Guide to the Human Genome
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Search of human proteins with 226342962

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
         (600 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]              1217   0.0  
gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]              1206   0.0  
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]              1092   0.0  
gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens]              1080   0.0  
gi|123173752 synaptotagmin XIV-like [Homo sapiens]                    436   e-122
gi|209447073 synaptotagmin I [Homo sapiens]                           122   9e-28
gi|5032139 synaptotagmin I [Homo sapiens]                             122   9e-28
gi|209447070 synaptotagmin I [Homo sapiens]                           122   9e-28
gi|39752671 synaptotagmin X [Homo sapiens]                            115   1e-25
gi|211059429 synaptotagmin II [Homo sapiens]                          111   2e-24
gi|31543670 synaptotagmin II [Homo sapiens]                           111   2e-24
gi|24308219 synaptotagmin IV [Homo sapiens]                           110   3e-24
gi|216548478 synaptotagmin XI [Homo sapiens]                          107   3e-23
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]            105   1e-22
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]             105   1e-22
gi|45504376 synaptotagmin VI [Homo sapiens]                           105   1e-22
gi|38570146 synaptotagmin VII [Homo sapiens]                          104   3e-22
gi|238550198 synaptotagmin III [Homo sapiens]                         100   4e-21
gi|238550196 synaptotagmin III [Homo sapiens]                         100   4e-21
gi|14150054 synaptotagmin III [Homo sapiens]                          100   4e-21
gi|92859638 synaptotagmin V [Homo sapiens]                             99   1e-20
gi|28376627 synaptotagmin IX [Homo sapiens]                            94   5e-19
gi|6005997 double C2-like domains, beta [Homo sapiens]                 92   2e-18
gi|40068038 B/K protein [Homo sapiens]                                 88   2e-17
gi|29366828 synaptotagmin XII [Homo sapiens]                           88   3e-17
gi|47078261 double C2-like domains, alpha [Homo sapiens]               83   6e-16
gi|31881675 synaptotagmin XV isoform a [Homo sapiens]                  83   8e-16
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap...    81   3e-15
gi|94536846 synaptotagmin VIII [Homo sapiens]                          79   9e-15
gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]             68   2e-11

>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
          Length = 600

 Score = 1217 bits (3149), Expect = 0.0
 Identities = 600/600 (100%), Positives = 600/600 (100%)

Query: 1   MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60
           MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ
Sbjct: 1   MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60

Query: 61  VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120
           VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI
Sbjct: 61  VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120

Query: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180
           YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE
Sbjct: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180

Query: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240
           YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS
Sbjct: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240

Query: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300
           NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP
Sbjct: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300

Query: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360
           EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS
Sbjct: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360

Query: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
           IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM
Sbjct: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420

Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480
           SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE
Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480

Query: 481 VIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ 540
           VIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ
Sbjct: 481 VIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ 540

Query: 541 LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600
           LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES
Sbjct: 541 LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600


>gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]
          Length = 619

 Score = 1206 bits (3119), Expect = 0.0
 Identities = 600/619 (96%), Positives = 600/619 (96%), Gaps = 19/619 (3%)

Query: 1   MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60
           MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ
Sbjct: 1   MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60

Query: 61  VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120
           VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI
Sbjct: 61  VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120

Query: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180
           YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE
Sbjct: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180

Query: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240
           YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS
Sbjct: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240

Query: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300
           NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP
Sbjct: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300

Query: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360
           EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS
Sbjct: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360

Query: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
           IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM
Sbjct: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420

Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480
           SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE
Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480

Query: 481 VIKGSHFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRR 521
           VIKGSHFKNLAANRPPN                   TYVKLTLLNSMGQEMSKCKTSIRR
Sbjct: 481 VIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRR 540

Query: 522 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 581
           GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT
Sbjct: 541 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 600

Query: 582 EMKESKGQQVCRWHALLES 600
           EMKESKGQQVCRWHALLES
Sbjct: 601 EMKESKGQQVCRWHALLES 619


>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
          Length = 555

 Score = 1092 bits (2823), Expect = 0.0
 Identities = 535/535 (100%), Positives = 535/535 (100%)

Query: 66  VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125
           VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM
Sbjct: 21  VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80

Query: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185
           DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS
Sbjct: 81  DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140

Query: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245
           SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC
Sbjct: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200

Query: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305
           SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK
Sbjct: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260

Query: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365
           YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP
Sbjct: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320

Query: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
           CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI
Sbjct: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380

Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
           LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS
Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440

Query: 486 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 545
           HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT
Sbjct: 441 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 500

Query: 546 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600
           LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES
Sbjct: 501 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 555


>gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens]
          Length = 574

 Score = 1080 bits (2793), Expect = 0.0
 Identities = 535/554 (96%), Positives = 535/554 (96%), Gaps = 19/554 (3%)

Query: 66  VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125
           VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM
Sbjct: 21  VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80

Query: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185
           DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS
Sbjct: 81  DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140

Query: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245
           SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC
Sbjct: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200

Query: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305
           SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK
Sbjct: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260

Query: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365
           YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP
Sbjct: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320

Query: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
           CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI
Sbjct: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380

Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
           LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS
Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440

Query: 486 HFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRRGQPNP 526
           HFKNLAANRPPN                   TYVKLTLLNSMGQEMSKCKTSIRRGQPNP
Sbjct: 441 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 500

Query: 527 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 586
           VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES
Sbjct: 501 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 560

Query: 587 KGQQVCRWHALLES 600
           KGQQVCRWHALLES
Sbjct: 561 KGQQVCRWHALLES 574


>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
          Length = 645

 Score =  436 bits (1120), Expect = e-122
 Identities = 244/485 (50%), Positives = 327/485 (67%), Gaps = 15/485 (3%)

Query: 119 KIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSP-- 176
           K  NS+ D +E  +SS+S++E + ++  ++SR+ + R  +   + +    E + K+S   
Sbjct: 173 KQVNSFGDDEELSTSSDSDEEVIKQFEISVSRSQSFR-SVTSEKGKQTGLEQKPKFSRSL 231

Query: 177 LSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCE- 235
           L+   DG    A  D     QR R +  L       Y +D   P  S +P E GD+K   
Sbjct: 232 LTHGEDGTEVSACEDLDGASQR-RYSENLS------YGEDDHIPAHSQSPCERGDAKHHG 284

Query: 236 FSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP 295
            SH  +S   S  +  +EGS   E  +F+++G+E+   +DS+++ SPE+     ++ Q+P
Sbjct: 285 TSHQESSVVQSLRRQSTEGSLEMET-AFNSRGFEDSYATDSSSMWSPEEQDR--TNLQVP 341

Query: 296 KPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQ 355
                EP +K G LDV F+Y +  QKL VT+     +P  +R+G NSWQVH+VLLP KK 
Sbjct: 342 SGVS-EPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPGKKH 400

Query: 356 RAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLN 415
           R +T+IQRGP PVF E   F  +E   +   AVRFRLY   +M +E+++GEK+FYL+ L+
Sbjct: 401 RGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLH 460

Query: 416 LQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTG 475
            +G+M + ++LEP  N S   S +S S +S S+STSS QSL HG  PE+L+GL YNATTG
Sbjct: 461 PEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTG 520

Query: 476 RLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQ 535
           RLS E+IKGSHF+NLA NR P+TY KL LLNS+GQEMS+CKTSIRRGQPNPVYKETFVFQ
Sbjct: 521 RLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQ 580

Query: 536 VALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWH 595
           VALFQLSDVTL++SVYN+R+MKRKEMIGWI+LG NSSGEEE +HW EMKE+KGQQ+CRWH
Sbjct: 581 VALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWH 640

Query: 596 ALLES 600
            LLES
Sbjct: 641 TLLES 645


>gi|209447073 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  122 bits (306), Expect = 9e-28
 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)

Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
           +P+ E K G L  + DYD Q  +LLV +    ++P  +  G +   V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195

Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
           T + R    PVF E F F    SE+ G   V   +Y   R  K  I+GE           
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244

Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
            K+ +  +          D Q +  E             E   + +I   L Y  T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290

Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
           +  +++  + K +      + YVK+ L+ + G+ + K KT+I++   NP Y E+F F+V 
Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349

Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
             Q+  V ++++V +   + + + IG + +G NS+G  EL HW++M  +  + + +WH L
Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)

Query: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501
           +E   ++     +  E   + ++   L Y+    +L   +I+ +    L      + YVK
Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183

Query: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561
           + LL     +  K +T + R   NPV+ E F F+V   +L   TL+++VY+     + ++
Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240

Query: 562 IGWISLGLNSSGEEELNHWTE 582
           IG   + +N+    +  H TE
Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258


>gi|5032139 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  122 bits (306), Expect = 9e-28
 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)

Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
           +P+ E K G L  + DYD Q  +LLV +    ++P  +  G +   V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195

Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
           T + R    PVF E F F    SE+ G   V   +Y   R  K  I+GE           
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244

Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
            K+ +  +          D Q +  E             E   + +I   L Y  T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290

Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
           +  +++  + K +      + YVK+ L+ + G+ + K KT+I++   NP Y E+F F+V 
Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349

Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
             Q+  V ++++V +   + + + IG + +G NS+G  EL HW++M  +  + + +WH L
Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)

Query: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501
           +E   ++     +  E   + ++   L Y+    +L   +I+ +    L      + YVK
Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183

Query: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561
           + LL     +  K +T + R   NPV+ E F F+V   +L   TL+++VY+     + ++
Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240

Query: 562 IGWISLGLNSSGEEELNHWTE 582
           IG   + +N+    +  H TE
Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258


>gi|209447070 synaptotagmin I [Homo sapiens]
          Length = 422

 Score =  122 bits (306), Expect = 9e-28
 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%)

Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
           +P+ E K G L  + DYD Q  +LLV +    ++P  +  G +   V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195

Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
           T + R    PVF E F F    SE+ G   V   +Y   R  K  I+GE           
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244

Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
            K+ +  +          D Q +  E             E   + +I   L Y  T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290

Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
           +  +++  + K +      + YVK+ L+ + G+ + K KT+I++   NP Y E+F F+V 
Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349

Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
             Q+  V ++++V +   + + + IG + +G NS+G  EL HW++M  +  + + +WH L
Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%)

Query: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501
           +E   ++     +  E   + ++   L Y+    +L   +I+ +    L      + YVK
Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183

Query: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561
           + LL     +  K +T + R   NPV+ E F F+V   +L   TL+++VY+     + ++
Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240

Query: 562 IGWISLGLNSSGEEELNHWTE 582
           IG   + +N+    +  H TE
Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258


>gi|39752671 synaptotagmin X [Homo sapiens]
          Length = 523

 Score =  115 bits (288), Expect = 1e-25
 Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 33/297 (11%)

Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
           G L+ T  YD + + L+V +    D+P  + TG +   V + LLP +K++ +T + R   
Sbjct: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTL 292

Query: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
            P+F ETF+F  V  + + N  + F +Y   R  +  ++GE I                 
Sbjct: 293 NPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL---------------- 335

Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSS---CQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
                     D+   VS++S   +      C + E   + EI+  L Y  T GR++  VI
Sbjct: 336 ----------DNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVI 385

Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542
           K  + K +      + YVK++L+   G+ + K KT+ ++   NPVY E  +F +    + 
Sbjct: 386 KCRNLKAMDITGSSDPYVKVSLMCE-GRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVD 444

Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
            V+L ++V +   +   E+IG    GL++ G    +HW EM     + +  WH LLE
Sbjct: 445 QVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITHWHPLLE 500


>gi|211059429 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  111 bits (278), Expect = 2e-24
 Identities = 78/300 (26%), Positives = 142/300 (47%), Gaps = 29/300 (9%)

Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
           + EPE   G L  + DYD Q  +L V V    ++P  +  G +   V + LLP KK++ +
Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192

Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
           T + R    P F ETF F  V  + +G   +   +Y   R  K  I+GE           
Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240

Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
             + +P+        +  D    + E          +  E   + +I   L Y  T G+L
Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287

Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
           +  +++  + K +      + YVK+ L+ + G+ + K KT++++   NP + E+F F++ 
Sbjct: 288 TVCILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTVKKKTLNPYFNESFSFEIP 346

Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
             Q+  V ++++V +   + + E IG I +G N++G  EL HW++M  +  + + +WH+L
Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSL 405


>gi|31543670 synaptotagmin II [Homo sapiens]
          Length = 419

 Score =  111 bits (278), Expect = 2e-24
 Identities = 78/300 (26%), Positives = 142/300 (47%), Gaps = 29/300 (9%)

Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
           + EPE   G L  + DYD Q  +L V V    ++P  +  G +   V + LLP KK++ +
Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192

Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
           T + R    P F ETF F  V  + +G   +   +Y   R  K  I+GE           
Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240

Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
             + +P+        +  D    + E          +  E   + +I   L Y  T G+L
Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287

Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
           +  +++  + K +      + YVK+ L+ + G+ + K KT++++   NP + E+F F++ 
Sbjct: 288 TVCILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTVKKKTLNPYFNESFSFEIP 346

Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
             Q+  V ++++V +   + + E IG I +G N++G  EL HW++M  +  + + +WH+L
Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSL 405


>gi|24308219 synaptotagmin IV [Homo sapiens]
          Length = 425

 Score =  110 bits (276), Expect = 3e-24
 Identities = 82/323 (25%), Positives = 146/323 (45%), Gaps = 35/323 (10%)

Query: 280 LSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTG 339
           +SPE + +  S +        E + K GTL  + +Y+ + +  +V +     +P  +   
Sbjct: 134 VSPESLKSSTSLTS------EEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187

Query: 340 GNSWQ-VHLVLLPIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHR 397
             S   + + +LP KK + KT + R    P F ETF F  +    I   A+ F +    R
Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247

Query: 398 MKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSL 456
             ++ I+GE +  L+ + L +GKM +                  + + +  +S+      
Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLM---------------NREIIKRNVRKSSGR---- 288

Query: 457 EHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK 516
                 E+LI L Y +TT  L+  V+K  H      +   + YVK+ L ++  + +SK K
Sbjct: 289 -----GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK-KRISKKK 342

Query: 517 TSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEE 576
           T +++  PN V+ E FVF +    L D+++   V +     R E+IG + LG  + G   
Sbjct: 343 THVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGG 402

Query: 577 LNHWTEMKESKGQQVCRWHALLE 599
             HW E+ +   +Q+ +WH L +
Sbjct: 403 -EHWKEICDYPRRQIAKWHVLCD 424


>gi|216548478 synaptotagmin XI [Homo sapiens]
          Length = 431

 Score =  107 bits (267), Expect = 3e-23
 Identities = 85/358 (23%), Positives = 160/358 (44%), Gaps = 36/358 (10%)

Query: 246 SYNKCPSEGSTGHEIESFHNK-GYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEA 304
           S +K P   S+G  I+    K  Y E++ S  T++   E        S+   P  PE + 
Sbjct: 105 SRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGE--------SKTTSPSSPEEDV 156

Query: 305 KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYN-RTGGNSWQVHLVLLPIKKQRAKTSIQR 363
             G+L  + DY+  ++ L+VT+     +P  + +T G+   + + +LP K+ R KT + R
Sbjct: 157 MLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLR 216

Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
               PVF ETF F  +    + +  + F +    R  ++ ++GE +  L  +        
Sbjct: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV-------- 268

Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
               +PS        ++ ++      +   C S       E+ + L Y     R++  V+
Sbjct: 269 ----DPS------TGKVQLTRDIIKRNIQKCISRG-----ELQVSLSYQPVAQRMTVVVL 313

Query: 483 KGSHFKNL-AANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQL 541
           K  H   +       N YVK+ +     + ++K KT +++   NP++ E+F++ +    L
Sbjct: 314 KARHLPKMDITGLSGNPYVKVNVYYGR-KRIAKKKTHVKKCTLNPIFNESFIYDIPTDLL 372

Query: 542 SDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
            D+++   V +     + E++G + LG +S       HW E+ ES  + V +WH+L E
Sbjct: 373 PDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score =  105 bits (262), Expect = 1e-22
 Identities = 109/435 (25%), Positives = 177/435 (40%), Gaps = 27/435 (6%)

Query: 182 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 237
           D   S A +   N +Q  R  P   +   PP     G+P  S   P   G   D K E +
Sbjct: 259 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 318

Query: 238 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 295
                        P E  TG  +  +   G  ED  S  +   S    +A    ++ Q P
Sbjct: 319 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 373

Query: 296 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 346
            P + E EA           G L+ +  YD     L  T+     +   +  G     V 
Sbjct: 374 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 433

Query: 347 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 402
           L LLP      K R KT ++    P++ ET  ++ +  E +    +R  +    +    +
Sbjct: 434 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 492

Query: 403 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 462
            +GE  F L KL    + +  + LE         +  S   M+  E     +  +     
Sbjct: 493 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 552

Query: 463 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRG 522
           +IL+ L+Y+   G L   +I+  H   + AN   + +VKL L   MG++ +K KT I++ 
Sbjct: 553 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK-AKHKTQIKKK 611

Query: 523 QPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTE 582
             NP + E F + +    L+  +L +SV++    K  + IG   LG+++ G E L HW E
Sbjct: 612 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ERLKHWYE 670

Query: 583 MKESKGQQVCRWHAL 597
             ++K +++ RWH L
Sbjct: 671 CLKNKDKKIERWHQL 685


>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
          Length = 690

 Score =  105 bits (262), Expect = 1e-22
 Identities = 109/435 (25%), Positives = 177/435 (40%), Gaps = 27/435 (6%)

Query: 182 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 237
           D   S A +   N +Q  R  P   +   PP     G+P  S   P   G   D K E +
Sbjct: 255 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 314

Query: 238 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 295
                        P E  TG  +  +   G  ED  S  +   S    +A    ++ Q P
Sbjct: 315 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 369

Query: 296 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 346
            P + E EA           G L+ +  YD     L  T+     +   +  G     V 
Sbjct: 370 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 429

Query: 347 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 402
           L LLP      K R KT ++    P++ ET  ++ +  E +    +R  +    +    +
Sbjct: 430 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 488

Query: 403 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 462
            +GE  F L KL    + +  + LE         +  S   M+  E     +  +     
Sbjct: 489 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 548

Query: 463 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRG 522
           +IL+ L+Y+   G L   +I+  H   + AN   + +VKL L   MG++ +K KT I++ 
Sbjct: 549 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK-AKHKTQIKKK 607

Query: 523 QPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTE 582
             NP + E F + +    L+  +L +SV++    K  + IG   LG+++ G E L HW E
Sbjct: 608 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ERLKHWYE 666

Query: 583 MKESKGQQVCRWHAL 597
             ++K +++ RWH L
Sbjct: 667 CLKNKDKKIERWHQL 681


>gi|45504376 synaptotagmin VI [Homo sapiens]
          Length = 425

 Score =  105 bits (262), Expect = 1e-22
 Identities = 77/294 (26%), Positives = 139/294 (47%), Gaps = 27/294 (9%)

Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
           G ++ +  YD + + L+V +    D+P  +  G +   V + LLP +K + +T + R   
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTL 205

Query: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
            P F E F F  V  E + +  +   ++   R  +  ++GE                 VI
Sbjct: 206 NPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGE-----------------VI 247

Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
           L+  +  S    + S+ +       ++ +S++ G   EI+  L Y  T GRL+  VIK  
Sbjct: 248 LDNLFEASDLSRETSIWK---DIQYATSESVDLG---EIMFSLCYLPTAGRLTLTVIKCR 301

Query: 486 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 545
           + K +      + YVK++LL   G+ + K KT+I++   NPVY E  +F +    +  V+
Sbjct: 302 NLKAMDITGYSDPYVKVSLLCD-GRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS 360

Query: 546 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
           L++SV +   +   E+IG   +G+ + G    +HW EM     + +  WH+L+E
Sbjct: 361 LLISVMDYDRVGHNEIIGVCRVGITAEGLGR-DHWNEMLAYPRKPIAHWHSLVE 413


>gi|38570146 synaptotagmin VII [Homo sapiens]
          Length = 403

 Score =  104 bits (259), Expect = 3e-22
 Identities = 87/351 (24%), Positives = 149/351 (42%), Gaps = 31/351 (8%)

Query: 248 NKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG 307
           N  P  G T H+ ES         V     ++ S   M + GS     +  +       G
Sbjct: 81  NTAPVPGQTPHD-ESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEED--EAHEGCSRENLG 137

Query: 308 TLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC- 366
            +  +  Y+ QE  L V +    ++P  + +G +   V + LLP KK + +T ++R    
Sbjct: 138 RIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLN 197

Query: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426
           P + ETF F     E +    +  ++    R  +   +GE    L K++L    +    L
Sbjct: 198 PHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDL 257

Query: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486
           +P                 CS+ +        GS  E+L+ L YN +   +   +IK  +
Sbjct: 258 KP-----------------CSDGS--------GSRGELLLSLCYNPSANSIIVNIIKARN 292

Query: 487 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 546
            K +      + YVK+ L+    + + K KT   +   NP++ E+F F +   +L + T+
Sbjct: 293 LKAMDIGGTSDPYVKVWLMYK-DKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTI 351

Query: 547 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
           I++V +K  + R ++IG I L    SG  E+ HW +M     Q V +WH L
Sbjct: 352 IITVMDKDKLSRNDVIGKIYLSW-KSGPGEVKHWKDMIARPRQPVAQWHQL 401


>gi|238550198 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  100 bits (249), Expect = 4e-21
 Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%)

Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363
           A  G +     Y     +L+V +    D+P  +  G +   V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357

Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
               PVF ETF+F+   +E+     + F +Y   R  +  ++G+ +             L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403

Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
             +LE +           + E             E   + E+   L Y  T GRL+  +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453

Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542
           K S+ K +      + YVK +L+ S G+ + K KTSI++   NP Y E  VF VA   + 
Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512

Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
           +V L ++V +   +   E+IG   +G +++      HW EM  +  + V  WH L+E
Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569


>gi|238550196 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  100 bits (249), Expect = 4e-21
 Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%)

Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363
           A  G +     Y     +L+V +    D+P  +  G +   V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357

Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
               PVF ETF+F+   +E+     + F +Y   R  +  ++G+ +             L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403

Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
             +LE +           + E             E   + E+   L Y  T GRL+  +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453

Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542
           K S+ K +      + YVK +L+ S G+ + K KTSI++   NP Y E  VF VA   + 
Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512

Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
           +V L ++V +   +   E+IG   +G +++      HW EM  +  + V  WH L+E
Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569


>gi|14150054 synaptotagmin III [Homo sapiens]
          Length = 590

 Score =  100 bits (249), Expect = 4e-21
 Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%)

Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363
           A  G +     Y     +L+V +    D+P  +  G +   V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357

Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
               PVF ETF+F+   +E+     + F +Y   R  +  ++G+ +             L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403

Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
             +LE +           + E             E   + E+   L Y  T GRL+  +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453

Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542
           K S+ K +      + YVK +L+ S G+ + K KTSI++   NP Y E  VF VA   + 
Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512

Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
           +V L ++V +   +   E+IG   +G +++      HW EM  +  + V  WH L+E
Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569


>gi|92859638 synaptotagmin V [Homo sapiens]
          Length = 386

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 79/308 (25%), Positives = 135/308 (43%), Gaps = 32/308 (10%)

Query: 295 PKPFDPEPEA----KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLL 350
           P P  P  +     + G L  + DYD Q  +LLV +     +   +  G +   V + LL
Sbjct: 94  PAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLL 153

Query: 351 PIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF 409
           P K++R +T + R    P F ETF F     E+ G   V   +Y   R  +   +GE   
Sbjct: 154 PDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLV-MAVYDFDRFSRNDAIGEVRV 212

Query: 410 YLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLL 469
            ++ ++L      PV                           +    E   + +I   L 
Sbjct: 213 PMSSVDL----GRPV--------------------QAWRELQAAPREEQEKLGDICFSLR 248

Query: 470 YNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYK 529
           Y  T G+L+  V++  + K +      + YVK+ LL   G+++ K KT+I++   NP Y 
Sbjct: 249 YVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG-GKKVRKKKTTIKKNTLNPYYN 307

Query: 530 ETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQ 589
           E F F+V   Q+  V + L+V +   + + E IG +++G  ++G   L HW +M  +  +
Sbjct: 308 EAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRR 366

Query: 590 QVCRWHAL 597
            + +WH+L
Sbjct: 367 PIAQWHSL 374



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 3/134 (2%)

Query: 438 QMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPN 497
           Q  V E+  + S    Q  +   +  +   L Y+  +G+L   +++      L      +
Sbjct: 86  QPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSD 145

Query: 498 TYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMK 557
            YV++ LL     +  + +T + R   NP + ETF F+V   +L    L+++VY+     
Sbjct: 146 PYVRVYLLPD---KRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFS 202

Query: 558 RKEMIGWISLGLNS 571
           R + IG + + ++S
Sbjct: 203 RNDAIGEVRVPMSS 216


>gi|28376627 synaptotagmin IX [Homo sapiens]
          Length = 491

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 74/300 (24%), Positives = 133/300 (44%), Gaps = 39/300 (13%)

Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
           G L+    YD   ++L+V +    ++P  + +G +   V + LLP +K + +T + R   
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281

Query: 367 -PVFTETFKF----NHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF--YLTKLNLQGK 419
            PVF E F F    N +E+  +      F +Y   R  +  ++G+ +   +L   +   +
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKL-----HFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRE 336

Query: 420 MSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSA 479
             L   +E   N                         ++  + E++  L Y  T GRL+ 
Sbjct: 337 CILWKDIEYVTN-------------------------DNVDLGELMFSLCYLPTAGRLTI 371

Query: 480 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALF 539
            +IK  + K +      + YVK++L+   G+ + K KTS +R   NPVY E  VF V   
Sbjct: 372 TIIKARNLKAMDITGASDPYVKVSLMCD-GRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430

Query: 540 QLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
            +  + L ++V +   +   E+IG   +G N +     +HW+EM     + +  WH+L+E
Sbjct: 431 NIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489


>gi|6005997 double C2-like domains, beta [Homo sapiens]
          Length = 412

 Score = 91.7 bits (226), Expect = 2e-18
 Identities = 92/361 (25%), Positives = 156/361 (43%), Gaps = 35/361 (9%)

Query: 251 PSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP-KPFDPEPEAK---- 305
           P+    G    S   +  +EDV     A  S    S   S ++ P KP + EP+A     
Sbjct: 62  PAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYES 121

Query: 306 -----YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLP----IKKQR 356
                 GTLD +  YD +   L  T+T    +   +  G     V L LLP      K R
Sbjct: 122 DDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLR 181

Query: 357 AKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL 416
            KT ++    P + ET  +  +  E +    +R  +    + +  + +GE    L KL  
Sbjct: 182 TKT-LRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKP 240

Query: 417 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 476
               +  + LE          Q+ V +       +  +SLE      ILI L Y++    
Sbjct: 241 NHTKTFNICLE---------KQLPVDK-------TEDKSLEERG--RILISLKYSSQKQG 282

Query: 477 LSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQV 536
           L   +++ +H   + AN   + YVK T L     + SK KT++++   NP + E F +++
Sbjct: 283 LLVGIVRCAHLAAMDANGYSDPYVK-TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEI 341

Query: 537 ALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHA 596
               L+  +L ++V++    K  + IG + LG+++ G E L HW +  ++K +++ RWH 
Sbjct: 342 KHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKG-ERLKHWFDCLKNKDKRIERWHT 400

Query: 597 L 597
           L
Sbjct: 401 L 401


>gi|40068038 B/K protein [Homo sapiens]
          Length = 474

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 84/338 (24%), Positives = 142/338 (42%), Gaps = 43/338 (12%)

Query: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKY--GTLDVTFDYDSQEQKLLVTVTAVT 330
           P D      P   S   +S  +    D E  +KY  G L  +  YD     L V V    
Sbjct: 150 PDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEAR 209

Query: 331 DIPT-YNRTGGNSWQVH------LVLLPIKKQRAKTSIQRGPC-PVFTE--TFKFNHVES 380
           D+P   +  G      H      + LLP +K   +T ++R    PVF E  TF+   +E+
Sbjct: 210 DLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEA 269

Query: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQM 439
           +      +   +    +  +  ++G+    L +++L +G      ++  S N        
Sbjct: 270 Q---RRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNE------- 319

Query: 440 SVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTY 499
                           +E G   E+L+ L Y  + GRL+ +VI+         ++  + +
Sbjct: 320 ----------------VELG---ELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF 360

Query: 500 VKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRK 559
           VK+ L++ +    +K KTS  RG  +P Y E+F F+V   +L + +L+ +V+        
Sbjct: 361 VKIQLVHGLKLVKTK-KTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSN 419

Query: 560 EMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
           + IG I +G  SSG  E NHW  M  +    V +WH+L
Sbjct: 420 DFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457


>gi|29366828 synaptotagmin XII [Homo sapiens]
          Length = 421

 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 72/291 (24%), Positives = 129/291 (44%), Gaps = 26/291 (8%)

Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
           G ++V+ +YD+    L V V    D+         S  + + LLP ++    + IQR   
Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213

Query: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426
            +F +      ++   +   ++RF ++G+   ++    G     L+ L+L         L
Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265

Query: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486
           +P         Q   ++                +V EIL+ L Y  T  RL+  V+K  +
Sbjct: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKAKN 309

Query: 487 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 546
                     + +VK+ LL   G++MSK KT+++R  PNPV+ E  +F V    L D++L
Sbjct: 310 LIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSL 368

Query: 547 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
            ++V    S  R + +G + +G ++SG     HW +M  +  + V  WHA+
Sbjct: 369 RVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWHAV 418


>gi|47078261 double C2-like domains, alpha [Homo sapiens]
          Length = 400

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 80/333 (24%), Positives = 137/333 (41%), Gaps = 18/333 (5%)

Query: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI 332
           P+      +PED +   S       +D +     GTL+    YD     L  ++     +
Sbjct: 64  PAALLGATTPEDGAEVDS-------YDSDDATALGTLEFDLLYDRASCTLHCSILRAKGL 116

Query: 333 PTYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVR 389
              +  G     V L LLP   K  + KT  QR    PV+ E   ++ +  + I +  +R
Sbjct: 117 KPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLR 176

Query: 390 FRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSES 449
             +    ++   + +GE    L +L    K    + LE     +   S MS +    S  
Sbjct: 177 IAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLAS-PSSMSAALRGISCY 235

Query: 450 TSSCQSLEHGSV-----PEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTL 504
               +  E G         IL+ L Y++    L   +++ +H   +  N   + YVK T 
Sbjct: 236 LKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVK-TY 294

Query: 505 LNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGW 564
           L     + SK KT +++   NP + E F +++ L  L+  TL ++V++    K  + IG 
Sbjct: 295 LRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGG 354

Query: 565 ISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
           +SLG  + GE    HW++  +     + RWH L
Sbjct: 355 VSLGPGARGEAR-KHWSDCLQQPDAALERWHTL 386


>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
          Length = 421

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 80/301 (26%), Positives = 133/301 (44%), Gaps = 34/301 (11%)

Query: 302 PEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSI 361
           P+   G L  + +Y+ + ++LLV +     +   + T   S  V L LLP +++  ++  
Sbjct: 144 PDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC--SPLVKLYLLPDERRFLQSKT 201

Query: 362 QRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
           +R    P F E F F  V S+ I    ++F +Y V R +K +++G+ +F L    L G  
Sbjct: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDC 260

Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGS-VPEILIGLLYNATTGRLSA 479
              +  +                          +SLE  S   ++   L YN    RL+ 
Sbjct: 261 RRVIWRD-----------------------LEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297

Query: 480 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK-TSIRRGQPNPVYKETFVFQVAL 538
            V++    +        + +VK++L+N    +  KCK TS   G  NPVY ETF F+   
Sbjct: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNH--NKFVKCKKTSAVLGSINPVYNETFSFKADA 355

Query: 539 FQLSDVTLILSVYNKRSMKRKEMIGWISLG--LNSSGEEELNHWTEMKESKGQQVCRWHA 596
            +L   +L L+V       + + +G + +G  + + G  EL HW EM     + V RWHA
Sbjct: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRG-RELEHWDEMLSKPKELVKRWHA 414

Query: 597 L 597
           L
Sbjct: 415 L 415


>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
           sapiens]
          Length = 431

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 90/337 (26%), Positives = 142/337 (42%), Gaps = 42/337 (12%)

Query: 280 LSPEDMSAQGSSSQLPKPFDPEPEAK------YGTLDVTFDYDSQEQKLLVTVTAVTDIP 333
           L P   SA  S+ QL    DPEPE         GTL+ T  +++    L  T      + 
Sbjct: 109 LRPAAASAVRSAPQLQP--DPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 166

Query: 334 TYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGP-CPVFTETFKFNH----------VES 380
               +G     V   LLP   K  + +T   RG   PV+ ET  ++           + S
Sbjct: 167 PL-ASGSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRS 225

Query: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMS 440
           ++ G+ AV  R   V R  +   +GE    L KL      S  + LE          +  
Sbjct: 226 DLGGHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDICLE----------KRR 275

Query: 441 VSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYV 500
           + E+    +   C          +L+ L Y++  G L   V++ +H   + AN   + +V
Sbjct: 276 LEEVETEVAWEECG--------HVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFV 327

Query: 501 KLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKE 560
           +L L  + G++ SK KTS+ R   NP + E F +     +L+  TL++SV++       +
Sbjct: 328 RLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADD 386

Query: 561 MIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
            IG + LG ++SG E L HW E       ++  WH L
Sbjct: 387 FIGGVQLGSHASG-ERLRHWLECLGHSDHRLKLWHPL 422


>gi|94536846 synaptotagmin VIII [Homo sapiens]
          Length = 401

 Score = 79.3 bits (194), Expect = 9e-15
 Identities = 73/300 (24%), Positives = 134/300 (44%), Gaps = 37/300 (12%)

Query: 300 PEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKK-QRAK 358
           P    ++G L ++ ++D   Q++ V +    D+    R GG       V +  +   R +
Sbjct: 112 PGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL----RPGGTVDPYARVSVSTQAGHRHE 167

Query: 359 TSIQRGP-CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
           T + RG  CPVF ET  F+  ++E+ G   ++ +L+   R    + +GE    L  ++LQ
Sbjct: 168 TKVHRGTLCPVFDETCCFHIPQAELPGA-TLQVQLFNFKRFSGHEPLGELRLPLGTVDLQ 226

Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
             +    +L P                          + +   V E+   L Y  ++GRL
Sbjct: 227 HVLEHWYLLGPP------------------------AATQPEQVGELCFSLRYVPSSGRL 262

Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537
           +  V++    +   A      YVK+ L+ +  ++  K KT+ ++G   P + E F F V 
Sbjct: 263 TVVVLEARGLRPGLAE----PYVKVQLMLNQ-RKWKKRKTATKKGTAAPYFNEAFTFLVP 317

Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597
             Q+ +V L+L+V+++    R E +G + LG  +SG + L HW +M     + + + H L
Sbjct: 318 FSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376


>gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]
          Length = 451

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 50/181 (27%), Positives = 86/181 (47%), Gaps = 15/181 (8%)

Query: 417 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 476
           Q +  +P   +P +N     S  S+ E+    +   C          +L+ L Y++  G 
Sbjct: 277 QRQPRVPSAPDPKHN-----SARSMEEVETEVAWEECG--------HVLLSLCYSSQQGG 323

Query: 477 LSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQV 536
           L   V++ +H   + AN   + +V+L L  + G++ SK KTS+ R   NP + E F +  
Sbjct: 324 LLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSG 382

Query: 537 ALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHA 596
              +L+  TL++SV++       + IG + LG ++SG E L HW E       ++  WH 
Sbjct: 383 PREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASG-ERLRHWLECLGHSDHRLELWHP 441

Query: 597 L 597
           L
Sbjct: 442 L 442


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,933,573
Number of Sequences: 37866
Number of extensions: 1136586
Number of successful extensions: 2997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 2785
Number of HSP's gapped (non-prelim): 193
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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