Guide to the Human Genome
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Search of human proteins with 23238236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
isoform 3 [Homo sapiens]
         (178 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ...   345   9e-96
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ...   282   1e-76
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ...   282   1e-76
gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E ...    94   6e-20
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i...    90   9e-19
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i...    90   9e-19
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [...    72   3e-13
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [...    69   3e-12
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15...    63   1e-10
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    58   4e-09
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i...    57   8e-09
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i...    57   8e-09
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A...    55   2e-08
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A...    55   2e-08
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A...    55   2e-08
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ...    52   4e-07
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is...    52   4e-07
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ...    51   5e-07
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [...    50   1e-06
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [...    50   1e-06
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    48   5e-06
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ...    47   7e-06
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ...    42   4e-04
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ...    42   4e-04
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ...    42   4e-04
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10...    36   0.020
gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 i...    33   0.099
gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 i...    33   0.099
gi|166795252 hypothetical protein LOC23359 [Homo sapiens]              33   0.13 
gi|24308237 phosphatidylinositol transfer protein, membrane-asso...    32   0.38 

>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 3 [Homo sapiens]
          Length = 178

 Score =  345 bits (886), Expect = 9e-96
 Identities = 178/178 (100%), Positives = 178/178 (100%)

Query: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
           MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60

Query: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
           SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120

Query: 121 SILSALSALVGFIILSVKQATLNPASLQWNSLSDADLHSAGILPSCAHCCAAVETGLL 178
           SILSALSALVGFIILSVKQATLNPASLQWNSLSDADLHSAGILPSCAHCCAAVETGLL
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQWNSLSDADLHSAGILPSCAHCCAAVETGLL 178


>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 2 [Homo sapiens]
          Length = 225

 Score =  282 bits (721), Expect = 1e-76
 Identities = 148/148 (100%), Positives = 148/148 (100%)

Query: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
           MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60

Query: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
           SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120

Query: 121 SILSALSALVGFIILSVKQATLNPASLQ 148
           SILSALSALVGFIILSVKQATLNPASLQ
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQ 148


>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 1 [Homo sapiens]
          Length = 248

 Score =  282 bits (721), Expect = 1e-76
 Identities = 148/148 (100%), Positives = 148/148 (100%)

Query: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
           MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL
Sbjct: 1   MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60

Query: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120
           SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG
Sbjct: 61  SLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVG 120

Query: 121 SILSALSALVGFIILSVKQATLNPASLQ 148
           SILSALSALVGFIILSVKQATLNPASLQ
Sbjct: 121 SILSALSALVGFIILSVKQATLNPASLQ 148


>gi|21264311 membrane-spanning 4-domains, subfamily A, member 6E
          [Homo sapiens]
          Length = 147

 Score = 94.0 bits (232), Expect = 6e-20
 Identities = 47/74 (63%), Positives = 56/74 (75%)

Query: 1  MTSQPVPNETIIVLPSNVINFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVL 60
          MTSQP+ NETII+LPSNVINFSQAEKPEPTNQGQDSLKK L A++KVIG    L G ++ 
Sbjct: 1  MTSQPISNETIIMLPSNVINFSQAEKPEPTNQGQDSLKKRLQAKVKVIGVHSSLAGSILS 60

Query: 61 SLGIILASASFSPN 74
          +L  ++     S N
Sbjct: 61 ALSALVGFILLSVN 74



 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 32/49 (65%), Positives = 37/49 (75%)

Query: 100 SLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQ 148
           SL    + ++  + VHSSL GSILSALSALVGFI+LSV  A LNPASLQ
Sbjct: 36  SLKKRLQAKVKVIGVHSSLAGSILSALSALVGFILLSVNPAALNPASLQ 84


>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 90.1 bits (222), Expect = 9e-19
 Identities = 54/136 (39%), Positives = 74/136 (54%)

Query: 19  INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78
           I   Q EKP    Q +D L+  L  E  V+GT+QILC +++ SLG IL  A +  +F   
Sbjct: 19  ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78

Query: 79  TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138
            ST L S YPF+G   F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+  
Sbjct: 79  ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138

Query: 139 QATLNPASLQWNSLSD 154
              L  AS    S  D
Sbjct: 139 MVALRTASQHCGSEMD 154


>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 90.1 bits (222), Expect = 9e-19
 Identities = 54/136 (39%), Positives = 74/136 (54%)

Query: 19  INFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV 78
           I   Q EKP    Q +D L+  L  E  V+GT+QILC +++ SLG IL  A +  +F   
Sbjct: 19  ITIPQREKPGHMYQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFAPYPSHFNPA 78

Query: 79  TSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVK 138
            ST L S YPF+G   F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+  
Sbjct: 79  ISTTLMSGYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADS 138

Query: 139 QATLNPASLQWNSLSD 154
              L  AS    S  D
Sbjct: 139 MVALRTASQHCGSEMD 154


>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
           [Homo sapiens]
          Length = 267

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 43/97 (44%), Positives = 60/97 (61%), Gaps = 5/97 (5%)

Query: 44  EIKVIGTIQILCGMMVLSLGIILASASFSPNFTQV---TSTLLNSAYPFIGPFFFIISGS 100
           E K +G IQI+ G+M +  GI+L   SFS  F +V    ST +   YPF G   FIISGS
Sbjct: 87  EAKALGVIQIMVGLMHIGFGIVLCLISFS--FREVLGFASTAVIGGYPFWGGLSFIISGS 144

Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
           LS++  K L++ LV  SL  +I+S++ A +G I+L V
Sbjct: 145 LSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLV 181


>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
           [Homo sapiens]
          Length = 200

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 4/138 (2%)

Query: 1   MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM 58
           M S    +   +V P  +    +   E    T   Q  L+K    ++K++GTIQIL G+M
Sbjct: 1   MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60

Query: 59  VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL 118
             S G+I       P + +     L S YPF G   FI SG+  IA +++ T+ L+  S 
Sbjct: 61  TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR 118

Query: 119 VGSILSALSALVGFIILS 136
           + + LSAL A+ G I+L+
Sbjct: 119 IMNFLSALGAIAGIILLT 136


>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 47/131 (35%), Positives = 64/131 (48%), Gaps = 9/131 (6%)

Query: 10  TIIVLPSNVINFSQ----AEKPEPTNQGQ-DSLKKHLHAEIKVIGTIQILCGMMVLSLGI 64
           T +  P  ++ F +    A+ P  T       ++  L  E KV+GT+QIL G++ L  G 
Sbjct: 31  TSMCQPPGIMQFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLGFGS 90

Query: 65  ILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILS 124
           +L           V    +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS
Sbjct: 91  VLLMVRRG----HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILS 146

Query: 125 ALSALVGFIIL 135
            ++A  G  IL
Sbjct: 147 VMAAFAGTAIL 157


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 58.2 bits (139), Expect = 4e-09
 Identities = 46/157 (29%), Positives = 72/157 (45%), Gaps = 13/157 (8%)

Query: 27  PEPTN----QGQDSLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQ-VTST 81
           PE  N    Q  D    +  A+++V+G IQIL   M+L+LG+ L S  +  +F +     
Sbjct: 26  PEELNTSVYQPIDGSPDYQKAKLQVLGAIQILNAAMILALGVFLGSLQYPYHFQKHFFFF 85

Query: 82  LLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQAT 141
              + YP  G  FF  SG+LS+    + T+  + +S   +I SA  ALVG   LS+  A 
Sbjct: 86  TFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAV 145

Query: 142 LNPASLQWNSLSDADLHSAGILPSCAHCCAAVETGLL 178
                   N  S    HS+   P   +   ++  G++
Sbjct: 146 --------NIQSLRSCHSSSESPDLCNYMGSISNGMV 174


>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
           isoform a [Homo sapiens]
          Length = 220

 Score = 57.0 bits (136), Expect = 8e-09
 Identities = 39/97 (40%), Positives = 53/97 (54%), Gaps = 2/97 (2%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFII 97
           +K L  E KV+G +QIL  +M LS+GI +   + +   +   S  +   Y   G   FII
Sbjct: 37  EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIG--YTIWGSVMFII 94

Query: 98  SGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFII 134
           SGSLSIA   R TK LV  SL  +I S++ A  G +I
Sbjct: 95  SGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILI 131


>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
           isoform b [Homo sapiens]
          Length = 239

 Score = 57.0 bits (136), Expect = 8e-09
 Identities = 39/97 (40%), Positives = 53/97 (54%), Gaps = 2/97 (2%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFII 97
           +K L  E KV+G +QIL  +M LS+GI +   + +   +   S  +   Y   G   FII
Sbjct: 56  EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIG--YTIWGSVMFII 113

Query: 98  SGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFII 134
           SGSLSIA   R TK LV  SL  +I S++ A  G +I
Sbjct: 114 SGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILI 150


>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 1 [Homo sapiens]
          Length = 243

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 12/105 (11%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
           +K    + KV+G ++IL  +M LS+GII+   +FS     P F  V       AY   G 
Sbjct: 60  EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112

Query: 93  FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
             FIIS SLS+A   R TK LV  SL  +I S++ A+ G +I ++
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAI 157


>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 12/105 (11%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
           +K    + KV+G ++IL  +M LS+GII+   +FS     P F  V       AY   G 
Sbjct: 60  EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112

Query: 93  FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
             FIIS SLS+A   R TK LV  SL  +I S++ A+ G +I ++
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAI 157


>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 12/105 (11%)

Query: 38  KKHLHAEIKVIGTIQILCGMMVLSLGIILASASFS-----PNFTQVTSTLLNSAYPFIGP 92
           +K    + KV+G ++IL  +M LS+GII+   +FS     P F  V       AY   G 
Sbjct: 60  EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYV-------AYTIWGS 112

Query: 93  FFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
             FIIS SLS+A   R TK LV  SL  +I S++ A+ G +I ++
Sbjct: 113 VMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAI 157


>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%)

Query: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113

Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
           LSI +E+R    LV  SL  +  S+++   G  IL +
Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150


>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
           isoform 1 [Homo sapiens]
          Length = 244

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 32/97 (32%), Positives = 47/97 (48%)

Query: 41  LHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGS 100
           L  E + +G  QIL  M+ L  G ++ S     +      +   + YPF G  FF ISG 
Sbjct: 54  LKKEQEFLGVTQILTAMICLCFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGM 113

Query: 101 LSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSV 137
           LSI +E+R    LV  SL  +  S+++   G  IL +
Sbjct: 114 LSIISERRNATYLVRGSLGANTASSIAGGTGITILII 150


>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
           [Homo sapiens]
          Length = 250

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 34/92 (36%), Positives = 52/92 (56%), Gaps = 5/92 (5%)

Query: 44  EIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSI 103
           E K +G IQI+ G+  + LG I+A+        +  S      +PF G  +FIISGSLS+
Sbjct: 68  EGKTLGAIQIIIGLAHIGLGSIMATVLVG----EYLSISFYGGFPFWGGLWFIISGSLSV 123

Query: 104 ATEKR-LTKLLVHSSLVGSILSALSALVGFII 134
           A E +  +  L+  SL  +I+SA+ + VG I+
Sbjct: 124 AAENQPYSYCLLSGSLGLNIVSAICSAVGVIL 155


>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 9/93 (9%)

Query: 44  EIKVIGTIQILCGMMVLSLG--IILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSL 101
           E K +G +QI+ G+  ++LG  +++ +  ++P    V        YP  G   +IISGSL
Sbjct: 48  ESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVW-------YPLWGGIMYIISGSL 100

Query: 102 SIATEKRLTKLLVHSSLVGSILSALSALVGFII 134
             ATEK   K LV   ++ + LS  +A+ G I+
Sbjct: 101 LAATEKNSRKCLVKGKMIMNSLSLFAAISGMIL 133


>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 31/93 (33%), Positives = 50/93 (53%), Gaps = 9/93 (9%)

Query: 44  EIKVIGTIQILCGMMVLSLG--IILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSL 101
           E K +G +QI+ G+  ++LG  +++ +  ++P    V        YP  G   +IISGSL
Sbjct: 48  ESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVW-------YPLWGGIMYIISGSL 100

Query: 102 SIATEKRLTKLLVHSSLVGSILSALSALVGFII 134
             ATEK   K LV   ++ + LS  +A+ G I+
Sbjct: 101 LAATEKNSRKCLVKGKMIMNSLSLFAAISGMIL 133


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 34/105 (32%), Positives = 56/105 (53%), Gaps = 6/105 (5%)

Query: 36  SLKKHLHAEIKVIGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFF 95
           SL   L  E +V+G  QIL  ++++  G I A       F+Q    ++ + YPF G   F
Sbjct: 33  SLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIG--FSQRLPLVVLTGYPFWGALIF 90

Query: 96  IISGSLSIATEKRLTKLLVHSSLVGSILSALSALVG--FIILSVK 138
           I++G L++  +K  +KLL       +++S+L A+ G  F ILS +
Sbjct: 91  ILTGYLTVTDKK--SKLLGQGVTGMNVISSLVAITGITFTILSYR 133


>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
           isoform 2 [Homo sapiens]
          Length = 147

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 27/53 (50%), Positives = 32/53 (60%)

Query: 83  LNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
           +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS ++A  G  IL
Sbjct: 12  IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64


>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 48  IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
           +GT  +   + +L +G+    ++ +P           S YP  G   +I+SGSLS+   K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201

Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
             +  +V+SS+  +I+SAL A  G  I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229


>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 48  IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
           +GT  +   + +L +G+    ++ +P           S YP  G   +I+SGSLS+   K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201

Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
             +  +V+SS+  +I+SAL A  G  I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229


>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 48  IGTIQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEK 107
           +GT  +   + +L +G+    ++ +P           S YP  G   +I+SGSLS+   K
Sbjct: 143 VGTASLQTAIQIL-IGLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAK 201

Query: 108 RLTKLLVHSSLVGSILSALSALVGFIIL 135
             +  +V+SS+  +I+SAL A  G  I+
Sbjct: 202 DPSPCVVNSSISFNIISALFAFAGIFII 229


>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
           [Homo sapiens]
          Length = 267

 Score = 35.8 bits (81), Expect = 0.020
 Identities = 33/121 (27%), Positives = 51/121 (42%), Gaps = 13/121 (10%)

Query: 23  QAEKPEPTNQGQDSLKKHLHAE-------IKVIGTIQILCGMMVLSLGIILASASFSPNF 75
           Q   P+ T Q +  L  H H +       +K +G   I   ++ L  G  LAS       
Sbjct: 29  QTSAPQNTTQPK-LLAPHQHEKSQKKSSLLKELGAFHITIALLHLVFGGYLASI-----V 82

Query: 76  TQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135
             +   +L S YPF G   F+ISG L+I  +      L    L+ +++S    L G  ++
Sbjct: 83  KNLHLVVLKSWYPFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVI 142

Query: 136 S 136
           S
Sbjct: 143 S 143


>gi|46249347 membrane-spanning 4-domains, subfamily A, member 7
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 33.5 bits (75), Expect = 0.099
 Identities = 22/60 (36%), Positives = 32/60 (53%)

Query: 95  FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQWNSLSD 154
           F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+     L  AS    S  D
Sbjct: 50  FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMD 109


>gi|46249359 membrane-spanning 4-domains, subfamily A, member 7
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 33.5 bits (75), Expect = 0.099
 Identities = 22/60 (36%), Positives = 32/60 (53%)

Query: 95  FIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQWNSLSD 154
           F I+GSLSI + K+ TK    SSL  + +S+++A  G  +L+     L  AS    S  D
Sbjct: 50  FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQHCGSEMD 109


>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
          Length = 539

 Score = 33.1 bits (74), Expect = 0.13
 Identities = 30/119 (25%), Positives = 52/119 (43%), Gaps = 8/119 (6%)

Query: 51  IQILCGMMVLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLT 110
           I +  G   ++LG ++ + SF+      TS  +  + PF   F  ++SG + + + KR  
Sbjct: 31  IVLALGATQMALGCLIVAVSFAA-LALTTSARVRHSCPFWAGFSVLLSGLIGVVSWKRPL 89

Query: 111 KLLVHSSLVGSILSALSALVGFIILSVKQATLNPASLQWNSLSDADLHSAGILPSCAHC 169
            L++   ++ S +  +  L G  ILS + A L       NSL    L     +  C  C
Sbjct: 90  SLVITFFMLLSAVCVMLNLAG-SILSCQNAQL------VNSLEGCQLIKFDSVEVCVCC 141


>gi|24308237 phosphatidylinositol transfer protein,
           membrane-associated 2 [Homo sapiens]
          Length = 1349

 Score = 31.6 bits (70), Expect = 0.38
 Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 14/105 (13%)

Query: 69  ASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLT---KLLVHSSLVGSILSA 125
           A+ SP + +  +T++  A    G F         I +++ +T   ++ +    VG IL+ 
Sbjct: 518 ATSSPQYQEAVATVIQRANLAYGDF---------IKSQEGMTFNGQVCLIGDCVGGILAF 568

Query: 126 LSALVGFIILSVKQATLNPASLQWNSLSDADLHSAGILPSCAHCC 170
            +       +S  Q++    S+   S+ D DL S GIL + AHCC
Sbjct: 569 DALCYSNQPVSESQSSSRRGSVV--SMQDNDLLSPGILMNAAHCC 611


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,088,551
Number of Sequences: 37866
Number of extensions: 223233
Number of successful extensions: 616
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 567
Number of HSP's gapped (non-prelim): 43
length of query: 178
length of database: 18,247,518
effective HSP length: 96
effective length of query: 82
effective length of database: 14,612,382
effective search space: 1198215324
effective search space used: 1198215324
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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