Search of human proteins with 23097338

Search of human proteins with 23097338

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23097338 neurexophilin 1 precursor [Homo sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23097338 neurexophilin 1 precursor [Homo sapiens]                  568   e-162
gi|52138515 neurexophilin 2 [Homo sapiens]                            338   2e-93
gi|217330576 neurexophilin 3 [Homo sapiens]                           255   3e-68
gi|39930315 neurexophilin 4 [Homo sapiens]                            213   1e-55
gi|21450781 hypothetical protein LOC91775 [Homo sapiens]               50   2e-06
gi|197333800 hypothetical protein LOC91775 [Homo sapiens]              50   2e-06
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             37   0.018
gi|56550033 SHQ1 homolog [Homo sapiens]                                36   0.041
gi|117647230 hypothetical protein LOC54827 isoform 1 [Homo sapiens]    33   0.34 
gi|210147446 hypothetical protein LOC120406 [Homo sapiens]             31   1.3  
gi|150456451 hypothetical protein LOC54914 [Homo sapiens]              30   2.2  
gi|169234964 hypothetical protein LOC120400 [Homo sapiens]             29   5.0  
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   28   6.5  
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    28   6.5  
gi|154759275 monocyte to macrophage differentiation-associated 2...    28   6.5  
gi|23510348 TRAF and TNF receptor-associated protein [Homo sapiens]    28   6.5  

>gi|23097338 neurexophilin 1 precursor [Homo sapiens]
          Length = 271

 Score =  568 bits (1464), Expect = e-162
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MQAACWYVLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLS 60
           MQAACWYVLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLS
Sbjct: 1   MQAACWYVLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLS 60

Query: 61  QTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFG 120
           QTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFG
Sbjct: 61  QTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFG 120

Query: 121 WGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQ 180
           WGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQ
Sbjct: 121 WGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQ 180

Query: 181 QTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICI 240
           QTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICI
Sbjct: 181 QTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICI 240

Query: 241 YISFYSTDYKLVQKVCPDYNYHSDTPYFPSG 271
           YISFYSTDYKLVQKVCPDYNYHSDTPYFPSG
Sbjct: 241 YISFYSTDYKLVQKVCPDYNYHSDTPYFPSG 271


>gi|52138515 neurexophilin 2 [Homo sapiens]
          Length = 264

 Score =  338 bits (868), Expect = 2e-93
 Identities = 153/189 (80%), Positives = 170/189 (89%)

Query: 83  SEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIV 142
           S ++ WDWL N T++QEP  R KRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIV
Sbjct: 76  SMENFWDWLANITEIQEPLARTKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIV 135

Query: 143 DHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVD 202
           DHGNGTFSVYFRHNSTG GNVSVSLVPP+K+VEF+++ Q+ ++ K+SKSFNCRIEYEK D
Sbjct: 136 DHGNGTFSVYFRHNSTGLGNVSVSLVPPSKVVEFEVSPQSTLETKESKSFNCRIEYEKTD 195

Query: 203 KATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYH 262
           +A K  LCN+DPSK CYQEQTQSHVSWLCSKPFKVICIYI+FYS DYKLVQKVCPDYNYH
Sbjct: 196 RAKKTALCNFDPSKICYQEQTQSHVSWLCSKPFKVICIYIAFYSVDYKLVQKVCPDYNYH 255

Query: 263 SDTPYFPSG 271
           S+TPY  SG
Sbjct: 256 SETPYLSSG 264


>gi|217330576 neurexophilin 3 [Homo sapiens]
          Length = 252

 Score =  255 bits (652), Expect = 3e-68
 Identities = 114/175 (65%), Positives = 143/175 (81%), Gaps = 1/175 (0%)

Query: 97  LQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHN 156
           L +P  R    P   + K KK+FGWGDF+SNIKTV LNLL+TGKIVDHGNGTFSV+F+HN
Sbjct: 79  LGQPPNRPNHSP-PPSAKVKKIFGWGDFYSNIKTVALNLLVTGKIVDHGNGTFSVHFQHN 137

Query: 157 STGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSK 216
           +TGQGN+S+SLVPP+K VEF   QQ  I+AK SK FNCR+E+EKV++  + +LC +DP+K
Sbjct: 138 ATGQGNISISLVPPSKAVEFHQEQQIFIEAKASKIFNCRMEWEKVERGRRTSLCTHDPAK 197

Query: 217 TCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG 271
            C ++  QS  +W CS+PFKV+C+YI+FYSTDY+LVQKVCPDYNYHSDTPY+PSG
Sbjct: 198 ICSRDHAQSSATWSCSQPFKVVCVYIAFYSTDYRLVQKVCPDYNYHSDTPYYPSG 252


>gi|39930315 neurexophilin 4 [Homo sapiens]
          Length = 308

 Score =  213 bits (542), Expect = 1e-55
 Identities = 114/257 (44%), Positives = 144/257 (56%), Gaps = 67/257 (26%)

Query: 79  PEPYSEQDL-------WDWLRNSTDLQE--------PRPRAKRRPIVKTGKFKKMFGWGD 123
           PEP S   L       W W  N T            P  R KR+P +K  + KK+FGWGD
Sbjct: 51  PEPRSSDGLGVGRAWSWAWPTNHTGALARAGAAGALPAQRTKRKPSIKAARAKKIFGWGD 110

Query: 124 FHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFD------ 177
           F+  + T+K +LL+TGKIVDH NGTFSVYFRHNS+  GN+SVS+VPP+K VEF       
Sbjct: 111 FYFRVHTLKFSLLVTGKIVDHVNGTFSVYFRHNSSSLGNLSVSIVPPSKRVEFGGVWLPG 170

Query: 178 ---------LAQQTVID-------------------------------------AKDSKS 191
                    LA + V+                                      AK+S++
Sbjct: 171 PVPHPLQSTLALEGVLPGLGPPLGMAAAAAGPGLGGSLGGALAGPLGGALGVPGAKESRA 230

Query: 192 FNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKL 251
           FNC +EYEK ++A K+  C YDPS+ C+ E TQS  +WLC+KPFKVICI++SF S DYKL
Sbjct: 231 FNCHVEYEKTNRARKHRPCLYDPSQVCFTEHTQSQAAWLCAKPFKVICIFVSFLSFDYKL 290

Query: 252 VQKVCPDYNYHSDTPYF 268
           VQKVCPDYN+ S+ PYF
Sbjct: 291 VQKVCPDYNFQSEHPYF 307


>gi|21450781 hypothetical protein LOC91775 [Homo sapiens]
          Length = 559

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 2/123 (1%)

Query: 117 KMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEF 176
           K +G     + I ++KL     G++VD+ NG + V+F     G+  VSVSLV P++ +  
Sbjct: 137 KKYGGDYLQARIHSLKLQAGAVGRVVDYQNGFYKVFFTLLWPGKVKVSVSLVHPSEGIR- 195

Query: 177 DLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFK 236
            + Q+   D  D   F       ++ + T+  +C       C      +   W C KP K
Sbjct: 196 -VLQRLQEDKPDRVYFKSLFRSGRISETTECNVCLPGNLPLCNFTDLYTGEPWFCFKPKK 254

Query: 237 VIC 239
           + C
Sbjct: 255 LPC 257


>gi|197333800 hypothetical protein LOC91775 [Homo sapiens]
          Length = 559

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 2/123 (1%)

Query: 117 KMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEF 176
           K +G     + I ++KL     G++VD+ NG + V+F     G+  VSVSLV P++ +  
Sbjct: 137 KKYGGDYLQARIHSLKLQAGAVGRVVDYQNGFYKVFFTLLWPGKVKVSVSLVHPSEGIR- 195

Query: 177 DLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFK 236
            + Q+   D  D   F       ++ + T+  +C       C      +   W C KP K
Sbjct: 196 -VLQRLQEDKPDRVYFKSLFRSGRISETTECNVCLPGNLPLCNFTDLYTGEPWFCFKPKK 254

Query: 237 VIC 239
           + C
Sbjct: 255 LPC 257


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 37.0 bits (84), Expect = 0.018
 Identities = 18/53 (33%), Positives = 29/53 (54%)

Query: 163  VSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPS 215
            +++S  P T  +   L  Q+  DA+ +K   CR+E+  + K T NT   YDP+
Sbjct: 1128 INISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPN 1180


>gi|56550033 SHQ1 homolog [Homo sapiens]
          Length = 577

 Score = 35.8 bits (81), Expect = 0.041
 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 22/131 (16%)

Query: 104 AKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGN---------GTFSVYFR 154
           A R P  +  +F   F   DF    K   L L + G+IV++G+         G F++   
Sbjct: 18  AIRVPYARVSEFDVYFEGSDFKFYAKPYFLRLTLPGRIVENGSEQGSYDADKGIFTIRLP 77

Query: 155 HNSTGQG----NVSVSLVPPTK------IVEFDLAQQTVIDAKDSKSFNCRIEY---EKV 201
             + GQ     N+  +L+ P K      +VE   A +   +  D + F+  IE    E+V
Sbjct: 78  KETPGQHFEGLNMLTALLAPRKSRTAKPLVEEIGASEIPEEVVDDEEFDWEIEQTPCEEV 137

Query: 202 DKATKNTLCNY 212
            ++  N  C+Y
Sbjct: 138 SESALNPQCHY 148


>gi|117647230 hypothetical protein LOC54827 isoform 1 [Homo sapiens]
          Length = 544

 Score = 32.7 bits (73), Expect = 0.34
 Identities = 43/180 (23%), Positives = 73/180 (40%), Gaps = 22/180 (12%)

Query: 8   VLFLLQPTVYLVTCANLTNGGKSELLKSGSSKSTLKHIWTESSKDL-------SISRLLS 60
           +LF+L   +      N T       + S  + S   H W  S+K L       S+  L  
Sbjct: 14  LLFILASWIIFTVFQNSTK------VWSALNLSISLHYWNNSTKSLFPKTPLISLKPLTE 67

Query: 61  QTFRGKENDTDLDLRYDTPEPYSEQDLWDWLRNST-DLQEPRP---RAKRRPIVKTGKF- 115
              R KE    LD +   P P++  +      +ST  +  PR    R  +  I+   +  
Sbjct: 68  TELRIKEIIEKLDQQIP-PRPFTHVNTTTSATHSTATILNPRDTYCRGDQLHILLEVRDH 126

Query: 116 ---KKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTK 172
              +K +G     + + +  L    +GK+ D  NGT+ V F     GQ ++S+ L+ P++
Sbjct: 127 LGRRKQYGGDFLRARMSSPALMAGASGKVTDFNNGTYLVSFTLFWEGQVSLSLLLIHPSE 186


>gi|210147446 hypothetical protein LOC120406 [Homo sapiens]
          Length = 559

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 16/57 (28%), Positives = 30/57 (52%)

Query: 116 KKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTK 172
           +K +G     + + +  L    +GK+ D  NGT+ V F     GQ ++S+ L+ P++
Sbjct: 142 RKQYGGDFLRARMYSTALMAGASGKVTDFNNGTYLVSFTLFWEGQVSLSLLLIHPSE 198


>gi|150456451 hypothetical protein LOC54914 [Homo sapiens]
          Length = 1801

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 15/61 (24%), Positives = 29/61 (47%), Gaps = 4/61 (6%)

Query: 55  ISRLLSQTFRGKENDTDLDLRYDTPEP----YSEQDLWDWLRNSTDLQEPRPRAKRRPIV 110
           ++R      +G+  + +L L++   EP    Y +   W W+R+    +  +  AK  P+V
Sbjct: 897 MNRAYHAILQGRLGELELQLKHGKEEPEEVQYKKSTAWLWVRDMLTDEITKAAAKESPVV 956

Query: 111 K 111
           K
Sbjct: 957 K 957


>gi|169234964 hypothetical protein LOC120400 [Homo sapiens]
          Length = 405

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 13/35 (37%), Positives = 23/35 (65%)

Query: 138 TGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTK 172
           +GK++D  NGT+ V F     GQ ++S+ L+ P++
Sbjct: 11  SGKVMDFNNGTYLVSFTLFWEGQVSLSLLLIHPSE 45


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 26  NGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEP 81
           N   S    S SS ST++ I  +SSK+ + +R L +  + K+N  +   +  TP+P
Sbjct: 122 NQESSSSSSSSSSSSTIRKI--KSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 175


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 2/56 (3%)

Query: 26  NGGKSELLKSGSSKSTLKHIWTESSKDLSISRLLSQTFRGKENDTDLDLRYDTPEP 81
           N   S    S SS ST++ I  +SSK+ + +R L +  + K+N  +   +  TP+P
Sbjct: 163 NQESSSSSSSSSSSSTIRKI--KSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP 216


>gi|154759275 monocyte to macrophage differentiation-associated 2
           isoform 2 [Homo sapiens]
          Length = 246

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 225 SHVSWLCSKPFKVICIYISFYSTDYKLVQKVC 256
           SH+ WL      V  IY+ F+   YKLV+ +C
Sbjct: 133 SHMRWLVWIMASVGTIYVFFFHERYKLVELLC 164


>gi|23510348 TRAF and TNF receptor-associated protein [Homo sapiens]
          Length = 362

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 10/68 (14%)

Query: 202 DKATKNTLCNYDPSKTCYQEQTQ--SHVSWLC--------SKPFKVICIYISFYSTDYKL 251
           ++ T +T     PS+   QE     S ++W          S+  + +C Y++ YS D   
Sbjct: 90  EETTDSTTSKISPSEDTQQENGSMFSLITWNIDGLDLNNLSERARGVCSYLALYSPDVIF 149

Query: 252 VQKVCPDY 259
           +Q+V P Y
Sbjct: 150 LQEVIPPY 157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,046,752
Number of Sequences: 37866
Number of extensions: 487080
Number of successful extensions: 1084
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1070
Number of HSP's gapped (non-prelim): 19
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.