BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|226442779 jumonji domain containing 1A [Homo sapiens] (1321 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|226442779 jumonji domain containing 1A [Homo sapiens] 2704 0.0 gi|20357522 jumonji domain containing 1A [Homo sapiens] 2704 0.0 gi|38372909 jumonji domain containing 1B [Homo sapiens] 1041 0.0 gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] 767 0.0 gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] 760 0.0 gi|22547204 hairless protein isoform a [Homo sapiens] 228 2e-59 gi|22547207 hairless protein isoform b [Homo sapiens] 177 8e-44 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 41 0.009 gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] 39 0.043 gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens] 37 0.16 gi|145199237 transcription elongation factor B polypeptide 3 bin... 37 0.16 gi|239788849 jumonji domain containing 4 isoform 2 [Homo sapiens] 36 0.21 gi|239788847 jumonji domain containing 4 isoform 1 [Homo sapiens] 36 0.21 gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 36 0.21 gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 36 0.21 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 36 0.21 gi|197245440 hypothetical protein LOC23285 [Homo sapiens] 36 0.28 gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 35 0.36 gi|225543474 myotubularin related protein 7 [Homo sapiens] 35 0.48 gi|118026921 asparagine-linked glycosylation 9 protein isoform a... 35 0.48 gi|118026935 asparagine-linked glycosylation 9 protein isoform d... 35 0.48 gi|118026937 asparagine-linked glycosylation 9 protein isoform c... 35 0.48 gi|118026933 asparagine-linked glycosylation 9 protein isoform b... 35 0.48 gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom... 35 0.62 gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ... 35 0.62 gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 34 0.81 gi|189011568 adenomatous polyposis coli [Homo sapiens] 34 1.1 gi|189011566 adenomatous polyposis coli [Homo sapiens] 34 1.1 gi|53759122 adenomatous polyposis coli [Homo sapiens] 34 1.1 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 33 1.4 >gi|226442779 jumonji domain containing 1A [Homo sapiens] Length = 1321 Score = 2704 bits (7010), Expect = 0.0 Identities = 1321/1321 (100%), Positives = 1321/1321 (100%) Query: 1 MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD 60 MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD Sbjct: 1 MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD 60 Query: 61 LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL 120 LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL Sbjct: 61 LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL 120 Query: 121 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE 180 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE Sbjct: 121 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE 180 Query: 181 SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH 240 SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH Sbjct: 181 SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH 240 Query: 241 VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI 300 VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI Sbjct: 241 VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI 300 Query: 301 LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK 360 LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK Sbjct: 301 LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK 360 Query: 361 PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT 420 PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT Sbjct: 361 PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT 420 Query: 421 KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR 480 KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR Sbjct: 421 KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR 480 Query: 481 SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV 540 SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV Sbjct: 481 SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV 540 Query: 541 AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI 600 AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI Sbjct: 541 AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI 600 Query: 601 GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE 660 GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE Sbjct: 601 GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE 660 Query: 661 MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL 720 MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL Sbjct: 661 MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL 720 Query: 721 MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP 780 MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP Sbjct: 721 MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP 780 Query: 781 TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ 840 TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ Sbjct: 781 TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ 840 Query: 841 PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL 900 PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL Sbjct: 841 PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL 900 Query: 901 KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK 960 KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK Sbjct: 901 KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK 960 Query: 961 SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV 1020 SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV Sbjct: 961 SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV 1020 Query: 1021 GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK 1080 GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK Sbjct: 1021 GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK 1080 Query: 1081 LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC 1140 LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC Sbjct: 1081 LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC 1140 Query: 1141 EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN 1200 EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN Sbjct: 1141 EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN 1200 Query: 1201 PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV 1260 PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV Sbjct: 1201 PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV 1260 Query: 1261 AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK 1320 AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK Sbjct: 1261 AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK 1320 Query: 1321 P 1321 P Sbjct: 1321 P 1321 >gi|20357522 jumonji domain containing 1A [Homo sapiens] Length = 1321 Score = 2704 bits (7010), Expect = 0.0 Identities = 1321/1321 (100%), Positives = 1321/1321 (100%) Query: 1 MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD 60 MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD Sbjct: 1 MVLTLGESWPVLVGRRFLSLSAADGSDGSHDSWDVERVAEWPWLSGTIRAVSHTDVTKKD 60 Query: 61 LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL 120 LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL Sbjct: 61 LKVCVEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISERIVQWPAITYKPLL 120 Query: 121 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE 180 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE Sbjct: 121 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRLSLTDNQIVSKEFQALIVKHLDE 180 Query: 181 SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH 240 SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH Sbjct: 181 SHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIH 240 Query: 241 VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI 300 VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI Sbjct: 241 VEVVHDNLVTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEI 300 Query: 301 LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK 360 LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK Sbjct: 301 LLGCTAATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTK 360 Query: 361 PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT 420 PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT Sbjct: 361 PDVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPT 420 Query: 421 KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR 480 KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR Sbjct: 421 KASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACR 480 Query: 481 SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV 540 SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV Sbjct: 481 SQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQSGEAFVQDDSCVNIV 540 Query: 541 AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI 600 AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI Sbjct: 541 AQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRLQFNKHGVLRVEGFLTPNKYDNEAI 600 Query: 601 GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE 660 GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE Sbjct: 601 GLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISEKEAMSTIEPHRQVAWKRAVKGVRE 660 Query: 661 MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL 720 MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL Sbjct: 661 MCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQQGAAYKTFSWLKCVKSQIHEPENL 720 Query: 721 MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP 780 MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP Sbjct: 721 MPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNRQFKLFSKPASKEDLKQTSLAGEKP 780 Query: 781 TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ 840 TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ Sbjct: 781 TLGAVLQQNPSVLEPAAVGGEAASKPAGSMKPACPASTSPLNWLADLTSGNVNKENKEKQ 840 Query: 841 PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL 900 PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL Sbjct: 841 PTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTILTPVSNNNSGFLRNLLNSSTGKTENGL 900 Query: 901 KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK 960 KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK Sbjct: 901 KNTPKILDDIFASLVQNKTTSDLSKRPQGLTIKPSILGFDTPHYWLCDNRLLCLQDPNNK 960 Query: 961 SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV 1020 SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV Sbjct: 961 SNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATV 1020 Query: 1021 GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK 1080 GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK Sbjct: 1021 GDFWDGFEDVPNRLKNEKEPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGK 1080 Query: 1081 LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC 1140 LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC Sbjct: 1081 LNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQC 1140 Query: 1141 EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN 1200 EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN Sbjct: 1141 EQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQEN 1200 Query: 1201 PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV 1260 PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV Sbjct: 1201 PADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKV 1260 Query: 1261 AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK 1320 AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK Sbjct: 1261 AEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK 1320 Query: 1321 P 1321 P Sbjct: 1321 P 1321 >gi|38372909 jumonji domain containing 1B [Homo sapiens] Length = 1761 Score = 1041 bits (2692), Expect = 0.0 Identities = 527/882 (59%), Positives = 636/882 (72%), Gaps = 72/882 (8%) Query: 511 KSVLTDPAKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKEQ-QKDSPVFCR 569 +SVL D +K+KKL+QSGE F+QD SC+N+ L KCRECRL+ RK KEQ Q DS V CR Sbjct: 879 QSVLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACR 938 Query: 570 FFHFRRLQFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHF 629 FFHFRRL F + GVLRVEGFL+P + D +A+ LW+P + GIDL+T+KYILAN+GD F Sbjct: 939 FFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMNLWIPSSSLAEGIDLETSKYILANVGDQF 998 Query: 630 CQMVISEKEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYR 689 CQ+V+SEKEAM +EPH++VAWKRAV+GVREMCDVC+TT+FN+HWVC +CGFGVC+DCYR Sbjct: 999 CQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYR 1058 Query: 690 MK----RKNCQQGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKW 745 ++ R ++ + FSWLKC K Q HEPENLMPTQIIPG ALY++GD+VH+ R KW Sbjct: 1059 LRKSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKW 1118 Query: 746 GIKANCPCSNRQFKLFSKPASKEDLKQ------TSLAGEKPTLGA------VLQQNPSVL 793 GIKANCPC +RQ K +PA + Q ++ +G + T V P + Sbjct: 1119 GIKANCPCISRQNKSVLRPAVTNGMSQLPSINPSASSGNETTFSGGGGPAPVTTPEPDHV 1178 Query: 794 -----------EPAAVGGEAASKPA--GSMKPACPASTSP---LNWLADLTSGNVNKENK 837 EP A++ + +++P CP + P L+WLADL + +E K Sbjct: 1179 PKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETK 1238 Query: 838 EKQPTMPILKNEIKCLPPLPPLSKSSTVL----HTFNSTILTPVSNNN---SGFLRNLLN 890 E +L E L + ++ V FNS +L P ++NN LR+LL+ Sbjct: 1239 EAGSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLH 1298 Query: 891 SSTGK------------------TENGLK---NTPKILDDIFASLVQNKTTSDLSKRPQG 929 S GK + G+K + P LD I AS+V+NK TSD SKR Sbjct: 1299 SGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKASLPNFLDHIIASVVENKKTSDASKRACN 1358 Query: 930 LT-----IKPSILGFD-----TPHYWLCDNRLLCLQDPNNKSNWNVFRECWKQGQPVMVS 979 LT +K ++G + T H WLCD RLLCL DP+NK+NW +FRECWKQGQPV+VS Sbjct: 1359 LTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVS 1418 Query: 980 GVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEK- 1038 GVH KL SELWKPE+F +EFG+Q+VDLVNCR II+ V DFWDGFE + RL++E Sbjct: 1419 GVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDG 1478 Query: 1039 EPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGP 1098 +PMVLKLKDWPPGEDFRDMMP+RF+DLM N+PLPEYT+RDG+LNLASRLP+YFVRPDLGP Sbjct: 1479 QPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGP 1538 Query: 1099 KMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLKTIQDGDSDEL 1158 KMYNAYGLIT EDR+ GTTNLHLDVSDA NVMVYVGIP G+ +EEVLKTI +GD+DE+ Sbjct: 1539 KMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEV 1598 Query: 1159 TIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSL 1218 T +R +GKEKPGALWHIYAAKD EKIRE L+KV EEQGQENP DHDPIHDQSWYLD++L Sbjct: 1599 TKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTL 1658 Query: 1219 RKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQ 1278 RKRL++EYGVQGWAIVQFLGD VFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCF LTQ Sbjct: 1659 RKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQ 1718 Query: 1279 EFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASESSFGK 1320 EFR+LS THTNHEDKLQVKN+IYHAVKDAV LKA ES + Sbjct: 1719 EFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLKAHESKLAR 1760 Score = 115 bits (288), Expect = 3e-25 Identities = 88/298 (29%), Positives = 140/298 (46%), Gaps = 34/298 (11%) Query: 13 VGRRFLSLSAADGSDGSHDSWDVERVAEWP--------WLSGTIRAVSHTDVTKKDLKVC 64 VG+R L L A + S + + P W +GT+RA+S +DL + Sbjct: 9 VGKRLLLLFADTAASASASAPAAAAASGDPGPALRTRAWRAGTVRAMS--GAVPQDLAIF 66 Query: 65 VEFDGESWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISE----RIVQWPAITYKPLL 120 VEFDG +W++ W++V++ L+E +LV A R+ P + + I QWPA+T+ PL+ Sbjct: 67 VEFDGCNWKQHSWVKVHAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLV 126 Query: 121 DKAGLGSITSVRFLGDQQRVFLSKDLLKPIQDVNSLRL----------SLTDNQIVSKEF 170 DK GLGS+ V +L D++ FLS D N L L L ++ + + Sbjct: 127 DKLGLGSVVPVEYLLDRELRFLS--------DANGLHLFQMGTDSQNQILLEHAALRETV 178 Query: 171 QALIVKHLDESHLLKGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPA 230 ALI + +G ++ G VKIY + W V + + ++ ++V+ E Sbjct: 179 NALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGE 238 Query: 231 LKIVDPSLIHVEVVHDNLVTCGNSARIGAVK-RKSSENNGTLVSKQAKSCSEASPSMC 287 +K VDP LIHV ++ DN + AVK K + ++ K + AS S C Sbjct: 239 IKSVDPRLIHV-MLMDNSTPQSEGGTLKAVKSSKGKKKRESIEGKDGRRRKSASDSGC 295 Score = 35.0 bits (79), Expect = 0.48 Identities = 44/173 (25%), Positives = 67/173 (38%), Gaps = 24/173 (13%) Query: 318 STPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALR---TKPDVCKAGLLSKSSQ 374 S+ Q A +L + C Q+LP S+ T SE+L + D K L S SS Sbjct: 510 SSAQEAQKDTDLSKNLFFQCMSQTLPT--SNYFTTVSESLADDSSSRDSFKQSLESLSSG 567 Query: 375 IGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPTKASSKAELEIANPP 434 + G + T+ K ++ ++ D++ ES+P P+ L + E PP Sbjct: 568 LCKGRSVLGTDTKPG-SKAGSSVDRKVPAESMPTLTPAFPRSLLNARTPENHENLFLQPP 626 Query: 435 ELQKH------------LEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPS 475 +L + +EH+P S S A S S KV PS Sbjct: 627 KLSREEPSNPFLAFVEKVEHSPFSSFASQAS------GSSSSATTVTSKVAPS 673 >gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens] Length = 2303 Score = 767 bits (1981), Expect = 0.0 Identities = 426/1020 (41%), Positives = 611/1020 (59%), Gaps = 106/1020 (10%) Query: 369 LSKSSQIGTGDLKILTEP-------KGSCTQPKTNTDQENRLESVPQALTGLPKEC---L 418 ++K++ +G G ++P K T+ N++E+ +++ + K C L Sbjct: 1308 INKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNL 1367 Query: 419 PTKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGK-------- 470 SS + + + + K+++ D N + K S S + S + Sbjct: 1368 IASTSSDIQNSVDSKIIVDKYVK-----DDKVNRRKAKRTYESGSESGDSDESESKSEQR 1422 Query: 471 -KVEPSALACRSQN---LKESSVKVD-------NESCCSRSNNKIQ---NAPSRKSVLTD 516 K +P + QN ++ ++ D + S RS K+Q N +SVL D Sbjct: 1423 TKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKD 1482 Query: 517 PAKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRL 576 K+KKL+Q+GE+F+QDDSC I L KCRECRL +K E+ SPVFCRF++FRRL Sbjct: 1483 WRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKG-EEPAHSPVFCRFYYFRRL 1541 Query: 577 QFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISE 636 F+K+GV+R++GF +P++YD+EA+ LW +D++T+KYIL IGD FCQ+V SE Sbjct: 1542 SFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSE 1601 Query: 637 KEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQ 696 K A+S ++ ++AWKRAV+GVREMCD C+ T+FN+HWVC +CGF VC+DCY+ K + Sbjct: 1602 KTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSS 1661 Query: 697 QGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNR 756 + + ++W+KCVK Q H+ ++LMPTQIIPG L D+ D +H++R K+GIK++C C+N Sbjct: 1662 RDK--ELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTN- 1718 Query: 757 QFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAV--GGEAASKPAGS-MKPA 813 KQ G PT+ V Q P + GG + G+ K Sbjct: 1719 --------------KQNLQVGNFPTMNGVSQSQQQNTPPKSEKNGGSSPESDVGTDNKLT 1764 Query: 814 CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNSTI 873 P S SPL+WLADL +E KE + L+N+IK + ++ ++ Sbjct: 1765 PPESQSPLHWLADLAEQKAREEKKENKELT--LENQIK-----EEREQDNSESPNGRTSP 1817 Query: 874 LTPVSNNNSGFLRNLLNSSTGK-----TENGL----------------KNTPKILDDIFA 912 L +N LR+LL ++ GK T+ G+ + P ILDDI A Sbjct: 1818 LVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIA 1877 Query: 913 SLVQNKT----TSDLSKRPQGLTIKP-----------SILGFDTPHYWLCDNRLLCLQDP 957 S+V+NK TS ++ +P+ L +P + L D PH W+C+ +L L+D Sbjct: 1878 SVVENKIPPSKTSKINVKPE-LKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDY 1936 Query: 958 NNKSNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEIITG 1017 N SNW +F+ECWKQGQP +VSGVH K+N LWK ES +FG+ + DL+NC+ + II+ Sbjct: 1937 KNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCK-DSIISN 1995 Query: 1018 ATVGDFWDGFEDVPNRLKNEK-EPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPEYTR 1076 A V +FWDGFE+V R KN+ E +VLKLKDWP GEDF+ MMP+R++DL+ ++PLPEY Sbjct: 1996 ANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCN 2055 Query: 1077 RDGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYVGIP 1136 +GK NLAS LP +FVRPDLGP++ +AYG++ +D GTTNLH++VSD N++VYVGI Sbjct: 2056 PEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIA 2115 Query: 1137 KGQ-CEQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKVSEE 1195 KG + +LK ++ D D++ KR + E PGALWHIYA KD +KIREFL+K+S+E Sbjct: 2116 KGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKE 2175 Query: 1196 QGQENPADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVHNLY 1255 QG E +HDPI DQSWY+++ LR+RL +EYGV+ ++QFLGD + +PAGA HQV N + Sbjct: 2176 QGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFH 2235 Query: 1256 SCIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLKASE 1315 SCI+V EDFVSPEH+ F LTQE R L + N++DKLQVKN++YHAVK+ V LK E Sbjct: 2236 SCIQVTEDFVSPEHLVESFHLTQELRLLKE-EINYDDKLQVKNILYHAVKEMVRALKIHE 2294 >gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens] Length = 2540 Score = 760 bits (1963), Expect = 0.0 Identities = 420/1023 (41%), Positives = 611/1023 (59%), Gaps = 94/1023 (9%) Query: 369 LSKSSQIGTGDLKILTEP-------KGSCTQPKTNTDQENRLESVPQALTGLPKEC---L 418 ++K++ +G G ++P K T+ N++E+ +++ + K C L Sbjct: 1527 INKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNL 1586 Query: 419 PTKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGK-------- 470 SS + + + + K+++ D N + K S S + S + Sbjct: 1587 IASTSSDIQNSVDSKIIVDKYVK-----DDKVNRRKAKRTYESGSESGDSDESESKSEQR 1641 Query: 471 -KVEPSALACRSQN---LKESSVKVD-------NESCCSRSNNKIQ---NAPSRKSVLTD 516 K +P + QN ++ ++ D + S RS K+Q N +SVL D Sbjct: 1642 TKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKD 1701 Query: 517 PAKLKKLQQSGEAFVQDDSCVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRRL 576 K+KKL+Q+GE+F+QDDSC I L KCRECRL +K E+ SPVFCRF++FRRL Sbjct: 1702 WRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKG-EEPAHSPVFCRFYYFRRL 1760 Query: 577 QFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVISE 636 F+K+GV+R++GF +P++YD+EA+ LW +D++T+KYIL IGD FCQ+V SE Sbjct: 1761 SFSKNGVVRIDGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSE 1820 Query: 637 KEAMSTIEPHRQVAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKNCQ 696 K A+S ++ ++AWKRAV+GVREMCD C+ T+FN+HWVC +CGF VC+DCY+ K + Sbjct: 1821 KTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSS 1880 Query: 697 QGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPCSNR 756 + + ++W+KCVK Q H+ ++LMPTQIIPG L D+ D +H++R K+GIK++C C+N+ Sbjct: 1881 RDK--ELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNK 1938 Query: 757 QFKLFSKPASKEDLKQT--SLAGEKPTLGAVLQQNPSVLEPAAVGGEAASKPAGSM---- 810 Q + + Q ++ + + ++ P S P + Sbjct: 1939 QNLQVGNFPTMNGVSQVLQNVLNHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDN 1998 Query: 811 KPACPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFN 870 K P S SPL+WLADL +E KE + L+N+IK + ++ Sbjct: 1999 KLTPPESQSPLHWLADLAEQKAREEKKENKELT--LENQIK-----EEREQDNSESPNGR 2051 Query: 871 STILTPVSNNNSGFLRNLLNSSTGK-----TENGL----------------KNTPKILDD 909 ++ L +N LR+LL ++ GK T+ G+ + P ILDD Sbjct: 2052 TSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDD 2111 Query: 910 IFASLVQNKT----TSDLSKRPQGLTIKP-----------SILGFDTPHYWLCDNRLLCL 954 I AS+V+NK TS ++ +P+ L +P + L D PH W+C+ +L L Sbjct: 2112 IIASVVENKIPPSKTSKINVKPE-LKEEPEESIISAVDENNKLYSDIPHSWICEKHILWL 2170 Query: 955 QDPNNKSNWNVFRECWKQGQPVMVSGVHHKLNSELWKPESFRKEFGEQEVDLVNCRTNEI 1014 +D N SNW +F+ECWKQGQP +VSGVH K+N LWK ES +FG+ + DL+NC+ + I Sbjct: 2171 KDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCK-DSI 2229 Query: 1015 ITGATVGDFWDGFEDVPNRLKNEK-EPMVLKLKDWPPGEDFRDMMPSRFDDLMANIPLPE 1073 I+ A V +FWDGFE+V R KN+ E +VLKLKDWP GEDF+ MMP+R++DL+ ++PLPE Sbjct: 2230 ISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPE 2289 Query: 1074 YTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITPEDRKYGTTNLHLDVSDAANVMVYV 1133 Y +GK NLAS LP +FVRPDLGP++ +AYG++ +D GTTNLH++VSD N++VYV Sbjct: 2290 YCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYV 2349 Query: 1134 GIPKGQ-CEQEEEVLKTIQDGDSDELTIKRFIEGKEKPGALWHIYAAKDTEKIREFLKKV 1192 GI KG + +LK ++ D D++ KR + E PGALWHIYA KD +KIREFL+K+ Sbjct: 2350 GIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKI 2409 Query: 1193 SEEQGQENPADHDPIHDQSWYLDRSLRKRLHQEYGVQGWAIVQFLGDVVFIPAGAPHQVH 1252 S+EQG E +HDPI DQSWY+++ LR+RL +EYGV+ ++QFLGD + +PAGA HQV Sbjct: 2410 SKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQ 2469 Query: 1253 NLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQTHTNHEDKLQVKNVIYHAVKDAVAMLK 1312 N +SCI+V EDFVSPEH+ F LTQE R L + N++DKLQVKN++YHAVK+ V LK Sbjct: 2470 NFHSCIQVTEDFVSPEHLVESFHLTQELRLLKE-EINYDDKLQVKNILYHAVKEMVRALK 2528 Query: 1313 ASE 1315 E Sbjct: 2529 IHE 2531 Score = 146 bits (368), Expect = 1e-34 Identities = 89/264 (33%), Positives = 149/264 (56%), Gaps = 12/264 (4%) Query: 12 LVGRRFLSLSAADGSDGSHDSWDVERVAEW-PWLSGTIRAVSHTDVTKKDLKVCVEFDGE 70 LVG+RFL ++ D + + W+ R W W +G IRAVSH D DL V VEFD Sbjct: 9 LVGKRFLCVAVGD--EARSERWESGR--GWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDL 64 Query: 71 SWRKRRWIEVYSLLRRAFLVEHNLVLAERKSPEISE----RIVQWPAITYKPLLDKAGLG 126 W KR W++VY FLVE++L+ A+R P ++ + +QWPA+T+KPL+++ Sbjct: 65 EWDKREWVKVYEDFS-TFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPS 123 Query: 127 SITSVRFLGDQQRVFLSKD-LLKPIQD-VNSLRLSLTDNQIVSKEFQALIVKHLDESHLL 184 S+T+V FL D+Q FL++D +P QD ++SL L DN + +E + + + + + Sbjct: 124 SVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEEVKVWVKEQKVQEIFM 183 Query: 185 KGDKNLVGSEVKIYSLDPSTQWFSATVINGNPASKTLQVNCEEIPALKIVDPSLIHVEVV 244 +G +L G V++Y D +TQWF+ + + + ++T+ V +++ + VDPS++ + + Sbjct: 184 QGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFL 243 Query: 245 HDNLVTCGNSARIGAVKRKSSENN 268 D + + IG R+ S N Sbjct: 244 DDVVHSLLKGENIGITSRRRSRAN 267 >gi|22547204 hairless protein isoform a [Homo sapiens] Length = 1189 Score = 228 bits (582), Expect = 2e-59 Identities = 204/763 (26%), Positives = 332/763 (43%), Gaps = 100/763 (13%) Query: 521 KKLQQSGEAFVQDDS-----CVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRR 575 +K Q G+A +QD C+ + A+L +C+ C + + C RR Sbjct: 467 QKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCA-------QAAGEGGGHACHSQQVRR 519 Query: 576 LQFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVIS 635 G L+ E N E G P ++ G+ AK++L+ +GD C+++ Sbjct: 520 SPLG--GELQQEEDTATNSSSEEGPGSG-PDSRLSTGL----AKHLLSGLGDRLCRLLRR 572 Query: 636 EKEAMSTIEPHRQ-VAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKN 694 E+EA++ + Q A G+ C C +FN HW CPRC +CV C R+ Sbjct: 573 EREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTG 632 Query: 695 -CQQGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPC 753 ++ A ++ S +C + H +LM TQ + +AL ++ +H V K+ I+ +CPC Sbjct: 633 RAREKAGFQEQSAEECTQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPC 692 Query: 754 -SNRQFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAVGGEAASKPAGSMKP 812 ++ + +++ Q + +P+ + S+ E E ++ P Sbjct: 693 QADARVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGP 752 Query: 813 A-CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNS 871 CP+ L +L + K + + + P P L + + +S Sbjct: 753 LPCPS-------LCELLASTAVKLCLGHE------RIHMAFAPVTPALPSDDRITNILDS 799 Query: 872 TILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTTSDLSKRPQGLT 931 I V R + + G GL+ P + ++ GL Sbjct: 800 IIAQVVE-------RKIQEKALGP---GLRAGPGL------------------RKGLGLP 831 Query: 932 IKPSILGFDTPHYWLCDNRLLCLQDPNN--KSNWNVFRECWKQGQPVMVSGVHHKLNSEL 989 + P P LL LQ+P + +++F+E W+QGQPV+VSG+ L L Sbjct: 832 LSPVRPRLPPP------GALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNL 885 Query: 990 WKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEPMVLKLKDWP 1049 W E+ G+ + G+T FW+GF R K++ E VL L Sbjct: 886 WGTEALGALGGQVQALSPLGPPQPSSLGSTT--FWEGFSWPELRPKSD-EGSVLLLHRAL 942 Query: 1050 PGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITP 1109 ED SR ++L A++PLPEY GKLNLAS LP L P+++ AYG ++P Sbjct: 943 GDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYG-VSP 996 Query: 1110 EDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLKTIQDGDSDELTIKRFIEGKEK 1169 GT NL ++V+D +++V+ P + ++ + DG EG Sbjct: 997 HRGHLGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDG-----------EGLWS 1045 Query: 1170 PGA----LWHIYAAKDTEKIREFLKKVSEEQGQENPADHDPIHDQSWYLDRSLRKRLHQE 1225 PG+ +WH++ A+D ++IR FL+ V +P S YLD LR+RL +E Sbjct: 1046 PGSQVSTVWHVFRAQDAQRIRRFLQMVCPA----GAGALEPGAPGSCYLDAGLRRRLREE 1101 Query: 1226 YGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPE 1268 +GV W ++Q G+ V +PAGAPHQV L S + V + F+SPE Sbjct: 1102 WGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPE 1144 >gi|22547207 hairless protein isoform b [Homo sapiens] Length = 1134 Score = 177 bits (448), Expect = 8e-44 Identities = 182/736 (24%), Positives = 303/736 (41%), Gaps = 102/736 (13%) Query: 521 KKLQQSGEAFVQDDS-----CVNIVAQLPKCRECRLDSLRKDKEQQKDSPVFCRFFHFRR 575 +K Q G+A +QD C+ + A+L +C+ C + + C RR Sbjct: 467 QKGPQDGQASLQDPGLQDIPCLALPAKLAQCQSCA-------QAAGEGGGHACHSQQVRR 519 Query: 576 LQFNKHGVLRVEGFLTPNKYDNEAIGLWLPLTKNVVGIDLDTAKYILANIGDHFCQMVIS 635 G L+ E N E G P ++ G+ AK++L+ +GD C+++ Sbjct: 520 SPLG--GELQQEEDTATNSSSEEGPGSG-PDSRLSTGL----AKHLLSGLGDRLCRLLRR 572 Query: 636 EKEAMSTIEPHRQ-VAWKRAVKGVREMCDVCDTTIFNLHWVCPRCGFGVCVDCYRMKRKN 694 E+EA++ + Q A G+ C C +FN HW CPRC +CV C R+ Sbjct: 573 EREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAGTG 632 Query: 695 -CQQGAAYKTFSWLKCVKSQIHEPENLMPTQIIPGKALYDVGDIVHSVRAKWGIKANCPC 753 ++ A ++ S +C + H +LM TQ + +AL ++ +H V K+ I+ +CPC Sbjct: 633 RAREKAGFQEQSAEECTQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPC 692 Query: 754 -SNRQFKLFSKPASKEDLKQTSLAGEKPTLGAVLQQNPSVLEPAAVGGEAASKPAGSMKP 812 ++ + +++ Q + +P+ + S+ E E ++ P Sbjct: 693 QADARVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGP 752 Query: 813 A-CPASTSPLNWLADLTSGNVNKENKEKQPTMPILKNEIKCLPPLPPLSKSSTVLHTFNS 871 CP+ L +L + K + + + P P L + + +S Sbjct: 753 LPCPS-------LCELLASTAVKLCLGHE------RIHMAFAPVTPALPSDDRITNILDS 799 Query: 872 TILTPVSNNNSGFLRNLLNSSTGKTENGLKNTPKILDDIFASLVQNKTTSDLSKRPQGLT 931 I V R + + G GL+ P + ++ GL Sbjct: 800 IIAQVVE-------RKIQEKALGP---GLRAGPGL------------------RKGLGLP 831 Query: 932 IKPSILGFDTPHYWLCDNRLLCLQDPNN--KSNWNVFRECWKQGQPVMVSGVHHKLNSEL 989 + P P LL LQ+P + +++F+E W+QGQPV+VSG+ L L Sbjct: 832 LSPVRPRLPPP------GALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNL 885 Query: 990 WKPESFRKEFGEQEVDLVNCRTNEIITGATVGDFWDGFEDVPNRLKNEKEPMVLKLKDWP 1049 W E+ G+ + G+T FW+GF R K++ E VL L Sbjct: 886 WGTEALGALGGQVQALSPLGPPQPSSLGSTT--FWEGFSWPELRPKSD-EGSVLLLHRAL 942 Query: 1050 PGEDFRDMMPSRFDDLMANIPLPEYTRRDGKLNLASRLPNYFVRPDLGPKMYNAYGLITP 1109 ED SR ++L A++PLPEY GKLNLAS LP L P+++ AYG ++P Sbjct: 943 GDED-----TSRVENLAASLPLPEYCALHGKLNLASYLPPGLALRPLEPQLWAAYG-VSP 996 Query: 1110 EDRKYGTTNLHLDVSDAANVMVYVGIPKGQCEQEEEVLKTIQDGDSDELTIKRFIEGKEK 1169 GT NL ++V+D +++V+ P + ++ + DG EG Sbjct: 997 HRGHLGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDG-----------EGLWS 1045 Query: 1170 PGA----LWHIYAAKDTEKIREFLKKVSEEQGQENPADH------DPIHDQSWYLDRSLR 1219 PG+ +WH++ A+D ++IR FL+ V + H + Q + SL Sbjct: 1046 PGSQVSTVWHVFRAQDAQRIRRFLQMVQGLVSTVSVTQHFLSPETSALSAQLCHQGPSLP 1105 Query: 1220 KRLHQEYGVQGWAIVQ 1235 H Y WA+ Q Sbjct: 1106 PDCHLLYAQMDWAVFQ 1121 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 40.8 bits (94), Expect = 0.009 Identities = 66/266 (24%), Positives = 104/266 (39%), Gaps = 37/266 (13%) Query: 249 VTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEILLGCT--- 305 V G R G++ S + N V+ Q +SC E+SP P+ + G + Sbjct: 844 VKSGTPPRQGSIT--SPQANEQSVTPQRRSCFESSPDPELKSRTPS---RHSCSGSSPPR 898 Query: 306 --AATPPSKDPRQQSTPQ----AANSP---PNLGAKIPQGCHKQS-----LPEEISSCLN 351 ++TPP + P + S+PQ A SP + G+ P S +S C N Sbjct: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958 Query: 352 TKSEAL-------RTKPDV-CKAGLLSKSSQIGT----GDLKILTEPKGSCTQPKTNTDQ 399 +S L + PD K + S G+ +K T P S + K+ Q Sbjct: 959 VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQ 1018 Query: 400 ENRLESVPQALTGLPKECLPTKASSKAELEIANPPELQKHLEHAPSPSDVS--NAPEVKA 457 E +S+ Q+ G C K+S+ LQ + SP S ++PEV+ Sbjct: 1019 EKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQ 1078 Query: 458 GVNSDSPNNCSGKKVEPSALACRSQN 483 +S+SP+ S + P RS + Sbjct: 1079 S-HSESPSLQSKSQTSPKGGRSRSSS 1103 Score = 32.7 bits (73), Expect = 2.4 Identities = 29/96 (30%), Positives = 40/96 (41%), Gaps = 11/96 (11%) Query: 259 AVKRKSSENNGTLVSKQAKSCSEASPS-----MCPVQSVPTTVFKEILLGCT---AATPP 310 A K+ SS K+ KS + SPS P PT + E G A TP Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL 386 Query: 311 SKDP---RQQSTPQAANSPPNLGAKIPQGCHKQSLP 343 S++P +++P SPP K+PQ +S P Sbjct: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSP 422 >gi|46255064 synaptotagmin-like 2 isoform d [Homo sapiens] Length = 1256 Score = 38.5 bits (88), Expect = 0.043 Identities = 39/131 (29%), Positives = 61/131 (46%), Gaps = 19/131 (14%) Query: 423 SSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALAC--- 479 +SK EL +A+P Q+ E S+ S+ + N++S N S + EPS + Sbjct: 764 TSKVELTLASPYMKQEKEEEKEGFSE-SDFSDGNTSSNAESWRNPSSSEEEPSPVLKTLE 822 Query: 480 RSQNLKESSVKVDNESCCSRSNNKIQNAP-----SRKSVLTDPA----------KLKKLQ 524 RS K S +++ S S + K+ N P S + V T P KLK++ Sbjct: 823 RSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMS 882 Query: 525 QSGEAFVQDDS 535 +S AF+QD+S Sbjct: 883 KSVPAFLQDES 893 >gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens] Length = 739 Score = 36.6 bits (83), Expect = 0.16 Identities = 60/246 (24%), Positives = 90/246 (36%), Gaps = 25/246 (10%) Query: 309 PPSKDPRQQSTPQAANSPPNLGAKIPQG--CHKQSLPEEISSCLNTKSEALRTKPDVCKA 366 PPS P Q TP+ N + +K SCLN+K++ + T + K Sbjct: 413 PPSASPTQPQTPEGGGQWLNSSCAWSESSQLNKTRSIRRRDSCLNSKTKVMPTPTNQFKI 472 Query: 367 GLLS--KSSQIGTGDLKILTEPKGSCTQ----PKTNTDQENRLESVPQALTGLPK-ECLP 419 S S T L P+ SCT +T PQ+L + LP Sbjct: 473 PKFSIGDSPDSSTPKLSRAQRPQ-SCTSVGRVTVHSTPVRRSSGPAPQSLLSARRVSALP 531 Query: 420 TKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALAC 479 T AS + PP K + P V + V A S P S + EP+ + Sbjct: 532 TPASRRCS---GLPPMTPKTM-----PRAVGSPLCVPARRRSSEPRKNSAMRTEPTRESN 583 Query: 480 RSQNLKESSVKVDNESCCSRSNNKIQNAPSR------KSVLTDPAKLKKLQQSGEAFVQD 533 R + + V D S SR + +P KS T+ A+ ++ + G+A + Sbjct: 584 RKTDSRLVDVSPDRGSPPSRVPQALNFSPEESDSTFSKSTATEVAR-EEAKPGGDAAPSE 642 Query: 534 DSCVNI 539 V+I Sbjct: 643 ALLVDI 648 >gi|145199237 transcription elongation factor B polypeptide 3 binding protein 1 [Homo sapiens] Length = 1221 Score = 36.6 bits (83), Expect = 0.16 Identities = 55/231 (23%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query: 306 AATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCK 365 AAT P +P STP+A P P K+ L E TK A++ C Sbjct: 293 AATVPGNEPTTASTPKARADPEIKATGQPPS--KEGLEAEGGGLRETKETAVQ-----CD 345 Query: 366 AGLLSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPTKASSK 425 G L ++ + G C + ++ P G + K K Sbjct: 346 VGDLQPPPAKPASPAQVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGK---DKTKDK 402 Query: 426 AELEIANPPELQKHLEHAPSPSDVSNAPE-VKAGVNSDSPNNCSGKKVEPSALACRSQNL 484 P K A SP + PE K +S +P SGK P A R Sbjct: 403 GRGRPVEKPRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKG-RPDRPARR---- 457 Query: 485 KESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKL--KKLQQSGEAFVQD 533 S D+ R + P RKS KL +K + E QD Sbjct: 458 -PSPTSGDSRPAAGRGPPRPLQLPDRKSTKAPSGKLVERKARSLDEGASQD 507 >gi|239788849 jumonji domain containing 4 isoform 2 [Homo sapiens] Length = 447 Score = 36.2 bits (82), Expect = 0.21 Identities = 20/53 (37%), Positives = 30/53 (56%), Gaps = 6/53 (11%) Query: 1233 IVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQ 1285 I Q G++VF+P+G HQVHNL I + ++V+ F L +R+L Q Sbjct: 299 ITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNG------FNLANMWRFLQQ 345 >gi|239788847 jumonji domain containing 4 isoform 1 [Homo sapiens] Length = 463 Score = 36.2 bits (82), Expect = 0.21 Identities = 20/53 (37%), Positives = 30/53 (56%), Gaps = 6/53 (11%) Query: 1233 IVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQ 1285 I Q G++VF+P+G HQVHNL I + ++V+ F L +R+L Q Sbjct: 299 ITQEAGEMVFVPSGWHHQVHNLDDTISINHNWVNG------FNLANMWRFLQQ 345 >gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] Length = 935 Score = 36.2 bits (82), Expect = 0.21 Identities = 49/169 (28%), Positives = 71/169 (42%), Gaps = 20/169 (11%) Query: 387 KGSCTQPKTNTDQE-NRLESVPQALTGLPK--ECLPT------KASSKAELEIANPPELQ 437 K QP T+ N L S + LT P+ E PT K+S LE P Sbjct: 404 KSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPA 463 Query: 438 KHLEHA--PSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALA-CRSQNLKESS------ 488 L H P PS V S+ + K +E SA S++L++ S Sbjct: 464 DELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQ 523 Query: 489 VKVDNE-SCCSRSNNKIQNAPSRK-SVLTDPAKLKKLQQSGEAFVQDDS 535 KVDN+ RS + P++ + + P KLK++ +S AF+QD+S Sbjct: 524 AKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDES 572 >gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] Length = 934 Score = 36.2 bits (82), Expect = 0.21 Identities = 49/169 (28%), Positives = 71/169 (42%), Gaps = 20/169 (11%) Query: 387 KGSCTQPKTNTDQE-NRLESVPQALTGLPK--ECLPT------KASSKAELEIANPPELQ 437 K QP T+ N L S + LT P+ E PT K+S LE P Sbjct: 403 KSETHQPMTSGSFPINGLHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPA 462 Query: 438 KHLEHA--PSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALA-CRSQNLKESS------ 488 L H P PS V S+ + K +E SA S++L++ S Sbjct: 463 DELSHCVEPEPSQVPGGSSRDRQQGSEEEPSPVLKTLERSAARKMPSKSLEDISSDSSNQ 522 Query: 489 VKVDNE-SCCSRSNNKIQNAPSRK-SVLTDPAKLKKLQQSGEAFVQDDS 535 KVDN+ RS + P++ + + P KLK++ +S AF+QD+S Sbjct: 523 AKVDNQPEELVRSAEDVSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDES 571 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 36.2 bits (82), Expect = 0.21 Identities = 52/237 (21%), Positives = 96/237 (40%), Gaps = 24/237 (10%) Query: 263 KSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKEILLGCTAATP---PSKDPRQQST 319 KS E + ++AKS +EA + + V +E A +P +K P + + Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSP----EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS 634 Query: 320 PQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGLLSKSSQIGTGD 379 P+ A SP AK P+ K PE K EA P+ K+ + +++ Sbjct: 635 PEKAKSPTKEEAKSPE---KAKSPE--------KEEA--KSPEKAKSPVKAEAKSPEKAK 681 Query: 380 LKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECL-PTKASSKAELEIANPPELQK 438 + E K + K + + +S +A + + +E P KA S + E P + + Sbjct: 682 SPVKAEAK---SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKS 738 Query: 439 HLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSALACRSQNLKESSVKVDNES 495 ++ + + +PE ++ SP + K E + A + +S VK + +S Sbjct: 739 PVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKS 795 Score = 33.1 bits (74), Expect = 1.8 Identities = 62/260 (23%), Positives = 96/260 (36%), Gaps = 24/260 (9%) Query: 282 ASPSMCPVQSVPTTVFKEILLGCTAATPP---SKDPRQQSTPQAANSPPNLGAKIPQGCH 338 A + P + + V +E A +P +K P + +P+ A SP AK P Sbjct: 506 AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA- 564 Query: 339 KQSLPEEISSCLNTKSEALRTKP--DVCKAGLLSKSSQIGTGDLKILTEPKGSCTQPKTN 396 K EE S KS P + K+ +KS + +K E S + K+ Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK---EEAKSPAEAKSP 621 Query: 397 TDQENRLESVPQALTGLPKECLPTKASSKAELEIANP-PELQKHLEHAPSPSDVSNAPEV 455 +E + P + K PTK +K+ + +P E K E A SP E Sbjct: 622 VKEEAK---SPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA----EA 674 Query: 456 KAGVNSDSPNNCSGKKVE----PSALACRSQNLKESSVKVD---NESCCSRSNNKIQNAP 508 K+ + SP K E P +S +S VK + E S + + Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734 Query: 509 SRKSVLTDPAKLKKLQQSGE 528 KS + + AK + +S E Sbjct: 735 KAKSPVKEEAKSPEKAKSPE 754 >gi|197245440 hypothetical protein LOC23285 [Homo sapiens] Length = 1354 Score = 35.8 bits (81), Expect = 0.28 Identities = 63/284 (22%), Positives = 114/284 (40%), Gaps = 45/284 (15%) Query: 249 VTCGNSARIGAVKRKSSENNGTLVSKQAKSCSEASPSMCPVQSVPTTVFKE--ILLGCTA 306 VT G S + ++ ++ NN L K CSE VP + K+ GCTA Sbjct: 356 VTNGTSNKKSIHEQDTNVNNSVLKKVSGKGCSE---------PVPQAILKKRGTSNGCTA 406 Query: 307 ATPPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEA-----LRTKP 361 A R +STP +N G+ QG S+ +SS + ++ A T+ Sbjct: 407 A-----QQRTKSTP--SNLTKTQGS---QGESPNSVKSSVSSRQSDENVAKLDHNTTTEK 456 Query: 362 DVCKAGLLSK-SSQIGTGDLKILTEPKGSCTQPK----TNTDQENRL-------ESVPQA 409 K ++ + + + + KI+ PK K N D + ++ ++ P + Sbjct: 457 QAPKRKMVKQVHTALPKVNAKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSS 516 Query: 410 LTGLPKECLPTKASSKAEL-EIANPPELQKHLEHAP---SPSDVSNAPEVKAGVNSDSPN 465 L E + S ++ + N + + H P S++S+A +++ D Sbjct: 517 QRPLKHETSTVQKSMFHDVRDNNNKDSVSEQKPHKPLINLASEISDAEALQSSCRPDPQK 576 Query: 466 NCSGKKVEPSALACRSQNLKESSVKVDNES---CCSRSNNKIQN 506 + ++ E AL C++ + + S+K + ES C +S K N Sbjct: 577 PLNDQEKEKLALECQNISKLDKSLKHELESKQICLDKSETKFPN 620 >gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo sapiens] Length = 984 Score = 35.4 bits (80), Expect = 0.36 Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 10/126 (7%) Query: 249 VTCGNSARIGAVKRKSSENNGTLVSKQAKS---CSEASPSMCPVQSVPTTVFKEILLGCT 305 ++C N+ + S NG ++ KS C E SPS+C ++ ++V + Sbjct: 154 LSCVNTPLRSFMSDSGSSVNGGVMRAVVKSPIMCHEKSPSVCSPLNMTSSVCSPAGINSV 213 Query: 306 AATP------PSKDPRQQSTPQAAN-SPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALR 358 ++T P P Q TP + + N G++ H ++ +SS L++ ++ Sbjct: 214 SSTTASFGSFPVHSPITQGTPLTCSPNVENRGSRSHSPAHASNVGSPLSSPLSSMKSSIS 273 Query: 359 TKPDVC 364 + P C Sbjct: 274 SPPSHC 279 >gi|225543474 myotubularin related protein 7 [Homo sapiens] Length = 660 Score = 35.0 bits (79), Expect = 0.48 Identities = 39/129 (30%), Positives = 54/129 (41%), Gaps = 17/129 (13%) Query: 394 KTNTDQ-ENRLESVPQALTGLPKECLP-TKASSKAELEIANPPELQKHLEHAPSPSDVSN 451 K T Q E LE++ + L + K L TK SK E KH + S + ++N Sbjct: 525 KEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQS-------EPSKHSGFSTSDNSIAN 577 Query: 452 APEVKAGVNSDSPNNCSGKKVEPSALACRSQNLKES----SVKVDNES----CCSRSNNK 503 P+ +G P+ + E SAL NLK S S D ES RS + Sbjct: 578 TPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSG 637 Query: 504 IQNAPSRKS 512 ++APS S Sbjct: 638 GEHAPSEDS 646 >gi|118026921 asparagine-linked glycosylation 9 protein isoform a [Homo sapiens] Length = 618 Score = 35.0 bits (79), Expect = 0.48 Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 88 FLVEHNLVLAERKSPEISERIVQWPAITYKPLLDKAGLGSITS---VRFLGDQQRVFLSK 144 +LV+ + + + P+ S +W ++ Y+P LD + + V FL DQ V+++ Sbjct: 542 YLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNY 601 Query: 145 DLLKP 149 +LKP Sbjct: 602 TILKP 606 >gi|118026935 asparagine-linked glycosylation 9 protein isoform d [Homo sapiens] Length = 440 Score = 35.0 bits (79), Expect = 0.48 Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 88 FLVEHNLVLAERKSPEISERIVQWPAITYKPLLDKAGLGSITS---VRFLGDQQRVFLSK 144 +LV+ + + + P+ S +W ++ Y+P LD + + V FL DQ V+++ Sbjct: 364 YLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNY 423 Query: 145 DLLKP 149 +LKP Sbjct: 424 TILKP 428 >gi|118026937 asparagine-linked glycosylation 9 protein isoform c [Homo sapiens] Length = 447 Score = 35.0 bits (79), Expect = 0.48 Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 88 FLVEHNLVLAERKSPEISERIVQWPAITYKPLLDKAGLGSITS---VRFLGDQQRVFLSK 144 +LV+ + + + P+ S +W ++ Y+P LD + + V FL DQ V+++ Sbjct: 371 YLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNY 430 Query: 145 DLLKP 149 +LKP Sbjct: 431 TILKP 435 >gi|118026933 asparagine-linked glycosylation 9 protein isoform b [Homo sapiens] Length = 611 Score = 35.0 bits (79), Expect = 0.48 Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 88 FLVEHNLVLAERKSPEISERIVQWPAITYKPLLDKAGLGSITS---VRFLGDQQRVFLSK 144 +LV+ + + + P+ S +W ++ Y+P LD + + V FL DQ V+++ Sbjct: 535 YLVDLDTMRETPREPKYSSNKEEWISLAYRPFLDASRSSKLLRAFYVPFLSDQYTVYVNY 594 Query: 145 DLLKP 149 +LKP Sbjct: 595 TILKP 599 >gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo sapiens] Length = 1134 Score = 34.7 bits (78), Expect = 0.62 Identities = 48/198 (24%), Positives = 80/198 (40%), Gaps = 32/198 (16%) Query: 314 PRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKS----EALRTKPDVCKAGLL 369 P ++ P ++ + +IP+ L +S+ +S EALR K L Sbjct: 680 PEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLK 739 Query: 370 SKSSQIGTGDLKILTEPKGSCTQPKTNTDQENR-----LESVPQALTGLPKECLPTKASS 424 +SS +TEP+G P R +E++ ++ P + ASS Sbjct: 740 KRSS---------ITEPEGP-NGPNIQKLLYQRTTIAAMETI--SVPSYPSKSASVTASS 787 Query: 425 KAELEIANP-------PELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSAL 477 ++ +EI NP E+ + + SP DV NA + NSD P G EP + Sbjct: 788 ESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNA----STENSDMPAPSPGLDYEPEGV 843 Query: 478 ACRSQNLKESSVKVDNES 495 S NL+ + + + E+ Sbjct: 844 PDNSPNLQNNPEEPNPEA 861 >gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo sapiens] Length = 1005 Score = 34.7 bits (78), Expect = 0.62 Identities = 48/198 (24%), Positives = 80/198 (40%), Gaps = 32/198 (16%) Query: 314 PRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKS----EALRTKPDVCKAGLL 369 P ++ P ++ + +IP+ L +S+ +S EALR K L Sbjct: 551 PEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLK 610 Query: 370 SKSSQIGTGDLKILTEPKGSCTQPKTNTDQENR-----LESVPQALTGLPKECLPTKASS 424 +SS +TEP+G P R +E++ ++ P + ASS Sbjct: 611 KRSS---------ITEPEGP-NGPNIQKLLYQRTTIAAMETI--SVPSYPSKSASVTASS 658 Query: 425 KAELEIANP-------PELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSAL 477 ++ +EI NP E+ + + SP DV NA + NSD P G EP + Sbjct: 659 ESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNA----STENSDMPAPSPGLDYEPEGV 714 Query: 478 ACRSQNLKESSVKVDNES 495 S NL+ + + + E+ Sbjct: 715 PDNSPNLQNNPEEPNPEA 732 >gi|158631177 homeodomain leucine zipper protein [Homo sapiens] Length = 550 Score = 34.3 bits (77), Expect = 0.81 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 4/75 (5%) Query: 276 AKSCSEASPS-MCPVQSVPTTVFKEILLGCTAATPPSKD---PRQQSTPQAANSPPNLGA 331 A SC E S S + P S ++ F+ + G TAA+ P + Q +P PP+L Sbjct: 270 ASSCKEESASSVTPSSSSTSSSFQVLANGATAASKPLQPLGCVPQSVSPSEQALPPHLEP 329 Query: 332 KIPQGCHKQSLPEEI 346 PQG S+P + Sbjct: 330 AWPQGLRHNSVPGRV 344 >gi|189011568 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 33.9 bits (76), Expect = 1.1 Identities = 53/229 (23%), Positives = 91/229 (39%), Gaps = 31/229 (13%) Query: 309 PPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGL 368 PP K P +S + + + P+G K S+ E+S S+ + ++G Sbjct: 2251 PPLKTPASKSPSEGQTATTS-----PRGA-KPSVKSELSPVARQTSQIGGSSKAPSRSG- 2303 Query: 369 LSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLE-SVPQALTGLPKECLPTKASSKA- 426 S+ S + L+ P S P N+ R S P L+ LP+ P+ AS+K+ Sbjct: 2304 -SRDSTPSRPAQQPLSRPIQS---PGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSS 2359 Query: 427 ---ELEIANP------PELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSAL 477 ++ +P L K + + S + + G+N + N + KKVE S + Sbjct: 2360 GSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRM 2419 Query: 478 ACRSQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQS 526 + + ES R + I+ APS P +KL++S Sbjct: 2420 SSTKSSGSESD--RSERPVLVRQSTFIKEAPS-------PTLRRKLEES 2459 >gi|189011566 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 33.9 bits (76), Expect = 1.1 Identities = 53/229 (23%), Positives = 91/229 (39%), Gaps = 31/229 (13%) Query: 309 PPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGL 368 PP K P +S + + + P+G K S+ E+S S+ + ++G Sbjct: 2251 PPLKTPASKSPSEGQTATTS-----PRGA-KPSVKSELSPVARQTSQIGGSSKAPSRSG- 2303 Query: 369 LSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLE-SVPQALTGLPKECLPTKASSKA- 426 S+ S + L+ P S P N+ R S P L+ LP+ P+ AS+K+ Sbjct: 2304 -SRDSTPSRPAQQPLSRPIQS---PGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSS 2359 Query: 427 ---ELEIANP------PELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSAL 477 ++ +P L K + + S + + G+N + N + KKVE S + Sbjct: 2360 GSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRM 2419 Query: 478 ACRSQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQS 526 + + ES R + I+ APS P +KL++S Sbjct: 2420 SSTKSSGSESD--RSERPVLVRQSTFIKEAPS-------PTLRRKLEES 2459 >gi|53759122 adenomatous polyposis coli [Homo sapiens] Length = 2843 Score = 33.9 bits (76), Expect = 1.1 Identities = 53/229 (23%), Positives = 91/229 (39%), Gaps = 31/229 (13%) Query: 309 PPSKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGL 368 PP K P +S + + + P+G K S+ E+S S+ + ++G Sbjct: 2251 PPLKTPASKSPSEGQTATTS-----PRGA-KPSVKSELSPVARQTSQIGGSSKAPSRSG- 2303 Query: 369 LSKSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLE-SVPQALTGLPKECLPTKASSKA- 426 S+ S + L+ P S P N+ R S P L+ LP+ P+ AS+K+ Sbjct: 2304 -SRDSTPSRPAQQPLSRPIQS---PGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSS 2359 Query: 427 ---ELEIANP------PELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVEPSAL 477 ++ +P L K + + S + + G+N + N + KKVE S + Sbjct: 2360 GSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRM 2419 Query: 478 ACRSQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAKLKKLQQS 526 + + ES R + I+ APS P +KL++S Sbjct: 2420 SSTKSSGSESD--RSERPVLVRQSTFIKEAPS-------PTLRRKLEES 2459 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 33.5 bits (75), Expect = 1.4 Identities = 38/157 (24%), Positives = 57/157 (36%), Gaps = 16/157 (10%) Query: 311 SKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGLLS 370 SKDP +S+ +A +PP + C K +E T KP A S Sbjct: 559 SKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQ-RQTVGTKQPKKPVKASARAGS 617 Query: 371 KSSQIGTGDLKILTEPKGSCTQPKTNTDQENRLESVPQALTGLPKECLPTKASSKAELEI 430 ++S G + +L P GS Q + + A + PK +P + K Sbjct: 618 RTSLQGEREPGLL--PYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKK----- 670 Query: 431 ANPPELQKHLEHAPSPSDVSNAPE-VKAGVNSDSPNN 466 KH P+PS + PE K V +P + Sbjct: 671 -------KHKSSLPAPSKALSGPEPAKDNVEDRTPEH 700 Score = 32.3 bits (72), Expect = 3.1 Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 15/163 (9%) Query: 311 SKDPRQQSTPQAANSPPNLGAKIPQGCHKQSLPEEISSCLNTKSEALRTKPDVCKAGLLS 370 S+D + TP+ PP+ A P QSLPE ++S ++ +E+ T + S Sbjct: 432 SEDSDSEQTPE---KPPSSSAP-PSA--PQSLPEPVASAHSSSAESESTSDSDSSSDSES 485 Query: 371 KSSQIGTGDLKILTEPKGSCTQPKTNTDQ-ENRLESV--PQALTGLPKECLPTK--ASSK 425 +SS + + + L P P TN Q +N L V P A P+ P + SK Sbjct: 486 ESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESK 545 Query: 426 AELEIANPPELQKHLEHA-PSPSDVSNAPEVKAGVNSDSPNNC 467 + A Q+H E P P S AP +C Sbjct: 546 GSSDSATS---QEHSESKDPPPKSSSKAPRAPPEAPHPGKRSC 585 Score = 31.6 bits (70), Expect = 5.3 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 10/122 (8%) Query: 419 PTKASSKAELEIANPPELQKHLEHAPSPSDVSNAPEVKAGVNSDSPNNCSGKKVE----- 473 P K S + + E PP +KH S S + + G ++ +C KK+ Sbjct: 777 PGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKG---EAERDCDNKKIRLEKEI 833 Query: 474 PSALACRSQNLKESSVKVDNESCCSRSNNKIQNAPSRKSVLTDPAK--LKKLQQSGEAFV 531 S + S + KESS + S ++ P S PAK LK+ ++ + Sbjct: 834 KSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSRREADTCG 893 Query: 532 QD 533 QD Sbjct: 894 QD 895 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,333,607 Number of Sequences: 37866 Number of extensions: 2671419 Number of successful extensions: 8444 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 68 Number of HSP's that attempted gapping in prelim test: 8277 Number of HSP's gapped (non-prelim): 233 length of query: 1321 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1207 effective length of database: 13,930,794 effective search space: 16814468358 effective search space used: 16814468358 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.