1239 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 21524 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21583
Query: 1297 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1350
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 21584 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639
Query: 1351 ELTTVGEKPEEP 1362
+ ++ P
Sbjct: 21640 GIIMTRDENVPP 21651
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1677 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 1737 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1089
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 10519 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10574
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
KA D G Y V +N G + CQV V D P PPV
Sbjct: 10575 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10616
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
D K P I +K G+ V + + + TC K K +
Sbjct: 10617 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10672
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 10673 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10717
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1326
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 10718 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10772
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1379
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 10773 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10825
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 15828 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15870
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 15871 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16995
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 16996 GITVANVVGQKTASIEI 17012
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1745
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25443
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25444 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 1667 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4511 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4566
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4567 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4624
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26536 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26595
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1788
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26596 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26645
Score = 53.5 bits (127), Expect = 2e-06
Identities = 66/288 (22%), Positives = 114/288 (39%), Gaps = 41/288 (14%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDA 504
+ +K+ V E + +C V VP + WL NG I+ + + + +L I +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNT 2897
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG-LSDL 563
ED YT + N QVS + VT PI + L D+
Sbjct: 2898 STEDSAEYTFVCGN--DQVSATLTVT-----------------------PIMITSMLKDI 2932
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
+ +T V V+ WL NG EI+ ++ + HSL I+ V D
Sbjct: 2933 NAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAAD 2991
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
YT AG+ + A L V+ H F + + + + C ++ +P TV
Sbjct: 2992 YTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLEKKRAMFECEVS-EPDITV 3042
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 731
W++D + L + T ++ + + V L++ + AG+Y ++ V
Sbjct: 3043 QWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3089
Score = 53.1 bits (126), Expect = 2e-06
Identities = 95/436 (21%), Positives = 157/436 (36%), Gaps = 67/436 (15%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16706
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
T + N SG + SA ++++ LD+ + N V + + +S + L+
Sbjct: 16707 TLTLENSSG--TKSAFVTVRVLDT-------PSPPVNLKVTEITKDSVSITWEPPLLDGG 16757
Query: 292 AKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
+K KN +R + +AA K++ ++ + V + I L A
Sbjct: 16758 SKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEG--CSYYFRVTAENEYGIGLPAQ 16815
Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
P A V P G+ + +P D SK + M+ +
Sbjct: 16816 TADPIKVAE---VPQPPGKITVDDVTRNSVSLSWTKP---EHDGGSKIIQYIVEMQAKHS 16869
Query: 411 SAFPKFESKPQSQEVKENQT----VKFRC-----------EGLAVMEVA------PSFSS 449
+ + Q V N T FR LAV VA P
Sbjct: 16870 EKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKP 16929
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALP 506
+V GQD ++ + G P P ITW +G P++ T + L I++
Sbjct: 16930 AFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHK 16989
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+D G Y N +GQ + S + +K P P P+ +S
Sbjct: 16990 DDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFDDVS----- 17031
Query: 567 DGSQVTMTVQVSGNPP 582
++ +S NPP
Sbjct: 17032 -----AESITLSWNPP 17042
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21722
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 21723 VYTVEAKNASGSAKAEIKVKVQ 21744
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24228 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24287
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24288 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 665
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23550
Query: 666 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 721
G + L + WL +++ + T F L + + + + G
Sbjct: 23551 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23610
Query: 722 QYEILLKNRVGECSCQVSL 740
Y L++ V EC + +
Sbjct: 23611 SY---LQSEVIECRSSIRI 23626
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1661 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1720
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15816 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15874
Query: 1721 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15875 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15932
Score = 52.4 bits (124), Expect = 4e-06
Identities = 94/441 (21%), Positives = 159/441 (36%), Gaps = 63/441 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V ++ G R ++GRP P +TW K + L A + +E + +++ VN+ D G
Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAG 23208
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVRKE---------VTNVI 279
YT N SGK S + + + S V+E + + E V N I
Sbjct: 23209 KYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYI 23268
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSP------------PWAANSQPQPPRESKLESCKD 327
++ + + CS S P +P S +
Sbjct: 23269 VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 23328
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
P + V+ T S++TL +P G L+ E + R T +P
Sbjct: 23329 VPLVPAKLEVVDVTKSTVTL----AWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23384
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSF 447
+ V S EG++ + +++ E +E T + L V+
Sbjct: 23385 TVLEHTVTSL-------NEGEQYLFRIRAQNEKGVSEPRETVTA-VTVQDLRVLPTIDLS 23436
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCE--AGVAELHIQDA 504
+ K V G+ L + G P P +W G ++ + R T E VA+L I++
Sbjct: 23437 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 23496
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
D G YT +N G S + V + +K P PT PI +
Sbjct: 23497 TIRDTGEYTLELKNVTGTTSETIKVIILDK-------------PGPPTGPI------KID 23537
Query: 565 VMDGSQVTMTVQVSGNPPPEV 585
+D + +T++ + PPE+
Sbjct: 23538 EIDATSITISWE-----PPEL 23553
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1211
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 24010 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24069
Query: 1212 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1263
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 24070 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24127
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1321
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 24128 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24186
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1369
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 24187 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24238
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 25273 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25332
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 25333 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25367
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10978
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 10979 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 11026
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P G SV V + W ++ H
Sbjct: 11027 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 11064
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1272
+E L +AA EN+ G + DP P G P
Sbjct: 11065 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11112
Query: 1273 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 11113 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11172
Query: 1331 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
Y+FRV+A N+ G P + EK P E++V
Sbjct: 11173 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11209
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 21663 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21721
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765
Score = 51.6 bits (122), Expect = 7e-06
Identities = 90/418 (21%), Positives = 158/418 (37%), Gaps = 69/418 (16%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14538
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 14539 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14596
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 14597 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14656
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T
Sbjct: 14657 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV 14712
Query: 386 QPGLGSQDVVSKAANR-----RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAV 440
+ G + VV ++ + P+ ES+P + + QT+ L
Sbjct: 14713 K---GLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRP---VIVKEQTM------LPE 14759
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVA 497
+++ + ++ A G + ++ V G P P +TW Q + Q A
Sbjct: 14760 LDLRGIYQKLVIAKA---GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 14816
Query: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
L+I + + D G Y A N +G+V + VH+ P PT PI
Sbjct: 14817 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14861
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1258
W K K + + H KV G + + EN G +
Sbjct: 20411 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20459
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 20460 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20518
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1348
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 20519 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20551
Score = 51.2 bits (121), Expect = 9e-06
Identities = 55/198 (27%), Positives = 76/198 (38%), Gaps = 39/198 (19%)
Query: 452 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPED 508
KD +E + SV VP + W +P R E V +L +Q+ P D
Sbjct: 2756 KDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSD 2814
Query: 509 HGTYTCLAENALGQVSCSAWV---TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 565
G YT + +GQ+ C A + T+H K+ + E P TA
Sbjct: 2815 AGEYTAV----VGQLECKAKLFVETLHITKTMKNIE-----VPETKTA------------ 2853
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 625
+ +VS P + WL NG EI+ SE F +G H L I ED+ YT
Sbjct: 2854 ------SFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYT 2906
Query: 626 CEAWNSAGEVRTQAVLTV 643
N + A LTV
Sbjct: 2907 FVCGND----QVSATLTV 2920
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1316
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 8695 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8752
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 8753 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8804
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1056 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1114
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 20994 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 21053
Query: 1115 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1169
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 21054 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21105
Query: 1170 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1229
TW + + ++ SE
Sbjct: 21106 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21131
Query: 1230 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1287
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 21132 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21182
Query: 1288 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 21183 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21242
Query: 1348 QESELTTVGEKPEEPKDEVEVSD 1370
+ TV E P EV++SD
Sbjct: 21243 TIGPI-TVKELIITP--EVDLSD 21262
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1274
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 21903 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21960
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1332
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 21961 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 22020
Query: 1333 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
FRV AIN G + + + ++ P+ +++ +
Sbjct: 22021 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 22057
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 24225 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24283
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
TL + + G Y + N VGE L+LQ
Sbjct: 24284 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24318
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7427
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 7428 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7487
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 7488 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7522
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 9294 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9352
Query: 1316 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1370
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 9353 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9410
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 13403 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13462
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G+ E + V V D P PPV T + + P
Sbjct: 13463 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13504
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P II + ++ + K T C+ FR V N E
Sbjct: 13505 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13547
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1279
G + + EN+ G V P G +RS SS
Sbjct: 13548 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13595
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1339
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 13596 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13654
Query: 1340 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
G P SE+T V +D+V D D K
Sbjct: 13655 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13680
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16991
Query: 720 AGQYEILLKNRVGECSCQVSLM 741
GQY I + N VG+ + + ++
Sbjct: 16992 GGQYGITVANVVGQKTASIEIV 17013
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 13059
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 13060 DYTITAENSSGSKSATIKLKV 13080
Score = 48.9 bits (115), Expect = 4e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1062 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167
Query: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
P PP S+ + +K TPP I + +++
Sbjct: 14168 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14207
Query: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1241
E+ L W + IQ H+ + + G++ + H G
Sbjct: 14208 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14248
Query: 1242 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 14249 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14303
Query: 1300 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1357
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 14304 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14363
Query: 1358 K--PEEPKDEVEVSDDDEK 1374
P P V+D +K
Sbjct: 14364 AAYPPGPPSNPHVTDTTKK 14382
Score = 48.5 bits (114), Expect = 6e-05
Identities = 92/445 (20%), Positives = 156/445 (35%), Gaps = 76/445 (17%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10982
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANR----SFVRET------KATNSDVRKEVTNVISK 281
+ V N +G ++S ++ + R S +R+ K D +TN + +
Sbjct: 10983 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 11042
Query: 282 ESKLDS-----LEAAAKSKN--CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQ 334
+ S L A +K K+ G + ++ Q R +E+ K P
Sbjct: 11043 RRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPL 11102
Query: 335 TPV--------LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
P + + ++L + + +P G L EE
Sbjct: 11103 HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEE---------------- 11146
Query: 387 PGLGSQDVV--SKAANRRIPMEGQRDSAFPKFESKPQS--QEVKENQTVKFRCEGLAVME 442
G+QD + N + G + +F K ++ + T+ C+ V
Sbjct: 11147 ---GTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPP 11203
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAEL 499
+++ V G +RG PVP W +G I ++ + + L
Sbjct: 11204 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVL 11263
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ L D G Y NA G + + +TV + P PT PI
Sbjct: 11264 TIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD-------------VPGPPTGPI---- 11306
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPE 584
++D + MT +S PP +
Sbjct: 11307 ----NILDVTPEHMT--ISWQPPKD 11325
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 12962 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 13020
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 13021 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13077
Query: 121 LTV 123
L V
Sbjct: 13078 LKV 13080
Score = 48.5 bits (114), Expect = 6e-05
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+ K G+ + GRP P VTW K L AR S+ + +L I V ++D G
Sbjct: 20976 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 21035
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDS 255
Y + NG G+ S+ +S++ LD+
Sbjct: 21036 KYILTIENGVGEPK-SSTVSVKVLDT 21060
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1256 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 23719 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23776
Query: 1314 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 23777 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23834
Score = 48.1 bits (113), Expect = 7e-05
Identities = 88/408 (21%), Positives = 158/408 (38%), Gaps = 69/408 (16%)
Query: 179 RFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
R I GRP P+V W + + + + S+ + +L + VN+ D G Y V N
Sbjct: 15574 RLFVPIKGRPAPEVKWARDHG--ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS 15631
Query: 239 SGKASMSAELSIQGLDSANRSF---VRETKATNS---------DVRKEVTNVISKESKLD 286
SG S SA ++++ LD+ V+E T+ D ++ N I ++ +
Sbjct: 15632 SG--SKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 15689
Query: 287 SLEAAAKSKNCSSP-------QRGGSPPWAANSQPQP----PRESKLESCKDSPRTAP-- 333
+ + NC Q G S + ++ + P E+ ES K S R P
Sbjct: 15690 RKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETA-ESVKASERPLPPG 15748
Query: 334 QTPVLQKTSSSITLQAARVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLG 390
+ ++ T +S++L + + + + LG + G ++ T T GL
Sbjct: 15749 KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATIT-GL- 15806
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSV 450
+ + + R+ + ++ + P+ S P + + + P+F +
Sbjct: 15807 ---IQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---------------LVIPPAFKLL 15848
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPE 507
V+ G+D + G P P +TW + P+ Q R E+ + L I+DA E
Sbjct: 15849 FNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 15908
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
D G Y N+ G+ + V V +K P PT P+
Sbjct: 15909 DVGHYVVKLTNSAGEAIETLNVIVLDK-------------PGPPTGPV 15943
Score = 48.1 bits (113), Expect = 7e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 19075 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19117
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 19118 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19175
Query: 249 SIQGLD 254
+I LD
Sbjct: 19176 TIIVLD 19181
Score = 48.1 bits (113), Expect = 7e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 19429 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19484
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 19485 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19544
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 19545 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1631 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1690
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 26190 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26249
Query: 1691 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 26250 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26308
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ IS V D+ Y+ NS G+ L ++
Sbjct: 26309 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346
Score = 47.8 bits (112), Expect = 1e-04
Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 14/132 (10%)
Query: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FE 603
++ S+ F + + ++++G VT ++SG P P++ W +G I+ E + F
Sbjct: 1237 ISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFL 1296
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS------- 656
Q G + SL I V PED G YT A N G L V+ P +I
Sbjct: 1297 QDG-RASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSR 1355
Query: 657 ----KPRSVTAS 664
PRSV+ S
Sbjct: 1356 IRSLSPRSVSRS 1367
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1739
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 1740 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1194 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1253
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 7210 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Query: 1254 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1307
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7327
Query: 1308 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 7328 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7387
Query: 1367 EV 1368
+V
Sbjct: 7388 DV 7389
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
VT +G +V + G P P++ WL+DG L K++ + E+ TL +K + H
Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPL-KESEFVRFSKTENKITLSIKNAKKEHG 21326
Query: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRG 753
G+Y ++L N V C V + + + P+G
Sbjct: 21327 GKYTVILDNAV--CRIAVPITVITLGPPSKPKG 21357
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 506 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 561
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 21615 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21664
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 21665 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21721
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE 645
G YT EA N++G + + + VQ+
Sbjct: 21722 GVYTVEAKNASGSAKAEIKVKVQD 21745
Score = 47.4 bits (111), Expect = 1e-04
Identities = 117/571 (20%), Positives = 206/571 (36%), Gaps = 81/571 (14%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
E P F KL E C+++ V W K + PS + S+ ++
Sbjct: 5355 EADPYFTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI 5412
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS---ANRSFVRET-----KATNS 269
L+I + D G Y C KA+++ E + ++ FV ET + +
Sbjct: 5413 LKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEP 5472
Query: 270 DVR---KEVTNVISKESKLDSLEAAAKS----KNCSSPQRGGSPPWAANSQPQPPRESK- 321
DV K ++ + +E K NC G AAN++ + K
Sbjct: 5473 DVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKE 5532
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
L +P + V +K + + +R +P+ G +G++R
Sbjct: 5533 LPLIFITPLS--DVKVFEKDEAKFECEVSR-EPKTFRWLKGTQEITGDDR---------- 5579
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
F + G V+ AA D A FE++ ++ + K EG+ +
Sbjct: 5580 FELIKDGTKHSMVIKSAA--------FEDEAKYMFEAE------DKHTSGKLIIEGIRLK 5625
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 501
+ P LKD E + V + + R+ W N Q + RS + +
Sbjct: 5626 FLTP-----LKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSM 5671
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
QD T+ L+ + Q+ A SE L V P F L
Sbjct: 5672 QDEGKTHSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQ 5720
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D ++ +V + ++S P V W +G EI+ S++ + G + L +++ D
Sbjct: 5721 DYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDI 5779
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 681
G YTC+ G +T L +++ + + SV ++ I+ D
Sbjct: 5780 GQYTCD----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI- 5830
Query: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 712
+W G+AL + T E+ + + +LVL
Sbjct: 5831 HANWKLKGEALLQ-TPDCEIKEEGKIHSLVL 5860
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 6984 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 7042
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 7043 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7097
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 563
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 12941 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 13000
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 620
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 13001 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 13057
Query: 621 TGTYTCEAWNSAG 633
+G YT A NS+G
Sbjct: 13058 SGDYTITAENSSG 13070
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 13688 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13747
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 13748 YTITLKNVAGTKEGTISIKVVG 13769
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 18062
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 18063 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21686
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21687 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1318
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 22935 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22993
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 22994 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 23037
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 23115 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23172
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 23173 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23229
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)
Query: 919 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 976
++++ + +GS E + VES +S + S V K + +A ++
Sbjct: 4333 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4392
Query: 977 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
K + KP E + +S E ++V V + G + P L
Sbjct: 4393 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4442
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1095
D EG + L +++ + W K + + + Q+ + ++ I+K ED
Sbjct: 4443 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4500
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
+G Y C A ND+G+ S ++TV K
Sbjct: 4501 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4525
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+ AP K E +V G + ++ + W K ++I ES+
Sbjct: 4526 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4575
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ +S+ S L IL + CG YT N+ GS LTV
Sbjct: 4576 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4618
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)
Query: 683 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 741
V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L
Sbjct: 4464 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4522
Query: 742 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 801
+ +A + R EP ++ G + ++R W G+ + E D +R
Sbjct: 4523 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4578
Query: 802 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 848
+L+ +V + ++T +A + L G+K K L E K
Sbjct: 4579 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4636
Query: 849 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 894
P E++ ++ L++ + +PK ++ KV P ++V+ +V ++
Sbjct: 4637 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4694
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 954
K P P KVP KPA P LPA E A+ P +P+
Sbjct: 4695 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4740
Query: 955 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1014
PV P K A E KP G P + + + ++ + + G
Sbjct: 4741 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4795
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1068
+ + + F ++++D+ + E G + +C VS P+T I W +G
Sbjct: 4796 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4852
Query: 1069 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 4853 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4906
Score = 47.0 bits (110), Expect = 2e-04
Identities = 104/465 (22%), Positives = 165/465 (35%), Gaps = 67/465 (14%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 8754 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8808
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8867
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 8868 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8927
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 8928 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8987
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 8988 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 9043
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
PT + + D + R+ + + P Q+ + T+K R
Sbjct: 9044 CPTTSFLVENLDE-HQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL------ 9096
Query: 442 EVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA------ 494
SV D ++ G+ + V G P+P+I W N I+ +
Sbjct: 9097 -------SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9149
Query: 495 ---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
EL I A+ ED GTYT A N LG V + V V+++ S
Sbjct: 9150 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9194
Score = 47.0 bits (110), Expect = 2e-04
Identities = 109/532 (20%), Positives = 188/532 (35%), Gaps = 89/532 (16%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 10523 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10581
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V +G + D + +P +
Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM---VISWKPPL-----D 10633
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEI 220
+K+ ++++ ++G+ W+ + + + +VS + + I
Sbjct: 10634 DGGSKITNYIIEKKEVGKD------------VWMPVTSASAKTTCKVSKLLEGKDYIFRI 10681
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVR 272
H N G+ LV + SM A+ + D+ ++ V E ++ D
Sbjct: 10682 HAENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 10734
Query: 273 KEVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQP 316
K +TN I ++ + S A +K+ C R + P P
Sbjct: 10735 KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSP 10794
Query: 317 PRE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERK 372
P + +K K SP P+ S +T Q R + G V G+E
Sbjct: 10795 PSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW 10854
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKF---------ESKPQSQ 423
R A P + P + + G RD KF ES P
Sbjct: 10855 RRANHTPESCP----------------ETKYKVTGLRDGQTYKFRVLAVNAAGESDPA-- 10896
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
V E VK R E ++ A ++ ++ + G L ++G P P++TW +
Sbjct: 10897 HVPEPVLVKDRLEPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDR 10952
Query: 484 PIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
AR ++L I++A ED G Y+ EN G + S V V +K
Sbjct: 10953 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 11004
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1042 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1100
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 25276 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25335
Query: 1101 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1159
C ND G+ ++ V + + RR T+KK K
Sbjct: 25336 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25375
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1216
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 25376 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25435
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1265
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 25436 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25495
Query: 1266 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
G +IR S + TL W DG +IEI +
Sbjct: 25496 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25546
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 25547 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25603
Query: 1376 PEVDYRTVTI 1385
+ R I
Sbjct: 25604 IDKTLRMAEI 25613
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ + + +G A FE V G P P VTW + + + + + + G+ + +
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
++ ED G Y C+A N G EL V P +K+ +
Sbjct: 3827 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3886
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PAVE S + AT + ++K + + +++ + L +PL
Sbjct: 3887 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3941
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
S+ E++ + + + C +NGS S L +Q + S ++F
Sbjct: 3942 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3990
Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ ET+A SD K + +S E +++SL + P+ G P
Sbjct: 3991 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 4044
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
S +PP S L S + +P+ + T+ +TLQ Q
Sbjct: 4045 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4087
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 13682 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13740
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 13741 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13769
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1648 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1702
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26376 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26435
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26436 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26486
Query: 1763 K 1763
+
Sbjct: 26487 E 26487
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVD 1119
D G YK + G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6067 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6122
Query: 1745 CSLIISDVCGDDDAKYTCK 1763
L+I+ DD+A+Y+C+
Sbjct: 6123 RILVINKCLLDDEAEYSCE 6141
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 496
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 21652 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21708
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
L ++DA + G YT A+NA G V V +
Sbjct: 21709 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21745
Score = 45.8 bits (107), Expect = 4e-04
Identities = 88/439 (20%), Positives = 162/439 (36%), Gaps = 71/439 (16%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 25924 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25983
Query: 311 --NSQPQPPRESKLESCKDSP---RTAPQTP--VLQKTSSSITLQAARVQPEPRAPGLGV 363
S+PQP E + ++ + SP RT P++P V + S S ++AR R +
Sbjct: 25984 LIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKA 26043
Query: 364 L---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
+ E + +P T + + + + R+P GQ +SKP
Sbjct: 26044 ALKTQKTSERKYEVLSQQPFTLDH------APRITLRMRSHRVPC-GQNTRFILNVQSKP 26096
Query: 421 QSQ--------EVKENQTVKF-RCEGLAVME--------------VAPSFSSVLKDCAVI 457
++ E++E+ + + G+ +E V ++ D A +
Sbjct: 26097 TAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 26156
Query: 458 E--GQDFVLQCSVR-GTPVPRITWLLNGQPIQYARST------CEAGVAELHIQDALPED 508
+ G D+ S R VPR + + YA S+ EA + ++ + E
Sbjct: 26157 DVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTET 26216
Query: 509 HGTYTCLAENALGQVSCSAWV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+ + +A ++ +A ++ EK ++RK + L A L + V
Sbjct: 26217 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVY 26268
Query: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 626
+G + G P P V WL G + S + + I V D G Y+
Sbjct: 26269 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 26328
Query: 627 EAWNSAGEVRTQAVLTVQE 645
NS G+ + LT+Q+
Sbjct: 26329 VVENSEGKQEAEFTLTIQK 26347
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 18018 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18077
Query: 625 TCEAWNSAG-EVRTQAVLTVQEP 646
T A NSAG +V+ +++P
Sbjct: 18078 TVTATNSAGTATENLSVIVLEKP 18100
Score = 45.1 bits (105), Expect = 6e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1159 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1215
P PP A P++ + +R E G I W+ K R I +
Sbjct: 22532 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22586
Query: 1216 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 22587 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22645
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1329
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 22646 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22705
Query: 1330 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 22706 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22744
Score = 44.7 bits (104), Expect = 8e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1317
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 12884 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12943
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 12944 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12995
Score = 44.7 bits (104), Expect = 8e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN-EDVFTLVLKKVQPWHAGQYE 724
G SV + I+G P PT+ W +D K L T ++N D+ ++++K ++G YE
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYE 20639
Query: 725 ILLKNRVGECSCQVSLML 742
+ L+N +G S + + +
Sbjct: 20640 LKLRNAMGSASATIRVQI 20657
Score = 44.3 bits (103), Expect = 0.001
Identities = 183/961 (19%), Positives = 338/961 (35%), Gaps = 154/961 (16%)
Query: 180 FSCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
F+C I + P + W KG +P +P+ + + L+I +D+ Y +
Sbjct: 5020 FACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 5078
Query: 238 GSGKASMS-AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
A ++ E ++ L + E ++ + D + I + KL E S
Sbjct: 5079 KRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD-IPGQWKLKG-ELLRPSPT 5136
Query: 297 CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP 356
C GG + L ++ TA T + ++ L+ V
Sbjct: 5137 CEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERR 5196
Query: 357 RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQR------D 410
+A VL+ P D++ + I +G++ D
Sbjct: 5197 QARFECVLTREANVIWSKGP----------------DIIKSSDKFDIIADGKKHILVIND 5240
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 470
S F + + EV+ +T L V + F S L+D V EG+ C +
Sbjct: 5241 SQFD--DEGVYTAEVEGKKT----SARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSH 5294
Query: 471 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
+ + W N + +R+ + + H + + E L +S
Sbjct: 5295 EKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQ 5341
Query: 531 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
V E S+ + + L P F L D ++ ++T+ +VS + P V W +
Sbjct: 5342 VKELSSTAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKD 5392
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN--SAGEVRTQA-VLTVQEPH 647
G EI S + + G + L I++ +D G Y C+ + V +A ++ V++P
Sbjct: 5393 GEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPL 5452
Query: 648 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNE 705
G + F+ + L + P VH W G+ L E++++
Sbjct: 5453 YGVEV-FVGETAHFEIELSE-------------PDVHGQWKLKGQPLTASPD-CEIIEDG 5497
Query: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR-------- 752
L+L Q G+ N + +V + S + +
Sbjct: 5498 KKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECE 5557
Query: 753 -GREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR 811
REP + L G + G DR+ ++ G + ++ ED + +
Sbjct: 5558 VSREPKTFRWLKGT---QEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED-- 5610
Query: 812 QHTE-----EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQR 862
+HT E IR + + L +D+ K+ V T LS D+++ + + N QR
Sbjct: 5611 KHTSGKLIIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQR 5662
Query: 863 QVKPKTVS-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKK 921
++VS ++E K HS + F+ L+ TS+ V + + K
Sbjct: 5663 LHTTRSVSMQDEGKTHS---ITFKD-LSIDDTSQIRVEAMG-------------MSSEAK 5705
Query: 922 LPAENGSS--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLK 979
L G + + + VE + + + S PV K + +KP NA
Sbjct: 5706 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------ 5759
Query: 980 PMGNAKPDENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
+K+ K+ LKK +K+D+ GT + + + + L
Sbjct: 5760 ----------IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLH 5809
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
V V E + + ++S D W L G+ L T + +EG + S+ + +
Sbjct: 5810 SVEVMETETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQT 5868
Query: 1097 G 1097
G
Sbjct: 5869 G 5869
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11271
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 11272 DTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 532 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 15820 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15879
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 649
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 15880 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15939
Query: 650 TQP 652
T P
Sbjct: 15940 TGP 15942
Score = 44.3 bits (103), Expect = 0.001
Identities = 81/396 (20%), Positives = 141/396 (35%), Gaps = 56/396 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 18812 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18869
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 18870 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18927
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 18928 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18987
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 18988 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 19047
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
GL G + V AA R P + E+K + + F +
Sbjct: 19048 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVI---ARDIEIKPSVELPFHTFNVKAR 19104
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAE 498
E + +G P + W +GQ ++ + V
Sbjct: 19105 E------------------QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS 19146
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
L I++A ED GTY N+ G ++ + V ++
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 19182
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 12594 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12652
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSG 12673
Score = 43.9 bits (102), Expect = 0.001
Identities = 112/518 (21%), Positives = 191/518 (36%), Gaps = 68/518 (13%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 22754 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22811
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22870
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 22871 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22930
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 22931 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22990
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 22991 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 23033
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 23034 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23091
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
R F +G + AA + ++G + S+ + E + V+ R E
Sbjct: 23092 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSE----------YSESIAEIEPVE-RIE 23137
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 496
+ +E+A + K + G L SV G P P ITW G +
Sbjct: 23138 -IPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES 23193
Query: 497 AELHIQDALPE-DHGTYTCLAENALGQVSCSAWVTVHE 533
L I D + D G YT AEN G+ S + V V++
Sbjct: 23194 YSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD 23231
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 9786 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9839
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 9840 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9895
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 9896 NLGTASKEMRLNVLG 9910
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1750
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9821 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9879
Query: 1751 DVCGDDDAKYTCKAVNSLGEAT 1772
D YT AVN+LG A+
Sbjct: 9880 QSRRSDTGLYTITAVNNLGTAS 9901
Score = 43.1 bits (100), Expect = 0.002
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11723
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12583 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12642
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12643 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1718
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16212 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16268
Query: 1719 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16269 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16327
Query: 1779 V 1779
V
Sbjct: 16328 V 16328
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1321
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 19678 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19736
Query: 1322 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1352
V+ L EY++RV A N G S PS+ S L
Sbjct: 19737 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19769
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1025 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1081
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
+++++ ED+G Y V
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401
Query: 1262 PDP 1264
P
Sbjct: 2402 ITP 2404
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1691 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1744
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4812 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4869
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+I DV D +YTC E T TA+L+VE +
Sbjct: 4870 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 17271 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17329
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 17330 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17387
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKV 17410
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 990 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1038
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021
Query: 1039 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1098
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080
Query: 1099 YKCVAKNDAGQAE 1111
Y VA + A+
Sbjct: 3081 YTVVAGGNVSTAK 3093
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 13398 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13457
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 13458 KYILTLENSCGK 13469
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14834
Query: 628 AWNSAGEVRTQAVLTVQ 644
A N GEV V+T+Q
Sbjct: 14835 ARNIVGEVGD--VITIQ 14849
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 507
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 16245 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16304
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 564
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 16305 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16351
Query: 565 -----VMDGSQVTMTVQVSGNPPPEVIW 587
+ DG + V ++W
Sbjct: 16352 AWKPPLQDGGSDIINYIVERRETSRLVW 16379
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16924 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16978
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+L I + DD +Y N +G+ T + E++
Sbjct: 16979 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 17013
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 19105 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19163
Query: 727 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
+ N G + +++++ + P + SC+ +
Sbjct: 19164 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19199
Score = 42.4 bits (98), Expect = 0.004
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 520 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK----VMDGSQVTMTV 575
+GQ V+ K S SE + + P + L+ DLK + G+ + + V
Sbjct: 23104 MGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMV 23163
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
VSG PPP + W G I + + + L + +V D G YT EA N +G+
Sbjct: 23164 SVSGRPPPVITWSKQG--IDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23221
Query: 636 RTQAVLTVQE 645
++ V +
Sbjct: 23222 SATVLVKVYD 23231
Score = 42.0 bits (97), Expect = 0.005
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1089
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 6039
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
PED Y C DA + SC + V
Sbjct: 6040 DCTPEDIKTYTC----DAKDFKTSCNLNV 6064
Score = 42.0 bits (97), Expect = 0.005
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 6154 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6212
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 6213 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6243
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 6244 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6293
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 6294 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6331
Score = 42.0 bits (97), Expect = 0.005
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 11203 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11262
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
L I+ DTG Y N+AG LTV
Sbjct: 11263 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 13058
Query: 721 GQYEILLKNRVGECSCQVSL 740
G Y I +N G S + L
Sbjct: 13059 GDYTITAENSSGSKSATIKL 13078
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 22063 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22120
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 22121 YTLTVENNSGSKSITFTVKV 22140
Score = 42.0 bits (97), Expect = 0.005
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 570
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 22709 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22759
Query: 571 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 630
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 22760 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22819
Query: 631 SAGEVRTQAVLTVQEPHDGTQP 652
++G T+AV + + D P
Sbjct: 22820 ASG---TKAVSVMVKVLDSPGP 22838
Score = 42.0 bits (97), Expect = 0.005
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 22731 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22780
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22835
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6217
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1793
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6218 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6265
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 17295 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17352
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 17353 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17408
Query: 122 TV 123
V
Sbjct: 17409 KV 17410
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19948
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 19949 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19987
Score = 41.6 bits (96), Expect = 0.007
Identities = 34/133 (25%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
TCE Q +E V K L PV T+G + T + P
Sbjct: 21212 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV---TIGPITVKELIITPEVDLSDIPG--- 21265
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
+V V+ G G+P+P ++WLK +PL+ S V S+ L I
Sbjct: 21266 ---AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAK 21322
Query: 225 QDDVGVYTCLVVN 237
++ G YT ++ N
Sbjct: 21323 KEHGGKYTVILDN 21335
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1744
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 27022 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27080
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+LII DV D YT N G + T + + ++
Sbjct: 27081 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27118
Score = 41.2 bits (95), Expect = 0.009
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 8079 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8138
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 8139 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174
Score = 41.2 bits (95), Expect = 0.009
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 501
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 8082 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8141
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++ D G YT EN LG + S V V
Sbjct: 8142 PKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 41.2 bits (95), Expect = 0.009
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11268
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D +Y N+ G T L V
Sbjct: 11269 LRRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18471
Query: 721 GQYEILLKNRVGECSCQVSL 740
GQY + L N G S +++
Sbjct: 18472 GQYILKLSNVGGTKSIPITV 18491
Score = 41.2 bits (95), Expect = 0.009
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 22752 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22811
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y KN +G S V V D+P
Sbjct: 22812 KYTLTVKNASGTKAVSVMVKVLDSP 22836
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 535 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7425
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 7426 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7473
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7390 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7448
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y +AVN G AT E+ V
Sbjct: 7449 KRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1320
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 7779 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7837
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSE 1345
V L Y FRV A N G S+
Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSD 7862
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 12594 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12652
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 12653 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 16248 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16307
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 16308 NYILKAKNVAGERSVTVNVKV 16328
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 16936 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16994
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 16995 YGITVANVVGQKTASIEI 17012
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 18063
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + DD KYT A NS G AT +IV
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 19106 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19165
Query: 630 NSAGEVRTQAVLTV 643
NSAG + + V
Sbjct: 19166 NSAGSITVPITIIV 19179
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 642 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 688
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 19462 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19521
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 19522 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19571
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5982 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 6039
Query: 1751 DVCGDDDAKYTCKA 1764
D +D YTC A
Sbjct: 6040 DCTPEDIKTYTCDA 6053
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11671
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 11672 GKYIISAKNSSGHAQ 11686
Score = 40.4 bits (93), Expect = 0.016
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCL 515
GQ + V+G P P ITW G+ + + + EL I++A+ DHG Y
Sbjct: 11618 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11677
Query: 516 AENALGQVSCSAWVTVHEK 534
A+N+ G SA V V ++
Sbjct: 11678 AKNSSGHAQGSAIVNVLDR 11696
Score = 40.0 bits (92), Expect = 0.020
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 10894 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10953
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 10954 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 529 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 587
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 16899 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16958
Query: 588 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 646
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 16959 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 17018
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 506
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y N G S V V ++ P P P+ + G++
Sbjct: 18469 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18510
Score = 40.0 bits (92), Expect = 0.020
Identities = 20/73 (27%), Positives = 29/73 (39%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G V + + G PPP V W + + + E + L I +V DTG Y
Sbjct: 20981 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 21040
Query: 628 AWNSAGEVRTQAV 640
N GE ++ V
Sbjct: 21041 IENGVGEPKSSTV 21053
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
G AKF ++ P + W + G+ I + C IR + SL I D G+
Sbjct: 4543 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4598
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
YTC+A+N G+ T LTV G+ V K L +R P E
Sbjct: 4599 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4641
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1668 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5686 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5744
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5745 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5784
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 7367 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7426
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 7427 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 39.7 bits (91), Expect = 0.027
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 11215 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11274
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 11275 EYQITVSNAAGSKTVAVHLTV 11295
Score = 39.7 bits (91), Expect = 0.027
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 19/124 (15%)
Query: 446 SFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAG----VAELH 500
S +D V+ G+ F L+ V G P+P I WL + I+ + + CE A L
Sbjct: 17321 SMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES-ARCEIKNTDFKALLI 17379
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
++DA+ D G Y A N G S V V ++ P P P+ + G+
Sbjct: 17380 VKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-------------PGPPEGPVQVTGV 17426
Query: 561 SDLK 564
+ K
Sbjct: 17427 TSEK 17430
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 17688 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17747
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 17748 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17804
Query: 121 LTV 123
+ V
Sbjct: 17805 VKV 17807
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23208
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y A+N +G+ + V V D P
Sbjct: 23209 KYTIEAENQSGKKSATVLVKVYDTP 23233
Score = 39.3 bits (90), Expect = 0.035
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 710
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 711 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 770
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 771 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 824
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 825 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 884
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 885 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 936
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPA 963
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8071 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8130
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
D + L + D YT N LG AT + + V
Sbjct: 8131 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8171
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 506
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 8804 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8863
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 8864 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8918
Query: 567 DGSQVT 572
GS++T
Sbjct: 8919 GGSEIT 8924
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 716
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9577
Query: 717 PWHAGQYEILLKNRVGE--CSCQVSLM 741
H G+Y I KN+ G+ +C+V +M
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVM 9604
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 599 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 16190 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16246
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 16247 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16302
Query: 717 PWHAGQYEILLKNRVGECSCQVSL 740
+G Y + KN GE S V++
Sbjct: 16303 RVDSGNYILKAKNVAGERSVTVNV 16326
Score = 38.9 bits (89), Expect = 0.045
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 3/105 (2%)
Query: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740
A+E P ++D+ V G A+F C ++ +V W + I ES ++
Sbjct: 3481 AKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESE--RLKQS 3538
Query: 1741 EDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
++GN L I +V D Y+C N GE T +A L VE E
Sbjct: 3539 QNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPE 3583
Score = 38.9 bits (89), Expect = 0.045
Identities = 56/243 (23%), Positives = 87/243 (35%), Gaps = 50/243 (20%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 5159 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5207
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 5208 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5252
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 5253 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5289
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V S
Sbjct: 5290 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSST 5348
Query: 242 ASM 244
A +
Sbjct: 5349 AQL 5351
Score = 38.9 bits (89), Expect = 0.045
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
FA L V V E + RF C +T + V W KG ++ S + + +L I+
Sbjct: 5183 FAVPLKDVTVPERRQARFECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVIND 5240
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
DD GVYT V GK + SA L + G+
Sbjct: 5241 SQFDDEGVYTAEV---EGKKT-SARLFVTGI 5267
Score = 38.9 bits (89), Expect = 0.045
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11672
Query: 623 TYTCEAWNSAGEVRTQAVLTV 643
Y A NS+G + A++ V
Sbjct: 11673 KYIISAKNSSGHAQGSAIVNV 11693
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 1/124 (0%)
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 687
A N+ G + V E + P I P +T G+ + I + G P PT W +
Sbjct: 12570 ARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-K 12628
Query: 688 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
G+ + H V + + L++K V +G Y + +N G + ++ +++ ++
Sbjct: 12629 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12688
Query: 748 RALP 751
P
Sbjct: 12689 PPQP 12692
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 20975 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 21033
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 21034 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21067
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 21273 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21332
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
+NA+ +++ V L P PSKP PI
Sbjct: 21333 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21359
Score = 38.5 bits (88), Expect = 0.059
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1146 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 38.5 bits (88), Expect = 0.059
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 545 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 8787 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8845
Query: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+ GT+ L I++ +D G Y A NS G
Sbjct: 8846 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8878
Score = 38.5 bits (88), Expect = 0.059
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 11906 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11963
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 11964 SDGGKYVVTATNTAGS 11979
Score = 38.5 bits (88), Expect = 0.059
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 15843 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15901
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15956
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 15957 ---WG--PPKY 15962
Score = 38.5 bits (88), Expect = 0.059
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17327 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17385
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y +A N G
Sbjct: 17386 IDGGQYILRASNVAG 17400
Score = 38.5 bits (88), Expect = 0.059
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 22352 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22411
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 22412 RYFLTLENTAGVKTFSVTVVVIG 22434
Score = 38.1 bits (87), Expect = 0.078
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 472 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 8020 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 8063
Query: 531 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 589
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 8064 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8117
Query: 590 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 648
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 8118 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8175
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 702
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 8176 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8225
Query: 703 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
E+ + +K + P + + N+VG
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8255
Score = 37.7 bits (86), Expect = 0.10
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 551 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 603
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 9090 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9149
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
+ + L I + ED GTYT A N G V
Sbjct: 9150 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9181
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 15166 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15225
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 15226 AYTLTATNPGGFA 15238
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 18398 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18457
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 18458 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18493
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 548 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 594
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 19466 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19525
Query: 595 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+E L +++ DTG Y N AG
Sbjct: 19526 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19564
Score = 37.7 bits (86), Expect = 0.10
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 562 DLKVMDGSQVTMTV--------QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
DL + G+QVT+ + G P P + WL +G ++ESE F + + +L I
Sbjct: 21259 DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSI 21318
Query: 614 QEVFPEDTGTYT 625
+ E G YT
Sbjct: 21319 KNAKKEHGGKYT 21330
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 21665 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21724
Query: 1100 KCVAKNDAGQAECSCQVTVDDAP 1122
AKN +G A+ +V V D P
Sbjct: 21725 TVEAKNASGSAKAEIKVKVQDTP 21747
Score = 37.7 bits (86), Expect = 0.10
Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 8/188 (4%)
Query: 595 QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT---VQEPH-DG 649
Q+ DF E T Q + ++ + + + +A N AG + + ++EP +
Sbjct: 22281 QKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22340
Query: 650 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 709
T + +T G I I+G P P V W + L K+T + +D T
Sbjct: 22341 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTT 22399
Query: 710 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARAL-PRGREPASCED-LCGGGV 767
L +K +G+Y + L+N G + V++++ P S E + G
Sbjct: 22400 LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGE 22459
Query: 768 GADGGGSD 775
DGGG++
Sbjct: 22460 PKDGGGTE 22467
Score = 37.7 bits (86), Expect = 0.10
Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
GS T+ V +SG P P+V W ++E++ + +L +++ D+G Y
Sbjct: 22357 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22416
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
N+AG V+T +V V G ++ P V++ +S ++S
Sbjct: 22417 LENTAG-VKTFSVTVVVIGRPGP----VTGPIEVSSVSAESCVLS 22456
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1756
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8865
Query: 1757 DAKYTCKAVNSLGEATCTAELIV 1779
+Y A NS G A + V
Sbjct: 8866 HGRYVITATNSCGSKFAAARVEV 8888
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 6/123 (4%)
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ +A N+AG + A + + P I + G +V I I G PFPT+
Sbjct: 9784 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 9843
Query: 684 HWLR------DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 737
W + D K H L +D TLV+ + + G Y I N +G S +
Sbjct: 9844 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9903
Query: 738 VSL 740
+ L
Sbjct: 9904 MRL 9906
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11671
Query: 721 GQYEILLKNRVG 732
G+Y I KN G
Sbjct: 11672 GKYIISAKNSSG 11683
Score = 37.4 bits (85), Expect = 0.13
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 13005 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 13064
Query: 516 AENALGQVSCSAWVTVHEK 534
AEN+ G S + + V +K
Sbjct: 13065 AENSSGSKSATIKLKVLDK 13083
Score = 37.4 bits (85), Expect = 0.13
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 16233 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16284
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 16285 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16343
Query: 139 TLGDR 143
++
Sbjct: 16344 VTAEK 16348
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1671 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19862 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19920
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19921 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19971
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 20177 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20235
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 20236 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 21668 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21726
Query: 726 LLKNRVGECSCQVSLMLQNSSARAL 750
KN G ++ + +Q++ + +
Sbjct: 21727 EAKNASGSAKAEIKVKVQDTPGKVV 21751
Score = 37.0 bits (84), Expect = 0.17
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1009 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1068
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1126
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893
Query: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949
Query: 1187 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1221
EL K + IT +K RK+ + E + K +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009
Query: 1222 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1271
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1331
WY + IE D W E C ++D+ +
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101
Query: 1332 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1382
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161
Query: 1383 VTINTEQKVSDFY 1395
E D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 10234 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10291
Query: 628 AWNSAGEVRTQAVLTV 643
A N AGE + ++ V
Sbjct: 10292 AKNEAGERKKTIIVDV 10307
Score = 37.0 bits (84), Expect = 0.17
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1750
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11608 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11664
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA 1775
+ D KY A NS G A +A
Sbjct: 11665 EAVRADHGKYIISAKNSSGHAQGSA 11689
Score = 37.0 bits (84), Expect = 0.17
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1680 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1733
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11882 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11941
Query: 1734 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++ D + S ++ D KY A N+ G A + V
Sbjct: 11942 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 37.0 bits (84), Expect = 0.17
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 12603 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12662
Query: 623 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 654
Y+ A NS+G + + V + QP F
Sbjct: 12663 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12694
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16703
Query: 1758 AKYTCKAVNSLG 1769
KYT NS G
Sbjct: 16704 GKYTLTLENSSG 16715
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1689 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20623
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
S++I D + Y K N++G A+ T
Sbjct: 20624 SILIKDADRLNSGCYELKLRNAMGSASAT 20652
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 20577 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20636
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 20637 CYELKLRNAMGSA--SATIRVQILD 20659
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 6677 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6736
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 6737 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6781
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9881
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 9882 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9910
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 12311 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12369
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y+ +VN +G+ ++ + +
Sbjct: 12370 KYSLTLVNPAGEKAVFVNVRV 12390
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 574
A+N G +S + T + K EY P PT L + G + +
Sbjct: 14045 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14095
Query: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 14096 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14155
Query: 635 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
+TV + P IS + A+L
Sbjct: 14156 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14186
Score = 36.6 bits (83), Expect = 0.23
Identities = 18/66 (27%), Positives = 29/66 (43%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + VSG PPP + W +G E++ + + +L ++ D+G YT
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15230
Query: 628 AWNSAG 633
A N G
Sbjct: 15231 ATNPGG 15236
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 20183 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20242
Query: 625 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 656
A NS+G + ++ + P T P IS
Sbjct: 20243 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20275
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1674 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22326 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22384
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22385 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22432
Score = 36.2 bits (82), Expect = 0.29
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1007 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 5862 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5920
Query: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 5921 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5966
Score = 36.2 bits (82), Expect = 0.29
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 17329 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17387
Query: 720 AGQYEILLKNRVGECSCQVSL 740
GQY + N G S V++
Sbjct: 17388 GGQYILRASNVAGSKSFPVNV 17408
Score = 36.2 bits (82), Expect = 0.29
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 718
++VT G S+ + +++G P P + W + G L + E L++ KV +
Sbjct: 23149 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 23205
Query: 719 HAGQYEILLKNRVGECSCQV 738
AG+Y I +N+ G+ S V
Sbjct: 23206 DAGKYTIEAENQSGKKSATV 23225
Score = 35.8 bits (81), Expect = 0.38
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P T L V +EG + + IT + V W N + + + L I
Sbjct: 4435 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4492
Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
VN +D G Y C +N SGK + SA+L++
Sbjct: 4493 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4523
Score = 35.8 bits (81), Expect = 0.38
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 9046 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9090
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 9091 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9140
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 9141 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9200
Query: 261 VRETKA 266
V + KA
Sbjct: 9201 VTDIKA 9206
Score = 35.8 bits (81), Expect = 0.38
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 11220 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11278
Query: 726 LLKNRVGECSCQVSL 740
+ N G + V L
Sbjct: 11279 TVSNAAGSKTVAVHL 11293
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 14069 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14128
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 14129 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14164
Score = 35.8 bits (81), Expect = 0.38
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 16649 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16705
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 16706 YTLTLENSSGTKSAFVTVRV 16725
Score = 35.8 bits (81), Expect = 0.38
Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + + SL
Sbjct: 19090 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSS-KTVTSLS 19148
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 19149 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19177
Score = 35.8 bits (81), Expect = 0.38
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1713 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 21047
Score = 35.8 bits (81), Expect = 0.38
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1073
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 27010 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27069
Query: 1074 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ L ++ I +D GLY N+ G + + +
Sbjct: 27070 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115
Score = 35.4 bits (80), Expect = 0.50
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 6160 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6218
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1150
A ED G Y C R P S +D
Sbjct: 6219 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6237
Query: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 6238 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6287
Query: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 6288 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6334
Score = 35.4 bits (80), Expect = 0.50
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 10522 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10581
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 10582 GKYCVVVENSTGSRKGFCQVNV 10603
Score = 35.4 bits (80), Expect = 0.50
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 607
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 11895 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11952
Query: 608 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+ + D G Y A N+AG A + V
Sbjct: 11953 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 35.4 bits (80), Expect = 0.50
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 571
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 17288 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17338
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 17339 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17398
Query: 632 AG 633
AG
Sbjct: 17399 AG 17400
Score = 35.4 bits (80), Expect = 0.50
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---E 493
G V+++ ++ V+K A G L+ + G P P I W + + +Q C
Sbjct: 20563 GGPVIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENT 20619
Query: 494 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
+A + I+DA + G Y NA+G S + V + +K
Sbjct: 20620 TDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20660
Score = 35.4 bits (80), Expect = 0.50
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 23841 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23898
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 23899 TYDLVLENKCGKKAVYIKVRVIG 23921
Score = 35.4 bits (80), Expect = 0.50
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1747
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26069 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26126
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
I D DD Y N GEA+ A L V
Sbjct: 26127 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5537 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5594
Query: 1751 DVCGDDDAKYTCKA 1764
+D+AKY +A
Sbjct: 5595 SAAFEDEAKYMFEA 5608
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10285
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 10286 GVYSLLAKNEAGE 10298
Score = 35.0 bits (79), Expect = 0.66
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 12313 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12368
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 12369 GKYSLTLVNPAGEKAVFVNVRV 12390
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 13000 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 13058
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
YT A NS G + T +L V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080
Score = 35.0 bits (79), Expect = 0.66
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 546 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 13667 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13726
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 652
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 13727 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13777
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 14066 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14115
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 14116 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14154
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 20180 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20238
Query: 720 AGQYEILLKNRVGECSCQVSLML 742
AG+YEI N G +++++
Sbjct: 20239 AGRYEITAANSSGTTKAFINIVV 20261
Score = 34.7 bits (78), Expect = 0.86
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 623 TYTCEAWNSAGE----VRTQAVLTVQEPHDGTQPWFISKP---------RSVTASLGQSV 669
TYT + E VR + + EP T P P S+ G +
Sbjct: 8333 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEI 8392
Query: 670 LISCAIAGDPFPTVHWLRD 688
+ +I+G P+PT+ W++D
Sbjct: 8393 ALDASISGSPYPTITWIKD 8411
Score = 34.7 bits (78), Expect = 0.86
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 16253 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16312
Query: 628 AWNSAGE 634
A N AGE
Sbjct: 16313 AKNVAGE 16319
Score = 34.7 bits (78), Expect = 0.86
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 18814 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18869
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 18870 RYNLTLENNSGSKTAFVNVRV 18890
Score = 34.7 bits (78), Expect = 0.86
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19088 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19146
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + +D Y NS G T +IV
Sbjct: 19147 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6341 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6398
Query: 1755 DDDAKYTCKAVNSLGE-ATCTAELIVE 1780
DD A Y N GE A LIVE
Sbjct: 6399 DDQANYNVSLTNHRGENVKSAANLIVE 6425
Score = 34.3 bits (77), Expect = 1.1
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 7054 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7111
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 7112 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7166
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 11904 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11963
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 11964 SDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1692 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1751
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17723 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17778
Query: 1752 VCGDDDA-KYTCKAVNSLG 1769
C +DA KY K NS G
Sbjct: 17779 NCDRNDAGKYILKLENSSG 17797
Score = 34.3 bits (77), Expect = 1.1
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 23817 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23874
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 23875 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23922
Score = 33.9 bits (76), Expect = 1.5
Identities = 51/246 (20%), Positives = 95/246 (38%), Gaps = 41/246 (16%)
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPE 507
L+D E Q+ V + + + + + W + I+ + + + +L + + + +
Sbjct: 2493 LRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKD 2551
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 567
D G YT A G+ S +TV A SKP L+D V +
Sbjct: 2552 DEGKYTFYA----GENMTSGKLTVAGG------------AISKP--------LTDQTVAE 2587
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
+ +V+ NP + WL +G + + + E G + L I +D G YT +
Sbjct: 2588 SQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYK 2646
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWL 686
S +T A L V+ I K +++T + Q + + + V W+
Sbjct: 2647 VATS----KTSAKLKVEAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWI 2695
Query: 687 RDGKAL 692
++G L
Sbjct: 2696 KNGVVL 2701
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10285
Query: 721 GQYEILLKNRVGE 733
G Y +L KN GE
Sbjct: 10286 GVYSLLAKNEAGE 10298
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15171 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15229
Query: 1763 KAVNSLGEA 1771
A N G A
Sbjct: 15230 TATNPGGFA 15238
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 15536 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15593
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 15594 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15643
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 16647 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16704
Query: 623 TYTCEAWNSAG 633
YT NS+G
Sbjct: 16705 KYTLTLENSSG 16715
Score = 33.9 bits (76), Expect = 1.5
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+ + I + G P P + W++DG+ L K T V + L +K+ G+Y +
Sbjct: 18021 GEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 18079
Query: 726 LLKNRVGECSCQVSLML 742
N G + +S+++
Sbjct: 18080 TATNSAGTATENLSVIV 18096
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 21242 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21301
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 21302 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21346
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCL 515
G F + + G P P++TW L ++ T L ++D++ D G Y
Sbjct: 22357 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22416
Query: 516 AENALGQVSCSAWVTV 531
EN G + S V V
Sbjct: 22417 LENTAGVKTFSVTVVV 22432
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1676 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1725
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23123 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23177
Query: 1726 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23178 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23224
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5271 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5328
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+V DD ++ + + E + TA+L V
Sbjct: 5329 EVTLDDISQIKAQ----VKELSSTAQLKV 5353
Score = 33.5 bits (75), Expect = 1.9
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5626 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5683
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCT 1774
D+ DD ++ +A+ EA T
Sbjct: 5684 DLSIDDTSQIRVEAMGMSSEAKLT 5707
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 7114 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7173
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 7174 EIDVNVIARPSA 7185
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 8067 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8118
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 8119 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8173
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 513
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 11911 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11970
Query: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
A N G A V V +K ++ ++ V+ + T
Sbjct: 11971 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 12009
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 13396 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13451
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 13452 NKYDAGKYILTLENSCGKKEYTIVVKV 13478
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 15168 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15226
Query: 104 YTCEATNGSG 113
YT ATN G
Sbjct: 15227 YTLTATNPGG 15236
Score = 33.5 bits (75), Expect = 1.9
Identities = 33/148 (22%), Positives = 53/148 (35%), Gaps = 5/148 (3%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 19494 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19552
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 19553 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19612
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKIT 185
K T + EG++ SCK+T
Sbjct: 19613 YIVEKRETSHLAWTICEGELQMTSCKVT 19640
Score = 33.5 bits (75), Expect = 1.9
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 19852 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19909
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 19910 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19966
Query: 121 LTV 123
+ V
Sbjct: 19967 VKV 19969
Score = 33.5 bits (75), Expect = 1.9
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 503
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19941
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTV 531
A D G YT +N L S + V V
Sbjct: 19942 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19969
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 19891 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19948
Query: 623 TYTCEAWN 630
YT N
Sbjct: 19949 KYTLTIQN 19956
Score = 33.1 bits (74), Expect = 2.5
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653
Query: 242 ASMSAE 247
A + E
Sbjct: 2654 AKLKVE 2659
Score = 33.1 bits (74), Expect = 2.5
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1656 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1701
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5311 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5370
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5371 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5427
Query: 1762 CKAVNSLGEATCTAE 1776
C +A T E
Sbjct: 5428 CDCGTDKTKANVTVE 5442
Score = 33.1 bits (74), Expect = 2.5
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1091
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 9103 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9162
Query: 1092 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
+ ED+G Y A N G + V V D P+
Sbjct: 9163 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9194
Score = 33.1 bits (74), Expect = 2.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10921 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10977
Query: 1756 DDAKYTCKAVNSLGEATCTAELIV 1779
D Y+ N G T + +++V
Sbjct: 10978 DGGIYSLTVENPAGSKTVSVKVLV 11001
Score = 33.1 bits (74), Expect = 2.5
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 506
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19549
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 19550 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19591
Score = 33.1 bits (74), Expect = 2.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG 113
+G P P VTW ++ + + S R+ ++ + L I V D GKY NG G
Sbjct: 20991 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVG 21046
Score = 33.1 bits (74), Expect = 2.5
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 22064 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22119
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 22120 KYTLTVENNSGSKSITFTVKV 22140
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 1755 DDDAKYTCKAVNSLGEAT 1772
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1094
G ++ + + P W +GK K K + L + + I +
Sbjct: 9520 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9579
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
G Y AKN AGQ +C+V V D P
Sbjct: 9580 HTGKYSITAKNKAGQKTANCRVKVMDVP 9607
Score = 32.7 bits (73), Expect = 3.3
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1761
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22757 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22814
Query: 1762 CKAVNSLG 1769
N+ G
Sbjct: 22815 LTVKNASG 22822
Score = 32.3 bits (72), Expect = 4.3
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1696 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1753
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6254 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6309
Query: 1754 GDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y V +G A A L V
Sbjct: 6310 LQDMGTY----VVMVGAARAAAHLTV 6331
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 545 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 10503 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10562
Query: 603 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 633
+ T +L ++++ + D+G Y NS G
Sbjct: 10563 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10593
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
I G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 13701 IKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13759
Query: 735 SCQVSL 740
+S+
Sbjct: 13760 EGTISI 13765
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 506
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 15163 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15221
Query: 507 EDHGTYTCLAENALG 521
D G YT A N G
Sbjct: 15222 RDSGAYTLTATNPGG 15236
Score = 32.3 bits (72), Expect = 4.3
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 515
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 20186 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20245
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 566
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 20246 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20292
Query: 567 DGSQVT 572
GSQVT
Sbjct: 20293 GGSQVT 20298
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20624
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
+ I++ ++G Y + N+ G A + VQ
Sbjct: 20625 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20656
Score = 32.3 bits (72), Expect = 4.3
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 23438 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23496
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 23497 TIRDTGEYTLELKNVTGTTSETIKVII 23523
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1691 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1625 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1677
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1750
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12361
Query: 1751 DVCGDDDAKYTCKAVNSLGE 1770
+ DD KY+ VN GE
Sbjct: 12362 NSTRDDSGKYSLTLVNPAGE 12381
Score = 32.0 bits (71), Expect = 5.6
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 717
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14534
Query: 718 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 750
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 14535 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14567
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18468
Query: 1755 DDDAKYTCKAVN 1766
D +Y K N
Sbjct: 18469 TDGGQYILKLSN 18480
Score = 32.0 bits (71), Expect = 5.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 22355 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22413
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 22414 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22465
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 22466 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22518
Score = 31.6 bits (70), Expect = 7.3
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13749
Query: 1762 CKAVNSLG--EATCTAELI 1778
N G E T + +++
Sbjct: 13750 ITLKNVAGTKEGTISIKVV 13768
Score = 31.6 bits (70), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAE--LHIQDALPEDHGTYTC 514
E +F L+ ++G P P ++W P+ R + E+ L + D D G YT
Sbjct: 13691 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13750
Query: 515 LAENALG 521
+N G
Sbjct: 13751 TLKNVAG 13757
Score = 31.6 bits (70), Expect = 7.3
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 625
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 18417 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18475
Query: 626 CEAWNSAG 633
+ N G
Sbjct: 18476 LKLSNVGG 18483
Score = 31.2 bits (69), Expect = 9.5
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 1664 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1710
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4397 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4456
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1769
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4457 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4513
Query: 1770 EATCTAELIV 1779
+ +A+L V
Sbjct: 4514 KTATSAKLTV 4523
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1007 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1066
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 6228 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6283
Query: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 6284 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6331
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALP 506
+L V G L +V G P P+ITW + Q R T E + + I D+
Sbjct: 7391 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 7450
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEK 534
D GTY A N G+ + V V +K
Sbjct: 7451 SDTGTYIIEAVNVCGRATAVVEVNVLDK 7478
Score = 31.2 bits (69), Expect = 9.5
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 10/79 (12%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLL-------NGQPIQYARSTCEAGVAE---LHIQDAL 505
V EG + + ++G P P +TW N +P+ Y + V + L I +
Sbjct: 9823 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9882
Query: 506 PEDHGTYTCLAENALGQVS 524
D G YT A N LG S
Sbjct: 9883 RSDTGLYTITAVNNLGTAS 9901
Score = 31.2 bits (69), Expect = 9.5
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14479 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14535
Query: 1756 DDAKYTCKAVNSLGE 1770
D K+ N G+
Sbjct: 14536 DTGKFVMTIENPAGK 14550
Score = 31.2 bits (69), Expect = 9.5
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 14481 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14532
Query: 617 FPEDTGTYTCEAWNSAGE 634
DTG + N AG+
Sbjct: 14533 NRYDTGKFVMTIENPAGK 14550
Score = 31.2 bits (69), Expect = 9.5
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1761
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14775 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14832
Query: 1762 CKAVNSLGE 1770
A N +GE
Sbjct: 14833 LTARNIVGE 14841
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 15165 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15223
Query: 720 AGQYEILLKNRVG 732
+G Y + N G
Sbjct: 15224 SGAYTLTATNPGG 15236
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19491 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19549
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y N G
Sbjct: 19550 RDTGQYVLTLKNVAG 19564
Score = 31.2 bits (69), Expect = 9.5
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 20181 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20240
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 20241 RYEITAANSSG 20251
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1761
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22067 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22122
Query: 1762 CKAVNSLGEATCT 1774
N+ G + T
Sbjct: 22123 LTVENNSGSKSIT 22135
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 514
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 23843 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23902
Query: 515 LAENALGQ 522
+ EN G+
Sbjct: 23903 VLENKCGK 23910
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1085
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ I +D +Y+ A N G + + V+
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24648
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
P K +P + +R GE V + +G TW K
Sbjct: 24649 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24692
Query: 1206 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 24693 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24752
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1324
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 24753 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24811
Query: 1325 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1384
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 24812 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24868
Query: 1385 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1444
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 24869 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24927
Query: 1445 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1504
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 24928 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24987
Query: 1505 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1564
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 24988 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 25047
Query: 1565 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1585
++ + ATDMWS+G + Y+L
Sbjct: 25048 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 25107
Query: 1586 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1633
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 25108 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25166
Query: 1634 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1693
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 25167 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25214
Query: 1694 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 25215 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25259
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
DD Y CK VN GE + AEL V+ + E
Sbjct: 25260 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25291
Score = 166 bits (420), Expect = 2e-40
Identities = 161/707 (22%), Positives = 277/707 (39%), Gaps = 57/707 (8%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 26376 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26435
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 26436 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26490
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 26491 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26550
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
TC V N +G S S +L+I+ + V K S++ + V+ +E + A
Sbjct: 26551 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQK--TSEITPQKKAVVQEEIS----QKA 26604
Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK--TSSSITLQA 349
+S+ + A + S E K S T+ + ++ + T +S +
Sbjct: 26605 LRSEEIKMSEAKSQEKLALKEEASKVLIS--EEVKKSAATSLEKSIVHEEITKTSQASEE 26662
Query: 350 ARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT---FPTRQPGLGSQD-----VVSKAANR 401
R E +A + G+ A AT + L + + V
Sbjct: 26663 VRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTL 26722
Query: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQD 461
I RD SK + VK + E + AP+F S + + EGQ+
Sbjct: 26723 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE----LSDAPAFISQPRSQNINEGQN 26778
Query: 462 FVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAEN 518
+ C + G P P I W N PI + + V L I++A D G YT A+N
Sbjct: 26779 VLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 26838
Query: 519 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
GQ S +A S +LP+ +P+ + L+ D + GS + +VQ+S
Sbjct: 26839 FRGQCSATA------------SLMVLPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMS 26884
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 638
+ + + + F Q +QE F E + + N ++ +
Sbjct: 26885 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESS 26943
Query: 639 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTG 697
++ G P + P ++ G+ + ++CA G+P P V W G+ + ++ G
Sbjct: 26944 TSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQG 27003
Query: 698 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 744
F + +D+ TL++ VQ G Y + L N G S V++ +++
Sbjct: 27004 RFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 27050
Score = 144 bits (364), Expect = 6e-34
Identities = 155/657 (23%), Positives = 238/657 (36%), Gaps = 132/657 (20%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP+ +L V V+ G+ RF I+GRPQP+++W K L + L
Sbjct: 3192 PPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLL 3251
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
+ +D VYTC N G A+ T++ + EV V+
Sbjct: 3252 LIEAFPEDAAVYTCEAKNDYGVAT-----------------------TSASLSVEVPEVV 3288
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ 339
S + ++ A + + G P A Q + S + + +
Sbjct: 3289 SPDQEMPVYPPAIITPLQDTVTSEGQP---ARFQCRVSGTDLKVSWYSKDKKIKPSRFFR 3345
Query: 340 KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAA 399
T T Q + P G S + VS A
Sbjct: 3346 MTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQ----------------------VSSTA 3383
Query: 400 NRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEG 459
N + +EG F KFE + + + +V F+ E L PSF L V G
Sbjct: 3384 N--LSLEG-----FSKFEENTSNSQWHVSLSVSFKKEPLGQK---PSFIQPLSSLRVHNG 3433
Query: 460 QDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC-----EAGVAELHIQDALPEDHGTYTC 514
+ V G P P I W N Q I + G+A + I DA E G Y+C
Sbjct: 3434 ETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSC 3493
Query: 515 LAENALGQVSCSAWVTV---------HEK-----------------------------KS 536
A N+ G+ +C+A +TV HE+ +
Sbjct: 3494 KAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQL 3553
Query: 537 SRKSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 585
S+ +E L PV P+K T PIF++ +S+ + G T++V V G P P++
Sbjct: 3554 SKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKI 3613
Query: 586 IWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ- 644
W NG + S D+ F G HSL I ED G YTC A N G+ A L +
Sbjct: 3614 QWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3673
Query: 645 --EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 685
E H T+ P F+ + + + + G + + G+P PTV W
Sbjct: 3674 KGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTW 3733
Query: 686 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 742
++ K LC + + T ++ Q +G Y +N +GE +C L++
Sbjct: 3734 FKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 132 bits (333), Expect = 2e-30
Identities = 177/693 (25%), Positives = 282/693 (40%), Gaps = 114/693 (16%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSL 288
G YT + +G +A+L ++G D RS ++KEV VI K+ +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRS-----------IKKEV-QVIEKQRAVVEF 3122
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR----TAPQTPVLQKTSSS 344
E + + G + + + E ++ S T V + SS
Sbjct: 3123 EVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSS 3182
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG---SQDVVSKAANR 401
+TL +P P+ L L P + +PA QP + + ++S
Sbjct: 3183 VTLYVNAPEP-PQV--LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239
Query: 402 RIPMEGQRDS-----AFPKFESKPQSQEVKENQTVKFRCEGLAVM--EVA---------- 444
+ +GQ + AFP+ ++ + E K + V L+V EV
Sbjct: 3240 KFLHDGQEYTLLLIEAFPE-DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3298
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHI 501
P+ + L+D EGQ QC V GT + +++W + P ++ R T +L I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAPSKPTA-- 553
+A PED GTYT +A NA+GQVS +A +++ E S+ + L V+ K
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQ 3417
Query: 554 -PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHS 610
P F+Q LS L+V +G V +VSG P PE+ W HN I ++D FHFE+
Sbjct: 3418 KPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMAL 3477
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+ I + + E G Y+C+A NSAGE A LTV
Sbjct: 3478 MLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 132 bits (332), Expect = 3e-30
Identities = 155/680 (22%), Positives = 250/680 (36%), Gaps = 97/680 (14%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376
Query: 240 GKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKE---------SKLDSLEA 290
G+ S +A LS++G E +NS ++ KE L SL
Sbjct: 3377 GQVSSTANLSLEGFSKF------EENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRV 3430
Query: 291 AAKSKNCSSPQRGGSP----PWAANSQPQPPRESKLESCKDS------------PRTAPQ 334
+ G P W N Q P + + ++S A Q
Sbjct: 3431 HNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQ 3490
Query: 335 TPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQD 393
S+ AA + P+AP + +E + ++F + GL S +
Sbjct: 3491 YSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAE 3550
Query: 394 VVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKD 453
+ N + + + KF+S+ + P F + +
Sbjct: 3551 LQLSKINETLELLSESPVYPTKFDSEKEG--------------------TGPIFIKEVSN 3590
Query: 454 CAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHG 510
+ G L +V G P P+I W NG P + + L I ED G
Sbjct: 3591 ADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEG 3650
Query: 511 TYTCLAENALGQVSCSAWVTVHEKKSSRK-SEYLLPVAPS-----KPTAPIFLQGLSDLK 564
YTC+A N G+ CSA++ ++ K K +E VA S P P FL+ L ++
Sbjct: 3651 EYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR 3710
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH-FEQRGTQHSLCIQEVFPEDTGT 623
G V G P P V W ++ S + + + + ED+G
Sbjct: 3711 CAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGL 3770
Query: 624 YTCEAWNSAGEVRTQAVLTV 643
Y C+A N GE A L V
Sbjct: 3771 YICKAENMLGESTCAAELLV 3790
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 23779 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23835
Query: 726 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 779
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 23836 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23891
Query: 780 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 837
+ W + VRG +++ E R Q L + V+
Sbjct: 23892 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23949
Query: 838 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 894
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 23950 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 24008
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 953
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 24009 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 24064
Query: 954 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1001
L+ + +K + TL KP K D K ++KE +K
Sbjct: 24065 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 24124
Query: 1002 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 24125 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24183
Query: 1052 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1111
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 24184 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24243
Query: 1112 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
S ++ + P P P K
Sbjct: 24244 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24263
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1230
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 24264 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24319
Query: 1231 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 24320 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24379
Query: 1291 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 24380 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24439
Query: 1349 ESELTTVGEKPEEP 1362
S + + E+P
Sbjct: 24440 VSSVVIIKSPFEKP 24453
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 645
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 646 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 691 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 748 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 806
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 807 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 863
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242
Query: 864 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 912
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 913 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 966
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350
Query: 967 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1026
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407
Query: 1027 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1083
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467
Query: 1084 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1143
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504
Query: 1144 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1203
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544
Query: 1204 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1258
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604
Query: 1259 VDKPDP------PAGTPCASDIRSSSL 1279
+P+P P GT A +I + L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 25981 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 26040
Query: 593 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 613
E+QES D H + GT ++C
Sbjct: 26041 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 26100
Query: 614 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 649
+ VFPE T T EA +S EV++Q T + H
Sbjct: 26101 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26160
Query: 650 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 26161 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26220
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 26221 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279
Query: 744 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 779
+ + ++ R + P +++
Sbjct: 26280 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26339
Query: 780 LRPGWPARGQGWLEEEDGEDVR--------GVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 26340 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399
Query: 832 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 885
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459
Query: 886 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 914
S + +K K P P P P+P T D ++
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26519
Query: 915 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 946
+ GGK KL + G SS+ L KA++ ++
Sbjct: 26520 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26579
Query: 947 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 998
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 26580 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26636
Query: 999 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 26637 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26694
Query: 1059 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 26695 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754
Query: 1119 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178
+ E+ SDA P I P Q
Sbjct: 26755 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26771
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 26772 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26831
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 26832 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26891
Query: 1299 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1354
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 26892 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26949
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEV 1378
G + PK E SD E +V
Sbjct: 26950 AGIRGIPPKIEALPSDISIDEGKV 26973
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 12526 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12584
Query: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1286
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 12585 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12644
Query: 1287 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 12645 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12704
Query: 1346 PSQESELTTVGE--KPEEPKD 1364
P ++ P EPK+
Sbjct: 12705 PLTSPKMVAQFPFGVPSEPKN 12725
Score = 110 bits (276), Expect = 9e-24
Identities = 154/692 (22%), Positives = 268/692 (38%), Gaps = 99/692 (14%)
Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
+V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG +
Sbjct: 4396 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4452
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+LTV A PV+ + K+ + V G + +
Sbjct: 4453 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4480
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F+C+I P + W K + S + S+ + LEI D G YTC N
Sbjct: 4481 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4540
Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
G S +A L ++ G + R + E K + ++EV +V+ K + + + K
Sbjct: 4541 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4597
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
+ P PP P+P E ++ + R P+ + + +I L A +P
Sbjct: 4598 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4651
Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
+P A + P E P P T P ++ +AA + P++G
Sbjct: 4652 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4710
Query: 415 KFES-----KPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE----GQDFVLQ 465
E+ +P S K F + + V F +KD + E G + +
Sbjct: 4711 PIEAERRKLRPGSGGEKPPDEAPFTYQ---LKAVPLKFVKEIKDIILTESEFVGSSAIFE 4767
Query: 466 CSVRGTPVPRI-TWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALG 521
C V +P I TW+ +G I+ + R + +LHI D D G YTC+
Sbjct: 4768 CLV--SPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 4825
Query: 522 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGN 580
+ + +A + V E LPV F++ L ++ V+ G + ++ ++ N
Sbjct: 4826 EKTSTAKLVVEE----------LPVR--------FVKTLEEEVTVVKGQPLYLSCEL--N 4865
Query: 581 PPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 639
+V+W +G + E G +L I + D GTYT N+ +
Sbjct: 4866 KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSC 4925
Query: 640 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGH 698
V V+ D W + R + + +C IA D P + W + + +
Sbjct: 4926 VKVVEVIRD----WLVKPIRDQHVKPKGTAIFACDIAKDT-PNIKWFKGYDEIPAEPNDK 4980
Query: 699 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
E+L++ + L +K P +Y + ++ +
Sbjct: 4981 TEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 5012
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 498
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQ 644
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 7330 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7389
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 7390 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7448
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1357
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 7449 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7508
Query: 1358 KPEEPKDEVEVSD 1370
P P +E SD
Sbjct: 7509 DPPGPPTRLEPSD 7521
Score = 107 bits (266), Expect = 1e-22
Identities = 159/700 (22%), Positives = 240/700 (34%), Gaps = 154/700 (22%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
K ++ P F+ K S +K F C +
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPI--------------- 1683
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512
G P + WL +G+P++ A R E G L A D G
Sbjct: 1684 --------------GDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGII 1729
Query: 513 TCLAENALGQVSCSAWVTVHEKKSSRKSEYL------------------------LPVAP 548
TC A N G SA + V ++KS + L +
Sbjct: 1730 TCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQ 1789
Query: 549 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 608
+ P + ++V++G +V+G P P+V W NG I++S+ F G
Sbjct: 1790 KEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI- 1848
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
H L I + DTG A N G + + L +Q+ D
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 102 bits (253), Expect = 4e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 20504 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20563
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 20564 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20623
Query: 1292 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 20624 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20680
Query: 1348 QESEL 1352
+ +
Sbjct: 20681 ESDSV 20685
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1167 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 11134 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11193
Query: 1224 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1283
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 11194 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11253
Query: 1284 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1342
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 11254 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11313
Query: 1343 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1400
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 11314 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11371
Query: 1401 LGSGKFGQV 1409
+GK+ +V
Sbjct: 11372 EVTGKWVRV 11380
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 16168 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16224
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 16225 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16284
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16344
Query: 1341 YGTSEPSQESELTTVGE--KPEEPK 1363
YG EP + + P+ PK
Sbjct: 16345 YGVGEPLESEPVVAKNPFVVPDAPK 16369
Score = 101 bits (251), Expect = 7e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1174 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1233
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 21991 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 22048
Query: 1234 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1293
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 22049 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 22107
Query: 1294 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1352
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 22108 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22167
Query: 1353 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1402
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22226
Query: 1403 SGKFGQVFRLVEK 1415
V RLVEK
Sbjct: 22227 KQLTFTVERLVEK 22239
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 15093 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15152
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 15153 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15212
Query: 1292 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 15213 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15272
Query: 1351 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1402
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 15273 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15322
Query: 1403 SGKFGQVFRLVEKKT 1417
K GQ + KKT
Sbjct: 15323 -DKAGQRWIKCNKKT 15336
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 15787 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15846
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 15847 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15906
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 15907 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15952
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 554
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362
Query: 555 -------------------------------------------------IFLQGLSDLKV 565
+F+ K
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 684 HWLRD 688
WL++
Sbjct: 1542 VWLKN 1546
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1219
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 9744 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9802
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1279
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 9803 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9862
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1338
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 9863 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9922
Query: 1339 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 9923 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9971
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 17251 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17307
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1282
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 17308 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17367
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1341
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 17368 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17427
Query: 1342 GTSEPSQES 1350
G EP + +
Sbjct: 17428 GVGEPLESA 17436
Score = 99.0 bits (245), Expect = 4e-20
Identities = 98/385 (25%), Positives = 150/385 (38%), Gaps = 54/385 (14%)
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
R SP + + P E E+ A L TSS A ++ +AP
Sbjct: 764 RTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSS-----AQKITKSVKAP-- 816
Query: 362 GVLSPSGEERKRPAPPRPATFP------TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
+ PS E R R P FP T + G + V K I R+ F
Sbjct: 817 -TVKPS-ETRVRAEPTPLPQFPFADTPDTYKSEAGVE--VKKEVGVSITGTTVREERFEV 872
Query: 416 FESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 475
+ E K +T + + + P+ S LK+ VIEG+ L+C + G P P
Sbjct: 873 LHGR----EAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 927
Query: 476 ITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
+TW I+ + + T ++G+A L I++A ED G +TC A N G VS S ++ V
Sbjct: 928 VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Query: 533 -----EKKSSRKSEYLLP----------------------VAPSKPTAPIFLQGLSDLKV 565
EK+++ +E P +P AP F+ K+
Sbjct: 988 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKL 1047
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQRGTQHSLCIQEVFPEDTGT 623
++G V QV GNP P V W +G + + + ++ + L I F +D G
Sbjct: 1048 VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHD 648
YT N GE A L + ++
Sbjct: 1108 YTIVVRNKHGETSASASLLEEADYE 1132
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 21203 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21262
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 21263 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21322
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21323 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21370
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 13053
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 13054 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 13101
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1159 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1277
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1336
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 10556 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10615
Query: 1337 AINVYGTSEPSQESELTT-----VGEKPEEP 1362
A N+YG S+P + V + P++P
Sbjct: 10616 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10646
Score = 95.9 bits (237), Expect = 3e-19
Identities = 158/697 (22%), Positives = 252/697 (36%), Gaps = 128/697 (18%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ-MGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN-VKTTAKLIVEG---AVVE 2222
Query: 260 FVRETKATN--SDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAP---GLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423
G+E QP V+ K ++ + + ++ A
Sbjct: 2342 WMKDGQEV--------------QPSDRVHIVIDKQSHMLLIEDMTKEDA----------- 2376
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFS----SVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 479
N + GL+ +S + LKD VIEG VL+C V V + W
Sbjct: 2377 ---GNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWY 2433
Query: 480 LNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
LN + I+ ++ + L I D G Y + +G+V + ++V + K
Sbjct: 2434 LNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLI----VGRVETNCNLSVEKIK- 2488
Query: 537 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
++GL DL + V V++S + +V+W EI+
Sbjct: 2489 -------------------IIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKP 2528
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
S + E G + L + + +D G YT AGE T LTV IS
Sbjct: 2529 SSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAGENMTSGKLTV-------AGGAIS 2577
Query: 657 KP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
KP T + Q + C +A +P WLRDGK L
Sbjct: 2578 KPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHL 2613
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+G + + + K P P I D V GE + + T +W K
Sbjct: 7994 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 8110
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1323
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 8111 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8169
Query: 1324 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1380
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 8170 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8228
Query: 1381 RTVTINTEQKVSDFYDIEERLGSGK 1405
+ + K+ + I E++ G+
Sbjct: 8229 KPPLYDGGSKIMGY--IIEKIAKGE 8251
Score = 95.9 bits (237), Expect = 3e-19
Identities = 64/229 (27%), Positives = 117/229 (51%), Gaps = 20/229 (8%)
Query: 531 VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 588
VHE+ K+S+ SE + A K + + + + +G ++ + ++G +V W+
Sbjct: 26649 VHEEITKTSQASEEVRTHAEIKAFS-------TQMSINEGQRLVLKANIAG--ATDVKWV 26699
Query: 589 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
NG E+ SE++ + G+ +L I++ D G TC + G V+ Q LT+ +
Sbjct: 26700 LNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS 26759
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
P FIS+PRS + GQ+VL +C I+G+P P + W ++ + + + + ++ +V+
Sbjct: 26760 DA-PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVY 26817
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757
+L ++ +G+Y I KN G+CS SLM+ LP EP+
Sbjct: 26818 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-------LPLVEEPS 26859
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1180 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 14018 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 14077
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 14078 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14136
Query: 1299 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 14137 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14193
Query: 1355 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 14194 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14226
Score = 95.5 bits (236), Expect = 4e-19
Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 29/293 (9%)
Query: 475 RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++TW + ++ + T E GVA L+++D D GTY C N G+ S A + V
Sbjct: 25227 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Query: 532 HE-------------KKSSRKSEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 577
KK R+++ + L P + T P++ + G V V +
Sbjct: 25287 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTI 25341
Query: 578 SGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ +P P V W +G +I+ ++ + FE + L I V +D YT A N GE
Sbjct: 25342 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25401
Query: 635 VRTQAVLTVQ---EPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
+A LTV P D T +P F + GQSV ++G P PT+ W +DG+
Sbjct: 25402 DSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 25461
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
L + + D + L ++ P G Y + N G SCQ L ++
Sbjct: 25462 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 14416 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14473
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 14474 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14532
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 14533 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14592
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1409
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 14593 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14642
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 19414 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19470
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 19471 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19530
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 19531 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19590
Query: 1341 YGTSEP 1346
YG EP
Sbjct: 19591 YGVGEP 19596
Score = 94.7 bits (234), Expect = 7e-19
Identities = 131/586 (22%), Positives = 204/586 (34%), Gaps = 111/586 (18%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 26061
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN----------------------- 257
+ DD G Y + N G+AS A L + G D
Sbjct: 26062 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 26121
Query: 258 --------------RSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQR 302
S VRE K+ ++ R+ +++ S +++ S KS S R
Sbjct: 26122 YAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTR 26181
Query: 303 GGSPPWAANSQPQPPR------ESKLESCKDSPRTAPQTPVLQK--------------TS 342
AA +P ES SC P L+K T
Sbjct: 26182 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 26241
Query: 343 SSITLQAARVQPEPRAPGLGVLSPS-GEE--------RKRPAPPRPATFPTR----QPGL 389
T + + VQ V+ S G++ +K + T P R +P +
Sbjct: 26242 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRV 26301
Query: 390 GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSS 449
S + V + P E A E+KP E ++ V P +
Sbjct: 26302 KSPEAVKSPKRVKSP-EPSHPKAVSPTETKPTPTEKVQHLPVS----------APPKITQ 26350
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEAGVAELHIQD 503
LK A + L C V + + +TW +G+ ++ + G EL I +
Sbjct: 26351 FLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINN 26408
Query: 504 ALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKSEYLLPVAPS 549
D G Y C G Q A+ ++HEK KS +K+ +
Sbjct: 26409 LTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT 26468
Query: 550 KPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
+P AP + + GL D V S V+ +G P P IW +G I + +
Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
+ L I + D+G YTC NSAG V + LT++ D
Sbjct: 26529 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26574
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 23086 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23143
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 23144 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23202
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 23203 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23262
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P P ++EV D V TVT+ E+ + D
Sbjct: 23263 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23289
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 19034 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 19093
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 19094 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19152
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 19153 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19210
Query: 1359 PEEP 1362
P P
Sbjct: 19211 PFSP 19214
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1181 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1232
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 9451 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9510
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9569
Query: 1293 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 9570 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9629
Query: 1352 LTTVGEK--PEEPKDEVEV 1368
TT + P +P ++++
Sbjct: 9630 RTTARDPIYPPDPPIKLKI 9648
Score = 92.8 bits (229), Expect = 3e-18
Identities = 81/311 (26%), Positives = 120/311 (38%), Gaps = 37/311 (11%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQD 503
S+ K+ VIE Q V++ V V W +G I + + E + + I +
Sbjct: 3105 SIKKEVQVIEKQRAVVEFEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISE 3163
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 563
D G YT +A +R S L AP P LQ L +
Sbjct: 3164 TRQSDAGEYTFVAGR------------------NRSSVTLYVNAPEPPQV---LQELQPV 3202
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
V G +SG P P++ W + F G +++L + E FPED
Sbjct: 3203 TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3262
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAI 675
YTCEA N G T A L+V+ P D P + I+ + S GQ C +
Sbjct: 3263 YTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV 3322
Query: 676 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 735
+G + +D K K + F + Q ED + L + + P G Y + N VG+ S
Sbjct: 3323 SGTDLKVSWYSKDKK--IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVS 3380
Query: 736 CQVSLMLQNSS 746
+L L+ S
Sbjct: 3381 STANLSLEGFS 3391
Score = 92.4 bits (228), Expect = 3e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1221
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 18333 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18389
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 18390 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18449
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 18450 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18509
Query: 1341 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1369
YG EP + +T KP P EVS
Sbjct: 18510 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18539
Score = 92.4 bits (228), Expect = 3e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 23351 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23404
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 23405 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23464
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1325
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 23465 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23524
Query: 1326 LPDHEYKFRVRAINVYG 1342
+EY FRV A N +G
Sbjct: 23525 TEGNEYVFRVAATNRFG 23541
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 20912 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20971
Query: 1241 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 20972 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 21090
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1405
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 21091 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21134
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 16929 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16988
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 16989 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1232
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 9037 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 9096
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 9097 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9155
Query: 1293 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1349
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 9156 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9215
Query: 1350 SEL 1352
++
Sbjct: 9216 DKV 9218
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1157 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1213
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 10832 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10891
Query: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1273
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 10892 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10948
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1332
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 10949 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 11008
Query: 1333 FRVRAINVYG 1342
FRV A N YG
Sbjct: 11009 FRVAAENQYG 11018
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1163 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 15477 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15534
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 15535 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15593
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 15594 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15653
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A N YG P++ +E E+P P
Sbjct: 15654 LAENEYGIGLPAETAESVKASERPLPP 15680
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1180 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10220
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10279
Query: 1298 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 10280 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10339
Query: 1357 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1406
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 10340 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10391
Query: 1407 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1455
K T + + KE + +S +N + K C
Sbjct: 10392 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10433
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16639
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 16640 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16698
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 16699 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16758
Query: 1359 PEEP 1362
P+ P
Sbjct: 16759 PQPP 16762
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1159 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1209
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 23746 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23805
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 23806 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23863
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1328
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 23864 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23923
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1385
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 23924 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23983
Query: 1386 NTEQKVSDFY 1395
+ +V+ +Y
Sbjct: 23984 DGGSRVTGYY 23993
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 610
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 731 VGECSCQVSLMLQ 743
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.4 bits (220), Expect = 3e-17
Identities = 60/221 (27%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS 490
+K R + + ++E P F+ L + G++ ++ P P +TW +GQ I+ +
Sbjct: 25304 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 25363
Query: 491 ------TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 544
+ G+ +L I +D YT +A N G+ SC A +TV L
Sbjct: 25364 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV----------TLH 25413
Query: 545 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604
P P+F + L++ + +G V ++VSG PPP + W +G + +
Sbjct: 25414 PPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH 25473
Query: 605 RGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
G ++L I++ PEDTG Y A N+AG QA L V+
Sbjct: 25474 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514
Score = 87.8 bits (216), Expect = 9e-17
Identities = 144/684 (21%), Positives = 237/684 (34%), Gaps = 121/684 (17%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIH 221
F +++ + EG F CK++G P P++ W K ++ R + ++G L I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISK 281
V +D G+YT N G A S +L ++ T S +R +S+
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
+ A S SP R + + + ES+LE R VL+
Sbjct: 1367 SP--IRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLE------RLYKPVFVLKPV 1418
Query: 342 S-SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAAN 400
S + Q AR + K P P TF Q +V+ +
Sbjct: 1419 SFKCLEGQTARF-----------------DLKVVGRPMPETFWFHD----GQQIVNDYTH 1457
Query: 401 RRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEGLAVME-----VAPSFSSVLK 452
+ + E S + S E V +N+ + + +E V P F LK
Sbjct: 1458 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLK 1517
Query: 453 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPE 507
+ + EG ++ G P P I WL N P +Y + E G A L I + +
Sbjct: 1518 NVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQ 1577
Query: 508 DHGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP-------- 548
D YT A N G+ C V V + + + ++P AP
Sbjct: 1578 DSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLR 1637
Query: 549 --------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGN 592
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1638 YGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGK 1697
Query: 593 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE------- 645
++ + SL + D+G TC A N G T A L V++
Sbjct: 1698 PLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757
Query: 646 -------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCA 674
H+G +P + P V G++ C
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
+ G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1818 VTGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVI 1875
Query: 735 SCQVSLMLQNSS--ARALPRGREP 756
+V L +Q L R EP
Sbjct: 1876 EHKVKLEIQQREDFRSVLRRAPEP 1899
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1163 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1216
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 12225 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12281
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12340
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 12341 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12400
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A+N YG P+ + + EP
Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEP 12427
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 13303 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13362
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 13363 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13421
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1328
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 13422 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13481
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1359
Y FRV A N YG +P + + + P
Sbjct: 13482 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13512
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1168 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 18732 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18789
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 18790 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18848
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 18849 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Query: 1344 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P++ +E V E P P V +V T TI E+ SD
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18950
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 17664 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17721
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 17722 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17780
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 17781 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17840
Query: 1359 PEEP 1362
P P
Sbjct: 17841 PSPP 17844
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 18011 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 18070
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 18071 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18118
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 85.1 bits (209), Expect = 6e-16
Identities = 178/820 (21%), Positives = 302/820 (36%), Gaps = 113/820 (13%)
Query: 367 SGEERKRPAPP--RPATFPTRQPGLGSQDVVSKAANRR-IPMEGQRDSAFPKFESKPQSQ 423
SG+ PA P P PT +P + + ++ +R I M R S ++
Sbjct: 1330 SGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPA 1389
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
+ + ++ E P F +EGQ V G P+P W +GQ
Sbjct: 1390 RMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQ 1449
Query: 484 PI--QYARSTC--EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 539
I Y E G L I A P D G +T +A+N G+ S S +TV + K
Sbjct: 1450 QIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1509
Query: 540 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
P+F++ L ++ + +GS++ M V+ +GNP P+++WL N + I +
Sbjct: 1510 --------------PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1555
Query: 600 FHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 657
GT + +L I +D+ YT A N AG T+ + V+ +P
Sbjct: 1556 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEP----- 1610
Query: 658 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF------TLV 711
R + G + IA +H LR G+ ++ ++ + + F +L
Sbjct: 1611 ERKLIIPRG--TYRAKEIAAPELEPLH-LRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR 1667
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR---EPASCEDLCGGGVG 768
LK+ P H +E L +G+ + V + A R R E C G
Sbjct: 1668 LKRFGPAH---FECRL-TPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1723
Query: 769 ADGG-----GSDRYGSLRPGWP--ARGQGWLEEED--GEDVRGVLKRRVETRQHTEEAIR 819
D G +++YG+ + + L EE E +G+ + R E A+
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALT 1783
Query: 820 QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKT--------VSE 871
+Q + K+ L + ++ + E FR + +PK + +
Sbjct: 1784 GVTTDQKE------KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRK 1837
Query: 872 EER------KVHSPQQVDFRS--VLAKKGTSKTP---VPEKVPPPKPATPDFRSVLGGKK 920
+R +H VD +S K T++ P + KV DFRSVL
Sbjct: 1838 SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1897
Query: 921 KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 980
+ E L + + +P+ + K V K AE + + +E L+
Sbjct: 1898 EPRPEFHVHEPGKLQFEVQKVDRPVDTTE----TKEVVKLKRAERITHEKVPEESEELRS 1953
Query: 981 MGNAKPDE---------NLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQG 1026
+ +E LKS K+E +++ + H T+ EK++ E +
Sbjct: 1954 KFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKI 2013
Query: 1027 TAPAFK----------------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTL 1069
T P FK +++Q V +G + +V P W NG K
Sbjct: 2014 TIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE 2073
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
++ + E ++C + I ED A N AG+
Sbjct: 2074 RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2113
Score = 84.7 bits (208), Expect = 7e-16
Identities = 150/724 (20%), Positives = 239/724 (33%), Gaps = 89/724 (12%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438
T PT +P +I + ++ PK + QSQ V + FR
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVR-- 2054
Query: 439 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC----EA 494
V G P P W NG I+ + E
Sbjct: 2055 -----------------------------VVGKPDPECEWYKNGVKIERSDRIYWYWPED 2085
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
V EL I+D ED + A N G+ S A++ V K+
Sbjct: 2086 NVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ-----------------LI 2128
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F Q L D+ + + + P +V W +G E+ E + + H L I
Sbjct: 2129 TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSIL 2188
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ D Y+C V+T A L V +G F+ + + + S + C
Sbjct: 2189 TIDTSDAEDYSCVLVEDE-NVKTTAKLIV----EGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ + W + L K G + + L +K V G+Y ++ + C
Sbjct: 2244 VSPENIEG-KWYHNDVEL-KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2301
Query: 735 SCQV 738
++
Sbjct: 2302 KLKM 2305
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 13634 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 13694 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13753
Query: 1312 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
A+ + T+F V L EY FRV A N YG E
Sbjct: 13754 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13788
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1168 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 20101 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20160
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 20161 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20220
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 20221 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20280
Query: 1344 SE 1345
S+
Sbjct: 20281 SD 20282
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1169 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 21583 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21642
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 21643 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21702
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 21703 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21762
Query: 1344 SEP 1346
P
Sbjct: 21763 GRP 21765
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 813 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 869
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726
Query: 870 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 928
SE K + + S + K T V P+ A+P F K +P
Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783
Query: 929 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 986
A + K LS + + + + A T+KP AE L A
Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840
Query: 987 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1026
+ KS + E+KK+V + GTT E+R E
Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894
Query: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1086
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071
Query: 1205 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1017 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 6615 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6674
Query: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 6675 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6719
Query: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
PV E T + + ++ + G S ++ G V
Sbjct: 6720 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6756
Query: 1196 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1253
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 6757 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6816
Query: 1254 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 6817 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6869
Query: 1314 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 6870 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6929
Query: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1424
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 6930 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6989
Query: 1425 FFKAYSAKEKENIRQEISIMNCL 1447
+ SA+ K + I+ L
Sbjct: 6990 YLYRVSAENKAGVSDPSEILGPL 7012
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 19826 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19883
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 19884 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19942
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 19943 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 20002
Query: 1359 PEEPK 1363
P P+
Sbjct: 20003 PSPPE 20007
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 24535 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24594
Query: 593 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 650
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 24595 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24654
Query: 651 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 710
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 24655 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24713
Query: 711 VLKK-VQPWHAGQYEILLKNRVG 732
V V+ AG Y + KNR G
Sbjct: 24714 VFPNGVERKDAGFYVVCAKNRFG 24736
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 25307 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25366
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 25367 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25419
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 25420 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 25521 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25552
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1237
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11900
Query: 1238 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 11901 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11959
Query: 1298 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1354
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 11960 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 12019
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1395
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 12020 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12059
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24277
Query: 673 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 731
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 24278 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24336
Query: 732 GECSCQVSLMLQN 744
G + + +Q+
Sbjct: 24337 GTVDAILDVEIQD 24349
Score = 81.6 bits (200), Expect = 6e-15
Identities = 75/315 (23%), Positives = 116/315 (36%), Gaps = 74/315 (23%)
Query: 12 ISKTSLSVDPSRVD---SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
ISKT + + D S L++APAFI PR+ I EG F + G P P++ W +
Sbjct: 26738 ISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 26797
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL------- 121
N PI+ + R +SL I D GKYT +A N G T L
Sbjct: 26798 NNLPISISSNVSISRS-RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856
Query: 122 --------------TVEGSFAKQLGQPVVSKTLGD---------------RFSAPAVETR 152
+++GSF+ Q Q SK +F++ + ++
Sbjct: 26857 EPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSM 26916
Query: 153 PSIWGE--------------------------------CPPKFATKLGRVVVKEGQMGRF 180
S+ PPK + + EG++
Sbjct: 26917 SSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTV 26976
Query: 181 SCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
+C TG P P+VTW G + Q R + + + L I V + D G+YT + N
Sbjct: 26977 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 27036
Query: 239 SGKASMSAELSIQGL 253
G S + + I+ +
Sbjct: 27037 FGSDSATVNIHIRSI 27051
Score = 81.3 bits (199), Expect = 8e-15
Identities = 123/536 (22%), Positives = 192/536 (35%), Gaps = 142/536 (26%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 26646 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26696
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 26697 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26754
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 26755 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26784
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 26785 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26844
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 26845 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26887
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 26888 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26932
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 26933 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26964
Query: 422 SQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481
+ E + V+ VA C+ G P P +TW
Sbjct: 26965 DISIDEGK----------VLTVA---------------------CAFTGEPTPEVTWSCG 26993
Query: 482 GQPI---QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
G+ I + R E + L I D +D G YT N G S SA V +H
Sbjct: 26994 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG--SDSATVNIH 27047
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 22671 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22787
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 22788 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22847
Query: 1341 YG-----TSEPSQESELTTVGEKPEEPKD 1364
YG SEP T+ P P++
Sbjct: 22848 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22876
Score = 80.1 bits (196), Expect = 2e-14
Identities = 170/794 (21%), Positives = 285/794 (35%), Gaps = 143/794 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 5446 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5496
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 5497 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5555
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 5556 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5615
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 5616 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5675
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V W K ++PS + ++L + + D+G YTC G S +L I
Sbjct: 5676 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5730
Query: 251 QGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAA 310
+ +R + +V + T E D + A K K + Q
Sbjct: 5731 E-----DREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQ--------- 5776
Query: 311 NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEE 370
+ E K+ S QT + ++++ +A ++ +PR +G+L P +
Sbjct: 5777 TPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVK-SSAHLRVKPRV--IGLLRPLKDV 5833
Query: 371 RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
ATF L +D+ + + +E D P+ E K + +++
Sbjct: 5834 TVTAG--ETATFDCE---LSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRD--- 5884
Query: 431 VKFRCEG--------------LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 476
VK G L V E F+ L+D V EG VL+C V ++
Sbjct: 5885 VKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKV 5943
Query: 477 TWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
W NG I ++ + V +L I D PED TYTC A++ + SC+ V
Sbjct: 5944 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 5998
Query: 534 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
P FL+ L+DL+V + ++S +V W +G E
Sbjct: 5999 -----------------PPHVEFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAE 6040
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPW 653
I++ + + +G L I + +D Y+CE + RT +LTV E +
Sbjct: 6041 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLE----EEAV 6092
Query: 654 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 713
F ++ S ++ + C ++ P V W + + + +TG +E+L LV++
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEII-ETGRYEILTEGRKRILVIQ 6150
Query: 714 KVQPWHAGQYEILL 727
AG Y L
Sbjct: 6151 NAHLEDAGNYNCRL 6164
Score = 80.1 bits (196), Expect = 2e-14
Identities = 181/813 (22%), Positives = 280/813 (34%), Gaps = 141/813 (17%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 25998 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 26056
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 26057 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 26116
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 26117 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26175
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 26176 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26235
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 26236 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26288
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 26289 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26339
Query: 328 SPRTAPQ--TPVLQ-KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAP-----PRP 379
P +AP T L+ + S I V+ G++ K
Sbjct: 26340 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26399
Query: 380 ATFPTRQPGLGSQDV---------VSKAANRRIPMEGQRDSAFPKFESK----PQSQEVK 426
T+ + L D + + GQ + + SK +S +
Sbjct: 26400 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26459
Query: 427 ENQTVKFRCEGLAVMEVA--PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRIT--WLLNG 482
TV + E A ++ P + L+D V D V + +V+ T PR T W +G
Sbjct: 26460 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTV--SSDSVAKFAVKATGEPRPTAIWTKDG 26517
Query: 483 QPI----QYARSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 537
+ I +Y S + G E+H D D G YTC +N+ G VS S +T+ K +
Sbjct: 26518 KAITQGGKYKLSEDKGGFFLEIHKTDT--SDSGLYTCTVKNSAGSVSSSCKLTIKAIKDT 26575
Query: 538 RKSEY-LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
+ + P +Q K + ++ M+ ++ +++
Sbjct: 26576 EAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS---EAKSQEKLALKEEASKVLI 26632
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
SE+ ++ SL V E T T ++ EVRT A + S
Sbjct: 26633 SEEV---KKSAATSLEKSIVHEEITKTS-----QASEEVRTHAEIKA-----------FS 26673
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
S+ GQ +++ IAG V W+ +G L + + D TL +K+
Sbjct: 26674 TQMSINE--GQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQ-TLTIKQAS 26728
Query: 717 PWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 749
G + K + G CQ L L + A
Sbjct: 26729 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDA 26761
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 14706 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14765
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 14766 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14825
Query: 1301 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1342
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 14826 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14868
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1669 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1728
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 1729 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 79.0 bits (193), Expect = 4e-14
Identities = 148/719 (20%), Positives = 276/719 (38%), Gaps = 111/719 (15%)
Query: 35 FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVI 93
F+ P +L ++E A+FE + +V W ++G I G ++ D +G LVI
Sbjct: 6004 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVI 6060
Query: 94 HAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRP 153
+ +D +Y+CE + +TV L E F K L VS+T
Sbjct: 6061 NKCLLDDEAEYSCEVRTARTSGMLTV-LEEEAVFTKNLANIEVSET-------------- 6105
Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
+ C+++ +P +V W KG+ + + R + +
Sbjct: 6106 ----------------------DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEG 6142
Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNG--SGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
++L I + +D G Y C + + GK + EL+ + + + E +
Sbjct: 6143 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAEFISKPQNLEILEGE------ 6195
Query: 272 RKEVTNVISKES-----KLD--SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324
+ E ISKES K D +LE+ K + ++ A Q + +
Sbjct: 6196 KAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGA 6255
Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384
R A V++K + L+ RV+ + ++ G + K A F +
Sbjct: 6256 A----RAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKW-FRNEEAIFDS 6310
Query: 385 RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVA 444
+ + +D+V R ++ Q + + + + + VK + E L ++E
Sbjct: 6311 SKYIILQKDLVYTLRIRDAHLDDQAN--YNVSLTNHRGENVKSAANLIVEEEDLRIVEP- 6367
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---I 501
LKD +E + C V V + W NG+ + + H I
Sbjct: 6368 ------LKDIETMEKKSVTFWCKVNRLNVT-LKWTKNGEEVPFDNRVSYRVDKYKHMLTI 6420
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+D D G Y VT + KS +E L+ AP++ F++ L
Sbjct: 6421 KDCGFPDEGEYI---------------VTAGQDKSV--AELLIIEAPTE-----FVEHLE 6458
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D V + + Q+S V W NG EI+E + + FE+ G+ H L I++ +D
Sbjct: 6459 DQTVTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDE 6517
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE-PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Y C + +++A L V+E P + +P P+ + + G V+ + D
Sbjct: 6518 CEYAC----GVEDRKSRARLFVEEIPVEIIRP-----PQDILEAPGADVVFLAELNKDKV 6568
Query: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
V WLR+ + + H +++ + L + ++P G+Y + K++ +++
Sbjct: 6569 -EVQWLRNNMVVVQGDKH-QMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELA 6625
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1156 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1207
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 8292 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8349
Query: 1208 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1241
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 8350 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8409
Query: 1242 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1301
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 8410 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8468
Query: 1302 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 8469 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8526
Query: 1359 PEEPKD 1364
P P D
Sbjct: 8527 PFGPPD 8532
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1159 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 7011 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 7070
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 7071 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7129
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1335
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 7130 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7189
Query: 1336 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1364
A N G EP+ E ++T P+ P++
Sbjct: 7190 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7221
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 22174 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22233
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22265
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+K+ T + Q+I +AG + ++G TW +
Sbjct: 22266 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22315
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1268
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 22316 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22375
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1327
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 22376 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
EY FRV + N +G S+P + + + + E P P
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22468
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 16858 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16917
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y N GQ S ++ D P + K P
Sbjct: 16918 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16960
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
D + + PP QI + ++ T W
Sbjct: 16961 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 17004
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1263
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 17005 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 17052
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1316
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 17053 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 17106
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 17107 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17152
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 6453 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6511
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1137
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 6512 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6571
Query: 1138 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1172
++++ V G + + K + + A P+I
Sbjct: 6572 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6631
Query: 1173 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1232
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 6632 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6688
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 6689 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6747
Query: 1293 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1349
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 6748 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6806
Query: 1350 SELTTVGEKPEEPKDEVEVSDDD 1372
K + P + V+ D
Sbjct: 6807 DNPVEARSKYDVPGPPLNVTITD 6829
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1652 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1710
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 1771 ATCTAELIVETMEEGEGE 1788
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
K P+ L D +G V +T ++ EV W + E F Q +
Sbjct: 4364 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4421
Query: 610 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 668
+L I +V ED G Y CEA N +G+ T A LTV + P K + +LG
Sbjct: 4422 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4478
Query: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 728
+C I P W + G+ + ++ + ++ + +L + + Q G+Y
Sbjct: 4479 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4537
Query: 729 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 784
N G SC +L + R L R+P E++ S+
Sbjct: 4538 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4584
Query: 785 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 844
P + +E + E V K+ + + + EV + R+ +K+ T +
Sbjct: 4585 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4637
Query: 845 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 901
IP + + + +V KP V E + +P V V+ KK +K P E
Sbjct: 4638 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4694
Query: 902 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 958
P P + G KK P+ + + E P + + PLK V
Sbjct: 4695 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4747
Query: 959 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1004
K + +G++ E L A K N++ + K D K+
Sbjct: 4748 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4807
Query: 1005 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1055
+ C + G+ T K + K ++V V +G+ L L C+++ +
Sbjct: 4808 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4867
Query: 1056 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1114
++W +GK ++ I+ G + +++I A D G Y +N A ECS
Sbjct: 4868 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4924
Query: 1115 QVTV 1118
V V
Sbjct: 4925 CVKV 4928
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 983 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1036
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 7963 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 8022
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 8023 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 8082
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1156
G+Y +N G A S V V P ++K+ SD T
Sbjct: 8083 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 8124
Query: 1157 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PP+ G PI ++ R++ ++
Sbjct: 8125 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8156
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1274
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 8157 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8216
Query: 1275 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1326
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 8217 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8273
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1373
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 8274 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8324
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1155
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 20174 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20219
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 20220 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20269
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1275
+EN + + + S V L P PP+ TP +++
Sbjct: 20270 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20310
Query: 1276 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1333
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 20311 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20370
Query: 1334 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 20371 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20429
Query: 1394 FYDIEER 1400
Y +E R
Sbjct: 20430 -YIVERR 20435
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLV 3790
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1259
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 23895 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23954
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1317
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 23955 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 24014
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1368
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 24015 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 24067
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 8726 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8781
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1278
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 8782 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8841
Query: 1279 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1338
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 8842 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8900
Query: 1339 NVYGTSEPSQESELTTV 1355
N +G P + + V
Sbjct: 8901 NKFGCGPPVEIGPILAV 8917
Score = 71.6 bits (174), Expect = 6e-12
Identities = 46/152 (30%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Query: 1631 AVRAIGRLSSMAMIS--GLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK 1688
A A+G++SS A +S G S + +T + ++ +E + Q K
Sbjct: 3372 ASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQ-------------K 3418
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED-GNCSL 1747
P F + + L V G RF ++ G P PE+ WF + Q I ++ ++E G +
Sbjct: 3419 PSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALM 3478
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+I D + +Y+CKA NS GEATC A L V
Sbjct: 3479 LIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510
Score = 71.6 bits (174), Expect = 6e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 20792 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20850
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 20851 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20904
Score = 71.2 bits (173), Expect = 8e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1255
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 7552 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7600
Query: 1256 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 7601 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7660
Query: 1312 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1368
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 7661 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7720
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
SE +GT P F +++ + ++ G L V P I W NG L + +G
Sbjct: 3575 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3634
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
S+ I ED G Y C+A ND G+ CS + + N+K K
Sbjct: 3635 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3680
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
TE+++ V K P PP ++ + + G V G T T
Sbjct: 3681 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3732
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+
Sbjct: 3733 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3792
Query: 1261 KPDPPAGTPC 1270
+ TPC
Sbjct: 3793 EDTDMTDTPC 3802
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21260
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y + N C++ V P + T P K + P
Sbjct: 21261 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21291
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1214
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 21292 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21333
Query: 1215 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1268
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 21334 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21390
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1326
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 21391 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21450
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1386
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 21451 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21502
Query: 1387 TEQKVSD------FYDIEERLGSGKF 1406
+ D Y IE+R G+ ++
Sbjct: 21503 WNPPLRDGGSKIVGYSIEKRQGNERW 21528
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 7325 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7384
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y A N G+A +V V D P PP +D T +
Sbjct: 7385 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7426
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
PP+ +I + +++ E W K ++++
Sbjct: 7427 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7470
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1270
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 7471 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7517
Query: 1271 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1327
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 7518 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7577
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 7578 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7612
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1746
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 70.1 bits (170), Expect = 2e-11
Identities = 59/236 (25%), Positives = 92/236 (38%), Gaps = 24/236 (10%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA LQD +EG+ QC+VS + W K +K ++F ++Q + I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDD-APASENTKAPEMKSRRPKSSLPPVLGT 1147
+A PED G Y VA N GQ + ++++ + ENT +
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWH-------------V 3404
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
+ KK+P P IQ +V GE+V +V+G W ++
Sbjct: 3405 SLSVSFKKEP-------LGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQ 3457
Query: 1208 QIQESEHM--KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
I ++ + E S + + I+ A EH G Y+ N G LTV K
Sbjct: 3458 LILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPK 3513
Score = 69.3 bits (168), Expect = 3e-11
Identities = 153/729 (20%), Positives = 270/729 (37%), Gaps = 101/729 (13%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 497
L V E+ F+ LKD V E + +C + T + W I+ +
Sbjct: 5107 LTVKEIELDFAVPLKDVTVPERRQARFECVL--TREANVIWSKGPDIIKSSDKFDIIADG 5164
Query: 498 ELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
+ HI D+ +D G YT E + S +VT K
Sbjct: 5165 KKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGIRLK------------------- 5203
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F+ L D V +G T ++S + V+W N ++ S G H L ++
Sbjct: 5204 -FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMK 5261
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
EV +D + E+ + A L V E P+F K TA + + C
Sbjct: 5262 EVTLDDISQIKAQV----KELSSTAQLKVLE----ADPYFTVKLHDKTAVEKDEITLKCE 5313
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ D V W +DG+ + + + + L +KK G+Y C
Sbjct: 5314 VSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYV---------C 5361
Query: 735 SCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG---ADGGGSDRYGSLRPGWPARGQG 790
C N + A L + +P ++ G + D +G W +GQ
Sbjct: 5362 DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ----WKLKGQP 5417
Query: 791 WLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLS 842
D E + K + T + + +A + L ++L + LS
Sbjct: 5418 LTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKEL--PLIFITPLS 5475
Query: 843 EDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQV--DFRSVLAKKGTSKTPVPE 900
D+K ++ F + R+ PKT R + Q++ D R L K GT + V +
Sbjct: 5476 --DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQEITGDDRFELIKDGTKHSMVIK 5527
Query: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
A F + + +G E + K + K ++ + + V +
Sbjct: 5528 SAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS 5581
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
+K N + T + + + + + S + ++L D + + + G + K
Sbjct: 5582 HDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDLSIDDTSQIRVEA--MGMSSEAK 5638
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
+ +G P F KLQD E +++LQC++S A + W +GK +K +K ++ +
Sbjct: 5639 LTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVIKAD 5696
Query: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
G + ++KAL D G Y C D G + S ++ ++D E+K RP S
Sbjct: 5697 GKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR---------EIKLVRPLHS 5743
Query: 1141 LPPVLGTES 1149
+ V+ TE+
Sbjct: 5744 V-EVMETET 5751
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1148 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1202
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 17038 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 17097
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
K K I K +N E G + + + EN +G +A N
Sbjct: 17098 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17146
Query: 1263 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1318
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 17147 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17206
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1369
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 17207 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17266
Query: 1370 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1426
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 17267 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17326
Query: 1427 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1485
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 17327 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17386
Query: 1486 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1529
E + E + +++ EG EY+ + IM VNK G
Sbjct: 17387 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17428
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1288
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 19678 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19737
Query: 1289 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 19738 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19797
Query: 1348 QESELTTVGEKPEEPKDEVE 1367
S+ E+ EEP +++
Sbjct: 19798 DSSDPQIAKEREEEPLFDID 19817
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 11829 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11888
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1144
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 11889 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11940
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
TV P P+ + I++ E +++ W
Sbjct: 11941 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11973
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1261
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 11974 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 12021
Query: 1262 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 12022 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 12077
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 12078 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 12124
Score = 68.6 bits (166), Expect = 5e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 19082
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++A ED G Y+ N AG + V D P PP
Sbjct: 19083 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 19124
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+ + PP+ QI + ++K + + TW +
Sbjct: 19125 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19168
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1264
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 19169 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19216
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1317
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 19217 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19271
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1377
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 19272 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19330
Query: 1378 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1406
+ + + K++ + L G++
Sbjct: 19331 LKWSKPHYDGGAKITGYIVERRELPDGRW 19359
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 26755 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26814
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1125
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 26815 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26874
Query: 1126 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1166
++++ +M + + ++S + + + + K A + +
Sbjct: 26875 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26934
Query: 1167 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
+PP+I P D + G+ + + TG TW
Sbjct: 26935 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26994
Query: 1207 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 26995 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 67.8 bits (164), Expect = 9e-11
Identities = 72/265 (27%), Positives = 99/265 (37%), Gaps = 26/265 (9%)
Query: 389 LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE--VKENQTVKFR-CEGLAVMEVAP 445
L + V A+ + E Q +S P E + S E +E TVK + EG + E P
Sbjct: 4309 LDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGP 4368
Query: 446 SFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQ 502
+ L D EG L S+ T + W + + + + + L I
Sbjct: 4369 MIHTPLVDTVSEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVID 4426
Query: 503 DALPEDH-GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
EDH G Y C A N G+ + SA +TV K AP+ + +
Sbjct: 4427 KVNTEDHQGEYVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIE 4469
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
L+V G T ++ P W G EI ES+ SL I D
Sbjct: 4470 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 4529
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEP 646
G YTC+A N G V A LTV P
Sbjct: 4530 GEYTCKASNEYGSVSCTATLTVTVP 4554
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1668 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1085
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP II +D G+ +V+GT + +W
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
K+I+ S ++ E+ +L I A E G YT + N +G + NL++
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 11145 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11204
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11252
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P P I E Q R + +G V+
Sbjct: 11253 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11283
Query: 1215 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1267
+GS T L GC + + ENK+G + V K P P G
Sbjct: 11284 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11336
Query: 1268 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1321
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 11337 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11391
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
V L + Y+FRV A N+ G S+PS S+
Sbjct: 11392 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11421
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 12935 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12994
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1155
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 12995 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 13054
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
K P A +V+ T PIT ++ K I+ E+
Sbjct: 13055 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 13087
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1271
+ + ENK G + K DPP P
Sbjct: 13088 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 13124
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 13125 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13184
Query: 1330 EYKFRVRAINVYGTSEPSQESE 1351
EY+FRV AIN G +PS S+
Sbjct: 13185 EYEFRVTAINKAGPGKPSDASK 13206
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1014 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1065
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 19792 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19851
Query: 1066 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 19852 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19907
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1185
PP T D T + A + + PE+
Sbjct: 19908 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19932
Query: 1186 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1243
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 19933 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19981
Query: 1244 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 19982 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 20040
Query: 1301 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1360
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 20041 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 20100
Query: 1361 EPKDEVE 1367
P+ +++
Sbjct: 20101 PPEIDMK 20107
Score = 65.9 bits (159), Expect = 3e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8800
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y A N G + +V V D P P L PV+ T +
Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8846
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 8847 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8882
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1273
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 8883 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8933
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1331
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 8934 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8993
Query: 1332 KFRVRAINVYGTSEPS 1347
+FRV+A+N G SEPS
Sbjct: 8994 EFRVKAVNEIGESEPS 9009
Score = 65.9 bits (159), Expect = 3e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15163
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A N G A+ V V D P P V S+ V P
Sbjct: 15164 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15210
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I+Q E ++ W ++Q ++
Sbjct: 15211 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15241
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1277
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 15242 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15297
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 15298 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15357
Query: 1336 RAINVYGTSEPSQES 1350
A N G S PS S
Sbjct: 15358 MAENAAGISAPSPTS 15372
Score = 65.9 bits (159), Expect = 3e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 15644 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15702
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 15703 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15762
Query: 1349 ES 1350
S
Sbjct: 15763 LS 15764
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 22970 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 23028
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 23029 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 23082
Score = 65.5 bits (158), Expect = 5e-10
Identities = 84/382 (21%), Positives = 154/382 (40%), Gaps = 28/382 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 17662 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17719
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 17720 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17771
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDSPRTAPQTPVLQKTSSSI--- 345
AK KN +R + AN + + S K+E+ + + + +
Sbjct: 17772 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17830
Query: 346 TLQAARVQPEPRAPGLGVLSPSG--------EERKRPAPPRPATFPTRQPGLGSQ--DVV 395
T+ A + P PG L+ E+ + R + G++ +V
Sbjct: 17831 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17890
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
+++ + G +F K +++ K + V + + PS +
Sbjct: 17891 AESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS 17950
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALPEDHGTY 512
+ G+D ++ V G P P I+W+ +G+P+ Q R E A LHI++ +D G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010
Query: 513 TCLAENALGQVSCSAWVTVHEK 534
T A N+ G + + V V EK
Sbjct: 18011 TVTATNSAGTATENLSVIVLEK 18032
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 24554 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24613
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 24614 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24655
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 24656 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24704
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 24705 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24758
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 24759 SDVSRDSVNLTWTEPASD 24776
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 17940 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17999
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y A N AG A + V V + P PPV
Sbjct: 18000 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 18041
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D + PP QI + +++ T TW
Sbjct: 18042 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 18085
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1262
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 18086 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18133
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1320
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 18134 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18192
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 18193 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18234
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 26166 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26224
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 26225 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26282
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 26283 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26342
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 26343 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26400
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 26401 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26460
Query: 275 VTNVISK 281
+ V K
Sbjct: 26461 ESTVTRK 26467
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 11548 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11607
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 11608 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11666
Query: 1300 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1356
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 11667 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11725
Query: 1357 -EKPEEPKD 1364
++P EP++
Sbjct: 11726 IDRPGEPEN 11734
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1146 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1200
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 13789 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13837
Query: 1201 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++F R + K K+T L E+ + ++ N G + +
Sbjct: 13838 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13895
Query: 1259 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 13896 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13955
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1362
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 13956 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 16726 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16784
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 16785 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16842
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1202
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 15957 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 16015
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+K K K E G + + + G +G V P
Sbjct: 16016 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 16066
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1320
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 16067 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16126
Query: 1321 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1363
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 16127 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16170
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20574
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G A + +V + D P P + T T+ +P P
Sbjct: 20575 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20621
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I++ E +V W SEH++ E
Sbjct: 20622 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20651
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 20652 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20708
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1335
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 20709 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768
Query: 1336 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1370
A+N G S+ SE + P P ++ ++D
Sbjct: 20769 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20805
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1314
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 9332 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9391
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 9392 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9446
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1314
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 10738 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10796
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1363
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 10797 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10845
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 994
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 12416 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12466
Query: 995 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1035
+EE D + + + + G + +K E++G A +Q L
Sbjct: 12467 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12526
Query: 1036 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12586
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1146
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 12587 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12631
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
++DA P + + I+ E V G+ V VT T +
Sbjct: 12632 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12682
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
K I E++ +EN G L K+ AQ V +P
Sbjct: 12683 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12727
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1319
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 12728 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12778
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 12779 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12828
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25266
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 25267 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25320
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 25321 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25380
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 25381 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1017 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1074
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1134
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760
Query: 1135 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1194
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1195 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1254
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 1255 NLTVVDKPD 1263
L + + D
Sbjct: 1880 KLEIQQRED 1888
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1317
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 16465 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16523
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 16524 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16574
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 500
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 24160 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24219
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 559
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 24220 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24266
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 24267 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24322
Query: 620 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 24323 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24371
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1260
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 9884 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1314
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 9944 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 10002
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 10003 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 10050
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11649
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
+ P D G IT +++RK Q+ +
Sbjct: 11650 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11680
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1271
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 11681 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11738
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 11739 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11797
Query: 1330 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 11798 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11836
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1074
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1125
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1169
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1170 QI 1171
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1239 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1295
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 14959 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 15017
Query: 1296 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1352
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 15018 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 15077
Query: 1353 TTVGEKPEEPKDEVEVSDDD 1372
T + E PK +V+V D
Sbjct: 15078 ITCRDDVEAPKIKVDVKFKD 15097
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15835
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 15836 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15877
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D T PP K G S+ + V T TW
Sbjct: 15878 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15919
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1262
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 15920 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15966
Query: 1263 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1318
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 15967 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 16026
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 16027 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 16085
Query: 1379 DYRTVTINTEQKVSDFYDIEERLGSGKF 1406
++ T + K++ + ++ L G++
Sbjct: 16086 QWKKPTYDGGSKITGYIVEKKELPEGRW 16113
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 16175 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16231
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16274
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1206
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 16275 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16324
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1261
KV G++ T + ++ NK G + + VV K
Sbjct: 16325 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16364
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1319
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 16365 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16423
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 16424 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16454
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W+K K + K + G + + + G +G V
Sbjct: 18179 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18229
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1319
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 18230 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18289
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 18290 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18338
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 21773 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21828
Query: 1312 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1366
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 21829 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21888
Query: 1367 EVSDDDEKEPEVDY 1380
+V+D + +++
Sbjct: 21889 KVTDTSKTTVSLEW 21902
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 18630 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18686
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 18687 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18738
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 23376 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23435
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1154
Y KN G + +V + D P P+ E DAT +
Sbjct: 23436 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23480
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 23481 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23530
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 23531 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23571
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1327
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 23572 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23626
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1363
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 23627 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23668
Score = 60.5 bits (145), Expect = 1e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 13217 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13275
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 13276 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13304
Score = 60.5 bits (145), Expect = 1e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1256 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 22168 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22226
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22273
Score = 60.5 bits (145), Expect = 1e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 26475 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26533
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 26534 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26570
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1315
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 15381 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15439
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 15440 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15471
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W K K + MKV + G Y + EN G + + V
Sbjct: 19261 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19309
Query: 1262 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1317
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19369
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 19370 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19425
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/318 (23%), Positives = 124/318 (38%), Gaps = 51/318 (16%)
Query: 430 TVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 489
T K EG V F L+D V E L+C V + W N ++
Sbjct: 2211 TAKLIVEGAVV-----EFVKELQDIEVPESYSGELECIVSPENIEG-KWYHNDVELKSNG 2264
Query: 490 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 546
T G L ++D ED G Y+ + + KK++ K +
Sbjct: 2265 KYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---------------KKTTCKLKM---- 2305
Query: 547 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG 606
KP LQGLSD KV +G V + V+VS E +W+ +G E+Q S+ H
Sbjct: 2306 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV-EGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 607 TQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
H L I+++ ED G Y+ +++G V +V I+ + V
Sbjct: 2362 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV------------ITPLKDVN 2409
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
G ++ C ++ +V W + + + K + + LV+ + G
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGP 2468
Query: 723 YEILLKNRVGECSCQVSL 740
Y++++ RV E +C +S+
Sbjct: 2469 YKLIV-GRV-ETNCNLSV 2484
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3576 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3635
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3636 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3684
Score = 58.9 bits (141), Expect = 4e-08
Identities = 34/105 (32%), Positives = 55/105 (52%), Gaps = 2/105 (1%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
D L I++ +D+ YT A N++G+ + TA L +E + E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFE 3394
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1062 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 7758 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7801
Query: 1121 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1180
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 7802 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7852
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
R G W+K K + +V + G+++ + G
Sbjct: 7853 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7893
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 7894 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7947
Query: 1298 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 7948 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 8007
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1387
+ +P ++E D E E V +R V + T
Sbjct: 8008 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 8045
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 17265 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17324
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
A N AG V V D P P V G S+ K
Sbjct: 17325 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17367
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1219
+PP I + +++ E+ L V ++ +T
Sbjct: 17368 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17403
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1274
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 17404 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17458
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1332
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 17459 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17518
Query: 1333 FRVRAINVYGTSEPS 1347
FRV A N G EPS
Sbjct: 17519 FRVSAENAAGVGEPS 17533
Score = 58.5 bits (140), Expect = 6e-08
Identities = 63/295 (21%), Positives = 120/295 (40%), Gaps = 37/295 (12%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEA 494
L V+E P F+ L+D +E + +LQC + P + W +G+ I+ +++ +
Sbjct: 5639 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADG 5697
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
L ++ AL D G YTC G S + + +++
Sbjct: 5698 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDREIK----------------- 5736
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
++ L ++VM+ ++S + W G + ++ D ++ G HSL +
Sbjct: 5737 -LVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIKEEGKIHSLVLH 5794
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ TG +A N V++ A L V+ G + + VT + G++ C
Sbjct: 5795 NCRLDQTGGVDFQAAN----VKSSAHLRVKPRVIG----LLRPLKDVTVTAGETATFDCE 5846
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
++ + P V W GK L + + V TL L+ V+ AG+ ++ K+
Sbjct: 5847 LSYEDIP-VEWYLKGKKL-EPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5899
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1021 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1078
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 18327 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18386
Query: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138
++ ++ + D G Y N G V V D P P
Sbjct: 18387 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18433
Query: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1198
V G ++ P A + II+ E ++
Sbjct: 18434 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18475
Query: 1199 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 18476 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18521
Query: 1259 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1312
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 18522 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18581
Query: 1313 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
T V L H Y+FRV A N G EPS+ S
Sbjct: 18582 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18619
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 24159 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24217
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 24218 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24268
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 24269 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24306
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 24307 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24366
Query: 269 SDV 271
S V
Sbjct: 24367 SAV 24369
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1317
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 24451 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24509
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 24510 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24560
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1087
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1145
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25542
Query: 1146 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1181
GTES +A V KPA T K +I + E++K+R
Sbjct: 25543 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25597
Score = 57.8 bits (138), Expect = 9e-08
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1747
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 9e-08
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 17815 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17874
Query: 1297 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 17875 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17924
Score = 57.8 bits (138), Expect = 9e-08
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1670 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25401 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25460
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25461 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25520
Query: 1787 GEGEEEEE 1794
E + +EE
Sbjct: 25521 QEFKSKEE 25528
Score = 57.4 bits (137), Expect = 1e-07
Identities = 65/290 (22%), Positives = 112/290 (38%), Gaps = 42/290 (14%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAEL 499
A LK+ V E QD V + V + W+ NG ++ YA S + + L
Sbjct: 2660 AVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV-KGTIYSL 2718
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ D Y LG++ SA + V K +K +
Sbjct: 2719 RIKNCAIVDESVYGF----RLGRLGASARLHVETVKIIKKPK------------------ 2756
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
D+ ++ + V V VS + P V W H EI+ S+ H L +Q + P
Sbjct: 2757 --DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPS 2813
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679
D G YT G++ +A L V+ H I P + TAS C ++
Sbjct: 2814 DAGEYTA----VVGQLECKAKLFVETLHITKTMKNIEVPETKTAS------FECEVSHFN 2863
Query: 680 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
P++ WL++G + + + F+++ + L++ + +Y + N
Sbjct: 2864 VPSM-WLKNGVEI-EMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2911
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1747
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 57.4 bits (137), Expect = 1e-07
Identities = 96/428 (22%), Positives = 149/428 (34%), Gaps = 56/428 (13%)
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
+ E G P+F Q L + V G+ + +VS P I W N + + TK ++ E
Sbjct: 3411 KKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFE 3470
Query: 1081 GS--LCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV-DDAPAS------ENTKAPE 1131
S + + I A E G Y C A N AG+A C+ +TV AP S E E
Sbjct: 3471 ESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTVTPKAPESILHERIEQEIEME 3530
Query: 1132 MK----------------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFP 1175
MK + S + L S++ V P K P I+
Sbjct: 3531 MKEFSSSFLSAEEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEV 3588
Query: 1176 EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEH 1235
+ + G+ L V G W + S K + L IL + E
Sbjct: 3589 SNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLED 3648
Query: 1236 CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY------- 1288
G YT + N G L + K + T S + S L +
Sbjct: 3649 EGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKP 3708
Query: 1289 ----DGGSAVQSYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHE 1330
G A+ Y++ + TW K+L T S +F V D +
Sbjct: 3709 IRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDS 3768
Query: 1331 YKFRVRAINVYGTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1386
+ +A N+ G S + E E T + + P + K E +D + P ++
Sbjct: 3769 GLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALD 3828
Query: 1387 TEQKVSDF 1394
+EQ+++ F
Sbjct: 3829 SEQEIATF 3836
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 17545 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17603
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1373
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17657
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1233 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1289
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 18891 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18950
Query: 1290 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 18951 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)
Query: 852 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 909
E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V +
Sbjct: 4267 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325
Query: 910 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 964
S+ ++K + + S + E K E+ L + GP+ P+ + E
Sbjct: 4326 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4383
Query: 965 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1014
+ NAK DE K + V + VN + H G
Sbjct: 4384 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4442
Query: 1015 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1069
T + K + + AP K+K++ + VA G C++ S P W G+ +
Sbjct: 4443 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4502
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1129
+ + + S+ I + D G Y C A N+ G C+ +TV P E
Sbjct: 4503 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4561
Query: 1130 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+ R+P+ VL + ++K+P PK PK + PE + E V
Sbjct: 4562 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4617
Query: 1187 EL 1188
E+
Sbjct: 4618 EV 4619
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 10164 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10221
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
+AKN+AG+ + + V V D P T P + S
Sbjct: 10222 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10261
Query: 1160 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
++ F PED G PIT ++ +++ V
Sbjct: 10262 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10295
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1272
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 10296 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10354
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1330
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 10355 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10414
Query: 1331 YKFRVRAINVYGTSEPS 1347
Y++RV A+N+ G +PS
Sbjct: 10415 YEYRVSAVNIVGQGKPS 10431
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A+N G+ + V D P PP + D
Sbjct: 14768 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14798
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
+ + F D G V Q + TW++ + + +
Sbjct: 14799 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14847
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 14848 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14901
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 14902 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14961
Query: 1336 RAINVYGTSEPSQESE 1351
A N+ G S+PS+ SE
Sbjct: 14962 IAENMAGKSKPSKPSE 14977
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 988 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1046
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 22234 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22293
Query: 1047 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1106
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 22294 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22353
Query: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
AG S V V P P + V +++ V PK
Sbjct: 22354 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22400
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+ I++ E T W ++ ++ K+
Sbjct: 22401 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22430
Query: 1227 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1282
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 22431 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22488
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 22489 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22548
Query: 1341 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
G S+ S+ S + + P + EV+D
Sbjct: 22549 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22577
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1318
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 14300 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14359
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 14360 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14410
Query: 1379 DYRTVTINTEQKVSDFYDIEER 1400
RT+ + + F I+ R
Sbjct: 14411 -RRTLVVRAGLSIRIFVPIKGR 14431
Score = 56.2 bits (134), Expect = 3e-07
Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELH 500
P F +L + EGQ + V G P P + W +GQP+ + G+ LH
Sbjct: 25423 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25482
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY 542
I+D LPED G Y A N G SC A + V E+ +K E+
Sbjct: 25483 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-ERLRYKKQEF 25523
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1657 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1714
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1715 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 1775 AELIVETMEE 1784
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 14562 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14620
Query: 1291 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 14621 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14679
Query: 1351 ELTTVGEKPEEPK 1363
V E+ P+
Sbjct: 14680 RPVIVKEQTMLPE 14692
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1266 A 1266
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1743
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24552 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24611
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
LII+ V DD Y +A N G + TA L VE
Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26820
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26821 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26856
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1319
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 10050 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 10107
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 10108 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10160
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1317
KP P P D + L W DGGS + Y +E W + R
Sbjct: 11430 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11489
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 11490 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1199
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 12010 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 12067
Query: 1200 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
W+ K MKV+N +H + + EN++G + + V
Sbjct: 12068 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 12116
Query: 1260 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1309
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 12117 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12176
Query: 1310 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 12177 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236
Query: 1367 EVS 1369
+ S
Sbjct: 12237 DAS 12239
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1330
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 23273 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23332
Query: 1331 YKFRVRAINVYGTSEPSQESELTTV 1355
Y FR+RA N G SEP + TV
Sbjct: 23333 YLFRIRAQNEKGVSEPRETVTAVTV 23357
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 498
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 24555 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24614
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 24615 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24660
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 24661 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24716
Query: 619 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 665
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 24717 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24776
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA 691
G S + + + WLR G+A
Sbjct: 24777 GGSKITNYIVEKCATTAERWLRVGQA 24802
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1314
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 9640 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9698
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1362
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 9699 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9745
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1239 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 21457 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21516
Query: 1297 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1350
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 21517 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572
Query: 1351 ELTTVGEKPEEP 1362
+ ++ P
Sbjct: 21573 GIIMTRDENVPP 21584
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1677 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 1737 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1089
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 10452 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10507
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
KA D G Y V +N G + CQV V D P PPV
Sbjct: 10508 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10549
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
D K P I +K G+ V + + + TC K K +
Sbjct: 10550 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10605
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 10606 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10650
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1326
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 10651 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10705
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1379
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 10706 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10758
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 15761 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15803
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 15804 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16928
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 16929 GITVANVVGQKTASIEI 16945
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1745
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25376
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25377 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 1667 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4444 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4499
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4500 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4557
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26469 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26528
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1788
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26529 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26578
Score = 53.5 bits (127), Expect = 2e-06
Identities = 66/288 (22%), Positives = 114/288 (39%), Gaps = 41/288 (14%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDA 504
+ +K+ V E + +C V VP + WL NG I+ + + + +L I +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNT 2897
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG-LSDL 563
ED YT + N QVS + VT PI + L D+
Sbjct: 2898 STEDSAEYTFVCGN--DQVSATLTVT-----------------------PIMITSMLKDI 2932
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
+ +T V V+ WL NG EI+ ++ + HSL I+ V D
Sbjct: 2933 NAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAAD 2991
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
YT AG+ + A L V+ H F + + + + C ++ +P TV
Sbjct: 2992 YTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLEKKRAMFECEVS-EPDITV 3042
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 731
W++D + L + T ++ + + V L++ + AG+Y ++ V
Sbjct: 3043 QWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3089
Score = 53.1 bits (126), Expect = 2e-06
Identities = 95/436 (21%), Positives = 157/436 (36%), Gaps = 67/436 (15%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16639
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
T + N SG + SA ++++ LD+ + N V + + +S + L+
Sbjct: 16640 TLTLENSSG--TKSAFVTVRVLDT-------PSPPVNLKVTEITKDSVSITWEPPLLDGG 16690
Query: 292 AKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
+K KN +R + +AA K++ ++ + V + I L A
Sbjct: 16691 SKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEG--CSYYFRVTAENEYGIGLPAQ 16748
Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
P A V P G+ + +P D SK + M+ +
Sbjct: 16749 TADPIKVAE---VPQPPGKITVDDVTRNSVSLSWTKP---EHDGGSKIIQYIVEMQAKHS 16802
Query: 411 SAFPKFESKPQSQEVKENQT----VKFRC-----------EGLAVMEVA------PSFSS 449
+ + Q V N T FR LAV VA P
Sbjct: 16803 EKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKP 16862
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALP 506
+V GQD ++ + G P P ITW +G P++ T + L I++
Sbjct: 16863 AFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHK 16922
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+D G Y N +GQ + S + +K P P P+ +S
Sbjct: 16923 DDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFDDVS----- 16964
Query: 567 DGSQVTMTVQVSGNPP 582
++ +S NPP
Sbjct: 16965 -----AESITLSWNPP 16975
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21655
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 21656 VYTVEAKNASGSAKAEIKVKVQ 21677
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24161 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24220
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24221 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 665
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23483
Query: 666 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 721
G + L + WL +++ + T F L + + + + G
Sbjct: 23484 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23543
Query: 722 QYEILLKNRVGECSCQVSL 740
Y L++ V EC + +
Sbjct: 23544 SY---LQSEVIECRSSIRI 23559
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1661 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1720
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15749 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15807
Query: 1721 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15808 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15865
Score = 52.4 bits (124), Expect = 4e-06
Identities = 94/441 (21%), Positives = 159/441 (36%), Gaps = 63/441 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V ++ G R ++GRP P +TW K + L A + +E + +++ VN+ D G
Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAG 23141
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVRKE---------VTNVI 279
YT N SGK S + + + S V+E + + E V N I
Sbjct: 23142 KYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYI 23201
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSP------------PWAANSQPQPPRESKLESCKD 327
++ + + CS S P +P S +
Sbjct: 23202 VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 23261
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
P + V+ T S++TL +P G L+ E + R T +P
Sbjct: 23262 VPLVPAKLEVVDVTKSTVTL----AWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23317
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSF 447
+ V S EG++ + +++ E +E T + L V+
Sbjct: 23318 TVLEHTVTSL-------NEGEQYLFRIRAQNEKGVSEPRETVTA-VTVQDLRVLPTIDLS 23369
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCE--AGVAELHIQDA 504
+ K V G+ L + G P P +W G ++ + R T E VA+L I++
Sbjct: 23370 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 23429
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
D G YT +N G S + V + +K P PT PI +
Sbjct: 23430 TIRDTGEYTLELKNVTGTTSETIKVIILDK-------------PGPPTGPI------KID 23470
Query: 565 VMDGSQVTMTVQVSGNPPPEV 585
+D + +T++ + PPE+
Sbjct: 23471 EIDATSITISWE-----PPEL 23486
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1211
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 23943 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 24002
Query: 1212 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1263
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 24003 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 24060
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1321
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 24061 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 24119
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1369
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 24120 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24171
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 25206 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25265
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 25266 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25300
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10911
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 10912 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10959
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P G SV V + W ++ H
Sbjct: 10960 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10997
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1272
+E L +AA EN+ G + DP P G P
Sbjct: 10998 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 11045
Query: 1273 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 11046 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 11105
Query: 1331 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
Y+FRV+A N+ G P + EK P E++V
Sbjct: 11106 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11142
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 21596 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21654
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698
Score = 51.6 bits (122), Expect = 7e-06
Identities = 90/418 (21%), Positives = 158/418 (37%), Gaps = 69/418 (16%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14471
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 14472 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14529
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 14530 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14589
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T
Sbjct: 14590 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV 14645
Query: 386 QPGLGSQDVVSKAANR-----RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAV 440
+ G + VV ++ + P+ ES+P + + QT+ L
Sbjct: 14646 K---GLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRP---VIVKEQTM------LPE 14692
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVA 497
+++ + ++ A G + ++ V G P P +TW Q + Q A
Sbjct: 14693 LDLRGIYQKLVIAKA---GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 14749
Query: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
L+I + + D G Y A N +G+V + VH+ P PT PI
Sbjct: 14750 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14794
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1258
W K K + + H KV G + + EN G +
Sbjct: 20344 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20392
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 20393 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20451
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1348
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 20452 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20484
Score = 51.2 bits (121), Expect = 9e-06
Identities = 55/198 (27%), Positives = 76/198 (38%), Gaps = 39/198 (19%)
Query: 452 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPED 508
KD +E + SV VP + W +P R E V +L +Q+ P D
Sbjct: 2756 KDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSD 2814
Query: 509 HGTYTCLAENALGQVSCSAWV---TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 565
G YT + +GQ+ C A + T+H K+ + E P TA
Sbjct: 2815 AGEYTAV----VGQLECKAKLFVETLHITKTMKNIE-----VPETKTA------------ 2853
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 625
+ +VS P + WL NG EI+ SE F +G H L I ED+ YT
Sbjct: 2854 ------SFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYT 2906
Query: 626 CEAWNSAGEVRTQAVLTV 643
N + A LTV
Sbjct: 2907 FVCGND----QVSATLTV 2920
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1316
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 8628 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8685
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 8686 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8737
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1056 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1114
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 20927 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20986
Query: 1115 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1169
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 20987 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 21038
Query: 1170 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1229
TW + + ++ SE
Sbjct: 21039 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 21064
Query: 1230 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1287
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 21065 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 21115
Query: 1288 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 21116 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21175
Query: 1348 QESELTTVGEKPEEPKDEVEVSD 1370
+ TV E P EV++SD
Sbjct: 21176 TIGPI-TVKELIITP--EVDLSD 21195
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1274
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 21836 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21893
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1332
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 21894 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21953
Query: 1333 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
FRV AIN G + + + ++ P+ +++ +
Sbjct: 21954 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21990
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 24158 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24216
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
TL + + G Y + N VGE L+LQ
Sbjct: 24217 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24251
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7360
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 7361 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7420
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 7421 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7455
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 9227 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9285
Query: 1316 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1370
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 9286 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9343
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 13336 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13395
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G+ E + V V D P PPV T + + P
Sbjct: 13396 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13437
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P II + ++ + K T C+ FR V N E
Sbjct: 13438 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13480
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1279
G + + EN+ G V P G +RS SS
Sbjct: 13481 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13528
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1339
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 13529 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13587
Query: 1340 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
G P SE+T V +D+V D D K
Sbjct: 13588 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13613
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16924
Query: 720 AGQYEILLKNRVGECSCQVSLM 741
GQY I + N VG+ + + ++
Sbjct: 16925 GGQYGITVANVVGQKTASIEIV 16946
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12992
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 12993 DYTITAENSSGSKSATIKLKV 13013
Score = 48.9 bits (115), Expect = 4e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1062 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100
Query: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
P PP S+ + +K TPP I + +++
Sbjct: 14101 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14140
Query: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1241
E+ L W + IQ H+ + + G++ + H G
Sbjct: 14141 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14181
Query: 1242 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 14182 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14236
Query: 1300 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1357
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 14237 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14296
Query: 1358 K--PEEPKDEVEVSDDDEK 1374
P P V+D +K
Sbjct: 14297 AAYPPGPPSNPHVTDTTKK 14315
Score = 48.5 bits (114), Expect = 6e-05
Identities = 92/445 (20%), Positives = 156/445 (35%), Gaps = 76/445 (17%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10915
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANR----SFVRET------KATNSDVRKEVTNVISK 281
+ V N +G ++S ++ + R S +R+ K D +TN + +
Sbjct: 10916 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 10975
Query: 282 ESKLDS-----LEAAAKSKN--CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQ 334
+ S L A +K K+ G + ++ Q R +E+ K P
Sbjct: 10976 RRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPL 11035
Query: 335 TPV--------LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
P + + ++L + + +P G L EE
Sbjct: 11036 HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEE---------------- 11079
Query: 387 PGLGSQDVV--SKAANRRIPMEGQRDSAFPKFESKPQS--QEVKENQTVKFRCEGLAVME 442
G+QD + N + G + +F K ++ + T+ C+ V
Sbjct: 11080 ---GTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPP 11136
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAEL 499
+++ V G +RG PVP W +G I ++ + + L
Sbjct: 11137 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVL 11196
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ L D G Y NA G + + +TV + P PT PI
Sbjct: 11197 TIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD-------------VPGPPTGPI---- 11239
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPE 584
++D + MT +S PP +
Sbjct: 11240 ----NILDVTPEHMT--ISWQPPKD 11258
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 12895 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12953
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 12954 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 13010
Query: 121 LTV 123
L V
Sbjct: 13011 LKV 13013
Score = 48.5 bits (114), Expect = 6e-05
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+ K G+ + GRP P VTW K L AR S+ + +L I V ++D G
Sbjct: 20909 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 20968
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDS 255
Y + NG G+ S+ +S++ LD+
Sbjct: 20969 KYILTIENGVGEPK-SSTVSVKVLDT 20993
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1256 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 23652 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23709
Query: 1314 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 23710 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23767
Score = 48.1 bits (113), Expect = 7e-05
Identities = 88/408 (21%), Positives = 158/408 (38%), Gaps = 69/408 (16%)
Query: 179 RFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
R I GRP P+V W + + + + S+ + +L + VN+ D G Y V N
Sbjct: 15507 RLFVPIKGRPAPEVKWARDHG--ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS 15564
Query: 239 SGKASMSAELSIQGLDSANRSF---VRETKATNS---------DVRKEVTNVISKESKLD 286
SG S SA ++++ LD+ V+E T+ D ++ N I ++ +
Sbjct: 15565 SG--SKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 15622
Query: 287 SLEAAAKSKNCSSP-------QRGGSPPWAANSQPQP----PRESKLESCKDSPRTAP-- 333
+ + NC Q G S + ++ + P E+ ES K S R P
Sbjct: 15623 RKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETA-ESVKASERPLPPG 15681
Query: 334 QTPVLQKTSSSITLQAARVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLG 390
+ ++ T +S++L + + + + LG + G ++ T T GL
Sbjct: 15682 KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATIT-GL- 15739
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSV 450
+ + + R+ + ++ + P+ S P + + + P+F +
Sbjct: 15740 ---IQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---------------LVIPPAFKLL 15781
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPE 507
V+ G+D + G P P +TW + P+ Q R E+ + L I+DA E
Sbjct: 15782 FNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 15841
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
D G Y N+ G+ + V V +K P PT P+
Sbjct: 15842 DVGHYVVKLTNSAGEAIETLNVIVLDK-------------PGPPTGPV 15876
Score = 48.1 bits (113), Expect = 7e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 19008 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 19050
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 19051 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 19108
Query: 249 SIQGLD 254
+I LD
Sbjct: 19109 TIIVLD 19114
Score = 48.1 bits (113), Expect = 7e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 19362 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19417
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 19418 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19477
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 19478 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1631 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1690
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 26123 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26182
Query: 1691 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 26183 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26241
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ IS V D+ Y+ NS G+ L ++
Sbjct: 26242 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279
Score = 47.8 bits (112), Expect = 1e-04
Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 14/132 (10%)
Query: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FE 603
++ S+ F + + ++++G VT ++SG P P++ W +G I+ E + F
Sbjct: 1237 ISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFL 1296
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS------- 656
Q G + SL I V PED G YT A N G L V+ P +I
Sbjct: 1297 QDG-RASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSR 1355
Query: 657 ----KPRSVTAS 664
PRSV+ S
Sbjct: 1356 IRSLSPRSVSRS 1367
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1739
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 1740 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1194 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1253
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 7143 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Query: 1254 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1307
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7260
Query: 1308 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 7261 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7320
Query: 1367 EV 1368
+V
Sbjct: 7321 DV 7322
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
VT +G +V + G P P++ WL+DG L K++ + E+ TL +K + H
Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPL-KESEFVRFSKTENKITLSIKNAKKEHG 21259
Query: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRG 753
G+Y ++L N V C V + + + P+G
Sbjct: 21260 GKYTVILDNAV--CRIAVPITVITLGPPSKPKG 21290
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 506 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 561
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 21548 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21597
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 21598 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21654
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE 645
G YT EA N++G + + + VQ+
Sbjct: 21655 GVYTVEAKNASGSAKAEIKVKVQD 21678
Score = 47.4 bits (111), Expect = 1e-04
Identities = 117/571 (20%), Positives = 206/571 (36%), Gaps = 81/571 (14%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
E P F KL E C+++ V W K + PS + S+ ++
Sbjct: 5288 EADPYFTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI 5345
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS---ANRSFVRET-----KATNS 269
L+I + D G Y C KA+++ E + ++ FV ET + +
Sbjct: 5346 LKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEP 5405
Query: 270 DVR---KEVTNVISKESKLDSLEAAAKS----KNCSSPQRGGSPPWAANSQPQPPRESK- 321
DV K ++ + +E K NC G AAN++ + K
Sbjct: 5406 DVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKE 5465
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
L +P + V +K + + +R +P+ G +G++R
Sbjct: 5466 LPLIFITPLS--DVKVFEKDEAKFECEVSR-EPKTFRWLKGTQEITGDDR---------- 5512
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
F + G V+ AA D A FE++ ++ + K EG+ +
Sbjct: 5513 FELIKDGTKHSMVIKSAA--------FEDEAKYMFEAE------DKHTSGKLIIEGIRLK 5558
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 501
+ P LKD E + V + + R+ W N Q + RS + +
Sbjct: 5559 FLTP-----LKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSM 5604
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
QD T+ L+ + Q+ A SE L V P F L
Sbjct: 5605 QDEGKTHSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQ 5653
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D ++ +V + ++S P V W +G EI+ S++ + G + L +++ D
Sbjct: 5654 DYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDI 5712
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 681
G YTC+ G +T L +++ + + SV ++ I+ D
Sbjct: 5713 GQYTCD----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI- 5763
Query: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 712
+W G+AL + T E+ + + +LVL
Sbjct: 5764 HANWKLKGEALLQ-TPDCEIKEEGKIHSLVL 5793
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 6917 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6975
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 6976 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 7030
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 563
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 12874 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12933
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 620
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 12934 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12990
Query: 621 TGTYTCEAWNSAG 633
+G YT A NS+G
Sbjct: 12991 SGDYTITAENSSG 13003
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 13621 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13680
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 13681 YTITLKNVAGTKEGTISIKVVG 13702
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17995
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 17996 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21619
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21620 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1318
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 22868 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22926
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 22927 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22970
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 23048 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 23105
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 23106 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23162
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)
Query: 919 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 976
++++ + +GS E + VES +S + S V K + +A ++
Sbjct: 4266 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4325
Query: 977 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
K + KP E + +S E ++V V + G + P L
Sbjct: 4326 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4375
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1095
D EG + L +++ + W K + + + Q+ + ++ I+K ED
Sbjct: 4376 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4433
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
+G Y C A ND+G+ S ++TV K
Sbjct: 4434 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4458
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+ AP K E +V G + ++ + W K ++I ES+
Sbjct: 4459 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4508
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ +S+ S L IL + CG YT N+ GS LTV
Sbjct: 4509 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4551
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)
Query: 683 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 741
V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L
Sbjct: 4397 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4455
Query: 742 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 801
+ +A + R EP ++ G + ++R W G+ + E D +R
Sbjct: 4456 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4511
Query: 802 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 848
+L+ +V + ++T +A + L G+K K L E K
Sbjct: 4512 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4569
Query: 849 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 894
P E++ ++ L++ + +PK ++ KV P ++V+ +V ++
Sbjct: 4570 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4627
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 954
K P P KVP KPA P LPA E A+ P +P+
Sbjct: 4628 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4673
Query: 955 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1014
PV P K A E KP G P + + + ++ + + G
Sbjct: 4674 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4728
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1068
+ + + F ++++D+ + E G + +C VS P+T I W +G
Sbjct: 4729 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4785
Query: 1069 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 4786 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4839
Score = 47.0 bits (110), Expect = 2e-04
Identities = 104/465 (22%), Positives = 165/465 (35%), Gaps = 67/465 (14%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 8687 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8741
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8800
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 8801 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8860
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 8861 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8920
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 8921 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8976
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
PT + + D + R+ + + P Q+ + T+K R
Sbjct: 8977 CPTTSFLVENLDE-HQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL------ 9029
Query: 442 EVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA------ 494
SV D ++ G+ + V G P+P+I W N I+ +
Sbjct: 9030 -------SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9082
Query: 495 ---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
EL I A+ ED GTYT A N LG V + V V+++ S
Sbjct: 9083 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9127
Score = 47.0 bits (110), Expect = 2e-04
Identities = 109/532 (20%), Positives = 188/532 (35%), Gaps = 89/532 (16%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 10456 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10514
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V +G + D + +P +
Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM---VISWKPPL-----D 10566
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEI 220
+K+ ++++ ++G+ W+ + + + +VS + + I
Sbjct: 10567 DGGSKITNYIIEKKEVGKD------------VWMPVTSASAKTTCKVSKLLEGKDYIFRI 10614
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVR 272
H N G+ LV + SM A+ + D+ ++ V E ++ D
Sbjct: 10615 HAENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 10667
Query: 273 KEVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQP 316
K +TN I ++ + S A +K+ C R + P P
Sbjct: 10668 KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSP 10727
Query: 317 PRE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERK 372
P + +K K SP P+ S +T Q R + G V G+E
Sbjct: 10728 PSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW 10787
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKF---------ESKPQSQ 423
R A P + P + + G RD KF ES P
Sbjct: 10788 RRANHTPESCP----------------ETKYKVTGLRDGQTYKFRVLAVNAAGESDPA-- 10829
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
V E VK R E ++ A ++ ++ + G L ++G P P++TW +
Sbjct: 10830 HVPEPVLVKDRLEPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDR 10885
Query: 484 PIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
AR ++L I++A ED G Y+ EN G + S V V +K
Sbjct: 10886 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10937
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1042 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1100
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 25209 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25268
Query: 1101 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1159
C ND G+ ++ V + + RR T+KK K
Sbjct: 25269 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25308
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1216
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 25309 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25368
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1265
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 25369 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25428
Query: 1266 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
G +IR S + TL W DG +IEI +
Sbjct: 25429 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25479
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 25480 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25536
Query: 1376 PEVDYRTVTI 1385
+ R I
Sbjct: 25537 IDKTLRMAEI 25546
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ + + +G A FE V G P P VTW + + + + + + G+ + +
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
++ ED G Y C+A N G EL V P +K+ +
Sbjct: 3760 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3819
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PAVE S + AT + ++K + + +++ + L +PL
Sbjct: 3820 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3874
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
S+ E++ + + + C +NGS S L +Q + S ++F
Sbjct: 3875 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3923
Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ ET+A SD K + +S E +++SL + P+ G P
Sbjct: 3924 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3977
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
S +PP S L S + +P+ + T+ +TLQ Q
Sbjct: 3978 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 4020
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 13615 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13673
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 13674 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13702
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1648 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1702
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26309 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26368
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26369 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26419
Query: 1763 K 1763
+
Sbjct: 26420 E 26420
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVD 1119
D G YK + G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 6000 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 6055
Query: 1745 CSLIISDVCGDDDAKYTCK 1763
L+I+ DD+A+Y+C+
Sbjct: 6056 RILVINKCLLDDEAEYSCE 6074
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 496
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 21585 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21641
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
L ++DA + G YT A+NA G V V +
Sbjct: 21642 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21678
Score = 45.8 bits (107), Expect = 4e-04
Identities = 88/439 (20%), Positives = 162/439 (36%), Gaps = 71/439 (16%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 25857 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25916
Query: 311 --NSQPQPPRESKLESCKDSP---RTAPQTP--VLQKTSSSITLQAARVQPEPRAPGLGV 363
S+PQP E + ++ + SP RT P++P V + S S ++AR R +
Sbjct: 25917 LIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKA 25976
Query: 364 L---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
+ E + +P T + + + + R+P GQ +SKP
Sbjct: 25977 ALKTQKTSERKYEVLSQQPFTLDH------APRITLRMRSHRVPC-GQNTRFILNVQSKP 26029
Query: 421 QSQ--------EVKENQTVKF-RCEGLAVME--------------VAPSFSSVLKDCAVI 457
++ E++E+ + + G+ +E V ++ D A +
Sbjct: 26030 TAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 26089
Query: 458 E--GQDFVLQCSVR-GTPVPRITWLLNGQPIQYARST------CEAGVAELHIQDALPED 508
+ G D+ S R VPR + + YA S+ EA + ++ + E
Sbjct: 26090 DVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTET 26149
Query: 509 HGTYTCLAENALGQVSCSAWV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+ + +A ++ +A ++ EK ++RK + L A L + V
Sbjct: 26150 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVY 26201
Query: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 626
+G + G P P V WL G + S + + I V D G Y+
Sbjct: 26202 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 26261
Query: 627 EAWNSAGEVRTQAVLTVQE 645
NS G+ + LT+Q+
Sbjct: 26262 VVENSEGKQEAEFTLTIQK 26280
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 17951 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 18010
Query: 625 TCEAWNSAG-EVRTQAVLTVQEP 646
T A NSAG +V+ +++P
Sbjct: 18011 TVTATNSAGTATENLSVIVLEKP 18033
Score = 45.1 bits (105), Expect = 6e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1159 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1215
P PP A P++ + +R E G I W+ K R I +
Sbjct: 22465 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22519
Query: 1216 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 22520 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22578
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1329
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 22579 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22638
Query: 1330 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 22639 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22677
Score = 44.7 bits (104), Expect = 8e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1317
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 12817 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12876
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 12877 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12928
Score = 44.7 bits (104), Expect = 8e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN-EDVFTLVLKKVQPWHAGQYE 724
G SV + I+G P PT+ W +D K L T ++N D+ ++++K ++G YE
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYE 20572
Query: 725 ILLKNRVGECSCQVSLML 742
+ L+N +G S + + +
Sbjct: 20573 LKLRNAMGSASATIRVQI 20590
Score = 44.3 bits (103), Expect = 0.001
Identities = 183/961 (19%), Positives = 338/961 (35%), Gaps = 154/961 (16%)
Query: 180 FSCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
F+C I + P + W KG +P +P+ + + L+I +D+ Y +
Sbjct: 4953 FACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 5011
Query: 238 GSGKASMS-AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
A ++ E ++ L + E ++ + D + I + KL E S
Sbjct: 5012 KRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD-IPGQWKLKG-ELLRPSPT 5069
Query: 297 CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP 356
C GG + L ++ TA T + ++ L+ V
Sbjct: 5070 CEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERR 5129
Query: 357 RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQR------D 410
+A VL+ P D++ + I +G++ D
Sbjct: 5130 QARFECVLTREANVIWSKGP----------------DIIKSSDKFDIIADGKKHILVIND 5173
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 470
S F + + EV+ +T L V + F S L+D V EG+ C +
Sbjct: 5174 SQFD--DEGVYTAEVEGKKT----SARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSH 5227
Query: 471 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
+ + W N + +R+ + + H + + E L +S
Sbjct: 5228 EKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQ 5274
Query: 531 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
V E S+ + + L P F L D ++ ++T+ +VS + P V W +
Sbjct: 5275 VKELSSTAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKD 5325
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN--SAGEVRTQA-VLTVQEPH 647
G EI S + + G + L I++ +D G Y C+ + V +A ++ V++P
Sbjct: 5326 GEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPL 5385
Query: 648 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNE 705
G + F+ + L + P VH W G+ L E++++
Sbjct: 5386 YGVEV-FVGETAHFEIELSE-------------PDVHGQWKLKGQPLTASPD-CEIIEDG 5430
Query: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR-------- 752
L+L Q G+ N + +V + S + +
Sbjct: 5431 KKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECE 5490
Query: 753 -GREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR 811
REP + L G + G DR+ ++ G + ++ ED + +
Sbjct: 5491 VSREPKTFRWLKGT---QEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED-- 5543
Query: 812 QHTE-----EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQR 862
+HT E IR + + L +D+ K+ V T LS D+++ + + N QR
Sbjct: 5544 KHTSGKLIIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQR 5595
Query: 863 QVKPKTVS-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKK 921
++VS ++E K HS + F+ L+ TS+ V + + K
Sbjct: 5596 LHTTRSVSMQDEGKTHS---ITFKD-LSIDDTSQIRVEAMG-------------MSSEAK 5638
Query: 922 LPAENGSS--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLK 979
L G + + + VE + + + S PV K + +KP NA
Sbjct: 5639 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------ 5692
Query: 980 PMGNAKPDENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
+K+ K+ LKK +K+D+ GT + + + + L
Sbjct: 5693 ----------IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLH 5742
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
V V E + + ++S D W L G+ L T + +EG + S+ + +
Sbjct: 5743 SVEVMETETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQT 5801
Query: 1097 G 1097
G
Sbjct: 5802 G 5802
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11204
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 11205 DTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 532 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 15753 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15812
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 649
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 15813 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15872
Query: 650 TQP 652
T P
Sbjct: 15873 TGP 15875
Score = 44.3 bits (103), Expect = 0.001
Identities = 81/396 (20%), Positives = 141/396 (35%), Gaps = 56/396 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 18745 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18802
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 18803 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18860
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 18861 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18920
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 18921 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18980
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
GL G + V AA R P + E+K + + F +
Sbjct: 18981 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVI---ARDIEIKPSVELPFHTFNVKAR 19037
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAE 498
E + +G P + W +GQ ++ + V
Sbjct: 19038 E------------------QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS 19079
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
L I++A ED GTY N+ G ++ + V ++
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 19115
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 12527 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12585
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSG 12606
Score = 43.9 bits (102), Expect = 0.001
Identities = 112/518 (21%), Positives = 191/518 (36%), Gaps = 68/518 (13%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 22687 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22744
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22803
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 22804 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22863
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 22864 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22923
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 22924 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22966
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 22967 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 23024
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
R F +G + AA + ++G + S+ + E + V+ R E
Sbjct: 23025 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSE----------YSESIAEIEPVE-RIE 23070
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 496
+ +E+A + K + G L SV G P P ITW G +
Sbjct: 23071 -IPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES 23126
Query: 497 AELHIQDALPE-DHGTYTCLAENALGQVSCSAWVTVHE 533
L I D + D G YT AEN G+ S + V V++
Sbjct: 23127 YSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD 23164
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 9719 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9772
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 9773 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9828
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 9829 NLGTASKEMRLNVLG 9843
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1750
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9754 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9812
Query: 1751 DVCGDDDAKYTCKAVNSLGEAT 1772
D YT AVN+LG A+
Sbjct: 9813 QSRRSDTGLYTITAVNNLGTAS 9834
Score = 43.1 bits (100), Expect = 0.002
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11656
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12516 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12575
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12576 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1718
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16145 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16201
Query: 1719 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16202 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16260
Query: 1779 V 1779
V
Sbjct: 16261 V 16261
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1321
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 19611 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19669
Query: 1322 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1352
V+ L EY++RV A N G S PS+ S L
Sbjct: 19670 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19702
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1025 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1081
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
+++++ ED+G Y V
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401
Query: 1262 PDP 1264
P
Sbjct: 2402 ITP 2404
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1691 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1744
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4745 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4802
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+I DV D +YTC E T TA+L+VE +
Sbjct: 4803 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 17204 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17262
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 17263 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17320
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKV 17343
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 990 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1038
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021
Query: 1039 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1098
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080
Query: 1099 YKCVAKNDAGQAE 1111
Y VA + A+
Sbjct: 3081 YTVVAGGNVSTAK 3093
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 13331 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13390
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 13391 KYILTLENSCGK 13402
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14767
Query: 628 AWNSAGEVRTQAVLTVQ 644
A N GEV V+T+Q
Sbjct: 14768 ARNIVGEVGD--VITIQ 14782
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 507
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 16178 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16237
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 564
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 16238 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16284
Query: 565 -----VMDGSQVTMTVQVSGNPPPEVIW 587
+ DG + V ++W
Sbjct: 16285 AWKPPLQDGGSDIINYIVERRETSRLVW 16312
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16857 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16911
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+L I + DD +Y N +G+ T + E++
Sbjct: 16912 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16946
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 19038 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19096
Query: 727 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
+ N G + +++++ + P + SC+ +
Sbjct: 19097 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19132
Score = 42.4 bits (98), Expect = 0.004
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 520 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK----VMDGSQVTMTV 575
+GQ V+ K S SE + + P + L+ DLK + G+ + + V
Sbjct: 23037 MGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMV 23096
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
VSG PPP + W G I + + + L + +V D G YT EA N +G+
Sbjct: 23097 SVSGRPPPVITWSKQG--IDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23154
Query: 636 RTQAVLTVQE 645
++ V +
Sbjct: 23155 SATVLVKVYD 23164
Score = 42.0 bits (97), Expect = 0.005
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1089
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5972
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
PED Y C DA + SC + V
Sbjct: 5973 DCTPEDIKTYTC----DAKDFKTSCNLNV 5997
Score = 42.0 bits (97), Expect = 0.005
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 6087 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6145
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 6146 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6176
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 6177 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6226
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 6227 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6264
Score = 42.0 bits (97), Expect = 0.005
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 11136 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11195
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
L I+ DTG Y N+AG LTV
Sbjct: 11196 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12991
Query: 721 GQYEILLKNRVGECSCQVSL 740
G Y I +N G S + L
Sbjct: 12992 GDYTITAENSSGSKSATIKL 13011
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 21996 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 22053
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 22054 YTLTVENNSGSKSITFTVKV 22073
Score = 42.0 bits (97), Expect = 0.005
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 570
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 22642 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22692
Query: 571 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 630
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 22693 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22752
Query: 631 SAGEVRTQAVLTVQEPHDGTQP 652
++G T+AV + + D P
Sbjct: 22753 ASG---TKAVSVMVKVLDSPGP 22771
Score = 42.0 bits (97), Expect = 0.005
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 22664 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22713
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22768
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6150
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1793
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6151 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6198
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 17228 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17285
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 17286 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17341
Query: 122 TV 123
V
Sbjct: 17342 KV 17343
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19881
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 19882 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19920
Score = 41.6 bits (96), Expect = 0.007
Identities = 34/133 (25%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
TCE Q +E V K L PV T+G + T + P
Sbjct: 21145 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV---TIGPITVKELIITPEVDLSDIPG--- 21198
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
+V V+ G G+P+P ++WLK +PL+ S V S+ L I
Sbjct: 21199 ---AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAK 21255
Query: 225 QDDVGVYTCLVVN 237
++ G YT ++ N
Sbjct: 21256 KEHGGKYTVILDN 21268
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1744
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26955 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 27013
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+LII DV D YT N G + T + + ++
Sbjct: 27014 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 27051
Score = 41.2 bits (95), Expect = 0.009
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 8012 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 8071
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 8072 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8107
Score = 41.2 bits (95), Expect = 0.009
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 501
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 8015 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 8074
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++ D G YT EN LG + S V V
Sbjct: 8075 PKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 41.2 bits (95), Expect = 0.009
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11201
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D +Y N+ G T L V
Sbjct: 11202 LRRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18404
Query: 721 GQYEILLKNRVGECSCQVSL 740
GQY + L N G S +++
Sbjct: 18405 GQYILKLSNVGGTKSIPITV 18424
Score = 41.2 bits (95), Expect = 0.009
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 22685 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22744
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y KN +G S V V D+P
Sbjct: 22745 KYTLTVKNASGTKAVSVMVKVLDSP 22769
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 535 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7358
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 7359 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7406
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7323 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7381
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y +AVN G AT E+ V
Sbjct: 7382 KRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1320
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 7712 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7770
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSE 1345
V L Y FRV A N G S+
Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSD 7795
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 12527 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12585
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 12586 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 16181 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16240
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 16241 NYILKAKNVAGERSVTVNVKV 16261
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 16869 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16927
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 16928 YGITVANVVGQKTASIEI 16945
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17996
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + DD KYT A NS G AT +IV
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 19039 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 19098
Query: 630 NSAGEVRTQAVLTV 643
NSAG + + V
Sbjct: 19099 NSAGSITVPITIIV 19112
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 642 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 688
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 19395 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19454
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 19455 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19504
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5915 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5972
Query: 1751 DVCGDDDAKYTCKA 1764
D +D YTC A
Sbjct: 5973 DCTPEDIKTYTCDA 5986
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11604
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 11605 GKYIISAKNSSGHAQ 11619
Score = 40.4 bits (93), Expect = 0.016
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCL 515
GQ + V+G P P ITW G+ + + + EL I++A+ DHG Y
Sbjct: 11551 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11610
Query: 516 AENALGQVSCSAWVTVHEK 534
A+N+ G SA V V ++
Sbjct: 11611 AKNSSGHAQGSAIVNVLDR 11629
Score = 40.0 bits (92), Expect = 0.020
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 10827 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10886
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 10887 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 529 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 587
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 16832 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16891
Query: 588 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 646
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 16892 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16951
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 506
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y N G S V V ++ P P P+ + G++
Sbjct: 18402 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18443
Score = 40.0 bits (92), Expect = 0.020
Identities = 20/73 (27%), Positives = 29/73 (39%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G V + + G PPP V W + + + E + L I +V DTG Y
Sbjct: 20914 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 20973
Query: 628 AWNSAGEVRTQAV 640
N GE ++ V
Sbjct: 20974 IENGVGEPKSSTV 20986
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
G AKF ++ P + W + G+ I + C IR + SL I D G+
Sbjct: 4476 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4531
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
YTC+A+N G+ T LTV G+ V K L +R P E
Sbjct: 4532 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4574
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1668 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5619 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5677
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5678 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5717
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 7300 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7359
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 7360 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 39.7 bits (91), Expect = 0.027
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 11148 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11207
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 11208 EYQITVSNAAGSKTVAVHLTV 11228
Score = 39.7 bits (91), Expect = 0.027
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 19/124 (15%)
Query: 446 SFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAG----VAELH 500
S +D V+ G+ F L+ V G P+P I WL + I+ + + CE A L
Sbjct: 17254 SMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES-ARCEIKNTDFKALLI 17312
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
++DA+ D G Y A N G S V V ++ P P P+ + G+
Sbjct: 17313 VKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-------------PGPPEGPVQVTGV 17359
Query: 561 SDLK 564
+ K
Sbjct: 17360 TSEK 17363
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 17621 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17680
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 17681 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17737
Query: 121 LTV 123
+ V
Sbjct: 17738 VKV 17740
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23141
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y A+N +G+ + V V D P
Sbjct: 23142 KYTIEAENQSGKKSATVLVKVYDTP 23166
Score = 39.3 bits (90), Expect = 0.035
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 710
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 711 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 770
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 771 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 824
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 825 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 884
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 885 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 936
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPA 963
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 8004 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 8063
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
D + L + D YT N LG AT + + V
Sbjct: 8064 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 8104
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 506
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 8737 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8796
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 8797 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8851
Query: 567 DGSQVT 572
GS++T
Sbjct: 8852 GGSEIT 8857
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 716
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9510
Query: 717 PWHAGQYEILLKNRVGE--CSCQVSLM 741
H G+Y I KN+ G+ +C+V +M
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVM 9537
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 599 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 16123 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16179
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 16180 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16235
Query: 717 PWHAGQYEILLKNRVGECSCQVSL 740
+G Y + KN GE S V++
Sbjct: 16236 RVDSGNYILKAKNVAGERSVTVNV 16259
Score = 38.9 bits (89), Expect = 0.045
Identities = 56/243 (23%), Positives = 87/243 (35%), Gaps = 50/243 (20%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 5092 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5140
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 5141 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5185
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 5186 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5222
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V S
Sbjct: 5223 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSST 5281
Query: 242 ASM 244
A +
Sbjct: 5282 AQL 5284
Score = 38.9 bits (89), Expect = 0.045
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
FA L V V E + RF C +T + V W KG ++ S + + +L I+
Sbjct: 5116 FAVPLKDVTVPERRQARFECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVIND 5173
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
DD GVYT V GK + SA L + G+
Sbjct: 5174 SQFDDEGVYTAEV---EGKKT-SARLFVTGI 5200
Score = 38.9 bits (89), Expect = 0.045
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11605
Query: 623 TYTCEAWNSAGEVRTQAVLTV 643
Y A NS+G + A++ V
Sbjct: 11606 KYIISAKNSSGHAQGSAIVNV 11626
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 1/124 (0%)
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 687
A N+ G + V E + P I P +T G+ + I + G P PT W +
Sbjct: 12503 ARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-K 12561
Query: 688 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
G+ + H V + + L++K V +G Y + +N G + ++ +++ ++
Sbjct: 12562 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12621
Query: 748 RALP 751
P
Sbjct: 12622 PPQP 12625
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 20908 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20966
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 20967 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 21000
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 21206 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21265
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
+NA+ +++ V L P PSKP PI
Sbjct: 21266 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21292
Score = 38.5 bits (88), Expect = 0.059
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1146 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 38.5 bits (88), Expect = 0.059
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 545 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 8720 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8778
Query: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+ GT+ L I++ +D G Y A NS G
Sbjct: 8779 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8811
Score = 38.5 bits (88), Expect = 0.059
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 11839 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11896
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 11897 SDGGKYVVTATNTAGS 11912
Score = 38.5 bits (88), Expect = 0.059
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 15776 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15834
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15889
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 15890 ---WG--PPKY 15895
Score = 38.5 bits (88), Expect = 0.059
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17260 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17318
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y +A N G
Sbjct: 17319 IDGGQYILRASNVAG 17333
Score = 38.5 bits (88), Expect = 0.059
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 22285 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22344
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 22345 RYFLTLENTAGVKTFSVTVVVIG 22367
Score = 38.1 bits (87), Expect = 0.078
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 472 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 7953 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7996
Query: 531 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 589
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 7997 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 8050
Query: 590 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 648
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 8051 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 8108
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 702
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 8109 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8158
Query: 703 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
E+ + +K + P + + N+VG
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8188
Score = 37.7 bits (86), Expect = 0.10
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 551 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 603
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 9023 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 9082
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
+ + L I + ED GTYT A N G V
Sbjct: 9083 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 9114
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 15099 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15158
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 15159 AYTLTATNPGGFA 15171
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 18331 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18390
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 18391 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18426
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 548 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 594
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 19399 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19458
Query: 595 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+E L +++ DTG Y N AG
Sbjct: 19459 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19497
Score = 37.7 bits (86), Expect = 0.10
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 562 DLKVMDGSQVTMTV--------QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
DL + G+QVT+ + G P P + WL +G ++ESE F + + +L I
Sbjct: 21192 DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSI 21251
Query: 614 QEVFPEDTGTYT 625
+ E G YT
Sbjct: 21252 KNAKKEHGGKYT 21263
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 21598 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21657
Query: 1100 KCVAKNDAGQAECSCQVTVDDAP 1122
AKN +G A+ +V V D P
Sbjct: 21658 TVEAKNASGSAKAEIKVKVQDTP 21680
Score = 37.7 bits (86), Expect = 0.10
Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 8/188 (4%)
Query: 595 QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT---VQEPH-DG 649
Q+ DF E T Q + ++ + + + +A N AG + + ++EP +
Sbjct: 22214 QKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22273
Query: 650 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 709
T + +T G I I+G P P V W + L K+T + +D T
Sbjct: 22274 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTT 22332
Query: 710 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARAL-PRGREPASCED-LCGGGV 767
L +K +G+Y + L+N G + V++++ P S E + G
Sbjct: 22333 LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGE 22392
Query: 768 GADGGGSD 775
DGGG++
Sbjct: 22393 PKDGGGTE 22400
Score = 37.7 bits (86), Expect = 0.10
Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
GS T+ V +SG P P+V W ++E++ + +L +++ D+G Y
Sbjct: 22290 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22349
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
N+AG V+T +V V G ++ P V++ +S ++S
Sbjct: 22350 LENTAG-VKTFSVTVVVIGRPGP----VTGPIEVSSVSAESCVLS 22389
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1756
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8798
Query: 1757 DAKYTCKAVNSLGEATCTAELIV 1779
+Y A NS G A + V
Sbjct: 8799 HGRYVITATNSCGSKFAAARVEV 8821
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 6/123 (4%)
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ +A N+AG + A + + P I + G +V I I G PFPT+
Sbjct: 9717 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 9776
Query: 684 HWLR------DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 737
W + D K H L +D TLV+ + + G Y I N +G S +
Sbjct: 9777 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9836
Query: 738 VSL 740
+ L
Sbjct: 9837 MRL 9839
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11604
Query: 721 GQYEILLKNRVG 732
G+Y I KN G
Sbjct: 11605 GKYIISAKNSSG 11616
Score = 37.4 bits (85), Expect = 0.13
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 12938 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12997
Query: 516 AENALGQVSCSAWVTVHEK 534
AEN+ G S + + V +K
Sbjct: 12998 AENSSGSKSATIKLKVLDK 13016
Score = 37.4 bits (85), Expect = 0.13
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 16166 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16217
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 16218 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16276
Query: 139 TLGDR 143
++
Sbjct: 16277 VTAEK 16281
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1671 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19795 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19853
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19854 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19904
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 20110 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20168
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 20169 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 21601 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21659
Query: 726 LLKNRVGECSCQVSLMLQNSSARAL 750
KN G ++ + +Q++ + +
Sbjct: 21660 EAKNASGSAKAEIKVKVQDTPGKVV 21684
Score = 37.0 bits (84), Expect = 0.17
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1009 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1068
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1126
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893
Query: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949
Query: 1187 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1221
EL K + IT +K RK+ + E + K +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009
Query: 1222 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1271
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1331
WY + IE D W E C ++D+ +
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101
Query: 1332 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1382
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161
Query: 1383 VTINTEQKVSDFY 1395
E D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 10167 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10224
Query: 628 AWNSAGEVRTQAVLTV 643
A N AGE + ++ V
Sbjct: 10225 AKNEAGERKKTIIVDV 10240
Score = 37.0 bits (84), Expect = 0.17
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1750
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11541 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11597
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA 1775
+ D KY A NS G A +A
Sbjct: 11598 EAVRADHGKYIISAKNSSGHAQGSA 11622
Score = 37.0 bits (84), Expect = 0.17
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1680 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1733
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11815 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11874
Query: 1734 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++ D + S ++ D KY A N+ G A + V
Sbjct: 11875 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 37.0 bits (84), Expect = 0.17
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 12536 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12595
Query: 623 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 654
Y+ A NS+G + + V + QP F
Sbjct: 12596 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12627
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16636
Query: 1758 AKYTCKAVNSLG 1769
KYT NS G
Sbjct: 16637 GKYTLTLENSSG 16648
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1689 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20556
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
S++I D + Y K N++G A+ T
Sbjct: 20557 SILIKDADRLNSGCYELKLRNAMGSASAT 20585
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 20510 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20569
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 20570 CYELKLRNAMGSA--SATIRVQILD 20592
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 6610 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6669
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 6670 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6714
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9814
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 9815 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9843
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 12244 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12302
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y+ +VN +G+ ++ + +
Sbjct: 12303 KYSLTLVNPAGEKAVFVNVRV 12323
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 574
A+N G +S + T + K EY P PT L + G + +
Sbjct: 13978 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 14028
Query: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 14029 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 14088
Query: 635 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
+TV + P IS + A+L
Sbjct: 14089 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 14119
Score = 36.6 bits (83), Expect = 0.23
Identities = 18/66 (27%), Positives = 29/66 (43%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + VSG PPP + W +G E++ + + +L ++ D+G YT
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15163
Query: 628 AWNSAG 633
A N G
Sbjct: 15164 ATNPGG 15169
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 20116 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20175
Query: 625 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 656
A NS+G + ++ + P T P IS
Sbjct: 20176 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20208
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1674 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22259 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22317
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22318 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22365
Score = 36.2 bits (82), Expect = 0.29
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1007 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 5795 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5853
Query: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 5854 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5899
Score = 36.2 bits (82), Expect = 0.29
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 17262 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17320
Query: 720 AGQYEILLKNRVGECSCQVSL 740
GQY + N G S V++
Sbjct: 17321 GGQYILRASNVAGSKSFPVNV 17341
Score = 36.2 bits (82), Expect = 0.29
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 718
++VT G S+ + +++G P P + W + G L + E L++ KV +
Sbjct: 23082 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 23138
Query: 719 HAGQYEILLKNRVGECSCQV 738
AG+Y I +N+ G+ S V
Sbjct: 23139 DAGKYTIEAENQSGKKSATV 23158
Score = 35.8 bits (81), Expect = 0.38
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P T L V +EG + + IT + V W N + + + L I
Sbjct: 4368 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4425
Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
VN +D G Y C +N SGK + SA+L++
Sbjct: 4426 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4456
Score = 35.8 bits (81), Expect = 0.38
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 8979 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 9023
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 9024 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 9073
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 9074 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9133
Query: 261 VRETKA 266
V + KA
Sbjct: 9134 VTDIKA 9139
Score = 35.8 bits (81), Expect = 0.38
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 11153 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11211
Query: 726 LLKNRVGECSCQVSL 740
+ N G + V L
Sbjct: 11212 TVSNAAGSKTVAVHL 11226
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 14002 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14061
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 14062 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 14097
Score = 35.8 bits (81), Expect = 0.38
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 16582 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16638
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 16639 YTLTLENSSGTKSAFVTVRV 16658
Score = 35.8 bits (81), Expect = 0.38
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + T SL
Sbjct: 19023 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 19081
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 19082 IKEASKEDVGTYELCVSNSAGS--ITVPITI 19110
Score = 35.8 bits (81), Expect = 0.38
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1713 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20980
Score = 35.8 bits (81), Expect = 0.38
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1073
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 26943 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 27002
Query: 1074 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ L ++ I +D GLY N+ G + + +
Sbjct: 27003 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048
Score = 35.4 bits (80), Expect = 0.50
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 6093 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6151
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1150
A ED G Y C R P S +D
Sbjct: 6152 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6170
Query: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 6171 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6220
Query: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 6221 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6267
Score = 35.4 bits (80), Expect = 0.50
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 10455 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10514
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 10515 GKYCVVVENSTGSRKGFCQVNV 10536
Score = 35.4 bits (80), Expect = 0.50
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 607
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 11828 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11885
Query: 608 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+ + D G Y A N+AG A + V
Sbjct: 11886 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 35.4 bits (80), Expect = 0.50
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 571
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 17221 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17271
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 17272 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17331
Query: 632 AG 633
AG
Sbjct: 17332 AG 17333
Score = 35.4 bits (80), Expect = 0.50
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---E 493
G V+++ ++ V+K A G L+ + G P P I W + + +Q C
Sbjct: 20496 GGPVIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENT 20552
Query: 494 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
+A + I+DA + G Y NA+G S + V + +K
Sbjct: 20553 TDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20593
Score = 35.4 bits (80), Expect = 0.50
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 23774 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23831
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 23832 TYDLVLENKCGKKAVYIKVRVIG 23854
Score = 35.4 bits (80), Expect = 0.50
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1747
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 26002 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 26059
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
I D DD Y N GEA+ A L V
Sbjct: 26060 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5470 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5527
Query: 1751 DVCGDDDAKYTCKA 1764
+D+AKY +A
Sbjct: 5528 SAAFEDEAKYMFEA 5541
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10218
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 10219 GVYSLLAKNEAGE 10231
Score = 35.0 bits (79), Expect = 0.66
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 12246 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12301
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 12302 GKYSLTLVNPAGEKAVFVNVRV 12323
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12933 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12991
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
YT A NS G + T +L V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013
Score = 35.0 bits (79), Expect = 0.66
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 546 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 13600 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13659
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 652
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 13660 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13710
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 13999 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 14048
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 14049 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 14087
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 20113 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20171
Query: 720 AGQYEILLKNRVGECSCQVSLML 742
AG+YEI N G +++++
Sbjct: 20172 AGRYEITAANSSGTTKAFINIVV 20194
Score = 34.7 bits (78), Expect = 0.86
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 623 TYTCEAWNSAGE----VRTQAVLTVQEPHDGTQPWFISKP---------RSVTASLGQSV 669
TYT + E VR + + EP T P P S+ G +
Sbjct: 8266 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEI 8325
Query: 670 LISCAIAGDPFPTVHWLRD 688
+ +I+G P+PT+ W++D
Sbjct: 8326 ALDASISGSPYPTITWIKD 8344
Score = 34.7 bits (78), Expect = 0.86
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 16186 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16245
Query: 628 AWNSAGE 634
A N AGE
Sbjct: 16246 AKNVAGE 16252
Score = 34.7 bits (78), Expect = 0.86
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 18747 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18802
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 18803 RYNLTLENNSGSKTAFVNVRV 18823
Score = 34.7 bits (78), Expect = 0.86
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 19021 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 19079
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + +D Y NS G T +IV
Sbjct: 19080 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6274 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6331
Query: 1755 DDDAKYTCKAVNSLGE-ATCTAELIVE 1780
DD A Y N GE A LIVE
Sbjct: 6332 DDQANYNVSLTNHRGENVKSAANLIVE 6358
Score = 34.3 bits (77), Expect = 1.1
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 6987 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 7044
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 7045 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 7099
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 11837 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11896
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 11897 SDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1692 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1751
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17656 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17711
Query: 1752 VCGDDDA-KYTCKAVNSLG 1769
C +DA KY K NS G
Sbjct: 17712 NCDRNDAGKYILKLENSSG 17730
Score = 34.3 bits (77), Expect = 1.1
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 23750 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23807
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 23808 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23855
Score = 33.9 bits (76), Expect = 1.5
Identities = 51/246 (20%), Positives = 95/246 (38%), Gaps = 41/246 (16%)
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPE 507
L+D E Q+ V + + + + + W + I+ + + + +L + + + +
Sbjct: 2493 LRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKD 2551
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 567
D G YT A G+ S +TV A SKP L+D V +
Sbjct: 2552 DEGKYTFYA----GENMTSGKLTVAGG------------AISKP--------LTDQTVAE 2587
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
+ +V+ NP + WL +G + + + E G + L I +D G YT +
Sbjct: 2588 SQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYK 2646
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWL 686
S +T A L V+ I K +++T + Q + + + V W+
Sbjct: 2647 VATS----KTSAKLKVEAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWI 2695
Query: 687 RDGKAL 692
++G L
Sbjct: 2696 KNGVVL 2701
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10218
Query: 721 GQYEILLKNRVGE 733
G Y +L KN GE
Sbjct: 10219 GVYSLLAKNEAGE 10231
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 15104 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15162
Query: 1763 KAVNSLGEA 1771
A N G A
Sbjct: 15163 TATNPGGFA 15171
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 15469 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15526
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 15527 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15576
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 16580 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16637
Query: 623 TYTCEAWNSAG 633
YT NS+G
Sbjct: 16638 KYTLTLENSSG 16648
Score = 33.9 bits (76), Expect = 1.5
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+ + I + G P P + W++DG+ L K T V + L +K+ G+Y +
Sbjct: 17954 GEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 18012
Query: 726 LLKNRVGECSCQVSLML 742
N G + +S+++
Sbjct: 18013 TATNSAGTATENLSVIV 18029
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 21175 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21234
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 21235 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21279
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCL 515
G F + + G P P++TW L ++ T L ++D++ D G Y
Sbjct: 22290 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22349
Query: 516 AENALGQVSCSAWVTV 531
EN G + S V V
Sbjct: 22350 LENTAGVKTFSVTVVV 22365
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1676 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1725
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 23056 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 23110
Query: 1726 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 23111 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23157
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5204 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5261
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+V DD ++ + + E + TA+L V
Sbjct: 5262 EVTLDDISQIKAQ----VKELSSTAQLKV 5286
Score = 33.5 bits (75), Expect = 1.9
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5559 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5616
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCT 1774
D+ DD ++ +A+ EA T
Sbjct: 5617 DLSIDDTSQIRVEAMGMSSEAKLT 5640
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 7047 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 7106
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 7107 EIDVNVIARPSA 7118
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 8000 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 8051
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 8052 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 8106
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 513
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 11844 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11903
Query: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
A N G A V V +K ++ ++ V+ + T
Sbjct: 11904 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11942
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 13329 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13384
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 13385 NKYDAGKYILTLENSCGKKEYTIVVKV 13411
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 15101 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15159
Query: 104 YTCEATNGSG 113
YT ATN G
Sbjct: 15160 YTLTATNPGG 15169
Score = 33.5 bits (75), Expect = 1.9
Identities = 33/148 (22%), Positives = 53/148 (35%), Gaps = 5/148 (3%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 19427 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19485
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 19486 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19545
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKIT 185
K T + EG++ SCK+T
Sbjct: 19546 YIVEKRETSHLAWTICEGELQMTSCKVT 19573
Score = 33.5 bits (75), Expect = 1.9
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 19785 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19842
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 19843 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19899
Query: 121 LTV 123
+ V
Sbjct: 19900 VKV 19902
Score = 33.5 bits (75), Expect = 1.9
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 503
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19874
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTV 531
A D G YT +N L S + V V
Sbjct: 19875 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19902
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 19824 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19881
Query: 623 TYTCEAWN 630
YT N
Sbjct: 19882 KYTLTIQN 19889
Score = 33.1 bits (74), Expect = 2.5
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653
Query: 242 ASMSAE 247
A + E
Sbjct: 2654 AKLKVE 2659
Score = 33.1 bits (74), Expect = 2.5
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1656 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1701
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5244 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5303
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5304 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5360
Query: 1762 CKAVNSLGEATCTAE 1776
C +A T E
Sbjct: 5361 CDCGTDKTKANVTVE 5375
Score = 33.1 bits (74), Expect = 2.5
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1091
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 9036 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 9095
Query: 1092 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
+ ED+G Y A N G + V V D P+
Sbjct: 9096 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9127
Score = 33.1 bits (74), Expect = 2.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10854 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10910
Query: 1756 DDAKYTCKAVNSLGEATCTAELIV 1779
D Y+ N G T + +++V
Sbjct: 10911 DGGIYSLTVENPAGSKTVSVKVLV 10934
Score = 33.1 bits (74), Expect = 2.5
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 506
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19482
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 19483 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19524
Score = 33.1 bits (74), Expect = 2.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG 113
+G P P VTW ++ + + S R+ ++ + L I V D GKY NG G
Sbjct: 20924 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVG 20979
Score = 33.1 bits (74), Expect = 2.5
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 21997 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 22052
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 22053 KYTLTVENNSGSKSITFTVKV 22073
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 1755 DDDAKYTCKAVNSLGEAT 1772
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1094
G ++ + + P W +GK K K + L + + I +
Sbjct: 9453 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9512
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
G Y AKN AGQ +C+V V D P
Sbjct: 9513 HTGKYSITAKNKAGQKTANCRVKVMDVP 9540
Score = 32.7 bits (73), Expect = 3.3
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1761
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22690 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22747
Query: 1762 CKAVNSLG 1769
N+ G
Sbjct: 22748 LTVKNASG 22755
Score = 32.3 bits (72), Expect = 4.3
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1696 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1753
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6187 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6242
Query: 1754 GDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y V +G A A L V
Sbjct: 6243 LQDMGTY----VVMVGAARAAAHLTV 6264
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 545 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 10436 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10495
Query: 603 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 633
+ T +L ++++ + D+G Y NS G
Sbjct: 10496 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10526
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
I G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 13634 IKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13692
Query: 735 SCQVSL 740
+S+
Sbjct: 13693 EGTISI 13698
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 506
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 15096 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15154
Query: 507 EDHGTYTCLAENALG 521
D G YT A N G
Sbjct: 15155 RDSGAYTLTATNPGG 15169
Score = 32.3 bits (72), Expect = 4.3
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 515
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 20119 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20178
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 566
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 20179 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20225
Query: 567 DGSQVT 572
GSQVT
Sbjct: 20226 GGSQVT 20231
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20557
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
+ I++ ++G Y + N+ G A + VQ
Sbjct: 20558 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20589
Score = 32.3 bits (72), Expect = 4.3
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 23371 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23429
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 23430 TIRDTGEYTLELKNVTGTTSETIKVII 23456
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1691 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1625 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1677
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1750
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12294
Query: 1751 DVCGDDDAKYTCKAVNSLGE 1770
+ DD KY+ VN GE
Sbjct: 12295 NSTRDDSGKYSLTLVNPAGE 12314
Score = 32.0 bits (71), Expect = 5.6
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 717
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14467
Query: 718 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 750
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 14468 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14500
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18401
Query: 1755 DDDAKYTCKAVN 1766
D +Y K N
Sbjct: 18402 TDGGQYILKLSN 18413
Score = 32.0 bits (71), Expect = 5.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 22288 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22346
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 22347 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22398
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 22399 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22451
Score = 31.6 bits (70), Expect = 7.3
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13682
Query: 1762 CKAVNSLG--EATCTAELI 1778
N G E T + +++
Sbjct: 13683 ITLKNVAGTKEGTISIKVV 13701
Score = 31.6 bits (70), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAE--LHIQDALPEDHGTYTC 514
E +F L+ ++G P P ++W P+ R + E+ L + D D G YT
Sbjct: 13624 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13683
Query: 515 LAENALG 521
+N G
Sbjct: 13684 TLKNVAG 13690
Score = 31.6 bits (70), Expect = 7.3
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 625
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 18350 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18408
Query: 626 CEAWNSAG 633
+ N G
Sbjct: 18409 LKLSNVGG 18416
Score = 31.2 bits (69), Expect = 9.5
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 1664 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1710
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4330 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4389
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1769
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4390 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4446
Query: 1770 EATCTAELIV 1779
+ +A+L V
Sbjct: 4447 KTATSAKLTV 4456
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1007 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1066
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 6161 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6216
Query: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 6217 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6264
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALP 506
+L V G L +V G P P+ITW + Q R T E + + I D+
Sbjct: 7324 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 7383
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEK 534
D GTY A N G+ + V V +K
Sbjct: 7384 SDTGTYIIEAVNVCGRATAVVEVNVLDK 7411
Score = 31.2 bits (69), Expect = 9.5
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 10/79 (12%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLL-------NGQPIQYARSTCEAGVAE---LHIQDAL 505
V EG + + ++G P P +TW N +P+ Y + V + L I +
Sbjct: 9756 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9815
Query: 506 PEDHGTYTCLAENALGQVS 524
D G YT A N LG S
Sbjct: 9816 RSDTGLYTITAVNNLGTAS 9834
Score = 31.2 bits (69), Expect = 9.5
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14412 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14468
Query: 1756 DDAKYTCKAVNSLGE 1770
D K+ N G+
Sbjct: 14469 DTGKFVMTIENPAGK 14483
Score = 31.2 bits (69), Expect = 9.5
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 14414 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14465
Query: 617 FPEDTGTYTCEAWNSAGE 634
DTG + N AG+
Sbjct: 14466 NRYDTGKFVMTIENPAGK 14483
Score = 31.2 bits (69), Expect = 9.5
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1761
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14708 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14765
Query: 1762 CKAVNSLGE 1770
A N +GE
Sbjct: 14766 LTARNIVGE 14774
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 15098 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15156
Query: 720 AGQYEILLKNRVG 732
+G Y + N G
Sbjct: 15157 SGAYTLTATNPGG 15169
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19424 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19482
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y N G
Sbjct: 19483 RDTGQYVLTLKNVAG 19497
Score = 31.2 bits (69), Expect = 9.5
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 20114 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20173
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 20174 RYEITAANSSG 20184
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1761
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 22000 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 22055
Query: 1762 CKAVNSLGEATCT 1774
N+ G + T
Sbjct: 22056 LTVENNSGSKSIT 22068
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 514
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 23776 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23835
Query: 515 LAENALGQ 522
+ EN G+
Sbjct: 23836 VLENKCGK 23843
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 295 bits (755), Expect = 3e-79
Identities = 217/812 (26%), Positives = 353/812 (43%), Gaps = 130/812 (16%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCS 1085
AP FK++L++++V L C+V+ P + W GK + K+ I +G
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ I +D +Y+ A N G + + V+
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE-------------------------- 24523
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
P K +P + +R GE V + +G TW K
Sbjct: 24524 ---------------VPAKIHLPKTLEGMGAVHALR-GEVVSIKIPFSGKPDPVITWQKG 24567
Query: 1206 RKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
+ I + H +V + + + L ++ G Y + +N+ G Q V L V D PDP
Sbjct: 24568 QDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDP 24627
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQD 1324
P G SD+ S+ L+W + DGGS + +Y +E + + W + R T + V +
Sbjct: 24628 PRGVK-VSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTVIN 24686
Query: 1325 LLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVT 1384
L Y+FRV A N +G S+PS+ SE T E + E D+ EV +
Sbjct: 24687 LFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETR---EVSMTKAS 24743
Query: 1385 INTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIM 1444
++ +++ + Y I E LG G+FG V R VE ++K + KF K ++ +++EISI+
Sbjct: 24744 HSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKV-KGTDQVLVKKEISIL 24802
Query: 1445 NCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGV 1504
N H ++ ++FE +VM+ E +SG ++FERI FEL ERE + Y+ Q+ E +
Sbjct: 24803 NIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVHQVCEAL 24862
Query: 1505 EYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVI 1564
+++H I H D++PENI+ + + IK+I+FG AR+L+ + ++LF PE+ APEV
Sbjct: 24863 QFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEYYAPEVH 24922
Query: 1565 NYEPIGYATDMWSIGVICYIL--------------------------------------- 1585
++ + ATDMWS+G + Y+L
Sbjct: 24923 QHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKEISIEAM 24982
Query: 1586 ------------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVR 1633
+R+ ++ LQHPWL + + + K + + ++Y +K N V
Sbjct: 24983 DFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYY-HTLIKKDLNMVV 25041
Query: 1634 AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1693
+ R+S I +S G + + +E VS + AV EE HVK
Sbjct: 25042 SAARISCGGAI------RSQKGVSVAKVKVASIEI-GPVSGQIMHAVGEEGGHVK----- 25089
Query: 1694 TIRDLEVVEGSAARFDCKIEGY-PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
+ CKIE Y +V W+ + + S ++I Y EDG L + D+
Sbjct: 25090 --------------YVCKIENYDQSTQVTWYFGVRQLENSEKYEITY-EDGVAILYVKDI 25134
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
DD Y CK VN GE + AEL V+ + E
Sbjct: 25135 TKLDDGTYRCKVVNDYGEDSSYAELFVKGVRE 25166
Score = 166 bits (420), Expect = 2e-40
Identities = 161/707 (22%), Positives = 277/707 (39%), Gaps = 57/707 (8%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELT 122
+VTW+++G+ + G F GT+ L I+ + E D+G+Y CE + G + ++
Sbjct: 26251 EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFM 26310
Query: 123 VEG-----------SFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVV 171
+ S K+ Q T+ + A E S P T L
Sbjct: 26311 GQAFKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPISS-----KPVIVTGLQDTT 26365
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V + +F+ K TG P+P W K + + +SE G LEIH + D G+Y
Sbjct: 26366 VSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26425
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
TC V N +G S S +L+I+ + V K S++ + V+ +E + A
Sbjct: 26426 TCTVKNSAGSVSSSCKLTIKAIKDTEAQKVSTQK--TSEITPQKKAVVQEEIS----QKA 26479
Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK--TSSSITLQA 349
+S+ + A + S E K S T+ + ++ + T +S +
Sbjct: 26480 LRSEEIKMSEAKSQEKLALKEEASKVLIS--EEVKKSAATSLEKSIVHEEITKTSQASEE 26537
Query: 350 ARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT---FPTRQPGLGSQD-----VVSKAANR 401
R E +A + G+ A AT + L + + V
Sbjct: 26538 VRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTL 26597
Query: 402 RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQD 461
I RD SK + VK + E + AP+F S + + EGQ+
Sbjct: 26598 TIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKE----LSDAPAFISQPRSQNINEGQN 26653
Query: 462 FVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCLAEN 518
+ C + G P P I W N PI + + V L I++A D G YT A+N
Sbjct: 26654 VLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKN 26713
Query: 519 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
GQ S +A S +LP+ +P+ + L+ D + GS + +VQ+S
Sbjct: 26714 FRGQCSATA------------SLMVLPLV-EEPSREVVLRTSGDTS-LQGSFSSQSVQMS 26759
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 638
+ + + + F Q +QE F E + + N ++ +
Sbjct: 26760 ASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT-QLESS 26818
Query: 639 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTG 697
++ G P + P ++ G+ + ++CA G+P P V W G+ + ++ G
Sbjct: 26819 TSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQG 26878
Query: 698 HFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN 744
F + +D+ TL++ VQ G Y + L N G S V++ +++
Sbjct: 26879 RFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRS 26925
Score = 143 bits (360), Expect = 2e-33
Identities = 199/848 (23%), Positives = 326/848 (38%), Gaps = 170/848 (20%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHE 98
+N+ + E TA FE V + P + W +NG I +F + ++G L+I
Sbjct: 2843 KNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIV--VQGKLHQLIIMNTST 2899
Query: 99 EDRGKYTCEATNGSGARQVTV----------------------ELTV--EGSFAKQLGQP 134
ED +YT N + +TV E+TV EG K L
Sbjct: 2900 EDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYKWLKNG 2959
Query: 135 VVSKT---------------------LGDR----FSAPAVETRPSIWGECPP-KFATKLG 168
V K+ GD F A + +++ E +F +
Sbjct: 2960 VEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIK 3019
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
+ V E + F C+++ P V W+K + LQ + R+ + ++ + L I D
Sbjct: 3020 DIKVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDA 3078
Query: 229 GVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSL 288
G YT + +G +A+L ++G D RS ++KEV VI K+ +
Sbjct: 3079 GKYTVV----AGGNVSTAKLFVEGRDVRIRS-----------IKKEV-QVIEKQRAVVEF 3122
Query: 289 EAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPR----TAPQTPVLQKTSSS 344
E + + G + + + E ++ S T V + SS
Sbjct: 3123 EVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSS 3182
Query: 345 ITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLG---SQDVVSKAANR 401
+TL +P P+ L L P + +PA QP + + ++S
Sbjct: 3183 VTLYVNAPEP-PQV--LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKC 3239
Query: 402 RIPMEGQRDS-----AFPKFESKPQSQEVKENQTVKFRCEGLAVM--EVA---------- 444
+ +GQ + AFP+ ++ + E K + V L+V EV
Sbjct: 3240 KFLHDGQEYTLLLIEAFPE-DAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP 3298
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHI 501
P+ + L+D EGQ QC V GT + +++W + P ++ R T +L I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS------------------------- 536
+A PED GTYT +A NA+GQVS +A +++ +S
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAE 3417
Query: 537 -----------SRKSEYL-----LPVAPSK------PTAPIFLQGLSDLKVMDGSQVTMT 574
S+ +E L PV P+K T PIF++ +S+ + G T++
Sbjct: 3418 EEGLHSAELQLSKINETLELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLS 3477
Query: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
V V G P P++ W NG + S D+ F G HSL I ED G YTC A N G+
Sbjct: 3478 VTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3537
Query: 635 VRTQAVLTVQ---EPHDGTQ-----------------PWFISKPRSVTASLGQSVLISCA 674
A L + E H T+ P F+ + + + + G +
Sbjct: 3538 TICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYT 3597
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
+ G+P PTV W ++ K LC + + T ++ Q +G Y +N +GE
Sbjct: 3598 VVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGES 3657
Query: 735 SCQVSLML 742
+C L++
Sbjct: 3658 TCAAELLV 3665
Score = 122 bits (306), Expect = 3e-27
Identities = 158/734 (21%), Positives = 285/734 (38%), Gaps = 96/734 (13%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G + ++ I G PFP W ++G+ + K + +E LV+K+ +G Y++
Sbjct: 23654 GGVIRLTIPIKGKPFPICKWTKEGQDISK---RAMIATSETHTELVIKEADRGDSGTYDL 23710
Query: 726 LLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGV------GADGGGSDRYGS 779
+L+N+ G+ + + + + S P G P +D+ V AD GG+D G
Sbjct: 23711 VLENKCGKKAVYIKVRVIGSPNS--PEG--PLEYDDIQVRSVRVSWRPPADDGGADILGY 23766
Query: 780 LRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKK--VS 837
+ W + VRG +++ E R Q L + V+
Sbjct: 23767 ILERREVPKAAWYTID--SRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVT 23824
Query: 838 TKT-LSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT--S 894
KT L+ + P E +D + + + +V + ++ + K +
Sbjct: 23825 PKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRV-TGYYIERKETSTDKWVRHN 23883
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNA-KAVESSKPLSNAQPSGP 953
KT + + PD + ++ A+N +ET A + V P G
Sbjct: 23884 KTQITTTMYTVTGLVPDAEY----QFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGE 23939
Query: 954 LKPVGNAKPAETL---KP-MGNAKPAETLKPMGNAKPDENLKSASKEELKKD-------- 1001
L+ + +K + TL KP K D K ++KE +K
Sbjct: 23940 LEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLL 23999
Query: 1002 ----------VKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQ 1051
+N+ R T + K + G AP +++++DV G+ L CQ
Sbjct: 24000 EATEYEFRVFAENETGLSRPRR-TAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQ 24058
Query: 1052 VSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAE 1111
+ P I W GK L ++ +S +G ++++ ED G+Y C+A N+ G+ E
Sbjct: 24059 IVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVE 24118
Query: 1112 CSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQI 1171
S ++ + P P P K
Sbjct: 24119 TSSKLLLQATPQFH---------------------------------PGYPLK------- 24138
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL-A 1230
E G ++ L G TW +K +Q SE++ +EN+E+ + L +
Sbjct: 24139 ----EKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNV 24194
Query: 1231 ARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
R+ H G Y + + N G+ A +++ + DKPD P G + +S +SW + DG
Sbjct: 24195 QRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24254
Query: 1291 GSAVQSYSIEIWDS-ANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GS + +Y +E ++ W+ +++ S T+ + +L + Y FRV A N +G S+P +
Sbjct: 24255 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24314
Query: 1349 ESELTTVGEKPEEP 1362
S + + E+P
Sbjct: 24315 VSSVVIIKSPFEKP 24328
Score = 118 bits (295), Expect = 6e-26
Identities = 175/807 (21%), Positives = 305/807 (37%), Gaps = 149/807 (18%)
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
T P + GL ++ V++G VT+ +SG P P V W +I+ S DF + L
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE-------------------------- 645
I+E F ED+G +TC A N AG V T L VQ
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 646 ---------------PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
P + P+FI+KP G SV+ C + G+P P V+W + G
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1074
Query: 691 ALCKDTGH-FEVLQNEDV--FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
L TG+ ++V N+ LV+ AG+Y I+++N+ GE S SL L+ +
Sbjct: 1075 PL--TTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL-LEEADY 1131
Query: 748 RALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWP-ARGQGWLEEEDGEDVRGVLKR 806
L + ++ + V + G PG+ + + E+E + + K
Sbjct: 1132 ELLMKSQQEMLYQTQVTAFV-----QEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKD 1186
Query: 807 RVETRQHTEEAIRQQEVEQLDFRDLLGKKVS---TKTLSEDDLKEIPAEQMDFRANLQRQ 863
V R + E+ QE F + L K++ KT E+ L+E E+M +
Sbjct: 1187 TVVVRTYVED----QEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEA 1242
Query: 864 VKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVP--------EKVPPPKPATPDF--- 912
V+ S + ++ + + ++ V S P+P +++ + DF
Sbjct: 1243 VE----SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQD 1298
Query: 913 -RSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSG-----PLKPVGNAKPAETL 966
R+ L LP + G +A N K NA SG P P+G TL
Sbjct: 1299 GRASLRIPVVLPEDEGIYTAFASNIK--------GNAICSGKLYVEPAAPLGAPTYIPTL 1350
Query: 967 KPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG 1026
+P+ + +L P ++ + A + + + S+ +
Sbjct: 1351 EPVSRIR---SLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLER 1407
Query: 1027 T-APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSL 1083
P F K EG+ +V P W +G+ + T +++ ++G+
Sbjct: 1408 LYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ 1467
Query: 1084 CSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP 1143
S+ I A P D G + VA+N AG++ S +TV+
Sbjct: 1468 -SLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV---------------------- 1504
Query: 1144 VLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1203
+ + P ++ ++ ++ G +E+ + TG W+
Sbjct: 1505 --------------------EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWL 1544
Query: 1204 KFRKQIQESEH--MKVENSENGSKLTILAARQEHCGCYTLLVENKLG--SRQAQVNLTV- 1258
K I ++ +++E ++ + L I + + YT NK G + + +VN+ V
Sbjct: 1545 KNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVE 1604
Query: 1259 VDKPDP------PAGTPCASDIRSSSL 1279
+P+P P GT A +I + L
Sbjct: 1605 FAEPEPERKLIIPRGTYRAKEIAAPEL 1631
Score = 113 bits (282), Expect = 2e-24
Identities = 211/1044 (20%), Positives = 358/1044 (34%), Gaps = 249/1044 (23%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
+K S RK E L + AP + +V G + V P EV W HNG
Sbjct: 25856 QKTSERKYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGV 25915
Query: 593 EIQESE----------------DFHFEQRGTQHSLCI----------------------- 613
E+QES D H + GT ++C
Sbjct: 25916 ELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYA 25975
Query: 614 ---------QEVFPEDTGTYT-----------CEAWNSAGEVRTQAVLTVQE----PHDG 649
+ VFPE T T EA +S EV++Q T + H
Sbjct: 25976 SQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSA 26035
Query: 650 TQPW--------------------------FISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ ++KPRS+T G+S SC G+P PTV
Sbjct: 26036 SAEMKSAALEEKSLEEKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTV 26095
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
WLR G+ L H +V + T + VQ G Y ++++N G+ + +L +Q
Sbjct: 26096 TWLRKGQVLSTSARH-QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Query: 744 NS------------------------SARALPRGREPASCEDLCGGGVGADGGGSDRYGS 779
+ + ++ R + P +++
Sbjct: 26155 KARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQH 26214
Query: 780 LRPGWPARGQGWLEEEDGEDVR--------GVLKRRVETRQHTEEAIRQQEVEQLDFRDL 831
L P + +L+ E +++ VL+ + T + +++ Q +
Sbjct: 26215 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274
Query: 832 LGKKVSTKTLSEDD----LKEIPAEQMDFRANLQRQVKP-KTVSEEERKVHSPQQVDFR- 885
++ L+E D + EI E + NLQ + K++ E+ K+ ++ D +
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334
Query: 886 --SVLAKKGTSKTPVPEKVPP--------------------------PKPA---TPDFRS 914
S + +K K P P P P+P T D ++
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKA 26394
Query: 915 VL-GGKKKLPAENGS---------------------------SSAETLNAKAVESSKPLS 946
+ GGK KL + G SS+ L KA++ ++
Sbjct: 26395 ITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQK 26454
Query: 947 -NAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENL---KSASK----EEL 998
+ Q + + P A E + A +E +K M AK E L + ASK EE+
Sbjct: 26455 VSTQKTSEITPQKKAVVQEEISQ--KALRSEEIK-MSEAKSQEKLALKEEASKVLISEEV 26511
Query: 999 KKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
KK + H T + SE T K + + EG++L+L+ ++
Sbjct: 26512 KKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAG--AT 26569
Query: 1059 TIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ W LNG L ++ GS +++I++A D G+ C++K G +C +T+
Sbjct: 26570 DVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629
Query: 1119 DDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQ 1178
+ E+ SDA P I P Q
Sbjct: 26630 ----------SKEL----------------SDA-----------------PAFISQPRSQ 26646
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
+ G++V +++G W K I S ++ + S N L I A G
Sbjct: 26647 NINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGK 26706
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ +N G A +L V+ + P+ +SL S+ S ++ Q S
Sbjct: 26707 YTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEAS 26766
Query: 1299 IEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ----ESELTT 1354
+ S++ + + + S + Q + E + + + G S +Q S++
Sbjct: 26767 FSSFSSSSAS--SMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLESSTSKMLK 26824
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEV 1378
G + PK E SD E +V
Sbjct: 26825 AGIRGIPPKIEALPSDISIDEGKV 26848
Score = 111 bits (278), Expect = 6e-24
Identities = 67/201 (33%), Positives = 103/201 (51%), Gaps = 4/201 (1%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+PP+I+ PE ++AG+ + + V G TC W K ++ S H+ V +++ S L
Sbjct: 12401 LPPKILM-PEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL 12459
Query: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGS 1286
I ++ G Y+L EN G+ ++ + V+D P PP SDI + + +LSW+
Sbjct: 12460 IIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIP 12519
Query: 1287 SYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
DGGS + +Y +E D + W LA+ TS V L+P EY FRVRA N +G SE
Sbjct: 12520 LEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE 12579
Query: 1346 PSQESELTTVGE--KPEEPKD 1364
P ++ P EPK+
Sbjct: 12580 PLTSPKMVAQFPFGVPSEPKN 12600
Score = 110 bits (276), Expect = 9e-24
Identities = 154/692 (22%), Positives = 268/692 (38%), Gaps = 99/692 (14%)
Query: 63 QVTWHRNGQPITSGGRF--LLDCGIRGTFSLVIHAVHEED-RGKYTCEATNGSGARQVTV 119
+V W+ + + S +F L D + T++LVI V+ ED +G+Y CEA N SG +
Sbjct: 4271 EVNWYFENKLVPSDEKFKCLQD---QNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4327
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
+LTV A PV+ + K+ + V G + +
Sbjct: 4328 KLTVVKRAA-----PVIKR---------------------------KIEPLEVALGHLAK 4355
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F+C+I P + W K + S + S+ + LEI D G YTC N
Sbjct: 4356 FTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEY 4415
Query: 240 GKASMSAEL--SIQGLDSANRSFVRETKATNSDVRKEVT--NVISKESKLDSLEAAAKS- 294
G S +A L ++ G + R + E K + ++EV +V+ K + + + K
Sbjct: 4416 GSVSCTATLTVTVPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEEEEPKVEPKKL 4472
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
+ P PP P+P E ++ + R P+ + + +I L A +P
Sbjct: 4473 EKVKKPAVPEPPP------PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 4526
Query: 355 EPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFP 414
+P A + P E P P T P ++ +AA + P++G
Sbjct: 4527 KPEAEVKTIKPPPVEPEPTPI-AAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 4585
Query: 415 KFES-----KPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIE----GQDFVLQ 465
E+ +P S K F + + V F +KD + E G + +
Sbjct: 4586 PIEAERRKLRPGSGGEKPPDEAPFTYQ---LKAVPLKFVKEIKDIILTESEFVGSSAIFE 4642
Query: 466 CSVRGTPVPRI-TWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALG 521
C V +P I TW+ +G I+ + R + +LHI D D G YTC+
Sbjct: 4643 CLV--SPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNK 4700
Query: 522 QVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL-SDLKVMDGSQVTMTVQVSGN 580
+ + +A + V E LPV F++ L ++ V+ G + ++ ++ N
Sbjct: 4701 EKTSTAKLVVEE----------LPVR--------FVKTLEEEVTVVKGQPLYLSCEL--N 4740
Query: 581 PPPEVIWLHNGNEIQESEDFHFE-QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 639
+V+W +G + E G +L I + D GTYT N+ +
Sbjct: 4741 KERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSC 4800
Query: 640 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL-CKDTGH 698
V V+ D W + R + + +C IA D P + W + + +
Sbjct: 4801 VKVVEVIRD----WLVKPIRDQHVKPKGTAIFACDIAKDT-PNIKWFKGYDEIPAEPNDK 4855
Query: 699 FEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
E+L++ + L +K P +Y + ++ +
Sbjct: 4856 TEILRDGNHLYLKIKNAMPEDIAEYAVEIEGK 4887
Score = 110 bits (275), Expect = 1e-23
Identities = 73/206 (35%), Positives = 104/206 (50%), Gaps = 21/206 (10%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAE 498
AP+F+ L+ V+EG + + G PVP ++W +GQ I + + + G A+
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I + G Y+ A N GQ + +A + V K+E AP P F+Q
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLV-------KAE----TAP-----PNFVQ 108
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
L + V GSQV + V+V+G P P V + +G EIQ S DF Q G +SL I E +P
Sbjct: 109 RLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYP 168
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQ 644
ED+GTY+ A NS G + A L VQ
Sbjct: 169 EDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 109 bits (272), Expect = 3e-23
Identities = 83/306 (27%), Positives = 137/306 (44%), Gaps = 57/306 (18%)
Query: 30 TEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF 89
T+AP F P +++ + EG+TA FE + G+P P+V+W R+GQ I++ G++ +F
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTL----PGVQISF 58
Query: 90 S-----LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRF 144
S L I AV + + G+Y+ +ATNGSG T EL V+ A
Sbjct: 59 SDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------- 102
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PP F +L + V++G R ++TG P P V + + +Q S
Sbjct: 103 ---------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSS 147
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG------------ 252
+S++ + L I +D G Y+ N G+A+ +AEL +QG
Sbjct: 148 LDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTI 207
Query: 253 LDSANRSFVRETKATNS-DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ +A S R+T+ + + ++ + E +D AA + +P R PP +
Sbjct: 208 VSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDG--AAGQQLPHKTPPR--IPPKPKS 263
Query: 312 SQPQPP 317
P PP
Sbjct: 264 RSPTPP 269
Score = 109 bits (272), Expect = 3e-23
Identities = 65/193 (33%), Positives = 101/193 (52%), Gaps = 3/193 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +EL VTG TW K +++ + + +EN S +TI+ +++ G Y
Sbjct: 7205 VKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTY 7264
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ N G A V + V+DKP PPA +D+ + S L+W DGGS + +Y +
Sbjct: 7265 IIEAVNVCGRATAVVEVNVLDKPGPPAAFD-ITDVTNESCLLTWNPPRDDGGSKITNYVV 7323
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE- 1357
E + ++ W +L +T + T+F L+P+ EY FRV A N+YG EP Q S +T +
Sbjct: 7324 ERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQF 7383
Query: 1358 KPEEPKDEVEVSD 1370
P P +E SD
Sbjct: 7384 DPPGPPTRLEPSD 7396
Score = 107 bits (266), Expect = 1e-22
Identities = 159/700 (22%), Positives = 240/700 (34%), Gaps = 154/700 (22%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
+N I EG F ++ GYP P++ W+++G+ I G R+ +D G SL I V E
Sbjct: 1252 KNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPE 1311
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD----RFSAPAVETRPSI 155
D G YT A+N G + +L VE A LG P TL R +P +R I
Sbjct: 1312 DEGIYTAFASNIKGNAICSGKLYVEP--AAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPI 1369
Query: 156 WGE------------------------------------CPPKFATKLGRVVVKEGQMGR 179
P F K EGQ R
Sbjct: 1370 RMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTAR 1429
Query: 180 FSCKITGRPQPQVTWL-KGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
F K+ GRP P+ W G + V +++G Q L I D G +T + N
Sbjct: 1430 FDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNR 1489
Query: 239 SGKASMSAELSIQGLD-SANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNC 297
+G++S+S L+++ ++ FV + K N I + S+L+ A + N
Sbjct: 1490 AGRSSISVILTVEAVEHQVKPMFVEKLKNVN----------IKEGSRLEMKVRATGNPN- 1538
Query: 298 SSPQRGGSPPWAANSQ---PQPPRESKLESCKDSPRTAPQTPVLQ--------------- 339
W NS P + ++E K + V Q
Sbjct: 1539 ------PDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGR 1592
Query: 340 -KTSSSITLQAARVQPEPRAPGLGVLSPSGEER-KRPAPP--RPATFPTRQPGLGSQDVV 395
T + ++ +PEP ++ P G R K A P P Q D+
Sbjct: 1593 DTTRCKVNVEVEFAEPEPERK---LIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLY 1649
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
K ++ P F+ K S +K F C +
Sbjct: 1650 DKEKQQK-----------PFFKKKLTSLRLKRFGPAHFECRLTPI--------------- 1683
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTY 512
G P + WL +G+P++ A R E G L A D G
Sbjct: 1684 --------------GDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGII 1729
Query: 513 TCLAENALGQVSCSAWVTVHEKKSSRKSEYL------------------------LPVAP 548
TC A N G SA + V ++KS + L +
Sbjct: 1730 TCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQ 1789
Query: 549 SKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 608
+ P + ++V++G +V+G P P+V W NG I++S+ F G
Sbjct: 1790 KEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGI- 1848
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
H L I + DTG A N G + + L +Q+ D
Sbjct: 1849 HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQRED 1888
Score = 102 bits (253), Expect = 4e-21
Identities = 57/185 (30%), Positives = 97/185 (52%), Gaps = 7/185 (3%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
+++ E K RAG SV+L ++G T W K K++Q + + VEN+ + + + I A
Sbjct: 20379 LEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDA 20438
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ + GCY L + N +GS A + + ++DKP PP G + + +TL W + DGG
Sbjct: 20439 DRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGG 20498
Query: 1292 SAVQSYSIEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+ + Y +E +++ W + L C T+ + + +EY FRVRA+N YG EP
Sbjct: 20499 AKITHYIVEKRETSRVVWSMVSEHLEECIITTTKI---IKGNEYIFRVRAVNKYGIGEPL 20555
Query: 1348 QESEL 1352
+ +
Sbjct: 20556 ESDSV 20560
Score = 101 bits (252), Expect = 6e-21
Identities = 76/249 (30%), Positives = 112/249 (44%), Gaps = 8/249 (3%)
Query: 1167 MPPQI---IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG 1223
+PP + ++ E V+AG +V + G T W +I+ EH VE
Sbjct: 11009 VPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFS 11068
Query: 1224 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1283
S LTI + G Y + V N GS+ V+LTV+D P PP G D+ +T+SW
Sbjct: 11069 SVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISW 11128
Query: 1284 YGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVRAINVYG 1342
DGGS V +Y +E D+ TW +++ S T + L EY FRVRA N G
Sbjct: 11129 QPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIG 11188
Query: 1343 TSEPSQESELTTVGEK--PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEER 1400
P +S T K P P + V+D E V + + ++ +Y +E R
Sbjct: 11189 VG-PPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYY-MERR 11246
Query: 1401 LGSGKFGQV 1409
+GK+ +V
Sbjct: 11247 EVTGKWVRV 11255
Score = 101 bits (252), Expect = 6e-21
Identities = 58/205 (28%), Positives = 104/205 (50%), Gaps = 6/205 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ +M P+ + + V AGES ++ + G T W+K +++ + +++++++
Sbjct: 16043 PPRISMDPK---YKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTD 16099
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L++ A + G Y L +N G R VN+ V+D+P PP G S + + TL
Sbjct: 16100 FATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTL 16159
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGGS + +Y +E +++ W + A ++ S V LL +EY FR+ A+N
Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNK 16219
Query: 1341 YGTSEPSQESELTTVGE--KPEEPK 1363
YG EP + + P+ PK
Sbjct: 16220 YGVGEPLESEPVVAKNPFVVPDAPK 16244
Score = 101 bits (251), Expect = 7e-21
Identities = 78/253 (30%), Positives = 112/253 (44%), Gaps = 15/253 (5%)
Query: 1174 FPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQ 1233
F + VRAG S+ LF G T W K + S + +++ S LT+ +
Sbjct: 21866 FKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNR 21923
Query: 1234 EHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSA 1293
G YTL VEN GS+ + V+D P PP G D+ S TL W DGG+
Sbjct: 21924 NDAGKYTLTVENNSGSKSITFTVKVLDTPGPP-GPITFKDVTRGSATLMWDAPLLDGGAR 21982
Query: 1294 VQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL 1352
+ Y +E +++ ++W+ ++ C F V DL Y FRV A+N YG EP + E
Sbjct: 21983 IHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEP 22042
Query: 1353 TTVGEKPEEPK--DEVEVSDDDE----KEPEVD----YRTVTINTEQKVSDFYDIEERLG 1402
E+P P+ D V+ S +P+ D + QK SDF+ +E
Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFW-VEAGHT 22101
Query: 1403 SGKFGQVFRLVEK 1415
V RLVEK
Sbjct: 22102 KQLTFTVERLVEK 22114
Score = 100 bits (250), Expect = 1e-20
Identities = 71/255 (27%), Positives = 119/255 (46%), Gaps = 20/255 (7%)
Query: 1172 IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAA 1231
++F + ++AGE+ L V+G P T W K K+++ + ++++ ++ + L +
Sbjct: 14968 VKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDS 15027
Query: 1232 RQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGG 1291
+ G YTL N G + N+ V+D+P PP G +++ S LSW+ DGG
Sbjct: 15028 TRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGG 15087
Query: 1292 SAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
+ + Y ++ +++ W +A+ + T V LL +EY FRV A+N YG EP +
Sbjct: 15088 AKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESE 15147
Query: 1351 ELTTVGE--KPEEPKD-EVEVSDDDEK-----EPEVDYRTVTINTEQKVSDFYDIEERLG 1402
+ V P+ PK+ EV D P+ D + IN Y +E R
Sbjct: 15148 PVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIIN--------YIVERR-- 15197
Query: 1403 SGKFGQVFRLVEKKT 1417
K GQ + KKT
Sbjct: 15198 -DKAGQRWIKCNKKT 15211
Score = 100 bits (249), Expect = 1e-20
Identities = 57/166 (34%), Positives = 88/166 (53%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V AGE +++ G TW K ++++ + E++EN S LTI A +E G Y
Sbjct: 15662 VLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHY 15721
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ + N G +N+ V+DKP PP G ++ + S+TLSW YDGGS++ +Y +
Sbjct: 15722 VVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 15781
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
E D++ TW+ + AT T+ L EY+FR+ A N YG S
Sbjct: 15782 EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15827
Score = 100 bits (248), Expect = 2e-20
Identities = 76/305 (24%), Positives = 116/305 (38%), Gaps = 60/305 (19%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAE 498
V F S +K+ ++EG C + G P+P+I W +G+ I +Y + G A
Sbjct: 1243 VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRAS 1302
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY---LLPVAPSKPTAP- 554
L I LPED G YT A N G CS + V Y L PV+ + +P
Sbjct: 1303 LRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPR 1362
Query: 555 -------------------------------------------------IFLQGLSDLKV 565
+F+ K
Sbjct: 1363 SVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEI--QESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
++G ++V G P PE W H+G +I + ++ GTQ SL I P D+G
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQ-SLIIVPATPSDSGE 1481
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+T A N AG +LTV+ +P F+ K ++V G + + G+P P +
Sbjct: 1482 WTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDI 1541
Query: 684 HWLRD 688
WL++
Sbjct: 1542 VWLKN 1546
Score = 100 bits (248), Expect = 2e-20
Identities = 66/237 (27%), Positives = 109/237 (45%), Gaps = 19/237 (8%)
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF-------RKQIQESEHMKVEN 1219
MPP I E +V G +V + K+ G T TW K ++ + H+
Sbjct: 9619 MPPSI-DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLV 9677
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSL 1279
++ L I +R+ G YT+ N LG+ ++ L V+ +P PP G + + +
Sbjct: 9678 VDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQM 9737
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAI 1338
TLSW+ DGGS + +Y IE ++ KTW +++ + ++ + LL HEY FR+ A
Sbjct: 9738 TLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQ 9797
Query: 1339 NVYGTSEPSQESELTTVGEKPEEPKD--EVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
N YG EP + +PE ++ V + D V ++T+N E+ D
Sbjct: 9798 NKYGIGEP--------LDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYD 9846
Score = 99.4 bits (246), Expect = 3e-20
Identities = 59/189 (31%), Positives = 97/189 (51%), Gaps = 4/189 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P+ +M P+ F + V AGE+ L V G T W++ K+I+ES +++N++
Sbjct: 17126 PRISMDPK---FRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDF 17182
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLS 1282
+ L + A + G Y L N GS+ VN+ V+D+P PP G + + S +L+
Sbjct: 17183 KALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLT 17242
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVY 1341
W DGGS + Y +E +++ W +A+ + S V LL +EY FR+ A+N Y
Sbjct: 17243 WSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKY 17302
Query: 1342 GTSEPSQES 1350
G EP + +
Sbjct: 17303 GVGEPLESA 17311
Score = 99.0 bits (245), Expect = 4e-20
Identities = 98/385 (25%), Positives = 150/385 (38%), Gaps = 54/385 (14%)
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
R SP + + P E E+ A L TSS A ++ +AP
Sbjct: 764 RTASPHFTVSKISVPKTEHGYEASIAGSAIATLQKELSATSS-----AQKITKSVKAP-- 816
Query: 362 GVLSPSGEERKRPAPPRPATFP------TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPK 415
+ PS E R R P FP T + G + V K I R+ F
Sbjct: 817 -TVKPS-ETRVRAEPTPLPQFPFADTPDTYKSEAGVE--VKKEVGVSITGTTVREERFEV 872
Query: 416 FESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 475
+ E K +T + + + P+ S LK+ VIEG+ L+C + G P P
Sbjct: 873 LHGR----EAKVTETARVPAP-VEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPT 927
Query: 476 ITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
+TW I+ + + T ++G+A L I++A ED G +TC A N G VS S ++ V
Sbjct: 928 VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 987
Query: 533 -----EKKSSRKSEYLLP----------------------VAPSKPTAPIFLQGLSDLKV 565
EK+++ +E P +P AP F+ K+
Sbjct: 988 VSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKL 1047
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF--HFEQRGTQHSLCIQEVFPEDTGT 623
++G V QV GNP P V W +G + + + ++ + L I F +D G
Sbjct: 1048 VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGE 1107
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHD 648
YT N GE A L + ++
Sbjct: 1108 YTIVVRNKHGETSASASLLEEADYE 1132
Score = 97.4 bits (241), Expect = 1e-19
Identities = 55/168 (32%), Positives = 92/168 (54%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G +V L G + +W+K ++ESE ++ +EN L+I A++EH G Y
Sbjct: 21078 VRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKY 21137
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T++++N + + + + P P G +I++ S+ LSW +GG + YSI
Sbjct: 21138 TVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 21197
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E +++ WK + ++ T+F V +L+ D EY+FRVRA N YG S+P
Sbjct: 21198 EKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQP 21245
Score = 96.7 bits (239), Expect = 2e-19
Identities = 56/168 (33%), Positives = 89/168 (52%), Gaps = 2/168 (1%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG +V L V G T +W K ++ +E +K+ N L + + ++ G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN GS+ A + L V+DKP PPA + + S LSW DGGS + +Y +
Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVK-INKMYSDRAMLSWEPPLEDGGSEITNYIV 12928
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
+ +++ W ++ AT TS +V+ L+ HEY+FR+ A N YG +P
Sbjct: 12929 DKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP 12976
Score = 96.3 bits (238), Expect = 2e-19
Identities = 57/211 (27%), Positives = 97/211 (45%), Gaps = 7/211 (3%)
Query: 1159 PKTPPKAAMPPQI-IQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P T PP + + F + +R GE+ L G+ +G +W K + E + +
Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSS 1277
+ + L + A++ G Y ++VEN GSR+ + VVD+P PP G ++
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQDLLPDHEYKFRVR 1336
+ +SW DGGS + +Y IE + W + + + T+ V LL +Y FR+
Sbjct: 10431 YMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIH 10490
Query: 1337 AINVYGTSEPSQESELTT-----VGEKPEEP 1362
A N+YG S+P + V + P++P
Sbjct: 10491 AENLYGISDPLVSDSMKAKDRFRVPDAPDQP 10521
Score = 95.9 bits (237), Expect = 3e-19
Identities = 158/697 (22%), Positives = 252/697 (36%), Gaps = 128/697 (18%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P +++ P EAP ++ + +G+ A F RV G P+P+ W++NG I R
Sbjct: 2020 PDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIY 2079
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
LVI V ED +A N +G L V+ AKQL
Sbjct: 2080 WYWPEDNVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQ---AKQL--------- 2127
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ-MGRFSCKITGRPQPQVTWLKGNV 199
F +L VV KE M F C+ T P +V W K +
Sbjct: 2128 --------------------ITFTQELQDVVAKEKDTMATFECE-TSEPFVKVKWYKDGM 2166
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
+ + + + L I ++ D Y+C++V +A+L ++G A
Sbjct: 2167 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVEDEN-VKTTAKLIVEG---AVVE 2222
Query: 260 FVRETKATN--SDVRKEVTNVISKES-----KLDSLEAAAKSKNCSSPQRGGSPPWAANS 312
FV+E + E+ ++S E+ + +E + K + +RG +
Sbjct: 2223 FVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDV 2282
Query: 313 QPQPPRE------SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAP---GLGV 363
+ E K +CK + P +LQ S + VQ E + GV
Sbjct: 2283 TKEDQGEYSFVIDGKKTTCKLKMKPRP-IAILQGLSDQKVCEGDIVQLEVKVSLESVEGV 2341
Query: 364 LSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQ 423
G+E QP V+ K ++ + + ++ A
Sbjct: 2342 WMKDGQEV--------------QPSDRVHIVIDKQSHMLLIEDMTKEDA----------- 2376
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFS----SVLKDCAVIEGQDFVLQCSVRGTPVPRITWL 479
N + GL+ +S + LKD VIEG VL+C V V + W
Sbjct: 2377 ---GNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWY 2433
Query: 480 LNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
LN + I+ ++ + L I D G Y + +G+V + ++V + K
Sbjct: 2434 LNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLI----VGRVETNCNLSVEKIK- 2488
Query: 537 SRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
++GL DL + V V++S + +V+W EI+
Sbjct: 2489 -------------------IIRGLRDLTCTETQNVVFEVELS-HSGIDVLWNFKDKEIKP 2528
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
S + E G + L + + +D G YT AGE T LTV IS
Sbjct: 2529 SSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAGENMTSGKLTV-------AGGAIS 2577
Query: 657 KP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
KP T + Q + C +A +P WLRDGK L
Sbjct: 2578 KPLTDQTVAESQEAVFECEVA-NPDSKGEWLRDGKHL 2613
Score = 95.9 bits (237), Expect = 3e-19
Identities = 69/265 (26%), Positives = 127/265 (47%), Gaps = 11/265 (4%)
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+G + + + K P P I D V GE + + T +W K
Sbjct: 7869 IGVSEPSEISENVVAKDPD---CKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
K+++ S+ + ++N + L + + + G YT+ +ENKLGS A +N+ V+ P P
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGP 7985
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-TSFNVQ 1323
ASDI SS L+W +DGG+ + Y +E ++ +T+ + + + S+ V+
Sbjct: 7986 CKDIK-ASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVK 8044
Query: 1324 DLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKD---EVEVSDDDEKEPEVDY 1380
DL+P+ EY FRV+A+N G E E + + + P++P D +VEV + + + +
Sbjct: 8045 DLIPNGEYFFRVKAVNKVGGGE-YIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITW 8103
Query: 1381 RTVTINTEQKVSDFYDIEERLGSGK 1405
+ + K+ + I E++ G+
Sbjct: 8104 KPPLYDGGSKIMGY--IIEKIAKGE 8126
Score = 95.9 bits (237), Expect = 3e-19
Identities = 64/229 (27%), Positives = 117/229 (51%), Gaps = 20/229 (8%)
Query: 531 VHEK--KSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 588
VHE+ K+S+ SE + A K + + + + +G ++ + ++G +V W+
Sbjct: 26524 VHEEITKTSQASEEVRTHAEIKAFS-------TQMSINEGQRLVLKANIAG--ATDVKWV 26574
Query: 589 HNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
NG E+ SE++ + G+ +L I++ D G TC + G V+ Q LT+ +
Sbjct: 26575 LNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTLSKELS 26634
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
P FIS+PRS + GQ+VL +C I+G+P P + W ++ + + + + ++ +V+
Sbjct: 26635 DA-PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVY 26692
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPA 757
+L ++ +G+Y I KN G+CS SLM+ LP EP+
Sbjct: 26693 SLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV-------LPLVEEPS 26734
Score = 95.5 bits (236), Expect = 4e-19
Identities = 65/220 (29%), Positives = 111/220 (50%), Gaps = 17/220 (7%)
Query: 1180 VRAGESVELFG-KVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
++AG+++ L + G +W K K I+ S+ ++ ++ S LTI A ++ G
Sbjct: 13893 IKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 13952
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYS 1298
YT+ N G++ V +TV+D P PP G S++ + TL+W DGGS ++SY
Sbjct: 13953 YTITATNPFGTKVEHVKVTVLDVPGPP-GPVEISNVSAEKATLTWTPPLEDGGSPIKSYI 14011
Query: 1299 IEIWDSANKTW----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E +++ W +++ +CR + L+ +EY FRV A+N YG EP Q +
Sbjct: 14012 LEKRETSRLLWTVVSEDIQSCRHVA---TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKM 14068
Query: 1355 VGE-KPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
V P P ++ EVS+ V T T++ ++ V D
Sbjct: 14069 VDRFGPPGPPEKPEVSN-------VTKNTATVSWKRPVDD 14101
Score = 95.5 bits (236), Expect = 4e-19
Identities = 79/293 (26%), Positives = 125/293 (42%), Gaps = 29/293 (9%)
Query: 475 RITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++TW + ++ + T E GVA L+++D D GTY C N G+ S A + V
Sbjct: 25102 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Query: 532 HE-------------KKSSRKSEYL-LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 577
KK R+++ + L P + T P++ + G V V +
Sbjct: 25162 KGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLY-----NKTAYVGENVRFGVTI 25216
Query: 578 SGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ +P P V W +G +I+ ++ + FE + L I V +D YT A N GE
Sbjct: 25217 TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE 25276
Query: 635 VRTQAVLTVQ---EPHDGT-QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
+A LTV P D T +P F + GQSV ++G P PT+ W +DG+
Sbjct: 25277 DSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQ 25336
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
L + + D + L ++ P G Y + N G SCQ L ++
Sbjct: 25337 PLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 94.7 bits (234), Expect = 7e-19
Identities = 64/231 (27%), Positives = 105/231 (45%), Gaps = 5/231 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S+ +F + G TW K I +EN+E+ + L I + G +
Sbjct: 14291 VRAGLSIRIFVPIKGRPAPEVTWTK--DNINLKNRANIENTESFTLLIIPECNRYDTGKF 14348
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +EN G + VN+ V+D P P +DI S+TL W DGGS + +Y +
Sbjct: 14349 VMTIENPAGKKSGFVNVRVLDTPGPVLNLR-PTDITKDSVTLHWDLPLIDGGSRITNYIV 14407
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ T C ++ V L EY FRV A N YG EP++ +E E
Sbjct: 14408 EKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEA 14467
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV 1409
P P D + + D + + + + K++ + +R GS ++ +
Sbjct: 14468 P-SPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHI 14517
Score = 94.7 bits (234), Expect = 7e-19
Identities = 56/186 (30%), Positives = 94/186 (50%), Gaps = 4/186 (2%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PP+ M ++F + V+AGE +++ + G +W K +I+E ++ +++
Sbjct: 19289 PPRVMMD---VKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTD 19345
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
N + LT+ + G Y L ++N G+R VN V+DKP PPAG + + + +L
Sbjct: 19346 NHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSL 19405
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
SW DGG+ + Y +E ++++ W + TS V LL +EY FRV +N
Sbjct: 19406 SWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNK 19465
Query: 1341 YGTSEP 1346
YG EP
Sbjct: 19466 YGVGEP 19471
Score = 94.7 bits (234), Expect = 7e-19
Identities = 131/586 (22%), Positives = 204/586 (34%), Gaps = 111/586 (18%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+ ++ V GQ RF + +P +V W V LQ S+++ + +G+ LEI
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEI 25936
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN----------------------- 257
+ DD G Y + N G+AS A L + G D
Sbjct: 25937 LDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA 25996
Query: 258 --------------RSFVRETKATNSDVRKEVTNVI-SKESKLDSLEAAAKSKNCSSPQR 302
S VRE K+ ++ R+ +++ S +++ S KS S R
Sbjct: 25997 YAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTR 26056
Query: 303 GGSPPWAANSQPQPPR------ESKLESCKDSPRTAPQTPVLQK--------------TS 342
AA +P ES SC P L+K T
Sbjct: 26057 KIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK 26116
Query: 343 SSITLQAARVQPEPRAPGLGVLSPS-GEE--------RKRPAPPRPATFPTR----QPGL 389
T + + VQ V+ S G++ +K + T P R +P +
Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEKAVTSPPRVKSPEPRV 26176
Query: 390 GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSS 449
S + V + P E A E+KP E ++ V P +
Sbjct: 26177 KSPEAVKSPKRVKSP-EPSHPKAVSPTETKPTPTEKVQHLPVS----------APPKITQ 26225
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPV--PRITWLLNGQPIQ----YARSTCEAGVAELHIQD 503
LK A + L C V + + +TW +G+ ++ + G EL I +
Sbjct: 26226 FLK--AEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINN 26283
Query: 504 ALPEDHGTYTCLAENALG------QVSCSAWVTVHEK--------KSSRKSEYLLPVAPS 549
D G Y C G Q A+ ++HEK KS +K+ +
Sbjct: 26284 LTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTTESTVTRKT 26343
Query: 550 KPTAP-------IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
+P AP + + GL D V S V+ +G P P IW +G I + +
Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
+ L I + D+G YTC NSAG V + LT++ D
Sbjct: 26404 SEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKD 26449
Score = 94.4 bits (233), Expect = 9e-19
Identities = 65/215 (30%), Positives = 105/215 (48%), Gaps = 12/215 (5%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ L V+G P TW K + I + ++ +E+ S L + + G Y
Sbjct: 22961 IRAGASLRLMVSVSGRPPPVITWSK--QGIDLASRAIIDTTESYSLLIVDKVNRYDAGKY 23018
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ EN+ G + A V + V D P P ++ S+T++W + DGG+ V +Y +
Sbjct: 23019 TIEAENQSGKKSATVLVKVYDTPGPCPSVK-VKEVSRDSVTITWEIPTIDGGAPVNNYIV 23077
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++A + +K + T C T + + L+ Y FRV N+YG EP + S+ V E
Sbjct: 23078 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEV 23137
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P P ++EV D V TVT+ E+ + D
Sbjct: 23138 PLVPA-KLEVVD-------VTKSTVTLAWEKPLYD 23164
Score = 94.0 bits (232), Expect = 1e-18
Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+A E +++ G T W K + ++E+ + V +S+ + L+I A +E G Y
Sbjct: 18909 VKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTY 18968
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L V N GS + + V+D+P PP G ++ S+T+SW YDGG + +Y +
Sbjct: 18969 ELCVSNSAGSITVPITIIVLDRPGPP-GPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 19027
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ + TW ++ TS + L EY+FRV A N YG S S+ S V E
Sbjct: 19028 EKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESS--AVVAEY 19085
Query: 1359 PEEP 1362
P P
Sbjct: 19086 PFSP 19089
Score = 93.2 bits (230), Expect = 2e-18
Identities = 60/199 (30%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 1181 RAGESVELFGKVTGTQPITCTWM---KFRKQIQESEH-----MKVENSENGSKLTILAAR 1232
+AG + + + G +W K +K +++ H ++E +EN S + I +
Sbjct: 9326 KAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECK 9385
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ H G Y++ +NK G + A + V+D P PP SDI S LSW DGG
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLK-VSDITRGSCRLSWKMPDDDGGD 9444
Query: 1293 AVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
++ Y IE K W ++ C ST+F V DLL + +Y FRVRA N +G P + +
Sbjct: 9445 RIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQ 9504
Query: 1352 LTTVGEK--PEEPKDEVEV 1368
TT + P +P ++++
Sbjct: 9505 RTTARDPIYPPDPPIKLKI 9523
Score = 92.4 bits (228), Expect = 3e-18
Identities = 58/210 (27%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE-HMKVENSE 1221
P A++ P+ + + V AGE+ L + G W K K+++E+ M+++++
Sbjct: 18208 PNASLDPK---YKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTI 18264
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ L + + G Y L + N G++ + + V+D+P PP G + + + L
Sbjct: 18265 QKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYL 18324
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y IE +++ +W +++T ++ ++ V LLP +EY FRV A+N
Sbjct: 18325 AWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNK 18384
Query: 1341 YGTSEPSQESELTTVGE-KPEEPKDEVEVS 1369
YG EP + +T KP P EVS
Sbjct: 18385 YGIGEPLESGPVTACNPYKPPGPPSTPEVS 18414
Score = 92.4 bits (228), Expect = 3e-18
Identities = 59/197 (29%), Positives = 93/197 (47%), Gaps = 7/197 (3%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
T + TV+ T + MP + I P AG VEL + G P +W
Sbjct: 23226 TVTAVTVQDLRVLPTIDLSTMPQKTIHVP------AGRPVELVIPIAGRPPPAASWFFAG 23279
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
+++ESE + VE +KLTI G YTL ++N G+ + + ++DKP PP
Sbjct: 23280 SKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPT 23339
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDL 1325
G +I ++S+T+SW DGG+ + Y +E D+ W ++ + ++F L
Sbjct: 23340 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRL 23399
Query: 1326 LPDHEYKFRVRAINVYG 1342
+EY FRV A N +G
Sbjct: 23400 TEGNEYVFRVAATNRFG 23416
Score = 92.0 bits (227), Expect = 5e-18
Identities = 76/236 (32%), Positives = 105/236 (44%), Gaps = 16/236 (6%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+P+T P + +N+ + EG + E + GYP P VTW+R I S F +
Sbjct: 892 IPVTP-PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQ-S 949
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK---TLGDR 143
G L+I ED G++TC A N +G + L V+ S + V++ T R
Sbjct: 950 GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1009
Query: 144 F--SAPAVETRPSIWGE-------CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTW 194
F S V T S+ E P F TK + EG F C++ G P+P V W
Sbjct: 1010 FVESRDVVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYW 1069
Query: 195 LKGNVPLQPSAR--VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
K VPL R VS +++ G L I DD G YT +V N G+ S SA L
Sbjct: 1070 KKSGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 92.0 bits (227), Expect = 5e-18
Identities = 80/308 (25%), Positives = 119/308 (38%), Gaps = 37/308 (12%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-----RSTCEAGVAELHIQD 503
S+ K+ VIE Q V++ V V W +G I + + E + + I +
Sbjct: 3105 SIKKEVQVIEKQRAVVEFEVNEDDVDA-HWYKDGIEINFQVQERHKYVVERRIHRMFISE 3163
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 563
D G YT +A +R S L AP P LQ L +
Sbjct: 3164 TRQSDAGEYTFVAGR------------------NRSSVTLYVNAPEPPQV---LQELQPV 3202
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
V G +SG P P++ W + F G +++L + E FPED
Sbjct: 3203 TVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAV 3262
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPH----DGTQPWF----ISKPRSVTASLGQSVLISCAI 675
YTCEA N G T A L+V+ P D P + I+ + S GQ C +
Sbjct: 3263 YTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRV 3322
Query: 676 AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECS 735
+G + +D K K + F + Q ED + L + + P G Y + N VG+ S
Sbjct: 3323 SGTDLKVSWYSKDKK--IKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVS 3380
Query: 736 CQVSLMLQ 743
+L L+
Sbjct: 3381 STANLSLE 3388
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/227 (28%), Positives = 106/227 (46%), Gaps = 6/227 (2%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AGE V++ G P T TW K K + +EN+++ S LTI + G Y
Sbjct: 20787 KAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYI 20846
Query: 1241 LLVENKLGS-RQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN +G + + V++ V+D P + ++TL W DGGS + +Y I
Sbjct: 20847 LTIENGVGEPKSSTVSVKVLDTP-AACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E D+ +TW ++ C STSF + DL + FRV A N G EP + +E E
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV 20965
Query: 1359 PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGK 1405
P P ++ + D + + + + ++++ + ER G G+
Sbjct: 20966 P-APIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY--VVERKGKGE 21009
Score = 91.7 bits (226), Expect = 6e-18
Identities = 50/166 (30%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+ G+ +++ ++G T TW K ++++ + V +S + + L+I ++ G Y
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ V N +G + A + + +DKPDPP G D+ + S+TLSW Y GG + +Y +
Sbjct: 16804 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIV 16863
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
+ D+ W + AT T+ V L EY+FR+ A N YG S
Sbjct: 16864 QKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909
Score = 91.3 bits (225), Expect = 8e-18
Identities = 59/183 (32%), Positives = 95/183 (51%), Gaps = 10/183 (5%)
Query: 1179 KVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM------KVENSENGSKLTILAAR 1232
KV+AGE V + VTG W K I++ +V SE ++L+I A
Sbjct: 8912 KVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAV 8971
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+E G YT+ N+LGS V++ V D+P PP +DI++ S L+W +GGS
Sbjct: 8972 REDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL-AVTDIKAESCYLTWDAPLDNGGS 9030
Query: 1293 AVQSYSIEIWDSANK--TWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQE 1349
+ Y I+ D++ K W+E+ T + + L+P+ +Y+FRVRA+N YG S+ +
Sbjct: 9031 EITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKS 9090
Query: 1350 SEL 1352
++
Sbjct: 9091 DKV 9093
Score = 91.3 bits (225), Expect = 8e-18
Identities = 63/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Query: 1157 PAPKTPPKAAMPPQII---QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1213
P P PP++I +Q ++ G+++ L + G TW K +
Sbjct: 10707 PEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA 10766
Query: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASD 1273
+ V + GSKL I A E G Y+L VEN GS+ V + V+DKP PP S+
Sbjct: 10767 RIDV--TPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLE-VSE 10823
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYK 1332
IR S L+W DGGS + +Y +E D A+ W L AT + S + L ++Y
Sbjct: 10824 IRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYL 10883
Query: 1333 FRVRAINVYG 1342
FRV A N YG
Sbjct: 10884 FRVAAENQYG 10893
Score = 91.3 bits (225), Expect = 8e-18
Identities = 65/207 (31%), Positives = 101/207 (48%), Gaps = 10/207 (4%)
Query: 1163 PKAA---MPPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PKA +PP+I + +KV RA ++ LF + G W R + +
Sbjct: 15352 PKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWA--RDHGESLDKAS 15409
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
+E++ + + L + + G Y L VEN GS+ A VN+ V+D P PP ++
Sbjct: 15410 IESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK-VKEVTK 15468
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S+TL+W DGGS +++Y +E +S K + +AT C TS+ V L Y FRV
Sbjct: 15469 TSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRV 15528
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A N YG P++ +E E+P P
Sbjct: 15529 LAENEYGIGLPAETAESVKASERPLPP 15555
Score = 90.5 bits (223), Expect = 1e-17
Identities = 84/289 (29%), Positives = 126/289 (43%), Gaps = 32/289 (11%)
Query: 1180 VRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC 1238
V AG + + V+G P T TW M R QE+ +E + S + I ++ H G
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IETTAISSSMVIKNCQRSHQGV 10095
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPAGTP-CASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y+LL +N+ G R+ + + V+D P P GTP A ++ + S L+W+ DGGS + +Y
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPG-PVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNY 10154
Query: 1298 SIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG 1356
IE +S + W + T + VQ L+ Y FR+ A N G + SE +
Sbjct: 10155 VIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214
Query: 1357 EK---PEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD------FYDIEERL-GSGKF 1406
E PE P+D +EV EV TVT+ D Y +E RL G+ KF
Sbjct: 10215 EPITVPERPED-LEVK-------EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10266
Query: 1407 GQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQC 1455
K T + + KE + +S +N + K C
Sbjct: 10267 -------HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFC 10308
Score = 90.1 bits (222), Expect = 2e-17
Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
+RAG S+ LF + G W K +I+++ + V +S + L + + G Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSF--TSLVLDNVNRYDSGKY 16514
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL +EN G++ A V + V+D P PP ++I S++++W DGGS +++Y +
Sbjct: 16515 TLTLENSSGTKSAFVTVRVLDTPSPPVNLK-VTEITKDSVSITWEPPLLDGGSKIKNYIV 16573
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E ++ K++ + T C S+ + L Y FRV A N YG P+Q ++ V E
Sbjct: 16574 EKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV 16633
Query: 1359 PEEP 1362
P+ P
Sbjct: 16634 PQPP 16637
Score = 90.1 bits (222), Expect = 2e-17
Identities = 67/250 (26%), Positives = 113/250 (45%), Gaps = 15/250 (6%)
Query: 1159 PKTPPKAAMPPQIIQFPE---DQKVRAGESVELFGKVTGTQPIT------CTWMKFRKQI 1209
P P +++++P+ D++ + G V G + T PI C W K + I
Sbjct: 23621 PAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI 23680
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
S+ + SE ++L I A + G Y L++ENK G + + + V+ P+ P G
Sbjct: 23681 --SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPL 23738
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPD 1328
DI+ S+ +SW + DGG+ + Y +E + W + + R TS V+ L +
Sbjct: 23739 EYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLKEN 23798
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEVSDDDEKEPEVDYRTVTI 1385
EY FRV A N +G S+P + E T PE P + EV D + + +
Sbjct: 23799 VEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKD 23858
Query: 1386 NTEQKVSDFY 1395
+ +V+ +Y
Sbjct: 23859 DGGSRVTGYY 23868
Score = 89.4 bits (220), Expect = 3e-17
Identities = 55/193 (28%), Positives = 93/193 (48%), Gaps = 5/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE--DFHFEQRGTQHS 610
AP F Q L + V++GS T +SG P PEV W +G I S +
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
L I V ++G Y+ +A N +G+ + A L V+ + P F+ + +S+T G V
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKA--ETAPPNFVQRLQSMTVRQGSQVR 122
Query: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
+ + G P P V + RDG + + + F++ Q D+++L++ + P +G Y + N
Sbjct: 123 LQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNS 181
Query: 731 VGECSCQVSLMLQ 743
VG + L++Q
Sbjct: 182 VGRATSTAELLVQ 194
Score = 89.4 bits (220), Expect = 3e-17
Identities = 60/221 (27%), Positives = 100/221 (45%), Gaps = 17/221 (7%)
Query: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS 490
+K R + + ++E P F+ L + G++ ++ P P +TW +GQ I+ +
Sbjct: 25179 IKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDN 25238
Query: 491 ------TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLL 544
+ G+ +L I +D YT +A N G+ SC A +TV L
Sbjct: 25239 DKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV----------TLH 25288
Query: 545 PVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQ 604
P P+F + L++ + +G V ++VSG PPP + W +G + +
Sbjct: 25289 PPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIH 25348
Query: 605 RGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
G ++L I++ PEDTG Y A N+AG QA L V+
Sbjct: 25349 EGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389
Score = 87.8 bits (216), Expect = 9e-17
Identities = 144/684 (21%), Positives = 237/684 (34%), Gaps = 121/684 (17%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS-EKNGMQVLEIH 221
F +++ + EG F CK++G P P++ W K ++ R + ++G L I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 222 GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISK 281
V +D G+YT N G A S +L ++ T S +R +S+
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSR 1366
Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKT 341
+ A S SP R + + + ES+LE R VL+
Sbjct: 1367 SP--IRMSPARMSPARMSPARMSPARMSPGRRLEETDESQLE------RLYKPVFVLKPV 1418
Query: 342 S-SSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAAN 400
S + Q AR + K P P TF Q +V+ +
Sbjct: 1419 SFKCLEGQTARF-----------------DLKVVGRPMPETFWFHD----GQQIVNDYTH 1457
Query: 401 RRIPMEGQRDSAFPKFESKPQSQE---VKENQTVKFRCEGLAVME-----VAPSFSSVLK 452
+ + E S + S E V +N+ + + +E V P F LK
Sbjct: 1458 KVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLK 1517
Query: 453 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEA--GVAELHIQDALPE 507
+ + EG ++ G P P I WL N P +Y + E G A L I + +
Sbjct: 1518 NVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQ 1577
Query: 508 DHGTYTCLAENALGQ--VSCSAWVTVHEKKSSRKSEYLLP---------VAP-------- 548
D YT A N G+ C V V + + + ++P AP
Sbjct: 1578 DSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLR 1637
Query: 549 --------------SKPTAPIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGN 592
K P F + L+ L++ +++ G+P V WLH+G
Sbjct: 1638 YGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGK 1697
Query: 593 EIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE------- 645
++ + SL + D+G TC A N G T A L V++
Sbjct: 1698 PLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEE 1757
Query: 646 -------------------PHDGT------------QPWFISKPRSVTASLGQSVLISCA 674
H+G +P + P V G++ C
Sbjct: 1758 SQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCR 1817
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
+ G P P V+W +G+ L + + F V + + + L + + + G+ ++ +N G
Sbjct: 1818 VTGYPQPKVNWYLNGQ-LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVI 1875
Query: 735 SCQVSLMLQNSS--ARALPRGREP 756
+V L +Q L R EP
Sbjct: 1876 EHKVKLEIQQREDFRSVLRRAPEP 1899
Score = 87.8 bits (216), Expect = 9e-17
Identities = 62/207 (29%), Positives = 97/207 (46%), Gaps = 11/207 (5%)
Query: 1163 PKAAMPPQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMK--FRKQIQESEHMK 1216
PK + P I + VRAG + LF V G TW K +++ +
Sbjct: 12100 PKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQ--- 12156
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
V+ + + L I + ++ G Y+L + N G + VN+ V+D P P + SD+
Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLK-VSDVTK 12215
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRV 1335
+S +SW DGGS V Y +E ++ KTW + + TSF+V +L+P +EY FRV
Sbjct: 12216 TSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12275
Query: 1336 RAINVYGTSEPSQESELTTVGEKPEEP 1362
A+N YG P+ + + EP
Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEP 12302
Score = 87.8 bits (216), Expect = 9e-17
Identities = 56/211 (26%), Positives = 94/211 (44%), Gaps = 11/211 (5%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQK---------VRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
P P P I+ PE + +RAG ++ L+ V G P TW K +
Sbjct: 13178 PSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNL 13237
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
++ + +++++ + L + G Y L +EN G ++ + + V+D P PP
Sbjct: 13238 RDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNV- 13296
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPD 1328
+I S ++W DGGS + +Y ++ D+ K+W + T C TSF V +L
Sbjct: 13297 TVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEG 13356
Query: 1329 HEYKFRVRAINVYGTSEPSQESELTTVGEKP 1359
Y FRV A N YG +P + + + P
Sbjct: 13357 KSYFFRVFAENEYGIGDPGETRDAVKASQTP 13387
Score = 87.8 bits (216), Expect = 9e-17
Identities = 66/230 (28%), Positives = 106/230 (46%), Gaps = 15/230 (6%)
Query: 1168 PPQIIQFPEDQKV---RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I + +KV RA ++ LF + G W K + ++ ++E + + +
Sbjct: 18607 PPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGIL--TDRAQIEVTSSFT 18664
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L I + G Y L +EN GS+ A VN+ V+D P P +++ S+TLSW
Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIR-EVKKDSVTLSWE 18723
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DGG+ + +Y +E ++ K + + C T+F +++L Y FRV A N YG
Sbjct: 18724 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Query: 1344 SEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
P++ +E V E P P V +V T TI E+ SD
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTLV--------DVTRNTATIKWEKPESD 18825
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/184 (30%), Positives = 89/184 (48%), Gaps = 4/184 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VRAG S + G TW R++ + ++ +++E N ++L+I + G Y
Sbjct: 17539 VRAGGSARIHIPFKGRPTPEITWS--REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 17596
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
L +EN GS+ A V + V+D P PP ++R S L W DGG+ V++Y I
Sbjct: 17597 ILKLENSSGSKSAFVTVKVLDTPGPPQNL-AVKEVRKDSAFLVWEPPIIDGGAKVKNYVI 17655
Query: 1300 EIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
+ +S K + +++ C TSF V++L Y FRV A N +G P + + E
Sbjct: 17656 DKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP 17715
Query: 1359 PEEP 1362
P P
Sbjct: 17716 PSPP 17719
Score = 87.0 bits (214), Expect = 1e-16
Identities = 46/168 (27%), Positives = 85/168 (50%), Gaps = 1/168 (0%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
++AGE +++ V G +W+K + ++++ + VE + + L I ++ G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
T+ N G+ +++ V++KP PP G ++ + + +SW +Y GG + +Y +
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 17945
Query: 1300 EIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
E D+ TW + AT T+ + L EY+FR+ A N YG S P
Sbjct: 17946 EKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 17993
Score = 85.9 bits (211), Expect = 3e-16
Identities = 67/238 (28%), Positives = 104/238 (43%), Gaps = 21/238 (8%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG- 77
V P++ DS P FI N I G A V G P+P++ W NG +T
Sbjct: 3443 VYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSAD 3502
Query: 78 -RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVV 136
+F+ D SL+I ED G+YTC A+N G T+ ++ K +
Sbjct: 3503 YKFVFD---GDDHSLIILFTKLEDEGEYTCMASNDYGK-------TICSAYLK-----IN 3547
Query: 137 SKTLGDRFS---APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVT 193
SK G + + + ++ + G CPP F +L + +G F + G P P VT
Sbjct: 3548 SKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607
Query: 194 WLKGNVPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
W K N L S + + NG ++ ++D G+Y C N G+++ +AEL +
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 85.5 bits (210), Expect = 4e-16
Identities = 60/221 (27%), Positives = 94/221 (42%), Gaps = 31/221 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+L P + EG TA+F+ +V G P P+ W +GQ I + + GT SL+
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I D G++T A N +G ++V LTVE AVE
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVE-----------------------AVE-- 1505
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--ARVSVS 210
+ P F KL V +KEG + TG P P + WLK + + P ++ +
Sbjct: 1506 ----HQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIE 1561
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
G L+I D YT +N +G+ + +++++
Sbjct: 1562 GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602
Score = 85.1 bits (209), Expect = 6e-16
Identities = 178/820 (21%), Positives = 302/820 (36%), Gaps = 113/820 (13%)
Query: 367 SGEERKRPAPP--RPATFPTRQPGLGSQDVVSKAANRR-IPMEGQRDSAFPKFESKPQSQ 423
SG+ PA P P PT +P + + ++ +R I M R S ++
Sbjct: 1330 SGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPA 1389
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
+ + ++ E P F +EGQ V G P+P W +GQ
Sbjct: 1390 RMSPGRRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQ 1449
Query: 484 PI--QYARSTC--EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK 539
I Y E G L I A P D G +T +A+N G+ S S +TV + K
Sbjct: 1450 QIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVK 1509
Query: 540 SEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED 599
P+F++ L ++ + +GS++ M V+ +GNP P+++WL N + I +
Sbjct: 1510 --------------PMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKY 1555
Query: 600 FHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK 657
GT + +L I +D+ YT A N AG T+ + V+ +P
Sbjct: 1556 PKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEP----- 1610
Query: 658 PRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF------TLV 711
R + G + IA +H LR G+ ++ ++ + + F +L
Sbjct: 1611 ERKLIIPRG--TYRAKEIAAPELEPLH-LRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLR 1667
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGR---EPASCEDLCGGGVG 768
LK+ P H +E L +G+ + V + A R R E C G
Sbjct: 1668 LKRFGPAH---FECRL-TPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYS 1723
Query: 769 ADGG-----GSDRYGSLRPGWP--ARGQGWLEEED--GEDVRGVLKRRVETRQHTEEAIR 819
D G +++YG+ + + L EE E +G+ + R E A+
Sbjct: 1724 RDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALT 1783
Query: 820 QQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKT--------VSE 871
+Q + K+ L + ++ + E FR + +PK + +
Sbjct: 1784 GVTTDQKE------KQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRK 1837
Query: 872 EER------KVHSPQQVDFRS--VLAKKGTSKTP---VPEKVPPPKPATPDFRSVLGGKK 920
+R +H VD +S K T++ P + KV DFRSVL
Sbjct: 1838 SKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAP 1897
Query: 921 KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 980
+ E L + + +P+ + K V K AE + + +E L+
Sbjct: 1898 EPRPEFHVHEPGKLQFEVQKVDRPVDTTE----TKEVVKLKRAERITHEKVPEESEELRS 1953
Query: 981 MGNAKPDE---------NLKSASKEELKKDVKNDVNCKRGH--AGTTDNEKRS---ESQG 1026
+ +E LKS K+E +++ + H T+ EK++ E +
Sbjct: 1954 KFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKI 2013
Query: 1027 TAPAFK----------------QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTL 1069
T P FK +++Q V +G + +V P W NG K
Sbjct: 2014 TIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIE 2073
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQ 1109
++ + E ++C + I ED A N AG+
Sbjct: 2074 RSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGE 2113
Score = 84.7 bits (208), Expect = 7e-16
Identities = 150/724 (20%), Positives = 239/724 (33%), Gaps = 89/724 (12%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVR--GYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
+ P F +L +K A FE R+ G P V W +G+P+ + R + G
Sbjct: 1655 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-INEFGY 1713
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV--EGSFAKQLGQPVVSKTLGDRFSA 146
SL + D G TC ATN G + L V E S ++ P K L
Sbjct: 1714 CSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEEL 1773
Query: 147 PAVETRPSIWG-------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV 199
+ ++ G + P V V EG+ RF C++TG PQP+V W
Sbjct: 1774 ERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ 1833
Query: 200 PLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRS 259
++ S R V +G+ L+I D G N G +L IQ + RS
Sbjct: 1834 LIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDF-RS 1891
Query: 260 FVRETKATNSDVRKEVTNVISKE-SKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
+R + + E K+D ++K +R +
Sbjct: 1892 VLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEEL 1951
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
SK + + T V K+ ++ + EE+K A
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEG 2011
Query: 379 PATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGL 438
T PT +P +I + ++ PK + QSQ V + FR
Sbjct: 2012 KITIPTFKPD-------------KIELSPSMEA--PKIFERIQSQTVGQGSDAHFRVR-- 2054
Query: 439 AVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC----EA 494
V G P P W NG I+ + E
Sbjct: 2055 -----------------------------VVGKPDPECEWYKNGVKIERSDRIYWYWPED 2085
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
V EL I+D ED + A N G+ S A++ V K+
Sbjct: 2086 NVCELVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ-----------------LI 2128
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F Q L D+ + + + P +V W +G E+ E + + H L I
Sbjct: 2129 TFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSIL 2188
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ D Y+C V+T A L V +G F+ + + + S + C
Sbjct: 2189 TIDTSDAEDYSCVLVEDE-NVKTTAKLIV----EGAVVEFVKELQDIEVPESYSGELECI 2243
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ + W + L K G + + L +K V G+Y ++ + C
Sbjct: 2244 VSPENIEG-KWYHNDVEL-KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTTC 2301
Query: 735 SCQV 738
++
Sbjct: 2302 KLKM 2305
Score = 84.0 bits (206), Expect = 1e-15
Identities = 65/256 (25%), Positives = 111/256 (43%), Gaps = 35/256 (13%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ VA + S +L V+ E P + + + ++ G A+F + G P+
Sbjct: 3170 GEYTFVAGRNRSSVTLYVNAP--------EPPQVLQELQPVTVQSGKPARFCAVISGRPQ 3221
Query: 62 PQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P+++W++ Q +++G + FL D ++L++ ED YTCEA N G +
Sbjct: 3222 PKISWYKEEQLLSTGFKCKFLHD---GQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSA 3278
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
L+VE P V + PP T L V EGQ R
Sbjct: 3279 SLSVE---------------------VPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPAR 3317
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
F C+++G +V+W + ++PS +++ LEI +D G YT + N
Sbjct: 3318 FQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAV 3376
Query: 240 GKASMSAELSIQGLDS 255
G+ S +A LS++ +S
Sbjct: 3377 GQVSSTANLSLEAPES 3392
Score = 84.0 bits (206), Expect = 1e-15
Identities = 46/155 (29%), Positives = 76/155 (49%), Gaps = 1/155 (0%)
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
+ G + +W K + + VE+S + L + ++ G YT+ ++N G+++
Sbjct: 13509 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+++ VV KP P G ++ + ++TL W DGGS + +Y +E DS N W
Sbjct: 13569 GTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVT 13628
Query: 1312 LATC-RSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
A+ + T+F V L EY FRV A N YG E
Sbjct: 13629 CASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13663
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 87/182 (47%), Gaps = 4/182 (2%)
Query: 1168 PPQIIQ--FPEDQK-VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
PP+I FP VRAG ++++ ++G T + ++ + E +
Sbjct: 19976 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENL 20035
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
+ + + G Y + N G+ +A +N+ V+D+P PP G SDI S+TL W
Sbjct: 20036 TINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWE 20095
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
YDGGS V +Y + +++ W E+ AT T V L EY+FR++A N +G
Sbjct: 20096 PPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGI 20155
Query: 1344 SE 1345
S+
Sbjct: 20156 SD 20157
Score = 83.2 bits (204), Expect = 2e-15
Identities = 49/183 (26%), Positives = 90/183 (49%), Gaps = 5/183 (2%)
Query: 1169 PQIIQFPEDQK----VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
P I++F + +++GES+ + V G TW K +I++ +M++ + +
Sbjct: 21458 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGST 21517
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWY 1284
L + A ++H G YT+ +N GS +A++ + V D P G ++I +TL W
Sbjct: 21518 SLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWD 21577
Query: 1285 GSSYDGGSAVQSYSIEIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGT 1343
DG + + Y IE +++ W + C + S+ L+ +EY+FRV A+N +G
Sbjct: 21578 APLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGV 21637
Query: 1344 SEP 1346
P
Sbjct: 21638 GRP 21640
Score = 82.8 bits (203), Expect = 3e-15
Identities = 112/474 (23%), Positives = 180/474 (37%), Gaps = 54/474 (11%)
Query: 813 HTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTV--- 869
H EE+ QQ + +++ ++S ++E + PA + + + VKP+ +
Sbjct: 676 HLEESYAQQTTLEYGYKE----RISAAKVAEPPQR--PASEPHV---VPKAVKPRVIQAP 726
Query: 870 SEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP-PKPATPDFRSVLGGKKKLPAENGS 928
SE K + + S + K T V P+ A+P F K +P
Sbjct: 727 SETHIKTTDQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTV---SKISVPKTEHG 783
Query: 929 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAET--LKPMGNAKP 986
A + K LS + + + + A T+KP AE L A
Sbjct: 784 YEASIAGSAIATLQKELSATSSA---QKITKSVKAPTVKPSETRVRAEPTPLPQFPFADT 840
Query: 987 DENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQG-------------------- 1026
+ KS + E+KK+V + GTT E+R E
Sbjct: 841 PDTYKSEAGVEVKKEVGVSIT------GTTVREERFEVLHGREAKVTETARVPAPVEIPV 894
Query: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSV 1086
T P L++V V EG+ + L+C +S P T+ W ++++ ++ + + +
Sbjct: 895 TPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARL 954
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSC--QVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
I +A ED G + C A N+AG SC V V + E T E + K +
Sbjct: 955 MIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESR 1014
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
+D ++ ++ A P A P I P QK+ G SV +V G W K
Sbjct: 1015 DVVMTDTSLTEEQAGPGEPAA---PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKK 1071
Query: 1205 FRKQIQESEHMKVE-NSENGS-KLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256
+ KV N + G KL I + G YT++V NK G A +L
Sbjct: 1072 SGVPLTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125
Score = 82.4 bits (202), Expect = 4e-15
Identities = 101/443 (22%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 1017 DNEKRSESQ-GTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFI 1075
D E R++ + AP K QD+ V GK L + + P A W + L T
Sbjct: 6490 DKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTID 6549
Query: 1076 ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSR 1135
+++ S + +K D+G YK V +N G+AE + V D P
Sbjct: 6550 TTAEQTSFRILEAKKG---DKGRYKIVLQNKHGKAEGFINLKVIDVPG------------ 6594
Query: 1136 RPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGT 1195
PV E T + + ++ + G S ++ G V
Sbjct: 6595 -------PVRNLEVTETFDGE---------------VSLAWEEPLTDGGS-KIIGYVVER 6631
Query: 1196 QPITC-TWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGC-YTLLVENKLGSRQAQ 1253
+ I TW+ + + E + G + + + G + +N + +R
Sbjct: 6632 RDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKY 6691
Query: 1254 VNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
D P PP +D+ ++L+W YDGG+ + +Y IE+ D + W
Sbjct: 6692 ------DVPGPPLNVTI-TDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6744
Query: 1314 TCRST--SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
T R+ S V D++ EY FRVRA N G +PS + V + E P V ++
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSS 6804
Query: 1372 DEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQV---FRLVEKKTRKVW----AGK 1424
D+ + V + + I ER GK + +LV + T KV K
Sbjct: 6805 DQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNK 6864
Query: 1425 FFKAYSAKEKENIRQEISIMNCL 1447
+ SA+ K + I+ L
Sbjct: 6865 YLYRVSAENKAGVSDPSEILGPL 6887
Score = 82.4 bits (202), Expect = 4e-15
Identities = 53/185 (28%), Positives = 85/185 (45%), Gaps = 4/185 (2%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
V+AG S + G W K ++ + V+ +++ + LTI A + G Y
Sbjct: 19701 VKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAY--VDTTDSRTSLTIENANRNDSGKY 19758
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
TL ++N L + + + V+D P PP D+ S LSW DGG+ V++Y I
Sbjct: 19759 TLTIQNVLSAASLTLVVKVLDTPGPPTNI-TVQDVTKESAVLSWDVPENDGGAPVKNYHI 19817
Query: 1300 EIWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
E +++ K W + C S+ V +L Y FRV N +G P++ E + EK
Sbjct: 19818 EKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITEK 19877
Query: 1359 PEEPK 1363
P P+
Sbjct: 19878 PSPPE 19882
Score = 82.4 bits (202), Expect = 4e-15
Identities = 62/203 (30%), Positives = 92/203 (45%), Gaps = 4/203 (1%)
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGN 592
E + S SE + P + AP F + L +L V S T+ +V+G+P P V W G
Sbjct: 24410 ESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGK 24469
Query: 593 EI-QESEDFHFEQ-RGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGT 650
EI + + ++ +G H L I V +D Y A N G V A L V+ P
Sbjct: 24470 EIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIH 24529
Query: 651 QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTL 710
P + +V A G+ V I +G P P + W + G+ L + GH++V+ +L
Sbjct: 24530 LPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNGHYQVIVTRSFTSL 24588
Query: 711 VLKK-VQPWHAGQYEILLKNRVG 732
V V+ AG Y + KNR G
Sbjct: 24589 VFPNGVERKDAGFYVVCAKNRFG 24611
Score = 82.0 bits (201), Expect = 5e-15
Identities = 70/273 (25%), Positives = 106/273 (38%), Gaps = 32/273 (11%)
Query: 23 RVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG---R 78
R D+M L E P F LP N G +F + +PEP VTW+++GQ I G +
Sbjct: 25182 RTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKK 25241
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ + +G + L I++V +D +YT A N G +LTV L P
Sbjct: 25242 YTFESD-KGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV------TLHPPPTDS 25294
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
TL P F L +EGQ F +++G P P + W K
Sbjct: 25295 TL-------------------RPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335
Query: 199 VPLQPSARVS-VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSAN 257
PL + + E L I +D G Y N +G S A L ++ L
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Query: 258 RSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
+ F + + V+K++ + L E+
Sbjct: 25396 QEF-KSKEEHERHVQKQIDKTLRMAEILSGTES 25427
Score = 81.6 bits (200), Expect = 6e-15
Identities = 59/221 (26%), Positives = 100/221 (45%), Gaps = 7/221 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRK--QIQESEHMKVENSENGSKLTILAARQEHCG 1237
V+AG+++ L V G W K + + S +K++ + SK ++ A++ G
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775
Query: 1238 CYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
Y + N GS A + V+DKP P D+ S T+ W DGG +Q+Y
Sbjct: 11776 KYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIV-DVSSDRCTVCWDPPEDDGGCEIQNY 11834
Query: 1298 SIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESEL--TT 1354
+E ++ W AT + V L+ +EY FRVRA N GT P++ + T
Sbjct: 11835 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKT 11894
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFY 1395
+KP P D EV+ ++E V + + + ++ ++
Sbjct: 11895 KYDKPGRP-DPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 11934
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/193 (27%), Positives = 89/193 (46%), Gaps = 4/193 (2%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
AP + + D+ G ++ Q+ G P P++ W G E+ +S + G H+L
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
+ ED G YTC A N GEV T + L +Q P + K + A +G ++ +
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ-FHPGYPLKEKYYGA-VGSTLRLH 24152
Query: 673 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ-PWHAGQYEILLKNRV 731
G P P + W G+ L +++ + + E LV+K VQ HAG+Y++ L N
Sbjct: 24153 VMYIGRPVPAMTWFH-GQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVF 24211
Query: 732 GECSCQVSLMLQN 744
G + + +Q+
Sbjct: 24212 GTVDAILDVEIQD 24224
Score = 81.6 bits (200), Expect = 6e-15
Identities = 75/315 (23%), Positives = 116/315 (36%), Gaps = 74/315 (23%)
Query: 12 ISKTSLSVDPSRVD---SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
ISKT + + D S L++APAFI PR+ I EG F + G P P++ W +
Sbjct: 26613 ISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFK 26672
Query: 69 NGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL------- 121
N PI+ + R +SL I D GKYT +A N G T L
Sbjct: 26673 NNLPISISSNVSISRS-RNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731
Query: 122 --------------TVEGSFAKQLGQPVVSKTLGD---------------RFSAPAVETR 152
+++GSF+ Q Q SK +F++ + ++
Sbjct: 26732 EPSREVVLRTSGDTSLQGSFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSM 26791
Query: 153 PSIWGE--------------------------------CPPKFATKLGRVVVKEGQMGRF 180
S+ PPK + + EG++
Sbjct: 26792 SSMQESFVEMSSSSFMGISNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTV 26851
Query: 181 SCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
+C TG P P+VTW G + Q R + + + L I V + D G+YT + N
Sbjct: 26852 ACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNE 26911
Query: 239 SGKASMSAELSIQGL 253
G S + + I+ +
Sbjct: 26912 FGSDSATVNIHIRSI 26926
Score = 81.3 bits (199), Expect = 8e-15
Identities = 123/536 (22%), Positives = 192/536 (35%), Gaps = 142/536 (26%)
Query: 5 KLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQV 64
K + I+KTS + + R + E AF + I EG + + G + V
Sbjct: 26521 KSIVHEEITKTSQASEEVRTHA----EIKAF---STQMSINEGQRLVLKANIAGATD--V 26571
Query: 65 TWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
W NG +T+ + G+ G+ +L I D G TC + G + +LT+
Sbjct: 26572 KWVLNGVELTNSEEYRY--GVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDLTL 26629
Query: 124 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCK 183
SK L D APA ++P + EGQ F+C+
Sbjct: 26630 -------------SKELSD---APAFISQPRSQN--------------INEGQNVLFTCE 26659
Query: 184 ITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKAS 243
I+G P P++ W K N+P+ S+ VS+S + LEI + D G YT N G+ S
Sbjct: 26660 ISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCS 26719
Query: 244 MSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA--AAKSKNCSSPQ 301
+A L + L V + V+ + S SL+ +++S S+ +
Sbjct: 26720 ATASLMVLPL-----------------VEEPSREVVLRTSGDTSLQGSFSSQSVQMSASK 26762
Query: 302 RGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
+ S ++S E K S ++ Q ++ +SSS +
Sbjct: 26763 QEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSF---------------M 26807
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
G+ + + E S + KA R IP PK E+ P
Sbjct: 26808 GISNMTQLE-------------------SSTSKMLKAGIRGIP---------PKIEALPS 26839
Query: 422 SQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481
+ E + V+ VA C+ G P P +TW
Sbjct: 26840 DISIDEGK----------VLTVA---------------------CAFTGEPTPEVTWSCG 26868
Query: 482 GQPI---QYARSTCE--AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
G+ I + R E + L I D +D G YT N G S SA V +H
Sbjct: 26869 GRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFG--SDSATVNIH 26922
Score = 80.9 bits (198), Expect = 1e-14
Identities = 58/209 (27%), Positives = 95/209 (45%), Gaps = 9/209 (4%)
Query: 1162 PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
PPKA + ++ + +RAG + L V G W K K++ E + ++ +
Sbjct: 22546 PPKAELDARL--HGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603
Query: 1222 NGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTL 1281
+ I + G YTL V+N G++ V + V+D P P G S + TL
Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPG-PCGKLTVSRVTQEKCTL 22662
Query: 1282 SWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
+W DGG+ + Y +E +++ W + C + S+ V L+ ++EY FRVRA+N
Sbjct: 22663 AWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNK 22722
Query: 1341 YG-----TSEPSQESELTTVGEKPEEPKD 1364
YG SEP T+ P P++
Sbjct: 22723 YGPGVPVESEPIVARNSFTIPSPPGIPEE 22751
Score = 80.1 bits (196), Expect = 2e-14
Identities = 170/794 (21%), Positives = 285/794 (35%), Gaps = 143/794 (18%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A++ S +L +V +PL FI P ++ + E AKFE V P+
Sbjct: 5321 GEVSFQAANAKSAANL-----KVKELPLI----FITPLSDVKVFEKDEAKFECEVSREPK 5371
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGA------ 114
W + Q IT RF L+ G + + + A +E + + E + SG
Sbjct: 5372 T-FRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKHTSGKLIIEGI 5430
Query: 115 --------RQVTVELTVEGSFAKQLGQPVV----------------------SKTLGDRF 144
+ VT + F +L + KT F
Sbjct: 5431 RLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITF 5490
Query: 145 SAPAVETRPSIWGEC--------------PPKFATKLGRVVVKEGQMGRFSCKITGRPQP 190
+++ I E P F KL E C+I+ P
Sbjct: 5491 KDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP 5550
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V W K ++PS + ++L + + D+G YTC G S +L I
Sbjct: 5551 -VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDI 5605
Query: 251 QGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAA 310
+ +R + +V + T E D + A K K + Q
Sbjct: 5606 E-----DREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQ--------- 5651
Query: 311 NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEE 370
+ E K+ S QT + ++++ +A ++ +PR +G+L P +
Sbjct: 5652 TPDCEIKEEGKIHSLVLHNCRLDQTGGVDFQAANVK-SSAHLRVKPRV--IGLLRPLKDV 5708
Query: 371 RKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQT 430
ATF L +D+ + + +E D P+ E K + +++
Sbjct: 5709 TVTAG--ETATFDCE---LSYEDIPVEWYLKGKKLEPS-DKVVPRSEGKVHTLTLRD--- 5759
Query: 431 VKFRCEG--------------LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRI 476
VK G L V E F+ L+D V EG VL+C V ++
Sbjct: 5760 VKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKV 5818
Query: 477 TWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
W NG I ++ + V +L I D PED TYTC A++ + SC+ V
Sbjct: 5819 KWFKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDAKDF--KTSCNLNVV--- 5873
Query: 534 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
P FL+ L+DL+V + ++S +V W +G E
Sbjct: 5874 -----------------PPHVEFLRPLTDLQVREKEMARFECELS-RENAKVKWFKDGAE 5915
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPW 653
I++ + + +G L I + +D Y+CE + RT +LTV E +
Sbjct: 5916 IKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTA----RTSGMLTVLE----EEAV 5967
Query: 654 FISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLK 713
F ++ S ++ + C ++ P V W + + + +TG +E+L LV++
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVS-KPGAEVIWYKGDEEII-ETGRYEILTEGRKRILVIQ 6025
Query: 714 KVQPWHAGQYEILL 727
AG Y L
Sbjct: 6026 NAHLEDAGNYNCRL 6039
Score = 80.1 bits (196), Expect = 2e-14
Identities = 181/813 (22%), Positives = 280/813 (34%), Gaps = 141/813 (17%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L AP L R+ + G +F V+ P +V W+ NG + + G
Sbjct: 25873 LDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYT-NTSGV 25931
Query: 89 FSLVIHAVHEEDRGKY---------------TCEATNGSGA------------RQVTVEL 121
+L I H +D G Y T + T G R V EL
Sbjct: 25932 LTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPEL 25991
Query: 122 TVEGSFA----KQLGQPVVSKTLGDRFSAPAVETRPSIWG-------------------- 157
T ++A K+ + S ++ + + ETR S+
Sbjct: 25992 TRTEAYAVSSFKKTSEMEASSSVRE-VKSQMTETRESLSSYEHSASAEMKSAALEEKSLE 26050
Query: 158 ----------ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARV 207
+ TK + V EG+ RFSC G P P VTWL+ L SAR
Sbjct: 26051 EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARH 26110
Query: 208 SVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
V+ EI V D G Y+ +V N GK L+IQ ++ V E KA
Sbjct: 26111 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ------KARVTE-KAV 26163
Query: 268 NSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD 327
S R V S E ++ S EA K SP+ P P + + E +
Sbjct: 26164 TSPPR-----VKSPEPRVKSPEAVKSPKRVKSPE----PSHPKAVSPTETKPTPTEKVQH 26214
Query: 328 SPRTAPQ--TPVLQ-KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAP-----PRP 379
P +AP T L+ + S I V+ G++ K
Sbjct: 26215 LPVSAPPKITQFLKAEASKEIAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSAD 26274
Query: 380 ATFPTRQPGLGSQDV---------VSKAANRRIPMEGQRDSAFPKFESK----PQSQEVK 426
T+ + L D + + GQ + + SK +S +
Sbjct: 26275 GTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKT 26334
Query: 427 ENQTVKFRCEGLAVMEVA--PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRIT--WLLNG 482
TV + E A ++ P + L+D V D V + +V+ T PR T W +G
Sbjct: 26335 TESTVTRKTEPKAPEPISSKPVIVTGLQDTTV--SSDSVAKFAVKATGEPRPTAIWTKDG 26392
Query: 483 QPI----QYARSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 537
+ I +Y S + G E+H D D G YTC +N+ G VS S +T+ K +
Sbjct: 26393 KAITQGGKYKLSEDKGGFFLEIHKTDT--SDSGLYTCTVKNSAGSVSSSCKLTIKAIKDT 26450
Query: 538 RKSEY-LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
+ + P +Q K + ++ M+ ++ +++
Sbjct: 26451 EAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMS---EAKSQEKLALKEEASKVLI 26507
Query: 597 SEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
SE+ ++ SL V E T T ++ EVRT A + S
Sbjct: 26508 SEEV---KKSAATSLEKSIVHEEITKTS-----QASEEVRTHAEIKA-----------FS 26548
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
S+ GQ +++ IAG V W+ +G L + + D TL +K+
Sbjct: 26549 TQMSINE--GQRLVLKANIAG--ATDVKWVLNGVELTNSEEYRYGVSGSDQ-TLTIKQAS 26603
Query: 717 PWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 749
G + K + G CQ L L + A
Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELSDA 26636
Score = 79.7 bits (195), Expect = 2e-14
Identities = 48/163 (29%), Positives = 80/163 (49%), Gaps = 1/163 (0%)
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
+AG+++++ V G T TW K + +++++ + E + + L I + G Y
Sbjct: 14581 KAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYP 14640
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
L N +G + + V D P PP G ++ S +T SW DGG + +Y +E
Sbjct: 14641 LTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVE 14700
Query: 1301 IWDSANKTWKELA-TCRSTSFNVQDLLPDHEYKFRVRAINVYG 1342
+ + + TW ELA T T++ L EY+FRV+A N YG
Sbjct: 14701 MRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYG 14743
Score = 79.3 bits (194), Expect = 3e-14
Identities = 39/112 (34%), Positives = 62/112 (55%), Gaps = 1/112 (0%)
Query: 1669 EEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS 1728
EED + ++E + V+ F I++ ++EG F CK+ GYP P++ W+KD +
Sbjct: 1226 EEDGEEKMAVDISESEA-VESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKR 1284
Query: 1729 IRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I+ +Q+D+ +DG SL I V +D+ YT A N G A C+ +L VE
Sbjct: 1285 IKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVE 1336
Score = 79.0 bits (193), Expect = 4e-14
Identities = 148/719 (20%), Positives = 276/719 (38%), Gaps = 111/719 (15%)
Query: 35 FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVI 93
F+ P +L ++E A+FE + +V W ++G I G ++ D +G LVI
Sbjct: 5879 FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKY--DIISKGAVRILVI 5935
Query: 94 HAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRP 153
+ +D +Y+CE + +TV L E F K L VS+T
Sbjct: 5936 NKCLLDDEAEYSCEVRTARTSGMLTV-LEEEAVFTKNLANIEVSET-------------- 5980
Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
+ C+++ +P +V W KG+ + + R + +
Sbjct: 5981 ----------------------DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEG 6017
Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNG--SGKASMSAELSIQGLDSANRSFVRETKATNSDV 271
++L I + +D G Y C + + GK + EL+ + + + E +
Sbjct: 6018 RKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVH-ELAAEFISKPQNLEILEGE------ 6070
Query: 272 RKEVTNVISKES-----KLD--SLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLES 324
+ E ISKES K D +LE+ K + ++ A Q + +
Sbjct: 6071 KAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGA 6130
Query: 325 CKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPT 384
R A V++K + L+ RV+ + ++ G + K A F +
Sbjct: 6131 A----RAAAHLTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKW-FRNEEAIFDS 6185
Query: 385 RQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVA 444
+ + +D+V R ++ Q + + + + + VK + E L ++E
Sbjct: 6186 SKYIILQKDLVYTLRIRDAHLDDQAN--YNVSLTNHRGENVKSAANLIVEEEDLRIVEP- 6242
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---I 501
LKD +E + C V V + W NG+ + + H I
Sbjct: 6243 ------LKDIETMEKKSVTFWCKVNRLNVT-LKWTKNGEEVPFDNRVSYRVDKYKHMLTI 6295
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+D D G Y VT + KS +E L+ AP++ F++ L
Sbjct: 6296 KDCGFPDEGEYI---------------VTAGQDKSV--AELLIIEAPTE-----FVEHLE 6333
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D V + + Q+S V W NG EI+E + + FE+ G+ H L I++ +D
Sbjct: 6334 DQTVTEFDDAVFSCQLS-REKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDE 6392
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE-PHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPF 680
Y C + +++A L V+E P + +P P+ + + G V+ + D
Sbjct: 6393 CEYAC----GVEDRKSRARLFVEEIPVEIIRP-----PQDILEAPGADVVFLAELNKDKV 6443
Query: 681 PTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
V WLR+ + + H +++ + L + ++P G+Y + K++ +++
Sbjct: 6444 -EVQWLRNNMVVVQGDKH-QMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELA 6500
Score = 78.6 bits (192), Expect = 5e-14
Identities = 68/246 (27%), Positives = 109/246 (44%), Gaps = 42/246 (17%)
Query: 1156 KPAPKTPPKAAMPPQIIQFPE-----DQKVRAGESVELFGKVTGTQPITCTWMKFRK--- 1207
+P+ TPP A+ P I P+ +V+ G+ + L ++G+ T TW+K
Sbjct: 8167 EPSRATPPTKAVDP--IDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIV 8224
Query: 1208 -----------------QIQESE--------HMKVENSENG-SKLTILAARQEHCGCYTL 1241
++QE E + ++NS+ G S+L + + + G Y +
Sbjct: 8225 PEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMI 8284
Query: 1242 LVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI 1301
VEN G +A ++V+D P PP DIR +S+ W DGGS + +Y++E
Sbjct: 8285 KVENDHGIAKAPCTVSVLDTPGPPINF-VFEDIRKTSVLCKWEPPLDDGGSEIINYTLEK 8343
Query: 1302 WDSA--NKTWKEL-ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK 1358
D + W + +T R ++V L+ EY FRVRA N +G P L V +
Sbjct: 8344 KDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPL--VAKD 8401
Query: 1359 PEEPKD 1364
P P D
Sbjct: 8402 PFGPPD 8407
Score = 78.2 bits (191), Expect = 7e-14
Identities = 56/212 (26%), Positives = 97/212 (45%), Gaps = 7/212 (3%)
Query: 1159 PKTPPKAAMPP--QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
P T A + P + F + +V + + TG T TW K ++ + +K
Sbjct: 6886 PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK 6945
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS 1276
++ ++L I + + G YTL +EN++ + ++++ V+ +P P DI
Sbjct: 6946 MKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELK-FGDITK 7004
Query: 1277 SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW-KELATCRSTSFNVQDLLPDHEYKFRV 1335
S+ L+W DGGS + Y +E + + KTW K + F V DL+ EY F+V
Sbjct: 7005 DSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKV 7064
Query: 1336 RAINVYGTSEPSQESE---LTTVGEKPEEPKD 1364
A N G EP+ E ++T P+ P++
Sbjct: 7065 CARNKCGPGEPAYVDEPVNMSTPATVPDPPEN 7096
Score = 78.2 bits (191), Expect = 7e-14
Identities = 69/335 (20%), Positives = 137/335 (40%), Gaps = 41/335 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA ++L V ++ +L + D + I L K + F + + + ++
Sbjct: 22049 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHTKQLTFTV 22108
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
E+ + + ++ AKNDAG +E P+ + V+
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSE-------------------------PREAFSSVI--- 22140
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+K+ T + Q+I +AG + ++G TW +
Sbjct: 22141 ----IKEPQIEPTADLTGITNQLIT------CKAGSPFTIDVPISGRPAPKVTWKLEEMR 22190
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGT 1268
++E++ + + +++ + LT+ + + G Y L +EN G + V + V+ +P P G
Sbjct: 22191 LKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGP 22250
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSFNVQDLLP 1327
S + + S LSW GG+ + +Y +E +S W+ + ++ + T V L
Sbjct: 22251 IEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
EY FRV + N +G S+P + + + + E P P
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPI--IAEHPFVP 22343
Score = 77.0 bits (188), Expect = 2e-13
Identities = 81/346 (23%), Positives = 127/346 (36%), Gaps = 63/346 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P K V G+ L ++ +S P TI WT +G LK T I ++ L ++SI
Sbjct: 16733 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSI 16792
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y N GQ S ++ D P + K P
Sbjct: 16793 KETHKDDGGQYGITVANVVGQKTASIEIVTLDKP--DPPKGPV---------------KF 16835
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
D + + PP QI + ++ T W
Sbjct: 16836 DDVSAESITLSWNPPLYTGGCQITNYIVQKR----------------DTTTTVWDVVSAT 16879
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPD 1263
+ + +KV + G++ + + EN+ G A + +V +P
Sbjct: 16880 VARTT-LKVTKLKTGTEYQ-----------FRIFAENRYGQSFALESDPIVAQYPYKEPG 16927
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCR 1316
PP GTP A+ I S+ + W+ +GGS V Y +E +W NKT
Sbjct: 16928 PP-GTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKT-----IIH 16981
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
T F Q+L EY+FRV A N+ G + S+ SE + + P
Sbjct: 16982 DTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPP 17027
Score = 76.6 bits (187), Expect = 2e-13
Identities = 85/383 (22%), Positives = 150/383 (39%), Gaps = 47/383 (12%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L+D V E + CQ+S + A + W NG+ +K K ++GS+ + I+
Sbjct: 6328 FVEHLEDQTVTEFDDAVFSCQLSREK-ANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKD 6386
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQ-VTVD---------DAPASENTKAPEMKSRRP--- 1137
+D Y C ++ +A + + V+ +AP ++ E+ +
Sbjct: 6387 CRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQ 6446
Query: 1138 --KSSLPPVLGTESDAT-----------------------VKKKPAPKTPPKAAMPPQII 1172
++++ V G + + K + + A P+I
Sbjct: 6447 WLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAPKIK 6506
Query: 1173 QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAAR 1232
+D V G+ + + W K + + ++ + + IL A+
Sbjct: 6507 TADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT---IDTTAEQTSFRILEAK 6563
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGS 1292
+ G Y ++++NK G + +NL V+D P P ++ ++L+W DGGS
Sbjct: 6564 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLE-VTETFDGEVSLAWEEPLTDGGS 6622
Query: 1293 AVQSYSIEIWDSANKTWKELATCRSTS--FNVQDLLPDH-EYKFRVRAINVYGTSEPSQE 1349
+ Y +E D KTW LAT R+ S F V L EY FRV A N GT EP +
Sbjct: 6623 KIIGYVVERRDIKRKTW-VLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVET 6681
Query: 1350 SELTTVGEKPEEPKDEVEVSDDD 1372
K + P + V+ D
Sbjct: 6682 DNPVEARSKYDVPGPPLNVTITD 6704
Score = 76.3 bits (186), Expect = 3e-13
Identities = 43/138 (31%), Positives = 66/138 (47%), Gaps = 2/138 (1%)
Query: 1652 SSTGSPTSPLNAEKLESEE-DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1710
S TG+ E L E V++ E P P ++++ V+EG + +C
Sbjct: 859 SITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLEC 918
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
I GYP P V W+++D I S FQI + + G L+I + +D ++TC AVN G
Sbjct: 919 HISGYPSPTVTWYREDYQIESSIDFQITF-QSGIARLMIREAFAEDSGRFTCSAVNEAGT 977
Query: 1771 ATCTAELIVETMEEGEGE 1788
+ + L V+ EE E E
Sbjct: 978 VSTSCYLAVQVSEEFEKE 995
Score = 75.9 bits (185), Expect = 3e-13
Identities = 129/604 (21%), Positives = 220/604 (36%), Gaps = 74/604 (12%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
K P+ L D +G V +T ++ EV W + E F Q +
Sbjct: 4239 KEDGPMIHTPLVDTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTY 4296
Query: 610 SLCIQEVFPED-TGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 668
+L I +V ED G Y CEA N +G+ T A LTV + P K + +LG
Sbjct: 4297 TLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR---AAPVIKRKIEPLEVALGHL 4353
Query: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 728
+C I P W + G+ + ++ + ++ + +L + + Q G+Y
Sbjct: 4354 AKFTCEIQSAPNVRFQWFKAGREIY-ESDKCSIRSSKYISSLEILRTQVVDCGEYTCKAS 4412
Query: 729 NRVGECSCQVSLMLQ----NSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGW 784
N G SC +L + R L R+P E++ S+
Sbjct: 4413 NEYGSVSCTATLTVTVPGGEKKVRKLLPERKPEPKEEVV-------------LKSVLRKR 4459
Query: 785 PARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSED 844
P + +E + E V K+ + + + EV + R+ +K+ T +
Sbjct: 4460 PEEEEPKVEPKKLEKV----KKPAVPEPPPPKPVEEVEVPTVTKRE---RKIPEPTKVPE 4512
Query: 845 DLKEIPAEQMDFRANLQRQV---KPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEK 901
IP + + + +V KP V E + +P V V+ KK +K P E
Sbjct: 4513 IKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTV---PVVGKKAEAKAPKEEA 4569
Query: 902 VPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVE---SSKPLSNAQPSGPLKPVG 958
P P + G KK P+ + + E P + + PLK V
Sbjct: 4570 AKPKGP-------IKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVK 4622
Query: 959 NAKPAETLKP--MGNAKPAETLKPMGNA-----KPDENLKSASKEELKKDVKN------- 1004
K + +G++ E L A K N++ + K D K+
Sbjct: 4623 EIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIID 4682
Query: 1005 -------DVNC--KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSD 1055
+ C + G+ T K + K ++V V +G+ L L C+++ +
Sbjct: 4683 VQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKE 4742
Query: 1056 PPATIIWTLNGK-TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1114
++W +GK ++ I+ G + +++I A D G Y +N A ECS
Sbjct: 4743 --RDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVEN-ANNLECSS 4799
Query: 1115 QVTV 1118
V V
Sbjct: 4800 CVKV 4803
Score = 75.9 bits (185), Expect = 3e-13
Identities = 89/411 (21%), Positives = 156/411 (37%), Gaps = 69/411 (16%)
Query: 983 NAKPDENLKSASKEELKKDVKNDVNCKRGHA-GTTDNEKRSES-----QGTAPAFKQKLQ 1036
N++P ++LK +E + D + + + +A G ++ + SE+ P +
Sbjct: 7838 NSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETH 7897
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
D+ V EG+KL + + P T+ W +GK +K + + + + + + K++ D
Sbjct: 7898 DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADA 7957
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1156
G+Y +N G A S V V P ++K+ SD T
Sbjct: 7958 GIYTITLENKLGSATASINVKVIGLPGP----CKDIKA--------------SDITKSSC 7999
Query: 1157 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
PP+ G PI ++ R++ ++
Sbjct: 8000 KLTWEPPE---------------------------FDGGTPIL-HYVLERREAGRRTYIP 8031
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ--AQVNLTVVDKPDPPAGTPCASDI 1274
V + EN T+ + + NK+G + N + P P P ++
Sbjct: 8032 VMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEV 8091
Query: 1275 RS---SSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS-----TSFNVQDLL 1326
+ ++T++W YDGGS + Y IE + WK C ++ + L
Sbjct: 8092 HNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKR---CNEHLVPILTYTAKGLE 8148
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK----DEVEVSDDDE 1373
EY+FRVRA N G SEPS+ + T + + PK +EV DE
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDE 8199
Score = 73.9 bits (180), Expect = 1e-12
Identities = 82/367 (22%), Positives = 148/367 (40%), Gaps = 49/367 (13%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V+V G L + +S P + + +G LK T ++++++++ D G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG--TESDATVKK 1155
Y+ A N +G + + V D P P V+ TE T+K
Sbjct: 20049 RYEITAANSSGTTKAFINIVVLDRPGPPTG--------------PVVISDITEESVTLKW 20094
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P PK + + I+ ++ S ++ +V+ T + T MK K E+
Sbjct: 20095 EP-PKYDGGSQVTNYIL-------LKRETSTAVWTEVSAT--VARTMMKVMKLTTGEEYQ 20144
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIR 1275
+EN + + + S V L P PP+ TP +++
Sbjct: 20145 FRIKAEN-----------------RFGISDHIDSACVTVKLPYTT-PGPPS-TPWVTNVT 20185
Query: 1276 SSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKF 1333
S+T+ W+ +GGSAV Y +E+ D + W++ R+T F V + Y+F
Sbjct: 20186 RESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEF 20245
Query: 1334 RVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSD 1393
RV A N G +PS SE + E P++ V ++D + + ++ + K++
Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAIDACEPPRN-VRITDISKNSVSLSWQQPAFDGGSKITG 20304
Query: 1394 FYDIEER 1400
Y +E R
Sbjct: 20305 -YIVERR 20310
Score = 73.6 bits (179), Expect = 2e-12
Identities = 33/91 (36%), Positives = 56/91 (61%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P+F K ++ + +G A F+ + G P P V WFK+++ + S ++ I ++ +G+ + I
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++D +D Y CKA N LGE+TC AEL+V
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLV 3665
Score = 73.2 bits (178), Expect = 2e-12
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 12/174 (6%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVV 1259
R+++ ++ +++ G+ L + ++ + + EN+ G S + T +
Sbjct: 23770 RREVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL 23829
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRS 1317
+ P+PP+ P D+ SS++LSW DGGS V Y IE +++ W +
Sbjct: 23830 NPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITT 23889
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG---EKPEEPKDEVEV 1368
T + V L+PD EY+FR+ A N G SE S SE +KP +P E+E+
Sbjct: 23890 TMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQP-GELEI 23942
Score = 72.4 bits (176), Expect = 4e-12
Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 5/197 (2%)
Query: 1159 PKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
P+ PP + + ++ AG+++ + VTG T W K ++ + + + ++
Sbjct: 8601 PQEPPAVELD---VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRVVID 8656
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSS 1278
N S+L I A ++ G Y + N GS+ A + V D P P R
Sbjct: 8657 NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC 8716
Query: 1279 LTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAI 1338
L L+W DGGS + + IE D+ TW++ + ++ LL EYKFRV A
Sbjct: 8717 L-LNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 1339 NVYGTSEPSQESELTTV 1355
N +G P + + V
Sbjct: 8776 NKFGCGPPVEIGPILAV 8792
Score = 71.6 bits (174), Expect = 6e-12
Identities = 42/114 (36%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
+D P PPA A D SS+TL W YDGGSAV Y +EI + W ++T
Sbjct: 20667 IDPPGPPAKIRIA-DSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEV 20725
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
R+T + V +L P Y FRV A+N G EP + +E + E P+ +++V+
Sbjct: 20726 RTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVA 20779
Score = 71.2 bits (173), Expect = 8e-12
Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVN- 1255
P T W++ K + +V+ N K + +L EN G + +
Sbjct: 7427 PDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR-----------FRVLAENLAGPGKPSKST 7475
Query: 1256 --LTVVDKPDPP--AGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
+ + D DPP G P D+ +S+ L+W +DGG+ ++SY IE+ + W
Sbjct: 7476 EPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR 7535
Query: 1312 LAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEV 1368
+A +T + L+ EY FRVRA+N G SEPS+ S+ EK P P +EV
Sbjct: 7536 VAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEV 7595
Score = 70.9 bits (172), Expect = 1e-11
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 28/286 (9%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+ +VA + ++S+SV + V+++ P F+ +N+ IKEG+ + + R G P
Sbjct: 1480 GEWTVVAQNRAGRSSISVILT-VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPN 1538
Query: 62 PQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTV 119
P + W +N I + ++ G +G +L I + +D YT A N +G
Sbjct: 1539 PDIVWLKNSDIIVPHKYPKIRIE-GTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRC 1597
Query: 120 ELTVEGSFAKQLGQPVVSKTLG----DRFSAPAVETRPSIWG--------------ECPP 161
++ VE FA+ + + G +AP +E +G + P
Sbjct: 1598 KVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKP 1657
Query: 162 KFATKLGRVVVKEGQMGRFSCKIT--GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
F KL + +K F C++T G P V WL PL+ + R+ + + G L+
Sbjct: 1658 FFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLD 1717
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
D G+ TC N G SA L ++ +S V E++
Sbjct: 1718 YGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQ 1759
Score = 70.9 bits (172), Expect = 1e-11
Identities = 65/250 (26%), Positives = 97/250 (38%), Gaps = 23/250 (9%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
SE +GT P F +++ + ++ G L V P I W NG L + +G
Sbjct: 3450 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3509
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
S+ I ED G Y C+A ND G+ CS + + N+K K
Sbjct: 3510 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI-------NSKGEGHKD------- 3555
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
TE+++ V K P PP ++ + + G V G T T
Sbjct: 3556 -----TETESAVAKSLEKLGGP---CPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVT 3607
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTIL-AARQEHCGCYTLLVENKLGSRQAQVNLTVVD 1260
W K KQ+ S + + ++ NGS I+ ++E G Y EN LG L V+
Sbjct: 3608 WFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLL 3667
Query: 1261 KPDPPAGTPC 1270
+ TPC
Sbjct: 3668 EDTDMTDTPC 3677
Score = 70.9 bits (172), Expect = 1e-11
Identities = 92/386 (23%), Positives = 152/386 (39%), Gaps = 75/386 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V V G + L+ P +I W +G LK ++F+ S+ + ++SI+ A E G
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y + N C++ V P + T P K + P
Sbjct: 21136 KYTVILDNAV------CRIAV---PITVITLGPPSKPKGP-------------------- 21166
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKV---TGTQPITCTWMKFRKQIQESEH 1214
I+F E + +SV L V G ITC ++ R+ Q +
Sbjct: 21167 --------------IRFDEIK----ADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWK 21208
Query: 1215 MKVEN-SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGT 1268
M + + K+ L E+ + + EN+ G Q V+ +V K P PP G
Sbjct: 21209 MVCSSVARTTFKVPNLVKDAEYQ--FRVRAENRYGVSQPLVSSIIVAKHQFRIPGPP-GK 21265
Query: 1269 PCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTSFNVQDLL 1326
P ++ S ++L+W YDGGS V + +E + + W+++ T + L+
Sbjct: 21266 PVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLV 21325
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTIN 1386
+Y+FRV A N G S PS S+ T+ P +P + D V T+T+
Sbjct: 21326 EGLDYQFRVYAENSAGLSSPSDPSKF-TLAVSPVDPPGTPDYID-------VTRETITLK 21377
Query: 1387 TEQKVSD------FYDIEERLGSGKF 1406
+ D Y IE+R G+ ++
Sbjct: 21378 WNPPLRDGGSKIVGYSIEKRQGNERW 21403
Score = 70.5 bits (171), Expect = 1e-11
Identities = 79/335 (23%), Positives = 125/335 (37%), Gaps = 54/335 (16%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L + V G K+ L V+ P I WT LK K I + +V+I +
Sbjct: 7200 LAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRS 7259
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y A N G+A +V V D P PP +D T +
Sbjct: 7260 DTGTYIIEAVNVCGRATAVVEVNVLDKPG------------------PPAAFDITDVTNE 7301
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
PP+ +I + +++ E W K ++++
Sbjct: 7302 SCLLTWNPPRDDGGSKITNYVVERRATDSE----------------VWHKLSSTVKDTNF 7345
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTPC-- 1270
K T L +E+ + + EN G Q + +T + DPP G P
Sbjct: 7346 ----------KATKLIPNKEY--IFRVAAENMYGVGEPVQASPITAKYQFDPP-GPPTRL 7392
Query: 1271 -ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLP 1327
SDI ++TL+W DGGS + Y +E D W + T++ V+ L
Sbjct: 7393 EPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTN 7452
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+Y+FRV A N+ G +PS+ +E + + + P
Sbjct: 7453 KKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7487
Score = 70.1 bits (170), Expect = 2e-11
Identities = 39/94 (41%), Positives = 55/94 (58%), Gaps = 3/94 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR--HFQIDYDEDGNCS 1746
P F++ ++ + V+EGS A F+ I G+P PEV WF+D Q I S QI + DG
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISF-SDGRAK 64
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L I V + +Y+ KA N G+AT TAEL+V+
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 69.3 bits (168), Expect = 3e-11
Identities = 153/729 (20%), Positives = 270/729 (37%), Gaps = 101/729 (13%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVA 497
L V E+ F+ LKD V E + +C + T + W I+ +
Sbjct: 4982 LTVKEIELDFAVPLKDVTVPERRQARFECVL--TREANVIWSKGPDIIKSSDKFDIIADG 5039
Query: 498 ELHI---QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
+ HI D+ +D G YT E + S +VT K
Sbjct: 5040 KKHILVINDSQFDDEGVYTAEVEGK--KTSARLFVTGIRLK------------------- 5078
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F+ L D V +G T ++S + V+W N ++ S G H L ++
Sbjct: 5079 -FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMK 5136
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
EV +D + E+ + A L V E P+F K TA + + C
Sbjct: 5137 EVTLDDISQIKAQV----KELSSTAQLKVLE----ADPYFTVKLHDKTAVEKDEITLKCE 5188
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ D V W +DG+ + + + + L +KK G+Y C
Sbjct: 5189 VSKDV--PVKWFKDGEEIVPSP-KYSIKADGLRRILKIKKADLKDKGEYV---------C 5236
Query: 735 SCQVSLMLQNSSARA-LPRGREPASCEDLCGGGVG---ADGGGSDRYGSLRPGWPARGQG 790
C N + A L + +P ++ G + D +G W +GQ
Sbjct: 5237 DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQ----WKLKGQP 5292
Query: 791 WLEEEDGEDVRGVLKRRV--------ETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLS 842
D E + K + T + + +A + L ++L + LS
Sbjct: 5293 LTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKEL--PLIFITPLS 5350
Query: 843 EDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQV--DFRSVLAKKGTSKTPVPE 900
D+K ++ F + R+ PKT R + Q++ D R L K GT + V +
Sbjct: 5351 --DVKVFEKDEAKFECEVSRE--PKTF----RWLKGTQEITGDDRFELIKDGTKHSMVIK 5402
Query: 901 KVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
A F + + +G E + K + K ++ + + V +
Sbjct: 5403 SAAFEDEAKYMFEA------EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELS 5456
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
+K N + T + + + + + S + ++L D + + + G + K
Sbjct: 5457 HDNIRVKWFKNDQRLHTTRSV-SMQDEGKTHSITFKDLSIDDTSQIRVEA--MGMSSEAK 5513
Query: 1021 RSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE 1080
+ +G P F KLQD E +++LQC++S A + W +GK +K +K ++ +
Sbjct: 5514 LTVLEGD-PYFTGKLQDYTGVEKDEVILQCEISK-ADAPVKWFKDGKEIKPSKNAVIKAD 5571
Query: 1081 GSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSS 1140
G + ++KAL D G Y C D G + S ++ ++D E+K RP S
Sbjct: 5572 GKKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDR---------EIKLVRPLHS 5618
Query: 1141 LPPVLGTES 1149
+ V+ TE+
Sbjct: 5619 V-EVMETET 5626
Score = 69.3 bits (168), Expect = 3e-11
Identities = 94/414 (22%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 1148 ESDATVKKKP-----APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTW 1202
ESD V + P P TP A+ + + V G S + + + + W
Sbjct: 16913 ESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILW 16972
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
K K I K +N E G + + + EN +G +A N
Sbjct: 16973 TKVNKTIIHDTQFKAQNLEEGIEYE-----------FRVYAENIVGVGKASKNSECYVAR 17021
Query: 1263 DP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--ST 1318
DP P GTP ++ + +TL W YDGGS + Y +E D + W + + T
Sbjct: 17022 DPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIET 17081
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP--------KDEVEVS 1369
F V L D Y+FRV A N G S+PS + T ++ E P +D + V+
Sbjct: 17082 QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVN 17141
Query: 1370 DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFR--LVEKKTRKVWAGKF-F 1426
+ E D + T + + +IEE F+ L+ K ++ G++
Sbjct: 17142 AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 17201
Query: 1427 KAYSAKEKENIRQEISIMNCLHHPK-LVQCVDAFEEKANIVMVLEIVSGGELFERIIDED 1485
+A + ++ + +++ P+ VQ EK ++ + GG + E
Sbjct: 17202 RASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEK 17261
Query: 1486 FE-------LTERECIKYMRQIS---EGVEYIHKQGIVHLDLKPENIMCVNKTG 1529
E + E + +++ EG EY+ + IM VNK G
Sbjct: 17262 RETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFR------------IMAVNKYG 17303
Score = 69.3 bits (168), Expect = 3e-11
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVVDKPDP-----PAGTPCASDIRSSSLTLSWYGSSY 1288
GC Y + EN G ++ DP P P D +++T++W +
Sbjct: 19553 GCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLF 19612
Query: 1289 DGGSAVQSYSIEIWDSANKTWK-ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
DGG+ + Y++E S + WK + + R T + + L EY FRV+++N G S+PS
Sbjct: 19613 DGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPS 19672
Query: 1348 QESELTTVGEKPEEPKDEVE 1367
S+ E+ EEP +++
Sbjct: 19673 DSSDPQIAKEREEEPLFDID 19692
Score = 68.9 bits (167), Expect = 4e-11
Identities = 84/348 (24%), Positives = 127/348 (36%), Gaps = 66/348 (18%)
Query: 1029 PAFKQKLQDV-HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
P KL V V G + L+ V P + WT + T+ + +
Sbjct: 11704 PVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11763
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS-ENTKAPEMKSRRPKSSLPPV 1144
S+ KA D G Y A N AG V V D P N K ++ S R
Sbjct: 11764 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR-------- 11815
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
TV P P+ + I++ E +++ W
Sbjct: 11816 ------CTVCWDP-PEDDGGCEIQNYILEKCETKRM--------------------VWST 11848
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK--- 1261
+ + G+ +T L E+ + + ENK+G+ + V+ K
Sbjct: 11849 YSATVLTP----------GTTVTRLIEGNEYI--FRVRAENKIGTGPPTESKPVIAKTKY 11896
Query: 1262 -----PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
PDPP T + + +T+ W YDGG ++ Y +E + + W + +
Sbjct: 11897 DKPGRPDPPEVTKVSKE----EMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSA 11952
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
VQ+LLPDHEY+FRV+A N G EPS S V + P EP
Sbjct: 11953 IPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR-PVVAKDPIEP 11999
Score = 68.6 bits (166), Expect = 5e-11
Identities = 81/389 (20%), Positives = 141/389 (36%), Gaps = 63/389 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ + +V ++L + P AT+ W +G+TLK T + +S ++ S+SI
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSI 18957
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++A ED G Y+ N AG + V D P PP
Sbjct: 18958 KEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG------------------PPGPIRI 18999
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+ + PP+ QI + ++K + + TW +
Sbjct: 19000 DEVSCDSITISWNPPEYDGGCQISNYIVEKK----------------ETTSTTWHIVSQA 19043
Query: 1209 IQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----PDP 1264
+ + +K+ GS+ + + EN+ G + VV + P
Sbjct: 19044 VARTS-IKIVRLTTGSEYQ-----------FRVCAENRYGKSSYSESSAVVAEYPFSPPG 19091
Query: 1265 PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRS 1317
P GTP S++ ++W DGGS V Y +E +W ANK
Sbjct: 19092 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK-----ILIAD 19146
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPE 1377
T V L Y++RV A N+ G + S+ E P +P + EV++ K
Sbjct: 19147 TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE-PVPARDPCDPPGQPEVTNITRKSVS 19205
Query: 1378 VDYRTVTINTEQKVSDFYDIEERLGSGKF 1406
+ + + K++ + L G++
Sbjct: 19206 LKWSKPHYDGGAKITGYIVERRELPDGRW 19234
Score = 68.6 bits (166), Expect = 5e-11
Identities = 60/294 (20%), Positives = 118/294 (40%), Gaps = 57/294 (19%)
Query: 1022 SESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG 1081
S+ APAF + + ++ EG+ +L C++S +P I W N + + + +S+
Sbjct: 26630 SKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSR 26689
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------------- 1125
++ S+ I A D G Y AKN GQ + + V + P+ E
Sbjct: 26690 NVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQG 26749
Query: 1126 --NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA----------------- 1166
++++ +M + + ++S + + + + K A + +
Sbjct: 26750 SFSSQSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGI 26809
Query: 1167 --------------------MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
+PP+I P D + G+ + + TG TW
Sbjct: 26810 SNMTQLESSTSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869
Query: 1207 KQI--QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++I QE +EN+++ + L I+ +++ G YTL + N+ GS A VN+ +
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 67.8 bits (164), Expect = 9e-11
Identities = 72/265 (27%), Positives = 99/265 (37%), Gaps = 26/265 (9%)
Query: 389 LGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQE--VKENQTVKFR-CEGLAVMEVAP 445
L + V A+ + E Q +S P E + S E +E TVK + EG + E P
Sbjct: 4184 LDATPVTKGVASAVVSDEKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGP 4243
Query: 446 SFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQ 502
+ L D EG L S+ T + W + + + + + L I
Sbjct: 4244 MIHTPLVDTVSEEGDIVHLTTSI--TNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVID 4301
Query: 503 DALPEDH-GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
EDH G Y C A N G+ + SA +TV K AP+ + +
Sbjct: 4302 KVNTEDHQGEYVCEALNDSGKTATSAKLTV-----------------VKRAAPVIKRKIE 4344
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
L+V G T ++ P W G EI ES+ SL I D
Sbjct: 4345 PLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 4404
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEP 646
G YTC+A N G V A LTV P
Sbjct: 4405 GEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 67.4 bits (163), Expect = 1e-10
Identities = 42/117 (35%), Positives = 63/117 (53%), Gaps = 4/117 (3%)
Query: 1668 SEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
S + S A L AE P P F + ++ + V +GS R ++ G P P V +++D
Sbjct: 86 SGQATSTAELLVKAETAP---PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGA 142
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I+ S FQI + D SL+I++ +D Y+ A NS+G AT TAEL+V+ EE
Sbjct: 143 EIQSSLDFQISQEGD-LYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEE 198
Score = 67.4 bits (163), Expect = 1e-10
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 41/233 (17%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT---TKFIILSQEGSLCS 1085
P Q+LQ V V GK +S P I W + L T KF+ QE +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLL 3252
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ +A PED +Y C AKND G A S ++V+ PE+ S P +P
Sbjct: 3253 I---EAFPEDAAVYTCEAKNDYGVATTSASLSVE---------VPEVVS--PDQEMP--- 3295
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP II +D G+ +V+GT + +W
Sbjct: 3296 --------------------VYPPAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSK 3334
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
K+I+ S ++ E+ +L I A E G YT + N +G + NL++
Sbjct: 3335 DKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSL 3387
Score = 67.0 bits (162), Expect = 2e-10
Identities = 78/330 (23%), Positives = 117/330 (35%), Gaps = 66/330 (20%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
++ + V G + + P T WT +G +KT + + + ++I+ L
Sbjct: 11020 IEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRR 11079
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y+ N AG + +TV D P P + + T T+
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTVLDVPGP------------PTGPINILDVTPEHMTIS 11127
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P P I E Q R + +G V+
Sbjct: 11128 WQP----PKDDGGSPVINYIVEKQDTRK----DTWGVVS--------------------- 11158
Query: 1215 MKVENSENGSKLTILAARQEHCGC---YTLLVENKLGSRQAQVNLTVVDK----PDPPAG 1267
+GS T L GC + + ENK+G + V K P P G
Sbjct: 11159 -------SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPG 11211
Query: 1268 TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI------WDSANKTWKELATCRSTSFN 1321
P +DI ++ T+SW DGGS + Y +E W NKT F
Sbjct: 11212 KPVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKT-----PIADLKFR 11266
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
V L + Y+FRV A N+ G S+PS S+
Sbjct: 11267 VTGLYEGNTYEFRVFAENLAGLSKPSPSSD 11296
Score = 67.0 bits (162), Expect = 2e-10
Identities = 76/322 (23%), Positives = 120/322 (37%), Gaps = 60/322 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + L V P T+ W +G LK + I ++ + +LC++ + +D G Y
Sbjct: 12810 VKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDY 12869
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASE-NTKAPEMKSRRPKSSLPPVL---GTESDATVKK 1155
A+N +G + ++ V D P + K +M S R S P L G+E +
Sbjct: 12870 TITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD 12929
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
K P A +V+ T PIT ++ K I+ E+
Sbjct: 12930 KRETSRPNWA-------------------------QVSATVPITSCSVE--KLIEGHEYQ 12962
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPA--GTPCA 1271
+ + ENK G + K DPP P
Sbjct: 12963 -----------------------FRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVI 12999
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
S+I +T+SW + DGGS + Y +E ++ W ++ + L
Sbjct: 13000 SNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGT 13059
Query: 1330 EYKFRVRAINVYGTSEPSQESE 1351
EY+FRV AIN G +PS S+
Sbjct: 13060 EYEFRVTAINKAGPGKPSDASK 13081
Score = 66.6 bits (161), Expect = 2e-10
Identities = 82/367 (22%), Positives = 139/367 (37%), Gaps = 64/367 (17%)
Query: 1014 GTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--------SDPPATIIWTLN 1065
G +D S+ Q ++ L D+ K L+++ S P ++W+
Sbjct: 19667 GASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKP 19726
Query: 1066 GKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
L+T ++ + S S++IE A D G Y +N A + V V D P
Sbjct: 19727 DTDLRTRAYVDTTD--SRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPG-- 19782
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGES 1185
PP T D T + A + + PE+
Sbjct: 19783 ----------------PPTNITVQDVTKES---------AVLSWDV---PEND------- 19807
Query: 1186 VELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV-- 1243
G P+ ++ R + S+ V + N ++L+ + Y V
Sbjct: 19808 --------GGAPVKNYHIEKR---EASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSG 19856
Query: 1244 ENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE 1300
EN+ G + + + + +KP PP S I S++L+W +DGGS + Y +E
Sbjct: 19857 ENEFGVGIPAETKEGVKITEKPSPPEKLGVTS-ISKDSVSLTWLKPEHDGGSRIVHYVVE 19915
Query: 1301 IWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1360
+ K W + A +ST V L + EY FRV A N G S+P + + E+ E
Sbjct: 19916 ALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLE 19975
Query: 1361 EPKDEVE 1367
P+ +++
Sbjct: 19976 PPEIDMK 19982
Score = 65.9 bits (159), Expect = 3e-10
Identities = 79/316 (25%), Positives = 128/316 (40%), Gaps = 54/316 (17%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ + GK L + V+ P T +WT L + +++ G+ + I+ AL +D G
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR-VVIDNVGTKSELIIKDALRKDHG 8675
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y A N G + +V V D P P L PV+ T +
Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPG-------------PVLDLKPVV-TNRKMCLLNWS 8721
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
P+ + + II+ +D K+ T QPI E+E K
Sbjct: 8722 DPEDDGGSEITGFIIE-RKDAKMH-----------TWRQPI------------ETERSKC 8757
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVN-LTVVDKPDPPAGTP--CASD 1273
+ +T L QE+ + ++ +NK G ++ + VD PP ++
Sbjct: 8758 D-------ITGLLEGQEYK--FRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTE 8808
Query: 1274 IRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEY 1331
S++TL W +GGS +Q Y IE ++ + C +TSF V++L Y
Sbjct: 8809 RTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMY 8868
Query: 1332 KFRVRAINVYGTSEPS 1347
+FRV+A+N G SEPS
Sbjct: 8869 EFRVKAVNEIGESEPS 8884
Score = 65.9 bits (159), Expect = 3e-10
Identities = 74/315 (23%), Positives = 115/315 (36%), Gaps = 53/315 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G+ L+ VS PP T+ W+ +GK L+ T + + ++ + + D G Y
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A N G A+ V V D P P V S+ V P
Sbjct: 15039 ATNPGGFAKHIFNVKVLDRPG-------------PPEGPLAVTEVTSEKCVLSWFPPLDD 15085
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I+Q E ++ W ++Q ++
Sbjct: 15086 GGAKIDHYIVQKRETSRL--------------------AWTNVASEVQVTK--------- 15116
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKPDPPAGTPCASDIRSS 1277
K+T L E+ + ++ NK G + + V+ PDPP P + I
Sbjct: 15117 -LKVTKLLKGNEYI--FRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKN-PEVTTITKD 15172
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+ + W DGGS + +Y +E D A + W + T + V L HEY+FR+
Sbjct: 15173 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15232
Query: 1336 RAINVYGTSEPSQES 1350
A N G S PS S
Sbjct: 15233 MAENAAGISAPSPTS 15247
Score = 65.9 bits (159), Expect = 3e-10
Identities = 40/122 (32%), Positives = 60/122 (49%), Gaps = 5/122 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y +L EN+ G + ++ ++P PP G D+ +S++LSW +
Sbjct: 15519 QEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPP-GKITLMDVTRNSVSLSWEKPEH 15577
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
DGGS + Y +E+ + W AT + T + L+ EY FRV A N G S+P Q
Sbjct: 15578 DGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQ 15637
Query: 1349 ES 1350
S
Sbjct: 15638 LS 15639
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 6/116 (5%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PP+ P D S++L+W YDGG+ + Y +E+ + W + AT R+T
Sbjct: 22845 PGPPSA-PRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNT 22903
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
F V DL +Y FRV A+NV G SE S+ E+ E P ++E++DD +K
Sbjct: 22904 EFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP--DLELADDLKK 22957
Score = 65.5 bits (158), Expect = 5e-10
Identities = 84/382 (21%), Positives = 154/382 (40%), Gaps = 28/382 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R GRP P++TW + + +V + + L I +++D G
Sbjct: 17537 IVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLSIDNCDRNDAG 17594
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLE 289
Y + N SG S SA ++++ LD+ K +VRK+ ++ + +D
Sbjct: 17595 KYILKLENSSG--SKSAFVTVKVLDTPGPPQNLAVK----EVRKDSAFLVWEPPIIDG-- 17646
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRES-KLESCKDSPRTAPQTPVLQKTSSSI--- 345
AK KN +R + AN + + S K+E+ + + + +
Sbjct: 17647 -GAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVE 17705
Query: 346 TLQAARVQPEPRAPGLGVLSPSG--------EERKRPAPPRPATFPTRQPGLGSQ--DVV 395
T+ A + P PG L+ E+ + R + G++ +V
Sbjct: 17706 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17765
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
+++ + G +F K +++ K + V + + PS +
Sbjct: 17766 AESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYS 17825
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALPEDHGTY 512
+ G+D ++ V G P P I+W+ +G+P+ Q R E A LHI++ +D G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885
Query: 513 TCLAENALGQVSCSAWVTVHEK 534
T A N+ G + + V V EK
Sbjct: 17886 TVTATNSAGTATENLSVIVLEK 17907
Score = 65.5 bits (158), Expect = 5e-10
Identities = 62/258 (24%), Positives = 96/258 (37%), Gaps = 37/258 (14%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG-RFLLDCGIRGTF 89
+AP F RNL ++ + A +V G+P+P V W+R G+ I + G ++ + G
Sbjct: 24429 QAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYH 24488
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAV 149
L+I +V ++D Y ATN G+ T L VE L
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHL------------------ 24530
Query: 150 ETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV 209
PK +G V G++ +G+P P +TW KG + + V
Sbjct: 24531 -----------PKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHYQV 24579
Query: 210 SEKNGMQVLEI-HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATN 268
L +GV + D G Y N G + EL + + R
Sbjct: 24580 IVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRG------VKV 24633
Query: 269 SDVRKEVTNVISKESKLD 286
SDV ++ N+ E D
Sbjct: 24634 SDVSRDSVNLTWTEPASD 24651
Score = 64.7 bits (156), Expect = 8e-10
Identities = 71/342 (20%), Positives = 124/342 (36%), Gaps = 55/342 (16%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ K + G+ L ++ V P I W +G+ LK T + + + + + I
Sbjct: 17815 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHI 17874
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
++ +D G Y A N AG A + V V + P PPV
Sbjct: 17875 KEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG------------------PPVGPVR 17916
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D + PP QI + +++ T TW
Sbjct: 17917 FDEVSADFVVISWEPPAYTGGCQISNYIVEKR----------------DTTTTTWHMVSA 17960
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV-----DKP 1262
+ + +K+ + G++ + + EN+ G + V+ +P
Sbjct: 17961 TVARTT-IKITKLKTGTEYQ-----------FRIFAENRYGKSAPLDSKAVIVQYPFKEP 18008
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSF 1320
PP GTP + I + + W+ DGG+ + Y +E + + W +L + T F
Sbjct: 18009 GPP-GTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKF 18067
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
L EY+F+V A N+ G +PS+ SE + + P
Sbjct: 18068 KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPP 18109
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/307 (21%), Positives = 118/307 (38%), Gaps = 39/307 (12%)
Query: 9 SSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR 68
S+ + + SL + S + T A + PR++ + EG +A+F G P P VTW R
Sbjct: 26041 SAALEEKSLE-EKSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLR 26099
Query: 69 NGQPITSGGRF-LLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS- 126
GQ +++ R + + TF I +V D G Y+ N G ++ LT++ +
Sbjct: 26100 KGQVLSTSARHQVTTTKYKSTFE--ISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKAR 26157
Query: 127 -FAKQLGQPVVSKTLGDRFSAP---------------------AVETRPS-------IWG 157
K + P K+ R +P ET+P+ +
Sbjct: 26158 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 26217
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGR--PQPQVTWLKGNVPLQPSARVSVS-EKNG 214
PPK L KE + + +C + +VTW K L+ + +G
Sbjct: 26218 SAPPKITQFLKAEASKE--IAKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADG 26275
Query: 215 MQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
L+I+ + + D G Y C + G + + + Q S + + ++ SD +
Sbjct: 26276 TYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKSDQKTT 26335
Query: 275 VTNVISK 281
+ V K
Sbjct: 26336 ESTVTRK 26342
Score = 64.3 bits (155), Expect = 1e-09
Identities = 46/189 (24%), Positives = 86/189 (45%), Gaps = 6/189 (3%)
Query: 1180 VRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCY 1239
VR G+++ + +V G TW K K + + + + +L I A + G Y
Sbjct: 11423 VRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKY 11482
Query: 1240 TLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
+ +N G Q + V+D+P P +++ + T+SW +GGS + ++ +
Sbjct: 11483 IISAKNSSGHAQGSAIVNVLDRPGPCQNLK-VTNVTKENCTISWENPLDNGGSEITNFIV 11541
Query: 1300 EIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG--- 1356
E K W +A+ + +LL ++EY FRV A N G P+ E++ +
Sbjct: 11542 EYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG-PTIETKTPILAINP 11600
Query: 1357 -EKPEEPKD 1364
++P EP++
Sbjct: 11601 IDRPGEPEN 11609
Score = 64.3 bits (155), Expect = 1e-09
Identities = 66/229 (28%), Positives = 97/229 (42%), Gaps = 25/229 (10%)
Query: 1146 GTESDATVKKKP--APKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITC 1200
G +S+ V + P P PP PP I+ D SV L K TG PIT
Sbjct: 13664 GLKSEPIVARHPFDVPDAPP----PPNIVDVRHD-------SVSLTWTDPKKTGGSPITG 13712
Query: 1201 TWMKF--RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
++F R + K K+T L E+ + ++ N G + +
Sbjct: 13713 YHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE--FRVMAINLAGVGKPSLPSEP 13770
Query: 1259 VDKPDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--AT 1314
V DP P G P +I +S+TL W YDGG + Y +E D +K+W +
Sbjct: 13771 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVN 13830
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEP 1362
+F V DL+ +Y+FR+RA N G S PS+ +E ++ E P
Sbjct: 13831 VPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/118 (33%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 1233 QEHCGCY-TLLVENKLG---SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY 1288
QE C Y + EN+ G Q + V + P PP G D+ +S++LSW +
Sbjct: 16601 QEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPP-GKITVDDVTRNSVSLSWTKPEH 16659
Query: 1289 DGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
DGGS + Y +E+ ++ W E A +S + +L EY FRV A+N G S+P
Sbjct: 16660 DGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDP 16717
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/224 (25%), Positives = 89/224 (39%), Gaps = 19/224 (8%)
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTG-----TQPITCTW 1202
S+ TV + P K P P + + +V+ E + G +V G + + W
Sbjct: 15832 SEPTVAQYPF-KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW 15890
Query: 1203 MKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+K K K E G + + + G +G V P
Sbjct: 15891 VKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVG---------IGKPSKVSECYVARDP 15941
Query: 1263 DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCR--STSF 1320
P G P A + +S+TL W +YDGGS + Y +E + W + + T F
Sbjct: 15942 CDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHF 16001
Query: 1321 NVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPK 1363
V L+ DH Y+FRV A N G SEPS+ + T ++ + P+
Sbjct: 16002 EVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPR 16045
Score = 63.5 bits (153), Expect = 2e-09
Identities = 78/337 (23%), Positives = 129/337 (38%), Gaps = 55/337 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L+ +S P TI W + K L+T + + L S+ I+ A + G Y+
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELK 20449
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G A + +V + D P P + T T+ +P P
Sbjct: 20450 LRNAMGSASATIRVQILDKPGP------------PGGPIEFKTVTAEKITLLWRP-PADD 20496
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
A + I++ E +V W SEH++ E
Sbjct: 20497 GGAKITHYIVEKRETSRV--------------------VWSMV------SEHLE----EC 20526
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
T + E+ + + NK G + + +VV K P PP G P + I +
Sbjct: 20527 IITTTKIIKGNEYI--FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPP-GIPEVTKITKN 20583
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHEYKFRV 1335
S+T+ W DGGS + Y +E D + W ++ T R T V L + +Y++RV
Sbjct: 20584 SMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643
Query: 1336 RAINVYGTSEPSQESELTTVGE--KPEEPKDEVEVSD 1370
A+N G S+ SE + P P ++ ++D
Sbjct: 20644 CAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20680
Score = 63.2 bits (152), Expect = 2e-09
Identities = 33/95 (34%), Positives = 48/95 (50%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P + I+ V +GS A F ++ G PDPE W+K+ I S + ED C L+
Sbjct: 2032 PKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELV 2091
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
I DV +D A KA+N GE + A L+V+ +
Sbjct: 2092 IRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQ 2126
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE-------LAT 1314
P P P D SS++L W + DGGS ++ Y +E+ + WK + T
Sbjct: 9207 PPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITT 9266
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
C N+++L +Y+FRV+A+N G SEPS + + EEP+ +++ D
Sbjct: 9267 CECVVPNLKEL---RKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQD 9321
Score = 63.2 bits (152), Expect = 2e-09
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL----AT 1314
+ KP PP P A D +S+ L+W +DGGS + Y +E ++ W+ +
Sbjct: 10613 IAKPSPPVN-PEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPES 10671
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPK 1363
C T + V L YKFRV A+N G S+P+ E V ++ E P+
Sbjct: 10672 CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPE 10720
Score = 63.2 bits (152), Expect = 2e-09
Identities = 110/471 (23%), Positives = 168/471 (35%), Gaps = 95/471 (20%)
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSAS 994
K V +S PLS P L+ K + TL L P+ G AK D + S
Sbjct: 12291 KPVLASDPLSEPDPPRKLEVTEMTKNSATLA---------WLPPLRDGGAKIDGYITSYR 12341
Query: 995 KEELKKDVKNDVNCKRGHA----GTTDNEKRS---------------ESQGTAPAFKQKL 1035
+EE D + + + + G + +K E++G A +Q L
Sbjct: 12342 EEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLL 12401
Query: 1036 -------QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
+ + + GKKL ++ V P T W + T+ + + + S + I
Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILII 12461
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPP--VLG 1146
+ +D G Y A+N +G +V V DAP PP +
Sbjct: 12462 KDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ---------------PPFDISD 12506
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
++DA P + + I+ E V G+ V VT T +
Sbjct: 12507 IDADACSLSWHIPLEDGGSNITNYIV---EKCDVSRGDWVTALASVTKTS------CRVG 12557
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPA 1266
K I E++ +EN G L K+ AQ V +P
Sbjct: 12558 KLIPGQEYIFRVRAEN------------RFGISEPLTSPKM---VAQFPFGVPSEPKNAR 12602
Query: 1267 GTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTS 1319
T D + ++W DGGS + Y IE +W AN T RST
Sbjct: 12603 VTKVNKDC----IFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDT-----LVRSTE 12653
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
+ L+ EY FR+ A+N G+S PS+ +E T P +P + EV D
Sbjct: 12654 YPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVT-ARMPVDPPGKPEVID 12703
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/210 (24%), Positives = 91/210 (43%), Gaps = 11/210 (5%)
Query: 45 KEGATAKFEGRVRGYPEP-QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+EG K+ ++ Y + QVTW+ + + + ++ + G L + + + D G
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYE-DGVAILYVKDITKLDDGT 25141
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKF 163
Y C+ N G EL V+G +++ +T+ + +T + E PP+F
Sbjct: 25142 YRCKVVNDYGEDSSYAELFVKG--VREVYDYYCRRTM--KKIKRRTDTMRLL--ERPPEF 25195
Query: 164 ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP---SARVSVSEKNGMQVLEI 220
L G+ RF IT P+P VTW K ++P + + G+ L I
Sbjct: 25196 TLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTI 25255
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ V DD YT + N G+ S A+L++
Sbjct: 25256 NSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/249 (23%), Positives = 97/249 (38%), Gaps = 12/249 (4%)
Query: 1017 DNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVS--SDPPATIIWTLNGKTLKTTKF 1074
D EK+ + P FK+KL + + +C+++ DP + W +GK L+
Sbjct: 1650 DKEKQQK-----PFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANR 1704
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKS 1134
+ + E CS+ A D G+ C A N G S + V D E + E +
Sbjct: 1705 LRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKD----EKSLVEESQL 1760
Query: 1135 RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTG 1194
+ L + E A T K P I+ +PE +V GE+ +VTG
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1195 TQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQV 1254
W + I++S+ +V + L I+ + G + EN G + +V
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHKV 1879
Query: 1255 NLTVVDKPD 1263
L + + D
Sbjct: 1880 KLEIQQRED 1888
Score = 62.8 bits (151), Expect = 3e-09
Identities = 40/111 (36%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRS 1317
KP PP P DI SS+ LSW YDGG +Q Y +E D + W
Sbjct: 16340 KPGPP-NNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINK 16398
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
T+ V+ LL HEY FR+ AIN G E + V EK E P ++++
Sbjct: 16399 TNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDL 16449
Score = 62.4 bits (150), Expect = 4e-09
Identities = 61/234 (26%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELH 500
AP +KD G+ L C + G P+P I W G+ + +R + + L
Sbjct: 24035 APGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLT 24094
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQG 559
+ ED G YTC+A N +G+V S S+ LL P P P+ +
Sbjct: 24095 VMTEEQEDEGVYTCIATNEVGEVETS-------------SKLLLQATPQFHPGYPLKEKY 24141
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
+ GS + + V G P P + W H +Q SE+ E L ++ V +
Sbjct: 24142 YGAV----GSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRK 24197
Query: 620 -DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
G Y + N G V A+L V+ +P + P + A L S +IS
Sbjct: 24198 THAGKYKVQLSNVFGTV--DAILDVEIQDKPDKP---TGPIVIEALLKNSAVIS 24246
Score = 62.0 bits (149), Expect = 5e-09
Identities = 43/152 (28%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PP + L V V EG+ C I+G P P VTW + + ++ S ++ ++G+ L
Sbjct: 896 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 955
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I +D G +TC VN +G S S L++Q + F +ET A VT
Sbjct: 956 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ----VSEEFEKETTA--------VTEKF 1003
Query: 280 SKESK--LDSLEAAAKSKNCSSPQRGGSPPWA 309
+ E K ++S + + + Q G P A
Sbjct: 1004 TTEEKRFVESRDVVMTDTSLTEEQAGPGEPAA 1035
Score = 62.0 bits (149), Expect = 5e-09
Identities = 42/168 (25%), Positives = 71/168 (42%), Gaps = 12/168 (7%)
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-----SRQAQVNLTVVD 1260
+++ + V + TI + H + ++ +NK G + + +
Sbjct: 9759 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL------AT 1314
P P P S + +S+T++W YDGGS V Y +E+ D+ +K WK + A
Sbjct: 9819 VPGAP-DKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAM 9877
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
S+ V L+ +Y+FRV AIN G S S+ T + P
Sbjct: 9878 TLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPP 9925
Score = 62.0 bits (149), Expect = 5e-09
Identities = 77/340 (22%), Positives = 133/340 (39%), Gaps = 57/340 (16%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+ V G+ + + +V P I WT GK L K + L Q+ + I++A+ D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKP 1157
Y AKN +G A+ S V V D P P +L T+ + T+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNVLDRPG-------------PCQNLKVTNVTKENCTIS--- 11524
Query: 1158 APKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKV 1217
+ P D G IT +++RK Q+ +
Sbjct: 11525 --------------WENPLD---------------NGGSEITNFIVEYRKPNQKGWSIVA 11555
Query: 1218 ENSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCA 1271
+ L A E+ + + ENK+G ++ + + +D+P P A
Sbjct: 11556 SDVTKRLIKANLLANNEY--YFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIA 11613
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDH 1329
D + + L W YDGGS SY +E + W+ + + + T + V + +
Sbjct: 11614 -DKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQ 11672
Query: 1330 EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
Y+FRV+ N G S+ + E+ V E ++P ++++S
Sbjct: 11673 IYEFRVQTKNEGGESDWVKTEEV-VVKEDLQKPVLDLKLS 11711
Score = 61.6 bits (148), Expect = 7e-09
Identities = 48/182 (26%), Positives = 83/182 (45%), Gaps = 25/182 (13%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF 1074
T+ E +++ P F Q+LQ + V +G ++ LQ +V+ P + + +G ++++
Sbjct: 90 TSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD 149
Query: 1075 IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE------ 1125
+SQEG L S+ I +A PED G Y A N G+A + ++ V ++ PA +
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS 209
Query: 1126 NTKAPEMKSRRPKSSLPPVLGTESDATVK------------KKPAPKTPPK----AAMPP 1169
+ E + R + + S ATV+ K P+ PPK + PP
Sbjct: 210 TAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPP 269
Query: 1170 QI 1171
I
Sbjct: 270 SI 271
Score = 61.6 bits (148), Expect = 7e-09
Identities = 35/96 (36%), Positives = 46/96 (47%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
KP F + +EG ARFD K+ G P PE WF D Q I ++ EDG SL
Sbjct: 1410 KPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSL 1469
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
II D ++T A N G ++ + L VE +E
Sbjct: 1470 IIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVE 1505
Score = 61.6 bits (148), Expect = 7e-09
Identities = 44/140 (31%), Positives = 62/140 (44%), Gaps = 7/140 (5%)
Query: 1239 YTLLVENKLGSRQAQVN---LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQ 1295
+ ++ EN G + + +D DPP G P +I ++TL W Y GG +
Sbjct: 14834 FRVIAENMAGKSKPSKPSEPMLALDPIDPP-GKPVPLNITRHTVTLKWAKPEYTGGFKIT 14892
Query: 1296 SYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQESEL 1352
SY +E D N W + F V L D Y+FRV A N G S PS+ S+
Sbjct: 14893 SYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDA 14952
Query: 1353 TTVGEKPEEPKDEVEVSDDD 1372
T + E PK +V+V D
Sbjct: 14953 ITCRDDVEAPKIKVDVKFKD 14972
Score = 61.6 bits (148), Expect = 7e-09
Identities = 91/388 (23%), Positives = 134/388 (34%), Gaps = 60/388 (15%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PAFK V G+ L + P + W + LK T + + ++I
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTI 15710
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A ED G Y N AG+A + V V D P PP +
Sbjct: 15711 KDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG------------------PPTGPVK 15752
Query: 1149 SD-ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
D T PP K G S+ + V T TW
Sbjct: 15753 MDEVTADSITLSWGPP---------------KYDGGSSINNY-IVEKRDTSTTTWQIV-- 15794
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGC---YTLLVENKLG-SRQAQVNLTVVDKP- 1262
S ++ TI A R + GC + + EN+ G S TV P
Sbjct: 15795 ------------SATVARTTIKACRLK-TGCEYQFRIAAENRYGKSTYLNSEPTVAQYPF 15841
Query: 1263 --DPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRST 1318
P GTP + S+ + W DGGS V Y +E + + W +L T
Sbjct: 15842 KVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQT 15901
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F L EY+FRV A N+ G +PS+ SE V P +P E +
Sbjct: 15902 KFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSE-CYVARDPCDPPGRPEAIIVTRNSVTL 15960
Query: 1379 DYRTVTINTEQKVSDFYDIEERLGSGKF 1406
++ T + K++ + ++ L G++
Sbjct: 15961 QWKKPTYDGGSKITGYIVEKKELPEGRW 15988
Score = 61.6 bits (148), Expect = 7e-09
Identities = 82/331 (24%), Positives = 122/331 (36%), Gaps = 60/331 (18%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P +K + VH E K+ + P TI W + L T + + S+S+
Sbjct: 16050 PKYKDTIV-VHAGESFKV--DADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16106
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTE 1148
+ A+ D G Y AKN AG+ + V V D P PE P V+
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGP-----PEG---------PVVI--- 16149
Query: 1149 SDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVT--GTQPITCTWMKFR 1206
S T +K PP II + +++ E+ L V Q ++C
Sbjct: 16150 SGVTAEKCTLAWKPPLQDGGSDIINYIVERR----ETSRLVWTVVDANVQTLSC------ 16199
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK----- 1261
KV G++ T + ++ NK G + + VV K
Sbjct: 16200 ---------KVTKLLEGNEYT-----------FRIMAVNKYGVGEPLESEPVVAKNPFVV 16239
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTS 1319
PD P P + + S+ + W + DGGS + Y +E D W
Sbjct: 16240 PDAPKA-PEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELR 16298
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
V L+ +H+Y+FRV A N G SEPS S
Sbjct: 16299 LRVTGLIENHDYEFRVSAENAAGLSEPSPPS 16329
Score = 61.6 bits (148), Expect = 7e-09
Identities = 45/169 (26%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W+K K + K + G + + + G +G V
Sbjct: 18054 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVG---------IGKPSKVSECFVARD 18104
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTS 1319
P P G P A I +++TL W +YDGGS + Y +E D + W + T
Sbjct: 18105 PCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETE 18164
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
F V L+ D Y+FRV A N G SEPS S T ++ + P ++
Sbjct: 18165 FTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLD 18213
Score = 61.6 bits (148), Expect = 7e-09
Identities = 43/134 (32%), Positives = 63/134 (47%), Gaps = 9/134 (6%)
Query: 1252 AQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE 1311
AQ+ TV D P G P S+I +S+TL+W DGGS +Q Y +E + + W +
Sbjct: 21648 AQIQYTVPDAP----GIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVK 21703
Query: 1312 LATCR---STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE--KPEEPKDEV 1366
+ + R T F V L +EY+F V A N G S S L E P P V
Sbjct: 21704 VISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVV 21763
Query: 1367 EVSDDDEKEPEVDY 1380
+V+D + +++
Sbjct: 21764 KVTDTSKTTVSLEW 21777
Score = 61.2 bits (147), Expect = 9e-09
Identities = 36/112 (32%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P P P +D SS++L+W YDGG+ V+ Y +E+ ++A W TC
Sbjct: 18505 PPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEW---TTCTPPTGL 18561
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
+ F V L + EY FR+ AIN G EP+ E+ E P+ E++
Sbjct: 18562 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELD 18613
Score = 61.2 bits (147), Expect = 9e-09
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 65/342 (19%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+HV G+ + L ++ PP W G L+ ++ + + + ++I + D G
Sbjct: 23251 IHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTG 23310
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT---VK 1154
Y KN G + +V + D P P+ E DAT +
Sbjct: 23311 EYTLELKNVTGTTSETIKVIILDKPGPPTG---------------PIKIDEIDATSITIS 23355
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
+P P+ A + +++ + + G + ++ +T + KF + + +E+
Sbjct: 23356 WEP-PELDGGAPLSGYVVEQRDAHRP---------GWLPVSESVTRSTFKFTRLTEGNEY 23405
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
+ + A + G Y +++++ ++ + + P PP T D+
Sbjct: 23406 V----------FRVAATNRFGIGSY---LQSEVIECRSSIRI-----PGPPE-TLQIFDV 23446
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE-------IWDSANKTWKELATCRSTSFNVQDLLP 1327
+TL+WY DGGS V Y +E W NK + RST L
Sbjct: 23447 SRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTG-----LTE 23501
Query: 1328 DHEYKFRVRAINVYGTSEPSQESELTTVGE------KPEEPK 1363
EY+ RV AIN G+ +PS+ S+ + KP+ P+
Sbjct: 23502 GLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPR 23543
Score = 60.8 bits (146), Expect = 1e-08
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 2/112 (1%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
+E P P ++D EG ARF C++ G D +V W+ D+ I+ SR F++ E
Sbjct: 3292 QEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG-TDLKVSWYSKDKKIKPSRFFRMTQFE 3350
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
D L I++ +D+ YT A N++G+ + TA L +E E E E+E
Sbjct: 3351 D-TYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQE 3401
Score = 60.5 bits (145), Expect = 1e-08
Identities = 34/89 (38%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRST 1318
P PPA P D SS++LSW +YDGGS + Y +E+ + + W + T
Sbjct: 13092 PGPPA-FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKT 13150
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
F V L+ D +Y+FRV A+N G S+PS
Sbjct: 13151 RFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179
Score = 60.5 bits (145), Expect = 1e-08
Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)
Query: 1256 LTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
+ ++P PP D SS L+W +DGGS + Y +E+ + W E
Sbjct: 22043 IVATEQPAPPRRLDVV-DTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT 22101
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
+ +F V+ L+ EY+FRV+A N G SEP + + E EP
Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22148
Score = 60.5 bits (145), Expect = 1e-08
Identities = 29/97 (29%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
P++ P + ++ + + AKF + G P P W ++G+ IT GG++ L +G
Sbjct: 26350 PISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLS-EDKG 26408
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
F L IH D G YTC N +G+ + +LT++
Sbjct: 26409 GFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 26445
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATC 1315
V KP PP G P D SS++++W YDGGS + Y +EI W+ + A
Sbjct: 15256 VFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGL 15314
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
++TS+ + L + EYK R+ A+N G EP+
Sbjct: 15315 KATSYTITGLTENQEYKIRIYAMNSEGLGEPA 15346
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 16/176 (9%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
W K K + MKV + G Y + EN G + + V
Sbjct: 19136 WSKANKILIADTQMKVSGLDEGLMYE-----------YRVYAENIAGIGKCSKSCEPVPA 19184
Query: 1262 PDP--PAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRS 1317
DP P G P ++I S++L W YDGG+ + Y +E + + W + +
Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE 19244
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVY-GTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
T F V +L D Y+FRV A N SEPS+ + V + E P+ ++V D
Sbjct: 19245 TYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRD 19300
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/318 (23%), Positives = 124/318 (38%), Gaps = 51/318 (16%)
Query: 430 TVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR 489
T K EG V F L+D V E L+C V + W N ++
Sbjct: 2211 TAKLIVEGAVV-----EFVKELQDIEVPESYSGELECIVSPENIEG-KWYHNDVELKSNG 2264
Query: 490 S---TCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPV 546
T G L ++D ED G Y+ + + KK++ K +
Sbjct: 2265 KYTITSRRGRQNLTVKDVTKEDQGEYSFVIDG---------------KKTTCKLKM---- 2305
Query: 547 APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG 606
KP LQGLSD KV +G V + V+VS E +W+ +G E+Q S+ H
Sbjct: 2306 ---KPRPIAILQGLSDQKVCEGDIVQLEVKVSLESV-EGVWMKDGQEVQPSDRVHIVIDK 2361
Query: 607 TQHSLCIQEVFPEDTGTYT----CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
H L I+++ ED G Y+ +++G V +V I+ + V
Sbjct: 2362 QSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV------------ITPLKDVN 2409
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
G ++ C ++ +V W + + + K + + LV+ + G
Sbjct: 2410 VIEGTKAVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGP 2468
Query: 723 YEILLKNRVGECSCQVSL 740
Y++++ RV E +C +S+
Sbjct: 2469 YKLIV-GRV-ETNCNLSV 2484
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 1/110 (0%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
EK P F K + + ++ G A + G P P++ WF + + S ++ +D D
Sbjct: 3451 EKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGD 3510
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
+ SLII +D+ +YTC A N G+ C+A L + + EG + E E
Sbjct: 3511 DH-SLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETE 3559
Score = 58.9 bits (141), Expect = 4e-08
Identities = 71/338 (21%), Positives = 128/338 (37%), Gaps = 62/338 (18%)
Query: 1062 WTLNGKTLKTTKFIILS-QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD 1120
W T+K TK + EGSL +++ A+N GQ++ + ++D
Sbjct: 7633 WQTVDTTVKDTKCTVTPLTEGSLY-------------VFRVAAENAIGQSDYT---EIED 7676
Query: 1121 APASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKV 1180
+ +++T + PP D T + PPK I ++ ++K
Sbjct: 7677 SVLAKDTFT---------TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKE 7727
Query: 1181 RAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
R G W+K K + +V + G+++ + G
Sbjct: 7728 RLGTR----------------WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAG--- 7768
Query: 1241 LLVENKLGSRQAQVNLTVVDKPDPPAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSY 1297
+G + ++ P P P +D + ++W +GGS + Y
Sbjct: 7769 ------VGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGY 7822
Query: 1298 SIEIWDSANKTWKELAT--CRSTSFNVQD-LLPDHEYKFRVRAINVYGTSEPSQESELTT 1354
+E+ + W + + + F V++ ++PD EY RVRA+N G SEPS+ SE
Sbjct: 7823 HVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVV 7882
Query: 1355 VGEKPEEPKDEVEVSDDDEKEPE-----VDYRTVTINT 1387
+ +P ++E D E E V +R V + T
Sbjct: 7883 AKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPT 7920
Score = 58.9 bits (141), Expect = 4e-08
Identities = 75/315 (23%), Positives = 112/315 (35%), Gaps = 53/315 (16%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G+ L+ V P TI W K ++ + + + ++ A+ D G Y
Sbjct: 17140 VNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQY 17199
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
A N AG V V D P P V G S+ K
Sbjct: 17200 ILRASNVAGSKSFPVNVKVLDRPG-------------PPEGPVQVTGVTSE----KCSLT 17242
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVEN 1219
+PP I + +++ E+ L V ++ +T
Sbjct: 17243 WSPPLQDGGSDISHYVVEKR----ETSRLAWTVVASEVVT-------------------- 17278
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDI 1274
N K+T L E+ + ++ NK G + + V+ K P PP ++I
Sbjct: 17279 --NSLKVTKLLEGNEYV--FRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLE-VTNI 17333
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN--VQDLLPDHEYK 1332
S+T+ W DGGS + Y +E D + W + R T V L DHEY+
Sbjct: 17334 AKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYE 17393
Query: 1333 FRVRAINVYGTSEPS 1347
FRV A N G EPS
Sbjct: 17394 FRVSAENAAGVGEPS 17408
Score = 58.5 bits (140), Expect = 6e-08
Identities = 63/295 (21%), Positives = 120/295 (40%), Gaps = 37/295 (12%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST---CEA 494
L V+E P F+ L+D +E + +LQC + P + W +G+ I+ +++ +
Sbjct: 5514 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADG 5572
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
L ++ AL D G YTC G S + + +++
Sbjct: 5573 KKRMLILKKALKSDIGQYTC----DCGTDKTSGKLDIEDREIK----------------- 5611
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
++ L ++VM+ ++S + W G + ++ D ++ G HSL +
Sbjct: 5612 -LVRPLHSVEVMETETARFETEISEDDI-HANWKLKGEALLQTPDCEIKEEGKIHSLVLH 5669
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ TG +A N V++ A L V+ G + + VT + G++ C
Sbjct: 5670 NCRLDQTGGVDFQAAN----VKSSAHLRVKPRVIG----LLRPLKDVTVTAGETATFDCE 5721
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
++ + P V W GK L + + V TL L+ V+ AG+ ++ K+
Sbjct: 5722 LSYEDIP-VEWYLKGKKL-EPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5774
Score = 58.5 bits (140), Expect = 6e-08
Identities = 72/338 (21%), Positives = 118/338 (34%), Gaps = 53/338 (15%)
Query: 1021 RSESQGTAPAFKQKLQDVHVAE-GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII-LS 1078
R E + K +DV V G+ +L+ + P ++W+ +GK L+ T + +
Sbjct: 18202 RDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIK 18261
Query: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138
++ ++ + D G Y N G V V D P P
Sbjct: 18262 STIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPG-------------PP 18308
Query: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1198
V G ++ P A + II+ E ++
Sbjct: 18309 EGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL------------------ 18350
Query: 1199 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+W + ++Q + K+T L E+ + ++ NK G + + V
Sbjct: 18351 --SWTQVSTEVQALNY----------KVTKLLPGNEYI--FRVMAVNKYGIGEPLESGPV 18396
Query: 1259 VD----KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-- 1312
KP P TP S I S+ ++W DGG+ ++ Y +E D W +
Sbjct: 18397 TACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNK 18456
Query: 1313 ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
T V L H Y+FRV A N G EPS+ S
Sbjct: 18457 KTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPS 18494
Score = 58.5 bits (140), Expect = 6e-08
Identities = 56/243 (23%), Positives = 88/243 (36%), Gaps = 34/243 (13%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
EAP +++ K G A+ ++ G P P + W+R G+ + ++ + R T +
Sbjct: 24034 EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGR-THT 24092
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L + +ED G YTC ATN G + + +L ++ + G P+ K G
Sbjct: 24093 LTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYG--------- 24143
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
G R GRP P +TW G LQ S +++
Sbjct: 24144 ----------------------AVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIE 24181
Query: 211 EKNGMQVLEIHGV-NQDDVGVYTCLVVNGSGKASMSAELSIQGL-DSANRSFVRETKATN 268
L + V + G Y + N G ++ IQ D V E N
Sbjct: 24182 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKN 24241
Query: 269 SDV 271
S V
Sbjct: 24242 SAV 24244
Score = 58.5 bits (140), Expect = 6e-08
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 1260 DKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRS 1317
+KP P G P + + S ++W + DGG+ +++Y +E + W + T R
Sbjct: 24326 EKPGAP-GKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24384
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
T F+V++L+ EY+FRV+ N+ G SE S+ SE P PK +V + KE
Sbjct: 24385 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISE-------PITPKSDVPIQAPHFKE 24435
Score = 58.5 bits (140), Expect = 6e-08
Identities = 49/175 (28%), Positives = 74/175 (42%), Gaps = 22/175 (12%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEG-SLCSVS 1087
P FK+ L + EG+ + + +VS PP T+ W +G+ L I + EG ++
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP-ASENTKAPEMKSRRPKSSLPPVL- 1145
I LPED G Y+ A N AG C + V+ + K+ E R + + L
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQIDKTLR 25417
Query: 1146 ------GTES------------DATVKKKPAPKTPP-KAAMPPQIIQFPEDQKVR 1181
GTES +A V KPA T K +I + E++K+R
Sbjct: 25418 MAEILSGTESVPLTQVAKEALREAAVLYKPAVSTKTVKGEFRLEIEEKKEERKLR 25472
Score = 57.8 bits (138), Expect = 9e-08
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD-EDGNCSL 1747
PYF ++VEG + F C++ G P P V W K + +++ Y+ + G C L
Sbjct: 1036 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1095
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+IS DD +YT N GE + +A L+ E
Sbjct: 1096 VISMTFADDAGEYTIVVRNKHGETSASASLLEE 1128
Score = 57.8 bits (138), Expect = 9e-08
Identities = 32/110 (29%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 1239 YTLLVENKLGSRQAQVNLTVVDKPDPPA--GTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ ++ EN+ G + V +PP+ G +D+ +S +L W +DGGS V
Sbjct: 17690 FRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLG 17749
Query: 1297 YSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
Y +E+ + W +A + + V L EY+FRV+A N G S+P
Sbjct: 17750 YVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDP 17799
Score = 57.8 bits (138), Expect = 9e-08
Identities = 35/128 (27%), Positives = 59/128 (46%), Gaps = 3/128 (2%)
Query: 1670 EDVSQAFLEAVAEEKPH---VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
ED +A L P ++P F + + + E EG + F+ ++ G P P + W KD
Sbjct: 25276 EDSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG 25335
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
Q + + +I ++ +L I D +D Y A N+ G +C A L VE + +
Sbjct: 25336 QPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKK 25395
Query: 1787 GEGEEEEE 1794
E + +EE
Sbjct: 25396 QEFKSKEE 25403
Score = 57.4 bits (137), Expect = 1e-07
Identities = 65/290 (22%), Positives = 112/290 (38%), Gaps = 42/290 (14%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAEL 499
A LK+ V E QD V + V + W+ NG ++ YA S + + L
Sbjct: 2660 AVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV-KGTIYSL 2718
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ D Y LG++ SA + V K +K +
Sbjct: 2719 RIKNCAIVDESVYGF----RLGRLGASARLHVETVKIIKKPK------------------ 2756
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
D+ ++ + V V VS + P V W H EI+ S+ H L +Q + P
Sbjct: 2757 --DVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPS 2813
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDP 679
D G YT G++ +A L V+ H I P + TAS C ++
Sbjct: 2814 DAGEYTA----VVGQLECKAKLFVETLHITKTMKNIEVPETKTAS------FECEVSHFN 2863
Query: 680 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
P++ WL++G + + + F+++ + L++ + +Y + N
Sbjct: 2864 VPSM-WLKNGVEI-EMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTFVCGN 2911
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG-NCSL 1747
P + ++ + V G ARF I G P P++ W+K++Q + S F+ + DG +L
Sbjct: 3193 PQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL--STGFKCKFLHDGQEYTL 3250
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
++ + +D A YTC+A N G AT +A L VE E
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/118 (34%), Positives = 56/118 (47%), Gaps = 8/118 (6%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---C 1315
V KP PP D +S+TL+W YDGGS + Y +EI + + W+ +
Sbjct: 17420 VFKPGPPTNAHIV-DTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGL 17478
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDE 1373
R T F + L EYK RV A+N G E + S TV KPE+ + E+ D E
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEAT--SVPGTV--KPEDKLEAPELDLDSE 17532
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 3/119 (2%)
Query: 1233 QEHCGCY-TLLVENKLG-SRQAQVNLTV-VDKPDPPAGTPCASDIRSSSLTLSWYGSSYD 1289
QE C Y +L N+ G A+ V V +P P G D+ ++ T+ W D
Sbjct: 18766 QEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESD 18825
Query: 1290 GGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQ 1348
GGS + Y +E+ ++ W ++ + L EY FRV A+N G S+P Q
Sbjct: 18826 GGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884
Score = 56.6 bits (135), Expect = 2e-07
Identities = 92/417 (22%), Positives = 146/417 (35%), Gaps = 55/417 (13%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
PA LQD +EG+ QC+VS + W K +K ++F ++Q + I
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTD-LKVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS------ENTKAPEMK--------- 1133
+A PED G Y VA N GQ + +++ +AP S E EMK
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSL-EAPESILHERIEQEIEMEMKEFSSSFLSA 3416
Query: 1134 -------SRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+ S + L S++ V P K P I+ + + G+
Sbjct: 3417 EEEGLHSAELQLSKINETLELLSESPV--YPTKFDSEKEGTGPIFIKEVSNADISMGDVA 3474
Query: 1187 ELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENK 1246
L V G W + S K + L IL + E G YT + N
Sbjct: 3475 TLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASND 3534
Query: 1247 LGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSY-----------DGGSAVQ 1295
G L + K + T S + S L + G A+
Sbjct: 3535 YGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIF 3594
Query: 1296 SYSIEIWDSANKTW----KELATC----------RSTSFNVQDLLPDHEYKFRVRAINVY 1341
Y++ + TW K+L T S +F V D + + +A N+
Sbjct: 3595 EYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENML 3654
Query: 1342 GTSEPSQE----SELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDF 1394
G S + E E T + + P + K E +D + P +++EQ+++ F
Sbjct: 3655 GESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATF 3711
Score = 56.6 bits (135), Expect = 2e-07
Identities = 83/362 (22%), Positives = 140/362 (38%), Gaps = 34/362 (9%)
Query: 852 EQMDFRANLQRQVKPKTVSEEERK-VHSPQQVDFRSVLAK-KGTSKTPVPEKVPPPKPAT 909
E+MD + Q+ V+P T E E K + S ++V + +V ++ K TPV + V +
Sbjct: 4142 EEMDSFSGSQK-VEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200
Query: 910 P-DFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL--KPVGNAKPAE-- 964
S+ ++K + + S + E K E+ L + GP+ P+ + E
Sbjct: 4201 EKQDESLKPSEEKEESSSESGTEEVATVKIQEAEGGL--IKEDGPMIHTPLVDTVSEEGD 4258
Query: 965 ---TLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG------- 1014
+ NAK DE K + V + VN + H G
Sbjct: 4259 IVHLTTSITNAKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTE-DHQGEYVCEAL 4317
Query: 1015 -----TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL 1069
T + K + + AP K+K++ + VA G C++ S P W G+ +
Sbjct: 4318 NDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREI 4377
Query: 1070 KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKA 1129
+ + + S+ I + D G Y C A N+ G C+ +TV P E
Sbjct: 4378 YESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGEKKVR 4436
Query: 1130 PEMKSRRPKSSLPPVLGTESDATVKKKP---APKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+ R+P+ VL + ++K+P PK PK + PE + E V
Sbjct: 4437 KLLPERKPEPKEEVVL----KSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEV 4492
Query: 1187 EL 1188
E+
Sbjct: 4493 EV 4494
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/317 (21%), Positives = 120/317 (37%), Gaps = 58/317 (18%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
V G + + VS PP T+ W +N +TL I + S S+ I+ +G+Y
Sbjct: 10039 VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISS--SMVIKNCQRSHQGVY 10096
Query: 1100 KCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAP 1159
+AKN+AG+ + + V V D P T P + S
Sbjct: 10097 SLLAKNEAGERKKTIIVDVLDVPGPVGT--PFLAHNLTNESC------------------ 10136
Query: 1160 KTPPKAAMPPQIIQF-PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVE 1218
++ F PED G PIT ++ +++ V
Sbjct: 10137 ----------KLTWFSPEDD---------------GGSPIT-NYVIEKRESDRRAWTPVT 10170
Query: 1219 NSENGSKLTILAARQEHCGCYTLLVENKLG------SRQAQVNLTVVDKPDPPAGTPCAS 1272
+ T+ Q + + EN +G + +A V + P+ P
Sbjct: 10171 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLE-VK 10229
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA--TCRSTSFNVQDLLPDHE 1330
++ +++TL+W YDGGS + +Y +E + + ++ S + V+ L
Sbjct: 10230 EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDT 10289
Query: 1331 YKFRVRAINVYGTSEPS 1347
Y++RV A+N+ G +PS
Sbjct: 10290 YEYRVSAVNIVGQGKPS 10306
Score = 56.6 bits (135), Expect = 2e-07
Identities = 66/316 (20%), Positives = 112/316 (35%), Gaps = 53/316 (16%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + ++ V P T+ W + LK T+ + + ++I + + D G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A+N G+ + V D P PP + D
Sbjct: 14643 ARNIVGEVGDVITIQVHDIPG------------------PPTGPIKFDE----------- 14673
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
+ + F D G V Q + TW++ + + +
Sbjct: 14674 ----VSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV-------IRTTYK 14722
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK-----PDPPAGTPCASDIRSS 1277
++LT Q + + +N+ G + +V P PP GTP + +
Sbjct: 14723 ATRLTTGLEYQ-----FRVKAQNRYGVGPGITSACIVANYPFKVPGPP-GTPQVTAVTKD 14776
Query: 1278 SLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYKFRV 1335
S+T+SW+ DGGS + Y +E + W+ + A F L Y+FRV
Sbjct: 14777 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV 14836
Query: 1336 RAINVYGTSEPSQESE 1351
A N+ G S+PS+ SE
Sbjct: 14837 IAENMAGKSKPSKPSE 14852
Score = 56.6 bits (135), Expect = 2e-07
Identities = 74/390 (18%), Positives = 140/390 (35%), Gaps = 53/390 (13%)
Query: 988 ENLKSASKEELKKDVKNDVNCKRGH-AGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKL 1046
E L ++ E + KND A ++ K + + TA Q + G
Sbjct: 22109 ERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPF 22168
Query: 1047 LLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKND 1106
+ +S P + W L LK T + ++ +++++ ++ D G Y +N
Sbjct: 22169 TIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENT 22228
Query: 1107 AGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAA 1166
AG S V V P P + V +++ V PK
Sbjct: 22229 AGVKTFSVTVVVIGRPG-------------PVTGPIEVSSVSAESCVLSWGEPKDGGGTE 22275
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
+ I++ E T W ++ ++ K+
Sbjct: 22276 ITNYIVEKRESG--------------------TTAWQLVNSSVKRTQ----------IKV 22305
Query: 1227 TILAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCASD---IRSSSLTLS 1282
T L E+ + + EN+ G S+ + + + P P P + + ++++++
Sbjct: 22306 THLTKYMEY--SFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIR 22363
Query: 1283 WYGSSYDGGSAVQSYSIEIWDSANKTW--KELATCRSTSFNVQDLLPDHEYKFRVRAINV 1340
W +DGGS + Y +E + W + C ++ V L+ EY+FR A+N
Sbjct: 22364 WEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNA 22423
Query: 1341 YGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
G S+ S+ S + + P + EV+D
Sbjct: 22424 AGVSKASEASR-PIMAQNPVDAPGRPEVTD 22452
Score = 56.2 bits (134), Expect = 3e-07
Identities = 41/142 (28%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT---CRST 1318
P P P +D S +L+W YDGG + Y +E ++ W + T R T
Sbjct: 14175 PPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRIT 14234
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEV 1378
F V DL +Y FR+ AIN G EP+ ++ V E E++ D E + E+
Sbjct: 14235 QFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIV---------EREMAPDFELDAEL 14285
Query: 1379 DYRTVTINTEQKVSDFYDIEER 1400
RT+ + + F I+ R
Sbjct: 14286 -RRTLVVRAGLSIRIFVPIKGR 14306
Score = 56.2 bits (134), Expect = 3e-07
Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVA--ELH 500
P F +L + EGQ + V G P P + W +GQP+ + G+ LH
Sbjct: 25298 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALH 25357
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY 542
I+D LPED G Y A N G SC A + V E+ +K E+
Sbjct: 25358 IRDTLPEDTGYYRVTATNTAGSTSCQAHLQV-ERLRYKKQEF 25398
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/130 (28%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
Query: 1657 PTSPLNAEKLESEEDVSQ--AFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEG 1714
P +++E E ++ A ++K KP + V+EG ARF C++ G
Sbjct: 1761 PEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTG 1820
Query: 1715 YPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
YP P+V W+ + Q IR+S+ F++ Y DG L I D D + A N G
Sbjct: 1821 YPQPKVNWYLNGQLIRKSKRFRVRY--DGIHYLDIVDCKSYDTGEVKVTAENPEGVIEHK 1878
Query: 1775 AELIVETMEE 1784
+L ++ E+
Sbjct: 1879 VKLEIQQRED 1888
Score = 55.8 bits (133), Expect = 4e-07
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 8/133 (6%)
Query: 1237 GC---YTLLVENKLGSRQAQVNLTVV---DKPDPPAGTPCASDIRSSSLTLSWYGSSYDG 1290
GC + ++ EN+ G + V + P PP DI S+++L+W +DG
Sbjct: 14437 GCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIM-DITKSTVSLAWPKPKHDG 14495
Query: 1291 GSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQES 1350
GS + Y IE + W + T + V++L EY F+V A+N G S P +ES
Sbjct: 14496 GSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAP-RES 14554
Query: 1351 ELTTVGEKPEEPK 1363
V E+ P+
Sbjct: 14555 RPVIVKEQTMLPE 14567
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/241 (21%), Positives = 83/241 (34%), Gaps = 46/241 (19%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
AP F Q LQ V V EG + +S P + W +G+ + T+ + +S
Sbjct: 5 APTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAK 64
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
++I + G Y A N +GQA + ++ V A
Sbjct: 65 LTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA---------------------- 102
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKF 1205
PP +Q + VR G V L +VTG + +
Sbjct: 103 ----------------------PPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRD 140
Query: 1206 RKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
+IQ S ++ + L I A E G Y++ N +G + L V + + P
Sbjct: 141 GAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGEEEVP 200
Query: 1266 A 1266
A
Sbjct: 201 A 201
Score = 55.5 bits (132), Expect = 5e-07
Identities = 33/97 (34%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQS-IRESRHFQIDYDEDG 1743
P P+F + +R+L V S A CK+ G+P P V W++ + I + ++I + G
Sbjct: 24427 PIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGG 24486
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
LII+ V DD Y +A N G + TA L VE
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 55.5 bits (132), Expect = 5e-07
Identities = 34/96 (35%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F R + EG F C+I G P PE+ WFK++ I S + I + SL
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN-VYSLE 26695
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I + D KYT KA N G+ + TA L+V + E
Sbjct: 26696 IRNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVE 26731
Score = 55.1 bits (131), Expect = 6e-07
Identities = 35/113 (30%), Positives = 53/113 (46%), Gaps = 4/113 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CRSTS 1319
P PP P +D SS L W DGGS V Y +E + + W++ R T
Sbjct: 9925 PGPPF--PKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTK 9982
Query: 1320 FNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
V L YKFRVRA+N+ G EP + +++ + ++ P +++ S D
Sbjct: 9983 LVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRD 10035
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1261 KPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL---ATCRS 1317
KP P P D + L W DGGS + Y +E W + R
Sbjct: 11305 KPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIRQ 11364
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDD 1372
+F V L+ +EY+FR++A N+ G EP + +E + P+ E++V+ D
Sbjct: 11365 CAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419
Score = 55.1 bits (131), Expect = 6e-07
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 33/243 (13%)
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG--KVTG-----TQPIT 1199
TES + K K P PP++ + +++ E G +TG + +
Sbjct: 11885 TESKPVIAKTKYDK--PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHS 11942
Query: 1200 CTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVV 1259
W+ K MKV+N +H + + EN++G + + V
Sbjct: 11943 TRWVPVNKSAIPERRMKVQN-----------LLPDHEYQFRVKAENEIGIGEPSLPSRPV 11991
Query: 1260 DKPDP--PAGTPC---ASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWD-----SANKTW 1309
DP P G P D S+TL W YDGG+ + Y +E+ S ++ W
Sbjct: 11992 VAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGW 12051
Query: 1310 KEL---ATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
K A F V L + EY+FRV A N G P++ E E E P+ ++
Sbjct: 12052 KRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111
Query: 1367 EVS 1369
+ S
Sbjct: 12112 DAS 12114
Score = 55.1 bits (131), Expect = 6e-07
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 1273 DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST--SFNVQDLLPDHE 1330
D+ S++TL+W YDGGS + Y +E + + W ++ T + T V L +
Sbjct: 23148 DVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEGEQ 23207
Query: 1331 YKFRVRAINVYGTSEPSQESELTTV 1355
Y FR+RA N G SEP + TV
Sbjct: 23208 YLFRIRAQNEKGVSEPRETVTAVTV 23232
Score = 55.1 bits (131), Expect = 6e-07
Identities = 65/266 (24%), Positives = 104/266 (39%), Gaps = 36/266 (13%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-----QYARSTCEAGVAE 498
AP F L++ V + L C V G P P + W G+ I +Y + G +
Sbjct: 24430 APHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQ 24489
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I +D Y A N G VS +A + V P+K P L+
Sbjct: 24490 LIIASVTDDDATVYQVRATNQGGSVSGTASLEVE--------------VPAKIHLPKTLE 24535
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
G+ + + G V++ + SG P P + W G ++ ++ H++ T+ + VFP
Sbjct: 24536 GMGAVHALRGEVVSIKIPFSGKPDPVITW-QKGQDLIDNNG-HYQVIVTRSFTSL--VFP 24591
Query: 619 -----EDTGTYTCEAWNSAG---EVRTQAVLTVQEPHDGTQPWFISKPR-----SVTASL 665
+D G Y A N G + V V +P G + +S+ + AS
Sbjct: 24592 NGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASD 24651
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA 691
G S + + + WLR G+A
Sbjct: 24652 GGSKITNYIVEKCATTAERWLRVGQA 24677
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEI--WD---SANKTWKEL--AT 1314
PDPP I +++ LSW DGGS V Y +E WD + + W++
Sbjct: 9515 PDPPIKLKIGL-ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRD 9573
Query: 1315 CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVG----EKPEEP 1362
F V+DL+ EY+FRV+A+N G S+PS TVG ++P+ P
Sbjct: 9574 VEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS-----ATVGPCDCQRPDMP 9620
Score = 54.7 bits (130), Expect = 8e-07
Identities = 41/132 (31%), Positives = 59/132 (44%), Gaps = 12/132 (9%)
Query: 1239 YTLLVENKLG--SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQS 1296
+ + EN G S T+ P P GTP D+ ++TL W DGGS +
Sbjct: 21332 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21391
Query: 1297 YSIEIWDSANKTW-----KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQES 1350
YSIE N+ W +++ C+ + V L P Y+FR+ A N GT S PSQ S
Sbjct: 21392 YSIE-KRQGNERWVRCNFTDVSECQ---YTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447
Query: 1351 ELTTVGEKPEEP 1362
+ ++ P
Sbjct: 21448 GIIMTRDENVPP 21459
Score = 54.3 bits (129), Expect = 1e-06
Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 5/117 (4%)
Query: 1677 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+EAV + VKP F + ++++ + EGS + G P+P++VW K+ I ++ +
Sbjct: 1501 VEAVEHQ---VKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPK 1557
Query: 1737 IDYD-EDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
I + G +L I D A YT A+N G T ++ VE +E E E E +
Sbjct: 1558 IRIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVE-VEFAEPEPERK 1613
Score = 54.3 bits (129), Expect = 1e-06
Identities = 82/353 (23%), Positives = 125/353 (35%), Gaps = 50/353 (14%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN-GKTLKTTKFIILSQEGSLCSVSIE 1089
F+ KL + G+ L + S P + W + L+ + I + +L I
Sbjct: 10327 FRDKLT---IRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKI- 10382
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTES 1149
KA D G Y V +N G + CQV V D P PPV
Sbjct: 10383 KAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPG------------------PPVGPVSF 10424
Query: 1150 DATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI 1209
D K P I +K G+ V + + + TC K K +
Sbjct: 10425 DEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWM-PVTSASAKTTC---KVSKLL 10480
Query: 1210 QESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTP 1269
+ +++ ++EN Y + S +A+ V D PD P T
Sbjct: 10481 EGKDYIFRIHAEN---------------LYGISDPLVSDSMKAKDRFRVPDAPDQPIVTE 10525
Query: 1270 CASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS---TSFNVQDLL 1326
D S ++W +DGG + +Y +E ++ +K W + T F V DLL
Sbjct: 10526 VTKD----SALVTW-NKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLL 10580
Query: 1327 PDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVD 1379
+Y+FRV A N G +PS S+ + +P V D VD
Sbjct: 10581 EGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVD 10633
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 17/114 (14%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QL PV++K L PP F V G+ + GRP
Sbjct: 15636 RQLSVPVIAKDL-----------------VIPPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15678
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
P VTW K NVPL+ + RV+ +L I ++DVG Y + N +G+A
Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732
Score = 54.3 bits (129), Expect = 1e-06
Identities = 26/77 (33%), Positives = 44/77 (57%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
V+ GQ + I+GRP+P +TW K +PL+ + R++V++ + L I ++DD G Y
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 16803
Query: 232 TCLVVNGSGKASMSAEL 248
V N G+ + S E+
Sbjct: 16804 GITVANVVGQKTASIEI 16820
Score = 54.3 bits (129), Expect = 1e-06
Identities = 32/94 (34%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR---ESRHFQIDYDEDGNC 1745
P F+ + + G RF I +P+P V W+K Q I+ + + + D+ G
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDK-GLY 25251
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I+ V DDDA+YT A N GE +C A+L V
Sbjct: 25252 QLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 53.9 bits (128), Expect = 1e-06
Identities = 42/120 (35%), Positives = 57/120 (47%), Gaps = 6/120 (5%)
Query: 1667 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
+S + + A L V P +K + I LEV G A+F C+I+ P+ WFK
Sbjct: 4319 DSGKTATSAKLTVVKRAAPVIK----RKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAG 4374
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
+ I ES I + + SL I D +YTCKA N G +CTA L V T+ GE
Sbjct: 4375 REIYESDKCSIRSSKYIS-SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV-TVPGGE 4432
Score = 53.9 bits (128), Expect = 1e-06
Identities = 31/111 (27%), Positives = 51/111 (45%), Gaps = 1/111 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E A E KP ++D V S A+F K G P P +W KD ++I + +++
Sbjct: 26344 EPKAPEPISSKPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKL 26403
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGE 1788
D+ G L I D YTC NS G + + +L ++ +++ E +
Sbjct: 26404 SEDK-GGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIKAIKDTEAQ 26453
Score = 53.5 bits (127), Expect = 2e-06
Identities = 66/288 (22%), Positives = 114/288 (39%), Gaps = 41/288 (14%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDA 504
+ +K+ V E + +C V VP + WL NG I+ + + + +L I +
Sbjct: 2839 TKTMKNIEVPETKTASFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNT 2897
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG-LSDL 563
ED YT + N QVS + VT PI + L D+
Sbjct: 2898 STEDSAEYTFVCGN--DQVSATLTVT-----------------------PIMITSMLKDI 2932
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
+ +T V V+ WL NG EI+ ++ + HSL I+ V D
Sbjct: 2933 NAEEKDTITFEVTVNYEGI-SYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAAD 2991
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
YT AG+ + A L V+ H F + + + + C ++ +P TV
Sbjct: 2992 YTF----VAGKATSTATLYVEARHIE----FRKHIKDIKVLEKKRAMFECEVS-EPDITV 3042
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRV 731
W++D + L + T ++ + + V L++ + AG+Y ++ V
Sbjct: 3043 QWMKDDQEL-QITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNV 3089
Score = 53.1 bits (126), Expect = 2e-06
Identities = 95/436 (21%), Positives = 157/436 (36%), Gaps = 67/436 (15%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
++ G R I GRP P+V W K + ++ +A + V+ VL+ VN+ D G Y
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD--NVNRYDSGKY 16514
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAA 291
T + N SG + SA ++++ LD+ + N V + + +S + L+
Sbjct: 16515 TLTLENSSG--TKSAFVTVRVLDT-------PSPPVNLKVTEITKDSVSITWEPPLLDGG 16565
Query: 292 AKSKNCSSPQRGGS-PPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
+K KN +R + +AA K++ ++ + V + I L A
Sbjct: 16566 SKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEG--CSYYFRVTAENEYGIGLPAQ 16623
Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
P A V P G+ + +P D SK + M+ +
Sbjct: 16624 TADPIKVAE---VPQPPGKITVDDVTRNSVSLSWTKP---EHDGGSKIIQYIVEMQAKHS 16677
Query: 411 SAFPKFESKPQSQEVKENQT----VKFRC-----------EGLAVMEVA------PSFSS 449
+ + Q V N T FR LAV VA P
Sbjct: 16678 EKWSECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKP 16737
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALP 506
+V GQD ++ + G P P ITW +G P++ T + L I++
Sbjct: 16738 AFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHK 16797
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+D G Y N +GQ + S + +K P P P+ +S
Sbjct: 16798 DDGGQYGITVANVVGQKTASIEIVTLDK-------------PDPPKGPVKFDDVS----- 16839
Query: 567 DGSQVTMTVQVSGNPP 582
++ +S NPP
Sbjct: 16840 -----AESITLSWNPP 16850
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/82 (29%), Positives = 41/82 (50%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+++K G+ R + GRP P+VTW K V ++ + +++ G L + +D G
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 21530
Query: 230 VYTCLVVNGSGKASMSAELSIQ 251
VYT N SG A ++ +Q
Sbjct: 21531 VYTVEAKNASGSAKAEIKVKVQ 21552
Score = 53.1 bits (126), Expect = 2e-06
Identities = 24/92 (26%), Positives = 53/92 (57%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P K ++D+ G AA+ C+I G P P++ W++ + + +SR +++ D + +
Sbjct: 24036 PGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTV 24095
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+++ +D+ YTC A N +GE +++L+++
Sbjct: 24096 MTEE-QEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 12/199 (6%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
PT + + V G V + + ++G PPP W G++++ESE E
Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEV-RTQAVLTVQEPHDGTQPWFISK--PRSVTASL-- 665
L I+E DTG YT E N G T V+ + +P T P I + S+T S
Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23358
Query: 666 ----GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAG 721
G + L + WL +++ + T F L + + + + G
Sbjct: 23359 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIG 23418
Query: 722 QYEILLKNRVGECSCQVSL 740
Y L++ V EC + +
Sbjct: 23419 SY---LQSEVIECRSSIRI 23434
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR-GTFS 90
AP FI P + EG + F +V G P+P V W ++G P+T+G R+ + + G
Sbjct: 1035 APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK 1094
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSF 127
LVI +D G+YT N G + L E +
Sbjct: 1095 LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADY 1131
Score = 52.4 bits (124), Expect = 4e-06
Identities = 33/119 (27%), Positives = 53/119 (44%), Gaps = 2/119 (1%)
Query: 1661 LNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV 1720
++A+ + D Q + +A++ + P F V+ G + D G P P V
Sbjct: 15624 VSAQNEKGISDPRQLSVPVIAKDLV-IPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAV 15682
Query: 1721 VWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
W KD+ ++++ + E+ N L I D C +D Y K NS GEA T +IV
Sbjct: 15683 TWHKDNVPLKQTTRVNAESTEN-NSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIV 15740
Score = 52.4 bits (124), Expect = 4e-06
Identities = 94/441 (21%), Positives = 159/441 (36%), Gaps = 63/441 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V ++ G R ++GRP P +TW K + L A + +E + +++ VN+ D G
Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD--KVNRYDAG 23016
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVRKE---------VTNVI 279
YT N SGK S + + + S V+E + + E V N I
Sbjct: 23017 KYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYI 23076
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSP------------PWAANSQPQPPRESKLESCKD 327
++ + + CS S P +P S +
Sbjct: 23077 VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSE 23136
Query: 328 SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQP 387
P + V+ T S++TL +P G L+ E + R T +P
Sbjct: 23137 VPLVPAKLEVVDVTKSTVTL----AWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23192
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSF 447
+ V S EG++ + +++ E +E T + L V+
Sbjct: 23193 TVLEHTVTSL-------NEGEQYLFRIRAQNEKGVSEPRETVTA-VTVQDLRVLPTIDLS 23244
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCE--AGVAELHIQDA 504
+ K V G+ L + G P P +W G ++ + R T E VA+L I++
Sbjct: 23245 TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRET 23304
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
D G YT +N G S + V + +K P PT PI +
Sbjct: 23305 TIRDTGEYTLELKNVTGTTSETIKVIILDK-------------PGPPTGPI------KID 23345
Query: 565 VMDGSQVTMTVQVSGNPPPEV 585
+D + +T++ + PPE+
Sbjct: 23346 EIDATSITISWE-----PPEL 23361
Score = 52.4 bits (124), Expect = 4e-06
Identities = 62/233 (26%), Positives = 97/233 (41%), Gaps = 22/233 (9%)
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG---KVTGTQPITCTWMKFRKQIQE 1211
K P TP PP+ P + SV L K G +T +++ ++ +
Sbjct: 23818 KSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTD 23877
Query: 1212 S--EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG-SRQAQVNLTVV-----DKPD 1263
H K + + +T L E+ + ++ +N +G S + + VV DKP
Sbjct: 23878 KWVRHNKTQITTTMYTVTGLVPDAEYQ--FRIIAQNDVGLSETSPASEPVVCKDPFDKPS 23935
Query: 1264 PPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCRSTSFN 1321
P S I S+TL W DGG + Y +E S + WK+ + F
Sbjct: 23936 QPGELEILS-ISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFT 23994
Query: 1322 VQDLLPDHEYKFRVRAINVYGTSEP-----SQESELTTVGEKPEEPKDEVEVS 1369
+ LL EY+FRV A N G S P S +++LT+ GE P K+ +V+
Sbjct: 23995 IGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTS-GEAPGIRKEMKDVT 24046
Score = 52.4 bits (124), Expect = 4e-06
Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 1/95 (1%)
Query: 171 VVKEGQMGRFSCKITGRPQP-QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V +EG ++ CKI Q QVTW G L+ S + ++ ++G+ +L + + + D G
Sbjct: 25081 VGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG 25140
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRET 264
Y C VVN G+ S AEL ++G+ + R T
Sbjct: 25141 TYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRT 25175
Score = 52.0 bits (123), Expect = 5e-06
Identities = 72/338 (21%), Positives = 111/338 (32%), Gaps = 54/338 (15%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
++ H+ G L L + P + W + T I ++ GS + I A ED
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS--KLEIRNAAHED 10786
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G+Y +N AG S +V V D P P+ + +S K
Sbjct: 10787 GGIYSLTVENPAGSKTVSVKVLVLDKPGP------------PRDLEVSEIRKDSCYLTWK 10834
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+P G SV V + W ++ H
Sbjct: 10835 EPLDD----------------------GGSVITNYVVERRDVASAQWSPLSATSKKKSHF 10872
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP--PAGTPCAS- 1272
+E L +AA EN+ G + DP P G P
Sbjct: 10873 AKHLNEGNQYLFRVAA------------ENQYGRGPFVETPKPIKALDPLHPPGPPKDLH 10920
Query: 1273 --DIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHE 1330
D+ + ++L W DGGS + Y +E + + W + T + V L
Sbjct: 10921 HVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKT 10980
Query: 1331 YKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEV 1368
Y+FRV+A N+ G P + EK P E++V
Sbjct: 10981 YRFRVKAENIVGLGLPDTTIPI-ECQEKLVPPSVELDV 11017
Score = 52.0 bits (123), Expect = 5e-06
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 1/104 (0%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L IK G + + + V+G P P+VTW ++G I + + G+ SL + + R
Sbjct: 21471 LIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHR 21529
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G YT EA N SG+ + +++ V+ + K +G + G++ +
Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573
Score = 51.6 bits (122), Expect = 7e-06
Identities = 90/418 (21%), Positives = 158/418 (37%), Gaps = 69/418 (16%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV+ G R I GRP P+VTW K N+ L+ A + +E +L I N+ D G
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE--SFTLLIIPECNRYDTG 14346
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF-VRETKATNSDVR-----------KEVTN 277
+ + N +GK S ++++ LD+ +R T T V +TN
Sbjct: 14347 KFVMTIENPAGK--KSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITN 14404
Query: 278 VISKE---SKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQ--PQPPRESKLESC 325
I ++ ++ A K C+ G S A N +P ++
Sbjct: 14405 YIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA 14464
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTR 385
++P ++ T S+++L P+P+ G ++ E +R + T
Sbjct: 14465 SEAPSPPDSLNIMDITKSTVSL----AWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTV 14520
Query: 386 QPGLGSQDVVSKAANR-----RIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAV 440
+ G + VV ++ + P+ ES+P + + QT+ L
Sbjct: 14521 K---GLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRP---VIVKEQTM------LPE 14567
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVA 497
+++ + ++ A G + ++ V G P P +TW Q + Q A
Sbjct: 14568 LDLRGIYQKLVIAKA---GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATST 14624
Query: 498 ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
L+I + + D G Y A N +G+V + VH+ P PT PI
Sbjct: 14625 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHD-------------IPGPPTGPI 14669
Score = 51.6 bits (122), Expect = 7e-06
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 18/153 (11%)
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG---SRQAQVNLTV 1258
W K K + + H KV G + + EN G +
Sbjct: 20219 WQKANKLVIRTTHFKVTTISAGLIYE-----------FRVYAENAAGVGKPSHPSEPVLA 20267
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+D +PP +DI +S++LSW ++DGGS + Y +E D + W +
Sbjct: 20268 IDACEPPRNVRI-TDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVT 20326
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGT-SEPSQ 1348
T F + L + +Y+FRV A N G+ S PS+
Sbjct: 20327 ETQFIISGLTQNSQYEFRVFARNAVGSISNPSE 20359
Score = 51.2 bits (121), Expect = 9e-06
Identities = 55/198 (27%), Positives = 76/198 (38%), Gaps = 39/198 (19%)
Query: 452 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPED 508
KD +E + SV VP + W +P R E V +L +Q+ P D
Sbjct: 2756 KDVTALENATVAFEVSVSHDTVP-VKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSD 2814
Query: 509 HGTYTCLAENALGQVSCSAWV---TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 565
G YT + +GQ+ C A + T+H K+ + E P TA
Sbjct: 2815 AGEYTAV----VGQLECKAKLFVETLHITKTMKNIE-----VPETKTA------------ 2853
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 625
+ +VS P + WL NG EI+ SE F +G H L I ED+ YT
Sbjct: 2854 ------SFECEVSHFNVPSM-WLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYT 2906
Query: 626 CEAWNSAGEVRTQAVLTV 643
N + A LTV
Sbjct: 2907 FVCGND----QVSATLTV 2920
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/113 (26%), Positives = 52/113 (46%), Gaps = 5/113 (4%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT--CR 1316
+ P PP P +D S+++ L W +++GG + Y ++ W +
Sbjct: 8503 ISPPGPPI--PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIK 8560
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ V+++ +YK RV A+N G P E++ TV E E P E++VS
Sbjct: 8561 VRQYTVKEIREGADYKLRVSAVNAAGEGPPG-ETQPVTVAEPQEPPAVELDVS 8612
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/323 (21%), Positives = 113/323 (34%), Gaps = 62/323 (19%)
Query: 1056 PPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSC- 1114
PP T+ W + K L + + S ++I + D G Y +N G+ + S
Sbjct: 20802 PPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTV 20861
Query: 1115 QVTVDDAPASENTKAPEMKSRRPKSSL--PPVLGTES---DATVKKKPAPKTPPKAAMPP 1169
V V D PA+ + SR + L PP++ S + ++K+ A K
Sbjct: 20862 SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKR-------- 20913
Query: 1170 QIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTIL 1229
TW + + ++ SE
Sbjct: 20914 -------------------------------TWSVVSHKCSSTSFKLIDLSEKTPFF--- 20939
Query: 1230 AARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS--DIRSSSLTLSWYGSS 1287
+ +L EN++G + V + PA S D +S+ LSW
Sbjct: 20940 ---------FRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPD 20990
Query: 1288 YDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPS 1347
+DGGS + Y +E +TW ++ V L +FRV A N G S+P
Sbjct: 20991 FDGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV 21050
Query: 1348 QESELTTVGEKPEEPKDEVEVSD 1370
+ TV E P EV++SD
Sbjct: 21051 TIGPI-TVKELIITP--EVDLSD 21070
Score = 50.8 bits (120), Expect = 1e-05
Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 9/157 (5%)
Query: 1220 SENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ--VNLTVVDKPDPPAGTPCA---SDI 1274
SE K+T L E+ + ++ EN G A L +P P G P +D
Sbjct: 21711 SETRFKVTGLTEGNEYE--FHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDT 21768
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL--ATCRSTSFNVQDLLPDHEYK 1332
++++L W +DGG + Y IE+ + W ++ C T + V DL EYK
Sbjct: 21769 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 21828
Query: 1333 FRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
FRV AIN G + + + ++ P+ +++ +
Sbjct: 21829 FRVSAINGAGKGDSCEVTGTIKAVDRLTAPELDIDAN 21865
Score = 50.1 bits (118), Expect = 2e-05
Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
G P + + VT LG++ +SC I G P P + W R GK L + + +++ +
Sbjct: 24033 GEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQ-SRKYKMSSDGRTH 24091
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
TL + + G Y + N VGE L+LQ
Sbjct: 24092 TLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQ 24126
Score = 49.7 bits (117), Expect = 3e-05
Identities = 36/155 (23%), Positives = 61/155 (39%), Gaps = 12/155 (7%)
Query: 145 SAPAVETRPSIWGECPPKF--ATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
S P E + E P F L + VK G +TG+P+P++TW K ++ L+
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILK 7235
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG---------- 252
R+++ + I + D G Y VN G+A+ E+++
Sbjct: 7236 QDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDI 7295
Query: 253 LDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
D N S + D ++TN + + DS
Sbjct: 7296 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS 7330
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/118 (29%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC------ 1315
P PP G P S+ +SW +GGS + Y +E + + W ++
Sbjct: 9102 PGPP-GKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKVG 9160
Query: 1316 -RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEK--PEEPKDEVEVSD 1370
+ FNV LL +Y+FR AIN G PS+ S+ G+ P P EV D
Sbjct: 9161 LKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKD 9218
Score = 49.7 bits (117), Expect = 3e-05
Identities = 76/335 (22%), Positives = 109/335 (32%), Gaps = 60/335 (17%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G + L V PP I W+ L+ + + + E D G Y
Sbjct: 13211 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 13270
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
+N G+ E + V V D P PPV T + + P
Sbjct: 13271 LENSCGKKEYTIVVKVLDTPG------------------PPVNVTVKEISKDSAYVTWEP 13312
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P II + ++ + K T C+ FR V N E
Sbjct: 13313 PIIDGGSPIINYVVQKR-------DAERKSWSTVTTECSKTSFR----------VANLEE 13355
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSL 1279
G + + EN+ G V P G +RS SS
Sbjct: 13356 GKSYF-----------FRVFAENEYGIGDPGETRDAVKASQTP-GPVVDLKVRSVSKSSC 13403
Query: 1280 TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEYKFRVRAIN 1339
++ W DGGS + Y ++ NK W+ + S ++ +DL EY FRV A N
Sbjct: 13404 SIGWKKPHSDGGSRIIGYVVDFLTEENK-WQRVMKSLSLQYSAKDLTEGKEYTFRVSAEN 13462
Query: 1340 VYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEK 1374
G P SE+T V +D+V D D K
Sbjct: 13463 ENGEGTP---SEITVVA------RDDVVAPDLDLK 13488
Score = 49.7 bits (117), Expect = 3e-05
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
S + +GQ + I I+G P PT+ W +DG L K T V + D+ TL +K+
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPL-KQTTRINVTDSLDLTTLSIKETHKDD 16799
Query: 720 AGQYEILLKNRVGECSCQVSLM 741
GQY I + N VG+ + + ++
Sbjct: 16800 GGQYGITVANVVGQKTASIEIV 16821
Score = 49.3 bits (116), Expect = 3e-05
Identities = 24/81 (29%), Positives = 40/81 (49%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ VK G + G+P P V+W K L+P+ + ++ + + LE+ VN+ D G
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSG 12867
Query: 230 VYTCLVVNGSGKASMSAELSI 250
YT N SG S + +L +
Sbjct: 12868 DYTITAENSSGSKSATIKLKV 12888
Score = 48.9 bits (115), Expect = 4e-05
Identities = 67/319 (21%), Positives = 114/319 (35%), Gaps = 50/319 (15%)
Query: 1062 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
W+ GK ++ + ++ + ++I+ A +D G Y A N G +VTV D
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975
Query: 1122 PASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVR 1181
P PP S+ + +K TPP I + +++
Sbjct: 13976 PG------------------PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKR-- 14015
Query: 1182 AGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTL 1241
E+ L W + IQ H+ + + G++ + H G
Sbjct: 14016 --ETSRLL------------WTVVSEDIQSCRHVATKLIQ-GNEYIFRVSAVNHYG---- 14056
Query: 1242 LVENKLGSRQAQVNLTVVDK--PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSI 1299
G + +VD+ P P P S++ ++ T+SW DGGS + Y +
Sbjct: 14057 -----KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHV 14111
Query: 1300 EIWDSANKTWKELATCRSTSF--NVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGE 1357
E + + W + V L Y+FRV A N G PS+ S+ + +
Sbjct: 14112 ERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 14171
Query: 1358 K--PEEPKDEVEVSDDDEK 1374
P P V+D +K
Sbjct: 14172 AAYPPGPPSNPHVTDTTKK 14190
Score = 48.5 bits (114), Expect = 6e-05
Identities = 92/445 (20%), Positives = 156/445 (35%), Gaps = 76/445 (17%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVY 231
+K G R S I G P P+VTW K + AR+ V+ LEI +D G+Y
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGSK--LEIRNAAHEDGGIY 10790
Query: 232 TCLVVNGSGKASMSAELSIQGLDSANR----SFVRET------KATNSDVRKEVTNVISK 281
+ V N +G ++S ++ + R S +R+ K D +TN + +
Sbjct: 10791 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 10850
Query: 282 ESKLDS-----LEAAAKSKN--CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQ 334
+ S L A +K K+ G + ++ Q R +E+ K P
Sbjct: 10851 RRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPL 10910
Query: 335 TPV--------LQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQ 386
P + + ++L + + +P G L EE
Sbjct: 10911 HPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEE---------------- 10954
Query: 387 PGLGSQDVV--SKAANRRIPMEGQRDSAFPKFESKPQS--QEVKENQTVKFRCEGLAVME 442
G+QD + N + G + +F K ++ + T+ C+ V
Sbjct: 10955 ---GTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPP 11011
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAEL 499
+++ V G +RG PVP W +G I ++ + + L
Sbjct: 11012 SVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVL 11071
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I++ L D G Y NA G + + +TV + P PT PI
Sbjct: 11072 TIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLD-------------VPGPPTGPI---- 11114
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPE 584
++D + MT +S PP +
Sbjct: 11115 ----NILDVTPEHMT--ISWQPPKD 11133
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 60/123 (48%), Gaps = 15/123 (12%)
Query: 12 ISKTSLSVDPSRVDSMPLTEAPAFILPPRN---------LCIKEGATAKFEGRVRGYPEP 62
I++T++++ P S P+T A +PPR L +K G + V G P P
Sbjct: 12770 IARTAVNISPPSEPSDPVTIL-AENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 12828
Query: 63 QVTWHRNGQPI--TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
V+W ++G + G + + R +L + +V+ +D G YT A N SG++ T++
Sbjct: 12829 TVSWKKDGTLLKPAEGIKMAMQ---RNLCTLELFSVNRKDSGDYTITAENSSGSKSATIK 12885
Query: 121 LTV 123
L V
Sbjct: 12886 LKV 12888
Score = 48.5 bits (114), Expect = 6e-05
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+ K G+ + GRP P VTW K L AR S+ + +L I V ++D G
Sbjct: 20784 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 20843
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDS 255
Y + NG G+ S+ +S++ LD+
Sbjct: 20844 KYILTIENGVGEPK-SSTVSVKVLDT 20868
Score = 48.5 bits (114), Expect = 6e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 1256 LTVVDKPDPPAG--TPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA 1313
+ +D PP P +D +S++L+W +GGS V Y IE+ W +
Sbjct: 23527 IVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTK-- 23584
Query: 1314 TCRSTSFNVQDLLPDH-----EYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVE 1367
C +T +++ H EY+FRV A N G EP++ V E E P E++
Sbjct: 23585 -CNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELD 23642
Score = 48.1 bits (113), Expect = 7e-05
Identities = 88/408 (21%), Positives = 158/408 (38%), Gaps = 69/408 (16%)
Query: 179 RFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNG 238
R I GRP P+V W + + + + S+ + +L + VN+ D G Y V N
Sbjct: 15382 RLFVPIKGRPAPEVKWARDHG--ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENS 15439
Query: 239 SGKASMSAELSIQGLDSANRSF---VRETKATNS---------DVRKEVTNVISKESKLD 286
SG S SA ++++ LD+ V+E T+ D ++ N I ++ +
Sbjct: 15440 SG--SKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKREST 15497
Query: 287 SLEAAAKSKNCSSP-------QRGGSPPWAANSQPQP----PRESKLESCKDSPRTAP-- 333
+ + NC Q G S + ++ + P E+ ES K S R P
Sbjct: 15498 RKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETA-ESVKASERPLPPG 15556
Query: 334 QTPVLQKTSSSITLQAARVQPEPRAPGLGVL---SPSGEERKRPAPPRPATFPTRQPGLG 390
+ ++ T +S++L + + + + LG + G ++ T T GL
Sbjct: 15557 KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATIT-GL- 15614
Query: 391 SQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSV 450
+ + + R+ + ++ + P+ S P + + + P+F +
Sbjct: 15615 ---IQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD---------------LVIPPAFKLL 15656
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEA--GVAELHIQDALPE 507
V+ G+D + G P P +TW + P+ Q R E+ + L I+DA E
Sbjct: 15657 FNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACRE 15716
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
D G Y N+ G+ + V V +K P PT P+
Sbjct: 15717 DVGHYVVKLTNSAGEAIETLNVIVLDK-------------PGPPTGPV 15751
Score = 48.1 bits (113), Expect = 7e-05
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 19/126 (15%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
+QLG PV+++ +E +PS+ E P F T VK + + GRP
Sbjct: 18883 RQLGVPVIARD---------IEIKPSV--ELP--FHT----FNVKAREQLKIDVPFKGRP 18925
Query: 189 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
Q V W K L+ + RV+VS + L I +++DVG Y V N +G S++ +
Sbjct: 18926 QATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAG--SITVPI 18983
Query: 249 SIQGLD 254
+I LD
Sbjct: 18984 TIIVLD 18989
Score = 48.1 bits (113), Expect = 7e-05
Identities = 35/150 (23%), Positives = 64/150 (42%), Gaps = 9/150 (6%)
Query: 106 CEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC--PPKF 163
C TN ELT + + + V ++ D S P+ T P I + PP+
Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFR----VFARNAADSVSEPSESTGPIIVKDDVEPPRV 19292
Query: 164 ATKL---GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
+ +VVK G++ + + I GRP P ++W K + ++ AR + + +L +
Sbjct: 19293 MMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTV 19352
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D G Y + N +G S++ +
Sbjct: 19353 KDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/158 (24%), Positives = 63/158 (39%), Gaps = 9/158 (5%)
Query: 1631 AVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPY 1690
AV + + S M S + KS L++ + + ++ A LE + E+
Sbjct: 25998 AVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEKSTTRK 26057
Query: 1691 FSKTI--------RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
T+ R + V EG +ARF C +G P P V W + Q + S Q+ +
Sbjct: 26058 IKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTK- 26116
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ IS V D+ Y+ NS G+ L ++
Sbjct: 26117 YKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154
Score = 47.8 bits (112), Expect = 1e-04
Identities = 38/132 (28%), Positives = 58/132 (43%), Gaps = 14/132 (10%)
Query: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FE 603
++ S+ F + + ++++G VT ++SG P P++ W +G I+ E + F
Sbjct: 1237 ISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFL 1296
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS------- 656
Q G + SL I V PED G YT A N G L V+ P +I
Sbjct: 1297 QDG-RASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLYVEPAAPLGAPTYIPTLEPVSR 1355
Query: 657 ----KPRSVTAS 664
PRSV+ S
Sbjct: 1356 IRSLSPRSVSRS 1367
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/101 (27%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV--WFKDDQSIRESRHFQIDY 1739
+++ KP+F K + L + A F+C++ DP +V W D + + + ++
Sbjct: 1650 DKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRM-I 1708
Query: 1740 DEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+E G CSL D TC+A N G +A LIV+
Sbjct: 1709 NEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVK 1749
Score = 47.8 bits (112), Expect = 1e-04
Identities = 44/182 (24%), Positives = 76/182 (41%), Gaps = 9/182 (4%)
Query: 1194 GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQ 1253
G P+T ++ ++++ KV + + T+ Q + + NK G +
Sbjct: 7018 GGSPLT-GYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Query: 1254 -----VNL-TVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1307
VN+ T PDPP D ++S+ L+W DGGS ++ Y +E +
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWR-DRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSD 7135
Query: 1308 TWKELAT-CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEV 1366
W T V L Y +RV+A+N G S+PS+ +E + E P+ +
Sbjct: 7136 KWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFL 7195
Query: 1367 EV 1368
+V
Sbjct: 7196 DV 7197
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
VT +G +V + G P P++ WL+DG L K++ + E+ TL +K + H
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPL-KESEFVRFSKTENKITLSIKNAKKEHG 21134
Query: 721 GQYEILLKNRVGECSCQVSLMLQNSSARALPRG 753
G+Y ++L N V C V + + + P+G
Sbjct: 21135 GKYTVILDNAV--CRIAVPITVITLGPPSKPKG 21165
Score = 47.8 bits (112), Expect = 1e-04
Identities = 35/144 (24%), Positives = 60/144 (41%), Gaps = 17/144 (11%)
Query: 506 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLP----VAPSKPTAPIFLQGLS 561
P D + +A NA+G +S S+ S ++ V P P + GL
Sbjct: 21423 PGDRYEFRIIARNAVGTIS----------PPSQSSGIIMTRDENVPPIVEFGPEYFDGLI 21472
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
+ G + + V G P P V W +G EI++ + SL +++ +
Sbjct: 21473 ---IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHR 21529
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQE 645
G YT EA N++G + + + VQ+
Sbjct: 21530 GVYTVEAKNASGSAKAEIKVKVQD 21553
Score = 47.4 bits (111), Expect = 1e-04
Identities = 117/571 (20%), Positives = 206/571 (36%), Gaps = 81/571 (14%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
E P F KL E C+++ V W K + PS + S+ ++
Sbjct: 5163 EADPYFTVKLHDKTAVEKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI 5220
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS---ANRSFVRET-----KATNS 269
L+I + D G Y C KA+++ E + ++ FV ET + +
Sbjct: 5221 LKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEP 5280
Query: 270 DVR---KEVTNVISKESKLDSLEAAAKS----KNCSSPQRGGSPPWAANSQPQPPRESK- 321
DV K ++ + +E K NC G AAN++ + K
Sbjct: 5281 DVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKE 5340
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
L +P + V +K + + +R +P+ G +G++R
Sbjct: 5341 LPLIFITPLS--DVKVFEKDEAKFECEVSR-EPKTFRWLKGTQEITGDDR---------- 5387
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
F + G V+ AA D A FE++ ++ + K EG+ +
Sbjct: 5388 FELIKDGTKHSMVIKSAA--------FEDEAKYMFEAE------DKHTSGKLIIEGIRLK 5433
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHI 501
+ P LKD E + V + + R+ W N Q + RS + +
Sbjct: 5434 FLTP-----LKDVTAKEKESAVFTVELSHDNI-RVKWFKNDQRLHTTRS--------VSM 5479
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
QD T+ L+ + Q+ A SE L V P F L
Sbjct: 5480 QDEGKTHSITFKDLSIDDTSQIRVEA--------MGMSSEAKLTVLEGD---PYFTGKLQ 5528
Query: 562 DLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDT 621
D ++ +V + ++S P V W +G EI+ S++ + G + L +++ D
Sbjct: 5529 DYTGVEKDEVILQCEISKADAP-VKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDI 5587
Query: 622 GTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 681
G YTC+ G +T L +++ + + SV ++ I+ D
Sbjct: 5588 GQYTCD----CGTDKTSGKLDIED----REIKLVRPLHSVEVMETETARFETEISEDDI- 5638
Query: 682 TVHWLRDGKALCKDTGHFEVLQNEDVFTLVL 712
+W G+AL + T E+ + + +LVL
Sbjct: 5639 HANWKLKGEALLQ-TPDCEIKEEGKIHSLVL 5668
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKE--LATCR 1316
+++P PP +SD SS+ L W DGGS + Y IE + W +
Sbjct: 6792 IERPSPPVNLT-SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVP 6850
Query: 1317 STSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDD 1371
++ V L ++Y +RV A N G S+PS+ T + EP ++ D
Sbjct: 6851 ELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKD 6905
Score = 47.4 bits (111), Expect = 1e-04
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 7/133 (5%)
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDL 563
+P++ T T L E A Q A V+ S S+ + +A + P + + S L
Sbjct: 12749 IPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLL 12808
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP---ED 620
V G+ V + V G P P V W +G ++ +E + Q +LC E+F +D
Sbjct: 12809 TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI---KMAMQRNLCTLELFSVNRKD 12865
Query: 621 TGTYTCEAWNSAG 633
+G YT A NS+G
Sbjct: 12866 SGDYTITAENSSG 12878
Score = 47.4 bits (111), Expect = 1e-04
Identities = 25/82 (30%), Positives = 36/82 (43%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
+ KE R I G+P P V+W KG PL RVSV L ++ + D G
Sbjct: 13496 LAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGK 13555
Query: 231 YTCLVVNGSGKASMSAELSIQG 252
YT + N +G + + + G
Sbjct: 13556 YTITLKNVAGTKEGTISIKVVG 13577
Score = 47.4 bits (111), Expect = 1e-04
Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
LT P+ LP I+ G K E V G P P ++W ++G+P+ R ++ T
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATST 17870
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
L I +++D GKYT ATN +G + + V
Sbjct: 17871 V-LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 47.4 bits (111), Expect = 1e-04
Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 1/119 (0%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
NA S S + E P + + + L + G + R ++G P P V
Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVT 21494
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
WFKD I + + +I D G+ SL + D D YT +A N+ G A ++ V+
Sbjct: 21495 WFKDGVEIEKRMNMEIT-DVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Score = 47.4 bits (111), Expect = 1e-04
Identities = 28/104 (26%), Positives = 44/104 (42%), Gaps = 4/104 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELA---TCRST 1318
P PP G P + + W DGG+ + +Y ++ + + W + T
Sbjct: 22743 PSPP-GIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDT 22801
Query: 1319 SFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEP 1362
V L+ +Y+FRV A+N G SEPS+ S + E P
Sbjct: 22802 RLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTP 22845
Score = 47.4 bits (111), Expect = 1e-04
Identities = 34/120 (28%), Positives = 56/120 (46%), Gaps = 5/120 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQ 63
V + S S++ ++P +P E + + + I+ GA+ + V G P P
Sbjct: 22923 VNVKGMSEYSESIAEIEPVERIEIPDLELADDL--KKTVTIRAGASLRLMVSVSGRPPPV 22980
Query: 64 VTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+TW + G + S R ++D L++ V+ D GKYT EA N SG + TV + V
Sbjct: 22981 ITWSKQGIDLAS--RAIIDT-TESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKV 23037
Score = 47.0 bits (110), Expect = 2e-04
Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 60/343 (17%)
Query: 919 KKKLPAENGSSSAETLNAKAVESSKPLSNAQPS--GPLKPVGNAKPAETLKPMGNAKPAE 976
++++ + +GS E + VES +S + S V K + +A ++
Sbjct: 4141 QEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSD 4200
Query: 977 TLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
K + KP E + +S E ++V V + G + P L
Sbjct: 4201 E-KQDESLKPSEEKEESSSESGTEEVAT-VKIQEAEGGLIKED--------GPMIHTPLV 4250
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED- 1095
D EG + L +++ + W K + + + Q+ + ++ I+K ED
Sbjct: 4251 DTVSEEGDIVHLTTSITN--AKEVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDH 4308
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
+G Y C A ND+G+ S ++TV K
Sbjct: 4309 QGEYVCEALNDSGKTATSAKLTV-----------------------------------VK 4333
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+ AP K E +V G + ++ + W K ++I ES+
Sbjct: 4334 RAAPVIKRKI----------EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKC 4383
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ +S+ S L IL + CG YT N+ GS LTV
Sbjct: 4384 SIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV 4426
Score = 47.0 bits (110), Expect = 2e-04
Identities = 100/477 (20%), Positives = 188/477 (39%), Gaps = 71/477 (14%)
Query: 683 VHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW-HAGQYEILLKNRVGECSCQVSLM 741
V+W + K + D F+ LQ+++ +TLV+ KV H G+Y N G+ + L
Sbjct: 4272 VNWYFENKLVPSDE-KFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLT 4330
Query: 742 LQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVR 801
+ +A + R EP ++ G + ++R W G+ + E D +R
Sbjct: 4331 VVKRAAPVIKRKIEPL---EVALGHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIR 4386
Query: 802 G--------VLKRRV-ETRQHTEEAIRQQE----VEQLDFRDLLGKKVSTKTLSEDDLKE 848
+L+ +V + ++T +A + L G+K K L E K
Sbjct: 4387 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVPGGEKKVRKLLPER--KP 4444
Query: 849 IPAEQMDFRANLQR---QVKPKTVSEEERKVHSP-----------QQVDFRSVLAKKGTS 894
P E++ ++ L++ + +PK ++ KV P ++V+ +V ++
Sbjct: 4445 EPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE--R 4502
Query: 895 KTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPL 954
K P P KVP KPA P LPA E A+ P +P+
Sbjct: 4503 KIPEPTKVPEIKPAIP-----------LPAPEPKPKPE---AEVKTIKPPPVEPEPTPIA 4548
Query: 955 KPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAG 1014
PV P K A E KP G P + + + ++ + + G
Sbjct: 4549 APV--TVPVVGKKAEAKAPKEEAAKPKG---PIKGVPKKTPSPIEAERRKLRPGSGGEKP 4603
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAE----GKKLLLQCQVSSDPPATII--WTLNGKT 1068
+ + + F ++++D+ + E G + +C VS P+T I W +G
Sbjct: 4604 PDEAPFTYQLKAVPLKFVKEIKDIILTESEFVGSSAIFECLVS---PSTAITTWMKDGSN 4660
Query: 1069 LKTT---KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
++ + +FI ++ L + ++ + D G Y CV + + + ++ V++ P
Sbjct: 4661 IRESPKHRFIADGKDRKLHIIDVQLS---DAGEYTCVLRLGNKEKTSTAKLVVEELP 4714
Score = 47.0 bits (110), Expect = 2e-04
Identities = 104/465 (22%), Positives = 165/465 (35%), Gaps = 67/465 (14%)
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKL-----GR 169
RQ TV+ EG+ K V + G P ET+P E A +L G
Sbjct: 8562 RQYTVKEIREGADYKLRVSAVNAAGEG-----PPGETQPVTVAEPQEPPAVELDVSVKGG 8616
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ + G+ R +TGRP P W K L RV + L I + D G
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKD-RVVIDNVGTKSELIIKDALRKDHG 8675
Query: 230 VYTCLVVNGSGKASMSAE----------LSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
Y N G +A L ++ + + + + D E+T I
Sbjct: 8676 RYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFI 8735
Query: 280 --SKESKLDS----LEAAAKSKNCSSPQRGGSPPWAANSQPQ----PPRESKLESCKD-- 327
K++K+ + +E + + G + ++ + PP E D
Sbjct: 8736 IERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPL 8795
Query: 328 SPRTAPQT-PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPP-----RPAT 381
P T+P+ ++T S+ITL EPR+ G + E++R P
Sbjct: 8796 GPPTSPERLTYTERTKSTITLD----WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL 8851
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
PT + + D + R+ + + P Q+ + T+K R
Sbjct: 8852 CPTTSFLVENLDE-HQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRL------ 8904
Query: 442 EVAPSFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA------ 494
SV D ++ G+ + V G P+P+I W N I+ +
Sbjct: 8905 -------SVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 8957
Query: 495 ---GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS 536
EL I A+ ED GTYT A N LG V + V V+++ S
Sbjct: 8958 RSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9002
Score = 47.0 bits (110), Expect = 2e-04
Identities = 109/532 (20%), Positives = 188/532 (35%), Gaps = 89/532 (16%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
L I+ G GR G P+P+V+W ++ + R + T +L D
Sbjct: 10331 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKT-TPATLALEKIKAKRSDS 10389
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
GKY N +G+R+ ++ V +G + D + +P +
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYM---VISWKPPL-----D 10441
Query: 162 KFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLEI 220
+K+ ++++ ++G+ W+ + + + +VS + + I
Sbjct: 10442 DGGSKITNYIIEKKEVGKD------------VWMPVTSASAKTTCKVSKLLEGKDYIFRI 10489
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--------DVR 272
H N G+ LV + SM A+ + D+ ++ V E ++ D
Sbjct: 10490 HAENL--YGISDPLVSD-----SMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGG 10542
Query: 273 KEVTNVISKESKLDSLEAAAKSKN----------------CSSPQRGGSPPWAANSQPQP 316
K +TN I ++ + S A +K+ C R + P P
Sbjct: 10543 KPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSP 10602
Query: 317 PRE---SKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGEERK 372
P + +K K SP P+ S +T Q R + G V G+E
Sbjct: 10603 PSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEW 10662
Query: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKF---------ESKPQSQ 423
R A P + P + + G RD KF ES P
Sbjct: 10663 RRANHTPESCP----------------ETKYKVTGLRDGQTYKFRVLAVNAAGESDPA-- 10704
Query: 424 EVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
V E VK R E ++ A ++ ++ + G L ++G P P++TW +
Sbjct: 10705 HVPEPVLVKDRLEPPELILDA----NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDR 10760
Query: 484 PIQY-ARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
AR ++L I++A ED G Y+ EN G + S V V +K
Sbjct: 10761 DAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDK 10812
Score = 47.0 bits (110), Expect = 2e-04
Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 58/370 (15%)
Query: 1042 EGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYK 1100
EG + C++ + D + W + L+ ++ ++ E + + ++ D G Y+
Sbjct: 25084 EGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYR 25143
Query: 1101 CVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK-KPAP 1159
C ND G+ ++ V + + RR T+KK K
Sbjct: 25144 CKVVNDYGEDSSYAELFVKGV-----REVYDYYCRR---------------TMKKIKRRT 25183
Query: 1160 KTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK--- 1216
T PP+ ++ GE+V +T TW K ++I+ ++ K
Sbjct: 25184 DTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYT 25243
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP----------- 1265
E+ + +LTI + + YT++ NK G + LTV P P
Sbjct: 25244 FESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLHPPPTDSTLRPMFKRL 25303
Query: 1266 -------AGTPCASDIRSSSL---TLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC 1315
G +IR S + TL W DG +IEI +
Sbjct: 25304 LANAECQEGQSVCFEIRVSGIPPPTLKW---EKDGQPLSLGPNIEIIHEGLDYY------ 25354
Query: 1316 RSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKE 1375
+ +++D LP+ +RV A N G++ ++ + K +E K + E +K+
Sbjct: 25355 ---ALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVERLRYKKQEFKSKEEHERHVQKQ 25411
Query: 1376 PEVDYRTVTI 1385
+ R I
Sbjct: 25412 IDKTLRMAEI 25421
Score = 46.2 bits (108), Expect = 3e-04
Identities = 74/344 (21%), Positives = 131/344 (38%), Gaps = 46/344 (13%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ + + +G A FE V G P P VTW + + + + + + G+ + +
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR--------F 144
++ ED G Y C+A N G EL V P +K+ +
Sbjct: 3635 VNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDFPQTPL 3694
Query: 145 SAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
PAVE S + AT + ++K + + +++ + L +PL
Sbjct: 3695 KGPAVEALDS-----EQEIATFVKDTILKAALITEENQQLSYEHIAKANELSSQLPLGAQ 3749
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS----GKASMSAELSIQGLDSANRSF 260
S+ E++ + + + C +NGS S L +Q + S ++F
Sbjct: 3750 ELQSILEQDKL--------TPESTREFLC--INGSIHFQPLKEPSPNLQLQIVQS-QKTF 3798
Query: 261 VR---------ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAAN 311
+ ET+A SD K + +S E +++SL + P+ G P
Sbjct: 3799 SKEGILMPEEPETQAVLSDTEKIFPSAMSIE-QINSLTVEPLKTLLAEPE-GNYP----Q 3852
Query: 312 SQPQPPRESKLESCKDSPRTAPQTPVLQKTS--SSITLQAARVQ 353
S +PP S L S + +P+ + T+ +TLQ Q
Sbjct: 3853 SSIEPPMHSYLTSVAEEV-LSPKEKTVSDTNREQRVTLQKQEAQ 3895
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
LP KE + + + ++G P P V+W + P+ + R ++ T +L+++
Sbjct: 13490 LPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNT-TLIVYDC 13548
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEG 125
+ D GKYT N +G ++ T+ + V G
Sbjct: 13549 QKSDAGKYTITLKNVAGTKEGTISIKVVG 13577
Score = 46.2 bits (108), Expect = 3e-04
Identities = 34/121 (28%), Positives = 53/121 (43%), Gaps = 14/121 (11%)
Query: 1648 SGRKSSTGSPTSPLNAEKLESE----EDVSQAFLEAVAEEKPHVKPYFSKTIRDLE-VVE 1702
S ++ + P+ P E++ E V + A + +K SK I L VVE
Sbjct: 26184 SPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQFLKAEASKEIAKLTCVVE 26243
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
S R EV W+KD + ++E+ HFQ Y DG L I+++ D +Y C
Sbjct: 26244 SSVLRAK---------EVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVC 26294
Query: 1763 K 1763
+
Sbjct: 26295 E 26295
Score = 45.8 bits (107), Expect = 4e-04
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 4/85 (4%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L+DV+V EG K +L+C+VS ++ W LN + +K + +G+ + I +
Sbjct: 2405 LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHAS 2464
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVD 1119
D G YK + G+ E +C ++V+
Sbjct: 2465 DEGPYKLI----VGRVETNCNLSVE 2485
Score = 45.8 bits (107), Expect = 4e-04
Identities = 26/79 (32%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
PHV+ F + + DL+V E ARF+C++ + +V WFKD I++ + + I +
Sbjct: 5875 PHVE--FLRPLTDLQVREKEMARFECEL-SRENAKVKWFKDGAEIKKGKKYDI-ISKGAV 5930
Query: 1745 CSLIISDVCGDDDAKYTCK 1763
L+I+ DD+A+Y+C+
Sbjct: 5931 RILVINKCLLDDEAEYSCE 5949
Score = 45.8 bits (107), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGV 496
++E P + L + G+ ++ V+G PVPR+TW +G I+ + T G
Sbjct: 21460 IVEFGPEYFDGL---IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGS 21516
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE 533
L ++DA + G YT A+NA G V V +
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQD 21553
Score = 45.8 bits (107), Expect = 4e-04
Identities = 88/439 (20%), Positives = 162/439 (36%), Gaps = 71/439 (16%)
Query: 263 ETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQ-----RGGSPPWAA------- 310
E S ++EVT + E + + + A + + S+ + R SP +
Sbjct: 25732 EKSRKKSRRQREVTEITEIEEEYEISKHAQRESSSSASRLLRRRRSLSPTYIELMRPVSE 25791
Query: 311 --NSQPQPPRESKLESCKDSP---RTAPQTP--VLQKTSSSITLQAARVQPEPRAPGLGV 363
S+PQP E + ++ + SP RT P++P V + S S ++AR R +
Sbjct: 25792 LIRSRPQPAEEYEDDTERRSPTPERTRPRSPSPVSSERSLSRFERSARFDIFSRYESMKA 25851
Query: 364 L---SPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKP 420
+ E + +P T + + + + R+P GQ +SKP
Sbjct: 25852 ALKTQKTSERKYEVLSQQPFTLDH------APRITLRMRSHRVPC-GQNTRFILNVQSKP 25904
Query: 421 QSQ--------EVKENQTVKF-RCEGLAVME--------------VAPSFSSVLKDCAVI 457
++ E++E+ + + G+ +E V ++ D A +
Sbjct: 25905 TAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATL 25964
Query: 458 E--GQDFVLQCSVR-GTPVPRITWLLNGQPIQYARST------CEAGVAELHIQDALPED 508
+ G D+ S R VPR + + YA S+ EA + ++ + E
Sbjct: 25965 DVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTET 26024
Query: 509 HGTYTCLAENALGQVSCSAWV--TVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+ + +A ++ +A ++ EK ++RK + L A L + V
Sbjct: 26025 RESLSSYEHSASAEMKSAALEEKSLEEKSTTRKIKTTL--------AARILTKPRSMTVY 26076
Query: 567 DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 626
+G + G P P V WL G + S + + I V D G Y+
Sbjct: 26077 EGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQVTTTKYKSTFEISSVQASDEGNYSV 26136
Query: 627 EAWNSAGEVRTQAVLTVQE 645
NS G+ + LT+Q+
Sbjct: 26137 VVENSEGKQEAEFTLTIQK 26155
Score = 45.4 bits (106), Expect = 5e-04
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 8/98 (8%)
Query: 1683 EKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDED 1742
E H++ F K I+D++V+E A F+C++ PD V W KDDQ ++ + +I ++
Sbjct: 3008 EARHIE--FRKHIKDIKVLEKKRAMFECEV-SEPDITVQWMKDDQELQITDRIKIQKEKY 3064
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ L+I D KYT A G TA+L VE
Sbjct: 3065 VH-RLLIPSTRMSDAGKYTVVA----GGNVSTAKLFVE 3097
Score = 45.4 bits (106), Expect = 5e-04
Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 1/83 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
+ G + + + V G P P + W+ +G ++++ + E+ T L I+E +D G Y
Sbjct: 17826 IQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKY 17885
Query: 625 TCEAWNSAG-EVRTQAVLTVQEP 646
T A NSAG +V+ +++P
Sbjct: 17886 TVTATNSAGTATENLSVIVLEKP 17908
Score = 45.1 bits (105), Expect = 6e-04
Identities = 57/219 (26%), Positives = 87/219 (39%), Gaps = 16/219 (7%)
Query: 1159 PKTPPKAAMPPQIIQFPED-QKVRAGESVELFGKVTGTQPITCTWM--KFRKQIQESEHM 1215
P PP A P++ + +R E G I W+ K R I +
Sbjct: 22340 PFVPPSAPTRPEVYHVSANAMSIRWEEPYH-----DGGSKIIGYWVEKKERNTILWVKEN 22394
Query: 1216 KVENSENGSKLTILAARQEH-CGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
KV E K+T L E+ Y L + +A + + D P G P +D+
Sbjct: 22395 KVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAP-GRPEVTDV 22453
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIE---IWDSANKTWKE--LATCRSTSFNVQDLLPDH 1329
S+++L W +YDGGS V Y IE + + + W + F V L
Sbjct: 22454 TRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGD 22513
Query: 1330 EYKFRVRAINVYGT-SEPSQESELTTVGEKPEEPKDEVE 1367
Y+FRV A N G S+ S+ + T ++ PK E++
Sbjct: 22514 TYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELD 22552
Score = 44.7 bits (104), Expect = 8e-04
Identities = 28/112 (25%), Positives = 46/112 (41%), Gaps = 4/112 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATC----RS 1317
P P G P D+ S+++L W +DGGS + Y +E W T
Sbjct: 12692 PVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQ 12751
Query: 1318 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVS 1369
+ L +Y+FR A S PS+ S+ T+ + P+ ++ V+
Sbjct: 12752 EEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12803
Score = 44.7 bits (104), Expect = 8e-04
Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN-EDVFTLVLKKVQPWHAGQYE 724
G SV + I+G P PT+ W +D K L T ++N D+ ++++K ++G YE
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKEL--QTNALVCVENTTDLASILIKDADRLNSGCYE 20447
Query: 725 ILLKNRVGECSCQVSLML 742
+ L+N +G S + + +
Sbjct: 20448 LKLRNAMGSASATIRVQI 20465
Score = 44.3 bits (103), Expect = 0.001
Identities = 183/961 (19%), Positives = 338/961 (35%), Gaps = 154/961 (16%)
Query: 180 FSCKITGRPQPQVTWLKG--NVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
F+C I + P + W KG +P +P+ + + L+I +D+ Y +
Sbjct: 4828 FACDIA-KDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEG 4886
Query: 238 GSGKASMS-AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
A ++ E ++ L + E ++ + D + I + KL E S
Sbjct: 4887 KRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEAD-IPGQWKLKG-ELLRPSPT 4944
Query: 297 CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP 356
C GG + L ++ TA T + ++ L+ V
Sbjct: 4945 CEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPERR 5004
Query: 357 RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQR------D 410
+A VL+ P D++ + I +G++ D
Sbjct: 5005 QARFECVLTREANVIWSKGP----------------DIIKSSDKFDIIADGKKHILVIND 5048
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 470
S F + + EV+ +T L V + F S L+D V EG+ C +
Sbjct: 5049 SQFD--DEGVYTAEVEGKKT----SARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSH 5102
Query: 471 TPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
+ + W N + +R+ + + H + + E L +S
Sbjct: 5103 EKM-HVVWFKNDAKLHTSRTVLISSEGKTHKLE-----------MKEVTLDDIS-QIKAQ 5149
Query: 531 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
V E S+ + + L P F L D ++ ++T+ +VS + P V W +
Sbjct: 5150 VKELSSTAQLKVL-------EADPYFTVKLHDKTAVEKDEITLKCEVSKDVP--VKWFKD 5200
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN--SAGEVRTQA-VLTVQEPH 647
G EI S + + G + L I++ +D G Y C+ + V +A ++ V++P
Sbjct: 5201 GEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPL 5260
Query: 648 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVH--WLRDGKALCKDTGHFEVLQNE 705
G + F+ + L + P VH W G+ L E++++
Sbjct: 5261 YGVEV-FVGETAHFEIELSE-------------PDVHGQWKLKGQPLTASPD-CEIIEDG 5305
Query: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS-----LMLQNSSARALPR-------- 752
L+L Q G+ N + +V + S + +
Sbjct: 5306 KKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECE 5365
Query: 753 -GREPASCEDLCGGGVGADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETR 811
REP + L G + G DR+ ++ G + ++ ED + +
Sbjct: 5366 VSREPKTFRWLKGT---QEITGDDRFELIKDG--TKHSMVIKSAAFEDEAKYMFEAED-- 5418
Query: 812 QHTE-----EAIRQQEVEQLDFRDLLGKK----VSTKTLSEDDLKEIPAEQMDFRANLQR 862
+HT E IR + + L +D+ K+ V T LS D+++ + + N QR
Sbjct: 5419 KHTSGKLIIEGIRLKFLTPL--KDVTAKEKESAVFTVELSHDNIR------VKWFKNDQR 5470
Query: 863 QVKPKTVS-EEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKK 921
++VS ++E K HS + F+ L+ TS+ V + + K
Sbjct: 5471 LHTTRSVSMQDEGKTHS---ITFKD-LSIDDTSQIRVEAMG-------------MSSEAK 5513
Query: 922 LPAENGSS--SAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLK 979
L G + + + VE + + + S PV K + +KP NA
Sbjct: 5514 LTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNAV------ 5567
Query: 980 PMGNAKPDENLKSASKEE---LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQ 1036
+K+ K+ LKK +K+D+ GT + + + + L
Sbjct: 5568 ----------IKADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLH 5617
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
V V E + + ++S D W L G+ L T + +EG + S+ + +
Sbjct: 5618 SVEVMETETARFETEISED-DIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQT 5676
Query: 1097 G 1097
G
Sbjct: 5677 G 5677
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS--LVIHAVHEE 99
L +K G T +F +RG P P W +G I + + ++ FS L I
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVE---TDNFSSVLTIKNCLRR 11079
Query: 100 DRGKYTCEATNGSGARQVTVELTV 123
D G+Y +N +G++ V V LTV
Sbjct: 11080 DTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 2/123 (1%)
Query: 532 HEKKSSRKSEYLLPV-APSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
+EK S + +PV A P F + V+ G + + V G P P V W +
Sbjct: 15628 NEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD 15687
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEPHDG 649
++++ + E L I++ ED G Y + NSAGE + T V+ + +P
Sbjct: 15688 NVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPP 15747
Query: 650 TQP 652
T P
Sbjct: 15748 TGP 15750
Score = 44.3 bits (103), Expect = 0.001
Identities = 81/396 (20%), Positives = 141/396 (35%), Gaps = 56/396 (14%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV++ R I GRP+P+V W K L A++ V+ + +L I V + D G
Sbjct: 18620 VVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVT--SSFTMLVIDNVTRFDSG 18677
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSF---VRETKATN---------SDVRKEVTN 277
Y + N SG S +A ++++ LDS + +RE K + D ++TN
Sbjct: 18678 RYNLTLENNSG--SKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITN 18735
Query: 278 VISKESKLDSLEAAAKSKNCSSP-------QRGGSPPWAANSQPQPPRESKLESCKDSPR 330
I ++ + A + NC+ Q G S + + + E+ +
Sbjct: 18736 YIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKV 18795
Query: 331 TAPQTPVLQKTSSSITLQAARVQPE-------PRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ P P + T +T A ++ E + G V + K + T
Sbjct: 18796 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLE 18855
Query: 384 TRQPGL--GSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
GL G + V AA R P + E+K + + F +
Sbjct: 18856 ATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVI---ARDIEIKPSVELPFHTFNVKAR 18912
Query: 442 EVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAE 498
E + +G P + W +GQ ++ + V
Sbjct: 18913 E------------------QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTS 18954
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
L I++A ED GTY N+ G ++ + V ++
Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 18990
Score = 43.9 bits (102), Expect = 0.001
Identities = 23/81 (28%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
PPK ++ +K G+ R + G+P P W KG + S+ ++V + + +L
Sbjct: 12402 PPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILI 12460
Query: 220 IHGVNQDDVGVYTCLVVNGSG 240
I V + D G Y+ N SG
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSG 12481
Score = 43.9 bits (102), Expect = 0.001
Identities = 112/518 (21%), Positives = 191/518 (36%), Gaps = 68/518 (13%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLD-CGIRGTFSLVIHAVHEEDRG 102
I+ G+ + V G PEP++ W + + + + L G R T VI D G
Sbjct: 22562 IRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRAT--AVIKFCDRSDSG 22619
Query: 103 KYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR----FSAPAVETRPSIWGE 158
KYT N SG + V+V + V S G+ VS+ ++ +S P + I
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDS-PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHY 22678
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQP-----QVTWLKGNVPLQPSARVSVSEKN 213
+ T V+ EG+ S +T + +V + P P + +N
Sbjct: 22679 IVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARN 22738
Query: 214 GMQVLEIHGVNQD-DVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNS--- 269
+ G+ ++ G ++ ++ E+S +D + +R T+
Sbjct: 22739 SFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVV 22798
Query: 270 -DVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKD- 327
D R +VT+++ + C R + A NS+P S SC++
Sbjct: 22799 YDTRLKVTSLM---------------EGCDYQFRVTAVNAAGNSEPS--EASNFISCREP 22841
Query: 328 ----SPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEER-------KRPAP 376
P +AP+ V+ T SI+L + + +G + E+ A
Sbjct: 22842 SYTPGPPSAPR--VVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNAT 22899
Query: 377 PRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE 436
R F +G + AA + ++G + S+ + E + V+ R E
Sbjct: 22900 IRNTEFTVPDLKMGQKYSFRVAA---VNVKGMSE----------YSESIAEIEPVE-RIE 22945
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 496
+ +E+A + K + G L SV G P P ITW G +
Sbjct: 22946 -IPDLELA---DDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTES 23001
Query: 497 AELHIQDALPE-DHGTYTCLAENALGQVSCSAWVTVHE 533
L I D + D G YT AEN G+ S + V V++
Sbjct: 23002 YSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYD 23039
Score = 43.5 bits (101), Expect = 0.002
Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 23/135 (17%)
Query: 4 VKLVASSHISKTSLSVDP---SRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYP 60
VK V ++ +SK S +V P R D P + F+ ++EG +++G P
Sbjct: 9594 VKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFME------VEEGTNVNIVAKIKGVP 9647
Query: 61 EPQVTWHR-------NGQPI---TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
P +TW + N +P+ T + ++D T +LVI D G YT A N
Sbjct: 9648 FPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD----DTCTLVIPQSRRSDTGLYTITAVN 9703
Query: 111 GSGARQVTVELTVEG 125
G + L V G
Sbjct: 9704 NLGTASKEMRLNVLG 9718
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
+ +KT++++EV E A F+C++ + P +W K+ I S F+I + LII
Sbjct: 2837 HITKTMKNIEVPETKTASFECEVSHFNVPS-MWLKNGVEIEMSEKFKIVVQGKLH-QLII 2894
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
+ +D A+YT N AT T I+ T + EE++
Sbjct: 2895 MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKD 2938
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE-------DGNCSLIIS 1750
+EV EG+ KI+G P P + WFK +++ + YD D C+L+I
Sbjct: 9629 MEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKE-PVLYDTHVNKLVVDDTCTLVIP 9687
Query: 1751 DVCGDDDAKYTCKAVNSLGEAT 1772
D YT AVN+LG A+
Sbjct: 9688 QSRRSDTGLYTITAVNNLGTAS 9709
Score = 43.1 bits (100), Expect = 0.002
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V+ GQ R ++ GRP+P +TW K L RV + + L+I + D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDS 287
Y N SG A SA +++ LD + K TN V KE IS E+ LD+
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV--LDRPGP--CQNLKVTN--VTKE-NCTISWENPLDN 11531
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V E K + P + + G R + + G P P W K + + S H +
Sbjct: 12391 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAV 12450
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ D + LII DV D Y+ A NS G T +++V
Sbjct: 12451 -HKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 1662 NAEKLESEEDVSQAFLEAVAEEKP---HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDP 1718
NA + SE S + A E P + P + TI V G + + D I G P P
Sbjct: 16020 NAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTI---VVHAGESFKVDADIYGKPIP 16076
Query: 1719 EVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+ W K DQ + + +I D SL + D D Y KA N GE + T +
Sbjct: 16077 TIQWIKGDQELSNTARLEIK-STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVK 16135
Query: 1779 V 1779
V
Sbjct: 16136 V 16136
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 3/93 (3%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFN 1321
P PP S + S+TL W DGGS + Y IE + + W +
Sbjct: 19486 PSPPTSLEITS-VTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLR 19544
Query: 1322 VQD--LLPDHEYKFRVRAINVYGTSEPSQESEL 1352
V+ L EY++RV A N G S PS+ S L
Sbjct: 19545 VKSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19577
Score = 42.7 bits (99), Expect = 0.003
Identities = 57/243 (23%), Positives = 94/243 (38%), Gaps = 58/243 (23%)
Query: 1025 QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII--WTLNGKTLKTT-KFIILSQEG 1081
+G F ++LQD+ V E L+C VS P I W N LK+ K+ I S+ G
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVS---PENIEGKWYHNDVELKSNGKYTITSRRG 2273
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
+++++ ED+G Y V
Sbjct: 2274 RQ-NLTVKDVTKEDQGEYSFV--------------------------------------- 2293
Query: 1142 PPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCT 1201
+ G ++ +K KP P I+Q DQKV G+ V+L KV+ + +
Sbjct: 2294 --IDGKKTTCKLKMKPRPIA---------ILQGLSDQKVCEGDIVQLEVKVS-LESVEGV 2341
Query: 1202 WMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
WMK +++Q S+ + + + L I +E G Y+ + S +V++ VD
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDV 2401
Query: 1262 PDP 1264
P
Sbjct: 2402 ITP 2404
Score = 42.7 bits (99), Expect = 0.003
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 10/98 (10%)
Query: 1691 FSKTIRDLEVVE----GSAARFDCKIEGYPDPEVV-WFKDDQSIRES-RHFQIDYDEDGN 1744
F K I+D+ + E GS+A F+C + P + W KD +IRES +H I +D
Sbjct: 4620 FVKEIKDIILTESEFVGSSAIFECLVS--PSTAITTWMKDGSNIRESPKHRFIADGKDRK 4677
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+I DV D +YTC E T TA+L+VE +
Sbjct: 4678 LHII--DVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/143 (23%), Positives = 57/143 (39%), Gaps = 12/143 (8%)
Query: 117 VTVELTVEGSFAKQLGQ-PVVSKTLGDRFSAPAVETRPSIWGE--------CPPKFATKL 167
+ + TV G Q + V++K S P+ T P + PKF
Sbjct: 17079 IETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDT- 17137
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDD 227
+VV G+ R + G+P P + WL+G+ ++ SAR + + +L + + D
Sbjct: 17138 --IVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17195
Query: 228 VGVYTCLVVNGSGKASMSAELSI 250
G Y N +G S + +
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKV 17218
Score = 42.4 bits (98), Expect = 0.004
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 990 LKSASKEELK-KDVKNDVNCKRGHAGTTDNEKRSESQGTAPA----------FKQKLQDV 1038
+KS K +++ K + + +N + H G + + T+ A F++ ++D+
Sbjct: 2962 IKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEFRKHIKDI 3021
Query: 1039 HVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGL 1098
V E K+ + +C+VS +P T+ W + + L+ T I + +E + + I D G
Sbjct: 3022 KVLEKKRAMFECEVS-EPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGK 3080
Query: 1099 YKCVAKNDAGQAE 1111
Y VA + A+
Sbjct: 3081 YTVVAGGNVSTAK 3093
Score = 42.4 bits (98), Expect = 0.004
Identities = 21/72 (29%), Positives = 34/72 (47%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++++ G R + GRP P++TW K NV L+ + + + L VN+ D G
Sbjct: 13206 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 13265
Query: 230 VYTCLVVNGSGK 241
Y + N GK
Sbjct: 13266 KYILTLENSCGK 13277
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 2/77 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + + V G P P V W +++++ +FE T L I E D+G Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLT 14642
Query: 628 AWNSAGEVRTQAVLTVQ 644
A N GEV V+T+Q
Sbjct: 14643 ARNIVGEVGD--VITIQ 14657
Score = 42.4 bits (98), Expect = 0.004
Identities = 37/148 (25%), Positives = 60/148 (40%), Gaps = 25/148 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAG--VAELHIQDALPE 507
KD V+ G+ F + + G P+P I W+ Q + AR ++ L ++DA+
Sbjct: 16053 KDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV 16112
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK--- 564
D G Y A+N G+ S VTV+ K R P P P+ + G++ K
Sbjct: 16113 DSGNYILKAKNVAGERS----VTVNVKVLDR---------PGPPEGPVVISGVTAEKCTL 16159
Query: 565 -----VMDGSQVTMTVQVSGNPPPEVIW 587
+ DG + V ++W
Sbjct: 16160 AWKPPLQDGGSDIINYIVERRETSRLVW 16187
Score = 42.4 bits (98), Expect = 0.004
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 5/95 (5%)
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
+P VKP FS V G + + I G P P + W KD ++++ + D
Sbjct: 16732 EPDVKPAFSS----YSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT-DSLD 16786
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELI 1778
+L I + DD +Y N +G+ T + E++
Sbjct: 16787 LTTLSIKETHKDDGGQYGITVANVVGQKTASIEIV 16821
Score = 42.4 bits (98), Expect = 0.004
Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726
+ + I G P TV+W +DG+ L K+T V ++ V +L +K+ G YE+
Sbjct: 18913 EQLKIDVPFKGRPQATVNWRKDGQTL-KETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 18971
Query: 727 LKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
+ N G + +++++ + P + SC+ +
Sbjct: 18972 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSI 19007
Score = 42.4 bits (98), Expect = 0.004
Identities = 34/130 (26%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 520 LGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK----VMDGSQVTMTV 575
+GQ V+ K S SE + + P + L+ DLK + G+ + + V
Sbjct: 22912 MGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRLMV 22971
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
VSG PPP + W G I + + + L + +V D G YT EA N +G+
Sbjct: 22972 SVSGRPPPVITWSKQG--IDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23029
Query: 636 RTQAVLTVQE 645
++ V +
Sbjct: 23030 SATVLVKVYD 23039
Score = 42.0 bits (97), Expect = 0.005
Identities = 30/89 (33%), Positives = 47/89 (52%), Gaps = 7/89 (7%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG-KTLKTTKFIILSQEGSLCSVSIE 1089
F + L+D V EG +L+C+VS + A + W NG + LK+ K+ I++ +G + + I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEVSREN-AKVKWFKNGTEILKSKKYEIVA-DGRVRKLVIH 5847
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
PED Y C DA + SC + V
Sbjct: 5848 DCTPEDIKTYTC----DAKDFKTSCNLNV 5872
Score = 42.0 bits (97), Expect = 0.005
Identities = 49/222 (22%), Positives = 76/222 (34%), Gaps = 44/222 (19%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT 88
L E F N+ + E T K V P +V W++ + I GR+ + R
Sbjct: 5962 LEEEAVFTKNLANIEVSETDTIKLVCEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKR 6020
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
LVI H ED G Y C + +V V
Sbjct: 6021 I-LVIQNAHLEDAGNYNCRLPSSRTDGKVKVH---------------------------- 6051
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
E +F +K + + EG+ F C I+ P V W + + L+ +
Sbjct: 6052 ---------ELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRDDKTLESGDKYD 6101
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
V +VL + D+G Y +V G A +A L++
Sbjct: 6102 VIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTV 6139
Score = 42.0 bits (97), Expect = 0.005
Identities = 26/93 (27%), Positives = 39/93 (41%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P+ + ++ + L V G+ V + G P P W +G+EI+ E + E
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11070
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
L I+ DTG Y N+AG LTV
Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T G +V + + G P PTV W +DG L K ++ ++ TL L V +
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866
Query: 721 GQYEILLKNRVGECSCQVSL 740
G Y I +N G S + L
Sbjct: 12867 GDYTITAENSSGSKSATIKL 12886
Score = 42.0 bits (97), Expect = 0.005
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV+ G R GRP P W K + L S R + + L + N++D G
Sbjct: 21871 VVRAGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENCNRNDAGK 21928
Query: 231 YTCLVVNGSGKASMSAELSI 250
YT V N SG S++ + +
Sbjct: 21929 YTLTVENNSGSKSITFTVKV 21948
Score = 42.0 bits (97), Expect = 0.005
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 13/142 (9%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL-KVMDGSQ 570
+ LA+NA G +S + T + + EY AP K L G DL + GS
Sbjct: 22517 FRVLAKNAAGVISKGSEST---GPVTCRDEY----APPKAELDARLHG--DLVTIRAGSD 22567
Query: 571 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 630
+ + V G P P++IW E+ E + G + + I+ D+G YT N
Sbjct: 22568 LVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKN 22627
Query: 631 SAGEVRTQAVLTVQEPHDGTQP 652
++G T+AV + + D P
Sbjct: 22628 ASG---TKAVSVMVKVLDSPGP 22646
Score = 42.0 bits (97), Expect = 0.005
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
T D ++ P E + G+ V ++ G + G+P+P++ W KG+
Sbjct: 22539 TCRDEYAPPKAELDARLHGDL----------VTIRAGSDLVLDAAVGGKPEPKIIWTKGD 22588
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDS 255
L +VS+ I ++ D G YT V N SG ++S + + LDS
Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV--LDS 22643
Score = 41.6 bits (96), Expect = 0.007
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 7/108 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + ++EV E + C++ P EV+W+K D+ I E+ ++I E L+I
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQ 6025
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA-ELIVETMEEGEG----EGEEEE 1793
+ +D Y C+ +S + EL E + + + EGE+ E
Sbjct: 6026 NAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAE 6073
Score = 41.6 bits (96), Expect = 0.007
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQV 64
A+ ISK S S P + + E P + P+ + + G T + E V G P P +
Sbjct: 17103 AAGAISKPSDSTGP--ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTI 17160
Query: 65 TWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
W R + I R C I+ T L++ D G+Y A+N +G++ V +
Sbjct: 17161 EWLRGDKEIEESAR----CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNV 17216
Query: 122 TV 123
V
Sbjct: 17217 KV 17218
Score = 41.6 bits (96), Expect = 0.007
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
++VK G + GRP P V W K + L+ A V ++ L I N++D G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSR--TSLTIENANRNDSG 19756
Query: 230 VYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKE 274
YT + N AS++ L ++ LD+ T T DV KE
Sbjct: 19757 KYTLTIQNVLSAASLT--LVVKVLDTPG----PPTNITVQDVTKE 19795
Score = 41.6 bits (96), Expect = 0.007
Identities = 34/133 (25%), Positives = 51/133 (38%), Gaps = 9/133 (6%)
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
TCE Q +E V K L PV T+G + T + P
Sbjct: 21020 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPV---TIGPITVKELIITPEVDLSDIPG--- 21073
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
+V V+ G G+P+P ++WLK +PL+ S V S+ L I
Sbjct: 21074 ---AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAK 21130
Query: 225 QDDVGVYTCLVVN 237
++ G YT ++ N
Sbjct: 21131 KEHGGKYTVILDN 21143
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/98 (27%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI--RESRHFQIDYDEDGN 1744
+ P D+ + EG C G P PEV W + I +E F I+ + D
Sbjct: 26830 IPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIE-NTDDL 26888
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
+LII DV D YT N G + T + + ++
Sbjct: 26889 TTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIRSI 26926
Score = 41.2 bits (95), Expect = 0.009
Identities = 24/96 (25%), Positives = 43/96 (44%)
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+C P + ++V EG+ P P V+W K ++ S R+++ +
Sbjct: 7887 DCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAH 7946
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
LE+ + D G+YT + N G A+ S + + GL
Sbjct: 7947 LEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 7982
Score = 41.2 bits (95), Expect = 0.009
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-RSTCEAG--VAELHI 501
P+ D VIEG+ + R PVP ++W +G+ ++ + R T + A L +
Sbjct: 7890 PTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEV 7949
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTV 531
++ D G YT EN LG + S V V
Sbjct: 7950 PKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 41.2 bits (95), Expect = 0.009
Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K I L V G+ RF I G P P W D I+ H+ ++ D + L I +
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV-LTIKNC 11076
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D +Y N+ G T L V
Sbjct: 11077 LRRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 41.2 bits (95), Expect = 0.009
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G++ ++ I G P P V W +DGK L + E+ TLV+K
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDG 18279
Query: 721 GQYEILLKNRVGECSCQVSL 740
GQY + L N G S +++
Sbjct: 18280 GQYILKLSNVGGTKSIPITV 18299
Score = 41.2 bits (95), Expect = 0.009
Identities = 26/85 (30%), Positives = 34/85 (40%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L+L V P IIWT K L + + L G + I+ D G
Sbjct: 22560 VTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSG 22619
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y KN +G S V V D+P
Sbjct: 22620 KYTLTVKNASGTKAVSVMVKVLDSP 22644
Score = 40.8 bits (94), Expect = 0.012
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Query: 535 KSSRKSEYLLPVAPSK-PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
K SR +E + V + P + ++ L+ L V G+++ + V+G P P++ W
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMI 7233
Query: 594 IQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+++ + E + ++ I + DTGTY EA N G R AV+ V
Sbjct: 7234 LKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG--RATAVVEV 7281
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/87 (26%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K + L V G+ + G P+P++ W K D +++ + I+ + ++ I D
Sbjct: 7198 KLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIE-NVPKKSTVTIVDS 7256
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y +AVN G AT E+ V
Sbjct: 7257 KRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 40.8 bits (94), Expect = 0.012
Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 1262 PDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKEL-ATCRSTSF 1320
P PP + I ++ L W DGGS + +Y +E D K W+ + T + T
Sbjct: 7587 PSPPRWLEVIN-ITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7645
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSE 1345
V L Y FRV A N G S+
Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSD 7670
Score = 40.8 bits (94), Expect = 0.012
Identities = 24/91 (26%), Positives = 37/91 (40%), Gaps = 1/91 (1%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P IL P + IK G + E V G P P W + + + + + L+
Sbjct: 12402 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI-LI 12460
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I V +D G Y+ A N SG +++ V
Sbjct: 12461 IKDVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 40.8 bits (94), Expect = 0.012
Identities = 20/81 (24%), Positives = 39/81 (48%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VV G+ + I G+P P + W+KG+ L +AR+ + + L + + D G
Sbjct: 16056 IVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSG 16115
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y N +G+ S++ + +
Sbjct: 16116 NYILKAKNVAGERSVTVNVKV 16136
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 1/78 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
++ G K E + G P+P +TW ++G P+ R + + T +L I H++D G+
Sbjct: 16744 VQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT-TLSIKETHKDDGGQ 16802
Query: 104 YTCEATNGSGARQVTVEL 121
Y N G + ++E+
Sbjct: 16803 YGITVANVVGQKTASIEI 16820
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
++P + G + + + G P P + W KD + ++++ ++ + +
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVE-ETATSTV 17871
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + DD KYT A NS G AT +IV
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 40.8 bits (94), Expect = 0.012
Identities = 23/74 (31%), Positives = 33/74 (44%)
Query: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
Q+ + V G P V W +G ++E+ + T SL I+E ED GTY
Sbjct: 18914 QLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVS 18973
Query: 630 NSAGEVRTQAVLTV 643
NSAG + + V
Sbjct: 18974 NSAGSITVPITIIV 18987
Score = 40.8 bits (94), Expect = 0.012
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 642 TVQEPHDGTQPWFISK----PRS---------VTASLGQSVLISCAIAGDPFPTVHWLRD 688
+V EP + T P + PR + G+ + I+ IAG P P + W +D
Sbjct: 19270 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19329
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
G + ++ E++ ++ L +K GQY + LKN G S V+
Sbjct: 19330 GIEI-EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVN 19379
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F+K + D V EG+ A +C++ + +V WFK+ I +S+ ++I D L+I
Sbjct: 5790 FTKPLEDQTVEEGATAVLECEV-SRENAKVKWFKNGTEILKSKKYEIVADGRVR-KLVIH 5847
Query: 1751 DVCGDDDAKYTCKA 1764
D +D YTC A
Sbjct: 5848 DCTPEDIKTYTCDA 5861
Score = 40.4 bits (93), Expect = 0.016
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 1/75 (1%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ ++ G T + RV+G PEP +TW + G+ + R L + L I D
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDL-PRVELQIKEAVRADH 11479
Query: 102 GKYTCEATNGSGARQ 116
GKY A N SG Q
Sbjct: 11480 GKYIISAKNSSGHAQ 11494
Score = 40.4 bits (93), Expect = 0.016
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---EAGVAELHIQDALPEDHGTYTCL 515
GQ + V+G P P ITW G+ + + + EL I++A+ DHG Y
Sbjct: 11426 GQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHGKYIIS 11485
Query: 516 AENALGQVSCSAWVTVHEK 534
A+N+ G SA V V ++
Sbjct: 11486 AKNSSGHAQGSAIVNVLDR 11504
Score = 40.0 bits (92), Expect = 0.020
Identities = 33/111 (29%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 20 DPSRVDSMPLT----EAPAFILPP---RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP 72
DP+ V L E P IL R IK G T + ++G P P+VTW + +
Sbjct: 10702 DPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRD 10761
Query: 73 ITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ R +D G+ + +A H ED G Y+ N +G++ V+V++ V
Sbjct: 10762 APTKAR--IDVTPVGSKLEIRNAAH-EDGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 2/120 (1%)
Query: 529 VTVHEKKSSRKSEYLLP-VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 587
V V+EK S +P VA P S V G + + V +SG P P + W
Sbjct: 16707 VAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITW 16766
Query: 588 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE-VRTQAVLTVQEP 646
+G ++++ + +L I+E +D G Y N G+ + ++T+ +P
Sbjct: 16767 TKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKP 16826
Score = 40.0 bits (92), Expect = 0.020
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 18/115 (15%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQ--YARSTCEAGVAE--LHIQDALP 506
KD V+ G+ FVL+ +RG P+P + W +G+ ++ AR ++ + + L ++D +
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y N G S V V ++ P P P+ + G++
Sbjct: 18277 TDGGQYILKLSNVGGTKSIPITVKVLDR-------------PGPPEGPLKVTGVT 18318
Score = 40.0 bits (92), Expect = 0.020
Identities = 20/73 (27%), Positives = 29/73 (39%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G V + + G PPP V W + + + E + L I +V DTG Y
Sbjct: 20789 GEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILT 20848
Query: 628 AWNSAGEVRTQAV 640
N GE ++ V
Sbjct: 20849 IENGVGEPKSSTV 20861
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/107 (30%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT---FSLVIHAVHEEDRGK 103
G AKF ++ P + W + G+ I + C IR + SL I D G+
Sbjct: 4351 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDK----CSIRSSKYISSLEILRTQVVDCGE 4406
Query: 104 YTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
YTC+A+N G+ T LTV G+ V K L +R P E
Sbjct: 4407 YTCKASNEYGSVSCTATLTV----TVPGGEKKVRKLLPERKPEPKEE 4449
Score = 39.7 bits (91), Expect = 0.027
Identities = 33/101 (32%), Positives = 47/101 (46%), Gaps = 8/101 (7%)
Query: 1668 SEEDVSQAFLEAV---AEEKPHV---KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1721
S +D SQ +EA+ +E K V PYF+ ++D VE C+I D V
Sbjct: 5494 SIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISK-ADAPVK 5552
Query: 1722 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
WFKD + I+ S++ I D LI+ D +YTC
Sbjct: 5553 WFKDGKEIKPSKNAVIKADGKKR-MLILKKALKSDIGQYTC 5592
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/110 (26%), Positives = 45/110 (40%), Gaps = 8/110 (7%)
Query: 21 PSR----VDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI 73
PSR + ++ EAP L + L +K G + V G PEP++TW + +
Sbjct: 7175 PSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMIL 7234
Query: 74 TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
R ++ + ++ I D G Y EA N G VE+ V
Sbjct: 7235 KQDKRITIE-NVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 39.7 bits (91), Expect = 0.027
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+VVK G RF I G P P W ++ +V N VL I + D G
Sbjct: 11023 LVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11082
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y V N +G +++ L++
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTV 11103
Score = 39.7 bits (91), Expect = 0.027
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 19/124 (15%)
Query: 446 SFSSVLKDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAG----VAELH 500
S +D V+ G+ F L+ V G P+P I WL + I+ + + CE A L
Sbjct: 17129 SMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEES-ARCEIKNTDFKALLI 17187
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
++DA+ D G Y A N G S V V ++ P P P+ + G+
Sbjct: 17188 VKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDR-------------PGPPEGPVQVTGV 17234
Query: 561 SDLK 564
+ K
Sbjct: 17235 TSEK 17238
Score = 39.7 bits (91), Expect = 0.027
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 6/123 (4%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
+++ A + + + P V EAP L + + ++ G +A+ +G P
Sbjct: 17496 IRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRP 17555
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P++TW R T + ++ G+ T L I D GKY + N SG++ V
Sbjct: 17556 TPEITWSREEGEFTD--KVQIEKGVNYT-QLSIDNCDRNDAGKYILKLENSSGSKSAFVT 17612
Query: 121 LTV 123
+ V
Sbjct: 17613 VKV 17615
Score = 39.7 bits (91), Expect = 0.027
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
V + G L L VS PP I W+ G L + I ++ SL + ++K D G
Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSL--LIVDKVNRYDAG 23016
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAP 1122
Y A+N +G+ + V V D P
Sbjct: 23017 KYTIEAENQSGKKSATVLVKVYDTP 23041
Score = 39.3 bits (90), Expect = 0.035
Identities = 65/327 (19%), Positives = 119/327 (36%), Gaps = 37/327 (11%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT-GHFEVLQNEDVFTL 710
P F +SV G + I+G P P V W RDG+ + T ++ ++ L
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKL 65
Query: 711 VLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGAD 770
+ V ++G+Y + N G+ + L+++ +A P + L +
Sbjct: 66 TIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETA-------PPNFVQRL--QSMTVR 116
Query: 771 GGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQH------TEEAIRQQEVE 824
G R G P + DG +++ L ++ E
Sbjct: 117 QGSQVRLQVRVTGIPTPVVKFY--RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174
Query: 825 QLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDF 884
++ + +G+ ST L +E+PA++ + Q+ + E+K+ + D
Sbjct: 175 SVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVS-TAQISESRQTRIEKKIEA--HFDA 231
Query: 885 RSV----LAKKGTSKTPVPEKVPPPKPATPDFRS----VLGGKKKLPAENGSSSAETLNA 936
RS+ + G + +P K PP P P RS + K +L + S
Sbjct: 232 RSIATVEMVIDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIR---- 287
Query: 937 KAVESSKPLSNAQPSGPLKPVGNAKPA 963
S P+ + + P PV + PA
Sbjct: 288 ---HSPSPVRHVRAPTP-SPVRSVSPA 310
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/102 (26%), Positives = 38/102 (37%), Gaps = 1/102 (0%)
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI 1737
E V + P KP D+ V+EG P P V W KD + ++ S +
Sbjct: 7879 ENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTM 7938
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
D + L + D YT N LG AT + + V
Sbjct: 7939 KNDHI-SAHLEVPKSVRADAGIYTITLENKLGSATASINVKV 7979
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 7/126 (5%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE--AGVAELHIQDALP 506
SV ++ G+ + V G PVP W + R + +EL I+DAL
Sbjct: 8612 SVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALR 8671
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM 566
+DHG Y A N+ G +A V V + +L + P + L SD +
Sbjct: 8672 KDHGRYVITATNSCGSKFAAARVEVFDVPGP-----VLDLKPVVTNRKMCLLNWSDPEDD 8726
Query: 567 DGSQVT 572
GS++T
Sbjct: 8727 GGSEIT 8732
Score = 39.3 bits (90), Expect = 0.035
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 13/87 (14%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKA--LCKDTGH-------FEVLQNEDVFTLVLKKVQ 716
G + I I G P P W DGKA KD H E +N V +++ + +
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSV--IIIPECK 9385
Query: 717 PWHAGQYEILLKNRVGE--CSCQVSLM 741
H G+Y I KN+ G+ +C+V +M
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVM 9412
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 9/144 (6%)
Query: 599 DFHFEQRGT--QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFIS 656
D HFE G H + + G ++ E S G + + V P P +
Sbjct: 15998 DTHFEVTGLVEDHRYEFRVIARNAAGVFS-EPSESTGAITARD--EVDPPRISMDPKYKD 16054
Query: 657 KPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQ 716
++ G+S + I G P PT+ W++ + L +T E+ + +L +K
Sbjct: 16055 ---TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKSTDFATSLSVKDAV 16110
Query: 717 PWHAGQYEILLKNRVGECSCQVSL 740
+G Y + KN GE S V++
Sbjct: 16111 RVDSGNYILKAKNVAGERSVTVNV 16134
Score = 38.9 bits (89), Expect = 0.045
Identities = 56/243 (23%), Positives = 87/243 (35%), Gaps = 50/243 (20%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G+V A + I+ L+V +D F +P +++ + E A+FE + E
Sbjct: 4967 GEVLYQALNAITTAILTVKEIELD---------FAVPLKDVTVPERRQARFECVLTR--E 5015
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W + I S +F + + LVI+ +D G YT E
Sbjct: 5016 ANVIWSKGPDIIKSSDKFDIIADGKKHI-LVINDSQFDDEGVYTAE-------------- 5060
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
VEG K R + KF + L VKEG+ F
Sbjct: 5061 -VEG------------KKTSARLFVTGIRL----------KFMSPLEDQTVKEGETATFV 5097
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C+++ + V W K + L S V +S + LE+ V DD+ V S
Sbjct: 5098 CELS-HEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSST 5156
Query: 242 ASM 244
A +
Sbjct: 5157 AQL 5159
Score = 38.9 bits (89), Expect = 0.045
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
FA L V V E + RF C +T + V W KG ++ S + + +L I+
Sbjct: 4991 FAVPLKDVTVPERRQARFECVLTR--EANVIWSKGPDIIKSSDKFDIIADGKKHILVIND 5048
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
DD GVYT V GK + SA L + G+
Sbjct: 5049 SQFDDEGVYTAEV---EGKKT-SARLFVTGI 5075
Score = 38.9 bits (89), Expect = 0.045
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ V G + + +V G P P++ W G + + Q + L I+E D G
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRADHG 11480
Query: 623 TYTCEAWNSAGEVRTQAVLTV 643
Y A NS+G + A++ V
Sbjct: 11481 KYIISAKNSSGHAQGSAIVNV 11501
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 1/124 (0%)
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLR 687
A N+ G + V E + P I P +T G+ + I + G P PT W +
Sbjct: 12378 ARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKW-K 12436
Query: 688 DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
G+ + H V + + L++K V +G Y + +N G + ++ +++ ++
Sbjct: 12437 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12496
Query: 748 RALP 751
P
Sbjct: 12497 PPQP 12500
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/103 (28%), Positives = 45/103 (43%), Gaps = 10/103 (9%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
SV A G+ V + G P PTV W +D K L D + + + L + +V
Sbjct: 20783 SVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSD-ARYSIENTDSSSLLTIPQVTRND 20841
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDL 762
G+Y + ++N VGE SS ++ PA+C+ L
Sbjct: 20842 TGKYILTIENGVGE---------PKSSTVSVKVLDTPAACQKL 20875
Score = 38.9 bits (89), Expect = 0.045
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 16/100 (16%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L+ +G P P I+WL +G P+ ++ R + L I++A E G YT +
Sbjct: 21081 GHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVI 21140
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPI 555
+NA+ +++ V L P PSKP PI
Sbjct: 21141 LDNAVCRIAVPITVIT-----------LGP--PSKPKGPI 21167
Score = 38.5 bits (88), Expect = 0.059
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 3/114 (2%)
Query: 1146 GTESDAT-VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
G E+ T + PAP P PP ++ ++ V GESV L ++G T TW +
Sbjct: 875 GREAKVTETARVPAPVEIP--VTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYR 932
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
QI+ S ++ ++L I A E G +T N+ G+ L V
Sbjct: 933 EDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986
Score = 38.5 bits (88), Expect = 0.059
Identities = 23/93 (24%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 545 PVAPSKPTAP----IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF 600
PV ++P P + + +++M G + + V+G P P +W E+ + +
Sbjct: 8595 PVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL-DKDRV 8653
Query: 601 HFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+ GT+ L I++ +D G Y A NS G
Sbjct: 8654 VIDNVGTKSELIIKDALRKDHGRYVITATNSCG 8686
Score = 38.5 bits (88), Expect = 0.059
Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTW--HRNGQPITSGGRFLLDCGIRGT-FSLVIHAVHE 98
L +K G T + E VRG P P+V W ++ +T R +D + FSL
Sbjct: 11714 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLT--KAKR 11771
Query: 99 EDRGKYTCEATNGSGA 114
D GKY ATN +G+
Sbjct: 11772 SDGGKYVVTATNTAGS 11787
Score = 38.5 bits (88), Expect = 0.059
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
PAF L + G K + G P P VTWH++ P+ R + L
Sbjct: 15651 PAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE-STENNSLLT 15709
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I ED G Y + TN +G T+ + V G + + D +
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLS----- 15764
Query: 153 PSIWGECPPKF 163
WG PPK+
Sbjct: 15765 ---WG--PPKY 15770
Score = 38.5 bits (88), Expect = 0.059
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD VV G R + + G P P + W + D+ I ES +I + D LI+ D
Sbjct: 17135 RDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIK-NTDFKALLIVKDAIR 17193
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y +A N G
Sbjct: 17194 IDGGQYILRASNVAG 17208
Score = 38.5 bits (88), Expect = 0.059
Identities = 22/83 (26%), Positives = 37/83 (44%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ K G I+GRP P+VTW + L+ + RVS++ L + + D G
Sbjct: 22160 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSG 22219
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y + N +G + S + + G
Sbjct: 22220 RYFLTLENTAGVKTFSVTVVVIG 22242
Score = 38.1 bits (87), Expect = 0.078
Identities = 58/270 (21%), Positives = 103/270 (38%), Gaps = 43/270 (15%)
Query: 472 PVPRITWL-LNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT 530
PV W+ +N +PI+ + E GV +P+ A NA+G
Sbjct: 7828 PVGTEKWMRVNSRPIKDLKFKVEEGV--------VPDKEYVLRVRAVNAIGV-------- 7871
Query: 531 VHEKKSSRKSEYLLPVAPS-KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLH 589
+ S SE ++ P KPT + D+ V++G ++++ V P P V W
Sbjct: 7872 ---SEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSWHK 7925
Query: 590 NGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA-VLTVQEPHD 648
+G E++ S+ + L + + D G YT N G V + P
Sbjct: 7926 DGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP-- 7983
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDP------FPTVHWLRDGKALCKDTGHFEVL 702
P K +T S SC + +P P +H++ + + + T + V+
Sbjct: 7984 --GPCKDIKASDITKS-------SCKLTWEPPEFDGGTPILHYVLERREAGRRT-YIPVM 8033
Query: 703 QNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
E+ + +K + P + + N+VG
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVG 8063
Score = 37.7 bits (86), Expect = 0.10
Identities = 28/92 (30%), Positives = 39/92 (42%), Gaps = 7/92 (7%)
Query: 551 PTAPIFLQGLSD-LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDF------HFE 603
PT + L D +KV G V + V+G P P++ W N I++ D
Sbjct: 8898 PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVS 8957
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
+ + L I + ED GTYT A N G V
Sbjct: 8958 RSEAKTELSIPKAVREDKGTYTVTASNRLGSV 8989
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/73 (27%), Positives = 33/73 (45%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V++K G+ R ++GRP P + W K L+ +A++ + + L + D G
Sbjct: 14974 VILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSG 15033
Query: 230 VYTCLVVNGSGKA 242
YT N G A
Sbjct: 15034 AYTLTATNPGGFA 15046
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPRN---LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
+AP L P+ + + G T E +RG P P V W ++G+ + + R + I+
Sbjct: 18206 DAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQ 18265
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
T +LV+ D G+Y + +N G + + + + V
Sbjct: 18266 KT-TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 13/99 (13%)
Query: 548 PSKPTAPIFLQG-------LSDLKVMD------GSQVTMTVQVSGNPPPEVIWLHNGNEI 594
PS+ T PI ++ + D+K D G + + ++G P P + W +G EI
Sbjct: 19274 PSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEI 19333
Query: 595 QESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG 633
+E L +++ DTG Y N AG
Sbjct: 19334 EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAG 19372
Score = 37.7 bits (86), Expect = 0.10
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 562 DLKVMDGSQVTMTV--------QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
DL + G+QVT+ + G P P + WL +G ++ESE F + + +L I
Sbjct: 21067 DLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSI 21126
Query: 614 QEVFPEDTGTYT 625
+ E G YT
Sbjct: 21127 KNAKKEHGGKYT 21138
Score = 37.7 bits (86), Expect = 0.10
Identities = 20/83 (24%), Positives = 38/83 (45%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLY 1099
+ G+ L ++ V P + W +G ++ + ++ S+ + A + RG+Y
Sbjct: 21473 IKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVY 21532
Query: 1100 KCVAKNDAGQAECSCQVTVDDAP 1122
AKN +G A+ +V V D P
Sbjct: 21533 TVEAKNASGSAKAEIKVKVQDTP 21555
Score = 37.7 bits (86), Expect = 0.10
Identities = 43/188 (22%), Positives = 76/188 (40%), Gaps = 8/188 (4%)
Query: 595 QESEDFHFEQRGT-QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT---VQEPH-DG 649
Q+ DF E T Q + ++ + + + +A N AG + + ++EP +
Sbjct: 22089 QKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEP 22148
Query: 650 TQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT 709
T + +T G I I+G P P V W + L K+T + +D T
Sbjct: 22149 TADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-KETDRVSITTTKDRTT 22207
Query: 710 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARAL-PRGREPASCED-LCGGGV 767
L +K +G+Y + L+N G + V++++ P S E + G
Sbjct: 22208 LTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGE 22267
Query: 768 GADGGGSD 775
DGGG++
Sbjct: 22268 PKDGGGTE 22275
Score = 37.7 bits (86), Expect = 0.10
Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 5/105 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
GS T+ V +SG P P+V W ++E++ + +L +++ D+G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22224
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
N+AG V+T +V V G ++ P V++ +S ++S
Sbjct: 22225 LENTAG-VKTFSVTVVVIGRPGP----VTGPIEVSSVSAESCVLS 22264
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/83 (28%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS-LIISDVCGDD 1756
++++ G R + G P P VW K++ + + R + D G S LII D D
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDR---VVIDNVGTKSELIIKDALRKD 8673
Query: 1757 DAKYTCKAVNSLGEATCTAELIV 1779
+Y A NS G A + V
Sbjct: 8674 HGRYVITATNSCGSKFAAARVEV 8696
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/123 (26%), Positives = 49/123 (39%), Gaps = 6/123 (4%)
Query: 624 YTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ +A N+AG + A + + P I + G +V I I G PFPT+
Sbjct: 9592 FRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTL 9651
Query: 684 HWLR------DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQ 737
W + D K H L +D TLV+ + + G Y I N +G S +
Sbjct: 9652 TWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKE 9711
Query: 738 VSL 740
+ L
Sbjct: 9712 MRL 9714
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+T +GQ++ I + G P P + W ++GK L ++ +++Q+ L +K+
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK-RVDLIQDLPRVELQIKEAVRADH 11479
Query: 721 GQYEILLKNRVG 732
G+Y I KN G
Sbjct: 11480 GKYIISAKNSSG 11491
Score = 37.4 bits (85), Expect = 0.13
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNG---QPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 515
G + L +V G P+P ++W +G +P + + + + L + +D G YT
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872
Query: 516 AENALGQVSCSAWVTVHEK 534
AEN+ G S + + V +K
Sbjct: 12873 AENSSGSKSATIKLKVLDK 12891
Score = 37.4 bits (85), Expect = 0.13
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 9/125 (7%)
Query: 19 VDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
VDP R+ P + + + G + K + + G P P + W + Q +++ R
Sbjct: 16041 VDPPRISMDPKYKD--------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTAR 16092
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ T SL + D G Y +A N +G R VTV + V G V+S
Sbjct: 16093 LEIKSTDFAT-SLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISG 16151
Query: 139 TLGDR 143
++
Sbjct: 16152 VTAEK 16156
Score = 37.4 bits (85), Expect = 0.13
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 9/116 (7%)
Query: 1671 DVSQAFLEAVAEEKPHVKPYF---SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
D S + +A+E+ +P F S+ + L V G++ G P P V+W K D
Sbjct: 19670 DPSDSSDPQIAKEREE-EPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDT 19728
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+R + D SL I + +D KYT N L A+ T L+V+ ++
Sbjct: 19729 DLRTRAYVD---TTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLT--LVVKVLD 19779
Score = 37.4 bits (85), Expect = 0.13
Identities = 24/100 (24%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 38 PPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVH 97
P + ++ G+ K + + G P P+VT R+G P+ + RF + ++ +
Sbjct: 19985 PSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAE-NLTINLKESV 20043
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
D G+Y A N SG + + + V G V+S
Sbjct: 20044 TADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083
Score = 37.4 bits (85), Expect = 0.13
Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 1/85 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+S+ I + G P P V W +DG + K + E+ +L ++ H G Y +
Sbjct: 21476 GESLRIKALVQGRPVPRVTWFKDGVEIEKRM-NMEITDVLGSTSLFVRDATRDHRGVYTV 21534
Query: 726 LLKNRVGECSCQVSLMLQNSSARAL 750
KN G ++ + +Q++ + +
Sbjct: 21535 EAKNASGSAKAEIKVKVQDTPGKVV 21559
Score = 37.0 bits (84), Expect = 0.17
Identities = 87/433 (20%), Positives = 147/433 (33%), Gaps = 79/433 (18%)
Query: 1009 KRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1068
+ H G + + P + V V EG+ +C+V+ P + W LNG+
Sbjct: 1775 RMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL 1834
Query: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP--ASEN 1126
++ +K + +G + + I D G K A+N G E ++ + S
Sbjct: 1835 IRKSKRFRVRYDG-IHYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVL 1893
Query: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+APE RP+ + + + +P T K + + + +KV ES
Sbjct: 1894 RRAPE---PRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKV-PEESE 1949
Query: 1187 ELFGKVTGT------QPITCTWMKFRKQIQESEHM-------------------KVENSE 1221
EL K + IT +K RK+ + E + K +E
Sbjct: 1950 ELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAE 2009
Query: 1222 NGSKLTI---------LAARQEHCGCYTLLVENKLG-SRQAQVNLTVVDKPDPPAGTPCA 1271
G K+TI L+ E + + +G A + VV KPDP
Sbjct: 2010 EG-KITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPEC----- 2063
Query: 1272 SDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRSTSFNVQDLLPDHEY 1331
WY + IE D W E C ++D+ +
Sbjct: 2064 ----------EWYKN---------GVKIERSDRIYWYWPEDNVCELV---IRDVTAEDSA 2101
Query: 1332 KFRVRAINVYGTSEPS-----QESELTTVGEKPEE----PKDEVEVSDDDEKEPEVDYRT 1382
V+AIN+ G + Q +L T ++ ++ KD + + + EP V +
Sbjct: 2102 SIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKW 2161
Query: 1383 VTINTEQKVSDFY 1395
E D Y
Sbjct: 2162 YKDGMEVHEGDKY 2174
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/76 (30%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + VSG PPP V W N NE ++ E S+ I+ G Y+
Sbjct: 10042 GGVIRIIAYVSGKPPPTVTW--NMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10099
Query: 628 AWNSAGEVRTQAVLTV 643
A N AGE + ++ V
Sbjct: 10100 AKNEAGERKKTIIVDV 10115
Score = 37.0 bits (84), Expect = 0.17
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQ-SIRESRHFQIDYDED-GNCSLIIS 1750
T RD+ V G R +++G P+P++ W K+ + +RE R +D +D L I
Sbjct: 11416 TCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKR---VDLIQDLPRVELQIK 11472
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTA 1775
+ D KY A NS G A +A
Sbjct: 11473 EAVRADHGKYIISAKNSSGHAQGSA 11497
Score = 37.0 bits (84), Expect = 0.17
Identities = 29/107 (27%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1680 VAEEKPHVKPYFSKTIRDLE------VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1733
V E+ VK K + DL+ V G R + + G P PEV W KD + +R
Sbjct: 11690 VKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTR 11749
Query: 1734 HFQIDYDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
++ D + S ++ D KY A N+ G A + V
Sbjct: 11750 SPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 37.0 bits (84), Expect = 0.17
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G ++ + V G P P W +E+ S + + L I++V +D+G
Sbjct: 12411 ITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSG 12470
Query: 623 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWF 654
Y+ A NS+G + + V + QP F
Sbjct: 12471 YYSLTAENSSGTDTQKIKVVVMDAPGPPQPPF 12502
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 3/72 (4%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
+ + G + R I+G P PEV W K D IR++ + SL++ +V D
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDV---TSSFTSLVLDNVNRYDS 16511
Query: 1758 AKYTCKAVNSLG 1769
KYT NS G
Sbjct: 16512 GKYTLTLENSSG 16523
Score = 37.0 bits (84), Expect = 0.17
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1689 PYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
P + EVV+ G++ + I G P P + W+KDD+ ++ + ++ D
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD-LA 20431
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
S++I D + Y K N++G A+ T
Sbjct: 20432 SILIKDADRLNSGCYELKLRNAMGSASAT 20460
Score = 37.0 bits (84), Expect = 0.17
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V + G + I+G+P P + W K + LQ +A V V + + I ++ + G
Sbjct: 20385 VKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSG 20444
Query: 230 VYTCLVVNGSGKASMSAELSIQGLD 254
Y + N G A SA + +Q LD
Sbjct: 20445 CYELKLRNAMGSA--SATIRVQILD 20467
Score = 36.6 bits (83), Expect = 0.23
Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 3/108 (2%)
Query: 143 RFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ 202
RF A E R + PK T +VV G+ P+ + W K N PL
Sbjct: 6485 RFIAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLS 6544
Query: 203 PSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ +E+ ++LE + D G Y ++ N GKA L +
Sbjct: 6545 TKTIDTTAEQTSFRILE---AKKGDKGRYKIVLQNKHGKAEGFINLKV 6589
Score = 36.6 bits (83), Expect = 0.23
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 172 VKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSV---SEKNGMQV-----LEIHGV 223
V+EG KI G P P +TW K P +P + V + N + V L I
Sbjct: 9631 VEEGTNVNIVAKIKGVPFPTLTWFKAP-PKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQS 9689
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSIQG 252
+ D G+YT VN G AS L++ G
Sbjct: 9690 RRSDTGLYTITAVNNLGTASKEMRLNVLG 9718
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V+V+ G R + GRP P+VTW K + + V + M L I +DD G
Sbjct: 12119 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGID-NVVRKGQVDLVDTMAFLVIPNSTRDDSG 12177
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y+ +VN +G+ ++ + +
Sbjct: 12178 KYSLTLVNPAGEKAVFVNVRV 12198
Score = 36.6 bits (83), Expect = 0.23
Identities = 37/151 (24%), Positives = 56/151 (37%), Gaps = 10/151 (6%)
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT- 574
A+N G +S + T + K EY P PT L + G + +
Sbjct: 13853 AKNTAGAISAPSEST---ETIICKDEYEAPTIVLDPTIK------DGLTIKAGDTIVLNA 13903
Query: 575 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGE 634
+ + G P P+ W G +I+ S+ T L I+ +D G YT A N G
Sbjct: 13904 ISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGT 13963
Query: 635 VRTQAVLTVQEPHDGTQPWFISKPRSVTASL 665
+TV + P IS + A+L
Sbjct: 13964 KVEHVKVTVLDVPGPPGPVEISNVSAEKATL 13994
Score = 36.6 bits (83), Expect = 0.23
Identities = 18/66 (27%), Positives = 29/66 (43%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + VSG PPP + W +G E++ + + +L ++ D+G YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT 15038
Query: 628 AWNSAG 633
A N G
Sbjct: 15039 ATNPGG 15044
Score = 36.6 bits (83), Expect = 0.23
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%)
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
V GS + + + +SG P P+V +G ++ + F+ E ++ ++E D G Y
Sbjct: 19991 VRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRY 20050
Query: 625 TCEAWNSAGEVRTQA-VLTVQEPHDGTQPWFIS 656
A NS+G + ++ + P T P IS
Sbjct: 20051 EITAANSSGTTKAFINIVVLDRPGPPTGPVVIS 20083
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 1674 QAFLEAVAEEKPHVKPYFSKTIRDLEVVE---GSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
+AF + +E P ++P T +++ GS D I G P P+V W ++ ++
Sbjct: 22134 EAFSSVIIKE-PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLK 22192
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
E+ I +D +L + D D +Y N+ G T + ++V
Sbjct: 22193 ETDRVSITTTKD-RTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVV 22240
Score = 36.2 bits (82), Expect = 0.29
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 8/106 (7%)
Query: 1007 NCKRGHAGTTD----NEKRSESQGTAP---AFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059
NC+ G D N K S P + L+DV V G+ C++S +
Sbjct: 5670 NCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYED-IP 5728
Query: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
+ W L GK L+ + ++ EG + ++++ ED G + AK+
Sbjct: 5729 VEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKD 5774
Score = 36.2 bits (82), Expect = 0.29
Identities = 19/81 (23%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
++ + G++ + + G P PT+ WLR K + +++ E+ + L++K
Sbjct: 17137 TIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI-EESARCEIKNTDFKALLIVKDAIRID 17195
Query: 720 AGQYEILLKNRVGECSCQVSL 740
GQY + N G S V++
Sbjct: 17196 GGQYILRASNVAGSKSFPVNV 17216
Score = 36.2 bits (82), Expect = 0.29
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW 718
++VT G S+ + +++G P P + W + G L + E L++ KV +
Sbjct: 22957 KTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDL---ASRAIIDTTESYSLLIVDKVNRY 23013
Query: 719 HAGQYEILLKNRVGECSCQV 738
AG+Y I +N+ G+ S V
Sbjct: 23014 DAGKYTIEAENQSGKKSATV 23033
Score = 35.8 bits (81), Expect = 0.38
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P T L V +EG + + IT + V W N + + + L I
Sbjct: 4243 PMIHTPLVDTVSEEGDIVHLTTSITNAKE--VNWYFENKLVPSDEKFKCLQDQNTYTLVI 4300
Query: 221 HGVNQDD-VGVYTCLVVNGSGKASMSAELSI 250
VN +D G Y C +N SGK + SA+L++
Sbjct: 4301 DKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4331
Score = 35.8 bits (81), Expect = 0.38
Identities = 37/186 (19%), Positives = 66/186 (35%), Gaps = 32/186 (17%)
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAP 147
T S ++ + E ++ +A N G + ++ L V + D P
Sbjct: 8854 TTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNV---------------VIQDDEVPP 8898
Query: 148 AVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS--- 204
++ R S+ G+ + VK G+ +TG P P++ W K ++
Sbjct: 8899 TIKLRLSVRGDT----------IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDA 8948
Query: 205 ---ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF- 260
+ VS L I ++D G YT N G + + + S R+
Sbjct: 8949 LQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLA 9008
Query: 261 VRETKA 266
V + KA
Sbjct: 9009 VTDIKA 9014
Score = 35.8 bits (81), Expect = 0.38
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G +V I G P PT W DG + K H+ V + L +K G+Y+I
Sbjct: 11028 GTTVRFPAIIRGVPVPTAKWTTDGSEI-KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQI 11086
Query: 726 LLKNRVGECSCQVSL 740
+ N G + V L
Sbjct: 11087 TVSNAAGSKTVAVHL 11101
Score = 35.8 bits (81), Expect = 0.38
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 5/97 (5%)
Query: 31 EAPAFILPPR---NLCIKEGATAKFEG-RVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
EAP +L P L IK G T + G P P+ +W + G+ I +
Sbjct: 13877 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 13936
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ + +A + D G+YT ATN G + V++TV
Sbjct: 13937 SSMLTIKYATRK-DAGEYTITATNPFGTKVEHVKVTV 13972
Score = 35.8 bits (81), Expect = 0.38
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
I+ G + + ++G P P+V W + I ++D T SLV+ V+ D GK
Sbjct: 16457 IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFT-SLVLDNVNRYDSGK 16513
Query: 104 YTCEATNGSGARQVTVELTV 123
YT N SG + V + V
Sbjct: 16514 YTLTLENSSGTKSAFVTVRV 16533
Score = 35.8 bits (81), Expect = 0.38
Identities = 25/91 (27%), Positives = 41/91 (45%), Gaps = 3/91 (3%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P+ LP +K K + +G P+ V W ++GQ + R + T SL
Sbjct: 18898 PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-SLS 18956
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
I +ED G Y +N +G+ +TV +T+
Sbjct: 18957 IKEASKEDVGTYELCVSNSAGS--ITVPITI 18985
Score = 35.8 bits (81), Expect = 0.38
Identities = 18/58 (31%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 1713 EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
+G P P V W KD++++ + I+ + D + L I V +D KY N +GE
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVGE 20855
Score = 35.8 bits (81), Expect = 0.38
Identities = 20/106 (18%), Positives = 44/106 (41%), Gaps = 2/106 (1%)
Query: 1015 TTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK- 1073
+T ++ +G P + D+ + EGK L + C + +P + W+ G+ + + +
Sbjct: 26818 STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQ 26877
Query: 1074 -FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ L ++ I +D GLY N+ G + + +
Sbjct: 26878 GRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923
Score = 35.4 bits (80), Expect = 0.50
Identities = 47/231 (20%), Positives = 82/231 (35%), Gaps = 56/231 (24%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + L ++ V+E + L C+VS P A +IW + + T + EG + I+
Sbjct: 5968 FTKNLANIEVSETDTIKLVCEVSK-PGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQN 6026
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESD 1150
A ED G Y C R P S +D
Sbjct: 6027 AHLEDAGNYNC---------------------------------RLPSS--------RTD 6045
Query: 1151 ATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQ 1210
VK + + I P++ ++ GE E ++ + W + K ++
Sbjct: 6046 GKVKVH---------ELAAEFISKPQNLEILEGEKAEFVCSIS-KESFPVQWKRDDKTLE 6095
Query: 1211 ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
+ V L + A + G Y ++V G+ +A +LTV++K
Sbjct: 6096 SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAAAHLTVIEK 6142
Score = 35.4 bits (80), Expect = 0.50
Identities = 16/82 (19%), Positives = 37/82 (45%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
++ ++ G+ + + +G+P+P+V+W K + R + LE + D
Sbjct: 10330 KLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDS 10389
Query: 229 GVYTCLVVNGSGKASMSAELSI 250
G Y +V N +G ++++
Sbjct: 10390 GKYCVVVENSTGSRKGFCQVNV 10411
Score = 35.4 bits (80), Expect = 0.50
Identities = 25/96 (26%), Positives = 37/96 (38%), Gaps = 4/96 (4%)
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL--HNGNEIQESEDFHFEQRGT 607
KP + L G+ L V G + + V G P PEV W + ++ S + R
Sbjct: 11703 KPVLDLKLSGV--LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRAD 11760
Query: 608 QHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+ + D G Y A N+AG A + V
Sbjct: 11761 SSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 35.4 bits (80), Expect = 0.50
Identities = 31/122 (25%), Positives = 47/122 (38%), Gaps = 9/122 (7%)
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 571
+ +A+NA G +S + T + K E LP P + + V G
Sbjct: 17096 FRVIAKNAAGAISKPSDST---GPITAKDEVELPRISMDP------KFRDTIVVNAGETF 17146
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
+ V G P P + WL EI+ES + + L +++ D G Y A N
Sbjct: 17147 RLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNV 17206
Query: 632 AG 633
AG
Sbjct: 17207 AG 17208
Score = 35.4 bits (80), Expect = 0.50
Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC---E 493
G V+++ ++ V+K A G L+ + G P P I W + + +Q C
Sbjct: 20371 GGPVIDLPLEYTEVVKYRA---GTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENT 20427
Query: 494 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
+A + I+DA + G Y NA+G S + V + +K
Sbjct: 20428 TDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDK 20468
Score = 35.4 bits (80), Expect = 0.50
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
+ V++G + R + I G+P P W K + A ++ SE + L I ++ D G
Sbjct: 23649 IFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETH--TELVIKEADRGDSG 23706
Query: 230 VYTCLVVNGSGKASMSAELSIQG 252
Y ++ N GK ++ ++ + G
Sbjct: 23707 TYDLVLENKCGKKAVYIKVRVIG 23729
Score = 35.4 bits (80), Expect = 0.50
Identities = 28/92 (30%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDY-DEDGNCSL 1747
P + +R V G RF ++ P EV W+ + ++ES +I Y + G +L
Sbjct: 25877 PRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS--KIHYTNTSGVLTL 25934
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
I D DD Y N GEA+ A L V
Sbjct: 25935 EILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D++V E A+F+C++ P W K Q I F++ D + S++I
Sbjct: 5345 FITPLSDVKVFEKDEAKFECEVSREP-KTFRWLKGTQEITGDDRFELIKDGTKH-SMVIK 5402
Query: 1751 DVCGDDDAKYTCKA 1764
+D+AKY +A
Sbjct: 5403 SAAFEDEAKYMFEA 5416
Score = 35.0 bits (79), Expect = 0.66
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 169 RVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDV 228
R+VV G + R ++G+P P VTW L A + + + V I +
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMV--IKNCQRSHQ 10093
Query: 229 GVYTCLVVNGSGK 241
GVY+ L N +G+
Sbjct: 10094 GVYSLLAKNEAGE 10106
Score = 35.0 bits (79), Expect = 0.66
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 6/82 (7%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNG--QPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
++ G + VRG P P+VTW + G + G L+D LVI +D
Sbjct: 12121 VRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT----MAFLVIPNSTRDDS 12176
Query: 102 GKYTCEATNGSGARQVTVELTV 123
GKY+ N +G + V V + V
Sbjct: 12177 GKYSLTLVNPAGEKAVFVNVRV 12198
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 1/82 (1%)
Query: 1698 LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD 1757
L V G+ D + G P P V W KD ++ + ++ + C+L + V D
Sbjct: 12808 LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRN-LCTLELFSVNRKDS 12866
Query: 1758 AKYTCKAVNSLGEATCTAELIV 1779
YT A NS G + T +L V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888
Score = 35.0 bits (79), Expect = 0.66
Identities = 29/111 (26%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
Query: 546 VAPSKPTAP-IFLQGLSDLKVM--DGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
VA AP + L+GL DL + + S + + + G P P V W + +
Sbjct: 13475 VARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSV 13534
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAG-EVRTQAVLTVQEPHDGTQP 652
E +L + + D G YT N AG + T ++ V +P T P
Sbjct: 13535 ESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGP 13585
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 10/99 (10%)
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
D + AP + P+I K G +V + I G+P P+ +W K +
Sbjct: 13874 DEYEAPTIVLDPTI----KDGLTIKAGDTIVLN------AISILGKPLPKSSWSKAGKDI 13923
Query: 202 QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSG 240
+PS ++ +L I + D G YT N G
Sbjct: 13924 RPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFG 13962
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G ++ + I+G P P V RDG L K T F + T+ LK+
Sbjct: 19988 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPL-KATMRFNTEITAENLTINLKESVTAD 20046
Query: 720 AGQYEILLKNRVGECSCQVSLML 742
AG+YEI N G +++++
Sbjct: 20047 AGRYEITAANSSGTTKAFINIVV 20069
Score = 34.7 bits (78), Expect = 0.86
Identities = 20/79 (25%), Positives = 32/79 (40%), Gaps = 13/79 (16%)
Query: 623 TYTCEAWNSAGE----VRTQAVLTVQEPHDGTQPWFISKP---------RSVTASLGQSV 669
TYT + E VR + + EP T P P S+ G +
Sbjct: 8141 TYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEI 8200
Query: 670 LISCAIAGDPFPTVHWLRD 688
+ +I+G P+PT+ W++D
Sbjct: 8201 ALDASISGSPYPTITWIKD 8219
Score = 34.7 bits (78), Expect = 0.86
Identities = 16/67 (23%), Positives = 28/67 (41%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
G + + G P P + W+ E+ + + SL +++ D+G Y +
Sbjct: 16061 GESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK 16120
Query: 628 AWNSAGE 634
A N AGE
Sbjct: 16121 AKNVAGE 16127
Score = 34.7 bits (78), Expect = 0.86
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ AT + ++G PEP+V W + +T + + +F+ LVI V D G
Sbjct: 18622 LRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQI----EVTSSFTMLVIDNVTRFDSG 18677
Query: 103 KYTCEATNGSGARQVTVELTV 123
+Y N SG++ V + V
Sbjct: 18678 RYNLTLENNSGSKTAFVNVRV 18698
Score = 34.7 bits (78), Expect = 0.86
Identities = 23/93 (24%), Positives = 35/93 (37%), Gaps = 1/93 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
+KP V + D +G P V W KD Q+++E+ + + S
Sbjct: 18896 IKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVT-S 18954
Query: 1747 LIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
L I + +D Y NS G T +IV
Sbjct: 18955 LSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
++D V E F+C++ + WF+++++I +S + I +D +L I D
Sbjct: 6149 LKDTRVKEQQEVVFNCEVNT-EGAKAKWFRNEEAIFDSSKYII-LQKDLVYTLRIRDAHL 6206
Query: 1755 DDDAKYTCKAVNSLGE-ATCTAELIVE 1780
DD A Y N GE A LIVE
Sbjct: 6207 DDQANYNVSLTNHRGENVKSAANLIVE 6233
Score = 34.3 bits (77), Expect = 1.1
Identities = 33/116 (28%), Positives = 48/116 (41%), Gaps = 10/116 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNL-CIKEGATAKFEGRVR--- 57
G+ L S +K +S DPS + PLT AF+ P +L K+G +
Sbjct: 6862 GNKYLYRVSAENKAGVS-DPSEILG-PLTADDAFVEPTMDLSAFKDGLEVIVPNPITILV 6919
Query: 58 ---GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
GYP P TW + + +G R + + LVI D+G YT + N
Sbjct: 6920 PSTGYPRPTATWCFGDKVLETGDRVKMKT-LSAYAELVISPSERSDKGIYTLKLEN 6974
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 2/85 (2%)
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQVLEIHGVNQ 225
G + VK G R + G+P P+V W K L S RV + + + +
Sbjct: 11712 GVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKR 11771
Query: 226 DDVGVYTCLVVNGSGKASMSAELSI 250
D G Y N +G A +++
Sbjct: 11772 SDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 5/79 (6%)
Query: 1692 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1751
S+ + + V G +AR +G P PE+ W +++ + ++ ++ N + + D
Sbjct: 17531 SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTD----KVQIEKGVNYTQLSID 17586
Query: 1752 VCGDDDA-KYTCKAVNSLG 1769
C +DA KY K NS G
Sbjct: 17587 NCDRNDAGKYILKLENSSG 17605
Score = 34.3 bits (77), Expect = 1.1
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 6/109 (5%)
Query: 21 PSRVDSMPLTEAPAFILPPR---NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
P V + E P + L R + +++G + ++G P P W + GQ I+
Sbjct: 23625 PGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDISK-- 23682
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
R ++ T LVI D G Y N G + V +++ V GS
Sbjct: 23683 RAMIATSETHT-ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGS 23730
Score = 33.9 bits (76), Expect = 1.5
Identities = 51/246 (20%), Positives = 95/246 (38%), Gaps = 41/246 (16%)
Query: 451 LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPE 507
L+D E Q+ V + + + + + W + I+ + + + +L + + + +
Sbjct: 2493 LRDLTCTETQNVVFEVELSHSGID-VLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKD 2551
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 567
D G YT A G+ S +TV A SKP L+D V +
Sbjct: 2552 DEGKYTFYA----GENMTSGKLTVAGG------------AISKP--------LTDQTVAE 2587
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCE 627
+ +V+ NP + WL +G + + + E G + L I +D G YT +
Sbjct: 2588 SQEAVFECEVA-NPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYK 2646
Query: 628 AWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWL 686
S +T A L V+ I K +++T + Q + + + V W+
Sbjct: 2647 VATS----KTSAKLKVEAVK-------IKKTLKNLTVTETQDAVFTVELTHPNVKGVQWI 2695
Query: 687 RDGKAL 692
++G L
Sbjct: 2696 KNGVVL 2701
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 3/73 (4%)
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHA 720
+ G + I ++G P PTV W + + L ++ + ++V+K Q H
Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAISSSMVIKNCQRSHQ 10093
Query: 721 GQYEILLKNRVGE 733
G Y +L KN GE
Sbjct: 10094 GVYSLLAKNEAGE 10106
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
G A R + + G P P + W KD + + + +I D + +L+ D D YT
Sbjct: 14979 GEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKI-ADFSTNLVNKDSTRRDSGAYTL 15037
Query: 1763 KAVNSLGEA 1771
A N G A
Sbjct: 15038 TATNPGGFA 15046
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 20/116 (17%)
Query: 20 DPSRVDSMPLTEAPAFILPP---------RNLCIKEGATAKFEGRVRGYPEPQVTWHRNG 70
+P+ V P E +LPP + + I+ T + ++G P P+V W R+
Sbjct: 15344 EPALVPGTPKAEDR--MLPPEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDH 15401
Query: 71 QPITSGGRFLLDCGIRGTFS---LVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
G L I T S L++ V+ D GKY N SG++ V + V
Sbjct: 15402 ------GESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15451
Score = 33.9 bits (76), Expect = 1.5
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+ + G + + V + G P PEV W EI+++ T SL + V D+G
Sbjct: 16455 INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFT--SLVLDNVNRYDSG 16512
Query: 623 TYTCEAWNSAG 633
YT NS+G
Sbjct: 16513 KYTLTLENSSG 16523
Score = 33.9 bits (76), Expect = 1.5
Identities = 19/77 (24%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEI 725
G+ + I + G P P + W++DG+ L K T V + L +K+ G+Y +
Sbjct: 17829 GEDLKIEIPVIGRPRPNISWVKDGEPL-KQTTRVNVEETATSTVLHIKEGNKDDFGKYTV 17887
Query: 726 LLKNRVGECSCQVSLML 742
N G + +S+++
Sbjct: 17888 TATNSAGTATENLSVIV 17904
Score = 33.9 bits (76), Expect = 1.5
Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 17 LSVDPSRVDSMPLT-EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
+++ P V + +T E +P + ++ G E +G P+P ++W ++G P+
Sbjct: 21050 VTIGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKE 21109
Query: 76 GGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
F+ +L I +E GKYT N ++ V +TV
Sbjct: 21110 -SEFVRFSKTENKITLSIKNAKKEHGGKYTVILDN--AVCRIAVPITV 21154
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELHIQDALPEDHGTYTCL 515
G F + + G P P++TW L ++ T L ++D++ D G Y
Sbjct: 22165 GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLT 22224
Query: 516 AENALGQVSCSAWVTV 531
EN G + S V V
Sbjct: 22225 LENTAGVKTFSVTVVV 22240
Score = 33.9 bits (76), Expect = 1.5
Identities = 31/109 (28%), Positives = 48/109 (44%), Gaps = 17/109 (15%)
Query: 1676 FLEAVAEEKPHVKPYFSKTIRDLEVVE----------GSAARFDCKIEGYPDPEVVWFKD 1725
+ E++AE ++P I DLE+ + G++ R + G P P + W K
Sbjct: 22931 YSESIAE----IEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSK- 22985
Query: 1726 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCT 1774
Q I + ID E + LI+ V D KYT +A N G+ + T
Sbjct: 22986 -QGIDLASRAIIDTTESYSL-LIVDKVNRYDAGKYTIEAENQSGKKSAT 23032
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 6/89 (6%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F + D V EG A F C++ + VVWFK+D + SR I E L +
Sbjct: 5079 FMSPLEDQTVKEGETATFVCELS-HEKMHVVWFKNDAKLHTSRTVLIS-SEGKTHKLEMK 5136
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+V DD ++ + + E + TA+L V
Sbjct: 5137 EVTLDDISQIKAQ----VKELSSTAQLKV 5161
Score = 33.5 bits (75), Expect = 1.9
Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 2/84 (2%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F ++D+ E +A F ++ + + V WFK+DQ + +R + DE S+
Sbjct: 5434 FLTPLKDVTAKEKESAVFTVELS-HDNIRVKWFKNDQRLHTTRSVSMQ-DEGKTHSITFK 5491
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCT 1774
D+ DD ++ +A+ EA T
Sbjct: 5492 DLSIDDTSQIRVEAMGMSSEAKLT 5515
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/72 (27%), Positives = 32/72 (44%)
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P+P TW G+ L+ RV + + L I + D G+YT + N S
Sbjct: 6922 TGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISG 6981
Query: 245 SAELSIQGLDSA 256
++++ SA
Sbjct: 6982 EIDVNVIARPSA 6993
Score = 33.5 bits (75), Expect = 1.9
Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 9/116 (7%)
Query: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
S IS+ ++ DP P L ++ + EG R P P V+WH++
Sbjct: 7875 SEISENVVAKDPDC--------KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD 7926
Query: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
G+ + + R + V +V D G YT N G+ ++ + V G
Sbjct: 7927 GKEVKASDRLTMKNDHISAHLEVPKSV-RADAGIYTITLENKLGSATASINVKVIG 7981
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/99 (24%), Positives = 37/99 (37%), Gaps = 5/99 (5%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-----TCEAGVAELHIQDALPEDHGTYT 513
G L+ VRG P P + W + RS A ++ + A D G Y
Sbjct: 11719 GDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYV 11778
Query: 514 CLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
A N G A V V +K ++ ++ V+ + T
Sbjct: 11779 VTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCT 11817
Score = 33.5 bits (75), Expect = 1.9
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 7/87 (8%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVIHA--V 96
+ L ++ G T + V+G P P++TW + + R LD I+ T F + V
Sbjct: 13204 KTLILRAGVTMRLYVPVKGRPPPKITWSKPN--VNLRDRIGLD--IKSTDFDTFLRCENV 13259
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
++ D GKY N G ++ T+ + V
Sbjct: 13260 NKYDAGKYILTLENSCGKKEYTIVVKV 13286
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGK 103
+K G + E V G P P + W ++G+ + + + T +LV D G
Sbjct: 14976 LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFST-NLVNKDSTRRDSGA 15034
Query: 104 YTCEATNGSG 113
YT ATN G
Sbjct: 15035 YTLTATNPGG 15044
Score = 33.5 bits (75), Expect = 1.9
Identities = 33/148 (22%), Positives = 53/148 (35%), Gaps = 5/148 (3%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDR 101
+ +K G K + G P P ++W ++G I R + T L + D
Sbjct: 19302 IVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTL-LTVKDCIRRDT 19360
Query: 102 GKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS----APAVETRPSIWG 157
G+Y N +G R V V V G ++ ++ S P + I
Sbjct: 19361 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDY 19420
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKIT 185
K T + EG++ SCK+T
Sbjct: 19421 YIVEKRETSHLAWTICEGELQMTSCKVT 19448
Score = 33.5 bits (75), Expect = 1.9
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 8/123 (6%)
Query: 4 VKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPP---RNLCIKEGATAKFEGRVRGYP 60
VK V S S S DP E P F + + L +K GA+ RG P
Sbjct: 19660 VKSVNKVGASDPSDSSDPQIAKERE--EEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRP 19717
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P V W + + + R +D T SL I + D GKYT N A +T+
Sbjct: 19718 VPNVLWSKPDTDLRT--RAYVDTTDSRT-SLTIENANRNDSGKYTLTIQNVLSAASLTLV 19774
Query: 121 LTV 123
+ V
Sbjct: 19775 VKV 19777
Score = 33.5 bits (75), Expect = 1.9
Identities = 25/88 (28%), Positives = 35/88 (39%), Gaps = 7/88 (7%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQD 503
S + K V G F + RG PVP + W +P R+ + L I++
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVPNVLW---SKPDTDLRTRAYVDTTDSRTSLTIEN 19749
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTV 531
A D G YT +N L S + V V
Sbjct: 19750 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19777
Score = 33.5 bits (75), Expect = 1.9
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
L V G+ TMTV G P P V+W +++ + + ++ SL I+ D+G
Sbjct: 19699 LIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA--YVDTTDSRTSLTIENANRNDSG 19756
Query: 623 TYTCEAWN 630
YT N
Sbjct: 19757 KYTLTIQN 19764
Score = 33.1 bits (74), Expect = 2.5
Identities = 50/246 (20%), Positives = 84/246 (34%), Gaps = 53/246 (21%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G KL+ + +LSV+ ++ I R+L E FE + +
Sbjct: 2467 GPYKLIVGRVETNCNLSVEKIKI-----------IRGLRDLTCTETQNVVFEVEL-SHSG 2514
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVEL 121
V W+ + I ++ ++ + + L + + ++D GKYT A G + +L
Sbjct: 2515 IDVLWNFKDKEIKPSSKYKIEAHGK-IYKLTVLNMMKDDEGKYTFYA----GENMTSGKL 2569
Query: 122 TVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFS 181
TV G +SK L D+ V E Q F
Sbjct: 2570 TVAGG--------AISKPLTDQ---------------------------TVAESQEAVFE 2594
Query: 182 CKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGK 241
C++ P + WL+ L + + + L I DD+G YT V
Sbjct: 2595 CEVAN-PDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTS 2653
Query: 242 ASMSAE 247
A + E
Sbjct: 2654 AKLKVE 2659
Score = 33.1 bits (74), Expect = 2.5
Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 17/135 (12%)
Query: 1656 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVK--------------PYFSKTIRDLEVV 1701
S T +++E + ++ + L+ +++ K VK PYF+ + D V
Sbjct: 5119 SRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAV 5178
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E C++ D V WFKD + I S + I D L I D +Y
Sbjct: 5179 EKDEITLKCEVS--KDVPVKWFKDGEEIVPSPKYSIKADGLRRI-LKIKKADLKDKGEYV 5235
Query: 1762 CKAVNSLGEATCTAE 1776
C +A T E
Sbjct: 5236 CDCGTDKTKANVTVE 5250
Score = 33.1 bits (74), Expect = 2.5
Identities = 25/92 (27%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1038 VHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-KTTKFIILSQEG-----SLCSVSIEKA 1091
+ V G+ + + V+ P I W+ N + K T + +++E + +SI KA
Sbjct: 8911 IKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKA 8970
Query: 1092 LPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
+ ED+G Y A N G + V V D P+
Sbjct: 8971 VREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9002
Score = 33.1 bits (74), Expect = 2.5
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R+ + G R I+G P P+V W K+D+ +ID G+ L I + +
Sbjct: 10729 REQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKA--RIDVTPVGS-KLEIRNAAHE 10785
Query: 1756 DDAKYTCKAVNSLGEATCTAELIV 1779
D Y+ N G T + +++V
Sbjct: 10786 DGGIYSLTVENPAGSKTVSVKVLV 10809
Score = 33.1 bits (74), Expect = 2.5
Identities = 27/115 (23%), Positives = 48/115 (41%), Gaps = 19/115 (16%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH----IQDALP 506
+D V++ G+ + + G P+P I+W +G I+ R+ E + H ++D +
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIE-ERARTEIISTDNHTLLTVKDCIR 19357
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
D G Y +N G S + V +K P P P+ + GL+
Sbjct: 19358 RDTGQYVLTLKNVAGTRSVAVNCKVLDK-------------PGPPAGPLEINGLT 19399
Score = 33.1 bits (74), Expect = 2.5
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 57 RGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSG 113
+G P P VTW ++ + + S R+ ++ + L I V D GKY NG G
Sbjct: 20799 KGRPPPTVTWRKDEKNLGSDARYSIE-NTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854
Score = 33.1 bits (74), Expect = 2.5
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRG 102
++ GA+ + +G P P W + ++ D +FS L + + D G
Sbjct: 21872 VRAGASIRLFIAYQGRPTPTAVWSKPDSNLS----LRADIHTTDSFSTLTVENCNRNDAG 21927
Query: 103 KYTCEATNGSGARQVTVELTV 123
KYT N SG++ +T + V
Sbjct: 21928 KYTLTVENNSGSKSITFTVKV 21948
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/78 (28%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+ D +V EG + + K+ E VW KD Q ++ S I D+ + L+I D+
Sbjct: 2316 LSDQKVCEGDIVQLEVKVS-LESVEGVWMKDGQEVQPSDRVHIVIDKQSH-MLLIEDMTK 2373
Query: 1755 DDDAKYTCKAVNSLGEAT 1772
+D Y+ + +LG +T
Sbjct: 2374 EDAGNYSF-TIPALGLST 2390
Score = 32.7 bits (73), Expect = 3.3
Identities = 22/88 (25%), Positives = 33/88 (37%), Gaps = 8/88 (9%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFII--------LSQEGSLCSVSIEKALPE 1094
G ++ + + P W +GK K K + L + + I +
Sbjct: 9328 GSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRS 9387
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
G Y AKN AGQ +C+V V D P
Sbjct: 9388 HTGKYSITAKNKAGQKTANCRVKVMDVP 9415
Score = 32.7 bits (73), Expect = 3.3
Identities = 18/68 (26%), Positives = 29/68 (42%), Gaps = 3/68 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG-DDDAKYT 1761
GS D + G P+P+++W K D+ + + Y G + + C D KYT
Sbjct: 22565 GSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQY--TGKRATAVIKFCDRSDSGKYT 22622
Query: 1762 CKAVNSLG 1769
N+ G
Sbjct: 22623 LTVKNASG 22630
Score = 32.3 bits (72), Expect = 4.3
Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 1696 RDLEVVEGSAARFDCKI--EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1753
++LE++EG A F C I E +P V W +DD+++ + + D L++ D
Sbjct: 6062 QNLEILEGEKAEFVCSISKESFP---VQWKRDDKTLESGDKYDVIADGKKRV-LVVKDAT 6117
Query: 1754 GDDDAKYTCKAVNSLGEATCTAELIV 1779
D Y V +G A A L V
Sbjct: 6118 LQDMGTY----VVMVGAARAAAHLTV 6139
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/93 (24%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 545 PVAPSKPTAP--IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
P+ AP + L L + G +T + SG P P+V W + ++ E + H
Sbjct: 10311 PITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHI 10370
Query: 603 EQRGTQHSLCIQEVFPE--DTGTYTCEAWNSAG 633
+ T +L ++++ + D+G Y NS G
Sbjct: 10371 --KTTPATLALEKIKAKRSDSGKYCVVVENSTG 10401
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
I G P P+V W + L DT V + TL++ Q AG+Y I LKN G
Sbjct: 13509 IKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13567
Query: 735 SCQVSL 740
+S+
Sbjct: 13568 EGTISI 13573
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 6/75 (8%)
Query: 452 KDCAVIE-GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALP 506
KD +++ G+ F L+ V G P P + W +G+ ++ + E +A+ L +D+
Sbjct: 14971 KDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELE-GTAKLEIKIADFSTNLVNKDSTR 15029
Query: 507 EDHGTYTCLAENALG 521
D G YT A N G
Sbjct: 15030 RDSGAYTLTATNPGG 15044
Score = 32.3 bits (72), Expect = 4.3
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 25/126 (19%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE---LHIQDALPEDHGTYTCL 515
G + + + G P+P++T +G P++ AE +++++++ D G Y
Sbjct: 19994 GSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEIT 20053
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVM--------- 566
A N+ G + V ++ P PT P+ + +++ V
Sbjct: 20054 AANSSGTTKAFINIVVLDR-------------PGPPTGPVVISDITEESVTLKWEPPKYD 20100
Query: 567 DGSQVT 572
GSQVT
Sbjct: 20101 GGSQVT 20106
Score = 32.3 bits (72), Expect = 4.3
Identities = 22/94 (23%), Positives = 40/94 (42%), Gaps = 2/94 (2%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
P + L+ +K G+ V + +SG P P + W + E+Q + E S
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
+ I++ ++G Y + N+ G A + VQ
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGS--ASATIRVQ 20464
Score = 32.3 bits (72), Expect = 4.3
Identities = 18/87 (20%), Positives = 35/87 (40%), Gaps = 1/87 (1%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
+P + + + G + + G P P +W G + R ++ + L I
Sbjct: 23246 MPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK-VAKLTIRET 23304
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTV 123
D G+YT E N +G T+++ +
Sbjct: 23305 TIRDTGEYTLELKNVTGTTSETIKVII 23331
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/91 (28%), Positives = 44/91 (48%), Gaps = 4/91 (4%)
Query: 1691 FSKTIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
F++ ++D+ E + A F+C+ P +V W+KD + E +++ D + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSE-PFVKVKWYKDGMEVHEGDKYRMHSDRKVH-FLSI 2187
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ D Y+C V T TA+LIVE
Sbjct: 2188 LTIDTSDAEDYSCVLVEDENVKT-TAKLIVE 2217
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 21/119 (17%)
Query: 1625 WQKTGNAVR-------AIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFL 1677
W K G V+ I + S M +I ++ K G+ + + A L + VS +
Sbjct: 2342 WMKDGQEVQPSDRVHIVIDKQSHMLLIEDMT--KEDAGNYSFTIPALGLSTSGRVSVYSV 2399
Query: 1678 EAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+ + ++D+ V+EG+ A +CK+ V W+ +D+ I+ Q
Sbjct: 2400 DVITP------------LKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQ 2446
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 7/80 (8%)
Query: 1694 TIRDLEVVE-GSAARFDCKIEGYPDPEVVWFKD--DQSIRESRHFQIDYDEDGNCSLIIS 1750
++R L +V G R + G P P+V W K D +R+ Q+D D L+I
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG---QVDL-VDTMAFLVIP 12169
Query: 1751 DVCGDDDAKYTCKAVNSLGE 1770
+ DD KY+ VN GE
Sbjct: 12170 NSTRDDSGKYSLTLVNPAGE 12189
Score = 32.0 bits (71), Expect = 5.6
Identities = 24/93 (25%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 659 RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFT-LVLKKVQP 717
R++ G S+ I I G P P V W +D L K+ + E N + FT L++ +
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIE---NTESFTLLIIPECNR 14342
Query: 718 WHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 750
+ G++ + ++N G+ S V++ + ++ L
Sbjct: 14343 YDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14375
Score = 32.0 bits (71), Expect = 5.6
Identities = 20/72 (27%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+D+ VV G + I G P P+VVW KD + + E+ +L++ D
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIR 18276
Query: 1755 DDDAKYTCKAVN 1766
D +Y K N
Sbjct: 18277 TDGGQYILKLSN 18288
Score = 32.0 bits (71), Expect = 5.6
Identities = 38/175 (21%), Positives = 68/175 (38%), Gaps = 15/175 (8%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
K G+ + + G P P+VTW + R + + +L + D G+Y
Sbjct: 22163 KAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT-TKDRTTLTVKDSMRGDSGRY 22221
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
N +G + +V + V G G VS + E+ WGE
Sbjct: 22222 FLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSV--------SAESCVLSWGEPKDGGG 22273
Query: 165 TKLGRVVVKEGQMGRFSCKITG----RPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
T++ +V++ + G + ++ R Q +VT L ++ S RVS + G+
Sbjct: 22274 TEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHL--TKYMEYSFRVSSENRFGV 22326
Score = 31.6 bits (70), Expect = 7.3
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 3/79 (3%)
Query: 1702 EGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYT 1761
E S R I+G P P V W K + + ++ N +LI+ D D KYT
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVE-SSAVNTTLIVYDCQKSDAGKYT 13557
Query: 1762 CKAVNSLG--EATCTAELI 1778
N G E T + +++
Sbjct: 13558 ITLKNVAGTKEGTISIKVV 13576
Score = 31.6 bits (70), Expect = 7.3
Identities = 18/67 (26%), Positives = 29/67 (43%), Gaps = 3/67 (4%)
Query: 458 EGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAE--LHIQDALPEDHGTYTC 514
E +F L+ ++G P P ++W P+ R + E+ L + D D G YT
Sbjct: 13499 ENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13558
Query: 515 LAENALG 521
+N G
Sbjct: 13559 TLKNVAG 13565
Score = 31.6 bits (70), Expect = 7.3
Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT--QHSLCIQEVFPEDTGTYT 625
G + + G P P+V+W +G E++E+ E + T + +L +++ D G Y
Sbjct: 18225 GETFVLEADIRGKPIPDVVWSKDGKELEETA-ARMEIKSTIQKTTLVVKDCIRTDGGQYI 18283
Query: 626 CEAWNSAG 633
+ N G
Sbjct: 18284 LKLSNVGG 18291
Score = 31.2 bits (69), Expect = 9.5
Identities = 30/130 (23%), Positives = 53/130 (40%), Gaps = 17/130 (13%)
Query: 1664 EKLESEEDVSQAFLEAVAEEKPHVK-------------PYFSKTIRDLEVVEGSAARFDC 1710
E L+ E+ ++ E+ EE VK P + D EG
Sbjct: 4205 ESLKPSEEKEESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTT 4264
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD-DAKYTCKAVNSLG 1769
I EV W+ +++ + F+ D++ +L+I V +D +Y C+A+N G
Sbjct: 4265 SITNAK--EVNWYFENKLVPSDEKFKCLQDQN-TYTLVIDKVNTEDHQGEYVCEALNDSG 4321
Query: 1770 EATCTAELIV 1779
+ +A+L V
Sbjct: 4322 KTATSAKLTV 4331
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 8/112 (7%)
Query: 1007 NCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNG 1066
NC+ + T K E A F K Q++ + EG+K C +S + + W +
Sbjct: 6036 NCRLPSSRTDGKVKVHE---LAAEFISKPQNLEILEGEKAEFVCSISKE-SFPVQWKRDD 6091
Query: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
KTL++ + +G + ++ A +D G Y + G A + +TV
Sbjct: 6092 KTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVM----VGAARAAAHLTV 6139
Score = 31.2 bits (69), Expect = 9.5
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 450 VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCE--AGVAELHIQDALP 506
+L V G L +V G P P+ITW + Q R T E + + I D+
Sbjct: 7199 LLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKR 7258
Query: 507 EDHGTYTCLAENALGQVSCSAWVTVHEK 534
D GTY A N G+ + V V +K
Sbjct: 7259 SDTGTYIIEAVNVCGRATAVVEVNVLDK 7286
Score = 31.2 bits (69), Expect = 9.5
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 10/79 (12%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLL-------NGQPIQYARSTCEAGVAE---LHIQDAL 505
V EG + + ++G P P +TW N +P+ Y + V + L I +
Sbjct: 9631 VEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR 9690
Query: 506 PEDHGTYTCLAENALGQVS 524
D G YT A N LG S
Sbjct: 9691 RSDTGLYTITAVNNLGTAS 9709
Score = 31.2 bits (69), Expect = 9.5
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGD 1755
R L V G + R I+G P PEV W KD+ +++ + + + + LII +
Sbjct: 14287 RTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIE---NTESFTLLIIPECNRY 14343
Query: 1756 DDAKYTCKAVNSLGE 1770
D K+ N G+
Sbjct: 14344 DTGKFVMTIENPAGK 14358
Score = 31.2 bits (69), Expect = 9.5
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 14/78 (17%)
Query: 563 LKVMDGSQVTMTVQVSGNPPPEVIW------LHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
L V G + + V + G P PEV W L N I+ +E F L I E
Sbjct: 14289 LVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--------LIIPEC 14340
Query: 617 FPEDTGTYTCEAWNSAGE 634
DTG + N AG+
Sbjct: 14341 NRYDTGKFVMTIENPAGK 14358
Score = 31.2 bits (69), Expect = 9.5
Identities = 16/69 (23%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-ISDVCGDDDAKYT 1761
G + + + G P P V W K DQ +++++ +++++ +++ I++ D Y
Sbjct: 14583 GDNIKVEIPVLGRPKPTVTWKKGDQILKQTQ--RVNFETTATSTILNINECVRSDSGPYP 14640
Query: 1762 CKAVNSLGE 1770
A N +GE
Sbjct: 14641 LTARNIVGE 14649
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
+V G++ + ++G P PT+ W +DGK L + T E+ + LV K
Sbjct: 14973 TVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL-EGTAKLEIKIADFSTNLVNKDSTRRD 15031
Query: 720 AGQYEILLKNRVG 732
+G Y + N G
Sbjct: 15032 SGAYTLTATNPGG 15044
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/75 (29%), Positives = 31/75 (41%), Gaps = 2/75 (2%)
Query: 1696 RDLEVVE-GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
RD+ VV+ G + + I G P P + W KD I E +I D + L + D
Sbjct: 19299 RDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEI-ISTDNHTLLTVKDCIR 19357
Query: 1755 DDDAKYTCKAVNSLG 1769
D +Y N G
Sbjct: 19358 RDTGQYVLTLKNVAG 19372
Score = 31.2 bits (69), Expect = 9.5
Identities = 19/71 (26%), Positives = 30/71 (42%)
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
V V+ G + I+G+P P+VT + VPL+ + R + + + D G
Sbjct: 19989 VYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAG 20048
Query: 230 VYTCLVVNGSG 240
Y N SG
Sbjct: 20049 RYEITAANSSG 20059
Score = 31.2 bits (69), Expect = 9.5
Identities = 20/73 (27%), Positives = 32/73 (43%), Gaps = 5/73 (6%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA-KYT 1761
G++ R +G P P VW K D ++ + D + S + + C +DA KYT
Sbjct: 21875 GASIRLFIAYQGRPTPTAVWSKPDSNL----SLRADIHTTDSFSTLTVENCNRNDAGKYT 21930
Query: 1762 CKAVNSLGEATCT 1774
N+ G + T
Sbjct: 21931 LTVENNSGSKSIT 21943
Score = 31.2 bits (69), Expect = 9.5
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 1/68 (1%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPI-QYARSTCEAGVAELHIQDALPEDHGTYTC 514
V +G L ++G P P W GQ I + A EL I++A D GTY
Sbjct: 23651 VRQGGVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDL 23710
Query: 515 LAENALGQ 522
+ EN G+
Sbjct: 23711 VLENKCGK 23718
>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
Length = 819
Score = 236 bits (601), Expect = 2e-61
Identities = 149/364 (40%), Positives = 195/364 (53%), Gaps = 72/364 (19%)
Query: 1342 GTSEPSQES------ELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF 1394
G EP Q+ V P + V DD P ++R V++ E +S
Sbjct: 454 GNPEPEQDCAARAPVRAEAVRRMPPGAEAGSVVLDDSPAPPAPFEHRVVSVK-ETSISAG 512
Query: 1395 YDI--EERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKL 1452
Y++ E LG G+FGQV R EK T A K K SAK++E+++ EI+IMN L H L
Sbjct: 513 YEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKVKSAKDREDVKNEINIMNQLSHVNL 572
Query: 1453 VQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGI 1512
+Q DAFE K + +V+E V GGELF+RI DE + LTE + + + RQI EGV Y+H+ I
Sbjct: 573 IQLYDAFESKHSCTLVMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYI 632
Query: 1513 VHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYA 1572
+HLDLKPENI+CVN+TG +IK+IDFGLARR + LKV FGTPEF+APEV+NYE + +
Sbjct: 633 LHLDLKPENILCVNQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFP 692
Query: 1573 TDMWSIGVICYIL------------------------------------------NRL-- 1588
TDMWS+GVI Y+L +RL
Sbjct: 693 TDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFEGLSEEAKDFVSRLLV 752
Query: 1589 -------DCTQCLQHPWLMKDTKNMEAK-KLSKDRMK------KYMARRKWQKTGNAVRA 1634
TQCL+H WL N+ AK SK R+K KY+A+RKW+K V A
Sbjct: 753 KEKSCRMSATQCLKHEWL----NNLPAKASRSKTRLKSQLLLQKYIAQRKWKKHFYVVTA 808
Query: 1635 IGRL 1638
RL
Sbjct: 809 ANRL 812
>gi|167466233 myosin light chain kinase family, member 4 [Homo
sapiens]
Length = 388
Score = 221 bits (562), Expect = 6e-57
Identities = 122/287 (42%), Positives = 175/287 (60%), Gaps = 15/287 (5%)
Query: 1379 DYRTVTINTEQKVSDFYDIE--ERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN 1436
D+R VT + V+ FY + E LG G+FGQV + E T A K K K+KE
Sbjct: 89 DHRIVTAK-QGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEE 147
Query: 1437 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1496
++ EIS+MN L H L+Q DAFE K +IV+V+E V GGELF+RIIDE + LTE + I +
Sbjct: 148 VKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILF 207
Query: 1497 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTP 1556
M+QI EG+ ++H+ I+HLDLKPENI+CVN+ +IK+IDFGLARR + LKV FGTP
Sbjct: 208 MKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTP 267
Query: 1557 EFVAPEVINYEPIGYATDMWSIGVICYIL-----------NRLDCTQCLQHPWLMKDTKN 1605
EF+APEV+NY+ + + TDMWS+GVI Y+L + L W ++D +
Sbjct: 268 EFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEF 327
Query: 1606 MEAKKLSKDRMKKYMARRK-WQKTGNAVRAIGRLSSMAMISGLSGRK 1651
+ + +K+ + K + + K W+ + + LS + S L+ +K
Sbjct: 328 QDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQK 374
>gi|14993776 skeletal myosin light chain kinase [Homo sapiens]
Length = 596
Score = 220 bits (560), Expect = 1e-56
Identities = 132/358 (36%), Positives = 186/358 (51%), Gaps = 56/358 (15%)
Query: 1346 PSQESELTTVGEKPEEPKDEVEVSDDDEKEPE-VDYRTVTINTEQKVSDF-YDIEERLGS 1403
PS++SE+ +D ++ DD P +R V + T S+F + +E LG
Sbjct: 234 PSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELRTGNVSSEFSMNSKEALGG 293
Query: 1404 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1463
GKFG V +EK T A K K + K+KE + EI +MN L+H L+Q A E
Sbjct: 294 GKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPH 353
Query: 1464 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1523
IV+ +E + GGELFERI+DED+ LTE + + ++RQI +G+ ++HK ++HLDLKPENI+
Sbjct: 354 EIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENIL 413
Query: 1524 CVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1583
CVN TG +K+IDFGLARR LKV FGTPEF++PEV+NY+ I TDMWS+GVI Y
Sbjct: 414 CVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITY 473
Query: 1584 IL---------------------------------------------------NRLDCTQ 1592
+L R++ Q
Sbjct: 474 MLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQ 533
Query: 1593 CLQHPW---LMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGL 1647
CL HPW L + K + S+ +KKY+ +R+W+K AV A R ++ L
Sbjct: 534 CLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGAL 591
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 200 bits (509), Expect = 9e-51
Identities = 122/364 (33%), Positives = 188/364 (51%), Gaps = 72/364 (19%)
Query: 1383 VTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE------KEN 1436
+T+ ++ V D+YD E LGSG+F V + EK T +A KF K K +E+
Sbjct: 1 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED 60
Query: 1437 IRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKY 1496
I +E+SI+ + HP ++ + +E K +++++LE+V+GGELF+ + +++ LTE E ++
Sbjct: 61 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKE-SLTEEEATEF 119
Query: 1497 MRQISEGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFG 1554
++QI GV Y+H I H DLKPENIM +++ RIK+IDFGLA +++ K +FG
Sbjct: 120 LKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFG 179
Query: 1555 TPEFVAPEVINYEPIGYATDMWSIGVICYIL----------------------------- 1585
TPEFVAPE++NYEP+G DMWSIGVI YIL
Sbjct: 180 TPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDE 239
Query: 1586 ----------------------NRLDCTQCLQHPWLM-KDTKNMEAKKLS---KDRMKKY 1619
R+ LQHPW+ KDT+ ++K S ++ KK+
Sbjct: 240 YFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKF 299
Query: 1620 MARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEA 1679
AR+KW+++ + RLS S LS S L+ E + V +A + A
Sbjct: 300 AARKKWKQSVRLISLCQRLSR----SFLSRSNMSVARSDDTLD----EEDSFVMKAIIHA 351
Query: 1680 VAEE 1683
+ ++
Sbjct: 352 INDD 355
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 193 bits (491), Expect = 1e-48
Identities = 213/855 (24%), Positives = 320/855 (37%), Gaps = 149/855 (17%)
Query: 21 PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFL 80
P ++ AP FI R+ + EG+ E RV G P P+V W G+ + +
Sbjct: 259 PQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQ 318
Query: 81 LDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS-----------FAK 129
+ C +L+I E+D G+YTC ATN SG+ + E+ +EG+ F
Sbjct: 319 IHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKS 378
Query: 130 QLGQ--------PVVSKTLGDRFSAPAVET---------------------RP--SIWGE 158
+ G VS T+G V T RP +
Sbjct: 379 RAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAY 438
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ--PSARV------SVS 210
PP F +L V EGQ+ C++ G P QV W + +Q P R+ S +
Sbjct: 439 FPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTA 498
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF---------- 260
E + L I +D G++TC N G A+ +A+L + ++ N S+
Sbjct: 499 EPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDH 558
Query: 261 ---------VRETKATNSDVRK--EVTNVISKESKLD------SLEAAAKSKNCSSPQRG 303
+ ET + +K E+ V + E L AA + N P RG
Sbjct: 559 FQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRG 618
Query: 304 --GSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA---ARVQPEPRA 358
G ANS P + L S P P+L K +A AR+ +
Sbjct: 619 VNGLINGKANSNKSLPTPAVLLSPTKEP-----PPLLAKPKLGFPKKASRTARIASDEEI 673
Query: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFES 418
G ERK + QP L ++ + A R + + + E
Sbjct: 674 QGTKDAVIQDLERKLRF--KEDLLNNGQPRLTYEE---RMARRLLGADSATVFNIQEPEE 728
Query: 419 KPQSQEVKENQT-------VKFRCEGLAVME---------------VAPSFSSVLKDCAV 456
+ +QE K + +++R E V E +AP F LK +
Sbjct: 729 ETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKI 788
Query: 457 IEGQDFVLQCSVRGTPVPRITWLLNGQPIQ-----YARSTCEAGVAELHIQDALPEDHGT 511
EG C V G P P+I W +G+ I Y G LH + +D G
Sbjct: 789 FEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGN 848
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS------KPTA------------ 553
YT +A N G++SC+ + V +S P +PS +P +
Sbjct: 849 YTIMAANPQGRISCTGRLMVQAVNQRGRS----PRSPSGHPHVRRPRSRSRDSGDENEPI 904
Query: 554 ------PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRG 606
P FLQ DL V +G M +VSG P P++ W +G ++ +S +
Sbjct: 905 QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVREN 964
Query: 607 TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG 666
HSL I+ V D G YTC A N AG+ L V P FI K ++ + G
Sbjct: 965 GVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADG 1024
Query: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-NEDVFTLVLKKVQPWHAGQYEI 725
V + C + G P P + W ++ ++L T + Q N L+++ AG Y +
Sbjct: 1025 YPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTV 1084
Query: 726 LLKNRVGECSCQVSL 740
KN G SC L
Sbjct: 1085 SAKNEAGIVSCTARL 1099
Score = 118 bits (295), Expect = 6e-26
Identities = 179/778 (23%), Positives = 282/778 (36%), Gaps = 108/778 (13%)
Query: 551 PTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE-QRGTQH 609
P AP F+Q L +V +GS+V + +V+GNP P V W G E+ + D + G H
Sbjct: 268 PAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLH 327
Query: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ--------------EPHDGTQPWFI 655
+L I E F +DTG YTC A N +G T A + ++ + G P
Sbjct: 328 TLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQ 387
Query: 656 SKPRSVTASLGQSV----LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
K SV+ ++G S + + I P LC+ G VFT
Sbjct: 388 KKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGT-TTAYFPPVFTKE 446
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP-------RGREPASCEDLC- 763
L+ GQ +L G QV Q S + P + R A E++C
Sbjct: 447 LQNTAVAE-GQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICT 505
Query: 764 ---------GGGVGADGGGSDRYGSLRPG-----WPARGQGWLEEEDGEDVRGVLKRRVE 809
G+ +D YGS A + E GE
Sbjct: 506 LVIAETFPEDAGIFTCSARND-YGSATSTAQLVVTSANTENCSYESMGES---------- 554
Query: 810 TRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDF-RANLQRQVKPKT 868
H + + + +L KK S +++++ ++ RA LQ Q
Sbjct: 555 NNDHFQHFPPPPPILETSSLELASKKPS-------EIQQVNNPELGLSRAALQMQFN--A 605
Query: 869 VSEEERKVHSPQQVDFRSVLAKKGTSK---TPV----PEKVPPPKPATPDFRSVLGGKKK 921
E VH + V+ + K ++K TP P K PPP A P LG KK
Sbjct: 606 AERETNGVHPSRGVN-GLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPK----LGFPKK 660
Query: 922 LPAENGSSSAET-----------LNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMG 970
+S E L K L+N QP + + A L
Sbjct: 661 ASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQP----RLTYEERMARRLLGAD 716
Query: 971 NAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEKR----SESQG 1026
+A +P E S+ ++ L ++ + +R + +E + G
Sbjct: 717 SATVFNIQEPEEETANQEYKVSSCEQRLISEI--EYRLERSPVDESGDEVQYGDVPVENG 774
Query: 1027 TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL--KTTKFIILSQEGSLC 1084
AP F+ KL+ + EG + C+V+ +P I W +GK + K+ + I C
Sbjct: 775 MAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTC 834
Query: 1085 SVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPV 1144
S+ + +D G Y +A N G+ C+ ++ V ++ ++P S P P
Sbjct: 835 SLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQ--AVNQRGRSPRSPSGHPHVRRP-- 890
Query: 1145 LGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMK 1204
D+ + +P + P +Q P D V+ G+ + KV+G +W
Sbjct: 891 RSRSRDSGDENEPI----QERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQL 946
Query: 1205 FRKQIQESEHMKVENSENG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
K ++ K+ ENG L I G YT + N+ G + L V K
Sbjct: 947 DGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAK 1004
Score = 104 bits (260), Expect = 7e-22
Identities = 120/462 (25%), Positives = 178/462 (38%), Gaps = 111/462 (24%)
Query: 262 RETKATNSDVRKE---VTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 318
++TK+ +S V K ++ ++++ S + SL A K RG P + N +P+ P
Sbjct: 108 KQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEK--------RGAKTP-STNVKPKTPH 158
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSIT-LQAARVQPEPRAPGLGVLSPSGEERKRPAPP 377
+ K PQ+ + K ++ I L + +PR SP+GE +P
Sbjct: 159 QRK---------GGPQSQLCDKAANLIEELTSIFKAAKPRNR-----SPNGESS---SPD 201
Query: 378 RPATFPTRQPGLGSQDVVSKAANRRIPMEGQ----RDSAFPKFESKPQSQE---VKENQT 430
P QP + A+ + PME Q R+ P Q + V N+
Sbjct: 202 SGYLSPKNQPS-----ALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRK 256
Query: 431 VKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA-- 488
+ AP F L+ V EG L+C V G P PR+ W G+ +
Sbjct: 257 SHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPD 316
Query: 489 -RSTCEAG-VAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS-RKSEYL-- 543
+ CE G + L I +A +D G YTCLA N G + SA V + S+ SE L
Sbjct: 317 IQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAF 376
Query: 544 ------LPVAPSKPTA-------------------------------------------- 553
+P A K T+
Sbjct: 377 KSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTT 436
Query: 554 ----PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
P+F + L + V +G V + +V G PP +V W G+EIQ+S DF Q+ +
Sbjct: 437 AYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRS 496
Query: 610 --------SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
+L I E FPED G +TC A N G + A L V
Sbjct: 497 TAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 99.0 bits (245), Expect = 4e-20
Identities = 66/220 (30%), Positives = 95/220 (43%), Gaps = 31/220 (14%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLV 92
P F+ P +L ++EG + + +V G P P ++W +G+P+ + G SL+
Sbjct: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
Query: 93 IHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETR 152
I V D G YTC ATN +G ++EL V A +
Sbjct: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHK---------------------- 1008
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA-RVSVSE 211
PP F KL V +G R C++ G P PQ+ W K N L S RVS+ +
Sbjct: 1009 -------PPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQ 1061
Query: 212 KN-GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
N G L I G ++D G YT N +G S +A L +
Sbjct: 1062 DNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 93.6 bits (231), Expect = 2e-18
Identities = 66/206 (32%), Positives = 91/206 (44%), Gaps = 22/206 (10%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAELH 500
P F D V EG+ + C V G P P ++W L+G+P++ + E GV L
Sbjct: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
I+ D G YTC+A N GQ S S + V K++ + P+F++ L
Sbjct: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKP--------------PVFIEKL 1016
Query: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED---FHFEQRGTQHSLCIQEVF 617
+ V DG V + +V G PPP++ W + S D H + G L IQ
Sbjct: 1017 QNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHG-YICLLIQGAT 1075
Query: 618 PEDTGTYTCEAWNSAGEVRTQAVLTV 643
ED G YT A N AG V A L V
Sbjct: 1076 KEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 85.5 bits (210), Expect = 4e-16
Identities = 100/418 (23%), Positives = 177/418 (42%), Gaps = 67/418 (16%)
Query: 889 AKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNA 948
A+K +KTP KP TP R GG + + ++ E L + +++KP N
Sbjct: 140 AEKRGAKTPSTNV----KPKTPHQRK--GGPQSQLCDKAANLIEELTS-IFKAAKP-RNR 191
Query: 949 QPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDV-- 1006
P+G ++ + L P +P+ L + P E+ + E++++VK+
Sbjct: 192 SPNGE----SSSPDSGYLSPKN--QPSALLSASASQSPMED-----QGEMEREVKSPGAR 240
Query: 1007 NCKRGHAG-TTDNEKRSESQG-------TAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPA 1058
+C + + + ++S Q AP F QKL+ VAEG ++ L+C+V+ +P
Sbjct: 241 HCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTP 300
Query: 1059 TIIWTLNGKTLKTTKFI-ILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVT 1117
+ W GK L T I I + G L ++ I +A +D G Y C+A N +G S +V
Sbjct: 301 RVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVF 360
Query: 1118 VDDAPASE-NTKAPEMKSR--------RPKSSLPPVLGTESDAT-------------VKK 1155
++ A +++ ++++ KSR + +S+ +G+ S T V++
Sbjct: 361 IEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQ 420
Query: 1156 KPAPKT-------PPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQ 1208
+P + A PP + ++ V G+ V L +V G P+ W + +
Sbjct: 421 VHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSE 480
Query: 1209 IQESEHMKV--------ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
IQ+S ++ E L I E G +T N GS + L V
Sbjct: 481 IQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 77.0 bits (188), Expect = 2e-13
Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR-ESRHFQIDYDEDGNCSL 1747
P+F ++ ++ EG F C++ G P P++ WFKD + I +S H+ I D DG CSL
Sbjct: 777 PFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSL 836
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
+ DDD YT A N G +CT L+V+ + +
Sbjct: 837 HTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQ 873
Score = 70.1 bits (170), Expect = 2e-11
Identities = 47/150 (31%), Positives = 70/150 (46%), Gaps = 4/150 (2%)
Query: 1636 GRLSSMA--MISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSK 1693
GR+S M+ ++ R S SP+ + + S S E + E +P+F +
Sbjct: 858 GRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQER--FFRPHFLQ 915
Query: 1694 TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVC 1753
DL V EG R DCK+ G P P++ W D + +R ++ E+G SLII V
Sbjct: 916 APGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVT 975
Query: 1754 GDDDAKYTCKAVNSLGEATCTAELIVETME 1783
D YTC A N G+ + + EL+V E
Sbjct: 976 SRDAGIYTCIATNRAGQNSFSLELVVAAKE 1005
Score = 67.8 bits (164), Expect = 9e-11
Identities = 33/102 (32%), Positives = 52/102 (50%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + +R EV EGS +C++ G P P V WF + + + + QI + +LI
Sbjct: 271 PRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLI 330
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1790
I++ DD +YTC A N G T +AE+ +E + + E
Sbjct: 331 IAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSE 372
Score = 63.9 bits (154), Expect = 1e-09
Identities = 31/98 (31%), Positives = 53/98 (54%), Gaps = 7/98 (7%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 1741
P F+K +++ V EG +C++ G P +V WF+ I++S F+I +
Sbjct: 441 PVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEP 500
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ C+L+I++ +D +TC A N G AT TA+L+V
Sbjct: 501 EEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVV 538
Score = 63.5 bits (153), Expect = 2e-09
Identities = 57/233 (24%), Positives = 88/233 (37%), Gaps = 45/233 (19%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1087
P F Q D+ V EGK + C+VS P + W L+GK ++ + +L +E + S+
Sbjct: 911 PHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLI 970
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
IE D G+Y C+A N AGQ S ++ V
Sbjct: 971 IEPVTSRDAGIYTCIATNRAGQNSFSLELVV----------------------------- 1001
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
+A PP I+ ++ V G V L +V G P W K +
Sbjct: 1002 -------------AAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENE 1048
Query: 1208 QIQESEHMKVENSENGSKLTIL--AARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ S + +N + +L A +E G YT+ +N+ G L V
Sbjct: 1049 SLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 60.8 bits (146), Expect = 1e-08
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 1680 VAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HFQID 1738
VA ++ H P F + +++ V +G R +C++ G P P++ W K+++S+ S +
Sbjct: 1001 VAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMH 1060
Query: 1739 YDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
D G L+I +D YT A N G +CTA L V
Sbjct: 1061 QDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDV 1101
Score = 49.3 bits (116), Expect = 3e-05
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEA-----GVAEL 499
P F L++ V +G L+C V G P P+I W + + ++ G L
Sbjct: 1010 PVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICL 1069
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
IQ A ED G YT A+N G VSC+A + V+
Sbjct: 1070 LIQGATKEDAGWYTVSAKNEAGIVSCTARLDVY 1102
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 2/102 (1%)
Query: 647 HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEV-LQNE 705
H P FI K RS + G V + C + G+P P V W +GK L +T ++ +
Sbjct: 266 HFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKEL-HNTPDIQIHCEGG 324
Query: 706 DVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
D+ TL++ + G+Y L N G + + ++ +S+
Sbjct: 325 DLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASS 366
>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
Length = 454
Score = 191 bits (485), Expect = 5e-48
Identities = 95/206 (46%), Positives = 138/206 (66%), Gaps = 9/206 (4%)
Query: 1388 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFK------AYSAKEKENIRQEI 1441
++ V D Y++ E LGSG+F V + +K T K +A KF K + +E I +E+
Sbjct: 6 QEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREV 65
Query: 1442 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1501
+I+ + HP ++ D FE K ++V++LE+VSGGELF+ + +++ LTE E ++++QI
Sbjct: 66 NILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKE-SLTEDEATQFLKQIL 124
Query: 1502 EGVEYIHKQGIVHLDLKPENIMCVNKT--GTRIKLIDFGLARRLENAGSLKVLFGTPEFV 1559
+GV Y+H + I H DLKPENIM ++K RIKLIDFG+A ++E K +FGTPEFV
Sbjct: 125 DGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFV 184
Query: 1560 APEVINYEPIGYATDMWSIGVICYIL 1585
APE++NYEP+G DMWSIGVI YIL
Sbjct: 185 APEIVNYEPLGLEADMWSIGVITYIL 210
>gi|14670383 death-associated kinase 2 [Homo sapiens]
Length = 370
Score = 189 bits (479), Expect = 3e-47
Identities = 97/206 (47%), Positives = 136/206 (66%), Gaps = 9/206 (4%)
Query: 1388 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAK------EKENIRQEI 1441
+QKV DFYDI E LGSG+F V + EK T +A KF K ++ +E I +E+
Sbjct: 16 QQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSRASRRGVSREEIEREV 75
Query: 1442 SIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQIS 1501
SI+ + H ++ D +E + ++V++LE+VSGGELF+ + ++ L+E E +++QI
Sbjct: 76 SILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKE-SLSEEEATSFIKQIL 134
Query: 1502 EGVEYIHKQGIVHLDLKPENIMCVNKTGT--RIKLIDFGLARRLENAGSLKVLFGTPEFV 1559
+GV Y+H + I H DLKPENIM ++K IKLIDFGLA +E+ K +FGTPEFV
Sbjct: 135 DGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFV 194
Query: 1560 APEVINYEPIGYATDMWSIGVICYIL 1585
APE++NYEP+G DMWSIGVI YIL
Sbjct: 195 APEIVNYEPLGLEADMWSIGVITYIL 220
>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
Length = 2986
Score = 185 bits (469), Expect = 4e-46
Identities = 156/588 (26%), Positives = 244/588 (41%), Gaps = 98/588 (16%)
Query: 1125 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1176
ENT E R+PK L + + + ++ P +M P IQ PE
Sbjct: 2415 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 2474
Query: 1177 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1227
D G++V L KV G T TW + I ++++ V + ++G L
Sbjct: 2475 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 2534
Query: 1228 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1287
I + G YT + N G+ + V P P P A + +S+ L W S
Sbjct: 2535 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 2593
Query: 1288 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
G + Y++E + ++ W++ +A+ T ++DL P Y+FRV A N +G S P
Sbjct: 2594 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 2653
Query: 1347 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1404
S+ SE + PE D TI+ ++ Y +G G
Sbjct: 2654 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 2693
Query: 1405 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1464
+F V + + K TRK A KF K+KE E +++ L HP+ + D +E +
Sbjct: 2694 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 2752
Query: 1465 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1524
+++LE++ G L + +++ D EL E + Y+R I E ++Y+H + HLD+KPEN++
Sbjct: 2753 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 2811
Query: 1525 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1583
+ R+KLID A ++ + L G PEF APEVI P+ TD+WSIGV+ Y
Sbjct: 2812 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 2871
Query: 1584 IL---------------------------------------------------NRLDCTQ 1592
++ R
Sbjct: 2872 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 2931
Query: 1593 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1640
CLQHPWL + L R+ ++ RRK Q N VR I + S
Sbjct: 2932 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 2976
Score = 71.2 bits (173), Expect = 8e-12
Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 491
+ EVAP F L D + G +LQC V G P P ITW Q I Y S+
Sbjct: 2466 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 2525
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 551
C++G L I + +P+D G YTC+A N G S SA V V +P AP++P
Sbjct: 2526 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 2575
Query: 552 TA 553
A
Sbjct: 2576 IA 2577
Score = 60.1 bits (144), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208
P+ E P+F L V G CK+ GRP+P +TW + + SA +
Sbjct: 2463 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 2522
Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266
VS +G L+I + D G+YTC+ N G S SA + +QG+ +A NR +E
Sbjct: 2523 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 2582
Query: 267 TNSDVR 272
T+ +R
Sbjct: 2583 TSVILR 2588
Score = 58.9 bits (141), Expect = 4e-08
Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%)
Query: 929 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 987
S E + AV QP+ P P L P+ A AE+ G+ K
Sbjct: 2343 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 2400
Query: 988 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1024
L+ + E++ KN D+ + T++ + SE
Sbjct: 2401 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 2460
Query: 1025 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1073
Q AP F L DV G ++LQC+V P TI W + + T
Sbjct: 2461 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 2520
Query: 1074 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1133
+ + S + ++ I +P+D G+Y C+A ND G S V V PA+ N + +
Sbjct: 2521 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 2580
Query: 1134 S 1134
S
Sbjct: 2581 S 2581
Score = 50.1 bits (118), Expect = 2e-05
Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 529 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
V+V E SS +SE +L + AP FL L D+ + G V + +V
Sbjct: 2436 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 2495
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 633
G P P + W I ++++ + + +L I + P+D+G YTC A N G
Sbjct: 2496 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 2555
Query: 634 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 688
T A + VQ P +P I++ RS T+ L S +C I+G TV + +
Sbjct: 2556 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 2610
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
G + + + V D + LV++ + P Q+ + N G
Sbjct: 2611 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 2649
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87
AP F++P ++ G T + +V G P+P +TW Q I S + + G
Sbjct: 2470 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 2529
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
+L I + +D G YTC ATN G + + V+G
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 2567
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1742
V P F + D+ + G CK+ G P P + W DQ+I ++ + Y +
Sbjct: 2469 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 2528
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
G +L I ++ D YTC A N G + +A + V+
Sbjct: 2529 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 2566
Score = 35.0 bits (79), Expect = 0.66
Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 706
P F+ VT LG +V++ C + G P PT+ W + + DT + +
Sbjct: 2471 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 2529
Query: 707 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
TL + + P +G Y + N G S ++ +Q A
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 2570
>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
Length = 1289
Score = 185 bits (469), Expect = 4e-46
Identities = 156/588 (26%), Positives = 244/588 (41%), Gaps = 98/588 (16%)
Query: 1125 ENTKAPEMKS-RRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMP---PQIIQ--FPE-- 1176
ENT E R+PK L + + + ++ P +M P IQ PE
Sbjct: 718 ENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFL 777
Query: 1177 ----DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK----VENSENGS-KLT 1227
D G++V L KV G T TW + I ++++ V + ++G L
Sbjct: 778 VPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLK 837
Query: 1228 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSS 1287
I + G YT + N G+ + V P P P A + +S+ L W S
Sbjct: 838 ICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAP-NRPIAQERSCTSVILRWLPPS 896
Query: 1288 YDGGSAVQSYSIEIWDSANKTWKE-LATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEP 1346
G + Y++E + ++ W++ +A+ T ++DL P Y+FRV A N +G S P
Sbjct: 897 STGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLP 956
Query: 1347 SQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT--VTINTEQKVSDFYDIEERLGSG 1404
S+ SE + PE D TI+ ++ Y +G G
Sbjct: 957 SEPSEFVRL--------------------PEYDAAADGATISWKENFDSAYTELNEIGRG 996
Query: 1405 KFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKAN 1464
+F V + + K TRK A KF K+KE E +++ L HP+ + D +E +
Sbjct: 997 RFSIVKKCIHKATRKDVAVKFVSK-KMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTS 1055
Query: 1465 IVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMC 1524
+++LE++ G L + +++ D EL E + Y+R I E ++Y+H + HLD+KPEN++
Sbjct: 1056 YILILELMDDGRLLDYLMNHD-ELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLI 1114
Query: 1525 VNKTGT-RIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICY 1583
+ R+KLID A ++ + L G PEF APEVI P+ TD+WSIGV+ Y
Sbjct: 1115 DLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTY 1174
Query: 1584 IL---------------------------------------------------NRLDCTQ 1592
++ R
Sbjct: 1175 VMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAAT 1234
Query: 1593 CLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSS 1640
CLQHPWL + L R+ ++ RRK Q N VR I + S
Sbjct: 1235 CLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQ---NDVRPIPNVKS 1279
Score = 71.2 bits (173), Expect = 8e-12
Identities = 45/122 (36%), Positives = 58/122 (47%), Gaps = 18/122 (14%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--------QYARST 491
+ EVAP F L D + G +LQC V G P P ITW Q I Y S+
Sbjct: 769 IQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSS 828
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 551
C++G L I + +P+D G YTC+A N G S SA V V +P AP++P
Sbjct: 829 CDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG----------VPAAPNRP 878
Query: 552 TA 553
A
Sbjct: 879 IA 880
Score = 60.1 bits (144), Expect = 2e-08
Identities = 40/126 (31%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL----QPSARVS 208
P+ E P+F L V G CK+ GRP+P +TW + + SA +
Sbjct: 766 PNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYT 825
Query: 209 VSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-NRSFVRETKA 266
VS +G L+I + D G+YTC+ N G S SA + +QG+ +A NR +E
Sbjct: 826 VSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSC 885
Query: 267 TNSDVR 272
T+ +R
Sbjct: 886 TSVILR 891
Score = 58.9 bits (141), Expect = 4e-08
Identities = 58/241 (24%), Positives = 89/241 (36%), Gaps = 37/241 (15%)
Query: 929 SSAETLNAKAVESSKPLSNAQPSGPLKPVGNA-KPAETLKPMGNAKPAETLKPMGNAKPD 987
S E + AV QP+ P P L P+ A AE+ G+ K
Sbjct: 646 SQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAAESSD--GSIKKS 703
Query: 988 ---ENLKSASKEELKKDVKN---------DVNCKRGHAGTTDNEKRSES----------- 1024
L+ + E++ KN D+ + T++ + SE
Sbjct: 704 CSWHTLRMRKRAEVENTGKNEATGPRKPKDILGNKVSVKETNSSEESECDDLDPNTSMEI 763
Query: 1025 ------QGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTK----- 1073
Q AP F L DV G ++LQC+V P TI W + + T
Sbjct: 764 LNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSAT 823
Query: 1074 FIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMK 1133
+ + S + ++ I +P+D G+Y C+A ND G S V V PA+ N + +
Sbjct: 824 YTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQER 883
Query: 1134 S 1134
S
Sbjct: 884 S 884
Score = 50.1 bits (118), Expect = 2e-05
Identities = 59/224 (26%), Positives = 96/224 (42%), Gaps = 30/224 (13%)
Query: 529 VTVHEKKSSRKSEY----------LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
V+V E SS +SE +L + AP FL L D+ + G V + +V
Sbjct: 739 VSVKETNSSEESECDDLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVC 798
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGT-----QHSLCIQEVFPEDTGTYTCEAWNSAG 633
G P P + W I ++++ + + +L I + P+D+G YTC A N G
Sbjct: 799 GRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHG 858
Query: 634 EVRTQAVLTVQ-EPHDGTQPWFISKPRSVTAS----LGQSVLISCAIAGDPFPTVHWLRD 688
T A + VQ P +P I++ RS T+ L S +C I+G TV + +
Sbjct: 859 TTSTSATVKVQGVPAAPNRP--IAQERSCTSVILRWLPPSSTGNCTISG---YTVEYREE 913
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
G + + + V D + LV++ + P Q+ + N G
Sbjct: 914 GSQIWQQS----VASTLDTY-LVIEDLSPGCPYQFRVSASNPWG 952
Score = 45.8 bits (107), Expect = 4e-04
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI----TSGGRFLLDCGIRG 87
AP F++P ++ G T + +V G P+P +TW Q I S + + G
Sbjct: 773 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 832
Query: 88 TFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG 125
+L I + +D G YTC ATN G + + V+G
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQG 870
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD----ED 1742
V P F + D+ + G CK+ G P P + W DQ+I ++ + Y +
Sbjct: 772 VAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDS 831
Query: 1743 GNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
G +L I ++ D YTC A N G + +A + V+
Sbjct: 832 GEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 869
Score = 35.0 bits (79), Expect = 0.66
Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ-----NED 706
P F+ VT LG +V++ C + G P PT+ W + + DT + +
Sbjct: 774 PEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNIL-DTDNSSATYTVSSCDSG 832
Query: 707 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
TL + + P +G Y + N G S ++ +Q A
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPA 873
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 166 bits (421), Expect = 1e-40
Identities = 152/617 (24%), Positives = 245/617 (39%), Gaps = 100/617 (16%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P F L VVV G C IT P PQV+W K L+ R+ + + L +
Sbjct: 722 PVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLL 781
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
D G Y N G+A+ +A L+++ + S +T S
Sbjct: 782 REARAADAGSYMATATNELGQATCAASLTVR------------PGGSTSPFSSPIT---S 826
Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340
E L E P+ G + P +P P + + D+ AP T +
Sbjct: 827 DEEYLSPPE--------EFPEPGETWPRTPTMKPSPSQNRR---SSDTGSKAPPTFKVSL 875
Query: 341 TSSSI-----TLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVV 395
S+ + + RVQ EP+ P + L ++P P F +++
Sbjct: 876 MDQSVREGQDVIMSIRVQGEPK-PVVSWL-----RNRQPVRPDQRRF--------AEEAE 921
Query: 396 SKAANRRIPMEGQRDSAFP--KFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKD 453
RI + D+ F K ++ +++ + V+ E ++ +AP L+D
Sbjct: 922 GGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAP-----LQD 976
Query: 454 CAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTC----EAGVAELHIQDALPEDH 509
V G+ + +C V G + WL G+ +Q A C + +L + +D
Sbjct: 977 VDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDS 1036
Query: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
G YTC A +++CSA +TV PS AP+F + L D++V++G
Sbjct: 1037 GVYTCKLSTAKDELTCSARLTVR---------------PS--LAPLFTRLLEDVEVLEGR 1079
Query: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
++SG PPP V W H G ++ESE+ Q G HSL I V ED G Y A
Sbjct: 1080 AARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAV 1139
Query: 630 NSAGEVRTQAVLTVQEPHDGTQ--------------------------PWFISKPRSVTA 663
N+ G+ A L V+EP P F+ + +
Sbjct: 1140 NTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEV 1199
Query: 664 SLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
L + ++ C + G P+PT+ W +G + + + + Q DV LV V P HAG Y
Sbjct: 1200 GLAKEAMLECQVTGLPYPTISWFHNGHRI-QSSDDRRMTQYRDVHRLVFPAVGPQHAGVY 1258
Query: 724 EILLKNRVGECSCQVSL 740
+ ++ N++G+ +C L
Sbjct: 1259 KSVIANKLGKAACYAHL 1275
Score = 144 bits (364), Expect = 6e-34
Identities = 98/356 (27%), Positives = 168/356 (47%), Gaps = 58/356 (16%)
Query: 1389 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1448
+++SDFYDI + +G G F + R+VE+ + +A KF + AK K + R+E ++ L
Sbjct: 1595 RRLSDFYDIHQEIGRGAFSYLRRIVERSSGLEFAAKFIPS-QAKPKASARREARLLARLQ 1653
Query: 1449 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1508
H ++ +AFE + +V+V E+ + EL ERI + + E E YMRQ+ EG+ Y+H
Sbjct: 1654 HDCVLYFHEAFERRRGLVIVTELCTE-ELLERIARKP-TVCESEIRAYMRQVLEGIHYLH 1711
Query: 1509 KQGIVHLDLKPENIMCVNKTG--TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1566
+ ++HLD+KPEN++ + ++++ DFG A+ L +GTPEFVAPE++N
Sbjct: 1712 QSHVLHLDVKPENLLVWDGAAGEQQVRICDFGNAQELTPGEPQYCQYGTPEFVAPEIVNQ 1771
Query: 1567 EPIGYATDMWSIGVICY------------------------------------------- 1583
P+ TD+W +GV+ +
Sbjct: 1772 SPVSGVTDIWPVGVVAFLCLTGISPFVGENDRTTLMNIRNYNVAFEETTFLSLSREARGF 1831
Query: 1584 -----ILNRLDCT--QCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIG 1636
+ +RL T + L+HPW K E +S D +K +++RR+WQ++ + +
Sbjct: 1832 LIKVLVQDRLRPTAEETLEHPWFKTQAKGAE---VSTDHLKLFLSRRRWQRSQISYKCHL 1888
Query: 1637 RLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFS 1692
L + + + P P + L S D + LE + ++P FS
Sbjct: 1889 VLRPIPELLRAPPERVWVTMPRRPPPSGGLSSSSDSEEEELEELPSVPRPLQPEFS 1944
Score = 117 bits (294), Expect = 8e-26
Identities = 135/529 (25%), Positives = 202/529 (38%), Gaps = 77/529 (14%)
Query: 290 AAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQA 349
AAA+ + SS ++ G P S+ R E + R Q P+ T S +
Sbjct: 551 AAAQPPSPSSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPL---TRSRAIQEC 607
Query: 350 ARVQPEPRA--PGLGVLSPSGEERKRPAPPRPATF-PTRQPGLGSQDV--------VSKA 398
P P A P +P G RKR P + F P PGL V
Sbjct: 608 RSPVPPPAADPPEARTKAPPG--RKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPE 665
Query: 399 ANRRIPMEGQRDSAFPKFE------------SKPQSQEVKENQTVKFRCEGLAVMEVAPS 446
A +R+ + D + ++ ++P S E+ E+ + G +E AP
Sbjct: 666 AEKRLRRGPEEDGPWGPWDRRGARSQGKGRRARPTSPEL-ESSDDSYVSAGEEPLE-APV 723
Query: 447 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---IQD 503
F L++ V G D +L+C + P P+++W +G ++ E H +++
Sbjct: 724 FEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLRE 783
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS--------SRKSEYLLP---------V 546
A D G+Y A N LGQ +C+A +TV S + EYL P
Sbjct: 784 ARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGET 843
Query: 547 APSKPT------------------APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWL 588
P PT P F L D V +G V M+++V G P P V WL
Sbjct: 844 WPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWL 903
Query: 589 HNGNEIQ-ESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647
N ++ + F E G L I D G YTC+A N G + +A L V+
Sbjct: 904 RNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHP 963
Query: 648 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK----ALCKDTGHFEVLQ 703
+ ++ + V G+ L C +AG V WL G+ AL K HF+ +
Sbjct: 964 ESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRK 1023
Query: 704 NEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 752
+ L+L V +G Y L E +C L ++ S A R
Sbjct: 1024 CK----LLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTR 1068
Score = 117 bits (294), Expect = 8e-26
Identities = 162/678 (23%), Positives = 242/678 (35%), Gaps = 120/678 (17%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
V + P + + A + P +++ + G A FE V G + +V W G+ + LL C
Sbjct: 959 VRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA---LLKC 1015
Query: 84 GIR---GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTL 140
+ L++ +VHE+D G YTC+ + + LTV
Sbjct: 1016 KMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV----------------- 1058
Query: 141 GDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVP 200
RPS+ P F L V V EG+ RF CKI+G P P VTW P
Sbjct: 1059 -----------RPSL----APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCP 1103
Query: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSF 260
++ S + + + G+ L I V +D G+Y VN G+A SA+L ++ +A
Sbjct: 1104 MEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGP 1163
Query: 261 VRETKATNSDVRKEVTNVISKES------KLDSLEAAAKSKNCSSPQRGGSP----PWAA 310
+ + S + + + S L LE + Q G P W
Sbjct: 1164 SSKLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFH 1223
Query: 311 NS-QPQPPRESKLESCKD-----SPRTAPQ---------TPVLQKTSSSITLQAARVQPE 355
N + Q + ++ +D P PQ L K + L V P
Sbjct: 1224 NGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPG 1283
Query: 356 PRAPGLGVLSPSG----------EERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP- 404
P V++ +G P T+ + LGS + R P
Sbjct: 1284 PPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLTYTVQHQVLGSDQWTALVTGLREPG 1343
Query: 405 --MEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDF 462
G R F + S VK + E + ++E P+ A+++ D
Sbjct: 1344 WAATGLRKGVQHIF--RVLSTTVKSSSKPSPPSEPVQLLEHGPTLEEA---PAMLDKPDI 1398
Query: 463 VLQCSVRGTPVPRITWLLNGQPIQYARSTC-------EAGVAELHIQD----------AL 505
V V G P +T N Q +C AGV EL D
Sbjct: 1399 VY--VVEGQPA-SVTVTFNHVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVS 1455
Query: 506 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 565
D G TC A N G +CS + + E AP F + D++V
Sbjct: 1456 RRDMGALTCTARNRHGTQTCSVTLELAE-------------------APRFESIMEDVEV 1496
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 625
G V V G P P+++W + + ES F + SL + +D G YT
Sbjct: 1497 GAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLVVLSTGAQDGGVYT 1556
Query: 626 CEAWNSAGEVRTQAVLTV 643
C A N AGEV +A L V
Sbjct: 1557 CTAQNLAGEVSCKAELAV 1574
Score = 117 bits (293), Expect = 1e-25
Identities = 91/331 (27%), Positives = 147/331 (44%), Gaps = 25/331 (7%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
AP F + L+DV V EG+ C++S PP + WT G ++ ++ + L Q+G L S+
Sbjct: 1063 APLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLH 1122
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
I ED GLY A N GQA CS Q+ V++ P + P S L
Sbjct: 1123 IAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEE---------PRTAASGPSSKL------ 1167
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
E ++ ++P + ++ P ++ +D +V + L +VTG T +W
Sbjct: 1168 EKMPSIPEEPEQGELERLSI-PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGH 1226
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVD-KPDPPA 1266
+IQ S+ ++ + +L A +H G Y ++ NKLG +L V D P PP
Sbjct: 1227 RIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPD 1286
Query: 1267 GTPCASDIRSSSLTLSW-----YGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSF 1320
G P + +TL+W + D S +Y+++ + W L T R +
Sbjct: 1287 GAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSL--TYTVQHQVLGSDQWTALVTGLREPGW 1344
Query: 1321 NVQDLLPDHEYKFRVRAINVYGTSEPSQESE 1351
L ++ FRV + V +S+PS SE
Sbjct: 1345 AATGLRKGVQHIFRVLSTTVKSSSKPSPPSE 1375
Score = 112 bits (281), Expect = 2e-24
Identities = 76/245 (31%), Positives = 123/245 (50%), Gaps = 13/245 (5%)
Query: 1346 PSQESELTTVGEKPEEPKDEVEVS--DDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGS 1403
P E T V + P EV S P + T+ QK F + + R
Sbjct: 2918 PEPPPEPTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKAR--- 2974
Query: 1404 GKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHPKLVQCVDAFEEKA 1463
G+FG V E T + + K Y+A+ K + QE ++ LHH +++ +A+
Sbjct: 2975 GRFGVVRACRENATGRTFVAKIVP-YAAEGKRRVLQEYEVLRTLHHERIMSLHEAYITPR 3033
Query: 1464 NIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIM 1523
+V++ E EL + D F +E + YM Q+ +G++Y+H ++HLD+KP+N++
Sbjct: 3034 YLVLIAESCGNRELLCGLSDR-FRYSEDDVATYMVQLLQGLDYLHGHHVLHLDIKPDNLL 3092
Query: 1524 CVNKTGTRIKLIDFGLARRLENAGSLKVL---FGTPEFVAPEVINYEPIGYATDMWSIGV 1580
+K++DFG A+ N +L+ L GT EF+APE++ EPIG ATD+W GV
Sbjct: 3093 LAPDNA--LKIVDFGSAQPY-NPQALRPLGHRTGTLEFMAPEMVKGEPIGSATDIWGAGV 3149
Query: 1581 ICYIL 1585
+ YI+
Sbjct: 3150 LTYIM 3154
Score = 111 bits (277), Expect = 7e-24
Identities = 110/463 (23%), Positives = 180/463 (38%), Gaps = 52/463 (11%)
Query: 847 KEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPK 906
+E+ RA LQR P+ E R+V +P + P +
Sbjct: 508 EELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDE 567
Query: 907 PATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETL 966
P P R G + P E + + S+ + + P P + A T
Sbjct: 568 PGRPRSRGPAGRTE--PGEGPQQEVRRRDQFPLTRSRAIQECRSPVP-PPAADPPEARTK 624
Query: 967 KPMGNAK--PAETLKPM--------GNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTT 1016
P G + PA+ ++ + G A P K+ + E +K ++ + G G
Sbjct: 625 APPGRKREPPAQAVRFLPWATPGLEGAAVPQTLEKNRAGPEAEKRLRRGPE-EDGPWGPW 683
Query: 1017 DNE-KRSESQGT-------------------------APAFKQKLQDVHVAEGKKLLLQC 1050
D RS+ +G AP F+ LQ+V VA G +LL+C
Sbjct: 684 DRRGARSQGKGRRARPTSPELESSDDSYVSAGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743
Query: 1051 QVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQA 1110
++++PP + W +G L++ ++L EG ++ + +A D G Y A N+ GQA
Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQA 803
Query: 1111 ECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPK------ 1164
C+ +TV ++ +P S PP E T + P K P
Sbjct: 804 TCAASLTVRPGGSTSPFSSPITSDEEYLS--PPEEFPEPGETWPRTPTMKPSPSQNRRSS 861
Query: 1165 ---AAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE 1221
+ PP DQ VR G+ V + +V G +W++ R+ ++ + E +E
Sbjct: 862 DTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAE 921
Query: 1222 NG-SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1263
G +L ILAA + G YT N+ G+RQ + L V P+
Sbjct: 922 GGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964
Score = 111 bits (277), Expect = 7e-24
Identities = 82/256 (32%), Positives = 114/256 (44%), Gaps = 21/256 (8%)
Query: 443 VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAEL 499
+AP F+ +L+D V+EG+ C + GTP P +TW G P++ + R + G+ L
Sbjct: 1062 LAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSL 1121
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKS-----SRKSEYLLPVAPSKP--- 551
HI ED G Y A N GQ CSA + V E ++ S K E + P P +P
Sbjct: 1122 HIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKM-PSIPEEPEQG 1180
Query: 552 -----TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRG 606
+ P FL+ L DL+V + + QV+G P P + W HNG+ IQ S+D Q
Sbjct: 1181 ELERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYR 1240
Query: 607 TQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE----PHDGTQPWFISKPRSVT 662
H L V P+ G Y N G+ A L V + P DG R VT
Sbjct: 1241 DVHRLVFPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVT 1300
Query: 663 ASLGQSVLISCAIAGD 678
+ + AI D
Sbjct: 1301 LTWNPPRSLDMAIDPD 1316
Score = 99.8 bits (247), Expect = 2e-20
Identities = 74/244 (30%), Positives = 103/244 (42%), Gaps = 26/244 (10%)
Query: 31 EAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC-GIRGTF 89
EAP F +P +N+ + GA + + P PQV+WH++G + S GR LL G R T
Sbjct: 720 EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHT- 778
Query: 90 SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSK----TLGDRF 144
L++ D G Y ATN G LTV G P+ S + + F
Sbjct: 779 -LLLREARAADAGSYMATATNELGQATCAASLTVRPGGSTSPFSSPITSDEEYLSPPEEF 837
Query: 145 SAPAVETRP----------------SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
P ET P + PP F L V+EGQ S ++ G P
Sbjct: 838 PEPG-ETWPRTPTMKPSPSQNRRSSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEP 896
Query: 189 QPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAE 247
+P V+WL+ P++P R E + G+ L I + D G YTC VN G A
Sbjct: 897 KPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEAR 956
Query: 248 LSIQ 251
L ++
Sbjct: 957 LEVR 960
Score = 85.1 bits (209), Expect = 6e-16
Identities = 44/108 (40%), Positives = 61/108 (56%), Gaps = 4/108 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + D+EV G ARF +EG P P+++W+KD+ + ES H Y+E+ CSL+
Sbjct: 1485 PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEEN-ECSLV 1543
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1793
+ D YTC A N GE +C AEL V +T E EG GE+E+
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVEGVGEDED 1591
Score = 78.2 bits (191), Expect = 7e-14
Identities = 41/97 (42%), Positives = 59/97 (60%), Gaps = 1/97 (1%)
Query: 1684 KPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
+P + P F++ + D+EV+EG AARFDCKI G P P V W + ES + ++ D G
Sbjct: 1059 RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQD-GG 1117
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
SL I+ V +D+ Y AVN+ G+A C+A+L VE
Sbjct: 1118 LHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154
Score = 64.7 bits (156), Expect = 8e-10
Identities = 59/230 (25%), Positives = 85/230 (36%), Gaps = 37/230 (16%)
Query: 29 LTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH--RNGQPITSGGRFLLDCGIR 86
L EAPA + P + + EG A + E QV W R G + L
Sbjct: 1386 LEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDD 1444
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSA 146
+ L I V D G TC A N G + +V L + +
Sbjct: 1445 DQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-------------------- 1484
Query: 147 PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSAR 206
P+F + + V V G+ RF+ + G+P P + W K V L S+
Sbjct: 1485 --------------PRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSH 1530
Query: 207 VSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA 256
VS + L + D GVYTC N +G+ S AEL++ +A
Sbjct: 1531 VSFVYEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTA 1580
Score = 60.8 bits (146), Expect = 1e-08
Identities = 47/165 (28%), Positives = 71/165 (43%), Gaps = 18/165 (10%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ--PIQYARSTCEAGVAELHI 501
AP F LK+ AV G D L+ V GTP P + W +GQ P +C L +
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC------LWL 95
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLS 561
+ +D G Y+C+A+N G+ SC A +TV E S +E ++ + T + L+
Sbjct: 96 RRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAED--DISDVQGTQRLELRDDG 153
Query: 562 DLKVMDGSQVTMT--------VQVSGNPPPEVIWLHNGNEIQESE 598
G T+ V+G +V W +G + E E
Sbjct: 154 AFSTPTGGSDTLVGTSLDTPPTSVTGTSEEQVSWWGSGQTVLEQE 198
Score = 60.5 bits (145), Expect = 1e-08
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 10/206 (4%)
Query: 543 LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
LL P+ AP L + V++G ++TV + + +V+W + E+ +
Sbjct: 1379 LLEHGPTLEEAPAMLDKPDIVYVVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVY 1437
Query: 603 EQR---GTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR 659
E Q+ L I V D G TC A N G L + E P F S
Sbjct: 1438 ELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSVTLELAEA-----PRFESIME 1492
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWH 719
V G++ + + G P P + W +D + L ++ H + E+ +LV+
Sbjct: 1493 DVEVGAGETARFAVVVEGKPLPDIMWYKD-EVLLTESSHVSFVYEENECSLVVLSTGAQD 1551
Query: 720 AGQYEILLKNRVGECSCQVSLMLQNS 745
G Y +N GE SC+ L + ++
Sbjct: 1552 GGVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 59.3 bits (142), Expect = 3e-08
Identities = 52/252 (20%), Positives = 87/252 (34%), Gaps = 47/252 (18%)
Query: 1019 EKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF-IIL 1077
E R+ + + A LQDV V G+ L +C V+ + W G+ L+ +
Sbjct: 958 EVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKM 1017
Query: 1078 SQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRP 1137
+G C + + +D G+Y C + CS ++TV
Sbjct: 1018 HFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTV------------------- 1058
Query: 1138 KSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQP 1197
+ ++ P + ED +V G + K++GT P
Sbjct: 1059 --------------------------RPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPP 1092
Query: 1198 ITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT 1257
TW F ++ESE++++ L I E G Y + N G L
Sbjct: 1093 PVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQL- 1151
Query: 1258 VVDKPDPPAGTP 1269
V++P A P
Sbjct: 1152 YVEEPRTAASGP 1163
Score = 57.0 bits (136), Expect = 2e-07
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 10/129 (7%)
Query: 1651 KSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDC 1710
K PTSP +LES +D + A E+P P F ++++ V G+ C
Sbjct: 693 KGRRARPTSP----ELESSDDSYVS-----AGEEPLEAPVFEIPLQNVVVAPGADVLLKC 743
Query: 1711 KIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
I P P+V W KD ++R + + + + +L++ + D Y A N LG+
Sbjct: 744 IITANPPPQVSWHKDGSALRSEGRLLLRAEGERH-TLLLREARAADAGSYMATATNELGQ 802
Query: 1771 ATCTAELIV 1779
ATC A L V
Sbjct: 803 ATCAASLTV 811
Score = 57.0 bits (136), Expect = 2e-07
Identities = 52/228 (22%), Positives = 92/228 (40%), Gaps = 13/228 (5%)
Query: 903 PPPKPATPDFRSVLG--GKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA 960
PPP+ + S L G+ L AE + A+A ++ ++ A +G A
Sbjct: 749 PPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATAT-----NELGQA 803
Query: 961 KPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNEK 1020
A +L +P + P + + + EE + + + N +
Sbjct: 804 TCAASL----TVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRR 859
Query: 1021 RSESQGTAP-AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQ 1079
S++ AP FK L D V EG+ +++ +V +P + W N + ++ + +
Sbjct: 860 SSDTGSKAPPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEE 919
Query: 1080 -EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1126
EG LC + I A D G Y C A N+ G +C ++ V P S +
Sbjct: 920 AEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRS 967
Score = 55.1 bits (131), Expect = 6e-07
Identities = 32/96 (33%), Positives = 42/96 (43%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F ++ D V EG +++G P P V W ++ Q +R + + E G C L
Sbjct: 869 PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEE 1784
I D YTCKAVN G C A L V E
Sbjct: 929 ILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPE 964
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 7/96 (7%)
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
AP+FL+ L + V GS V + V VSG P P + W +G + L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAP-------EPSCLW 94
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
++ +D G Y+C A N G +AVLTV E D
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGD 130
Score = 53.1 bits (126), Expect = 2e-06
Identities = 51/178 (28%), Positives = 79/178 (44%), Gaps = 14/178 (7%)
Query: 948 AQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPM--GNAKPDENLKSASKEELKKDVKND 1005
A +G P + +E G++ P E+ + G ++P ++ K S L V+ +
Sbjct: 2512 AAQAGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKD-KGLSPPNLSASVQEE 2570
Query: 1006 VNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLN 1065
+ GH RSES P F KL+D + EG+ L C ++ P I W +
Sbjct: 2571 L----GHQYV-----RSESD-FPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKD 2620
Query: 1066 GKTLKTT-KFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
K+L++ II+S + +SI +A GLY+C A N G SC V V P
Sbjct: 2621 KKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVP 2678
Score = 52.8 bits (125), Expect = 3e-06
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 435 CEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARST 491
C + AP F S+++D V G+ V G P+P I W + + +
Sbjct: 1475 CSVTLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFV 1534
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 541
E L + +D G YTC A+N G+VSC A + VH +++ + E
Sbjct: 1535 YEENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSAQTAMEVE 1584
Score = 49.7 bits (117), Expect = 3e-05
Identities = 26/94 (27%), Positives = 43/94 (45%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
AP F+ ++DV V G+ V P I+W + L + + E + CS+
Sbjct: 1484 APRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECSLV 1543
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDA 1121
+ +D G+Y C A+N AG+ C ++ V A
Sbjct: 1544 VLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 49.3 bits (116), Expect = 3e-05
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 11/161 (6%)
Query: 1630 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLES-EEDVSQAFLEAVAEEKPHVK 1688
+AV G+ A + R +++G P+S L EK+ S E+ Q LE ++
Sbjct: 1137 SAVNTHGQAHCSAQLYVEEPRTAASG-PSSKL--EKMPSIPEEPEQGELERLSI------ 1187
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + ++DLEV A +C++ G P P + WF + I+ S ++ D + L+
Sbjct: 1188 PDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVH-RLV 1246
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1789
V Y N LG+A C A L V + G +G
Sbjct: 1247 FPAVGPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDG 1287
Score = 48.5 bits (114), Expect = 6e-05
Identities = 26/85 (30%), Positives = 43/85 (50%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
++D++V G A F+C + G D EV W + ++ + + + C L+++ V
Sbjct: 974 LQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHE 1033
Query: 1755 DDDAKYTCKAVNSLGEATCTAELIV 1779
DD YTCK + E TC+A L V
Sbjct: 1034 DDSGVYTCKLSTAKDELTCSARLTV 1058
Score = 48.1 bits (113), Expect = 7e-05
Identities = 34/124 (27%), Positives = 55/124 (44%), Gaps = 7/124 (5%)
Query: 129 KQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 188
K L P +S ++ + V + + PP F KL V+ EG+ C P
Sbjct: 2556 KGLSPPNLSASVQEELGHQYVRSE----SDFPPVFHIKLKDQVLLEGEAATLLCLPAACP 2611
Query: 189 QPQVTWLKGNVPL--QPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
P ++W+K L +PS + VS K+G Q+L I + G+Y C N G + S
Sbjct: 2612 APHISWMKDKKSLRSEPSV-IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670
Query: 247 ELSI 250
+++
Sbjct: 2671 TVAV 2674
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + +++ V GS R + G P P + WF+D Q + + +C +
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA-------PEPSCLWL 95
Query: 1749 ISDVCGDDDA-KYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEE 1793
CG DA Y+C A N G A+C A L V +E G+ E E++
Sbjct: 96 RR--CGAQDAGVYSCMAQNERGRASCEAVLTV--LEVGDSETAEDD 137
Score = 46.6 bits (109), Expect = 2e-04
Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS----TCEAGVAELH 500
P F LKD ++EG+ L C P P I+W+ + + ++ S +C+ G L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
I A G Y C A N LG ++ S V V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 45.1 bits (105), Expect = 6e-04
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 7/101 (6%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
AP F + L++ V G + L+ VS P ++ W +G+ L + E S +
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAP-----APEPSC--LW 94
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTK 1128
+ + +D G+Y C+A+N+ G+A C +TV + SE +
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTVLEVGDSETAE 135
Score = 45.1 bits (105), Expect = 6e-04
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR--FLLDC 83
++ L EAP F ++ + G TA+F V G P P + W+++ +T F+ +
Sbjct: 1478 TLELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYE- 1536
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGS 126
SLV+ + +D G YTC A N +G EL V +
Sbjct: 1537 --ENECSLVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAVHSA 1577
Score = 44.7 bits (104), Expect = 8e-04
Identities = 28/91 (30%), Positives = 38/91 (41%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F ++D ++EG AA C P P + W KD +S+R I +DG L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
I Y C A N LG T + + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 42.7 bits (99), Expect = 0.003
Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
AP F+ P +N + G+ + V G P+P + W R+GQ LL L
Sbjct: 42 APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQ--------LLPAPAPEPSCL 93
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTV 123
+ +D G Y+C A N G LTV
Sbjct: 94 WLRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 42.7 bits (99), Expect = 0.003
Identities = 60/258 (23%), Positives = 101/258 (39%), Gaps = 21/258 (8%)
Query: 1107 AGQAECSCQVTVDDAPASENTKAP-EMKSR---------RPKSSLPPVLGTESDATVKKK 1156
AG S + +A A+ + AP E +SR + K PP L A+V+++
Sbjct: 2515 AGATTPSAESLGSEASATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLS----ASVQEE 2570
Query: 1157 PAPK-TPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
+ ++ PP +DQ + GE+ L +WMK +K ++ +
Sbjct: 2571 LGHQYVRSESDFPPVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSV 2630
Query: 1216 KVENSENGSKL-TILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
+ + ++G +L +I A + H G Y N LGS + + V P A
Sbjct: 2631 IIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSCTVAVARVPGKLAPPEVPQTY 2690
Query: 1275 RSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELAT-CRSTSFNVQDLLPDHEYKF 1333
+ ++L L G S A +Y++E W +++ +NV L +F
Sbjct: 2691 QDTALVLWKPGDS----RAPCTYTLERRVDGESVWHPVSSGIPDCYYNVTHLPVGVTVRF 2746
Query: 1334 RVRAINVYGTSEPSQESE 1351
RV N G S SE
Sbjct: 2747 RVACANRAGQGPFSNSSE 2764
Score = 40.0 bits (92), Expect = 0.020
Identities = 26/93 (27%), Positives = 36/93 (38%)
Query: 1166 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1225
A P+ ED +V AGE+ V G W K + ES H+ EN
Sbjct: 1482 AEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENECS 1541
Query: 1226 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
L +L+ + G YT +N G + L V
Sbjct: 1542 LVVLSTGAQDGGVYTCTAQNLAGEVSCKAELAV 1574
Score = 38.9 bits (89), Expect = 0.045
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 9/91 (9%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQVLE 219
P F L V G R ++G PQP + W + G + P+ S L
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPAPEPSC--------LW 94
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ D GVY+C+ N G+AS A L++
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125
Score = 37.7 bits (86), Expect = 0.10
Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 8/89 (8%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
P F+ ++ G V + ++G P P++ W RDG+ L + L
Sbjct: 43 PVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFRDGQLLPAPA--------PEPSCLW 94
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSL 740
L++ AG Y + +N G SC+ L
Sbjct: 95 LRRCGAQDAGVYSCMAQNERGRASCEAVL 123
Score = 34.3 bits (77), Expect = 1.1
Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 2/91 (2%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
P F K + G++ + C A P P + W++D K+L + V + L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 712 LKKVQPWHAGQYEILLKNRVGE--CSCQVSL 740
+ + HAG YE N +G SC V++
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
Score = 33.1 bits (74), Expect = 2.5
Identities = 30/141 (21%), Positives = 54/141 (38%), Gaps = 20/141 (14%)
Query: 1150 DATVKKKPAPKTPPKAAM-------------PPQIIQFPEDQKVRAGESVELFGKVTGTQ 1196
DA + P+P PPK A P ++ ++ V AG V L V+GT
Sbjct: 11 DAGTRAPPSPGVPPKRAKVGAGGGAPVAVAGAPVFLRPLKNAAVCAGSDVRLRVVVSGTP 70
Query: 1197 PITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNL 1256
+ W + + + + S L + + G Y+ + +N+ G + L
Sbjct: 71 QPSLRWFRDGQLLPAP-------APEPSCLWLRRCGAQDAGVYSCMAQNERGRASCEAVL 123
Query: 1257 TVVDKPDPPAGTPCASDIRSS 1277
TV++ D SD++ +
Sbjct: 124 TVLEVGDSETAEDDISDVQGT 144
Score = 32.0 bits (71), Expect = 5.6
Identities = 29/101 (28%), Positives = 42/101 (41%), Gaps = 13/101 (12%)
Query: 1700 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH--FQIDYDEDGNCSLIISDVCGDDD 1757
VVEG A + + +VVW ++ E+R +++ +D L I V D
Sbjct: 1401 VVEGQPASVTVTFN-HVEAQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDM 1459
Query: 1758 AKYTCKAVNSLGEATCTA----------ELIVETMEEGEGE 1788
TC A N G TC+ E I+E +E G GE
Sbjct: 1460 GALTCTARNRHGTQTCSVTLELAEAPRFESIMEDVEVGAGE 1500
Score = 32.0 bits (71), Expect = 5.6
Identities = 19/91 (20%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 612
P+F L D +++G T+ + P P + W+ + ++ E + + L
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
I G Y C A N G + + + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 158 bits (399), Expect = 5e-38
Identities = 99/324 (30%), Positives = 156/324 (48%), Gaps = 56/324 (17%)
Query: 1391 VSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLHHP 1450
+SDF+++E LG G V+R +K T+K +A K K +K+ +R EI ++ L HP
Sbjct: 42 LSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLK--KTVDKKIVRTEIGVLLRLSHP 99
Query: 1451 KLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQ 1510
+++ + FE I +VLE+V+GGELF+RI+++ + +ER+ ++QI E V Y+H+
Sbjct: 100 NIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGY-YSERDAADAVKQILEAVAYLHEN 158
Query: 1511 GIVHLDLKPENIMCVNKT-GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPI 1569
GIVH DLKPEN++ +K+ DFGL++ +E+ +K + GTP + APE++
Sbjct: 159 GIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAY 218
Query: 1570 GYATDMWSIGVICYIL-------------------------------------------- 1585
G DMWS+G+I YIL
Sbjct: 219 GPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVR 278
Query: 1586 --------NRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGR 1637
RL Q LQHPW+ N ++ +++++ ARRK + AV A R
Sbjct: 279 KLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSR 338
Query: 1638 LSSMAMISGLSGRKSSTGSPTSPL 1661
L S + G SP+
Sbjct: 339 LGSASSSHGSIQESHKASRDPSPI 362
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 158 bits (399), Expect = 5e-38
Identities = 93/316 (29%), Positives = 158/316 (50%), Gaps = 55/316 (17%)
Query: 1389 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKE-NIRQEISIMNCL 1447
+ + D YD + LG+G F +V +K+T+K+ A K + + KE ++ EI++++ +
Sbjct: 14 EDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKI 73
Query: 1448 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1507
HP +V D +E ++ +++++VSGGELF+RI+++ F TER+ + + Q+ + V+Y+
Sbjct: 74 KHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGF-YTERDASRLIFQVLDAVKYL 132
Query: 1508 HKQGIVHLDLKPENIMCVN-KTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1566
H GIVH DLKPEN++ + ++I + DFGL++ + L GTP +VAPEV+
Sbjct: 133 HDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQ 192
Query: 1567 EPIGYATDMWSIGVICYIL----------------------------------------- 1585
+P A D WSIGVI YIL
Sbjct: 193 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDF 252
Query: 1586 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1634
R C Q LQHPW+ DT + + +++KK A+ KW++ NA
Sbjct: 253 IRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAV 312
Query: 1635 IGRLSSMAMISGLSGR 1650
+ + + + + G+
Sbjct: 313 VRHMRKLQLGTSQEGQ 328
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 155 bits (392), Expect = 3e-37
Identities = 173/724 (23%), Positives = 276/724 (38%), Gaps = 140/724 (19%)
Query: 53 EGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
E R G P PQ+ W +NG P+ L G ++ A D YTC A+N +
Sbjct: 3363 ECRATGTPPPQINWLKNGLPLPLSSHIRLLAA--GQVIRIVRA-QVSDVAVYTCVASNRA 3419
Query: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLG--RV 170
G L V FA PP +G +
Sbjct: 3420 GVDNKHYNLQV---FA-------------------------------PPNMDNSMGTEEI 3445
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V +G +C G P P + WL+ PL A ++VS +GM VL++ +D G
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVST-HGM-VLQLLKAETEDSGK 3503
Query: 231 YTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
YTC+ N +G+ S L + + S+ +E++ +++ +L +
Sbjct: 3504 YTCIASNEAGEVSKHFILKV----------LEPPHINGSEEHEEISVIVNNPLELTCI-- 3551
Query: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
A+ P P K+ KD R PQT +Q L+ +
Sbjct: 3552 -------------------ASGIPAP----KMTWMKDG-RPLPQTDQVQTLGGGEVLRIS 3587
Query: 351 RVQPEPRAPGLGVLS-PSGEERKR-----PAPPRPATF--PTRQPGLGSQDVVSKAANRR 402
Q E + S P+G++ K PP A P L ++ V + +
Sbjct: 3588 TAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDA 3647
Query: 403 IP-------MEGQRDSAFPKFESKPQSQEVKENQ-----TVKFRC-----------EGLA 439
+P G+R A P+ + ++ N T + C E +
Sbjct: 3648 VPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFIL 3707
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI--QYAR-STCEAGV 496
+ V P+ + ++ + VL+C G P PRITW +G + +AR S E G
Sbjct: 3708 TVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF 3767
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 556
LHIQ A D G Y C+A NA G R+ + + V PS P
Sbjct: 3768 --LHIQSAHVTDTGRYLCMATNAAGT-------------DRRRIDLQVHVPPSIAPGP-- 3810
Query: 557 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
+++ V+ Q T+ + +G P P + W NG+ + ++ + + + SL I
Sbjct: 3811 ----TNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP 3866
Query: 617 FPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA 676
+DT TY C N AG+ + LTVQ P P +P + +I+C +
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTVQVP-----PSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 677 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSC 736
G PFP++HW ++G L + +L + + L Q HAG+Y + +N G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILA---TQLNHAGRYTCVARNAAGSAHR 3978
Query: 737 QVSL 740
V+L
Sbjct: 3979 HVTL 3982
Score = 150 bits (379), Expect = 1e-35
Identities = 185/792 (23%), Positives = 294/792 (37%), Gaps = 146/792 (18%)
Query: 8 ASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWH 67
A+ + T+ + D R + + P+ P + + + A A G P P + W
Sbjct: 3872 ATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWT 3931
Query: 68 RNG---QPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
+NG P G R L I + + HA G+YTC A N +G+ V L V
Sbjct: 3932 KNGIRLLPRGDGYRILSSGAIEILATQLNHA------GRYTCVARNAAGSAHRHVTLHVH 3985
Query: 125 GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI 184
P ++ +PS + L ++ C+
Sbjct: 3986 --------------------EPPVIQPQPS-------ELHVILNNPIL-------LPCEA 4011
Query: 185 TGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASM 244
TG P P +TW K + + S R +G L+I ++D G Y C+ N +G A
Sbjct: 4012 TGTPSPFITWQKEGINVNTSGRNHAVLPSGG--LQISRAVREDAGTYMCVAQNPAGTALG 4069
Query: 245 SAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGG 304
+L++Q V VIS K + + A K S G
Sbjct: 4070 KIKLNVQ-----------------------VPPVISPHLK-EYVIAVDKPITLSCEADGL 4105
Query: 305 SPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPR------A 358
PP + KD A + Q+ SS +LQ A VQP A
Sbjct: 4106 PPP-------------DITWHKDG--RAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMA 4150
Query: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIP---MEGQRDSAF-- 413
+ S + + PPR + + + IP + ++D+
Sbjct: 4151 ANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLA 4210
Query: 414 ---PKFESKPQSQEVKENQTVK----FRCEG-----------LAVMEVAPSFSSVLKDCA 455
K+ ++P + + EN ++ + C + V P+F+ + D +
Sbjct: 4211 NLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVS 4270
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCL 515
+ +G+ L C G P+P++TW N I A G +EL I+ ED GTY C
Sbjct: 4271 LNKGEQLRLSCKATGIPLPKLTWTFNNNIIP-AHFDSVNGHSELVIERVSKEDSGTYVCT 4329
Query: 516 AENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTV 575
AEN++G V +V V E K +Y PS P+ G +
Sbjct: 4330 AENSVGFVKAIGFVYVKEPPVF-KGDY-----PSNWIEPL------------GGNAILNC 4371
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
+V G+P P + W G +I+ S G SL I ED G YTC A N AG V
Sbjct: 4372 EVKGDPTPTIQWNRKGVDIEISHRIRQLGNG---SLAIYGTVNEDAGDYTCVATNEAGVV 4428
Query: 636 RTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKD 695
LT+Q P P +P + G ++++C G+P PT+ W R G ++ D
Sbjct: 4429 ERSMSLTLQSP-----PIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWD 4483
Query: 696 TGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGRE 755
VL N +L + Q ++E + +N +G +V +++Q +
Sbjct: 4484 -DRVNVLSNN---SLYIADAQKEDTSEFECVARNLMGSVLVRVPVIVQVHG--GFSQWSA 4537
Query: 756 PASCEDLCGGGV 767
+C CG G+
Sbjct: 4538 WRACSVTCGKGI 4549
Score = 144 bits (363), Expect = 8e-34
Identities = 168/717 (23%), Positives = 284/717 (39%), Gaps = 88/717 (12%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
L P+ + IK T E P ++W+++GQP+ S ++ G +L I
Sbjct: 2679 LSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDH--VNIAANG-HTLQIKEA 2735
Query: 97 HEEDRGKYTCEATNGSGARQV--TVELTVEGSFAK--QLGQPVVSKTLGDRFSAPAVETR 152
D G+YTC A+N +G ++ V + V SF K ++G + + G+
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE---------- 2785
Query: 153 PSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK 212
+ V+ + + C+ P P +TW K PL S +V +
Sbjct: 2786 ---------------AKDVIINNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILP- 2828
Query: 213 NGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVR 272
G +VL+I +D G YTC+ VN +G+ S+ ++ + K NSD+
Sbjct: 2829 -GGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRV--------LVPPIIKGANSDLP 2879
Query: 273 KEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP-------PWAANSQPQPPRESKLESC 325
+EVT +++K + ++ L + + + +S Q+ G P + +N + +++
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPR-NSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDI 2938
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGV-----LSPSGEERKRPAPPRPA 380
A T K ++ + P++ L V +S + E P PP +
Sbjct: 2939 GRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP-PPDLS 2997
Query: 381 TFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAV 440
QP + + + R + + + S ++ +Q + + KF
Sbjct: 2998 WLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKK--KFSLTVYVP 3055
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-- 498
+ S L V EG L+C P P ITW NG+ I ST +A+
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMI--TESTHVEILADGQ 3113
Query: 499 -LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFL 557
LHI+ A D G Y C A N G+ + + V+ +P + P + +
Sbjct: 3114 MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVY-----------VPPSIEGPEREVIV 3162
Query: 558 QGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVF 617
+ +S + VT+T +G PPP + WL N I+ S+ L I
Sbjct: 3163 ETIS-------NPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQ 3215
Query: 618 PEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAG 677
D+G YTC A N G+ + L++Q P P V+ LG++V + C G
Sbjct: 3216 HSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAG---AEIPSDVSVLLGENVELVCNANG 3272
Query: 678 DPFPTVHWLRDGKALCK-DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
P P + WL+DGK + +T V N TL + G+Y + N GE
Sbjct: 3273 IPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 143 bits (361), Expect = 1e-33
Identities = 164/717 (22%), Positives = 268/717 (37%), Gaps = 144/717 (20%)
Query: 58 GYPEPQVTWHRNGQPI-TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQ 116
G P P +TW ++ QP+ T+ G + R L I ED G+YTC ATN +G Q
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGR---VLQIAKTLLEDAGRYTCVATNAAGETQ 1908
Query: 117 VTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQ 176
++L V P++E A K+ V
Sbjct: 1909 QHIQLHVH--------------------EPPSLED------------AGKMLNETVLVSN 1936
Query: 177 MGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
+ CK G P P +TW K N L S S++ N Q+++I D G+Y C+ +
Sbjct: 1937 PVQLECKAAGNPVPVITWYKDNRLL--SGSTSMTFLNRGQIIDIESAQISDAGIYKCVAI 1994
Query: 237 NGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKN 296
N +G + L + S + S N+ V V N + E + + A + +
Sbjct: 1995 NSAGATELFYSLQVHVAPSISGS--------NNMVAVVVNNPVRLECEARGIPAPSLT-- 2044
Query: 297 CSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEP 356
W + P + S + + +L TS+ I+
Sbjct: 2045 -----------WLKDGSP-------VSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAV 2086
Query: 357 RAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKF 416
A G E++R R P +G + VS ++ + + Q D+ P
Sbjct: 2087 NAAG---------EKQRDIDLRVYVPPNI---MGEEQNVSVLISQAVELLCQSDAIPPPT 2134
Query: 417 ES---------KPQSQEVKENQTV------------KFRCEGLAV-----------MEVA 444
+ K + EN++V ++ CE V + V
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVP 2194
Query: 445 PSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGVAEL 499
P+ S L VIEG L C G P P + W G P+ R +G +L
Sbjct: 2195 PNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQL 2254
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I A D Y+C+A N G KK Y+ P + + P
Sbjct: 2255 QISIAEKSDAALYSCVASNVAGTA----------KKEYNLQVYIRPTITNSGSHP----- 2299
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPE 619
+++ V G +++ +V G PPP V W+ +G+ + +++ G H L ++ +
Sbjct: 2300 -TEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG--HILQLKNIHVS 2356
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK---PRSVTASLGQSVLISCAIA 676
DTG Y C A N AG + L+V P P I P +++ SV ++C +
Sbjct: 2357 DTGRYVCVAVNVAGMTDKKYDLSVHAP-----PSIIGNHRSPENISVVEKNSVSLTCEAS 2411
Query: 677 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
G P P++ W +DG + + +L + L+ ++ AGQY +++N GE
Sbjct: 2412 GIPLPSITWFKDGWPVSL-SNSVRILSGGRMLRLMQTTME--DAGQYTCVVRNAAGE 2465
Score = 131 bits (329), Expect = 7e-30
Identities = 168/729 (23%), Positives = 266/729 (36%), Gaps = 123/729 (16%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG--RFLLDCGIRGTFSLVIHAV 96
P + + +A E G P P+ +W ++GQP+ +FL + I L I
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI-----LQILNT 2933
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
D G+Y C A N +G+ + L V PS+
Sbjct: 2934 QITDIGRYVCVAENTAGSAKKYFNLNVH--------------------------VPPSVI 2967
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
G K + V +C+++G P P ++WLK P++ + + G +
Sbjct: 2968 GP-------KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVP--GGR 3018
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVT 276
L+I D G YTC+ +N +G++ L++ +V + + V
Sbjct: 3019 TLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV---------YVPPSIKDHDSESLSVV 3069
Query: 277 NVISKESKLDSLEAAAKSKNCSSPQRGGSPP----WAANSQPQPPRESKLESCKDSPRTA 332
NV E + S C S PP W N + + +E D
Sbjct: 3070 NV---------REGTSVSLECES---NAVPPPVITWYKNGR-MITESTHVEILADGQMLH 3116
Query: 333 PQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSP---SGEERKRPAPP--RPATFPTRQP 387
+ + T + + + L V P G ER+ P T
Sbjct: 3117 IKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDAT 3176
Query: 388 GLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRC-----EGLAV-- 440
G+ + ++RI + SK Q + + + + C EG A
Sbjct: 3177 GIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKY 3236
Query: 441 ----MEVAPSFSS--VLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARST 491
++V PS + + D +V+ G++ L C+ G P P I WL +G+PI + R
Sbjct: 3237 YFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIR 3296
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKP 551
A + L+I AL D G YTC+A N G+ E + + Y+ P
Sbjct: 3297 VSANGSTLNIYGALTSDTGKYTCVATNPAGE----------EDRIFNLNVYVTPTIRGNK 3346
Query: 552 TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSL 611
L L D + + + + +G PPP++ WL NG + S H +
Sbjct: 3347 DEAEKLMTLVD------TSINIECRATGTPPPQINWLKNGLPLPLSS--HIRLLAAGQVI 3398
Query: 612 CIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHD-----GTQPWFISKPRSVTASLG 666
I D YTC A N AG L V P + GT+ +T G
Sbjct: 3399 RIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTE--------EITVLKG 3450
Query: 667 QSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEIL 726
S ++C G P P++ WLRDG+ L D H V + V L L K + +G+Y +
Sbjct: 3451 SSTSMACITDGTPAPSMAWLRDGQPLGLD-AHLTVSTHGMV--LQLLKAETEDSGKYTCI 3507
Query: 727 LKNRVGECS 735
N GE S
Sbjct: 3508 ASNEAGEVS 3516
Score = 124 bits (310), Expect = 1e-27
Identities = 158/716 (22%), Positives = 275/716 (38%), Gaps = 114/716 (15%)
Query: 44 IKEGATAKFEGRVRGYPEPQVTWHRNGQP--------ITSGGRFLLDCGIRGTFSLVIHA 95
+KE + V G P P++TWH++GQP I SGGRFL I
Sbjct: 2491 VKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQ-----------ITN 2539
Query: 96 VHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSI 155
V G+YTC A++ +G + + L V F +P + +
Sbjct: 2540 VQVPHTGRYTCLASSPAGHKSRSFSLNV--------------------FVSPTIA---GV 2576
Query: 156 WGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
+ P+ T V C+ P +TW K PL+ + + + G
Sbjct: 2577 GSDGNPEDVT------VILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP--GG 2628
Query: 216 QVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEV 275
+ L+I +D+ G Y+C+ N +G+ E+ + N+ + + +V+ +V
Sbjct: 2629 RTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKV 2688
Query: 276 TNVISKESKLDSLEAAAKS--KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAP 333
N ++ E + ++ +A+ S K+ + AAN +E+++ A
Sbjct: 2689 NNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVAS 2748
Query: 334 QTPVLQKTSSSITLQAARVQPE-PRAPGLGVLSPSGE-----------------ERKRPA 375
+ + +Q V P + +G + +G E
Sbjct: 2749 NIAGEDELDFDVNIQ---VPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAP 2805
Query: 376 PPRPATFPTRQPGLGSQDVVSKAANR--RIPMEGQRDSAFPKFESKPQSQEVKENQTVKF 433
PP + P S V+ R +IP D+ + ++ E ++++
Sbjct: 2806 PPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGE----DSLQY 2861
Query: 434 RCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP-IQYARSTC 492
L + + S + ++ V+ + +++C G+P PR +W +GQP ++
Sbjct: 2862 DVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF 2921
Query: 493 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
+ L I + D G Y C+AEN G + VH V PS
Sbjct: 2922 LSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH-------------VPPS--- 2965
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
+ +L V+ + +++T +VSG PPP++ WL N I+ + + G +L
Sbjct: 2966 --VIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGG--RTLQ 3021
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP-----HDGTQPWFISKPRSVTASLGQ 667
I D G YTC A N AGE + + LTV P HD V G
Sbjct: 3022 IIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDS------ESLSVVNVREGT 3075
Query: 668 SVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
SV + C P P + W ++G+ + + T H E+L + + L +KK + GQY
Sbjct: 3076 SVSLECESNAVPPPVITWYKNGRMITEST-HVEILADGQM--LHIKKAEVSDTGQY 3128
Score = 116 bits (290), Expect = 2e-25
Identities = 144/690 (20%), Positives = 233/690 (33%), Gaps = 135/690 (19%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAV 96
P + + G V+ P P +TW + Q I+ S L G S+ I
Sbjct: 1086 PVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG-----SMKITET 1140
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
D G Y C ATN +G V+L V
Sbjct: 1141 RTSDSGMYLCVATNIAGNVTQAVKLNVH-------------------------------- 1168
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
PPK + V+ GQ C G P P +TW KG + VS +G
Sbjct: 1169 --VPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG-- 1224
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVT 276
L I D G+YTC+ N I G D + + T D+
Sbjct: 1225 TLSIDQATPSDAGIYTCVATN------------IAGTDETEITLHVQEPPTVEDLEPPYN 1272
Query: 277 NVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTP 336
+ +E +K P + W N + RE + +D
Sbjct: 1273 TTFQERVANQRIEFPCPAKGTPKP----TIKWLHNGRELTGREPGISILEDGT------- 1321
Query: 337 VLQKTSSSITLQAARVQPEPRAPGLGV-LSPSGE-ERKRPAPPR-PATFPTRQPGLGSQD 393
L A V P + V ++ +G ERK P ++
Sbjct: 1322 ---------LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSV 1372
Query: 394 VVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTV-----------------KFRCE 436
++++ N +EG ++ Q E QTV ++ C+
Sbjct: 1373 LLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCK 1432
Query: 437 GLAVMEVAPSFSSV-------------LKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ 483
+ + + + ++ + +V+ +D L+C V+GTP P I W +G+
Sbjct: 1433 AINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGK 1492
Query: 484 PIQYARSTCEA--GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSE 541
P+ E LH+++A D G Y C NA G+ + +T++
Sbjct: 1493 PLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIY--------- 1543
Query: 542 YLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH 601
+ PS + +D+ V+ S + + + G P P + W +G I S
Sbjct: 1544 ----IPPSIKGGNV----TTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQAL 1595
Query: 602 FEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH--DGTQPWFISKPR 659
+ +G L I D+ TYTC N AG + V P +G ++ P
Sbjct: 1596 YIDKG--QYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGN----LATPL 1649
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDG 689
+ + S+ + C AG+P P + WL+DG
Sbjct: 1650 NKQVVIAHSLTLECKAAGNPSPILTWLKDG 1679
Score = 108 bits (269), Expect = 6e-23
Identities = 80/292 (27%), Positives = 120/292 (41%), Gaps = 28/292 (9%)
Query: 452 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHG 510
++ +VI L C G P P++TW+ +G+P+ G E L I A ED G
Sbjct: 3536 EEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGEVLRISTAQVEDTG 3595
Query: 511 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 570
YTCLA + G V VH +P + P D+ V+ Q
Sbjct: 3596 RYTCLASSPAGDDDKEYLVRVH-----------VPPNIAGTDEP------RDITVLRNRQ 3638
Query: 571 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 630
VT+ + PPP + WL NG +Q + G L I DT YTC A N
Sbjct: 3639 VTLECKSDAVPPPVITWLRNGERLQATPRVRILSGG--RYLQINNADLGDTANYTCVASN 3696
Query: 631 SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
AG+ + +LTV P P P+S+ L +S ++ C G P P + W +DG
Sbjct: 3697 IAGKTTREFILTVNVP-----PNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGA 3751
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 742
L + + +L+N L ++ G+Y + N G ++ L +
Sbjct: 3752 VLAGNHARYSILENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 106 bits (265), Expect = 2e-22
Identities = 83/283 (29%), Positives = 117/283 (41%), Gaps = 23/283 (8%)
Query: 452 KDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST-CEAGVAELHIQDALPEDHG 510
++ +V+E L C G P+P ITW +G P+ + S +G L + ED G
Sbjct: 2394 ENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAG 2453
Query: 511 TYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQ 570
YTC+ NA G+ E+K S + P + T L D+KV +
Sbjct: 2454 QYTCVVRNAAGE----------ERKIFGLSVLVPPHIVGENT-------LEDVKVKEKQS 2496
Query: 571 VTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWN 630
VT+T +V+GNP PE+ W +G +QE E H G L I V TG YTC A +
Sbjct: 2497 VTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG--RFLQITNVQVPHTGRYTCLASS 2554
Query: 631 SAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
AG L V P VT L + C P T+ W +DG
Sbjct: 2555 PAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGT 2614
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
L + + +L TL + Q +AG+Y + N GE
Sbjct: 2615 PL-ESNRNIRILPGGR--TLQILNAQEDNAGRYSCVATNEAGE 2654
Score = 103 bits (258), Expect = 1e-21
Identities = 79/286 (27%), Positives = 114/286 (39%), Gaps = 34/286 (11%)
Query: 453 DCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQDALPEDH 509
+ +V+ G++ L C V+ P P ITW Q P + +G + I + D
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG--SMKITETRTSDS 1145
Query: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
G Y C+A N G V+ + + VH P +G LKV G
Sbjct: 1146 GMYLCVATNIAGNVTQAVKLNVH-------------------VPPKIQRGPKHLKVQVGQ 1186
Query: 570 QVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAW 629
+V + G P P + W G+ + + H +L I + P D G YTC A
Sbjct: 1187 RVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN--PDGTLSIDQATPSDAGIYTCVAT 1244
Query: 630 NSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWL 686
N AG T+ L VQEP D P+ + V Q + C G P PT+ WL
Sbjct: 1245 NIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVA---NQRIEFPCPAKGTPKPTIKWL 1301
Query: 687 RDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
+G+ L +L ED LV+ V P+ G+Y + N G
Sbjct: 1302 HNGRELTGREPGISIL--EDGTLLVIASVTPYDNGEYICVAVNEAG 1345
Score = 103 bits (256), Expect = 2e-21
Identities = 81/308 (26%), Positives = 131/308 (42%), Gaps = 34/308 (11%)
Query: 440 VMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI---QYARSTCEAGV 496
V ++ P +++ ++ + Q C +GTP P I WL NG+ + + S E G
Sbjct: 1264 VEDLEPPYNTTFQER--VANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT 1321
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 556
L I P D+G Y C+A N G + VH + PV K
Sbjct: 1322 L-LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVH----------VPPVIKDK------ 1364
Query: 557 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
+ ++++ V+ + +V G P P ++W + ++ ES G L +
Sbjct: 1365 -EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGK--ILKLFRA 1421
Query: 617 FPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISK--PRSVTASLGQSVLISCA 674
PED G Y+C+A N AG + + V P P I P V+ L + V + C
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDVLVP-----PTIIGTNFPNEVSVVLNRDVALECQ 1476
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
+ G PFP +HW +DGK L + E+L V L LK + G+Y+ + N G+
Sbjct: 1477 VKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV--LHLKNARRNDKGRYQCTVSNAAGKQ 1534
Query: 735 SCQVSLML 742
+ + L +
Sbjct: 1535 AKDIKLTI 1542
Score = 101 bits (251), Expect = 7e-21
Identities = 80/295 (27%), Positives = 117/295 (39%), Gaps = 28/295 (9%)
Query: 448 SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST--CEAGVAELHIQDAL 505
SS L + V++ + LQC G P P ITWL + QP+ A+ ++ L I L
Sbjct: 1830 SSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTL 1889
Query: 506 PEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKV 565
ED G YTC+A NA G+ + VHE S + +L + V
Sbjct: 1890 LEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKML-----------------NETV 1932
Query: 566 MDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYT 625
+ + V + + +GNP P + W + + S F RG + I+ D G Y
Sbjct: 1933 LVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYK 1990
Query: 626 CEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHW 685
C A NSAG L V P V + V + C G P P++ W
Sbjct: 1991 CVAINSAGATELFYSLQVH-----VAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Query: 686 LRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSL 740
L+DG + + +VL + L L Q G+Y + N GE + L
Sbjct: 2046 LKDGSPVSSFSNGLQVLSGGRI--LALTSAQISDTGRYTCVAVNAAGEKQRDIDL 2098
Score = 98.6 bits (244), Expect = 5e-20
Identities = 72/243 (29%), Positives = 103/243 (42%), Gaps = 26/243 (10%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDA 504
P + + K+ + G + + CS G P P+I W +N I + L I++A
Sbjct: 612 PKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNA 671
Query: 505 LPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK 564
P+D G Y CLA N+ G K + Y+ AP + S+L
Sbjct: 672 APKDAGIYGCLASNSAGT-----------DKQNSTLRYI--------EAPKLMVVQSELL 712
Query: 565 VMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTY 624
V G M + SG PPP+V W E++ S + L IQE D G Y
Sbjct: 713 VALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDP--LLGLLKIQETQDLDAGDY 770
Query: 625 TCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVH 684
TC A N AG + L V G+ P FI +P V+ +G +V + C + G P PT+
Sbjct: 771 TCVAINEAGRATGKITLDV-----GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIK 825
Query: 685 WLR 687
W R
Sbjct: 826 WRR 828
Score = 98.6 bits (244), Expect = 5e-20
Identities = 76/290 (26%), Positives = 126/290 (43%), Gaps = 33/290 (11%)
Query: 449 SVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPE 507
+V D +V+ L+C RG P+P ITW +GQPI + + LHI A
Sbjct: 1552 NVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVS 1611
Query: 508 DHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMD 567
D TYTC N G +KS Y+ P+ P+ + +V+
Sbjct: 1612 DSATYTCHVANVAGTA----------EKSFHVDVYVPPMIEGNLATPL------NKQVVI 1655
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTC 626
+T+ + +GNP P + WL +G ++ +++ E G + + QE+ D G Y C
Sbjct: 1656 AHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEI---DRGQYIC 1712
Query: 627 EAWNSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
A + AGE + + V P G + + + + + C + G P PT+
Sbjct: 1713 VATSVAGEKEIKYEVDVLVPPAIEGGDETSYF------IVMVNNLLELDCHVTGSPPPTI 1766
Query: 684 HWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
WL+DG+ + + G F++L N LV+ + Q + G Y + N G+
Sbjct: 1767 MWLKDGQLIDERDG-FKILLNGR--KLVIAQAQVSNTGLYRCMAANTAGD 1813
Score = 97.4 bits (241), Expect = 1e-19
Identities = 83/311 (26%), Positives = 134/311 (43%), Gaps = 45/311 (14%)
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST-CEAGVAELHIQDALPEDHGTYTC 514
V+ L+C G P P +TWL +G P++ + EAG +L I A D G Y C
Sbjct: 1653 VVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQEIDRGQYIC 1712
Query: 515 LAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLK---VMDGSQV 571
+A + G EK+ + + L+P A ++G + VM + +
Sbjct: 1713 VATSVAG-----------EKEIKYEVDVLVPPA---------IEGGDETSYFIVMVNNLL 1752
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
+ V+G+PPP ++WL +G I E + F G + L I + +TG Y C A N+
Sbjct: 1753 ELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRK--LVIAQAQVSNTGLYRCMAANT 1810
Query: 632 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLG-QSVLISCAIAGDPFPTVHWLRDGK 690
AG+ + + +TV P P S S + + V + C G P P++ WL+D +
Sbjct: 1811 AGDHKKEFEVTVHVP-----PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQ 1865
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARAL 750
+ G+ ++ + V L + K AG+Y + N GE + L +
Sbjct: 1866 PVNTAQGNLKIQSSGRV--LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHV-------- 1915
Query: 751 PRGREPASCED 761
EP S ED
Sbjct: 1916 ---HEPPSLED 1923
Score = 96.7 bits (239), Expect = 2e-19
Identities = 82/305 (26%), Positives = 127/305 (41%), Gaps = 24/305 (7%)
Query: 441 MEVAPSFSSVLKDCAVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQYARSTCEA-GVAE 498
+ V PS + + +F+ L C V G P P ++WL N QPI+ +T G
Sbjct: 2960 VHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT 3019
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQ 558
L I A D G YTC+A N G+ +TV+ S + + +
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDS---------------E 3064
Query: 559 GLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP 618
LS + V +G+ V++ + + PPP + W NG I ES H E L I++
Sbjct: 3065 SLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITEST--HVEILADGQMLHIKKAEV 3122
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGD 678
DTG Y C A N AG L V P P + + ++ V ++C G
Sbjct: 3123 SDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGP----EREVIVETISNPVTLTCDATGI 3178
Query: 679 PFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738
P PT+ WL++ K + +++ EV L + + Q +G Y + N G+
Sbjct: 3179 PPPTIAWLKNHKRI-ENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYY 3237
Query: 739 SLMLQ 743
L +Q
Sbjct: 3238 FLSIQ 3242
Score = 93.6 bits (231), Expect = 2e-18
Identities = 75/268 (27%), Positives = 106/268 (39%), Gaps = 27/268 (10%)
Query: 427 ENQTVKFRCEGLAVME--VAPSFSSVLKDCAVIEGQDFVLQCSV-RGTPVPRITWLLNGQ 483
ENQ K + E + VAP VIEGQ L C++ G P+P W+ N
Sbjct: 870 ENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSA 929
Query: 484 PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYL 543
+ LHI+ +D G YTC+A N G + + V VH
Sbjct: 930 MLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH----------- 978
Query: 544 LPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFE 603
P G L ++G VT+ + SGNP P VIW G I S
Sbjct: 979 --------VLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF-- 1028
Query: 604 QRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ-EPHDGTQPWFIS--KPRS 660
G SL + E++G Y C A N+AG + + LTV P +S KP
Sbjct: 1029 SAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVE 1088
Query: 661 VTASLGQSVLISCAIAGDPFPTVHWLRD 688
++ G+ V + C + P P + W ++
Sbjct: 1089 ISVLAGEEVTLPCEVKSLPPPIITWAKE 1116
Score = 90.1 bits (222), Expect = 2e-17
Identities = 71/273 (26%), Positives = 112/273 (41%), Gaps = 30/273 (10%)
Query: 464 LQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE-LHIQDALPEDHGTYTCLAENALGQ 522
++C GTP P+I WL NG P+ + + + I A D YTC+A N G
Sbjct: 3362 IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGV 3421
Query: 523 VSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPP 582
K L AP + G ++ V+ GS +M G P
Sbjct: 3422 --------------DNKHYNLQVFAPPNMDNSM---GTEEITVLKGSSTSMACITDGTPA 3464
Query: 583 PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLT 642
P + WL +G + G L E ED+G YTC A N AGEV +L
Sbjct: 3465 PSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAET--EDSGKYTCIASNEAGEVSKHFILK 3522
Query: 643 VQEPH--DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFE 700
V EP +G++ + ++ + + ++C +G P P + W++DG+ L T +
Sbjct: 3523 VLEPPHINGSE-----EHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPL-PQTDQVQ 3576
Query: 701 VLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
L +V + +V+ G+Y L + G+
Sbjct: 3577 TLGGGEVLRISTAQVE--DTGRYTCLASSPAGD 3607
Score = 89.7 bits (221), Expect = 2e-17
Identities = 83/314 (26%), Positives = 131/314 (41%), Gaps = 28/314 (8%)
Query: 437 GLAVMEVAPSF--SSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS-TCE 493
GL+V+ V P + L+D V E Q L C V G PVP ITW +GQP+Q +
Sbjct: 2471 GLSVL-VPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII 2529
Query: 494 AGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 553
+G L I + G YTCLA + G H+ +S + L V S A
Sbjct: 2530 SGGRFLQITNVQVPHTGRYTCLASSPAG----------HKSRS-----FSLNVFVSPTIA 2574
Query: 554 PIFLQG-LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
+ G D+ V+ S ++ + PP + W +G ++ + + G +L
Sbjct: 2575 GVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG--RTLQ 2632
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSVTASLGQSV 669
I ++ G Y+C A N AGE+ + V P + G P+ V + ++
Sbjct: 2633 ILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKN 729
+ C P ++ W +DG+ L K H + N TL +K+ Q G+Y + N
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPL-KSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASN 2749
Query: 730 RVGECSCQVSLMLQ 743
GE + +Q
Sbjct: 2750 IAGEDELDFDVNIQ 2763
Score = 87.0 bits (214), Expect = 1e-16
Identities = 135/614 (21%), Positives = 219/614 (35%), Gaps = 99/614 (16%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN--VPLQPSARVSVSEKNGMQV 217
PP V V G+ +C I +TW + + V L AR+
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS--- 575
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSA-----NRSFVRETK------A 266
LE+ V +D G Y C+V + G ++ S L++Q N+SF ++ A
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSA 635
Query: 267 TNSDVRKEVTNV-----ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
T K V + + + KN + G A+NS + S
Sbjct: 636 TGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNST 695
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPAT 381
L ++P+ L IT+ + G+ P + K RP+T
Sbjct: 696 LRYI-EAPKLMVVQSELLVALGDITVMECKTS--------GIPPPQVKWFKGDLELRPST 746
Query: 382 FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVM 441
F P LG + + Q + + V G A
Sbjct: 747 FLIIDPLLGLLKI-----------------------QETQDLDAGDYTCVAINEAGRATG 783
Query: 442 EVA------PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWL-LNGQPIQYARSTCEA 494
++ P F D ++ G + L C V+G P P I W L+ PI ++R +
Sbjct: 784 KITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPI-FSRPFSVS 842
Query: 495 GVAELH-----IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
+++L I + D GTY C AEN G++ VTV +
Sbjct: 843 SISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV-----------------T 885
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQV-SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQ 608
AP+ S V++G Q+T+ + +GNP PE W+ N + ++ G+
Sbjct: 886 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSL 945
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 668
H I+ V +D G YTC A N AG + V P + ++ G
Sbjct: 946 H---IERVQLQDGGEYTCVASNVAGTNNKTTSVVVH-----VLPTIQHGQQILSTIEGIP 997
Query: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPW--HAGQYEIL 726
V + C +G+P P+V W + G+ + + F + ++ V P +G+Y
Sbjct: 998 VTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYV-----VSPGGEESGEYVCT 1052
Query: 727 LKNRVGECSCQVSL 740
N G +V L
Sbjct: 1053 ATNTAGYAKRKVQL 1066
Score = 85.5 bits (210), Expect = 4e-16
Identities = 79/296 (26%), Positives = 113/296 (38%), Gaps = 28/296 (9%)
Query: 441 MEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQY-ARSTCEAGVAEL 499
+ V P K V GQ + C+ +GTP+P ITW G + L
Sbjct: 1167 VHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTL 1226
Query: 500 HIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQG 559
I A P D G YTC+A N G + V E + E P F +
Sbjct: 1227 SIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLE--------PPYNTTFQER 1278
Query: 560 LSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESE-DFHFEQRGTQHSLCIQEVFP 618
+++ ++ G P P + WLHNG E+ E + GT L I V P
Sbjct: 1279 VAN------QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT--LLVIASVTP 1330
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPR--SVTASLGQSVLISCAIA 676
D G Y C A N AG + L V P P K + +V+ L Q + C +
Sbjct: 1331 YDNGEYICVAVNEAGTTERKYNLKVHVP-----PVIKDKEQVTNVSVLLNQLTNLFCEVE 1385
Query: 677 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
G P P + W +D + ++ + + N + L L + P AG+Y N G
Sbjct: 1386 GTPSPIIMWYKDNVQV-TESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAG 1438
Score = 79.7 bits (195), Expect = 2e-14
Identities = 57/223 (25%), Positives = 91/223 (40%), Gaps = 25/223 (11%)
Query: 459 GQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAEN 518
G + +L C V+G P P I W G I+ + + G L I + ED G YTC+A N
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATN 4423
Query: 519 ALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVS 578
G V S +T+ P+ +P + + G ++ + Q +
Sbjct: 4424 EAGVVERSMSLTLQSP----------PIITLEPVETV---------INAGGKIILNCQAT 4464
Query: 579 GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQ 638
G P P + W G+ I + + + +SL I + EDT + C A N G V +
Sbjct: 4465 GEPQPTITWSRQGHSISWDDRVNVL---SNNSLYIADAQKEDTSEFECVARNLMGSVLVR 4521
Query: 639 AVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFP 681
+ VQ H G W S R+ + + G+ + + P P
Sbjct: 4522 VPVIVQ-VHGGFSQW--SAWRACSVTCGKGIQKRSRLCNQPLP 4561
Score = 72.4 bits (176), Expect = 4e-12
Identities = 63/242 (26%), Positives = 95/242 (39%), Gaps = 49/242 (20%)
Query: 1033 QKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKAL 1092
+ L V+V EG + L+C+ ++ PP I W NG+ + + + + +G + + I+KA
Sbjct: 3064 ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQM--LHIKKAE 3121
Query: 1093 PEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDAT 1152
D G Y C A N AG+ DD N P P + G E +
Sbjct: 3122 VSDTGQYVCRAINVAGR---------DDKNFHLNVYVP-----------PSIEGPEREVI 3161
Query: 1153 VKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQES 1212
V+ P V L TG P T W+K K+I+ S
Sbjct: 3162 VETISNP--------------------------VTLTCDATGIPPPTIAWLKNHKRIENS 3195
Query: 1213 EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCAS 1272
+ ++V GSKL I ++ G YT + N G Q L+ + P AG S
Sbjct: 3196 DSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLS-IQVPPSVAGAEIPS 3254
Query: 1273 DI 1274
D+
Sbjct: 3255 DV 3256
Score = 72.0 bits (175), Expect = 5e-12
Identities = 57/212 (26%), Positives = 84/212 (39%), Gaps = 37/212 (17%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P N+ + E + G P P +TW ++G P++ + G R L +
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGR---MLRLMQTTM 2449
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
ED G+YTC N +G + L+V P I GE
Sbjct: 2450 EDAGQYTCVVRNAAGEERKIFGLSVL--------------------------VPPHIVGE 2483
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
L V VKE Q +C++TG P P++TW K PLQ + +G + L
Sbjct: 2484 ------NTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII--SGGRFL 2535
Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+I V G YTCL + +G S S L++
Sbjct: 2536 QITNVQVPHTGRYTCLASSPAGHKSRSFSLNV 2567
Score = 71.6 bits (174), Expect = 6e-12
Identities = 58/213 (27%), Positives = 88/213 (41%), Gaps = 38/213 (17%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQP-ITSGGRFLLDCGIRGTFSLVIHAVH 97
P + + G + E V+G P P VTW ++G P I + G +LD G L + +H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG----HILQLKNIH 2354
Query: 98 EEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWG 157
D G+Y C A N +G +L+V AP PSI G
Sbjct: 2355 VSDTGRYVCVAVNVAGMTDKKYDLSVH---------------------AP-----PSIIG 2388
Query: 158 ECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV 217
+ V E +C+ +G P P +TW K P+ S V + +G ++
Sbjct: 2389 N-----HRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI--LSGGRM 2441
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L + +D G YTC+V N +G+ LS+
Sbjct: 2442 LRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV 2474
Score = 70.9 bits (172), Expect = 1e-11
Identities = 53/200 (26%), Positives = 77/200 (38%), Gaps = 38/200 (19%)
Query: 51 KFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
+ E RG P P +TW ++G P++S L + G L + + D G+YTC A N
Sbjct: 2030 RLECEARGIPAPSLTWLKDGSPVSSFSNGLQ--VLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 111 GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
+G +Q ++L V PP + V
Sbjct: 2088 AAGEKQRDIDLRV----------------------------------YVPPNIMGEEQNV 2113
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
V Q C+ P P +TWLK PL +S+SE VL+I D G
Sbjct: 2114 SVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENR--SVLKIEDAQVQDTGR 2171
Query: 231 YTCLVVNGSGKASMSAELSI 250
YTC N +GK + ++I
Sbjct: 2172 YTCEATNVAGKTEKNYNVNI 2191
Score = 70.1 bits (170), Expect = 2e-11
Identities = 59/251 (23%), Positives = 98/251 (39%), Gaps = 46/251 (18%)
Query: 27 MPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIR 86
+ + E P + P+N G+ GYP+P++ W N I R+ +
Sbjct: 606 LTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSD-- 663
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGA-RQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
GT L I +D G Y C A+N +G +Q + +E
Sbjct: 664 GT--LFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEA-------------------- 701
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
PK ++V G + CK +G P PQV W KG++ L+PS
Sbjct: 702 ---------------PKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPST 746
Query: 206 RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK 265
+ + G+ L+I D G YTC+ +N +G+A+ L + + F++E
Sbjct: 747 FLIIDPLLGL--LKIQETQDLDAGDYTCVAINEAGRATGKITLDV----GSPPVFIQEPA 800
Query: 266 ATNSDVRKEVT 276
+ ++ VT
Sbjct: 801 DVSMEIGSNVT 811
Score = 70.1 bits (170), Expect = 2e-11
Identities = 58/201 (28%), Positives = 86/201 (42%), Gaps = 38/201 (18%)
Query: 51 KFEGRVRGYPEPQVTWHRNGQPITSGGRFL-LDCGIRGTFSLVIHAVHEEDRGKYTCEAT 109
K E RG P P +TW+++GQPI S + L +D +G + L I D YTC
Sbjct: 1566 KLECETRGLPMPAITWYKDGQPIMSSSQALYID---KGQY-LHIPRAQVSDSATYTCHVA 1621
Query: 110 NGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGR 169
N +G T E SF + P P I G AT L +
Sbjct: 1622 NVAG--------TAEKSFHVDVYVP------------------PMIEGN----LATPLNK 1651
Query: 170 VVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVG 229
VV + CK G P P +TWLK VP++ + + + + G + LEI + D G
Sbjct: 1652 QVVIAHSL-TLECKAAGNPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRG 1708
Query: 230 VYTCLVVNGSGKASMSAELSI 250
Y C+ + +G+ + E+ +
Sbjct: 1709 QYICVATSVAGEKEIKYEVDV 1729
Score = 65.9 bits (159), Expect = 3e-10
Identities = 58/223 (26%), Positives = 86/223 (38%), Gaps = 37/223 (16%)
Query: 33 PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHR-NGQPITSGGRFLLDCGIRGTFSL 91
P FI P ++ ++ G+ V+GYPEP + W R + PI S + T +L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVET 151
I + D+G Y CEA N G Q +TV G AP +
Sbjct: 853 FILNLWASDKGTYICEAENQFGKIQSETTVTVTG------------------LVAPLIGI 894
Query: 152 RPSIWGECPPKFATKLGRVVVKEGQMGRFSCKI-TGRPQPQVTWLKGNVPLQPSARVSVS 210
PS+ V EGQ C + G P P+ W+K + L + ++V
Sbjct: 895 SPSVAN--------------VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVR 940
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
L I V D G YTC+ N +G + + + + L
Sbjct: 941 SDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL 980
Score = 63.5 bits (153), Expect = 2e-09
Identities = 56/237 (23%), Positives = 89/237 (37%), Gaps = 40/237 (16%)
Query: 33 PAFILPPR--NLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFS 90
P ++ P+ NL + V G+P P ++W +N QPI L+ + G +
Sbjct: 2963 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGGRT 3019
Query: 91 LVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVE 150
L I D G+YTC A N +G + LTV + P+++
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTV--------------------YVPPSIK 3059
Query: 151 TRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVS 210
S L V V+EG C+ P P +TW K + S V +
Sbjct: 3060 DHDS----------ESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEIL 3109
Query: 211 EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI---QGLDSANRSFVRET 264
Q+L I D G Y C +N +G+ + L++ ++ R + ET
Sbjct: 3110 ADG--QMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVET 3164
Score = 63.2 bits (152), Expect = 2e-09
Identities = 73/322 (22%), Positives = 118/322 (36%), Gaps = 63/322 (19%)
Query: 1005 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1064
+ C + T+N+ S P + Q + EG + L C+ S +P ++IW+
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSK 1016
Query: 1065 NGKTLKTTKF-IILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTV----- 1118
G+ + T+ +GSL VS E+ G Y C A N AG A+ Q+TV
Sbjct: 1017 KGELISTSSAKFSAGADGSLYVVS---PGGEESGEYVCTATNTAGYAKRKVQLTVYVRPR 1073
Query: 1119 ---------DDAPASENTKAPEMKSR--RPKSSLPPVLGTESDATVKKKPAPKTP--PKA 1165
D P + A E + KS PP++ + + +P+ P
Sbjct: 1074 VFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG 1133
Query: 1166 AM----------------------------------PPQIIQFPEDQKVRAGESVELFGK 1191
+M PP+I + P+ KV+ G+ V++
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCN 1193
Query: 1192 VTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQ 1251
GT TW K + V N + L+I A G YT + N G+ +
Sbjct: 1194 AQGTPLPVITWSKGGSTMLVDGEHHVSNPD--GTLSIDQATPSDAGIYTCVATNIAGTDE 1251
Query: 1252 AQVNLTVVDKP-----DPPAGT 1268
++ L V + P +PP T
Sbjct: 1252 TEITLHVQEPPTVEDLEPPYNT 1273
Score = 63.2 bits (152), Expect = 2e-09
Identities = 52/207 (25%), Positives = 84/207 (40%), Gaps = 35/207 (16%)
Query: 46 EGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
EG + G P+P V W + G+ I TS +F G G SL + + E+ G+Y
Sbjct: 994 EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKF--SAGADG--SLYVVSPGGEESGEY 1049
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
C ATN +G + V+LTV RP ++G+
Sbjct: 1050 VCTATNTAGYAKRKVQLTVY--------------------------VRPRVFGDQRGLSQ 1083
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQP-SARVSVSEKNGMQVLEIHGV 223
K + V G+ C++ P P +TW K + P S R + M++ E
Sbjct: 1084 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITE---T 1140
Query: 224 NQDDVGVYTCLVVNGSGKASMSAELSI 250
D G+Y C+ N +G + + +L++
Sbjct: 1141 RTSDSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 63.2 bits (152), Expect = 2e-09
Identities = 50/211 (23%), Positives = 82/211 (38%), Gaps = 38/211 (18%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPIT--SGGRFLLDCGIRGTFSLVIHAVHEE 99
L + EG G P P + W + G P+ S GR + G R L I +
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR---QLQISIAEKS 2262
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC 159
D Y+C A+N +G + L V + T+ + S P
Sbjct: 2263 DAALYSCVASNVAGTAKKEYNLQV-----------YIRPTITNSGSHPT----------- 2300
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
++V G+ C++ G P P VTW+K PL + V + ++ +L+
Sbjct: 2301 ---------EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEG--HILQ 2349
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
+ ++ D G Y C+ VN +G +LS+
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV 2380
Score = 62.0 bits (149), Expect = 5e-09
Identities = 50/215 (23%), Positives = 79/215 (36%), Gaps = 41/215 (19%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSG-GRF-LLDCGIRGTFSLVIHAV 96
P++L I + E G P P++TW ++G + R+ +L+ G L I +
Sbjct: 3719 PQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENGF-----LHIQSA 3773
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
H D G+Y C ATN +G + ++L V
Sbjct: 3774 HVTDTGRYLCMATNAAGTDRRRIDLQV--------------------------------- 3800
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
PP A + V +C+ TG P+P + W K L +
Sbjct: 3801 -HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSG 3859
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
L I + DD Y C V NG+G + +L++Q
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 60.1 bits (144), Expect = 2e-08
Identities = 62/258 (24%), Positives = 91/258 (35%), Gaps = 57/258 (22%)
Query: 7 VASSHISKT---------SLSVDPSRVDSMPLTEAPAFILP-PRNLCIKEGATAKFEGRV 56
+ S+H++ T + D R+D P I P P N+ +
Sbjct: 3770 IQSAHVTDTGRYLCMATNAAGTDRRRIDLQ--VHVPPSIAPGPTNMTVIVNVQTTLACEA 3827
Query: 57 RGYPEPQVTWHRNGQPIT----SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
G P+P + W +NG + LL G SLVI + +D Y C TNG+
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSG-----SLVIISPSVDDTATYECTVTNGA 3882
Query: 113 GARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVV 172
G + TV+LT V+ PSI E TK V+
Sbjct: 3883 GDDKRTVDLT--------------------------VQVPPSIADEPTDFLVTKHAPAVI 3916
Query: 173 KEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYT 232
+C +G P P + W K + L P +G +EI + G YT
Sbjct: 3917 --------TCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSG--AIEILATQLNHAGRYT 3966
Query: 233 CLVVNGSGKASMSAELSI 250
C+ N +G A L +
Sbjct: 3967 CVARNAAGSAHRHVTLHV 3984
Score = 59.7 bits (143), Expect = 2e-08
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 38/296 (12%)
Query: 446 SFSSVLKDCAVIEGQD----FVLQ-----CSVRGTPVPRITWLLNGQPIQYARSTCEAGV 496
SFSS++ D + + + LQ CSV ++++ NG + + E+
Sbjct: 422 SFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQYLKESAS 481
Query: 497 AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIF 556
L I D G Y C+A ++ G + V E P
Sbjct: 482 VNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP-------------------PPV 522
Query: 557 LQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEV 616
+Q +++ V G + +T + + W N +++ +E SL ++ V
Sbjct: 523 IQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLELKSV 581
Query: 617 FPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIA 676
D G Y C + G LTVQEP P P++ + + G V I C+
Sbjct: 582 KFNDAGEYHCMVSSEGGSSAASVFLTVQEP-----PKVTVMPKNQSFTGGSEVSIMCSAT 636
Query: 677 GDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVG 732
G P P + W + + G D TL +K P AG Y L N G
Sbjct: 637 GYPKPKIAWTVNDMFI---VGSHRYRMTSD-GTLFIKNAAPKDAGIYGCLASNSAG 688
Score = 59.3 bits (142), Expect = 3e-08
Identities = 52/215 (24%), Positives = 73/215 (33%), Gaps = 45/215 (20%)
Query: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1107
L C + PP TI W N K ++ + + + + I ++ D G Y C+A N
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230
Query: 1108 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAM 1167
G+A+ +++ P+ V G E
Sbjct: 3231 GKAQKYYFLSIQVPPS--------------------VAGAE------------------- 3251
Query: 1168 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1227
P D V GE+VEL G W+K K I E ++ S NGS L
Sbjct: 3252 ------IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLN 3305
Query: 1228 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
I A G YT + N G NL V P
Sbjct: 3306 IYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP 3340
Score = 58.9 bits (141), Expect = 4e-08
Identities = 65/241 (26%), Positives = 91/241 (37%), Gaps = 65/241 (26%)
Query: 7 VASSHISKTSLSVD-PSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVT 65
VA S + T L+V P R+ S TE + + E + A G P P +
Sbjct: 4153 VAGSSSTSTKLTVHVPPRIRS---TEG--------HYTVNENSQAILPCVADGIPTPAIN 4201
Query: 66 WHRNGQPITSGGRFLLDCGIRGTFS------LVIHAVHEEDRGKYTCEATNGSGARQVTV 119
W ++ +L + G ++ L++ V ED G YTC A N +G TV
Sbjct: 4202 WKKDN---------VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Query: 120 ELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGR 179
LTV P F G V + +G+ R
Sbjct: 4253 SLTV----------------------------------HVLPTFTELPGDVSLNKGEQLR 4278
Query: 180 FSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS 239
SCK TG P P++TW N + P+ SV NG L I V+++D G Y C N
Sbjct: 4279 LSCKATGIPLPKLTWTFNN-NIIPAHFDSV---NGHSELVIERVSKEDSGTYVCTAENSV 4334
Query: 240 G 240
G
Sbjct: 4335 G 4335
Score = 58.5 bits (140), Expect = 6e-08
Identities = 57/222 (25%), Positives = 91/222 (40%), Gaps = 41/222 (18%)
Query: 56 VRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGAR 115
V G P P + W ++GQ I F + R LVI + G Y C A N +G
Sbjct: 1758 VTGSPPPTIMWLKDGQLIDERDGFKILLNGR---KLVIAQAQVSNTGLYRCMAANTAGDH 1814
Query: 116 QVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEG 175
+ E+TV P+I K + RVVVK
Sbjct: 1815 KKEFEVTVH--------------------------VPPTI------KSSGLSERVVVKYK 1842
Query: 176 QMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLV 235
+ C G P P +TWLK + P+ +A+ ++ ++ +VL+I +D G YTC+
Sbjct: 1843 PVA-LQCIANGIPNPSITWLKDDQPVN-TAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVA 1900
Query: 236 VNGSGKASMSAELSIQ---GLDSANRSFVRETKATNSDVRKE 274
N +G+ +L + L+ A + + ET ++ V+ E
Sbjct: 1901 TNAAGETQQHIQLHVHEPPSLEDAGK-MLNETVLVSNPVQLE 1941
Score = 58.2 bits (139), Expect = 7e-08
Identities = 46/218 (21%), Positives = 83/218 (38%), Gaps = 49/218 (22%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
P N + + E + G P P +TW ++G P+ + ++ G + L I + E
Sbjct: 1648 PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK---KLEIMSAQE 1704
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
DRG+Y C AT+ +G +++ E+ D PA+E
Sbjct: 1705 IDRGQYICVATSVAGEKEIKYEV--------------------DVLVPPAIEG------- 1737
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQV- 217
+ +V + C +TG P P + WLK + E++G ++
Sbjct: 1738 -----GDETSYFIVMVNNLLELDCHVTGSPPPTIMWLKDG--------QLIDERDGFKIL 1784
Query: 218 -----LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L I + G+Y C+ N +G E+++
Sbjct: 1785 LNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 55.8 bits (133), Expect = 4e-07
Identities = 50/200 (25%), Positives = 80/200 (40%), Gaps = 38/200 (19%)
Query: 51 KFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN 110
+ E + G P P +TW+++ + + SG + RG + I + D G Y C A N
Sbjct: 1939 QLECKAAGNPVPVITWYKDNR-LLSGSTSMTFLN-RGQI-IDIESAQISDAGIYKCVAIN 1995
Query: 111 GSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRV 170
+GA ++ F + V PSI G + + V
Sbjct: 1996 SAGATEL--------------------------FYSLQVHVAPSISG------SNNMVAV 2023
Query: 171 VVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGV 230
VV R C+ G P P +TWLK P+ S + +G ++L + D G
Sbjct: 2024 VVNNPV--RLECEARGIPAPSLTWLKDGSPVS-SFSNGLQVLSGGRILALTSAQISDTGR 2080
Query: 231 YTCLVVNGSGKASMSAELSI 250
YTC+ VN +G+ +L +
Sbjct: 2081 YTCVAVNAAGEKQRDIDLRV 2100
Score = 55.8 bits (133), Expect = 4e-07
Identities = 52/226 (23%), Positives = 85/226 (37%), Gaps = 48/226 (21%)
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
++ V GK + L+C+V PP T+ W +G L K + + EG + + ++ D
Sbjct: 2301 EIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHI--LQLKNIHVSDT 2358
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1156
G Y CVA N AG + ++V AP P ++G
Sbjct: 2359 GRYVCVAVNVAGMTDKKYDLSV-HAP-------------------PSIIGNH-------- 2390
Query: 1157 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
+ PE+ V SV L + +G + TW K + S ++
Sbjct: 2391 ----------------RSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVR 2434
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ G L ++ E G YT +V N G + L+V+ P
Sbjct: 2435 I--LSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPP 2478
Score = 55.5 bits (132), Expect = 5e-07
Identities = 60/275 (21%), Positives = 100/275 (36%), Gaps = 49/275 (17%)
Query: 1034 KLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALP 1093
K+ + V + L+C+ + +P I W + + L + + G + + IE A
Sbjct: 1926 KMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQI--IDIESAQI 1983
Query: 1094 EDRGLYKCVAKNDAGQAECSCQVTVDDAPA---------------------SENTKAPE- 1131
D G+YKCVA N AG E + V AP+ + AP
Sbjct: 1984 SDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSL 2043
Query: 1132 --MKSRRPKSSLPPVLGTESDATVKKKPAPKTPP---------------------KAAMP 1168
+K P SS L S + + + + +P
Sbjct: 2044 TWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103
Query: 1169 PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTI 1228
P I+ ++ V ++VEL + P T TW+K + + + + SEN S L I
Sbjct: 2104 PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI--SENRSVLKI 2161
Query: 1229 LAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1263
A+ + G YT N G + N+ + P+
Sbjct: 2162 EDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPN 2196
Score = 55.5 bits (132), Expect = 5e-07
Identities = 52/212 (24%), Positives = 82/212 (38%), Gaps = 49/212 (23%)
Query: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1107
L C+ ++ PP T+ W +G L ++ +++ G + + I +A ED G Y CVA N+A
Sbjct: 2797 LYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQIPRAKVEDAGRYTCVAVNEA 2854
Query: 1108 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL-GTESDATVKKKPAPKTPPKAA 1166
G+ V V +PP++ G SD
Sbjct: 2855 GEDSLQYDVRV---------------------LVPPIIKGANSD---------------- 2877
Query: 1167 MPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKL 1226
PE+ V +S + +G+ +W K + + E +H K NG L
Sbjct: 2878 -------LPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKF--LSNGRIL 2928
Query: 1227 TILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
IL + G Y + EN GS + NL V
Sbjct: 2929 QILNTQITDIGRYVCVAENTAGSAKKYFNLNV 2960
Score = 55.1 bits (131), Expect = 6e-07
Identities = 53/213 (24%), Positives = 79/213 (37%), Gaps = 49/213 (23%)
Query: 1046 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
L L+C+ + +P + W +G +K I + G + I A DRG Y CVA +
Sbjct: 1659 LTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYICVATS 1716
Query: 1106 DAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKA 1165
AG+ E +V V PA E G E+ +
Sbjct: 1717 VAGEKEIKYEVDVLVPPAIEG-------------------GDETSYFI------------ 1745
Query: 1166 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1225
V +EL VTG+ P T W+K + I E + K+ NG K
Sbjct: 1746 --------------VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKI--LLNGRK 1789
Query: 1226 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
L I A+ + G Y + N G + + +TV
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV 1822
Score = 54.3 bits (129), Expect = 1e-06
Identities = 51/227 (22%), Positives = 88/227 (38%), Gaps = 39/227 (17%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
++V + L L+C+ + P A++ W +G+ LK+ + ++ G ++ I++A D
Sbjct: 2682 KEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGH--TLQIKEAQISD 2739
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G Y CVA N AG+ E V + P+ + + +L T +
Sbjct: 2740 TGRYTCVASNIAGEDELDFDVNIQVPPSFQKL-----------WEIGNMLDTGRNG---- 2784
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
E + V + L+ + P T TW K + S+
Sbjct: 2785 --------------------EAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSD-- 2822
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
KV G L I A+ E G YT + N+ G Q ++ V+ P
Sbjct: 2823 KVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPP 2869
Score = 53.5 bits (127), Expect = 2e-06
Identities = 47/194 (24%), Positives = 71/194 (36%), Gaps = 42/194 (21%)
Query: 58 GYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQV 117
G P P+ W +N + +R SL I V +D G+YTC A+N +G
Sbjct: 916 GNPIPERRWIKNSAMLLQNPYIT----VRSDGSLHIERVQLQDGGEYTCVASNVAGTNNK 971
Query: 118 TVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQM 177
T + V Q GQ ++S G + P
Sbjct: 972 TTSVVVHVLPTIQHGQQILSTIEGIPVTLP------------------------------ 1001
Query: 178 GRFSCKITGRPQPQVTW-LKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVV 236
CK +G P+P V W KG + SA+ S + V+ G ++ G Y C
Sbjct: 1002 ----CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTAT 1054
Query: 237 NGSGKASMSAELSI 250
N +G A +L++
Sbjct: 1055 NTAGYAKRKVQLTV 1068
Score = 53.5 bits (127), Expect = 2e-06
Identities = 81/391 (20%), Positives = 145/391 (37%), Gaps = 68/391 (17%)
Query: 960 AKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKRGHAGTTDNE 1019
AK + + P P T P G+ K E S S L C + +
Sbjct: 1114 AKETQLISPFS---PRHTFLPSGSMKITETRTSDSGMYL---------CVATNIAGNVTQ 1161
Query: 1020 KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT-KFIILS 1078
+ P ++ + + V G+++ + C P I W+ G T+ + + +
Sbjct: 1162 AVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSN 1221
Query: 1079 QEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPK 1138
+G+L SI++A P D G+Y CVA N AG E + V + P E+ + P
Sbjct: 1222 PDGTL---SIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPP-------- 1270
Query: 1139 SSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPI 1198
+ T +++ A Q I+FP K GT
Sbjct: 1271 ----------YNTTFQERVA----------NQRIEFPCPAK--------------GTPKP 1296
Query: 1199 TCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
T W+ +++ E + E+G+ L I + G Y + N+ G+ + + NL
Sbjct: 1297 TIKWLHNGRELTGRE-PGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNL-- 1353
Query: 1259 VDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRST 1318
K P + + S+ L+ + + S I +W N E +T ++
Sbjct: 1354 --KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPS-PIIMWYKDNVQVTESSTIQTV 1410
Query: 1319 S----FNVQDLLPDHEYKFRVRAINVYGTSE 1345
+ + P+ ++ +AIN+ GTS+
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAGTSQ 1441
Score = 52.4 bits (124), Expect = 4e-06
Identities = 58/250 (23%), Positives = 95/250 (38%), Gaps = 52/250 (20%)
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT--TKFIILSQEGSLCSVSIEKALPE 1094
DV V G+ + L C + P I W +GK + + T+ I +S GS +++I AL
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS--TLNIYGALTS 3312
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
D G Y CVA N AG+ + + V P + G + +A
Sbjct: 3313 DTGKYTCVATNPAGEEDRIFNLNV--------------------YVTPTIRGNKDEA--- 3349
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
E S+ + + TGT P W+K + S H
Sbjct: 3350 ---------------------EKLMTLVDTSINIECRATGTPPPQINWLKNGLPLPLSSH 3388
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP--DPPAGTPCAS 1272
+++ + G + I+ A+ YT + N+ G NL V P D GT +
Sbjct: 3389 IRLLAA--GQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEIT 3446
Query: 1273 DIRSSSLTLS 1282
++ SS +++
Sbjct: 3447 VLKGSSTSMA 3456
Score = 51.6 bits (122), Expect = 7e-06
Identities = 50/227 (22%), Positives = 89/227 (39%), Gaps = 43/227 (18%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
+DV V L C+ S PPATI W +G L++ + I + G ++ I A ++
Sbjct: 2583 EDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGR--TLQILNAQEDN 2640
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G Y CVA N+AG+ +K K +PP++ + D
Sbjct: 2641 AGRYSCVATNEAGEM---------------------IKHYEVKVYIPPII-NKGDLW--- 2675
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
P PK + K++ ++ L + + +W K + ++ +H+
Sbjct: 2676 --GPGLSPK------------EVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDHV 2721
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ + NG L I A+ G YT + N G + ++ + P
Sbjct: 2722 NI--AANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Score = 51.6 bits (122), Expect = 7e-06
Identities = 55/213 (25%), Positives = 78/213 (36%), Gaps = 41/213 (19%)
Query: 39 PRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE 98
PR++ + E + P P +TW RNG+ + + R + + G L I+
Sbjct: 3628 PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRI---LSGGRYLQINNADL 3684
Query: 99 EDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D YTC A+N +G LT V P+I G
Sbjct: 3685 GDTANYTCVASNIAGKTTREFILT--------------------------VNVPPNIKGG 3718
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLK-GNVPLQPSARVSVSEKNGMQV 217
P L + V E C G P P++TW K G V AR S+ E NG
Sbjct: 3719 -PQSLVILLNKSTVLE-------CIAEGVPTPRITWRKDGAVLAGNHARYSILE-NGF-- 3767
Query: 218 LEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
L I + D G Y C+ N +G +L +
Sbjct: 3768 LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQV 3800
Score = 51.6 bits (122), Expect = 7e-06
Identities = 55/232 (23%), Positives = 79/232 (34%), Gaps = 56/232 (24%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTT--KFIILSQEGSLCSV 1086
P + + ++HV +LL C+ + P I W G + T+ +L G +
Sbjct: 3988 PVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG----L 4043
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLG 1146
I +A+ ED G Y CVA+N AG A ++ V P +P +K P L
Sbjct: 4044 QISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPPVI----SPHLKEYVIAVDKPITLS 4099
Query: 1147 TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFR 1206
E+D G P TW K
Sbjct: 4100 CEAD-------------------------------------------GLPPPDITWHKDG 4116
Query: 1207 KQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ I ES +V +S L I + G YT + N GS LTV
Sbjct: 4117 RAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 51.6 bits (122), Expect = 7e-06
Identities = 62/279 (22%), Positives = 99/279 (35%), Gaps = 54/279 (19%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P L++ +A K + L C+ PP I W +G+ + + + GSL +
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFV 4138
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLP------ 1142
+ P D G Y C+A N AG + S ++TV P +T+ + ++ LP
Sbjct: 4139 Q---PGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGI 4195
Query: 1143 --PVLGTESD--------------------------------ATVKKKPAPKTPPKAAMP 1168
P + + D V A + ++
Sbjct: 4196 PTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT 4255
Query: 1169 ----PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENG- 1223
P + P D + GE + L K TG TW F I + +S NG
Sbjct: 4256 VHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW-TFNNNIIPAHF----DSVNGH 4310
Query: 1224 SKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
S+L I +E G Y EN +G +A + V +P
Sbjct: 4311 SELVIERVSKEDSGTYVCTAENSVGFVKA-IGFVYVKEP 4348
Score = 50.8 bits (120), Expect = 1e-05
Identities = 63/278 (22%), Positives = 97/278 (34%), Gaps = 53/278 (19%)
Query: 1008 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1067
C ++ TD + + AP ++ VA G +++C+ S PP + W
Sbjct: 681 CLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDL 740
Query: 1068 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1127
L+ + F+I+ + L + I++ D G Y CVA N+AG+A + ++T+D
Sbjct: 741 ELRPSTFLII--DPLLGLLKIQETQDLDAGDYTCVAINEAGRA--TGKITLD-------- 788
Query: 1128 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1187
PP IQ P D + G +V
Sbjct: 789 -------------------------------------VGSPPVFIQEPADVSMEIGSNVT 811
Query: 1188 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSE--NGSKLTILAARQEHCGCYTLLVEN 1245
L V G T W + S V + L IL G Y EN
Sbjct: 812 LPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAEN 871
Query: 1246 KLGSRQAQVNLTVVDKPDPPAG--TPCASDIRSSSLTL 1281
+ G Q++ +TV P G A+ I LTL
Sbjct: 872 QFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTL 909
Score = 49.7 bits (117), Expect = 3e-05
Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 9/135 (6%)
Query: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
+L I +V D G Y C A +SAG R Q V EP P I P +VT + G+
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEP-----PPVIQVPNNVTVTPGERA 537
Query: 670 LISCAIAGDPFPTVHWLR-DGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 728
+++C I + W R D + L N +L LK V+ AG+Y ++
Sbjct: 538 VLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLAN---LSLELKSVKFNDAGEYHCMVS 594
Query: 729 NRVGECSCQVSLMLQ 743
+ G + V L +Q
Sbjct: 595 SEGGSSAASVFLTVQ 609
Score = 49.7 bits (117), Expect = 3e-05
Identities = 51/218 (23%), Positives = 78/218 (35%), Gaps = 51/218 (23%)
Query: 1046 LLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKN 1105
L L C V+ PP TI+W +G+ + + G + I +A + GLY+C+A N
Sbjct: 1752 LELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGR--KLVIAQAQVSNTGLYRCMAAN 1809
Query: 1106 DAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKA 1165
AG + +VTV P +++ G VK KP
Sbjct: 1810 TAGDHKKEFEVTVHVPPTIKSS------------------GLSERVVVKYKPVALQCIAN 1851
Query: 1166 AMP-PQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS 1224
+P P I +DQ V + ++K+++S G
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQG----------------------------NLKIQSS--GR 1881
Query: 1225 KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
L I E G YT + N G Q + L V + P
Sbjct: 1882 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPP 1919
Score = 49.7 bits (117), Expect = 3e-05
Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 3/107 (2%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
P +K + S+++ + V EG++ +C+ P P + W+K+ + I ES H +I D
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQ-- 3113
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1791
L I D +Y C+A+N G L V EG E
Sbjct: 3114 -MLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPERE 3159
Score = 49.7 bits (117), Expect = 3e-05
Identities = 51/216 (23%), Positives = 80/216 (37%), Gaps = 53/216 (24%)
Query: 1043 GKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCV 1102
G +L C+V DP TI W G ++ + I GSL +I + ED G Y CV
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSL---AIYGTVNEDAGDYTCV 4420
Query: 1103 AKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTP 1162
A N+AG E S +T+ PP++ E
Sbjct: 4421 ATNEAGVVERSMSLTLQS---------------------PPIITLE-------------- 4445
Query: 1163 PKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSEN 1222
P + + AG + L + TG T TW + I + + V ++
Sbjct: 4446 ------------PVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSN-- 4491
Query: 1223 GSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ L I A++E + + N +GS +V + V
Sbjct: 4492 -NSLYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 49.3 bits (116), Expect = 3e-05
Identities = 46/215 (21%), Positives = 77/215 (35%), Gaps = 51/215 (23%)
Query: 1048 LQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDA 1107
+ C V S P T+ + NG TL +++ +E + ++ I K D G Y+C+A + A
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYL---KESASVNLDIAKVTLSDEGFYECIAVSSA 505
Query: 1108 GQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAM 1167
G V +
Sbjct: 506 GTGRAQTFFDVSE----------------------------------------------- 518
Query: 1168 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1227
PP +IQ P + V GE L + TW + + ++ +E ++ N S L
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS-LE 577
Query: 1228 ILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ + + G Y +V ++ GS A V LTV + P
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP 612
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/229 (22%), Positives = 82/229 (35%), Gaps = 53/229 (23%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
+++ V E + L C+ S P +I W +G + + + + G + + + + ED
Sbjct: 2394 ENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRM--LRLMQTTMED 2451
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G Y CV +N AG+ ++V
Sbjct: 2452 AGQYTCVVRNAAGEERKIFGLSV------------------------------------- 2474
Query: 1156 KPAPKTPPKAAMPPQII--QFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1213
+PP I+ ED KV+ +SV L +VTG TW K + +QE E
Sbjct: 2475 ----------LVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDE 2524
Query: 1214 HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ G L I + H G YT L + G + +L V P
Sbjct: 2525 AHHI--ISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSP 2571
Score = 47.8 bits (112), Expect = 1e-04
Identities = 27/84 (32%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
HV P F++ D+ + +G R CK G P P++ W ++ I HF +G+
Sbjct: 4257 HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII--PAHFD---SVNGHS 4311
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLG 1769
L+I V +D Y C A NS+G
Sbjct: 4312 ELVIERVSKEDSGTYVCTAENSVG 4335
Score = 47.4 bits (111), Expect = 1e-04
Identities = 46/214 (21%), Positives = 78/214 (36%), Gaps = 46/214 (21%)
Query: 1035 LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE 1094
L+DV V E + + L C+V+ +P I W +G+ L+ + + G + I
Sbjct: 2486 LEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRF--LQITNVQVP 2543
Query: 1095 DRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVK 1154
G Y C+A + AG S + V +P + G SD
Sbjct: 2544 HTGRYTCLASSPAGHKSRSFSLNVFVSPT--------------------IAGVGSDGN-- 2581
Query: 1155 KKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEH 1214
PED V L + P T TW K ++ + +
Sbjct: 2582 --------------------PEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRN 2621
Query: 1215 MKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248
+++ G L IL A++++ G Y+ + N+ G
Sbjct: 2622 IRI--LPGGRTLQILNAQEDNAGRYSCVATNEAG 2653
Score = 47.0 bits (110), Expect = 2e-04
Identities = 58/249 (23%), Positives = 93/249 (37%), Gaps = 53/249 (21%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
+++ V +G + C P ++ W +G+ L + +S G + + + KA ED
Sbjct: 3443 EEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMV--LQLLKAETED 3500
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G Y C+A N+AG E +K +K P P + G+E
Sbjct: 3501 SGKYTCIASNEAG----------------EVSKHFILKVLEP----PHINGSEEH----- 3535
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
E+ V +EL +G TWMK + + +++
Sbjct: 3536 --------------------EEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTD-- 3573
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDI- 1274
+V+ G L I A+ E G YT L + G + L V P AGT DI
Sbjct: 3574 QVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEY-LVRVHVPPNIAGTDEPRDIT 3632
Query: 1275 --RSSSLTL 1281
R+ +TL
Sbjct: 3633 VLRNRQVTL 3641
Score = 46.6 bits (109), Expect = 2e-04
Identities = 27/94 (28%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
HV P + L +EG CK G P P V+W K + I S + +
Sbjct: 978 HVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS---SAKFSAGADG 1034
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
SL + G++ +Y C A N+ G A +L V
Sbjct: 1035 SLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTV 1068
Score = 46.6 bits (109), Expect = 2e-04
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 3/97 (3%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
HV P T V E S A C +G P P + W KD+ + + Y +
Sbjct: 4166 HVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLL---ANLLGKYTAEPYG 4222
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
LI+ +V +D YTC A N+ GE T T L V +
Sbjct: 4223 ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVL 4259
Score = 45.8 bits (107), Expect = 4e-04
Identities = 61/259 (23%), Positives = 88/259 (33%), Gaps = 55/259 (21%)
Query: 1013 AGTTDNEKRSESQGTAPAFKQKLQ--DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1070
AGTT+ K + P K K Q +V V + L C+V P I+W + +
Sbjct: 1344 AGTTER-KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVT 1402
Query: 1071 TTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAP 1130
+ I G + + + +A PED G Y C A N AG ++ + V
Sbjct: 1403 ESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAINIAGTSQKYFNIDV------------ 1448
Query: 1131 EMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQII--QFPEDQKVRAGESVEL 1188
+PP II FP + V V L
Sbjct: 1449 -----------------------------------LVPPTIIGTNFPNEVSVVLNRDVAL 1473
Query: 1189 FGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248
+V GT W K K + + VE + G L + AR+ G Y V N G
Sbjct: 1474 ECQVKGTPFPDIHWFKDGKPLFLGD-PNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAG 1532
Query: 1249 SRQAQVNLTVVDKPDPPAG 1267
+ + LT+ P G
Sbjct: 1533 KQAKDIKLTIYIPPSIKGG 1551
Score = 45.8 bits (107), Expect = 4e-04
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRE-SRHFQIDYDEDGN 1744
HV P S + + VV + R +C+ G P P + W KD + S Q+ G
Sbjct: 2009 HVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQV---LSGG 2065
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGE 1770
L ++ D +YTC AVN+ GE
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGE 2091
Score = 45.8 bits (107), Expect = 4e-04
Identities = 39/142 (27%), Positives = 55/142 (38%), Gaps = 12/142 (8%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
GD VA++ S+ S+ L P L P I G + G P+
Sbjct: 4415 GDYTCVATNEAGVVERSM------SLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 62 PQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN--GSGARQVTV 119
P +TW R G I+ R + SL I +ED ++ C A N GS +V V
Sbjct: 4469 PTITWSRQGHSISWDDR----VNVLSNNSLYIADAQKEDTSEFECVARNLMGSVLVRVPV 4524
Query: 120 ELTVEGSFAKQLGQPVVSKTLG 141
+ V G F++ S T G
Sbjct: 4525 IVQVHGGFSQWSAWRACSVTCG 4546
Score = 45.4 bits (106), Expect = 5e-04
Identities = 34/118 (28%), Positives = 54/118 (45%), Gaps = 5/118 (4%)
Query: 1013 AGTTDNEKRSESQGTA---PAFKQK-LQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKT 1068
A T + + E + T P K L + V + K + LQC + P +I W + +
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 1069 LKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1126
+ T + + Q + I K L ED G Y CVA N AG+ + Q+ V + P+ E+
Sbjct: 1867 VNTAQGNLKIQSSGRV-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLED 1923
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 5/98 (5%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1756
++ V++GS+ C +G P P + W +D Q + H + L + +D
Sbjct: 3444 EITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTV---STHGMVLQLLKAETED 3500
Query: 1757 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
KYTC A N GE + I++ +E G EE E
Sbjct: 3501 SGKYTCIASNEAGEV--SKHFILKVLEPPHINGSEEHE 3536
Score = 45.1 bits (105), Expect = 6e-04
Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 10/155 (6%)
Query: 1625 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1684
WQK G V GR ++ GL ++ + + + + + + L
Sbjct: 4021 WQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV----- 4075
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
V P S +++ + C+ +G P P++ W KD ++I ES ++ +
Sbjct: 4076 -QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRV----LSS 4130
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
SL I+ V D YTC A N G ++ + +L V
Sbjct: 4131 GSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 44.7 bits (104), Expect = 8e-04
Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 3/76 (3%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1756
+L V G +CK G P P+V WFK D +R S ID L I + D
Sbjct: 710 ELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQETQDLD 766
Query: 1757 DAKYTCKAVNSLGEAT 1772
YTC A+N G AT
Sbjct: 767 AGDYTCVAINEAGRAT 782
Score = 44.7 bits (104), Expect = 8e-04
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Query: 1684 KPHVKPYFS--KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
K HV P + + ++ V+ C++EG P P ++W+KD+ + ES Q
Sbjct: 1354 KVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQ---TV 1410
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLG 1769
+ L + +D +Y+CKA+N G
Sbjct: 1411 NNGKILKLFRATPEDAGRYSCKAINIAG 1438
Score = 44.7 bits (104), Expect = 8e-04
Identities = 30/107 (28%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
PH+ T+ D++V E + C++ G P PE+ W KD Q ++E I G
Sbjct: 2478 PHIVG--ENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHI---ISGG 2532
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEE 1791
L I++V +YTC A + G + + L V G G +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSD 2579
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 3/106 (2%)
Query: 1686 HVKPYF-SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
HV P S + + VV+ C G P+P + W KDDQ + ++ + G
Sbjct: 1823 HVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQG-NLKIQSSGR 1881
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGE 1790
L I+ +D +YTC A N+ GE +L V E G+
Sbjct: 1882 V-LQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGK 1926
Score = 43.9 bits (102), Expect = 0.001
Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 1/98 (1%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1756
D+ V+ G C G P P + W KD + I +I +G+ +L I D
Sbjct: 3255 DVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS-TLNIYGALTSD 3313
Query: 1757 DAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
KYTC A N GE L V G +E E+
Sbjct: 3314 TGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEK 3351
Score = 43.5 bits (101), Expect = 0.002
Identities = 45/226 (19%), Positives = 82/226 (36%), Gaps = 48/226 (21%)
Query: 1037 DVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDR 1096
D+ V + L+C+ P I W +G+ + ++ + +G + I +A D
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQY--LHIPRAQVSDS 1613
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKK 1156
Y C N AG AE S V V P E A
Sbjct: 1614 ATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLAT-------------------------- 1647
Query: 1157 PAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMK 1216
P +++V S+ L K G TW+K ++ +++++
Sbjct: 1648 ------------------PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIR 1689
Query: 1217 VENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+E G KL I++A++ G Y + + G ++ + + V+ P
Sbjct: 1690 IE--AGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP 1733
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
+D+ V +++ L+C+ + PP I W NG+ L+ T + + G + I A D
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRY--LQINNADLGD 3686
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAP 1122
Y CVA N AG+ +TV+ P
Sbjct: 3687 TANYTCVASNIAGKTTREFILTVNVPP 3713
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 5/91 (5%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1756
D+ V+ S + +C+ G P P + W+KD Q I S Q Y + G L I D
Sbjct: 1556 DISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSS--QALYIDKGQ-YLHIPRAQVSD 1612
Query: 1757 DAKYTCKAVNSLG--EATCTAELIVETMEEG 1785
A YTC N G E + ++ V M EG
Sbjct: 1613 SATYTCHVANVAGTAEKSFHVDVYVPPMIEG 1643
Score = 43.1 bits (100), Expect = 0.002
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 4/87 (4%)
Query: 1686 HVKP-YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
HV P +L VV + C++ G+P P++ W K++Q I+ + + I G
Sbjct: 2961 HVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLI---VPGG 3017
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEA 1771
+L I D +YTC A+N GE+
Sbjct: 3018 RTLQIIRAKVSDGGEYTCIAINQAGES 3044
Score = 42.0 bits (97), Expect = 0.005
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 20/153 (13%)
Query: 1625 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESE-EDVSQAFLEAVAEE 1683
W+K G+ V SM + LSG G AEK ++ + + A++
Sbjct: 2230 WKKKGSPVLT----DSMGRVRILSG-----GRQLQISIAEKSDAALYSCVASNVAGTAKK 2280
Query: 1684 KPHVKPYFSKTIR-------DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ 1736
+ +++ Y TI ++ V G + +C+++G P P V W KD + +++ +
Sbjct: 2281 EYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340
Query: 1737 IDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1769
I D L + ++ D +Y C AVN G
Sbjct: 2341 I---LDEGHILQLKNIHVSDTGRYVCVAVNVAG 2370
Score = 41.6 bits (96), Expect = 0.007
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-DYDEDGNCSL 1747
P F + D+ + GS C ++GYP+P + W + D SR F + + +L
Sbjct: 793 PVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGAL 852
Query: 1748 IISDVCGDDDAKYTCKAVNSLGE 1770
I ++ D Y C+A N G+
Sbjct: 853 FILNLWASDKGTYICEAENQFGK 875
Score = 41.6 bits (96), Expect = 0.007
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 3/74 (4%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1756
D+ V+ S C+ YP + WFKD + +R+ +I G +L I + D+
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRI---LPGGRTLQILNAQEDN 2640
Query: 1757 DAKYTCKAVNSLGE 1770
+Y+C A N GE
Sbjct: 2641 AGRYSCVATNEAGE 2654
Score = 40.8 bits (94), Expect = 0.012
Identities = 22/74 (29%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDD 1756
++ VVE ++ C+ G P P + WFKD + S +I G L + +D
Sbjct: 2395 NISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRI---LSGGRMLRLMQTTMED 2451
Query: 1757 DAKYTCKAVNSLGE 1770
+YTC N+ GE
Sbjct: 2452 AGQYTCVVRNAAGE 2465
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/89 (28%), Positives = 41/89 (46%), Gaps = 5/89 (5%)
Query: 1686 HVKPYFSKTI--RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
HV P + T RD+ V+ +CK + P P + W ++ + ++ + +I G
Sbjct: 3617 HVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRI---LSG 3673
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEAT 1772
L I++ D A YTC A N G+ T
Sbjct: 3674 GRYLQINNADLGDTANYTCVASNIAGKTT 3702
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 1/95 (1%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
HV P + ++ V+ C+ G P P + W K+ + ++ Q Y +
Sbjct: 3801 HVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQN-QNSYRLLSSG 3859
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
SL+I DD A Y C N G+ T +L V+
Sbjct: 3860 SLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQ 3894
Score = 40.4 bits (93), Expect = 0.016
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 4/89 (4%)
Query: 1039 HVAEGKKLLLQCQV-SSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRG 1097
+V EG++L L C + + +P W N L +I + +GSL IE+ +D G
Sbjct: 900 NVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSL---HIERVQLQDGG 956
Query: 1098 LYKCVAKNDAGQAECSCQVTVDDAPASEN 1126
Y CVA N AG + V V P ++
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVLPTIQH 985
Score = 40.4 bits (93), Expect = 0.016
Identities = 34/150 (22%), Positives = 58/150 (38%), Gaps = 16/150 (10%)
Query: 1625 WQKTGNAVRAIGR----LSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAV 1680
W K G+ V + LS +++ S + S TG T E + D+
Sbjct: 2045 WLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-------- 2096
Query: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYD 1740
+ + +V P +++ V+ A C+ + P P + W KD + + I
Sbjct: 2097 -DLRVYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSI--- 2152
Query: 1741 EDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
+ L I D D +YTC+A N G+
Sbjct: 2153 SENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 39.7 bits (91), Expect = 0.027
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 3/93 (3%)
Query: 1700 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1759
V+ + DC + G P P ++W KD Q I E F+I + L+I+ +
Sbjct: 1746 VMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLN---GRKLVIAQAQVSNTGL 1802
Query: 1760 YTCKAVNSLGEATCTAELIVETMEEGEGEGEEE 1792
Y C A N+ G+ E+ V + G E
Sbjct: 1803 YRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSE 1835
Score = 39.3 bits (90), Expect = 0.035
Identities = 50/227 (22%), Positives = 81/227 (35%), Gaps = 50/227 (22%)
Query: 1036 QDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPED 1095
++V V K L++C S P W +G+ L G + + I D
Sbjct: 2880 EEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI--LQILNTQITD 2937
Query: 1096 RGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKK 1155
G Y CVA+N AG A+ + N P P V+G +S
Sbjct: 2938 IGRYVCVAENTAGSAKKYFNL---------NVHVP-----------PSVIGPKS------ 2971
Query: 1156 KPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHM 1215
E+ V + L +V+G P +W+K + I+ + +
Sbjct: 2972 --------------------ENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNT 3011
Query: 1216 KVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
+ G L I+ A+ G YT + N+ G + + +LTV P
Sbjct: 3012 LI--VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPP 3056
Score = 38.9 bits (89), Expect = 0.045
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 6/100 (6%)
Query: 1671 DVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR 1730
+VS+ F+ V E PH+ S+ ++ V+ + C G P P++ W KD + +
Sbjct: 3514 EVSKHFILKVLEP-PHING--SEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLP 3570
Query: 1731 ESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
++ Q G L IS +D +YTC A + G+
Sbjct: 3571 QTDQVQ---TLGGGEVLRISTAQVEDTGRYTCLASSPAGD 3607
Score = 38.5 bits (88), Expect = 0.059
Identities = 33/123 (26%), Positives = 48/123 (39%), Gaps = 10/123 (8%)
Query: 1675 AFLEAVAEEKPHVKPYFSKTIR-------DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQ 1727
A + AE+ HV Y I + +VV + +CK G P P + W KD
Sbjct: 1621 ANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGV 1680
Query: 1728 SIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEG 1787
++ + + +I E G L I D +Y C A + GE E+ V EG
Sbjct: 1681 PVKANDNIRI---EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEG 1737
Query: 1788 EGE 1790
E
Sbjct: 1738 GDE 1740
Score = 38.1 bits (87), Expect = 0.078
Identities = 85/475 (17%), Positives = 153/475 (32%), Gaps = 91/475 (19%)
Query: 808 VETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSEDDLKEIPAEQMDFRANLQRQVK-- 865
V+T ++R + +DFR +K + +DF+ + R V+
Sbjct: 299 VKTSSSGRHSVRITGLSTIDFRAGFSRKPT----------------LDFKKTVSRPVQGI 342
Query: 866 PKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPPPKPA-----TPDFRSVLGGKK 920
P V + +P ++D +L+ G+S +P K P + DF V +
Sbjct: 343 PTYVLLNTSGISTPARIDLLELLSISGSSLKTIPVKYYPHRKPYGIWNISDF--VPPNEA 400
Query: 921 KLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKP 980
G + L + SS S+ P P + P L+P ++L P
Sbjct: 401 FFLKVTGYDKDDYLFQRV--SSVSFSSIVPDAPKVTMPEKTPGYYLQPGQIPCSVDSLLP 458
Query: 981 MG--------NAKPDENLKSASKEELK--KDVKND---VNCKRGHAGTTDNEKRSESQGT 1027
D+ LK ++ L K +D C + T +
Sbjct: 459 FTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSE 518
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
P Q +V V G++ +L C + S + W N + ++ + + +L S+
Sbjct: 519 PPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANL-SLE 577
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
++ D G Y C+ ++ G + S +TV +
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQE--------------------------- 610
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
PP++ P++Q G V + TG W
Sbjct: 611 --------------------PPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDM 650
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
I S ++ + L I A + G Y L N G+ + L ++ P
Sbjct: 651 FIVGSHRYRMTSD---GTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAP 702
Score = 38.1 bits (87), Expect = 0.078
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS 1746
++P ++ T + E V F C +G P P + W + + + R I EDG
Sbjct: 1267 LEPPYNTTFQ--ERVANQRIEFPCPAKGTPKPTIKWLHNGRELT-GREPGISILEDGTL- 1322
Query: 1747 LIISDVCGDDDAKYTCKAVNSLG 1769
L+I+ V D+ +Y C AVN G
Sbjct: 1323 LVIASVTPYDNGEYICVAVNEAG 1345
Score = 38.1 bits (87), Expect = 0.078
Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 4/79 (5%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTC 1762
G A +C+++G P P + W + I S + + GN SL I +D YTC
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR----QLGNGSLAIYGTVNEDAGDYTC 4419
Query: 1763 KAVNSLGEATCTAELIVET 1781
A N G + L +++
Sbjct: 4420 VATNEAGVVERSMSLTLQS 4438
Score = 37.7 bits (86), Expect = 0.10
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 8/104 (7%)
Query: 1666 LESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKD 1725
+ SE S A + +E P V + ++ GS C GYP P++ W +
Sbjct: 593 VSSEGGSSAASVFLTVQEPPKV----TVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN 648
Query: 1726 DQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLG 1769
D I S +++ D +L I + D Y C A NS G
Sbjct: 649 DMFIVGSHRYRMTSDG----TLFIKNAAPKDAGIYGCLASNSAG 688
Score = 37.0 bits (84), Expect = 0.17
Identities = 57/271 (21%), Positives = 90/271 (33%), Gaps = 60/271 (22%)
Query: 1008 CKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK 1067
C +A TD + P+ ++ V + L C+ + P +I W NG
Sbjct: 3783 CMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGH 3842
Query: 1068 TLKT----TKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
L + +LS GSL +S +D Y+C N AG + + +TV
Sbjct: 3843 LLNVDQNQNSYRLLS-SGSLVIIS---PSVDDTATYECTVTNGAGDDKRTVDLTV----- 3893
Query: 1124 SENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAG 1183
+PP + E + K AP A + FP + G
Sbjct: 3894 ----------------QVPPSIADEPTDFLVTKHAPAVITCTASG---VPFPSIHWTKNG 3934
Query: 1184 ESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLV 1243
+ L + G + + + + ILA + H G YT +
Sbjct: 3935 --IRLLPRGDGYRIL-----------------------SSGAIEILATQLNHAGRYTCVA 3969
Query: 1244 ENKLGSRQAQVNLTVVDKPDPPAGTPCASDI 1274
N GS V L V +PP P S++
Sbjct: 3970 RNAAGSAHRHVTLHV---HEPPVIQPQPSEL 3997
Score = 36.2 bits (82), Expect = 0.29
Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 11/97 (11%)
Query: 1682 EEKPHVKPYFSK--------TIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR 1733
E K ++ P +K + +++++ + +C+ P + W+KD Q ++
Sbjct: 2660 EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD 2719
Query: 1734 HFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGE 1770
H I +L I + D +YTC A N GE
Sbjct: 2720 HVNI---AANGHTLQIKEAQISDTGRYTCVASNIAGE 2753
Score = 35.8 bits (81), Expect = 0.38
Identities = 22/89 (24%), Positives = 39/89 (43%), Gaps = 6/89 (6%)
Query: 1694 TIRDLEVVEGSAARF--DCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1751
T+ +E V + + +C+ G P P + W + SI + N SL I+D
Sbjct: 4443 TLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVL----SNNSLYIAD 4498
Query: 1752 VCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+D +++ C A N +G +IV+
Sbjct: 4499 AQKEDTSEFECVARNLMGSVLVRVPVIVQ 4527
Score = 35.4 bits (80), Expect = 0.50
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 3/84 (3%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
HV P + + L+V G C +G P P + W K ++ + + DG
Sbjct: 1168 HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVS-NPDG-- 1224
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLG 1769
+L I D YTC A N G
Sbjct: 1225 TLSIDQATPSDAGIYTCVATNIAG 1248
Score = 35.0 bits (79), Expect = 0.66
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 1700 VVEGSAARFDCKI-EGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1758
V+EG C + G P PE W K+ + ++ + + D SL I V D
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG----SLHIERVQLQDGG 956
Query: 1759 KYTCKAVNSLGEATCTAELIVETM 1782
+YTC A N G T ++V +
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHVL 980
Score = 35.0 bits (79), Expect = 0.66
Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 7/85 (8%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIR--ESRHFQIDYDEDGNCSLIISDVCG 1754
++ V+ G C+++ P P + W K+ Q I RH + + S+ I++
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLP-----SGSMKITETRT 1142
Query: 1755 DDDAKYTCKAVNSLGEATCTAELIV 1779
D Y C A N G T +L V
Sbjct: 1143 SDSGMYLCVATNIAGNVTQAVKLNV 1167
Score = 34.7 bits (78), Expect = 0.86
Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 1685 PHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGN 1744
P +K S ++ V+ +A +C G P P W KD Q + E H + + +G
Sbjct: 2869 PIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHK--FLSNGR 2926
Query: 1745 CSLIISDVCGDDDAKYTCKAVNSLGEA 1771
I++ D +Y C A N+ G A
Sbjct: 2927 ILQILNTQI-TDIGRYVCVAENTAGSA 2952
Score = 34.7 bits (78), Expect = 0.86
Identities = 31/115 (26%), Positives = 48/115 (41%), Gaps = 7/115 (6%)
Query: 1663 AEKLESEEDVSQAFLEAVAEEKP-HVKPYFSKTIRDLE---VVE--GSAARFDCKIEGYP 1716
AE ++ + V +A A ++K H+ Y +I E +VE + C G P
Sbjct: 3120 AEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIP 3179
Query: 1717 DPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1771
P + W K+ + I S ++ G L I+ D YTC A N G+A
Sbjct: 3180 PPTIAWLKNHKRIENSDSLEVRI-LSGGSKLQIARSQHSDSGNYTCIASNMEGKA 3233
Score = 34.3 bits (77), Expect = 1.1
Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 1/80 (1%)
Query: 1692 SKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISD 1751
S + L V+EG+ C+ G P P ++W K + ++ G L IS
Sbjct: 2200 SDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGR-QLQISI 2258
Query: 1752 VCGDDDAKYTCKAVNSLGEA 1771
D A Y+C A N G A
Sbjct: 2259 AEKSDAALYSCVASNVAGTA 2278
Score = 34.3 bits (77), Expect = 1.1
Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 3/72 (4%)
Query: 1699 EVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDA 1758
+V+ + C+ P P + W+KD + S I G L I +D
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLI---LPGGRVLQIPRAKVEDAG 2844
Query: 1759 KYTCKAVNSLGE 1770
+YTC AVN GE
Sbjct: 2845 RYTCVAVNEAGE 2856
Score = 34.3 bits (77), Expect = 1.1
Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 3/84 (3%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
+V P + L ++ + +C EG P P + W KD ++ H + E+G
Sbjct: 3710 NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDG-AVLAGNHARYSILENG-- 3766
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLG 1769
L I D +Y C A N+ G
Sbjct: 3767 FLHIQSAHVTDTGRYLCMATNAAG 3790
Score = 33.1 bits (74), Expect = 2.5
Identities = 24/95 (25%), Positives = 35/95 (36%), Gaps = 3/95 (3%)
Query: 1686 HVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC 1745
H P +L V+ + C+ G P P + W K+ ++ S G
Sbjct: 3985 HEPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-- 4042
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
L IS +D Y C A N G A +L V+
Sbjct: 4043 -LQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQ 4076
Score = 32.3 bits (72), Expect = 4.3
Identities = 19/90 (21%), Positives = 39/90 (43%), Gaps = 16/90 (17%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI-------I 1749
++ VV +C+++G P P++ WFKD + + + D N L+ +
Sbjct: 1462 EVSVVLNRDVALECQVKGTPFPDIHWFKDGKPL---------FLGDPNVELLDRGQVLHL 1512
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ +D +Y C N+ G+ +L +
Sbjct: 1513 KNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 31.6 bits (70), Expect = 7.3
Identities = 19/70 (27%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 1700 VVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAK 1759
V+ + + +CK G P P + W+KD++ + S + + G + I D
Sbjct: 1932 VLVSNPVQLECKAAGNPVPVITWYKDNRLLSGST--SMTFLNRGQI-IDIESAQISDAGI 1988
Query: 1760 YTCKAVNSLG 1769
Y C A+NS G
Sbjct: 1989 YKCVAINSAG 1998
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 154 bits (390), Expect = 6e-37
Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 55/325 (16%)
Query: 1389 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1447
+ + ++ +E LG+G F +V EK T K++A K + K KE+ I EI+++ +
Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76
Query: 1448 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1507
H +V D +E ++ +V+++VSGGELF+RI+++ F TE++ +RQ+ + V Y+
Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135
Query: 1508 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1566
H+ GIVH DLKPEN++ ++ ++I + DFGL++ + GTP +VAPEV+
Sbjct: 136 HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195
Query: 1567 EPIGYATDMWSIGVICYIL----------------------------------------- 1585
+P A D WSIGVI YIL
Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 1586 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1634
R C Q +HPW+ DT N + +++K A+ KW++ NA
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315
Query: 1635 IGRLSSMAMISGLSGRKSSTGSPTS 1659
+ + + + S L +S S S
Sbjct: 316 VRHMRKLHLGSSLDSSNASVSSSLS 340
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform 2
[Homo sapiens]
Length = 385
Score = 154 bits (390), Expect = 6e-37
Identities = 95/325 (29%), Positives = 156/325 (48%), Gaps = 55/325 (16%)
Query: 1389 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKEN-IRQEISIMNCL 1447
+ + ++ +E LG+G F +V EK T K++A K + K KE+ I EI+++ +
Sbjct: 17 EDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKI 76
Query: 1448 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1507
H +V D +E ++ +V+++VSGGELF+RI+++ F TE++ +RQ+ + V Y+
Sbjct: 77 KHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGF-YTEKDASTLIRQVLDAVYYL 135
Query: 1508 HKQGIVHLDLKPENIMCVNKTG-TRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINY 1566
H+ GIVH DLKPEN++ ++ ++I + DFGL++ + GTP +VAPEV+
Sbjct: 136 HRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQ 195
Query: 1567 EPIGYATDMWSIGVICYIL----------------------------------------- 1585
+P A D WSIGVI YIL
Sbjct: 196 KPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDF 255
Query: 1586 ----------NRLDCTQCLQHPWLMKDTK-NMEAKKLSKDRMKKYMARRKWQKTGNAVRA 1634
R C Q +HPW+ DT N + +++K A+ KW++ NA
Sbjct: 256 IRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAV 315
Query: 1635 IGRLSSMAMISGLSGRKSSTGSPTS 1659
+ + + + S L +S S S
Sbjct: 316 VRHMRKLHLGSSLDSSNASVSSSLS 340
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 151 bits (381), Expect = 6e-36
Identities = 88/298 (29%), Positives = 148/298 (49%), Gaps = 53/298 (17%)
Query: 1389 QKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCLH 1448
+K+ FY+++E +G G FG V R+ K + + A KF S + R+ I+ L
Sbjct: 6462 RKLHSFYEVKEEIGRGVFGFVKRVQHKGNKILCAAKFIPLRSRTRAQAYRER-DILAALS 6520
Query: 1449 HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH 1508
HP + +D FE + ++++LE+ S EL +R+ + +TE E Y++Q+ EG+ Y+H
Sbjct: 6521 HPLVTGLLDQFETRKTLILILELCSSEELLDRLYRKGV-VTEAEVKVYIQQLVEGLHYLH 6579
Query: 1509 KQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEP 1568
G++HLD+KP NI+ V+ IK+ DFG A+ + A +G+PEFV+PE+I P
Sbjct: 6580 SHGVLHLDIKPSNILMVHPAREDIKICDFGFAQNITPAELQFSQYGSPEFVSPEIIQQNP 6639
Query: 1569 IGYATDMWSIGVICY-----------------ILNRLD---------------------- 1589
+ A+D+W++GVI Y +LN L+
Sbjct: 6640 VSEASDIWAMGVISYLSLTCSSPFAGESDRATLLNVLEGRVSWSSPMAAHLSEDAKDFIK 6699
Query: 1590 ------------CTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAI 1635
QCL HPW +K EA ++ ++K +AR +WQ++ + ++I
Sbjct: 6700 ATLQRAPQARPSAAQCLSHPWFLKSMPAEEAHFINTKQLKFLLARSRWQRSLMSYKSI 6757
Score = 124 bits (312), Expect = 6e-28
Identities = 147/662 (22%), Positives = 244/662 (36%), Gaps = 112/662 (16%)
Query: 129 KQLGQPVVSKTLGDRFSA-PAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGR 187
K LG P + K +A + R + + P F+ G + G R C + +
Sbjct: 4865 KDLGDPSMDKAAVKIQAAFKGYKVRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASK 4924
Query: 188 PQPQVTWLKGNVPLQPSARVSVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
+ WLK V L + + +G L I G+++ D G YTC V N G+ + SA
Sbjct: 4925 ADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSA 4984
Query: 247 ELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSP 306
+ + G +S S + D + + + + S + + S G +
Sbjct: 4985 CVVVSGSESEAES---SSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAE 5041
Query: 307 P-----WAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGL 361
P W + + + E+ ++ + + + T I ++ V+ PR +
Sbjct: 5042 PEEPADWQTYREDEHFICIRFEALTEARQAVTRFQEMFAT-LGIGVEIKLVEQGPRRVEM 5100
Query: 362 GVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQ 421
+ ++ PAP P P P L + D A P F ++ Q
Sbjct: 5101 CI------SKETPAPVVP---PEPLPSLLTSD------------------AAPVFLTELQ 5133
Query: 422 SQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLN 481
+QEV++ V F C V G P+P + W +
Sbjct: 5134 NQEVQDGYPVSF-------------------------------DCVVTGQPMPSVRWFKD 5162
Query: 482 GQPIQ----YARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH----- 532
G+ ++ Y + + G +L I +P D G Y CLAEN++G S A + V
Sbjct: 5163 GKLLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTD 5222
Query: 533 --------EKKSSRKSEYLLPVAPSKPT--------APIFLQGLSDLKVMDGSQVT-MTV 575
E S ++ L + T P ++ L DL+V G+++ +
Sbjct: 5223 YDTAADATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQL 5282
Query: 576 QVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEV 635
+V G P P + W +G + S + H+L I V ED+G Y N+ G
Sbjct: 5283 KVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA 5342
Query: 636 RTQAVLTVQEPHDGTQ------------PWFISKPRSVTASLGQSVLISCAIAGDPFPTV 683
+ A L V+ P + + P + + G S+ S + G P PTV
Sbjct: 5343 YSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTV 5402
Query: 684 HWLRDGKA-----LCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738
HWLR+ + DT + V + +LVL V H G Y + N G+ C
Sbjct: 5403 HWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSA 5462
Query: 739 SL 740
SL
Sbjct: 5463 SL 5464
Score = 117 bits (294), Expect = 8e-26
Identities = 123/460 (26%), Positives = 197/460 (42%), Gaps = 54/460 (11%)
Query: 1146 GTESDATVKKKPAPKTPPKAAMP-----PQIIQFPEDQKVRAGESVELFGKVTGTQPITC 1200
G E + +KKP + + + P ++ D+ V G+SV L +V+
Sbjct: 7435 GLEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQA 7494
Query: 1201 TWMKFRKQIQESEHMKVENS-ENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLT-V 1258
TW K ++ S + + + +N LTIL E G YT V N LG+ V T V
Sbjct: 7495 TWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGT----VTTTGV 7550
Query: 1259 VDKPDPPAGTPCAS--DIRSSSLTLSWYG-SSYDGGSAVQSYSIEIWDSANKTWKELAT- 1314
+ K + P+ +PC ++ + + L W SY + + S+E +W LA+
Sbjct: 7551 LRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVTYIVQCSLE-----GGSWTTLASD 7605
Query: 1315 ----CRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSD 1370
C TS L Y FR ++ G S SE +G P E E S
Sbjct: 7606 IFDCCYLTS----KLSRGGTYTFRTACVSKAGMGPYSSPSEQVLLGG-PSHLASEEE-SQ 7659
Query: 1371 DDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYS 1430
+P +T T+ + G+F V + EK + + A K Y
Sbjct: 7660 GRSAQPLPSTKTFAFQTQ------------IQRGRFSVVRQCWEKASGRALAAKIIP-YH 7706
Query: 1431 AKEKENIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTE 1490
K+K + +E + L HP L Q A+ ++V++LE+ SG EL + E +E
Sbjct: 7707 PKDKTAVLREYEALKGLRHPHLAQLHAAYLSPRHLVLILELCSGPELLP-CLAERASYSE 7765
Query: 1491 RECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLK 1550
E Y+ Q+ +Y+H Q I+HLDL+ EN++ +K++D G A+ L K
Sbjct: 7766 SEVKDYLWQMLSATQYLHNQHILHLDLRSENMIITEY--NLLKVVDLGNAQSLSQE---K 7820
Query: 1551 VLFGTP-----EFVAPEVINYEPIGYATDMWSIGVICYIL 1585
VL E +APE++ + TD+W+IGV +I+
Sbjct: 7821 VLPSDKFKDYLETMAPELLEGQGAVPQTDIWAIGVTAFIM 7860
Score = 111 bits (278), Expect = 6e-24
Identities = 126/538 (23%), Positives = 203/538 (37%), Gaps = 106/538 (19%)
Query: 26 SMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGI 85
++P+ P F + + G T K RV G P+P ++W+++G+ + +L
Sbjct: 6007 ALPVWRPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDP 6066
Query: 86 RGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFS 145
G+ +L++ ++ D G+Y C A + +G TLG
Sbjct: 6067 DGSCALILDSLTGVDSGQYMCFAASAAGN----------------------CSTLG---- 6100
Query: 146 APAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSA 205
I + PP+F K+ EG+ +F+C I G P PQ+ W K L
Sbjct: 6101 --------KILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGN 6152
Query: 206 RV-SVSE-KNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG--LDSANRSFV 261
+ ++SE ++G+ VL I +++D+G+Y C +VN G A SAEL IQ L + +
Sbjct: 6153 KFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHR 6212
Query: 262 RETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESK 321
+ A D E + E + K P+ G P
Sbjct: 6213 EQLVAAVEDTTLERAD----------QEVTSVLKRLLGPKAPG------------PSTGD 6250
Query: 322 LESCKDSPRTAPQTPVLQKTSSSITLQAARVQP--EPRAPGLGVLSPSGEERKRPAPPRP 379
L PR A P LQ+T S + P PR P + +E + A +
Sbjct: 6251 LTGPGPCPRGA---PALQETGSQPPVTGTSEAPAVPPRVPQPLLHEGPEQEPEAIARAQE 6307
Query: 380 ATFPTRQ-----PGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFR 434
T P R PG G+ +++ + + QR + ++
Sbjct: 6308 WTVPIRMEGAAWPGAGTGELLWDVHSHVVRETTQRTYTYQAIDTHTAR------------ 6355
Query: 435 CEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARST--- 491
PS ++D G + + G P P +TW + +Q ST
Sbjct: 6356 ---------PPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDS--VQLVDSTRLS 6404
Query: 492 --CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTV--------HEKKSSRK 539
E L ++ +D G YTCLA+N GQV C A + V EK+S R+
Sbjct: 6405 QQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSEKQSHRR 6462
Score = 109 bits (273), Expect = 2e-23
Identities = 127/537 (23%), Positives = 191/537 (35%), Gaps = 99/537 (18%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
P+F T+ VV G+ SC+I G P PQV+W K P+ AR +++ + L I
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69
Query: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
+ D G Y C N G+A + L + + ++ + +
Sbjct: 70 LDLALGDSGQYVCRARNAIGEAFAAVGLQVDA---------------EAACAEQAPHFLL 114
Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQK 340
+ + + E + + C + GGSP A + R + D PR +
Sbjct: 115 RPTSIRVREGSEATFRC---RVGGSPRPAVSWSKDGRRLGE----PDGPRVRVEE---LG 164
Query: 341 TSSSITLQAARVQPEPRAPG---LGVLSPSGEERKRPA--PPRPATFPTRQPGLGSQDVV 395
+S++ ++AAR PR G + +P G A A +PG + ++
Sbjct: 165 EASALRIRAAR----PRDGGTYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALL 220
Query: 396 SKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCA 455
+ RR M + A P S+ + C
Sbjct: 221 AHLQRRREAMRAEGAPASPP--------------------------------STGTRTCT 248
Query: 456 VIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAE----LHIQDALPEDHGT 511
V EG+ L C V G P P W +GQ + R A+ L I D G
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGL 308
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 571
YTC A N +GQ S V V E P P F + L DL+V +
Sbjct: 309 YTCTASNLVGQTYSSVLVVVRE-----------------PAVP-FKKRLQDLEVREKESA 350
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
T +V P E W + S + E+ GT+ L ++ V +D Y CE
Sbjct: 351 TFLCEVP-QPSTEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEG 409
Query: 632 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 688
+ RT A L VQ PR +G + + C P VHWLR+
Sbjct: 410 S---RTVAELAVQ------GNLLRKLPRKTAVRVGDTAMF-CVELAVPVGPVHWLRN 456
Score = 107 bits (266), Expect = 1e-22
Identities = 218/1015 (21%), Positives = 380/1015 (37%), Gaps = 179/1015 (17%)
Query: 432 KFRCEGLAVMEVAPS-FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW------LLNGQ- 483
K R + + PS F L++ EG L C + + + W L +G
Sbjct: 3700 KERTSAMLTVRAMPSKFIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDR 3757
Query: 484 -PIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEY 542
++ S CE + L + DA G Y+C+ GQ SA +TV
Sbjct: 3758 HSLRQDGSRCELQIRGLAVVDA-----GEYSCVC----GQERTSATLTVRA--------- 3799
Query: 543 LLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHF 602
LP F++ + + + +G+ + ++S P E W ++ + +
Sbjct: 3800 -LPAR--------FIEDVKNQEAREGATAVLQCELSKAAPVE--WRKGSETLRGGDRYSL 3848
Query: 603 EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVT 662
Q GT+ L I + DTG Y+C G+ RT A LTV+ P QP F +S+
Sbjct: 3849 RQDGTRCELQIHGLSVADTGEYSCVC----GQERTSATLTVRAP----QPVFREPLQSLQ 3900
Query: 663 ASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQ 722
A G + + C ++ +P TV W + G L + G E LVL+ +Q G+
Sbjct: 3901 AEEGSTATLQCELS-EPTATVVWSKGGLQL-QANGRREPRLQGCTAELVLQDLQREDTGE 3958
Query: 723 YEILLKNRVGECSCQVSL----MLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRYG 778
Y ++ + V+ L+ + + G C +L G + R G
Sbjct: 3959 YTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEW----RKG 4014
Query: 779 SLRPGWPARGQGWLEEEDGED--VRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGK-K 835
SL+ +P +++ + VRGV + + +T + Q + L R K K
Sbjct: 4015 SLQL-FPCAKYQMVQDGAAAELLVRGV--EQEDAGDYTCDTGHTQSMASLSVRVPRPKFK 4071
Query: 836 VSTKTLSED--DLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGT 893
++L ++ D+ + + D + Q + V ++H+ + + RS +G
Sbjct: 4072 TRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGV-----ELHAGPKYEMRS----QGA 4122
Query: 894 SKTPVPEKVPPPKPATPDFRSVLGGKK----------KLPAENGSSSAETLNAKAVESSK 943
++ + ++ T ++ V GG+K ++ G AE + VE S
Sbjct: 4123 TRELLIHQLEAKD--TGEYACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSC 4180
Query: 944 PLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVK 1003
+S A +G ++ P ++ + A D + + LK
Sbjct: 4181 EVSRAGATG-------------VQWCLQGLPLQSNEVTEVAVRDGRIHTL---RLKGVTP 4224
Query: 1004 NDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWT 1063
D H G + + + + LQDV ++EG+ QC++S W
Sbjct: 4225 EDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWA 4284
Query: 1064 LNGKTLKTTKFI-ILSQEGSLCSVSIEKALPEDRGLY-------------KCVAKN---- 1105
L G L+ + I ++G+L +++ K ED G K AKN
Sbjct: 4285 LGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNTVVR 4344
Query: 1106 --------DAGQAECSCQVT----------VDDAPA--SENTKAPE----------MKSR 1135
+ G+A CQ++ +DD P SEN + +K+
Sbjct: 4345 GLENVEALEGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNL 4404
Query: 1136 RPKSS-----LPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG 1190
RP+ S L + T + TV+ +I++ ++ VRAG
Sbjct: 4405 RPQDSCRVTFLAGDMVTSAFLTVR-----------GWRLEILEPLKNAAVRAGAQACFTC 4453
Query: 1191 KVTGTQPI-TCTWMKFRKQIQ-ESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLG 1248
++ P+ +W +Q + V + L + +A+ H G T + +
Sbjct: 4454 TLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVA 4513
Query: 1249 SRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKT 1308
S + LTV+ PDPP + S ++TLSW DGG + Y +E+ + A
Sbjct: 4514 SAR----LTVLGLPDPPEDAEVVAR-SSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQ 4568
Query: 1309 WK---ELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPE 1360
W+ EL V L P Y+FRV A+ G EP + + E P+
Sbjct: 4569 WRLCHELVP--GPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPK 4621
Score = 103 bits (256), Expect = 2e-21
Identities = 84/337 (24%), Positives = 132/337 (39%), Gaps = 53/337 (15%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELH 500
AP F + K V G+D L C + G P P+++W + QP+ R + + L
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
I D D G Y C A NA+G+ + + V + A AP FL
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE------------AACAEQAPHFLLRP 116
Query: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESED--FHFEQRGTQHSLCIQEVFP 618
+ ++V +GS+ T +V G+P P V W +G + E + E+ G +L I+ P
Sbjct: 117 TSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARP 176
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASL------------- 665
D GTY A N G A L V T S+P + TA+L
Sbjct: 177 RDGGTYEVRAENPLGAASAAAALVVDSDAADT----ASRPGTSTAALLAHLQRRREAMRA 232
Query: 666 -------------------GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNED 706
G+ +SC + G+P P W +DG+ + + H ++
Sbjct: 233 EGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQE 292
Query: 707 VFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQ 743
F L + + G Y N VG+ V ++++
Sbjct: 293 NFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR 329
Score = 102 bits (255), Expect = 3e-21
Identities = 182/773 (23%), Positives = 282/773 (36%), Gaps = 142/773 (18%)
Query: 60 PEPQVTWHRNGQPITSGGR--FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATN------- 110
PE V W ++G + + FL G RG LV+H V ED G YTC +
Sbjct: 2673 PEAHVVWRKDGVQLGPSDKYDFLHTAGTRG---LVVHDVSPEDAGLYTCHVGSEETRARV 2729
Query: 111 -------GSGARQVTVELTVEG---SFAKQLGQPVVS---------KTLGD--RFSAPAV 149
G R T+E+ +EG SF L S KT+G RF A
Sbjct: 2730 RVHDLHVGITKRLKTMEV-LEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQ 2788
Query: 150 ---------ETRPSIWGEC--PPKFATKLGRVVVKE----------------GQMGRFSC 182
E PS GE + T ++V+E G+ C
Sbjct: 2789 GRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRC 2848
Query: 183 KITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKA 242
+++ P V WLK ++ S + V + M +L I G + D G YTC V A
Sbjct: 2849 ELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVEASKSTA 2907
Query: 243 SMSAE------------LSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEA 290
S+ E L ++ +A + E A RK + + + S E
Sbjct: 2908 SLHVEEKANCFTEELTNLQVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEG 2967
Query: 291 AAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAA 350
S+ ++ S + + R L + V + SS T +
Sbjct: 2968 LTLRLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRC- 3026
Query: 351 RVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
R+ P P L K P QPG V++ R++ + +D
Sbjct: 3027 RISPANYEPVHWFLD------KTPLHANELNEIDAQPG--GYHVLTL---RQLAL---KD 3072
Query: 411 SAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRG 470
S FE+ Q L V E FS L D + EG+D L C
Sbjct: 3073 SGTIYFEAGDQRASA-----------ALRVTEKPSVFSRELTDATITEGEDLTLVCETST 3121
Query: 471 TPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSA 527
+P + W +G+ ++ + + + E A+L I A +D G Y C A G S+
Sbjct: 3122 CDIP-VCWTKDGKTLRGSARCQLSHEGHRAQLLITGATLQDSGRYKCEA----GGACSSS 3176
Query: 528 WVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW 587
V VH + PV F + L DL+V++G T+ +S P V W
Sbjct: 3177 IVRVHAR----------PVR--------FQEALKDLEVLEGGAATLRCVLSSVAAP-VKW 3217
Query: 588 LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647
+ N ++ + + Q G L ++ + P+D+G Y+C S G+ T A LTV
Sbjct: 3218 CYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSC----SFGDQTTSATLTV---- 3269
Query: 648 DGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDV 707
FI K R+ A+ G + + C ++ V W R G +D + + Q+ +
Sbjct: 3270 TALPAQFIGKLRNKEATEGATATLRCELS--KAAPVEW-RKGSETLRDGDRYCLRQDGAM 3326
Query: 708 FTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCE 760
L ++ + A +Y + GE SL ++ A + R R S E
Sbjct: 3327 CELQIRGLAMVDAAEYSCV----CGEERTSASLTIRPMPAHFIGRLRHQESIE 3375
Score = 92.8 bits (229), Expect = 3e-18
Identities = 67/245 (27%), Positives = 112/245 (45%), Gaps = 10/245 (4%)
Query: 19 VDPSRVDSMPLTEA-PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGG 77
V P + S+ ++A P F+ +N +++G F+ V G P P V W ++G+ +
Sbjct: 5111 VPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDD 5170
Query: 78 RFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVS 137
++++ +G L+I AV D G Y C A N G EL V+ + + +
Sbjct: 5171 HYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLT-STDYDTAADA 5229
Query: 138 KTLGDRFSAPA-VETRPSIWGECP------PKFATKLGRVVVKEG-QMGRFSCKITGRPQ 189
FSA + +R E P+ +L + V G ++ +F K+ G P
Sbjct: 5230 TESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPA 5289
Query: 190 PQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELS 249
P++ W K PL SA + +++K + LEI V ++D G Y + N G A SA L
Sbjct: 5290 PRLYWFKDGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLL 5349
Query: 250 IQGLD 254
++G D
Sbjct: 5350 VRGPD 5354
Score = 91.7 bits (226), Expect = 6e-18
Identities = 59/214 (27%), Positives = 91/214 (42%), Gaps = 15/214 (7%)
Query: 548 PSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGT 607
P AP FL V G T++ Q+ GNP P+V W + + F Q G
Sbjct: 4 PQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD 63
Query: 608 QHSLCIQEVFPEDTGTYTCEAWNSAGE--------VRTQAVLTVQEPHDGTQPWFISKPR 659
+ L I ++ D+G Y C A N+ GE V +A Q PH F+ +P
Sbjct: 64 LYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACAEQAPH------FLLRPT 117
Query: 660 SVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTG-HFEVLQNEDVFTLVLKKVQPW 718
S+ G C + G P P V W +DG+ L + G V + + L ++ +P
Sbjct: 118 SIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPR 177
Query: 719 HAGQYEILLKNRVGECSCQVSLMLQNSSARALPR 752
G YE+ +N +G S +L++ + +A R
Sbjct: 178 DGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211
Score = 87.4 bits (215), Expect = 1e-16
Identities = 68/215 (31%), Positives = 93/215 (43%), Gaps = 24/215 (11%)
Query: 445 PSFSSVLKDCAVIEGQDFV-LQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 500
P L+D V G Q V+G P PR+ W +GQP+ + R T + + L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHTLE 5319
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVH------EKKSSRKSEYLLPVAPSKPTAP 554
I ED G Y NA+G SA + V EK +S E L+P P
Sbjct: 5320 IISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVP--------P 5371
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI------QESEDFHFEQRGTQ 608
L+ + KV GS +T +V+V G P P V WL E ++ + Q
Sbjct: 5372 RMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQ 5431
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV 643
HSL + +V + GTYTC A N+AG+ A L V
Sbjct: 5432 HSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHV 5466
Score = 87.0 bits (214), Expect = 1e-16
Identities = 67/233 (28%), Positives = 102/233 (43%), Gaps = 31/233 (13%)
Query: 31 EAPAFILPPRNLCIKEGAT-AKFEGRVRGYPEPQVTWHRNGQPITSGGRF-LLDCGIRGT 88
+ P + R+L + G AKF+ +V+GYP P++ W ++GQP+T+ + D I T
Sbjct: 5258 QLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMTDKKILHT 5317
Query: 89 FSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPA 148
++ +V ED G+Y +N GA + L V G + PA
Sbjct: 5318 LEII--SVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE--------------EKPA 5361
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNV--------P 200
+ + PP+ + VK+G FS K+ GRP P V WL+ P
Sbjct: 5362 SDVHEQL---VPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418
Query: 201 LQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
P V+ S + VL V + G YTC+ N +G+A SA L + GL
Sbjct: 5419 DTPGYTVASSAQQHSLVL--LDVGRQHQGTYTCIASNAAGQALCSASLHVSGL 5469
Score = 82.8 bits (203), Expect = 3e-15
Identities = 66/239 (27%), Positives = 94/239 (39%), Gaps = 32/239 (13%)
Query: 24 VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDC 83
+D + AP F+ P+ + G A ++ G P PQV+W ++ QP+ +G RF L
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRL-A 59
Query: 84 GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDR 143
+ L I + D G+Y C A N G V L V+ A
Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAA--------------- 104
Query: 144 FSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL-Q 202
E P F + + V+EG F C++ G P+P V+W K L +
Sbjct: 105 ------------CAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGE 152
Query: 203 PSA-RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI--QGLDSANR 258
P RV V E L I D G Y N G AS +A L + D+A+R
Sbjct: 153 PDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADTASR 211
Score = 82.0 bits (201), Expect = 5e-15
Identities = 55/199 (27%), Positives = 87/199 (43%), Gaps = 9/199 (4%)
Query: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQ-ESEDFHFEQRGTQHSLC 612
P F + L+D G V + +V+G P P + W +G +Q + E +L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLIS 672
+ + D+G Y C A ++AG T + VQ P P F++K R+ G+ +
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP-----PRFVNKVRASPFVEGEDAQFT 6128
Query: 673 CAIAGDPFPTVHWLRDGKALCKDTGHFEVLQ--NEDVFTLVLKKVQPWHAGQYEILLKNR 730
C I G P+P + W +DG AL F+ L + LV++ G YE L NR
Sbjct: 6129 CTIEGAPYPQIRWYKDG-ALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNR 6187
Query: 731 VGECSCQVSLMLQNSSARA 749
+G L +Q+ +A
Sbjct: 6188 LGSARASAELRIQSPMLQA 6206
Score = 80.9 bits (198), Expect = 1e-14
Identities = 136/596 (22%), Positives = 203/596 (34%), Gaps = 68/596 (11%)
Query: 191 QVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGS---GKASMSAE 247
+V W KG +QP R V + Q+L I G +D G Y C + GS A+
Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHCGLAQGSICPAAATFQVA 4712
Query: 248 LSIQGLDSANRSFVRETKATNSDVR-----KEVTNVISKESKLDSLEAAAKSKNCSS--P 300
LS +D A + + A D+ +S+E LDS+ + S P
Sbjct: 4713 LSPASVDEAPQPSLPPEAAQEGDLHLLWEALARKRRMSREPTLDSISELPEEDGRSQRLP 4772
Query: 301 QRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITL--QAARVQPEPRA 358
Q + E D T+ T S +T +A R P A
Sbjct: 4773 QEAEEVAPDLSEGYSTADELARTGDADLSHTSSDDESRAGTPSLVTYLKKAGRPGTSPLA 4832
Query: 359 PGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFES 418
+G + + ++ P A +P LG D+ +K + D A K ++
Sbjct: 4833 SKVGAPAAPSVKPQQQQEPLAAV----RPPLG--DLSTKDLG-----DPSMDKAAVKIQA 4881
Query: 419 KPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW 478
+ +V++ + P FS D G L+C V R W
Sbjct: 4882 AFKGYKVRKEMK----------QQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARW 4931
Query: 479 LLNGQPIQYAR----STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEK 534
L +G + R G L I D G YTC N GQV+ SA V V
Sbjct: 4932 LKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGS 4991
Query: 535 KSSRKSEYLLPVAPSKPTAPIFLQGL----SDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
+S +S + + A L L S +V D + P W
Sbjct: 4992 ESEAESSSGGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADW--- 5048
Query: 591 GNEIQESEDF---HFE--QRGTQHSLCIQEVFPE----------DTGTYTCEAWNSAGEV 635
+E E F FE Q QE+F + G E S
Sbjct: 5049 -QTYREDEHFICIRFEALTEARQAVTRFQEMFATLGIGVEIKLVEQGPRRVEMCISK--- 5104
Query: 636 RTQAVLTVQEP-----HDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGK 690
T A + EP P F+++ ++ G V C + G P P+V W +DGK
Sbjct: 5105 ETPAPVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGK 5164
Query: 691 ALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSS 746
L +D + + L++ V P G Y L +N +G S + L + +S
Sbjct: 5165 LLEEDDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTS 5220
Score = 80.1 bits (196), Expect = 2e-14
Identities = 162/747 (21%), Positives = 264/747 (35%), Gaps = 127/747 (17%)
Query: 60 PEPQVTWHRNGQPITSGGRFLLDC-GIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVT 118
P P++ W RN + G + G R LV+H V DRG + CE + ++T
Sbjct: 2014 PWPELRWTRNATALAPGKNVEIHAEGAR--HRLVLHNVGFADRGFFGCETPDDKTQAKLT 2071
Query: 119 VELT-----------------------------VEGSFAKQ-------------LGQPVV 136
VE+ V+GS+ + + P+
Sbjct: 2072 VEMRQVRLVRGLQAVEAREQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMH 2131
Query: 137 SKTLGDR---------FSAPAVETRPS-IWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
+ TL F A V T + E P F+ L VV E + C+++
Sbjct: 2132 TLTLSGLRPEDSGLMVFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECELS- 2190
Query: 187 RPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSA 246
RP V WLK V L+ ++++ + + L I+ D GVY C + A SA
Sbjct: 2191 RPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSA 2246
Query: 247 ELSIQGL------------DSANRSFVRETKATNSDVRKE---VTNVISKESKLDSLEAA 291
+ +QG D+ FV E + + +R + VT V K+ ++E
Sbjct: 2247 SVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRVKELPVTLVRPLRDKI-AMEKH 2305
Query: 292 AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSP-RTAPQTPVLQKTSSSITLQAA 350
C + W SQ P K E D R + V + + T A
Sbjct: 2306 RGVLECQVSRASAQVRWFKGSQELQPGP-KYELVSDGLYRKLIISDVHAEDEDTYTCDAG 2364
Query: 351 RVQPEPR--APGLGVLSPSGEERKRPAPPRPATF------PTRQPG--LGSQDVVSKAAN 400
V+ + + G + P PA F P+ +P L + V+ N
Sbjct: 2365 DVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETSIPSVRPPKWLLGKTVLQAGGN 2424
Query: 401 RRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQ 460
+ EG + + V L V ++ + L+ E Q
Sbjct: 2425 VGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQ 2484
Query: 461 DFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEAGVAELHIQDALPEDHGTYTCLAE 517
VL C R P + W + P+ + + + E +AEL I +P D G Y C A
Sbjct: 2485 SVVLSCDFRPAP-KAVQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQA- 2542
Query: 518 NALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQV 577
G S VTV ++ + T P L D + + + + ++
Sbjct: 2543 ---GSAHSSTEVTVEAREVT-------------VTGP-----LQDAEATEEGWASFSCEL 2581
Query: 578 SGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRT 637
S + EV W NG + +G +H+L ++ + D G S+ +V T
Sbjct: 2582 S-HEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRA----SSLKVST 2636
Query: 638 QAVLTVQEPHDGTQP-WFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDT 696
A L V+ +P F+ ++A ++ + C ++ DP V W +DG L +
Sbjct: 2637 SARLEVR-----VKPVVFLKALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQL-GPS 2689
Query: 697 GHFEVLQNEDVFTLVLKKVQPWHAGQY 723
++ L LV+ V P AG Y
Sbjct: 2690 DKYDFLHTAGTRGLVVHDVSPEDAGLY 2716
Score = 79.0 bits (193), Expect = 4e-14
Identities = 62/250 (24%), Positives = 112/250 (44%), Gaps = 13/250 (5%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILS--QEGSLCS 1085
AP F +LQ+ V +G + C V+ P ++ W +GK L+ +++ Q+G
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGG-HQ 5183
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ I +P D G+Y+C+A+N G + ++ VD +T A +S S+ +
Sbjct: 5184 LIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLS 5243
Query: 1146 GTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFG-KVTGTQPITCTWMK 1204
E + T ++ PQ+++ D +V G + F KV G W K
Sbjct: 5244 SREQEGT-------ESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFK 5296
Query: 1205 FRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDP 1264
+ + S H+++ + + L I++ +E G Y + N +G+ + L +V PD
Sbjct: 5297 DGQPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARL-LVRGPDE 5355
Query: 1265 PAGTPCASDI 1274
P P ASD+
Sbjct: 5356 PEEKP-ASDV 5364
Score = 77.8 bits (190), Expect = 9e-14
Identities = 135/590 (22%), Positives = 203/590 (34%), Gaps = 68/590 (11%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
P KF L EG C+++ V W KG+ L+ R S+ + L+
Sbjct: 3713 PSKFIEGLRNEEATEGDTATLWCELS--KAAPVEWRKGHETLRDGDRHSLRQDGSRCELQ 3770
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I G+ D G Y+C+ G+ SA L+++ L + F+ + K N + R+ T V+
Sbjct: 3771 IRGLAVVDAGEYSCVC----GQERTSATLTVRALPAR---FIEDVK--NQEAREGATAVL 3821
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQ 339
E S A + + S RGG + + S D T + V
Sbjct: 3822 QCEL---SKAAPVEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVAD---TGEYSCVCG 3875
Query: 340 KTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGLGSQDVVSKAA 399
+ +S TL QP R P + S EE + PT VV
Sbjct: 3876 QERTSATLTVRAPQPVFREP---LQSLQAEEGSTATLQCELSEPTAT-------VVWSKG 3925
Query: 400 NRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCE--------GLAVMEVAPSFSSVL 451
++ G+R+ ++ Q+++ T ++ C L V F L
Sbjct: 3926 GLQLQANGRREPRLQGCTAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLREL 3985
Query: 452 KDCAVIEGQDFVLQCSVR--GTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDH 509
+ V EG L C + G V L P + + AEL ++ ED
Sbjct: 3986 QHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDA 4045
Query: 510 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGS 569
G YTC + S S V P F L L+ G
Sbjct: 4046 GDYTCDTGHTQSMASLSVRVP----------------------RPKFKTRLQSLEQETGD 4083
Query: 570 QVTMTVQVSGNPPPEVI-WLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEA 628
+ Q+S V+ WL G E+ + +G L I ++ +DTG Y C
Sbjct: 4084 IARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEYAC-- 4141
Query: 629 WNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRD 688
G +T A L V EP + VTA + V SC ++ V W
Sbjct: 4142 --VTGGQKTAASLRVTEPEVTIVRGLVD--AEVTAD--EDVEFSCEVSRAGATGVQWCLQ 4195
Query: 689 GKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQV 738
G L + +++ + TL LK V P AG L N V
Sbjct: 4196 GLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTV 4245
Score = 77.0 bits (188), Expect = 2e-13
Identities = 67/254 (26%), Positives = 100/254 (39%), Gaps = 55/254 (21%)
Query: 545 PVAPSKP--------TAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQE 596
PV P +P AP+FL L + +V DG V+ V+G P P V W +G ++E
Sbjct: 5109 PVVPPEPLPSLLTSDAAPVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEE 5168
Query: 597 SEDFHF-EQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTV------------ 643
+ + E + H L I V P D G Y C A NS G T+A L V
Sbjct: 5169 DDHYMINEDQQGGHQLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAAD 5228
Query: 644 ---------------QEPHDGTQ--------PWFISKPRSVTASLGQSVL-ISCAIAGDP 679
+GT+ P + + R + + G + + G P
Sbjct: 5229 ATESSSYFSAQGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYP 5288
Query: 680 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVS 739
P ++W +DG+ L + H + + + TL + V +GQY + N +G
Sbjct: 5289 APRLYWFKDGQPLTA-SAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAA----- 5342
Query: 740 LMLQNSSARALPRG 753
SSAR L RG
Sbjct: 5343 ----YSSARLLVRG 5352
Score = 77.0 bits (188), Expect = 2e-13
Identities = 89/350 (25%), Positives = 131/350 (37%), Gaps = 47/350 (13%)
Query: 437 GLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR-----ST 491
G +++V P F + ++ +EG+D C++ G P P+I W +G + S
Sbjct: 6100 GKILVQVPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159
Query: 492 CEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH------------------- 532
+G+ L I+ A ED G Y C N LG SA + +
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAV 6219
Query: 533 ---------EKKSSRKSEYLLPVAPSKPTAPIFLQGL----SDLKVMDGSQ--VTMTVQV 577
++ +S L P AP T + G + GSQ VT T +
Sbjct: 6220 EDTTLERADQEVTSVLKRLLGPKAPGPSTGDLTGPGPCPRGAPALQETGSQPPVTGTSEA 6279
Query: 578 SGNPP--PEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFP-EDTGTYTCEAWNSAGE 634
PP P+ + LH G E QE E Q T +P TG + +
Sbjct: 6280 PAVPPRVPQPL-LHEGPE-QEPEAIARAQEWTVPIRMEGAAWPGAGTGELLWDVHSHVVR 6337
Query: 635 VRTQAVLTVQ--EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
TQ T Q + H P V A G + I GDP P+V W +D L
Sbjct: 6338 ETTQRTYTYQAIDTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQL 6397
Query: 693 CKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLML 742
D+ Q ++LVL+ V AG Y L +N G+ C+ L++
Sbjct: 6398 V-DSTRLSQQQEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLV 6446
Score = 76.6 bits (187), Expect = 2e-13
Identities = 65/234 (27%), Positives = 97/234 (41%), Gaps = 43/234 (18%)
Query: 23 RVDSMPLTEAPAFILPP----RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
R ++M APA PP R + EG A+ V G P+P+ W ++GQ +T G R
Sbjct: 226 RREAMRAEGAPAS--PPSTGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRR 283
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
++ + F L I + DRG YTC A+N G +V + V
Sbjct: 284 HVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVR-------------- 329
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
PAV F +L + V+E + F C++ +P + W K
Sbjct: 330 -------EPAVP------------FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEE 369
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQG 252
L SA+ + E+ + L + V+ DD VY C GS AEL++QG
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTV---AELAVQG 420
Score = 76.3 bits (186), Expect = 3e-13
Identities = 151/685 (22%), Positives = 240/685 (35%), Gaps = 126/685 (18%)
Query: 37 LPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAV 96
L R L + GA+A V + +VTW+++G+ ++S + ++ T LV+
Sbjct: 895 LARRKLQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEA-TGCTRRLVVQQA 952
Query: 97 HEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIW 156
+ D G+Y+CEA G ++++ L V+ +P V
Sbjct: 953 GQADAGEYSCEA----GGQRLSFHLDVK--------EPKVVFA----------------- 983
Query: 157 GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQ 216
K V + G SC++ + Q +V W K L S +V V K +
Sbjct: 984 -----KDQVAHSEVQAEAGASATLSCEVA-QAQTEVMWYKDGKKLSSSLKVHVEAKGCRR 1037
Query: 217 VLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETK---ATNSDVRK 273
L + + D G Y+C +G + R + E K A V
Sbjct: 1038 RLVVQQAGKTDAGDYSC---------------EARGQRVSFRLHITEPKMMFAKEQSVHN 1082
Query: 274 EVTNVISKESKLDSLEAAAKS--------KNCSSPQRGGSPPWAANSQPQPPRESKLE-- 323
EV + L A A++ K SS + G + P+ K +
Sbjct: 1083 EVQAEAGASAMLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAG 1142
Query: 324 --SCK-DSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPA 380
SC+ R + + + Q+ + + A +LS + P
Sbjct: 1143 EYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQ-----PQTEV 1197
Query: 381 TFPTRQPGLGSQDVVS---KAANRRIPME--GQRDSAFPKFESKPQSQEVKENQTVKFRC 435
T+ L S V K RR+ ++ G+ D+ E+ Q V F+
Sbjct: 1198 TWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAG--------GQRVSFQL 1249
Query: 436 EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTC 492
V V + G L C V +TW +G+ + + R
Sbjct: 1250 HITEPKAVFAKEQLVHNEVRTEAGASATLSCEVAQAQT-EVTWYKDGKKLSSSSKVRIEA 1308
Query: 493 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
+ +L +Q A D G YTC A ++ + L V S+P
Sbjct: 1309 AGCMRQLVVQQAGQADAGEYTCEA-------------------GGQRLSFHLDV--SEPK 1347
Query: 553 APIFLQGLSDLKVMD--GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
A + L+ KV G+ T++ +V+ EV W +G ++ S E G
Sbjct: 1348 AVFAKEQLAHRKVQAEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRR 1406
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP---HDGTQPWFISKPRSVTASLGQ 667
L +Q+ DTG Y+CE AG R L V EP QP R V A G
Sbjct: 1407 LVVQQACQADTGEYSCE----AGGQRLSFSLDVAEPKVVFAKEQP----VHREVQAQAGA 1458
Query: 668 SVLISCAIAGDPFPTVHWLRDGKAL 692
S +SC +A V W +DGK L
Sbjct: 1459 STTLSCEVA-QAQTEVMWYKDGKKL 1482
Score = 73.6 bits (179), Expect = 2e-12
Identities = 55/208 (26%), Positives = 75/208 (36%), Gaps = 25/208 (12%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ----YARSTCEAGVAELH 500
P F L DC G+ L C V GTP P I+W +G+ +Q + G L
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
+ D G Y C A +A G S + V P F+ +
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ-------------------VPPRFVNKV 6114
Query: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFH--FEQRGTQHSLCIQEVFP 618
++G T + G P P++ W +G + F E R L I+
Sbjct: 6115 RASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASK 6174
Query: 619 EDTGTYTCEAWNSAGEVRTQAVLTVQEP 646
ED G Y CE N G R A L +Q P
Sbjct: 6175 EDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 72.8 bits (177), Expect = 3e-12
Identities = 143/661 (21%), Positives = 237/661 (35%), Gaps = 132/661 (19%)
Query: 61 EPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
+ +V W+++G+ ++ + ++ + T LV+ + G+Y+CEA G+++++
Sbjct: 1470 QTEVMWYKDGKKLSFSSKVRMEA-VGCTRRLVVQQAGQAVAGEYSCEA----GSQRLSFH 1524
Query: 121 LTV---EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQM 177
L V + FAK+ QP + V + G
Sbjct: 1525 LHVAEPKAVFAKE--QPASRE-------------------------------VQAEAGTS 1551
Query: 178 GRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVN 237
SC++ + Q +VTW K L S++V + + L + Q D G Y+C
Sbjct: 1552 ATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKA-- 1608
Query: 238 GSGKASMSAELSIQGL-----DSANRSFVRETKAT---NSDVRKEVTNV--------ISK 281
G + S ++ + A+R E A+ + +V + T V +S
Sbjct: 1609 GDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSS 1668
Query: 282 ESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES------KLESCKDSPRTAPQT 335
SK+ +EA ++ Q G + + + R S +LE + S R +
Sbjct: 1669 SSKV-RVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEP-QISERPCRRE 1726
Query: 336 PVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFPTRQPGL-GSQDV 394
P++ K I L A P A + L E R+ + T + G+Q +
Sbjct: 1727 PLVVKEHEDIILTATLATPS--AATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVL 1784
Query: 395 VSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDC 454
S + R+ EGQ FP + V EVA F +L+
Sbjct: 1785 DSAIYSCRVGAEGQD---FP-----------------------VQVEEVAAKFCRLLEPV 1818
Query: 455 AVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TCEAGVAELHIQDALPEDHGT 511
G L C + + W ++ + E V L + ED G
Sbjct: 1819 CGELGGTVTLACEL-SPACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGE 1877
Query: 512 YTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQV 571
Y C SR + S P F+ GLS + +G +
Sbjct: 1878 YVC---------------------ESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEA 1916
Query: 572 TMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNS 631
T VS + V+W +G +Q SE F Q G HSL I ++ ED G T EA +
Sbjct: 1917 TFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITVEAEGA 1975
Query: 632 AGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKA 691
+ + A L V+E F K T SV + + P+P + W R+ A
Sbjct: 1976 S----SSAALRVRE----APVLFKKKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATA 2026
Query: 692 L 692
L
Sbjct: 2027 L 2027
Score = 71.2 bits (173), Expect = 8e-12
Identities = 36/92 (39%), Positives = 51/92 (55%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F +++ EV +G FDC + G P P V WFKD + + E H+ I+ D+ G LI
Sbjct: 5126 PVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQLI 5185
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I+ V D Y C A NS+G ++ AEL V+
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVD 5217
Score = 68.6 bits (166), Expect = 5e-11
Identities = 39/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
E K P FS T D E G A R +C + D W KD + + RH ID
Sbjct: 4891 EMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLG 4950
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV---ETMEEGEGEGEEEE 1793
DG CSL+I+ + D YTC+ N G+ T +A ++V E+ E GE ++
Sbjct: 4951 DGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSSGGELDD 5005
Score = 68.2 bits (165), Expect = 7e-11
Identities = 141/678 (20%), Positives = 231/678 (34%), Gaps = 131/678 (19%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
G A+FE V W+++G + G L + LV V +D G Y+C
Sbjct: 812 GGPAQFECET-SEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSC 870
Query: 107 EATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATK 166
S F ++ +P V F+ + R
Sbjct: 871 RVGEDSV------------DFRLRVSEPKVV------FAKEQLARR-------------- 898
Query: 167 LGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQD 226
++ + G SC++ + Q +VTW K L S++V + + L + Q
Sbjct: 899 --KLQAEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQA 955
Query: 227 DVGVYTCLVVNGSGKASMSAELSIQ------GLDSANRSFVRETKATNSDVRKEVTNVIS 280
D G Y+C +G +S L ++ D S V+ ++ + EV +
Sbjct: 956 DAGEYSC----EAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVAQAQT 1011
Query: 281 -----KESKL--DSLEAAAKSKNCSS----PQRGGSPPWAANSQPQPPRES-KLESCKDS 328
K+ K SL+ ++K C Q G + + + + R S +L +
Sbjct: 1012 EVMWYKDGKKLSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPK 1071
Query: 329 PRTAPQTPVLQKT------SSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATF 382
A + V + S+ ++ + A+ Q E T+
Sbjct: 1072 MMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTE------------------------VTW 1107
Query: 383 PTRQPGLGSQDVVS---KAANRRI--PMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEG 437
L S V K RR+ P G+ D+ E+ Q V F
Sbjct: 1108 YKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAG--------GQRVSFHLHI 1159
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYA---RSTCEA 494
V SV + G +L C V P +TW +G+ + + R +
Sbjct: 1160 TEPKGVFAKEQSVHNEVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKG 1218
Query: 495 GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
L +Q D G Y+C A G S + + E K+ E L+
Sbjct: 1219 CTRRLVVQQVGKADAGEYSCEA----GGQRVSFQLHITEPKAVFAKEQLVH--------- 1265
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
++++ G+ T++ +V+ EV W +G ++ S E G L +Q
Sbjct: 1266 ------NEVRTEAGASATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQ 1318
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ D G YTCE AG R L V EP ++ R V A G +SC
Sbjct: 1319 QAGQADAGEYTCE----AGGQRLSFHLDVSEPKAVFAKEQLAH-RKVQAEAGAIATLSCE 1373
Query: 675 IAGDPFPTVHWLRDGKAL 692
+A V W +DGK L
Sbjct: 1374 VA-QAQTEVTWYKDGKKL 1390
Score = 67.4 bits (163), Expect = 1e-10
Identities = 60/243 (24%), Positives = 96/243 (39%), Gaps = 22/243 (9%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKF--IILSQEGSLCS 1085
AP F + + V EG + +C+V P + W+ +G+ L + + + G +
Sbjct: 109 APHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASA 168
Query: 1086 VSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVL 1145
+ I A P D G Y+ A+N G A + + VD A + RP +S +L
Sbjct: 169 LRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAAD--------TASRPGTSTAALL 220
Query: 1146 G--TESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWM 1203
++ + AP +PP V G+ L VTG W
Sbjct: 221 AHLQRRREAMRAEGAPASPPSTG--------TRTCTVTEGKHARLSCYVTGEPKPETVWK 272
Query: 1204 KFRKQIQES-EHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKP 1262
K + + E H+ E+++ L IL +Q G YT N +G + V L VV +P
Sbjct: 273 KDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSV-LVVVREP 331
Query: 1263 DPP 1265
P
Sbjct: 332 AVP 334
Score = 67.4 bits (163), Expect = 1e-10
Identities = 152/714 (21%), Positives = 249/714 (34%), Gaps = 121/714 (16%)
Query: 45 KEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKY 104
+EG A F+ V + V W R+G + +F + + SL I + ED G+
Sbjct: 1911 EEGGEATFQCVVSP-SDVAVVWFRDGALLQPSEKFAISQS-GASHSLTISDLVLEDAGQI 1968
Query: 105 TCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFA 164
T EA S + + V E P F
Sbjct: 1969 TVEAEGASSSAALRVR-------------------------------------EAPVLFK 1991
Query: 165 TKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVN 224
KL V+E ++T RP P++ W + L P V + + L +H V
Sbjct: 1992 KKLEPQTVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVG 2050
Query: 225 QDDVGVYTCLVVNGSGKASMSAELS----IQGLDSANRSFVRETKATNSDVRKEVTNVIS 280
D G + C + +A ++ E+ ++GL + RE +V+ +V
Sbjct: 2051 FADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVE---AREQGTATMEVQLSHADVDG 2107
Query: 281 KESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRES-----KLESCKDSPR----- 330
++ D L + C RG P P +S K E S R
Sbjct: 2108 SWTR-DGLRFQ-QGPTCHLAVRG--PMHTLTLSGLRPEDSGLMVFKAEGVHTSARLVVTE 2163
Query: 331 -----TAPQTPVLQKTSSSITLQAARVQPEPRAPGL--GVLSPSGEERKRPAPPRPATFP 383
+ P V+ +TL+ +P L GV +G+ A +
Sbjct: 2164 LPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLT 2223
Query: 384 TRQPGLGSQ-----DVVSKAANRRIPMEGQRDSAFPK---FESKPQSQEVKENQTVKFRC 435
+ Q D ++ + ++G+ + + E + Q V EN + +
Sbjct: 2224 IYRCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQ- 2282
Query: 436 EGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARS---TC 492
L V E+ + L+D +E VL+C V ++ W Q +Q
Sbjct: 2283 --LRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASA-QVRWFKGSQELQPGPKYELVS 2339
Query: 493 EAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPT 552
+ +L I D ED TYTC A G V SA V E+ +
Sbjct: 2340 DGLYRKLIISDVHAEDEDTYTCDA----GDVKTSAQFFVEEQSIT--------------- 2380
Query: 553 APIFLQGLSDLKVMDGSQVTMTVQVS--GNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS 610
++GL D+ VM+ + + S PP+ WL +Q + EQ GT H
Sbjct: 2381 ---IVRGLQDVTVMEPAPAWFECETSIPSVRPPK--WLLGKTVLQAGGNVGLEQEGTVHR 2435
Query: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSV 669
L ++ T T + G+ R+ A L V + P +++P T QSV
Sbjct: 2436 LMLRRT----CSTMTGPVHFTVGKSRSSARLVVSD-----IPVVLTRPLEPKTGRELQSV 2486
Query: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
++SC P V W +D L + F++ + L + ++ P AG Y
Sbjct: 2487 VLSCDFRPAP-KAVQWYKDDTPL-SPSEKFKMSLEGQMAELRILRLMPADAGVY 2538
Score = 65.5 bits (158), Expect = 5e-10
Identities = 149/707 (21%), Positives = 249/707 (35%), Gaps = 139/707 (19%)
Query: 60 PEPQ-VTWHRNGQPITSGGRFLLDCGIRGTFS-LVIHAVHEEDRGKYTCEATNGSGARQV 117
P P+ V W+++ P++ +F + + G + L I + D G Y C+A + + +V
Sbjct: 2494 PAPKAVQWYKDDTPLSPSEKFKMS--LEGQMAELRILRLMPADAGVYRCQAGSAHSSTEV 2551
Query: 118 TVE---LTVEG-------------SFAKQL------------GQPVVSKTLGD------- 142
TVE +TV G SF+ +L G P+ + + +
Sbjct: 2552 TVEAREVTVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRR 2611
Query: 143 ----------------RFSAPAVETRPSIWGECPPK-FATKLGRVVVKEGQMGRFSCKIT 185
R S+ V T + P F L + +E C+++
Sbjct: 2612 HTLVLKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS 2671
Query: 186 GRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245
P+ V W K V L PS + G + L +H V+ +D G+YTC V G
Sbjct: 2672 D-PEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHV----GSEETR 2726
Query: 246 AELSIQGLDSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRG-- 303
A + + L + + K + + E + S E ++ S P
Sbjct: 2727 ARVRVHDL--------------HVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTV 2772
Query: 304 GSPPWAANSQPQPPRESK---LESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPG 360
G ++S+ Q R+ + L + +P A + + +S R +P
Sbjct: 2773 GGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERP------ 2826
Query: 361 LGVLSPSGEERKRPAPPRPATFPTRQPG-----LGSQDVVSKAANRRIPMEGQRDSAFPK 415
++ P ++ P + G L + + K+ + EG +
Sbjct: 2827 AAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMAMLVIR 2886
Query: 416 FESKPQSQEVKENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 475
S + E L V E A F+ L + V E V C P
Sbjct: 2887 GASLKDAGEYTCEVEASKSTASLHVEEKANCFTEELTNLQVEEKGTAVFTCKTE-HPAAT 2945
Query: 476 ITW---LLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
+TW LL + + + E L I D TYTC +GQ A + V
Sbjct: 2946 VTWRKGLLELRASGKHQPSQEGLTLRLTISALEKADSDTYTC----DIGQAQSRAQLLVQ 3001
Query: 533 EKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIW----- 587
++ ++ L D+ V +GS T ++S V W
Sbjct: 3002 GRRVH------------------IIEDLEDVDVQEGSSATFRCRISPANYEPVHWFLDKT 3043
Query: 588 -LHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEP 646
LH NE+ E + Q G H L ++++ +D+GT E AG+ R A L V E
Sbjct: 3044 PLH-ANELNEID----AQPGGYHVLTLRQLALKDSGTIYFE----AGDQRASAALRVTE- 3093
Query: 647 HDGTQPWFISKP-RSVTASLGQSVLISCAIAGDPFPTVHWLRDGKAL 692
+P S+ T + G+ + + C + P V W +DGK L
Sbjct: 3094 ----KPSVFSRELTDATITEGEDLTLVCETSTCDIP-VCWTKDGKTL 3135
Score = 64.3 bits (155), Expect = 1e-09
Identities = 75/284 (26%), Positives = 116/284 (40%), Gaps = 43/284 (15%)
Query: 447 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQ---PIQYARSTCEAGVAELHIQD 503
F L D + E LQC V P + W +G P AG L + D
Sbjct: 2649 FLKALDDLSAEERGTLALQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHD 2707
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 563
PED G YTC +G A V VH+ L V +K L +
Sbjct: 2708 VSPEDAGLYTC----HVGSEETRARVRVHD----------LHVGITK--------RLKTM 2745
Query: 564 KVMDGSQVTMTVQVSGNPPPE-VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTG 622
+V++G + +S + +W G + S F ++G ++ L ++E P D G
Sbjct: 2746 EVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAG 2805
Query: 623 TYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKP-RSVTASLGQSVLISCAI--AGDP 679
E S + ++A L V+E +P I KP + G+ V + C + AG P
Sbjct: 2806 ----EVVFSVRGLTSKASLIVRE-----RPAAIIKPLEDQWVAPGEDVELRCELSRAGTP 2856
Query: 680 FPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
VHWL+D KA+ K + ++V+ + LV++ AG+Y
Sbjct: 2857 ---VHWLKDRKAIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEY 2896
Score = 63.9 bits (154), Expect = 1e-09
Identities = 36/106 (33%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P TI D++ G A+F+ IEG P P V W+KD + +S E SL+
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLS-QQQEGTTYSLV 6415
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
+ V D YTC A N+ G+ C AEL+V G+ E + E++
Sbjct: 6416 LRHVASKDAGVYTCLAQNTGGQVLCKAELLV---LGGDNEPDSEKQ 6458
Score = 63.5 bits (153), Expect = 2e-09
Identities = 25/92 (27%), Positives = 49/92 (53%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + + D G + C++ G P P + W+KD ++++ H + D DG+C+LI
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+ + G D +Y C A ++ G + +++V+
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQ 6105
Score = 62.0 bits (149), Expect = 5e-09
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQ-IDYDEDGNC 1745
V P F +R VEG A+F C IEG P P++ W+KD + FQ + G
Sbjct: 6106 VPPRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLL 6165
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1781
L+I +D Y C+ VN LG A +AEL +++
Sbjct: 6166 VLVIRAASKEDLGLYECELVNRLGSARASAELRIQS 6201
Score = 60.5 bits (145), Expect = 1e-08
Identities = 56/262 (21%), Positives = 103/262 (39%), Gaps = 39/262 (14%)
Query: 1010 RGHAGTTDNE--KRSESQGTAPAFKQKLQDVHVAEGKKLL-LQCQVSSDPPATIIWTLNG 1066
+G+ + + E + + +G P ++L+D+ VA G +L Q +V P + W +G
Sbjct: 5239 QGYLSSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDG 5298
Query: 1067 KTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASEN 1126
+ L + I ++ + L ++ I ED G Y N G A S ++ V
Sbjct: 5299 QPLTASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLV-------- 5350
Query: 1127 TKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESV 1186
+ P+ +P S + L +PP++++ +KV+ G S+
Sbjct: 5351 -RGPDEPEEKPASDVHEQL---------------------VPPRMLERFTPKKVKKGSSI 5388
Query: 1187 ELFGKVTGTQPITCTWMKFRKQI------QESEHMKVENSENGSKLTILAARQEHCGCYT 1240
KV G T W++ + ++ V +S L +L ++H G YT
Sbjct: 5389 TFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYT 5448
Query: 1241 LLVENKLGSRQAQVNLTVVDKP 1262
+ N G +L V P
Sbjct: 5449 CIASNAAGQALCSASLHVSGLP 5470
Score = 60.5 bits (145), Expect = 1e-08
Identities = 62/237 (26%), Positives = 93/237 (39%), Gaps = 18/237 (7%)
Query: 311 NSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEE 370
++QP+PP E + P P P + L+ + A L + G +
Sbjct: 7331 SAQPEPPSPMAEEELAEFPE--PTWPWPGELGPHAGLEITEESEDVDA--LLAEAAVGRK 7386
Query: 371 RKRPAPPRPAT-FPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEV---- 425
RK +P R FP R L + R+ + S K +P+ E
Sbjct: 7387 RKWSSPSRSLFHFPGRH--LPLDEPAELGLRERVKASVEHISRILK--GRPEGLEKEGPP 7442
Query: 426 -KENQTVKFRCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 484
K+ FR GL + AP+F L D V+ GQ L C V P + TW +G P
Sbjct: 7443 RKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAP 7502
Query: 485 IQYARSTCEAGVAE----LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSS 537
++ + + + L I + ED G YTC NALG V+ + + E+ SS
Sbjct: 7503 LESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSS 7559
Score = 59.7 bits (143), Expect = 2e-08
Identities = 58/247 (23%), Positives = 88/247 (35%), Gaps = 42/247 (17%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
AP F + + V+ GK L CQ+ +P + W + + + L+Q+G L ++
Sbjct: 9 APRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLT 68
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
I D G Y C A+N G+A + + VD A
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAAC----------------------- 105
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
A P + P +VR G +V G+ +W K +
Sbjct: 106 -----------------AEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGR 148
Query: 1208 QIQESE--HMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
++ E + ++VE S L I AAR G Y + EN LG+ A L V
Sbjct: 149 RLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDSDAADT 208
Query: 1266 AGTPCAS 1272
A P S
Sbjct: 209 ASRPGTS 215
Score = 59.7 bits (143), Expect = 2e-08
Identities = 44/185 (23%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
+FL+ L DL + + + +VS +P V+W +G ++ S+ + F L +
Sbjct: 2648 VFLKALDDLSAEERGTLALQCEVS-DPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVH 2706
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+V PED G YTC G T+A + V + H G + +++ G+S C
Sbjct: 2707 DVSPEDAGLYTCH----VGSEETRARVRVHDLHVG----ITKRLKTMEVLEGESCSFECV 2758
Query: 675 I----AGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
+ A DP W GK + + F+ + + LV+++ P AG+ ++
Sbjct: 2759 LSHESASDP---AMWTVGGKTV-GSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGL 2814
Query: 731 VGECS 735
+ S
Sbjct: 2815 TSKAS 2819
Score = 59.7 bits (143), Expect = 2e-08
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Query: 1689 PYFSKTIRDLEVVEGSA-ARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
P + +RDL+V G+ A+F K++GYP P + WFKD Q + S H ++ D+ +L
Sbjct: 5260 PQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASAHIRMT-DKKILHTL 5318
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
I V +D +Y N++G A +A L+V +E E
Sbjct: 5319 EIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPE 5357
Score = 58.9 bits (141), Expect = 4e-08
Identities = 160/757 (21%), Positives = 260/757 (34%), Gaps = 131/757 (17%)
Query: 42 LCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHE--E 99
+C KE +A VR P + RN + T G L C + + HE
Sbjct: 3697 MCGKERTSAMLT--VRAMPSKFIEGLRN-EEATEGDTATLWCELSKAAPVEWRKGHETLR 3753
Query: 100 DRGKYTCEATNGSGARQVTVELTVE-GSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGE 158
D +++ Q+ V+ G ++ GQ S TL R
Sbjct: 3754 DGDRHSLRQDGSRCELQIRGLAVVDAGEYSCVCGQERTSATLTVR--------------A 3799
Query: 159 CPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVL 218
P +F + +EG C+++ V W KG+ L+ R S+ + L
Sbjct: 3800 LPARFIEDVKNQEAREGATAVLQCELS--KAAPVEWRKGSETLRGGDRYSLRQDGTRCEL 3857
Query: 219 EIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNV 278
+IHG++ D G Y+C+ G+ SA L++ +A R+ + ++
Sbjct: 3858 QIHGLSVADTGEYSCV----CGQERTSATLTV--------------RAPQPVFREPLQSL 3899
Query: 279 ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESC----------KDS 328
++E +L+ + G AN + RE +L+ C ++
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGR----REPRLQGCTAELVLQDLQRED 3955
Query: 329 PRTAPQTPVLQKTSSSITLQAARV------QPEPRAPG--------LGVLSPSGEERKRP 374
T Q TS+++T+ AA V Q + G L S E RK
Sbjct: 3956 TGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGS 4015
Query: 375 APPRP-ATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKF 433
P A + Q G ++ +V R + E D ++ +
Sbjct: 4016 LQLFPCAKYQMVQDGAAAELLV-----RGVEQEDAGDYTCDTGHTQSMA----------- 4059
Query: 434 RCEGLAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRIT-WLLNGQPIQYA---R 489
L+V P F + L+ G L C + + WL G +
Sbjct: 4060 ---SLSVRVPRPKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYE 4116
Query: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
+ EL I +D G Y C+ +K+ L V
Sbjct: 4117 MRSQGATRELLIHQLEAKDTGEYACVT-------------------GGQKTAASLRVTEP 4157
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR-GTQ 608
+ T ++GL D +V V + +VS V W G +Q +E R G
Sbjct: 4158 EVT---IVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPLQSNEVTEVAVRDGRI 4214
Query: 609 HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQS 668
H+L ++ V PED GT + N A + A LTV+ P + + + V S GQ
Sbjct: 4215 HTLRLKGVTPEDAGTVSFHLGNHA----SSAQLTVRAP----EVTILEPLQDVQLSEGQD 4266
Query: 669 VLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLK 728
C ++ W G L + + ++ + L L KV AG
Sbjct: 4267 ASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDAGTVSF--- 4323
Query: 729 NRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGG 765
VG CS + L + ++ + RG E + E L GG
Sbjct: 4324 -HVGTCSSEAQLKV--TAKNTVVRGLE--NVEALEGG 4355
Score = 58.2 bits (139), Expect = 7e-08
Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Query: 643 VQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVL 702
+ +P P F+++P++ S+G+ +SC I G+P P V W +D + + F +
Sbjct: 1 MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAG-ARFRLA 59
Query: 703 QNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 749
Q+ D++ L + + +GQY +N +GE V L + +A A
Sbjct: 60 QDGDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAEAACA 106
Score = 58.2 bits (139), Expect = 7e-08
Identities = 146/727 (20%), Positives = 266/727 (36%), Gaps = 139/727 (19%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTF-SLVIHAVHEEDRGKYT 105
GA+A V + +VTW+++G+ ++S + ++ G LV+ + D G+YT
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAA--GCMRQLVVQQAGQADAGEYT 1329
Query: 106 CEATNGSGARQVTVELTV---EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPK 162
CEA G ++++ L V + FAK+ L R
Sbjct: 1330 CEA----GGQRLSFHLDVSEPKAVFAKE--------QLAHR------------------- 1358
Query: 163 FATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHG 222
+V + G + SC++ + Q +VTW K L S++V + + L +
Sbjct: 1359 ------KVQAEAGAIATLSCEVA-QAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQ 1411
Query: 223 VNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFV-RETKAT-------NSDVRKE 274
Q D G Y+C G + S S +++ + A V RE +A + +V +
Sbjct: 1412 ACQADTGEYSCEA--GGQRLSFSLDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVAQA 1469
Query: 275 VTNV--------ISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR-------- 318
T V +S SK+ +EA ++ Q G + + + R
Sbjct: 1470 QTEVMWYKDGKKLSFSSKV-RMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVA 1528
Query: 319 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPR 378
E K K+ P + + TS++++ + A+ Q E G S + + A
Sbjct: 1529 EPKAVFAKEQPASR-EVQAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGC 1587
Query: 379 PATFPTRQPGLGSQDVVS-KAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEG 437
++ G S KA ++R+ +F ++P+ V F E
Sbjct: 1588 TRRLVVQEAGQADAGEYSCKAGDQRL--------SFHLHVAEPK---------VVFAKEQ 1630
Query: 438 LAVMEV-APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGV 496
A EV A + +S C V + Q +TW +G+ + + V
Sbjct: 1631 PAHREVQAEAGASATLSCEVAQAQT-------------EVTWYKDGKKLSSSSKVRVEAV 1677
Query: 497 A---ELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTA 553
L +Q A D G Y+C A ++ + L VA +P
Sbjct: 1678 GCTRRLVVQQAGQADAGEYSCEA-------------------GGQRLSFRLHVAELEPQI 1718
Query: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
L V + + +T ++ V WL +G EI+ S+ +G H+L +
Sbjct: 1719 SERPCRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTV 1778
Query: 614 QEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISC 673
D+ Y+C + Q + F V LG +V ++C
Sbjct: 1779 HGAQVLDSAIYSCRVGAEGQDFPVQV--------EEVAAKFCRLLEPVCGELGGTVTLAC 1830
Query: 674 AIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGE 733
++ V W R G + F+++ V +L + ++ AG+Y + ++R
Sbjct: 1831 ELS-PACAEVVW-RCGNTQLRVGKRFQMVAEGPVRSLTVLGLRAEDAGEY--VCESRDDH 1886
Query: 734 CSCQVSL 740
S Q+++
Sbjct: 1887 TSAQLTV 1893
Score = 57.0 bits (136), Expect = 2e-07
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEK-NGMQVLE 219
P F +L V GQ +C+++ +P Q TW K PL+ S+RV +S Q+L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAEL 248
I V +D+GVYTC V N G + + L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 55.8 bits (133), Expect = 4e-07
Identities = 44/150 (29%), Positives = 61/150 (40%), Gaps = 9/150 (6%)
Query: 1630 NAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKP 1689
N + A +++ + S + S G+ T+ L A E + AE P P
Sbjct: 188 NPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMR-------AEGAPASPP 240
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
S R V EG AR C + G P PE VW KD Q + E R + D N L I
Sbjct: 241 --STGTRTCTVTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKI 298
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
D YTC A N +G+ + ++V
Sbjct: 299 LFCKQSDRGLYTCTASNLVGQTYSSVLVVV 328
Score = 54.7 bits (130), Expect = 8e-07
Identities = 73/317 (23%), Positives = 120/317 (37%), Gaps = 49/317 (15%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAG 495
L + + F +K+ EG VLQC + + W + ++ S + G
Sbjct: 3531 LTIRALPARFIEDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETLRDGDRYSLRQDG 3588
Query: 496 V-AELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAP 554
EL I+ D G Y+C+ GQ SA +TV LP+
Sbjct: 3589 TKCELQIRGLAMADTGEYSCVC----GQERTSAMLTVRA----------LPIK------- 3627
Query: 555 IFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQ 614
F +GL + + +G+ + ++S P E W +++ + Q G + L I+
Sbjct: 3628 -FTEGLRNEEATEGATAVLRCELSKMAPVE--WWKGHETLRDGDRHSLRQDGARCELQIR 3684
Query: 615 EVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCA 674
+ ED G Y C G+ RT A+LTV+ FI R+ A+ G + + C
Sbjct: 3685 GLVAEDAGEYLC----MCGKERTSAMLTVR----AMPSKFIEGLRNEEATEGDTATLWCE 3736
Query: 675 IAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGEC 734
++ V W R G +D + Q+ L ++ + AG+Y C
Sbjct: 3737 LS--KAAPVEW-RKGHETLRDGDRHSLRQDGSRCELQIRGLAVVDAGEY---------SC 3784
Query: 735 SCQVSLMLQNSSARALP 751
C + RALP
Sbjct: 3785 VCGQERTSATLTVRALP 3801
Score = 53.9 bits (128), Expect = 1e-06
Identities = 55/227 (24%), Positives = 97/227 (42%), Gaps = 16/227 (7%)
Query: 29 LTEAP-AFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRG 87
+TE P +F P +++ E E + P V W ++G + +G + +G
Sbjct: 2161 VTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVELRAGKTMAI--AAQG 2217
Query: 88 TF-SLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGD-RFS 145
SL I+ D+G Y C+A + Q + + V+G + + V+++ G+ +F
Sbjct: 2218 ACRSLTIYRCEFADQGVYVCDAHDA----QSSASVKVQGRTYTLIYRRVLAEDAGEIQFV 2273
Query: 146 APAVETRPSIW-GECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPS 204
A E+R + E P L + E G C+++ R QV W KG+ LQP
Sbjct: 2274 AENAESRAQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVS-RASAQVRWFKGSQELQPG 2332
Query: 205 ARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
+ + + L I V+ +D YTC +G SA+ ++
Sbjct: 2333 PKYELVSDGLYRKLIISDVHAEDEDTYTC----DAGDVKTSAQFFVE 2375
Score = 53.9 bits (128), Expect = 1e-06
Identities = 80/295 (27%), Positives = 113/295 (38%), Gaps = 57/295 (19%)
Query: 998 LKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPP 1057
LK + D R + R E + F + L D+ E L LQC+VS DP
Sbjct: 2616 LKSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVS-DPE 2674
Query: 1058 ATIIWTLNGKTL-KTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQV 1116
A ++W +G L + K+ L G+ V + PED GLY C G E +V
Sbjct: 2675 AHVVWRKDGVQLGPSDKYDFLHTAGTRGLV-VHDVSPEDAGLYTC----HVGSEETRARV 2729
Query: 1117 TVDDAPASENTKAPEMKSRRPKS-SLPPVLGTESDA------------------------ 1151
V D + M+ +S S VL ES +
Sbjct: 2730 RVHDLHVGITKRLKTMEVLEGESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQG 2789
Query: 1152 ----TVKKKPAPK-----------TPPKAAM-----PPQIIQFPEDQKVRAGESVELFGK 1191
V ++ AP KA++ P II+ EDQ V GE VEL +
Sbjct: 2790 RKYILVVREAAPSDAGEVVFSVRGLTSKASLIVRERPAAIIKPLEDQWVAPGEDVELRCE 2849
Query: 1192 VT--GTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVE 1244
++ GT P+ W+K RK I++S+ V + L I A + G YT VE
Sbjct: 2850 LSRAGT-PV--HWLKDRKAIRKSQKYDVVCEGTMAMLVIRGASLKDAGEYTCEVE 2901
Score = 53.1 bits (126), Expect = 2e-06
Identities = 37/113 (32%), Positives = 48/113 (42%), Gaps = 1/113 (0%)
Query: 534 KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNE 593
+K + + L S AP FL+ LSD V+ G VT+ QVS P + W +G
Sbjct: 7443 RKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAP 7502
Query: 594 IQESEDFHFEQRGTQHS-LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQE 645
++ S L I V ED G YTC N+ G V T VL E
Sbjct: 7503 LESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTVTTTGVLRKAE 7555
Score = 52.8 bits (125), Expect = 3e-06
Identities = 56/201 (27%), Positives = 85/201 (42%), Gaps = 31/201 (15%)
Query: 447 FSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYAR--STCEAGVAE-LHIQD 503
F S L EG + QC V + V + W +G +Q + + ++G + L I D
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 504 ALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDL 563
+ ED G T AE A S SA + V E PV +F + L
Sbjct: 1960 LVLEDAGQITVEAEGA----SSSAALRVREA----------PV--------LFKKKLEPQ 1997
Query: 564 KVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGT 623
V + S VT+ V+++ P PE+ W N + ++ G +H L + V D G
Sbjct: 1998 TVEERSSVTLEVELT-RPWPELRWTRNATALAPGKNVEIHAEGARHRLVLHNVGFADRGF 2056
Query: 624 YTCEAWNSAGEVRTQAVLTVQ 644
+ CE + +TQA LTV+
Sbjct: 2057 FGCE----TPDDKTQAKLTVE 2073
Score = 52.4 bits (124), Expect = 4e-06
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
Query: 1679 AVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQID 1738
A AE+ PH F + V EGS A F C++ G P P V W KD + + E ++
Sbjct: 104 ACAEQAPH----FLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR 159
Query: 1739 YDEDGNCS-LIISDVCGDDDAKYTCKAVNSLGEATCTAELIVET 1781
+E G S L I D Y +A N LG A+ A L+V++
Sbjct: 160 VEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALVVDS 203
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/92 (33%), Positives = 43/92 (46%), Gaps = 1/92 (1%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + V G A C+I G P P+V W KD Q + F++ D D L
Sbjct: 10 PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGD-LYRLT 68
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
I D+ D +Y C+A N++GEA L V+
Sbjct: 69 ILDLALGDSGQYVCRARNAIGEAFAAVGLQVD 100
Score = 51.6 bits (122), Expect = 7e-06
Identities = 74/357 (20%), Positives = 127/357 (35%), Gaps = 59/357 (16%)
Query: 1040 VAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIIL---SQEGSLCSVSIEKALPEDR 1096
V EGK L C V+ +P +W +G+ + + ++ +QE + + K DR
Sbjct: 249 VTEGKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQ--SDR 306
Query: 1097 GLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV---------- 1144
GLY C A N GQ S V V + P + + E++ + + L V
Sbjct: 307 GLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWF 366
Query: 1145 ----------------LGTESDATVKKKPA-------------PKTPPKAAMPPQII-QF 1174
GTE TV+ A +T + A+ ++ +
Sbjct: 367 KEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKL 426
Query: 1175 PEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQE 1234
P VR G++ +F W++ ++++ + + LTI E
Sbjct: 427 PRKTAVRVGDTA-MFCVELAVPVGPVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLE 485
Query: 1235 HCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRS---SSLTLSWYGSSY-DG 1290
G + G Q V PP P +++ SS+ LSW + +
Sbjct: 486 DVGQVAFMA----GDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGER 541
Query: 1291 GSAVQSYSIEIWDSANKTW---KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTS 1344
+ Y +E TW E + V D+ + ++FRV A+N +G S
Sbjct: 542 PVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS 598
Score = 50.4 bits (119), Expect = 2e-05
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 3/100 (3%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
P+ + ++DV G + + DP ++ W + L + + QEG+ S+ +
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 6416
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTV---DDAPASE 1125
+D G+Y C+A+N GQ C ++ V D+ P SE
Sbjct: 6417 RHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEPDSE 6456
Score = 49.7 bits (117), Expect = 3e-05
Identities = 44/196 (22%), Positives = 80/196 (40%), Gaps = 36/196 (18%)
Query: 40 RNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEE 99
R + + GA+A V + +VTW+++G+ ++S + ++ + T LV+ +
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEA-VGCTRRLVVQQAGQA 1691
Query: 100 DRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGEC 159
D G+Y+CEA G ++++ L V P + RP
Sbjct: 1692 DAGEYSCEA----GGQRLSFRLHVAE-------------------LEPQISERP------ 1722
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
+ +VVKE + + + VTWLK V ++ S R + + L
Sbjct: 1723 -----CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLT 1777
Query: 220 IHGVNQDDVGVYTCLV 235
+HG D +Y+C V
Sbjct: 1778 VHGAQVLDSAIYSCRV 1793
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 7/93 (7%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSS-DPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1089
F ++L D + EG+ L L C+ S+ D P + WT +GKTL+ + LS EG + I
Sbjct: 3098 FSRELTDATITEGEDLTLVCETSTCDIP--VCWTKDGKTLRGSARCQLSHEGHRAQLLIT 3155
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
A +D G YKC +AG A S V V P
Sbjct: 3156 GATLQDSGRYKC----EAGGACSSSIVRVHARP 3184
Score = 49.7 bits (117), Expect = 3e-05
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 16/125 (12%)
Query: 1023 ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQE-G 1081
+S AP F ++L D V G+ + L CQVS+ P A W+ +G L+++ +++S
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516
Query: 1082 SLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSL 1141
+ ++I + ED G+Y C +V +A + T K+ RP SS
Sbjct: 7517 NFQLLTILVVVAEDLGVYTC---------------SVSNALGTVTTTGVLRKAERPSSSP 7561
Query: 1142 PPVLG 1146
P +G
Sbjct: 7562 CPDIG 7566
Score = 48.5 bits (114), Expect = 6e-05
Identities = 63/294 (21%), Positives = 119/294 (40%), Gaps = 50/294 (17%)
Query: 438 LAVMEVAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITW------LLNGQP--IQYAR 489
L V + F+ L++ +EG +L C + + V + W L +G ++
Sbjct: 3443 LTVKALPAKFTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEG 3500
Query: 490 STCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPS 549
+ CE + L + DA G Y C+ GQ SA +T+ LP
Sbjct: 3501 TRCELQICGLAMADA-----GEYLCVC----GQERTSATLTIRA----------LPAR-- 3539
Query: 550 KPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH 609
F++ + + + +G+ + +++ P E W +++ + + Q GT+
Sbjct: 3540 ------FIEDVKNQEAREGATAVLQCELNSAAPVE--WRKGSETLRDGDRYSLRQDGTKC 3591
Query: 610 SLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSV 669
L I+ + DTG Y+C G+ RT A+LTV+ F R+ A+ G +
Sbjct: 3592 ELQIRGLAMADTGEYSC----VCGQERTSAMLTVR----ALPIKFTEGLRNEEATEGATA 3643
Query: 670 LISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQY 723
++ C ++ V W + G +D + Q+ L ++ + AG+Y
Sbjct: 3644 VLRCELS--KMAPVEWWK-GHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEY 3694
Score = 48.1 bits (113), Expect = 7e-05
Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 5/90 (5%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F K ++DLEV E +A F C++ P E WFK++ + S + I+ +E L +
Sbjct: 335 FKKRLQDLEVREKESATFLCEVP-QPSTEAAWFKEETRLWASAKYGIE-EEGTERRLTVR 392
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+V DDDA Y C+ + AEL V+
Sbjct: 393 NVSADDDAVYICETPEG---SRTVAELAVQ 419
Score = 47.8 bits (112), Expect = 1e-04
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 18/127 (14%)
Query: 1682 EEKPH-------VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRH 1734
EEKP V P + +V +GS+ F K+EG P P V W +++ E
Sbjct: 5357 EEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEA---ERGV 5413
Query: 1735 FQIDYDEDGNC--------SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1786
I D G SL++ DV YTC A N+ G+A C+A L V + + E
Sbjct: 5414 LWIGPDTPGYTVASSAQQHSLVLLDVGRQHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Query: 1787 GEGEEEE 1793
+ + +E
Sbjct: 5474 EQEKVKE 5480
Score = 47.8 bits (112), Expect = 1e-04
Identities = 26/87 (29%), Positives = 38/87 (43%)
Query: 32 APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSL 91
AP F+ + + G + +V P Q TW ++G P+ S R L+ ++ L
Sbjct: 7462 APTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLL 7521
Query: 92 VIHAVHEEDRGKYTCEATNGSGARQVT 118
I V ED G YTC +N G T
Sbjct: 7522 TILVVVAEDLGVYTCSVSNALGTVTTT 7548
Score = 47.4 bits (111), Expect = 1e-04
Identities = 56/237 (23%), Positives = 86/237 (36%), Gaps = 48/237 (20%)
Query: 35 FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGT-FSLVI 93
FI +N +EGATA + + V W + + + G R+ L GT L I
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNS--AAPVEWRKGSETLRDGDRYSLRQD--GTKCELQI 3595
Query: 94 HAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRP 153
+ D G+Y+C G + + LTV
Sbjct: 3596 RGLAMADTGEYSCVC----GQERTSAMLTVRA---------------------------- 3623
Query: 154 SIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKN 213
P KF L EG C+++ V W KG+ L+ R S+ +
Sbjct: 3624 -----LPIKFTEGLRNEEATEGATAVLRCELS--KMAPVEWWKGHETLRDGDRHSLRQDG 3676
Query: 214 GMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSD 270
L+I G+ +D G Y C+ GK SA L+++ + S +R +AT D
Sbjct: 3677 ARCELQIRGLVAEDAGEYLCM----CGKERTSAMLTVRAMPSKFIEGLRNEEATEGD 3729
Score = 47.0 bits (110), Expect = 2e-04
Identities = 28/89 (31%), Positives = 49/89 (55%), Gaps = 5/89 (5%)
Query: 1030 AFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIE 1089
+F + LQDV E +K+ L+C++S P + W +G L+ K + ++ +G+ S++I
Sbjct: 2167 SFSRPLQDVVTTEKEKVTLECELSR-PNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225
Query: 1090 KALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
+ D+G+Y C DA A+ S V V
Sbjct: 2226 RCEFADQGVYVC----DAHDAQSSASVKV 2250
Score = 46.6 bits (109), Expect = 2e-04
Identities = 54/236 (22%), Positives = 86/236 (36%), Gaps = 16/236 (6%)
Query: 951 SGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKNDVNCKR 1010
+ PL A A ++KP +P ++P ++L S + K V +
Sbjct: 4828 TSPLASKVGAPAAPSVKPQQQQEPLAAVRPPLGDLSTKDLGDPSMD------KAAVKIQA 4881
Query: 1011 GHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK 1070
G ++ + +G P F D G L L+C V+S W +G L
Sbjct: 4882 AFKGYKVRKEMKQQEG--PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELT 4939
Query: 1071 TTKFIILSQEG-SLCSVSIEKALPEDRGLYKCVAKNDAGQ-AECSCQVTVDDAPASENTK 1128
+ + Q G CS+ I D G Y C N GQ +C V +E++
Sbjct: 4940 DGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEAESSS 4999
Query: 1129 APEMKS--RRPKSSLPPVLGTESDATVKKK----PAPKTPPKAAMPPQIIQFPEDQ 1178
E+ RR L + T+S A V + A + P + P + ED+
Sbjct: 5000 GGELDDAFRRAARRLHRLFRTKSPAEVSDEELFLSADEGPAEPEEPADWQTYREDE 5055
Score = 46.6 bits (109), Expect = 2e-04
Identities = 53/231 (22%), Positives = 87/231 (37%), Gaps = 46/231 (19%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGSLCSVS 1087
P F+++L D G+ + L C+V+ P I W +GK ++ I++ C++
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENTKAPEMKSRRPKSSLPPVLGT 1147
++ D G Y C A + AG ++ V P N K R + P V G
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVPPRFVN------KVR----ASPFVEGE 6123
Query: 1148 ESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRK 1207
++ T + AP PQI + + + G KF+
Sbjct: 6124 DAQFTCTIEGAPY--------PQIRWYKDGALLTTGN-------------------KFQT 6156
Query: 1208 QIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTV 1258
+ + V L I AA +E G Y + N+LGS +A L +
Sbjct: 6157 LSEPRSGLLV--------LVIRAASKEDLGLYECELVNRLGSARASAELRI 6199
Score = 44.3 bits (103), Expect = 0.001
Identities = 28/93 (30%), Positives = 42/93 (45%), Gaps = 5/93 (5%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F++ L+D+ V EG L+C +SS A + W L+ L QEG++ + +
Sbjct: 3187 FQEALKDLEVLEGGAATLRCVLSS-VAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRN 3245
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
P+D G Y C G S +TV PA
Sbjct: 3246 LRPQDSGRYSC----SFGDQTTSATLTVTALPA 3274
Score = 43.5 bits (101), Expect = 0.002
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 149 VETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVS 208
V P + PP A + V+ + + + +++ + VTWLK L P +
Sbjct: 697 VRAAPGLTANKPPAAAAR--EVLARLHEEAQLLAELSDQAAA-VTWLKDGRTLSPGPKYE 753
Query: 209 VSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 253
V G +VL + V +DD G+Y C+ G ++ +LS+QGL
Sbjct: 754 VQASAGRRVLLVRDVARDDAGLYECVSRGG----RIAYQLSVQGL 794
Score = 43.5 bits (101), Expect = 0.002
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 5/138 (3%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKT-TKFIILSQEGS-LCSV 1086
P F K++ EG+ C + P I W +G L T KF LS+ S L +
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDD--APASENTKAPEMKSRRPKSSLPPV 1144
I A ED GLY+C N G A S ++ + A E ++ + ++L
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSPMLQAQEQCHREQLVAAVEDTTLERA 6227
Query: 1145 LGTESDATVKKKPAPKTP 1162
E + +K+ PK P
Sbjct: 6228 -DQEVTSVLKRLLGPKAP 6244
Score = 43.5 bits (101), Expect = 0.002
Identities = 26/89 (29%), Positives = 35/89 (39%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLI 1748
P F + + D VV G + C++ P + W KD + S I L
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 1749 ISDVCGDDDAKYTCKAVNSLGEATCTAEL 1777
I V +D YTC N+LG T T L
Sbjct: 7523 ILVVVAEDLGVYTCSVSNALGTVTTTGVL 7551
Score = 43.1 bits (100), Expect = 0.002
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 6/92 (6%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F + +++ EG +LQC+++S P + W +TL+ L Q+G+ C + I
Sbjct: 3540 FIEDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
D G Y CV GQ S +TV P
Sbjct: 3598 LAMADTGEYSCV----CGQERTSAMLTVRALP 3625
Score = 43.1 bits (100), Expect = 0.002
Identities = 36/155 (23%), Positives = 65/155 (41%), Gaps = 17/155 (10%)
Query: 980 PMGNAKPDENLKSASKEELKKD-------VKNDVNCKRGHAGTTDNEKRSESQGTAPA-- 1030
P+ K E L+ + L++D ++ G ++R+ + T A
Sbjct: 3566 PVEWRKGSETLRDGDRYSLRQDGTKCELQIRGLAMADTGEYSCVCGQERTSAMLTVRALP 3625
Query: 1031 --FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
F + L++ EG +L+C++S P + W +TL+ L Q+G+ C + I
Sbjct: 3626 IKFTEGLRNEEATEGATAVLRCELSKMAP--VEWWKGHETLRDGDRHSLRQDGARCELQI 3683
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
+ ED G Y C+ G+ S +TV P+
Sbjct: 3684 RGLVAEDAGEYLCM----CGKERTSAMLTVRAMPS 3714
Score = 42.7 bits (99), Expect = 0.003
Identities = 38/159 (23%), Positives = 63/159 (39%), Gaps = 15/159 (9%)
Query: 1625 WQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPLNAEKLESEEDVSQAFLEAVAEEK 1684
W K G +R R G + TG+ K E+ S + +
Sbjct: 3128 WTKDGKTLRGSARCQLSH--EGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRV----- 3180
Query: 1685 PHVKPY-FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDG 1743
H +P F + ++DLEV+EG AA C + P V W + +R + + E
Sbjct: 3181 -HARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP-VKWCYGNNVLRPGDKYSL-RQEGA 3237
Query: 1744 NCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
L++ ++ D +Y+C S G+ T +A L V +
Sbjct: 3238 MLELVVRNLRPQDSGRYSC----SFGDQTTSATLTVTAL 3272
Score = 42.4 bits (98), Expect = 0.004
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F KL++ EG L+C++S P + W +TL+ L Q+G++C + I
Sbjct: 3276 FIGKLRNKEATEGATATLRCELSKAAP--VEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
D Y CV G+ S +T+ PA
Sbjct: 3334 LAMVDAAEYSCV----CGEERTSASLTIRPMPA 3362
Score = 42.4 bits (98), Expect = 0.004
Identities = 39/155 (25%), Positives = 62/155 (40%), Gaps = 17/155 (10%)
Query: 980 PMGNAKPDENLKSASKEELKKD-------VKNDVNCKRGHAGTTDNEKRSESQGTAPA-- 1030
P+ K E+L+ + L++D + G E+R+ + T A
Sbjct: 3390 PVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCVCGEERTSATLTVKALP 3449
Query: 1031 --FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSI 1088
F + L++ EG +L C++S P + W + L+ IL QEG+ C + I
Sbjct: 3450 AKFTEGLRNEEAVEGATAMLWCELSKVAP--VEWRKGPENLRDGDRYILRQEGTRCELQI 3507
Query: 1089 EKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
D G Y CV GQ S +T+ PA
Sbjct: 3508 CGLAMADAGEYLCV----CGQERTSATLTIRALPA 3538
Score = 38.9 bits (89), Expect = 0.045
Identities = 23/78 (29%), Positives = 39/78 (50%), Gaps = 5/78 (6%)
Query: 1042 EGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKC 1101
E + ++L C P A + W + L ++ +S EG + + I + +P D G+Y+C
Sbjct: 2482 ELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRC 2540
Query: 1102 VAKNDAGQAECSCQVTVD 1119
AG A S +VTV+
Sbjct: 2541 ----QAGSAHSSTEVTVE 2554
Score = 37.7 bits (86), Expect = 0.10
Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 6/108 (5%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
P +F + +EG C++ V W KG+ L+ R S+ + L+
Sbjct: 3537 PARFIEDVKNQEAREGATAVLQCELNSAAP--VEWRKGSETLRDGDRYSLRQDGTKCELQ 3594
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKAT 267
I G+ D G Y+C+ G+ SA L+++ L +R +AT
Sbjct: 3595 IRGLAMADTGEYSCV----CGQERTSAMLTVRALPIKFTEGLRNEEAT 3638
Score = 37.4 bits (85), Expect = 0.13
Identities = 46/236 (19%), Positives = 84/236 (35%), Gaps = 49/236 (20%)
Query: 1005 DVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTL 1064
+ +C+ G + + +E +G + +V G +L C+V+ P + W
Sbjct: 1143 EYSCEAGGQRVSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQ-PQTEVTWYK 1201
Query: 1065 NGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPAS 1124
+GK L ++ + + +G + +++ D G Y C +AG S Q+ +
Sbjct: 1202 DGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSC----EAGGQRVSFQLHI------ 1251
Query: 1125 ENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGE 1184
T PKA + + E + AG
Sbjct: 1252 ------------------------------------TEPKAVFAKEQLVHNE-VRTEAGA 1274
Query: 1185 SVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYT 1240
S L +V Q TW K K++ S +++E + +L + A Q G YT
Sbjct: 1275 SATLSCEVAQAQ-TEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYT 1329
Score = 37.4 bits (85), Expect = 0.13
Identities = 56/248 (22%), Positives = 89/248 (35%), Gaps = 47/248 (18%)
Query: 20 DPSRVDSMPLTEAPA-FILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGR 78
D + ++ +T PA FI RN EGATA R V W + + + G R
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATL--RCELSKAAPVEWRKGSETLRDGDR 3317
Query: 79 FLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSK 138
+ L L I + D +Y+C G + + LT+
Sbjct: 3318 YCLRQD-GAMCELQIRGLAMVDAAEYSCVC----GEERTSASLTI--------------- 3357
Query: 139 TLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGN 198
RP P F +L EG C+++ V W KG
Sbjct: 3358 -------------RPM-----PAHFIGRLRHQESIEGATATLRCELS--KAAPVEWRKGR 3397
Query: 199 VPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258
L+ R S+ + + L+I G+ D G Y+C+ G+ SA L+++ L +
Sbjct: 3398 ESLRDGDRHSLRQDGAVCELQICGLAVADAGEYSCV----CGEERTSATLTVKALPAKFT 3453
Query: 259 SFVRETKA 266
+R +A
Sbjct: 3454 EGLRNEEA 3461
Score = 37.4 bits (85), Expect = 0.13
Identities = 37/137 (27%), Positives = 55/137 (40%), Gaps = 21/137 (15%)
Query: 295 KNCSSPQRGGSPPWAANSQPQPPRESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQP 354
K S+PQ G SP A P PP SCK++P P +P L + +
Sbjct: 7038 KQGSAPQEGCSPHPAV--APCPPGSFPPGSCKEAP-LVPSSPFLGQPQA----------- 7083
Query: 355 EPRAPGLGVLSPSGEERKRPA----PPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRD 410
P AP SP + + P P RP P PG SQ S+ ++ R+
Sbjct: 7084 -PPAPAKA--SPPLDSKMGPGDISLPGRPKPGPCSSPGSASQASSSQVSSLRVGSSQVGT 7140
Query: 411 SAFPKFESKPQSQEVKE 427
P +++ +QE ++
Sbjct: 7141 EPGPSLDAEGWTQEAED 7157
Score = 37.0 bits (84), Expect = 0.17
Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
+P F + ++ L+ EGS A C++ P VVW K ++ + + + L
Sbjct: 3889 QPVFREPLQSLQAEEGSTATLQCEL-SEPTATVVWSKGGLQLQANGRREPRL-QGCTAEL 3946
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCT 1774
++ D+ +D +YTC + AT T
Sbjct: 3947 VLQDLQREDTGEYTCTCGSQATSATLT 3973
Score = 37.0 bits (84), Expect = 0.17
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 8/96 (8%)
Query: 531 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 590
VH ++ R +E PV P +P+AP +V G V++ ++V EVIW
Sbjct: 4608 VHLPQTVRLAEPPKPVPP-QPSAP------ESRQVAAGEDVSLELEVVAEAG-EVIWHKG 4659
Query: 591 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTC 626
IQ F +G Q L I+ ED G Y C
Sbjct: 4660 MERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695
Score = 36.6 bits (83), Expect = 0.23
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 6/88 (6%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
+ +RD +E +C++ +V WFK Q ++ +++ D LIISDV
Sbjct: 2294 RPLRDKIAMEKHRGVLECQVSR-ASAQVRWFKGSQELQPGPKYELVSDGLYR-KLIISDV 2351
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAELIVE 1780
+D+ YTC A G+ +A+ VE
Sbjct: 2352 HAEDEDTYTCDA----GDVKTSAQFFVE 2375
Score = 36.6 bits (83), Expect = 0.23
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 6/93 (6%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F +L+ EG L+C++S P + W ++L+ L Q+G++C + I
Sbjct: 3364 FIGRLRHQESIEGATATLRCELSKAAP--VEWRKGRESLRDGDRHSLRQDGAVCELQICG 3421
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPA 1123
D G Y CV G+ S +TV PA
Sbjct: 3422 LAVADAGEYSCV----CGEERTSATLTVKALPA 3450
Score = 36.6 bits (83), Expect = 0.23
Identities = 23/80 (28%), Positives = 36/80 (45%)
Query: 47 GATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTC 106
G + E V + + W ++G +T G +D GT SL+I + D G YTC
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971
Query: 107 EATNGSGARQVTVELTVEGS 126
+ +N G + + V GS
Sbjct: 4972 QVSNKFGQVTHSACVVVSGS 4991
Score = 36.2 bits (82), Expect = 0.29
Identities = 33/123 (26%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 160 PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLE 219
P KF L EG C+++ V W KG L+ R + ++ L+
Sbjct: 3449 PAKFTEGLRNEEAVEGATAMLWCELS--KVAPVEWRKGPENLRDGDRYILRQEGTRCELQ 3506
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I G+ D G Y C+ G+ SA L+I+ L + F+ + K N + R+ T V+
Sbjct: 3507 ICGLAMADAGEYLCV----CGQERTSATLTIRALPA---RFIEDVK--NQEAREGATAVL 3557
Query: 280 SKE 282
E
Sbjct: 3558 QCE 3560
Score = 35.8 bits (81), Expect = 0.38
Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
F L V EG + QC VS A ++W +G L+ ++ +SQ G+ S++I
Sbjct: 1901 FMSGLSTVVAEEGGEATFQCVVSPSDVA-VVWFRDGALLQPSEKFAISQSGASHSLTISD 1959
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1122
+ ED G A+ A S + V +AP
Sbjct: 1960 LVLEDAGQITVEAEG----ASSSAALRVREAP 1987
Score = 35.4 bits (80), Expect = 0.50
Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 1177 DQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGS-KLTILAARQEH 1235
D + + G+++ L V + W+K ++ + H ++ +G+ L I +
Sbjct: 4906 DTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRAD 4965
Query: 1236 CGCYTLLVENKLG 1248
GCYT V NK G
Sbjct: 4966 AGCYTCQVSNKFG 4978
Score = 35.4 bits (80), Expect = 0.50
Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 20/125 (16%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF--EVLQNEDVFT 709
P F+ + T LGQSV ++C ++ P W +DG L + L+N + T
Sbjct: 7463 PTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLT 7522
Query: 710 LVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQN-SSARALPRGREPAS--CEDLCGGG 766
++ +++ +G +C VS L ++ L + P+S C D+ G
Sbjct: 7523 IL-------------VVVAEDLGVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDI--GE 7567
Query: 767 VGADG 771
V ADG
Sbjct: 7568 VYADG 7572
Score = 35.0 bits (79), Expect = 0.66
Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
Query: 1667 ESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDD 1726
ES +D + A L P V + S + + EG A F C + D VVWF+D
Sbjct: 1881 ESRDDHTSAQLTVSV---PRVVKFMSG-LSTVVAEEGGEATFQCVVSP-SDVAVVWFRDG 1935
Query: 1727 QSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEA 1771
++ S F I + SL ISD+ +D + T +A + A
Sbjct: 1936 ALLQPSEKFAIS-QSGASHSLTISDLVLEDAGQITVEAEGASSSA 1979
Score = 35.0 bits (79), Expect = 0.66
Identities = 22/86 (25%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 1031 FKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEK 1090
FK+KL+ V E + L+ +++ P + WT N L K + + EG+ + +
Sbjct: 1990 FKKKLEPQTVEERSSVTLEVELTRPWPE-LRWTRNATALAPGKNVEIHAEGARHRLVLHN 2048
Query: 1091 ALPEDRGLYKCVAKNDAGQAECSCQV 1116
DRG + C +D QA+ + ++
Sbjct: 2049 VGFADRGFFGCETPDDKTQAKLTVEM 2074
Score = 35.0 bits (79), Expect = 0.66
Identities = 22/100 (22%), Positives = 39/100 (39%)
Query: 1166 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSK 1225
A PP + ED + + G + + + G + TW K Q+ +S + +
Sbjct: 6354 ARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYS 6413
Query: 1226 LTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPP 1265
L + + G YT L +N G + L V+ + P
Sbjct: 6414 LVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP 6453
Score = 34.3 bits (77), Expect = 1.1
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 7/105 (6%)
Query: 1690 YFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLII 1749
+F +R E +EG+ A C++ E W K +S+R+ + D C L I
Sbjct: 3363 HFIGRLRHQESIEGATATLRCELSKAAPVE--WRKGRESLRDGDRHSLRQD-GAVCELQI 3419
Query: 1750 SDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
+ D +Y+C GE +A L V+ + EG EE
Sbjct: 3420 CGLAVADAGEYSCVC----GEERTSATLTVKALPAKFTEGLRNEE 3460
Score = 34.3 bits (77), Expect = 1.1
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 9/102 (8%)
Query: 1681 AEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEV---VWFKDDQSIRESRHFQI 1737
A+ K K + + ++E +EG A F+C++ PEV W DD+ + S + ++
Sbjct: 4332 AQLKVTAKNTVVRGLENVEALEGGEALFECQLS---QPEVAAHTWLLDDEPVHTSENAEV 4388
Query: 1738 DYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIV 1779
+ E+G L++ D +C+ G+ +A L V
Sbjct: 4389 VFFENGLRHLLLLKNLRPQD---SCRVTFLAGDMVTSAFLTV 4427
Score = 34.3 bits (77), Expect = 1.1
Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 12/106 (11%)
Query: 1029 PAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTL-------KTTKFIILS--Q 1079
P ++ V +G + +V P T+ W T + + S Q
Sbjct: 5371 PRMLERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGPDTPGYTVASSAQ 5430
Query: 1080 EGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASE 1125
+ SL + + + + +G Y C+A N AGQA CS + V P E
Sbjct: 5431 QHSLVLLDVGR---QHQGTYTCIASNAAGQALCSASLHVSGLPKVE 5473
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/98 (20%), Positives = 39/98 (39%)
Query: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
P F A +G ++ + C +A WL+DG L H + +L+
Sbjct: 4898 PMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLL 4957
Query: 712 LKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARA 749
+ + AG Y + N+ G+ + +++ S + A
Sbjct: 4958 ITGLDRADAGCYTCQVSNKFGQVTHSACVVVSGSESEA 4995
Score = 33.1 bits (74), Expect = 2.5
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLKTTKFIILSQEGSLCSVS 1087
A F + L+ V G + L C++S A ++W L+ K + EG + S++
Sbjct: 1808 AAKFCRLLEPVCGELGGTVTLACELSP-ACAEVVWRCGNTQLRVGKRFQMVAEGPVRSLT 1866
Query: 1088 IEKALPEDRGLYKCVAKNDAGQAECSCQV 1116
+ ED G Y C +++D A+ + V
Sbjct: 1867 VLGLRAEDAGEYVCESRDDHTSAQLTVSV 1895
Score = 32.7 bits (73), Expect = 3.3
Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 6/70 (8%)
Query: 1697 DLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVCG 1754
+++ G+ A C++ P EV W+KD + + S ++ E C+ L++ V
Sbjct: 1175 EVQAEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRM---EVKGCTRRLVVQQVGK 1230
Query: 1755 DDDAKYTCKA 1764
D +Y+C+A
Sbjct: 1231 ADAGEYSCEA 1240
Score = 32.7 bits (73), Expect = 3.3
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 63 QVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGS 112
+V WH+ + I GGRF + R LVI ED+G+Y C GS
Sbjct: 4653 EVIWHKGMERIQPGGRFEVVSQGRQQM-LVIKGFTAEDQGEYHCGLAQGS 4701
Score = 32.7 bits (73), Expect = 3.3
Identities = 20/62 (32%), Positives = 28/62 (45%)
Query: 1168 PPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLT 1227
PP + D GE+V+L +VTGT +W K K +Q H + +GS
Sbjct: 6013 PPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCAL 6072
Query: 1228 IL 1229
IL
Sbjct: 6073 IL 6074
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 1693 KTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDV 1752
K + D V G C++ P V W KD ++IR+S+ + + E L+I
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDV-VCEGTMAMLVIRGA 2888
Query: 1753 CGDDDAKYTCKAVNSLGEATCTAE 1776
D +YTC+ S A+ E
Sbjct: 2889 SLKDAGEYTCEVEASKSTASLHVE 2912
Score = 32.3 bits (72), Expect = 4.3
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 3/84 (3%)
Query: 1691 FSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIIS 1750
F++ +R+ E VEG+ A C++ E W K +++R+ + I E C L I
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCELSKVAPVE--WRKGPENLRDGDRY-ILRQEGTRCELQIC 3508
Query: 1751 DVCGDDDAKYTCKAVNSLGEATCT 1774
+ D +Y C AT T
Sbjct: 3509 GLAMADAGEYLCVCGQERTSATLT 3532
Score = 32.0 bits (71), Expect = 5.6
Identities = 45/163 (27%), Positives = 61/163 (37%), Gaps = 25/163 (15%)
Query: 585 VIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
V WL +G + + + + L +++V +D G Y C + G + Q L+VQ
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECV--SRGGRIAYQ--LSVQ 792
Query: 645 EPHDGTQPWFISKPRS---VTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHF-E 700
F+ K + V A G C + VHW +DG L GH E
Sbjct: 793 -----GLARFLHKDMAGSCVDAVAGGPAQFECE-TSEAHVHVHWYKDGMEL----GHSGE 842
Query: 701 VLQNEDVFT---LVLKKVQPWHAGQYEILLKNRVGECSCQVSL 740
EDV T LV V G Y RVGE S L
Sbjct: 843 RFLQEDVGTRHRLVAATVTRQDEGTYSC----RVGEDSVDFRL 881
Score = 32.0 bits (71), Expect = 5.6
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 1695 IRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCG 1754
+ D++V EGS+A F C+I V WF D + + +ID G L + +
Sbjct: 3011 LEDVDVQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLAL 3070
Query: 1755 DDDAKYTCKAVNSLGEATC---------TAELIVETMEEGE 1786
D +A + A + EL T+ EGE
Sbjct: 3071 KDSGTIYFEAGDQRASAALRVTEKPSVFSRELTDATITEGE 3111
Score = 31.2 bits (69), Expect = 9.5
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 6/64 (9%)
Query: 1703 GSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNC--SLIISDVCGDDDAKY 1760
G++A C++ EV W+KD + + S +I E C L++ D +Y
Sbjct: 1273 GASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRI---EAAGCMRQLVVQQAGQADAGEY 1328
Query: 1761 TCKA 1764
TC+A
Sbjct: 1329 TCEA 1332
Score = 31.2 bits (69), Expect = 9.5
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 1696 RDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCS--LIISDVC 1753
R+++ G++A C++ EV W+KD + + S ++ E C+ L++
Sbjct: 1634 REVQAEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRV---EAVGCTRRLVVQQAG 1689
Query: 1754 GDDDAKYTCKA 1764
D +Y+C+A
Sbjct: 1690 QADAGEYSCEA 1700
>gi|4758194 serine/threonine kinase 17B [Homo sapiens]
Length = 372
Score = 147 bits (370), Expect = 1e-34
Identities = 77/204 (37%), Positives = 131/204 (64%), Gaps = 8/204 (3%)
Query: 1389 QKVSDFYDIEER-LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMN 1445
+ ++FY + + LG GKF V + + K T + +A KF K + + I EI+++
Sbjct: 26 ENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYAAKFLKKRRRGQDCRAEILHEIAVLE 85
Query: 1446 CLHH-PKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFEL-TERECIKYMRQISEG 1503
P+++ + +E + I+++LE +GGE+F + E E+ +E + I+ ++QI EG
Sbjct: 86 LAKSCPRVINLHEVYENTSEIILILEYAAGGEIFSLCLPELAEMVSENDVIRLIKQILEG 145
Query: 1504 VEYIHKQGIVHLDLKPENIMC--VNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAP 1561
V Y+H+ IVHLDLKP+NI+ + G IK++DFG++R++ +A L+ + GTPE++AP
Sbjct: 146 VYYLHQNNIVHLDLKPQNILLSSIYPLGD-IKIVDFGMSRKIGHACELREIMGTPEYLAP 204
Query: 1562 EVINYEPIGYATDMWSIGVICYIL 1585
E++NY+PI ATDMW+IG+I Y+L
Sbjct: 205 EILNYDPITTATDMWNIGIIAYML 228
>gi|109255245 serine/threonine kinase 17a [Homo sapiens]
Length = 414
Score = 147 bits (370), Expect = 1e-34
Identities = 73/190 (38%), Positives = 126/190 (66%), Gaps = 5/190 (2%)
Query: 1401 LGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKE--KENIRQEISIMNCLH-HPKLVQCVD 1457
LG GKF V + ++K + K +A KF + + + I EI+++ +P ++ +
Sbjct: 67 LGRGKFAVVRKCIKKDSGKEFAAKFMRKRRKGQDCRMEIIHEIAVLELAQDNPWVINLHE 126
Query: 1458 AFEEKANIVMVLEIVSGGELFERII-DEDFELTERECIKYMRQISEGVEYIHKQGIVHLD 1516
+E + +++VLE +GGE+F++ + D + E++ + MRQI EGV ++H + +VHLD
Sbjct: 127 VYETASEMILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLD 186
Query: 1517 LKPENIMCVNKTGTR-IKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDM 1575
LKP+NI+ +++ IK++DFGL+R L+N+ L+ + GTPE+VAPE+++Y+PI ATDM
Sbjct: 187 LKPQNILLTSESPLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDM 246
Query: 1576 WSIGVICYIL 1585
WSIGV+ Y++
Sbjct: 247 WSIGVLTYVM 256
>gi|27901803 protein serine kinase H1 [Homo sapiens]
Length = 424
Score = 144 bits (362), Expect = 1e-33
Identities = 74/201 (36%), Positives = 124/201 (61%), Gaps = 4/201 (1%)
Query: 1388 EQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL 1447
+ +V+ YDI+ +G G F +V R+ + TR+ +A K + + +E E+ ++ +
Sbjct: 91 DPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRV 150
Query: 1448 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYI 1507
H ++Q V+ FE + + MV+E+ +GGELF+RII + TER+ + ++ + +GV Y+
Sbjct: 151 RHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKG-SFTERDATRVLQMVLDGVRYL 209
Query: 1508 HKQGIVHLDLKPENIMCVNK-TGTRIKLIDFGL--ARRLENAGSLKVLFGTPEFVAPEVI 1564
H GI H DLKPEN++ + T ++I + DFGL AR+ + +K GTPE++APEV+
Sbjct: 210 HALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVL 269
Query: 1565 NYEPIGYATDMWSIGVICYIL 1585
+P + DMW++GVI YIL
Sbjct: 270 VRKPYTNSVDMWALGVIAYIL 290
>gi|153792294 myopalladin [Homo sapiens]
Length = 1320
Score = 141 bits (356), Expect = 5e-33
Identities = 136/517 (26%), Positives = 195/517 (37%), Gaps = 44/517 (8%)
Query: 267 TNSDVRKEVTNVISKESKLDSLEAA-AKSKNCSSPQRGGSPPWAANSQPQPPRESKLESC 325
T S + + +SKES L S + KS S Q PP P P S
Sbjct: 746 TLSSTPQTIQRTVSKESLLVSHPSVQTKSPGGLSIQNEPLPPGPTEPTPPPFTFSIPSGN 805
Query: 326 KDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRP--ATFP 383
+ PR PV TS A P P + + G R P+ P A
Sbjct: 806 QFQPRCVSPIPV-SPTSRIQNPVAFLSSVLPSLPAIPPTNAMGLPRSAPSMPSQGLAKKN 864
Query: 384 TRQPGLGSQDVVSKAANRRIPMEGQR----DSAFPKFESKPQSQEVKENQTVKFRCEGLA 439
T+ P + D + + N I G++ D + E K S E + ++FR E
Sbjct: 865 TKSPQPVNDDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTP 924
Query: 440 VME---------------VAPSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQP 484
V E +AP F LK V EG C + G PVP++ W +G+
Sbjct: 925 VDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQ 984
Query: 485 IQYARSTCEA-----GVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVTVHE------ 533
I C+ G LHI+ +D G YT +A N G++SCS + V
Sbjct: 985 ISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSR 1044
Query: 534 --------KKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEV 585
+ SR E + P FLQ D+ +G + +VSG PPPE+
Sbjct: 1045 LTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPEL 1104
Query: 586 IWLHNGNEIQESEDFHFEQRGTQ-HSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ 644
WL NG + R T HSL I + D GTY C A N G+ L+V
Sbjct: 1105 TWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVV 1164
Query: 645 EPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN 704
P + K ++ G V + C + G P P +W +D + + + Q+
Sbjct: 1165 AKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQD 1224
Query: 705 EDVFT-LVLKKVQPWHAGQYEILLKNRVGECSCQVSL 740
+ L+++ + AG Y + KN G SC L
Sbjct: 1225 TTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARL 1261
Score = 93.6 bits (231), Expect = 2e-18
Identities = 191/852 (22%), Positives = 300/852 (35%), Gaps = 171/852 (20%)
Query: 554 PIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCI 613
P F Q L +V +G++V + V G PPP+V W G E++ S D H Q G HSL I
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 614 QEVFPEDTGTYTCEAWN--------------------SAGEVRTQAVLTVQEPHDGTQP- 652
E F EDTG Y+C A N S G+ + + +Q+P++ + P
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388
Query: 653 --------------WFISKPRSVT---------------------------------ASL 665
+++PR T AS
Sbjct: 389 TTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASE 448
Query: 666 GQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN--------EDVFTLVLKKVQP 717
GQ V+ C + G P P V W R+G L +D+ F +LQ E++ TLV+ +V
Sbjct: 449 GQLVVFECRVKGAPSPKVEWYREG-TLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFA 507
Query: 718 WHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLCGGGVGADGGGSDRY 777
+G + N+ G S L ++ + EDL G +
Sbjct: 508 EDSGCFTCTASNKYGTVSSIAQLHVRGN--------------EDLSNNGSLHSANSTTNL 553
Query: 778 GSL--RPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQ----EVEQLDFRDL 831
++ +P P +E+ + GVL E R + +R E ++
Sbjct: 554 AAIEPQPSPPHSEPPSVEQPPKPKLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKGSEASS 613
Query: 832 LGKKVSTKTLSEDDLKE--------IPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVD 883
V+T+ D +E P + KPK S + +++H+
Sbjct: 614 EAGVVTTRQTRPDSFQERFNGQATKTPEPSSPVKEPPPVLAKPKLDSTQLQQLHN----- 668
Query: 884 FRSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSK 943
VL ++ + P PP P F + PA SS KA SS+
Sbjct: 669 --QVLLEQHQLQNP-----PPSSPKEFPFSMTVLNSNAPPAVTTSSK----QVKA-PSSQ 716
Query: 944 PLSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVK 1003
S A+P P N A T+ P ++ P TL ++ P ++ SKE L
Sbjct: 717 TFSLARPK-YFFPSTNT-TAATVAP--SSSPVFTL----SSTPQTIQRTVSKESLLVS-H 767
Query: 1004 NDVNCKRGHAGTTDNE--KRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATII 1061
V K + NE ++ T P F + G + +C VS P +
Sbjct: 768 PSVQTKSPGGLSIQNEPLPPGPTEPTPPPF-----TFSIPSGNQFQPRC-VSPIPVSPTS 821
Query: 1062 WTLNGKTLKTTKFIILSQEGSLCSVSIEKALPE--DRGLYKCVAK-----NDAGQAECSC 1114
N ++ L ++ + ++ P +GL K K ND E
Sbjct: 822 RIQNPVAFLSSVLPSLPAIPPTNAMGLPRSAPSMPSQGLAKKNTKSPQPVNDDNIRETKN 881
Query: 1115 QVTVDDAPASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKT---------PPKA 1165
V D + + SS L E + +++ P ++ P
Sbjct: 882 AVIRDLGKKITFSDVRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGK 941
Query: 1166 AMPPQIIQFPEDQKVRAGESVELFGKVTGTQPITCTWMKFRKQI-QESEHMKVENSENGS 1224
+ P + + +V G V K+ G W K KQI + +EH K+ +G+
Sbjct: 942 CIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGT 1001
Query: 1225 -KLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSW 1283
L I + + G YT++ N G +L V P IRS L+
Sbjct: 1002 CSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLP-----------IRS---RLTS 1047
Query: 1284 YGSSYDGGSAVQ 1295
G S+ G S VQ
Sbjct: 1048 AGQSHRGRSRVQ 1059
Score = 91.3 bits (225), Expect = 8e-18
Identities = 72/245 (29%), Positives = 111/245 (45%), Gaps = 21/245 (8%)
Query: 18 SVDPSRVDSMPLTE--APAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITS 75
S D + D +P + AP F ++ + EG+ F ++ G P P+V W ++G+ I+
Sbjct: 928 SDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISK 987
Query: 76 GGRFLLDCGIR----GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG----SF 127
C +R GT SL I + +D G YT A N G + L V+ S
Sbjct: 988 RNEH---CKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSR 1044
Query: 128 AKQLGQPVVSKT-LGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITG 186
GQ ++ + +R P E P F G +V EG++ R CK++G
Sbjct: 1045 LTSAGQSHRGRSRVQERDKEPLQERF------FRPHFLQAPGDMVAHEGRLCRLDCKVSG 1098
Query: 187 RPQPQVTWLKGNVPLQPSA-RVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMS 245
P P++TWL P+ P A + + G+ L I + Q D G Y C+ N +G+ S S
Sbjct: 1099 LPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFS 1158
Query: 246 AELSI 250
ELS+
Sbjct: 1159 LELSV 1163
Score = 90.5 bits (223), Expect = 1e-17
Identities = 69/206 (33%), Positives = 86/206 (41%), Gaps = 22/206 (10%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPI----QYARSTCEAGVAELH 500
P F D EG+ L C V G P P +TWLLNGQP+ + E GV L
Sbjct: 1073 PHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLL 1132
Query: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGL 560
I D GTY C+A N GQ S S ++V VA AP+ L+ L
Sbjct: 1133 IDPLTQRDAGTYKCIATNKTGQNSFSLELSV--------------VAKEVKKAPVILEKL 1178
Query: 561 SDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEI---QESEDFHFEQRGTQHSLCIQEVF 617
+ V +G V + +V G PPP W + I +E H + G L IQ
Sbjct: 1179 QNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYA-CLLIQPAK 1237
Query: 618 PEDTGTYTCEAWNSAGEVRTQAVLTV 643
D G YT A N AG V A L +
Sbjct: 1238 KSDAGWYTLSAKNEAGIVSCTARLDI 1263
Score = 85.9 bits (211), Expect = 3e-16
Identities = 65/232 (28%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 25 DSMPLTEA---PAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPITSGGRFLL 81
D PL E P F+ P ++ EG + + +V G P P++TW NGQP+ +
Sbjct: 1062 DKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKM 1121
Query: 82 DCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEGSFAKQLGQPVVSKTLG 141
G SL+I + + D G Y C ATN +G ++EL+V K+
Sbjct: 1122 LVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKA---------- 1171
Query: 142 DRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPL 201
P KL V EG R C++ G P P W K N +
Sbjct: 1172 -------------------PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETI 1212
Query: 202 QPSARVSVS---EKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSI 250
P R +S + G L I + D G YT N +G S +A L I
Sbjct: 1213 -PCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDI 1263
Score = 85.5 bits (210), Expect = 4e-16
Identities = 73/269 (27%), Positives = 101/269 (37%), Gaps = 65/269 (24%)
Query: 445 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELH---I 501
P F+ L+ V EG L C V G P P++ W G+ ++ + LH I
Sbjct: 269 PRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTI 328
Query: 502 QDALPEDHGTYTCLAENALGQVSCSAWVTVHEKKSSRK---------------------- 539
+A ED G Y+C A N G S SA + + SS
Sbjct: 329 AEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKPNEVSSPP 388
Query: 540 --SEYLLPVAPS----------------------------KP--TAPIFLQGLSDLKVMD 567
S + P P KP AP+F + L +L +
Sbjct: 389 TTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASE 448
Query: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQH--------SLCIQEVFPE 619
G V +V G P P+V W G I++S DF Q+ + +L I EVF E
Sbjct: 449 GQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAE 508
Query: 620 DTGTYTCEAWNSAGEVRTQAVLTVQEPHD 648
D+G +TC A N G V + A L V+ D
Sbjct: 509 DSGCFTCTASNKYGTVSSIAQLHVRGNED 537
Score = 85.1 bits (209), Expect = 6e-16
Identities = 59/237 (24%), Positives = 100/237 (42%), Gaps = 32/237 (13%)
Query: 546 VAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQR 605
+ K APIF + L +V +GS VT T ++ G P P+V W +G +I + + H + R
Sbjct: 937 IPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNE-HCKMR 995
Query: 606 GTQHSLC---IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQ------------EPHDGT 650
C I+ +D G YT A N G + L VQ + H G
Sbjct: 996 REGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGR 1055
Query: 651 ----------------QPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCK 694
+P F+ P + A G+ + C ++G P P + WL +G+ +
Sbjct: 1056 SRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLP 1115
Query: 695 DTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALP 751
D H +++ V +L++ + AG Y+ + N+ G+ S + L + + P
Sbjct: 1116 DASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAP 1172
Score = 81.6 bits (200), Expect = 6e-15
Identities = 38/97 (39%), Positives = 54/97 (55%), Gaps = 1/97 (1%)
Query: 1687 VKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSI-RESRHFQIDYDEDGNC 1745
+ P F K ++ V EGS F CKI G P P+V WFKD + I + + H ++ + DG C
Sbjct: 943 IAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTC 1002
Query: 1746 SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETM 1782
SL I DDD YT A N G +C+ L+V+++
Sbjct: 1003 SLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSL 1039
Score = 80.9 bits (198), Expect = 1e-14
Identities = 98/414 (23%), Positives = 153/414 (36%), Gaps = 86/414 (20%)
Query: 28 PLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRNGQPI-TSGGRFLLDCGIR 86
PL + P F R+ + EG + + V G P PQV W+ G+ + S ++ G
Sbjct: 264 PLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAG-- 321
Query: 87 GTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVEG-SFAKQLGQP----------- 134
SL I EED G+Y+C A+N G + E+ +EG S + G P
Sbjct: 322 NLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKEEMNRIQKP 381
Query: 135 --VVSKTLGDRFSAPAV--------ETRPSIWGECP-----------------PKFATKL 167
V S PAV + R + +C P F L
Sbjct: 382 NEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKML 441
Query: 168 GRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQ--PSARV------SVSEKNGMQVLE 219
+ EGQ+ F C++ G P P+V W + ++ P R+ S++E + L
Sbjct: 442 QNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLV 501
Query: 220 IHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANRSFVRETKATNSDVRKEVTNVI 279
I V +D G +TC N G S A+L ++G N D+
Sbjct: 502 IAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRG---------------NEDL-------- 538
Query: 280 SKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPRESKLESC---KDSPRTAPQTP 336
S SL +A + N ++ + SPP + + P + KLE + PR++ +
Sbjct: 539 ---SNNGSLHSANSTTNLAAIEPQPSPPHSEPPSVEQPPKPKLEGVLVNHNEPRSSSRIG 595
Query: 337 VL-------QKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP 383
+ S + +A V P +G+ K P P P P
Sbjct: 596 LRVHFNLPEDDKGSEASSEAGVVTTRQTRPDSFQERFNGQATKTPEPSSPVKEP 649
Score = 79.3 bits (194), Expect = 3e-14
Identities = 136/598 (22%), Positives = 217/598 (36%), Gaps = 134/598 (22%)
Query: 733 ECSCQVSLMLQNSS-ARALPRGR------EPAS--CEDLCGGGVGADGGGSDRYGSLRPG 783
E S +S +L+ S A RG EP+S C G GGG D L
Sbjct: 7 EASTSISQLLRESYLAETRHRGNNERSRAEPSSNPCHFGSPSGAAEGGGGQDDLPDL--- 63
Query: 784 WPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLGKKVSTKTLSE 843
+L +E+ ++ + + AI +E+ D + + K LS
Sbjct: 64 -----SAFLSQEELDESVNLARL----------AINYDPLEKAD------ETQARKRLSP 102
Query: 844 DDLKEIPAEQMDFRANL---------------QRQVKPKTVSE-EERKVHSPQQVDF--- 884
D +K P + F N Q +P+ SE + +KV + DF
Sbjct: 103 DQMKHSP--NLSFEPNFCQDNPRSPTSSKESPQEAKRPQYCSETQSKKVFLNKAADFIEE 160
Query: 885 RSVLAKKGTSKTPVPEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKP 944
S L K +SK P A + +S L + K+ EN SS ++ L+ + SS P
Sbjct: 161 LSSLFKSHSSKRIRPR-------ACKNHKSKLESQNKVMQENSSSFSD-LSERRERSSVP 212
Query: 945 LSNAQPSGPLKPVGNAKPAETLKPMGNAKPAETLKPMGNAKPDENLKSASKEELKKDVKN 1004
+ P+ PA+T + +E + ++E K+
Sbjct: 213 I----------PI----------------PADT-------RDNEVNHALEQQEAKRREAE 239
Query: 1005 DVNCKRGHAGTTDNEKRS-----ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPAT 1059
+ TT S E G P F QKL+ V EG ++ L C V PP
Sbjct: 240 QAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQ 299
Query: 1060 IIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVD 1119
+ W GK L+ + I + Q G+L S++I +A ED G Y C A N G S ++ ++
Sbjct: 300 VRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIE 359
Query: 1120 DAPASEN-----------TKAPEMKSRRPKSS--LPP-------VLGTESDATVKKKPAP 1159
+S++ + P S P +S +PP ++ AT+++ +P
Sbjct: 360 GVSSSDSEGDPNKEEMNRIQKPNEVSSPPTTSAVIPPAVPQAQHLVAQPRVATIQQCQSP 419
Query: 1160 KTPPKAAMPPQIIQFP------EDQKVRAGESVELFGKVTGTQPITCTWMKFRKQIQESE 1213
+ II P ++ G+ V +V G W + I++S
Sbjct: 420 TNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSP 479
Query: 1214 HMKV--------ENSENGSKLTILAARQEHCGCYTLLVENKLGSRQAQVNLTVVDKPD 1263
++ E L I E GC+T NK G+ + L V D
Sbjct: 480 DFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNED 537
Score = 76.3 bits (186), Expect = 3e-13
Identities = 105/449 (23%), Positives = 168/449 (37%), Gaps = 58/449 (12%)
Query: 850 PAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPVPEKVPP--PKP 907
P+ F + Q +TVS+E V P SV K + E +PP +P
Sbjct: 739 PSSSPVFTLSSTPQTIQRTVSKESLLVSHP------SVQTKSPGGLSIQNEPLPPGPTEP 792
Query: 908 ATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNA----KPA 963
P F + + S + ++ LS+ PS P P NA + A
Sbjct: 793 TPPPFTFSIPSGNQFQPRCVSPIPVSPTSRIQNPVAFLSSVLPSLPAIPPTNAMGLPRSA 852
Query: 964 ETLKPMGNAKP-AETLKPMGNAKPDENLKSASKEELKKDVKNDVN--------------- 1007
++ G AK ++ +P+ + E + ++ KK +DV
Sbjct: 853 PSMPSQGLAKKNTKSPQPVNDDNIRETKNAVIRDLGKKITFSDVRPNQQEYKISSFEQRL 912
Query: 1008 -------CKRGHAGTTDNEKRSESQGT----APAFKQKLQDVHVAEGKKLLLQCQVSSDP 1056
+R +D+E + + T AP F ++L+ V EG + C++ P
Sbjct: 913 MNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIP 972
Query: 1057 PATIIWTLNGKTL-KTTKFIILSQEGS-LCSVSIEKALPEDRGLYKCVAKNDAGQAECSC 1114
+ W +GK + K + + +EG CS+ IE +D G Y +A N G+ CS
Sbjct: 973 VPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSG 1032
Query: 1115 QVTVDDAP-ASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQ 1173
+ V P S T A + S R +S + E D K+P + P +Q
Sbjct: 1033 HLMVQSLPIRSRLTSAGQ--SHRGRSRV-----QERD----KEPL----QERFFRPHFLQ 1077
Query: 1174 FPEDQKVRAGESVELFGKVTGTQPITCTW-MKFRKQIQESEHMKVENSENGSKLTILAAR 1232
P D G L KV+G P TW + + + ++ H + L I
Sbjct: 1078 APGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLT 1137
Query: 1233 QEHCGCYTLLVENKLGSRQAQVNLTVVDK 1261
Q G Y + NK G + L+VV K
Sbjct: 1138 QRDAGTYKCIATNKTGQNSFSLELSVVAK 1166
Score = 64.3 bits (155), Expect = 1e-09
Identities = 32/108 (29%), Positives = 57/108 (52%), Gaps = 7/108 (6%)
Query: 1689 PYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQI-------DYDE 1741
P F+K +++L EG F+C+++G P P+V W+++ I +S F+I +
Sbjct: 435 PVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEP 494
Query: 1742 DGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEG 1789
+ C+L+I++V +D +TC A N G + A+L V E+ G
Sbjct: 495 EEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSNNG 542
Score = 63.5 bits (153), Expect = 2e-09
Identities = 35/114 (30%), Positives = 60/114 (52%), Gaps = 3/114 (2%)
Query: 1682 EEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDE 1741
EE P F++ +R EV EG+ + DC + G P P+V W+ + + + S I +
Sbjct: 262 EEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHI--VQ 319
Query: 1742 DGNC-SLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEGEEEEE 1794
GN SL I++ +D +Y+C A N G + +AE+ +E + + EG+ +E
Sbjct: 320 AGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGDPNKE 373
Score = 62.8 bits (151), Expect = 3e-09
Identities = 71/278 (25%), Positives = 111/278 (39%), Gaps = 49/278 (17%)
Query: 1010 RGHAGTTDNEKRS-ESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGK- 1067
RG + + +K + + P F Q D+ EG+ L C+VS PP + W LNG+
Sbjct: 1053 RGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQP 1112
Query: 1068 TLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAPASENT 1127
L +L +E + S+ I+ D G YKC+A N GQ S +++V A E
Sbjct: 1113 VLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSV---VAKEVK 1169
Query: 1128 KAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1187
KAP + + +P + V MPP + + +D
Sbjct: 1170 KAPVILEKLQNCGVPEGHPVRLECRV-----------IGMPPPVFYWKKD---------- 1208
Query: 1188 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1247
+ I CT R++I S H +++ + L I A++ G YTL +N+
Sbjct: 1209 -------NETIPCT----RERI--SMH---QDTTGYACLLIQPAKKSDAGWYTLSAKNEA 1252
Query: 1248 GSRQAQVNLTVVDK-----PDPPAGTPCASDIRSSSLT 1280
G L + + P P + P S R SLT
Sbjct: 1253 GIVSCTARLDIYAQWHHQIPPPMSVRPSGS--RYGSLT 1288
Score = 58.9 bits (141), Expect = 4e-08
Identities = 50/167 (29%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 6 LVASSHISKTSLSVDPSR----VDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
LVA ++ P+ +D P+ AP F +NL EG FE RV+G P
Sbjct: 404 LVAQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPS 463
Query: 62 PQVTWHRNGQPITSGGRF-LLDCGIRG------TFSLVIHAVHEEDRGKYTCEATNGSGA 114
P+V W+R G I F +L R +LVI V ED G +TC A+N G
Sbjct: 464 PKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGT 523
Query: 115 RQVTVELTVEGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPP 161
+L V G+ + L + + A+E +PS PP
Sbjct: 524 VSSIAQLHVRGN--EDLSNNGSLHSANSTTNLAAIEPQPSPPHSEPP 568
Score = 56.6 bits (135), Expect = 2e-07
Identities = 30/96 (31%), Positives = 45/96 (46%)
Query: 1688 KPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSL 1747
+P+F + D+ EG R DCK+ G P PE+ W + Q + ++ E G SL
Sbjct: 1072 RPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSL 1131
Query: 1748 IISDVCGDDDAKYTCKAVNSLGEATCTAELIVETME 1783
+I + D Y C A N G+ + + EL V E
Sbjct: 1132 LIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKE 1167
Score = 53.5 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 61/127 (48%), Gaps = 13/127 (10%)
Query: 418 SKPQSQEVKENQTVKFRCEGLAVMEV--APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPR 475
++P+ +++ Q+ +GL + AP F+ +L++ + EGQ V +C V+G P P+
Sbjct: 406 AQPRVATIQQCQSPTNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPK 465
Query: 476 ITWLLNGQPIQYA----------RSTCE-AGVAELHIQDALPEDHGTYTCLAENALGQVS 524
+ W G I+ + RS E + L I + ED G +TC A N G VS
Sbjct: 466 VEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVS 525
Query: 525 CSAWVTV 531
A + V
Sbjct: 526 SIAQLHV 532
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/146 (25%), Positives = 65/146 (44%), Gaps = 2/146 (1%)
Query: 2 GDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPE 61
G K +A++ + S S++ S V + + +AP + +N + EG + E RV G P
Sbjct: 1142 GTYKCIATNKTGQNSFSLELSVV-AKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPP 1200
Query: 62 PQVTWHRNGQPIT-SGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVE 120
P W ++ + I + R + G L+I + D G YT A N +G T
Sbjct: 1201 PVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTAR 1260
Query: 121 LTVEGSFAKQLGQPVVSKTLGDRFSA 146
L + + Q+ P+ + G R+ +
Sbjct: 1261 LDIYAQWHHQIPPPMSVRPSGSRYGS 1286
Score = 52.0 bits (123), Expect = 5e-06
Identities = 33/105 (31%), Positives = 44/105 (41%), Gaps = 3/105 (2%)
Query: 157 GEC-PPKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGM 215
G+C P F +L V EG F+CKI G P P+V W K + + G
Sbjct: 940 GKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGD 999
Query: 216 QVLEIH--GVNQDDVGVYTCLVVNGSGKASMSAELSIQGLDSANR 258
+H DD G YT + N G+ S S L +Q L +R
Sbjct: 1000 GTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSR 1044
Score = 50.8 bits (120), Expect = 1e-05
Identities = 32/102 (31%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1677 LEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESR-HF 1735
L VA+E P + +++ V EG R +C++ G P P W KD+++I +R
Sbjct: 1161 LSVVAKEVKKA-PVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERI 1219
Query: 1736 QIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAEL 1777
+ D G L+I D YT A N G +CTA L
Sbjct: 1220 SMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARL 1261
Score = 50.4 bits (119), Expect = 2e-05
Identities = 33/94 (35%), Positives = 43/94 (45%), Gaps = 5/94 (5%)
Query: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCE-----AGVAE 498
AP L++C V EG L+C V G P P W + + I R G A
Sbjct: 1171 APVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYAC 1230
Query: 499 LHIQDALPEDHGTYTCLAENALGQVSCSAWVTVH 532
L IQ A D G YT A+N G VSC+A + ++
Sbjct: 1231 LLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIY 1264
Score = 40.8 bits (94), Expect = 0.012
Identities = 25/99 (25%), Positives = 43/99 (43%), Gaps = 1/99 (1%)
Query: 649 GTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVF 708
G P F K RS G V + C + G P P V W +GK L +++ ++Q ++
Sbjct: 266 GQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKEL-ENSPDIHIVQAGNLH 324
Query: 709 TLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSA 747
+L + + G+Y N G S + ++ S+
Sbjct: 325 SLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSS 363
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,037,112
Number of Sequences: 37866
Number of extensions: 4055162
Number of successful extensions: 36869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 811
Number of HSP's successfully gapped in prelim test: 747
Number of HSP's that attempted gapping in prelim test: 16048
Number of HSP's gapped (non-prelim): 13237
length of query: 1794
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1677
effective length of database: 13,817,196
effective search space: 23171437692
effective search space used: 23171437692
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.