Search of human proteins with 229892328

Search of human proteins with 229892328

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]
         (546 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]          1138   0.0  
gi|229892326 IQ motif containing C isoform 2 [Homo sapiens]           948   0.0  
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            41   0.002
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap...    39   0.009
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    37   0.036
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    37   0.061
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    37   0.061
gi|56549694 enabled homolog isoform a [Homo sapiens]                   35   0.14 
gi|39930375 enabled homolog isoform b [Homo sapiens]                   35   0.14 
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    35   0.14 
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    35   0.14 
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         35   0.18 
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    35   0.23 
gi|148746195 trichohyalin [Homo sapiens]                               35   0.23 
gi|44890059 involucrin [Homo sapiens]                                  34   0.30 
gi|33354279 hypothetical protein LOC55425 [Homo sapiens]               34   0.30 
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]           34   0.39 
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          33   0.51 
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            33   0.51 
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]                  33   0.51 
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]                  33   0.51 
gi|148727255 microtubule associated serine/threonine kinase fami...    33   0.51 
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso...    33   0.51 
gi|224458301 family with sequence similarity 186, member A [Homo...    33   0.67 
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    33   0.67 
gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]              33   0.67 
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         33   0.88 
gi|221139761 zinc finger protein 853 [Homo sapiens]                    32   1.1  
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]                    32   1.1  
gi|110349719 titin isoform N2-A [Homo sapiens]                         32   1.5  

>gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]
          Length = 546

 Score = 1138 bits (2943), Expect = 0.0
 Identities = 546/546 (100%), Positives = 546/546 (100%)

Query: 1   MEPELLVRKVSALQVRGRARGSQDFSFREIMGSRTWTSQRDATTFSPLTARQPLEIPAVP 60
           MEPELLVRKVSALQVRGRARGSQDFSFREIMGSRTWTSQRDATTFSPLTARQPLEIPAVP
Sbjct: 1   MEPELLVRKVSALQVRGRARGSQDFSFREIMGSRTWTSQRDATTFSPLTARQPLEIPAVP 60

Query: 61  NRAEESWDPRTPCPARPHSHHTLAPDQGNGKSLKACVRGFLVRRQFQSLRAEYEAIVREV 120
           NRAEESWDPRTPCPARPHSHHTLAPDQGNGKSLKACVRGFLVRRQFQSLRAEYEAIVREV
Sbjct: 61  NRAEESWDPRTPCPARPHSHHTLAPDQGNGKSLKACVRGFLVRRQFQSLRAEYEAIVREV 120

Query: 121 EGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEE 180
           EGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEE
Sbjct: 121 EGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEE 180

Query: 181 MVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQL 240
           MVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQL
Sbjct: 181 MVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQL 240

Query: 241 QELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERD 300
           QELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERD
Sbjct: 241 QELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERD 300

Query: 301 QSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQKNIAGAKCREPCYSK 360
           QSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQKNIAGAKCREPCYSK
Sbjct: 301 QSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQKNIAGAKCREPCYSK 360

Query: 361 SGPPSSIPSNSQALGDRLTKGPDDGRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRT 420
           SGPPSSIPSNSQALGDRLTKGPDDGRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRT
Sbjct: 361 SGPPSSIPSNSQALGDRLTKGPDDGRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRT 420

Query: 421 QLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVLDLWRT 480
           QLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVLDLWRT
Sbjct: 421 QLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVLDLWRT 480

Query: 481 KPPKGQAPTDRSSRDGTSNEPSHEGQKKQRTIPWRSKSPEILSSTKAGCTGEEQWRGRPW 540
           KPPKGQAPTDRSSRDGTSNEPSHEGQKKQRTIPWRSKSPEILSSTKAGCTGEEQWRGRPW
Sbjct: 481 KPPKGQAPTDRSSRDGTSNEPSHEGQKKQRTIPWRSKSPEILSSTKAGCTGEEQWRGRPW 540

Query: 541 KTEPPG 546
           KTEPPG
Sbjct: 541 KTEPPG 546


>gi|229892326 IQ motif containing C isoform 2 [Homo sapiens]
          Length = 466

 Score =  948 bits (2450), Expect = 0.0
 Identities = 453/455 (99%), Positives = 455/455 (100%)

Query: 92  SLKACVRGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWK 151
           +L+ACVRGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWK
Sbjct: 12  ALQACVRGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWK 71

Query: 152 AGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRK 211
           AGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRK
Sbjct: 72  AGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRK 131

Query: 212 PSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLK 271
           PSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLK
Sbjct: 132 PSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLK 191

Query: 272 QTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRV 331
           QTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRV
Sbjct: 192 QTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRV 251

Query: 332 KSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQTFGG 391
           KSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQTFGG
Sbjct: 252 KSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQTFGG 311

Query: 392 TCLLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRT 451
           TCLLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRT
Sbjct: 312 TCLLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRT 371

Query: 452 QELGLSEDHIIWDGTLGGPEHSVLDLWRTKPPKGQAPTDRSSRDGTSNEPSHEGQKKQRT 511
           QELGLSEDHIIWDGTLGGPEHSVLDLWRTKPPKGQAPTDRSSRDGTSNEPSHEGQKKQRT
Sbjct: 372 QELGLSEDHIIWDGTLGGPEHSVLDLWRTKPPKGQAPTDRSSRDGTSNEPSHEGQKKQRT 431

Query: 512 IPWRSKSPEILSSTKAGCTGEEQWRGRPWKTEPPG 546
           IPWRSKSPEILSSTKAGCTGEEQWRGRPWKTEPPG
Sbjct: 432 IPWRSKSPEILSSTKAGCTGEEQWRGRPWKTEPPG 466



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 24/53 (45%), Positives = 28/53 (52%), Gaps = 13/53 (24%)

Query: 1  MEPELLVRKVSALQ--VRG--------RARGSQDFSFREI---MGSRTWTSQR 40
          MEPELLVRKVSALQ  VRG          R   +   RE+   +G+  WT  R
Sbjct: 1  MEPELLVRKVSALQACVRGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGR 53


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 45/185 (24%), Positives = 84/185 (45%), Gaps = 6/185 (3%)

Query: 169 CEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTR-MENPE 227
           CE+ E     EE + ++       +  LC +    L+ ++ R   QEK     R +E  E
Sbjct: 286 CEQEERLREQEERLCEQEERLREQEERLC-EQEERLREQEERLCEQEKLPGQERLLEEVE 344

Query: 228 ATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPR 287
              ++    + Q + L+  R    +E L  Q+ +  + E L  ++TL+  E   +RE  R
Sbjct: 345 KLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELER--LRELER 402

Query: 288 VFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGS-LATTQK 346
           + LE G +A    +++P +  E+ +  +++T +LEQ+     +        GS  A   +
Sbjct: 403 M-LELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAAR 461

Query: 347 NIAGA 351
            +AGA
Sbjct: 462 PVAGA 466


>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 479

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 51/232 (21%), Positives = 100/232 (43%), Gaps = 22/232 (9%)

Query: 109 LRAEYEAIVREVEGDLGTLQWTE--GRIPRPRFLPEKAKSHQT----WKAGDRVANPEQG 162
           LR E E++ R+++ ++   Q      R    R   ++ + H+      +  +R+   E+ 
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEER 228

Query: 163 LWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTR 222
           L     CE+ E     EE + ++       +  LC       + ++ R   QEK     R
Sbjct: 229 L-----CEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEE-RLCEQEKLPGQER 282

Query: 223 M-ENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRS----P 277
           + E  E   ++    + Q + L+  R    +E L  Q+ +  + E L  ++TLR      
Sbjct: 283 LLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLR 342

Query: 278 EAGPIREEPRV-----FLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQE 324
           E   +RE  R+      LE G +A    +++P +  E+ +  +++T +LEQ+
Sbjct: 343 ELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQ 394


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 37.4 bits (85), Expect = 0.036
 Identities = 34/190 (17%), Positives = 81/190 (42%), Gaps = 9/190 (4%)

Query: 143 KAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEA----TWEEMVLKKSGESSANQGSLCR 198
           + +  Q W+  +++ + EQ +W+     E + +     TW++    +  E    +    R
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599

Query: 199 DHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQ 258
           +    ++ +Q  K  +++ +   + E     ++++   + ++ E Q  +     E +W Q
Sbjct: 600 EEEEMMR-EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE-QEEKMWEQEEKMWEQ 657

Query: 259 QAINSRKEYLLLKQTLRSPEAGPIREE---PRVFLEHGEQACERDQSQPSAPLEDQSYRD 315
           Q +  +KE L   + ++  E    +EE    +  +E   Q  E+         E++S R+
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRE 717

Query: 316 RTTGELEQED 325
           R     E+E+
Sbjct: 718 REKKMREEEE 727



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 31/165 (18%), Positives = 67/165 (40%), Gaps = 16/165 (9%)

Query: 105 QFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLW 164
           Q + +R + E + R+ E       W + +  R +    + +  + W+  +R+   E+ + 
Sbjct: 360 QEEKMREQEEKMWRQEER-----LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM- 413

Query: 165 NHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTR---DTT 221
                   E E  WE++   +  +    Q    RD    +Q ++  +  ++K R   +T 
Sbjct: 414 -------REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 222 RMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKE 266
           R +  +   Q     + + +E Q  R     E LW Q+ +  ++E
Sbjct: 467 REQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 38/232 (16%), Positives = 95/232 (40%), Gaps = 30/232 (12%)

Query: 102 VRRQFQSLRAEYEAIVREVEG--DLGTLQWTEGRIPRPR---FLPEKAKSHQT--WKAGD 154
           +R + +++R + E + ++ E   +    +W + R+P  +   +  EK +  +   W+  +
Sbjct: 459 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518

Query: 155 RVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSS--WLQMKQNRKP 212
           ++ + E+ +W        + +  W +  +++  +    Q    RD     W Q ++  K 
Sbjct: 519 KIRDQEE-MWG-------QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK 570

Query: 213 SQEKTRDTTRMENPEATDQRLPHSQPQLQE-------------LQYHRSHLAMELLWLQQ 259
           +QE+ + T   E     ++R+   + +++E              Q  +     E +W Q+
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630

Query: 260 AINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQ 311
                +E  + +Q  +  E      E +   E  E+  E ++ Q    +++Q
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 36.6 bits (83), Expect = 0.061
 Identities = 86/386 (22%), Positives = 149/386 (38%), Gaps = 60/386 (15%)

Query: 170 EESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEAT 229
           EE E ++     +L   GES+  +  L       L  K+  +  + +  +  + EN E  
Sbjct: 329 EEEENDSGEPSSILNLPGESTLRRDFLRLQ----LANKERSEALRRQQLEQQQRENEEHK 384

Query: 230 DQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSP----EAGPIREE 285
            Q L   Q +++E +  R  L  +          R+E  L KQ  R      E    REE
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQ---------QRREKELRKQQEREQRRHYEEQMRREE 435

Query: 286 PRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQ 345
            R   EH EQ  +R Q      LE+Q   +R   +L+QE D  + V   H+        +
Sbjct: 436 ERRRAEH-EQEYKRKQ------LEEQRQAERLQRQLKQERD--YLVSLQHQRQEQRPVEK 486

Query: 346 KNIAGAK-----CREPCYSKSGP-----PSSIP--SNSQALGDRLTKGPDDGRQTFGGTC 393
           K +   K       +P ++K  P      S  P  + SQ++ ++ TKG    ++    T 
Sbjct: 487 KPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTS 546

Query: 394 LLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQE 453
                  ++  P    P      +   + S L ++ +I    P++     P         
Sbjct: 547 HRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISP--------- 597

Query: 454 LGLSEDHIIWDGTLGGP-------EHSVLDLWRTKP----PKGQAPTDRSSRDGT-SNEP 501
             L+  +   +G+  GP         S  DL RT+P    P  +  +  SS   T S++P
Sbjct: 598 -ALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQP 656

Query: 502 SHEGQKKQRTIPWRSKSPEILSSTKA 527
           S +G  +  +    S+   + +++K+
Sbjct: 657 SSQGGSQPGSQAGSSERTRVRANSKS 682


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 36.6 bits (83), Expect = 0.061
 Identities = 86/386 (22%), Positives = 149/386 (38%), Gaps = 60/386 (15%)

Query: 170 EESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEAT 229
           EE E ++     +L   GES+  +  L       L  K+  +  + +  +  + EN E  
Sbjct: 329 EEEENDSGEPSSILNLPGESTLRRDFLRLQ----LANKERSEALRRQQLEQQQRENEEHK 384

Query: 230 DQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSP----EAGPIREE 285
            Q L   Q +++E +  R  L  +          R+E  L KQ  R      E    REE
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQ---------QRREKELRKQQEREQRRHYEEQMRREE 435

Query: 286 PRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQ 345
            R   EH EQ  +R Q      LE+Q   +R   +L+QE D  + V   H+        +
Sbjct: 436 ERRRAEH-EQEYKRKQ------LEEQRQAERLQRQLKQERD--YLVSLQHQRQEQRPVEK 486

Query: 346 KNIAGAK-----CREPCYSKSGP-----PSSIP--SNSQALGDRLTKGPDDGRQTFGGTC 393
           K +   K       +P ++K  P      S  P  + SQ++ ++ TKG    ++    T 
Sbjct: 487 KPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQEALNVTS 546

Query: 394 LLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQE 453
                  ++  P    P      +   + S L ++ +I    P++     P         
Sbjct: 547 HRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVPQRTTSISP--------- 597

Query: 454 LGLSEDHIIWDGTLGGP-------EHSVLDLWRTKP----PKGQAPTDRSSRDGT-SNEP 501
             L+  +   +G+  GP         S  DL RT+P    P  +  +  SS   T S++P
Sbjct: 598 -ALARKNSPGNGSALGPRLGSQPIRASNPDLRRTEPILESPLQRTSSGSSSSSSTPSSQP 656

Query: 502 SHEGQKKQRTIPWRSKSPEILSSTKA 527
           S +G  +  +    S+   + +++K+
Sbjct: 657 SSQGGSQPGSQAGSSERTRVRANSKS 682


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 11/169 (6%)

Query: 204 LQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINS 263
           +Q +Q ++  ++K  +  R+E      +RL   + + + L+  R  L  E L  ++    
Sbjct: 142 IQRRQLQEQQRQKELERERLERERMERERLERERLERERLE--RERLEQEQLERERQERE 199

Query: 264 RKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQ 323
           R+E L  ++ L   E    R E +  L+   Q  ER + +    LE +        +LE+
Sbjct: 200 RQERLERQERLERQE----RLERQERLDRERQ--ERQERERLERLERERQERERQEQLER 253

Query: 324 EDDSCHRVK--SPHRSPGSLATTQKNIAG-AKCREPCYSKSGPPSSIPS 369
           E     R +  S   +P S+ T   ++ G +   EP    +  P+  PS
Sbjct: 254 EQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPS 302


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 39/169 (23%), Positives = 72/169 (42%), Gaps = 11/169 (6%)

Query: 204 LQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINS 263
           +Q +Q ++  ++K  +  R+E      +RL   + + + L+  R  L  E L  ++    
Sbjct: 142 IQRRQLQEQQRQKELERERLERERMERERLERERLERERLE--RERLEQEQLERERQERE 199

Query: 264 RKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQ 323
           R+E L  ++ L   E    R E +  L+   Q  ER + +    LE +        +LE+
Sbjct: 200 RQERLERQERLERQE----RLERQERLDRERQ--ERQERERLERLERERQERERQEQLER 253

Query: 324 EDDSCHRVK--SPHRSPGSLATTQKNIAG-AKCREPCYSKSGPPSSIPS 369
           E     R +  S   +P S+ T   ++ G +   EP    +  P+  PS
Sbjct: 254 EQLEWERERRISSAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPS 302


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 24/161 (14%)

Query: 170 EESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEAT 229
           EE E ++     +L   GES+  +  L       L  K+  +  + +  +  + EN E  
Sbjct: 329 EEEENDSGEPSSILNLPGESTLRRDFLRLQ----LANKERSEALRRQQLEQQQRENEEHK 384

Query: 230 DQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSP----EAGPIREE 285
            Q L   Q +++E +  R  L  +          R+E  L KQ  R      E    REE
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQ---------QRREKELRKQQEREQRRHYEEQMRREE 435

Query: 286 PRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDD 326
            R   EH EQ  +R Q      LE+Q   +R   +L+QE D
Sbjct: 436 ERRRAEH-EQEYKRKQ------LEEQRQAERLQRQLKQERD 469


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 24/161 (14%)

Query: 170 EESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEAT 229
           EE E ++     +L   GES+  +  L       L  K+  +  + +  +  + EN E  
Sbjct: 329 EEEENDSGEPSSILNLPGESTLRRDFLRLQ----LANKERSEALRRQQLEQQQRENEEHK 384

Query: 230 DQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSP----EAGPIREE 285
            Q L   Q +++E +  R  L  +          R+E  L KQ  R      E    REE
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQ---------QRREKELRKQQEREQRRHYEEQMRREE 435

Query: 286 PRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDD 326
            R   EH EQ  +R Q      LE+Q   +R   +L+QE D
Sbjct: 436 ERRRAEH-EQEYKRKQ------LEEQRQAERLQRQLKQERD 469


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 35.0 bits (79), Expect = 0.18
 Identities = 45/171 (26%), Positives = 67/171 (39%), Gaps = 11/171 (6%)

Query: 265  KEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQE 324
            KE LLL++    P AG   +EP+  L  G        S+P AP     +   T G+L QE
Sbjct: 2478 KEALLLRE---DPGAGGW-QEPKSLLSLGSYPPAAGSSEPKAP-----WPKATDGDLAQE 2528

Query: 325  DDSCHRVKSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDD 384
                   +    +P S    Q    GA+  E   S S   SS  S+S + G   T+G ++
Sbjct: 2529 PGPGLTFEDSG-NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSE-TEGEEE 2586

Query: 385  GRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMS 435
            G +   G C    +     + R   P +     S +  S+    S+    S
Sbjct: 2587 GDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS 2637


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 31/189 (16%), Positives = 76/189 (40%), Gaps = 9/189 (4%)

Query: 143 KAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSS 202
           + +  Q W+  +++ + EQ +W+       + E   E+    +  +    Q    R+   
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541

Query: 203 WLQMKQNRKPSQEKTRDTTRMENPE---ATDQRLPHSQPQLQELQYHRSHLAMELLWLQQ 259
             + ++     +EK R+  RM   E     ++ +   Q +  + Q  +     E +W Q+
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601

Query: 260 AINSRKEYLLLKQTLR---SPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDR 316
                +E  + +Q  +     E   ++E+  +  E  E+  E+++       +++  R++
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE---QEEKMREQ 658

Query: 317 TTGELEQED 325
                EQE+
Sbjct: 659 EEKMREQEE 667



 Score = 30.8 bits (68), Expect = 3.3
 Identities = 40/239 (16%), Positives = 92/239 (38%), Gaps = 31/239 (12%)

Query: 105 QFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLW 164
           Q + +R + E + R+ E       W + +  R +    + +  + W+  +R+   E+ + 
Sbjct: 322 QEEKMREQEEKMWRQEER-----LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM- 375

Query: 165 NHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRME 224
                   E E  WE+    +  E    +    R+      M++  +  Q++  +    E
Sbjct: 376 -------REQEKMWEQEEKMQEEERIREREKKMREEEE--TMREQEEKMQKQEENMWEQE 426

Query: 225 NPEATDQRLPHSQPQLQELQYHRSH-----------LAMELLWLQQAINSRKEYLLLKQT 273
             E   QRLP  + +L E +  +                E +W Q+    R+E +  ++ 
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486

Query: 274 LRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVK 332
               +   +R++ +   +  E+  E+D+      L ++  R R   ++ Q+++     K
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDER-----LREKEERMREQKKMWQQEEKMREEK 540


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 34.7 bits (78), Expect = 0.23
 Identities = 37/138 (26%), Positives = 61/138 (44%), Gaps = 12/138 (8%)

Query: 203 WLQMKQN-RKPSQEKTRDTTRMENPEATDQRLPHSQPQ--LQELQYHRSHLAMELLWLQQ 259
           WL++++  R+  QE+     R E  E  +QRL   + +  LQ+       L  E    ++
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547

Query: 260 AINSRKEYLLLKQTLRSPEAGPIREEPRVFL-----EHGEQACERDQSQPSAPLEDQSYR 314
            +  R+E   L+Q  R       +EE R  L     E  +Q  +R+Q +    LE +  R
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE---RLEQRLKR 604

Query: 315 DRTTGELEQEDDSCHRVK 332
           +     LEQE+    R+K
Sbjct: 605 EEVE-RLEQEERREQRLK 621



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 48/234 (20%), Positives = 87/234 (37%), Gaps = 19/234 (8%)

Query: 98  RGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVA 157
           R  ++R++ + L+ E     RE++ +   L+    ++ R     E+ +  Q  +   R  
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQLR----KLERQELRRERQEEEQQQQRLRR-- 302

Query: 158 NPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKT 217
             EQ L      E  E +    E   ++  +    +  L R+     + +  R+  +E+ 
Sbjct: 303 --EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360

Query: 218 RDTTRMENPEAT-------DQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLL 270
               R E  E         +Q+L   Q   +E Q  R         L++    R+E  L 
Sbjct: 361 EQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420

Query: 271 KQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQE 324
           ++     E    R E +   E  EQ  +R+Q +      D   R+  T   EQE
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEE----RRDWLKREEETERHEQE 470



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 19/169 (11%)

Query: 170 EESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQE---KTRDTTRMENP 226
           EE   E    E  LK+  E   +Q     +     ++K+ ++   E   K  +  R+E  
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQE 613

Query: 227 EATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLR-----SPEAGP 281
           E  +QRL   +P+ +  Q        +LL  ++    R++ L  +Q  R       E   
Sbjct: 614 ERREQRLKREEPEEERRQ--------QLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665

Query: 282 IREEPRVFLEHGEQACER---DQSQPSAPLEDQSYRDRTTGELEQEDDS 327
            R E R+  EH E+  E+   ++ Q  A    +S   +   +LE E D+
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 28/133 (21%), Positives = 54/133 (40%), Gaps = 8/133 (6%)

Query: 198  RDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQL----QELQYHRSHLAME 253
            R+     + +++RK  +E+ +   +  + +  +Q L   +P+     +E Q HR     +
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532

Query: 254  LLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSY 313
             L  +Q +  ++      Q  R       REE ++  E  EQ   R +      LE+Q  
Sbjct: 1533 FLQEEQQLRRQER----GQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588

Query: 314  RDRTTGELEQEDD 326
            R +       ED+
Sbjct: 1589 RRQEQERKFMEDE 1601



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 42/199 (21%), Positives = 76/199 (38%), Gaps = 14/199 (7%)

Query: 136 RPRFLPEKAKSHQTWKAGDRVANPEQGLWN-------HFPCEESEGEATWEEMVLKKSGE 188
           R R   E  +  Q W+  +     E+ L +        FP EE       E + L++ G 
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRR--ELLELRRKGR 223

Query: 189 SSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRS 248
               Q    R      ++ Q  +  + + R+T   +  E   +  P  Q +LQE +    
Sbjct: 224 EEKQQQRRERQD----RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279

Query: 249 HLA-MELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAP 307
            L   EL   +Q    +++ L  +Q LR  +    RE+     E  E+  ++++ +    
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339

Query: 308 LEDQSYRDRTTGELEQEDD 326
             +Q  R       EQE++
Sbjct: 340 RREQEERREQQLRREQEEE 358


>gi|44890059 involucrin [Homo sapiens]
          Length = 585

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 77/372 (20%), Positives = 137/372 (36%), Gaps = 41/372 (11%)

Query: 168 PCEESEGEATWEEMVLKKSGESSANQG---SLCRDHSSWLQMKQNRKPSQEKTRDTTRME 224
           PC++   E   E    ++    +A +G     C       Q ++ ++   E+  +  + E
Sbjct: 43  PCQKVPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQKEPQEQELQQQHWEQHEEYQKAE 102

Query: 225 NPEAT-----DQRLPHSQPQLQE-LQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPE 278
           NPE        QR      QL+E  +     L  EL+   + +  +KE LL    L   +
Sbjct: 103 NPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLL---ELPEQQ 159

Query: 279 AGPIR--EEPRVFLEHGEQA------CERDQSQPSAPLEDQSYRD---RTTGELEQEDDS 327
            G ++  E+    L+H EQ        E+ + Q   P + +   +   +  G+LE  +  
Sbjct: 160 EGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQQ 219

Query: 328 CHRVKSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQ 387
             +++ P +  G L   Q+     +  E           +  + Q  G        +G+ 
Sbjct: 220 EGQLELPEQQEGQLELPQQQEGQLELSEQ------QEGQLELSEQQEGQLKHLEHQEGQL 273

Query: 388 TFGGTCLLQMKILEDQTP--RGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPD 445
                 + Q+K LE Q    + L  +   P     Q+  L +    +E  P+ L+ +E  
Sbjct: 274 EVPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQL-KHLEQQEGQPKHLEQQEGQ 332

Query: 446 CRTVRTQELGLSE--------DHIIW-DGTLGGPEHSVLDLWRTKPPKGQAPTDRSSRDG 496
              +  QE  L          +H+   +G LG PE  VL L + +  +GQ          
Sbjct: 333 LEQLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQ 392

Query: 497 TSNEPSHEGQKK 508
             +    EGQ K
Sbjct: 393 LKHLVQQEGQLK 404


>gi|33354279 hypothetical protein LOC55425 [Homo sapiens]
          Length = 340

 Score = 34.3 bits (77), Expect = 0.30
 Identities = 47/219 (21%), Positives = 84/219 (38%), Gaps = 40/219 (18%)

Query: 276 SPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGE-----------LEQE 324
           S ++    E+     E G Q  E D S P+A  + ++  D    +            +++
Sbjct: 43  SSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQ 102

Query: 325 DDSCHR-VKSPHRSPGSLATTQKNIAGAKCREPCYSKS---------GP-PSSIPSN--- 370
           DDS  R +  P   PG + +TQK+  G    +P   ++         GP P+  P N   
Sbjct: 103 DDSPPRPIIGPALPPGFIKSTQKSDKGRD--DPGQQETDSSEDEDIIGPMPAKGPVNYNV 160

Query: 371 -------SQALGDRLTKGPDDGRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRTQLS 423
                  +Q + ++LTKG DD  +       +  +    + P  +K     PR  + +  
Sbjct: 161 TTEFEKRAQRMKEKLTKGDDDSSKP------IVRESWMTELPPEMKDFGLGPRTFKRRAD 214

Query: 424 ALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHII 462
               D +I   +P   + K  + +  R       E+HI+
Sbjct: 215 DTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHIL 253


>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
          Length = 5120

 Score = 33.9 bits (76), Expect = 0.39
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 7/103 (6%)

Query: 184  KKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQEL 243
            KK  E   ++G+L ++       K+  +   E+  D    E     D+ +  +  + ++ 
Sbjct: 2279 KKEQEERKHKGALEKE-------KERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331

Query: 244  QYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEP 286
            +  R    M+   LQQ +  +KE   LK+ ++  + GPI+EEP
Sbjct: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEP 2374


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 39/179 (21%), Positives = 71/179 (39%), Gaps = 19/179 (10%)

Query: 198 RDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWL 257
           R  S   Q +Q+R P++E+ R  +R  + E  + R   S  + ++ +  RS         
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEER-EHRQSRSPSKERDRRRWRSPSKERERRQ 583

Query: 258 QQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRT 317
            ++ +  +++       RSP        PR        + E+  S+   P ++ ++    
Sbjct: 584 SRSSSEERDH----SRSRSPNKQSGYSRPRA------SSKEKAHSRSRTPSKEGNHSQSR 633

Query: 318 TGELEQEDDSCHRVKSPH--RSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQAL 374
           T   E +       +SP   RSP   ++  +N      R P  + S  PS+ PS  Q L
Sbjct: 634 TSSKESDPSQSTVPRSPDWKRSPTRTSSLSQN------RTPSKTSSHSPSTFPSGGQTL 686


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 31/181 (17%), Positives = 72/181 (39%), Gaps = 21/181 (11%)

Query: 143 KAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSS 202
           + +  + W+  +++   E+ +W        + E  WE+  L +  E    Q    R+   
Sbjct: 36  REQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLRE--- 92

Query: 203 WLQMKQNRKPSQEKTRDTTRM-ENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAI 261
               K+ R   Q+  +   +M E  +  ++++   + ++QE +        E++W Q+  
Sbjct: 93  ----KEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQE--------EMMWEQEEK 140

Query: 262 NSRKEYLLLKQ--TLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTG 319
              +E  + +Q   +R  E     +E ++    G++   RD         + S +D  T 
Sbjct: 141 MQEQEEKMWEQEEKMREQEEKMREQEEKM---QGQEEKMRDVEPAGGEAGEGSPQDNPTA 197

Query: 320 E 320
           +
Sbjct: 198 Q 198


>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
          Length = 861

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 20/99 (20%), Positives = 39/99 (39%), Gaps = 1/99 (1%)

Query: 416 RKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVL 475
           RK +  L      +  +E   +  +H     R +   + G ++D ++      GPE  V 
Sbjct: 328 RKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVA 387

Query: 476 DLWRTKPPKGQAPTDRSSRD-GTSNEPSHEGQKKQRTIP 513
              +++PP    P   S+    +S   +H G   +  +P
Sbjct: 388 SPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLP 426


>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
          Length = 738

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 20/99 (20%), Positives = 39/99 (39%), Gaps = 1/99 (1%)

Query: 416 RKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVL 475
           RK +  L      +  +E   +  +H     R +   + G ++D ++      GPE  V 
Sbjct: 204 RKKQFDLLLAEHKAKSREKEVKDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVA 263

Query: 476 DLWRTKPPKGQAPTDRSSRD-GTSNEPSHEGQKKQRTIP 513
              +++PP    P   S+    +S   +H G   +  +P
Sbjct: 264 SPAKSRPPNSVLPRPSSANSISSSTSSNHSGHTPEPPLP 302


>gi|148727255 microtubule associated serine/threonine kinase family
            member 4 isoform a [Homo sapiens]
          Length = 2434

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 48/250 (19%), Positives = 91/250 (36%), Gaps = 20/250 (8%)

Query: 142  EKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHS 201
            EK    ++ + G   A  E+       C E   E  + E    K+ ++S N  S+ R H 
Sbjct: 1777 EKPGLRESSERGPPTARSERSAARADTCREPSMELCFPETA--KTSDNSKNLLSVGRTHP 1834

Query: 202  SWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAME--LLWLQQ 259
             +    Q  + +      T   + P           P       H + +  E  L  +++
Sbjct: 1835 DFYTQTQAMEKAWAPGGKTNHKDGPGEA------RPPPRDNSSLHSAGIPCEKELGKVRR 1888

Query: 260  AINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTG 319
             +  + E LL +++L+ P     + E        ++   ++  +   PL+      R   
Sbjct: 1889 GVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKEQPLQ------RHPS 1942

Query: 320  ELEQEDDSCHRVKSP----HRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALG 375
             +     +   + SP    H S  S A+ ++  A     EP  S   PP  + ++S++  
Sbjct: 1943 SIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAKPSTAEPSSSPQDPPKPVAAHSESSS 2002

Query: 376  DRLTKGPDDG 385
             +   GPD G
Sbjct: 2003 HKPRPGPDPG 2012


>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
           isoform 2 [Homo sapiens]
          Length = 470

 Score = 33.5 bits (75), Expect = 0.51
 Identities = 44/210 (20%), Positives = 88/210 (41%), Gaps = 29/210 (13%)

Query: 135 PRPRFLPEKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQG 194
           P  +   +K K   T K G    +PE   +      ++E   +  E +L++    + N+ 
Sbjct: 135 PFQKAAKKKTKKRDT-KVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEI--EAKNRE 191

Query: 195 SLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMEL 254
            + +  +  L   +N++  +E+ R+  R    E   QR    +                 
Sbjct: 192 LIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRK---------------- 235

Query: 255 LWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFL----EHGEQACERDQSQPSAPLED 310
            W ++    RK+   LK+  R PE   +++EP++ L    E G++  E D+ + +  L+ 
Sbjct: 236 -WKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEK-ELDKREKAKKLDK 293

Query: 311 QSYRD-RTTGE---LEQEDDSCHRVKSPHR 336
           ++  D R +G+   L +  DS  + + P R
Sbjct: 294 ENLSDERASGQSCTLPKRSDSELKDEKPKR 323


>gi|224458301 family with sequence similarity 186, member A [Homo
           sapiens]
          Length = 2351

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 25/131 (19%), Positives = 58/131 (44%), Gaps = 5/131 (3%)

Query: 199 DHSSWLQMKQNRKPSQEKTR----DTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMEL 254
           +  +WLQMK+ ++  Q + +    +  + E  +AT ++    + Q Q  Q         L
Sbjct: 863 EKKAWLQMKEGKQEQQSQKQWQEEEMWKEEQKQATPKQAEQEEKQKQRGQEEEELPKSSL 922

Query: 255 LWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYR 314
             L++     K   LL +   + +   I++E +    H  +   +++ +P   LED   +
Sbjct: 923 QRLEEGTQKMKTQGLLLEK-ENGQMRQIQKEAKHLGPHRRREKGKEKQKPERGLEDLERQ 981

Query: 315 DRTTGELEQED 325
            +T  +++ ++
Sbjct: 982 IKTKDQMQMKE 992


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 52/257 (20%), Positives = 103/257 (40%), Gaps = 41/257 (15%)

Query: 102  VRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQ 161
            VR+Q ++ + E ++ + E E    +L+  EG+I R +    + K+    K  ++    EQ
Sbjct: 1529 VRKQLEAEKMELQSALEEAEA---SLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1585

Query: 162  GLWNHFPCEES-------EGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNR---- 210
               NH    +S       E  +  E + +KK  E   N+  +   H++ +  +  +    
Sbjct: 1586 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1645

Query: 211  -----KPSQEKTRDTTR-----MENPEATDQRLPHSQPQLQEL-----QYHRSHLAMELL 255
                 K +Q +  D  R      EN    ++R    Q +L+EL     Q  RS    E  
Sbjct: 1646 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQE 1705

Query: 256  WLQ-----QAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLED 310
             ++     Q ++S+   L+ ++     +   ++ E    +E   Q C   + +    + D
Sbjct: 1706 LIETSERVQLLHSQNTSLINQKKKMDADLSQLQTE----VEEAVQECRNAEEKAKKAITD 1761

Query: 311  QSYRDRTTGELEQEDDS 327
             +       EL++E D+
Sbjct: 1762 AA---MMAEELKKEQDT 1775


>gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens]
          Length = 1834

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 7/78 (8%)

Query: 180  EMVLKKSGESSA--NQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRM--ENPEATDQRLPH 235
            E VL++  E +   N+GSL R  + WL   +   PS+  T DT+ +    P A+  R   
Sbjct: 1211 EAVLQQEDEGALPENRGSLGRRGAPWLFCDRESSPSEASTTDTSWLVPATPLASRSRDCS 1270

Query: 236  SQPQLQELQYHRSHLAME 253
            SQ Q+  L   RS LA++
Sbjct: 1271 SQTQISSL---RSGLAVQ 1285


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 32.7 bits (73), Expect = 0.88
 Identities = 52/226 (23%), Positives = 81/226 (35%), Gaps = 41/226 (18%)

Query: 170 EESEGEATWE---EMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENP 226
           E SE EA+ E   EM  +   +      S  +++ S L M++  +  +EK  +      P
Sbjct: 415 EPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEP----QP 470

Query: 227 EATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPE---AGPIR 283
           E   Q  P SQPQLQ                   + S+ + +L  Q    PE      ++
Sbjct: 471 EPVAQPQPQSQPQLQ-------------------LQSQSQPVLQSQPPSQPEDLSLAVLQ 511

Query: 284 EEPRVFLEHGEQACER-DQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLA 342
             P+V  E G    ER D    S  L +       T   E +  +  R +S  R+    +
Sbjct: 512 PTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTS 571

Query: 343 TTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQT 388
            ++             S S   SS  S S + G   + G    R +
Sbjct: 572 KSRSR-----------SSSSSSSSSSSTSSSSGSSSSSGSSSSRSS 606


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 5/111 (4%)

Query: 215 EKTRDTTR-MENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQT 273
           E+TR   R ++  +   Q  P  QPQ ++LQ  + HL ++    QQ     ++ L   Q 
Sbjct: 80  EETRPGQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQ----QQPQQDGQQQLSQLQQ 135

Query: 274 LRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQE 324
            +         +P + L H +Q  +  Q Q    L+ Q  + +T    EQ+
Sbjct: 136 EKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQ 186


>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
          Length = 1163

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 1/88 (1%)

Query: 293 GEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQKNIAGAK 352
           GEQ C++   + +     +     + G     DDS     S   S GS + ++ + + ++
Sbjct: 394 GEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS-ESSSGSDSESESSSSDSE 452

Query: 353 CREPCYSKSGPPSSIPSNSQALGDRLTK 380
             EP  S S  P   P+N   L + L K
Sbjct: 453 ANEPSQSASPEPEPPPTNKWQLDNWLNK 480


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 51/203 (25%), Positives = 75/203 (36%), Gaps = 42/203 (20%)

Query: 214   QEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQT 273
             +E T D  R+  P+          P L+EL+ +R  +        +A+N   E      T
Sbjct: 15745 EEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRV--------KAVNEAGESEPSDTT 15796

Query: 274   LRSPEAGPIREEPRVFLEHGEQAC-------------------------ERDQSQPSAPL 308
                P A  I+EEP VF++ G Q C                         E D     A +
Sbjct: 15797 GEIP-ATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKA-M 15854

Query: 309   EDQSYRDRTTGELEQEDDSCHRV--KSPHRSPGSLATTQKNIAG---AKCREPCYSKSGP 363
             +D  +      +LE  ++S   +  +      G  + T KN AG   A CR       GP
Sbjct: 15855 KDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGP 15914

Query: 364   PSSIPSNSQALGD-RLT-KGPDD 384
             P  +  +    G  RL+ K PDD
Sbjct: 15915 PKDLKVSDITRGSCRLSWKMPDD 15937


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,959,158
Number of Sequences: 37866
Number of extensions: 1377431
Number of successful extensions: 3703
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 3609
Number of HSP's gapped (non-prelim): 186
length of query: 546
length of database: 18,247,518
effective HSP length: 107
effective length of query: 439
effective length of database: 14,195,856
effective search space: 6231980784
effective search space used: 6231980784
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.