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Search of human proteins with 23110997
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
(200 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [... 400 e-112
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A... 82 2e-16
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A... 82 2e-16
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A... 82 2e-16
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i... 82 4e-16
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i... 82 4e-16
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i... 69 2e-12
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ... 69 3e-12
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ... 69 3e-12
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ... 69 3e-12
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [... 67 8e-12
gi|149588599 membrane-spanning 4-domains, subfamily A, member 15... 67 1e-11
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 65 3e-11
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [... 61 7e-10
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [... 61 7e-10
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i... 59 3e-09
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i... 59 3e-09
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ... 57 1e-08
gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 53 2e-07
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ... 51 6e-07
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ... 51 6e-07
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ... 51 6e-07
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is... 48 6e-06
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ... 47 8e-06
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10... 47 8e-06
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ... 44 9e-05
gi|155029533 membrane-spanning 4-domains, subfamily A, member 13... 38 0.007
gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 i... 32 0.28
gi|239753676 PREDICTED: hypothetical protein [Homo sapiens] 32 0.47
gi|239748302 PREDICTED: hypothetical protein [Homo sapiens] 32 0.47
>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
[Homo sapiens]
Length = 200
Score = 400 bits (1027), Expect = e-112
Identities = 200/200 (100%), Positives = 200/200 (100%)
Query: 1 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60
MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM
Sbjct: 1 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60
Query: 61 TFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIM 120
TFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIM
Sbjct: 61 TFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIM 120
Query: 121 NFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI 180
NFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI
Sbjct: 121 NFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI 180
Query: 181 SLPFSILGCHSEDCDCEQCC 200
SLPFSILGCHSEDCDCEQCC
Sbjct: 181 SLPFSILGCHSEDCDCEQCC 200
>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 1 [Homo sapiens]
Length = 243
Score = 82.4 bits (202), Expect = 2e-16
Identities = 45/152 (29%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
Query: 40 QKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSG 99
+K F RK K+LG ++IL +M+ S G+I + Y P Y WGSV+FI S
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISV 119
Query: 100 AFLIAVKRKTTETLIILSRIMNFLSALGAIAGIIL--LTFGFILDQNYICGYSHQNSQCK 157
+ +A +TT+ L+ S N S++ AI+GI++ ++ F + + C + +S C
Sbjct: 120 SLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCY 179
Query: 158 AVTVLFLGILITLMTFSIIELFISLPFSILGC 189
+ +G ++ S++E I++ S GC
Sbjct: 180 MTMSILMGTDGMVLLLSVLEFCIAVSLSAFGC 211
>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 82.4 bits (202), Expect = 2e-16
Identities = 45/152 (29%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
Query: 40 QKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSG 99
+K F RK K+LG ++IL +M+ S G+I + Y P Y WGSV+FI S
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISV 119
Query: 100 AFLIAVKRKTTETLIILSRIMNFLSALGAIAGIIL--LTFGFILDQNYICGYSHQNSQCK 157
+ +A +TT+ L+ S N S++ AI+GI++ ++ F + + C + +S C
Sbjct: 120 SLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCY 179
Query: 158 AVTVLFLGILITLMTFSIIELFISLPFSILGC 189
+ +G ++ S++E I++ S GC
Sbjct: 180 MTMSILMGTDGMVLLLSVLEFCIAVSLSAFGC 211
>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
member 4E isoform 3 [Homo sapiens]
Length = 243
Score = 82.4 bits (202), Expect = 2e-16
Identities = 45/152 (29%), Positives = 78/152 (51%), Gaps = 2/152 (1%)
Query: 40 QKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSG 99
+K F RK K+LG ++IL +M+ S G+I + Y P Y WGSV+FI S
Sbjct: 60 EKFFKRKPKVLGVVRILIALMSLSMGIIMMCVAFSSYEEHPIFVYVAYTIWGSVMFIISV 119
Query: 100 AFLIAVKRKTTETLIILSRIMNFLSALGAIAGIIL--LTFGFILDQNYICGYSHQNSQCK 157
+ +A +TT+ L+ S N S++ AI+GI++ ++ F + + C + +S C
Sbjct: 120 SLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTFYSFRYHYCNHDQLSSNCY 179
Query: 158 AVTVLFLGILITLMTFSIIELFISLPFSILGC 189
+ +G ++ S++E I++ S GC
Sbjct: 180 MTMSILMGTDGMVLLLSVLEFCIAVALSAFGC 211
>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
isoform a [Homo sapiens]
Length = 220
Score = 81.6 bits (200), Expect = 4e-16
Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 2/152 (1%)
Query: 40 QKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSG 99
+K + K+LG +QIL +M+ S G+ + Y P GY WGSV+FI SG
Sbjct: 37 EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISG 96
Query: 100 AFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTF--GFILDQNYICGYSHQNSQCK 157
+ IA +TT+ L+ S MN S++ A +GI++ TF F + C Y ++ C
Sbjct: 97 SLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCH 156
Query: 158 AVTVLFLGILITLMTFSIIELFISLPFSILGC 189
+ +G+ ++ S++E I++ S GC
Sbjct: 157 GTMSILMGLDGMVLLLSVLEFCIAVSLSAFGC 188
>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
isoform b [Homo sapiens]
Length = 239
Score = 81.6 bits (200), Expect = 4e-16
Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 2/152 (1%)
Query: 40 QKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSG 99
+K + K+LG +QIL +M+ S G+ + Y P GY WGSV+FI SG
Sbjct: 56 EKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISG 115
Query: 100 AFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTF--GFILDQNYICGYSHQNSQCK 157
+ IA +TT+ L+ S MN S++ A +GI++ TF F + C Y ++ C
Sbjct: 116 SLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCH 175
Query: 158 AVTVLFLGILITLMTFSIIELFISLPFSILGC 189
+ +G+ ++ S++E I++ S GC
Sbjct: 176 GTMSILMGLDGMVLLLSVLEFCIAVSLSAFGC 207
>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
isoform a [Homo sapiens]
Length = 214
Score = 69.3 bits (168), Expect = 2e-12
Identities = 59/206 (28%), Positives = 98/206 (47%), Gaps = 19/206 (9%)
Query: 1 MDSSTAH-SPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGI 59
+ S++AH +P P E+ S Y+ + S QK K+++LG IQIL
Sbjct: 11 LGSASAHGTPGSEAGPEELNTSVYQPIDGSPD-------YQKA---KLQVLGAIQILNAA 60
Query: 60 MTFSFGVIFLFTLLKPYPR----FPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLII 115
M + GV FL +L PY F F F +GYP WG+V F +SG + K T T I
Sbjct: 61 MILALGV-FLGSLQYPYHFQKHFFFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQ 119
Query: 116 LSRIMNFLSALGAIAGIILLTFGFILDQNYI--CGYSHQNSQ-CKAVTVLFLGILITLMT 172
S MN SA A+ G L+ ++ + C S ++ C + + G++ L+
Sbjct: 120 NSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSESPDLCNYMGSISNGMVSLLLI 179
Query: 173 FSIIELFISLPFSILGCHSEDCDCEQ 198
+++EL +++ + C++ C+ +
Sbjct: 180 LTLLELCVTISTIAMWCNANCCNSRE 205
>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
isoform 2 [Homo sapiens]
Length = 225
Score = 68.6 bits (166), Expect = 3e-12
Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 4/138 (2%)
Query: 1 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60
M S + +V P + + E T Q L+K ++K++GTIQIL G+M
Sbjct: 1 MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM 58
Query: 61 TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR 118
S G+I P + + L S YPF G FI SG+ IA +++ T+ L+ S
Sbjct: 59 VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL 118
Query: 119 IMNFLSALGAIAGIILLT 136
+ + LSAL A+ G I+L+
Sbjct: 119 VGSILSALSALVGFIILS 136
>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
isoform 3 [Homo sapiens]
Length = 178
Score = 68.6 bits (166), Expect = 3e-12
Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 4/138 (2%)
Query: 1 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60
M S + +V P + + E T Q L+K ++K++GTIQIL G+M
Sbjct: 1 MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM 58
Query: 61 TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR 118
S G+I P + + L S YPF G FI SG+ IA +++ T+ L+ S
Sbjct: 59 VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL 118
Query: 119 IMNFLSALGAIAGIILLT 136
+ + LSAL A+ G I+L+
Sbjct: 119 VGSILSALSALVGFIILS 136
>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
isoform 1 [Homo sapiens]
Length = 248
Score = 68.6 bits (166), Expect = 3e-12
Identities = 45/138 (32%), Positives = 69/138 (50%), Gaps = 4/138 (2%)
Query: 1 MDSSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIM 60
M S + +V P + + E T Q L+K ++K++GTIQIL G+M
Sbjct: 1 MTSQPVPNETIIVLPSNVI--NFSQAEKPEPTNQGQDSLKKHLHAEIKVIGTIQILCGMM 58
Query: 61 TFSFGVIFLFTLLKP-YPRFPFIFL-SGYPFWGSVLFINSGAFLIAVKRKTTETLIILSR 118
S G+I P + + L S YPF G FI SG+ IA +++ T+ L+ S
Sbjct: 59 VLSLGIILASASFSPNFTQVTSTLLNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSL 118
Query: 119 IMNFLSALGAIAGIILLT 136
+ + LSAL A+ G I+L+
Sbjct: 119 VGSILSALSALVGFIILS 136
>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
[Homo sapiens]
Length = 267
Score = 67.4 bits (163), Expect = 8e-12
Identities = 43/142 (30%), Positives = 71/142 (50%), Gaps = 11/142 (7%)
Query: 43 FARKMKILGTIQILFGIMTFSFGVIFL---FTLLKPYPRFPFIFLSGYPFWGSVLFINSG 99
F + K LG IQI+ G+M FG++ F+ + + GYPFWG + FI SG
Sbjct: 84 FKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISG 143
Query: 100 AFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAV 159
+ ++ ++ + L+ S MN +S++ A G+ILL + N + G +
Sbjct: 144 SLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCI--NGVAGQDYW------A 195
Query: 160 TVLFLGILITLMTFSIIELFIS 181
+ GI TLM FS++E F++
Sbjct: 196 VLSGKGISATLMIFSLLEFFVA 217
>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
isoform 1 [Homo sapiens]
Length = 240
Score = 66.6 bits (161), Expect = 1e-11
Identities = 55/190 (28%), Positives = 88/190 (46%), Gaps = 29/190 (15%)
Query: 9 PVFLVFPPEITASEYESTELSATT-FSTQSP----LQKLFARKMKILGTIQILFGIMTFS 63
P + PP I ++E L A T +TQ P ++ + K+LGT+QIL G++
Sbjct: 30 PTSMCQPPGIM--QFEEPPLGAQTPRATQPPDLRPVETFLTGEPKVLGTVQILIGLIHLG 87
Query: 64 FGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFL 123
FG + L +++ F G PFWG FI SG+ +A ++ T L+ S N L
Sbjct: 88 FGSVLL--MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNIL 145
Query: 124 SALGAIAG--IILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFIS 181
S + A AG I+L+ FG + +++ GY L L F+++E F +
Sbjct: 146 SVMAAFAGTAILLMDFG-VTNRDVDRGY-----------------LAVLTIFTVLEFFTA 187
Query: 182 LPFSILGCHS 191
+ GC +
Sbjct: 188 VIAMHFGCQA 197
>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
isoform 1 [Homo sapiens]
Length = 679
Score = 65.5 bits (158), Expect = 3e-11
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 14/155 (9%)
Query: 26 TELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLS 85
T L+A + S L + ++LG QIL ++ FG IF + R P + L+
Sbjct: 21 TVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLT 80
Query: 86 GYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNY 145
GYPFWG+++FI +G + V K ++ L MN +S+L AI GI TF
Sbjct: 81 GYPFWGALIFILTG--YLTVTDKKSKLLGQGVTGMNVISSLVAITGI---TF-------T 128
Query: 146 ICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI 180
I Y HQ+ C+ + F I + T I+ F+
Sbjct: 129 ILSYRHQDKYCQMPS--FEEICVFSRTLFIVLFFL 161
>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 60.8 bits (146), Expect = 7e-10
Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 33/173 (19%)
Query: 34 STQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRF-PFIFLSGYPFWGS 92
S P Q F R+ K LG +QI+ G+ + G + L+ P + P YP WG
Sbjct: 36 SLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGL----LMIPAGIYAPICVTVWYPLWGG 91
Query: 93 VLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFI----------LD 142
+++I SG+ L A ++ + + L+ IMN LS AI+G+IL +
Sbjct: 92 IMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMES 151
Query: 143 QNYICGY--------------SHQNS----QCKAVTVLFLGILITLMTFSIIE 177
N+I + S +NS C ++ LFLGIL ++ F+ +
Sbjct: 152 LNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQ 204
>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
[Homo sapiens]
Length = 297
Score = 60.8 bits (146), Expect = 7e-10
Identities = 48/173 (27%), Positives = 77/173 (44%), Gaps = 33/173 (19%)
Query: 34 STQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRF-PFIFLSGYPFWGS 92
S P Q F R+ K LG +QI+ G+ + G + L+ P + P YP WG
Sbjct: 36 SLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGL----LMIPAGIYAPICVTVWYPLWGG 91
Query: 93 VLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFI----------LD 142
+++I SG+ L A ++ + + L+ IMN LS AI+G+IL +
Sbjct: 92 IMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMES 151
Query: 143 QNYICGY--------------SHQNS----QCKAVTVLFLGILITLMTFSIIE 177
N+I + S +NS C ++ LFLGIL ++ F+ +
Sbjct: 152 LNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQ 204
>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 58.9 bits (141), Expect = 3e-09
Identities = 46/177 (25%), Positives = 85/177 (48%), Gaps = 26/177 (14%)
Query: 33 FSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRF--PFI---FLSGY 87
+ + LQ + +LGT+QIL ++ S G I +F PYP P I +SGY
Sbjct: 31 YQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFA---PYPSHFNPAISTTLMSGY 87
Query: 88 PFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFIL------ 141
PF G++ F +G+ I +++T+ + S N +S++ A AG+ LL +
Sbjct: 88 PFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQ 147
Query: 142 ----DQNYICG--YS------HQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSI 186
+ +Y+ YS ++ C +V G+L+ ++ F+++EL ++ S+
Sbjct: 148 HCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSV 204
>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
isoform 1 [Homo sapiens]
Length = 240
Score = 58.9 bits (141), Expect = 3e-09
Identities = 46/177 (25%), Positives = 85/177 (48%), Gaps = 26/177 (14%)
Query: 33 FSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRF--PFI---FLSGY 87
+ + LQ + +LGT+QIL ++ S G I +F PYP P I +SGY
Sbjct: 31 YQNEDYLQNGLPTETTVLGTVQILCCLLISSLGAILVFA---PYPSHFNPAISTTLMSGY 87
Query: 88 PFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFIL------ 141
PF G++ F +G+ I +++T+ + S N +S++ A AG+ LL +
Sbjct: 88 PFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLLADSMVALRTASQ 147
Query: 142 ----DQNYICG--YS------HQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSI 186
+ +Y+ YS ++ C +V G+L+ ++ F+++EL ++ S+
Sbjct: 148 HCGSEMDYLSSLPYSEYYYPIYEIKDCLLTSVSLTGVLVVMLIFTVLELLLAAYSSV 204
>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
[Homo sapiens]
Length = 250
Score = 57.0 bits (136), Expect = 1e-08
Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 9/159 (5%)
Query: 38 PLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFIN 97
P+QK ++ K LG IQI+ G+ G I L+ Y F G+PFWG + FI
Sbjct: 61 PVQKAL-KEGKTLGAIQIIIGLAHIGLGSIMATVLVGEY--LSISFYGGFPFWGGLWFII 117
Query: 98 SGAFLIAVKRKTTETLIILSRI-MNFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQC 156
SG+ +A + + ++ + +N +SA+ + G+IL FI D + Y++ +
Sbjct: 118 SGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVIL----FITDLSIPHPYAYPDYYP 173
Query: 157 KAVTV-LFLGILITLMTFSIIELFISLPFSILGCHSEDC 194
A V + I L+ F ++E I+ S GC C
Sbjct: 174 YAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCC 212
>gi|119226220 membrane-spanning 4-domains, subfamily A, member 14
isoform 2 [Homo sapiens]
Length = 662
Score = 53.1 bits (126), Expect = 2e-07
Identities = 45/155 (29%), Positives = 65/155 (41%), Gaps = 31/155 (20%)
Query: 26 TELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLS 85
T L+A + S L + ++LG QIL ++ FG IF + R P + L+
Sbjct: 21 TVLTAFPYRPHSSLLDFLKGEPRVLGATQILLALIIVGFGTIFALNYIGFSQRLPLVVLT 80
Query: 86 GYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNY 145
GYPFWG++ I G MN +S+L AI GI TF
Sbjct: 81 GYPFWGAL--IGQGV-----------------TGMNVISSLVAITGI---TF-------T 111
Query: 146 ICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFI 180
I Y HQ+ C+ + F I + T I+ F+
Sbjct: 112 ILSYRHQDKYCQMPS--FEEICVFSRTLFIVLFFL 144
>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 51.2 bits (121), Expect = 6e-07
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 17/132 (12%)
Query: 65 GVIFLFTLLKPYPRF-PFI-FLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNF 122
G+ +F+ + P + PF+ +LSGYP WG + +I SG+ + + + ++ S N
Sbjct: 157 GLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNI 216
Query: 123 LSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISL 182
+SAL A AGI ++ L Y+ YS KAV+ L+ F+++E ++
Sbjct: 217 ISALFAFAGIFIIITD--LSLYYVTTYS------KAVSG-------GLLPFALLEFILTC 261
Query: 183 PFSILGCHSEDC 194
S GC + C
Sbjct: 262 VVSHFGCQATCC 273
>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 51.2 bits (121), Expect = 6e-07
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 17/132 (12%)
Query: 65 GVIFLFTLLKPYPRF-PFI-FLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNF 122
G+ +F+ + P + PF+ +LSGYP WG + +I SG+ + + + ++ S N
Sbjct: 157 GLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNI 216
Query: 123 LSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISL 182
+SAL A AGI ++ L Y+ YS KAV+ L+ F+++E ++
Sbjct: 217 ISALFAFAGIFIIITD--LSLYYVTTYS------KAVSG-------GLLPFALLEFILTC 261
Query: 183 PFSILGCHSEDC 194
S GC + C
Sbjct: 262 VVSHFGCQATCC 273
>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
subfamily A, member 8B [Homo sapiens]
Length = 391
Score = 51.2 bits (121), Expect = 6e-07
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 17/132 (12%)
Query: 65 GVIFLFTLLKPYPRF-PFI-FLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNF 122
G+ +F+ + P + PF+ +LSGYP WG + +I SG+ + + + ++ S N
Sbjct: 157 GLTHIFSAINPVLYYYPFVTWLSGYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNI 216
Query: 123 LSALGAIAGIILLTFGFILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISL 182
+SAL A AGI ++ L Y+ YS KAV+ L+ F+++E ++
Sbjct: 217 ISALFAFAGIFIIITD--LSLYYVTTYS------KAVSG-------GLLPFALLEFILTC 261
Query: 183 PFSILGCHSEDC 194
S GC + C
Sbjct: 262 VVSHFGCQATCC 273
>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
isoform 1 [Homo sapiens]
Length = 244
Score = 47.8 bits (112), Expect = 6e-06
Identities = 48/194 (24%), Positives = 81/194 (41%), Gaps = 8/194 (4%)
Query: 3 SSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTF 62
SS V + P E+++ + S + + L+K + + LG QIL ++
Sbjct: 18 SSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKK----EQEFLGVTQILTAMICL 73
Query: 63 SFGVIFLFTLLKPYPRFPFI--FLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIM 120
FG + L + F +GYPFWG++ F SG I +R+ L+ S
Sbjct: 74 CFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGA 133
Query: 121 NFLSALGAIAGIILLTFGFILDQNYICGYSHQN-SQCKAVTVLFLGILITLMTF-SIIEL 178
N S++ GI +L YI +S Q + K F ++ +M F +I+ L
Sbjct: 134 NTASSIAGGTGITILIINLKKSLAYIHIHSCQKFFETKCFMASFSTEIVVMMLFLTILGL 193
Query: 179 FISLPFSILGCHSE 192
++ +I G E
Sbjct: 194 GSAVSLTICGAGEE 207
>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
isoform 2 [Homo sapiens]
Length = 147
Score = 47.4 bits (111), Expect = 8e-06
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 20/113 (17%)
Query: 81 FIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAG--IILLTFG 138
F G PFWG FI SG+ +A ++ T L+ S N LS + A AG I+L+ FG
Sbjct: 10 FFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFG 69
Query: 139 FILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSILGCHS 191
+ +++ GY L L F+++E F ++ GC +
Sbjct: 70 -VTNRDVDRGY-----------------LAVLTIFTVLEFFTAVIAMHFGCQA 104
>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
[Homo sapiens]
Length = 267
Score = 47.4 bits (111), Expect = 8e-06
Identities = 35/142 (24%), Positives = 69/142 (48%), Gaps = 10/142 (7%)
Query: 47 MKILGTIQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVK 106
+K LG I ++ FG +L +++K + S YPFWG+ F+ SG I +K
Sbjct: 57 LKELGAFHITIALLHLVFGG-YLASIVKNLHLV--VLKSWYPFWGAASFLISGILAITMK 113
Query: 107 RKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGY--SHQNSQCKAVTVLFL 164
+ L +L + N +S ++G+ +++ L+ + + NS TV
Sbjct: 114 TFSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFESPIWRMYPNS-----TVHIQ 168
Query: 165 GILITLMTFSIIELFISLPFSI 186
+ + L+ F+++ELF+ +P ++
Sbjct: 169 RLELALLCFTVLELFLPVPTAV 190
>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
isoform 2 [Homo sapiens]
Length = 195
Score = 43.9 bits (102), Expect = 9e-05
Identities = 39/152 (25%), Positives = 63/152 (41%), Gaps = 6/152 (3%)
Query: 3 SSTAHSPVFLVFPPEITASEYESTELSATTFSTQSPLQKLFARKMKILGTIQILFGIMTF 62
SS V + P E+++ + S + + L+K + + LG QIL ++
Sbjct: 18 SSVPAFEVLEISPQEVSSGRLLKSASSPPLHTWLTVLKK----EQEFLGVTQILTAMICL 73
Query: 63 SFGVIFLFTLLKPYPRFPFI--FLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIM 120
FG + L + F +GYPFWG++ F SG I +R+ L+ S
Sbjct: 74 CFGTVVCSVLDISHIEGDIFSSFKAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGA 133
Query: 121 NFLSALGAIAGIILLTFGFILDQNYICGYSHQ 152
N S++ GI +L YI +S Q
Sbjct: 134 NTASSIAGGTGITILIINLKKSLAYIHIHSCQ 165
>gi|155029533 membrane-spanning 4-domains, subfamily A, member 13
isoform 1 [Homo sapiens]
Length = 152
Score = 37.7 bits (86), Expect = 0.007
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 80 PFIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGF 139
P + +G WG + FI +G FLI V + T + II + I+N + + I + L
Sbjct: 30 PVTYKTGCTLWG-IFFIIAGVFLIRVTKYPTRSGIISTLIINIICIITTITAVTLT---- 84
Query: 140 ILDQNYICGYSHQN-SQCKAVTVLFLGILITLMTFSIIELFISLPFSILGC 189
I++ ++ S++N Q K L + L+ F +E I+L SI C
Sbjct: 85 IIELSHFNSVSYRNYGQAK----LGREVSRILLFFYGLEFSIALTHSIYSC 131
>gi|73486653 membrane-spanning 4-domains, subfamily A, member 3
isoform b [Homo sapiens]
Length = 168
Score = 32.3 bits (72), Expect = 0.28
Identities = 24/107 (22%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Query: 95 FINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAGIILLTFGFILDQNYI--CGYSHQ 152
F +SG + K T T I S MN SA A+ G L+ ++ + C S +
Sbjct: 53 FCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSE 112
Query: 153 NSQ-CKAVTVLFLGILITLMTFSIIELFISLPFSILGCHSEDCDCEQ 198
+ C + + G++ L+ +++EL +++ + C++ C+ +
Sbjct: 113 SPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSRE 159
>gi|239753676 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 31.6 bits (70), Expect = 0.47
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Query: 51 GTIQILFGIMTFSFGVIFLFTLLKPYPRFP-FIFLSGYPFWGSVLFINSGAFLIAVKRKT 109
G I + GI++ GVI F + P F + P W L I +G L+ R+
Sbjct: 9 GRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLAYREW 68
Query: 110 TE--------TLIILSRI---MNFLSAL-GAIAG-IILLTFGFILDQNYICGYS 150
T+ T +ILS + ++F AL A+ G +F I NY+ GY+
Sbjct: 69 TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYL-GYA 121
>gi|239748302 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 31.6 bits (70), Expect = 0.47
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 15/114 (13%)
Query: 51 GTIQILFGIMTFSFGVIFLFTLLKPYPRFP-FIFLSGYPFWGSVLFINSGAFLIAVKRKT 109
G I + GI++ GVI F + P F + P W L I +G L+ R+
Sbjct: 9 GRILVTLGILSVCSGVIAFFPVFSYKPWFTGWSVRIACPIWNGALAITTGVLLLLAYREW 68
Query: 110 TE--------TLIILSRI---MNFLSAL-GAIAG-IILLTFGFILDQNYICGYS 150
T+ T +ILS + ++F AL A+ G +F I NY+ GY+
Sbjct: 69 TQRYLGEATFTFVILSIMGCPLHFAIALESALLGPYCFYSFSGIAGTNYL-GYA 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.144 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,631,053
Number of Sequences: 37866
Number of extensions: 235455
Number of successful extensions: 824
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 775
Number of HSP's gapped (non-prelim): 47
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.