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Search of human proteins with 23510340
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
(1058 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] 2133 0.0
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] 2133 0.0
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa... 862 0.0
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] 757 0.0
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 158 2e-38
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 123 1e-27
gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 121 4e-27
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] 117 6e-26
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 117 6e-26
gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s... 108 2e-23
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s... 108 2e-23
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ... 79 2e-14
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 71 5e-12
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] 69 2e-11
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] 52 3e-06
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] 52 3e-06
gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo... 39 0.026
gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens] 34 0.83
gi|34577105 RNA-binding region containing protein 1 isoform b [H... 32 2.4
gi|34577107 RNA-binding region containing protein 1 isoform a [H... 32 2.4
>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 2133 bits (5526), Expect = 0.0
Identities = 1058/1058 (100%), Positives = 1058/1058 (100%)
Query: 1 MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLY 60
MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLY
Sbjct: 1 MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLY 60
Query: 61 VLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLRE 120
VLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLRE
Sbjct: 61 VLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLRE 120
Query: 121 EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCH 180
EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCH
Sbjct: 121 EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCH 180
Query: 181 NRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH 240
NRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH
Sbjct: 181 NRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH 240
Query: 241 GFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK 300
GFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK
Sbjct: 241 GFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK 300
Query: 301 ISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVA 360
ISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVA
Sbjct: 301 ISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVA 360
Query: 361 LAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI 420
LAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI
Sbjct: 361 LAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI 420
Query: 421 MQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIG 480
MQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIG
Sbjct: 421 MQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIG 480
Query: 481 CELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN 540
CELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN
Sbjct: 481 CELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN 540
Query: 541 PHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGT 600
PHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGT
Sbjct: 541 PHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGT 600
Query: 601 LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA 660
LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA
Sbjct: 601 LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA 660
Query: 661 ENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSN 720
ENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSN
Sbjct: 661 ENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSN 720
Query: 721 NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTG 780
NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTG
Sbjct: 721 NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTG 780
Query: 781 SQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP 840
SQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP
Sbjct: 781 SQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP 840
Query: 841 GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAA 900
GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAA
Sbjct: 841 GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAA 900
Query: 901 VVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV 960
VVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV
Sbjct: 901 VVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV 960
Query: 961 QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS 1020
QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS
Sbjct: 961 QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS 1020
Query: 1021 RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR 1058
RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
Sbjct: 1021 RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR 1058
>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 2133 bits (5526), Expect = 0.0
Identities = 1058/1058 (100%), Positives = 1058/1058 (100%)
Query: 1 MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLY 60
MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLY
Sbjct: 1 MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYSRQLY 60
Query: 61 VLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLRE 120
VLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLRE
Sbjct: 61 VLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLRE 120
Query: 121 EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCH 180
EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCH
Sbjct: 121 EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPLEDQLRVGEFCH 180
Query: 181 NRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH 240
NRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH
Sbjct: 181 NRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH 240
Query: 241 GFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK 300
GFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK
Sbjct: 241 GFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK 300
Query: 301 ISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVA 360
ISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVA
Sbjct: 301 ISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVA 360
Query: 361 LAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI 420
LAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI
Sbjct: 361 LAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI 420
Query: 421 MQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIG 480
MQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIG
Sbjct: 421 MQWLYFDALECLPEDKEVLTEDKCLQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIG 480
Query: 481 CELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN 540
CELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN
Sbjct: 481 CELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN 540
Query: 541 PHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGT 600
PHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGT
Sbjct: 541 PHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGT 600
Query: 601 LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA 660
LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA
Sbjct: 601 LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA 660
Query: 661 ENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSN 720
ENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSN
Sbjct: 661 ENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWADCVTWACHHWHTQYSN 720
Query: 721 NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTG 780
NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTG
Sbjct: 721 NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNPLHLDYVMAAANLFAQTYGLTG 780
Query: 781 SQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP 840
SQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP
Sbjct: 781 SQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP 840
Query: 841 GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAA 900
GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAA
Sbjct: 841 GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAA 900
Query: 901 VVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV 960
VVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV
Sbjct: 901 VVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV 960
Query: 961 QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS 1020
QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS
Sbjct: 961 QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS 1020
Query: 1021 RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR 1058
RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
Sbjct: 1021 RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR 1058
>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
sapiens]
Length = 1012
Score = 862 bits (2228), Expect = 0.0
Identities = 474/1018 (46%), Positives = 644/1018 (63%), Gaps = 25/1018 (2%)
Query: 50 IDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQW 109
+DE LYSRQLYVLG AM+R+Q + VLVSGL+GLG E+AKN++L GV ++TLHD W
Sbjct: 10 LDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCW 69
Query: 110 ADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPL 169
+DL++QF L E+D+ ++RAE SQ LA+LN V V +TG + ED L FQVVVLT L
Sbjct: 70 SDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKL 129
Query: 170 EDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNP 229
E+QL+VG CH G+ + ADTRGL GQLFCDFGE+ + D +PL+A + +++ +P
Sbjct: 130 EEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSP 189
Query: 230 GVVTCLDEAR-HGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIR 288
G++T A H F GD V+FS ++GMVELN P I V + I DT+ FS Y+R
Sbjct: 190 GILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLR 249
Query: 289 GGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPR 348
GG +++VK PK + KSL +L +P V + LH F ALH+F HGRPP+
Sbjct: 250 GGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQ 309
Query: 349 PRNEEDAAELVALAQAVN--ARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAA 406
P + DA +V LA+ + R + LDE L+R +A +AG L+P+ A +G +AA
Sbjct: 310 PWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAA 369
Query: 407 QEVMKACSGKFMPIMQWLYFDALECLPEDKEVL-TEDKCLQRQNRYDGQVAVFGSDLQEK 465
QEV+KA S KFMP+ QWLYFDAL+CLPED E+L + + C R +RYDGQ+AVFG+ QEK
Sbjct: 370 QEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEK 429
Query: 466 LGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVT 525
L +Q Y LVGAGAIGCELLK FA++GLG G G + V DMD IE+SNL+RQFLFR DV
Sbjct: 430 LRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVG 489
Query: 526 KLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMD 585
+ K++ AAAA R +NP ++V + P TE IY D+FF +DGVA ALD+ AR Y+
Sbjct: 490 RPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVA 549
Query: 586 RRCVYYRKPLLESGTLGTKGNVQVVIPFLTESY------SSSQDPPEKSIPICTLKNFPN 639
RC +Y KPLLE+GT GT G+ V +P +TE+Y ++S+D P P+CT++ FP+
Sbjct: 550 ARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAP---YPVCTVRYFPS 606
Query: 640 AIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQR 699
EHTLQWAR EFE LF+ AE +N + + + Q L +L+ V ++ R
Sbjct: 607 TAEHTLQWARHEFEELFRLSAETINHH---QQAHTSLADMDEPQTLTLLKPV-LGVLRVR 662
Query: 700 PQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNP 759
PQ W DCV WA HW + I+QLL +FPP+++ G PFWSGPK+CP PL FD N
Sbjct: 663 PQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQD 722
Query: 760 LHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANA 819
HL YV+AAANL+AQ +GL GSQD A+ L+ + P+ P+ I S+ EL SA+A
Sbjct: 723 THLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPD--PQQMAPIFASNLELASASA 780
Query: 820 SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSAD 879
+ +EL L P K P+ FEKDDDSNFH+DF+VAA++LR +NY IP +
Sbjct: 781 EFGPEQQKELNKALEVWSVGPPLK--PLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVN 838
Query: 880 RHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEP 939
R +SK I G+IIPAIATTTAAV GL+ LELYKVV G R ++++ +L+LA + P
Sbjct: 839 RAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMP 898
Query: 940 LAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYS 999
A +++ +WT WDR +V QP E TL+ L + + +H L + +L G ++LY+
Sbjct: 899 FAPAIQTFHHLKWTSWDRLKVPAGQP---ERTLESLLAHLQEQHGLRVRILLHGSALLYA 955
Query: 1000 FFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057
K + L +TE+V +++ + R LVLEL C + ED P + Y +
Sbjct: 956 AGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDD-EDTAFPPLHYEL 1012
>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
Length = 1052
Score = 757 bits (1955), Expect = 0.0
Identities = 436/1033 (42%), Positives = 626/1033 (60%), Gaps = 45/1033 (4%)
Query: 46 SEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQG 105
+ +ID+ LYSRQ YVLG AM+++ S V +SG+ GLG+EIAKN++L G+KAVT+HD
Sbjct: 35 ASVEIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTE 94
Query: 106 TAQWADLSSQFYLREEDI--GKNRAEVSQPRLAELNSYVPVTAYTGPLVE----DFLSGF 159
Q DL + F+L E+D+ +NRAE +AELN YV VT+ + P E FL +
Sbjct: 95 KCQAWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKY 154
Query: 160 QVVVLTNTPLEDQLRVGEFCHNR--GIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPL 217
Q VVLT L Q ++ +FC ++ IK + AD G++ +LFCDFG+E + D+ GE+P
Sbjct: 155 QCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPK 214
Query: 218 SAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSI 277
+S +T+ NPG+VTCL+ H E+G F++F E+ GM LNG+ +I V+ P++FSI
Sbjct: 215 EIFISNITQANPGIVTCLENHPHKLETGQFLTFREINGMTGLNGSI-QQITVISPFSFSI 273
Query: 278 CDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALH 337
DT+ Y+ GGI QVK PK + F+SL L P ++ DF+ P ++H AL
Sbjct: 274 GDTTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLALD 333
Query: 338 QFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPI 397
QF ++ R P ++D+ EL+ LA +++ ++ +++ D++ L++ A G L+P+
Sbjct: 334 QFQEKYSRKPNVGCQQDSEELLKLATSISETL---EEKPDVNADIVHWLSWTAQGFLSPL 390
Query: 398 NAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKEVLTEDKC---LQRQNRYDGQ 454
A +GG+A+QEV+KA +GKF P+ QWLY +A + + E L + +C L R +RYD
Sbjct: 391 AAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIV----ESLGKPECEEFLPRGDRYDAL 446
Query: 455 VAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCG-EGGEIIVTDMDTIEKSNL 513
A G L +KL FLVG GAIGCE+LKNFA++G+G E G I VTD D IEKSNL
Sbjct: 447 RACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSNL 506
Query: 514 NRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVAN 573
NRQFLFRP + K KS TAA A ++N I++ +H N+V P TE IY+D+F+ D +
Sbjct: 507 NRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVIIT 566
Query: 574 ALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICT 633
ALDNV+AR Y+D RC+ +PLL+SGT+GTKG+ +V++P LTESY+S +DPPE+ IP CT
Sbjct: 567 ALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEEIPFCT 626
Query: 634 LKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTL-RLAGTQPLEVLEAVQ 692
LK+FP AIEHT+QWARD+FE F N++ E L ++ LE V
Sbjct: 627 LKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSAEEVLQKIQSGHSLEGCFQVI 686
Query: 693 RSLVLQRPQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPL 752
+ L+ +RP+ W+ CV A + +++ QLLH FP D G+ FW PKR P P+
Sbjct: 687 K-LLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRPPSPI 745
Query: 753 TFDVNNPLHLDYVMAAANLFAQTYGLTGSQD---RAAVATFLQSVQVPEFTPKSGVKIHV 809
FD+N PLHL ++ AA L+A Y + +++ A+ L V++ EF P + K+
Sbjct: 746 KFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKPSN--KVVQ 803
Query: 810 SDQELQSAN---ASVDDSR---LEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIV 863
+D+ + + S +D R + KA L + +M + FEKDDD N H+DFI
Sbjct: 804 TDETARKPDHVPISSEDERNAIFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHIDFIT 863
Query: 864 AASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYK 923
AASNLRA+ Y I ADR K+K IAGKIIPAIATTTA V GLV LE+ KV G+ ++YK
Sbjct: 864 AASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKVTGGY-PFEAYK 922
Query: 924 NGFLNLALPFFGFSEPLAAPRHQYYNQ-EWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTE 982
N FLNLA+P F+E + + N +T+WDR+ V G E+ TL F++ K +
Sbjct: 923 NCFLNLAIPIVVFTETTEVRKTKIRNGISFTIWDRWTVHG----KEDFTLLDFINAVKEK 978
Query: 983 HKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCND 1042
+ +E TM+ QGV MLY MP +RL M ++V +++K L + +
Sbjct: 979 YGIEPTMVVQGVKMLYVPVMPGH--AKRLKLTMHKLVKPTTEKK----YVDLTVSFAPDI 1032
Query: 1043 ESGEDVEVPYVRY 1055
+ ED+ P VRY
Sbjct: 1033 DGDEDLPGPPVRY 1045
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 158 bits (400), Expect = 2e-38
Identities = 149/477 (31%), Positives = 227/477 (47%), Gaps = 76/477 (15%)
Query: 461 DLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFR 520
+L E + + +VGAG IGCELLKN + G I + D+DTI+ SNLNRQFLF+
Sbjct: 10 ELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFS-----HIDLIDLDTIDVSNLNRQFLFQ 64
Query: 521 PWDVTKLKSDTAAAAVRQMNPHIRVTS-HQNRVGPDTERIYDDDFFQNLDGVANALDNVD 579
V + K+ A +V Q P + + H + + PD Y+ +FF+ V NALDN
Sbjct: 65 KKHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPD----YNVEFFRQFILVMNALDNRA 120
Query: 580 ARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPN 639
AR +++R C+ PL+ESGT G G V + +TE Y P +++ P CT++N P+
Sbjct: 121 ARNHVNRMCLAADVPLIESGTAGYLGQVTTIKKGVTECYECHPKPTQRTFPGCTIRNTPS 180
Query: 640 AIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEV---LEAVQRSLV 696
H + WA+ F LF + E+ +Q ++ +R A +P E A
Sbjct: 181 EPIHCIVWAKYLFNQLFGE--EDADQEVSP----DRADPEAAWEPTEAEARARASNEDGD 234
Query: 697 LQRPQT--WADCVTWACHHWHTQ-YSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLT 753
++R T WA + T+ + ++IR LL D+L W KR P
Sbjct: 235 IKRISTKEWAKSTGYDPVKLFTKLFKDDIRYLL---TMDKL-------WR--KRKP---- 278
Query: 754 FDVNNPLHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQE 813
P+ LD+ SQ A+ Q+ P+ G+K DQ+
Sbjct: 279 -----PVPLDWAEVQ------------SQGEETNASDQQN------EPQLGLK----DQQ 311
Query: 814 LQSAN--ASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAE 871
+ A + +E L+ L +K G ++ ++KDD S MDF+ +A+NLR
Sbjct: 312 VLDVKSYARLFSKSIETLRVHL--AEKGDGAELI---WDKDDPS--AMDFVTSAANLRMH 364
Query: 872 NYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLN 928
+ + R K +AG IIPAIATT A + GL+ LE K++ G ++D + FLN
Sbjct: 365 IFSMNMKSRFDIKSMAGNIIPAIATTNAVIAGLIVLEGLKILSG--KIDQCRTIFLN 419
Score = 54.7 bits (130), Expect = 5e-07
Identities = 35/142 (24%), Positives = 71/142 (50%), Gaps = 5/142 (3%)
Query: 62 LGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREE 121
L E + + VLV G G+G E+ KN++L G + L D T ++L+ QF +++
Sbjct: 7 LPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKK 66
Query: 122 DIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE-DF-LSGFQVVVLTNTPLEDQL---RVG 176
+G+++A+V++ + + + AY ++ D+ + F+ +L L+++ V
Sbjct: 67 HVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVN 126
Query: 177 EFCHNRGIKLVVADTRGLFGQL 198
C + L+ + T G GQ+
Sbjct: 127 RMCLAADVPLIESGTAGYLGQV 148
>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 123 bits (308), Expect = 1e-27
Identities = 104/389 (26%), Positives = 162/389 (41%), Gaps = 65/389 (16%)
Query: 45 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104
G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D
Sbjct: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
Query: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161
D +QF +R +G+NRAE S R LN V V T + E F + F
Sbjct: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
Query: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221
V LT + ++V + CH IK D G G F + GE + +
Sbjct: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEE---------- 178
Query: 222 SMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTS 281
T + + HG E G +++ D+S
Sbjct: 179 -----------TDVAKVSHGVEDGPDTKRAKL-------------------------DSS 202
Query: 282 NFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCA 341
+ + + VK ++ + S A A R + Q L +F
Sbjct: 203 ETTMVKKKVVFCPVKEALEVDWSSEKAK-----------AALKRTTSDYFLLQVLLKFRT 251
Query: 342 QHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFI 401
GR P E+ +EL+ + +L + + L ED +R ++AP+ A +
Sbjct: 252 DKGRDPSSDTYEEDSELLLQIRNDVLDSL-GISPDLLPEDFVR----YCFSEMAPVCAVV 306
Query: 402 GGLAAQEVMKACSGKFMPIMQWLYFDALE 430
GG+ AQE++KA S + P + +FD ++
Sbjct: 307 GGILAQEIVKALSQRDPPHNNFFFFDGMK 335
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
+YD Q+ ++G + Q++L + LVG +G E+ KN + G+ + + D + +
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
Query: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567
+ QFL R V + +++ + + +NP + V DTE I + FF
Sbjct: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
Query: 568 LDGVANALDNVDARMYMDRRC 588
D V + D + +D+ C
Sbjct: 126 FDAVCLTCCSRDVIVKVDQIC 146
>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 121 bits (303), Expect = 4e-27
Identities = 105/389 (26%), Positives = 158/389 (40%), Gaps = 65/389 (16%)
Query: 45 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104
G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D
Sbjct: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
Query: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLV---EDFLSGFQV 161
D +QF +R +G+NRAE S R LN V V T + E F + F
Sbjct: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
Query: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221
V LT + ++V + CH IK D G G F + GE + +
Sbjct: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEK---------- 178
Query: 222 SMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTS 281
+ V K + GV D R +S +
Sbjct: 179 TKVAKVSQGVEDGPDTKRAKLDSSE----------------------------------- 203
Query: 282 NFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCA 341
V KK+ F + +L A R + Q L +F
Sbjct: 204 ------------TTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDYFLLQVLLKFRT 251
Query: 342 QHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFI 401
GR P E+ +EL+ + +L + + L ED +R ++AP+ A +
Sbjct: 252 DKGRDPSSDTYEEDSELLLQIRNDVLDSL-GISPDLLPEDFVR----YCFSEMAPVCAVV 306
Query: 402 GGLAAQEVMKACSGKFMPIMQWLYFDALE 430
GG+ AQE++KA S + P + +FD ++
Sbjct: 307 GGILAQEIVKALSQRDPPHNNFFFFDGMK 335
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
+YD Q+ ++G + Q++L + LVG +G E+ KN + G+ + + D + +
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
Query: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567
+ QFL R V + +++ + + +NP + V DTE I + FF
Sbjct: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
Query: 568 LDGVANALDNVDARMYMDRRC 588
D V + D + +D+ C
Sbjct: 126 FDAVCLTCCSRDVIVKVDQIC 146
>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
Length = 449
Score = 117 bits (293), Expect = 6e-26
Identities = 68/202 (33%), Positives = 110/202 (54%), Gaps = 24/202 (11%)
Query: 462 LQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRP 521
LQ L K ++GAG +GCELLKN A+ G +I V DMDTI+ SNLNRQFLFRP
Sbjct: 49 LQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRP 103
Query: 522 WDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDAR 581
D+ + K++ AA + P+ V H N++ + ++D F++ + LD++ AR
Sbjct: 104 KDIGRPKAEVAAEFLNDRVPNCNVVPHFNKI-----QDFNDTFYRQFHIIVCGLDSIIAR 158
Query: 582 MYMDRRCVYYRK------------PLLESGTLGTKGNVQVVIPFLTESYSSSQD--PPEK 627
+++ + PL++ GT G KGN +V++P +T + + PP+
Sbjct: 159 RWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQV 218
Query: 628 SIPICTLKNFPNAIEHTLQWAR 649
+ P+CT+ + P EH +++ R
Sbjct: 219 NFPMCTIASMPRLPEHCIEYVR 240
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/75 (42%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 70 LQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAE 129
L T VLV G GLG E+ KN+ L G + + + D T ++L+ QF R +DIG+ +AE
Sbjct: 53 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 112
Query: 130 VSQPRLAE-LNSYVP 143
V+ AE LN VP
Sbjct: 113 VA----AEFLNDRVP 123
Score = 37.4 bits (85), Expect = 0.075
Identities = 18/61 (29%), Positives = 32/61 (52%)
Query: 852 DDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYK 911
D D H+ +I S RA Y+I ++ + +IIPA+A+T A + + E++K
Sbjct: 257 DGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFK 316
Query: 912 V 912
+
Sbjct: 317 I 317
>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
Length = 463
Score = 117 bits (293), Expect = 6e-26
Identities = 68/202 (33%), Positives = 110/202 (54%), Gaps = 24/202 (11%)
Query: 462 LQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRP 521
LQ L K ++GAG +GCELLKN A+ G +I V DMDTI+ SNLNRQFLFRP
Sbjct: 63 LQFLLDTCKVLVIGAGGLGCELLKNLALSGFR-----QIHVIDMDTIDVSNLNRQFLFRP 117
Query: 522 WDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDAR 581
D+ + K++ AA + P+ V H N++ + ++D F++ + LD++ AR
Sbjct: 118 KDIGRPKAEVAAEFLNDRVPNCNVVPHFNKI-----QDFNDTFYRQFHIIVCGLDSIIAR 172
Query: 582 MYMDRRCVYYRK------------PLLESGTLGTKGNVQVVIPFLTESYSSSQD--PPEK 627
+++ + PL++ GT G KGN +V++P +T + + PP+
Sbjct: 173 RWINGMLISLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQV 232
Query: 628 SIPICTLKNFPNAIEHTLQWAR 649
+ P+CT+ + P EH +++ R
Sbjct: 233 NFPMCTIASMPRLPEHCIEYVR 254
Score = 52.0 bits (123), Expect = 3e-06
Identities = 32/75 (42%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 70 LQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAE 129
L T VLV G GLG E+ KN+ L G + + + D T ++L+ QF R +DIG+ +AE
Sbjct: 67 LDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAE 126
Query: 130 VSQPRLAE-LNSYVP 143
V+ AE LN VP
Sbjct: 127 VA----AEFLNDRVP 137
Score = 37.4 bits (85), Expect = 0.075
Identities = 18/61 (29%), Positives = 32/61 (52%)
Query: 852 DDDSNFHMDFIVAASNLRAENYDIPSADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYK 911
D D H+ +I S RA Y+I ++ + +IIPA+A+T A + + E++K
Sbjct: 271 DGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFK 330
Query: 912 V 912
+
Sbjct: 331 I 331
>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
sapiens]
Length = 266
Score = 108 bits (271), Expect = 2e-23
Identities = 69/188 (36%), Positives = 94/188 (50%), Gaps = 7/188 (3%)
Query: 45 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104
G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D
Sbjct: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
Query: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161
D +QF +R +G+NRAE S R LN V V T + E F + F
Sbjct: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
Query: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221
V LT + ++V + CH IK D G G F + GE + E+ A V
Sbjct: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE----EKTKVAKV 184
Query: 222 SMVTKDNP 229
S +D P
Sbjct: 185 SQGVEDGP 192
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
+YD Q+ ++G + Q++L + LVG +G E+ KN + G+ + + D + +
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
Query: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567
+ QFL R V + +++ + + +NP + V DTE I + FF
Sbjct: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
Query: 568 LDGVANALDNVDARMYMDRRC 588
D V + D + +D+ C
Sbjct: 126 FDAVCLTCCSRDVIVKVDQIC 146
>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
sapiens]
Length = 299
Score = 108 bits (271), Expect = 2e-23
Identities = 69/188 (36%), Positives = 94/188 (50%), Gaps = 7/188 (3%)
Query: 45 GSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQ 104
G ++ + Y RQ+ + G EA KRL+ S VL+ GL+GLG EIAKN+IL GVK +T+ D
Sbjct: 9 GGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDH 68
Query: 105 GTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPL---VEDFLSGFQV 161
D +QF +R +G+NRAE S R LN V V T + E F + F
Sbjct: 69 EQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDA 128
Query: 162 VVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMV 221
V LT + ++V + CH IK D G G F + GE + E+ A V
Sbjct: 129 VCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVE----EKTKVAKV 184
Query: 222 SMVTKDNP 229
S +D P
Sbjct: 185 SQGVEDGP 192
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/141 (24%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 450 RYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIE 509
+YD Q+ ++G + Q++L + LVG +G E+ KN + G+ + + D + +
Sbjct: 18 QYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV-----KGLTMLDHEQVT 72
Query: 510 KSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERI--YDDDFFQN 567
+ QFL R V + +++ + + +NP + V DTE I + FF
Sbjct: 73 PEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVK-------VDTEDIEKKPESFFTQ 125
Query: 568 LDGVANALDNVDARMYMDRRC 588
D V + D + +D+ C
Sbjct: 126 FDAVCLTCCSRDVIVKVDQIC 146
>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
sapiens]
Length = 534
Score = 79.0 bits (193), Expect = 2e-14
Identities = 52/160 (32%), Positives = 75/160 (46%), Gaps = 16/160 (10%)
Query: 50 IDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQW 109
+ E Y RQL + G + L+++ V + G EI KN++L G+ + T+ D
Sbjct: 8 LKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSG 67
Query: 110 ADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSG 158
D + F+L+ IGKNRAE + L ELNS V +G VE+ F
Sbjct: 68 EDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCR 122
Query: 159 FQVVVLTNTPLEDQLRVGEFCHNRGIKLVVADTRGLFGQL 198
F VVV T P LR+ + N I L++ T GL G +
Sbjct: 123 FTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYM 162
Score = 45.8 bits (107), Expect = 2e-04
Identities = 46/212 (21%), Positives = 87/212 (41%), Gaps = 16/212 (7%)
Query: 445 LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTD 504
L ++ +YD Q+ ++G QE L L+ A A G E+LKN + G+ G + D
Sbjct: 7 LLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIID 61
Query: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDD- 563
+ + + F + + K +++ A ++++N + + V E + D+D
Sbjct: 62 GNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV----SGSFVEESPENLLDNDP 117
Query: 564 -FFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQ 622
FF V + + + PLL T G G ++++I + + +
Sbjct: 118 SFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIII----KEHPVIE 173
Query: 623 DPPEKSIPICTL-KNFPNAIEHTLQWARDEFE 653
P+ ++ L K FP EH + D E
Sbjct: 174 SHPDNALEDLRLDKPFPELREHFQSYDLDHME 205
Score = 38.9 bits (89), Expect = 0.026
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 312 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 371
Query: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 372 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 424
Query: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 425 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 474
Query: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 475 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 514
>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
sapiens]
Length = 528
Score = 71.2 bits (173), Expect = 5e-12
Identities = 47/147 (31%), Positives = 68/147 (46%), Gaps = 16/147 (10%)
Query: 63 GHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREED 122
G + L+++ V + G EI KN++L G+ + T+ D D + F+L+
Sbjct: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
Query: 123 IGKNRAEVSQPRLAELNSYVPVTAYTGPLVED-----------FLSGFQVVVLTNTPLED 171
IGKNRAE + L ELNS V +G VE+ F F VVV T P
Sbjct: 75 IGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
Query: 172 QLRVGEFCHNRGIKLVVADTRGLFGQL 198
LR+ + N I L++ T GL G +
Sbjct: 130 SLRLADVLWNSQIPLLICRTYGLVGYM 156
Score = 38.9 bits (89), Expect = 0.026
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 306 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 365
Query: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 366 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 418
Query: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 419 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 468
Query: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 469 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 508
Score = 37.7 bits (86), Expect = 0.058
Identities = 43/212 (20%), Positives = 82/212 (38%), Gaps = 16/212 (7%)
Query: 445 LQRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTD 504
+ Q + ++G QE L L+ A A G E+LKN + G+ G + D
Sbjct: 1 MDAQQTKTNEARLWGDHGQEALESAHVCLINATATGTEILKNLVLPGI-----GSFTIID 55
Query: 505 MDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDD- 563
+ + + F + + K +++ A ++++N + + V E + D+D
Sbjct: 56 GNQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV----SGSFVEESPENLLDNDP 111
Query: 564 -FFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQ 622
FF V + + + PLL T G G ++++I + + +
Sbjct: 112 SFFCRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYMRIII----KEHPVIE 167
Query: 623 DPPEKSIPICTL-KNFPNAIEHTLQWARDEFE 653
P+ ++ L K FP EH + D E
Sbjct: 168 SHPDNALEDLRLDKPFPELREHFQSYDLDHME 199
>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
Length = 460
Score = 69.3 bits (168), Expect = 2e-11
Identities = 52/176 (29%), Positives = 83/176 (47%), Gaps = 15/176 (8%)
Query: 436 KEVLTEDKCLQRQNRYDGQVAV--FGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLG 493
K L+ D+ L RY Q+ + G Q +LG +VG G +GC L + A G+G
Sbjct: 52 KAALSRDEIL----RYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVG 107
Query: 494 CGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPHIRVTSHQNRVG 553
+ + D D +E SNL RQ L + K+ +AAA++R++N + + +
Sbjct: 108 -----RLGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALT 162
Query: 554 PDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQV 609
P T D + D VA+ DNV R ++ CV +PL+ + L +G + V
Sbjct: 163 PATAL----DLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITV 214
Score = 51.2 bits (121), Expect = 5e-06
Identities = 45/150 (30%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 55 YSRQLYV--LGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADL 112
YSRQL + LG RL T+ VL+ G GLG +A+ + GV + L D + ++L
Sbjct: 63 YSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNL 122
Query: 113 SSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVE----DFLSGFQVVVLTNTP 168
+ Q E G+ +A + L LNS V YT L D + + VV +
Sbjct: 123 ARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYDVVADCSDN 182
Query: 169 LEDQLRVGEFCHNRGIKLVVADTRGLFGQL 198
+ + V + C G LV A GQ+
Sbjct: 183 VPTRYLVNDACVLAGRPLVSASALRFEGQI 212
>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]
Length = 348
Score = 52.0 bits (123), Expect = 3e-06
Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 16/159 (10%)
Query: 464 EKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWD 523
EK+ +VG G +G + G+G ++++ D D +E +N+NR F F+P
Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIG-----KLLLFDYDKVELANMNRLF-FQPHQ 66
Query: 524 VTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQN--------LDGVANAL 575
K A +R +NP + H + + D N +D V + +
Sbjct: 67 AGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCV 126
Query: 576 DNVDARMYMDRRCVYYRKPLLESGTL--GTKGNVQVVIP 612
DN +ARM ++ C + +ESG G++Q++IP
Sbjct: 127 DNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIP 165
>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
Length = 404
Score = 52.0 bits (123), Expect = 3e-06
Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 16/159 (10%)
Query: 464 EKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWD 523
EK+ +VG G +G + G+G ++++ D D +E +N+NR F F+P
Sbjct: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIG-----KLLLFDYDKVELANMNRLF-FQPHQ 122
Query: 524 VTKLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQN--------LDGVANAL 575
K A +R +NP + H + + D N +D V + +
Sbjct: 123 AGLSKVQAAEHTLRNINPDVLFEVHNYNITTVENFQHFMDRISNGGLEEGKPVDLVLSCV 182
Query: 576 DNVDARMYMDRRCVYYRKPLLESGTL--GTKGNVQVVIP 612
DN +ARM ++ C + +ESG G++Q++IP
Sbjct: 183 DNFEARMTINTACNELGQTWMESGVSENAVSGHIQLIIP 221
>gi|66363688 NEDD8 activating enzyme E1 subunit 1 isoform c [Homo
sapiens]
Length = 445
Score = 38.9 bits (89), Expect = 0.026
Identities = 42/220 (19%), Positives = 87/220 (39%), Gaps = 22/220 (10%)
Query: 204 EEMILTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMVELNGNQ 263
+E + + G P+ + + D+ + + R + + V +++ G
Sbjct: 223 KEFVAKEGQGNLPVRGTIPDMIADSGKYIKLQNVYREKAKKDAAAVGNHVAKLLQSIGQA 282
Query: 264 P-----MEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLVASLAEPDFVVT 318
P E+K+L C S F +R +++ I+ +++S+ PD +
Sbjct: 283 PESISEKELKLL-------CSNSAFLRVVRCRSLAEEYGLDTINKDEIISSMDNPDNEIV 335
Query: 319 DFAKFSRPAQLHIGFQALHQFCAQHGRPPRPRNEEDAAELVALAQAVNARALPAVQQNNL 378
L++ +A+ +F Q GR P N + ++ L + +
Sbjct: 336 ----------LYLMLRAVDRFHKQQGRYPGVSNYQVEEDIGKLKSCLTGFLQEYGLSVMV 385
Query: 379 DEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFM 418
+D + + A + I AF+GG AAQEV+K + +F+
Sbjct: 386 KDDYVHEFCRYGAAEPHTIAAFLGGAAAQEVIKIITKQFV 425
>gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]
Length = 584
Score = 33.9 bits (76), Expect = 0.83
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 8 KKRRVSG--PDPKPGSNCSPAQSVLSEVPSVPTNGMAKNGSEADIDEGLYS 56
+K RV G PDP PG+ +P P NG K+ + D DE + S
Sbjct: 499 RKPRVRGGAPDPSPGATATPGAPAQPSSPDARRNGQEKHFKDEDEDEDVAS 549
>gi|34577105 RNA-binding region containing protein 1 isoform b [Homo
sapiens]
Length = 121
Score = 32.3 bits (72), Expect = 2.4
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 932 PFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYF-KTEHKLEITML 990
P GF PLAAP + +Q+ T + + V GL + + +L+++ + F E + IT
Sbjct: 10 PSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDR 69
Query: 991 SQGVSMLYSF 1000
G S Y F
Sbjct: 70 QTGKSRGYGF 79
>gi|34577107 RNA-binding region containing protein 1 isoform a [Homo
sapiens]
Length = 239
Score = 32.3 bits (72), Expect = 2.4
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 932 PFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYF-KTEHKLEITML 990
P GF PLAAP + +Q+ T + + V GL + + +L+++ + F E + IT
Sbjct: 10 PSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDR 69
Query: 991 SQGVSMLYSF 1000
G S Y F
Sbjct: 70 QTGKSRGYGF 79
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,626,394
Number of Sequences: 37866
Number of extensions: 1843062
Number of successful extensions: 4558
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 4471
Number of HSP's gapped (non-prelim): 42
length of query: 1058
length of database: 18,247,518
effective HSP length: 113
effective length of query: 945
effective length of database: 13,968,660
effective search space: 13200383700
effective search space used: 13200383700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.