Search of human proteins with 22749421

Search of human proteins with 22749421

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
isoform 2 [Homo sapiens]
         (147 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149588599 membrane-spanning 4-domains, subfamily A, member 15...   294   2e-80
gi|22749421 membrane-spanning 4-domains, subfamily A, member 15 ...   294   2e-80
gi|8923206 membrane-spanning 4-domains, subfamily A, member 12 [...    99   1e-21
gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B ...    90   6e-19
gi|169202868 PREDICTED: similar to membrane-spanning 4-domains, ...    79   1e-15
gi|169203526 PREDICTED: similar to membrane-spanning 4-domains, ...    79   1e-15
gi|169202217 PREDICTED: similar to membrane-spanning 4-domains, ...    79   1e-15
gi|20070328 membrane-spanning 4-domains, subfamily A, member 4 i...    58   3e-09
gi|23110995 membrane-spanning 4-domains, subfamily A, member 4 i...    58   3e-09
gi|23110987 membrane-spanning 4-domains, subfamily A, member 1 [...    54   5e-08
gi|23110989 membrane-spanning 4-domains, subfamily A, member 1 [...    54   5e-08
gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A...    54   6e-08
gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A...    53   8e-08
gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A...    53   8e-08
gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A ...    52   2e-07
gi|214831008 membrane-spanning 4-domains, subfamily A, member 2 ...    51   4e-07
gi|4503677 membrane-spanning 4-domains, subfamily A, member 2 is...    51   4e-07
gi|73486649 membrane-spanning 4-domains, subfamily A, member 3 i...    51   4e-07
gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A ...    47   4e-06
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [...    47   4e-06
gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A ...    47   4e-06
gi|167466260 membrane-spanning 4-domains, subfamily A, member 10...    42   2e-04
gi|11139299 membrane-spanning 4-domains, subfamily A, member 7 i...    40   0.001
gi|46249357 membrane-spanning 4-domains, subfamily A, member 7 i...    40   0.001
gi|73486653 membrane-spanning 4-domains, subfamily A, member 3 i...    39   0.002
gi|119226217 membrane-spanning 4-domains, subfamily A, member 14...    37   0.006
gi|166795252 hypothetical protein LOC23359 [Homo sapiens]              28   2.1  
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo...    28   2.8  
gi|46249347 membrane-spanning 4-domains, subfamily A, member 7 i...    28   2.8  
gi|46249359 membrane-spanning 4-domains, subfamily A, member 7 i...    28   2.8  

>gi|149588599 membrane-spanning 4-domains, subfamily A, member 15
           isoform 1 [Homo sapiens]
          Length = 240

 Score =  294 bits (753), Expect = 2e-80
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG 60
           MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG
Sbjct: 94  MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG 153

Query: 61  TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF 120
           TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF
Sbjct: 154 TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF 213

Query: 121 SADFNIPSPAASAPPAYDNVAYAQGVV 147
           SADFNIPSPAASAPPAYDNVAYAQGVV
Sbjct: 214 SADFNIPSPAASAPPAYDNVAYAQGVV 240


>gi|22749421 membrane-spanning 4-domains, subfamily A, member 15
           isoform 2 [Homo sapiens]
          Length = 147

 Score =  294 bits (753), Expect = 2e-80
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG 60
           MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG
Sbjct: 1   MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAG 60

Query: 61  TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF 120
           TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF
Sbjct: 61  TAILLMDFGVTNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAF 120

Query: 121 SADFNIPSPAASAPPAYDNVAYAQGVV 147
           SADFNIPSPAASAPPAYDNVAYAQGVV
Sbjct: 121 SADFNIPSPAASAPPAYDNVAYAQGVV 147


>gi|8923206 membrane-spanning 4-domains, subfamily A, member 12
           [Homo sapiens]
          Length = 267

 Score = 99.4 bits (246), Expect = 1e-21
 Identities = 59/134 (44%), Positives = 81/134 (60%), Gaps = 10/134 (7%)

Query: 14  GGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDF---GV 70
           GG PFWGG  FIISGSLSV+A K  + CLV+ SLG NI+S + AF G  +LL+D    GV
Sbjct: 129 GGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCINGV 188

Query: 71  TNRDV-----DRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFN 125
             +D       +G  A L IF++LEFF A    HF  QA +   +  V+ +PN + ++  
Sbjct: 189 AGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQA-NTTTNMSVLVIPNMYESNPV 247

Query: 126 IPSPAASAPPAYDN 139
            P+ ++SAPP  +N
Sbjct: 248 TPA-SSSAPPRCNN 260


>gi|13899295 membrane-spanning 4-domains, subfamily A, member 8B
           [Homo sapiens]
          Length = 250

 Score = 90.1 bits (222), Expect = 6e-19
 Identities = 51/140 (36%), Positives = 74/140 (52%), Gaps = 14/140 (10%)

Query: 14  GGVPFWGGACFIISGSLSVAAEKN-HTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTN 72
           GG PFWGG  FIISGSLSVAAE   ++ CL+  SLG NI+S + +  G  + + D  + +
Sbjct: 105 GGFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPH 164

Query: 73  RDVDRGYL-------------AVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNA 119
                 Y               VL +F +LEF  A  + HFGCQ +  Q+S   +  PN 
Sbjct: 165 PYAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSVIYPNI 224

Query: 120 FSADFNIPSPAASAPPAYDN 139
           ++A+  I     ++PP+Y +
Sbjct: 225 YAANPVITPEPVTSPPSYSS 244


>gi|169202868 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 48/125 (38%), Positives = 68/125 (54%), Gaps = 12/125 (9%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGV---- 70
           G P WGG  +I+SGSLSV A K+ + C+V SS+  NI+S + AFAG  I++ D  +    
Sbjct: 180 GYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVT 239

Query: 71  -TNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSP 129
             ++ V  G L     F +LEF    +  HFGCQA   +    V  +P  FS  FN P+ 
Sbjct: 240 TYSKAVSGGLLP----FALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFS--FN-PAN 292

Query: 130 AASAP 134
             ++P
Sbjct: 293 TTTSP 297


>gi|169203526 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 48/125 (38%), Positives = 68/125 (54%), Gaps = 12/125 (9%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGV---- 70
           G P WGG  +I+SGSLSV A K+ + C+V SS+  NI+S + AFAG  I++ D  +    
Sbjct: 180 GYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVT 239

Query: 71  -TNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSP 129
             ++ V  G L     F +LEF    +  HFGCQA   +    V  +P  FS  FN P+ 
Sbjct: 240 TYSKAVSGGLLP----FALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFS--FN-PAN 292

Query: 130 AASAP 134
             ++P
Sbjct: 293 TTTSP 297


>gi|169202217 PREDICTED: similar to membrane-spanning 4-domains,
           subfamily A, member 8B [Homo sapiens]
          Length = 391

 Score = 79.3 bits (194), Expect = 1e-15
 Identities = 48/125 (38%), Positives = 68/125 (54%), Gaps = 12/125 (9%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGV---- 70
           G P WGG  +I+SGSLSV A K+ + C+V SS+  NI+S + AFAG  I++ D  +    
Sbjct: 180 GYPLWGGLSYIVSGSLSVWAAKDPSPCVVNSSISFNIISALFAFAGIFIIITDLSLYYVT 239

Query: 71  -TNRDVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSP 129
             ++ V  G L     F +LEF    +  HFGCQA   +    V  +P  FS  FN P+ 
Sbjct: 240 TYSKAVSGGLLP----FALLEFILTCVVSHFGCQATCCRQFENVAVIPTVFS--FN-PAN 292

Query: 130 AASAP 134
             ++P
Sbjct: 293 TTTSP 297


>gi|20070328 membrane-spanning 4-domains, subfamily A, member 4
           isoform a [Homo sapiens]
          Length = 220

 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 46/136 (33%), Positives = 64/136 (47%), Gaps = 23/136 (16%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVT--- 71
           G   WG   FIISGSLS+AA    T  LVR SLG NI S + A +G  IL+  F +    
Sbjct: 83  GYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASG--ILINTFSLAFYS 140

Query: 72  ----------NRDVDRGYLAVL-------TIFTVLEFFTAVIAMHFGCQAIHAQASAPVI 114
                     N +   G +++L        + +VLEF  AV    FGC+ +       V+
Sbjct: 141 FHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVL 200

Query: 115 FLP-NAFSADFNIPSP 129
            LP ++  A+   P+P
Sbjct: 201 ILPSHSHMAETASPTP 216


>gi|23110995 membrane-spanning 4-domains, subfamily A, member 4
           isoform b [Homo sapiens]
          Length = 239

 Score = 57.8 bits (138), Expect = 3e-09
 Identities = 46/136 (33%), Positives = 64/136 (47%), Gaps = 23/136 (16%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVT--- 71
           G   WG   FIISGSLS+AA    T  LVR SLG NI S + A +G  IL+  F +    
Sbjct: 102 GYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASG--ILINTFSLAFYS 159

Query: 72  ----------NRDVDRGYLAVL-------TIFTVLEFFTAVIAMHFGCQAIHAQASAPVI 114
                     N +   G +++L        + +VLEF  AV    FGC+ +       V+
Sbjct: 160 FHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVL 219

Query: 115 FLP-NAFSADFNIPSP 129
            LP ++  A+   P+P
Sbjct: 220 ILPSHSHMAETASPTP 235


>gi|23110987 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 53.9 bits (128), Expect = 5e-08
 Identities = 25/51 (49%), Positives = 32/51 (62%)

Query: 17  PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 67
           P WGG  +IISGSL  A EKN   CLV+  +  N LS+ AA +G  + +MD
Sbjct: 87  PLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMD 137


>gi|23110989 membrane-spanning 4-domains, subfamily A, member 1
           [Homo sapiens]
          Length = 297

 Score = 53.9 bits (128), Expect = 5e-08
 Identities = 25/51 (49%), Positives = 32/51 (62%)

Query: 17  PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 67
           P WGG  +IISGSL  A EKN   CLV+  +  N LS+ AA +G  + +MD
Sbjct: 87  PLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMD 137


>gi|239744375 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 53.5 bits (127), Expect = 6e-08
 Identities = 44/138 (31%), Positives = 60/138 (43%), Gaps = 19/138 (13%)

Query: 11  FIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD--- 67
           F+      WG   FIIS SLSVAA    T  LV  SLG NI S + A +G  I  +    
Sbjct: 102 FVYVAYTIWGSVMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTF 161

Query: 68  ----FGVTNRD-----------VDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAP 112
               +   N D           +  G   ++ + +VLEF  AV    FGC+ +    S  
Sbjct: 162 YSFRYHYCNHDQLSSNCYMTMSILMGTDGMVLLLSVLEFCIAVALSAFGCKVLCCSPSEV 221

Query: 113 VIFLP-NAFSADFNIPSP 129
           V+  P N+  A+   P+P
Sbjct: 222 VLITPSNSHMAEIASPTP 239


>gi|239755562 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 1 [Homo sapiens]
          Length = 243

 Score = 53.1 bits (126), Expect = 8e-08
 Identities = 44/138 (31%), Positives = 60/138 (43%), Gaps = 19/138 (13%)

Query: 11  FIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD--- 67
           F+      WG   FIIS SLSVAA    T  LV  SLG NI S + A +G  I  +    
Sbjct: 102 FVYVAYTIWGSVMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTF 161

Query: 68  ----FGVTNRD-----------VDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAP 112
               +   N D           +  G   ++ + +VLEF  AV    FGC+ +    S  
Sbjct: 162 YSFRYHYCNHDQLSSNCYMTMSILMGTDGMVLLLSVLEFCIAVSLSAFGCKVLCCSPSEV 221

Query: 113 VIFLP-NAFSADFNIPSP 129
           V+  P N+  A+   P+P
Sbjct: 222 VLITPSNSHMAEIASPTP 239


>gi|239750062 PREDICTED: membrane-spanning 4-domains, subfamily A,
           member 4E isoform 3 [Homo sapiens]
          Length = 243

 Score = 53.1 bits (126), Expect = 8e-08
 Identities = 44/138 (31%), Positives = 60/138 (43%), Gaps = 19/138 (13%)

Query: 11  FIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD--- 67
           F+      WG   FIIS SLSVAA    T  LV  SLG NI S + A +G  I  +    
Sbjct: 102 FVYVAYTIWGSVMFIISVSLSVAAGIRTTKGLVGGSLGKNITSSVLAISGILINAISLTF 161

Query: 68  ----FGVTNRD-----------VDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAP 112
               +   N D           +  G   ++ + +VLEF  AV    FGC+ +    S  
Sbjct: 162 YSFRYHYCNHDQLSSNCYMTMSILMGTDGMVLLLSVLEFCIAVSLSAFGCKVLCCSPSEV 221

Query: 113 VIFLP-NAFSADFNIPSP 129
           V+  P N+  A+   P+P
Sbjct: 222 VLITPSNSHMAEIASPTP 239


>gi|23238238 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 1 [Homo sapiens]
          Length = 248

 Score = 52.0 bits (123), Expect = 2e-07
 Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 35/152 (23%)

Query: 12  IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVT 71
           +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS ++A  G  IL +     
Sbjct: 83  LNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIILSVKQATL 142

Query: 72  NR-----DVDR------------------------------GYLAVLTIFTVLEFFTAVI 96
           N      ++D+                              G L+++ I T+LEF  AV+
Sbjct: 143 NPASLQCELDKNNIPTRSYVSYFYHDSLYTTDCYTAKASLAGTLSLMLICTLLEFCLAVL 202

Query: 97  AMHFGCQAIHAQASAPVIFLPNAFSADFNIPS 128
                 +  ++     V+FLP+++  +  + S
Sbjct: 203 TAVLRWKQAYSDFPGSVLFLPHSYIGNSGMSS 234


>gi|214831008 membrane-spanning 4-domains, subfamily A, member 2
           isoform 2 [Homo sapiens]
          Length = 195

 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 24/55 (43%), Positives = 34/55 (61%)

Query: 13  EGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 67
           + G PFWG   F ISG LS+ +E+ + + LVR SLG N  S +A   G  IL+++
Sbjct: 97  KAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIIN 151


>gi|4503677 membrane-spanning 4-domains, subfamily A, member 2
           isoform 1 [Homo sapiens]
          Length = 244

 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 24/55 (43%), Positives = 34/55 (61%)

Query: 13  EGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD 67
           + G PFWG   F ISG LS+ +E+ + + LVR SLG N  S +A   G  IL+++
Sbjct: 97  KAGYPFWGAIFFSISGMLSIISERRNATYLVRGSLGANTASSIAGGTGITILIIN 151


>gi|73486649 membrane-spanning 4-domains, subfamily A, member 3
           isoform a [Homo sapiens]
          Length = 214

 Score = 50.8 bits (120), Expect = 4e-07
 Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 19/133 (14%)

Query: 6   HVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILL 65
           H   F    G P WG   F  SG+LSV A    T   +++S G NI S   A  GTA L 
Sbjct: 81  HFFFFTFYTGYPIWGAVFFCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLS 140

Query: 66  MDFGVTNR-------------------DVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIH 106
           ++  V  +                    +  G +++L I T+LE    +  +   C A  
Sbjct: 141 LNIAVNIQSLRSCHSSSESPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANC 200

Query: 107 AQASAPVIFLPNA 119
             +   +   PN+
Sbjct: 201 CNSREEISSPPNS 213


>gi|23238234 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 2 [Homo sapiens]
          Length = 225

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 27/53 (50%), Positives = 32/53 (60%)

Query: 12  IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
           +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS ++A  G  IL
Sbjct: 83  LNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135


>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
           [Homo sapiens]
          Length = 200

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 20/113 (17%)

Query: 10  FFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFG 69
           F    G PFWG   FI SG+  +A ++  T  L+  S   N LS + A AG  I+L+ FG
Sbjct: 81  FIFLSGYPFWGSVLFINSGAFLIAVKRKTTETLIILSRIMNFLSALGAIAG--IILLTFG 138

Query: 70  -VTNRDVDRGY-----------------LAVLTIFTVLEFFTAVIAMHFGCQA 104
            + +++   GY                 L  L  F+++E F ++     GC +
Sbjct: 139 FILDQNYICGYSHQNSQCKAVTVLFLGILITLMTFSIIELFISLPFSILGCHS 191


>gi|23238236 membrane-spanning 4-domains, subfamily A, member 6A
           isoform 3 [Homo sapiens]
          Length = 178

 Score = 47.4 bits (111), Expect = 4e-06
 Identities = 27/53 (50%), Positives = 32/53 (60%)

Query: 12  IEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
           +    PF G   FIISGSLS+A EK  T  LV SSL  +ILS ++A  G  IL
Sbjct: 83  LNSAYPFIGPFFFIISGSLSIATEKRLTKLLVHSSLVGSILSALSALVGFIIL 135


>gi|167466260 membrane-spanning 4-domains, subfamily A, member 10
           [Homo sapiens]
          Length = 267

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 38/142 (26%), Positives = 60/142 (42%), Gaps = 25/142 (17%)

Query: 17  PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMD--------- 67
           PFWG A F+ISG L++  +    + L    L TN++S+    +G  ++  D         
Sbjct: 95  PFWGAASFLISGILAITMKTFSKTYLKMLCLMTNLISLFCVLSGLFVISKDLFLESPFES 154

Query: 68  -----FGVTNRDVDRGYLAVLTIFTVLEFF----TAVIAMHFGCQAIHAQASAPVIFLPN 118
                +  +   + R  LA+L  FTVLE F    TAV A    C    +  +     +PN
Sbjct: 155 PIWRMYPNSTVHIQRLELALL-CFTVLELFLPVPTAVTAWRGDCP---SAKNDDACLVPN 210

Query: 119 AFSADFNIPSPAASAPPAYDNV 140
                 ++       PP+Y +V
Sbjct: 211 ---TPLHLKGLPVEPPPSYQSV 229


>gi|11139299 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 22/50 (44%), Positives = 29/50 (58%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
           G PF G  CF I+GSLS+ + K  T     SSL +N +S + A AG  +L
Sbjct: 86  GYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135


>gi|46249357 membrane-spanning 4-domains, subfamily A, member 7
           isoform 1 [Homo sapiens]
          Length = 240

 Score = 39.7 bits (91), Expect = 0.001
 Identities = 22/50 (44%), Positives = 29/50 (58%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
           G PF G  CF I+GSLS+ + K  T     SSL +N +S + A AG  +L
Sbjct: 86  GYPFLGALCFGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 135


>gi|73486653 membrane-spanning 4-domains, subfamily A, member 3
           isoform b [Homo sapiens]
          Length = 168

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 19/115 (16%)

Query: 24  FIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTNR---------- 73
           F  SG+LSV A    T   +++S G NI S   A  GTA L ++  V  +          
Sbjct: 53  FCSSGTLSVVAGIKPTRTWIQNSFGMNIASATIALVGTAFLSLNIAVNIQSLRSCHSSSE 112

Query: 74  ---------DVDRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPVIFLPNA 119
                     +  G +++L I T+LE    +  +   C A    +   +   PN+
Sbjct: 113 SPDLCNYMGSISNGMVSLLLILTLLELCVTISTIAMWCNANCCNSREEISSPPNS 167


>gi|119226217 membrane-spanning 4-domains, subfamily A, member 14
           isoform 1 [Homo sapiens]
          Length = 679

 Score = 37.0 bits (84), Expect = 0.006
 Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 2/54 (3%)

Query: 15  GVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDF 68
           G PFWG   FI++G L+V  +K  +  L +   G N++S + A  G    ++ +
Sbjct: 81  GYPFWGALIFILTGYLTVTDKK--SKLLGQGVTGMNVISSLVAITGITFTILSY 132


>gi|166795252 hypothetical protein LOC23359 [Homo sapiens]
          Length = 539

 Score = 28.5 bits (62), Expect = 2.1
 Identities = 14/56 (25%), Positives = 27/56 (48%)

Query: 17  PFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAILLMDFGVTN 72
           PFW G   ++SG + V + K   S ++   +  + + VM   AG+ +   +  + N
Sbjct: 67  PFWAGFSVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQLVN 122


>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
            sapiens]
          Length = 1724

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 15/35 (42%), Positives = 19/35 (54%)

Query: 101  GCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPP 135
            G  + H  AS+P  F P+A S   N+  P ASA P
Sbjct: 1450 GFGSYHPSASSPFHFQPSAASLTANLRLPMASALP 1484


>gi|46249347 membrane-spanning 4-domains, subfamily A, member 7
          isoform 2 [Homo sapiens]
          Length = 195

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 17/41 (41%), Positives = 24/41 (58%)

Query: 24 FIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
          F I+GSLS+ + K  T     SSL +N +S + A AG  +L
Sbjct: 50 FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 90


>gi|46249359 membrane-spanning 4-domains, subfamily A, member 7
          isoform 2 [Homo sapiens]
          Length = 195

 Score = 28.1 bits (61), Expect = 2.8
 Identities = 17/41 (41%), Positives = 24/41 (58%)

Query: 24 FIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGTAIL 64
          F I+GSLS+ + K  T     SSL +N +S + A AG  +L
Sbjct: 50 FGITGSLSIISGKQSTKPFDLSSLTSNAVSSVTAGAGLFLL 90


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,006,769
Number of Sequences: 37866
Number of extensions: 179571
Number of successful extensions: 716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 665
Number of HSP's gapped (non-prelim): 40
length of query: 147
length of database: 18,247,518
effective HSP length: 93
effective length of query: 54
effective length of database: 14,725,980
effective search space: 795202920
effective search space used: 795202920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.