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Search of human proteins with 22779936
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22779936 WAP four-disulfide core domain 6 precursor [Homo
sapiens]
(86 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22779936 WAP four-disulfide core domain 6 precursor [Homo sap... 186 3e-48
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP... 90 3e-19
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP... 64 2e-11
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa... 44 3e-05
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa... 44 3e-05
gi|20069858 WAP four-disulfide core domain 12 precursor [Homo sa... 41 2e-04
gi|4507065 secretory leukocyte peptidase inhibitor precursor [Ho... 38 0.002
gi|4505787 elafin preproprotein [Homo sapiens] 33 0.063
gi|21717822 WAP four-disulfide core domain 5 precursor [Homo sap... 32 0.14
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap... 32 0.14
gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens] 31 0.18
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens] 31 0.18
gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap... 31 0.24
gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sa... 31 0.24
gi|40807489 egf-like module containing, mucin-like, hormone rece... 30 0.53
gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens] 29 0.70
gi|56699495 WAP four-disulfide core domain 2 precursor [Homo sap... 28 1.2
gi|31881740 solute carrier family 12 (potassium/chloride transpo... 28 2.0
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 27 2.7
gi|31543535 R3H domain containing 1 [Homo sapiens] 27 2.7
gi|21703706 WAP four-disulfide core domain 10A precursor [Homo s... 27 4.5
gi|194328809 latent transforming growth factor beta binding prot... 26 5.9
gi|18497288 latent transforming growth factor beta binding prote... 26 5.9
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur... 26 7.7
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur... 26 7.7
gi|59676593 PRAME family member 7 [Homo sapiens] 26 7.7
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 26 7.7
gi|59676587 PRAME family member 8 [Homo sapiens] 26 7.7
>gi|22779936 WAP four-disulfide core domain 6 precursor [Homo
sapiens]
Length = 86
Score = 186 bits (472), Expect = 3e-48
Identities = 86/86 (100%), Positives = 86/86 (100%)
Query: 1 MGLSGLLPILVPFILLGDIQEPGHAEGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKC 60
MGLSGLLPILVPFILLGDIQEPGHAEGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKC
Sbjct: 1 MGLSGLLPILVPFILLGDIQEPGHAEGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKC 60
Query: 61 CPFSRGKKCLDFRKVSLTLYHKEELE 86
CPFSRGKKCLDFRKVSLTLYHKEELE
Sbjct: 61 CPFSRGKKCLDFRKVSLTLYHKEELE 86
>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 1 precursor [Homo sapiens]
Length = 133
Score = 90.1 bits (222), Expect = 3e-19
Identities = 40/74 (54%), Positives = 52/74 (70%)
Query: 1 MGLSGLLPILVPFILLGDIQEPGHAEGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKC 60
MG SGLL +LV F+LL ++Q PG + + + CPKI+ ECE +E D CTK R C +N KC
Sbjct: 1 MGSSGLLSLLVLFVLLANVQGPGLTDWLFPRRCPKIREECEFQERDVCTKDRQCQDNKKC 60
Query: 61 CPFSRGKKCLDFRK 74
C FS GKKCLD ++
Sbjct: 61 CVFSCGKKCLDLKQ 74
>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
domains 1 isoform 2 [Homo sapiens]
Length = 117
Score = 64.3 bits (155), Expect = 2e-11
Identities = 26/42 (61%), Positives = 31/42 (73%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRK 74
CPKI+ ECE +E D CTK R C +N KCC FS GKKCLD ++
Sbjct: 17 CPKIREECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQ 58
>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 43.9 bits (102), Expect = 3e-05
Identities = 18/39 (46%), Positives = 22/39 (56%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLD 71
CPK ++ C E D C DC E KCC F+ KKC+D
Sbjct: 51 CPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMD 89
Score = 31.2 bits (69), Expect = 0.18
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRK 74
CP+ + C + +C + +CP KCC G KC+D R+
Sbjct: 201 CPRKPLLCTKIDKPKCLQDEECPLVEKCCSHC-GLKCMDPRR 241
>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
sapiens]
Length = 241
Score = 43.9 bits (102), Expect = 3e-05
Identities = 18/39 (46%), Positives = 22/39 (56%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLD 71
CPK ++ C E D C DC E KCC F+ KKC+D
Sbjct: 51 CPKERLTCTTELPDSCNTDFDCKEYQKCCFFACQKKCMD 89
Score = 31.2 bits (69), Expect = 0.18
Identities = 14/42 (33%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRK 74
CP+ + C + +C + +CP KCC G KC+D R+
Sbjct: 201 CPRKPLLCTKIDKPKCLQDEECPLVEKCCSHC-GLKCMDPRR 241
>gi|20069858 WAP four-disulfide core domain 12 precursor [Homo
sapiens]
Length = 111
Score = 40.8 bits (94), Expect = 2e-04
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 1/71 (1%)
Query: 1 MGLSGLLPILVPFILLGDIQEPGHAEGI-LGKPCPKIKVECEVEEIDQCTKPRDCPENMK 59
MG S L ++V +L+ + G EGI CP V C + QC +DC K
Sbjct: 1 MGSSSFLVLMVSLVLVTLVAVEGVKEGIEKAGVCPADNVRCFKSDPPQCHTDQDCLGERK 60
Query: 60 CCPFSRGKKCL 70
CC G KC+
Sbjct: 61 CCYLHCGFKCV 71
>gi|4507065 secretory leukocyte peptidase inhibitor precursor
[Homo sapiens]
Length = 132
Score = 38.1 bits (87), Expect = 0.002
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 3/74 (4%)
Query: 1 MGLSGLLPILVPFIL--LGDIQEPGHAEGILGKPCP-KIKVECEVEEIDQCTKPRDCPEN 57
M SGL P LV L L G + CP K +C + +C CP
Sbjct: 1 MKSSGLFPFLVLLALGTLAPWAVEGSGKSFKAGVCPPKKSAQCLRYKKPECQSDWQCPGK 60
Query: 58 MKCCPFSRGKKCLD 71
+CCP + G KCLD
Sbjct: 61 KRCCPDTCGIKCLD 74
>gi|4505787 elafin preproprotein [Homo sapiens]
Length = 117
Score = 32.7 bits (73), Expect = 0.063
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 33 CPKIKVECEV-EEIDQCTKPRDCPENMKCCPFSRGKKC 69
CP I + C + ++C K DCP KCC S G C
Sbjct: 76 CPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMAC 113
>gi|21717822 WAP four-disulfide core domain 5 precursor [Homo
sapiens]
Length = 123
Score = 31.6 bits (70), Expect = 0.14
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 23 GHAEGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRKVSLTLYHK 82
G +G CP C + DQC + CP KCC + ++C+ V L +
Sbjct: 24 GRKKGEKSGGCPPDDGPCLLSVPDQCVEDSQCPLTRKCCYRACFRQCVPRVSVKLGSCPE 83
Query: 83 EEL 85
++L
Sbjct: 84 DQL 86
Score = 30.0 bits (66), Expect = 0.41
Identities = 12/39 (30%), Positives = 18/39 (46%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLD 71
CP+ ++ C C K DC +CC + G+ C D
Sbjct: 81 CPEDQLRCLSPMNHLCHKDSDCSGKKRCCHSACGRDCRD 119
>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
sapiens]
Length = 231
Score = 31.6 bits (70), Expect = 0.14
Identities = 14/41 (34%), Positives = 18/41 (43%), Gaps = 4/41 (9%)
Query: 30 GKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCL 70
G CP + CE + C CP+ KCC G+ CL
Sbjct: 123 GGECPADPLPCE----ELCDGDASCPQGHKCCSTGCGRTCL 159
Score = 28.5 bits (62), Expect = 1.2
Identities = 14/42 (33%), Positives = 17/42 (40%), Gaps = 4/42 (9%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRK 74
CP K C+ + C CP KCC G+ C D K
Sbjct: 33 CPPHKNPCK----ELCQGDELCPAEQKCCTTGCGRICRDIPK 70
Score = 26.6 bits (57), Expect = 4.5
Identities = 12/42 (28%), Positives = 18/42 (42%), Gaps = 6/42 (14%)
Query: 31 KPCPKI--KVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCL 70
+ CP++ K C + +C CP KCC K C+
Sbjct: 74 RDCPRVIRKQSC----LKRCITDETCPGVKKCCTLGCNKSCV 111
>gi|145580584 uromodulin-like 1 isoform 1 precursor [Homo sapiens]
Length = 1318
Score = 31.2 bits (69), Expect = 0.18
Identities = 11/23 (47%), Positives = 15/23 (65%)
Query: 48 CTKPRDCPENMKCCPFSRGKKCL 70
C+ DCP KCCP+S G+ C+
Sbjct: 133 CSLDIDCPGLEKCCPWSGGRYCM 155
>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
Length = 1446
Score = 31.2 bits (69), Expect = 0.18
Identities = 11/23 (47%), Positives = 15/23 (65%)
Query: 48 CTKPRDCPENMKCCPFSRGKKCL 70
C+ DCP KCCP+S G+ C+
Sbjct: 133 CSLDIDCPGLEKCCPWSGGRYCM 155
>gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo
sapiens]
Length = 1048
Score = 30.8 bits (68), Expect = 0.24
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
Query: 3 LSGLLPILVPFILLGDIQEP-----GHAEGILGKPCPKIKVECEVEEID 46
+ G +PI P + P G +LG P P+IKV+ EVE +D
Sbjct: 744 IPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMD 792
>gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo
sapiens]
Length = 1083
Score = 30.8 bits (68), Expect = 0.24
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
Query: 3 LSGLLPILVPFILLGDIQEP-----GHAEGILGKPCPKIKVECEVEEID 46
+ G +PI P + P G +LG P P+IKV+ EVE +D
Sbjct: 779 IPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMD 827
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 29.6 bits (65), Expect = 0.53
Identities = 9/18 (50%), Positives = 13/18 (72%)
Query: 43 EEIDQCTKPRDCPENMKC 60
E++D+C PR CPE+ C
Sbjct: 171 EDVDECADPRACPEHATC 188
>gi|239755460 PREDICTED: similar to mucin, partial [Homo sapiens]
Length = 1064
Score = 29.3 bits (64), Expect = 0.70
Identities = 14/50 (28%), Positives = 21/50 (42%), Gaps = 3/50 (6%)
Query: 30 GKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRKVSLTL 79
G+ CP+ C +C KP CPE + P + C + S T+
Sbjct: 746 GQCCPQYSCACNTS---RCPKPVGCPEGARAIPTYQEGACCPVQNCSWTV 792
>gi|56699495 WAP four-disulfide core domain 2 precursor [Homo
sapiens]
Length = 124
Score = 28.5 bits (62), Expect = 1.2
Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 2/37 (5%)
Query: 33 CPKIKVECEVEEI--DQCTKPRDCPENMKCCPFSRGK 67
CP++ + + DQC CP MKCC GK
Sbjct: 80 CPQVNINFPQLGLCRDQCQVDSQCPGQMKCCRNGCGK 116
Score = 26.9 bits (58), Expect = 3.5
Identities = 8/29 (27%), Positives = 17/29 (58%), Gaps = 2/29 (6%)
Query: 33 CPKIKVECEVEEIDQCTKPRDCPENMKCC 61
CP+++ + + +C +C +N+KCC
Sbjct: 36 CPELQADQNCTQ--ECVSDSECADNLKCC 62
>gi|31881740 solute carrier family 12 (potassium/chloride
transporters), member 9 [Homo sapiens]
Length = 914
Score = 27.7 bits (60), Expect = 2.0
Identities = 12/33 (36%), Positives = 20/33 (60%)
Query: 13 FILLGDIQEPGHAEGILGKPCPKIKVECEVEEI 45
F+ LG + PG AEG L ++++ EV+E+
Sbjct: 769 FLCLGPREAPGAAEGRLRALLSQLRIRAEVQEV 801
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 27.3 bits (59), Expect = 2.7
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 1/35 (2%)
Query: 38 VECEVEEIDQCT-KPRDCPENMKCCPFSRGKKCLD 71
V C +D CT KPRD P N C S KK +
Sbjct: 30 VTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATE 64
>gi|31543535 R3H domain containing 1 [Homo sapiens]
Length = 1099
Score = 27.3 bits (59), Expect = 2.7
Identities = 11/35 (31%), Positives = 17/35 (48%)
Query: 51 PRDCPENMKCCPFSRGKKCLDFRKVSLTLYHKEEL 85
P +N C RG+KC++F V + H +L
Sbjct: 848 PPQWKQNKYYCDHQRGQKCVEFSSVDNIVQHSPQL 882
>gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
sapiens]
Length = 79
Score = 26.6 bits (57), Expect = 4.5
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 6/71 (8%)
Query: 6 LLPILVPFILLGDIQEPGHAEGILGKP--CPKIKVECEVEEI----DQCTKPRDCPENMK 59
LLP+LV +LL Q + + K P+IKV + ++ C RDC N
Sbjct: 6 LLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDCQANNI 65
Query: 60 CCPFSRGKKCL 70
CC G C+
Sbjct: 66 CCSTYCGNVCM 76
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 26.2 bits (56), Expect = 5.9
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 12/56 (21%)
Query: 19 IQEPGHAEGILGKPCP---KIKVECEVEEIDQCTKPRDC--------PENMKC-CP 62
+Q+PG G +G CP K ++I++C P C P + +C CP
Sbjct: 327 VQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCP 382
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 26.2 bits (56), Expect = 5.9
Identities = 16/56 (28%), Positives = 25/56 (44%), Gaps = 12/56 (21%)
Query: 19 IQEPGHAEGILGKPCP---KIKVECEVEEIDQCTKPRDC--------PENMKC-CP 62
+Q+PG G +G CP K ++I++C P C P + +C CP
Sbjct: 327 VQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGDCLNNPGSYRCVCP 382
>gi|187960069 glutamate receptor, metabotropic 8 isoform b
precursor [Homo sapiens]
Length = 908
Score = 25.8 bits (55), Expect = 7.7
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 8/52 (15%)
Query: 14 ILLGDIQEPGHAEGILGKPCPKIK-------VECEVEEIDQCTKPRDCPENM 58
I+LG + P HA+G G PC ++K +E + IDQ K D N+
Sbjct: 46 IILGGLF-PVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNI 96
>gi|187960067 glutamate receptor, metabotropic 8 isoform a
precursor [Homo sapiens]
Length = 908
Score = 25.8 bits (55), Expect = 7.7
Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 8/52 (15%)
Query: 14 ILLGDIQEPGHAEGILGKPCPKIK-------VECEVEEIDQCTKPRDCPENM 58
I+LG + P HA+G G PC ++K +E + IDQ K D N+
Sbjct: 46 IILGGLF-PVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNI 96
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 25.8 bits (55), Expect = 7.7
Identities = 17/60 (28%), Positives = 27/60 (45%)
Query: 26 EGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRKVSLTLYHKEEL 85
EG L + ++ E+ + C +++ CP R K LD R V+LT + E L
Sbjct: 280 EGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPL 339
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 25.8 bits (55), Expect = 7.7
Identities = 17/60 (28%), Positives = 27/60 (45%)
Query: 26 EGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRKVSLTLYHKEEL 85
EG L + ++ E+ + C +++ CP R K LD R V+LT + E L
Sbjct: 280 EGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPL 339
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 25.8 bits (55), Expect = 7.7
Identities = 17/60 (28%), Positives = 27/60 (45%)
Query: 26 EGILGKPCPKIKVECEVEEIDQCTKPRDCPENMKCCPFSRGKKCLDFRKVSLTLYHKEEL 85
EG L + ++ E+ + C +++ CP R K LD R V+LT + E L
Sbjct: 280 EGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPL 339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.145 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,093,302
Number of Sequences: 37866
Number of extensions: 185641
Number of successful extensions: 399
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 369
Number of HSP's gapped (non-prelim): 41
length of query: 86
length of database: 18,247,518
effective HSP length: 58
effective length of query: 28
effective length of database: 16,051,290
effective search space: 449436120
effective search space used: 449436120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.