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Search of human proteins with 116006951
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
(2459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 4976 0.0
gi|116006953 polycystin 1-like 2 isoform c [Homo sapiens] 1979 0.0
gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 539 e-152
gi|31559825 polycystin 1-like 3 [Homo sapiens] 538 e-152
gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens] 537 e-152
gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo... 536 e-151
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens] 328 5e-89
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens] 326 2e-88
gi|5174633 receptor for egg jelly-like protein precursor [Homo s... 233 2e-60
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens] 225 4e-58
gi|4505835 polycystin 2 [Homo sapiens] 219 2e-56
gi|19923084 polycystin-1L1 [Homo sapiens] 219 3e-56
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens] 204 7e-52
gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sap... 76 4e-13
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 76 4e-13
gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sap... 75 1e-12
gi|18641360 collectin sub-family member 12 [Homo sapiens] 73 3e-12
gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo... 63 4e-09
gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo... 63 4e-09
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens] 57 2e-07
gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens] 57 2e-07
gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 57 2e-07
gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens] 57 2e-07
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens] 55 7e-07
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ... 55 7e-07
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ... 55 7e-07
gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Hom... 54 1e-06
gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Hom... 54 1e-06
gi|38372935 brevican isoform 1 [Homo sapiens] 54 2e-06
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C... 53 3e-06
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 4976 bits (12908), Expect = 0.0
Identities = 2459/2459 (100%), Positives = 2459/2459 (100%)
Query: 1 MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG 60
MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG
Sbjct: 1 MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG 60
Query: 61 GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ 120
GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ
Sbjct: 61 GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ 120
Query: 121 AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ 180
AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ
Sbjct: 121 AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ 180
Query: 181 DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT 240
DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT
Sbjct: 181 DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT 240
Query: 241 QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN 300
QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN
Sbjct: 241 QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN 300
Query: 301 PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG 360
PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG
Sbjct: 301 PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG 360
Query: 361 PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP 420
PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP
Sbjct: 361 PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP 420
Query: 421 GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE 480
GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE
Sbjct: 421 GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE 480
Query: 481 ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT 540
ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT
Sbjct: 481 ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT 540
Query: 541 APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW 600
APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW
Sbjct: 541 APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW 600
Query: 601 ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE 660
ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE
Sbjct: 601 ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE 660
Query: 661 LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW 720
LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW
Sbjct: 661 LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW 720
Query: 721 PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI 780
PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI
Sbjct: 721 PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI 780
Query: 781 APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL 840
APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL
Sbjct: 781 APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL 840
Query: 841 TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK 900
TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK
Sbjct: 841 TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK 900
Query: 901 AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC 960
AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC
Sbjct: 901 AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC 960
Query: 961 RSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNR 1020
RSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNR
Sbjct: 961 RSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNR 1020
Query: 1021 PEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQ 1080
PEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQ
Sbjct: 1021 PEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQ 1080
Query: 1081 GSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSGTVGGLR 1140
GSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSGTVGGLR
Sbjct: 1081 GSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSGTVGGLR 1140
Query: 1141 VTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPEALWVNVTSGEATLGIQLHW 1200
VTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPEALWVNVTSGEATLGIQLHW
Sbjct: 1141 VTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPEALWVNVTSGEATLGIQLHW 1200
Query: 1201 RPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAPDELPTWILSPQDLRFGEGVYYLTVVPE 1260
RPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAPDELPTWILSPQDLRFGEGVYYLTVVPE
Sbjct: 1201 RPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAPDELPTWILSPQDLRFGEGVYYLTVVPE 1260
Query: 1261 SDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGS 1320
SDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGS
Sbjct: 1261 SDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGS 1320
Query: 1321 TFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTV 1380
TFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTV
Sbjct: 1321 TFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTV 1380
Query: 1381 LEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVD 1440
LEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVD
Sbjct: 1381 LEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVD 1440
Query: 1441 AFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDC 1500
AFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDC
Sbjct: 1441 AFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDC 1500
Query: 1501 VLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLL 1560
VLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLL
Sbjct: 1501 VLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSCCFSLL 1560
Query: 1561 LCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFQNTRP 1620
LCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFQNTRP
Sbjct: 1561 LCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFQNTRP 1620
Query: 1621 RVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVPSPALGWD 1680
RVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVPSPALGWD
Sbjct: 1621 RVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVPSPALGWD 1680
Query: 1681 SVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQCPKPKAA 1740
SVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQCPKPKAA
Sbjct: 1681 SVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQCPKPKAA 1740
Query: 1741 RSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQPHSHAQALRQLQTLKGGLGVQPGTW 1800
RSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQPHSHAQALRQLQTLKGGLGVQPGTW
Sbjct: 1741 RSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQPHSHAQALRQLQTLKGGLGVQPGTW 1800
Query: 1801 APAHASALQVSKPPQGLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMA 1860
APAHASALQVSKPPQGLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMA
Sbjct: 1801 APAHASALQVSKPPQGLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMA 1860
Query: 1861 VSFVESMFVTQPLKVLGFAAFFALVLKRVDDEEDTVAPLPGHLLGPDPYALFRARRNSSR 1920
VSFVESMFVTQPLKVLGFAAFFALVLKRVDDEEDTVAPLPGHLLGPDPYALFRARRNSSR
Sbjct: 1861 VSFVESMFVTQPLKVLGFAAFFALVLKRVDDEEDTVAPLPGHLLGPDPYALFRARRNSSR 1920
Query: 1921 DVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHL 1980
DVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHL
Sbjct: 1921 DVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHL 1980
Query: 1981 QHSFTRGFSGVLGFREFFKWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSC 2040
QHSFTRGFSGVLGFREFFKWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSC
Sbjct: 1981 QHSFTRGFSGVLGFREFFKWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSC 2040
Query: 2041 PLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPIWGKLTVYR 2100
PLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPIWGKLTVYR
Sbjct: 2041 PLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPIWGKLTVYR 2100
Query: 2101 GGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSA 2160
GGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSA
Sbjct: 2101 GGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSA 2160
Query: 2161 LGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKW 2220
LGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKW
Sbjct: 2161 LGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKW 2220
Query: 2221 NLLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLV 2280
NLLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLV
Sbjct: 2221 NLLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLV 2280
Query: 2281 LLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSY 2340
LLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSY
Sbjct: 2281 LLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSY 2340
Query: 2341 KTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE 2400
KTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE
Sbjct: 2341 KTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE 2400
Query: 2401 EQKYYQLSEEGEIVDLLLMKILSFLGIKSKREEPGSSREQPGSLSQTRHSRPAQALPKD 2459
EQKYYQLSEEGEIVDLLLMKILSFLGIKSKREEPGSSREQPGSLSQTRHSRPAQALPKD
Sbjct: 2401 EQKYYQLSEEGEIVDLLLMKILSFLGIKSKREEPGSSREQPGSLSQTRHSRPAQALPKD 2459
>gi|116006953 polycystin 1-like 2 isoform c [Homo sapiens]
Length = 991
Score = 1979 bits (5126), Expect = 0.0
Identities = 975/990 (98%), Positives = 976/990 (98%), Gaps = 7/990 (0%)
Query: 1 MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG 60
MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG
Sbjct: 1 MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQG 60
Query: 61 GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ 120
GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ
Sbjct: 61 GHLVFIQDEGTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQ 120
Query: 121 AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ 180
AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ
Sbjct: 121 AAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNATVHCGLGQVIQVQ 180
Query: 181 DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT 240
DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT
Sbjct: 181 DAVYGRQNPHFCTQDAGRPSDLEQGCSWANVKEEVAGQCQELQSCQVAADETYFGNLCPT 240
Query: 241 QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN 300
QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN
Sbjct: 241 QGSYLWVQYQCREALQLMVSSESFIFDNVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN 300
Query: 301 PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG 360
PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG
Sbjct: 301 PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAG 360
Query: 361 PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP 420
PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP
Sbjct: 361 PLCQAVFGDPLWIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGP 420
Query: 421 GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE 480
GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE
Sbjct: 421 GRHRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPE 480
Query: 481 ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT 540
ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT
Sbjct: 481 ELTFEVAGLNATFSHEQVSFGEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLEIGNITIT 540
Query: 541 APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW 600
APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW
Sbjct: 541 APSGLQEPSGMNAEGKSKDKGDMEVYIQPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW 600
Query: 601 ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE 660
ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE
Sbjct: 601 ALWSSCVERQLLRTDQRELVVPASCLPPPDSAVTLRLAVLRGQELENRAEQCLYVSAPWE 660
Query: 661 LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW 720
LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW
Sbjct: 661 LRPRVSCERNCRPVNASKDILLRVTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFW 720
Query: 721 PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI 780
PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI
Sbjct: 721 PRSLTLLQSNTSTLLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVISTVPPREVPACTI 780
Query: 781 APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL 840
APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL
Sbjct: 781 APEEGTVLTSFAIFCNASTALGPLEFCFCLESGSCLHCGPEPALPSVYLPLGEENNDFVL 840
Query: 841 TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK 900
TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK
Sbjct: 841 TVVISATNRAGDTQQTQAMAKVALGDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK 900
Query: 901 AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC 960
AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC
Sbjct: 901 AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTC 960
Query: 961 RSKELTPSAQ-------WEASLALQHASEA 983
RSKELTPSAQ WE + H S A
Sbjct: 961 RSKELTPSAQGSCMGDSWEGAPPAAHVSHA 990
>gi|239756622 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1732
Score = 539 bits (1388), Expect = e-152
Identities = 357/1142 (31%), Positives = 585/1142 (51%), Gaps = 72/1142 (6%)
Query: 898 LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954
LA+ SS + H + + L + +++ +V + + G+ S GL+ + ++QE E
Sbjct: 248 LAETTSSPKEEGHPNTFTSY-LQVSLQEASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306
Query: 955 LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014
L+++T + + AQ +L + SE LL + + + T F ++ +V +
Sbjct: 307 LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366
Query: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074
A + E + + L+ + L + P L + + ++ +R
Sbjct: 367 AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425
Query: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134
S SS P+A +L L V+++I +PF + ++ G
Sbjct: 426 NISSLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485
Query: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193
++G + + S + +L+ V +L E+IEI+L R+ + PT LN+++ + + VNVTS E +
Sbjct: 486 SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544
Query: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251
L + + + +TL LG+ Y PN + + L + DE TW+L+P+ L+ G G
Sbjct: 545 LIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWVLNPEHLQHGIG 604
Query: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311
YY+T V E A V + T ++ C +W+ +TW +GCQVGP+++ +T CL
Sbjct: 605 TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664
Query: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371
CNHLTFF S F V+ +N+ T +LF +NPV V+ + L YV+ V+WAR+KD
Sbjct: 665 CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724
Query: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
D KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G EPHHL DP
Sbjct: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
VFERG +D FLL+T LG L SLRLWHDNSG PSWYVS+V+V D+ + RKW+FLCN
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
WL++++GDC LD+VF ++++ F HLF F ++W SI +R + FTR+Q
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRIQ 904
Query: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
R+SCC +LLLC M+ ++MFW + A++ + W E+++ + +++++FPINL+I
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964
Query: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666
++F Q T P Q + D S +P+ ++ E K+ R +
Sbjct: 965 GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015
Query: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726
L W S DI L+ L+ ++ + GQ ++ ++
Sbjct: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060
Query: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784
AR P ++ + C YL L+ ++ L +G Q A
Sbjct: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106
Query: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834
QLQ L+ L + P P A S+ + KP GL W V WLL+ TS
Sbjct: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166
Query: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRV----- 1889
+AFFT LY L + + W+IS+ +S ++++F++QP+KV+ F ++L++ R+
Sbjct: 1167 ASAFFTALYRLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226
Query: 1890 DDEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIR 1949
++E+ T L LL ++ R+ + VY P + K LK++K F L
Sbjct: 1227 ENEQQTKRILA--LLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTG 1283
Query: 1950 EILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNL 2009
+IL + FL +L+ Y ++ + ++L++ + +F+ FS + ++F+ WAN L+ +L
Sbjct: 1284 DILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSL 1343
Query: 2010 YG 2011
YG
Sbjct: 1344 YG 1345
Score = 203 bits (517), Expect = 1e-51
Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%)
Query: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221
G FFT L+S + + + +++IY+L + YY +QG ++ ++ W +F K N
Sbjct: 1442 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1501
Query: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281
+L+ +IIL S+ L + +K L ++++ R R+ ++ ISF E ++A +++ F VL
Sbjct: 1502 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1561
Query: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341
L+TV+LW+LLR +P++ +I+ L RAW ++ GF+++IL +L Y+IA NL+FG + Y+
Sbjct: 1562 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1621
Query: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401
T F +A T+V L +GI + EEV PVLG+FLI + ++ M VV+NLF+S IL+AF +E
Sbjct: 1622 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1681
Query: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427
+K L +E ++D LL K+ + LGI
Sbjct: 1682 RK--SLKKEAALIDTLLQKLSNLLGI 1705
Score = 38.9 bits (89), Expect = 0.063
Identities = 15/50 (30%), Positives = 28/50 (56%)
Query: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88
CY+ +F +AQ +C Q G L I ++ Q ++ ++ + ++WWIG
Sbjct: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83
>gi|31559825 polycystin 1-like 3 [Homo sapiens]
Length = 1732
Score = 538 bits (1386), Expect = e-152
Identities = 357/1142 (31%), Positives = 585/1142 (51%), Gaps = 72/1142 (6%)
Query: 898 LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954
LA+ SS + H + + L + +++ +V + + G+ S GL+ + ++QE E
Sbjct: 248 LAETTSSPKEEGHPNTFTSY-LQVSLQKASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306
Query: 955 LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014
L+++T + + AQ +L + SE LL + + + T F ++ +V +
Sbjct: 307 LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366
Query: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074
A + E + + L+ + L + P L + + ++ +R
Sbjct: 367 AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425
Query: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134
+ SS P+A +L L V+++I +PF + ++ G
Sbjct: 426 NISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485
Query: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193
++G + + S + +L+ V +L E+IEI+L R+ + PT LN+++ + + VNVTS E +
Sbjct: 486 SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544
Query: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251
L + + + +TL LG+ Y PN + + L + DE TW+L+P+ L+ G G
Sbjct: 545 LIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQHGIG 604
Query: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311
YY+T V E A V + T ++ C +W+ +TW +GCQVGP+++ +T CL
Sbjct: 605 TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664
Query: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371
CNHLTFF S F V+ +N+ T +LF +NPV V+ + L YV+ V+WAR+KD
Sbjct: 665 CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724
Query: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
D KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G EPHHL DP
Sbjct: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
VFERG +D FLL+T LG L SLRLWHDNSG PSWYVS+V+V D+ + RKW+FLCN
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
WL++++GDC LD+VF ++++ F HLF F ++W SI +R + FTRVQ
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
Query: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
R+SCC +LLLC M+ ++MFW + A++ + W E+++ + +++++FPINL+I
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964
Query: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666
++F Q T P Q + D S +P+ ++ E K+ R +
Sbjct: 965 GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015
Query: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726
L W S DI L+ L+ ++ + GQ ++ ++
Sbjct: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060
Query: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784
AR P ++ + C YL L+ ++ L +G Q A
Sbjct: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106
Query: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834
QLQ L+ L + P P A S+ + KP GL W V WLL+ TS
Sbjct: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166
Query: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRV----- 1889
+AFFT LY L + + W+IS+ +S ++++F++QP+KV+ F ++L++ R+
Sbjct: 1167 ASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226
Query: 1890 DDEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIR 1949
++E+ T L LL ++ R+ + VY P + K LK++K F L
Sbjct: 1227 ENEQQTKRILA--LLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTG 1283
Query: 1950 EILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNL 2009
+IL + FL +L+ Y ++ + ++L++ + +F+ FS + ++F+ WAN L+ +L
Sbjct: 1284 DILVQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSL 1343
Query: 2010 YG 2011
YG
Sbjct: 1344 YG 1345
Score = 203 bits (517), Expect = 1e-51
Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%)
Query: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221
G FFT L+S + + + +++IY+L + YY +QG ++ ++ W +F K N
Sbjct: 1442 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1501
Query: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281
+L+ +IIL S+ L + +K L ++++ R R+ ++ ISF E ++A +++ F VL
Sbjct: 1502 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1561
Query: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341
L+TV+LW+LLR +P++ +I+ L RAW ++ GF+++IL +L Y+IA NL+FG + Y+
Sbjct: 1562 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1621
Query: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401
T F +A T+V L +GI + EEV PVLG+FLI + ++ M VV+NLF+S IL+AF +E
Sbjct: 1622 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1681
Query: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427
+K L +E ++D LL K+ + LGI
Sbjct: 1682 RK--SLKKEAALIDTLLQKLSNLLGI 1705
Score = 38.9 bits (89), Expect = 0.063
Identities = 15/50 (30%), Positives = 28/50 (56%)
Query: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88
CY+ +F +AQ +C Q G L I ++ Q ++ ++ + ++WWIG
Sbjct: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83
>gi|239745596 PREDICTED: polycystin 1-like 3 [Homo sapiens]
Length = 1731
Score = 537 bits (1383), Expect = e-152
Identities = 355/1139 (31%), Positives = 583/1139 (51%), Gaps = 67/1139 (5%)
Query: 898 LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954
LA+ SS + H + + L + +++ +V + + G+ S GL+ + ++QE E
Sbjct: 248 LAETTSSPKEEGHPNTFTSY-LQVSLQKASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306
Query: 955 LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014
L+++T + + AQ +L + SE LL + + + T F ++ +V +
Sbjct: 307 LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366
Query: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074
A + E + + L+ + L + P L + + ++ +R
Sbjct: 367 AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425
Query: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134
+ SS P+A +L L V+++I +PF + ++ G
Sbjct: 426 NISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485
Query: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193
++G + + S + +L+ V +L E+IEI+L R+ + PT LN+++ + + VNVTS E +
Sbjct: 486 SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544
Query: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251
L + + + +TL LG+ Y PN + + L + DE TW+L+P+ L+ G G
Sbjct: 545 LIVSIDPDSPLLMTLYLGFQYQPNCTHFHLNITLPKDKVWQKDEEYTWVLNPEHLQHGIG 604
Query: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311
YY+T V E A V + T ++ C +W+ +TW +GCQVGP+++ +T CL
Sbjct: 605 TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664
Query: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371
CNHLTFF S F V+ +N+ T +LF +NPV V+ + L YV+ V+WAR+KD
Sbjct: 665 CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724
Query: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
D KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G EPHHL DP
Sbjct: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
VFERG +D FLL+T LG L SLRLWHDNSG PSWYVS+V+V D+ + RKW+FLCN
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
WL++++GDC LD+VF ++++ F HLF F ++W SI +R + FTRVQ
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRVQ 904
Query: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
R+SCC +LLLC M+ ++MFW + A++ + W E+++ + +++++FPINL+I
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964
Query: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666
++F Q T P Q + D S +P+ ++ E K+ R +
Sbjct: 965 GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015
Query: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726
L W S DI L+ L+ ++ + GQ ++ ++
Sbjct: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060
Query: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784
AR P ++ + C YL L+ ++ L +G Q A
Sbjct: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106
Query: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834
QLQ L+ L + P P A S+ + KP GL W V WLL+ TS
Sbjct: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166
Query: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD--DE 1892
+AFFT LY L + + W+IS+ +S ++++F++QP+KV+ F ++L++ R+ ++
Sbjct: 1167 ASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226
Query: 1893 EDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREIL 1952
E+ LL ++ R+ + VY P + K LK++K F L +IL
Sbjct: 1227 ENEXTKRILALLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTGDIL 1285
Query: 1953 AYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYG 2011
+ FL +L+ Y ++ + ++L++ + +F+ FS + ++F+ WAN L+ +LYG
Sbjct: 1286 VQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYG 1344
Score = 203 bits (517), Expect = 1e-51
Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%)
Query: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221
G FFT L+S + + + +++IY+L + YY +QG ++ ++ W +F K N
Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
Query: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281
+L+ +IIL S+ L + +K L ++++ R R+ ++ ISF E ++A +++ F VL
Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
Query: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341
L+TV+LW+LLR +P++ +I+ L RAW ++ GF+++IL +L Y+IA NL+FG + Y+
Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
Query: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401
T F +A T+V L +GI + EEV PVLG+FLI + ++ M VV+NLF+S IL+AF +E
Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
Query: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427
+K L +E ++D LL K+ + LGI
Sbjct: 1681 RK--SLKKEAALIDTLLQKLSNLLGI 1704
Score = 38.9 bits (89), Expect = 0.063
Identities = 15/50 (30%), Positives = 28/50 (56%)
Query: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88
CY+ +F +AQ +C Q G L I ++ Q ++ ++ + ++WWIG
Sbjct: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83
>gi|239751108 PREDICTED: polycystic kidney disease 1-like 3 [Homo
sapiens]
Length = 1731
Score = 536 bits (1381), Expect = e-151
Identities = 354/1139 (31%), Positives = 583/1139 (51%), Gaps = 67/1139 (5%)
Query: 898 LAKAVSSMLNQEHESQGSGQSLSIDVRQ---KVREHVLGSLSAVTTGLEDVQRVQELAEV 954
LA+ SS + H + + L + +++ +V + + G+ S GL+ + ++QE E
Sbjct: 248 LAETTSSPKEEGHPNTFTSY-LQVSLQKASGQVIDEIAGNFSRAVHGLQALNKLQEACEF 306
Query: 955 LREVTCRSKELTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLE 1014
L+++T + + AQ +L + SE LL + + + T F ++ +V +
Sbjct: 307 LQKLTALTPRFSKPAQVNLINSLIYLSEELLRIPFQNNNSLGFKVPPTVCPFHSLNNVTK 366
Query: 1015 ASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRI 1074
A + E + + L+ + L + P L + + ++ +R
Sbjct: 367 AGEGSWLESKRHTEPVEDILEMSLVEFGNIGEAFLEQNQSPES-SVTLTSANATLLLSRQ 425
Query: 1075 QPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVSG 1134
+ SS P+A +L L V+++I +PF + ++ G
Sbjct: 426 NISTLPLSSYTLGHPAPVRLGFPSALALKELLNKHPGVNVQITGLAFNPFKDLDNRNIVG 485
Query: 1135 TVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPE-ALWVNVTSGEAT 1193
++G + + S + +L+ V +L E+IEI+L R+ + PT LN+++ + + VNVTS E +
Sbjct: 486 SIGSV-LLSANRKLLQVHDLMEDIEIMLWRNVSLETHPTSLNMSTHQLTITVNVTSLEKS 544
Query: 1194 LGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVP--MVAPDELPTWILSPQDLRFGEG 1251
L + + + +TL LG+ Y PN + + L + DE TW+L+P+ L+ G G
Sbjct: 545 LIVSIDPDSPLLMTLYLGFQYQPNCTQFHLNITLPKDKVWQKDEEYTWMLNPEHLQHGIG 604
Query: 1252 VYYLTVVPESDLEPAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCL 1311
YY+T V E A V + T ++ C +W+ +TW +GCQVGP+++ +T CL
Sbjct: 605 TYYITAVLSERQEGAQQTPSLVSVITAVTQCYYWEIHNQTWSSAGCQVGPQSTILRTQCL 664
Query: 1312 CNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQ 1371
CNHLTFF S F V+ +N+ T +LF +NPV V+ + L YV+ V+WAR+KD
Sbjct: 665 CNHLTFFASDFFVVPRTVNVEDTIKLFLRVTNNPVGVSLLASLLGFYVITVVWARKKDQA 724
Query: 1372 DQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
D KVKVTVL DNDP AQ+HYL+ VYTG+RR AAT++KV +TLYG +G EPHHL DP
Sbjct: 725 DMQKVKVTVLADNDPSAQFHYLIQVYTGYRRSAATTAKVVITLYGSEGRSEPHHLCDPQK 784
Query: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
VFERG +D FLL+T LG L SLRLWHDNSG PSWYVS+V+V D+ + RKW+FLCN
Sbjct: 785 TVFERGGLDVFLLTTWTSLGNLHSLRLWHDNSGVSPSWYVSQVIVCDMAVKRKWHFLCNC 844
Query: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
WL++++GDC LD+VF ++++ F HLF F ++W SI +R + FTR+Q
Sbjct: 845 WLAVDLGDCELDRVFIPVSKRELFSFRHLFSSMIVEKFTQDYLWLSIATRHPWNQFTRIQ 904
Query: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
R+SCC +LLLC M+ ++MFW + A++ + W E+++ + +++++FPINL+I
Sbjct: 905 RLSCCMTLLLCNMVINVMFWKINSTTAKRDEQMRPFAVAWSELLVSIHTAVILFPINLVI 964
Query: 1612 VQIF-----QNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSL 1666
++F Q T P Q + D S +P+ ++ E K+ R +
Sbjct: 965 GRLFPLIEPQETLPLFPPIQASCLSD-------ASVEPLSATMVVEE--LKETVRFLLRR 1015
Query: 1667 FKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSS 1726
L W S DI L+ L+ ++ + GQ ++ ++
Sbjct: 1016 NTYLLSKCEQPPWSS---WDITKLVKLLSSLV-SSHLEGQGCHQQGERH----------- 1060
Query: 1727 EMKEKSQCPKPKAARSGPWKDSAYRQCLYLQ--LEHVEQELRLVGPRGFSQPHSHAQALR 1784
AR P ++ + C YL L+ ++ L +G Q A
Sbjct: 1061 ------------WARVVP--ENHHHFCCYLHRVLQRLKSHLGTLGLTQGHQSCDFLDAAS 1106
Query: 1785 QLQTLKGGL--GVQPGTWAP-------AHASALQVSKP-PQGLPWWCILVGWLLVAATSG 1834
QLQ L+ L + P P A S+ + KP GL W V WLL+ TS
Sbjct: 1107 QLQKLQELLETHILPTEQEPSREVTSFAILSSEEGKKPISNGLSKWLTSVCWLLLGFTSL 1166
Query: 1835 VAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFFALVLKRVD--DE 1892
+AFFT LY L + + W+IS+ +S ++++F++QP+KV+ F ++L++ R+ ++
Sbjct: 1167 ASAFFTALYSLELSKDQATSWMISIILSVLQNIFISQPVKVVFFTFLYSLMMSRMPRLNK 1226
Query: 1893 EDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREIL 1952
E+ LL ++ R+ + VY P + K LK++K F L +IL
Sbjct: 1227 ENEXTKRILALLAKCSSSV-PGSRDKNNPVYVAPAINSPTKHPERTLKKKKLFKLTGDIL 1285
Query: 1953 AYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYG 2011
+ FL +L+ Y ++ + ++L++ + +F+ FS + ++F+ WAN L+ +LYG
Sbjct: 1286 VQILFLTLLMTAIYSAKNSNRFYLHQAIWKTFSHQFSEIKLLQDFYPWANHILLPSLYG 1344
Score = 203 bits (517), Expect = 1e-51
Identities = 102/266 (38%), Positives = 171/266 (64%), Gaps = 2/266 (0%)
Query: 2162 GTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWN 2221
G FFT L+S + + + +++IY+L + YY +QG ++ ++ W +F K N
Sbjct: 1441 GAFFTSLRLESFTSLQMSKKGCVWSIISQVIYYLLVCYYAFIQGCQLKQQKWRFFTGKRN 1500
Query: 2222 LLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVL 2281
+L+ +IIL S+ L + +K L ++++ R R+ ++ ISF E ++A +++ F VL
Sbjct: 1501 ILDTSIILISFILLGLDMKSISLHKKNMARYRDDQDRFISFYEAVKVNSAATHLVGFPVL 1560
Query: 2282 LSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYK 2341
L+TV+LW+LLR +P++ +I+ L RAW ++ GF+++IL +L Y+IA NL+FG + Y+
Sbjct: 1561 LATVQLWNLLRHSPRLRVISRTLSRAWDEVVGFLLIILILLTGYAIAFNLLFGCSISDYR 1620
Query: 2342 TLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSEE 2401
T F +A T+V L +GI + EEV PVLG+FLI + ++ M VV+NLF+S IL+AF +E
Sbjct: 1621 TFFSSAVTVVGLLMGISHQEEVFALDPVLGTFLILTSVILMVLVVINLFVSAILMAFGKE 1680
Query: 2402 QKYYQLSEEGEIVDLLLMKILSFLGI 2427
+K L +E ++D LL K+ + LGI
Sbjct: 1681 RK--SLKKEAALIDTLLQKLSNLLGI 1704
Score = 38.9 bits (89), Expect = 0.063
Identities = 15/50 (30%), Positives = 28/50 (56%)
Query: 39 CYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWIG 88
CY+ +F +AQ +C Q G L I ++ Q ++ ++ + ++WWIG
Sbjct: 34 CYQLNRFQCSFEEAQHYCHVQRGFLAHIWNKEVQDLIRDYLEEGKKWWIG 83
>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
Length = 4303
Score = 328 bits (840), Expect = 5e-89
Identities = 398/1539 (25%), Positives = 651/1539 (42%), Gaps = 200/1539 (12%)
Query: 889 EGGPEQLLQLAKAVSSMLNQ-----------EHESQGSGQSLSIDVRQKVREHVLGSLSA 937
+ P+ +++ + A+ ++LN+ +HE Q Q +R+ + E L SL
Sbjct: 2602 QADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQ-----IRKNITE-TLVSLRV 2655
Query: 938 VTTGLEDVQRVQE-LAEVL---REVTCRSKELTPSAQWEASLALQHASEALLTVSAKARP 993
T ++D+Q++ LA+ + RE+ CRS + EA + + A TV+ A
Sbjct: 2656 HT--VDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIG 2713
Query: 994 EDQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGK 1053
+ T DL S + A + E AE+ S +A+ + + + L+ +
Sbjct: 2714 DSILN--ITGDLIHLASSDVRAPQPS--ELGAESPSRMVAS--QAYNLTSALMRILMRSR 2767
Query: 1054 LPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVD 1113
+ P LA I R P S P F +P A S +L + V
Sbjct: 2768 VLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAP--GPGCHFSIPEAFS-GALANLSDVVQ 2824
Query: 1114 IKIMSFPKSPFPAR--SHFDVSGTVGGLRVTSPSGQLIPVKNLSEN--IEILLPRHSQ-- 1167
+ I +PFP S++ VS V + + +G IP++ L+ I + +P +S
Sbjct: 2825 L-IFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWA 2883
Query: 1168 ---RHSQPTVLN--LTSPEA-----LWVNVTSGEATLGIQLHW----------RPDIALT 1207
S N + P+A + ++ ++ A L +QL++ P+ L
Sbjct: 2884 ARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLA 2943
Query: 1208 LSLGYGYHPNKSSYDAQTHLVP--MVAPDELP-TWILSPQDLRFGEGVYYLTVVPESDLE 1264
+ L PN+ + A + P + D P T+ +SP R G Y+L +
Sbjct: 2944 VYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGS-RDPAGSYHLNLSSHFRWS 3002
Query: 1265 PAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLV 1324
L V + + S C ++ E W G TSP Q CL HLT FG++ V
Sbjct: 3003 A-----LQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFV 3057
Query: 1325 MSNAINI---HQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTVL 1381
+ + TA++ N +V+ T V Y+++ + D D ++ +
Sbjct: 3058 PPSHVRFVFPEPTADV------NYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAI-- 3109
Query: 1382 EDNDPFA----QYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERG 1437
PF ++ Y + V TG RG+ T++ V + LYG+D HL D D F R
Sbjct: 3110 ----PFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL-DGDR-AFHRN 3163
Query: 1438 AVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSI-- 1495
++D F ++T LG + +R+WHDN G P+W++ V+V DL R +FL N WLS+
Sbjct: 3164 SLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVET 3223
Query: 1496 NVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSC 1555
+++K A++ +F L + GF D HIW SI+ R RS FTR+QR +C
Sbjct: 3224 EANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATC 3283
Query: 1556 CFSLLLCTMLTSIMFW-GVPKDPAEQKMDLGKIE-FTWQEVMIGLESSILMFPINLLIVQ 1613
C LL+C L + W G D A + ++ + V +GL SS++++P+ L I+
Sbjct: 3284 CV-LLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILF 3342
Query: 1614 IFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVP 1673
+F+ +R +VA GSP+ TP+ Q + D ++ D S + F L
Sbjct: 3343 LFRMSRSKVA----------GSPSPTPAGQQVLDIDSCLDSSVLDSSFLT---FSGLHAE 3389
Query: 1674 SPALGWDSVNLM--DINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTLTLGSSEMKEK 1731
+G +L D SL V +P G + W + DP ++ S ++
Sbjct: 3390 QAFVGQMKSDLFLDDSKSL------VCWPSG-EGTLSWPDL--LSDP---SIVGSNLR-- 3435
Query: 1732 SQCPKPKAARS-GPWKDSAYRQCLYLQLEHV----EQELRLVGPRGFSQP------HSHA 1780
Q + +A GP +D Y + E ++ V G S P H
Sbjct: 3436 -QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMET 3494
Query: 1781 QALRQLQTLKG----GLGVQ---------PG-TWAPAHASALQVSKPPQG-----LPWWC 1821
L L + G L +Q PG W A+ L + +G LP WC
Sbjct: 3495 DLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWC 3554
Query: 1822 ILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAF 1881
+ L VA + G + S+ WL+S + SF+ S +PLKVL A +
Sbjct: 3555 ASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALY 3614
Query: 1882 FALVLKRV-DDEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLK 1940
F+LV KR+ DE+DT+ P + P + R R PP A+ K K
Sbjct: 3615 FSLVAKRLHPDEDDTLVESPA--VTPVSARVPRVR---------PPHGFALFLAKEEARK 3663
Query: 1941 EQKAFALIREILAYLGFLWMLLLVAYGQRD--PSAYHLNRHL-QHSFTRGFSGVLGFREF 1997
++ ++R +L Y+ FL + LL +YG AY L + Q +R F + E
Sbjct: 3664 VKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEEL 3723
Query: 1998 FKWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPLAQQPQAYLNGCRAPY 2057
+ W L+ ++G+ +S +G ++RQVR+QE+ P P+ + +
Sbjct: 3724 WPWMAHVLLPYVHGNQ-------SSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGF 3776
Query: 2058 SLDAEDMADYGEGWNA--TTLSEWQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQST 2115
S +DY GW + W Y + D + WG VY GGYV LG + +
Sbjct: 3777 S-----TSDYDVGWESPHNGSGTWAYSAPDLLGAWS-WGSCAVYDSGGYVQELGLSLEES 3830
Query: 2116 SRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRL 2175
LR+L + WLD +RAVF+E T Y+ V L VTL LE A G +++ L
Sbjct: 3831 RDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFAL 3890
Query: 2176 YPFTDGWH-PFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAI----ILA 2230
+ G P + + L+ LF +++ V + + +E +W +L L +L
Sbjct: 3891 RRLSAGLSLPLLTSVCLL--LFAVHFAVAEARTWHRE------GRWRVLRLGAWARWLLV 3942
Query: 2231 SWSALAVFVKRAVLAERDLQRCRNHR---EEGISFSETAAADAALGYIIAFLVLLSTVKL 2287
+ +A V+ A L D Q R R SF + A +A + A L+ L VK
Sbjct: 3943 ALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKA 4002
Query: 2288 WHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYS 2326
LR + ++ L RA ++ G + ++ + +AY+
Sbjct: 4003 AQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYA 4041
Score = 37.7 bits (86), Expect = 0.14
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 30/199 (15%)
Query: 304 VSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAGPLC 363
V NV H + +PGE+ + + + ++T Q V+VR + +++V G+
Sbjct: 1087 VEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGV--------- 1137
Query: 364 QAVFGDPL-WIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGPGR 422
V G P+ + L GV YT GD + + +Q + T G
Sbjct: 1138 -LVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAA--------NHTYASRGTYH 1188
Query: 423 HRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEEL 482
RLE+ N T S + V + E L GL S +E G ++++ ++ G
Sbjct: 1189 VRLEV----NNTVSGAAAQADVRVFEELRGLSVD-MSLAVEQGAPVVVSAAVQTGDNITW 1243
Query: 483 TFE------VAGLNATFSH 495
TF+ ++G AT H
Sbjct: 1244 TFDMGDGTVLSGPEATVEH 1262
Score = 34.7 bits (78), Expect = 1.2
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 15/126 (11%)
Query: 424 RLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEELT 483
+L + A+ + + T++ N+TV + + GLQ S L L +T + + E+
Sbjct: 993 KLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVA 1052
Query: 484 F-EVAGLNATFSHE-QVSFGEPFGICRLAV-------------PVEGTFLVTMLVRNAFS 528
F G H+ Q + E F + +V G +L+T+L NAF
Sbjct: 1053 FLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFE 1112
Query: 529 NLSLEI 534
NL+ ++
Sbjct: 1113 NLTQQV 1118
>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
Length = 4302
Score = 326 bits (836), Expect = 2e-88
Identities = 390/1538 (25%), Positives = 647/1538 (42%), Gaps = 199/1538 (12%)
Query: 889 EGGPEQLLQLAKAVSSMLNQ-----------EHESQGSGQSLSIDVRQKVREHVLGSLSA 937
+ P+ +++ + A+ ++LN+ +HE Q Q +R+ + E L SL
Sbjct: 2602 QADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQ-----IRKNITE-TLVSLRV 2655
Query: 938 VTTGLEDVQRVQE-LAEVL---REVTCRSKELTPSAQWEASLALQHASEALLTVSAKARP 993
T ++D+Q++ LA+ + RE+ CRS + EA + + A TV+ A
Sbjct: 2656 HT--VDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIG 2713
Query: 994 EDQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIATVLRLLRVMEHVQTTLLLGK 1053
+ T DL S + A + E AE+ S +A+ + + + L+ +
Sbjct: 2714 DSILN--ITGDLIHLASSDVRAPQPS--ELGAESPSRMVAS--QAYNLTSALMRILMRSR 2767
Query: 1054 LPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPDAADSATFMLPAASSLSSLEGGQEPVD 1113
+ P LA I R P S P F +P A S +L + V
Sbjct: 2768 VLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAP--GPGCHFSIPEAFS-GALANLSDVVQ 2824
Query: 1114 IKIMSFPKSPFPAR--SHFDVSGTVGGLRVTSPSGQLIPVKNLSEN--IEILLPRHSQ-- 1167
+ I +PFP S++ VS V + + +G IP++ L+ I + +P +S
Sbjct: 2825 L-IFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWA 2883
Query: 1168 ---RHSQPTVLN--LTSPEA-----LWVNVTSGEATLGIQLHW----------RPDIALT 1207
S N + P+A + ++ ++ A L +QL++ P+ L
Sbjct: 2884 ARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLA 2943
Query: 1208 LSLGYGYHPNKSSYDAQTHLVP--MVAPDELP-TWILSPQDLRFGEGVYYLTVVPESDLE 1264
+ L PN+ + A + P + D P T+ +SP R G Y+L +
Sbjct: 2944 VYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGS-RDPAGSYHLNLSSHFRWS 3002
Query: 1265 PAPGRDLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLTFFGSTFLV 1324
L V + + S C ++ E W G TSP Q CL HLT FG++ V
Sbjct: 3003 A-----LQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFV 3057
Query: 1325 MSNAINI---HQTAELFATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQDQAKVKVTVL 1381
+ + TA++ N +V+ T V Y+++ + D D ++ +
Sbjct: 3058 PPSHVRFVFPEPTADV------NYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAI-- 3109
Query: 1382 EDNDPFA----QYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERG 1437
PF ++ Y + V TG RG+ T++ V + LYG+D HL D D F R
Sbjct: 3110 ----PFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHL-DGDR-AFHRN 3163
Query: 1438 AVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSI-- 1495
++D F ++T LG + +R+WHDN G P+W++ V+V DL R +FL N WLS+
Sbjct: 3164 SLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVET 3223
Query: 1496 NVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQRVSC 1555
+++K A++ +F L + GF D HIW SI+ R RS FTR+QR +C
Sbjct: 3224 EANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATC 3283
Query: 1556 CFSLLLCTMLTSIMFW-GVPKDPAEQKMDLGKIE-FTWQEVMIGLESSILMFPINLLIVQ 1613
C LL+C L + W G D A + ++ + V +GL SS++++P+ L I+
Sbjct: 3284 CV-LLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILF 3342
Query: 1614 IFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLFKALKVP 1673
+F+ +R +VA GSP+ TP+ Q + D + S + +
Sbjct: 3343 LFRMSRSKVA----------GSPSPTPAGQQVLD---------------IDSCLDSSVLD 3377
Query: 1674 SPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKRED-PVTLTLGSSEMKEKS 1732
S L + ++ + + ++ ++ ++ V W + P L+ S
Sbjct: 3378 SSFLTFSGLH---AEAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVGSNLR 3434
Query: 1733 QCPKPKAARS-GPWKDSAYRQCLYLQLEHV----EQELRLVGPRGFSQP------HSHAQ 1781
Q + +A GP +D Y + E ++ V G S P H
Sbjct: 3435 QLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETD 3494
Query: 1782 ALRQLQTLKG----GLGVQ---------PG-TWAPAHASALQVSKPPQG-----LPWWCI 1822
L L + G L +Q PG W A+ L + +G LP WC
Sbjct: 3495 LLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCA 3554
Query: 1823 LVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKVLGFAAFF 1882
+ L VA + G + S+ WL+S + SF+ S +PLKVL A +F
Sbjct: 3555 SLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYF 3614
Query: 1883 ALVLKRV-DDEEDTVAPLPGHLLGPDPYALFRARRNSSRDVYQPPLTAAIEKMKTTHLKE 1941
+LV KR+ DE+DT+ P + P + R R PP A+ K K
Sbjct: 3615 SLVAKRLHPDEDDTLVESPA--VTPVSARVPRVR---------PPHGFALFLAKEEARKV 3663
Query: 1942 QKAFALIREILAYLGFLWMLLLVAYGQRD--PSAYHLNRHL-QHSFTRGFSGVLGFREFF 1998
++ ++R +L Y+ FL + LL +YG AY L + Q +R F + E +
Sbjct: 3664 KRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELW 3723
Query: 1999 KWANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRVQESSCPLAQQPQAYLNGCRAPYS 2058
W L+ ++G+ +S +G ++RQVR+QE+ P P+ + +S
Sbjct: 3724 PWMAHVLLPYVHGNQ-------SSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFS 3776
Query: 2059 LDAEDMADYGEGWNA--TTLSEWQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQSTS 2116
+DY GW + W Y + D + WG VY GGYV LG + +
Sbjct: 3777 -----TSDYDVGWESPHNGSGTWAYSAPDLLGAWS-WGSCAVYDSGGYVQELGLSLEESR 3830
Query: 2117 RILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRLY 2176
LR+L + WLD +RAVF+E T Y+ V L VTL LE A G +++ L
Sbjct: 3831 DRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALR 3890
Query: 2177 PFTDGWH-PFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAI----ILAS 2231
+ G P + + L+ LF +++ V + + +E +W +L L +L +
Sbjct: 3891 RLSAGLSLPLLTSVCLL--LFAVHFAVAEARTWHRE------GRWRVLRLGAWARWLLVA 3942
Query: 2232 WSALAVFVKRAVLAERDLQRCRNHR---EEGISFSETAAADAALGYIIAFLVLLSTVKLW 2288
+A V+ A L D Q R R SF + A +A + A L+ L VK
Sbjct: 3943 LTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAA 4002
Query: 2289 HLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYS 2326
LR + ++ L RA ++ G + ++ + +AY+
Sbjct: 4003 QQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYA 4040
Score = 37.7 bits (86), Expect = 0.14
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 30/199 (15%)
Query: 304 VSSNVTHQFTSPGEFTVFAECTTSEWHVTAQRQVTVRDKMETLSVTACSGLSQSGAGPLC 363
V NV H + +PGE+ + + + ++T Q V+VR + +++V G+
Sbjct: 1087 VEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGV--------- 1137
Query: 364 QAVFGDPL-WIQVELDGGTGVTYTVLLGDITLAESTTQKGSLPYNLILDRETQKLMGPGR 422
V G P+ + L GV YT GD + + +Q + T G
Sbjct: 1138 -LVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAA--------NHTYASRGTYH 1188
Query: 423 HRLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEEL 482
RLE+ N T S + V + E L GL S +E G ++++ ++ G
Sbjct: 1189 VRLEV----NNTVSGAAAQADVRVFEELRGLSVD-MSLAVEQGAPVVVSAAVQTGDNITW 1243
Query: 483 TFE------VAGLNATFSH 495
TF+ ++G AT H
Sbjct: 1244 TFDMGDGTVLSGPEATVEH 1262
Score = 34.7 bits (78), Expect = 1.2
Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 15/126 (11%)
Query: 424 RLEIQATGNTTTSTISRNITVHLVELLSGLQASWASDHLELGQDLLITISLAQGTPEELT 483
+L + A+ + + T++ N+TV + + GLQ S L L +T + + E+
Sbjct: 993 KLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVA 1052
Query: 484 F-EVAGLNATFSHE-QVSFGEPFGICRLAV-------------PVEGTFLVTMLVRNAFS 528
F G H+ Q + E F + +V G +L+T+L NAF
Sbjct: 1053 FLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFE 1112
Query: 529 NLSLEI 534
NL+ ++
Sbjct: 1113 NLTQQV 1118
>gi|5174633 receptor for egg jelly-like protein precursor [Homo
sapiens]
Length = 2253
Score = 233 bits (593), Expect = 2e-60
Identities = 179/664 (26%), Positives = 306/664 (46%), Gaps = 33/664 (4%)
Query: 1802 PAHASALQVSKPPQ-GLPWWCILVGWLLVAATSGVAAFFTMLYGLHYGRASSLRWLISMA 1860
P+ Q+ K P+ LPWWC+ V W LV ATS +++FF + YGL YG S+ WL +
Sbjct: 1556 PSQKDLQQLKKKPRIVLPWWCVYVAWFLVFATSSISSFFIVFYGLTYGYDKSIEWLFASF 1615
Query: 1861 VSFVESMFVTQPLKVLGFAAF------FALVLKRVDDEEDTVAPLPGHLLGPDPYALFRA 1914
SF +S+ + QP K++ + F + L + T L G + P+
Sbjct: 1616 CSFCQSVLLVQPSKIILLSGFRTNKPKYCKNLSWSTKYKYTEIRLDGMRMHPEEMQRIHD 1675
Query: 1915 R--RNSSRDVYQPPLTAAIEKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPS 1972
+ R +YQP I K +++A + IL + FL +LL++ R
Sbjct: 1676 QIVRIRGTRMYQPLTEDEIRIFKRKKRIKRRALLFLSYILTHFIFLALLLILIVLLRHTD 1735
Query: 1973 AYHLNRHLQHSFTRGFSGVLGFREFFKWANTTLVSNLYGH-PPGFITDGNSKLVGSAQIR 2031
++ N+ ++ F+ + V + ++W N+ L+ L+ P F+ + +SK++G +R
Sbjct: 1736 CFYYNQFIRDRFSMDLATVTKLEDIYRWLNSVLLPLLHNDLNPTFLPESSSKILGLPLMR 1795
Query: 2032 QVRVQESSCPLAQQPQAYLNG------CRAPYSLDAEDMADYGEGWNAT-------TLSE 2078
QVR + S + N C Y +D ED +Y WN + +
Sbjct: 1796 QVRAKSSEKMCLPAEKFVQNSIRREIHCHPKYGIDPEDTKNYSGFWNEVDKQAIDESTNG 1855
Query: 2079 WQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGTDRQSTSRILRY--LFDNTWLDALTRAVF 2136
+ Y+ Q + Y +G L Y GGY + ++Q + LR L ++ WLD T AV
Sbjct: 1856 FTYKPQGTQWLYYSYGLLHTYGSGGYALYFFPEQQRFNSTLRLKELQESNWLDEKTWAVV 1915
Query: 2137 VESTVYNANVNLFCIVTLTLETSALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLF 2196
+E T +N ++NLFC +++ E S LG T +L S L F D + + +F
Sbjct: 1916 LELTTFNPDINLFCSISVIFEVSQLGVVNTSISLHSFSLADF-DRKASAEIYLYVAILIF 1974
Query: 2197 LLYYMVVQGKRMSKETWGYFCSKWNLLELAIILASWSALAVFVKRAVLAERDLQRCRNHR 2256
L Y+V +G + +E Y S +NLL A+ + +F+++ LA ++ ++
Sbjct: 1975 FLAYVVDEGCIIMQERASYVRSVYNLLNFALKCIFTVLIVLFLRKHFLATGIIRFYLSNP 2034
Query: 2257 EEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMI 2316
E+ I F + D + I+ FL+ L+ +K R + + A++ A I
Sbjct: 2035 EDFIPFHAVSQVDHIMRIILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAF 2094
Query: 2317 VILTMLLAYSIASNLIFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIG 2376
V+ Y L+FG +Y L + +T+ S + F E + +LG +
Sbjct: 2095 VVSVYFFVYMAFGYLVFGQHEWNYSNLIHSTQTVFSYCVSAFQNTE-FSNNRILGVLFLS 2153
Query: 2377 SCIVFMTFVVLNLFISVILVAFSEEQK--YYQLSEEGEIVDLLLMKI---LSFLGIKSK- 2430
S ++ M V++NLF +VIL A+ E ++ Y + S+E E + L K+ SFL +SK
Sbjct: 2154 SFMLVMICVLINLFQAVILSAYEEMKQPVYEEPSDEVEAMTYLCRKLRTMFSFLTSQSKA 2213
Query: 2431 REEP 2434
++EP
Sbjct: 2214 KDEP 2217
Score = 218 bits (555), Expect = 6e-56
Identities = 122/364 (33%), Positives = 191/364 (52%), Gaps = 25/364 (6%)
Query: 1270 DLTVGITTFLSHCVFWDEVQETWDDSGCQVGPRTSPYQTHCLCNHLT------------- 1316
D V I+ F C+ +Q W + C +G +TS Y+ HC+C ++
Sbjct: 1092 DKLVRISIFSVQCLDMYGIQSEWREGYCILGEKTSWYEVHCICKNVVRARRQLGTIGLTG 1151
Query: 1317 FFGSTFLVMSNAINIHQTAEL----FATFEDNPVVVTTVGCLCVVYVLVVIWARRKDAQD 1372
T VM+ I I +L + NPV + TV + ++YV + WA +D D
Sbjct: 1152 IHLHTHYVMAKVIVIPNPVDLRLNIIKSLHQNPVTLFTVLFIILLYVGLAFWALYRDEMD 1211
Query: 1373 Q-AKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT 1431
Q + V VL DNDP+ YLVT++TG R G+ T + V V L G + H L+ P
Sbjct: 1212 QHLRGHVIVLPDNDPYDNLCYLVTIFTGSRWGSGTRANVFVQLRGTVSTSDVHCLSHPHF 1271
Query: 1432 PVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNS 1491
RG+++ FLL+T LG++ S+R+WH+N G PSWY+SR+ V +L W F+C
Sbjct: 1272 TTLYRGSINTFLLTTKSDLGDIHSIRVWHNNEGRSPSWYLSRIKVENLFSRHIWLFICQK 1331
Query: 1492 WLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRCARSSFTRVQ 1551
WLS+ D LD+ F V +R FF+ S+ + H+W+SIF+ +F R+Q
Sbjct: 1332 WLSV---DTTLDRTFHVTHPDERLTRKDFFFIDVSSNLRKNHMWFSIFASVVAKTFNRLQ 1388
Query: 1552 RVSCCFSLLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLI 1611
R+SCC ++LL ++L +IMF+ + + Q+ + + +MIG+ES ++ P+ LLI
Sbjct: 1389 RLSCCLAMLLSSLLCNIMFFNLNR----QEQTESRERKYMRSMMIGIESVLITIPVQLLI 1444
Query: 1612 VQIF 1615
+F
Sbjct: 1445 TFLF 1448
Score = 52.0 bits (123), Expect = 7e-06
Identities = 88/419 (21%), Positives = 165/419 (39%), Gaps = 61/419 (14%)
Query: 753 TALTRHAYGEDTYVISTVPPREVPACTIAPEEGTVL-TSFAIFC-NASTALGPLEFCFCL 810
T++ RH++ +I+ P ++ C I P +G L T F + C N PL + +
Sbjct: 548 TSVFRHSF-----IINHGP--QIGECKINPAKGIALITKFVVQCSNFRDKHVPLTYKIIV 600
Query: 811 ES---------------GSCLHCGPEPALPSVYLPLGEENNDFVLTVVISATNRAGDTQQ 855
G+ L+ GP+ +P +LP+G + + L + + G Q
Sbjct: 601 SDLHSVGEISSVKENTLGTILYLGPQSTVPPSFLPVGMLASQYGLKIYAQVYDSLGAFSQ 660
Query: 856 T------QAMAKVALGDTCVEDV-AFQAAVSEKIPTALQGEG--GPEQLLQLAKAVSSML 906
QA T + + +F S + T +Q + LL + +V + +
Sbjct: 661 VTLHATAQAPTDKNSSKTVLNQLLSFTVGPSSLLSTLIQKKDFLPAGYLLYIVASVLNNM 720
Query: 907 NQEHESQGSGQSLSIDVRQKVREHVLGS--LSAVTTGLEDVQRVQELAEVLREVTCRSKE 964
E + D R +R+H++ L V+T +E + ++ + ++T + E
Sbjct: 721 KTELPLR--------DDRVNLRKHLIDQSFLLPVSTLVE----IGQVVMTITKLTQKPSE 768
Query: 965 LTPSAQWEASLALQHASEALLTVSAKARPEDQRRQAATRDLFQAVGSVLEASLSNRPEEP 1024
T AQ A++ + A++AL K D+R ++ + + V + + SLSN +
Sbjct: 769 FTWDAQKRATMRVWQANQALQEYQQK----DKRFRS---EQIEIVSTGILMSLSNILK-- 819
Query: 1025 AEASSSQIATVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQGSSL 1084
+S V V+E + T+L K+PG + TP+ ++Y +++ W
Sbjct: 820 ---MTSPHQVVKDPFYVIESLSDTILANKVPGNKTTSMRTPNFNMYVKKVEKWGINQLFR 876
Query: 1085 RPDAADSATFMLPAASSLSSLEGGQEPVDIKIMSFPKSPFP-ARSHFDVSGTVGGLRVT 1142
+ + SS+ L P+ F FP + S V G R+T
Sbjct: 877 NEKHCRNCFYPTLNVSSVPGL-SANGPISTMFCDFTNDLFPWLNDQENTSVEVSGFRMT 934
>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
Length = 805
Score = 225 bits (574), Expect = 4e-58
Identities = 137/488 (28%), Positives = 241/488 (49%), Gaps = 22/488 (4%)
Query: 1948 IREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTR-------GFSGVLGFREFFKW 2000
+RE+L Y+ FL + L+ YG SAY+ + + F F + +F+ +
Sbjct: 101 LRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTGVSFQAISSMADFWDF 160
Query: 2001 ANTTLVSNLY----------GHPPGFITDGNSKLVGSAQIRQVRVQESSCPLAQQPQAYL 2050
A L+ +LY GH + L+G ++RQ++V+ SC + + + +
Sbjct: 161 AQGPLLDSLYWTKWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDI 220
Query: 2051 NGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPIWGKLTVYRGGGYVVPLGT 2110
C YS D E+ +G +N T W Y SQD+ G+ WG+LT Y GGGY + L
Sbjct: 221 LSCYDVYSPDKEEQLPFGP-FNGTA---WTYHSQDELGGFSHWGRLTSYSGGGYYLDLPG 276
Query: 2111 DRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFTHAAL 2170
RQ ++ LR L + WLD TR VF++ +VYNAN+NLFC++ L +E A G +
Sbjct: 277 SRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQI 336
Query: 2171 QSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELAIILA 2230
++++L + W F+V E+I+ +F+ YY+V + + Y S WN+L+L +IL
Sbjct: 337 RTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILL 396
Query: 2231 SWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVLLSTVKLWHL 2290
S A+ + R + R + + F A + A + + +K++
Sbjct: 397 SIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKY 456
Query: 2291 LRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYKTLFDAAETM 2350
+ N M +++ L R DI GF ++ + AY+ L+FG ++ ++ T T
Sbjct: 457 ISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQ 516
Query: 2351 VSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE-EQKYYQLSE 2409
+ LG F+Y + + + +LG + + F+ FV+LN+F+++I +SE +++ +
Sbjct: 517 FRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKD 576
Query: 2410 EGEIVDLL 2417
E ++ DLL
Sbjct: 577 ELQLSDLL 584
>gi|4505835 polycystin 2 [Homo sapiens]
Length = 968
Score = 219 bits (559), Expect = 2e-56
Identities = 154/552 (27%), Positives = 258/552 (46%), Gaps = 32/552 (5%)
Query: 1893 EDTVAPLPGHLLGPDP-YALFRARRNSSRDVYQPPLTAAIEKMKTTHLKEQKAF------ 1945
ED P P + G DP + R + L + + T L E+ +
Sbjct: 158 EDQGPPCPSPVGGGDPLHRHLPLEGQPPRVAWAERLVRGLRGLWGTRLMEESSTNREKYL 217
Query: 1946 -ALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFT---------RGFSGVLGFR 1995
+++RE++ YL FL +L ++ YG + Y+ R + F F +
Sbjct: 218 KSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDTPVSKTEKTNFKTLSSME 277
Query: 1996 EFFKWANTTLVSNLYGH-PPGFITDGNSK--------LVGSAQIRQVRVQESSCPLAQQP 2046
+F+K+ +L+ LY P T+ +++ L+G +IRQ+RV+ SC + Q
Sbjct: 278 DFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDL 337
Query: 2047 QAYLNGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPIWGKLTVYRGGGYVV 2106
+ + C YS+ +ED A +G N T W Y S+ G WG + Y G GY +
Sbjct: 338 RDEIKECYDVYSVSSEDRAPFGPR-NGTA---WIYTSEKDLNGSSHWGIIATYSGAGYYL 393
Query: 2107 PLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIVTLTLETSALGTFFT 2166
L R+ T+ + L N WLD TRA F++ +VYNAN+NLFC+V L +E A G
Sbjct: 394 DLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIP 453
Query: 2167 HAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKETWGYFCSKWNLLELA 2226
Q L+L + + F+ A E+I+ F+ YY+V + + YF S WN L++
Sbjct: 454 SWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVV 513
Query: 2227 IILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAALGYIIAFLVLLSTVK 2286
I++ S A+ + + R E LQ + + +F A I A V +K
Sbjct: 514 IVVLSVVAIGINIYRTSNVEVLLQFLED-QNTFPNFEHLAYWQIQFNNIAAVTVFFVWIK 572
Query: 2287 LWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLIFGWKLRSYKTLFDA 2346
L+ + N M+ ++ + R D+ GF I+ + LAY+ + L+FG ++ + T +
Sbjct: 573 LFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQEC 632
Query: 2347 AETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE-EQKYY 2405
T + LG N+ E+ + + VLG + + FM F++LN+F+++I +SE +
Sbjct: 633 IFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLA 692
Query: 2406 QLSEEGEIVDLL 2417
Q E E+ DL+
Sbjct: 693 QQKAEMELSDLI 704
>gi|19923084 polycystin-1L1 [Homo sapiens]
Length = 2849
Score = 219 bits (557), Expect = 3e-56
Identities = 385/1737 (22%), Positives = 666/1737 (38%), Gaps = 283/1737 (16%)
Query: 684 VTMGEDSPVAMFSWYLDNTPTEQAEPLLDACRLRGFWPRSLTLLQSNTSTLLLNSSFLQS 743
++ G PV M W + LL +G+ +T T T+ + S
Sbjct: 1118 LSAGRAEPVLMIDW---------PKALLGRAVFQGYSSSGIT---EQTVTI---KPYSLS 1162
Query: 744 RGEVIRIRATALTRHAY-GEDTYVISTVPPREVPACTIAPEEGTVL-TSFAIFCNASTAL 801
GE ++ + ++H G+ ++ P AC + P G T F++FC +
Sbjct: 1163 SGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQVQPHHGLEAHTVFSVFCMSGKPD 1222
Query: 802 GPLEFCFCLESGS--CLHCGPEPALPSVYLPLGEENNDFVLTVVISATNRAGDTQQTQAM 859
EF + + + S L+ G + V LP GE +++ + V T+ G Q +
Sbjct: 1223 FHYEFSYQIGNTSKHTLYHGRDTQYYFV-LPAGEHLDNYKVMVSTEITDGKGSKVQPCTV 1281
Query: 860 AKVAL----GDTCVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAKAVSSMLNQEHESQGS 915
L G+ C+ + + +++ K + LQ G ++ ++ +L++ +
Sbjct: 1282 VVTVLPRYHGNDCLGEDLYNSSL--KNLSTLQLMGSYTEIRNYITVITRILSRLSKED-- 1337
Query: 916 GQSLSIDVRQKVREHVLGSLSAVTTGLEDVQRVQELAEVLREVTCRSKELTPSAQWEASL 975
++ S + ++++ ++ S+ + D + + +LR++ S +L A L
Sbjct: 1338 -KTASCNQWSRIQDALISSVCRLA--FVDQEEMIGSVLMLRDLVSFSNKL---GFMSAVL 1391
Query: 976 ALQHASEALLTVSAKARPE--DQRRQAATRDLFQAVGSVLEASLSNRPEEPAEASSSQIA 1033
L++ + ALL + P D+ + L V V E S E + I+
Sbjct: 1392 ILKY-TRALLAQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVYRHEEGITVIS 1450
Query: 1034 TVLRLLRVMEHVQT------TLLLGKLPGGLPAMLATPSISVYTNRIQPWSWQGSSLRPD 1087
+L + HV T TLL L + ++ S+ V+ P G S P
Sbjct: 1451 DLLLGCLSLNHVSTGQMEFRTLLHYNLQSSVQSL---GSVQVHL----PGDLAGHS--PA 1501
Query: 1088 AADSATFMLPAASSLSSLEGGQEPVDI-KIMSFPKSPFPARSHFDVSGTVGGLRVTSPS- 1145
A++ Q P I +++ F K+P+P G V GL + + S
Sbjct: 1502 GAET-----------------QSPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSS 1544
Query: 1146 -----------------GQLIPVKNLSENIEILLPRHSQRHSQPTVLNLTSPEALWVNVT 1188
G+ + N +L R Q T L+ E+L + +
Sbjct: 1545 RRPINRQWLRKPVMVEFGEEDGLDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIE 1604
Query: 1189 SGEATLGIQLHWRPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAP-DELPTWILSPQDLR 1247
+ + L + + P S + LV + DE I P +
Sbjct: 1605 FSKPVTRA-------FPVMLLVRFSEKPTPSDF-----LVKQIYFWDESIVQIYIPAASQ 1652
Query: 1248 FGEGVYYLTVVPESDLEPAPGRDLTVGITTFLSH-----CVFWDEVQETWDDSGCQVGPR 1302
V YL+++ ++D + P + H C+FWD+ + W P
Sbjct: 1653 KDASVGYLSLL-DADYDRKPPNRYLAKAVNYTVHFQWIRCLFWDKRE--WKSERFSPQPG 1709
Query: 1303 TSPYQTHCLCNHLTFFGSTFLVMSNAINIHQTAELFATFEDNPVVVTTVGCLCVVYVLVV 1362
TSP + +C + L F + + + ++L + E+ + +G + ++Y +V
Sbjct: 1710 TSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQSHPENLLPSIFIMGSV-ILYGFLV 1768
Query: 1363 IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGERE 1422
+R+ D ++ K L++ Y V + TG R A +SKV + L G +G E
Sbjct: 1769 AKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGFRAPARLTSKVYIVLCGDNGLSE 1828
Query: 1423 PHHLADPDTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMD 1482
L+ P+ P+FER + F+LS LG LR +RLWHD+ G P W++S V+V +L
Sbjct: 1829 TKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWHDSRGPSPGWFISHVMVKELHTG 1888
Query: 1483 RKWYFLCNSWLSINVGDCVLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGHIWYSIFSRC 1542
+ W+F WLS D +++ + Q F LF+ K + +D H+W S++SR
Sbjct: 1889 QGWFFPAQCWLSAGRHDGRVER--ELTCLQGGLGFRKLFYCKFTEYLEDFHVWLSVYSRP 1946
Query: 1543 ARSSFTRVQRVSCCFSLL-LCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESS 1601
+ S + R++ FSLL + LT+++ G + P +D+ T +GL +
Sbjct: 1947 SSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQEQP---HLDVSP---TLGSFRVGLLCT 2000
Query: 1602 ILMFPINLLIVQIFQNTRPRVAKEQNTGKWDRGSPNLTPSPQPMEDGLLTPEAVTKDVSR 1661
+L P L+ +F R++KE GS + P P+ G T
Sbjct: 2001 LLASPGAQLLSLLF-----RLSKEA------PGSARVEPH-SPLRGGAQT---------- 2038
Query: 1662 IVSSLFKALKVPSPALGWDSVNLMDINSLLALVEDVIYPQNTSGQVFWEEAKKREDPVTL 1721
+ + N+ G++ + +++ +
Sbjct: 2039 ----------------------------------EAPHGPNSWGRIPDAQEPRKQPASAI 2064
Query: 1722 TLGSSEMKEK------SQCPKPKAARSGPWKDSAYRQCLYLQLEHVEQELRLVGPRGFSQ 1775
GS + K + CP PK G +H L+G
Sbjct: 2065 LSGSGRAQRKAASDNGTACPAPKLQVHG--------------ADH--SRTSLMGKSHCCP 2108
Query: 1776 PHSHAQALRQLQTLKGGLGVQPGTWAPAHASALQVSKPPQGLPWWCILVGWLLVAATSGV 1835
PH+ A + G G+ P W + ALQ PWW V W + S
Sbjct: 2109 PHTQAPS-------SGLEGLMP-QW----SRALQ--------PWWSSAV-WAICGTASLA 2147
Query: 1836 AAFFTMLYGLHYGRASSLRWLISMAVSFVESMFVTQPLKV----LGFA-------AFFAL 1884
+ T +G+ ++WL +++S V +F+TQPL V LGFA FF
Sbjct: 2148 CSLGTGFLAYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTE 2207
Query: 1885 VLKRVDDEED--------TVAPLPGHLLGPD---PYALFRARRNSSRDV--YQPPLTAAI 1931
L + D T P PD A R +R + PP A +
Sbjct: 2208 SLCEATRDLDSELAERSWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQL 2267
Query: 1932 EKMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFTRGFSGV 1991
+ +E + A +R+I + L +LL V YG+ Y LN+ ++ FTR
Sbjct: 2268 RGTRQRMRRESRTRAALRDISMDILMLLLLLCVIYGRFSQDEYSLNQAIRKEFTRNARNC 2327
Query: 1992 LG----FREFFKWANTTLVSNLY----------GHPPGFITDGNSKLVGSAQIRQVRVQE 2037
LG +++ W+ TTL+ LY G PG + G L+GS+ IRQ++V
Sbjct: 2328 LGGLRNIADWWDWSLTTLLDGLYPGGTPSARVPGAQPGAL-GGKCYLIGSSVIRQLKVFP 2386
Query: 2038 SSCPLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLS------EWQYQSQDQRQGYP 2091
L + P+ P+S ED + T S E Y + Q
Sbjct: 2387 RH--LCKPPR--------PFSALIED--------SIPTCSPEVGGPENPYLIDPENQNVT 2428
Query: 2092 IWGKLTVYRGGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCI 2151
+ G V+ LG R L L + W+D TRAV V T+YN LF
Sbjct: 2429 LNGPGGCGTREDCVLSLGRTRTEAHTALSRLRASMWIDRSTRAVSVHFTLYNPPTQLFTS 2488
Query: 2152 VTLTLETSALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKR-MSK 2210
V+L +E G+ + ++S ++ ++ +L++ L ++ VQ R M K
Sbjct: 2489 VSLRVEILPTGSLVPSSLVESFSIFRSDSALQYHLMLPQLVFLALSLIHLCVQLYRMMDK 2548
Query: 2211 ETWGYFCSKWNLLELAIILASWSALAVFVKRAVLA-ERDLQRCRNHREEGISFSETAAAD 2269
Y+ N LEL+++ S + AV LA + Q R + + A+ +
Sbjct: 2549 GVLSYWRKPRNWLELSVVGVSLTYYAVSGHLVTLAGDVTNQFHRGLCRAFMDLTLMASWN 2608
Query: 2270 AALGYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYS 2326
++ L+ L T+K +L + M ++ +R + I +V ML A S
Sbjct: 2609 QRARWLRGILLFLFTLKCVYLPGIQNTMASCSSMMRHSLPSIFVAGLVGALMLAALS 2665
>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
Length = 613
Score = 204 bits (520), Expect = 7e-52
Identities = 136/539 (25%), Positives = 255/539 (47%), Gaps = 30/539 (5%)
Query: 1933 KMKTTHLKEQKAFALIREILAYLGFLWMLLLVAYGQRDPSAYHLNRHLQHSFT------- 1985
K K + KE + ++E+L Y FL L ++ +G +P Y+LN+ + F
Sbjct: 14 KHKLHYRKEVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVPGE 73
Query: 1986 --RGFSGVLGFREFFKWANTTLVSNLY-----GHPPGFITDGNSK------LVGSAQIRQ 2032
F + +F+K+ L+ LY + + +S+ L+G ++RQ
Sbjct: 74 ERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQ 133
Query: 2033 VRVQESSCPLAQQPQAYLNGCRAPYSLDAEDMADYGEGWNATTLSEWQYQSQDQRQGYPI 2092
++V+ ++C + Q+ ++ C Y+ ED++++G N +EW+Y + + +
Sbjct: 134 LKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGLQIN----TEWRYSTSNTNSPWH- 188
Query: 2093 WGKLTVYRGGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRAVFVESTVYNANVNLFCIV 2152
WG L VYR GGY+ L + T L N+W+ TR +F++ ++YNANVNLFCI+
Sbjct: 189 WGFLGVYRNGGYIFTLSKSKSETKNKFIDLRLNSWITRGTRVIFIDFSLYNANVNLFCII 248
Query: 2153 TLTLETSALGTFFTHAALQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMVVQGKRMSKET 2212
L E A G T S++L + + F+ + E+ + +FL + + K++ +
Sbjct: 249 RLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFK 308
Query: 2213 WGYFCSKWNLLELAIILASWSALAVFVKRAVLAERDLQRCRNHREEGISFSETAAADAAL 2272
YF S WN LEL ++L + A++ V L + E+ F A
Sbjct: 309 SAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYY 368
Query: 2273 GYIIAFLVLLSTVKLWHLLRLNPKMNMITAALRRAWGDISGFMIVILTMLLAYSIASNLI 2332
IIA + + +K++ + N M+ +++ L R DI GF I+ + AY+ L+
Sbjct: 369 NNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLV 428
Query: 2333 FGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPVLGSFLIGSCIVFMTFVVLNLFIS 2392
FG ++ + T ++ + LG FN+ + +P+LG + I F+ FV+LN+F++
Sbjct: 429 FGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLA 488
Query: 2393 VILVAFSEEQKYYQLS-----EEGEIVDLLLMKILSFLGIKSKREEPGSSREQPGSLSQ 2446
+I +SE + Y + E G+++ +L +K +++ + G L++
Sbjct: 489 IINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAE 547
>gi|224458288 lipoxygenase homology domains 1 isoform 2 [Homo sapiens]
Length = 1114
Score = 76.3 bits (186), Expect = 4e-13
Identities = 43/127 (33%), Positives = 69/127 (54%), Gaps = 3/127 (2%)
Query: 1382 EDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPD--TPVFERGAV 1439
E +P Y V ++TG+ GA T +KV +T+YG G+ +L + T FERG
Sbjct: 341 EVEEPLDIVLYSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTA 400
Query: 1440 DAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
D F++ LG + ++L HDNS WYV +V +++ + ++ FLC WLS+ D
Sbjct: 401 DTFIIEAA-DLGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKED 459
Query: 1500 CVLDKVF 1506
L+++F
Sbjct: 460 GRLERLF 466
Score = 72.4 bits (176), Expect = 5e-12
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Query: 1365 ARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPH 1424
++RK + V+++ + Y V V T GA T + V + ++G +G+
Sbjct: 749 SQRKGKKTLVCEMCAVIDEEEMMEWTSYTVAVKTSDILGAGTDANVFIIIFGENGDSGTL 808
Query: 1425 HLADP-DTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDR 1483
L + FER D F + LG L LR+WHDN G P W++S V V D D
Sbjct: 809 ALKQSANWNKFERNNTDTFNFPDMLSLGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDE 868
Query: 1484 KWYFLCNSWLSINVGD 1499
++F C+ WLS + GD
Sbjct: 869 TFHFQCDCWLSKSEGD 884
Score = 62.8 bits (151), Expect = 4e-09
Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT--PVFERGAVDAFLLSTLFP 1449
+ VT+ TG ++ A T + V +TL+G + L T FER +++ F + TL
Sbjct: 66 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETL-D 124
Query: 1450 LGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
LG+L +RL HDN+G P W+V V V + + F C WL+ N D
Sbjct: 125 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNEDD 174
Score = 59.3 bits (142), Expect = 5e-08
Identities = 41/137 (29%), Positives = 64/137 (46%), Gaps = 4/137 (2%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Y +TV+TG G T S + +TLYG++G E L D FER D F++ L +
Sbjct: 649 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEIL-DIA 706
Query: 1452 ELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVG--DCVLDKVFPVA 1509
+R+ D G RP W++ R+L+ ++ F WLS G V + +
Sbjct: 707 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLSQRKGKKTLVCEMCAVID 766
Query: 1510 TEQDRKQFSHLFFMKTS 1526
E+ + S+ +KTS
Sbjct: 767 EEEMMEWTSYTVAVKTS 783
Score = 58.2 bits (139), Expect = 1e-07
Identities = 36/117 (30%), Positives = 56/117 (47%), Gaps = 3/117 (2%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPV--FERGAVDAFLLSTLFP 1449
Y V+V TG + AAT S+ + L G D ER D F RG+V+ F ++ L
Sbjct: 518 YYVSVTTGKHKDAATDSRAFIFLIGEDDERSKRIWLDYPRGKRGFSRGSVEEFYVAGL-D 576
Query: 1450 LGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDCVLDKVF 1506
+G ++ + L HD + W V + + K+ CN WL+ + GD + +VF
Sbjct: 577 VGIIKKIELGHDGASPESCWLVEELCLAVPTQGTKYMLNCNCWLAKDRGDGITSRVF 633
Score = 46.2 bits (108), Expect = 4e-04
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 12/123 (9%)
Query: 1386 PFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGE-REPHHLAD---PDTPVFERGAVDA 1441
PF Y +T+YT A T + + + +YG D + +L FER +
Sbjct: 193 PFVPYE--ITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASR 250
Query: 1442 FLLSTLFPLGEL-RSLRLWHDNSGDRPSWYVSRVLVYDLVMDR----KWYFLCNSWLSIN 1496
F++ L +GE+ +R+ H+N+G P W+ S V + L+ D+ F C+ WL+ +
Sbjct: 251 FIVE-LEDVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATS 309
Query: 1497 VGD 1499
D
Sbjct: 310 EDD 312
Score = 45.4 bits (106), Expect = 7e-04
Identities = 23/56 (41%), Positives = 31/56 (55%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTL 1447
Y V V TG+ GA T + V VT++G +G+ L +FERG+ D F L TL
Sbjct: 1045 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETL 1100
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 76.3 bits (186), Expect = 4e-13
Identities = 43/127 (33%), Positives = 69/127 (54%), Gaps = 3/127 (2%)
Query: 1382 EDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPD--TPVFERGAV 1439
E +P Y V ++TG+ GA T +KV +T+YG G+ +L + T FERG
Sbjct: 1452 EVEEPLDIVLYSVQIFTGNIPGAGTDAKVYITIYGDLGDTGERYLGKSENRTNKFERGTA 1511
Query: 1440 DAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
D F++ LG + ++L HDNS WYV +V +++ + ++ FLC WLS+ D
Sbjct: 1512 DTFIIEAA-DLGVIYKIKLRHDNSKWCADWYVEKVEIWNDTNEDEFLFLCGRWLSLKKED 1570
Query: 1500 CVLDKVF 1506
L+++F
Sbjct: 1571 GRLERLF 1577
Score = 74.7 bits (182), Expect = 1e-12
Identities = 44/108 (40%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Y V V TG+ GA T + V VT++G +G+ L +FERG+ D F L TL LG
Sbjct: 2094 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETL-ELG 2152
Query: 1452 ELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
ELR +RL HD+SG W V +V V + F C WL GD
Sbjct: 2153 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 2200
Score = 73.6 bits (179), Expect = 2e-12
Identities = 42/109 (38%), Positives = 59/109 (54%), Gaps = 2/109 (1%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Y V TG RGA T + V +TL+G +G L FE+G VD F + T +G
Sbjct: 45 YEVVTATGDVRGAGTDANVFITLFGENGLSPKLQLTSKSKSAFEKGNVDVFRVRT-NNVG 103
Query: 1452 ELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDR-KWYFLCNSWLSINVGD 1499
+ +R+ HDN+G SWY+ V+V D+ ++YF CN+WLS GD
Sbjct: 104 LIYKVRIEHDNTGLNASWYLDHVIVTDMKRPHLRYYFNCNNWLSKVEGD 152
Score = 72.4 bits (176), Expect = 5e-12
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Query: 1365 ARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPH 1424
++RK + V+++ + Y V V T GA T + V + ++G +G+
Sbjct: 1798 SQRKGKKTLVCEMCAVIDEEEMMEWTSYTVAVKTSDILGAGTDANVFIIIFGENGDSGTL 1857
Query: 1425 HLADP-DTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDR 1483
L + FER D F + LG L LR+WHDN G P W++S V V D D
Sbjct: 1858 ALKQSANWNKFERNNTDTFNFPDMLSLGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDE 1917
Query: 1484 KWYFLCNSWLSINVGD 1499
++F C+ WLS + GD
Sbjct: 1918 TFHFQCDCWLSKSEGD 1933
Score = 66.6 bits (161), Expect = 3e-10
Identities = 36/108 (33%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Y V VYTG GA T + V + ++G G+ L + + FE+GA D F+L LG
Sbjct: 174 YEVKVYTGDVIGAGTDADVFINIFGEYGDTGERRLEN-EKDNFEKGAEDRFILDAP-DLG 231
Query: 1452 ELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
+L + + H+N G W++S++++ D+ RK+ F N WL+++ D
Sbjct: 232 QLMKINVGHNNKGGSAGWFLSQIVIEDIGNKRKYDFPLNRWLALDEDD 279
Score = 66.6 bits (161), Expect = 3e-10
Identities = 40/117 (34%), Positives = 63/117 (53%), Gaps = 7/117 (5%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLD----GEREPHHLADPDTPVFERGAVDAFLLSTL 1447
Y V V TG+ A T + V +T+YG + GER P +D FE+G D F + +
Sbjct: 1024 YEVQVVTGNVPKAGTDANVYLTIYGEEYGDTGER-PLKKSDKSNK-FEQGQTDTFTIYAI 1081
Query: 1448 FPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDCVLDK 1504
LG L +R+ HDN+G+R W++ R+ + D+ + +YF C WL++ D L +
Sbjct: 1082 -DLGALTKIRIRHDNTGNRAGWFLDRIDITDMNNEITYYFPCQRWLAVEEDDGQLSR 1137
Score = 63.5 bits (153), Expect = 2e-09
Identities = 36/134 (26%), Positives = 63/134 (47%), Gaps = 1/134 (0%)
Query: 1371 QDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPD 1430
+D K++ +L Y+VTV+TG RGA T SK+ + +YG G + + +
Sbjct: 277 EDDGKIQRDILVGGAETTAITYIVTVFTGDVRGAGTKSKIYLVMYGARGNKNSGKIF-LE 335
Query: 1431 TPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCN 1490
VF+RG D F + L L + + H N G W+ +V++ + F C+
Sbjct: 336 GGVFDRGRTDIFHIELAVLLSPLSRVSVGHGNVGVNRGWFCEKVVILCPFTGIQQTFPCS 395
Query: 1491 SWLSINVGDCVLDK 1504
+WL D ++++
Sbjct: 396 NWLDEKKADGLIER 409
Score = 62.8 bits (151), Expect = 4e-09
Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 3/110 (2%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDT--PVFERGAVDAFLLSTLFP 1449
+ VT+ TG ++ A T + V +TL+G + L T FER +++ F + TL
Sbjct: 1177 FSVTIKTGVKKNAGTDANVFITLFGTQDDTGMTLLKSSKTNSDKFERDSIEIFTVETL-D 1235
Query: 1450 LGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
LG+L +RL HDN+G P W+V V V + + F C WL+ N D
Sbjct: 1236 LGDLWKVRLGHDNTGKAPGWFVDWVEVDAPSLGKCMTFPCGRWLAKNEDD 1285
Score = 62.0 bits (149), Expect = 7e-09
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 5/136 (3%)
Query: 1368 KDAQDQAKVKVTVLEDNDP-FAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHL 1426
KD D V+ + D+ + Y +++ TG GA+T S+V + LYG + L
Sbjct: 661 KDKDDGQLVRELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLYGDKSDTIKQVL 720
Query: 1427 ADPDTPV---FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDR 1483
D + FERG VD F L TL +G + L + HD++G SW++ V + +
Sbjct: 721 LVSDNNLKDYFERGRVDEFTLETL-NIGNINRLVIGHDSTGMHASWFLGSVQIRVPRQGK 779
Query: 1484 KWYFLCNSWLSINVGD 1499
++ F N WL N D
Sbjct: 780 QYTFPANRWLDKNQAD 795
Score = 61.2 bits (147), Expect = 1e-08
Identities = 40/118 (33%), Positives = 61/118 (51%), Gaps = 2/118 (1%)
Query: 1364 WARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREP 1423
W + A + +V++ E + HY V ++TG GA TS++V + +YG G+ E
Sbjct: 788 WLDKNQADGRLEVELYPSEVVEIQKLVHYEVEIWTGDVGGAGTSARVYMQIYGEKGKTEV 847
Query: 1424 HHLADPDTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVM 1481
L+ + VFER + D F L +GE+ LRL H G PSW+V V + LV+
Sbjct: 848 LFLSS-RSKVFERASKDTFQLEAA-DVGEVYKLRLGHTGEGFGPSWFVDTVWLRHLVV 903
Score = 59.3 bits (142), Expect = 5e-08
Identities = 41/137 (29%), Positives = 64/137 (46%), Gaps = 4/137 (2%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Y +TV+TG G T S + +TLYG++G E L D FER D F++ L +
Sbjct: 1698 YEMTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEIL-DIA 1755
Query: 1452 ELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVG--DCVLDKVFPVA 1509
+R+ D G RP W++ R+L+ ++ F WLS G V + +
Sbjct: 1756 PFTKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLSQRKGKKTLVCEMCAVID 1815
Query: 1510 TEQDRKQFSHLFFMKTS 1526
E+ + S+ +KTS
Sbjct: 1816 EEEMMEWTSYTVAVKTS 1832
Score = 58.9 bits (141), Expect = 6e-08
Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 2/111 (1%)
Query: 1389 QYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLF 1448
++ + + V+T + A T+S + + +YG G R L +P+ F+ G ++ F + L
Sbjct: 424 KFPWSLWVWTTDLKKAGTNSPIFIQIYGQKG-RTDEILLNPNNKWFKPGIIEKFRIE-LP 481
Query: 1449 PLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
LG +R+WHD W++ R+ + + + K+ F CN WL N D
Sbjct: 482 DLGRFYKIRVWHDKRSSGSGWHLERMTLMNTLNKDKYNFNCNRWLDANEDD 532
Score = 56.2 bits (134), Expect = 4e-07
Identities = 45/160 (28%), Positives = 75/160 (46%), Gaps = 11/160 (6%)
Query: 1388 AQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLAD--PDTPVFERGAVDAFLLS 1445
A+YH VTV TG GA T + V + L+G G+ L + +T +FE+G D F +
Sbjct: 553 ARYH--VTVCTGELEGAGTDANVYLCLFGDVGDTGERLLYNCRNNTDLFEKGNADEFTIE 610
Query: 1446 TLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDR--KWYFLCNSWLSINVGD-CVL 1502
++ + +R +R+ HD G WY+ RVLV + F C WL + D ++
Sbjct: 611 SV-TMRNVRRVRIRHDGKGSGSGWYLDRVLVREEGQPESDNVEFPCLRWLDKDKDDGQLV 669
Query: 1503 DKVFPVATEQDRKQFSHLFFMKT---SAGFQDGHIWYSIF 1539
++ P + K F + +KT S D ++ ++
Sbjct: 670 RELLPSDSSATLKNFRYHISLKTGDVSGASTDSRVYIKLY 709
Score = 46.2 bits (108), Expect = 4e-04
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 12/123 (9%)
Query: 1386 PFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGE-REPHHLAD---PDTPVFERGAVDA 1441
PF Y +T+YT A T + + + +YG D + +L FER +
Sbjct: 1304 PFVPYE--ITLYTSDVFAAGTDANIFIIIYGCDAVCTQQKYLCTNKREQKQFFERKSASR 1361
Query: 1442 FLLSTLFPLGEL-RSLRLWHDNSGDRPSWYVSRVLVYDLVMDR----KWYFLCNSWLSIN 1496
F++ L +GE+ +R+ H+N+G P W+ S V + L+ D+ F C+ WL+ +
Sbjct: 1362 FIVE-LEDVGEIIEKIRIGHNNTGMNPGWHCSHVDIRRLLPDKDGAETLTFPCDRWLATS 1420
Query: 1497 VGD 1499
D
Sbjct: 1421 EDD 1423
>gi|224458290 lipoxygenase homology domains 1 isoform 3 [Homo sapiens]
Length = 512
Score = 74.7 bits (182), Expect = 1e-12
Identities = 44/108 (40%), Positives = 56/108 (51%), Gaps = 1/108 (0%)
Query: 1392 YLVTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLG 1451
Y V V TG+ GA T + V VT++G +G+ L +FERG+ D F L TL LG
Sbjct: 395 YEVIVTTGYEPGAGTDANVFVTIFGANGDTGKRELKQKMRNLFERGSTDRFFLETL-ELG 453
Query: 1452 ELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVGD 1499
ELR +RL HD+SG W V +V V + F C WL GD
Sbjct: 454 ELRKVRLEHDSSGYCSGWLVEKVEVTNTSTGVATIFNCGRWLDKKRGD 501
Score = 72.4 bits (176), Expect = 5e-12
Identities = 43/136 (31%), Positives = 65/136 (47%), Gaps = 1/136 (0%)
Query: 1365 ARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGEREPH 1424
++RK + V+++ + Y V V T GA T + V + ++G +G+
Sbjct: 99 SQRKGKKTLVCEMCAVIDEEEMMEWTSYTVAVKTSDILGAGTDANVFIIIFGENGDSGTL 158
Query: 1425 HLADP-DTPVFERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVMDR 1483
L + FER D F + LG L LR+WHDN G P W++S V V D D
Sbjct: 159 ALKQSANWNKFERNNTDTFNFPDMLSLGHLCKLRVWHDNKGIFPGWHLSYVDVKDNSRDE 218
Query: 1484 KWYFLCNSWLSINVGD 1499
++F C+ WLS + GD
Sbjct: 219 TFHFQCDCWLSKSEGD 234
Score = 57.8 bits (138), Expect = 1e-07
Identities = 40/135 (29%), Positives = 63/135 (46%), Gaps = 4/135 (2%)
Query: 1394 VTVYTGHRRGAATSSKVTVTLYGLDGEREPHHLADPDTPVFERGAVDAFLLSTLFPLGEL 1453
+TV+TG G T S + +TLYG++G E L D FER D F++ L +
Sbjct: 1 MTVWTGDVVGGGTDSNIFMTLYGINGSTEEMQL-DKKKARFEREQNDTFIMEIL-DIAPF 58
Query: 1454 RSLRLWHDNSGDRPSWYVSRVLVYDLVMDRKWYFLCNSWLSINVG--DCVLDKVFPVATE 1511
+R+ D G RP W++ R+L+ ++ F WLS G V + + E
Sbjct: 59 TKMRIRIDGLGSRPEWFLERILLKNMNTGDLTMFYYGDWLSQRKGKKTLVCEMCAVIDEE 118
Query: 1512 QDRKQFSHLFFMKTS 1526
+ + S+ +KTS
Sbjct: 119 EMMEWTSYTVAVKTS 133
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 73.2 bits (178), Expect = 3e-12
Identities = 48/153 (31%), Positives = 64/153 (41%), Gaps = 19/153 (12%)
Query: 10 VLALRLRATTVKPEEGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDE 69
V+ L L+ E + C F D CY F F DA+ +CE + HLVFI
Sbjct: 589 VVPLALQNEPTPAPEDNGCPPHWKNFTDKCYYFSVEKEIFEDAKLFCEDKSSHLVFINTR 648
Query: 70 GTQWFLQKHISQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQAAAAPDTCG 129
Q +++K + WIGLT + E WLD ++ Y NW GQ PD G
Sbjct: 649 EEQQWIKKQMVGRESHWIGLT-----DSERENEWKWLDGTSPDYKNWKAGQ----PDNWG 699
Query: 130 HIGRGP---------SSEWVTSDCAQTFAFMCE 153
H G GP + +W C F+CE
Sbjct: 700 H-GHGPGEDCAGLIYAGQWNDFQCEDVNNFICE 731
>gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo
sapiens]
Length = 316
Score = 62.8 bits (151), Expect = 4e-09
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 19/145 (13%)
Query: 24 EGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDR 83
EG+ C + V +D+CY F G ++ +A+ +C+ + HLV I Q F+QK++
Sbjct: 177 EGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLG-SA 235
Query: 84 EWWIGLTWNLARNGTTEGPGTWLDTSNVT--YSNWHGGQ-------AAAAPDTCGHIGRG 134
W+GL+ EG W+D ++ + NW GQ + C H
Sbjct: 236 YTWMGLS-------DPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHF--H 286
Query: 135 PSSEWVTSDCAQTFAFMCEFRVGQS 159
P W C + + ++CE +GQ+
Sbjct: 287 PDGRWNDDVCQRPYHWVCEAGLGQT 311
>gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo
sapiens]
Length = 292
Score = 62.8 bits (151), Expect = 4e-09
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 19/145 (13%)
Query: 24 EGSFCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDR 83
EG+ C + V +D+CY F G ++ +A+ +C+ + HLV I Q F+QK++
Sbjct: 153 EGTCCPVNWVEHQDSCYWFSHSGMSWAEAEKYCQLKNAHLVVINSREEQNFVQKYLG-SA 211
Query: 84 EWWIGLTWNLARNGTTEGPGTWLDTSNVT--YSNWHGGQ-------AAAAPDTCGHIGRG 134
W+GL+ EG W+D ++ + NW GQ + C H
Sbjct: 212 YTWMGLS-------DPEGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHF--H 262
Query: 135 PSSEWVTSDCAQTFAFMCEFRVGQS 159
P W C + + ++CE +GQ+
Sbjct: 263 PDGRWNDDVCQRPYHWVCEAGLGQT 287
>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
Length = 292
Score = 57.0 bits (136), Expect = 2e-07
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 21/138 (15%)
Query: 28 CSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWI 87
C + V + +CY F G+ + +A+ +C+ + HLV I Q F+ +H + WI
Sbjct: 158 CPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQH-TNPFNTWI 216
Query: 88 GLTWNLARNGTTEGPGTWLDTSNVTYS----------NWHGGQAAAAPDTCGHIGRGPSS 137
GLT ++G W+D ++ ++ NWHG + + D C + P
Sbjct: 217 GLT-------DSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSED-CVEV--QPDG 266
Query: 138 EWVTSDCAQTFAFMCEFR 155
W C Q + ++CE R
Sbjct: 267 RWNDDFCLQVYRWVCEKR 284
>gi|18426875 asialoglycoprotein receptor 2 isoform b [Homo sapiens]
Length = 287
Score = 57.0 bits (136), Expect = 2e-07
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 21/138 (15%)
Query: 28 CSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWI 87
C + V + +CY F G+ + +A+ +C+ + HLV I Q F+ +H + WI
Sbjct: 153 CPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQH-TNPFNTWI 211
Query: 88 GLTWNLARNGTTEGPGTWLDTSNVTYS----------NWHGGQAAAAPDTCGHIGRGPSS 137
GLT ++G W+D ++ ++ NWHG + + D C + P
Sbjct: 212 GLT-------DSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSED-CVEV--QPDG 261
Query: 138 EWVTSDCAQTFAFMCEFR 155
W C Q + ++CE R
Sbjct: 262 RWNDDFCLQVYRWVCEKR 279
>gi|18426873 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 57.0 bits (136), Expect = 2e-07
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 21/138 (15%)
Query: 28 CSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWI 87
C + V + +CY F G+ + +A+ +C+ + HLV I Q F+ +H + WI
Sbjct: 177 CPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQH-TNPFNTWI 235
Query: 88 GLTWNLARNGTTEGPGTWLDTSNVTYS----------NWHGGQAAAAPDTCGHIGRGPSS 137
GLT ++G W+D ++ ++ NWHG + + D C + P
Sbjct: 236 GLT-------DSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSED-CVEV--QPDG 285
Query: 138 EWVTSDCAQTFAFMCEFR 155
W C Q + ++CE R
Sbjct: 286 RWNDDFCLQVYRWVCEKR 303
>gi|4502253 asialoglycoprotein receptor 2 isoform a [Homo sapiens]
Length = 311
Score = 57.0 bits (136), Expect = 2e-07
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 21/138 (15%)
Query: 28 CSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWI 87
C + V + +CY F G+ + +A+ +C+ + HLV I Q F+ +H + WI
Sbjct: 177 CPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQH-TNPFNTWI 235
Query: 88 GLTWNLARNGTTEGPGTWLDTSNVTYS----------NWHGGQAAAAPDTCGHIGRGPSS 137
GLT ++G W+D ++ ++ NWHG + + D C + P
Sbjct: 236 GLT-------DSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSED-CVEV--QPDG 285
Query: 138 EWVTSDCAQTFAFMCEFR 155
W C Q + ++CE R
Sbjct: 286 RWNDDFCLQVYRWVCEKR 303
>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
Length = 1029
Score = 55.5 bits (132), Expect = 7e-07
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 1358 YVLVVIWARRKDAQDQAKVKVTVLEDNDPFAQYH-YLVTVYTGHRRGAATSSKVTVTLYG 1416
YV V W R + + +L P Y V V TG A T + V ++++G
Sbjct: 8 YVPVQRWLARDQEDGEICREFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISIHG 67
Query: 1417 LDGEREPHHLADPDTPV-FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVL 1475
G+ L + F RG D F L + LG+L + + HD G W++ V+
Sbjct: 68 EKGDTGSRQLFRSKSSFNFLRGQTDTFFLEAVH-LGDLCKIVIGHDGLGPGNGWFLDDVV 126
Query: 1476 VYDLVMDRKWYFLCNSWLSINVGDC 1500
+ D + ++ F C+ WL DC
Sbjct: 127 IKDPTTNYEYAFFCHRWLDQGEDDC 151
Score = 52.4 bits (124), Expect = 6e-06
Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Query: 1363 IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGERE 1422
+W R A ++ V++ Y V VYTG + A T S+V + L+G G+
Sbjct: 607 VWLSRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDSG 666
Query: 1423 PHHLADPDTPV-FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVM 1481
L + V F+RG +D F ++ + LG+L+ + L + S WY +V+V +
Sbjct: 667 LRQLYKSNMQVKFQRGQIDKFQVAAV-SLGKLQKVLLRCEASDKSQYWYCEQVIVREPGT 725
Query: 1482 DRKWYFLCNS 1491
+ F C S
Sbjct: 726 TSESIFTCQS 735
>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
sapiens]
Length = 1029
Score = 55.5 bits (132), Expect = 7e-07
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 1358 YVLVVIWARRKDAQDQAKVKVTVLEDNDPFAQYH-YLVTVYTGHRRGAATSSKVTVTLYG 1416
YV V W R + + +L P Y V V TG A T + V ++++G
Sbjct: 8 YVPVQRWLARDQEDGEICREFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISIHG 67
Query: 1417 LDGEREPHHLADPDTPV-FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVL 1475
G+ L + F RG D F L + LG+L + + HD G W++ V+
Sbjct: 68 EKGDTGSRQLFRSKSSFNFLRGQTDTFFLEAVH-LGDLCKIVIGHDGLGPGNGWFLDDVV 126
Query: 1476 VYDLVMDRKWYFLCNSWLSINVGDC 1500
+ D + ++ F C+ WL DC
Sbjct: 127 IKDPTTNYEYAFFCHRWLDQGEDDC 151
Score = 52.4 bits (124), Expect = 6e-06
Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Query: 1363 IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGERE 1422
+W R A ++ V++ Y V VYTG + A T S+V + L+G G+
Sbjct: 607 VWLSRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDSG 666
Query: 1423 PHHLADPDTPV-FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVM 1481
L + V F+RG +D F ++ + LG+L+ + L + S WY +V+V +
Sbjct: 667 LRQLYKSNMQVKFQRGQIDKFQVAAV-SLGKLQKVLLRCEASDKSQYWYCEQVIVREPGT 725
Query: 1482 DRKWYFLCNS 1491
+ F C S
Sbjct: 726 TSESIFTCQS 735
>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
sapiens]
Length = 1029
Score = 55.5 bits (132), Expect = 7e-07
Identities = 39/145 (26%), Positives = 61/145 (42%), Gaps = 3/145 (2%)
Query: 1358 YVLVVIWARRKDAQDQAKVKVTVLEDNDPFAQYH-YLVTVYTGHRRGAATSSKVTVTLYG 1416
YV V W R + + +L P Y V V TG A T + V ++++G
Sbjct: 8 YVPVQRWLARDQEDGEICREFPLLSKGQPVLPVTIYEVNVATGELWNAGTVANVYISIHG 67
Query: 1417 LDGEREPHHLADPDTPV-FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVL 1475
G+ L + F RG D F L + LG+L + + HD G W++ V+
Sbjct: 68 EKGDTGSRQLFRSKSSFNFLRGQTDTFFLEAVH-LGDLCKIVIGHDGLGPGNGWFLDDVV 126
Query: 1476 VYDLVMDRKWYFLCNSWLSINVGDC 1500
+ D + ++ F C+ WL DC
Sbjct: 127 IKDPTTNYEYAFFCHRWLDQGEDDC 151
Score = 52.4 bits (124), Expect = 6e-06
Identities = 36/130 (27%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Query: 1363 IWARRKDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTVTLYGLDGERE 1422
+W R A ++ V++ Y V VYTG + A T S+V + L+G G+
Sbjct: 607 VWLSRIQADGDVVCELPVVKGGQAIFPLRYQVDVYTGQLKHAETESEVFLCLFGERGDSG 666
Query: 1423 PHHLADPDTPV-FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRPSWYVSRVLVYDLVM 1481
L + V F+RG +D F ++ + LG+L+ + L + S WY +V+V +
Sbjct: 667 LRQLYKSNMQVKFQRGQIDKFQVAAV-SLGKLQKVLLRCEASDKSQYWYCEQVIVREPGT 725
Query: 1482 DRKWYFLCNS 1491
+ F C S
Sbjct: 726 TSESIFTCQS 735
>gi|55953106 phospholipase A2 receptor 1 isoform 2 precursor [Homo
sapiens]
Length = 1324
Score = 54.3 bits (129), Expect = 1e-06
Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 11/120 (9%)
Query: 39 CYEFVPLGR-TFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDR-EWWIGLTWNLARN 96
CY+F L ++ +A S C+ QGG L+ I DE + F+++H+S E W+GL N
Sbjct: 242 CYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGL------N 295
Query: 97 GTTEGPG-TWLDTSNVTYSNW--HGGQAAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCE 153
E G W D + + Y NW D CG S W + DC T ++C+
Sbjct: 296 QLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICK 355
Score = 43.5 bits (101), Expect = 0.003
Identities = 35/124 (28%), Positives = 51/124 (41%), Gaps = 25/124 (20%)
Query: 47 RTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHI-SQDREWWIGLTWNLARNGTTEGPGTW 105
+ + AQ +C +GG LV I+ E Q F+ ++ Q WIGL +N E TW
Sbjct: 982 KNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGL-----QNDDYE---TW 1033
Query: 106 LDTSNVTYSNWHGGQAAAAPD-----------TCGHIGRGP----SSEWVTSDCA-QTFA 149
L+ V YSNW P C + P + +W DC + +
Sbjct: 1034 LNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYG 1093
Query: 150 FMCE 153
F+CE
Sbjct: 1094 FVCE 1097
Score = 35.8 bits (81), Expect = 0.53
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 9/80 (11%)
Query: 41 EFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHI------SQDREWWIGLTWNLA 94
E V + RT+R+A+++CE G HL + F+ + + +++R++WIG
Sbjct: 684 EKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFN---K 740
Query: 95 RNGTTEGPGTWLDTSNVTYS 114
RN G W D + V S
Sbjct: 741 RNPLNAGSWEWSDRTPVVSS 760
Score = 34.3 bits (77), Expect = 1.6
Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 13/126 (10%)
Query: 35 FRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQ----DREWWIGLT 90
++DA Y F + + + C L+ I Q F+ I WWIGL
Sbjct: 819 YQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQ 878
Query: 91 WNLARNGTTEGPGTWLDTSNVTYSNWHGGQAAAA---PDTCGHIGRGPSSEWVTSDCAQT 147
A + W D + V Y NW G+ CG I + W + +C+ +
Sbjct: 879 EERANDEFR-----WRDGTPVIYQNWDTGRERTVNNQSQRCGFIS-SITGLWGSEECSVS 932
Query: 148 FAFMCE 153
+C+
Sbjct: 933 MPSICK 938
Score = 32.3 bits (72), Expect = 5.9
Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 19 TVKPEEGSFCSNSQVA---FRDACYEFVPL--GRTFRDAQSWCEGQGGHLVFIQDEGTQW 73
T + E CS + + F+ CY F + +F A +C+ +G +L+ I+DE
Sbjct: 1238 TRQSEHPELCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENA 1297
Query: 74 FLQKHI 79
FL + +
Sbjct: 1298 FLLEEL 1303
>gi|55953104 phospholipase A2 receptor 1 isoform 1 precursor [Homo
sapiens]
Length = 1463
Score = 54.3 bits (129), Expect = 1e-06
Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 11/120 (9%)
Query: 39 CYEFVPLGR-TFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDR-EWWIGLTWNLARN 96
CY+F L ++ +A S C+ QGG L+ I DE + F+++H+S E W+GL N
Sbjct: 242 CYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGL------N 295
Query: 97 GTTEGPG-TWLDTSNVTYSNW--HGGQAAAAPDTCGHIGRGPSSEWVTSDCAQTFAFMCE 153
E G W D + + Y NW D CG S W + DC T ++C+
Sbjct: 296 QLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICK 355
Score = 43.5 bits (101), Expect = 0.003
Identities = 35/124 (28%), Positives = 51/124 (41%), Gaps = 25/124 (20%)
Query: 47 RTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHI-SQDREWWIGLTWNLARNGTTEGPGTW 105
+ + AQ +C +GG LV I+ E Q F+ ++ Q WIGL +N E TW
Sbjct: 982 KNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGL-----QNDDYE---TW 1033
Query: 106 LDTSNVTYSNWHGGQAAAAPD-----------TCGHIGRGP----SSEWVTSDCA-QTFA 149
L+ V YSNW P C + P + +W DC + +
Sbjct: 1034 LNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYG 1093
Query: 150 FMCE 153
F+CE
Sbjct: 1094 FVCE 1097
Score = 42.0 bits (97), Expect = 0.007
Identities = 38/151 (25%), Positives = 62/151 (41%), Gaps = 26/151 (17%)
Query: 19 TVKPEEGSFCSNSQVA---FRDACYEFVPL--GRTFRDAQSWCEGQGGHLVFIQDEGTQW 73
T + E CS + + F+ CY F + +F A +C+ +G +L+ I+DE
Sbjct: 1238 TRQSEHPELCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEGSNLLTIKDEAENA 1297
Query: 74 FLQKHI----SQDREWWIGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQAAAAPDT-- 127
FL + + S + W+ ++ N T + W D + SNW PDT
Sbjct: 1298 FLLEELFAFGSSVQMVWLNAQFD-GNNETIK----WFDGTPTDQSNW----GIRKPDTDY 1348
Query: 128 -----CGHIGRGPSSEWVTSDCAQTFAFMCE 153
C + R P W S C + F+C+
Sbjct: 1349 FKPHHCVAL-RIPEGLWQLSPCQEKKGFICK 1378
Score = 35.8 bits (81), Expect = 0.53
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 9/80 (11%)
Query: 41 EFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHI------SQDREWWIGLTWNLA 94
E V + RT+R+A+++CE G HL + F+ + + +++R++WIG
Sbjct: 684 EKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFN---K 740
Query: 95 RNGTTEGPGTWLDTSNVTYS 114
RN G W D + V S
Sbjct: 741 RNPLNAGSWEWSDRTPVVSS 760
Score = 34.3 bits (77), Expect = 1.6
Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 13/126 (10%)
Query: 35 FRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQ----DREWWIGLT 90
++DA Y F + + + C L+ I Q F+ I WWIGL
Sbjct: 819 YQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQ 878
Query: 91 WNLARNGTTEGPGTWLDTSNVTYSNWHGGQAAAA---PDTCGHIGRGPSSEWVTSDCAQT 147
A + W D + V Y NW G+ CG I + W + +C+ +
Sbjct: 879 EERANDEFR-----WRDGTPVIYQNWDTGRERTVNNQSQRCGFIS-SITGLWGSEECSVS 932
Query: 148 FAFMCE 153
+C+
Sbjct: 933 MPSICK 938
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 53.5 bits (127), Expect = 2e-06
Identities = 34/130 (26%), Positives = 56/130 (43%), Gaps = 10/130 (7%)
Query: 27 FCSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWW 86
FC+ AF+ ACY+ R++ +A++ C G HL I Q F+ + + W
Sbjct: 687 FCNPGWDAFQGACYKHFSTRRSWEEAETQCRMYGAHLASISTPEEQDFINNRYREYQ--W 744
Query: 87 IGLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQAAA---APDTCGHIGRGPSSEWVTSD 143
IGL + T EG W D + Y NW+ GQ + + + C + +W
Sbjct: 745 IGL-----NDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDVP 799
Query: 144 CAQTFAFMCE 153
C ++ C+
Sbjct: 800 CNYHLSYTCK 809
>gi|20149533 Fc fragment of IgE, low affinity II, receptor for
(CD23A) [Homo sapiens]
Length = 321
Score = 53.1 bits (126), Expect = 3e-06
Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
Query: 28 CSNSQVAFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQDEGTQWFLQKHISQDREWWI 87
C + F+ CY F + + A+ C+ G LV I Q FL KH S WI
Sbjct: 163 CPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGS-WI 221
Query: 88 GLTWNLARNGTTEGPGTWLDTSNVTYSNWHGGQAAAAPDTCGHIGRGPSSEWVTSDCAQT 147
GL RN +G W+D S+V YSNW G+ + + S W + C +
Sbjct: 222 GL-----RNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRK 276
Query: 148 F-AFMCE 153
A++C+
Sbjct: 277 LGAWVCD 283
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,495,937
Number of Sequences: 37866
Number of extensions: 4477836
Number of successful extensions: 11192
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 90
Number of HSP's that attempted gapping in prelim test: 10779
Number of HSP's gapped (non-prelim): 360
length of query: 2459
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2340
effective length of database: 13,741,464
effective search space: 32155025760
effective search space used: 32155025760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.