BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] (600 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 1217 0.0 gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens] 1206 0.0 gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 1092 0.0 gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens] 1080 0.0 gi|123173752 synaptotagmin XIV-like [Homo sapiens] 436 e-122 gi|209447073 synaptotagmin I [Homo sapiens] 122 9e-28 gi|5032139 synaptotagmin I [Homo sapiens] 122 9e-28 gi|209447070 synaptotagmin I [Homo sapiens] 122 9e-28 gi|39752671 synaptotagmin X [Homo sapiens] 115 1e-25 gi|211059429 synaptotagmin II [Homo sapiens] 111 2e-24 gi|31543670 synaptotagmin II [Homo sapiens] 111 2e-24 gi|24308219 synaptotagmin IV [Homo sapiens] 110 3e-24 gi|216548478 synaptotagmin XI [Homo sapiens] 107 3e-23 gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 105 1e-22 gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 105 1e-22 gi|45504376 synaptotagmin VI [Homo sapiens] 105 1e-22 gi|38570146 synaptotagmin VII [Homo sapiens] 104 3e-22 gi|238550198 synaptotagmin III [Homo sapiens] 100 4e-21 gi|238550196 synaptotagmin III [Homo sapiens] 100 4e-21 gi|14150054 synaptotagmin III [Homo sapiens] 100 4e-21 gi|92859638 synaptotagmin V [Homo sapiens] 99 1e-20 gi|28376627 synaptotagmin IX [Homo sapiens] 94 5e-19 gi|6005997 double C2-like domains, beta [Homo sapiens] 92 2e-18 gi|40068038 B/K protein [Homo sapiens] 88 2e-17 gi|29366828 synaptotagmin XII [Homo sapiens] 88 3e-17 gi|47078261 double C2-like domains, alpha [Homo sapiens] 83 6e-16 gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 83 8e-16 gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 81 3e-15 gi|94536846 synaptotagmin VIII [Homo sapiens] 79 9e-15 gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 68 2e-11 >gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] Length = 600 Score = 1217 bits (3149), Expect = 0.0 Identities = 600/600 (100%), Positives = 600/600 (100%) Query: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ Sbjct: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60 Query: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI Sbjct: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120 Query: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE Sbjct: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180 Query: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS Sbjct: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240 Query: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP Sbjct: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300 Query: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS Sbjct: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360 Query: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM Sbjct: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420 Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480 Query: 481 VIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ 540 VIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ Sbjct: 481 VIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ 540 Query: 541 LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600 LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES Sbjct: 541 LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600 >gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens] Length = 619 Score = 1206 bits (3119), Expect = 0.0 Identities = 600/619 (96%), Positives = 600/619 (96%), Gaps = 19/619 (3%) Query: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ Sbjct: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60 Query: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI Sbjct: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120 Query: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE Sbjct: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180 Query: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS Sbjct: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240 Query: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP Sbjct: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300 Query: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS Sbjct: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360 Query: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM Sbjct: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420 Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480 Query: 481 VIKGSHFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRR 521 VIKGSHFKNLAANRPPN TYVKLTLLNSMGQEMSKCKTSIRR Sbjct: 481 VIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRR 540 Query: 522 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 581 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT Sbjct: 541 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 600 Query: 582 EMKESKGQQVCRWHALLES 600 EMKESKGQQVCRWHALLES Sbjct: 601 EMKESKGQQVCRWHALLES 619 >gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] Length = 555 Score = 1092 bits (2823), Expect = 0.0 Identities = 535/535 (100%), Positives = 535/535 (100%) Query: 66 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM Sbjct: 21 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80 Query: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS Sbjct: 81 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140 Query: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC Sbjct: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200 Query: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK Sbjct: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260 Query: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP Sbjct: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320 Query: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI Sbjct: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380 Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440 Query: 486 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 545 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT Sbjct: 441 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 500 Query: 546 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 600 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES Sbjct: 501 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES 555 >gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens] Length = 574 Score = 1080 bits (2793), Expect = 0.0 Identities = 535/554 (96%), Positives = 535/554 (96%), Gaps = 19/554 (3%) Query: 66 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM Sbjct: 21 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80 Query: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS Sbjct: 81 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140 Query: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC Sbjct: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200 Query: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK Sbjct: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260 Query: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP Sbjct: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320 Query: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI Sbjct: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380 Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440 Query: 486 HFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRRGQPNP 526 HFKNLAANRPPN TYVKLTLLNSMGQEMSKCKTSIRRGQPNP Sbjct: 441 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 500 Query: 527 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 586 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES Sbjct: 501 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 560 Query: 587 KGQQVCRWHALLES 600 KGQQVCRWHALLES Sbjct: 561 KGQQVCRWHALLES 574 >gi|123173752 synaptotagmin XIV-like [Homo sapiens] Length = 645 Score = 436 bits (1120), Expect = e-122 Identities = 244/485 (50%), Positives = 327/485 (67%), Gaps = 15/485 (3%) Query: 119 KIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSP-- 176 K NS+ D +E +SS+S++E + ++ ++SR+ + R + + + E + K+S Sbjct: 173 KQVNSFGDDEELSTSSDSDEEVIKQFEISVSRSQSFR-SVTSEKGKQTGLEQKPKFSRSL 231 Query: 177 LSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCE- 235 L+ DG A D QR R + L Y +D P S +P E GD+K Sbjct: 232 LTHGEDGTEVSACEDLDGASQR-RYSENLS------YGEDDHIPAHSQSPCERGDAKHHG 284 Query: 236 FSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP 295 SH +S S + +EGS E +F+++G+E+ +DS+++ SPE+ ++ Q+P Sbjct: 285 TSHQESSVVQSLRRQSTEGSLEMET-AFNSRGFEDSYATDSSSMWSPEEQDR--TNLQVP 341 Query: 296 KPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQ 355 EP +K G LDV F+Y + QKL VT+ +P +R+G NSWQVH+VLLP KK Sbjct: 342 SGVS-EPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPGKKH 400 Query: 356 RAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLN 415 R +T+IQRGP PVF E F +E + AVRFRLY +M +E+++GEK+FYL+ L+ Sbjct: 401 RGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLH 460 Query: 416 LQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTG 475 +G+M + ++LEP N S S +S S +S S+STSS QSL HG PE+L+GL YNATTG Sbjct: 461 PEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTG 520 Query: 476 RLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQ 535 RLS E+IKGSHF+NLA NR P+TY KL LLNS+GQEMS+CKTSIRRGQPNPVYKETFVFQ Sbjct: 521 RLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQ 580 Query: 536 VALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWH 595 VALFQLSDVTL++SVYN+R+MKRKEMIGWI+LG NSSGEEE +HW EMKE+KGQQ+CRWH Sbjct: 581 VALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWH 640 Query: 596 ALLES 600 LLES Sbjct: 641 TLLES 645 >gi|209447073 synaptotagmin I [Homo sapiens] Length = 422 Score = 122 bits (306), Expect = 9e-28 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%) Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358 +P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ + Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195 Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417 T + R PVF E F F SE+ G V +Y R K I+GE Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244 Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477 K+ + + D Q + E E + +I L Y T G+L Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290 Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537 + +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349 Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%) Query: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501 +E ++ + E + ++ L Y+ +L +I+ + L + YVK Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183 Query: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561 + LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++ Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240 Query: 562 IGWISLGLNSSGEEELNHWTE 582 IG + +N+ + H TE Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258 >gi|5032139 synaptotagmin I [Homo sapiens] Length = 422 Score = 122 bits (306), Expect = 9e-28 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%) Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358 +P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ + Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195 Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417 T + R PVF E F F SE+ G V +Y R K I+GE Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244 Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477 K+ + + D Q + E E + +I L Y T G+L Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290 Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537 + +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349 Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%) Query: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501 +E ++ + E + ++ L Y+ +L +I+ + L + YVK Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183 Query: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561 + LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++ Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240 Query: 562 IGWISLGLNSSGEEELNHWTE 582 IG + +N+ + H TE Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258 >gi|209447070 synaptotagmin I [Homo sapiens] Length = 422 Score = 122 bits (306), Expect = 9e-28 Identities = 83/300 (27%), Positives = 142/300 (47%), Gaps = 28/300 (9%) Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358 +P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ + Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195 Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417 T + R PVF E F F SE+ G V +Y R K I+GE Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244 Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477 K+ + + D Q + E E + +I L Y T G+L Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290 Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537 + +++ + K + + YVK+ L+ + G+ + K KT+I++ NP Y E+F F+V Sbjct: 291 TVVILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTIKKNTLNPYYNESFSFEVP 349 Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 Q+ V ++++V + + + + IG + +G NS+G EL HW++M + + + +WH L Sbjct: 350 FEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELRHWSDMLANPRRPIAQWHTL 408 Score = 47.4 bits (111), Expect = 4e-05 Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 6/141 (4%) Query: 442 SEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVK 501 +E ++ + E + ++ L Y+ +L +I+ + L + YVK Sbjct: 124 AETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVK 183 Query: 502 LTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEM 561 + LL + K +T + R NPV+ E F F+V +L TL+++VY+ + ++ Sbjct: 184 VFLLPD---KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 240 Query: 562 IGWISLGLNSSGEEELNHWTE 582 IG + +N+ + H TE Sbjct: 241 IGEFKVPMNT---VDFGHVTE 258 >gi|39752671 synaptotagmin X [Homo sapiens] Length = 523 Score = 115 bits (288), Expect = 1e-25 Identities = 81/297 (27%), Positives = 138/297 (46%), Gaps = 33/297 (11%) Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366 G L+ T YD + + L+V + D+P + TG + V + LLP +K++ +T + R Sbjct: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTL 292 Query: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425 P+F ETF+F V + + N + F +Y R + ++GE I Sbjct: 293 NPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL---------------- 335 Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSS---CQSLEHGSVPEILIGLLYNATTGRLSAEVI 482 D+ VS++S + C + E + EI+ L Y T GR++ VI Sbjct: 336 ----------DNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVI 385 Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542 K + K + + YVK++L+ G+ + K KT+ ++ NPVY E +F + + Sbjct: 386 KCRNLKAMDITGSSDPYVKVSLMCE-GRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVD 444 Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 V+L ++V + + E+IG GL++ G +HW EM + + WH LLE Sbjct: 445 QVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEMLAYHRKPITHWHPLLE 500 >gi|211059429 synaptotagmin II [Homo sapiens] Length = 419 Score = 111 bits (278), Expect = 2e-24 Identities = 78/300 (26%), Positives = 142/300 (47%), Gaps = 29/300 (9%) Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358 + EPE G L + DYD Q +L V V ++P + G + V + LLP KK++ + Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192 Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417 T + R P F ETF F V + +G + +Y R K I+GE Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240 Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477 + +P+ + D + E + E + +I L Y T G+L Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287 Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537 + +++ + K + + YVK+ L+ + G+ + K KT++++ NP + E+F F++ Sbjct: 288 TVCILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTVKKKTLNPYFNESFSFEIP 346 Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 Q+ V ++++V + + + E IG I +G N++G EL HW++M + + + +WH+L Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSL 405 >gi|31543670 synaptotagmin II [Homo sapiens] Length = 419 Score = 111 bits (278), Expect = 2e-24 Identities = 78/300 (26%), Positives = 142/300 (47%), Gaps = 29/300 (9%) Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358 + EPE G L + DYD Q +L V V ++P + G + V + LLP KK++ + Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192 Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417 T + R P F ETF F V + +G + +Y R K I+GE Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240 Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477 + +P+ + D + E + E + +I L Y T G+L Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287 Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537 + +++ + K + + YVK+ L+ + G+ + K KT++++ NP + E+F F++ Sbjct: 288 TVCILEAKNLKKMDVGGLSDPYVKIHLMQN-GKRLKKKKTTVKKKTLNPYFNESFSFEIP 346 Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 Q+ V ++++V + + + E IG I +G N++G EL HW++M + + + +WH+L Sbjct: 347 FEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELRHWSDMLANPRRPIAQWHSL 405 >gi|24308219 synaptotagmin IV [Homo sapiens] Length = 425 Score = 110 bits (276), Expect = 3e-24 Identities = 82/323 (25%), Positives = 146/323 (45%), Gaps = 35/323 (10%) Query: 280 LSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTG 339 +SPE + + S + E + K GTL + +Y+ + + +V + +P + Sbjct: 134 VSPESLKSSTSLTS------EEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187 Query: 340 GNSWQ-VHLVLLPIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHR 397 S + + +LP KK + KT + R P F ETF F + I A+ F + R Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247 Query: 398 MKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSL 456 ++ I+GE + L+ + L +GKM + + + + +S+ Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLM---------------NREIIKRNVRKSSGR---- 288 Query: 457 EHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK 516 E+LI L Y +TT L+ V+K H + + YVK+ L ++ + +SK K Sbjct: 289 -----GELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAK-KRISKKK 342 Query: 517 TSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEE 576 T +++ PN V+ E FVF + L D+++ V + R E+IG + LG + G Sbjct: 343 THVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGG 402 Query: 577 LNHWTEMKESKGQQVCRWHALLE 599 HW E+ + +Q+ +WH L + Sbjct: 403 -EHWKEICDYPRRQIAKWHVLCD 424 >gi|216548478 synaptotagmin XI [Homo sapiens] Length = 431 Score = 107 bits (267), Expect = 3e-23 Identities = 85/358 (23%), Positives = 160/358 (44%), Gaps = 36/358 (10%) Query: 246 SYNKCPSEGSTGHEIESFHNK-GYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEA 304 S +K P S+G I+ K Y E++ S T++ E S+ P PE + Sbjct: 105 SRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGE--------SKTTSPSSPEEDV 156 Query: 305 KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYN-RTGGNSWQVHLVLLPIKKQRAKTSIQR 363 G+L + DY+ ++ L+VT+ +P + +T G+ + + +LP K+ R KT + R Sbjct: 157 MLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLR 216 Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422 PVF ETF F + + + + F + R ++ ++GE + L + Sbjct: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV-------- 268 Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482 +PS ++ ++ + C S E+ + L Y R++ V+ Sbjct: 269 ----DPS------TGKVQLTRDIIKRNIQKCISRG-----ELQVSLSYQPVAQRMTVVVL 313 Query: 483 KGSHFKNL-AANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQL 541 K H + N YVK+ + + ++K KT +++ NP++ E+F++ + L Sbjct: 314 KARHLPKMDITGLSGNPYVKVNVYYGR-KRIAKKKTHVKKCTLNPIFNESFIYDIPTDLL 372 Query: 542 SDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 D+++ V + + E++G + LG +S HW E+ ES + V +WH+L E Sbjct: 373 PDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430 >gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] Length = 694 Score = 105 bits (262), Expect = 1e-22 Identities = 109/435 (25%), Positives = 177/435 (40%), Gaps = 27/435 (6%) Query: 182 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 237 D S A + N +Q R P + PP G+P S P G D K E + Sbjct: 259 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 318 Query: 238 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 295 P E TG + + G ED S + S +A ++ Q P Sbjct: 319 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 373 Query: 296 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 346 P + E EA G L+ + YD L T+ + + G V Sbjct: 374 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 433 Query: 347 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 402 L LLP K R KT ++ P++ ET ++ + E + +R + + + Sbjct: 434 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 492 Query: 403 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 462 +GE F L KL + + + LE + S M+ E + + Sbjct: 493 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 552 Query: 463 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRG 522 +IL+ L+Y+ G L +I+ H + AN + +VKL L MG++ +K KT I++ Sbjct: 553 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK-AKHKTQIKKK 611 Query: 523 QPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTE 582 NP + E F + + L+ +L +SV++ K + IG LG+++ G E L HW E Sbjct: 612 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ERLKHWYE 670 Query: 583 MKESKGQQVCRWHAL 597 ++K +++ RWH L Sbjct: 671 CLKNKDKKIERWHQL 685 >gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] Length = 690 Score = 105 bits (262), Expect = 1e-22 Identities = 109/435 (25%), Positives = 177/435 (40%), Gaps = 27/435 (6%) Query: 182 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 237 D S A + N +Q R P + PP G+P S P G D K E + Sbjct: 255 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 314 Query: 238 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 295 P E TG + + G ED S + S +A ++ Q P Sbjct: 315 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 369 Query: 296 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 346 P + E EA G L+ + YD L T+ + + G V Sbjct: 370 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 429 Query: 347 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 402 L LLP K R KT ++ P++ ET ++ + E + +R + + + Sbjct: 430 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 488 Query: 403 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 462 +GE F L KL + + + LE + S M+ E + + Sbjct: 489 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 548 Query: 463 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRG 522 +IL+ L+Y+ G L +I+ H + AN + +VKL L MG++ +K KT I++ Sbjct: 549 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK-AKHKTQIKKK 607 Query: 523 QPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTE 582 NP + E F + + L+ +L +SV++ K + IG LG+++ G E L HW E Sbjct: 608 TLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ERLKHWYE 666 Query: 583 MKESKGQQVCRWHAL 597 ++K +++ RWH L Sbjct: 667 CLKNKDKKIERWHQL 681 >gi|45504376 synaptotagmin VI [Homo sapiens] Length = 425 Score = 105 bits (262), Expect = 1e-22 Identities = 77/294 (26%), Positives = 139/294 (47%), Gaps = 27/294 (9%) Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366 G ++ + YD + + L+V + D+P + G + V + LLP +K + +T + R Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTL 205 Query: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425 P F E F F V E + + + ++ R + ++GE VI Sbjct: 206 NPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGE-----------------VI 247 Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485 L+ + S + S+ + ++ +S++ G EI+ L Y T GRL+ VIK Sbjct: 248 LDNLFEASDLSRETSIWK---DIQYATSESVDLG---EIMFSLCYLPTAGRLTLTVIKCR 301 Query: 486 HFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVT 545 + K + + YVK++LL G+ + K KT+I++ NPVY E +F + + V+ Sbjct: 302 NLKAMDITGYSDPYVKVSLLCD-GRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVS 360 Query: 546 LILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 L++SV + + E+IG +G+ + G +HW EM + + WH+L+E Sbjct: 361 LLISVMDYDRVGHNEIIGVCRVGITAEGLGR-DHWNEMLAYPRKPIAHWHSLVE 413 >gi|38570146 synaptotagmin VII [Homo sapiens] Length = 403 Score = 104 bits (259), Expect = 3e-22 Identities = 87/351 (24%), Positives = 149/351 (42%), Gaps = 31/351 (8%) Query: 248 NKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG 307 N P G T H+ ES V ++ S M + GS + + G Sbjct: 81 NTAPVPGQTPHD-ESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEED--EAHEGCSRENLG 137 Query: 308 TLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC- 366 + + Y+ QE L V + ++P + +G + V + LLP KK + +T ++R Sbjct: 138 RIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLN 197 Query: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426 P + ETF F E + + ++ R + +GE L K++L + L Sbjct: 198 PHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDL 257 Query: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486 +P CS+ + GS E+L+ L YN + + +IK + Sbjct: 258 KP-----------------CSDGS--------GSRGELLLSLCYNPSANSIIVNIIKARN 292 Query: 487 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 546 K + + YVK+ L+ + + K KT + NP++ E+F F + +L + T+ Sbjct: 293 LKAMDIGGTSDPYVKVWLMYK-DKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTI 351 Query: 547 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 I++V +K + R ++IG I L SG E+ HW +M Q V +WH L Sbjct: 352 IITVMDKDKLSRNDVIGKIYLSW-KSGPGEVKHWKDMIARPRQPVAQWHQL 401 >gi|238550198 synaptotagmin III [Homo sapiens] Length = 590 Score = 100 bits (249), Expect = 4e-21 Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%) Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363 A G + Y +L+V + D+P + G + V + LLP +K++ +T + R Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357 Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422 PVF ETF+F+ +E+ + F +Y R + ++G+ + L Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403 Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482 +LE + + E E + E+ L Y T GRL+ +I Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453 Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542 K S+ K + + YVK +L+ S G+ + K KTSI++ NP Y E VF VA + Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512 Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 +V L ++V + + E+IG +G +++ HW EM + + V WH L+E Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569 >gi|238550196 synaptotagmin III [Homo sapiens] Length = 590 Score = 100 bits (249), Expect = 4e-21 Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%) Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363 A G + Y +L+V + D+P + G + V + LLP +K++ +T + R Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357 Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422 PVF ETF+F+ +E+ + F +Y R + ++G+ + L Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403 Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482 +LE + + E E + E+ L Y T GRL+ +I Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453 Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542 K S+ K + + YVK +L+ S G+ + K KTSI++ NP Y E VF VA + Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512 Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 +V L ++V + + E+IG +G +++ HW EM + + V WH L+E Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569 >gi|14150054 synaptotagmin III [Homo sapiens] Length = 590 Score = 100 bits (249), Expect = 4e-21 Identities = 78/297 (26%), Positives = 132/297 (44%), Gaps = 26/297 (8%) Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363 A G + Y +L+V + D+P + G + V + LLP +K++ +T + R Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357 Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422 PVF ETF+F+ +E+ + F +Y R + ++G+ + L Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403 Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482 +LE + + E E + E+ L Y T GRL+ +I Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453 Query: 483 KGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLS 542 K S+ K + + YVK +L+ S G+ + K KTSI++ NP Y E VF VA + Sbjct: 454 KASNLKAMDLTGFSDPYVKASLI-SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVE 512 Query: 543 DVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 +V L ++V + + E+IG +G +++ HW EM + + V WH L+E Sbjct: 513 NVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569 >gi|92859638 synaptotagmin V [Homo sapiens] Length = 386 Score = 98.6 bits (244), Expect = 1e-20 Identities = 79/308 (25%), Positives = 135/308 (43%), Gaps = 32/308 (10%) Query: 295 PKPFDPEPEA----KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLL 350 P P P + + G L + DYD Q +LLV + + + G + V + LL Sbjct: 94 PAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLL 153 Query: 351 PIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF 409 P K++R +T + R P F ETF F E+ G V +Y R + +GE Sbjct: 154 PDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLV-MAVYDFDRFSRNDAIGEVRV 212 Query: 410 YLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLL 469 ++ ++L PV + E + +I L Sbjct: 213 PMSSVDL----GRPV--------------------QAWRELQAAPREEQEKLGDICFSLR 248 Query: 470 YNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYK 529 Y T G+L+ V++ + K + + YVK+ LL G+++ K KT+I++ NP Y Sbjct: 249 YVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQG-GKKVRKKKTTIKKNTLNPYYN 307 Query: 530 ETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQ 589 E F F+V Q+ V + L+V + + + E IG +++G ++G L HW +M + + Sbjct: 308 EAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRR 366 Query: 590 QVCRWHAL 597 + +WH+L Sbjct: 367 PIAQWHSL 374 Score = 44.3 bits (103), Expect = 3e-04 Identities = 31/134 (23%), Positives = 61/134 (45%), Gaps = 3/134 (2%) Query: 438 QMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPN 497 Q V E+ + S Q + + + L Y+ +G+L +++ L + Sbjct: 86 QPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSD 145 Query: 498 TYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMK 557 YV++ LL + + +T + R NP + ETF F+V +L L+++VY+ Sbjct: 146 PYVRVYLLPD---KRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFS 202 Query: 558 RKEMIGWISLGLNS 571 R + IG + + ++S Sbjct: 203 RNDAIGEVRVPMSS 216 >gi|28376627 synaptotagmin IX [Homo sapiens] Length = 491 Score = 93.6 bits (231), Expect = 5e-19 Identities = 74/300 (24%), Positives = 133/300 (44%), Gaps = 39/300 (13%) Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366 G L+ YD ++L+V + ++P + +G + V + LLP +K + +T + R Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281 Query: 367 -PVFTETFKF----NHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF--YLTKLNLQGK 419 PVF E F F N +E+ + F +Y R + ++G+ + +L + + Sbjct: 282 NPVFDEVFLFPVPYNDLEARKL-----HFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRE 336 Query: 420 MSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSA 479 L +E N ++ + E++ L Y T GRL+ Sbjct: 337 CILWKDIEYVTN-------------------------DNVDLGELMFSLCYLPTAGRLTI 371 Query: 480 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALF 539 +IK + K + + YVK++L+ G+ + K KTS +R NPVY E VF V Sbjct: 372 TIIKARNLKAMDITGASDPYVKVSLMCD-GRRLKKRKTSTKRNTLNPVYNEAIVFDVPPE 430 Query: 540 QLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599 + + L ++V + + E+IG +G N + +HW+EM + + WH+L+E Sbjct: 431 NIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489 >gi|6005997 double C2-like domains, beta [Homo sapiens] Length = 412 Score = 91.7 bits (226), Expect = 2e-18 Identities = 92/361 (25%), Positives = 156/361 (43%), Gaps = 35/361 (9%) Query: 251 PSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP-KPFDPEPEAK---- 305 P+ G S + +EDV A S S S ++ P KP + EP+A Sbjct: 62 PAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYES 121 Query: 306 -----YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLP----IKKQR 356 GTLD + YD + L T+T + + G V L LLP K R Sbjct: 122 DDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLR 181 Query: 357 AKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL 416 KT ++ P + ET + + E + +R + + + + +GE L KL Sbjct: 182 TKT-LRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKP 240 Query: 417 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 476 + + LE Q+ V + + +SLE ILI L Y++ Sbjct: 241 NHTKTFNICLE---------KQLPVDK-------TEDKSLEERG--RILISLKYSSQKQG 282 Query: 477 LSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQV 536 L +++ +H + AN + YVK T L + SK KT++++ NP + E F +++ Sbjct: 283 LLVGIVRCAHLAAMDANGYSDPYVK-TYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEI 341 Query: 537 ALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHA 596 L+ +L ++V++ K + IG + LG+++ G E L HW + ++K +++ RWH Sbjct: 342 KHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKG-ERLKHWFDCLKNKDKRIERWHT 400 Query: 597 L 597 L Sbjct: 401 L 401 >gi|40068038 B/K protein [Homo sapiens] Length = 474 Score = 88.2 bits (217), Expect = 2e-17 Identities = 84/338 (24%), Positives = 142/338 (42%), Gaps = 43/338 (12%) Query: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKY--GTLDVTFDYDSQEQKLLVTVTAVT 330 P D P S +S + D E +KY G L + YD L V V Sbjct: 150 PDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEAR 209 Query: 331 DIPT-YNRTGGNSWQVH------LVLLPIKKQRAKTSIQRGPC-PVFTE--TFKFNHVES 380 D+P + G H + LLP +K +T ++R PVF E TF+ +E+ Sbjct: 210 DLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEA 269 Query: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQM 439 + + + + + ++G+ L +++L +G ++ S N Sbjct: 270 Q---RRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNE------- 319 Query: 440 SVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTY 499 +E G E+L+ L Y + GRL+ +VI+ ++ + + Sbjct: 320 ----------------VELG---ELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPF 360 Query: 500 VKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRK 559 VK+ L++ + +K KTS RG +P Y E+F F+V +L + +L+ +V+ Sbjct: 361 VKIQLVHGLKLVKTK-KTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSN 419 Query: 560 EMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 + IG I +G SSG E NHW M + V +WH+L Sbjct: 420 DFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457 >gi|29366828 synaptotagmin XII [Homo sapiens] Length = 421 Score = 87.8 bits (216), Expect = 3e-17 Identities = 72/291 (24%), Positives = 129/291 (44%), Gaps = 26/291 (8%) Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366 G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 Query: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426 +F + ++ + ++RF ++G+ ++ G L+ L+L L Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265 Query: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486 +P Q ++ +V EIL+ L Y T RL+ V+K + Sbjct: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKAKN 309 Query: 487 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 546 + +VK+ LL G++MSK KT+++R PNPV+ E +F V L D++L Sbjct: 310 LIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSL 368 Query: 547 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 ++V S R + +G + +G ++SG HW +M + + V WHA+ Sbjct: 369 RVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWHAV 418 >gi|47078261 double C2-like domains, alpha [Homo sapiens] Length = 400 Score = 83.2 bits (204), Expect = 6e-16 Identities = 80/333 (24%), Positives = 137/333 (41%), Gaps = 18/333 (5%) Query: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI 332 P+ +PED + S +D + GTL+ YD L ++ + Sbjct: 64 PAALLGATTPEDGAEVDS-------YDSDDATALGTLEFDLLYDRASCTLHCSILRAKGL 116 Query: 333 PTYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVR 389 + G V L LLP K + KT QR PV+ E ++ + + I + +R Sbjct: 117 KPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLR 176 Query: 390 FRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSES 449 + ++ + +GE L +L K + LE + S MS + S Sbjct: 177 IAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLAS-PSSMSAALRGISCY 235 Query: 450 TSSCQSLEHGSV-----PEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTL 504 + E G IL+ L Y++ L +++ +H + N + YVK T Sbjct: 236 LKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVK-TY 294 Query: 505 LNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGW 564 L + SK KT +++ NP + E F +++ L L+ TL ++V++ K + IG Sbjct: 295 LRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGG 354 Query: 565 ISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 +SLG + GE HW++ + + RWH L Sbjct: 355 VSLGPGARGEAR-KHWSDCLQQPDAALERWHTL 386 >gi|31881675 synaptotagmin XV isoform a [Homo sapiens] Length = 421 Score = 82.8 bits (203), Expect = 8e-16 Identities = 80/301 (26%), Positives = 133/301 (44%), Gaps = 34/301 (11%) Query: 302 PEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSI 361 P+ G L + +Y+ + ++LLV + + + T S V L LLP +++ ++ Sbjct: 144 PDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC--SPLVKLYLLPDERRFLQSKT 201 Query: 362 QRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420 +R P F E F F V S+ I ++F +Y V R +K +++G+ +F L L G Sbjct: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDC 260 Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGS-VPEILIGLLYNATTGRLSA 479 + + +SLE S ++ L YN RL+ Sbjct: 261 RRVIWRD-----------------------LEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297 Query: 480 EVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCK-TSIRRGQPNPVYKETFVFQVAL 538 V++ + + +VK++L+N + KCK TS G NPVY ETF F+ Sbjct: 298 VVLRAKGLRLQEDRGIVSVFVKVSLMNH--NKFVKCKKTSAVLGSINPVYNETFSFKADA 355 Query: 539 FQLSDVTLILSVYNKRSMKRKEMIGWISLG--LNSSGEEELNHWTEMKESKGQQVCRWHA 596 +L +L L+V + + +G + +G + + G EL HW EM + V RWHA Sbjct: 356 TELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRG-RELEHWDEMLSKPKELVKRWHA 414 Query: 597 L 597 L Sbjct: 415 L 415 >gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sapiens] Length = 431 Score = 80.9 bits (198), Expect = 3e-15 Identities = 90/337 (26%), Positives = 142/337 (42%), Gaps = 42/337 (12%) Query: 280 LSPEDMSAQGSSSQLPKPFDPEPEAK------YGTLDVTFDYDSQEQKLLVTVTAVTDIP 333 L P SA S+ QL DPEPE GTL+ T +++ L T + Sbjct: 109 LRPAAASAVRSAPQLQP--DPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 166 Query: 334 TYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGP-CPVFTETFKFNH----------VES 380 +G V LLP K + +T RG PV+ ET ++ + S Sbjct: 167 PL-ASGSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRS 225 Query: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMS 440 ++ G+ AV R V R + +GE L KL S + LE + Sbjct: 226 DLGGHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDICLE----------KRR 275 Query: 441 VSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYV 500 + E+ + C +L+ L Y++ G L V++ +H + AN + +V Sbjct: 276 LEEVETEVAWEECG--------HVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPFV 327 Query: 501 KLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKE 560 +L L + G++ SK KTS+ R NP + E F + +L+ TL++SV++ + Sbjct: 328 RLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADD 386 Query: 561 MIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 IG + LG ++SG E L HW E ++ WH L Sbjct: 387 FIGGVQLGSHASG-ERLRHWLECLGHSDHRLKLWHPL 422 >gi|94536846 synaptotagmin VIII [Homo sapiens] Length = 401 Score = 79.3 bits (194), Expect = 9e-15 Identities = 73/300 (24%), Positives = 134/300 (44%), Gaps = 37/300 (12%) Query: 300 PEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKK-QRAK 358 P ++G L ++ ++D Q++ V + D+ R GG V + + R + Sbjct: 112 PGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL----RPGGTVDPYARVSVSTQAGHRHE 167 Query: 359 TSIQRGP-CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417 T + RG CPVF ET F+ ++E+ G ++ +L+ R + +GE L ++LQ Sbjct: 168 TKVHRGTLCPVFDETCCFHIPQAELPGA-TLQVQLFNFKRFSGHEPLGELRLPLGTVDLQ 226 Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477 + +L P + + V E+ L Y ++GRL Sbjct: 227 HVLEHWYLLGPP------------------------AATQPEQVGELCFSLRYVPSSGRL 262 Query: 478 SAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVA 537 + V++ + A YVK+ L+ + ++ K KT+ ++G P + E F F V Sbjct: 263 TVVVLEARGLRPGLAE----PYVKVQLMLNQ-RKWKKRKTATKKGTAAPYFNEAFTFLVP 317 Query: 538 LFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 Q+ +V L+L+V+++ R E +G + LG +SG + L HW +M + + + H L Sbjct: 318 FSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASG-QPLQHWADMLAHARRPIAQRHPL 376 >gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] Length = 451 Score = 68.2 bits (165), Expect = 2e-11 Identities = 50/181 (27%), Positives = 86/181 (47%), Gaps = 15/181 (8%) Query: 417 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 476 Q + +P +P +N S S+ E+ + C +L+ L Y++ G Sbjct: 277 QRQPRVPSAPDPKHN-----SARSMEEVETEVAWEECG--------HVLLSLCYSSQQGG 323 Query: 477 LSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQV 536 L V++ +H + AN + +V+L L + G++ SK KTS+ R NP + E F + Sbjct: 324 LLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSG 382 Query: 537 ALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHA 596 +L+ TL++SV++ + IG + LG ++SG E L HW E ++ WH Sbjct: 383 PREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASG-ERLRHWLECLGHSDHRLELWHP 441 Query: 597 L 597 L Sbjct: 442 L 442 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.130 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 23,933,573 Number of Sequences: 37866 Number of extensions: 1136586 Number of successful extensions: 2997 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 44 Number of HSP's that attempted gapping in prelim test: 2785 Number of HSP's gapped (non-prelim): 193 length of query: 600 length of database: 18,247,518 effective HSP length: 108 effective length of query: 492 effective length of database: 14,157,990 effective search space: 6965731080 effective search space used: 6965731080 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.