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Search of human proteins with 115648022
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
(515 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115648063 solute carrier family 7 (cationic amino acid transp... 1028 0.0
gi|115648022 solute carrier family 7 (cationic amino acid transp... 1028 0.0
gi|186910308 solute carrier family 7 member 7 [Homo sapiens] 759 0.0
gi|186910306 solute carrier family 7 member 7 [Homo sapiens] 759 0.0
gi|186910304 solute carrier family 7 member 7 [Homo sapiens] 759 0.0
gi|33286428 solute carrier family 7 (cationic amino acid transpo... 495 e-140
gi|71979932 solute carrier family 7 (cationic amino acid transpo... 484 e-137
gi|9790235 solute carrier family 7, member 10 [Homo sapiens] 454 e-128
gi|7657683 solute carrier family 7, (cationic amino acid transpo... 449 e-126
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 411 e-115
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 411 e-115
gi|33286430 solute carrier family 7 (cationic amino acid transpo... 281 1e-75
gi|71999149 solute carrier family 7, (cationic amino acid transp... 261 1e-69
gi|110347453 solute carrier family 7 (cationic amino acid transp... 105 8e-23
gi|4507047 solute carrier family 7 (cationic amino acid transpor... 90 6e-18
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 89 1e-17
gi|114326550 solute carrier family 7 (cationic amino acid transp... 86 1e-16
gi|114326544 solute carrier family 7 (cationic amino acid transp... 86 1e-16
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 84 2e-16
gi|181337167 solute carrier family 7 (cationic amino acid transp... 78 2e-14
gi|198041678 solute carrier family 12 (potassium-chloride transp... 36 0.074
gi|11968148 solute carrier family 12 (potassium-chloride transpo... 36 0.074
gi|38569457 solute carrier family 12, member 8 [Homo sapiens] 32 1.4
gi|194239643 activating transcription factor 7 isoform 3 [Homo s... 32 1.8
gi|5802980 activating transcription factor 7 isoform 2 [Homo sap... 32 1.8
gi|194239640 activating transcription factor 7 isoform 1 [Homo s... 32 1.8
gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens] 30 4.0
gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Ho... 30 4.0
gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Ho... 30 4.0
gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens] 30 5.3
>gi|115648063 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 1028 bits (2658), Expect = 0.0
Identities = 515/515 (100%), Positives = 515/515 (100%)
Query: 1 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60
MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG
Sbjct: 1 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60
Query: 61 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120
SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG
Sbjct: 61 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120
Query: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180
GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV
Sbjct: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180
Query: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240
NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL
Sbjct: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240
Query: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300
YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS
Sbjct: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300
Query: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360
SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH
Sbjct: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360
Query: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420
IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR
Sbjct: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420
Query: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480
PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI
Sbjct: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480
Query: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515
RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
Sbjct: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515
>gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
Length = 515
Score = 1028 bits (2658), Expect = 0.0
Identities = 515/515 (100%), Positives = 515/515 (100%)
Query: 1 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60
MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG
Sbjct: 1 MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60
Query: 61 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120
SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG
Sbjct: 61 SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120
Query: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180
GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV
Sbjct: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180
Query: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240
NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL
Sbjct: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240
Query: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300
YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS
Sbjct: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300
Query: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360
SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH
Sbjct: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360
Query: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420
IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR
Sbjct: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420
Query: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480
PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI
Sbjct: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480
Query: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515
RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
Sbjct: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515
>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 759 bits (1959), Expect = 0.0
Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)
Query: 20 SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75
SQ +VE D +SP E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 11 SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67
Query: 76 SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135
S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 68 SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
Query: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195
EPT QAIIAITFANY++QP FPSC PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187
Query: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255
TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247
Query: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315
VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307
Query: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375
F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN
Sbjct: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367
Query: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435
MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427
Query: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495
++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR Q LC
Sbjct: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487
Query: 496 FCVLTELDVAEEKKDERKTD 515
V E+D+ + + ++ D
Sbjct: 488 MSVAAEMDLEDGGEMPKQRD 507
>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 759 bits (1959), Expect = 0.0
Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)
Query: 20 SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75
SQ +VE D +SP E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 11 SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67
Query: 76 SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135
S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 68 SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
Query: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195
EPT QAIIAITFANY++QP FPSC PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187
Query: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255
TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247
Query: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315
VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307
Query: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375
F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN
Sbjct: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367
Query: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435
MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427
Query: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495
++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR Q LC
Sbjct: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487
Query: 496 FCVLTELDVAEEKKDERKTD 515
V E+D+ + + ++ D
Sbjct: 488 MSVAAEMDLEDGGEMPKQRD 507
>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
Length = 511
Score = 759 bits (1959), Expect = 0.0
Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)
Query: 20 SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75
SQ +VE D +SP E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 11 SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67
Query: 76 SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135
S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 68 SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127
Query: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195
EPT QAIIAITFANY++QP FPSC PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187
Query: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255
TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247
Query: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315
VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307
Query: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375
F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN
Sbjct: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367
Query: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435
MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427
Query: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495
++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR Q LC
Sbjct: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487
Query: 496 FCVLTELDVAEEKKDERKTD 515
V E+D+ + + ++ D
Sbjct: 488 MSVAAEMDLEDGGEMPKQRD 507
>gi|33286428 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform a [Homo
sapiens]
Length = 535
Score = 495 bits (1274), Expect = e-140
Identities = 238/484 (49%), Positives = 343/484 (70%), Gaps = 9/484 (1%)
Query: 25 EEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVW 84
E D S + LKKEI L++ ++VGN+IGSGIFVSPKGVL + S G++LIVW
Sbjct: 20 ESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVW 79
Query: 85 AIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA 144
+ G +VVGALCYAELG TI KSG Y+Y+ + FGG F+RLW+++LV+ PT QA+IA
Sbjct: 80 IVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIA 139
Query: 145 ITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALI 204
+TF+NY++QP FP+C PP RLLAA C+ LLT+VNC+ V+W TRVQD FT K++AL
Sbjct: 140 LTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALA 199
Query: 205 AIIVMGLVKLCQGHSEHF----QDAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEE 259
II+MG+V++C+G E+F ++AFE D+G ++LA F+Y GW+ LN+VTEE
Sbjct: 200 LIIIMGIVQICKG--EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEE 257
Query: 260 IKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWT 319
+ +P +NLP AI IS+P+VT +Y+ NVAY T ++ ++L+S+AVAVTF ++ G+ +W
Sbjct: 258 LVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWI 317
Query: 320 IPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALI 379
+PI+VALS FGG+N S+F SSRLFF G+REGHLP +L+MIH++R TPIPALLF C L+
Sbjct: 318 MPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLL 377
Query: 380 YLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFL 439
L+ D++ LINY F + F G++V GQ+ LRWK+P PRP+K+++ FPI++ + FL
Sbjct: 378 MLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFL 437
Query: 440 VIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVL 499
++ L+++ + IG+ I L+GVP YF+GVY +P + + +T +Q++C V
Sbjct: 438 LVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVY 495
Query: 500 TELD 503
E++
Sbjct: 496 PEVE 499
>gi|71979932 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 5 [Homo sapiens]
Length = 507
Score = 484 bits (1246), Expect = e-137
Identities = 230/443 (51%), Positives = 320/443 (72%), Gaps = 2/443 (0%)
Query: 30 SPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGL 89
S P E + L++ I+LLNGV+++VG +IGSGIFV+P GVL S G++L+VWA G+
Sbjct: 35 SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94
Query: 90 FSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFAN 149
FS+VGALCYAELGTTI+KSG YAY+LE +G AF++LW+ LL++ P+ Q I+A+ FA
Sbjct: 95 FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154
Query: 150 YIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVM 209
Y+++P FP+C P A +L+A C+ LLT VNC VK TRVQD F AK++AL II++
Sbjct: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214
Query: 210 GLVKLCQGHSEHFQD--AFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNL 267
G V++ +G + +FEG+ D+GN+ LALYS LF+Y GW+ LNFVTEE+ NP RNL
Sbjct: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274
Query: 268 PLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALS 327
PLAI IS+PIVTL+Y+LTN+AY+T L+ +LSS+AVAV F + G+ SW IP+ V LS
Sbjct: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334
Query: 328 CFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVF 387
CFG +N S+F SSRLFFVGSREGHLP +LSMIH + TP+P+L+F C M L+Y +D+F
Sbjct: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394
Query: 388 QLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTD 447
+IN+FSF W V L+++G ++LR ++P+ RP+K+++ P+ F + +FL+ V +
Sbjct: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454
Query: 448 TINSLIGIGIALSGVPFYFMGVY 470
+ IG I LSG+P YF GV+
Sbjct: 455 PVECGIGFTIILSGLPVYFFGVW 477
>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
Length = 523
Score = 454 bits (1168), Expect = e-128
Identities = 222/506 (43%), Positives = 336/506 (66%), Gaps = 18/506 (3%)
Query: 8 RPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSP 67
RP P+ VP T +SE + LKKEI LL+ ++++GN+IGSGIF+SP
Sbjct: 15 RPAPSPSPVPGTVPG------------ASERVALKKEIGLLSACTIIIGNIIGSGIFISP 62
Query: 68 KGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIR 127
KGVL H+ S G++L VW +GG + +G+LCYAELG I KSG YAY+ E FGG F+
Sbjct: 63 KGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLL 122
Query: 128 LWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKW 187
LW ++L++ PT A+I++TF+NY++QP FP+C PP A R+L+ AC+ LLT+VN + V+W
Sbjct: 123 LWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRW 182
Query: 188 GTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSW---DMGNLSLALYSAL 244
TR+QD FT K++AL II +GL+++ QGH E + + + W +G+L+LA
Sbjct: 183 ATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGS 242
Query: 245 FSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAV 304
F++SGW+ LN+VTEE+ + +NLP AI IS+P+VT +Y TN+AY+T ++ ++LSS+AV
Sbjct: 243 FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAV 302
Query: 305 AVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERF 364
AVTF ++ G FSW +P++VALS FGG+N +F SRL F G+REGHLP LL+MIH+
Sbjct: 303 AVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHC 362
Query: 365 TPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKL 424
TPIPALL C + ++V D + LINY SF + G++++G L LRW+ P RP+K+
Sbjct: 363 TPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKV 422
Query: 425 SVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVL 484
++ P+ + + FL++ ++ + +G+ I L+GVP +F+GV+ +P + +
Sbjct: 423 NLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFW--RSKPKCVHRLT 480
Query: 485 AAITRGTQQLCFCVLTELDVAEEKKD 510
++T Q+LCF V + D EE+++
Sbjct: 481 ESMTHWGQELCFVVYPQ-DAPEEEEN 505
>gi|7657683 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 11 [Homo sapiens]
Length = 501
Score = 449 bits (1154), Expect = e-126
Identities = 220/473 (46%), Positives = 325/473 (68%), Gaps = 5/473 (1%)
Query: 31 PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
PP E +QLK++++LL GVS+++G +IG+GIF+SPKGVL +T S GMSL +W + G+
Sbjct: 32 PP--GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVL 89
Query: 91 SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
S+ GAL YAELGTTI KSG Y YILE FG AF+R+WV LL++ P A+I++ F Y
Sbjct: 90 SLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRY 149
Query: 151 IIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMG 210
I++P F C+ P LA +L+ A I ++ +N V W R+Q T+ K+ A++ IIV G
Sbjct: 150 ILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPG 209
Query: 211 LVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLA 270
+++L +G +++F+DAF G + L LA Y +++Y+GW LNFVTEE++NPE+ +PLA
Sbjct: 210 VMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLA 269
Query: 271 IGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFG 330
I ISM IVT+ Y+LTNVAY+T +N ++L S+AVAVTF+++ G FS +PI VALSCFG
Sbjct: 270 ICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFG 329
Query: 331 GLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLI 390
+N +FA SRLF+V SREGHLP++LSMIH+ + TP+PA++ + +I L D+ L+
Sbjct: 330 SMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLL 389
Query: 391 NYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTIN 450
N+ SF+ W F+GL+V G +YLR+K P RP K+ +F P +F +F+V + L++D +
Sbjct: 390 NFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFS 449
Query: 451 SLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503
+ IG I L+GVP Y++ ++ ++P + R + ITR T Q+ V+ E D
Sbjct: 450 TGIGFVITLTGVPAYYL--FIIWDKKPRWFRIMSEKITR-TLQIILEVVPEED 499
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 411 bits (1057), Expect = e-115
Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)
Query: 18 NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77
+T + ED S + +T L+KE+ L++G+S++VG +IGSGIFVSPK VL +T +
Sbjct: 3 DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62
Query: 78 GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137
G LI+WA G+ + +GALC+AELGT ITKSG Y Y++EA+G A++ W SL+V++P
Sbjct: 63 GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122
Query: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197
T AII ++F+ Y+ P + C PP + + LAAA I ++ VN V+ G+ VQ+ FT
Sbjct: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182
Query: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257
AK+V + II+ GLV L QG++++F ++FEG+ +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242
Query: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317
EE++NP RNLPLAI I +P+VT YIL NV+Y+TV+ +++L S AVAVTF D+ S
Sbjct: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302
Query: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377
W +P+ VA S G N + F + RL +V REGH+ +LS I + R TP PA++F +A
Sbjct: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362
Query: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437
IY+I D+ L+NYFSF+ W F GL+++G + +R+ + RP+K+ V P++ + SV
Sbjct: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422
Query: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470
FLV+ P+ + T L + LSG+ FYF+ V+
Sbjct: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 411 bits (1057), Expect = e-115
Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)
Query: 18 NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77
+T + ED S + +T L+KE+ L++G+S++VG +IGSGIFVSPK VL +T +
Sbjct: 3 DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62
Query: 78 GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137
G LI+WA G+ + +GALC+AELGT ITKSG Y Y++EA+G A++ W SL+V++P
Sbjct: 63 GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122
Query: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197
T AII ++F+ Y+ P + C PP + + LAAA I ++ VN V+ G+ VQ+ FT
Sbjct: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182
Query: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257
AK+V + II+ GLV L QG++++F ++FEG+ +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242
Query: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317
EE++NP RNLPLAI I +P+VT YIL NV+Y+TV+ +++L S AVAVTF D+ S
Sbjct: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302
Query: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377
W +P+ VA S G N + F + RL +V REGH+ +LS I + R TP PA++F +A
Sbjct: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362
Query: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437
IY+I D+ L+NYFSF+ W F GL+++G + +R+ + RP+K+ V P++ + SV
Sbjct: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422
Query: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470
FLV+ P+ + T L + LSG+ FYF+ V+
Sbjct: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456
>gi|33286430 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 8 isoform b [Homo
sapiens]
Length = 332
Score = 281 bits (719), Expect = 1e-75
Identities = 136/300 (45%), Positives = 209/300 (69%), Gaps = 9/300 (3%)
Query: 209 MGLVKLCQGHSEHF----QDAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNP 263
MG+V++C+G E+F ++AFE D+G ++LA F+Y GW+ LN+VTEE+ +P
Sbjct: 1 MGIVQICKG--EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDP 58
Query: 264 ERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIA 323
+NLP AI IS+P+VT +Y+ NVAY T ++ ++L+S+AVAVTF ++ G+ +W +PI+
Sbjct: 59 YKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPIS 118
Query: 324 VALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIV 383
VALS FGG+N S+F SSRLFF G+REGHLP +L+MIH++R TPIPALLF C L+ L+
Sbjct: 119 VALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVT 178
Query: 384 EDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVP 443
D++ LINY F + F G++V GQ+ LRWK+P PRP+K+++ FPI++ + FL++
Sbjct: 179 SDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFS 238
Query: 444 LFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503
L+++ + IG+ I L+GVP YF+GVY +P + + +T +Q++C V E++
Sbjct: 239 LWSEPVVCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVYPEVE 296
>gi|71999149 solute carrier family 7, (cationic amino acid
transporter, y+ system) member 13 [Homo sapiens]
Length = 470
Score = 261 bits (666), Expect = 1e-69
Identities = 155/437 (35%), Positives = 248/437 (56%), Gaps = 13/437 (2%)
Query: 37 ETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA-SYGMSLIVWAIGGLFSVVGA 95
E +QLK+ G S ++ N+IG+GIFVSPKGVL ++ + G+SL VWA + ++
Sbjct: 5 EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTST 64
Query: 96 LCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA---ITFANYII 152
LC AE+ + SGA Y ++ FG +AF+ LW SL + G ++A + A Y I
Sbjct: 65 LCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFL----GSGVVAGQALLLAEYSI 120
Query: 153 QPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLV 212
QP FPSC P L + LA A + ++ + VK T +Q + KV L I + G+V
Sbjct: 121 QPFFPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVV 180
Query: 213 KLCQGHSEH---FQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPL 269
L +G E+ FQ+AF+ D+ +L A++ F+YSG + E+K P +P
Sbjct: 181 FLIRGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPK 240
Query: 270 AIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCF 329
I ++P+VT++Y+L N++Y TVL ++LSSDAVA+T+AD+ F +W +P A++ S F
Sbjct: 241 CIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLF 300
Query: 330 GGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQL 389
L SIF SSR ++ S+EG LP L + ++ +P A+L T+ + +I+ + L
Sbjct: 301 SNLLISIFKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDL 359
Query: 390 INYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLF-TDT 448
INY F+ + L ++G L R++EP P K+ + FP+ + V LV++PL +
Sbjct: 360 INYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPN 419
Query: 449 INSLIGIGIALSGVPFY 465
++ + + + LSG+ FY
Sbjct: 420 VHYVYVLLLVLSGLLFY 436
>gi|110347453 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 4 [Homo sapiens]
Length = 635
Score = 105 bits (263), Expect = 8e-23
Identities = 98/413 (23%), Positives = 186/413 (45%), Gaps = 32/413 (7%)
Query: 31 PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
P + S+ L++ +S L+ L VG M+GSG++V V A + L+ + + +
Sbjct: 23 PLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVA 81
Query: 91 SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
S++ ALCYAE G + ++G++Y + + G AF+ W ++L+ G A +A ++ Y
Sbjct: 82 SLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGY 140
Query: 151 I-----------IQPSFPSCDPPYLACR--LLAAACICLLTFVNCAYVKWGTRVQD---- 193
+ + S P L LAA I L + A+V G RV
Sbjct: 141 LDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLAS----AFVSCGARVSSWLNH 196
Query: 194 TFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMG--NLSLALYSALFSYSGWD 251
TF+ ++ ++ I+++G + L Q H+ A EG G + S +++ G+D
Sbjct: 197 TFSAISLLVILFIVILGFI-LAQPHN---WSADEGGFAPFGFSGVMAGTASCFYAFVGFD 252
Query: 252 TLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQ 311
+ +EE +NP R++PLAI IS+ I YIL + ++ + A+A F +
Sbjct: 253 VIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQR 312
Query: 312 TFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIP-AL 370
+ + + + L + +F+ R+ + + +G + + +H P+ L
Sbjct: 313 GYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTL 372
Query: 371 LFNCTMALIYLI--VEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRP 421
F A + L+ +E + Q ++ + + FV S++ + + P P P
Sbjct: 373 AFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425
>gi|4507047 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 1 [Homo sapiens]
Length = 629
Score = 89.7 bits (221), Expect = 6e-18
Identities = 97/422 (22%), Positives = 178/422 (42%), Gaps = 43/422 (10%)
Query: 35 SSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVG 94
S E +L + ++ + V+L VG+ +G+G++V V A + +I + I L SV+
Sbjct: 22 SREETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAI-VISFLIAALASVLA 80
Query: 95 ALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA----ITFANY 150
LCY E G + K+G++Y Y G AFI W +L++ G + +A TF
Sbjct: 81 GLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGW-NLILSYIIGTSSVARAWSATFDEL 139
Query: 151 IIQP------SFPSCDPPYLACR---LLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVV 201
I +P + + + P + + A I +LT + VK V FT V+
Sbjct: 140 IGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVL 199
Query: 202 ALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSL----------------------- 238
L I+V G VK G +++Q E G L L
Sbjct: 200 VLGFIMVSGFVK---GSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVL 256
Query: 239 -ALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISD 297
+ +++ G+D + EE+KNP++ +P+ I S+ I + Y + A ++
Sbjct: 257 SGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFC 316
Query: 298 VLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLS 357
+ ++ + F + + + + + L S+F R+ + + +G L L+
Sbjct: 317 LDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLA 376
Query: 358 MIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPK 417
++ TPI A L + +A + + D+ L++ S L L LR+ +P+
Sbjct: 377 NVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY-QPE 435
Query: 418 RP 419
+P
Sbjct: 436 QP 437
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 89.0 bits (219), Expect = 1e-17
Identities = 96/423 (22%), Positives = 173/423 (40%), Gaps = 54/423 (12%)
Query: 35 SSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVV 93
S E +L + +S ++ ++L VG+ +G+G++V V A G S++V + I L SV+
Sbjct: 24 SLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVM 81
Query: 94 GALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLL-------------------- 133
LCYAE G + K+G++Y Y G AFI W +L
Sbjct: 82 AGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEL 141
Query: 134 VVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQD 193
+ + GQ + NY +P A I LL + VK V
Sbjct: 142 LSKQIGQFLRTYFRMNYTGLAEYPD---------FFAVCLILLLAGLLSFGVKESAWVNK 192
Query: 194 TFTYAKVVALIAIIVMGLVKLCQGH---SEHFQDAFEGSSWDMGNLS-LALYSA------ 243
FT ++ L+ ++V G VK + SE F S+ + + + ++Y A
Sbjct: 193 VFTAVNILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPY 252
Query: 244 ------------LFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYT 291
+++ G+D + EE++NP++ +P+ I S+ + + Y + A
Sbjct: 253 GFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTL 312
Query: 292 VLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGH 351
++ + + V F +G + + + L SIF R+ + + +G
Sbjct: 313 MMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGL 372
Query: 352 LPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYL 411
L L+ I+ + TPI A L + +A + + D+ L++ S L L L
Sbjct: 373 LFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLIL 432
Query: 412 RWK 414
R++
Sbjct: 433 RYQ 435
>gi|114326550 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 85.5 bits (210), Expect = 1e-16
Identities = 92/408 (22%), Positives = 173/408 (42%), Gaps = 36/408 (8%)
Query: 40 QLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVVGALCY 98
+L + +S L+ V+L VG+ +G+G++V V A G S+++ + + L SV+ LCY
Sbjct: 27 RLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVLAGLCY 84
Query: 99 AELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA----ITFANYI--- 151
AE G + +SG++Y Y G AF W +L++ G A +A F N I
Sbjct: 85 AEFGARVPRSGSAYLYSYVTVGELWAFTTGW-NLILSYVIGTASVARAWSSAFDNLIGNH 143
Query: 152 ----IQPSFPSCDPPYLA--CRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIA 205
+Q S P LA A + LLT + V FT ++ L
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203
Query: 206 IIVMGLVKLCQGHSEHFQDAFE------GSSWDMGNLSLALY-------------SALFS 246
+++ G VK + + ++ +E ++ +G L + + ++
Sbjct: 204 VMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYA 263
Query: 247 YSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAV 306
+ G+D + EE +NP+R++P+ I IS+ + L Y + A ++ + +
Sbjct: 264 FVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPE 323
Query: 307 TFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTP 366
F + + + + + L S+F R+ + + +G L +L+ IH TP
Sbjct: 324 AFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTP 383
Query: 367 IPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
I A + + +A + + L++ S L + L LR++
Sbjct: 384 IIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431
>gi|114326544 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 3 [Homo sapiens]
Length = 619
Score = 85.5 bits (210), Expect = 1e-16
Identities = 92/408 (22%), Positives = 173/408 (42%), Gaps = 36/408 (8%)
Query: 40 QLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVVGALCY 98
+L + +S L+ V+L VG+ +G+G++V V A G S+++ + + L SV+ LCY
Sbjct: 27 RLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVLAGLCY 84
Query: 99 AELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA----ITFANYI--- 151
AE G + +SG++Y Y G AF W +L++ G A +A F N I
Sbjct: 85 AEFGARVPRSGSAYLYSYVTVGELWAFTTGW-NLILSYVIGTASVARAWSSAFDNLIGNH 143
Query: 152 ----IQPSFPSCDPPYLA--CRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIA 205
+Q S P LA A + LLT + V FT ++ L
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203
Query: 206 IIVMGLVKLCQGHSEHFQDAFE------GSSWDMGNLSLALY-------------SALFS 246
+++ G VK + + ++ +E ++ +G L + + ++
Sbjct: 204 VMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYA 263
Query: 247 YSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAV 306
+ G+D + EE +NP+R++P+ I IS+ + L Y + A ++ + +
Sbjct: 264 FVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPE 323
Query: 307 TFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTP 366
F + + + + + L S+F R+ + + +G L +L+ IH TP
Sbjct: 324 AFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTP 383
Query: 367 IPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
I A + + +A + + L++ S L + L LR++
Sbjct: 384 IIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 84.3 bits (207), Expect = 2e-16
Identities = 94/423 (22%), Positives = 173/423 (40%), Gaps = 55/423 (13%)
Query: 35 SSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVV 93
S E +L + +S ++ ++L VG+ +G+G++V V A G S++V + I L SV+
Sbjct: 64 SLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVM 121
Query: 94 GALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLL-------------------- 133
LCYAE G + K+G++Y Y G AFI W +L
Sbjct: 122 AGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEL 181
Query: 134 VVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQD 193
+ + GQ + NY +P A I LL + VK V
Sbjct: 182 LSKQIGQFLRTYFRMNYTGLAEYPD---------FFAVCLILLLAGLLSFGVKESAWVNK 232
Query: 194 TFTYAKVVALIAIIVMGLVKLCQGH---SEHFQDAFEGSSWDMGNLS-LALYSA------ 243
FT ++ L+ ++V G VK + SE F S+ + + + ++Y A
Sbjct: 233 VFTAVNILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPY 292
Query: 244 ------------LFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYT 291
+++ G+D + EE++NP++ +P+ I S+ + + Y + A
Sbjct: 293 GFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTL 352
Query: 292 VLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGH 351
++ + + V F +G + + + L S+F R+ F +R+G
Sbjct: 353 MMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGL 412
Query: 352 LPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYL 411
L L+ + +R +P+ A L ++ + + D+ L++ S L L L
Sbjct: 413 LFRFLARVS-KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLIL 471
Query: 412 RWK 414
R++
Sbjct: 472 RYQ 474
>gi|181337167 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 14 [Homo sapiens]
Length = 771
Score = 77.8 bits (190), Expect = 2e-14
Identities = 86/415 (20%), Positives = 167/415 (40%), Gaps = 38/415 (9%)
Query: 24 VEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV 83
VE + ++ +L + ++ ++ +SL VG+ +G+G++V V A G+ ++
Sbjct: 32 VESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVS 90
Query: 84 WAIGGLFSVVGALCYAELGTTITKS-GASYAYILEAFGGFIAFIRLW---VSLLVVEPTG 139
+ I + S++ +CYAE G + K+ G++Y Y G F+AF W + L+ G
Sbjct: 91 FIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAG 150
Query: 140 QAIIAITF---ANYII-----------------QPSFPSCDPPYLACRLLAAACICLLTF 179
+ ++ F AN+ I + S+P LLA ++T
Sbjct: 151 ASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPD---------LLALLIAVIVTI 201
Query: 180 VNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLA 239
+ VK + + + I++ GL + + Q G S + +
Sbjct: 202 IVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATC 261
Query: 240 LYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVL 299
Y+ + G+D + EE KNP ++P AI S+ I Y+ +V ++ +
Sbjct: 262 FYA----FIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTID 317
Query: 300 SSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMI 359
+ + F F + + I L S+F R+ + + +G L L+ +
Sbjct: 318 TESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHV 377
Query: 360 HIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
TP+ A + + +A + ++ + LI S L V L LR++
Sbjct: 378 SSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432
>gi|198041678 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 1 [Homo sapiens]
Length = 1139
Score = 36.2 bits (82), Expect = 0.074
Identities = 41/193 (21%), Positives = 83/193 (43%), Gaps = 15/193 (7%)
Query: 259 EIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSW 318
++++ ++++P +++ + +YI + V + + VL + G +W
Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIE-GVVLRDKFGEAVNGNLVVGTLAW 504
Query: 319 TIPIAVAL-----SCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIE-RFTPIPALLF 372
P + + +C GL S+ + RL SR+G +P L H + P ALL
Sbjct: 505 PSPWVIVIGSFFSTCGAGLQ-SLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLL 563
Query: 373 N---CTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLR---WKEPKRPRPLKLSV 426
C + ++ +++V +++ F + FV L+ Q LR W+ R LS
Sbjct: 564 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS- 622
Query: 427 FFPIVFCICSVFL 439
F + C+ +F+
Sbjct: 623 FLGMSLCLALMFI 635
>gi|11968148 solute carrier family 12 (potassium-chloride
transporter), member 5 isoform 2 [Homo sapiens]
Length = 1116
Score = 36.2 bits (82), Expect = 0.074
Identities = 41/193 (21%), Positives = 83/193 (43%), Gaps = 15/193 (7%)
Query: 259 EIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSW 318
++++ ++++P +++ + +YI + V + + VL + G +W
Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIE-GVVLRDKFGEAVNGNLVVGTLAW 481
Query: 319 TIPIAVAL-----SCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIE-RFTPIPALLF 372
P + + +C GL S+ + RL SR+G +P L H + P ALL
Sbjct: 482 PSPWVIVIGSFFSTCGAGLQ-SLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLL 540
Query: 373 N---CTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLR---WKEPKRPRPLKLSV 426
C + ++ +++V +++ F + FV L+ Q LR W+ R LS
Sbjct: 541 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS- 599
Query: 427 FFPIVFCICSVFL 439
F + C+ +F+
Sbjct: 600 FLGMSLCLALMFI 612
>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
Length = 714
Score = 32.0 bits (71), Expect = 1.4
Identities = 46/235 (19%), Positives = 92/235 (39%), Gaps = 23/235 (9%)
Query: 165 ACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQ-----GHS 219
A R ++ A + L +N A VKW R+Q + V+ + +V L G+S
Sbjct: 156 AVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYS 215
Query: 220 EHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF-VTEEIKNPERNLPL----AIGIS 274
+ G ++ F + F + +++ P ++PL A+GIS
Sbjct: 216 PELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGIS 275
Query: 275 MPI-VTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLN 333
+ + +++L + L +++ + F +F + I+ SC GGL
Sbjct: 276 WFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGF------LFLLGLYISSLASCMGGL- 328
Query: 334 ASIFASSRLFFVGSREGHLPDL--LSMIHIERFTPIPALLFNCTMALIYLIVEDV 386
+ + R+ ++E +P L L TP+ A+ + + ++ V V
Sbjct: 329 ---YGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQV 380
>gi|194239643 activating transcription factor 7 isoform 3 [Homo
sapiens]
Length = 462
Score = 31.6 bits (70), Expect = 1.8
Identities = 16/66 (24%), Positives = 31/66 (46%)
Query: 4 REPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGI 63
R+ G PT + LV + + Q + PP + + L + +S++ + + G + S
Sbjct: 163 RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSG 222
Query: 64 FVSPKG 69
+SP G
Sbjct: 223 SISPSG 228
>gi|5802980 activating transcription factor 7 isoform 2 [Homo
sapiens]
Length = 483
Score = 31.6 bits (70), Expect = 1.8
Identities = 16/66 (24%), Positives = 31/66 (46%)
Query: 4 REPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGI 63
R+ G PT + LV + + Q + PP + + L + +S++ + + G + S
Sbjct: 184 RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSG 243
Query: 64 FVSPKG 69
+SP G
Sbjct: 244 SISPSG 249
>gi|194239640 activating transcription factor 7 isoform 1 [Homo
sapiens]
Length = 494
Score = 31.6 bits (70), Expect = 1.8
Identities = 16/66 (24%), Positives = 31/66 (46%)
Query: 4 REPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGI 63
R+ G PT + LV + + Q + PP + + L + +S++ + + G + S
Sbjct: 195 RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSG 254
Query: 64 FVSPKG 69
+SP G
Sbjct: 255 SISPSG 260
>gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]
Length = 570
Score = 30.4 bits (67), Expect = 4.0
Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 27/133 (20%)
Query: 168 LLAAACICLLTFVNCAYVKWGTRVQD----TFTYAKVVALIAIIVMGL--------VKLC 215
+L C LL+F+ + TRV+ T+ K+VA + + + V+ C
Sbjct: 67 ILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWC 126
Query: 216 QGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAI---- 271
+ D + + ++G+ Y LNF + IKNPE L LA+
Sbjct: 127 VNARVNNSDPYSVALSELGDRQNESY-----------LNFARKRIKNPEGGLYLAVTLLA 175
Query: 272 GISMPIVTLIYIL 284
GI+ ++TL IL
Sbjct: 176 GITGVVITLCLIL 188
>gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Homo
sapiens]
Length = 492
Score = 30.4 bits (67), Expect = 4.0
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 371 LFNCTMALIYLIVEDVFQLINY---FSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVF 427
L C + L+ ++ I Y F+ W G +V +L P+ K V+
Sbjct: 157 LQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVY 216
Query: 428 FPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVY 470
P F + SVF + + F I L+G PFYF ++
Sbjct: 217 LPTAFLLSSVFWIFMTWF-------ILFFPDLAGAPFYFSFIF 252
>gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Homo
sapiens]
Length = 622
Score = 30.4 bits (67), Expect = 4.0
Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 371 LFNCTMALIYLIVEDVFQLINY---FSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVF 427
L C + L+ ++ I Y F+ W G +V +L P+ K V+
Sbjct: 287 LQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVY 346
Query: 428 FPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVY 470
P F + SVF + + F I L+G PFYF ++
Sbjct: 347 LPTAFLLSSVFWIFMTWF-------ILFFPDLAGAPFYFSFIF 382
>gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]
Length = 245
Score = 30.0 bits (66), Expect = 5.3
Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 7/108 (6%)
Query: 41 LKKEISLLNGVSLVVG-NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYA 99
LKK +SLLNG V G ++G GI G + S + +G L V+G +
Sbjct: 11 LKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLGLSSAYLLHVGNLCLVMGCI--- 67
Query: 100 ELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITF 147
T + Y E+ G + I V +L++E T ++ + F
Sbjct: 68 ---TVLLGCAGWYGATKESRGTLLFCILSMVIVLIMEVTAATVVLLFF 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.141 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,686,983
Number of Sequences: 37866
Number of extensions: 803739
Number of successful extensions: 2701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2631
Number of HSP's gapped (non-prelim): 41
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.