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Search of human proteins with 226342955
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]
(619 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens] 1258 0.0
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 1206 0.0
gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens] 1132 0.0
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 1080 0.0
gi|123173752 synaptotagmin XIV-like [Homo sapiens] 426 e-119
gi|209447073 synaptotagmin I [Homo sapiens] 117 4e-26
gi|5032139 synaptotagmin I [Homo sapiens] 117 4e-26
gi|209447070 synaptotagmin I [Homo sapiens] 117 4e-26
gi|39752671 synaptotagmin X [Homo sapiens] 106 6e-23
gi|211059429 synaptotagmin II [Homo sapiens] 106 7e-23
gi|31543670 synaptotagmin II [Homo sapiens] 106 7e-23
gi|24308219 synaptotagmin IV [Homo sapiens] 105 1e-22
gi|216548478 synaptotagmin XI [Homo sapiens] 99 1e-20
gi|38570146 synaptotagmin VII [Homo sapiens] 98 3e-20
gi|45504376 synaptotagmin VI [Homo sapiens] 97 3e-20
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 97 6e-20
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 97 6e-20
gi|238550198 synaptotagmin III [Homo sapiens] 93 6e-19
gi|238550196 synaptotagmin III [Homo sapiens] 93 6e-19
gi|14150054 synaptotagmin III [Homo sapiens] 93 6e-19
gi|92859638 synaptotagmin V [Homo sapiens] 93 6e-19
gi|28376627 synaptotagmin IX [Homo sapiens] 85 2e-16
gi|29366828 synaptotagmin XII [Homo sapiens] 84 3e-16
gi|6005997 double C2-like domains, beta [Homo sapiens] 83 9e-16
gi|40068038 B/K protein [Homo sapiens] 81 2e-15
gi|47078261 double C2-like domains, alpha [Homo sapiens] 77 5e-14
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 75 2e-13
gi|94536846 synaptotagmin VIII [Homo sapiens] 73 7e-13
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 72 2e-12
gi|24308233 synaptotagmin XIII [Homo sapiens] 60 5e-09
>gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens]
Length = 619
Score = 1258 bits (3255), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60
MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ
Sbjct: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60
Query: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120
VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI
Sbjct: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120
Query: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180
YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE
Sbjct: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180
Query: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240
YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS
Sbjct: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240
Query: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300
NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP
Sbjct: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300
Query: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360
EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS
Sbjct: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360
Query: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM
Sbjct: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480
SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE
Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480
Query: 481 VIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRR 540
VIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRR
Sbjct: 481 VIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRR 540
Query: 541 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 600
GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT
Sbjct: 541 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 600
Query: 601 EMKESKGQQVCRWHALLES 619
EMKESKGQQVCRWHALLES
Sbjct: 601 EMKESKGQQVCRWHALLES 619
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 1206 bits (3119), Expect = 0.0
Identities = 600/619 (96%), Positives = 600/619 (96%), Gaps = 19/619 (3%)
Query: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60
MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ
Sbjct: 1 MASASWRLKVEREPVEYMNLSVLEKIGYFSVARLEYSGTILAHCNFRLLGSNDSSASASQ 60
Query: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120
VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI
Sbjct: 61 VTGTTVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKI 120
Query: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180
YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE
Sbjct: 121 YNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAE 180
Query: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240
YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS
Sbjct: 181 YDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCS 240
Query: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300
NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP
Sbjct: 241 NSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDP 300
Query: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360
EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS
Sbjct: 301 EPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTS 360
Query: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM
Sbjct: 361 IQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480
SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE
Sbjct: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAE 480
Query: 481 VIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRR 540
VIKGSHFKNLAANRPPN TYVKLTLLNSMGQEMSKCKTSIRR
Sbjct: 481 VIKGSHFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRR 521
Query: 541 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 600
GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT
Sbjct: 522 GQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWT 581
Query: 601 EMKESKGQQVCRWHALLES 619
EMKESKGQQVCRWHALLES
Sbjct: 582 EMKESKGQQVCRWHALLES 600
>gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens]
Length = 574
Score = 1132 bits (2929), Expect = 0.0
Identities = 554/554 (100%), Positives = 554/554 (100%)
Query: 66 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125
VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM
Sbjct: 21 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80
Query: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185
DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS
Sbjct: 81 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140
Query: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245
SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC
Sbjct: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200
Query: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305
SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK
Sbjct: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260
Query: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365
YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP
Sbjct: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320
Query: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI
Sbjct: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS
Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440
Query: 486 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 545
HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP
Sbjct: 441 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 500
Query: 546 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 605
VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES
Sbjct: 501 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 560
Query: 606 KGQQVCRWHALLES 619
KGQQVCRWHALLES
Sbjct: 561 KGQQVCRWHALLES 574
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 1080 bits (2793), Expect = 0.0
Identities = 535/554 (96%), Positives = 535/554 (96%), Gaps = 19/554 (3%)
Query: 66 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 125
VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM
Sbjct: 21 VSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYM 80
Query: 126 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 185
DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS
Sbjct: 81 DKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYS 140
Query: 186 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 245
SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC
Sbjct: 141 SEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRC 200
Query: 246 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 305
SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK
Sbjct: 201 SYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAK 260
Query: 306 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 365
YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP
Sbjct: 261 YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGP 320
Query: 366 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI
Sbjct: 321 CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 380
Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS
Sbjct: 381 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 440
Query: 486 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 545
HFKNLAANRPPN TYVKLTLLNSMGQEMSKCKTSIRRGQPNP
Sbjct: 441 HFKNLAANRPPN-------------------TYVKLTLLNSMGQEMSKCKTSIRRGQPNP 481
Query: 546 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 605
VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES
Sbjct: 482 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 541
Query: 606 KGQQVCRWHALLES 619
KGQQVCRWHALLES
Sbjct: 542 KGQQVCRWHALLES 555
>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
Length = 645
Score = 426 bits (1095), Expect = e-119
Identities = 245/504 (48%), Positives = 327/504 (64%), Gaps = 34/504 (6%)
Query: 119 KIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSP-- 176
K NS+ D +E +SS+S++E + ++ ++SR+ + R + + + E + K+S
Sbjct: 173 KQVNSFGDDEELSTSSDSDEEVIKQFEISVSRSQSFR-SVTSEKGKQTGLEQKPKFSRSL 231
Query: 177 LSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCE- 235
L+ DG A D QR R + L Y +D P S +P E GD+K
Sbjct: 232 LTHGEDGTEVSACEDLDGASQR-RYSENLS------YGEDDHIPAHSQSPCERGDAKHHG 284
Query: 236 FSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP 295
SH +S S + +EGS E +F+++G+E+ +DS+++ SPE+ ++ Q+P
Sbjct: 285 TSHQESSVVQSLRRQSTEGSLEMET-AFNSRGFEDSYATDSSSMWSPEEQDR--TNLQVP 341
Query: 296 KPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQ 355
EP +K G LDV F+Y + QKL VT+ +P +R+G NSWQVH+VLLP KK
Sbjct: 342 SGVS-EPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPGKKH 400
Query: 356 RAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLN 415
R +T+IQRGP PVF E F +E + AVRFRLY +M +E+++GEK+FYL+ L+
Sbjct: 401 RGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLH 460
Query: 416 LQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTG 475
+G+M + ++LEP N S S +S S +S S+STSS QSL HG PE+L+GL YNATTG
Sbjct: 461 PEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTG 520
Query: 476 RLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCK 535
RLS E+IKGSHF+NLA NR P DTY KL LLNS+GQEMS+CK
Sbjct: 521 RLSVEMIKGSHFRNLAVNRAP-------------------DTYGKLFLLNSVGQEMSRCK 561
Query: 536 TSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEE 595
TSIRRGQPNPVYKETFVFQVALFQLSDVTL++SVYN+R+MKRKEMIGWI+LG NSSGEEE
Sbjct: 562 TSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEE 621
Query: 596 LNHWTEMKESKGQQVCRWHALLES 619
+HW EMKE+KGQQ+CRWH LLES
Sbjct: 622 QDHWEEMKETKGQQICRWHTLLES 645
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 117 bits (292), Expect = 4e-26
Identities = 86/319 (26%), Positives = 146/319 (45%), Gaps = 47/319 (14%)
Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
Query: 478 SAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTS 537
+ +++ + K + +GG + D YVK+ L+ + G+ + K KT+
Sbjct: 291 TVVILEAKNLKKMD---------------VGG----LSDPYVKIHLMQN-GKRLKKKKTT 330
Query: 538 IRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELN 597
I++ NP Y E+F F+V Q+ V ++++V + + + + IG + +G NS+G EL
Sbjct: 331 IKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELR 389
Query: 598 HWTEMKESKGQQVCRWHAL 616
HW++M + + + +WH L
Sbjct: 390 HWSDMLANPRRPIAQWHTL 408
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 117 bits (292), Expect = 4e-26
Identities = 86/319 (26%), Positives = 146/319 (45%), Gaps = 47/319 (14%)
Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
Query: 478 SAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTS 537
+ +++ + K + +GG + D YVK+ L+ + G+ + K KT+
Sbjct: 291 TVVILEAKNLKKMD---------------VGG----LSDPYVKIHLMQN-GKRLKKKKTT 330
Query: 538 IRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELN 597
I++ NP Y E+F F+V Q+ V ++++V + + + + IG + +G NS+G EL
Sbjct: 331 IKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELR 389
Query: 598 HWTEMKESKGQQVCRWHAL 616
HW++M + + + +WH L
Sbjct: 390 HWSDMLANPRRPIAQWHTL 408
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 117 bits (292), Expect = 4e-26
Identities = 86/319 (26%), Positives = 146/319 (45%), Gaps = 47/319 (14%)
Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
+P+ E K G L + DYD Q +LLV + ++P + G + V + LLP KK++ +
Sbjct: 136 EPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFE 195
Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
T + R PVF E F F SE+ G V +Y R K I+GE
Sbjct: 196 TKVHRKTLNPVFNEQFTFKVPYSELGGKTLV-MAVYDFDRFSKHDIIGEF---------- 244
Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
K+ + + D Q + E E + +I L Y T G+L
Sbjct: 245 -KVPMNTVDFGHVTEEWRDLQSAEKE-------------EQEKLGDICFSLRYVPTAGKL 290
Query: 478 SAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTS 537
+ +++ + K + +GG + D YVK+ L+ + G+ + K KT+
Sbjct: 291 TVVILEAKNLKKMD---------------VGG----LSDPYVKIHLMQN-GKRLKKKKTT 330
Query: 538 IRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELN 597
I++ NP Y E+F F+V Q+ V ++++V + + + + IG + +G NS+G EL
Sbjct: 331 IKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTG-AELR 389
Query: 598 HWTEMKESKGQQVCRWHAL 616
HW++M + + + +WH L
Sbjct: 390 HWSDMLANPRRPIAQWHTL 408
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 106 bits (265), Expect = 6e-23
Identities = 83/316 (26%), Positives = 140/316 (44%), Gaps = 52/316 (16%)
Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
G L+ T YD + + L+V + D+P + TG + V + LLP +K++ +T + R
Sbjct: 233 GKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTL 292
Query: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
P+F ETF+F V + + N + F +Y R + ++GE I
Sbjct: 293 NPLFDETFQFP-VAYDQLSNRKLHFSVYDFDRFSRHDMIGEVIL---------------- 335
Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSS---CQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
D+ VS++S + C + E + EI+ L Y T GR++ VI
Sbjct: 336 ----------DNLFEVSDLSREATVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVI 385
Query: 483 KGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQ 542
K + K + + G D YVK++L+ G+ + K KT+ ++
Sbjct: 386 KCRNLKAM--------------DITGSS-----DPYVKVSLMCE-GRRLKKRKTTTKKNT 425
Query: 543 PNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEM 602
NPVY E +F + + V+L ++V + + E+IG GL++ G +HW EM
Sbjct: 426 LNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGR-DHWNEM 484
Query: 603 KESKGQQVCRWHALLE 618
+ + WH LLE
Sbjct: 485 LAYHRKPITHWHPLLE 500
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 106 bits (264), Expect = 7e-23
Identities = 81/319 (25%), Positives = 146/319 (45%), Gaps = 48/319 (15%)
Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
+ EPE G L + DYD Q +L V V ++P + G + V + LLP KK++ +
Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192
Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
T + R P F ETF F V + +G + +Y R K I+GE
Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240
Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
+ +P+ + D + E + E + +I L Y T G+L
Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287
Query: 478 SAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTS 537
+ +++ + K + +GG + D YVK+ L+ + G+ + K KT+
Sbjct: 288 TVCILEAKNLKKMD---------------VGG----LSDPYVKIHLMQN-GKRLKKKKTT 327
Query: 538 IRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELN 597
+++ NP + E+F F++ Q+ V ++++V + + + E IG I +G N++G EL
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELR 386
Query: 598 HWTEMKESKGQQVCRWHAL 616
HW++M + + + +WH+L
Sbjct: 387 HWSDMLANPRRPIAQWHSL 405
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 106 bits (264), Expect = 7e-23
Identities = 81/319 (25%), Positives = 146/319 (45%), Gaps = 48/319 (15%)
Query: 299 DPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAK 358
+ EPE G L + DYD Q +L V V ++P + G + V + LLP KK++ +
Sbjct: 134 EKEPE-NLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYE 192
Query: 359 TSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
T + R P F ETF F V + +G + +Y R K I+GE
Sbjct: 193 TKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGE----------- 240
Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
+ +P+ + D + E + E + +I L Y T G+L
Sbjct: 241 --VKVPM--------NTVDLGQPIEEW---RDLQGGEKEEPEKLGDICTSLRYVPTAGKL 287
Query: 478 SAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTS 537
+ +++ + K + +GG + D YVK+ L+ + G+ + K KT+
Sbjct: 288 TVCILEAKNLKKMD---------------VGG----LSDPYVKIHLMQN-GKRLKKKKTT 327
Query: 538 IRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELN 597
+++ NP + E+F F++ Q+ V ++++V + + + E IG I +G N++G EL
Sbjct: 328 VKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATG-TELR 386
Query: 598 HWTEMKESKGQQVCRWHAL 616
HW++M + + + +WH+L
Sbjct: 387 HWSDMLANPRRPIAQWHSL 405
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 105 bits (262), Expect = 1e-22
Identities = 85/342 (24%), Positives = 149/342 (43%), Gaps = 54/342 (15%)
Query: 280 LSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTG 339
+SPE + + S + E + K GTL + +Y+ + + +V + +P +
Sbjct: 134 VSPESLKSSTSLTS------EEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQS 187
Query: 340 GNSWQ-VHLVLLPIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHR 397
S + + +LP KK + KT + R P F ETF F + I A+ F + R
Sbjct: 188 MTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDR 247
Query: 398 MKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSL 456
++ I+GE + L+ + L +GKM + + + + +S+
Sbjct: 248 FSRDDIIGEVLIPLSGIELSEGKMLM---------------NREIIKRNVRKSSGR---- 288
Query: 457 EHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRD 516
E+LI L Y +TT L+ V+K +HL V + D
Sbjct: 289 -----GELLISLCYQSTTNTLTVVVLKA-------------------RHLPKSDVSGLSD 324
Query: 517 TYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMK 576
YVK+ L ++ + +SK KT +++ PN V+ E FVF + L D+++ V +
Sbjct: 325 PYVKVNLYHAK-KRISKKKTHVKKCTPNAVFNELFVFDIPCEGLEDISVEFLVLDSERGS 383
Query: 577 RKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 618
R E+IG + LG + G HW E+ + +Q+ +WH L +
Sbjct: 384 RNEVIGQLVLGAAAEGTGG-EHWKEICDYPRRQIAKWHVLCD 424
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 99.0 bits (245), Expect = 1e-20
Identities = 84/376 (22%), Positives = 160/376 (42%), Gaps = 53/376 (14%)
Query: 246 SYNKCPSEGSTGHEIESFHNK-GYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEA 304
S +K P S+G I+ K Y E++ S T++ E S+ P PE +
Sbjct: 105 SRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGE--------SKTTSPSSPEEDV 156
Query: 305 KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYN-RTGGNSWQVHLVLLPIKKQRAKTSIQR 363
G+L + DY+ ++ L+VT+ +P + +T G+ + + +LP K+ R KT + R
Sbjct: 157 MLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLR 216
Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
PVF ETF F + + + + F + R ++ ++GE + L +
Sbjct: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV-------- 268
Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
+PS ++ ++ + C S E+ + L Y R++ V+
Sbjct: 269 ----DPS------TGKVQLTRDIIKRNIQKCISRG-----ELQVSLSYQPVAQRMTVVVL 313
Query: 483 KGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQ 542
K H + + G Y+ + Y + ++K KT +++
Sbjct: 314 KARHLPKMDITG------------LSGNPYVKVNVYYGR-------KRIAKKKTHVKKCT 354
Query: 543 PNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEM 602
NP++ E+F++ + L D+++ V + + E++G + LG +S HW E+
Sbjct: 355 LNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREV 414
Query: 603 KESKGQQVCRWHALLE 618
ES + V +WH+L E
Sbjct: 415 CESPRKPVAKWHSLSE 430
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 97.8 bits (242), Expect = 3e-20
Identities = 91/370 (24%), Positives = 152/370 (41%), Gaps = 50/370 (13%)
Query: 248 NKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYG 307
N P G T H+ ES V ++ S M + GS + + G
Sbjct: 81 NTAPVPGQTPHD-ESDRRTEPRSSVSDLVNSLTSEMLMLSPGSEED--EAHEGCSRENLG 137
Query: 308 TLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC- 366
+ + Y+ QE L V + ++P + +G + V + LLP KK + +T ++R
Sbjct: 138 RIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLN 197
Query: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426
P + ETF F E + + ++ R + +GE L K++L + L
Sbjct: 198 PHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDL 257
Query: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486
+P CS+ + GS E+L+ L YN + + +IK +
Sbjct: 258 KP-----------------CSDGS--------GSRGELLLSLCYNPSANSIIVNIIKARN 292
Query: 487 FKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPV 546
K + IGG D YVK+ L+ + + K KT + NP+
Sbjct: 293 LKAMD---------------IGGT----SDPYVKVWLMYK-DKRVEKKKTVTMKRNLNPI 332
Query: 547 YKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK 606
+ E+F F + +L + T+I++V +K + R ++IG I L SG E+ HW +M
Sbjct: 333 FNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSW-KSGPGEVKHWKDMIARP 391
Query: 607 GQQVCRWHAL 616
Q V +WH L
Sbjct: 392 RQPVAQWHQL 401
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 97.4 bits (241), Expect = 3e-20
Identities = 78/313 (24%), Positives = 140/313 (44%), Gaps = 46/313 (14%)
Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
G ++ + YD + + L+V + D+P + G + V + LLP +K + +T + R
Sbjct: 146 GKINFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTL 205
Query: 367 -PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVI 425
P F E F F V E + + + ++ R + ++GE VI
Sbjct: 206 NPTFDENFHFP-VPYEELADRKLHLSVFDFDRFSRHDMIGE-----------------VI 247
Query: 426 LEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGS 485
L+ + S + S+ + ++ +S++ G EI+ L Y T GRL+ VIK
Sbjct: 248 LDNLFEASDLSRETSIWK---DIQYATSESVDLG---EIMFSLCYLPTAGRLTLTVIKCR 301
Query: 486 HFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNP 545
+ K + + D YVK++LL G+ + K KT+I++ NP
Sbjct: 302 NLKAM-------------------DITGYSDPYVKVSLLCD-GRRLKKKKTTIKKNTLNP 341
Query: 546 VYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKES 605
VY E +F + + V+L++SV + + E+IG +G+ + G +HW EM
Sbjct: 342 VYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGR-DHWNEMLAY 400
Query: 606 KGQQVCRWHALLE 618
+ + WH+L+E
Sbjct: 401 PRKPIAHWHSLVE 413
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 96.7 bits (239), Expect = 6e-20
Identities = 110/454 (24%), Positives = 177/454 (38%), Gaps = 46/454 (10%)
Query: 182 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 237
D S A + N +Q R P + PP G+P S P G D K E +
Sbjct: 259 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 318
Query: 238 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 295
P E TG + + G ED S + S +A ++ Q P
Sbjct: 319 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 373
Query: 296 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 346
P + E EA G L+ + YD L T+ + + G V
Sbjct: 374 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 433
Query: 347 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 402
L LLP K R KT ++ P++ ET ++ + E + +R + + +
Sbjct: 434 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 492
Query: 403 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 462
+GE F L KL + + + LE + S M+ E + +
Sbjct: 493 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 552
Query: 463 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLT 522
+IL+ L+Y+ G L +I+ H + AN D +VKL
Sbjct: 553 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANG-------------------YSDPFVKLW 593
Query: 523 LLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIG 582
L MG++ +K KT I++ NP + E F + + L+ +L +SV++ K + IG
Sbjct: 594 LKPDMGKK-AKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 652
Query: 583 WISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 616
LG+++ G E L HW E ++K +++ RWH L
Sbjct: 653 GCQLGISAKG-ERLKHWYECLKNKDKKIERWHQL 685
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 96.7 bits (239), Expect = 6e-20
Identities = 110/454 (24%), Positives = 177/454 (38%), Gaps = 46/454 (10%)
Query: 182 DGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCT-PSEIG---DSKCEFS 237
D S A + N +Q R P + PP G+P S P G D K E +
Sbjct: 255 DSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVA 314
Query: 238 HCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQ--GSSSQLP 295
P E TG + + G ED S + S +A ++ Q P
Sbjct: 315 PSDPGTTAP----PREERTGG-VGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPP 369
Query: 296 KPFDPEPEAK---------YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVH 346
P + E EA G L+ + YD L T+ + + G V
Sbjct: 370 PPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVK 429
Query: 347 LVLLP----IKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEK 402
L LLP K R KT ++ P++ ET ++ + E + +R + + +
Sbjct: 430 LHLLPGASKSNKLRTKT-LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNE 488
Query: 403 IVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVP 462
+GE F L KL + + + LE + S M+ E + +
Sbjct: 489 FIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERG 548
Query: 463 EILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLT 522
+IL+ L+Y+ G L +I+ H + AN D +VKL
Sbjct: 549 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANG-------------------YSDPFVKLW 589
Query: 523 LLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIG 582
L MG++ +K KT I++ NP + E F + + L+ +L +SV++ K + IG
Sbjct: 590 LKPDMGKK-AKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
Query: 583 WISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 616
LG+++ G E L HW E ++K +++ RWH L
Sbjct: 649 GCQLGISAKG-ERLKHWYECLKNKDKKIERWHQL 681
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 93.2 bits (230), Expect = 6e-19
Identities = 81/316 (25%), Positives = 134/316 (42%), Gaps = 45/316 (14%)
Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363
A G + Y +L+V + D+P + G + V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357
Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
PVF ETF+F+ +E+ + F +Y R + ++G+ + L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403
Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
+LE + + E E + E+ L Y T GRL+ +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453
Query: 483 KGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQ 542
K S+ K + L G D YVK +L+ S G+ + K KTSI++
Sbjct: 454 KASNLKAM--------------DLTG-----FSDPYVKASLI-SEGRRLKKRKTSIKKNT 493
Query: 543 PNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEM 602
NP Y E VF VA + +V L ++V + + E+IG +G +++ HW EM
Sbjct: 494 LNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEM 553
Query: 603 KESKGQQVCRWHALLE 618
+ + V WH L+E
Sbjct: 554 LANPRKPVEHWHQLVE 569
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 93.2 bits (230), Expect = 6e-19
Identities = 81/316 (25%), Positives = 134/316 (42%), Gaps = 45/316 (14%)
Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363
A G + Y +L+V + D+P + G + V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357
Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
PVF ETF+F+ +E+ + F +Y R + ++G+ + L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403
Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
+LE + + E E + E+ L Y T GRL+ +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453
Query: 483 KGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQ 542
K S+ K + L G D YVK +L+ S G+ + K KTSI++
Sbjct: 454 KASNLKAM--------------DLTG-----FSDPYVKASLI-SEGRRLKKRKTSIKKNT 493
Query: 543 PNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEM 602
NP Y E VF VA + +V L ++V + + E+IG +G +++ HW EM
Sbjct: 494 LNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEM 553
Query: 603 KESKGQQVCRWHALLE 618
+ + V WH L+E
Sbjct: 554 LANPRKPVEHWHQLVE 569
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 93.2 bits (230), Expect = 6e-19
Identities = 81/316 (25%), Positives = 134/316 (42%), Gaps = 45/316 (14%)
Query: 304 AKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQR 363
A G + Y +L+V + D+P + G + V + LLP +K++ +T + R
Sbjct: 298 APCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHR 357
Query: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
PVF ETF+F+ +E+ + F +Y R + ++G+ + L
Sbjct: 358 KTLNPVFNETFQFSVPLAEL-AQRKLHFSVYDFDRFSRHDLIGQVV-------------L 403
Query: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
+LE + + E E + E+ L Y T GRL+ +I
Sbjct: 404 DNLLELAEQPPDRPLWRDIVEGGS----------EKADLGELNFSLCYLPTAGRLTVTII 453
Query: 483 KGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQ 542
K S+ K + L G D YVK +L+ S G+ + K KTSI++
Sbjct: 454 KASNLKAM--------------DLTG-----FSDPYVKASLI-SEGRRLKKRKTSIKKNT 493
Query: 543 PNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEM 602
NP Y E VF VA + +V L ++V + + E+IG +G +++ HW EM
Sbjct: 494 LNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPHGREHWAEM 553
Query: 603 KESKGQQVCRWHALLE 618
+ + V WH L+E
Sbjct: 554 LANPRKPVEHWHQLVE 569
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 93.2 bits (230), Expect = 6e-19
Identities = 82/327 (25%), Positives = 139/327 (42%), Gaps = 51/327 (15%)
Query: 295 PKPFDPEPEA----KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLL 350
P P P + + G L + DYD Q +LLV + + + G + V + LL
Sbjct: 94 PAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLL 153
Query: 351 PIKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF 409
P K++R +T + R P F ETF F E+ G V +Y R + +GE
Sbjct: 154 PDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLV-MAVYDFDRFSRNDAIGEVRV 212
Query: 410 YLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLL 469
++ ++L PV + E + +I L
Sbjct: 213 PMSSVDL----GRPV--------------------QAWRELQAAPREEQEKLGDICFSLR 248
Query: 470 YNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQ 529
Y T G+L+ V++ + K + +GG + D YVK+ LL G+
Sbjct: 249 YVPTAGKLTVIVLEAKNLKKMD---------------VGG----LSDPYVKVHLLQG-GK 288
Query: 530 EMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLN 589
++ K KT+I++ NP Y E F F+V Q+ V + L+V + + + E IG +++G
Sbjct: 289 KVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA- 347
Query: 590 SSGEEELNHWTEMKESKGQQVCRWHAL 616
++G L HW +M + + + +WH+L
Sbjct: 348 AAGGAGLRHWADMLANPRRPIAQWHSL 374
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 84.7 bits (208), Expect = 2e-16
Identities = 75/319 (23%), Positives = 134/319 (42%), Gaps = 58/319 (18%)
Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
G L+ YD ++L+V + ++P + +G + V + LLP +K + +T + R
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281
Query: 367 -PVFTETFKF----NHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIF--YLTKLNLQGK 419
PVF E F F N +E+ + F +Y R + ++G+ + +L + +
Sbjct: 282 NPVFDEVFLFPVPYNDLEARKL-----HFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRE 336
Query: 420 MSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSA 479
L +E N ++ + E++ L Y T GRL+
Sbjct: 337 CILWKDIEYVTN-------------------------DNVDLGELMFSLCYLPTAGRLTI 371
Query: 480 EVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIR 539
+IK + K + + D YVK++L+ G+ + K KTS +
Sbjct: 372 TIIKARNLKAM-------------------DITGASDPYVKVSLMCD-GRRLKKRKTSTK 411
Query: 540 RGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHW 599
R NPVY E VF V + + L ++V + + E+IG +G N + +HW
Sbjct: 412 RNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVG-NEAERLGRDHW 470
Query: 600 TEMKESKGQQVCRWHALLE 618
+EM + + WH+L+E
Sbjct: 471 SEMLSYPRKPIAHWHSLVE 489
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 84.3 bits (207), Expect = 3e-16
Identities = 76/310 (24%), Positives = 132/310 (42%), Gaps = 45/310 (14%)
Query: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366
G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR
Sbjct: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213
Query: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426
+F + ++ + ++RF ++G+ ++ G L+ L+L L
Sbjct: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265
Query: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486
+P Q ++ +V EIL+ L Y T RL+ V+K
Sbjct: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKA-- 307
Query: 487 FKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPV 546
K+LI D +VK+ LL G++MSK KT+++R PNPV
Sbjct: 308 -----------------KNLIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPV 349
Query: 547 YKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK 606
+ E +F V L D++L ++V S R + +G + +G ++SG HW +M +
Sbjct: 350 FNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATL 408
Query: 607 GQQVCRWHAL 616
+ V WHA+
Sbjct: 409 RRPVSMWHAV 418
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 82.8 bits (203), Expect = 9e-16
Identities = 93/380 (24%), Positives = 156/380 (41%), Gaps = 54/380 (14%)
Query: 251 PSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLP-KPFDPEPEAK---- 305
P+ G S + +EDV A S S S ++ P KP + EP+A
Sbjct: 62 PAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGPSPGPSPARPPAKPPEDEPDADGYES 121
Query: 306 -----YGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLP----IKKQR 356
GTLD + YD + L T+T + + G V L LLP K R
Sbjct: 122 DDCTALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLR 181
Query: 357 AKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL 416
KT ++ P + ET + + E + +R + + + + +GE L KL
Sbjct: 182 TKT-LRNTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKP 240
Query: 417 QGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGR 476
+ + LE Q+ V + + +SLE ILI L Y++
Sbjct: 241 NHTKTFNICLE---------KQLPVDK-------TEDKSLEERG--RILISLKYSSQKQG 282
Query: 477 LSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKT 536
L +++ +H + AN D YVK T L + SK KT
Sbjct: 283 LLVGIVRCAHLAAMDANG-------------------YSDPYVK-TYLRPDVDKKSKHKT 322
Query: 537 SIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEEL 596
++++ NP + E F +++ L+ +L ++V++ K + IG + LG+++ G E L
Sbjct: 323 AVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKG-ERL 381
Query: 597 NHWTEMKESKGQQVCRWHAL 616
HW + ++K +++ RWH L
Sbjct: 382 KHWFDCLKNKDKRIERWHTL 401
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 81.3 bits (199), Expect = 2e-15
Identities = 88/357 (24%), Positives = 144/357 (40%), Gaps = 62/357 (17%)
Query: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKY--GTLDVTFDYDSQEQKLLVTVTAVT 330
P D P S +S + D E +KY G L + YD L V V
Sbjct: 150 PDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEAR 209
Query: 331 DIPT-YNRTGGNSWQVH------LVLLPIKKQRAKTSIQRGPC-PVFTE--TFKFNHVES 380
D+P + G H + LLP +K +T ++R PVF E TF+ +E+
Sbjct: 210 DLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEA 269
Query: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNL-QGKMSLPVILEPSYNHSGCDSQM 439
+ + + + + ++G+ L +++L +G ++ S N
Sbjct: 270 Q---RRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNE------- 319
Query: 440 SVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGL 499
+E G E+L+ L Y + GRL+ +VI+
Sbjct: 320 ----------------VELG---ELLLSLNYLPSAGRLNVDVIRA--------------- 345
Query: 500 FCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQ 559
K L+ V D +VK+ L++ + +K KTS RG +P Y E+F F+V +
Sbjct: 346 ----KQLLQTDVSQGSDPFVKIQLVHGLKLVKTK-KTSFLRGTIDPFYNESFSFKVPQEE 400
Query: 560 LSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 616
L + +L+ +V+ + IG I +G SSG E NHW M + V +WH+L
Sbjct: 401 LENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 77.0 bits (188), Expect = 5e-14
Identities = 86/347 (24%), Positives = 138/347 (39%), Gaps = 27/347 (7%)
Query: 273 PSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDI 332
P+ +PED + S +D + GTL+ YD L ++ +
Sbjct: 64 PAALLGATTPEDGAEVDS-------YDSDDATALGTLEFDLLYDRASCTLHCSILRAKGL 116
Query: 333 PTYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGPC-PVFTETFKFNHVESEMIGNYAVR 389
+ G V L LLP K + KT QR PV+ E ++ + + I + +R
Sbjct: 117 KPMDFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLR 176
Query: 390 FRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSES 449
+ ++ + +GE L +L K + LE + S MS + S
Sbjct: 177 IAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLAS-PSSMSAALRGISCY 235
Query: 450 TSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGG 509
+ E G GLL GR+ + S + L G+ C HL
Sbjct: 236 LKELEQAEQGQ------GLLEER--GRILLSLSYSSRRRGLLV-----GILRCA-HLAAM 281
Query: 510 QVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSV 569
V D YVK T L + SK KT +++ NP + E F +++ L L+ TL ++V
Sbjct: 282 DVNGYSDPYVK-TYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTV 340
Query: 570 YNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 616
++ K + IG +SLG + GE HW++ + + RWH L
Sbjct: 341 WDYDIGKSNDFIGGVSLGPGARGEAR-KHWSDCLQQPDAALERWHTL 386
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 75.1 bits (183), Expect = 2e-13
Identities = 83/320 (25%), Positives = 136/320 (42%), Gaps = 53/320 (16%)
Query: 302 PEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSI 361
P+ G L + +Y+ + ++LLV + + + T S V L LLP +++ ++
Sbjct: 144 PDGCLGRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC--SPLVKLYLLPDERRFLQSKT 201
Query: 362 QRGPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKM 420
+R P F E F F V S+ I ++F +Y V R +K +++G+ +F L L G
Sbjct: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDC 260
Query: 421 SLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGS-VPEILIGLLYNATTGRLSA 479
+ + +SLE S ++ L YN RL+
Sbjct: 261 RRVIWRD-----------------------LEAESLEPPSEFGDLQFCLSYNDYLSRLTV 297
Query: 480 EVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCK-TSI 538
V++ + L +R I +VK++L+N + KCK TS
Sbjct: 298 VVLRAKGLR-LQEDRG------------------IVSVFVKVSLMNH--NKFVKCKKTSA 336
Query: 539 RRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLG--LNSSGEEEL 596
G NPVY ETF F+ +L +L L+V + + +G + +G + + G EL
Sbjct: 337 VLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQLGRVVVGPYMYTRG-REL 395
Query: 597 NHWTEMKESKGQQVCRWHAL 616
HW EM + V RWHAL
Sbjct: 396 EHWDEMLSKPKELVKRWHAL 415
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 73.2 bits (178), Expect = 7e-13
Identities = 74/319 (23%), Positives = 136/319 (42%), Gaps = 56/319 (17%)
Query: 300 PEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKK-QRAK 358
P ++G L ++ ++D Q++ V + D+ R GG V + + R +
Sbjct: 112 PGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL----RPGGTVDPYARVSVSTQAGHRHE 167
Query: 359 TSIQRGP-CPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQ 417
T + RG CPVF ET F+ ++E+ G ++ +L+ R + +GE L ++LQ
Sbjct: 168 TKVHRGTLCPVFDETCCFHIPQAELPGA-TLQVQLFNFKRFSGHEPLGELRLPLGTVDLQ 226
Query: 418 GKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRL 477
+ +L P + + V E+ L Y ++GRL
Sbjct: 227 HVLEHWYLLGPP------------------------AATQPEQVGELCFSLRYVPSSGRL 262
Query: 478 SAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTS 537
+ V++ RP + + YVK+ L+ + ++ K KT+
Sbjct: 263 TVVVLEARGL------RPG-----------------LAEPYVKVQLMLNQ-RKWKKRKTA 298
Query: 538 IRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELN 597
++G P + E F F V Q+ +V L+L+V+++ R E +G + LG +SG + L
Sbjct: 299 TKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASG-QPLQ 357
Query: 598 HWTEMKESKGQQVCRWHAL 616
HW +M + + + H L
Sbjct: 358 HWADMLAHARRPIAQRHPL 376
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 72.0 bits (175), Expect = 2e-12
Identities = 91/356 (25%), Positives = 142/356 (39%), Gaps = 61/356 (17%)
Query: 280 LSPEDMSAQGSSSQLPKPFDPEPEAK------YGTLDVTFDYDSQEQKLLVTVTAVTDIP 333
L P SA S+ QL DPEPE GTL+ T +++ L T +
Sbjct: 109 LRPAAASAVRSAPQLQP--DPEPEGDSDDSTALGTLEFTLLFEADNSALHCTAHRAKGLK 166
Query: 334 TYNRTGGNSWQVHLVLLP--IKKQRAKTSIQRGP-CPVFTETFKFNH----------VES 380
+G V LLP K + +T RG PV+ ET ++ + S
Sbjct: 167 PL-ASGSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRS 225
Query: 381 EMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMS 440
++ G+ AV R V R + +GE L KL S + LE +
Sbjct: 226 DLGGHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDICLE----------KRR 275
Query: 441 VSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLF 500
+ E+ + C +L+ L Y++ G L V++ +H + AN
Sbjct: 276 LEEVETEVAWEECG--------HVLLSLCYSSQQGGLLVGVLRCAHLAPMDANG------ 321
Query: 501 CCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQL 560
D +V+L L + G++ SK KTS+ R NP + E F + +L
Sbjct: 322 -------------YSDPFVRLFLHPNAGKK-SKFKTSVHRKTLNPEFNEEFFYSGPREEL 367
Query: 561 SDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 616
+ TL++SV++ + IG + LG ++SG E L HW E ++ WH L
Sbjct: 368 AQKTLLVSVWDYDLGTADDFIGGVQLGSHASG-ERLRHWLECLGHSDHRLKLWHPL 422
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 60.5 bits (145), Expect = 5e-09
Identities = 78/324 (24%), Positives = 133/324 (41%), Gaps = 52/324 (16%)
Query: 298 FDPEPEAKYGT---LDVTFDYDSQEQKLLVT-VTAVTDIPTYNRTGGNSWQVH-LVLLPI 352
++PE A + L DYD Q+ +L VT + AVT N GG V V
Sbjct: 148 WNPEKAASWNQAPKLHYCLDYDCQKAELFVTRLEAVTS----NHDGGCDCYVQGSVANRT 203
Query: 353 KKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLT 412
A+T++++ E + E + + L R + + GE
Sbjct: 204 GSVEAQTALKKRQLHTTWEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGE-----L 258
Query: 413 KLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNA 472
+L L G + + + E +S + G+ E+L+ + Y
Sbjct: 259 RLGLDG------------------TSVPLGAAQWGELKTSAKEPSAGA-GEVLLSISYLP 299
Query: 473 TTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMS 532
RL +IK KNL +N+ K L+G +D VK+TL + +++
Sbjct: 300 AANRLLVVLIKA---KNLHSNQS--------KELLG------KDVSVKVTLKHQ-ARKLK 341
Query: 533 KCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSG 592
K +T + + NPV+ E +F++ L ++ L V + + +G SLGL++SG
Sbjct: 342 KKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHTSG 401
Query: 593 EEELNHWTEMKESKGQQVCRWHAL 616
E +HW EM ++ +Q+ WH L
Sbjct: 402 SER-SHWEEMLKNPRRQIAMWHQL 424
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,778,322
Number of Sequences: 37866
Number of extensions: 1176870
Number of successful extensions: 3869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 3654
Number of HSP's gapped (non-prelim): 201
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.