Guide to the Human Genome
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Search of human proteins with 23510348

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23510348 TRAF and TNF receptor-associated protein [Homo
sapiens]
         (362 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23510348 TRAF and TNF receptor-associated protein [Homo sapiens]   737   0.0  
gi|31083028 CCR4 carbon catabolite repression 4-like [Homo sapiens]    40   0.003
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]           32   0.89 
gi|29568099 p47 protein isoform b [Homo sapiens]                       31   1.5  
gi|20149635 p47 protein isoform a [Homo sapiens]                       31   1.5  
gi|239754510 PREDICTED: similar to hCG1644697 [Homo sapiens]           31   2.0  
gi|239749071 PREDICTED: similar to hCG1644697 [Homo sapiens]           31   2.0  
gi|239743097 PREDICTED: similar to hCG1644697 [Homo sapiens]           31   2.0  
gi|239508749 PREDICTED: similar to hCG1644697 [Homo sapiens]           31   2.0  
gi|224591404 cancer/testis antigen family 147, member B1 [Homo s...    30   2.6  
gi|32698954 hypothetical protein LOC283991 [Homo sapiens]              30   4.4  
gi|40217820 slit and trk like 3 protein [Homo sapiens]                 30   4.4  
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ...    29   5.7  
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]        28   9.8  
gi|4504653 interleukin 18 proprotein [Homo sapiens]                    28   9.8  
gi|23097338 neurexophilin 1 precursor [Homo sapiens]                   28   9.8  
gi|155723000 mixed lineage kinase 4 [Homo sapiens]                     28   9.8  
gi|11968023 zinc finger protein 106 homolog [Homo sapiens]             28   9.8  

>gi|23510348 TRAF and TNF receptor-associated protein [Homo sapiens]
          Length = 362

 Score =  737 bits (1902), Expect = 0.0
 Identities = 362/362 (100%), Positives = 362/362 (100%)

Query: 1   MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNS 60
           MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNS
Sbjct: 1   MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNS 60

Query: 61  YFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWN 120
           YFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWN
Sbjct: 61  YFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWN 120

Query: 121 IDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFT 180
           IDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFT
Sbjct: 121 IDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFT 180

Query: 181 AIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQ 240
           AIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQ
Sbjct: 181 AIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNELCLMTSHLESTRGHAAERMNQ 240

Query: 241 LKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQ 300
           LKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQ
Sbjct: 241 LKMVLKKMQEAPESATVIFAGDTNLRDREVTRCGGLPNNIVDVWEFLGKPKHCQYTWDTQ 300

Query: 301 MNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDI 360
           MNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDI
Sbjct: 301 MNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLLGLEKLDCGRFPSDHWGLLCNLDI 360

Query: 361 IL 362
           IL
Sbjct: 361 IL 362


>gi|31083028 CCR4 carbon catabolite repression 4-like [Homo sapiens]
          Length = 431

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 57/256 (22%), Positives = 100/256 (39%), Gaps = 38/256 (14%)

Query: 131 ERARGVCSYLALYSPDVIFLQEV------IPPYYSYLKKRSSNYE------IITGHEEGY 178
           ER   +   +  Y PD++ LQEV        P  S L  + + +       +   H  G 
Sbjct: 174 ERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGP 233

Query: 179 F-TAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNV----SGNELCLMTSHLESTRGH 233
              A+   ++R KL +   I   +  +  N + +   +    SG + C+  +HL++  G 
Sbjct: 234 DGCALFFLQNRFKLVNSANIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTGW 293

Query: 234 AAERMNQLKMVLKKMQEAPESATV--IFAGDTNLRDRE--VTRCGGLPNNIVDVWEFL-- 287
              R  Q   +L+ +Q   + A +  I  GD N    E           N+   ++ L  
Sbjct: 294 ERFRSAQGCDLLQNLQNITQGAKIPLIVCGDFNAEPTEEVYKHFASSSLNLNSAYKLLSA 353

Query: 288 -GKPKHCQYTWDTQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLL-----GLEK 341
            G+ +    TW       +  +  C+   D I++   A     +  +LDLL     G  +
Sbjct: 354 DGQSEPPYTTW------KIRTSGECRHTLDYIWYSKHALN---VRSALDLLTEEQIGPNR 404

Query: 342 LDCGRFPSDHWGLLCN 357
           L    +PSDH  L+C+
Sbjct: 405 LPSFNYPSDHLSLVCD 420


>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
          Length = 3565

 Score = 32.0 bits (71), Expect = 0.89
 Identities = 18/77 (23%), Positives = 39/77 (50%), Gaps = 9/77 (11%)

Query: 284  WEFLGKPKHCQYTWD------TQMNSNLGITAACKLRFDRIFFRAAAEEGHIIPRSLDLL 337
            +E+LGK +    T D      +++N+     +  +L+   I+ +   EE H++ ++  + 
Sbjct: 3363 YEYLGKRQPATLTVDWFNATSSKVNATFSEASPVELKLTGIYKK---EEAHLLLKAFQIK 3419

Query: 338  GLEKLDCGRFPSDHWGL 354
            G   +   +F +D+WGL
Sbjct: 3420 GQADIFVSKFENDNWGL 3436


>gi|29568099 p47 protein isoform b [Homo sapiens]
          Length = 339

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 20/84 (23%), Positives = 34/84 (40%)

Query: 31  EFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNE 90
           EF +V   +   A+ FL    W+++ AL S++E   +E  +     T S        ++ 
Sbjct: 11  EFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDN 70

Query: 91  ETTDSTTSKISPSEDTQQENGSMF 114
             T          ED ++E G  F
Sbjct: 71  RVTSFRDLIHDQDEDEEEEEGQRF 94


>gi|20149635 p47 protein isoform a [Homo sapiens]
          Length = 370

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 20/84 (23%), Positives = 34/84 (40%)

Query: 31  EFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLTNE 90
           EF +V   +   A+ FL    W+++ AL S++E   +E  +     T S        ++ 
Sbjct: 11  EFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDN 70

Query: 91  ETTDSTTSKISPSEDTQQENGSMF 114
             T          ED ++E G  F
Sbjct: 71  RVTSFRDLIHDQDEDEEEEEGQRF 94


>gi|239754510 PREDICTED: similar to hCG1644697 [Homo sapiens]
          Length = 194

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 4   GSCLEGGREAAEEEGEPEVKKRRLLCVEFASV--ASCDAAVAQCFLAENDWE 53
           GS L G R+    EG P   +RR  C +  +V  +SC  A  + F  E  WE
Sbjct: 75  GSRLTGERKGVGTEGHPGFYERRHQCKQSVNVQISSCALAALRSFPIELGWE 126


>gi|239749071 PREDICTED: similar to hCG1644697 [Homo sapiens]
          Length = 194

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 4   GSCLEGGREAAEEEGEPEVKKRRLLCVEFASV--ASCDAAVAQCFLAENDWE 53
           GS L G R+    EG P   +RR  C +  +V  +SC  A  + F  E  WE
Sbjct: 75  GSRLTGERKGVGTEGHPGFYERRHQCKQSVNVQISSCALAALRSFPIELGWE 126


>gi|239743097 PREDICTED: similar to hCG1644697 [Homo sapiens]
          Length = 194

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 4   GSCLEGGREAAEEEGEPEVKKRRLLCVEFASV--ASCDAAVAQCFLAENDWE 53
           GS L G R+    EG P   +RR  C +  +V  +SC  A  + F  E  WE
Sbjct: 75  GSRLTGERKGVGTEGHPGFYERRHQCKQSVNVQISSCALAALRSFPIELGWE 126


>gi|239508749 PREDICTED: similar to hCG1644697 [Homo sapiens]
          Length = 194

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 2/52 (3%)

Query: 4   GSCLEGGREAAEEEGEPEVKKRRLLCVEFASV--ASCDAAVAQCFLAENDWE 53
           GS L G R+    EG P   +RR  C +  +V  +SC  A  + F  E  WE
Sbjct: 75  GSRLTGERKGVGTEGHPGFYERRHQCKQSVNVQISSCALAALRSFPIELGWE 126


>gi|224591404 cancer/testis antigen family 147, member B1 [Homo
           sapiens]
          Length = 299

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 65  PVEESALERRPETISEPKTYVDLTNEETTDSTTSK--ISPSEDTQQE 109
           P EE+A E+ PE  +E K   + T E   +  TS+  ++P E T+ +
Sbjct: 218 PAEEAADEKPPEEAAEEKLTEEATEEPAAEEPTSEEAVAPEEVTKSQ 264


>gi|32698954 hypothetical protein LOC283991 [Homo sapiens]
          Length = 164

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 20/90 (22%), Positives = 36/90 (40%)

Query: 24  KRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKT 83
           + +++  +F   A C A  A+  L    W+ E AL+++F+     ++        +   T
Sbjct: 9   RHQVMINQFVLAAGCAADQAKQLLQAAHWQFETALSTFFQETNIPNSHHHHQMMCTPSNT 68

Query: 84  YVDLTNEETTDSTTSKISPSEDTQQENGSM 113
                N     +  SK+  SE  Q  N  M
Sbjct: 69  PATPPNFPDALAMFSKLRASEGLQSSNSPM 98


>gi|40217820 slit and trk like 3 protein [Homo sapiens]
          Length = 977

 Score = 29.6 bits (65), Expect = 4.4
 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%)

Query: 161 LKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTKMMRNLLCVHVNVSGNEL 220
           L+   ++Y +I   E G F    L K RV + +  +IP   T + + +   H+++ GN L
Sbjct: 151 LEYLQADYNVIKRIESGAFRN--LSKLRVLILNDNLIPMLPTNLFKAVSLTHLDLRGNRL 208


>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
            sapiens]
          Length = 3258

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 8/86 (9%)

Query: 125  DLNNLSERARGVCSYLALYSPD-------VIFLQEVIPPYYSYLKKRSSNYEII-TGHEE 176
            DL      A  +C  +  Y+P+       ++ L+ ++P Y   LK+++S  E +    EE
Sbjct: 2338 DLTFSISEAIKLCVTVVAYAPESFRSLQMLMVLEALVPCYLQKLKRQTSQVETVPAAREE 2397

Query: 177  GYFTAIMLKKSRVKLKSQEIIPFPST 202
               TA +    +  L S E++  P T
Sbjct: 2398 IAATAALATSLQALLYSVEVLTRPMT 2423


>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
          Length = 506

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 8/53 (15%)

Query: 58  LNSYFEPPVEESALERRPETISEPKTYVDLTNEETTDSTTSKISPSEDTQQEN 110
           +N+ +EP  EE       E  S        ++EE  D+T S++ P E  ++EN
Sbjct: 151 INAEYEPTEEECEWNSEDEEFS--------SDEEVQDNTPSEMPPLEGEEEEN 195


>gi|4504653 interleukin 18 proprotein [Homo sapiens]
          Length = 193

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 42/178 (23%), Positives = 76/178 (42%), Gaps = 30/178 (16%)

Query: 29  CVEFASVASCDAAVAQCFLAENDWEMERALNSYFEPPVEESALERRPETISEPKTYVDLT 88
           C+ F ++   D  +   F+AE+D  +E   + YF     + ++ R    +++   ++D  
Sbjct: 10  CINFVAMKFIDNTLY--FIAEDDENLE---SDYFGKLESKLSVIRN---LNDQVLFIDQG 61

Query: 89  N----EETTDS--------TTSKISPSEDTQQENGSM-FSLITWNIDGLDLNN--LSERA 133
           N    E+ TDS        T   IS  +D+Q    ++  S+    I  L   N  +S + 
Sbjct: 62  NRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKE 121

Query: 134 RGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKL 191
                 +     D+IF Q  +P + + ++  SS+Y       EGYF A   ++   KL
Sbjct: 122 MNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSY-------EGYFLACEKERDLFKL 172


>gi|23097338 neurexophilin 1 precursor [Homo sapiens]
          Length = 271

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 10/68 (14%)

Query: 90  EETTDSTTSKISPSEDTQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIF 149
           ++ T +T     PS+   QE     S ++W          S+  + +C Y++ YS D   
Sbjct: 202 DKATKNTLCNYDPSKTCYQEQTQ--SHVSWLC--------SKPFKVICIYISFYSTDYKL 251

Query: 150 LQEVIPPY 157
           +Q+V P Y
Sbjct: 252 VQKVCPDY 259


>gi|155723000 mixed lineage kinase 4 [Homo sapiens]
          Length = 1036

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 32/142 (22%), Positives = 56/142 (39%), Gaps = 6/142 (4%)

Query: 63  EPPVEESALE-RRPETISEP-KTYVDLTNEETTDSTTSKISPSEDTQQENGSMFSLITWN 120
           EP +    LE R+P+ I  P + Y+DL           + +P+E    E  +  +  T +
Sbjct: 646 EPKLSPDGLEHRKPKQIKLPSQAYIDLP----LGKDAQRENPAEAESWEEAASANAATVS 701

Query: 121 IDGLDLNNLSERARGVCSYLALYSPDVIFLQEVIPPYYSYLKKRSSNYEIITGHEEGYFT 180
           I+    N+LS   +   +  ALY   V+     +      L K  +  E +   E+    
Sbjct: 702 IEMTPTNSLSRSPQRKKTESALYGCTVLLASVALGLDLRELHKAQAAEEPLPKEEKKKRE 761

Query: 181 AIMLKKSRVKLKSQEIIPFPST 202
            I  + S+ +  +      PST
Sbjct: 762 GIFQRASKSRRSASPPTSLPST 783


>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
          Length = 1883

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 19/81 (23%), Positives = 38/81 (46%)

Query: 1   MELGSCLEGGREAAEEEGEPEVKKRRLLCVEFASVASCDAAVAQCFLAENDWEMERALNS 60
           +E+   ++  +EA + +GEP++        E  S++S      +  L+E+   M+RA + 
Sbjct: 814 IEMVPLVQNEQEALDLDGEPDLSSLEGFQWEGVSISSSPGLARKRSLSESSVIMDRAPSV 873

Query: 61  YFEPPVEESALERRPETISEP 81
           Y     E +  E  P+ +  P
Sbjct: 874 YSFFSEEGTGKENEPQQMVSP 894


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,263,213
Number of Sequences: 37866
Number of extensions: 603058
Number of successful extensions: 1704
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1697
Number of HSP's gapped (non-prelim): 21
length of query: 362
length of database: 18,247,518
effective HSP length: 104
effective length of query: 258
effective length of database: 14,309,454
effective search space: 3691839132
effective search space used: 3691839132
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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