Guide to the Human Genome
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Search of human proteins with 115648022

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115648022 solute carrier family 7 (cationic amino acid
transporter, y+ system), member 6 [Homo sapiens]
         (515 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115648063 solute carrier family 7 (cationic amino acid transp...  1028   0.0  
gi|115648022 solute carrier family 7 (cationic amino acid transp...  1028   0.0  
gi|186910308 solute carrier family 7 member 7 [Homo sapiens]          759   0.0  
gi|186910306 solute carrier family 7 member 7 [Homo sapiens]          759   0.0  
gi|186910304 solute carrier family 7 member 7 [Homo sapiens]          759   0.0  
gi|33286428 solute carrier family 7 (cationic amino acid transpo...   495   e-140
gi|71979932 solute carrier family 7 (cationic amino acid transpo...   484   e-137
gi|9790235 solute carrier family 7, member 10 [Homo sapiens]          454   e-128
gi|7657683 solute carrier family 7, (cationic amino acid transpo...   449   e-126
gi|187423910 solute carrier family 7, member 9 [Homo sapiens]         411   e-115
gi|7657591 solute carrier family 7, member 9 [Homo sapiens]           411   e-115
gi|33286430 solute carrier family 7 (cationic amino acid transpo...   281   1e-75
gi|71999149 solute carrier family 7, (cationic amino acid transp...   261   1e-69
gi|110347453 solute carrier family 7 (cationic amino acid transp...   105   8e-23
gi|4507047 solute carrier family 7 (cationic amino acid transpor...    90   6e-18
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s...    89   1e-17
gi|114326550 solute carrier family 7 (cationic amino acid transp...    86   1e-16
gi|114326544 solute carrier family 7 (cationic amino acid transp...    86   1e-16
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s...    84   2e-16
gi|181337167 solute carrier family 7 (cationic amino acid transp...    78   2e-14
gi|198041678 solute carrier family 12 (potassium-chloride transp...    36   0.074
gi|11968148 solute carrier family 12 (potassium-chloride transpo...    36   0.074
gi|38569457 solute carrier family 12, member 8 [Homo sapiens]          32   1.4  
gi|194239643 activating transcription factor 7 isoform 3 [Homo s...    32   1.8  
gi|5802980 activating transcription factor 7 isoform 2 [Homo sap...    32   1.8  
gi|194239640 activating transcription factor 7 isoform 1 [Homo s...    32   1.8  
gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]            30   4.0  
gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Ho...    30   4.0  
gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Ho...    30   4.0  
gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]        30   5.3  

>gi|115648063 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score = 1028 bits (2658), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 1   MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60
           MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG
Sbjct: 1   MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60

Query: 61  SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120
           SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG
Sbjct: 61  SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120

Query: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180
           GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV
Sbjct: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180

Query: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240
           NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL
Sbjct: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240

Query: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300
           YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS
Sbjct: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300

Query: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360
           SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH
Sbjct: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360

Query: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420
           IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR
Sbjct: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420

Query: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480
           PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI
Sbjct: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480

Query: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515
           RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
Sbjct: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515


>gi|115648022 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 6 [Homo sapiens]
          Length = 515

 Score = 1028 bits (2658), Expect = 0.0
 Identities = 515/515 (100%), Positives = 515/515 (100%)

Query: 1   MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60
           MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG
Sbjct: 1   MEAREPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIG 60

Query: 61  SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120
           SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG
Sbjct: 61  SGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFG 120

Query: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180
           GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV
Sbjct: 121 GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFV 180

Query: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240
           NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL
Sbjct: 181 NCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLAL 240

Query: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300
           YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS
Sbjct: 241 YSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLS 300

Query: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360
           SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH
Sbjct: 301 SDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIH 360

Query: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420
           IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR
Sbjct: 361 IERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPR 420

Query: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480
           PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI
Sbjct: 421 PLKLSVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFI 480

Query: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515
           RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD
Sbjct: 481 RNVLAAITRGTQQLCFCVLTELDVAEEKKDERKTD 515


>gi|186910308 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  759 bits (1959), Expect = 0.0
 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)

Query: 20  SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75
           SQ +VE     D +SP     E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 11  SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67

Query: 76  SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135
           S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 68  SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127

Query: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195
           EPT QAIIAITFANY++QP FPSC  PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187

Query: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255
           TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247

Query: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315
           VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307

Query: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375
           F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN  
Sbjct: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367

Query: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435
           MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427

Query: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495
           ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR  Q LC
Sbjct: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487

Query: 496 FCVLTELDVAEEKKDERKTD 515
             V  E+D+ +  +  ++ D
Sbjct: 488 MSVAAEMDLEDGGEMPKQRD 507


>gi|186910306 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  759 bits (1959), Expect = 0.0
 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)

Query: 20  SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75
           SQ +VE     D +SP     E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 11  SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67

Query: 76  SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135
           S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 68  SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127

Query: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195
           EPT QAIIAITFANY++QP FPSC  PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187

Query: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255
           TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247

Query: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315
           VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307

Query: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375
           F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN  
Sbjct: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367

Query: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435
           MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427

Query: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495
           ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR  Q LC
Sbjct: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487

Query: 496 FCVLTELDVAEEKKDERKTD 515
             V  E+D+ +  +  ++ D
Sbjct: 488 MSVAAEMDLEDGGEMPKQRD 507


>gi|186910304 solute carrier family 7 member 7 [Homo sapiens]
          Length = 511

 Score =  759 bits (1959), Expect = 0.0
 Identities = 368/500 (73%), Positives = 439/500 (87%), Gaps = 7/500 (1%)

Query: 20  SQSQVEE----DVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA 75
           SQ +VE     D +SP     E ++LKKEISLLNGV L+VGNMIGSGIFVSPKGVL+++A
Sbjct: 11  SQPEVETSPLGDGASP---GPEQVKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLIYSA 67

Query: 76  SYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVV 135
           S+G+SL++WA+GGLFSV GALCYAELGTTI KSGASYAYILEAFGGF+AFIRLW SLL++
Sbjct: 68  SFGLSLVIWAVGGLFSVFGALCYAELGTTIKKSGASYAYILEAFGGFLAFIRLWTSLLII 127

Query: 136 EPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTF 195
           EPT QAIIAITFANY++QP FPSC  PY A RLLAAACICLLTF+NCAYVKWGT VQD F
Sbjct: 128 EPTSQAIIAITFANYMVQPLFPSCFAPYAASRLLAAACICLLTFINCAYVKWGTLVQDIF 187

Query: 196 TYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF 255
           TYAKV+ALIA+IV G+V+L QG S HF+++FEGSS+ +G+++LALYSALFSYSGWDTLN+
Sbjct: 188 TYAKVLALIAVIVAGIVRLGQGASTHFENSFEGSSFAVGDIALALYSALFSYSGWDTLNY 247

Query: 256 VTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGM 315
           VTEEIKNPERNLPL+IGISMPIVT+IYILTNVAYYTVL++ D+L+SDAVAVTFADQ FG+
Sbjct: 248 VTEEIKNPERNLPLSIGISMPIVTIIYILTNVAYYTVLDMRDILASDAVAVTFADQIFGI 307

Query: 316 FSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCT 375
           F+W IP++VALSCFGGLNASI A+SRLFFVGSREGHLPD + MIH+ERFTP+P+LLFN  
Sbjct: 308 FNWIIPLSVALSCFGGLNASIVAASRLFFVGSREGHLPDAICMIHVERFTPVPSLLFNGI 367

Query: 376 MALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCIC 435
           MALIYL VED+FQLINY+SFSYWFFVGLS+VGQLYLRWKEP RPRPLKLSVFFPIVFC+C
Sbjct: 368 MALIYLCVEDIFQLINYYSFSYWFFVGLSIVGQLYLRWKEPDRPRPLKLSVFFPIVFCLC 427

Query: 436 SVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLC 495
           ++FLV VPL++DTINSLIGI IALSG+PFYF+ + +PE +RPL++R ++ + TR  Q LC
Sbjct: 428 TIFLVAVPLYSDTINSLIGIAIALSGLPFYFLIIRVPEHKRPLYLRRIVGSATRYLQVLC 487

Query: 496 FCVLTELDVAEEKKDERKTD 515
             V  E+D+ +  +  ++ D
Sbjct: 488 MSVAAEMDLEDGGEMPKQRD 507


>gi|33286428 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform a [Homo
           sapiens]
          Length = 535

 Score =  495 bits (1274), Expect = e-140
 Identities = 238/484 (49%), Positives = 343/484 (70%), Gaps = 9/484 (1%)

Query: 25  EEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVW 84
           E D S         + LKKEI L++   ++VGN+IGSGIFVSPKGVL +  S G++LIVW
Sbjct: 20  ESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVW 79

Query: 85  AIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA 144
            + G  +VVGALCYAELG TI KSG  Y+Y+ + FGG   F+RLW+++LV+ PT QA+IA
Sbjct: 80  IVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIA 139

Query: 145 ITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALI 204
           +TF+NY++QP FP+C PP    RLLAA C+ LLT+VNC+ V+W TRVQD FT  K++AL 
Sbjct: 140 LTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALA 199

Query: 205 AIIVMGLVKLCQGHSEHF----QDAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEE 259
            II+MG+V++C+G  E+F    ++AFE     D+G ++LA     F+Y GW+ LN+VTEE
Sbjct: 200 LIIIMGIVQICKG--EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEE 257

Query: 260 IKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWT 319
           + +P +NLP AI IS+P+VT +Y+  NVAY T ++  ++L+S+AVAVTF ++  G+ +W 
Sbjct: 258 LVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWI 317

Query: 320 IPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALI 379
           +PI+VALS FGG+N S+F SSRLFF G+REGHLP +L+MIH++R TPIPALLF C   L+
Sbjct: 318 MPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLL 377

Query: 380 YLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFL 439
            L+  D++ LINY  F  + F G++V GQ+ LRWK+P  PRP+K+++ FPI++ +   FL
Sbjct: 378 MLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFL 437

Query: 440 VIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVL 499
           ++  L+++ +   IG+ I L+GVP YF+GVY     +P    + +  +T  +Q++C  V 
Sbjct: 438 LVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVY 495

Query: 500 TELD 503
            E++
Sbjct: 496 PEVE 499


>gi|71979932 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 5 [Homo sapiens]
          Length = 507

 Score =  484 bits (1246), Expect = e-137
 Identities = 230/443 (51%), Positives = 320/443 (72%), Gaps = 2/443 (0%)

Query: 30  SPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGL 89
           S P    E + L++ I+LLNGV+++VG +IGSGIFV+P GVL    S G++L+VWA  G+
Sbjct: 35  SAPAGEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLALVVWAACGV 94

Query: 90  FSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFAN 149
           FS+VGALCYAELGTTI+KSG  YAY+LE +G   AF++LW+ LL++ P+ Q I+A+ FA 
Sbjct: 95  FSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFAT 154

Query: 150 YIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVM 209
           Y+++P FP+C  P  A +L+A  C+ LLT VNC  VK  TRVQD F  AK++AL  II++
Sbjct: 155 YLLKPLFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILL 214

Query: 210 GLVKLCQGHSEHFQD--AFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNL 267
           G V++ +G   +     +FEG+  D+GN+ LALYS LF+Y GW+ LNFVTEE+ NP RNL
Sbjct: 215 GFVQIGKGDVSNLDPNFSFEGTKLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNL 274

Query: 268 PLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALS 327
           PLAI IS+PIVTL+Y+LTN+AY+T L+   +LSS+AVAV F +   G+ SW IP+ V LS
Sbjct: 275 PLAIIISLPIVTLVYVLTNLAYFTTLSTEQMLSSEAVAVDFGNYHLGVMSWIIPVFVGLS 334

Query: 328 CFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVF 387
           CFG +N S+F SSRLFFVGSREGHLP +LSMIH +  TP+P+L+F C M L+Y   +D+F
Sbjct: 335 CFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLLYAFSKDIF 394

Query: 388 QLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTD 447
            +IN+FSF  W  V L+++G ++LR ++P+  RP+K+++  P+ F +  +FL+ V  +  
Sbjct: 395 SVINFFSFFNWLCVALAIIGMIWLRHRKPELERPIKVNLALPVFFILACLFLIAVSFWKT 454

Query: 448 TINSLIGIGIALSGVPFYFMGVY 470
            +   IG  I LSG+P YF GV+
Sbjct: 455 PVECGIGFTIILSGLPVYFFGVW 477


>gi|9790235 solute carrier family 7, member 10 [Homo sapiens]
          Length = 523

 Score =  454 bits (1168), Expect = e-128
 Identities = 222/506 (43%), Positives = 336/506 (66%), Gaps = 18/506 (3%)

Query: 8   RPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSP 67
           RP P+   VP T               +SE + LKKEI LL+  ++++GN+IGSGIF+SP
Sbjct: 15  RPAPSPSPVPGTVPG------------ASERVALKKEIGLLSACTIIIGNIIGSGIFISP 62

Query: 68  KGVLVHTASYGMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIR 127
           KGVL H+ S G++L VW +GG  + +G+LCYAELG  I KSG  YAY+ E FGG   F+ 
Sbjct: 63  KGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLL 122

Query: 128 LWVSLLVVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKW 187
           LW ++L++ PT  A+I++TF+NY++QP FP+C PP  A R+L+ AC+ LLT+VN + V+W
Sbjct: 123 LWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRW 182

Query: 188 GTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSW---DMGNLSLALYSAL 244
            TR+QD FT  K++AL  II +GL+++ QGH E  + +   + W    +G+L+LA     
Sbjct: 183 ATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGS 242

Query: 245 FSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAV 304
           F++SGW+ LN+VTEE+ +  +NLP AI IS+P+VT +Y  TN+AY+T ++  ++LSS+AV
Sbjct: 243 FAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAV 302

Query: 305 AVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERF 364
           AVTF ++  G FSW +P++VALS FGG+N  +F  SRL F G+REGHLP LL+MIH+   
Sbjct: 303 AVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHC 362

Query: 365 TPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKL 424
           TPIPALL  C    + ++V D + LINY SF  +   G++++G L LRW+ P   RP+K+
Sbjct: 363 TPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKV 422

Query: 425 SVFFPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVL 484
           ++  P+ + +   FL++    ++ +   +G+ I L+GVP +F+GV+     +P  +  + 
Sbjct: 423 NLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFW--RSKPKCVHRLT 480

Query: 485 AAITRGTQQLCFCVLTELDVAEEKKD 510
            ++T   Q+LCF V  + D  EE+++
Sbjct: 481 ESMTHWGQELCFVVYPQ-DAPEEEEN 505


>gi|7657683 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 11 [Homo sapiens]
          Length = 501

 Score =  449 bits (1154), Expect = e-126
 Identities = 220/473 (46%), Positives = 325/473 (68%), Gaps = 5/473 (1%)

Query: 31  PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
           PP    E +QLK++++LL GVS+++G +IG+GIF+SPKGVL +T S GMSL +W + G+ 
Sbjct: 32  PP--GQEKVQLKRKVTLLRGVSIIIGTIIGAGIFISPKGVLQNTGSVGMSLTIWTVCGVL 89

Query: 91  SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
           S+ GAL YAELGTTI KSG  Y YILE FG   AF+R+WV LL++ P   A+I++ F  Y
Sbjct: 90  SLFGALSYAELGTTIKKSGGHYTYILEVFGPLPAFVRVWVELLIIRPAATAVISLAFGRY 149

Query: 151 IIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMG 210
           I++P F  C+ P LA +L+ A  I ++  +N   V W  R+Q   T+ K+ A++ IIV G
Sbjct: 150 ILEPFFIQCEIPELAIKLITAVGITVVMVLNSMSVSWSARIQIFLTFCKLTAILIIIVPG 209

Query: 211 LVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLA 270
           +++L +G +++F+DAF G    +  L LA Y  +++Y+GW  LNFVTEE++NPE+ +PLA
Sbjct: 210 VMQLIKGQTQNFKDAFSGRDSSITRLPLAFYYGMYAYAGWFYLNFVTEEVENPEKTIPLA 269

Query: 271 IGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFG 330
           I ISM IVT+ Y+LTNVAY+T +N  ++L S+AVAVTF+++  G FS  +PI VALSCFG
Sbjct: 270 ICISMAIVTIGYVLTNVAYFTTINAEELLLSNAVAVTFSERLLGNFSLAVPIFVALSCFG 329

Query: 331 GLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLI 390
            +N  +FA SRLF+V SREGHLP++LSMIH+ + TP+PA++    + +I L   D+  L+
Sbjct: 330 SMNGGVFAVSRLFYVASREGHLPEILSMIHVRKHTPLPAVIVLHPLTMIMLFSGDLDSLL 389

Query: 391 NYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLFTDTIN 450
           N+ SF+ W F+GL+V G +YLR+K P   RP K+ +F P +F    +F+V + L++D  +
Sbjct: 390 NFLSFARWLFIGLAVAGLIYLRYKCPDMHRPFKVPLFIPALFSFTCLFMVALSLYSDPFS 449

Query: 451 SLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503
           + IG  I L+GVP Y++  ++   ++P + R +   ITR T Q+   V+ E D
Sbjct: 450 TGIGFVITLTGVPAYYL--FIIWDKKPRWFRIMSEKITR-TLQIILEVVPEED 499


>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  411 bits (1057), Expect = e-115
 Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)

Query: 18  NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77
           +T   +  ED  S   +  +T  L+KE+ L++G+S++VG +IGSGIFVSPK VL +T + 
Sbjct: 3   DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62

Query: 78  GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137
           G  LI+WA  G+ + +GALC+AELGT ITKSG  Y Y++EA+G   A++  W SL+V++P
Sbjct: 63  GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122

Query: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197
           T  AII ++F+ Y+  P +  C PP +  + LAAA I  ++ VN   V+ G+ VQ+ FT 
Sbjct: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182

Query: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257
           AK+V +  II+ GLV L QG++++F ++FEG+   +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242

Query: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317
           EE++NP RNLPLAI I +P+VT  YIL NV+Y+TV+  +++L S AVAVTF D+     S
Sbjct: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302

Query: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377
           W +P+ VA S  G  N + F + RL +V  REGH+  +LS I + R TP PA++F   +A
Sbjct: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362

Query: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437
            IY+I  D+  L+NYFSF+ W F GL+++G + +R+   +  RP+K+ V  P++  + SV
Sbjct: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422

Query: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470
           FLV+ P+ +  T   L  +   LSG+ FYF+ V+
Sbjct: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456


>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
          Length = 487

 Score =  411 bits (1057), Expect = e-115
 Identities = 201/454 (44%), Positives = 303/454 (66%), Gaps = 1/454 (0%)

Query: 18  NTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASY 77
           +T   +  ED  S   +  +T  L+KE+ L++G+S++VG +IGSGIFVSPK VL +T + 
Sbjct: 3   DTGLRKRREDEKSIQSQEPKTTSLQKELGLISGISIIVGTIIGSGIFVSPKSVLSNTEAV 62

Query: 78  GMSLIVWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEP 137
           G  LI+WA  G+ + +GALC+AELGT ITKSG  Y Y++EA+G   A++  W SL+V++P
Sbjct: 63  GPCLIIWAACGVLATLGALCFAELGTMITKSGGEYPYLMEAYGPIPAYLFSWASLIVIKP 122

Query: 138 TGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTY 197
           T  AII ++F+ Y+  P +  C PP +  + LAAA I  ++ VN   V+ G+ VQ+ FT 
Sbjct: 123 TSFAIICLSFSEYVCAPFYVGCKPPQIVVKCLAAAAILFISTVNSLSVRLGSYVQNIFTA 182

Query: 198 AKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVT 257
           AK+V +  II+ GLV L QG++++F ++FEG+   +G +SLA Y+ L++Y GW+ LN++T
Sbjct: 183 AKLVIVAIIIISGLVLLAQGNTKNFDNSFEGAQLSVGAISLAFYNGLWAYDGWNQLNYIT 242

Query: 258 EEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFS 317
           EE++NP RNLPLAI I +P+VT  YIL NV+Y+TV+  +++L S AVAVTF D+     S
Sbjct: 243 EELRNPYRNLPLAIIIGIPLVTACYILMNVSYFTVMTATELLQSQAVAVTFGDRVLYPAS 302

Query: 318 WTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMA 377
           W +P+ VA S  G  N + F + RL +V  REGH+  +LS I + R TP PA++F   +A
Sbjct: 303 WIVPLFVAFSTIGAANGTCFTAGRLIYVAGREGHMLKVLSYISVRRLTPAPAIIFYGIIA 362

Query: 378 LIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSV 437
            IY+I  D+  L+NYFSF+ W F GL+++G + +R+   +  RP+K+ V  P++  + SV
Sbjct: 363 TIYIIPGDINSLVNYFSFAAWLFYGLTILGLIVMRFTRKELERPIKVPVVIPVLMTLISV 422

Query: 438 FLVIVPLFT-DTINSLIGIGIALSGVPFYFMGVY 470
           FLV+ P+ +  T   L  +   LSG+ FYF+ V+
Sbjct: 423 FLVLAPIISKPTWEYLYCVLFILSGLLFYFLFVH 456


>gi|33286430 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 8 isoform b [Homo
           sapiens]
          Length = 332

 Score =  281 bits (719), Expect = 1e-75
 Identities = 136/300 (45%), Positives = 209/300 (69%), Gaps = 9/300 (3%)

Query: 209 MGLVKLCQGHSEHF----QDAFEG-SSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNP 263
           MG+V++C+G  E+F    ++AFE     D+G ++LA     F+Y GW+ LN+VTEE+ +P
Sbjct: 1   MGIVQICKG--EYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDP 58

Query: 264 ERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIA 323
            +NLP AI IS+P+VT +Y+  NVAY T ++  ++L+S+AVAVTF ++  G+ +W +PI+
Sbjct: 59  YKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPIS 118

Query: 324 VALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIV 383
           VALS FGG+N S+F SSRLFF G+REGHLP +L+MIH++R TPIPALLF C   L+ L+ 
Sbjct: 119 VALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVT 178

Query: 384 EDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVP 443
            D++ LINY  F  + F G++V GQ+ LRWK+P  PRP+K+++ FPI++ +   FL++  
Sbjct: 179 SDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFS 238

Query: 444 LFTDTINSLIGIGIALSGVPFYFMGVYLPESRRPLFIRNVLAAITRGTQQLCFCVLTELD 503
           L+++ +   IG+ I L+GVP YF+GVY     +P    + +  +T  +Q++C  V  E++
Sbjct: 239 LWSEPVVCGIGLAIMLTGVPVYFLGVYW--QHKPKCFSDFIELLTLVSQKMCVVVYPEVE 296


>gi|71999149 solute carrier family 7, (cationic amino acid
           transporter, y+ system) member 13 [Homo sapiens]
          Length = 470

 Score =  261 bits (666), Expect = 1e-69
 Identities = 155/437 (35%), Positives = 248/437 (56%), Gaps = 13/437 (2%)

Query: 37  ETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTA-SYGMSLIVWAIGGLFSVVGA 95
           E +QLK+      G S ++ N+IG+GIFVSPKGVL ++  + G+SL VWA   + ++   
Sbjct: 5   EKIQLKRVFGYWWGTSFLLINIIGAGIFVSPKGVLAYSCMNVGVSLCVWAGCAILAMTST 64

Query: 96  LCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA---ITFANYII 152
           LC AE+  +   SGA Y ++   FG  +AF+ LW SL +    G  ++A   +  A Y I
Sbjct: 65  LCSAEISISFPCSGAQYYFLKRYFGSTVAFLNLWTSLFL----GSGVVAGQALLLAEYSI 120

Query: 153 QPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLV 212
           QP FPSC  P L  + LA A + ++  +    VK  T +Q   +  KV  L  I + G+V
Sbjct: 121 QPFFPSCSVPKLPKKCLALAMLWIVGILTSRGVKEVTWLQIASSVLKVSILSFISLTGVV 180

Query: 213 KLCQGHSEH---FQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPL 269
            L +G  E+   FQ+AF+    D+ +L  A++   F+YSG      +  E+K P   +P 
Sbjct: 181 FLIRGKKENVERFQNAFDAELPDISHLIQAIFQGYFAYSGGACFTLIAGELKKPRTTIPK 240

Query: 270 AIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCF 329
            I  ++P+VT++Y+L N++Y TVL   ++LSSDAVA+T+AD+ F   +W +P A++ S F
Sbjct: 241 CIFTALPLVTVVYLLVNISYLTVLTPREILSSDAVAITWADRAFPSLAWIMPFAISTSLF 300

Query: 330 GGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQL 389
             L  SIF SSR  ++ S+EG LP L + ++    +P  A+L   T+  + +I+  +  L
Sbjct: 301 SNLLISIFKSSRPIYLASQEGQLPLLFNTLN-SHSSPFTAVLLLVTLGSLAIILTSLIDL 359

Query: 390 INYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVFFPIVFCICSVFLVIVPLF-TDT 448
           INY  F+   +  L ++G L  R++EP    P K+ + FP+   +  V LV++PL  +  
Sbjct: 360 INYIFFTGSLWSILLMIGILRRRYQEPNLSIPYKVFLSFPLATIVIDVGLVVIPLVKSPN 419

Query: 449 INSLIGIGIALSGVPFY 465
           ++ +  + + LSG+ FY
Sbjct: 420 VHYVYVLLLVLSGLLFY 436


>gi|110347453 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 4 [Homo sapiens]
          Length = 635

 Score =  105 bits (263), Expect = 8e-23
 Identities = 98/413 (23%), Positives = 186/413 (45%), Gaps = 32/413 (7%)

Query: 31  PPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLF 90
           P + S+    L++ +S L+   L VG M+GSG++V    V    A   + L+ + +  + 
Sbjct: 23  PLEDSTMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGAVAKEVAGPAV-LLSFGVAAVA 81

Query: 91  SVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITFANY 150
           S++ ALCYAE G  + ++G++Y +   + G   AF+  W ++L+    G A +A  ++ Y
Sbjct: 82  SLLAALCYAEFGARVPRTGSAYLFTYVSMGELWAFLIGW-NVLLEYIIGGAAVARAWSGY 140

Query: 151 I-----------IQPSFPSCDPPYLACR--LLAAACICLLTFVNCAYVKWGTRVQD---- 193
           +            +    S   P L      LAA  I L +    A+V  G RV      
Sbjct: 141 LDSMFSHSIRNFTETHVGSWQVPLLGHYPDFLAAGIILLAS----AFVSCGARVSSWLNH 196

Query: 194 TFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMG--NLSLALYSALFSYSGWD 251
           TF+   ++ ++ I+++G + L Q H+     A EG     G   +     S  +++ G+D
Sbjct: 197 TFSAISLLVILFIVILGFI-LAQPHN---WSADEGGFAPFGFSGVMAGTASCFYAFVGFD 252

Query: 252 TLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQ 311
            +   +EE +NP R++PLAI IS+ I    YIL +     ++    +    A+A  F  +
Sbjct: 253 VIAASSEEAQNPRRSVPLAIAISLAIAAGAYILVSTVLTLMVPWHSLDPDSALADAFYQR 312

Query: 312 TFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTPIP-AL 370
            +    + +      +    L + +F+  R+ +  + +G    + + +H     P+   L
Sbjct: 313 GYRWAGFIVAAGSICAMNTVLLSLLFSLPRIVYAMAADGLFFQVFAHVHPRTQVPVAGTL 372

Query: 371 LFNCTMALIYLI--VEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRP 421
            F    A + L+  +E + Q ++  +   + FV  S++   + +   P  P P
Sbjct: 373 AFGLLTAFLALLLDLESLVQFLSLGTLLAYTFVATSIIVLRFQKSSPPSSPGP 425


>gi|4507047 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 1 [Homo sapiens]
          Length = 629

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 97/422 (22%), Positives = 178/422 (42%), Gaps = 43/422 (10%)

Query: 35  SSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVG 94
           S E  +L + ++  + V+L VG+ +G+G++V    V    A   + +I + I  L SV+ 
Sbjct: 22  SREETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAI-VISFLIAALASVLA 80

Query: 95  ALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA----ITFANY 150
            LCY E G  + K+G++Y Y     G   AFI  W +L++    G + +A     TF   
Sbjct: 81  GLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGW-NLILSYIIGTSSVARAWSATFDEL 139

Query: 151 IIQP------SFPSCDPPYLACR---LLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVV 201
           I +P      +  + + P +      + A   I +LT +    VK    V   FT   V+
Sbjct: 140 IGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVL 199

Query: 202 ALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSL----------------------- 238
            L  I+V G VK   G  +++Q   E      G L L                       
Sbjct: 200 VLGFIMVSGFVK---GSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVL 256

Query: 239 -ALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISD 297
               +  +++ G+D +    EE+KNP++ +P+ I  S+ I  + Y   + A   ++    
Sbjct: 257 SGAATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFC 316

Query: 298 VLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLS 357
           + ++  +   F    +    + + +    +    L  S+F   R+ +  + +G L   L+
Sbjct: 317 LDNNSPLPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLA 376

Query: 358 MIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPK 417
            ++    TPI A L +  +A +   + D+  L++  S        L     L LR+ +P+
Sbjct: 377 NVNDRTKTPIIATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRY-QPE 435

Query: 418 RP 419
           +P
Sbjct: 436 QP 437


>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
           sapiens]
          Length = 658

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 96/423 (22%), Positives = 173/423 (40%), Gaps = 54/423 (12%)

Query: 35  SSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVV 93
           S E  +L + +S ++ ++L VG+ +G+G++V    V    A  G S++V + I  L SV+
Sbjct: 24  SLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVM 81

Query: 94  GALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLL-------------------- 133
             LCYAE G  + K+G++Y Y     G   AFI  W  +L                    
Sbjct: 82  AGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEL 141

Query: 134 VVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQD 193
           + +  GQ +      NY     +P            A   I LL  +    VK    V  
Sbjct: 142 LSKQIGQFLRTYFRMNYTGLAEYPD---------FFAVCLILLLAGLLSFGVKESAWVNK 192

Query: 194 TFTYAKVVALIAIIVMGLVKLCQGH---SEHFQDAFEGSSWDMGNLS-LALYSA------ 243
            FT   ++ L+ ++V G VK    +   SE F      S+ +  + +  ++Y A      
Sbjct: 193 VFTAVNILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPY 252

Query: 244 ------------LFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYT 291
                        +++ G+D +    EE++NP++ +P+ I  S+ +  + Y   + A   
Sbjct: 253 GFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTL 312

Query: 292 VLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGH 351
           ++    +     + V F    +G   + +      +    L  SIF   R+ +  + +G 
Sbjct: 313 MMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSIFPMPRVIYAMAEDGL 372

Query: 352 LPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYL 411
           L   L+ I+ +  TPI A L +  +A +   + D+  L++  S        L     L L
Sbjct: 373 LFKCLAQINSKTKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVAACVLIL 432

Query: 412 RWK 414
           R++
Sbjct: 433 RYQ 435


>gi|114326550 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 92/408 (22%), Positives = 173/408 (42%), Gaps = 36/408 (8%)

Query: 40  QLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVVGALCY 98
           +L + +S L+ V+L VG+ +G+G++V    V    A  G S+++ + +  L SV+  LCY
Sbjct: 27  RLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVLAGLCY 84

Query: 99  AELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA----ITFANYI--- 151
           AE G  + +SG++Y Y     G   AF   W +L++    G A +A      F N I   
Sbjct: 85  AEFGARVPRSGSAYLYSYVTVGELWAFTTGW-NLILSYVIGTASVARAWSSAFDNLIGNH 143

Query: 152 ----IQPSFPSCDPPYLA--CRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIA 205
               +Q S     P  LA      A   + LLT +          V   FT   ++ L  
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203

Query: 206 IIVMGLVKLCQGHSEHFQDAFE------GSSWDMGNLSLALY-------------SALFS 246
           +++ G VK    + +  ++ +E        ++ +G L    +             +  ++
Sbjct: 204 VMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYA 263

Query: 247 YSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAV 306
           + G+D +    EE +NP+R++P+ I IS+ +  L Y   + A   ++    +     +  
Sbjct: 264 FVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPE 323

Query: 307 TFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTP 366
            F    +    + + +    +    L  S+F   R+ +  + +G L  +L+ IH    TP
Sbjct: 324 AFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTP 383

Query: 367 IPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
           I A + +  +A     +  +  L++  S        L  +  L LR++
Sbjct: 384 IIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431


>gi|114326544 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 3 [Homo sapiens]
          Length = 619

 Score = 85.5 bits (210), Expect = 1e-16
 Identities = 92/408 (22%), Positives = 173/408 (42%), Gaps = 36/408 (8%)

Query: 40  QLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVVGALCY 98
           +L + +S L+ V+L VG+ +G+G++V    V    A  G S+++ + +  L SV+  LCY
Sbjct: 27  RLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKA--GPSIVICFLVAALSSVLAGLCY 84

Query: 99  AELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIA----ITFANYI--- 151
           AE G  + +SG++Y Y     G   AF   W +L++    G A +A      F N I   
Sbjct: 85  AEFGARVPRSGSAYLYSYVTVGELWAFTTGW-NLILSYVIGTASVARAWSSAFDNLIGNH 143

Query: 152 ----IQPSFPSCDPPYLA--CRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIA 205
               +Q S     P  LA      A   + LLT +          V   FT   ++ L  
Sbjct: 144 ISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGF 203

Query: 206 IIVMGLVKLCQGHSEHFQDAFE------GSSWDMGNLSLALY-------------SALFS 246
           +++ G VK    + +  ++ +E        ++ +G L    +             +  ++
Sbjct: 204 VMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYA 263

Query: 247 YSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAV 306
           + G+D +    EE +NP+R++P+ I IS+ +  L Y   + A   ++    +     +  
Sbjct: 264 FVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPE 323

Query: 307 TFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIERFTP 366
            F    +    + + +    +    L  S+F   R+ +  + +G L  +L+ IH    TP
Sbjct: 324 AFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTP 383

Query: 367 IPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
           I A + +  +A     +  +  L++  S        L  +  L LR++
Sbjct: 384 IIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQ 431


>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
           sapiens]
          Length = 697

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 94/423 (22%), Positives = 173/423 (40%), Gaps = 55/423 (13%)

Query: 35  SSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV-WAIGGLFSVV 93
           S E  +L + +S ++ ++L VG+ +G+G++V    V    A  G S++V + I  L SV+
Sbjct: 64  SLEDTKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVA--KADSGPSIVVSFLIAALASVM 121

Query: 94  GALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLL-------------------- 133
             LCYAE G  + K+G++Y Y     G   AFI  W  +L                    
Sbjct: 122 AGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDEL 181

Query: 134 VVEPTGQAIIAITFANYIIQPSFPSCDPPYLACRLLAAACICLLTFVNCAYVKWGTRVQD 193
           + +  GQ +      NY     +P            A   I LL  +    VK    V  
Sbjct: 182 LSKQIGQFLRTYFRMNYTGLAEYPD---------FFAVCLILLLAGLLSFGVKESAWVNK 232

Query: 194 TFTYAKVVALIAIIVMGLVKLCQGH---SEHFQDAFEGSSWDMGNLS-LALYSA------ 243
            FT   ++ L+ ++V G VK    +   SE F      S+ +  + +  ++Y A      
Sbjct: 233 VFTAVNILVLLFVMVAGFVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPY 292

Query: 244 ------------LFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYT 291
                        +++ G+D +    EE++NP++ +P+ I  S+ +  + Y   + A   
Sbjct: 293 GFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTL 352

Query: 292 VLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGH 351
           ++    +     + V F    +G   + +      +    L  S+F   R+ F  +R+G 
Sbjct: 353 MMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGL 412

Query: 352 LPDLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYL 411
           L   L+ +  +R +P+ A L    ++ +   + D+  L++  S        L     L L
Sbjct: 413 LFRFLARVS-KRQSPVAATLTAGVISALMAFLFDLKALVDMMSIGTLMAYSLVAACVLIL 471

Query: 412 RWK 414
           R++
Sbjct: 472 RYQ 474


>gi|181337167 solute carrier family 7 (cationic amino acid
           transporter, y+ system), member 14 [Homo sapiens]
          Length = 771

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 86/415 (20%), Positives = 167/415 (40%), Gaps = 38/415 (9%)

Query: 24  VEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLVHTASYGMSLIV 83
           VE  +      ++   +L + ++ ++ +SL VG+ +G+G++V    V    A  G+ ++ 
Sbjct: 32  VESMLEGTGTTTAHGTKLAQVLTTVDLISLGVGSCVGTGMYVVSGLVAKEMAGPGV-IVS 90

Query: 84  WAIGGLFSVVGALCYAELGTTITKS-GASYAYILEAFGGFIAFIRLW---VSLLVVEPTG 139
           + I  + S++  +CYAE G  + K+ G++Y Y     G F+AF   W   +  L+    G
Sbjct: 91  FIIAAVASILSGVCYAEFGVRVPKTTGSAYTYSYVTVGEFVAFFIGWNLILEYLIGTAAG 150

Query: 140 QAIIAITF---ANYII-----------------QPSFPSCDPPYLACRLLAAACICLLTF 179
            + ++  F   AN+ I                 + S+P          LLA     ++T 
Sbjct: 151 ASALSSMFDSLANHTISRWMADSVGTLNGLGKGEESYPD---------LLALLIAVIVTI 201

Query: 180 VNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMGNLSLA 239
           +    VK      +      +   + I++ GL  +   +    Q    G S  +   +  
Sbjct: 202 IVALGVKNSIGFNNVLNVLNLAVWVFIMIAGLFFINGKYWAEGQFLPHGWSGVLQGAATC 261

Query: 240 LYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVL 299
            Y+    + G+D +    EE KNP  ++P AI  S+ I    Y+  +V    ++    + 
Sbjct: 262 FYA----FIGFDIIATTGEEAKNPNTSIPYAITASLVICLTAYVSVSVILTLMVPYYTID 317

Query: 300 SSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLFFVGSREGHLPDLLSMI 359
           +   +   F    F    + + I         L  S+F   R+ +  + +G L   L+ +
Sbjct: 318 TESPLMEMFVAHGFYAAKFVVAIGSVAGLTVSLLGSLFPMPRVIYAMAGDGLLFRFLAHV 377

Query: 360 HIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWK 414
                TP+ A + +  +A +  ++  +  LI   S        L  V  L LR++
Sbjct: 378 SSYTETPVVACIVSGFLAALLALLVSLRDLIEMMSIGTLLAYTLVSVCVLLLRYQ 432


>gi|198041678 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 1139

 Score = 36.2 bits (82), Expect = 0.074
 Identities = 41/193 (21%), Positives = 83/193 (43%), Gaps = 15/193 (7%)

Query: 259 EIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSW 318
           ++++ ++++P    +++   + +YI + V +   +    VL          +   G  +W
Sbjct: 446 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIE-GVVLRDKFGEAVNGNLVVGTLAW 504

Query: 319 TIPIAVAL-----SCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIE-RFTPIPALLF 372
             P  + +     +C  GL  S+  + RL    SR+G +P L    H +    P  ALL 
Sbjct: 505 PSPWVIVIGSFFSTCGAGLQ-SLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLL 563

Query: 373 N---CTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLR---WKEPKRPRPLKLSV 426
               C + ++   +++V  +++ F    + FV L+   Q  LR   W+   R     LS 
Sbjct: 564 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS- 622

Query: 427 FFPIVFCICSVFL 439
           F  +  C+  +F+
Sbjct: 623 FLGMSLCLALMFI 635


>gi|11968148 solute carrier family 12 (potassium-chloride
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 1116

 Score = 36.2 bits (82), Expect = 0.074
 Identities = 41/193 (21%), Positives = 83/193 (43%), Gaps = 15/193 (7%)

Query: 259 EIKNPERNLPLAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSW 318
           ++++ ++++P    +++   + +YI + V +   +    VL          +   G  +W
Sbjct: 423 DLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIE-GVVLRDKFGEAVNGNLVVGTLAW 481

Query: 319 TIPIAVAL-----SCFGGLNASIFASSRLFFVGSREGHLPDLLSMIHIE-RFTPIPALLF 372
             P  + +     +C  GL  S+  + RL    SR+G +P L    H +    P  ALL 
Sbjct: 482 PSPWVIVIGSFFSTCGAGLQ-SLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLL 540

Query: 373 N---CTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLR---WKEPKRPRPLKLSV 426
               C + ++   +++V  +++ F    + FV L+   Q  LR   W+   R     LS 
Sbjct: 541 TACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLS- 599

Query: 427 FFPIVFCICSVFL 439
           F  +  C+  +F+
Sbjct: 600 FLGMSLCLALMFI 612


>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
          Length = 714

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 46/235 (19%), Positives = 92/235 (39%), Gaps = 23/235 (9%)

Query: 165 ACRLLAAACICLLTFVNCAYVKWGTRVQDTFTYAKVVALIAIIVMGLVKLCQ-----GHS 219
           A R ++ A +  L  +N A VKW  R+Q    +   V+ +  +V     L       G+S
Sbjct: 156 AVRGISVAVLLALLGINLAGVKWIIRLQLLLLFLLAVSTLDFVVGSFTHLDPEHGFIGYS 215

Query: 220 EHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNF-VTEEIKNPERNLPL----AIGIS 274
                      +  G     ++   F  +      F +  +++ P  ++PL    A+GIS
Sbjct: 216 PELLQNNTLPDYSPGESFFTVFGVFFPAATGVMAGFNMGGDLREPAASIPLGSLAAVGIS 275

Query: 275 MPI-VTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLN 333
             + +  +++L  +     L    +++     + F      +F   + I+   SC GGL 
Sbjct: 276 WFLYIVFVFLLGAICTREALRYDFLIAEKVSLMGF------LFLLGLYISSLASCMGGL- 328

Query: 334 ASIFASSRLFFVGSREGHLPDL--LSMIHIERFTPIPALLFNCTMALIYLIVEDV 386
              + + R+    ++E  +P L  L        TP+ A+     + + ++ V  V
Sbjct: 329 ---YGAPRILQCIAQEKVIPALACLGQGKGPNKTPVAAICLTSLVTMAFVFVGQV 380


>gi|194239643 activating transcription factor 7 isoform 3 [Homo
           sapiens]
          Length = 462

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 16/66 (24%), Positives = 31/66 (46%)

Query: 4   REPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGI 63
           R+ G PT +  LV + +  Q    +  PP +    + L + +S++  +  + G  + S  
Sbjct: 163 RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSG 222

Query: 64  FVSPKG 69
            +SP G
Sbjct: 223 SISPSG 228


>gi|5802980 activating transcription factor 7 isoform 2 [Homo
           sapiens]
          Length = 483

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 16/66 (24%), Positives = 31/66 (46%)

Query: 4   REPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGI 63
           R+ G PT +  LV + +  Q    +  PP +    + L + +S++  +  + G  + S  
Sbjct: 184 RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSG 243

Query: 64  FVSPKG 69
            +SP G
Sbjct: 244 SISPSG 249


>gi|194239640 activating transcription factor 7 isoform 1 [Homo
           sapiens]
          Length = 494

 Score = 31.6 bits (70), Expect = 1.8
 Identities = 16/66 (24%), Positives = 31/66 (46%)

Query: 4   REPGRPTPTYHLVPNTSQSQVEEDVSSPPQRSSETMQLKKEISLLNGVSLVVGNMIGSGI 63
           R+ G PT +  LV + +  Q    +  PP +    + L + +S++  +  + G  + S  
Sbjct: 195 RQMGSPTGSLPLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPNIPGIPGPPVNSSG 254

Query: 64  FVSPKG 69
            +SP G
Sbjct: 255 SISPSG 260


>gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]
          Length = 570

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 34/133 (25%), Positives = 56/133 (42%), Gaps = 27/133 (20%)

Query: 168 LLAAACICLLTFVNCAYVKWGTRVQD----TFTYAKVVALIAIIVMGL--------VKLC 215
           +L   C  LL+F+  +     TRV+       T+ K+VA +  +   +        V+ C
Sbjct: 67  ILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWC 126

Query: 216 QGHSEHFQDAFEGSSWDMGNLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAI---- 271
                +  D +  +  ++G+     Y           LNF  + IKNPE  L LA+    
Sbjct: 127 VNARVNNSDPYSVALSELGDRQNESY-----------LNFARKRIKNPEGGLYLAVTLLA 175

Query: 272 GISMPIVTLIYIL 284
           GI+  ++TL  IL
Sbjct: 176 GITGVVITLCLIL 188


>gi|47933348 zinc finger, DHHC domain containing 13 isoform 2 [Homo
           sapiens]
          Length = 492

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 371 LFNCTMALIYLIVEDVFQLINY---FSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVF 427
           L  C + L+ ++       I Y   F+   W   G  +V   +L    P+     K  V+
Sbjct: 157 LQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVY 216

Query: 428 FPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVY 470
            P  F + SVF + +  F       I     L+G PFYF  ++
Sbjct: 217 LPTAFLLSSVFWIFMTWF-------ILFFPDLAGAPFYFSFIF 252


>gi|47933346 zinc finger, DHHC domain containing 13 isoform 1 [Homo
           sapiens]
          Length = 622

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 371 LFNCTMALIYLIVEDVFQLINY---FSFSYWFFVGLSVVGQLYLRWKEPKRPRPLKLSVF 427
           L  C + L+ ++       I Y   F+   W   G  +V   +L    P+     K  V+
Sbjct: 287 LQKCELFLLLMLSVITMWAIGYILDFNSDSWLLKGCLLVTLFFLTSLFPRFLVGYKNLVY 346

Query: 428 FPIVFCICSVFLVIVPLFTDTINSLIGIGIALSGVPFYFMGVY 470
            P  F + SVF + +  F       I     L+G PFYF  ++
Sbjct: 347 LPTAFLLSSVFWIFMTWF-------ILFFPDLAGAPFYFSFIF 382


>gi|6912726 transmembrane 4 superfamily member 16 [Homo sapiens]
          Length = 245

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 29/108 (26%), Positives = 46/108 (42%), Gaps = 7/108 (6%)

Query: 41  LKKEISLLNGVSLVVG-NMIGSGIFVSPKGVLVHTASYGMSLIVWAIGGLFSVVGALCYA 99
           LKK +SLLNG   V G  ++G GI     G  +       S  +  +G L  V+G +   
Sbjct: 11  LKKLLSLLNGFVAVSGIILVGLGIGGKCGGASLTNVLGLSSAYLLHVGNLCLVMGCI--- 67

Query: 100 ELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLVVEPTGQAIIAITF 147
              T +      Y    E+ G  +  I   V +L++E T   ++ + F
Sbjct: 68  ---TVLLGCAGWYGATKESRGTLLFCILSMVIVLIMEVTAATVVLLFF 112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.141    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,686,983
Number of Sequences: 37866
Number of extensions: 803739
Number of successful extensions: 2701
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2631
Number of HSP's gapped (non-prelim): 41
length of query: 515
length of database: 18,247,518
effective HSP length: 107
effective length of query: 408
effective length of database: 14,195,856
effective search space: 5791909248
effective search space used: 5791909248
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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